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Search of human proteins with 54312078
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54312078 netrin G1 isoform 3 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 939 0.0
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 917 0.0
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 779 0.0
gi|190014607 netrin G2 [Homo sapiens] 440 e-123
gi|148613884 netrin 1 [Homo sapiens] 175 6e-44
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 152 4e-37
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 145 5e-35
gi|21264602 laminin alpha 5 [Homo sapiens] 127 3e-29
gi|5453810 netrin 3 [Homo sapiens] 124 2e-28
gi|93204871 netrin 4 [Homo sapiens] 120 2e-27
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 116 4e-26
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 116 5e-26
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 116 5e-26
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 112 7e-25
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 112 7e-25
gi|143770880 laminin, beta 4 [Homo sapiens] 103 4e-22
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 99 1e-20
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 92 7e-19
gi|219842266 usherin isoform B [Homo sapiens] 65 9e-11
gi|219842259 usherin isoform A [Homo sapiens] 65 9e-11
gi|24308065 netrin 5 [Homo sapiens] 56 7e-08
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 55 1e-07
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 55 1e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 49 7e-06
gi|55770876 notch4 preproprotein [Homo sapiens] 49 7e-06
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 49 1e-05
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 48 2e-05
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 939 bits (2427), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGS 420
IGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGS
Sbjct: 361 IGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGS 420
Query: 421 PALLLLTTLLGTASPLVF 438
PALLLLTTLLGTASPLVF
Sbjct: 421 PALLLLTTLLGTASPLVF 438
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 917 bits (2369), Expect = 0.0
Identities = 437/480 (91%), Positives = 437/480 (91%), Gaps = 42/480 (8%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IG------------------------------------------TNVCDNELLHCQNGGT 378
IG NVCDNELLHCQNGGT
Sbjct: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGT 420
Query: 379 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 438
CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 421 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 480
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 779 bits (2012), Expect = 0.0
Identities = 369/400 (92%), Positives = 371/400 (92%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 400
IG C C + + C G CE R
Sbjct: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCR 400
Score = 183 bits (465), Expect = 2e-46
Identities = 95/151 (62%), Positives = 100/151 (66%), Gaps = 22/151 (14%)
Query: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347
+ D V C CN ++ N CEC+ TTGP C +C G W G
Sbjct: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDEC---LPGNSWHYG------ 461
Query: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC 407
C P NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC
Sbjct: 462 ------CQP-------NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC 508
Query: 408 GSDSGQGAPPHGSPALLLLTTLLGTASPLVF 438
GSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 509 GSDSGQGAPPHGSPALLLLTTLLGTASPLVF 539
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 440 bits (1132), Expect = e-123
Identities = 198/351 (56%), Positives = 255/351 (72%), Gaps = 2/351 (0%)
Query: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
Query: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
Query: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
Query: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
Query: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
Query: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHC 373
GPDCGKCKKN++ R W GSYLP+P G+ N C + S G C C
Sbjct: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRC 362
Score = 85.5 bits (210), Expect = 9e-17
Identities = 56/153 (36%), Positives = 65/153 (42%), Gaps = 28/153 (18%)
Query: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347
+ D V C CN +V N CEC GP C C + W G Y
Sbjct: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY---- 452
Query: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA--- 404
NVCD++ L CQNGGTC N RC CP YTG+ CE+ RC+ A
Sbjct: 453 ---------------PNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDD 497
Query: 405 GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 436
G D GA P PA LL LLG A+ L
Sbjct: 498 GGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 175 bits (444), Expect = 6e-44
Identities = 114/367 (31%), Positives = 170/367 (46%), Gaps = 41/367 (11%)
Query: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
Query: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
Query: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHD------- 231
Query: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 232 FDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
Query: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIG 362
CV D + L C+C HNT GP+C +CK + RPW + + A C
Sbjct: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCR 351
Query: 363 TNVCDNELLHCQNGGTC----HNNVRCLCPAAYTGI------------LCEKLRCEEAGS 406
N+ +L ++GG C HN C G C+ C G+
Sbjct: 352 FNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA 411
Query: 407 CGSDSGQ 413
G Q
Sbjct: 412 AGKTCNQ 418
Score = 31.2 bits (69), Expect = 1.9
Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 294 RGRCK-CNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKG 349
R CK C+ H T C C+ TG C +C K YQ + IP
Sbjct: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
Query: 350 TANTCIPSISSIGTNVCDNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEEAG 405
T S+ CD+ +C+ + G N++ C Y + L+ ++AG
Sbjct: 458 PPTTAASSVEE--PEDCDS---YCKASKGKLKINMKKYCKKDY-AVQIHILKADKAG 508
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 152 bits (385), Expect = 4e-37
Identities = 114/346 (32%), Positives = 158/346 (45%), Gaps = 42/346 (12%)
Query: 71 TCGDPPETFC----AMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE FC A G C CDA+ P+ H + DF + ST+WQS +
Sbjct: 53 TCGSPPEDFCPHVGAAGAGAHCQR-CDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFG 111
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP VNITL K E+T + + F + RP+ + K W+PYQ+Y+ C
Sbjct: 112 VQYPT--SVNITLRLGKAYEIT-YVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQ 168
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ P+ CT E+S + + F L S
Sbjct: 169 KTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFST-----------LEGRPSA 216
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y + + L+++ T T+L I L L +IF D L Y+YA+SD V GRCKCN
Sbjct: 217 YN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNG 275
Query: 302 HATVCVYDNS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
HA+ C D + +L C C+HNTTG DC +C +Q RPW+ G+ A+ C+P S
Sbjct: 276 HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-----AEAAHECLPCNCS 330
Query: 361 IGTNVC--DNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEE 403
+ C D EL +GG CH+ C G CE RC+E
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHH-----CRDHTAGPHCE--RCQE 369
Score = 42.7 bits (99), Expect = 6e-04
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGS----YLPIPKGTAN 352
C CN H T D + C C H+T GP C +C + G P++ + P P +A
Sbjct: 707 CTCNQHGTC---DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
Query: 353 TCIPSISSIGTNVCDNELLHCQNG 376
T IP + VC HC G
Sbjct: 764 TTIPESREV---VC----THCPPG 780
Score = 34.3 bits (77), Expect = 0.23
Identities = 26/114 (22%), Positives = 39/114 (34%), Gaps = 38/114 (33%)
Query: 297 CKCNLHATVCVYDNSKLTC--------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C C+ + C +D C +T GP C +C++N+ W P
Sbjct: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY--HWDP-------- 376
Query: 349 GTANTCIPSISSIGTNVCDNELLHCQNGGT----CHNNVRCLCPAAYTGILCEK 398
C P CD CQ+ G+ C + C C TG C++
Sbjct: 377 --RMPCQP---------CD-----CQSAGSLHLQCDDTGTCACKPTVTGWKCDR 414
Score = 34.3 bits (77), Expect = 0.23
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 19/109 (17%)
Query: 317 CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNG 376
