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Search of human proteins with 5453557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453557 ariadne homolog 2 [Homo sapiens]
(493 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453557 ariadne homolog 2 [Homo sapiens] 1055 0.0
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 329 3e-90
gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 210 2e-54
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 177 2e-44
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 101 2e-21
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 101 2e-21
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 101 2e-21
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 101 2e-21
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 101 2e-21
gi|38045938 ring finger protein 144 [Homo sapiens] 101 2e-21
gi|50284696 IBR domain containing 2 [Homo sapiens] 97 4e-20
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 90 5e-18
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 89 7e-18
gi|35493801 ring finger protein 19 [Homo sapiens] 87 3e-17
gi|35493782 ring finger protein 19 [Homo sapiens] 87 3e-17
gi|169790973 parkin isoform 3 [Homo sapiens] 77 3e-14
gi|169790971 parkin isoform 2 [Homo sapiens] 77 3e-14
gi|169790969 parkin isoform 1 [Homo sapiens] 77 3e-14
gi|22749145 ring finger protein 217 [Homo sapiens] 69 7e-12
gi|109150431 ring finger protein 31 [Homo sapiens] 67 3e-11
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 62 2e-09
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 62 2e-09
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 54 3e-07
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 54 3e-07
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 40 0.005
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens] 39 0.008
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens] 39 0.008
gi|33636758 ring finger protein 146 [Homo sapiens] 39 0.014
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.031
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 37 0.041
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 1055 bits (2728), Expect = 0.0
Identities = 493/493 (100%), Positives = 493/493 (100%)
Query: 1 MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ 60
MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ
Sbjct: 1 MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ 60
Query: 61 FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA 120
FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA
Sbjct: 61 FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA 120
Query: 121 RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG 180
RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG
Sbjct: 121 RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG 180
Query: 181 VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ 240
VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ
Sbjct: 181 VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ 240
Query: 241 EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC 300
EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC
Sbjct: 241 EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC 300
Query: 301 NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE 360
NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE
Sbjct: 301 NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE 360
Query: 361 ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC 420
ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC
Sbjct: 361 ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC 420
Query: 421 RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE 480
RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE
Sbjct: 421 RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE 480
Query: 481 QRRRTLLKDFHDT 493
QRRRTLLKDFHDT
Sbjct: 481 QRRRTLLKDFHDT 493
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 329 bits (844), Expect = 3e-90
Identities = 178/537 (33%), Positives = 294/537 (54%), Gaps = 58/537 (10%)
Query: 11 DSNEE--DYDPNCEEEEEEEEDDP-------GDIEDYYVGVASDVEQQG----------A 51
D +EE + D EEEE+E++D+P G++E G+ E+ G
Sbjct: 12 DEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGG 71
Query: 52 DAFDP--------------------EEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVA 91
A P E+Y++ LT ++ + E + + V++ ++
