BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453810 netrin 3 [Homo sapiens] (580 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453810 netrin 3 [Homo sapiens] 1241 0.0 gi|148613884 netrin 1 [Homo sapiens] 674 0.0 gi|24308065 netrin 5 [Homo sapiens] 377 e-104 gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 327 2e-89 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 306 4e-83 gi|93204871 netrin 4 [Homo sapiens] 228 2e-59 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 227 2e-59 gi|143770880 laminin, beta 4 [Homo sapiens] 210 3e-54 gi|164414431 netrin G1 isoform 1 [Homo sapiens] 199 8e-51 gi|167614504 laminin, beta 1 precursor [Homo sapiens] 198 1e-50 gi|62868217 laminin, beta 3 precursor [Homo sapiens] 196 5e-50 gi|62868215 laminin, beta 3 precursor [Homo sapiens] 196 5e-50 gi|189083719 laminin, beta 3 precursor [Homo sapiens] 196 5e-50 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 195 8e-50 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 195 8e-50 gi|190014607 netrin G2 [Homo sapiens] 194 1e-49 gi|21264602 laminin alpha 5 [Homo sapiens] 193 4e-49 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 190 3e-48 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 167 2e-41 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 167 2e-41 gi|219842266 usherin isoform B [Homo sapiens] 163 5e-40 gi|219842259 usherin isoform A [Homo sapiens] 163 5e-40 gi|54312078 netrin G1 isoform 3 [Homo sapiens] 124 2e-28 gi|164414437 netrin G1 isoform 2 [Homo sapiens] 123 5e-28 gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 105 1e-22 gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 105 1e-22 gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 96 1e-19 gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 96 1e-19 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 91 4e-18 gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 86 7e-17 >gi|5453810 netrin 3 [Homo sapiens] Length = 580 Score = 1241 bits (3212), Expect = 0.0 Identities = 580/580 (100%), Positives = 580/580 (100%) Query: 1 MPGWPWGLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCG 60 MPGWPWGLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCG Sbjct: 1 MPGWPWGLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCG 60 Query: 61 RPATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFV 120 RPATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFV Sbjct: 61 RPATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFV 120 Query: 121 SLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA 180 SLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA Sbjct: 121 SLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA 180 Query: 181 PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVV 240 PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVV Sbjct: 181 PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVV 240 Query: 241 PYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRA 300 PYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRA Sbjct: 241 PYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRA 300 Query: 301 TARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD 360 TARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD Sbjct: 301 TARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD 360 Query: 361 PGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAP 420 PGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAP Sbjct: 361 PGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAP 420 Query: 421 CVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAW 480 CVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAW Sbjct: 421 CVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAW 480 Query: 481 TRFPVAVLAVFRSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAG 540 TRFPVAVLAVFRSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAG Sbjct: 481 TRFPVAVLAVFRSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAG 540 Query: 541 GRGPGLIAARGSLVLPWRDAWTRRLRRLQRRERRGRCSAA 580 GRGPGLIAARGSLVLPWRDAWTRRLRRLQRRERRGRCSAA Sbjct: 541 GRGPGLIAARGSLVLPWRDAWTRRLRRLQRRERRGRCSAA 580 >gi|148613884 netrin 1 [Homo sapiens] Length = 604 Score = 674 bits (1740), Expect = 0.0 Identities = 314/580 (54%), Positives = 406/580 (70%), Gaps = 29/580 (5%) Query: 22 GPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATR---------------- 65 G A DPC DE G PR C+P VNAA G++V SSTCGRP R Sbjct: 33 GQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVSERGEERLRSCH 92 Query: 66 ACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFC 125 C+ASDP++AH PA LT + CW+SE+ + P NVTLT+ LGK FE+ +VSL+FC Sbjct: 93 LCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFC 152 Query: 126 SAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPL-AQ 184 S P S+A+ KS D+GR+W P F+S+ C Y R P A EA+C + + Sbjct: 153 SPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNR-PHRAPITKQNEQEAVCTDSHTDMR 211 Query: 185 PDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVP--- 241 P GL+AFS D P D D+SPVLQDWVTATD+RV +R T GD + ++ + Sbjct: 212 PLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDS 271 Query: 242 YSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT 301 Y YA +DLQVGGRCKCNGHA+RC+ D L+CDCRH T GP+C RCKPF+ DRPWQRAT Sbjct: 272 YFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRAT 331 Query: 302 ARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDP 361 ARE++ C+AC+CN HARRCRFNMELY+LSGR+SGGVCLNCRHNTAGRHCHYC+EG+YRD Sbjct: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391 Query: 362 GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421 G+ ++ R+AC+ACDCHPVGAAGKTCNQTTGQCPCKDGVTG+TCNRCA G+QQSRSP+APC Sbjct: 392 GKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451 Query: 422 VKTPIPGPTEDSSPV-QPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAW 480 +K P+ PT +S V +P+DCDS+CK ++G +I++KK+CKKDYAVQ+ + + + G W Sbjct: 452 IKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHI-LKADKAGDW 510 Query: 481 TRFPVAVLAVFRSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAG 540 +F V +++V++ G R RRG +LW+ + D AC CP++ P ++YLLLG + Sbjct: 511 WKFTVNIISVYKQGTSRIRRGDQSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSPDQS-- 568 Query: 541 GRGPGLIAARGSLVLPWRDAWTRRLRRLQRRERRGRCSAA 580 G++A + SLV+ WRD W RRLR+ Q+RE++G+C A Sbjct: 569 ----GIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKKA 604 >gi|24308065 netrin 5 [Homo sapiens] Length = 489 Score = 377 bits (968), Expect = e-104 Identities = 229/566 (40%), Positives = 283/566 (50%), Gaps = 99/566 (17%) Query: 16 FAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRACDASDPRRA 75 FA L A ADPC+D G P+ C+P + A A AS P+ Sbjct: 5 FALLLLLGQATADPCYDPQGRPQFCLPPVTQLA-----------------AVAASCPQ-- 45 Query: 76 HSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALL 135 A SPG R N +LT+ LG F L VSLRFC+ P ++ L Sbjct: 46 ---ACALSPGNHLGA---------RETCNGSLTLALGGPFLLTSVSLRFCTPGPPALILS 93 Query: 136 KSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDGSGLLAFSM 195 + G W L PA A GPE + F Sbjct: 94 AAWASGGPWRLLWH-------------RPAWPGALGGPERVTF----------------- 123 Query: 196 QDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRC 255 S+P + V A+ +RV + AA L+ GRC Sbjct: 124 ----------HSTPGPKATVAASHLRVEFGGQA--------------GLAAAGLR--GRC 157 Query: 256 KCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNG 315 +C+GHA+RC + C CRH T GP C C+P + D PW+ AT R H CL CSCN Sbjct: 158 QCHGHAARCAARARPPR-CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216 Query: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375 HARRCRFN EL+RLSG RSGGVC CRH+TAGRHCHYC+ GF+RDP + + RRACRAC Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276 Query: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSP 435 CHP+GA G TCNQT+GQC CK GVTGLTCNRC PG+QQSRSP PC + P T ++P Sbjct: 277 CHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTP 336 Query: 436 ----VQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAWTRFPVAVLAVF 491 PQ C ++C + +SL+++C++D+ ++ V A A AW R V VLAV+ Sbjct: 337 GAYSSDPQ-CQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASEAAGPAWQRLAVRVLAVY 395 Query: 492 RSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAGGRGPGLIAARG 551 + + RRG WVP D CGC RL PG YLLLG G LI R Sbjct: 396 KQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVG------DPDPTRLILDRH 449 Query: 552 SLVLPWRDAWTRRLRRLQRRERRGRC 577 L LPWR W R L+RLQ+ ER G C Sbjct: 450 GLALPWRPRWARPLKRLQQEERAGGC 475 >gi|145309326 laminin, gamma 1 precursor [Homo sapiens] Length = 1609 Score = 327 bits (837), Expect = 2e-89 Identities = 176/444 (39%), Positives = 238/444 (53%), Gaps = 34/444 (7%) Query: 4 WPWGLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRP- 62 WP +L A AA + A D C DEGG P+ C+P VNAA V+A++TCG P Sbjct: 18 WPVLAVLAA----AAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPP 73 Query: 63 --------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESL---PRAPLNV 105 + CDA P H A LT A W+S+++ + P ++ Sbjct: 74 EEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSI 133 Query: 106 TLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPA 165 LT+ LGKAF++ +V L+F ++ P S A+ K W P ++S C+ Y + Sbjct: 134 NLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGF 193 Query: 166 NGPAGPGPEALCFPA-PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVL 224 G +ALC P G +AFS + P + D+SPVLQ+WVTATD+RV L Sbjct: 194 IRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTL 253 Query: 225 TRPSTAGDP--RDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEG 282 R +T GD D + + Y YA +D VGGRCKCNGHAS C+ + L+C+C+H T G Sbjct: 254 NRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYG 313 Query: 283 PDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCR 342 DC +C PF+ DRPW+RATA + CL C CNG ++ C F+ ELYR +G GG C NC+ Sbjct: 314 VDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCQ 371 Query: 343 HNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGL 402 NT G HC CRE F+R L + AC +C C PVG+ C+ + G+C CK GV G Sbjct: 372 DNTDGAHCERCRENFFR-----LGNNEACSSCHCSPVGSLSTQCD-SYGRCSCKPGVMGD 425 Query: 403 TCNRCAPGFQQ-SRSPVAPCVKTP 425 C+RC PGF + + PC P Sbjct: 426 KCDRCQPGFHSLTEAGCRPCSCDP 449 Score = 92.8 bits (229), Expect = 8e-19 Identities = 67/230 (29%), Positives = 91/230 (39%), Gaps = 41/230 (17%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314 C CNGH+ C +T +C+CR T GP C +C Y + +TA S C C C Sbjct: 724 CACNGHSETCDPETG---VCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQPCPCP 776 Query: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 G + + + VC NC T G+ C C +G++ DP R CR C Sbjct: 777 GGSSCA--------VVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLC 828 Query: 375 DCH---PVGAAGKTCNQTTGQC-PCKDGVTGLTCNRCAPGFQQSRSPVAPCVK------- 423 C A G CN+ TG+C C G C+RC GF + P K Sbjct: 829 QCSDNIDPNAVG-NCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCN 887 Query: 424 -----------TPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKK 462 P+ G E V QDC + C P G Y + + C++ Sbjct: 888 LYGTMKQQSSCNPVTGQCECLPHVTGQDCGA-CDP--GFYNLQSGQGCER 934 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/144 (33%), Positives = 58/144 (40%), Gaps = 28/144 (19%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARES--HACLACSCNGHARRCRFNMELYRLSG 331 C C G G C C Y +R T C+ C+CNGH+ C Sbjct: 690 CTCPVGYGGQFCEMCLSGY-----RRETPNLGPYSPCVLCACNGHSETC----------- 733 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA----GKTCN 387 GVC NCR NTAG HC C +G+Y D S C+ C C P G++ KT Sbjct: 734 DPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSS--DCQPCPC-PGGSSCAVVPKTKE 789 Query: 388 QTTGQCPCKDGVTGLTCNRCAPGF 411 CP G TG C C G+ Sbjct: 790 VVCTNCP--TGTTGKRCELCDDGY 811 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 29/146 (19%) Query: 274 CDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 C+C G DCG C P FY + C C C+ L +G+ Sbjct: 905 CECLPHVTGQDCGACDPGFY--------NLQSGQGCERCDCHA----------LGSTNGQ 946 Query: 333 RS--GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTT 390 G C C+ G+HC C + C+ CDCHP G+ C Sbjct: 947 CDIRTGQC-ECQPGITGQHCERCEVNHFG------FGPEGCKPCDCHPEGSLSLQCKDD- 998 Query: 391 GQCPCKDGVTGLTCNRCAPGFQQSRS 416 G+C C++G G C++C + +RS Sbjct: 999 GRCECREGFVGNRCDQCEENYFYNRS 1024 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 306 bits (783), Expect = 4e-83 Identities = 166/419 (39%), Positives = 219/419 (52%), Gaps = 32/419 (7%) Query: 30 CHDEGGAPRGCVPGLVNAALGREVLASSTCGRPAT---------------RACDASDPRR 74 C+D G P+ C+P NAA GR AS TCG P + CDA+DP+R Sbjct: 25 CYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFCPHVGAAGAGAHCQRCDAADPQR 84 Query: 75 AHSPALLTSPGGTASPLCWRSESLP---RAPLNVTLTVPLGKAFELVFVSLRFCSAPPAS 131 H+ + LT W+S S+ + P +V +T+ LGKA+E+ +V L+F ++ P S Sbjct: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144 Query: 132 VALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA-PLAQPDGSGL 190 A+ K W P F+S+ C YGR P A C P G Sbjct: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204 Query: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDP--RDMEAVVPYSYAATD 248 +AFS + P + + SP LQ+WVT+T++ + L R +T GD +D + + Y YA +D Sbjct: 205 VAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSD 264 Query: 249 LQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHAC 308 VGGRCKCNGHAS C D G L C C+H T G DC RC PF+ DRPW R TA +H C Sbjct: 265 FSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHEC 324 Query: 309 LACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR-DPGRALSD 367 L C+C+G + C F+ EL+R +G GG C +CR +TAG HC C+E FY DP Sbjct: 325 LPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYHWDP------ 376 Query: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVKTP 425 R C+ CDC G+ C+ TG C CK VTG C+RC PGF S PC P Sbjct: 377 RMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNP 434 Score = 95.1 bits (235), Expect = 2e-19 Identities = 94/331 (28%), Positives = 110/331 (33%), Gaps = 115/331 (34%) Query: 180 APLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLT----RPSTAGDPRD 235 +P P G L S+ PGL +S WV T G R+ Sbjct: 640 SPGPSPAGPVFLTEVRLTSARPGLSPPAS-----WVEICSCPTGYTGQFCESCAPGYKRE 694 Query: 236 MEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKP-FY-- 292 M PY+ C CN H + C +T IC C H TEGP C RC P FY Sbjct: 695 MPQGGPYASCVP-------CTCNQHGT-CDPNTG---ICVCSHHTEGPSCERCLPGFYGN 743 Query: 293 -----------CDRPWQRA--TARESH--ACLACSCNGHARRCR-----FNMELYRLSGR 332 C P Q A T ES C C RRC F + L G Sbjct: 744 PFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGH 803 Query: 333 RS----------------------GGVCLNCRHNTAGRHCHYCREGFY------------ 358 G CL C HNT G HC +C+EGFY Sbjct: 804 PQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKC 863 Query: 359 --------------------------------RDPGRA------LSDRRACRACDCHPVG 380 RD R L R CR+C CHP+G Sbjct: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923 Query: 381 AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 + C+ TGQC C+ GVTG C+RC GF Sbjct: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 29/141 (20%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN---GHARRCRFNMELYRLS 330 C C DC RC P + D + C +C C+ +C Sbjct: 887 CSCLPHVTARDCSRCYPGFFD-------LQPGRGCRSCKCHPLGSQEDQCH--------- 930 