C HNTTG C C++ + G +P P K +C P S CD C
Sbjct: 834 CLHNTTGDHCEHCQEGFYGSALAP---RPADKCMPCSCHPQGSVSEQMPCDPVTGQC--- 887
Query: 377 GTCHNNVRCL-CPAAYTGIL-------CEKLRCEEAGS----CGSDSGQ 413
+C +V C Y G C +C GS C +GQ
Sbjct: 888 -SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
Score = 30.4 bits (67), Expect = 3.3
Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 11/80 (13%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI---PKGTANT 353
C C ++ + + TC C+ TG C +C + S G P P G+ +T
Sbjct: 383 CDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHS--LSEGGCRPCTCNPAGSLDT 440
Query: 354 C------IPSISSIGTNVCD 367
C P ++ N+CD
Sbjct: 441 CDPRSGRCPCKENVEGNLCD 460
Score = 30.0 bits (66), Expect = 4.3
Identities = 26/115 (22%), Positives = 38/115 (33%), Gaps = 28/115 (24%)
Query: 315 CECEHNTTGPDCGKCKKNY----QGRPWSPGSYLPI--------PKGTANTCIPSISS-- 360
C C + T DC +C + GR P+ PK TC P ++
Sbjct: 887 CSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQA 946
Query: 361 --------IGTNVCDNELLHCQNGGT----CHNNVRCLCPAAYTGILCEKLRCEE 403
G ++ C G CH N C+C + G C+ RC +
Sbjct: 947 CDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCD--RCHD 999
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 145 bits (367), Expect = 5e-35
Identities = 106/343 (30%), Positives = 153/343 (44%), Gaps = 40/343 (11%)
Query: 71 TCGDPPETFCAM----GNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE +C G C+ CDA P L H + D+ + +T+WQS T
Sbjct: 68 TCGTPPEEYCVQTGVTGVTKSCHL-CDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAG 126
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP +N+TL K ++T + + F + RP+ + K W PYQYY+ C
Sbjct: 127 VQYPS--SINLTLHLGKAFDIT-YVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCE 183
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ + + + +CT+E+S + F L S
Sbjct: 184 NTYSKANRGFIRTGGDEQ-QALCTDEFSDISPLTGGNVAFST-----------LEGRPSA 231
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y D + L+++ T TD+R+ L L E+F D L Y+YAISD V GRCKCN
Sbjct: 232 YN-FDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNG 290
Query: 302 HATVCVYDN-SKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
HA+ C+ + KL C C+HNT G DC KC + RPW + +A+ C+P +
Sbjct: 291 HASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRAT-----AESASECLPCDCN 345
Query: 361 IGTNVC--DNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLR 400
+ C D EL +GG C N C G CE+ R
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTN-----CQDNTDGAHCERCR 383
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/137 (29%), Positives = 51/137 (37%), Gaps = 32/137 (23%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY----LPIPKGTAN 352
C CN H+ C D C C NT GP C KC Y G + S P P G++
Sbjct: 724 CACNGHSETC--DPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSC 781
Query: 353 TCIPSISSIGTNVCDNELLHCQNGGTCHNNVRC-LCPAAYTG---------ILCEKLRCE 402
+P + VC N C G T RC LC Y G LC +C
Sbjct: 782 AVVPKTKEV---VCTN----CPTGTT---GKRCELCDDGYFGDPLGRNGPVRLCRLCQCS 831
Query: 403 E------AGSCGSDSGQ 413
+ G+C +G+
Sbjct: 832 DNIDPNAVGNCNRLTGE 848
Score = 39.7 bits (91), Expect = 0.005
Identities = 33/109 (30%), Positives = 38/109 (34%), Gaps = 26/109 (23%)
Query: 297 CKCNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
C CNL+ T+ + CEC + TG DCG C PG Y
Sbjct: 884 CNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGAC---------DPGFY---------- 924
Query: 354 CIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCE 402
S G CD L NG +C C TG CE RCE
Sbjct: 925 --NLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCE--RCE 969
Score = 33.5 bits (75), Expect = 0.39
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 34/124 (27%)
Query: 285 FYAISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
FY + + RC C+ L +T D CEC+ TG C +C+ N+ G
Sbjct: 923 FYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFG------ 976
Query: 344 LPIPKGTANTCIPSISSIGTNVCDNELLHCQNGGT----CHNNVRCLCPAAYTGILCEKL 399
P+G C P CD C G+ C ++ RC C + G C+
Sbjct: 977 ---PEG----CKP---------CD-----CHPEGSLSLQCKDDGRCECREGFVGNRCD-- 1013
Query: 400 RCEE 403
+CEE
Sbjct: 1014 QCEE 1017
Score = 30.0 bits (66), Expect = 4.3
Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNY-QGRPWSPG 341
C C+ ++ + CEC G C +C++NY R W PG
Sbjct: 983 CDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSW-PG 1027
Score = 28.9 bits (63), Expect = 9.6
Identities = 12/45 (26%), Positives = 20/45 (44%), Gaps = 8/45 (17%)
Query: 297 CKCNLHATVCVYD--------NSKLTCECEHNTTGPDCGKCKKNY 333
C CN + C +D + C+ NT G C +C++N+
Sbjct: 342 CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF 386
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 127 bits (318), Expect = 3e-29
Identities = 94/310 (30%), Positives = 144/310 (46%), Gaps = 43/310 (13%)
Query: 58 TKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTF 117
T+ L KL + GDP +T C+ C A+ AHP D R +
Sbjct: 77 TEDLYCKLVGGPVAGGDPNQTIRGQ----YCDI-CTAANSNKAHPASNAIDGTER----W 127
Query: 118 WQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQY 177
WQS + +VN+TL + + ++ S RPD +LE+S+D+GRT+QP+Q+
Sbjct: 128 WQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
Query: 178 YAT---DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAG 234
+A+ DCL+ F P++++ +++ ICT EY S+I+ E +
Sbjct: 188 FASSKRDCLERF--GPQTLERITRDDA--AICTTEY-------SRIVPLENGEIVVSLVN 236
Query: 235 PRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHLARYFYAI 288
R M Y L LR+F T++R+R LR +G+ D RY+Y+I
Sbjct: 237 GRPGAMNFSYSPL-----LREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSI 291
Query: 289 SDIKVRGRCKCNLHATVC----VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
DI + GRC C+ HA C D +L C C+HNT G C +C + +PW P +
Sbjct: 292 KDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPAT-- 349
Query: 345 PIPKGTANTC 354
+AN C
Sbjct: 350 ---ANSANEC 356
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 15/102 (14%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+C+ H+ C+ S + +C+HNT G C +C+ + S P +C
Sbjct: 1864 CQCHGHSDRCL-PGSGVCVDCQHNTEGAHCERCQAGFV-------SSRDDPSAPCVSCPC 1915
Query: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
+S N + +L GG +CLC Y G CE+
Sbjct: 1916 PLSVPSNNFAEGCVL---RGG----RTQCLCKPGYAGASCER 1950
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/101 (32%), Positives = 38/101 (37%), Gaps = 25/101 (24%)
Query: 317 CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNG 376
C +TTGP C C + G PG+ T C P GT CD H
Sbjct: 1994 CLRHTTGPRCEICAPGFYGNALLPGNC------TRCDCTP----CGTEACDPHSGH---- 2039
Query: 377 GTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 417
CLC A TG C+ RC+E G G D G P
Sbjct: 2040 --------CLCKAGVTGRRCD--RCQE-GHFGFDGCGGCRP 2069
Score = 37.0 bits (84), Expect = 0.035
Identities = 28/105 (26%), Positives = 39/105 (37%), Gaps = 8/105 (7%)
Query: 296 RCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
RC C T ++ C C N +G C C + + G P S P P + +T
Sbjct: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP----SCYPTPSSSNDTRE 483
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILCE 397
+ + CD Q G C + RCLC + G CE
Sbjct: 484 QVLPAGQIVNCDCSAAGTQ-GNACRKDPRVGRCLCKPNFQGTHCE 527
Score = 34.7 bits (78), Expect = 0.18
Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 36/119 (30%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C HAT C YD + +C+H+TTG +C +C + P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 340 PGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCE 397
P L P C C+++ GTC + RC C ++G C+
Sbjct: 419 P---LDSPH-VCRRC----------NCESDF----TDGTCEDLTGRCYCRPNFSGERCD 459
Score = 34.3 bits (77), Expect = 0.23
Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRP-------WSPGSYLPIPKGTANTCIPSISSIGTNVCD 367
C C T GP C +C Y G P PG G N C P +S + C
Sbjct: 2088 CHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCN-CPPGLSGERCDTCS 2146
Query: 368 NELLHCQNGGTCHNNVRC 385
+ GG +++ C
Sbjct: 2147 QQHQVPVPGGPVGHSIHC 2164
Score = 33.1 bits (74), Expect = 0.51
Identities = 31/140 (22%), Positives = 45/140 (32%), Gaps = 30/140 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN---- 352
C C+ T+ + C C+ GP C +C+ Y G P P+G +
Sbjct: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCD-PRGALDQLCG 645
Query: 353 -----TCIPSISSIGTNVCDNEL--------LHCQNGGTCH-----NNVRCLCPAAYTGI 394
C P + C HC G+ H + +C C TG+
Sbjct: 646 AGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGL 705
Query: 395 LCE-------KLRCEEAGSC 407
C+ EAGSC
Sbjct: 706 RCDTCVPGAYNFPYCEAGSC 725
Score = 30.4 bits (67), Expect = 3.3
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 15/106 (14%)
Query: 311 SKLTCECEHNTTGPDCGKCKKNYQG-RPWSP------GSYLPIPKGTANTCIPSISSIGT 363
