Guide to the Human Genome
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Search of human proteins with 54112401

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54112401 calmodulin-binding transcription activator 1 [Homo
sapiens]
         (1673 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54112401 calmodulin-binding transcription activator 1 [Homo s...  3367   0.0  
gi|29826341 calmodulin binding transcription activator 2 [Homo s...   443   e-124
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    62   4e-09
gi|91982772 mucin 17 [Homo sapiens]                                    55   4e-07
gi|156119615 myosin IXA [Homo sapiens]                                 53   2e-06
gi|194328685 myosin IB isoform 1 [Homo sapiens]                        50   2e-05
gi|240120050 myosin IB isoform 1 [Homo sapiens]                        50   2e-05
gi|44889481 myosin IB isoform 2 [Homo sapiens]                         50   2e-05
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        49   3e-05
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        49   3e-05
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       48   7e-05
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        48   7e-05
gi|161016767 mucin 21 [Homo sapiens]                                   48   9e-05
gi|4885503 myosin IA [Homo sapiens]                                    45   5e-04
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    44   0.001
gi|153945715 myosin VC [Homo sapiens]                                  44   0.001
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             44   0.002
gi|34304381 inversin isoform a [Homo sapiens]                          43   0.002
gi|34304379 inversin isoform b [Homo sapiens]                          43   0.002
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                      43   0.003
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                      43   0.003
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                      43   0.003
gi|118402590 myosin XV [Homo sapiens]                                  42   0.005
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            42   0.005
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            42   0.005
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        42   0.005
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            42   0.005
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            42   0.005
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    42   0.005
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            42   0.005

>gi|54112401 calmodulin-binding transcription activator 1 [Homo
            sapiens]
          Length = 1673

 Score = 3367 bits (8731), Expect = 0.0
 Identities = 1673/1673 (100%), Positives = 1673/1673 (100%)

Query: 1    MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLEC 60
            MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLEC
Sbjct: 1    MWRAEGKWLPKTSRKSVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLEC 60

Query: 61   LPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKD 120
            LPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKD
Sbjct: 61   LPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKD 120

Query: 121  GYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYL 180
            GYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYL
Sbjct: 121  GYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQNPDIVLVHYL 180

Query: 181  NVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSV 240
            NVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSV
Sbjct: 181  NVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSV 240

Query: 241  EQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSH 300
            EQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSH
Sbjct: 241  EQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSH 300

Query: 301  SEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPV 360
            SEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPV
Sbjct: 301  SEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPV 360

Query: 361  SISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNH 420
            SISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNH
Sbjct: 361  SISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNH 420

Query: 421  HLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETT 480
            HLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETT
Sbjct: 421  HLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETT 480

Query: 481  MNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFE 540
            MNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFE
Sbjct: 481  MNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFE 540

Query: 541  QQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFS 600
            QQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFS
Sbjct: 541  QQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFS 600

Query: 601  QTGHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSG 660
            QTGHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSG
Sbjct: 601  QTGHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSG 660

Query: 661  HVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQ 720
            HVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQ
Sbjct: 661  HVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQ 720

Query: 721  PETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDF 780
            PETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDF
Sbjct: 721  PETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDF 780

Query: 781  ISVEGGSSTIYGHQLVSGDSTALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGA 840
            ISVEGGSSTIYGHQLVSGDSTALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGA
Sbjct: 781  ISVEGGSSTIYGHQLVSGDSTALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGA 840

Query: 841  STMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN 900
            STMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN
Sbjct: 841  STMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASN 900

Query: 901  NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTL 960
            NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTL
Sbjct: 901  NYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTL 960

Query: 961  PSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQ 1020
            PSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQ
Sbjct: 961  PSSQHDWLSLDDNQFRMSILERLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQ 1020

Query: 1021 AQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATL 1080
            AQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATL
Sbjct: 1021 AQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATL 1080

Query: 1081 IQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIP 1140
            IQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIP
Sbjct: 1081 IQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIP 1140

Query: 1141 DSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSE 1200
            DSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSE
Sbjct: 1141 DSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSE 1200

Query: 1201 AISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQTRQEKL 1260
            AISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQTRQEKL
Sbjct: 1201 AISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQTRQEKL 1260

Query: 1261 LPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGK 1320
            LPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGK
Sbjct: 1261 LPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGK 1320