Sbjct: 72 SALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATIT 131
Query: 92 KLILVNFHWQVSEILDRY-KSNSAQLLVEARVQPNPSKHVPT-------SHPPHHCAVCM 143
+++L +F+W ++++RY N +L E V NPSK T S C +C
Sbjct: 132 RILLSHFNWDKEKLMERYFDGNLEKLFAECHVI-NPSKKSRTRQMNTRSSAQDMPCQICY 190
Query: 144 QFVRKENLLSLACQHQFCRSCWEQHCSV-LVKDGVGVGVSCMAQDCPLRTPEDFVFPLLP 202
L C H+FC CW ++ + ++++G+G +SC A C + ++ V L+
Sbjct: 191 LNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLIT 250
Query: 203 NEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQ 262
+ +++ KY+ + +VE + L+ CP DC V++VQ P A+ V+C +C FCF C +
Sbjct: 251 DSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRC-KCGRQFCFNCGE 309
Query: 263 MYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQC--SKCKH 320
+H P C ++KW+ KC DDSET+N+I+A+TK+CPKC++ IEK+GGCNHM C CK
Sbjct: 310 NWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKA 369
Query: 321 DFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQ 380
+FCW+CLG W+ HGS +Y C+RY E+ + Q ++R AL++YLFY R+ NH +SL+
Sbjct: 370 EFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLR 429
Query: 381 LEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRK 440
E + Y ++ +K++E +N+ +WI+ Q+L+ A +L +CR TL YTY +A+Y++ +
Sbjct: 430 FEHKLYAQVKQKMEEMQQHNM-SWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQS 488
Query: 441 KLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDFHD 492
+FE QA LE E LS +ER S D + ++++ E RRR LL+ H+
Sbjct: 489 IIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHE 545
>gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo
sapiens]
Length = 1089
Score = 210 bits (535), Expect = 2e-54
Identities = 141/529 (26%), Positives = 245/529 (46%), Gaps = 92/529 (17%)
Query: 25 EEEEEDDPGDIED--YYVGVASDVEQQGADAFDPE----EYQFTCLTYKES-EGALNEHM 77
E E +D P D + ++ +A ++E Q + DPE E ++ L +E EG + +
Sbjct: 174 ENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDL 233
Query: 78 TSLASVLKVSHS--------VAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQ---PNP 126
L +L V + A+ +L W ++L+ + SN + VQ P P
Sbjct: 234 RRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPP 293
Query: 127 SKH-----VPTSHPPHH----------------------CAVCMQFVRK-ENLLSLACQH 158
S + +P+ P C +CM + E+ + + C H
Sbjct: 294 SGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGH 353
Query: 159 QFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDY 218
FCR CWE ++ +++G + C A DC P D + ++ ++E+ ++Y ++ + +
Sbjct: 354 DFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVV-SKEMDKRYLQFDIKAF 412
Query: 219 VESHYQLQLCPGADCPMVIRVQEP---------------RARRVQCNRCNEVFCFKCRQM 263
VE++ ++ CP C +R+ + RA V C + +FC++C
Sbjct: 413 VENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK-GHLFCWECLGE 471
Query: 264 YHAPTDCATIRKWLTKCAD--------------DSETANYISAHTKDCPKCNICIEKNGG 309
H P DC T + WL K + D+ ++ ++K C C I+KN G
Sbjct: 472 AHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEG 531
Query: 310 CNHMQCSKCKHDFCWMCLGDWKTHGSE---YYECSRYKENPDIVNQSQQAQAR------- 359
CNHMQC+KCK+DFCW+CL +WK H S YY C+RY+ + QS++
Sbjct: 532 CNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKR 591
Query: 360 -EALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE---RVMNNLGTWIDWQYLQNAAK 415
+ L +++ Y+ R++NH S QLE + + EK+++ + G D ++++A
Sbjct: 592 FQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVH 651
Query: 416 LLAKCRYTLQYTYPYAYYME-SGPRKKLFEYQQAQLEAEIENLSWKVER 463
+L K R L+ +YPY +++E +K++FE Q LE E+L+ KV R
Sbjct: 652 VLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNR 700
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 177 bits (449), Expect = 2e-44
Identities = 108/407 (26%), Positives = 181/407 (44%), Gaps = 33/407 (8%)
Query: 67 KESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNP 126
+E EG + + + + L + VA+ +L + HW ++L Y + LL+ A + +
Sbjct: 2000 QEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQ 2059
Query: 127 SKHVPTSHPPHHCAVCMQFVR-KENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMA 185
++ VP P HC VC+ + ++L SL C H C+SCW ++ + ++ + + +C
Sbjct: 2060 AQAVPVR--PDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPI 2117
Query: 186 QDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRAR 245
DCP + F+ ++ + E+ KY + L R YVES L C I ++
Sbjct: 2118 ADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGC 2177
Query: 246 RVQCNRCNEVFCFKCR-QMYHAPTDCATIRKWLTK------CADDSETANYISAHTKDCP 298
C++C CF C H P C + +W+ + ++++ + +K CP