+++ C C + GP C +CK + G P +P L G C P GT
Sbjct: 740 AQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQP-----GT 794
Query: 364 NVCDNELLHC-QNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCG 408
C + C Q +C + L A Y G C RC+ G+ G
Sbjct: 795 GQCFCKPHVCGQACASCKDGFFGLDQADYFG--CRSCRCDIGGALG 838
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 124 bits (311), Expect = 2e-28
Identities = 103/361 (28%), Positives = 146/361 (40%), Gaps = 48/361 (13%)
Query: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130
TCG P CDAS P AH P L+ G W+S + PL
Sbjct: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103
Query: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189
V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD +
Sbjct: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162
Query: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249
+ E +C S ++ F ++D + P L LD+
Sbjct: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207
Query: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309
+ L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D
Sbjct: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267
Query: 310 -NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDN 368
L C+C H T GPDCG+CK Y RPW + A +C N+
Sbjct: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELY 327
Query: 369 ELLHCQNGGTC----HNNVRCLCPAAYTGI------------LCEKLRCEEAGSCGSDSG 412
L ++GG C HN C G C C G+ G
Sbjct: 328 RLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCN 387
Query: 413 Q 413
Q
Sbjct: 388 Q 388
Score = 32.0 bits (71), Expect = 1.1
Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 12/124 (9%)
Query: 287 AISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSY 343
A+SD + C C+ + A + + C C+ TG C +C +Q P +P
Sbjct: 364 ALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVK 423
Query: 344 LPIPKGTANTCIPSISSIGTNVCDNELLHCQNG-GTCHNNVRCLCPAAYTGILCEKLRCE 402
PIP T ++ S + CD+ HC+ G+ +++ C Y + R E
Sbjct: 424 TPIPGPTEDS-----SPVQPQDCDS---HCKPARGSYRISLKKFCKKDYAVQVAVGARGE 475
Query: 403 EAGS 406
G+
Sbjct: 476 ARGA 479
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 120 bits (302), Expect = 2e-27
Identities = 87/318 (27%), Positives = 144/318 (45%), Gaps = 69/318 (21%)
Query: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
Query: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
Query: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
++S D+G+TW+PY+Y+AT+C F ++ VK ICT +YS+ + +
Sbjct: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKK-------GAICTSKYSSPFPCTGGEVI 197
Query: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAV-----GE 273
F+ +L DT + K+++ +T+LR++LL+ +
Sbjct: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
Query: 274 IFVDELHLARYFYAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHN 320
+ + H YAI D V+G C CN HA C+ + C C+HN
Sbjct: 241 LNEEPQHFTH--YAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHN 298
Query: 321 TTGPDCGKCKKNYQGRPW 338
T G C C Y RPW
Sbjct: 299 TAGSHCQHCAPLYNDRPW 316
Score = 43.9 bits (102), Expect = 3e-04
Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 41/149 (27%)
Query: 297 CKCNLHATVCVYD----------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY--L 344
CKCN HA C +D + + +C+HNT G C +CK PG Y L
Sbjct: 332 CKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCK---------PGFYRDL 382
Query: 345 PIPKGTANTCIP-SISSIGTNVCD-NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR-- 400
P + C P S +G+ V N + C +N C C G C++
Sbjct: 383 RRPFSAPDACKPCSCHPVGSAVLPANSVTFCD-----PSNGDCPCKPGVAGRRCDRCMVG 437
Query: 401 -----------CEEAGSCGSDSGQGAPPH 418
C+ AGSC +G H
Sbjct: 438 YWGFGDYGCRPCDCAGSCDPITGDCISSH 466
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 116 bits (291), Expect = 4e-26
Identities = 95/314 (30%), Positives = 142/314 (45%), Gaps = 59/314 (18%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNECDASTPELAHPPELMFDFEGRHP--------ST 116
TCG+ PE FC + G P N +C A+P E RHP +
Sbjct: 40 TCGEKGPEMFCKLVEHVPGRPVR-NPQCRICDGNSANPRE-------RHPISHAIDGTNN 91
Query: 117 FWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQ 176
+WQS + + + V ITL + ++ I+ + RP ILE+SLD G T+ P+Q
Sbjct: 92 WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQ 150
Query: 177 YYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFA 233
YYA ++CL +++ P+ + E+ICT YS IH + +
Sbjct: 151 YYAVSDSECLSRYNITPRRGPP-TYRADDEVICTSYYSRLVPLEHGEIHTSLING----- 204
Query: 234 GPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLA 282
R A D + KL +F + +R+RL +R ++ +D +
Sbjct: 205 ----RPSAD-----DLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTR 255
Query: 283 RYFYAISDIKVRGRCKCNLHATVCVYDNS--KLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
RY+Y+I DI V G C C HA+ C +D + KL C+CEHNT G C +C Y +PW P
Sbjct: 256 RYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRP 315
Query: 341 GSYLPIPKGTANTC 354
G+ + NTC
Sbjct: 316 GTV-----SSGNTC 324
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 31/144 (21%)
Query: 297 CKCNL---HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG-------RPWSPGSYLPI 346
C+C++ H+ VC + C+C+ N TG C +C Y G RP + +
Sbjct: 902 CECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSV 959
Query: 347 PKGTANT----CIPSISSIGTNVCDNELLHCQNG-----------GTCHNNV-RCLCPAA 390
G + C+P ++ + C + Q+G TC C+CP
Sbjct: 960 SDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPH 1019
Query: 391 YTGILCEKLRCEEAGSCGSDSGQG 414
G+ CE+ CE+ G G D+ G
Sbjct: 1020 TQGVKCEE--CED-GHWGYDAEVG 1040
Score = 43.1 bits (100), Expect = 5e-04
Identities = 33/108 (30%), Positives = 41/108 (37%), Gaps = 25/108 (23%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C+ HA C N C C HNTTG C +C + G P +GT C
Sbjct: 742 CECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEP---------SRGTPGDCQ 789
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNN----VRC-LCPAAYTGILCEK 398
P C + TCH N V C C Y+G CE+
Sbjct: 790 PC-------ACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER 830
Score = 35.4 bits (80), Expect = 0.10
Identities = 36/139 (25%), Positives = 47/139 (33%), Gaps = 36/139 (25%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-------PKG 349
C CN H+ C + K C NT G C C Y G+ S + P
Sbjct: 1403 CSCNNHSDTCDPNTGKCL-NCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPAS 1461
Query: 350 TANTCIPSISSIGTNVCDNELL-----HCQNGGTCHNNVRCLCPAAY------TGILCEK 398
+ TC+ + CD LL HC+ C ++Y G C+K
Sbjct: 1462 FSPTCV--LEGDHDFRCDACLLGYEGKHCER-----------CSSSYYGNPQTPGGSCQK 1508
Query: 399 LRCEEAGS----CGSDSGQ 413
C GS C SGQ
Sbjct: 1509 CDCNPHGSVHGDCDRTSGQ 1527
Score = 35.0 bits (79), Expect = 0.13
Identities = 47/179 (26%), Positives = 66/179 (36%), Gaps = 22/179 (12%)
Query: 255 DFFTV-TDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVR-GRCKCNLHATVCVYDNSK 312
DF +V +D+ L++ + G+ L +R ISDI + GR LH V +
Sbjct: 1309 DFMSVLSDIEYILIKASYGQ----GLQQSR----ISDISMEVGRKAEKLHPEEEVASLLE 1360
Query: 313 LTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLH 372
C C T G C C Y GS P+ C+P + ++ CD
Sbjct: 1361 -NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG-PRPLVAPCVPCSCNNHSDTCDPNTGK 1418
Query: 373 CQNGGTCHNNVRC-LCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLL 430
C N G C +C + Y G + SD A PH PA T +L
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYG---------KVTGSASDCALCACPHSPPASFSPTCVL 1468
Score = 34.7 bits (78), Expect = 0.18
Identities = 36/126 (28%), Positives = 47/126 (37%), Gaps = 30/126 (23%)
Query: 297 CKCNLHATVCVYDNS-----------------KLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C+ A C YD S + C NT G +C C Y RP
Sbjct: 327 CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RPHK 385
Query: 340 PGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILC 396
Y P N C P + S+ ++VC + LH HN +C C YTG C
Sbjct: 386 VSPYEDEPCRPCN-CDP-VGSL-SSVCIKDDLH----SDLHNGKQPGQCPCKEGYTGEKC 438
Query: 397 EKLRCE 402
+ RC+
Sbjct: 439 D--RCQ 442
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 17/89 (19%)
Query: 300 NLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSI 358
N T + D ++ C+ C +G C +C Y G P PG +C+P
Sbjct: 801 NFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPG----------ESCVPCD 850
Query: 359 SSIGTNVCDNELLHCQN-GGTCHNNVRCL 386
S NV +E HC + G C ++CL
Sbjct: 851 CS--GNVDPSEAGHCDSVTGEC---LKCL 874
Score = 31.6 bits (70), Expect = 1.5
Identities = 11/33 (33%), Positives = 16/33 (48%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKK 331
CNL +C C C+ N GP C +C++
Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 116 bits (290), Expect = 5e-26