Query: 1321 WNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDS 1380
            WNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDS
Sbjct: 1321 WNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDS 1380

Query: 1381 AENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPATISSTMSWL 1440
            AENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPATISSTMSWL
Sbjct: 1381 AENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPATISSTMSWL 1440

Query: 1441 ASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLS 1500
            ASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLS
Sbjct: 1441 ASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLS 1500

Query: 1501 ASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRK 1560
            ASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRK
Sbjct: 1501 ASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRK 1560

Query: 1561 YKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTA 1620
            YKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTA
Sbjct: 1561 YKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTA 1620

Query: 1621 VIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLVDHRLYKRSERIEKGQGT 1673
            VIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLVDHRLYKRSERIEKGQGT
Sbjct: 1621 VIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLVDHRLYKRSERIEKGQGT 1673


>gi|29826341 calmodulin binding transcription activator 2 [Homo
           sapiens]
          Length = 1202

 Score =  443 bits (1140), Expect = e-124
 Identities = 201/249 (80%), Positives = 224/249 (89%), Gaps = 3/249 (1%)

Query: 45  NSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQN 104
           NS H+KIFLPKKLLECLP+C  LP ER RWNTNEEIA+YLITFEKH+EWL+ +PKTRPQN
Sbjct: 12  NSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQN 71

Query: 105 GSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRR 164
           GS+ILYNRKKVKYRKDGY WKKRKDGKTTREDHMKLKVQG+ECLYGCYVHSSI+PTFHRR
Sbjct: 72  GSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYVHSSIVPTFHRR 131

Query: 165 CYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHG 224
           CYWLLQNPDIVLVHYLNVPA+EDCGK C PI CSI++D++EW KW++EEL+GQLKPMFHG
Sbjct: 132 CYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHG 191

Query: 225 IKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHR 284
           IKW+C NG     FSVE LVQQILD+H TKP PRTH CLC+G LG+ GS+ HKC+S KHR
Sbjct: 192 IKWSCGNGTEE--FSVEHLVQQILDTHPTKPAPRTHACLCSGGLGS-GSLTHKCSSTKHR 248

Query: 285 IISPKVEPR 293
           IISPKVEPR
Sbjct: 249 IISPKVEPR 257



 Score =  388 bits (997), Expect = e-107
 Identities = 208/380 (54%), Positives = 253/380 (66%), Gaps = 26/380 (6%)

Query: 865  QQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASNNYSCLFDQISVPASLIQPGVLRCY 924
            Q S  +  +TD+SPEWSYPEGGVKVLITGPW EA+ +YSC+FD I+VPASL+QPGVLRCY
Sbjct: 527  QLSPALSTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCY 586

Query: 925  CPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILERLE 984
            CPAH+ GLV+LQVA     +S SV+FEY+AR   +LPS+Q DWLSLDDNQFRMSILERLE
Sbjct: 587  CPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLE 646

Query: 985  QMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEK 1044
            QME+RMAE+  + Q              G G G                FE+RVVV+ E 
Sbjct: 647  QMEKRMAEIAAAGQVPCQGPDAPPVQDEGQGPG----------------FEARVVVLVES 690

Query: 1045 MMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPL 1104
            M+ R+ W   + L H   FRGM+LLHLAAAQGYA LI+TL +WR+    S+DLE EVDPL
Sbjct: 691  MIPRSTWKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPL 750

Query: 1105 NVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLE 1164
            NVDHFSCTPLMWACALGHLEAAV+L++W+R+A+SIPDSLGRLPL +A SRGHV+LA CLE
Sbjct: 751  NVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLE 810

Query: 1165 HLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSP-EIPKGVTVIASTNPELRR 1223
             LQR E +   + P    P S  P T          ++SSP E+  G   + S       
Sbjct: 811  ELQRQEPSV--EPPFALSPPSSSPDT-------GLSSVSSPSELSDGTFSVTSAYSSAPD 861

Query: 1224 PRSEPSNYYSSESHKDYPAP 1243
                P+   +SE   +  AP
Sbjct: 862  GSPPPAPLPASEMTMEDMAP 881



 Score =  305 bits (780), Expect = 3e-82
 Identities = 198/415 (47%), Positives = 249/415 (60%), Gaps = 65/415 (15%)