Query: 331 GRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTT 390 G C CR G+ C C+ GF+ G ++ + CRAC C P+GAA C++ Sbjct: 931 --PKTGQC-TCRPGVTGQACDRCQLGFF---GFSI---KGCRACRCSPLGAASAQCHE-N 980 Query: 391 GQCPCKDGVTGLTCNRCAPGF 411 G C C+ G G C+RC F Sbjct: 981 GTCVCRPGFEGYKCDRCHDNF 1001 >gi|93204871 netrin 4 [Homo sapiens] Length = 628 Score = 228 bits (580), Expect = 2e-59 Identities = 187/652 (28%), Positives = 277/652 (42%), Gaps = 120/652 (18%) Query: 8 LLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRA- 66 LLL T+ AA G + C + C P + N ALGR++ A +TCG+ AT Sbjct: 8 LLLWGCTVVAAGLSGVAGVSSRCE------KACNPRMGNLALGRKLWADTTCGQNATELY 61 Query: 67 ------------------CDASDPRRAHSPALLTSPGGTASPLCWRS-ESLPRAPLNVTL 107 C+A+ P AH P+ + W+S E + R + + L Sbjct: 62 CFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDL 121 Query: 108 TVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANG 167 F + + F S PA++ L +SQD G++W P +F+++C +G Sbjct: 122 EAE----FYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVK- 176 Query: 168 PAGPGPEALC---FPAPLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRV-V 223 A+C + +P P G + F S P + S +Q+ + T++RV + Sbjct: 177 -----KGAICTSKYSSPF--PCTGGEVIFKAL-SPPYDTENPYSAKVQEQLKITNLRVQL 228 Query: 224 LTRPSTAGDPRDMEAVVPY--SYAATDLQVGGRCKCNGHASRCL-------LDTQG--HL 272 L R S D+ + YA D V G C CNGHA +C+ + G H+ Sbjct: 229 LKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHM 288 Query: 273 I---CDCRHGTEGPDCGRCKPFYCDRPWQRATARES--HACLACSCNGHARRCRFNMELY 327 + C C+H T G C C P Y DRPW+ A + + C C CNGHA C F++ ++ Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVW 348 Query: 328 RLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCN 387 SG RSGGVC +C+HNT G++C C+ GFYRD R S AC+ C CHPVG+A N Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408 Query: 388 QTT------GQCPCKDGVTGLTCNRCAPGF-------------QQSRSPV-APCVKT--- 424 T G CPCK GV G C+RC G+ S P+ C+ + Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTD 468 Query: 425 -----------PIPGPTED----------SSPVQPQDCDSHCKPARGSYRISLKKFC--K 461 P+ +E S+ + C+ CK + K FC K Sbjct: 469 IDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCE--CKEQTLG---NAKAFCGMK 523 Query: 462 KDYAVQVAVGARGEARGAWTRFPVAVLAVFRSGEERARRGSSALWVPA-GDAACGCPRLL 520 Y +++ + +G V + V +S + + RG L+ + D C CP L Sbjct: 524 YSYVLKIKI-LSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILN 582 Query: 521 PGRRYLLLGGGPGAAAGGAGGRGPGLIAARGSLVLPWRDAWTRRLRRLQRRE 572 PG YL+ AG R LI S V W+ + R++ + +RE Sbjct: 583 PGLEYLV--------AGHEDIRTGKLIVNMKSFVQHWKPSLGRKVMDILKRE 626 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 227 bits (579), Expect = 2e-59 Identities = 166/496 (33%), Positives = 223/496 (44%), Gaps = 70/496 (14%) Query: 5 PW----GLLLTAGTLFAALSPGPPAPADPCHDEGGAPRG-CVPGLVNAALGR--EVLASS 57 PW GLLL+ A +P P P G RG C P + +GR + ASS Sbjct: 15 PWELRLGLLLSVLAATLAQAPAPDVP--------GCSRGSCYPATGDLLVGRADRLTASS 66 Query: 58 TCGRPAT------------RACDASDPRRAHSPA----------LLTSPGGTASPLCWRS 95 TCG + C D RR S ++TS W+S Sbjct: 67 TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS 126 Query: 96 ESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCD 155 E+ A VT+ + L F + + F + PA++ + +S D GR+W +FS C Sbjct: 127 ENGIPA---VTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCG 183 Query: 156 LDYGRLPAPANGPAGPGPEALCFPA-PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDW 214 D+ +P P + +C +P G + + + D + P D SS + Q+ Sbjct: 184 ADFPGVPL---APPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRI-QNL 239 Query: 215 VTATDVRVVLTRPSTAGD----PRDMEAVVPYSYAATDLQVGGRCKCNGHASRCL----- 265 + T++RV LTR T GD PR E Y YA +L V G C C GHAS C Sbjct: 240 LKITNLRVNLTRLHTLGDNLLDPR-REIREKYYYALYELVVRGNCFCYGHASECAPAPGA 298 Query: 266 ---LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRF 322 + H C C+H T G +C +C+ FY D PW+ A SHAC C C+GH C F Sbjct: 299 PAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHF 358 Query: 323 NMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA 382 +M +Y SG SGGVC C+HNTAGRHC CR FYRDP + L D CR+CDC P+G+ Sbjct: 359 DMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQ 418 Query: 383 -GKTCNQ--------TTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPC--VKTPIPGPT 430 G C+ +GQC CK+ V G C +C G F S S C + G Sbjct: 419 DGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTV 478 Query: 431 EDSSPVQPQDCDSHCK 446 S+P P +CK Sbjct: 479 PGSTPCDPNSGSCYCK 494 Score = 94.4 bits (233), Expect = 3e-19 Identities = 71/231 (30%), Positives = 89/231 (38%), Gaps = 40/231 (17%) Query: 224 LTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGP 283 L +P G D+ A Y + T Q C+C+ + L + C CR G G Sbjct: 803 LCKPGVVGRRCDLCAPGYYGFGPTGCQA---CQCSHEGALSSLCEKTSGQCLCRTGAFGL 859 Query: 284 DCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRH 343 C RC+ P +C C CNGHA C + G CL CR Sbjct: 860 RCDRCQRGQWGFP----------SCRPCVCNGHADECNTHT-----------GACLGCRD 898 Query: 344 NTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK-----TCNQTTGQ----CP 394 +T G HC C GF+ DP L CR C C P G + +C+Q C Sbjct: 899 HTGGEHCERCIAGFHGDP--RLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCH 955 Query: 395 CKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444 C+ G TGL C CAPG F P C G + P+ P CD H Sbjct: 956 CRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSG---NIDPMDPDACDPH 1003 Score = 85.5 bits (210), Expect = 1e-16 Identities = 56/176 (31%), Positives = 73/176 (41%), Gaps = 30/176 (17%) Query: 254 RCKCN---GHASRCLLDTQGHLI-----CDCRHGTEGPDCGRCKPFYCDRPWQRATARES 305 RC CN + +C Q H C C +GP C RC P + W + Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF----WNLTSG--- 1089 Query: 306 HACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRAL 365 H C C+C H R R + G C +CR GR C C+E + DPG Sbjct: 1090 HGCQPCAC--HPSRARGP------TCNEFTGQC-HCRAGFGGRTCSECQELHWGDPGLQ- 1139 Query: 366 SDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421 C ACDC G C++ TG C C+ GV+G+ C++CA GF PC Sbjct: 1140 -----CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190 Score = 84.0 bits (206), Expect = 4e-16 Identities = 55/171 (32%), Positives = 70/171 (40%), Gaps = 37/171 (21%) Query: 252 GGRCK---------------CNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRP 296 GGRC+ C+ H +CL C H TEGP C CKP + + Sbjct: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLR---------CLHHTEGPHCAHCKPGFHGQ- 1029 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREG 356 AR+S C C+CN + + S G C C N G C C Sbjct: 1030 ----AARQS--CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC-PCLPNVQGPSCDRCAPN 1082 Query: 357 FYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407 F+ L+ C+ C CHP A G TCN+ TGQC C+ G G TC+ C Sbjct: 1083 FWN-----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128 Score = 74.3 bits (181), Expect = 3e-13 Identities = 56/222 (25%), Positives = 82/222 (36%), Gaps = 72/222 (32%) Query: 254 RCKCNGHASRCLLDTQGHL--------ICD-CRHGTEGPDCGRCKPFYCDRPWQRATARE 304 +C+C+GH C D +L +CD C+H T G C C+PF+ P + R+ Sbjct: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK--DLRD 403 Query: 305 SHACLACSCNGHAR----RCRFNME--LYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 C +C C+ RC + + L +SG+ C+ + G C CR+GF+ Sbjct: 404 PAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQ------CRCKEHVVGTRCQQCRDGFF 457 Query: 359 R--------------------------DP------------GRALS-----------DRR 369 DP GR D Sbjct: 458 GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517 Query: 370 ACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 CR CDC GA C++ TGQC C+ + G C + PG+ Sbjct: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/88 (38%), Positives = 41/88 (46%), Gaps = 8/88 (9%) Query: 335 GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCP 394 GG CL C+ GR C C G+Y C+AC C GA C +T+GQC Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYYG------FGPTGCQACQCSHEGALSSLCEKTSGQCL 851 Query: 395 CKDGVTGLTCNRCAPGFQQSRSPVAPCV 422 C+ G GL C+RC G Q PCV Sbjct: 852 CRTGAFGLRCDRCQRG-QWGFPSCRPCV 878 Score = 50.4 bits (119), Expect = 4e-06 Identities = 19/38 (50%), Positives = 23/38 (60%) Query: 374 CDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 C C+P G+ CN GQC CK GV G C+ CAPG+ Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGY 820 Score = 31.6 bits (70), Expect = 2.1 Identities = 28/114 (24%), Positives = 42/114 (36%), Gaps = 29/114 (25%) Query: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306 RC+CN + G CD C+ G C RC P + W + + Sbjct: 469 RCQCNARGT-----VPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLL 517 Query: 307 ACLACSCN-GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR 359 C C C+ G A + + G C +CR + GR C + G++R Sbjct: 518 GCRPCDCDVGGALDPQCD---------EGTGQC-HCRQHMVGRRCEQVQPGYFR 561 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 210 bits (534), Expect = 3e-54 Identities = 135/421 (32%), Positives = 202/421 (47%), Gaps = 60/421 (14%) Query: 40 CVPGLVNAALGR--EVLASSTCGRPATRA------------CDASDPRRAHSPA------ 79 C P + +GR +++ASSTCG + C D R + P Sbjct: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYDQPNSH 87 Query: 80 ----LLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALL 135 ++ S W+SE+ +V++ + L F + L F + PA++ + Sbjct: 88 TIENVIVSFEPDREKKWWQSEN---GLDHVSIRLDLEALFRFSHLILTFKTFRPAAMLVE 144 Query: 136 KSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPL-AQPDGSGLLAFS 194 +S D+G +W +F+ C + P +G A + +C +P G + Sbjct: 145 RSTDYGHNWKVFKYFAKDCATSF---PNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLK 201 Query: 195 MQDSSPPGLDLDS--SPVLQDWVTATDVRVVLTRPSTAGDP----RDMEAVVPYSYAATD 248 + D P ++++ SP +QD VT T++R+ T+ T GD R +++ Y YA + Sbjct: 202 VLD---PSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYE 258 Query: 249 LQVGGRCKCNGHASRC---------LLDTQG--HLICDCRHGTEGPDCGRCKPFYCDRPW 297 + V G C CNGHAS C + G H C C+H T+GP+C RCK F+ D PW Sbjct: 259 MIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPW 318 Query: 298 QRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGF 357 + A + +AC +CSCN H+ RC F+M Y SG SGGVC +C+HNT G+HC CR F Sbjct: 319 RPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLF 378 Query: 358 YRDPGRALSDRRACRACDCHPVGA-AGKTC--------NQTTGQCPCKDGVTGLTCNRCA 408 YRDP + +SD AC C+C P G +G C GQC CK+ V G C++C Sbjct: 379 YRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCK 438 Query: 409 P 409 P Sbjct: 439 P 439 Score = 95.1 bits (235), Expect = 2e-19 Identities = 68/204 (33%), Positives = 86/204 (42%), Gaps = 33/204 (16%) Query: 272 LICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHA-CLACSCNGHARRCRFNMELYRL- 329 +IC+C G G CG C + P R S A C C+CN N+++ Sbjct: 936 VICNCLQGYTGTQCGECSTGFYGNP------RISGAPCQPCACNN-------NIDVTDPE 982 Query: 330 SGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---------PVG 380 S R G CL C HNT G +C C+ G Y G AL+ + CR C CH P G Sbjct: 983 SCSRVTGECLRCLHNTQGANCQLCKPGHY---GSALN--QTCRRCSCHASGVSPMECPPG 1037 Query: 381 AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQD 440 C+ TG CPC VTGL C+RCA G+ + P C T SS Sbjct: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGY-WNLVPGRGCQSCDCDPRTSQSSHCDQLT 1096 Query: 441 CDSHCKPARGSYRISLKKFCKKDY 464 CK G R S C+++Y Sbjct: 1097 GQCPCKLGYGGKRCS---ECQENY 1117 Score = 88.2 bits (217), Expect = 2e-17 Identities = 62/242 (25%), Positives = 88/242 (36%), Gaps = 95/242 (39%) Query: 246 ATDLQVGG--RCKCNGHASRCLLDTQGHL--------IC-DCRHGTEGPDCGRCKPFYCD 294 A DLQ C CN H+SRC D +L +C DC+H TEG C RC+P + Sbjct: 321 AADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYR 380 Query: 295 RPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLN-------------- 340 P + T + +AC+ C C+ G SGG+C++ Sbjct: 381 DPLK--TISDPYACIPCECDP--------------DGTISGGICVSHSDPALGSVAGQCL 424 Query: 341 CRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVG-------------------- 380 C+ N G C C+ Y G + +D C+ CDC+P+G Sbjct: 425 CKENVEGAKCDQCKPNHY---GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYV 481 Query: 381 -------------------------------AAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 A C+ GQC C+ VTG +C+ AP Sbjct: 482 TGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541 Query: 410 GF 411 G+ Sbjct: 542 GY 543 Score = 74.3 bits (181), Expect = 3e-13 Identities = 57/194 (29%), Positives = 72/194 (37%), Gaps = 39/194 (20%) Query: 241 PYSYAATDLQVGGRCKCNGHAS------------RCLLDTQGHLICDCRHGTEGPDCGRC 288 P Y + Q RC C HAS CL D C C G C RC Sbjct: 1008 PGHYGSALNQTCRRCSC--HASGVSPMECPPGGGACLCDPVTGA-CPCLPNVTGLACDRC 1064 Query: 289 KPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGR 348 Y W R C +C C+ + +L G C C+ G+ Sbjct: 1065 ADGY----WNLVPGR---GCQSCDCDPRTSQSSHCDQLT--------GQC-PCKLGYGGK 1108 Query: 349 HCHYCREGFYRDP-GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407 C C+E +Y DP GR C CDC+ G C+ TG C C++GV+G C+RC Sbjct: 1109 RCSECQENYYGDPPGR-------CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161 Query: 408 APGFQQSRSPVAPC 421 A G Q C Sbjct: 1162 ARGHSQEFPTCLQC 1175 Score = 69.3 bits (168), Expect = 9e-12 Identities = 41/122 (33%), Positives = 52/122 (42%), Gaps = 15/122 (12%) Query: 290 PFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRH 349 P C+R +A+ +AC C+ S R GG C C+ GR Sbjct: 748 PGACERLIISMSAKLHDGAVACKCHPQGS--------VGSSCSRLGGQC-QCKPLVVGRC 798 Query: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 C C G Y D G C C CHP G+ C+Q TGQCPC V+G C+RC Sbjct: 799 CDRCSTGSY-DLGH-----HGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLA 852 Query: 410 GF 411 G+ Sbjct: 853 GY 854 Score = 68.2 bits (165), Expect = 2e-11 Identities = 61/233 (26%), Positives = 83/233 (35%), Gaps = 53/233 (22%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314 C C+ S+ + Q C C G C RC Y P +C C CN Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866 Query: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 A C G C NC T GR+C C +G+Y +P S + CR C Sbjct: 867 RFAELCD-----------PETGSCFNCGGFTTGRNCERCIDGYYGNP----SSGQPCRPC 911 Query: 375 DCHPVGAAGK----TCNQTTGQ----CPCKDGVTGLTCNRCAPGF----QQSRSPVAPCV 422 C ++ + +C Q C C G TG C C+ GF + S +P PC Sbjct: 912 LCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA 971 Query: 423 KTPIPGPTEDSS-------------PVQPQDCDSHCKPARGSYRISLKKFCKK 462 T+ S Q +C CKP G Y +L + C++ Sbjct: 972 CNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL-CKP--GHYGSALNQTCRR 1021 Score = 63.2 bits (152), Expect = 6e-10 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 29/174 (16%) Query: 310 ACSCNGHARRCRFNMELYRLSGRRSG---GVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366 +C CNGHA CR ++ G G C+ C+HNT G +C C++ F P R + Sbjct: 264 SCFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAA 322 Query: 367 DRR--ACRACDCHPV---------------GAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 D + ACR+C C+ G +G C C+ G C+RC P Sbjct: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED------CQHNTEGQHCDRCRP 376 Query: 410 GFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKD 463 F + IP + + C SH PA GS ++ + CK++ Sbjct: 377 LFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGS--VAGQCLCKEN 428 >gi|164414431 netrin G1 isoform 1 [Homo sapiens] Length = 539 Score = 199 bits (505), Expect = 8e-51 Identities = 127/395 (32%), Positives = 184/395 (46%), Gaps = 52/395 (13%) Query: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103 TCG P CDAS P AH P L+ G W+S + PL Sbjct: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130 Query: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD + Sbjct: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189 Query: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207 + E +C S ++ F ++D + P L LD+ Sbjct: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249 Query: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267 + L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D Sbjct: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309 Query: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT-----ARESHACLA-------CSCNG 315 L C+C H T GPDCG+CK Y RPW + ++ C+ C C G Sbjct: 310 NS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368 Query: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375 H+ RC + L + +C++C+HNT G+HC CR G++R+ L D C C Sbjct: 369 HSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 421 Query: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 C+P+G+ CN +G C CK G TG C+ C PG Sbjct: 422 CNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455 >gi|167614504 laminin, beta 1 precursor [Homo sapiens] Length = 1786 Score = 198 bits (503), Expect = 1e-50 Identities = 144/491 (29%), Positives = 215/491 (43%), Gaps = 61/491 (12%) Query: 7 GLLLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGR--EVLASSTCG--RP 62 GLL F AL +P G A C P + +GR ++ +STCG +P Sbjct: 2 GLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKP 61 Query: 63 ATRA-------------CDASDPRRAH---SPALLTSPGGTASP----LCWRSESLPRAP 102 C++ DP L+ + T +P + W+SE+ Sbjct: 62 EPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSEN---GV 118 Query: 103 LNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 NVT+ + L F + + F + PA++ + +S D G++W +F+ C+ + P Sbjct: 119 ENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF---P 175 Query: 163 APANGPAGPGPEALCFPAPL-AQPDGSGLLAFSMQDSSPPGLDLDS--SPVLQDWVTATD 219 + GP + +C +P G + F D P ++ SP +Q+ + T+ Sbjct: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALD---PAFKIEDPYSPRIQNLLKITN 232 Query: 220 VRVVLTRPSTAGD---PRDMEAVVPYSYAATDLQVGGRCKCNGHASRCL--------LDT 268 +R+ + T GD ME Y YA D+ V G C C GHAS C ++ Sbjct: 233 LRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEG 292 Query: 269 QGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYR 328 H C CRH T+G +C C FY D PW+ A R S+AC C+CN H+ C F+M +Y Sbjct: 293 MVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYL 352 Query: 329 LSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK-TCN 387 +G SGGVC +C+HNT GR+C C+ +Y+ P R + D C C C P G+ + C+ Sbjct: 353 ATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICD 412 Query: 388 QTT--------GQCPCKDGVTGLTCNRCAPGFQ--QSRSPVA--PCVKTPIPGPTEDSSP 435 T GQC CK V G C+ C GF S P C P+ G +P Sbjct: 413 SYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL-GTIPGGNP 471 Query: 436 VQPQDCDSHCK 446 + +CK Sbjct: 472 CDSETGHCYCK 482 Score = 83.6 bits (205), Expect = 5e-16 Identities = 53/170 (31%), Positives = 68/170 (40%), Gaps = 32/170 (18%) Query: 252 GGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 G C+C+ +CL C G +C RC P WQ A+ C C Sbjct: 1042 GSDCQCDKATGQCL----------CLPNVIGQNCDRCAP----NTWQLASGT---GCDPC 1084 Query: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371 +CN + S G C C GR C C+E F+ DP C Sbjct: 1085 NCNA--------AHSFGPSCNEFTGQC-QCMPGFGGRTCSECQELFWGDPDVE------C 1129 Query: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421 RACDC P G C+Q+TGQC C +GV G C++C G+ PC Sbjct: 1130 RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPC 1179 Score = 75.9 bits (185), Expect = 1e-13 Identities = 61/225 (27%), Positives = 87/225 (38%), Gaps = 65/225 (28%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFY--------------CDRPWQRA 300 C+CNGHA C D +C+ T G +C RC Y C P Sbjct: 867 CQCNGHADDC--DPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPD 924 Query: 301 TARE-SHAC--------LACSCN-----------------------GHARRCRFNMELYR 328 + R+ + +C LAC C+ G + C+ + + Sbjct: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDT 984 Query: 329 LSGR---RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT 385 + G CL C ++T G HC +CR G+Y D + ++ CR C C+ +G + Sbjct: 985 TDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDCRKCVCNYLGTVQEH 1039 Query: 386 CN-------QTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA--PC 421 CN + TGQC C V G C+RCAP Q S PC Sbjct: 1040 CNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPC 1084 Score = 71.6 bits (174), Expect = 2e-12 Identities = 59/217 (27%), Positives = 78/217 (35%), Gaps = 57/217 (26%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C G C RC P + P +C C CNGHA C Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDCD-----------P 878 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ- 392 G CLNC+ T G +C C G+Y DP D CR C C +G+ ++ Q Sbjct: 879 VTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDH--CRPCPCPDGPDSGRQFARSCYQD 936 Query: 393 -------CPCKDGVTGLTCNRCAPGFQQSRSPVA----PCVKTPIPGPTEDSSPVQPQDC 441 C C G G C+ CA G+ + S V PC + P+ C Sbjct: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC------QCHNNIDTTDPEAC 990 Query: 442 D---------------SHCKPAR-GSYRISLKKFCKK 462 D HC+ R G Y +L++ C+K Sbjct: 991 DKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRK 1027 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/103 (35%), Positives = 44/103 (42%), Gaps = 11/103 (10%) Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393 +GG C CR N GR C+ C PG C+ C+CH G+ CN TGQC Sbjct: 788 NGGQC-QCRPNVVGRTCNRCA------PGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQC 840 Query: 394 PCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPV 436 C GV C+RC PG S C G +D PV Sbjct: 841 HCFQGVYARQCDRCLPGHWGFPS----CQPCQCNGHADDCDPV 879 Score = 56.2 bits (134), Expect = 8e-08 Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 12/91 (13%) Query: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPC---------- 421 AC+C P G+ C+ GQC C+ V G TCNRCAPG F S PC Sbjct: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNA 831 Query: 422 VKTPIPGPTEDSSPVQPQDCDSHCKPARGSY 452 P+ G V + CD C P + Sbjct: 832 FCNPVTGQCHCFQGVYARQCD-RCLPGHWGF 861 Score = 30.8 bits (68), Expect = 3.6 Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 19/90 (21%) Query: 270 GHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN-GHARRCRFNMELYR 328 GH C C+ G C +C P + W + + C C C+ G A N + Sbjct: 477 GH--CYCKRLVTGQHCDQCLPEH----W--GLSNDLDGCRPCDCDLGGA----LNNSCFA 524 Query: 329 LSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 SG+ S CR + GR C+ G+Y Sbjct: 525 ESGQCS------CRPHMIGRQCNEVEPGYY 548 >gi|62868217 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 196 bits (498), Expect = 5e-50 Identities = 127/414 (30%), Positives = 196/414 (47%), Gaps = 45/414 (10%) Query: 31 HDEGGAPRG-CVPGLVNAALGRE--VLASSTCG--RPATRA------------CDASDPR 73 H + RG C P + + +GR + ASSTCG +P T CD+ P Sbjct: 16 HAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQMKCCKCDSRQPH 75 Query: 74 RAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133 +S + + ++ P+ W P V+L + L + F+L V + F PA + Sbjct: 76 NYYSHRV-ENVASSSGPMRWWQSQNDVNP--VSLQLDLDRRFQLQEVMMEFQGPMPAGML 132 Query: 134 LLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDG---SGL 190 + +S D G++W + ++ C + R+ G + C P +P+ G Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRV---RQGRPQSWQDVRCQSLP-QRPNARLNGGK 188 Query: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYS--YAATD 248 + ++ D G+ S +Q+ T++RV TR + P P S YA + Sbjct: 189 VQLNLMDLVS-GIPATQSQKIQEVGEITNLRVNFTRLA----PVPQRGYHPPSAYYAVSQ 243 Query: 249 LQVGGRCKCNGHASRCL----------LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298 L++ G C C+GHA RC Q H +C C+H T GP+C RC PFY +RPW+ Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303 Query: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 A +++H C C CNGH+ C F+ ++ S GGVC NCR +T G++C C+ ++ Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 359 RDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 R+ S + C +C+C P GA G C+ TGQC CK+ V G C+ C PGF Sbjct: 364 RNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417 Score = 75.1 bits (183), Expect = 2e-13 Identities = 59/213 (27%), Positives = 79/213 (37%), Gaps = 70/213 (32%) Query: 254 RCKCNGHASRCLLD------TQGHL--ICD-CRHGTEGPDCGRCKPFYCDRPWQRATARE 304 RC CNGH+ C D +QG +CD CR TEG +C RC+ Y A+ +E Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374 Query: 305 SHACLACSCNGHA-------------------------------------------RRCR 321 + C++C C+ RC Sbjct: 375 T--CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCD 432 Query: 322 FNMELYRLSGRRS------GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375 N+ L RR G CL C N G C C ++ L+ + C C Sbjct: 433 CNI----LGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK-----LASGQGCEPCA 482 Query: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408 C P + CNQ TGQCPC++G GL C+ A Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515 Score = 70.5 bits (171), Expect = 4e-12 Identities = 51/183 (27%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306 RC CN +L ++ + CD C GP C +C P++ W+ A+ + Sbjct: 430 RCDCN------ILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQ--- 476 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366 C C+C+ H + + + +G+ CR G C + P R Sbjct: 477 GCEPCACDPHNS---LSPQCNQFTGQ------CPCREGFGGLMCSAA--AIRQCPDRTYG 525 Query: 367 D-RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA----PC 421 D CRACDC G G C++ +G+C C+ G+TG C++C G+ +R PV PC Sbjct: 526 DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584 Query: 422 VKT 424 +T Sbjct: 585 FQT 587 Score = 57.4 bits (137), Expect = 4e-08 Identities = 42/152 (27%), Positives = 60/152 (39%), Gaps = 26/152 (17%) Query: 310 ACSCNGHARRC--RFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS- 366 +C C+GHA RC + + + VC+ C+HNTAG +C C + P R Sbjct: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEG 307 Query: 367 -DRRACRACDCH---------------PVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 D C+ CDC+ GA G C+ C+D G C RC Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLH 361 Query: 411 FQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCD 442 + ++R P A +T I + V CD Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPCD 393 >gi|62868215 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 196 bits (498), Expect = 5e-50 Identities = 127/414 (30%), Positives = 196/414 (47%), Gaps = 45/414 (10%) Query: 31 HDEGGAPRG-CVPGLVNAALGRE--VLASSTCG--RPATRA------------CDASDPR 73 H + RG C P + + +GR + ASSTCG +P T CD+ P Sbjct: 16 HAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQMKCCKCDSRQPH 75 Query: 74 RAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133 +S + + ++ P+ W P V+L + L + F+L V + F PA + Sbjct: 76 NYYSHRV-ENVASSSGPMRWWQSQNDVNP--VSLQLDLDRRFQLQEVMMEFQGPMPAGML 132 Query: 134 LLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDG---SGL 190 + +S D G++W + ++ C + R+ G + C P +P+ G Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRV---RQGRPQSWQDVRCQSLP-QRPNARLNGGK 188 Query: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYS--YAATD 248 + ++ D G+ S +Q+ T++RV TR + P P S YA + Sbjct: 189 VQLNLMDLVS-GIPATQSQKIQEVGEITNLRVNFTRLA----PVPQRGYHPPSAYYAVSQ 243 Query: 249 LQVGGRCKCNGHASRCL----------LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298 L++ G C C+GHA RC Q H +C C+H T GP+C RC PFY +RPW+ Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303 Query: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 A +++H C C CNGH+ C F+ ++ S GGVC NCR +T G++C C+ ++ Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 359 RDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 R+ S + C +C+C P GA G C+ TGQC CK+ V G C+ C PGF Sbjct: 364 RNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417 Score = 75.1 bits (183), Expect = 2e-13 Identities = 59/213 (27%), Positives = 79/213 (37%), Gaps = 70/213 (32%) Query: 254 RCKCNGHASRCLLD------TQGHL--ICD-CRHGTEGPDCGRCKPFYCDRPWQRATARE 304 RC CNGH+ C D +QG +CD CR TEG +C RC+ Y A+ +E Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374 Query: 305 SHACLACSCNGHA-------------------------------------------RRCR 321 + C++C C+ RC Sbjct: 375 T--CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCD 432 Query: 322 FNMELYRLSGRRS------GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375 N+ L RR G CL C N G C C ++ L+ + C C Sbjct: 433 CNI----LGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK-----LASGQGCEPCA 482 Query: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408 C P + CNQ TGQCPC++G GL C+ A Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515 Score = 70.5 bits (171), Expect = 4e-12 Identities = 51/183 (27%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306 RC CN +L ++ + CD C GP C +C P++ W+ A+ + Sbjct: 430 RCDCN------ILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQ--- 476 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366 C C+C+ H + + + +G+ CR G C + P R Sbjct: 477 GCEPCACDPHNS---LSPQCNQFTGQ------CPCREGFGGLMCSAA--AIRQCPDRTYG 525 Query: 367 D-RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA----PC 421 D CRACDC G G C++ +G+C C+ G+TG C++C G+ +R PV PC Sbjct: 526 DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584 Query: 422 VKT 424 +T Sbjct: 585 FQT 587 Score = 57.4 bits (137), Expect = 4e-08 Identities = 42/152 (27%), Positives = 60/152 (39%), Gaps = 26/152 (17%) Query: 310 ACSCNGHARRC--RFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS- 366 +C C+GHA RC + + + VC+ C+HNTAG +C C + P R Sbjct: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEG 307 Query: 367 -DRRACRACDCH---------------PVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 D C+ CDC+ GA G C+ C+D G C RC Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLH 361 Query: 411 FQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCD 442 + ++R P A +T I + V CD Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPCD 393 >gi|189083719 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 196 bits (498), Expect = 5e-50 Identities = 127/414 (30%), Positives = 196/414 (47%), Gaps = 45/414 (10%) Query: 31 HDEGGAPRG-CVPGLVNAALGRE--VLASSTCG--RPATRA------------CDASDPR 73 H + RG C P + + +GR + ASSTCG +P T CD+ P Sbjct: 16 HAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQMKCCKCDSRQPH 75 Query: 74 RAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133 +S + + ++ P+ W P V+L + L + F+L V + F PA + Sbjct: 76 NYYSHRV-ENVASSSGPMRWWQSQNDVNP--VSLQLDLDRRFQLQEVMMEFQGPMPAGML 132 Query: 134 LLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDG---SGL 190 + +S D G++W + ++ C + R+ G + C P +P+ G Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRV---RQGRPQSWQDVRCQSLP-QRPNARLNGGK 188 Query: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYS--YAATD 248 + ++ D G+ S +Q+ T++RV TR + P P S YA + Sbjct: 189 VQLNLMDLVS-GIPATQSQKIQEVGEITNLRVNFTRLA----PVPQRGYHPPSAYYAVSQ 243 Query: 249 LQVGGRCKCNGHASRCL----------LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298 L++ G C C+GHA RC Q H +C C+H T GP+C RC PFY +RPW+ Sbjct: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303 