Identities = 85/304 (27%), Positives = 133/304 (43%), Gaps = 52/304 (17%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGY-TTNSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFT-------FSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSY 343
P ++
Sbjct: 344 PAAW 347
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 22/103 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-I 355
C CN H+ C D S + C+HNT G C +C++ Y G G+ C
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGN---------AVHGSCRACPC 1736
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
P +S T NGG +VRC C A YTG CE+
Sbjct: 1737 PHTNSFATGC-------VVNGG----DVRCSCKAGYTGTQCER 1768
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 37/120 (30%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C+ HA+ C YD + C+HNT G +C +C K Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 340 PGSYLPIPKGTANTCIPSISSIGTNVCDNELLH-CQNGGTCHNNVRCLCPAAYTGILCEK 398
+P + CIP CD E C+ G + RC C + G CEK
Sbjct: 415 ------VPVDAPDGCIPC-------SCDPEHADGCEQG-----SGRCHCKPNFHGDNCEK 456
Score = 36.2 bits (82), Expect = 0.060
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 1734 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
Score = 33.9 bits (76), Expect = 0.30
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 297 CKCNL-HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-PKGTANTC 354
C C+ HA C + + C C+ N G +C KC Y P+ +PI P T ++
Sbjct: 426 CSCDPEHADGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFC--LRIPIFPVSTPSSE 481
Query: 355 IPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 400
P I C+ E + + C + RCLC G C+ R
Sbjct: 482 DPVAGDIKGCDCNLEGVLPE---ICDAHGRCLCRPGVEGPRCDTCR 524
Score = 33.9 bits (76), Expect = 0.30
Identities = 30/124 (24%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-----W--SPGSY-LPIPK 348
C CNL + ++ C C GP C C+ + P W + GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 349 GTAN-TCIPSISSIGTNVCDN---ELLHCQN-------GGTCHNNV-RCLCPAAYTGILC 396
T C P ++ + C + + HCQ GT ++N+ C C G C
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
Query: 397 EKLR 400
+ +
Sbjct: 611 SRCK 614
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 19/105 (18%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN-TCIPSISSIGTNVC---DNEL 370
C+C+ + GP C +CK Y W+ P G + C + + GT C D +
Sbjct: 599 CQCKLHVEGPTCSRCKLLY----WNLDK--ENPSGCSECKCHKAGTVSGTGECRQGDGD- 651
Query: 371 LHCQN--GG----TCHNNVRCLCPAAYTGILCEKLRCEEAGSCGS 409
HC++ GG TC + L + Y G C+ +C+ G+ S
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFG--CQGCQCDIGGALSS 694
Score = 30.0 bits (66), Expect = 4.3
Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 33/140 (23%)
Query: 297 CKCNLHATVCVYDNSKLTCECE-HNTTGPDCG------KCKKNYQGRPWS--PGSYLPIP 347
CK + + V Y L CEC TGP C C+ N GR + + P
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
Query: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGIL-------CEKLR 400
+ C P S G +C+ C+ VR C T CE
Sbjct: 1308 R-----CKP--CSCGRRLCEEMTGQCR---CPPRTVRPQCEVCETHSFSFHPMAGCEGCN 1357
Query: 401 CEEAGS-------CGSDSGQ 413
C G+ C DSGQ
Sbjct: 1358 CSRRGTIEAAMPECDRDSGQ 1377
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 116 bits (290), Expect = 5e-26
Identities = 85/304 (27%), Positives = 133/304 (43%), Gaps = 52/304 (17%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGY-TTNSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFT-------FSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSY 343
P ++
Sbjct: 344 PAAW 347
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 22/103 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-I 355
C CN H+ C D S + C+HNT G C +C++ Y G G+ C
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGN---------AVHGSCRACPC 1736
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
P +S T NGG +VRC C A YTG CE+
Sbjct: 1737 PHTNSFATGC-------VVNGG----DVRCSCKAGYTGTQCER 1768
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 37/120 (30%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C+ HA+ C YD + C+HNT G +C +C K Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 340 PGSYLPIPKGTANTCIPSISSIGTNVCDNELLH-CQNGGTCHNNVRCLCPAAYTGILCEK 398
+P + CIP CD E C+ G + RC C + G CEK
Sbjct: 415 ------VPVDAPDGCIPC-------SCDPEHADGCEQG-----SGRCHCKPNFHGDNCEK 456
Score = 36.2 bits (82), Expect = 0.060
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 1734 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
Score = 33.9 bits (76), Expect = 0.30
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 297 CKCNL-HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-PKGTANTC 354
C C+ HA C + + C C+ N G +C KC Y P+ +PI P T ++
Sbjct: 426 CSCDPEHADGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFC--LRIPIFPVSTPSSE 481
Query: 355 IPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 400
P I C+ E + + C + RCLC G C+ R
Sbjct: 482 DPVAGDIKGCDCNLEGVLPE---ICDAHGRCLCRPGVEGPRCDTCR 524
Score = 33.9 bits (76), Expect = 0.30
Identities = 30/124 (24%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-----W--SPGSY-LPIPK 348
C CNL + ++ C C GP C C+ + P W + GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 349 GTAN-TCIPSISSIGTNVCDN---ELLHCQN-------GGTCHNNV-RCLCPAAYTGILC 396
T C P ++ + C + + HCQ GT ++N+ C C G C
Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610
Query: 397 EKLR 400
+ +
Sbjct: 611 SRCK 614
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 19/105 (18%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN-TCIPSISSIGTNVC---DNEL 370
C+C+ + GP C +CK Y W+ P G + C + + GT C D +
Sbjct: 599 CQCKLHVEGPTCSRCKLLY----WNLDK--ENPSGCSECKCHKAGTVSGTGECRQGDGD- 651
Query: 371 LHCQN--GG----TCHNNVRCLCPAAYTGILCEKLRCEEAGSCGS 409
HC++ GG TC + L + Y G C+ +C+ G+ S
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFG--CQGCQCDIGGALSS 694
Score = 30.0 bits (66), Expect = 4.3
Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 33/140 (23%)
Query: 297 CKCNLHATVCVYDNSKLTCECE-HNTTGPDCG------KCKKNYQGRPWS--PGSYLPIP 347
CK + + V Y L CEC TGP C C+ N GR + + P
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307
Query: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGIL-------CEKLR 400
+ C P S G +C+ C+ VR C T CE
Sbjct: 1308 R-----CKP--CSCGRRLCEEMTGQCR---CPPRTVRPQCEVCETHSFSFHPMAGCEGCN 1357
Query: 401 CEEAGS-------CGSDSGQ 413
C G+ C DSGQ
Sbjct: 1358 CSRRGTIEAAMPECDRDSGQ 1377
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 112 bits (280), Expect = 7e-25
Identities = 103/361 (28%), Positives = 156/361 (43%), Gaps = 60/361 (16%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPK-------GTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 396
L + G A C + N+ N GG C N C GI C
Sbjct: 336 LTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN-----CTQNTAGINC 390
Query: 397 E 397
E
Sbjct: 391 E 391
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGTNVCDNELLHCQNGGTCHNNVRCL-CPAAYTGILCEKLRCEEAGSCGSDS 411
P ISS +N C G ++ RC CP Y G CE+ GS G+
Sbjct: 1469 CACPLISS-----SNNFSPSCVAEGL--DDYRCTACPRGYEGQYCERCAPGYTGSPGNPG 1521
Query: 412 GQ----GAPPHGS 420
G P+GS
Sbjct: 1522 GSCQECECDPYGS 1534
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/131 (32%), Positives = 53/131 (40%), Gaps = 33/131 (25%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C HA C D+ C C+ +T GP C KC + G P KGT+ C
Sbjct: 757 CQCFGHAESC--DDVTGECLNCKDHTGGPYCDKCLPGFYGEP---------TKGTSEDCQ 805
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCL------CPAAYTGILCEKLRCEEAGSCGS 409
P + N+ N TCH + R L CP YTG CE RC E
Sbjct: 806 PCACPL--NIPSNNF-----SPTCHLD-RSLGLICDGCPVGYTGPRCE--RCAE-----G 850
Query: 410 DSGQGAPPHGS 420
GQ + P GS
Sbjct: 851 YFGQPSVPGGS 861
Score = 38.9 bits (89), Expect = 0.009
Identities = 42/163 (25%), Positives = 60/163 (36%), Gaps = 45/163 (27%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSY----- 343
C C L+ + C D S L C+ C TGP C +C + Y G+P PG
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ 866
Query: 344 ------LPIP------KGTANTCIPSISSIGTNVCDN------------ELLHCQNGGT- 378
IP G+ C P + +C + + C GG+
Sbjct: 867 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF 926
Query: 379 ---CHNNV-RCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 417
CH+ +C C A G C+K + AG+ G S +G P
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDKCK---AGTFGLQSARGCVP 966
Score = 38.1 bits (87), Expect = 0.016
Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 19/99 (19%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQ 374
C+C +G C C + PG P P T TC+P + +++CD E CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP--TLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 375 N------GGTCHNNVRCLCPAAYTGIL------CEKLRC 401