Query: 1264 ALSLEEPNIRKQSPSSKQSV---PETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGK 1320
            A  LEE  +++Q PS +      P + SP  G+   S          +   A  S P G 
Sbjct: 806  ARCLEE--LQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGS 863

Query: 1321 WNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPREPMSVLMMANREVVNTE--LGSYR 1378
                 L            P      ++ AP Q+    P + L++ + E  N++  L S  
Sbjct: 864  PPPAPL------------PASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLP 911

Query: 1379 -------DSAENEECGQP--MDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGL---E 1426
                   D A  E+   P  +D I V+M++LA+ IIEATP+RIK+E+FV +  +G    E
Sbjct: 912  ALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGASMRE 971

Query: 1427 RTDPATISSTMSWLASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEK 1486
            RT    +S TMSWLASYL + D  PS+                       +P SE+ FE+
Sbjct: 972  RTGAVGLSETMSWLASYLENVDHFPSS-----------------------TPPSELPFER 1008

Query: 1487 PNL--PSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLR 1544
              L  PSA  W+EFLSASTS K+E++FA LTLSDHEQRELYEAAR++QTAFRKYKGR L+
Sbjct: 1009 GRLAVPSAPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLK 1068

Query: 1545 EQQEVAAAVIQRCYRKYKQ-------YALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAA 1597
            EQQEVAAAVIQRCYRKYKQ       +ALYKKMTQAAILIQSKFRSYYEQK+FQQSRRAA
Sbjct: 1069 EQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAA 1128

Query: 1598 VLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRH 1652
            VLIQ++YRSY++  +     RT+  +  + + S LTKKQDQAARKIMRFLRRCRH
Sbjct: 1129 VLIQQHYRSYRR--RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRH 1181



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 18/35 (51%), Positives = 25/35 (71%), Gaps = 1/35 (2%)

Query: 483 FDPDCFLNNPKQGQTYGGG-GLKAEMVSSNIRHSP 516
           FDPD FLN+P++GQTYGGG G+  +   +   H+P
Sbjct: 375 FDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 31/157 (19%)

Query: 1521 QRELY----EAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAIL 1576
            QRE Y     +A ++Q A++  K R L  ++  A+ VIQ  YR Y+QY  Y+K+  A  +
Sbjct: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKI 2582

Query: 1577 IQSKFRSYYE-------------------------QKKFQQSRRAAVLIQKYYRSYKKCG 1611
            IQ K+R+  +                         +K+ Q+  +AA++IQK+ +++K   
Sbjct: 2583 IQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRK 2642

Query: 1612 KRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR 1648
                 R T V +Q++ R   LT  + QA   I  + R
Sbjct: 2643 HYLHLRATVVSIQRRYRK--LTAVRTQAVICIQSYYR 2677



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLRE----QQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQ 1578
            ++Y+A  ++Q  +  YK +  +     Q + AA  +Q  YR YK   L K+ + AA+ IQ
Sbjct: 1773 KMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQ 1832

Query: 1579 SKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ---ARRTAVIVQQ------KLRS 1629
            S FR Y ++ K+Q   ++ + IQ++YR+YK     R      + AVI  Q      K+R 
Sbjct: 1833 SAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK 1892

Query: 1630 SLLTKKQDQAARKIMRFLRRCR 1651
             +  +++ QAA KI    R  +
Sbjct: 1893 QI--RREHQAALKIQSAFRMAK 1912



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 5/126 (3%)

Query: 1515 TLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYALYKKM 1570
            TL    QR+ ++ A ++Q+ +R +  +   +  + AA +IQ+ YR Y    +Q  LY K 
Sbjct: 1962 TLRRQLQRQ-HKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020

Query: 1571 TQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSS 1630
              A + +QS +R    +K+ +   +AAV IQ  YR+YK   K    R +A+I+Q+  R  
Sbjct: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGI 2080

Query: 1631 LLTKKQ 1636
             +T  Q
Sbjct: 2081 KITNHQ 2086



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 44/146 (30%), Positives = 74/146 (50%), Gaps = 13/146 (8%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYR-----KYKQYALYKKMTQAAIL 1576
            + ++ +A L+Q+ FR    R      + A   +QR YR     K+K Y  +  + +AAI 
Sbjct: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQ-FLHLRKAAIT 2463