Sbjct: 2178 GTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCP 2237
Query: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQA 358
C IEKN GC HM C+KC H FCW CL WK + +YY CS + ++A
Sbjct: 2238 SCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS-----------AMVSKA 2286
Query: 359 REALKKYLFYFERWENHNKSLQLEAQTYQR---IHEKIQERVMNNLGTWIDWQYLQNAAK 415
K++ Y ER H+++ + R IHE R + +L +A +
Sbjct: 2287 ARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPR---------SFTFLNDACQ 2337
Query: 416 LLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVE 462
L + R L Y Y++Y + + E Q LE L +E
Sbjct: 2338 GLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLE 2384
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 101 bits (251), Expect = 2e-21
Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C++C + + E + L C+H +C++C + + + ++DG ++C CP V
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
L+ EL +Y R L + ++ + CP C + + +QEP C+ CN FC
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 337
Query: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290
CR YH + C ++ + K ++ E+ ++
Sbjct: 338 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 397
Query: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
++K CP C IEK GCN M C+ C FCW+C+G
Sbjct: 398 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
D + A I C+IC + G M +C+H +C CL D+
Sbjct: 203 DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 250
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 101 bits (251), Expect = 2e-21
Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C++C + + E + L C+H +C++C + + + ++DG ++C CP V
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
L+ EL +Y R L + ++ + CP C + + +QEP C+ CN FC
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 337
Query: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290
CR YH + C ++ + K ++ E+ ++
Sbjct: 338 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 397
Query: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
++K CP C IEK GCN M C+ C FCW+C+G
Sbjct: 398 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
D + A I C+IC + G M +C+H +C CL D+
Sbjct: 203 DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 250
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 101 bits (251), Expect = 2e-21
Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C++C + + E + L C+H +C++C + + + ++DG ++C CP V
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
L+ EL +Y R L + ++ + CP C + + +QEP C+ CN FC
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 337
Query: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290
CR YH + C ++ + K ++ E+ ++
Sbjct: 338 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 397
Query: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
++K CP C IEK GCN M C+ C FCW+C+G
Sbjct: 398 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
D + A I C+IC + G M +C+H +C CL D+
Sbjct: 203 DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 250
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 101 bits (251), Expect = 2e-21
Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C++C + + E + L C+H +C++C + + + ++DG ++C CP V
Sbjct: 94 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
L+ EL +Y R L + ++ + CP C + + +QEP C+ CN FC
Sbjct: 154 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 211
Query: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290
CR YH + C ++ + K ++ E+ ++
Sbjct: 212 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 271
Query: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
++K CP C IEK GCN M C+ C FCW+C+G
Sbjct: 272 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 309
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
D + A I C+IC + G M +C+H +C CL D+
Sbjct: 77 DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 124
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 101 bits (251), Expect = 2e-21
Identities = 56/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 139 CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C++C + + E + L C+H +C++C + + + ++DG ++C CP V
Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC 257
L+ EL +Y R L + ++ + CP C + + +QEP C+ CN FC
Sbjct: 280 KELV-EAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPV-MQEPGCTMGICSSCNFAFC 337
Query: 258 FKCRQMYHAPTDCATI---------------------------RKWLTKCADDSETANYI 290
CR YH + C ++ + K ++ E+ ++