Query: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 A +++H C C CNGH+ C F+ ++ S GGVC NCR +T G++C C+ ++ Sbjct: 304 PAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 359 RDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 R+ S + C +C+C P GA G C+ TGQC CK+ V G C+ C PGF Sbjct: 364 RNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417 Score = 75.1 bits (183), Expect = 2e-13 Identities = 59/213 (27%), Positives = 79/213 (37%), Gaps = 70/213 (32%) Query: 254 RCKCNGHASRCLLD------TQGHL--ICD-CRHGTEGPDCGRCKPFYCDRPWQRATARE 304 RC CNGH+ C D +QG +CD CR TEG +C RC+ Y A+ +E Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374 Query: 305 SHACLACSCNGHA-------------------------------------------RRCR 321 + C++C C+ RC Sbjct: 375 T--CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCD 432 Query: 322 FNMELYRLSGRRS------GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375 N+ L RR G CL C N G C C ++ L+ + C C Sbjct: 433 CNI----LGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWK-----LASGQGCEPCA 482 Query: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408 C P + CNQ TGQCPC++G GL C+ A Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515 Score = 70.5 bits (171), Expect = 4e-12 Identities = 51/183 (27%), Positives = 80/183 (43%), Gaps = 37/183 (20%) Query: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306 RC CN +L ++ + CD C GP C +C P++ W+ A+ + Sbjct: 430 RCDCN------ILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQ--- 476 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366 C C+C+ H + + + +G+ CR G C + P R Sbjct: 477 GCEPCACDPHNS---LSPQCNQFTGQ------CPCREGFGGLMCSAA--AIRQCPDRTYG 525 Query: 367 D-RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA----PC 421 D CRACDC G G C++ +G+C C+ G+TG C++C G+ +R PV PC Sbjct: 526 DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584 Query: 422 VKT 424 +T Sbjct: 585 FQT 587 Score = 57.4 bits (137), Expect = 4e-08 Identities = 42/152 (27%), Positives = 60/152 (39%), Gaps = 26/152 (17%) Query: 310 ACSCNGHARRC--RFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS- 366 +C C+GHA RC + + + VC+ C+HNTAG +C C + P R Sbjct: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEG 307 Query: 367 -DRRACRACDCH---------------PVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 D C+ CDC+ GA G C+ C+D G C RC Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLH 361 Query: 411 FQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCD 442 + ++R P A +T I + V CD Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPCD 393 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 195 bits (496), Expect = 8e-50 Identities = 132/419 (31%), Positives = 198/419 (47%), Gaps = 48/419 (11%) Query: 67 CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRF 124 C++ DPR+AH P G S W+S L V LT+ LG+ F + ++ ++F Sbjct: 105 CNSEDPRKAH-PVTNAIDG---SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160 Query: 125 CSAP-PASVALLKSQDHGRSWAPLGFFSSH---CDLDYGRLPAPANGPAGPGPEALCFPA 180 ++P P L +S D G +++P +F+ C ++GR AN + LC Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGR---EANMAVTRDDDVLCVTE 217 Query: 181 -PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPST------AGDP 233 P +G + S+ + P + S L+++ AT++R+ R +T + Sbjct: 218 YSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQ 277 Query: 234 RDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLI-CDCRHGTEGPDCGRCKPFY 292 RD Y Y+ D+ +GG+C CNGHA C ++ L C+C+H T G C RC Y Sbjct: 278 RDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY 337 Query: 293 CDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR-------RSGGVCLNCRHNT 345 R W+ A +SH C AC+C+GHA C ++ ++ R GGVC+NC+HNT Sbjct: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397 Query: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405 AG +C C +G+YR G + C C C P A G C Q +G+C CK G C Sbjct: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCE 455 Query: 406 RCAPGFQQ----SRSPVAPCVKTP---------IPGPTEDSSPVQPQDCDSH----CKP 447 +CA G+ R P+ P V TP I G + V P+ CD+H C+P Sbjct: 456 KCAIGYYNFPFCLRIPIFP-VSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRP 513 Score = 103 bits (257), Expect = 4e-22 Identities = 67/192 (34%), Positives = 85/192 (44%), Gaps = 41/192 (21%) Query: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 IC C G C C P Y T R C+ C+CNGH+ +C+ Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVG--AAGKTCNQTT 390 G+C+NC+HNTAG HC C+EG+Y G A+ +CRAC C A G N Sbjct: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752 Query: 391 GQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKT---------PIPG-----PTED 432 +C CK G TG C RCAPG+ Q+ PC P+ G +D Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812 Query: 433 SSPVQP-QDCDS 443 SSP + DCDS Sbjct: 1813 SSPAEECDDCDS 1824 Score = 76.3 bits (186), Expect = 7e-14 Identities = 53/163 (32%), Positives = 68/163 (41%), Gaps = 23/163 (14%) Query: 255 CKCNG-HASRCLLDTQGHLICDCRHGTEGPDCGRCK------PFYCDRPWQRATARESHA 307 C C+ HA C QG C C+ G +C +C PF P + S Sbjct: 426 CSCDPEHADGC---EQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482 Query: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 +A G + C N+E + G CL CR G C CR GFY P Sbjct: 483 PVA----GDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFP------ 531 Query: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 C+AC C +G+ C+ TGQC C+ GVTG C+RC G Sbjct: 532 --ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572 Score = 66.2 bits (160), Expect = 8e-11 Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 30/159 (18%) Query: 257 CNGHASRCLLDTQGHL-----ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 C G +S C D G + C C+ EGP C RCK Y W S C C Sbjct: 579 CQGSSSAC--DPAGTINSNLGYCQCKLHVEGPTCSRCKLLY----WNLDKENPS-GCSEC 631 Query: 312 SCNGHARRCRFNMELYRLSG----RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 C+ + +SG R+ G C +C+ + G C C +G++ S+ Sbjct: 632 KCH----------KAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF---ALEKSN 677 Query: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNR 406 C+ C C GA C+ +G C C++ V G C R Sbjct: 678 YFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716 Score = 66.2 bits (160), Expect = 8e-11 Identities = 55/198 (27%), Positives = 77/198 (38%), Gaps = 30/198 (15%) Query: 217 ATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRC---KCNGHASRCLLDTQGHLI 273 A V + P+ AGD + P Y GRC CNGH+++C G I Sbjct: 1648 ALAVEICACPPAYAGD--SCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGI 1702 Query: 274 C-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 C +C+H T G C RC+ Y + A AC N A C N Sbjct: 1703 CVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHTNSFATGCVVN--------- 1749 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392 G V +C+ G C C G++ +P + +C+ C C+ G G +C+ TG Sbjct: 1750 -GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQPCSCNSNGQLG-SCHPLTGD 1804 Query: 393 C---PCKDGVTGLTCNRC 407 C KD C+ C Sbjct: 1805 CINQEPKDSSPAEECDDC 1822 Score = 63.2 bits (152), Expect = 6e-10 Identities = 51/176 (28%), Positives = 66/176 (37%), Gaps = 33/176 (18%) Query: 252 GGRCKC--NGHASRCLLDTQGHL------ICDCRHGTEGPDCGRCK-PFYCDRPWQRATA 302 GG+C C N +C GH C C G+C+ P RP + Sbjct: 1282 GGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRP--QCEV 1339 Query: 303 RESHA--------CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCR 354 E+H+ C C+C+ R +E R G C C+ GR C C Sbjct: 1340 CETHSFSFHPMAGCEGCNCSR-----RGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCA 1393 Query: 355 EGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 GFYR P C C+C+ G C+ TG C CK+ V G CN C G Sbjct: 1394 SGFYRFP--------ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREG 1441 Score = 55.5 bits (132), Expect = 1e-07 Identities = 54/186 (29%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 248 DLQVGGRCKCNGHASRCLLDTQGHLICDCRH-GTEGPDCGR------CKPFYCDRPWQR- 299 D Q R N S +G L C+C G GP C C+P R R Sbjct: 1240 DPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRC 1299 Query: 300 ATARESHA-CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 AT C CSC R C G C C T C C + Sbjct: 1300 ATGHYGFPRCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF 1345 Query: 359 RDPGRALSDRRACRACDCHPVG---AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSR 415 + C C+C G AA C++ +GQC CK +TG C+RCA GF + Sbjct: 1346 -----SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400 Query: 416 SPVAPC 421 V PC Sbjct: 1401 ECV-PC 1405 Score = 54.7 bits (130), Expect = 2e-07 Identities = 51/218 (23%), Positives = 70/218 (32%), Gaps = 64/218 (29%) Query: 239 VVPYSYAATDLQVGGRCK-CNGHASRCLLDT-QGHLICDCRHGTEGPDCGRCKPFYCDRP 296 + P S +++ V G K C+ + L + H C CR G EGP C C+ + P Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP 531 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREG 356 C AC C+ + Y++ G C CR G+ C C G Sbjct: 532 ----------ICQACWCSA--------LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSG 572 Query: 357 FYR-----------DPGRALSDR------------------------------RACRACD 375 Y DP ++ C C Sbjct: 573 AYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632 Query: 376 CHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAPGF 411 CH G T C Q G C CK V G +C+ C G+ Sbjct: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 36/113 (31%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C+ G C RC + P C+ C+CN G Sbjct: 1378 CRCKPRITGRQCDRCASGFYRFP----------ECVPCNCNR--------------DGTE 1413 Query: 334 SG------GVCLNCRHNTAGRHCHYCREG-FYRDPGRALSDRRACRACDCHPV 379 G G CL C+ N G C+ CREG F+ DP ++ + C +C C V Sbjct: 1414 PGVCDPGTGACL-CKENVEGTECNVCREGSFHLDP----ANLKGCTSCFCFGV 1461 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 195 bits (496), Expect = 8e-50 Identities = 132/419 (31%), Positives = 198/419 (47%), Gaps = 48/419 (11%) Query: 67 CDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRF 124 C++ DPR+AH P G S W+S L V LT+ LG+ F + ++ ++F Sbjct: 105 CNSEDPRKAH-PVTNAIDG---SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160 Query: 125 CSAP-PASVALLKSQDHGRSWAPLGFFSSH---CDLDYGRLPAPANGPAGPGPEALCFPA 180 ++P P L +S D G +++P +F+ C ++GR AN + LC Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGR---EANMAVTRDDDVLCVTE 217 Query: 181 -PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPST------AGDP 233 P +G + S+ + P + S L+++ AT++R+ R +T + Sbjct: 218 YSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQ 277 Query: 234 RDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLI-CDCRHGTEGPDCGRCKPFY 292 RD Y Y+ D+ +GG+C CNGHA C ++ L C+C+H T G C RC Y Sbjct: 278 RDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY 337 Query: 293 CDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR-------RSGGVCLNCRHNT 345 R W+ A +SH C AC+C+GHA C ++ ++ R GGVC+NC+HNT Sbjct: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397 Query: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405 AG +C C +G+YR G + C C C P A G C Q +G+C CK G C Sbjct: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCE 455 Query: 406 RCAPGFQQ----SRSPVAPCVKTP---------IPGPTEDSSPVQPQDCDSH----CKP 447 +CA G+ R P+ P V TP I G + V P+ CD+H C+P Sbjct: 456 KCAIGYYNFPFCLRIPIFP-VSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRP 513 Score = 103 bits (257), Expect = 4e-22 Identities = 67/192 (34%), Positives = 85/192 (44%), Gaps = 41/192 (21%) Query: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 IC C G C C P Y T R C+ C+CNGH+ +C+ Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVG--AAGKTCNQTT 390 G+C+NC+HNTAG HC C+EG+Y G A+ +CRAC C A G N Sbjct: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752 Query: 391 GQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKT---------PIPG-----PTED 432 +C CK G TG C RCAPG+ Q+ PC P+ G +D Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812 Query: 433 SSPVQP-QDCDS 443 SSP + DCDS Sbjct: 1813 SSPAEECDDCDS 1824 Score = 76.3 bits (186), Expect = 7e-14 Identities = 53/163 (32%), Positives = 68/163 (41%), Gaps = 23/163 (14%) Query: 255 CKCNG-HASRCLLDTQGHLICDCRHGTEGPDCGRCK------PFYCDRPWQRATARESHA 307 C C+ HA C QG C C+ G +C +C PF P + S Sbjct: 426 CSCDPEHADGC---EQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482 Query: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 +A G + C N+E + G CL CR G C CR GFY P Sbjct: 483 PVA----GDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFP------ 531 Query: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 C+AC C +G+ C+ TGQC C+ GVTG C+RC G Sbjct: 532 --ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572 Score = 66.2 bits (160), Expect = 8e-11 Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 30/159 (18%) Query: 257 CNGHASRCLLDTQGHL-----ICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 C G +S C D G + C C+ EGP C RCK Y W S C C Sbjct: 579 CQGSSSAC--DPAGTINSNLGYCQCKLHVEGPTCSRCKLLY----WNLDKENPS-GCSEC 631 Query: 312 SCNGHARRCRFNMELYRLSG----RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 C+ + +SG R+ G C +C+ + G C C +G++ S+ Sbjct: 632 KCH----------KAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF---ALEKSN 677 Query: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNR 406 C+ C C GA C+ +G C C++ V G C R Sbjct: 678 YFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR 716 Score = 66.2 bits (160), Expect = 8e-11 Identities = 55/198 (27%), Positives = 77/198 (38%), Gaps = 30/198 (15%) Query: 217 ATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRC---KCNGHASRCLLDTQGHLI 273 A V + P+ AGD + P Y GRC CNGH+++C G I Sbjct: 1648 ALAVEICACPPAYAGD--SCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGI 1702 Query: 274 C-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 C +C+H T G C RC+ Y + A AC N A C N Sbjct: 1703 CVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHTNSFATGCVVN--------- 1749 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392 G V +C+ G C C G++ +P + +C+ C C+ G G +C+ TG Sbjct: 1750 -GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQPCSCNSNGQLG-SCHPLTGD 1804 Query: 393 C---PCKDGVTGLTCNRC 407 C KD C+ C Sbjct: 1805 CINQEPKDSSPAEECDDC 1822 Score = 63.2 bits (152), Expect = 6e-10 Identities = 51/176 (28%), Positives = 66/176 (37%), Gaps = 33/176 (18%) Query: 252 GGRCKC--NGHASRCLLDTQGHL------ICDCRHGTEGPDCGRCK-PFYCDRPWQRATA 302 GG+C C N +C GH C C G+C+ P RP + Sbjct: 1282 GGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRP--QCEV 1339 Query: 303 RESHA--------CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCR 354 E+H+ C C+C+ R +E R G C C+ GR C C Sbjct: 1340 CETHSFSFHPMAGCEGCNCSR-----RGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCA 1393 Query: 355 EGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410 GFYR P C C+C+ G C+ TG C CK+ V G CN C G Sbjct: 1394 SGFYRFP--------ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREG 1441 Score = 55.5 bits (132), Expect = 1e-07 Identities = 54/186 (29%), Positives = 66/186 (35%), Gaps = 32/186 (17%) Query: 248 DLQVGGRCKCNGHASRCLLDTQGHLICDCRH-GTEGPDCGR------CKPFYCDRPWQR- 299 D Q R N S +G L C+C G GP C C+P R R Sbjct: 1240 DPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRC 1299 Query: 300 ATARESHA-CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358 AT C CSC R C G C C T C C + Sbjct: 1300 ATGHYGFPRCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF 1345 Query: 359 RDPGRALSDRRACRACDCHPVG---AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSR 415 + C C+C G AA C++ +GQC CK +TG C+RCA GF + Sbjct: 1346 -----SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400 Query: 416 SPVAPC 421 V PC Sbjct: 1401 ECV-PC 1405 Score = 54.7 bits (130), Expect = 2e-07 Identities = 51/218 (23%), Positives = 70/218 (32%), Gaps = 64/218 (29%) Query: 239 VVPYSYAATDLQVGGRCK-CNGHASRCLLDT-QGHLICDCRHGTEGPDCGRCKPFYCDRP 296 + P S +++ V G K C+ + L + H C CR G EGP C C+ + P Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP 531 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREG 356 C AC C+ + Y++ G C CR G+ C C G Sbjct: 532 ----------ICQACWCSA--------LGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSG 572 Query: 357 FYR-----------DPGRALSDR------------------------------RACRACD 375 Y DP ++ C C Sbjct: 573 AYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECK 632 Query: 376 CHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAPGF 411 CH G T C Q G C CK V G +C+ C G+ Sbjct: 633 CHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGY 670 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 36/113 (31%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C+ G C RC + P C+ C+CN G Sbjct: 1378 CRCKPRITGRQCDRCASGFYRFP----------ECVPCNCNR--------------DGTE 1413 Query: 334 SG------GVCLNCRHNTAGRHCHYCREG-FYRDPGRALSDRRACRACDCHPV 379 G G CL C+ N G C+ CREG F+ DP ++ + C +C C V Sbjct: 1414 PGVCDPGTGACL-CKENVEGTECNVCREGSFHLDP----ANLKGCTSCFCFGV 1461 >gi|190014607 netrin G2 [Homo sapiens] Length = 530 Score = 194 bits (494), Expect = 1e-49 Identities = 123/393 (31%), Positives = 186/393 (47%), Gaps = 50/393 (12%) Query: 58 TCGRPATR------------ACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103 TCG P R CDAS+P AH P L+ W+S + R +PL Sbjct: 60 TCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPL 119 Query: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 +T+ K EL V + F P + L KS D+GR+W P F++ C +G Sbjct: 120 EANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSA 179 Query: 163 APANGPAGPGPEALCFPAPLAQPDGSGL---LAFSMQDS----SPPGL--------DLDS 207 A + + ++ GS + F ++D + P L L+S Sbjct: 180 RRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLES 239 Query: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267 + L+++ T TD+R+ L RP+ G E + Y YA ++++V GRCKCN HA+ C + Sbjct: 240 AKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSM- 298 Query: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT-----ARESHACLA------CSCNGH 316 +G L C+C H T GPDCG+CK + R W+ + +AC C C GH Sbjct: 299 REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGH 358 Query: 317 ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC 376 + RC + L ++ C++C+HNT G+HC +CR G+YR+ L D C C+C Sbjct: 359 SNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411 Query: 377 HPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 + +G+ CN+ TG C C++G G C+ C P Sbjct: 412 NQIGSVHDRCNE-TGFCECREGAAGPKCDDCLP 443 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 193 bits (490), Expect = 4e-49 Identities = 142/482 (29%), Positives = 205/482 (42%), Gaps = 77/482 (15%) Query: 10 LTAGTLFAALSPGPPAP----------ADPCHDEGGAPRGCVPGLVNAALGREVLASSTC 59 L AG+ P PAP A +E G P N A G + AS+TC Sbjct: 5 LCAGSALCVRGPRGPAPLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATC 64 Query: 60 GRPATRA----------------------------------CDASDPRRAHSPALLTSPG 85 G A C A++ +AH PA G Sbjct: 65 GEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAH-PASNAIDG 123 Query: 86 GTASPLCWRSESLPRAPL--NVTLTVPLGKAFELVFVSLRFCSAP-PASVALLKSQDHGR 142 + W+S L R V +T+ LG+ F + +V ++F ++P P L +S D GR Sbjct: 124 ---TERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGR 180 Query: 143 SWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA-PLAQPDGSGLLAFSMQDSSPP 201 ++ P FF+S R A+C P +G + S+ + P Sbjct: 181 TYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPG 240 Query: 202 GLDLDSSPVLQDWVTATDVRVVLTRPST------AGDPRDMEAVVPYSYAATDLQVGGRC 255 ++ SP+L+++ AT+VR+ R +T RD Y Y+ D+ +GGRC Sbjct: 241 AMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRC 300 Query: 256 KCNGHASRCLLDTQG-----HLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLA 310 C+GHA C D + L C C+H T G C RC P + +PW+ ATA ++ C + Sbjct: 301 VCHGHADAC--DAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358 Query: 311 CSCNGHARRCRFNMELYRLSGRRS-------GGVCLNCRHNTAGRHCHYCREGFYRDPGR 363 C+C GHA C ++ E+ R +S GGVC++C+H+T G +C C GFYR P Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418 Query: 364 ALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVK 423 L CR C+C G TC TG+C C+ +G C+ CA GF S C Sbjct: 419 PLDSPHVCRRCNCESDFTDG-TCEDLTGRCYCRPNFSGERCDVCAEGFTGFPS----CYP 473 Query: 424 TP 425 TP Sbjct: 474 TP 475 Score = 90.5 bits (223), Expect = 4e-18 Identities = 61/192 (31%), Positives = 77/192 (40%), Gaps = 23/192 (11%) Query: 258 NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHA 317 N A C+L G C C+ G G C RC P + P + +C C C+G+ Sbjct: 1922 NNFAEGCVL-RGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGS-----SCQPCDCSGNG 1975 Query: 318 RRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH 377 + L+ G C C +T G C C GFY G AL C CDC Sbjct: 1976 DPNLLFSDCDPLT-----GACRGCLRHTTGPRCEICAPGFY---GNALLPGN-CTRCDCT 2026 Query: 378 PVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF--QQSRSPVAPCVKTPIPGPTEDSSP 435 P G + C+ +G C CK GVTG C+RC G PC GP + S Sbjct: 2027 PCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCA----CGPAAEGSE 2080 Query: 436 VQPQDCDSHCKP 447 PQ HC+P Sbjct: 2081 CHPQSGQCHCRP 2092 Score = 84.0 bits (206), Expect = 4e-16 Identities = 64/193 (33%), Positives = 79/193 (40%), Gaps = 34/193 (17%) Query: 273 ICDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSG 331 +C C G C C P FY D C+ C C+GH+ RC L G Sbjct: 1830 LCLCPASYRGDSCQECAPGFYRD-----VKGLFLGRCVPCQCHGHSDRC--------LPG 1876 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFY--RDPGRALSDRRACRACDCH---PVGAAGKTC 386 GVC++C+HNT G HC C+ GF RD A C +C C P + C Sbjct: 1877 ---SGVCVDCQHNTEGAHCERCQAGFVSSRDDPSA-----PCVSCPCPLSVPSNNFAEGC 1928 Query: 387 NQTTG--QCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444 G QC CK G G +C RCAPGF + P V P + S P S Sbjct: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGN-----PLVLGSSCQPCDCSGNGDPNLLFSD 1983 Query: 445 CKPARGSYRISLK 457 C P G+ R L+ Sbjct: 1984 CDPLTGACRGCLR 1996 Score = 81.6 bits (200), Expect = 2e-15 Identities = 62/203 (30%), Positives = 78/203 (38%), Gaps = 44/203 (21%) Query: 252 GGRCKCNGHA-----SRCLLDTQGH----------LICD-------CRHGTEGPDCGRCK 289 GG+C C+ H SRC G +CD C T PDC C+ Sbjct: 1454 GGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513 Query: 290 PFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRH 349 P Q C C+C+G + EL + G C CR N GR Sbjct: 1514 P-------QTFGCHPLVGCEECNCSGPGIQ-----ELTDPTCDTDSGQC-KCRPNVTGRR 1560 Query: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 C C GF+ P CR CDCH G A C+ TGQC CK+ V G C++C+ Sbjct: 1561 CDTCSPGFHGYP--------RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612 Query: 410 G-FQQSRSPVAPCVKTPIPGPTE 431 G F + C + G TE Sbjct: 1613 GTFSLDAANPKGCTRCFCFGATE 1635 Score = 79.7 bits (195), Expect = 7e-15 Identities = 57/170 (33%), Positives = 67/170 (39%), Gaps = 36/170 (21%) Query: 255 CKCNGHA---SRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 C+C+ RC DT C CR G EG C RC P Y P C C Sbjct: 541 CQCSSPGVADDRCDPDTGQ---CRCRVGFEGATCDRCAPGYFHFP----------LCQLC 587 Query: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371 C+ G G CL C+ AG HC CR G++ P C Sbjct: 588 GCSPAGTLPE---------GCDEAGRCL-CQPEFAGPHCDRCRPGYHGFPN--------C 629 Query: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421 +AC C P GA + C G C C+ G TG C C+PGF S V PC Sbjct: 630 QACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFPSCV-PC 677 Score = 78.6 bits (192), Expect = 1e-14 Identities = 71/275 (25%), Positives = 89/275 (32%), Gaps = 87/275 (31%) Query: 255 CKCNGHASRCLLDT---------------QGHLIC-DCRHGTEGPDCGRCKP-FY----- 292 C C GHA+ C D QG +C DC+H T G +C RC P FY Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418 Query: 293 ------------CDRPWQRATARESHACLACSCNGHARRCRFNMELYR------------ 328 C+ + T + C N RC E + Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478 Query: 329 -------------------LSGRRSG--------GVCLNCRHNTAGRHCHYCREGFYRDP 361 +G + G CL C+ N G HC C GFY P Sbjct: 479 NDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFY-GP 536 Query: 362 GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ----SRSP 417 G C+ C C G A C+ TGQC C+ G G TC+RCAPG+ Sbjct: 537 G--------CQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCG 588 Query: 418 VAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSY 452 +P P QP+ HC R Y Sbjct: 589 CSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGY 623 Score = 74.7 bits (182), Expect = 2e-13 Identities = 45/137 (32%), Positives = 59/137 (43%), Gaps = 28/137 (20%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C+ GP C RC+P Y P C AC+C+ L +L G Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------LDQLCG-- 645 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393 +GG+C CR G C C GF+ P +C C C G+ C+ +GQC Sbjct: 646 AGGLC-RCRPGYTGTACQECSPGFHGFP--------SCVPCHCSAEGSLHAACDPRSGQC 696 Query: 394 PCKDGVTGLTCNRCAPG 410 C+ VTGL C+ C PG Sbjct: 697 SCRPRVTGLRCDTCVPG 713 Score = 73.2 bits (178), Expect = 6e-13 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 25/140 (17%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN-----GHARRCRFNMELYR 328 C CR EGP C RCKP + W + + C CSC+ G C+ Sbjct: 744 CMCRAHVEGPSCDRCKPGF----WGLSPSNPE-GCTRCSCDLRGTLGGVAECQ------- 791 Query: 329 LSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQ 388 G C C+ + G+ C C++GF+ G +D CR+C C GA G++C Sbjct: 792 ----PGTGQCF-CKPHVCGQACASCKDGFF---GLDQADYFGCRSCRCDIGGALGQSCEP 843 Query: 389 TTGQCPCKDGVTGLTCNRCA 408 TG C C+ G TC+ A Sbjct: 844 RTGVCRCRPNTQGPTCSEPA 863 Score = 55.1 bits (131), Expect = 2e-07 Identities = 51/204 (25%), Positives = 67/204 (32%), Gaps = 52/204 (25%) Query: 254 RCKCNGHA----SRCLLDTQGHL--------ICDCRHGTEGPDCGRCKPFYCDRPWQRAT 301 RC+ H C D +G L +C CR G G C C P + P Sbjct: 618 RCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPC 677 Query: 302 ARESHACLACSCNGHARRCRFNMELYRLSGRR--------------SGGVC--------- 338 + L +C+ + +C R++G R G C Sbjct: 678 HCSAEGSLHAACDPRSGQCSCRP---RVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVD 734 Query: 339 ---------LNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT--CN 387 CR + G C C+ GF+ G + S+ C C C G G C Sbjct: 735 PALPEAQVPCMCRAHVEGPSCDRCKPGFW---GLSPSNPEGCTRCSCDLRGTLGGVAECQ 791 Query: 388 QTTGQCPCKDGVTGLTCNRCAPGF 411 TGQC CK V G C C GF Sbjct: 792 PGTGQCFCKPHVCGQACASCKDGF 815 Score = 54.7 bits (130), Expect = 2e-07 Identities = 26/57 (45%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 357 FYRDPGRALS--DRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 F R+ +LS R C CH VGA G TC GQCPC V G C+RCA G+ Sbjct: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY 1475 Score = 31.6 bits (70), Expect = 2.1 Identities = 16/50 (32%), Positives = 19/50 (38%), Gaps = 9/50 (18%) Query: 274 CDCRHGTEGPDCGRCK--PFYCDRPWQRATARESHACLACSCNGHARRCR 321 C C+ +GP C +C F D A C C C G RCR Sbjct: 1596 CYCKENVQGPKCDQCSLGTFSLD-------AANPKGCTRCFCFGATERCR 1638 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 190 bits (483), Expect = 3e-48 Identities = 141/486 (29%), Positives = 219/486 (45%), Gaps = 76/486 (15%) Query: 38 RGCVPGLVNAALGREVLASSTCGR--------------------PATRACD--ASDPRRA 75 RG P ++N A + ++TCG P R CD +++PR Sbjct: 20 RGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRER 79 Query: 76 HSPALLTSPGGTASPLCWRSESLP--RAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133 H + + GT + W+S S+ R VT+T+ L + F++ +V ++ +AP Sbjct: 80 HP--ISHAIDGTNN--WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNW 135 Query: 134 LLKSQDHGRSWAPLGFFS---SHCDLDYGRLPAPANGPAGPGPEALC--FPAPLAQPDGS 188 +L+ G +++P +++ S C Y P E +C + + L P Sbjct: 136 ILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLV-PLEH 194 Query: 189 GLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAG---------DPRDMEAV 239 G + S+ + P DL SP L ++ +A +R+ L R T +P++++ + Sbjct: 195 GEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPI 252 Query: 240 VP--YSYAATDLQVGGRCKCNGHASRCLLD-TQGHLICDCRHGTEGPDCGRCKPFYCDRP 296 V Y Y+ D+ VGG C C GHAS C D T L C C H T G C RC P Y +P Sbjct: 253 VTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQP 312 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYR------LSGR-RSGGVCLNCRHNTAGRH 349 W+ T + C AC+C+ A+ C ++ + + +G+ R GGVC+NC NT G + Sbjct: 313 WRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372 Query: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTC-----------NQTTGQCPCKDG 398 C C +G+YR + + CR C+C PVG+ C + GQCPCK+G Sbjct: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432 Query: 399 VTGLTCNRCAPGFQQ-------SRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGS 451 TG C+RC G++ +PV P GP V+ + CD CKP G Sbjct: 433 YTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD-RCKP--GF 489 Query: 452 YRISLK 457 Y + K Sbjct: 490 YNLKEK 495 Score = 94.4 bits (233), Expect = 3e-19 Identities = 61/195 (31%), Positives = 80/195 (41%), Gaps = 26/195 (13%) Query: 258 NGHASRCLLDTQGHLICD-CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGH 316 N + C L+ ++CD C G G C RC Y P +C+ C C+G+ Sbjct: 800 NNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP-----TVPGESCVPCDCSGN 854 Query: 317 ARRCRFNMELYRLSGRRSG--GVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 +G G CL C NT G HC C +GFY D A + CRAC Sbjct: 855 VDPSE--------AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTA----KNCRAC 902 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQ--QSRSPVAPCVKTPIPGPTED 432 +CH G+ C+ TG C CK VTG C++C G+ S PC + G D Sbjct: 903 ECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPC-NCSVAGSVSD 961 Query: 433 SSPVQPQDCDSHCKP 447 + Q HC P Sbjct: 962 GCTDEGQ---CHCVP 973 Score = 80.5 bits (197), Expect = 4e-15 Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 25/189 (13%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C+C G G C C Y ++ C C C+GHA C + Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393 GVC+ C HNT G HC C GFY +P R C+ C C P+ A + T C Sbjct: 755 --GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPG--DCQPCAC-PLTIASNNFSPT---C 806 Query: 394 PCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYR 453 DG + C+ CAPG+ S + C PT P DC + P+ + Sbjct: 807 HLNDG-DEVVCDWCAPGY--SGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHC 863 Query: 454 ISLKKFCKK 462 S+ C K Sbjct: 864 DSVTGECLK 872 Score = 77.4 bits (189), Expect = 3e-14 Identities = 47/155 (30%), Positives = 68/155 (43%), Gaps = 13/155 (8%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314 C CN H+ C D +C T G C C Y + + T S C C+C Sbjct: 1403 CSCNNHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGY----YGKVTGSASD-CALCACP 1455 Query: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 H+ F+ L G C C G+HC C +Y +P + +C+ C Sbjct: 1456 -HSPPASFSPTCV-LEGDHDFR-CDACLLGYEGKHCERCSSSYYGNPQ---TPGGSCQKC 1509 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 DC+P G+ C++T+GQC C+ G +GL C+ C P Sbjct: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544 Score = 59.7 bits (143), Expect = 7e-09 Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 28/149 (18%) Query: 274 CDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332 C C G G C RC FY A + +C C C C Sbjct: 969 CHCVPGVAGKRCDRCAHGFY---------AYQDGSCTPCDCPHTQNTCD----------- 1008 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392 G C+ C +T G C C +G + C+AC+C VG+ C+ TG Sbjct: 1009 PETGECV-CPPHTQGVKCEECEDGHWGYDAEV-----GCQACNCSLVGSTHHRCDVVTGH 1062 Query: 393 CPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421 C CK G C++C+ G++ V PC Sbjct: 1063 CQCKSKFGGRACDQCSLGYRDFPDCV-PC 1090 Score = 55.5 bits (132), Expect = 1e-07 Identities = 46/161 (28%), Positives = 54/161 (33%), Gaps = 47/161 (29%) Query: 274 CDCRH--GTEGPDCGRCKPFYCDRPWQRATARESH----------ACLACSCN---GHAR 318 CDC H T P+ G C C Q E C AC+C+ Sbjct: 998 CDCPHTQNTCDPETGEC---VCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHH 1054 Query: 319 RCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHP 378 RC G C C+ GR C C G+ P C CDC Sbjct: 1055 RCDVVT-----------GHC-QCKSKFGGRACDQCSLGYRDFPD--------CVPCDCDL 1094 Query: 379 VGAAGKTCN---------QTTGQCPCKDGVTGLTCNRCAPG 410 G +G CN + TG CPCK+ V G CN C G Sbjct: 1095 RGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREG 1135 Score = 37.7 bits (86), Expect = 0.029 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 8/61 (13%) Query: 393 CPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH---CKPAR 449 C C G G +C CAPG+ + + P GP +P P C++H C P Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAG-----SDRGPRPLVAPCVPCSCNNHSDTCDPNT 1416 Query: 450 G 450 G Sbjct: 1417 G 1417 Score = 35.8 bits (81), Expect = 0.11 Identities = 37/134 (27%), Positives = 50/134 (37%), Gaps = 22/134 (16%) Query: 248 DLQVGGR-CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATAR 303 D +VG + C C+ S RC + T GH C C+ G C +C Y D P Sbjct: 1036 DAEVGCQACNCSLVGSTHHRCDVVT-GH--CQCKSKFGGRACDQCSLGYRDFP------- 1085 Query: 304 ESHACLACSCNGHARRC-RFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPG 362 C+ C C+ N+E G C C+ N G C+ CREG + Sbjct: 1086 ---DCVPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTF---A 1138 Query: 363 RALSDRRACRACDC 376 + C C C Sbjct: 1139 LRADNPLGCSPCFC 1152 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 167 bits (424), Expect = 2e-41 Identities = 130/473 (27%), Positives = 204/473 (43%), Gaps = 72/473 (15%) Query: 38 RGCVPGLVNAALGREVLASSTCGR--------------------PATRACD--ASDPRRA 75 RG P ++N A + ++TCG P R C+ +S+P + Sbjct: 37 RGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQR 96 Query: 76 HSPALLTSPGGTASPLCWRSESLPRAPLN--VTLTVPLGKAFELVFVSLRFCSAP-PASV 132 H T W+S S+ VT+T+ L + F++ +V ++ ++P P + Sbjct: 97 HPITNAIDGKNT----WWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNW 152 Query: 133 ALLKSQD--HGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALC--FPAPLAQPDGS 188 L +S D + W + C Y P E +C F + + P + Sbjct: 153 ILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI-HPLEN 211 Query: 189 GLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAG---------DPRDMEAV 239 G + S+ + P D SP L ++ +A +R+ R T DPR+++ + Sbjct: 212 GEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPI 269 Query: 240 VP--YSYAATDLQVGGRCKCNGHASRCLLDTQGHLI-CDCRHGTEGPDCGRCKPFYCDRP 296 V Y Y+ D+ VGG C C GHA C LD + C+C H T G C +C P + +P Sbjct: 270 VTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKP 329 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYR------LSGRR-SGGVCLNCRHNTAGRH 349 W+ T C AC+C+G A C ++ + R + G+ GGVC+NC NTAG + Sbjct: 330 WRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389 Query: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTC---------NQTTGQCPCKDGVT 400 C C +GF+R G + + R C+ C C P+G+ + C G C CK G Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449 Query: 401 GLTCNRCAPGFQQ-------SRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCK 446 G++C+RCA G+ + S + + P GP V+ DC S CK Sbjct: 450 GVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDC-SRCK 501 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/169 (31%), Positives = 76/169 (44%), Gaps = 22/169 (13%) Query: 258 NGHASRCLLDTQGHLICD-CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGH 316 N + C LD LICD C G GP C RC Y +P + +C C CN Sbjct: 816 NNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP-----SVPGGSCQPCQCND- 869 Query: 317 ARRCRFNMELYRLSGRRSG--GVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 N++ + + G G CL C+ T GR+C C +G++ D D + C+ C Sbjct: 870 ------NLD-FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA----VDAKNCQPC 918 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF--QQSRSPVAPC 421 C+ G+ + C+ TGQC C+ V G C++C G QS PC Sbjct: 919 RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPC 967 Score = 78.6 bits (192), Expect = 1e-14 Identities = 55/184 (29%), Positives = 77/184 (41%), Gaps = 28/184 (15%) Query: 237 EAVVPYSYAATDLQVGGR-----------CKCNGHASRCLLDTQGHLICDCRHGTEGPDC 285 EA +P Y Q GGR C+CNGH+S C D + + +C+H T G C Sbjct: 1392 EACLPGFYRLRS-QPGGRTPGPTLGTCVPCQCNGHSSLC--DPETSICQNCQHHTAGDFC 1448 Query: 286 GRCKPFYCDRPWQRATARESHAC-LACSCNGHARRC-RFNMELYRLSGRRSGGVCLNCRH 343 RC Y + AC L S N + C ++ YR C C Sbjct: 1449 ERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR---------CTACPR 1499 Query: 344 NTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLT 403 G++C C G+ PG + +C+ C+C P G+ C+ TG C C+ G TG Sbjct: 1500 GYEGQYCERCAPGYTGSPG---NPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556 Query: 404 CNRC 407 C+ C Sbjct: 1557 CDGC 1560 Score = 69.7 bits (169), Expect = 7e-12 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 24/151 (15%) Query: 274 CDCRHGTEGPDCGRCKP-FYCDR--PWQRATARESHACLACSCNGHARRCRFNMELYRLS 330 CDC G G C C P FY R P R C+ C CNGH+ C Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--------- 1430 Query: 331 GRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTT 390 +C NC+H+TAG C C G+Y G C+ C C + ++ Sbjct: 1431 --PETSICQNCQHHTAGDFCERCALGYY---GIVKGLPNDCQQCACPLISSSNNFSPSCV 1485 Query: 391 GQ-------CPCKDGVTGLTCNRCAPGFQQS 414 + C G G C RCAPG+ S Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTGS 1516 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 30/188 (15%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314 C CN S+ D + C C+ G G C RC Y + + C AC C+ Sbjct: 967 CNCNSFGSKSF-DCEESGQCWCQPGVTGKKCDRCAHGYFNF--------QEGGCTACECS 1017 Query: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 C G C+ C NT G C C + G +++ C+AC Sbjct: 1018 HLGNNCD-----------PKTGRCI-CPPNTIGEKCSKCAPNTW---GHSITT--GCKAC 1060 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDS 433 +C VG+ CN TGQC C +G C C+ G + R + C +PG + Sbjct: 1061 NCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCF---LPGTDATT 1117 Query: 434 SPVQPQDC 441 + + C Sbjct: 1118 CDSETKKC 1125 Score = 65.5 bits (158), Expect = 1e-10 Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 38/191 (19%) Query: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARE-SHACLACSCNGHARRCRFNMELYRLSG 331 +C C G G C C P + +R C C C GHA C Sbjct: 723 VCQCPPGYTGSSCESCWPRH-----RRVNGTIFGGICEPCQCFGHAESCD---------- 767 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTC-- 386 G CLNC+ +T G +C C GFY +P + S+ C+ C C P TC Sbjct: 768 -DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSE--DCQPCACPLNIPSNNFSPTCHL 824 Query: 387 NQTTGQC--PCKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDSSPVQ-PQDCD 442 +++ G C G TG C RCA G F Q P C P D+ P CD Sbjct: 825 DRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQ----PCQCNDNLDFSIPGSCD 880 Query: 443 S------HCKP 447 S CKP Sbjct: 881 SLSGSCLICKP 891 Score = 63.9 bits (154), Expect = 4e-10 Identities = 48/174 (27%), Positives = 61/174 (35%), Gaps = 38/174 (21%) Query: 248 DLQVGG--RCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARES 305 + Q GG C+C+ + C T C C T G C +C P W + Sbjct: 1005 NFQEGGCTACECSHLGNNCDPKTGR---CICPPNTIGEKCSKCAP----NTWGHSITTGC 1057 Query: 306 HACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRAL 365 AC + +C N G C NC +G C C G + P Sbjct: 1058 KACNCSTVGSLDFQCNVNT-----------GQC-NCHPKFSGAKCTECSRGHWNYP---- 1101 Query: 366 SDRRACRACDCHPVGAAGKTCNQTT---------GQCPCKDGVTGLTCNRCAPG 410 C CDC G TC+ T GQC CK V G+ C+RC PG Sbjct: 1102 ----RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151 Score = 38.5 bits (88), Expect = 0.017 Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 24/119 (20%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C+ G G C RC Y P C AC+C+G + + Sbjct: 442 CHCKTGFGGVSCDRCARGYTGYP----------DCKACNCSGLGSK----------NEDP 481 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392 G C+ C+ N G C C+ GF+ + + C C C V ++ T G+ Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFF---NLQEDNWKGCDECFCSGVSNRCQSSYWTYGK 536 Score = 37.4 bits (85), Expect = 0.038 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 392 QCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSS-PVQPQDCDSHCKPARG 450 +C C G +GL+C C PGF + RS P +T PGPT + P Q S C P Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS--QPGGRT--PGPTLGTCVPCQCNGHSSLCDP-ET 1433 Query: 451 SYRISLKKFCKKDYAVQVAVGARGEARG 478 S + + D+ + A+G G +G Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKG 1461 Score = 31.6 bits (70), Expect = 2.1 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 18/70 (25%) Query: 19 LSPGPPAPADPCH-------------DEGGAPRGCVPGLVNAALGREVLASSTCGR---- 61 +SP P P PCH DE A RG PG + G ++ C R Sbjct: 403 VSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG 462 Query: 62 -PATRACDAS 70 P +AC+ S Sbjct: 463 YPDCKACNCS 472 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 167 bits (424), Expect = 2e-41 Identities = 130/473 (27%), Positives = 204/473 (43%), Gaps = 72/473 (15%) Query: 38 RGCVPGLVNAALGREVLASSTCGR--------------------PATRACD--ASDPRRA 75 RG P ++N A + ++TCG P R C+ +S+P + Sbjct: 37 RGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQR 96 Query: 76 HSPALLTSPGGTASPLCWRSESLPRAPLN--VTLTVPLGKAFELVFVSLRFCSAP-PASV 132 H T W+S S+ VT+T+ L + F++ +V ++ ++P P + Sbjct: 97 HPITNAIDGKNT----WWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNW 152 Query: 133 ALLKSQD--HGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALC--FPAPLAQPDGS 188 L +S D + W + C Y P E +C F + + P + Sbjct: 153 ILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI-HPLEN 211 Query: 189 GLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAG---------DPRDMEAV 239 G + S+ + P D SP L ++ +A +R+ R T DPR+++ + Sbjct: 212 GEIHISLINGRPSADD--PSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPI 269 Query: 240 VP--YSYAATDLQVGGRCKCNGHASRCLLDTQGHLI-CDCRHGTEGPDCGRCKPFYCDRP 296 V Y Y+ D+ VGG C C GHA C LD + C+C H T G C +C P + +P Sbjct: 270 VTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKP 329 Query: 297 WQRATARESHACLACSCNGHARRCRFNMELYR------LSGRR-SGGVCLNCRHNTAGRH 349 W+ T C AC+C+G A C ++ + R + G+ GGVC+NC NTAG + Sbjct: 330 WRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389 Query: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTC---------NQTTGQCPCKDGVT 400 C C +GF+R G + + R C+ C C P+G+ + C G C CK G Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449 Query: 401 GLTCNRCAPGFQQ-------SRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCK 446 G++C+RCA G+ + S + + P GP V+ DC S CK Sbjct: 450 GVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDC-SRCK 501 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/169 (31%), Positives = 76/169 (44%), Gaps = 22/169 (13%) Query: 258 NGHASRCLLDTQGHLICD-CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGH 316 N + C LD LICD C G GP C RC Y +P + +C C CN Sbjct: 816 NNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP-----SVPGGSCQPCQCND- 869 Query: 317 ARRCRFNMELYRLSGRRSG--GVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 N++ + + G G CL C+ T GR+C C +G++ D D + C+ C Sbjct: 870 ------NLD-FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA----VDAKNCQPC 918 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF--QQSRSPVAPC 421 C+ G+ + C+ TGQC C+ V G C++C G QS PC Sbjct: 919 RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPC 967 Score = 78.6 bits (192), Expect = 1e-14 Identities = 55/184 (29%), Positives = 77/184 (41%), Gaps = 28/184 (15%) Query: 237 EAVVPYSYAATDLQVGGR-----------CKCNGHASRCLLDTQGHLICDCRHGTEGPDC 285 EA +P Y Q GGR C+CNGH+S C D + + +C+H T G C Sbjct: 1392 EACLPGFYRLRS-QPGGRTPGPTLGTCVPCQCNGHSSLC--DPETSICQNCQHHTAGDFC 1448 Query: 286 GRCKPFYCDRPWQRATARESHAC-LACSCNGHARRC-RFNMELYRLSGRRSGGVCLNCRH 343 RC Y + AC L S N + C ++ YR C C Sbjct: 1449 ERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR---------CTACPR 1499 Query: 344 NTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLT 403 G++C C G+ PG + +C+ C+C P G+ C+ TG C C+ G TG Sbjct: 1500 GYEGQYCERCAPGYTGSPG---NPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556 Query: 404 CNRC 407 C+ C Sbjct: 1557 CDGC 1560 Score = 69.7 bits (169), Expect = 7e-12 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 24/151 (15%) Query: 274 CDCRHGTEGPDCGRCKP-FYCDR--PWQRATARESHACLACSCNGHARRCRFNMELYRLS 330 CDC G G C C P FY R P R C+ C CNGH+ C Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--------- 1430 Query: 331 GRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTT 390 +C NC+H+TAG C C G+Y G C+ C C + ++ Sbjct: 1431 --PETSICQNCQHHTAGDFCERCALGYY---GIVKGLPNDCQQCACPLISSSNNFSPSCV 1485 Query: 391 GQ-------CPCKDGVTGLTCNRCAPGFQQS 414 + C G G C RCAPG+ S Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTGS 1516 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/188 (26%), Positives = 71/188 (37%), Gaps = 30/188 (15%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314 C CN S+ D + C C+ G G C RC Y + + C AC C+ Sbjct: 967 CNCNSFGSKSF-DCEESGQCWCQPGVTGKKCDRCAHGYFNF--------QEGGCTACECS 1017 Query: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374 C G C+ C NT G C C + G +++ C+AC Sbjct: 1018 HLGNNCD-----------PKTGRCI-CPPNTIGEKCSKCAPNTW---GHSITT--GCKAC 1060 Query: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDS 433 +C VG+ CN TGQC C +G C C+ G + R + C +PG + Sbjct: 1061 NCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCF---LPGTDATT 1117 Query: 434 SPVQPQDC 441 + + C Sbjct: 1118 CDSETKKC 1125 Score = 65.5 bits (158), Expect = 1e-10 Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 38/191 (19%) Query: 273 ICDCRHGTEGPDCGRCKPFYCDRPWQRATARE-SHACLACSCNGHARRCRFNMELYRLSG 331 +C C G G C C P + +R C C C GHA C Sbjct: 723 VCQCPPGYTGSSCESCWPRH-----RRVNGTIFGGICEPCQCFGHAESCD---------- 767 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTC-- 386 G CLNC+ +T G +C C GFY +P + S+ C+ C C P TC Sbjct: 768 -DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSE--DCQPCACPLNIPSNNFSPTCHL 824 Query: 387 NQTTGQC--PCKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDSSPVQ-PQDCD 442 +++ G C G TG C RCA G F Q P C P D+ P CD Sbjct: 825 DRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQ----PCQCNDNLDFSIPGSCD 880 Query: 443 S------HCKP 447 S CKP