Query: 1577 IQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQ 1636
            IQS +R    +KK Q+ +RAAVLIQ  +R Y+     +  +  ++++QQ  R+    K Q
Sbjct: 2464 IQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQ 2523

Query: 1637 DQAARKIMRFLRRCRHSPLVDHRLYK 1662
             +       ++R+  HS +V    YK
Sbjct: 2524 RE------NYIRQW-HSAVVIQAAYK 2542



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 26/137 (18%)

Query: 1518 DHEQRELYEAARLV-QTAFRKYKGRPLREQ---------------------QEVAAAVIQ 1555
            D ++ E+ +++ L+ Q+ FRK+K R ++ Q                     +E +A +IQ
Sbjct: 1413 DQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQ 1472

Query: 1556 RCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR- 1614
              YR +K+   Y  +    ++IQ +FR +  QK +++ + + + IQKYY++Y K    R 
Sbjct: 1473 SWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERT 1532

Query: 1615 ---QARRTAVIVQQKLR 1628
               Q R  A+ +Q   R
Sbjct: 1533 NYLQKRAAAIQLQAAFR 1549



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQ---------- 1572
            ++ +AA  +Q A+R YK R L +QQ +AA  IQ  +R Y +   Y+ + Q          
Sbjct: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYR 1859

Query: 1573 -----------------AAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ 1615
                             A I +QS +R +  +K+ ++  +AA+ IQ  +R  K   + R 
Sbjct: 1860 AYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRL 1919

Query: 1616 ARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLVDHRLYK 1662
             +  A+++QQ  R+    +KQ       M ++   RH+ LV   ++K
Sbjct: 1920 FKTAALVIQQNFRAWTAGRKQ------CMEYI-ELRHAVLVLQSMWK 1959



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 39/136 (28%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 1507 VENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQ---QEVAAAVIQRCYRKYKQ 1563
            ++  F   T    +  E  E    V      +KG+ LR Q   Q   A +IQ  YR + Q
Sbjct: 1927 IQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQ 1986

Query: 1564 YALYKKMTQAAILIQSKFRSY----YEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRT 1619
               +K M +AA+LIQ  +R+Y     +   + +++ A V +Q  YR  K   + +   + 
Sbjct: 1987 QKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKA 2046

Query: 1620 AVIVQQKLRSSLLTKK 1635
            AV +Q K R+    KK
Sbjct: 2047 AVTIQSKYRAYKTKKK 2062



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 8/111 (7%)

Query: 1526 EAARLVQTAFRKYK-GRP---LREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
            +AA L+Q  +R Y  GR    L  + + A   +Q  YR  K     K   +AA+ IQSK+
Sbjct: 1995 KAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKY 2054

Query: 1582 RSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ----ARRTAVIVQQKLR 1628
            R+Y  +KK+   R +A++IQ++YR  K    + +     ++TA+ +Q   R
Sbjct: 2055 RAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYR 2105



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 4/117 (3%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYK----QYALYKKMTQAAILI 1577
            R++  AA L+Q+ +R+Y+ +    + +     +Q+ Y   K    Q+  Y K+  + I I
Sbjct: 2187 RKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYI 2246

Query: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTK 1634
            Q+ FR    ++  +    AA LIQ+ +R+     +    ++TA+++Q+K R+ L TK
Sbjct: 2247 QAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK 2303



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 14/144 (9%)

Query: 1511 FAQLTLSDHEQRELYEAAR----LVQTAFRKYKGRPLREQ----QEVAAAVIQRCYRKYK 1562
            F Q T   H     Y+A +    ++Q  ++  +   L+ Q    Q  +A ++Q  +R  K
Sbjct: 2340 FIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMK 2399

Query: 1563 QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR-----QAR 1617
                 K M  +A LIQS+FRS   +++F   ++A + +Q+ YR+   C K +       R
Sbjct: 2400 TRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRA-TICAKHKLYQFLHLR 2458

Query: 1618 RTAVIVQQKLRSSLLTKKQDQAAR 1641
            + A+ +Q   R  ++ KK  +  R
Sbjct: 2459 KAAITIQSSYRRLMVKKKLQEMQR 2482



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)

Query: 1524 LYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY---KQYALYKKMTQAAILIQSK 1580
            ++ AA L+Q  FR    R      +  A +IQR YR +   K +  + ++  A I IQS 
Sbjct: 2262 MHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSS 2321