N G C C Y GI+ C++ C
Sbjct: 1438 NCQHHTAGDFCER-----CALGYYGIVKGLPNDCQQCAC 1471
Score = 31.6 bits (70), Expect = 1.5
Identities = 19/87 (21%), Positives = 30/87 (34%), Gaps = 17/87 (19%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQ 374
C C +G C +C + + P N C + CD+E C
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYP------------RCNLCDCFLPGTDATTCDSETKKC- 1125
Query: 375 NGGTCHNNV-RCLCPAAYTGILCEKLR 400
+C + +C C GI C++ R
Sbjct: 1126 ---SCSDQTGQCTCKVNVEGIHCDRCR 1149
Score = 29.6 bits (65), Expect = 5.7
Identities = 24/102 (23%), Positives = 31/102 (30%), Gaps = 25/102 (24%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN + C C+ TG C +C Y +G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH----------GYFNFQEGGCTAC-- 1014
Query: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
S +G N CD + RC+CP G C K
Sbjct: 1015 ECSHLGNN-CDPK------------TGRCICPPNTIGEKCSK 1043
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 112 bits (280), Expect = 7e-25
Identities = 103/361 (28%), Positives = 156/361 (43%), Gaps = 60/361 (16%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPK-------GTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 396
L + G A C + N+ N GG C N C GI C
Sbjct: 336 LTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN-----CTQNTAGINC 390
Query: 397 E 397
E
Sbjct: 391 E 391
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGTNVCDNELLHCQNGGTCHNNVRCL-CPAAYTGILCEKLRCEEAGSCGSDS 411
P ISS +N C G ++ RC CP Y G CE+ GS G+
Sbjct: 1469 CACPLISS-----SNNFSPSCVAEGL--DDYRCTACPRGYEGQYCERCAPGYTGSPGNPG 1521
Query: 412 GQ----GAPPHGS 420
G P+GS
Sbjct: 1522 GSCQECECDPYGS 1534
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/131 (32%), Positives = 53/131 (40%), Gaps = 33/131 (25%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C HA C D+ C C+ +T GP C KC + G P KGT+ C
Sbjct: 757 CQCFGHAESC--DDVTGECLNCKDHTGGPYCDKCLPGFYGEP---------TKGTSEDCQ 805
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCL------CPAAYTGILCEKLRCEEAGSCGS 409
P + N+ N TCH + R L CP YTG CE RC E
Sbjct: 806 PCACPL--NIPSNNF-----SPTCHLD-RSLGLICDGCPVGYTGPRCE--RCAE-----G 850
Query: 410 DSGQGAPPHGS 420
GQ + P GS
Sbjct: 851 YFGQPSVPGGS 861
Score = 38.9 bits (89), Expect = 0.009
Identities = 42/163 (25%), Positives = 60/163 (36%), Gaps = 45/163 (27%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSY----- 343
C C L+ + C D S L C+ C TGP C +C + Y G+P PG
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ 866
Query: 344 ------LPIP------KGTANTCIPSISSIGTNVCDN------------ELLHCQNGGT- 378
IP G+ C P + +C + + C GG+
Sbjct: 867 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF 926
Query: 379 ---CHNNV-RCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 417
CH+ +C C A G C+K + AG+ G S +G P
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDKCK---AGTFGLQSARGCVP 966
Score = 38.1 bits (87), Expect = 0.016
Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 19/99 (19%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQ 374
C+C +G C C + PG P P T TC+P + +++CD E CQ
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP--TLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 375 N------GGTCHNNVRCLCPAAYTGIL------CEKLRC 401
N G C C Y GI+ C++ C
Sbjct: 1438 NCQHHTAGDFCER-----CALGYYGIVKGLPNDCQQCAC 1471
Score = 31.6 bits (70), Expect = 1.5
Identities = 19/87 (21%), Positives = 30/87 (34%), Gaps = 17/87 (19%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQ 374
C C +G C +C + + P N C + CD+E C
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYP------------RCNLCDCFLPGTDATTCDSETKKC- 1125
Query: 375 NGGTCHNNV-RCLCPAAYTGILCEKLR 400
+C + +C C GI C++ R
Sbjct: 1126 ---SCSDQTGQCTCKVNVEGIHCDRCR 1149
Score = 29.6 bits (65), Expect = 5.7
Identities = 24/102 (23%), Positives = 31/102 (30%), Gaps = 25/102 (24%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN + C C+ TG C +C Y +G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH----------GYFNFQEGGCTAC-- 1014
Query: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
S +G N CD + RC+CP G C K
Sbjct: 1015 ECSHLGNN-CDPK------------TGRCICPPNTIGEKCSK 1043
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 103 bits (256), Expect = 4e-22
Identities = 86/331 (25%), Positives = 150/331 (45%), Gaps = 68/331 (20%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNPYMCNNE----CDASTP------ 97
AC P + D+ +L TCG + +C + Y+ + CD+ P
Sbjct: 27 ACHPTTGDLLVGRNTQLMASS-TCGLSRAQKYCILS--YLEGEQKCFICDSRFPYDPYDQ 83
Query: 98 ELAHPPE-LMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGR 156
+H E ++ FE +WQS ++ V+I L + ++++TF++ R
Sbjct: 84 PNSHTIENVIVSFEPDREKKWWQSENGLDH-----VSIRLDLEALFRFS-HLILTFKTFR 137
Query: 157 PDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEY-----S 211
P M++E+S DYG W+ ++Y+A DC +F ++ V +I+C +Y S
Sbjct: 138 PAAMLVERSTDYGHNWKVFKYFAKDCATSF----PNITSGQAQGVGDIVCDSKYSDIEPS 193
Query: 212 TGYTTNSKII--HFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR- 268
TG K++ FEI++ ++ + ++D T+T+LRI +
Sbjct: 194 TGGEVVLKVLDPSFEIENPYSPY--------------------IQDLVTLTNLRINFTKL 233
Query: 269 PAVGEIFVDELH---LARYFYAISDIKVRGRCKCNLHATVC---------VYDNSKLT-- 314
+G+ + L +Y+YA+ ++ VRG C CN HA+ C V+ +
Sbjct: 234 HTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHG 293
Query: 315 -CECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
C C+HNT GP+C +CK +Q PW P + L
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Score = 38.1 bits (87), Expect = 0.016
Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 30/145 (20%)
Query: 297 CKCNLHATVCVYDNSKL---------TCE-CEHNTTGPDCGKCKKNYQGRPW----SPGS 342
C CN H++ C +D + CE C+HNT G C +C+ + P P +
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
Query: 343 YLPI---PKGT--ANTCI----PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTG 393
+P P GT C+ P++ S+ E + C N L +A
Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGL--SATDP 449
Query: 394 ILCEKLRCEEAGS-----CGSDSGQ 413
+ C+ C GS C D+GQ
Sbjct: 450 LGCQPCDCNPLGSLPFLTCDVDTGQ 474
Score = 35.4 bits (80), Expect = 0.10
Identities = 35/122 (28%), Positives = 42/122 (34%), Gaps = 20/122 (16%)
Query: 310 NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI----PSISSIGTNV 365
+S + C C TG CG+C + G P G+ P N I P S T
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGA--PCQPCACNNNIDVTDPESCSRVTGE 990
Query: 366 CDNELLHCQNGGTCHNNVRCLC-PAAYTGIL---CEKLRCEEAGSCGSDSGQGAPPHGSP 421
C LH G C LC P Y L C + C +G S PP G
Sbjct: 991 C-LRCLHNTQGANCQ-----LCKPGHYGSALNQTCRRCSCHASGV----SPMECPPGGGA 1040
Query: 422 AL 423
L
Sbjct: 1041 CL 1042
Score = 34.7 bits (78), Expect = 0.18
Identities = 35/125 (28%), Positives = 46/125 (36%), Gaps = 26/125 (20%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C CN A +C D +C C TTG +C +C Y G P S P C+
Sbjct: 863 CPCNRFAELC--DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRP--------CL 912
Query: 356 ----PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDS 411
PS + + C L ++V C C YTG C + G G+
Sbjct: 913 CPDDPSSNQYFAHSCYQNL--------WSSDVICNCLQGYTGTQCGEC---STGFYGNPR 961
Query: 412 GQGAP 416
GAP
Sbjct: 962 ISGAP 966
Score = 33.1 bits (74), Expect = 0.51
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 12/73 (16%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNE--LLH 372
C C+ G C +C++NY G P PG +P A T P +CD + +
Sbjct: 1099 CPCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKP--------ICDPDTGMCR 1148
Query: 373 CQNGGTCHNNVRC 385
C+ G + RC
Sbjct: 1149 CREGVSGQRCDRC 1161
Score = 32.7 bits (73), Expect = 0.67
Identities = 22/85 (25%), Positives = 32/85 (37%), Gaps = 20/85 (23%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQ 374
C C+ N G C +CK N+ G + + +G CD L
Sbjct: 423 CLCKENVEGAKCDQCKPNHYG-------------------LSATDPLGCQPCDCNPLGSL 463
Query: 375 NGGTCH-NNVRCLCPAAYTGILCEK 398
TC + +CLC + TG CE+
Sbjct: 464 PFLTCDVDTGQCLCLSYVTGAHCEE 488
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/348 (26%), Positives = 150/348 (43%), Gaps = 63/348 (18%)
Query: 25 LVWGHYDLCKTQIYTEEGKVWDYMA---CQPESTDMTKYLKVKLDPPDITCG-DPPETFC 80
L + LC+ ++ +E + A C P + D+ KL TCG PE +C
Sbjct: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTS-TCGLHKPEPYC 65
Query: 81 AMGNP------YMCNNEC---DASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQ 131
+ + ++CN++ + P+ ++ F +WQS E
Sbjct: 66 IVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVE-----N 120
Query: 132 VNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPK 191
V I L T ++++TF++ RP M++E+S D+G+TW Y+Y+A DC +F