Sbjct: 338 TLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWL 397
Query: 291 SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
++K CP C IEK GCN M C+ C FCW+C+G
Sbjct: 398 EKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMG 435
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 283 DSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDW 330
D + A I C+IC + G M +C+H +C CL D+
Sbjct: 203 DFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDY 250
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 101 bits (251), Expect = 2e-21
Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 9/197 (4%)
Query: 139 CAVCMQFVRKENLLSLA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTP-EDF 196
C +C+ E + ++A CQ FC C +Q+ +L+K+G+ +SC CP + ++
Sbjct: 20 CKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQEN 79
Query: 197 VFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQE---PRARRVQCNRCN 253
+ E+ ++Y++ F V CP + C V ++Q+ + VQC C
Sbjct: 80 EIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACR 139
Query: 254 EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYIS---AHTKDCPKCNICIEKNGGC 310
FC C+ +H C +T ++ A + A K CPKC + IE++ GC
Sbjct: 140 MEFCSTCKASWHPGQGCPETMP-ITFLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGC 198
Query: 311 NHMQCSKCKHDFCWMCL 327
M C CKH FCW CL
Sbjct: 199 AQMMCKNCKHAFCWYCL 215
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 96.7 bits (239), Expect = 4e-20
Identities = 60/209 (28%), Positives = 87/209 (41%), Gaps = 7/209 (3%)
Query: 124 PNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSC 183
P P P +C Q + K L CQ FC +C +Q+ + +++G G ++C
Sbjct: 17 PTPGDLAPAPLITCKLCLCEQSLDKMTTLQ-ECQCIFCTACLKQYMQLAIREGCGSPITC 75
Query: 184 MAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQE 241
C E + L+P ++ + Y+R F V CP ADC V V
Sbjct: 76 PDMVCLNHGTLQEAEIACLVPVDQF-QLYQRLKFEREVHLDPYRTWCPVADCQTVCPVAS 134
Query: 242 PRARR---VQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCP 298
+ V+C C+ FC C+ +HA C + + + A K CP
Sbjct: 135 SDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCP 194
Query: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCL 327
C + IE+N GC M C CKH FCW CL
Sbjct: 195 VCRVYIERNEGCAQMMCKNCKHTFCWYCL 223
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 89.7 bits (221), Expect = 5e-18
Identities = 60/208 (28%), Positives = 91/208 (43%), Gaps = 30/208 (14%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
C V + R LLS C H+ CR C + + + + V +SC +C R +
Sbjct: 122 CLVRLPPERAPRLLS--CPHRSCRDCLRHYLRLEISES-RVPISC--PECSERLNPHDIR 176
Query: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNEV 255
LL + L KY ++ R Y+ S + CP DC VI ++ C R C
Sbjct: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
Query: 256 FCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT--------------KDCPKCN 301
FC+ C+Q++H C R+ ++T + HT K CP+C+
Sbjct: 237 FCYHCKQIWHPNQTCDMARQ------QRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCS 290
Query: 302 ICIEK--NGGCNHMQCSKCKHDFCWMCL 327
I K +G CNHM C+ C +FCW+C+
Sbjct: 291 AYIIKMNDGSCNHMTCAVCGCEFCWLCM 318
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 89.4 bits (220), Expect = 7e-18
Identities = 60/209 (28%), Positives = 91/209 (43%), Gaps = 31/209 (14%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
C V + R LLS C H+ CR C + + + + V +SC +C R +
Sbjct: 122 CLVRLPPERAPRLLS--CPHRSCRDCLRHYLRLEISES-RVPISC--PECSERLNPHDIR 176
Query: 199 PLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNEV 255
LL + L KY ++ R Y+ S + CP DC VI ++ C R C
Sbjct: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236
Query: 256 FCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHT---------------KDCPKC 300
FC+ C+Q++H C R+ ++T + HT K CP+C
Sbjct: 237 FCYHCKQIWHPNQTCDMARQ------QRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRC 290
Query: 301 NICIEK--NGGCNHMQCSKCKHDFCWMCL 327
+ I K +G CNHM C+ C +FCW+C+
Sbjct: 291 SAYIIKMNDGSCNHMTCAVCGCEFCWLCM 319
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 87.0 bits (214), Expect = 3e-17
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 19/205 (9%)
Query: 139 CAVCMQFVRKENLLSL-ACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C +C+ K+ + C H+ C C Q+ + + + V +SC +C R +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISC--PECTERFNPHDI 188
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNE 254
+L ++ L EKY ++ R ++ + + CP DC VI ++ C R C