Query: 1581 FRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAA 1640
            +R +  +K+ ++  RAA  IQ  +R ++   + +  ++ +V++QQ+ +++   K Q Q  
Sbjct: 2322 YRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQ-- 2379

Query: 1641 RKIMRFLRRCRHSPLV 1656
                 +LR+ RHS ++
Sbjct: 2380 ----HYLRQ-RHSAVI 2390



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 45/175 (25%), Positives = 84/175 (48%), Gaps = 37/175 (21%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYALYKKMTQA---- 1573
            R  ++AA  +Q+AFR  K +      + AA VIQ+ +R +    KQ   Y ++  A    
Sbjct: 1895 RREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVL 1954

Query: 1574 -------------------AILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR 1614
                               AI+IQS +R + +QKK++  ++AA+LIQKYYR+Y   G+ +
Sbjct: 1955 QSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAY-SIGREQ 2013

Query: 1615 QARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLV---DHRLYKRSER 1666
                    +  K +++++T +      K+ + ++ C  + +     +R YK  ++
Sbjct: 2014 NH------LYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKK 2062



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/131 (25%), Positives = 64/131 (48%), Gaps = 4/131 (3%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYK----QYALYKKMTQAAILI 1577
            ++  +AA  +Q+ +R YK +        +A +IQR YR  K    Q+  Y  + + AI I
Sbjct: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKI 2100

Query: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQD 1637
            QS +R    ++  Q   RAA  I+  ++ ++        R+ A+++Q + R+    K Q 
Sbjct: 2101 QSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQR 2160

Query: 1638 QAARKIMRFLR 1648
            +    I++ ++
Sbjct: 2161 EKYLTILKAVK 2171



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 43/147 (29%), Positives = 65/147 (44%), Gaps = 8/147 (5%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
            +E ++AA ++Q   + +K R            IQR YRK     L    TQA I IQS +
Sbjct: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK-----LTAVRTQAVICIQSYY 2676

Query: 1582 RSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTK---KQDQ 1638
            R +  +K  Q   RAA LIQ +YR ++        +   V++Q   R  +  K   K   
Sbjct: 2677 RGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFL 2736

Query: 1639 AARKIMRFLRRCRHSPLVDHRLYKRSE 1665
            A +K +R ++       V  +L   SE
Sbjct: 2737 AVQKSVRTIQAAFRGMKVRQKLKNVSE 2763



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 35/112 (31%), Positives = 59/112 (52%), Gaps = 4/112 (3%)

Query: 1527 AARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
            AA  +Q AFR+ K   L  Q   AA VIQ  +R  +    +  + +  I  Q+  R + +
Sbjct: 1540 AAIQLQAAFRRLKAHNLCRQIR-AACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQ 1598

Query: 1587 QKKFQQSRRAAVLIQKYYRSY---KKCGKRRQARRTAVIVQQKLRSSLLTKK 1635
            ++K+++ ++AAV+IQ ++R+Y    K     Q  R+AVIV Q     +  +K
Sbjct: 1599 RQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARK 1650



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 13/153 (8%)

Query: 1489 LPSAADWSEFLSASTSEKVENEFAQLTLSDH-EQRELYEAARLVQTAFRKYKGR---PLR 1544
            +P+  + S+  +    EKV   +     +   + R+   AARL+QT +RKYK +      
Sbjct: 1230 IPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH 1289

Query: 1545 EQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKF---------QQSRR 1595
            +++E AA +IQ     +      +K   AA++IQ  +R    Q+K          +   +
Sbjct: 1290 QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNK 1349

Query: 1596 AAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLR 1628
            AA LIQ Y+R Y    +  + +  ++I+Q ++R
Sbjct: 1350 AASLIQGYWRRYSTRQRFLKLKYYSIILQSRIR 1382



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 33/109 (30%), Positives = 60/109 (55%), Gaps = 7/109 (6%)

Query: 1550 AAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKK 1609
            AA  IQ  YR+       ++M +AA+LIQ+ FR Y     FQ  + A++LIQ++YR+Y+ 
Sbjct: 2460 AAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRA 2519

Query: 1610 CGKRRQ----ARRTAVIVQ---QKLRSSLLTKKQDQAARKIMRFLRRCR 1651
               +R+       +AV++Q   + +++  L +++ +A+  I    R  R
Sbjct: 2520 AKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYR 2568



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 36/165 (21%)