Sbjct: 121 VTIQLDLEAEFHFT-HLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF----P 175
Query: 192 SVKDLSQHTVLEIICTEEYS-TGYTTNSKIIH------FEIKDRFAFFAGPRLRNMASLY 244
+ V +IIC YS +T ++I F+I+D ++ PR++N+
Sbjct: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYS----PRIQNL---- 227
Query: 245 GQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNL 301
+T+LRI+ ++ +G+ +D R Y+YA+ D+ VRG C C
Sbjct: 228 ------------LKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYG 275
Query: 302 HATVC---------VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
HA+ C V C C HNT G +C C Y PW P
Sbjct: 276 HASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRP 323
Score = 31.2 bits (69), Expect = 1.9
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 23/118 (19%)
Query: 315 CECEHNTTGPDCGKCKKNY----QGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNEL 370
C C+ N G C CK+ + P+ S P GT IP G N CD+E
Sbjct: 426 CRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGT----IP-----GGNPCDSET 476
Query: 371 LHCQNGGTCHNNVRCLCPAAYTGIL-----CEKLRCEEAG----SCGSDSGQ-GAPPH 418
HC C + G+ C C+ G SC ++SGQ PH
Sbjct: 477 GHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPH 534
Score = 31.2 bits (69), Expect = 1.9
Identities = 26/102 (25%), Positives = 36/102 (35%), Gaps = 13/102 (12%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+CN HA C D C C+ T G +C +C Y G P G+ + C
Sbjct: 867 CQCNGHADDC--DPVTGECLNCQDYTMGHNCERCLAGYYGDPII---------GSGDHCR 915
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCE 397
P G + C + C+C Y G C+
Sbjct: 916 PCPCPDGPDSGRQFARSCYQDPVT-LQLACVCDPGYIGSRCD 956
Score = 31.2 bits (69), Expect = 1.9
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
Query: 285 FYAISDIKVRGRCKCN---LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
F+ D++ R C C+ + C D S C C GP C KC + Y G
Sbjct: 1121 FWGDPDVECRA-CDCDPRGIETPQC--DQSTGQCVCVEGVEGPRCDKCTRGYSG 1171
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 35.0 bits (79), Expect = 0.13
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 40/147 (27%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLP 345
RC CN H+ C +D + C +T G +C +C+ +Y R PG+ +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY-FRNRRPGASI- 372
Query: 346 IPKGTANTCI----PSISSIGTNVCDNELLHCQNGGTCHNNV---RC-LCPAAYTGIL-- 395
TCI ++ CD C C +V RC LC +TG+
Sbjct: 373 -----QETCISCECDPDGAVPGAPCDPVTGQC----VCKEHVQGERCDLCKPGFTGLTYA 423
Query: 396 ----CEKLRCEEAGS-----CGSDSGQ 413
C + C GS C +SG+
Sbjct: 424 NPQGCHRCDCNILGSRRDMPCDEESGR 450
Score = 33.1 bits (74), Expect = 0.51
Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 315 CECE-HNTTGPDCGK------CKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCD 367
C C+ HN+ P C + C++ + G S + P T + G CD
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDV-----ATGCRACD 535
Query: 368 NELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
+ + G + RCLC TG C++
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQ 566
Score = 28.9 bits (63), Expect = 9.6
Identities = 14/43 (32%), Positives = 19/43 (44%), Gaps = 5/43 (11%)
Query: 297 CKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQGR 336
C C+ T C D + C C TGP C +C++ Y R
Sbjct: 534 CDCDFRGTEGPGC--DKASGRCLCRPGLTGPRCDQCQRGYCNR 574
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 35.0 bits (79), Expect = 0.13
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 40/147 (27%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLP 345
RC CN H+ C +D + C +T G +C +C+ +Y R PG+ +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY-FRNRRPGASI- 372
Query: 346 IPKGTANTCI----PSISSIGTNVCDNELLHCQNGGTCHNNV---RC-LCPAAYTGIL-- 395
TCI ++ CD C C +V RC LC +TG+
Sbjct: 373 -----QETCISCECDPDGAVPGAPCDPVTGQC----VCKEHVQGERCDLCKPGFTGLTYA 423
Query: 396 ----CEKLRCEEAGS-----CGSDSGQ 413
C + C GS C +SG+
Sbjct: 424 NPQGCHRCDCNILGSRRDMPCDEESGR 450
Score = 33.1 bits (74), Expect = 0.51
Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 315 CECE-HNTTGPDCGK------CKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCD 367
C C+ HN+ P C + C++ + G S + P T + G CD
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDV-----ATGCRACD 535
Query: 368 NELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
+ + G + RCLC TG C++
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQ 566
Score = 28.9 bits (63), Expect = 9.6
Identities = 14/43 (32%), Positives = 19/43 (44%), Gaps = 5/43 (11%)
Query: 297 CKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQGR 336
C C+ T C D + C C TGP C +C++ Y R
Sbjct: 534 CDCDFRGTEGPGC--DKASGRCLCRPGLTGPRCDQCQRGYCNR 574
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 35.0 bits (79), Expect = 0.13
Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 40/147 (27%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLP 345
RC CN H+ C +D + C +T G +C +C+ +Y R PG+ +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY-FRNRRPGASI- 372
Query: 346 IPKGTANTCI----PSISSIGTNVCDNELLHCQNGGTCHNNV---RC-LCPAAYTGIL-- 395
TCI ++ CD C C +V RC LC +TG+
Sbjct: 373 -----QETCISCECDPDGAVPGAPCDPVTGQC----VCKEHVQGERCDLCKPGFTGLTYA 423
Query: 396 ----CEKLRCEEAGS-----CGSDSGQ 413
C + C GS C +SG+
Sbjct: 424 NPQGCHRCDCNILGSRRDMPCDEESGR 450
Score = 33.1 bits (74), Expect = 0.51
Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 315 CECE-HNTTGPDCGK------CKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCD 367
C C+ HN+ P C + C++ + G S + P T + G CD
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDV-----ATGCRACD 535
Query: 368 NELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
+ + G + RCLC TG C++
Sbjct: 536 CDFRGTEGPGCDKASGRCLCRPGLTGPRCDQ 566
Score = 28.9 bits (63), Expect = 9.6
Identities = 14/43 (32%), Positives = 19/43 (44%), Gaps = 5/43 (11%)
Query: 297 CKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQGR 336
C C+ T C D + C C TGP C +C++ Y R
Sbjct: 534 CDCDFRGTEGPGC--DKASGRCLCRPGLTGPRCDQCQRGYCNR 574
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 92.4 bits (228), Expect = 7e-19
Identities = 100/427 (23%), Positives = 173/427 (40%), Gaps = 85/427 (19%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNP------YMCNNECDASTPELAH 101
+C P + D+ +L TCG + P+ +C + + ++C++ S + H
Sbjct: 46 SCYPATGDLLVGRADRLTASS-TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPH 104
Query: 102 PPEL---MFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPD 158
+ + F + + +WQS E P V I L T ++++TF++ RP
Sbjct: 105 SHRIQNVVTSFAPQRRAAWWQS----ENGIPA-VTIQLDLEAEFHFT-HLIMTFKTFRPA 158
Query: 159 QMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNS 218
M++E+S D+GRTW Y+Y++ DC F P + +H +++C YS +
Sbjct: 159 AMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAP---PRHWD-DVVCESRYSEIEPSTE 214
Query: 219 KIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVD 277
+ + + D P + ++++ +T+LR+ L R +G+ +D
Sbjct: 215 GEVIYRVLDPAIPIPDP-------------YSSRIQNLLKITNLRVNLTRLHTLGDNLLD 261
Query: 278 ELHLAR--YFYAISDIKVRGRCKCNLHATVCVYDNSKL---------TCECEHNTTGPDC 326
R Y+YA+ ++ VRG C C HA+ C C C+HNT G +C
Sbjct: 262 PRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNC 321
Query: 327 GKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNEL---LHCQN--GGTC-- 379
+C+ Y+ PW P G ++ C T+ C ++ L N GG C
Sbjct: 322 EQCQDFYRDLPWRPAE-----DGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG 376
Query: 380 --HNNVRCLC-----------------PAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGS 420
HN C PA C+ + ++ G C S H
Sbjct: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS--------HDD 428
Query: 421 PALLLLT 427
PAL L++
Sbjct: 429 PALGLVS 435
Score = 33.5 bits (75), Expect = 0.39
Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 9/47 (19%)
Query: 296 RCKCNLHAT---------VCVYDNSKLTCECEHNTTGPDCGKCKKNY 333
RC CNL T C D S C C N GP C +C N+
Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF 1083
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/139 (23%), Positives = 44/139 (31%), Gaps = 36/139 (25%)
Query: 303 ATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
AT C D + ++ C C TG C C + G P PG + + C +I
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCE-----CSGNIDP 994
Query: 361 IGTNVCD---------------NELLHCQNG-------GTCHNNVRCLCPAAYTGILCEK 398
+ + CD HC+ G +CH RC C T
Sbjct: 995 MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCH---RCTCNLLGT----NP 1047
Query: 399 LRCEEAGSCGSDSGQGAPP 417
+C C D G P
Sbjct: 1048 QQCPSPDQCHCDPSSGQCP 1066
Score = 31.2 bits (69), Expect = 1.9
Identities = 30/137 (21%), Positives = 43/137 (31%), Gaps = 36/137 (26%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW-------------------- 338