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248
Query: 255 VFCFKCRQMYHAPTDCAT----------IRKWLTKCADDSETANYISAHTKDCPKCNICI 304
FC+ C+Q++H C +R + S+ + + K CP+C I
Sbjct: 249 EFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYI 308
Query: 305 EK--NGGCNHMQCSKCKHDFCWMCL 327
K +G CNHM C+ C +FCW+C+
Sbjct: 309 IKMNDGSCNHMTCAVCGCEFCWLCM 333
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 87.0 bits (214), Expect = 3e-17
Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 19/205 (9%)
Query: 139 CAVCMQFVRKENLLSL-ACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
C +C+ K+ + C H+ C C Q+ + + + V +SC +C R +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISC--PECTERFNPHDI 188
Query: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNE 254
+L ++ L EKY ++ R ++ + + CP DC VI ++ C R C
Sbjct: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248
Query: 255 VFCFKCRQMYHAPTDCAT----------IRKWLTKCADDSETANYISAHTKDCPKCNICI 304
FC+ C+Q++H C +R + S+ + + K CP+C I
Sbjct: 249 EFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYI 308
Query: 305 EK--NGGCNHMQCSKCKHDFCWMCL 327
K +G CNHM C+ C +FCW+C+
Sbjct: 309 IKMNDGSCNHMTCAVCGCEFCWLCM 333
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 77.4 bits (189), Expect = 3e-14
Identities = 53/220 (24%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDG-------VGVGVSCMAQDCPLR 191
C C + +H C C+ +C + D +G + C+A CP
Sbjct: 89 CITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVA-GCPNS 147
Query: 192 TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNR 251
++ + EE +Y++Y + V + LCP C + + EP R+V C
Sbjct: 148 LIKELHHFRILGEEQYNRYQQYGAEECVLQMGGV-LCPRPGCGAGL-LPEPDQRKVTCEG 205
Query: 252 -----CNEVFCFKCRQMYHAPTDCATI--------------RKWLTKCADDSETANYISA 292
C FC +C++ YH +C+ + + + ++ + I
Sbjct: 206 GNGLGCGFAFCRECKEAYHEG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKK 264
Query: 293 HTKDCPKCNICIEKNGGCNHMQC--SKCKHDFCWMCLGDW 330
TK CP+C++ +EKNGGC HM+C +C+ ++CW C +W
Sbjct: 265 TTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 304
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 77.4 bits (189), Expect = 3e-14
Identities = 53/220 (24%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDG-------VGVGVSCMAQDCPLR 191
C C + +H C C+ +C + D +G + C+A CP
Sbjct: 210 CITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVA-GCPNS 268
Query: 192 TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNR 251
++ + EE +Y++Y + V + LCP C + + EP R+V C
Sbjct: 269 LIKELHHFRILGEEQYNRYQQYGAEECVLQMGGV-LCPRPGCGAGL-LPEPDQRKVTCEG 326
Query: 252 -----CNEVFCFKCRQMYHAPTDCATI--------------RKWLTKCADDSETANYISA 292
C FC +C++ YH +C+ + + + ++ + I
Sbjct: 327 GNGLGCGFAFCRECKEAYHEG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKK 385
Query: 293 HTKDCPKCNICIEKNGGCNHMQC--SKCKHDFCWMCLGDW 330
TK CP+C++ +EKNGGC HM+C +C+ ++CW C +W
Sbjct: 386 TTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 425
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 77.4 bits (189), Expect = 3e-14
Identities = 53/220 (24%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDG-------VGVGVSCMAQDCPLR 191
C C + +H C C+ +C + D +G + C+A CP
Sbjct: 238 CITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVA-GCPNS 296
Query: 192 TPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNR 251
++ + EE +Y++Y + V + LCP C + + EP R+V C
Sbjct: 297 LIKELHHFRILGEEQYNRYQQYGAEECVLQMGGV-LCPRPGCGAGL-LPEPDQRKVTCEG 354
Query: 252 -----CNEVFCFKCRQMYHAPTDCATI--------------RKWLTKCADDSETANYISA 292
C FC +C++ YH +C+ + + + ++ + I
Sbjct: 355 GNGLGCGFAFCRECKEAYHEG-ECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKK 413
Query: 293 HTKDCPKCNICIEKNGGCNHMQC--SKCKHDFCWMCLGDW 330
TK CP+C++ +EKNGGC HM+C +C+ ++CW C +W
Sbjct: 414 TTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 453
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 69.3 bits (168), Expect = 7e-12
Identities = 27/81 (33%), Positives = 43/81 (53%)
Query: 246 RVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIE 305
++QC C V+CFKC +H +C +K + + + + CPKC I I+
Sbjct: 80 KIQCPTCQFVWCFKCHSPWHEGVNCKEYKKGDKLLRHWASEIEHGQRNAQKCPKCKIHIQ 139
Query: 306 KNGGCNHMQCSKCKHDFCWMC 326
+ GC+HM CS+C +FC+ C
Sbjct: 140 RTEGCDHMTCSQCNTNFCYRC 160
>gi|109150431 ring finger protein 31 [Homo sapiens]
Length = 1072
Score = 67.4 bits (163), Expect = 3e-11
Identities = 51/208 (24%), Positives = 85/208 (40%), Gaps = 25/208 (12%)