Query: 1513 QLTLSDHEQRELYE----AARLVQTAFRKY--KGRPLREQQEVAAAVI--QRCYRKYKQY 1564
            Q  +  H+QR+ Y+    AA ++QT FR Y    + L   Q+  +AVI  Q  YR  +  
Sbjct: 1590 QAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQAR 1649

Query: 1565 ALYKKMTQAAILIQSKFRSYYEQKKF----------------QQSRR-------AAVLIQ 1601
             +Y  +  + I IQS +R+Y  +K+F                +Q+R+       AA+ IQ
Sbjct: 1650 KMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQ 1709

Query: 1602 KYYRSYKKCGKRR----QARRTAVIVQQKLRSSLLTKKQDQAARK 1642
            + YRS K   ++R    Q R + + +Q  +R   L +KQ +  RK
Sbjct: 1710 QCYRSKKIAAQKREEYMQMRESCIKLQAFVR-GYLVRKQMRLQRK 1753



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 31/125 (24%), Positives = 69/125 (55%), Gaps = 9/125 (7%)

Query: 1531 VQTAFRKYKGRPLREQQ----EVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
            +Q  +R Y  R   +Q+    + +  +IQ  +RK+KQ  + +   +A +++Q  FR ++ 
Sbjct: 1400 IQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKM-QSQVKATVILQRAFREWHL 1458

Query: 1587 QKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLR---SSLLTKKQDQAARKI 1643
            +K+ ++   +A++IQ +YR +K+  K    R   VI+Q++ R   +  L K++ ++   I
Sbjct: 1459 RKQAKE-ENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTI 1517

Query: 1644 MRFLR 1648
             ++ +
Sbjct: 1518 QKYYK 1522



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 14/140 (10%)

Query: 1520 EQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY------KQYALYKKMTQA 1573
            E   + +A +++Q  F     R        +A +IQR +R         ++ L  K  +A
Sbjct: 2973 EYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRA 3032

Query: 1574 AILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR-----QARRTAVIVQQKLR 1628
            A LIQ+ +R Y  ++ F + + AA++IQKY R+ ++ GK       + +++ VI+Q  +R
Sbjct: 3033 ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRA-REAGKHERIKYIEFKKSTVILQALVR 3091

Query: 1629 SSLLTKK--QDQAARKIMRF 1646
              L+ K+  + +A  +++ F
Sbjct: 3092 GWLVRKRFLEQRAKIRLLHF 3111



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 5/128 (3%)

Query: 1503 TSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQ-RCYRKY 1561
            T+ K+++ +  + +  H Q  ++ AA  ++  F+ ++ R        AA VIQ RC   Y
Sbjct: 2096 TAIKIQSVYRGIRVRRHIQH-MHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYY 2154

Query: 1562 K---QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARR 1618
            +   Q   Y  + +A  ++Q+ FR    ++  ++ + AA LIQ  YR Y++     + ++
Sbjct: 2155 QGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKK 2214

Query: 1619 TAVIVQQK 1626
                VQQ+
Sbjct: 2215 ITKTVQQR 2222



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 29/129 (22%), Positives = 64/129 (49%), Gaps = 7/129 (5%)

Query: 1507 VENEFAQLTLSDHEQRE---LYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQ 1563
            ++  +  + +++H+ +E   L + A  +Q+ +R  + R   +    AA  I+  ++ ++ 
Sbjct: 2073 IQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQS 2132

Query: 1564 YALYKKMTQAAILIQSKFRSYYEQK----KFQQSRRAAVLIQKYYRSYKKCGKRRQARRT 1619
               Y  M +AAI+IQ + R+YY+ K    K+    +A  ++Q  +R  +     R+ +  
Sbjct: 2133 RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192

Query: 1620 AVIVQQKLR 1628
            A ++Q   R
Sbjct: 2193 ATLIQSNYR 2201



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 13/142 (9%)

Query: 1516 LSDHEQRELYEAARLVQTAFRKY---------KGRPLREQQEVAAAVIQRCYRKYKQYAL 1566
            L+    R+   AA ++Q  +R+          K   L + Q  AA++IQ  +R+Y     
Sbjct: 1307 LAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQR 1366

Query: 1567 YKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ----ARRTAVI 1622
            + K+   +I++QS+ R       +++   A V IQ+++R+Y +  + +Q     + + +I
Sbjct: 1367 FLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLI 1426