Sbjct: 881 SLSGSCLICKP 891 Score = 63.9 bits (154), Expect = 4e-10 Identities = 48/174 (27%), Positives = 61/174 (35%), Gaps = 38/174 (21%) Query: 248 DLQVGG--RCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARES 305 + Q GG C+C+ + C T C C T G C +C P W + Sbjct: 1005 NFQEGGCTACECSHLGNNCDPKTGR---CICPPNTIGEKCSKCAP----NTWGHSITTGC 1057 Query: 306 HACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRAL 365 AC + +C N G C NC +G C C G + P Sbjct: 1058 KACNCSTVGSLDFQCNVNT-----------GQC-NCHPKFSGAKCTECSRGHWNYP---- 1101 Query: 366 SDRRACRACDCHPVGAAGKTCNQTT---------GQCPCKDGVTGLTCNRCAPG 410 C CDC G TC+ T GQC CK V G+ C+RC PG Sbjct: 1102 ----RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151 Score = 38.5 bits (88), Expect = 0.017 Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 24/119 (20%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C+ G G C RC Y P C AC+C+G + + Sbjct: 442 CHCKTGFGGVSCDRCARGYTGYP----------DCKACNCSGLGSK----------NEDP 481 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392 G C+ C+ N G C C+ GF+ + + C C C V ++ T G+ Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFF---NLQEDNWKGCDECFCSGVSNRCQSSYWTYGK 536 Score = 37.4 bits (85), Expect = 0.038 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 392 QCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSS-PVQPQDCDSHCKPARG 450 +C C G +GL+C C PGF + RS P +T PGPT + P Q S C P Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRS--QPGGRT--PGPTLGTCVPCQCNGHSSLCDP-ET 1433 Query: 451 SYRISLKKFCKKDYAVQVAVGARGEARG 478 S + + D+ + A+G G +G Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKG 1461 Score = 31.6 bits (70), Expect = 2.1 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 18/70 (25%) Query: 19 LSPGPPAPADPCH-------------DEGGAPRGCVPGLVNAALGREVLASSTCGR---- 61 +SP P P PCH DE A RG PG + G ++ C R Sbjct: 403 VSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG 462 Query: 62 -PATRACDAS 70 P +AC+ S Sbjct: 463 YPDCKACNCS 472 >gi|219842266 usherin isoform B [Homo sapiens] Length = 5202 Score = 163 bits (412), Expect = 5e-40 Identities = 97/321 (30%), Positives = 151/321 (47%), Gaps = 23/321 (7%) Query: 105 VTLTVPLGKA-FELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPA 163 VT++V L +++ ++ ++F S P + + + +++ W +F+ +C G Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC----GAFGM 424 Query: 164 PANGPAGPGPEALCFPAPLAQPDGSGLLAFSMQDSSP---PGLD-LDSSPVLQDWVTATD 219 NG C P G + FS+ P PG + ++P LQ++V AT Sbjct: 425 KNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 Query: 220 VRVVLTRPSTAGDPRDMEAVVPYS---YAATDLQVGGRCKCNGHASRCLLDTQGH-LICD 275 +R G E V YA ++ + GRC+C+GHA C +Q + +C Sbjct: 485 IRFHFH-----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCS 539 Query: 276 CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSG---R 332 TEG C RC P Y D+P+++ + C C CN H++ C +N+ + R Sbjct: 540 QESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR 599 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT--CNQTT 390 GGVC +C HNT GR+C C++ F+R G S C+ CDC VG + C+Q Sbjct: 600 GGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIG 659 Query: 391 GQCPCKDGVTGLTCNRCAPGF 411 GQC CK V+G CN+C GF Sbjct: 660 GQCNCKRHVSGRQCNQCQNGF 680 Score = 77.4 bits (189), Expect = 3e-14 Identities = 52/165 (31%), Positives = 68/165 (41%), Gaps = 37/165 (22%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSC 313 C+CN H S C+C+ +G C C+ FY + C AC C Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY---------GLDVTNCKACDC 797 Query: 314 NGHARRCRFNMELYRLSGRRSGGVC------LNCRHNTAGRHCHYCREG-FYRDPGRALS 366 + +G G VC C+ N GR C+ C EG FY + Sbjct: 798 D--------------TAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF- 842 Query: 367 DRRACRACDCHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAP 409 C C+C G + CN++TGQCPCK GVTGL CN+C P Sbjct: 843 ---LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884 Score = 75.1 bits (183), Expect = 2e-13 Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 45/191 (23%) Query: 250 QVGGRCKCNGHAS-----RCL--------LDTQGHLICDCR-HGTEGPDC------GRCK 289 Q+GG+C C H S +C LD G C+C GT D G+CK Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716 Query: 290 PF---------YCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLN 340 +C+ ++ + C C CN H +F G C Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC--------NPHSGQC-E 767 Query: 341 CRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGV 399 C+ G C CRE FY D C+ACDC G+ G CN TGQC CK V Sbjct: 768 CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNV 821 Query: 400 TGLTCNRCAPG 410 G CN+C G Sbjct: 822 EGRQCNKCLEG 832 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 35/184 (19%) Query: 260 HASRCLLDTQGHL---ICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESHACL 309 H C D+ G L ICD C +G C +C+P + P CL Sbjct: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNAT------GCL 949 Query: 310 ACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCRE---GFYRDPGRALS 366 CSC+ N L+G+ C+ + AG+ C C++ GF GR Sbjct: 950 PCSCHTTGA---VNHICNSLTGQ-----CVCQDASIAGQRCDQCKDHYFGFDPQTGR--- 998 Query: 367 DRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVKTP 425 C+ C+CH GA +TC+ TGQC CK VTG C+ C P + + C KTP Sbjct: 999 ----CQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTP 1054 Query: 426 IPGP 429 P Sbjct: 1055 FQQP 1058 Score = 67.4 bits (163), Expect = 3e-11 Identities = 52/220 (23%), Positives = 76/220 (34%), Gaps = 73/220 (33%) Query: 255 CKCNGHASRCLLDTQ------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQRATA 302 C+CN H+ C + G + DC H T G +C CK ++ + +A Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634 Query: 303 RESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR--- 359 + C C C+ R + + GG C NC+ + +GR C+ C+ GFY Sbjct: 635 ID--VCKPCDCDTVGTRNG------SILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQE 685 Query: 360 -DPG-----------------------------------------------RALSDRRAC 371 DP R+ +D C Sbjct: 686 LDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDV-GC 744 Query: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 C C+ G+ K CN +GQC CK GL C+ C F Sbjct: 745 EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENF 784 >gi|219842259 usherin isoform A [Homo sapiens] Length = 1546 Score = 163 bits (412), Expect = 5e-40 Identities = 97/321 (30%), Positives = 151/321 (47%), Gaps = 23/321 (7%) Query: 105 VTLTVPLGKA-FELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPA 163 VT++V L +++ ++ ++F S P + + + +++ W +F+ +C G Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC----GAFGM 424 Query: 164 PANGPAGPGPEALCFPAPLAQPDGSGLLAFSMQDSSP---PGLD-LDSSPVLQDWVTATD 219 NG C P G + FS+ P PG + ++P LQ++V AT Sbjct: 425 KNNGDLEKPDSVNCLQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484 Query: 220 VRVVLTRPSTAGDPRDMEAVVPYS---YAATDLQVGGRCKCNGHASRCLLDTQGH-LICD 275 +R G E V YA ++ + GRC+C+GHA C +Q + +C Sbjct: 485 IRFHFH-----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCS 539 Query: 276 CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSG---R 332 TEG C RC P Y D+P+++ + C C CN H++ C +N+ + R Sbjct: 540 QESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR 599 Query: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT--CNQTT 390 GGVC +C HNT GR+C C++ F+R G S C+ CDC VG + C+Q Sbjct: 600 GGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIG 659 Query: 391 GQCPCKDGVTGLTCNRCAPGF 411 GQC CK V+G CN+C GF Sbjct: 660 GQCNCKRHVSGRQCNQCQNGF 680 Score = 77.4 bits (189), Expect = 3e-14 Identities = 52/165 (31%), Positives = 68/165 (41%), Gaps = 37/165 (22%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSC 313 C+CN H S C+C+ +G C C+ FY + C AC C Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY---------GLDVTNCKACDC 797 Query: 314 NGHARRCRFNMELYRLSGRRSGGVC------LNCRHNTAGRHCHYCREG-FYRDPGRALS 366 + +G G VC C+ N GR C+ C EG FY + Sbjct: 798 D--------------TAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF- 842 Query: 367 DRRACRACDCHPVGAAGKT--CNQTTGQCPCKDGVTGLTCNRCAP 409 C C+C G + CN++TGQCPCK GVTGL CN+C P Sbjct: 843 ---LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884 Score = 75.1 bits (183), Expect = 2e-13 Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 45/191 (23%) Query: 250 QVGGRCKCNGHAS-----RCL--------LDTQGHLICDCR-HGTEGPDC------GRCK 289 Q+GG+C C H S +C LD G C+C GT D G+CK Sbjct: 657 QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716 Query: 290 PF---------YCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLN 340 +C+ ++ + C C CN H +F G C Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC--------NPHSGQC-E 767 Query: 341 CRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGV 399 C+ G C CRE FY D C+ACDC G+ G CN TGQC CK V Sbjct: 768 CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNV 821 Query: 400 TGLTCNRCAPG 410 G CN+C G Sbjct: 822 EGRQCNKCLEG 832 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 35/184 (19%) Query: 260 HASRCLLDTQGHL---ICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESHACL 309 H C D+ G L ICD C +G C +C+P + P CL Sbjct: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNAT------GCL 949 Query: 310 ACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCRE---GFYRDPGRALS 366 CSC+ N L+G+ C+ + AG+ C C++ GF GR Sbjct: 950 PCSCHTTGA---VNHICNSLTGQ-----CVCQDASIAGQRCDQCKDHYFGFDPQTGR--- 998 Query: 367 DRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVKTP 425 C+ C+CH GA +TC+ TGQC CK VTG C+ C P + + C KTP Sbjct: 999 ----CQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTP 1054 Query: 426 IPGP 429 P Sbjct: 1055 FQQP 1058 Score = 67.4 bits (163), Expect = 3e-11 Identities = 52/220 (23%), Positives = 76/220 (34%), Gaps = 73/220 (33%) Query: 255 CKCNGHASRCLLDTQ------------GHLICDCRHGTEGPDCGRCKPFYCDRPWQRATA 302 C+CN H+ C + G + DC H T G +C CK ++ + +A Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634 Query: 303 RESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR--- 359 + C C C+ R + + GG C NC+ + +GR C+ C+ GFY Sbjct: 635 ID--VCKPCDCDTVGTRNG------SILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQE 685 Query: 360 -DPG-----------------------------------------------RALSDRRAC 371 DP R+ +D C Sbjct: 686 LDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDV-GC 744 Query: 372 RACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 C C+ G+ K CN +GQC CK GL C+ C F Sbjct: 745 EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENF 784 >gi|54312078 netrin G1 isoform 3 [Homo sapiens] Length = 438 Score = 124 bits (311), Expect = 2e-28 Identities = 103/361 (28%), Positives = 146/361 (40%), Gaps = 48/361 (13%) Query: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103 TCG P CDAS P AH P L+ G W+S + PL Sbjct: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130 Query: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD + Sbjct: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189 Query: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207 + E +C S ++ F ++D + P L LD+ Sbjct: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249 Query: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267 + L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D Sbjct: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309 Query: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELY 327 L C+C H T GPDCG+CK Y RPW + A +C N+ Sbjct: 310 -NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDN 368 Query: 328 RLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCN 387 L ++GG C HN C G C C G+ G Sbjct: 369 ELLHCQNGGTC----HNNVRCLCPAAYTGI------------LCEKLRCEEAGSCGSDSG 412 Query: 388 Q 388 Q Sbjct: 413 Q 413 Score = 32.0 bits (71), Expect = 1.6 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 12/124 (9%) Query: 364 ALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVK 423 A+SD + C C+ + A + + C C+ TG C +C +Q P +P Sbjct: 287 AISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSY 343 Query: 424 TPIPGPTEDS-----SPVQPQDCDS---HCKPARGSYRISLKKFCKKDYAVQVAVGARGE 475 PIP T ++ S + CD+ HC+ G+ +++ C Y + R E Sbjct: 344 LPIPKGTANTCIPSISSIGTNVCDNELLHCQNG-GTCHNNVRCLCPAAYTGILCEKLRCE 402 Query: 476 ARGA 479 G+ Sbjct: 403 EAGS 406 >gi|164414437 netrin G1 isoform 2 [Homo sapiens] Length = 480 Score = 123 bits (308), Expect = 5e-28 Identities = 87/270 (32%), Positives = 124/270 (45%), Gaps = 32/270 (11%) Query: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103 TCG P CDAS P AH P L+ G W+S + PL Sbjct: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130 Query: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD + Sbjct: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189 Query: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207 + E +C S ++ F ++D + P L LD+ Sbjct: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249 Query: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267 + L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D Sbjct: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309 Query: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPW 297 L C+C H T GPDCG+CK Y RPW Sbjct: 310 -NSKLTCECEHNTTGPDCGKCKKNYQGRPW 338 >gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] Length = 1111 Score = 105 bits (261), Expect = 1e-22 Identities = 64/179 (35%), Positives = 83/179 (46%), Gaps = 24/179 (13%) Query: 286 GRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNT 345 G C F P RAT+R C CNG +R+C F+ EL+R +G +G CLNC NT Sbjct: 7 GCCLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNT 60 Query: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405 G HC C+ GFYR +R C C+C+ G+ C+ +G+C CK GVTG C+ Sbjct: 61 DGIHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCD 114 Query: 406 RCAPGF-----------QQSRSPVAPCVKTPIPGPTEDSSPV-QPQDCDSHCKPARGSY 452 RC PGF Q+ C I GP + V +P C R Y Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGY 173 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/167 (31%), Positives = 68/167 (40%), Gaps = 31/167 (18%) Query: 255 CKCNGHASRCLLDTQ-------GHLICDCRHGTEGPDCGRCK-PFYCDRPWQRATARESH 306 C CNG + +C+ D + G +C T+G C +CK FY RE Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY--------RHRERD 79 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY--RDPGRA 364 CL C+CN LS R +C+ G C C GF+ D G Sbjct: 80 RCLPCNCNSKG----------SLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCT 129 Query: 365 LSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 R CDC P G AG C+ G+C CK VTG C+RC G+ Sbjct: 130 QDQRLLDSKCDCDPAGIAG-PCD--AGRCVCKPAVTGERCDRCRSGY 173 Score = 79.0 bits (193), Expect = 1e-14 Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Query: 255 CKC-NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPW-QRATARESHACLACS 312 C C NG + + +T+ + +C G G C C Y P+ + R C C Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRP---CQPCQ 518 Query: 313 CNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACR 372 CN + RL+GR CL C HNTAG +C C+ G++ DP A + CR Sbjct: 519 CNNNVDPSASG-NCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDP-LAPNPADKCR 571 Query: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408 AC+C+P+G+ C ++ G C CK G G C A Sbjct: 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEHGA 606 Score = 50.1 bits (118), Expect = 6e-06 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 48/184 (26%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESH--ACLACSCNGHARRCRFNMELYRLSG 331 C C G +G C C Y +R +AR C+ C+C G + Y SG Sbjct: 382 CICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQGGGACDPDTGDCY--SG 434 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTCNQ 388 + + C C GFY DP D R+C+ C CH +T Sbjct: 435 DENPDI-----------ECADCPIGFYNDP----HDPRSCKPCPCHNGFSCSVMPETEEV 479 Query: 389 TTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444 CP GVTG C CA G+ PV PC QP C+++ Sbjct: 480 VCNNCP--PGVTGARCELCADGYFGDPFGEHGPVRPC---------------QPCQCNNN 522 Query: 445 CKPA 448 P+ Sbjct: 523 VDPS 526 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 22/126 (17%) Query: 255 CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 C CN S RC D G C C+ G G C RC P + T + C Sbjct: 84 CNCNSKGSLSARC--DNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKC 139 Query: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371 C+ ++G G C+ C+ G C CR G+Y G + C Sbjct: 140 DCDPAG-----------IAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGC 184 Query: 372 RACDCH 377 C C+ Sbjct: 185 TQCFCY 190 Score = 32.7 bits (73), Expect = 0.94 Identities = 15/52 (28%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNME 325 C C+ G C RC+ Y + C C C GH+ CR + E Sbjct: 155 CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSASCRSSAE 201 >gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] Length = 1193 Score = 105 bits (261), Expect = 1e-22 Identities = 64/179 (35%), Positives = 83/179 (46%), Gaps = 24/179 (13%) Query: 286 GRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNT 345 G C F P RAT+R C CNG +R+C F+ EL+R +G +G CLNC NT Sbjct: 7 GCCLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNT 60 Query: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405 G HC C+ GFYR +R C C+C+ G+ C+ +G+C CK GVTG C+ Sbjct: 61 DGIHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCD 114 Query: 406 RCAPGF-----------QQSRSPVAPCVKTPIPGPTEDSSPV-QPQDCDSHCKPARGSY 452 RC PGF Q+ C I GP + V +P C R Y Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGY 173 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/167 (31%), Positives = 68/167 (40%), Gaps = 31/167 (18%) Query: 255 CKCNGHASRCLLDTQ-------GHLICDCRHGTEGPDCGRCK-PFYCDRPWQRATARESH 306 C CNG + +C+ D + G +C T+G C +CK FY RE Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY--------RHRERD 79 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY--RDPGRA 364 CL C+CN LS R +C+ G C C GF+ D G Sbjct: 80 RCLPCNCNSKG----------SLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCT 129 Query: 365 LSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411 R CDC P G AG C+ G+C CK VTG C+RC G+ Sbjct: 130 QDQRLLDSKCDCDPAGIAG-PCD--AGRCVCKPAVTGERCDRCRSGY 173 Score = 79.0 bits (193), Expect = 1e-14 Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Query: 255 CKC-NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPW-QRATARESHACLACS 312 C C NG + + +T+ + +C G G C C Y P+ + R C C Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRP---CQPCQ 518 Query: 313 CNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACR 372 CN + RL+GR CL C HNTAG +C C+ G++ DP A + CR Sbjct: 519 CNNNVDPSASG-NCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDP-LAPNPADKCR 571 Query: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408 AC+C+P+G+ C ++ G C CK G G C A Sbjct: 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEHGA 606 Score = 50.1 bits (118), Expect = 6e-06 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 48/184 (26%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESH--ACLACSCNGHARRCRFNMELYRLSG 331 C C G +G C C Y +R +AR C+ C+C G + Y SG Sbjct: 382 CICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQGGGACDPDTGDCY--SG 434 Query: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTCNQ 388 + + C C GFY DP D R+C+ C CH +T Sbjct: 435 DENPDI-----------ECADCPIGFYNDP----HDPRSCKPCPCHNGFSCSVMPETEEV 479 Query: 389 TTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444 CP GVTG C CA G+ PV PC QP C+++ Sbjct: 480 VCNNCP--PGVTGARCELCADGYFGDPFGEHGPVRPC---------------QPCQCNNN 522 Query: 445 CKPA 448 P+ Sbjct: 523 VDPS 526 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 22/126 (17%) Query: 255 CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311 C CN S RC D G C C+ G G C RC P + T + C Sbjct: 84 CNCNSKGSLSARC--DNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKC 139 Query: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371 C+ ++G G C+ C+ G C CR G+Y G + C Sbjct: 140 DCDPAG-----------IAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGC 184 Query: 372 RACDCH 377 C C+ Sbjct: 185 TQCFCY 190 Score = 32.7 bits (73), Expect = 0.94 Identities = 15/52 (28%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNME 325 C C+ G C RC+ Y + C C C GH+ CR + E Sbjct: 155 CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSASCRSSAE 201 >gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] Length = 1668 Score = 95.5 bits (236), Expect = 1e-19 Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 37/157 (23%) Query: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 C+ C+CNGH+ +C+ G+C+NC+HNTAG HC C+EG+Y G A+ Sbjct: 75 CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAGEHCERCQEGYY---GNAV-- 118 Query: 368 RRACRACDCHPVG--AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPC 421 +CRAC C A G N +C CK G TG C RCAPG+ Q+ PC Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178 Query: 422 VKT---------PIPG-----PTEDSSPVQP-QDCDS 443 P+ G +DSSP + DCDS Sbjct: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 25/157 (15%) Query: 255 CKCNGHASRCLLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC 313 C CNGH+++C G IC +C+H T G C RC+ Y + A AC Sbjct: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHT 130 Query: 314 NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRA 373 N A C N G V +C+ G C C G++ +P + +C+ Sbjct: 131 NSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQP 177 Query: 374 CDCHPVGAAGKTCNQTTGQC---PCKDGVTGLTCNRC 407 C C+ G G +C+ TG C KD C+ C Sbjct: 178 CSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213 >gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] Length = 1724 Score = 95.5 bits (236), Expect = 1e-19 Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 37/157 (23%) Query: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367 C+ C+CNGH+ +C+ G+C+NC+HNTAG HC C+EG+Y G A+ Sbjct: 75 CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAGEHCERCQEGYY---GNAV-- 118 Query: 368 RRACRACDCHPVG--AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPC 421 +CRAC C A G N +C CK G TG C RCAPG+ Q+ PC Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178 Query: 422 VKT---------PIPG-----PTEDSSPVQP-QDCDS 443 P+ G +DSSP + DCDS Sbjct: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 25/157 (15%) Query: 255 CKCNGHASRCLLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC 313 C CNGH+++C G IC +C+H T G C RC+ Y + A AC Sbjct: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHT 130 Query: 314 NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRA 373 N A C N G V +C+ G C C G++ +P + +C+ Sbjct: 131 NSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQP 177 Query: 374 CDCHPVGAAGKTCNQTTGQC---PCKDGVTGLTCNRC 407 C C+ G G +C+ TG C KD C+ C Sbjct: 178 CSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 90.5 bits (223), Expect = 4e-18 Identities = 56/169 (33%), Positives = 77/169 (45%), Gaps = 30/169 (17%) Query: 254 RCKCNGHASRCLLDTQGHLICD-CRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLAC 311 RC C+GH+ C +T C C+H TEGP C +C+P +Y D QR T ++ C C Sbjct: 1158 RCSCHGHSEACEPETGA---CQGCQHHTEGPRCEQCQPGYYGDA--QRGTPQD---CQLC 1209 Query: 312 SCNGH------ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRAL 365 C G A C + + C C +GRHC C G+Y +P + Sbjct: 1210 PCYGDPAAGQAAHTCFLDTD--------GHPTCDACSPGHSGRHCERCAPGYYGNPSQGQ 1261 Query: 366 SDRRACR-----ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 +R + C+C P G+ C+ GQC CK V GLTC+ C P Sbjct: 1262 PCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKAQVEGLTCSHCRP 1309 Score = 87.8 bits (216), Expect = 2e-17 Identities = 53/164 (32%), Positives = 70/164 (42%), Gaps = 25/164 (15%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C G GP C C Y P + C CSC+GH+ C Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEACE-----------P 1170 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK---TCNQTT 390 G C C+H+T G C C+ G+Y D R + C+ C C+ AAG+ TC T Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTP--QDCQLCPCYGDPAAGQAAHTCFLDT 1228 Query: 391 GQCP----CKDGVTGLTCNRCAPGFQQSRSPVAPCVK-TPIPGP 429 P C G +G C RCAPG+ + S PC + + +PGP Sbjct: 1229 DGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGP 1272 Score = 80.5 bits (197), Expect = 4e-15 Identities = 52/154 (33%), Positives = 69/154 (44%), Gaps = 26/154 (16%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C G G C C + P C C+CNGHA C +Y Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLG----TCSGCNCNGHASSCD---PVY------ 777 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK---TC-NQT 389 G CLNC+HNT G C+ C+ GF+ D +A + +CR C C + A+ + TC T Sbjct: 778 --GHCLNCQHNTEGPQCNKCKAGFFGDAMKATA--TSCRPCPCPYIDASRRFSDTCFLDT 833 Query: 390 TGQC---PCKDGVTGLTCNRCAPGFQQSRSPVAP 420 GQ C G TG C CAPG++ +P+ P Sbjct: 834 DGQATCDACAPGYTGRRCESCAPGYE--GNPIQP 865 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/145 (28%), Positives = 55/145 (37%), Gaps = 24/145 (16%) Query: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333 C C G G C C P Y + + C C CNGH+ C Sbjct: 1530 CRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLCH-----------P 1574 Query: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC---HPVGAAGKTCNQTT 390 G C C+HN AG C C G+Y D + C+ C C +P +TC Sbjct: 1575 ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPE--DCQPCACPLTNPENMFSRTCESLG 1632 Query: 391 G---QC-PCKDGVTGLTCNRCAPGF 411 +C C+ G TG C +C PG+ Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGY 1657 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/113 (28%), Positives = 43/113 (38%), Gaps = 20/113 (17%) Query: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC- 313 C+CNGH+ C +T C+H G C C P Y + ATA C C+C Sbjct: 1563 CECNGHSDLCHPETGA--CSQCQHNAAGEFCELCAPGY----YGDATAGTPEDCQPCACP 1616 Query: 314 -----NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDP 361 N +R C S G C C G++C C G+ +P Sbjct: 1617 LTNPENMFSRTCE--------SLGAGGYRCTACEPGYTGQYCEQCGPGYVGNP 1661 Score = 37.7 bits (86), Expect = 0.029 Identities = 31/128 (24%), Positives = 44/128 (34%), Gaps = 12/128 (9%) Query: 341 CRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCP-CKDGV 399 C G C C G+ R C C+C+ C+ TG C C+ Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGH--CELCECN---GHSDLCHPETGACSQCQHNA 1586 Query: 400 TGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKF 459 G C CAPG+ + P P P + + + C+S G YR + Sbjct: 1587 AGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCES---LGAGGYRCTA--- 1640 Query: 460 CKKDYAVQ 467 C+ Y Q Sbjct: 1641 CEPGYTGQ 1648 Score = 37.4 bits (85), Expect = 0.038 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 14/93 (15%) Query: 234 RDMEAVVPYSYAATDLQVGGRCK-CNGHASRCLLDTQGHL-----ICDCRHGTEGPDCGR 287 R E+ P Y +Q GG+C+ N RC D +G + C C++ G C Sbjct: 849 RRCESCAP-GYEGNPIQPGGKCRPVNQEIVRC--DERGSMGTSGEACRCKNNVVGRLCNE 905 Query: 288 CKPFYCDRPWQRATARESHACLACSCNGHARRC 320 C D + +T R CL C C G +R C Sbjct: 906 C----ADGSFHLST-RNPDGCLKCFCMGVSRHC 933 Score = 36.2 bits (82), Expect = 0.085 Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 14/78 (17%) Query: 248 DLQVGGRCKCN-----GHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATA 302 D QV G CN +S+C D G C C+ EG C C+P + +A Sbjct: 1266 DSQVPGPIGCNCDPQGSVSSQC--DAAGQ--CQCKAQVEGLTCSHCRPHHF-----HLSA 1316 Query: 303 RESHACLACSCNGHARRC 320 CL C C G ++C Sbjct: 1317 SNPDGCLPCFCMGITQQC 1334 Score = 31.6 bits (70), Expect = 2.1 Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 392 QCPCKDGVTGLTCNRCAPGFQQSRS 416 +C C G GL+C CAPG+ ++ S Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGS 1553 >gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] Length = 639 Score = 86.3 bits (212), Expect = 7e-17 Identities = 122/508 (24%), Positives = 167/508 (32%), Gaps = 128/508 (25%) Query: 9 LLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATRACD 68 LL AA + A A GGA G V+A+ G + + P A Sbjct: 12 LLCCAAAAAAAAVASAASAGNVTGGGGAA-----GQVDASPGPGLRGEPSHPFPRATAPT 66 Query: 69 ASDPRRA------HSPALLTSPGGT--ASPLCWRSESLPRAPLNVTLTVPLGKAFELVFV 120 A PR H P TSP + +PL W + P + T PLG + Sbjct: 67 AQAPRTGPPRATVHRPLAATSPAQSPETTPL-WATAG----PSSTTFQAPLGPS------ 115 Query: 121 SLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA 180 + PPA+ + AP ++ GPA P A PA Sbjct: 116 ----PTTPPAAERTSTTSQAPTRPAPTTLSTT-------------TGPAPTTPVATTVPA 158 Query: 181 PLAQPDGSGLLAFSMQDS---SPPGLDLDSSPVL-QDWVTATDVRVVLTRPSTAGDPRDM 236 P + L S S +PP + SSP W A + L + + + + Sbjct: 159 PTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSK 218 Query: 237 EAVVPYSYAATDLQVGGRCK----CNG------HASRCLLDTQGHLICDCRHGTEGPDCG 286 +P + +L+V K CN + +RC T G C+CR G +G C Sbjct: 219 --YLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCN-QTTGQ--CECRPGYQGLHCE 273 Query: 287 RCKP-FY---------------------------------------CDRPWQRATARESH 306 CK FY CDR + Sbjct: 274 TCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKN 333 Query: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366 CL C CN + C G CLNC+ N+ G HC C+EGFY+ P Sbjct: 334 GCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECKEGFYQSPDAT-- 380 Query: 367 DRRACRACDCHPVGAAGKTCNQTTGQCP----CKDGVTGLTCNRCAPGFQQSRSPVAPCV 422 + C C C V + G +++ P CKDG G CN+C G+ S C Sbjct: 381 --KECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKC- 437 Query: 423 KTPIPGPTEDSSPVQPQDCDSHCKPARG 450 + V P CKP G Sbjct: 438 --------QCHGHVDPVKTPKICKPESG 457 Score = 50.1 bits (118), Expect = 6e-06 Identities = 31/111 (27%), Positives = 44/111 (39%), Gaps = 18/111 (16%) Query: 254 RCKCNGHASRCLLDTQGHLI---CD-CRHGTEGPDCGRCKPFYCDRPWQRATARESHACL 309 RC C+ S + + CD C+ G GP+C +C+ Y + C Sbjct: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF---------DSICR 435 Query: 310 ACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRD 360 C C+GH + + G C+NC HNT G C C EG+ D Sbjct: 436 KCQCHGHVDPVKTPKIC-----KPESGECINCLHNTTGFWCENCLEGYVHD 481 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.468 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,727,764 Number of Sequences: 37866 Number of extensions: 1819057 Number of successful extensions: 11375 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 69 Number of HSP's successfully gapped in prelim test: 226 Number of HSP's that attempted gapping in prelim test: 9567 Number of HSP's gapped (non-prelim): 1246 length of query: 580 length of database: 18,247,518 effective HSP length: 108 effective length of query: 472 effective length of database: 14,157,990 effective search space: 6682571280 effective search space used: 6682571280 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.