C+ H C+ C H+T GP C CK + G+
Sbjct: 1000 CDPHTGQCL--------RCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCP 1051
Query: 339 SPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLC-PAAYTGILCE 397
SP P C+P++ + C + +G C C C P+ G C
Sbjct: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQ---PCACHPSRARGPTCN 1108
Query: 398 KLRCEEAGSCGSDSGQG 414
E G C +G G
Sbjct: 1109 ----EFTGQCHCRAGFG 1121
Score = 30.4 bits (67), Expect = 3.3
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 287 AISDIKVRGRCKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
+ISD RC+CN TV D + +C C+ TG C +C + G
Sbjct: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 65.5 bits (158), Expect = 9e-11
Identities = 54/201 (26%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPG 341
T G C +C Y +P+ G
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQG 564
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 30/134 (22%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+CNLH +V + N CEC+ G C C++N+ G L + A C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDCD 798
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNV------RCLCPAAY----TGILCEKLRCEEAG 405
+ S GT VC+ + C C NV +CL Y LC C++ G
Sbjct: 799 TAGSLPGT-VCNAKTGQC----ICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853
Query: 406 S------CGSDSGQ 413
+ C +GQ
Sbjct: 854 TINGSLLCNKSTGQ 867
Score = 31.2 bits (69), Expect = 1.9
Identities = 40/179 (22%), Positives = 55/179 (30%), Gaps = 44/179 (24%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+ + P
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQPGFYISPG 943
Query: 339 SPGSYLP-----------IPKGTANTCIPSISSIGTNVCDN---------------ELLH 372
+ LP I C+ +SI CD + +
Sbjct: 944 NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCN 1003
Query: 373 CQNGG----TCH-NNVRCLCPAAYTGILCE-------KLRCEEAGSCGSDSGQGAPPHG 419
C G TCH +C C TG C+ L C Q PP G
Sbjct: 1004 CHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRG 1062
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 65.5 bits (158), Expect = 9e-11
Identities = 54/201 (26%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPG 341
T G C +C Y +P+ G
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQG 564
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 30/134 (22%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+CNLH +V + N CEC+ G C C++N+ G L + A C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDCD 798
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNV------RCLCPAAY----TGILCEKLRCEEAG 405
+ S GT VC+ + C C NV +CL Y LC C++ G
Sbjct: 799 TAGSLPGT-VCNAKTGQC----ICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTG 853
Query: 406 S------CGSDSGQ 413
+ C +GQ
Sbjct: 854 TINGSLLCNKSTGQ 867
Score = 31.2 bits (69), Expect = 1.9
Identities = 40/179 (22%), Positives = 55/179 (30%), Gaps = 44/179 (24%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+ + P
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQPGFYISPG 943
Query: 339 SPGSYLP-----------IPKGTANTCIPSISSIGTNVCDN---------------ELLH 372
+ LP I C+ +SI CD + +
Sbjct: 944 NATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCN 1003
Query: 373 CQNGG----TCH-NNVRCLCPAAYTGILCE-------KLRCEEAGSCGSDSGQGAPPHG 419
C G TCH +C C TG C+ L C Q PP G
Sbjct: 1004 CHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRG 1062
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 55.8 bits (133), Expect = 7e-08
Identities = 39/146 (26%), Positives = 59/146 (40%), Gaps = 30/146 (20%)
Query: 293 VRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352
+RGRC+C+ HA C C C H+TTGP C C+ +++ PW P + P+ +
Sbjct: 153 LRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT----PR-HPH 207
Query: 353 TCIPSISSIGTNVC--DNELLHC---QNGGTC----HNNVRCLCPAAYTGI--------- 394
C+P + C ++EL ++GG C H+ C G
Sbjct: 208 PCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIF 267
Query: 395 ---LCEKLRCE----EAGSCGSDSGQ 413
C +C G+C SGQ
Sbjct: 268 SRRACRACQCHPIGATGGTCNQTSGQ 293
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 22/103 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-I 355
C CN H+ C D S + C+HNT G C +C++ Y G G+ C
Sbjct: 78 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGN---------AVHGSCRACPC 127
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
P +S T NGG +VRC C A YTG CE+
Sbjct: 128 PHTNSFATGC-------VVNGG----DVRCSCKAGYTGTQCER 159
Score = 36.2 bits (82), Expect = 0.060
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 125 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 22/103 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-I 355
C CN H+ C D S + C+HNT G C +C++ Y G G+ C
Sbjct: 78 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGN---------AVHGSCRACPC 127
Query: 356 PSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
P +S T NGG +VRC C A YTG CE+
Sbjct: 128 PHTNSFATGC-------VVNGG----DVRCSCKAGYTGTQCER 159
Score = 36.2 bits (82), Expect = 0.060
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 125 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 49.3 bits (116), Expect = 7e-06
Identities = 42/137 (30%), Positives = 57/137 (41%), Gaps = 37/137 (27%)
Query: 297 CKCNLHATVC--VYDNSKLTCECEHNTTGPDCGKCKKNYQG----------RPWSPGSYL 344
C CN HA+ C VY + C+HNT GP C KCK + G RP P Y+
Sbjct: 764 CNCNGHASSCDPVYGHC---LNCQHNTEGPQCNKCKAGFFGDAMKATATSCRP-CPCPYI 819
Query: 345 PIPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRC-LCPAAYTG---------- 393
+ ++TC + + G CD C G + RC C Y G
Sbjct: 820 DASRRFSDTCF--LDTDGQATCD----ACAPG---YTGRRCESCAPGYEGNPIQPGGKCR 870
Query: 394 -ILCEKLRCEEAGSCGS 409
+ E +RC+E GS G+
Sbjct: 871 PVNQEIVRCDERGSMGT 887
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 14/130 (10%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+CN H+ +C + + +C+HN G C C +PG Y GT C P
Sbjct: 1563 CECNGHSDLC-HPETGACSQCQHNAAGEFCELC---------APGYYGDATAGTPEDCQP 1612
Query: 357 SISSIGTNVCDNELLHCQNGGTCHNNVRC-LCPAAYTGILCEKLRCEEAGSCGSDSGQGA 415
+ TN + C++ G RC C YTG CE+ G+ GQ
Sbjct: 1613 CACPL-TNPENMFSRTCESLGA--GGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCL 1669
Query: 416 PPHGSPALLL 425
P L++
Sbjct: 1670 PETNQAPLVV 1679
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 8/46 (17%)
Query: 373 CQNGGTCHNNVR----CLCPAAYTGILCE---KLRCEEAGSCGSDS 411
CQNGG CH++ C+CPA +TG CE L C +CG D+
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPE-ACGPDA 3897
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 22/136 (16%)
Query: 296 RCKCNLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNY-----QGRPWS----PGSYLP 345
RC C+ H+ C + C+ C+H+T GP C +C+ Y +G P P P
Sbjct: 1158 RCSCHGHSEACEPETG--ACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDP 1215
Query: 346 IPKGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRC-LCPAAYTGILCEKLRCEEA 404
A+TC + + G CD C G H+ C C Y G + C+
Sbjct: 1216 AAGQAAHTCF--LDTDGHPTCD----ACSPG---HSGRHCERCAPGYYGNPSQGQPCQRD 1266
Query: 405 GSCGSDSGQGAPPHGS 420
G P GS
Sbjct: 1267 SQVPGPIGCNCDPQGS 1282
Score = 32.3 bits (72), Expect = 0.87
Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 335 GRPWSPGSYLPIPKGTANTCIPSI-----SSIGTN--VCDNELLHCQNGGTCHNNVRCLC 387
GRP L + + I ++ +S+G + D + H + G H+ C C
Sbjct: 674 GRPVQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSVEECRC 733
Query: 388 PAAYTGILCE 397
P Y+G+ CE
Sbjct: 734 PIGYSGLSCE 743
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 49.3 bits (116), Expect = 7e-06
Identities = 43/129 (33%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDCG-KCKKNYQGRPWSPGSYLPIPKGTANTCIPSIS- 359
H C S C C TGP C + + G + GS P P G TC PS +
Sbjct: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG 761
Query: 360 ---SIGTNVCDNELLHCQNGGTCHN---NVRCLCPAAYTGILCE-KLR-------CEEAG 405
T+ C + C NGGTC N CLC + G CE KLR C
Sbjct: 762 PQCQTSTDYCVS--APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 406 SCGSDSGQG 414
+C DS QG
Sbjct: 820 TC-QDSPQG 827
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/130 (25%), Positives = 48/130 (36%), Gaps = 23/130 (17%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWS-PGSYLPIPKGTANTCIPS 357
C H C + +C C+ TGP+C P + G+ P P G TC
Sbjct: 665 CTCHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 358 ISSIGTNVCDNELLHCQ-----NGGTCH---NNVRCLCPAAYTGILCE-------KLRCE 402
+ C E+ C NGG+C+ C CP ++TG C+ C
Sbjct: 721 YTG---PTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCF 777
Query: 403 EAGSCGSDSG 412
G+C + G
Sbjct: 778 NGGTCVNRPG 787
Score = 38.9 bits (89), Expect = 0.009
Identities = 30/126 (23%), Positives = 41/126 (32%), Gaps = 17/126 (13%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP----- 356