Query: 1623 VQQKLRSSLLTKKQDQAARKIM 1644
            +Q   R     K Q Q    ++
Sbjct: 1427 IQSMFRKWKQRKMQSQVKATVI 1448



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 6/149 (4%)

Query: 1511 FAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYAL 1566
            F Q+ +      +   AA  +Q  FR ++ R        AA V+Q  YR +     Q  +
Sbjct: 2846 FLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQV 2905

Query: 1567 YKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQK 1626
            Y ++  + I+IQ++ + + +++KFQ+ + + + IQ  +R Y+   K+   +  A    Q 
Sbjct: 2906 YLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYR--AKKYLCKVKAACKIQA 2963

Query: 1627 LRSSLLTKKQDQAARKIMRFLRRCRHSPL 1655
                    K+  A  K ++ ++ C ++ L
Sbjct: 2964 WYRCWRAHKEYLAILKAVKIIQGCFYTKL 2992



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 9/149 (6%)

Query: 1503 TSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRK-YKGRPLREQQEV-------AAAVI 1554
            + EK+     Q  L  +  +  YEA +      ++ YK   L   QE        AA  I
Sbjct: 2762 SEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTI 2821

Query: 1555 QRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR 1614
            Q+ + +     L  +   AA+ IQ   +    +++F Q +RAA+ +Q Y+R+++   +  
Sbjct: 2822 QKAFCRMVTRKLETQKC-AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880

Query: 1615 QARRTAVIVQQKLRSSLLTKKQDQAARKI 1643
              R+ AV++Q   R+ L  K Q Q   +I
Sbjct: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQI 2909



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 5/95 (5%)

Query: 1551 AAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKC 1610
            A  IQR Y+ Y       K   + I IQ  FR+  ++K+F Q   +   I+K     ++C
Sbjct: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHS---IKKIEHEGQEC 3177

Query: 1611 GKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMR 1645
              +R   R A ++Q+ +R  LL KKQ++    I++
Sbjct: 3178 LSQR--NRAASVIQKAVRHFLLRKKQEKFTSGIIK 3210



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 4/113 (3%)

Query: 1516 LSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYAL----YKKMT 1571
            +S  E   L  A   +Q+  +  + R        AA  IQ+CYR  K  A     Y +M 
Sbjct: 1670 VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR 1729

Query: 1572 QAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQ 1624
            ++ I +Q+  R Y  +K+ +  R+A + +Q Y+R  K      +  +  +++Q
Sbjct: 1730 ESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQ 1782



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 44/166 (26%), Positives = 71/166 (42%), Gaps = 17/166 (10%)

Query: 1497 EFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYK--GRPLREQQEVAAAVI 1554
            EFLS   +        ++  +  +   L  AA  +Q  +R  K   +   E  ++  + I
Sbjct: 1674 EFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCI 1733

Query: 1555 Q-----RCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKK 1609
            +     R Y   KQ  L +K   A I +QS FR    ++ + +  +A ++IQ YY +YK 
Sbjct: 1734 KLQAFVRGYLVRKQMRLQRK---AVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKA 1790

Query: 1610 CGKRR----QARRTAVIVQQKLRS---SLLTKKQDQAARKIMRFLR 1648
               +R    Q ++ A  +Q   R      L K+Q  AA KI    R
Sbjct: 1791 QVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFR 1836



 Score = 39.3 bits (90), Expect = 0.032
 Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 6/83 (7%)

Query: 1550 AAAVIQRCYRKY----KQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYR 1605
            A   IQR +R Y    +    Y+ +  + ++IQS FR + +Q+K Q   +A V++Q+ +R
Sbjct: 1396 ATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKW-KQRKMQSQVKATVILQRAFR 1454

Query: 1606 SYKKCGKRRQARRTAVIVQQKLR 1628
             +    K+ +   +A+I+Q   R
Sbjct: 1455 EW-HLRKQAKEENSAIIIQSWYR 1476



 Score = 38.1 bits (87), Expect = 0.072
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 14/103 (13%)

Query: 1550 AAAVIQRCYRKYK---QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRS 1606
            AA +IQ  +RKYK       +++  +AA +IQ    ++  +++ ++   AA++IQKY+R 
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWR- 1327