Query: 139 CAVCMQFVRKENLLSL-ACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197
CAVC + + +L +C+ C C+ QH ++ +K+ + C A P T + +
Sbjct: 699 CAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQL 758
Query: 198 FPLLP--NEELREK--------YRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRV 247
+ +LRE + + L + + C A C + E
Sbjct: 759 LSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGF-IYEREQLEA 815
Query: 248 QCNRCNEVFCFKCRQMY---HAPTDCATIRKWLTKCADDSE-----TANYISAHTKDCPK 299
C +C++ FC +C++ + H C + W K +D E A Y+ + DCPK
Sbjct: 816 TCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNW--KRMNDPEYQAQGLAMYLQENGIDCPK 873
Query: 300 CNICIE-KNGGCNHMQCSKCKHDFCWMC 326
C GGC H C++C+H FC C
Sbjct: 874 CKFSYALARGGCMHFHCTQCRHQFCSGC 901
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 9/193 (4%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
C C E L A H FC+ C ++ V + +SCM C P +
Sbjct: 515 CRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELE 574
Query: 199 PLLPNEELREKYRRYLFRDYVESHY-QLQLCPGADCPMVIRVQEPRARRVQC--NRCNEV 255
+LP L + Y R + ++ +L CP P ++ + +R C C +
Sbjct: 575 KVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALL---DSDVKRFSCPNPHCRKE 631
Query: 256 FCFKCRQMY--HAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHM 313
C KC+ ++ H C + + S +A + C KC + K+ GCN M
Sbjct: 632 TCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRM 691
Query: 314 QCSKCKHDFCWMC 326
C +C C++C
Sbjct: 692 SC-RCGAQMCYLC 703
Score = 30.8 bits (68), Expect = 2.9
Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)
Query: 275 KWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKT 332
K+ + A++ A Y + CP C+ + C C+ + C C G WK
Sbjct: 584 KYYERKAEEEVAAAYADELVR-CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKE 642
Query: 333 HGSEYYECSRYKENPDI 349
H C E DI
Sbjct: 643 HNG--LTCEELAEKDDI 657
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 9/193 (4%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
C C E L A H FC+ C ++ V + +SCM C P +
Sbjct: 572 CRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELE 631
Query: 199 PLLPNEELREKYRRYLFRDYVESHY-QLQLCPGADCPMVIRVQEPRARRVQC--NRCNEV 255
+LP L + Y R + ++ +L CP P ++ + +R C C +
Sbjct: 632 KVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALL---DSDVKRFSCPNPHCRKE 688
Query: 256 FCFKCRQMY--HAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHM 313
C KC+ ++ H C + + S +A + C KC + K+ GCN M
Sbjct: 689 TCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRM 748
Query: 314 QCSKCKHDFCWMC 326
C +C C++C
Sbjct: 749 SC-RCGAQMCYLC 760
Score = 30.8 bits (68), Expect = 2.9
Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)
Query: 275 KWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKT 332
K+ + A++ A Y + CP C+ + C C+ + C C G WK
Sbjct: 641 KYYERKAEEEVAAAYADELVR-CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKE 699
Query: 333 HGSEYYECSRYKENPDI 349
H C E DI
Sbjct: 700 HNG--LTCEELAEKDDI 714
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 27/210 (12%)
Query: 136 PHHCAVCMQFVRK-ENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQD----CPL 190
P C VC + E ++ C H FCR C + +++ VSC D C
Sbjct: 237 PAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSG 292
Query: 191 RTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQL---CPGADCPMVIRVQEPRARRV 247
+ E + LL E+ Y+R+L + + C DC ++
Sbjct: 293 KLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD-VNEF 347
Query: 248 QCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTK---------DCP 298
C C V C C+ + H +C ++ L A + A + K CP
Sbjct: 348 TCPVCFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCP 406
Query: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
+C I ++K GC+ ++C+ C + CW+ G
Sbjct: 407 QCQIVVQKKDGCDWIRCTVCHTEICWVTKG 436
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 27/210 (12%)
Query: 136 PHHCAVCMQFVRK-ENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQD----CPL 190
P C VC + E ++ C H FCR C + +++ VSC D C
Sbjct: 279 PAECPVCYSVLAPGEAVVLRECLHTFCRECLQG----TIRNSQEAEVSCPFIDNTYSCSG 334
Query: 191 RTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQL---CPGADCPMVIRVQEPRARRV 247
+ E + LL E+ Y+R+L + + C DC ++
Sbjct: 335 KLLEREIKALLTPED----YQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDD-VNEF 389
Query: 248 QCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTK---------DCP 298
C C V C C+ + H +C ++ L A + A + K CP