H C+ C C TG C +P PGS T + P
Sbjct: 448 HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
Query: 357 SISSIGTNVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCEK-------LRCEEAGS 406
+ + TN C + C N CH N +C+C ++G CE+ C G
Sbjct: 508 QLCEVETNECASA--PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQ 565
Query: 407 CGSDSG 412
C G
Sbjct: 566 CQDQPG 571
Score = 38.1 bits (87), Expect = 0.016
Identities = 30/102 (29%), Positives = 36/102 (35%), Gaps = 12/102 (11%)
Query: 305 VCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY-LPIPKGTANTCIPSISSIGT 363
+CV C C G C + RP G+ + P G C P G
Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD--GQ 963
Query: 364 NVCDNELLHCQ-----NGGTCH---NNVRCLCPAAYTGILCE 397
N C EL CQ N GTC C CP + G+ CE
Sbjct: 964 N-CSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
Score = 37.4 bits (85), Expect = 0.027
Identities = 30/126 (23%), Positives = 45/126 (35%), Gaps = 15/126 (11%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-WSPGSYLPIPKGTANTCIPSISS 360
+ C+ S C+C G +C K Q +P + G+ P P G C P
Sbjct: 941 NGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVG 1000
Query: 361 I----GTNVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCE-------KLRCEEAGS 406
+ + C ++ H CH N C C +TG CE C G+
Sbjct: 1001 LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGT 1060
Query: 407 CGSDSG 412
C + +G
Sbjct: 1061 CEATAG 1066
Score = 36.2 bits (82), Expect = 0.060
Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 9/99 (9%)
Query: 309 DNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSI-----SSIGT 363
D++ C C GPDC N G T P S
Sbjct: 256 DSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV 315
Query: 364 NVCDNE-LLHCQNGGTCHNNV---RCLCPAAYTGILCEK 398
+ C+ + HC+NGGTC N+ C+C + + G CE+
Sbjct: 316 DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
Score = 35.4 bits (80), Expect = 0.10
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 15/95 (15%)
Query: 314 TCECEHNTTGPDCGK----CKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNE 369
TC C TG DC + C+ QG P + C+ +S G C+
Sbjct: 299 TCLCPETWTGWDCSEDVDECET--QGPPHCRNGGTCQNSAGSFHCV-CVSGWGGTSCEEN 355
Query: 370 L-----LHCQNGGTCHNNV---RCLCPAAYTGILC 396
L C G TC + V CLCP TG+LC
Sbjct: 356 LDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Score = 35.0 bits (79), Expect = 0.13
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 3/28 (10%)
Query: 373 CQNGGTCHN---NVRCLCPAAYTGILCE 397
C++GG+C N + CLCP YTG CE
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
Score = 32.3 bits (72), Expect = 0.87
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 12/55 (21%)
Query: 364 NVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILCEKLR--------CEEAGSC 407
N C + C G +CHN + +CLCP G CE LR C G+C
Sbjct: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCE-LRAGPCPPRGCSNGGTC 249
Score = 31.2 bits (69), Expect = 1.9
Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 7/43 (16%)
Query: 373 CQNGGTC---HNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSG 412
C NGG C + ++C CP + G CE+ + C D G
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACER----DVNECFQDPG 203
Score = 29.6 bits (65), Expect = 5.7
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 6/93 (6%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT-CIPSISSIGTNVCDNELLH- 372
C C +G C + + P + G G + C+P +E L
Sbjct: 537 CICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSD 596
Query: 373 -CQNGGTCHN---NVRCLCPAAYTGILCEKLRC 401
C G +C + CLCP+ +TG LCE C
Sbjct: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 48.5 bits (114), Expect = 1e-05
Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGT----NVCDNEL 370
CEC N TG +C K P + G + +G + C GT +V D
Sbjct: 388 CECPPNFTGSNCEKKVDRCTSNPCANGGQC-LNRGPSRMCRCRPGFTGTYCELHVSDCAR 446
Query: 371 LHCQNGGTCH---NNVRCLCPAAYTGILCE 397
C +GGTCH N + C CPA ++G CE
Sbjct: 447 NPCAHGGTCHDLENGLMCTCPAGFSGRRCE 476
Score = 38.9 bits (89), Expect = 0.009
Identities = 35/127 (27%), Positives = 41/127 (32%), Gaps = 21/127 (16%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW-SPGSYLPIPKGTANTCIPS 357
C AT TC C TG DC P + GS G C P
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPG 353
Query: 358 ISSIGTNVCDNELLHCQ-----NGGTCHN-----NVRCLCPAAYTGILCEKL-------R 400
+ C++ L C NGG+C N C CP +TG CEK
Sbjct: 354 YYGLH---CEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNP 410
Query: 401 CEEAGSC 407
C G C
Sbjct: 411 CANGGQC 417
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 17/77 (22%)
Query: 353 TCIPSISSIGTNV----CDNELLHCQNGGTC---HNNVRCLCPAAYTGILCEKLR----- 400
TC P + + + CD+ C+NGG+C + CLCP Y G+ CE
Sbjct: 311 TCRPGYTGVDCELELSECDSN--PCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCAD 368
Query: 401 --CEEAGSCGSDSGQGA 415
C GSC + QGA
Sbjct: 369 SPCFNGGSC-RERNQGA 384
Score = 34.7 bits (78), Expect = 0.18
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 17/59 (28%)
Query: 366 CDNELLH------CQNGGTCHN----NVRCLCPAAYTGILCE-------KLRCEEAGSC 407
CD +L + C+NG TC N + C C YTG+ CE C GSC
Sbjct: 281 CDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSC 339
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/112 (27%), Positives = 40/112 (35%), Gaps = 23/112 (20%)
Query: 317 CEHNTTGPDCGK-CKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELL---- 371
C N G +C + CKK R G Y+ P G + C+P + C +
Sbjct: 175 CSDNYYGDNCSRLCKK----RNDHFGHYVCQPDGNLS-CLPGWTG---EYCQQPICLSGC 226
Query: 372 HCQNGGTCHNNVRCLCPAAYTGILCEKL---------RCEEAGSCGSDSGQG 414
H QNG C CLC + G LC + C C D G G
Sbjct: 227 HEQNG-YCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWG 277
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 47.8 bits (112), Expect = 2e-05
Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 15/114 (13%)
Query: 304 TVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSI-- 361
T+C Y K + EC P+ KCK Y G P K P+I
Sbjct: 1296 TICKYPCGK-SREC----VAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLP 1350
Query: 362 --GTNVCDNELLH--CQNGGTCHNNVRCLCPAAYTGILCEKL----RCEEAGSC 407
G CD E + CQ+GGTC C CP + G CE + CE G C
Sbjct: 1351 GHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQC 1404
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/113 (29%), Positives = 42/113 (37%), Gaps = 12/113 (10%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-----PKGTANTCIPSISSIGTNVCDNE 369
CE PD +CK + G S P+ NTC+ G + C N
Sbjct: 1398 CENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEH-CQNA 1456
Query: 370 LLH--CQNGGTCHNNVRCLCPAAYTGILCEKLRCE----EAGSCGSDSGQGAP 416
H C+NGG C N C+C YTG +K C+ G C S P
Sbjct: 1457 FCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVGPSTCSCP 1509
Score = 39.7 bits (91), Expect = 0.005
Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 21/114 (18%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDCGK--CKKNYQ--GRPWSPGSYLPIPKGTANTCIPS 357
H C+ N C C + GP C C ++ + G+ +P P TC
Sbjct: 1368 HGGTCLAGN---LCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTC--- 1421
Query: 358 ISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKL----RCEEAGSC 407
T +CD C NGG+C+ CLCP + G C+ C+ G C
Sbjct: 1422 ----STALCDPV---CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHC 1468
Score = 34.7 bits (78), Expect = 0.18
Identities = 32/133 (24%), Positives = 46/133 (34%), Gaps = 28/133 (21%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGK-----------CKKNYQGRPWSPGSYLPIP 347
CN T C+ N C++ P C C++ Y GR + P
Sbjct: 1436 CNKPNT-CLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTC 1494
Query: 348 KGTANTCIPSISSI---------GTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCE- 397
PS S T +C L C+NGG C C CP+++ G+ C+
Sbjct: 1495 MNGGKCVGPSTCSCPSGWSGKRCNTPIC---LQKCKNGGECIAPSICHCPSSWEGVRCQI 1551
Query: 398 ---KLRCEEAGSC 407
+C G C
Sbjct: 1552 PICNPKCLYGGRC 1564
Score = 30.0 bits (66), Expect = 4.3
Identities = 23/94 (24%), Positives = 34/94 (36%), Gaps = 12/94 (12%)
Query: 314 TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTN--------- 364
TC GP C + G+ + L K PSI ++
Sbjct: 1493 TCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIP 1552
Query: 365 VCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 398
+C+ + L+ GG C C C Y+G+ CEK
Sbjct: 1553 ICNPKCLY---GGRCIFPNVCSCRTEYSGVKCEK 1583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,365,789
Number of Sequences: 37866
Number of extensions: 1042185
Number of successful extensions: 3300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 2243
Number of HSP's gapped (non-prelim): 819
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.