Sbjct: 390 TCPVCFHVNCLLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCP 448
Query: 299 KCNICIEKNGGCNHMQCSKCKHDFCWMCLG 328
+C I ++K GC+ ++C+ C + CW+ G
Sbjct: 449 QCQIVVQKKDGCDWIRCTVCHTEICWVTKG 478
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 40.0 bits (92), Expect = 0.005
Identities = 66/297 (22%), Positives = 108/297 (36%), Gaps = 55/297 (18%)
Query: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCP-LR------ 191
C C + L L CQH C C ++ L VG Q P LR
Sbjct: 33 CPACKELFTHP--LILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSM 90
Query: 192 ----------------TPEDFVFPLLPNE---ELREKYRRYLFRDY-----VESHYQLQL 227
TP VFP E +L E+ LFR++ VE + Q
Sbjct: 91 DKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAAR 150
Query: 228 CPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETA 287
A + + P+ C C+ +C +C +++H W T A
Sbjct: 151 AATAIMCDLCK-PPPQESTKSCMDCSASYCNECFKIHHP---------WGTIKAQHE--- 197
Query: 288 NYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCL--GDWKTHG----SEYYECS 341
Y+ T PK +C E +M C C+ C +C G+ H S Y+
Sbjct: 198 -YVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTL 256
Query: 342 RYKENPDI-VNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQT-YQRIHEKIQER 396
+ K + DI +++Q + + + + E + + + EA T ++++ E ++ER
Sbjct: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEER 313
>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
Length = 337
Score = 39.3 bits (90), Expect = 0.008
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 4 DMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDV-EQQGADAFDPE 57
D +S+ + EEDYD + EE++E++ + G +E+ + DV +++G + FD E
Sbjct: 239 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
Length = 376
Score = 39.3 bits (90), Expect = 0.008
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 4 DMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDV-EQQGADAFDPE 57
D +S+ + EEDYD + EE++E++ + G +E+ + DV +++G + FD E
Sbjct: 278 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 332
>gi|33636758 ring finger protein 146 [Homo sapiens]
Length = 358
Score = 38.5 bits (88), Expect = 0.014
Identities = 26/116 (22%), Positives = 49/116 (42%), Gaps = 16/116 (13%)
Query: 260 CRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCK 319
C ++ H+ T RK C++ +A + P+C IC++ C H CK
Sbjct: 4 CGEIDHSINMLPTNRKANESCSN--------TAPSLTVPECAICLQT---CVHPVSLPCK 52
Query: 320 HDFCWMCLGDWKTHGSEYYECSR-----YKENPDIVNQSQQAQAREALKKYLFYFE 370
H FC++C+ G C + + + P +++ + A +Y +Y+E
Sbjct: 53 HVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGEYAWYYE 108
Score = 33.1 bits (74), Expect = 0.59
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 20/88 (22%)
Query: 126 PSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMA 185
PS VP CA+C+Q + +SL C+H FC C VK +G C
Sbjct: 29 PSLTVP------ECAICLQTC--VHPVSLPCKHVFCYLC--------VKGASWLGKRCAL 72
Query: 186 QDCPLRTPEDFVF--PLLPNEELREKYR 211
C PEDF+ LL EEL+ R
Sbjct: 73 --CRQEIPEDFLDKPTLLSPEELKAASR 98
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 37.4 bits (85), Expect = 0.031
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 17/77 (22%)
Query: 3 VDMNSQGSDSNEEDYDPNCEEEEEEEEDD----PGDIEDYYVGVASDVEQQGADAFDPEE 58
+++NS + EE+ + EEEEEEEE+D D E+Y+ + E++ + F+ E
Sbjct: 881 ININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYF-----EEEEEEEEEFEEE- 934
Query: 59 YQFTCLTYKESEGALNE 75
++E EG L E
Sbjct: 935 -------FEEEEGELEE 944
Score = 31.6 bits (70), Expect = 1.7
Identities = 14/41 (34%), Positives = 24/41 (58%)
Query: 11 DSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGA 51
+ E + + EEE+EEEE++ ++ED G A ++GA
Sbjct: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA 976
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo
sapiens]
Length = 1692
Score = 37.0 bits (84), Expect = 0.041
Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 285 ETANYISAHTKDCPKCNICIEKN--GGCNHMQCSKCKHDFCWMCLG 328
E Y H D P C IC + GC H+ CS C+ FC C G
Sbjct: 101 EARRYQGEHKDDAPTCGICHKTKFADGCGHL-CSYCRTKFCARCGG 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,101,680
Number of Sequences: 37866
Number of extensions: 1022739
Number of successful extensions: 11091
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 131
Number of HSP's successfully gapped in prelim test: 146
Number of HSP's that attempted gapping in prelim test: 8678
Number of HSP's gapped (non-prelim): 1524
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.