Query: 1607 YKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRR 1649
                  R  A+R  ++    L+   L K Q++AA  I  + RR
Sbjct: 1328 ------RVLAQRKLLM----LKKEKLEKVQNKAASLIQGYWRR 1360



 Score = 37.7 bits (86), Expect = 0.094
 Identities = 22/85 (25%), Positives = 47/85 (55%), Gaps = 1/85 (1%)

Query: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
            +E+  +   +Q  +R+Y+ +    + + AA  IQ  YR ++ +  Y  + +A  +IQ  F
Sbjct: 2930 QEIKNSTIKIQAMWRRYRAKKYLCKVK-AACKIQAWYRCWRAHKEYLAILKAVKIIQGCF 2988

Query: 1582 RSYYEQKKFQQSRRAAVLIQKYYRS 1606
             +  E+ +F   R +A++IQ+ +R+
Sbjct: 2989 YTKLERTRFLNVRASAIIIQRKWRA 3013



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 1537 KYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRA 1596
            +++G+    Q+  AA+VIQ+  R +      +K T   I IQ+ +R Y  +KK   ++  
Sbjct: 3171 EHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIK 3230

Query: 1597 AVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR-RCRHSPL 1655
            A+ +     + +   + +  +RTA+ +       LLT K   A  + ++ L    R SPL
Sbjct: 3231 AIRLSLQVVNREIREENKLYKRTALALHY-----LLTYKHLSAILEALKHLEVVTRLSPL 3285


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 115/500 (23%), Positives = 184/500 (36%), Gaps = 55/500 (11%)

Query: 357  SSPVSISSGLNSDPDMVDS---PVVTGVSGMAV-ASVMGSLSQSATVFMSEVTNEAVYTM 412
            S+PV+ S+  +S P   +    P+ T   G  +  S+  S +  A+   S ++   V T 
Sbjct: 2838 STPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTS 2897

Query: 413  SPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDG 472
             P         SP  ++G  + +S+        T  +S  +S +P   SE   LSTT   
Sbjct: 2898 IPVTTSTEGSSSPTTAEGTSMPISTPSE---VSTPLTSILVSTVPVAGSEASTLSTTPVD 2954

Query: 473  GRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTT--VLTK 530
             R  P TT                        AE  S  I  S PGER    T+  V T 
Sbjct: 2955 TRT-PVTT--------------SAEASSSPTTAEGTSMPI--STPGERRTPLTSMSVSTM 2997

Query: 531  EIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAID 590
             + + + S   +   +  +    +  ASS   TA  + +P       ST L  +  S   
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTP 3057

Query: 591  SNKDYTSSFSQT---GHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTV 647
                  S+ S T    +SP +  T       + +S P P E  +    + S G+  +  V
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTST-------EVSSSPTPAEGTSMPISTYSEGSTPLTGV 3110

Query: 648  KTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKS 707
                +  TSS    + T    TS+      +A+    T+EG  +M TS  +EGS  L   
Sbjct: 3111 PVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEG-TSMPTSTPSEGSTPLT-- 3167

Query: 708  GELQACSSEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDI 767
                      Y+   T  V+ S      L    V    PV   +   +S           
Sbjct: 3168 ----------YMPVSTMLVVSSEDST--LSATPVDTSTPVTTSTEATSSTTAEGTSIPTS 3215

Query: 768  SFSNQFSDLINDFIS---VEGGSSTIYGHQLVSGDSTALSQSEDGARAPFTQAEMCLPCC 824
            + S   + L +  +S   V    ++I     V   +T L+ S + + +P T     +P  
Sbjct: 3216 TPSEGMTPLTSVPVSNTPVASSEASILSTTPVD-SNTPLTTSTEASSSPPTAEGTSMPTS 3274

Query: 825  SPQQGSLQLSSSEGGASTMA 844
            +P +GS  L+S     +T+A
Sbjct: 3275 TPSEGSTPLTSMPVSTTTVA 3294



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 90/395 (22%), Positives = 153/395 (38%), Gaps = 24/395 (6%)

Query: 321  SSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTG 380
            S+    +   A+ +++  S+    ST    +P +T       +S L++ P   +SPVVT 
Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTS 2549

Query: 381  --VSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSD 438
              +S  A ++   S+  S     S        +  P A      LS        + V++ 
Sbjct: 2550 TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLS-TTPVDTSIPVTTS 2608

Query: 439  GHKFAFPTTGSSESLSM-LPTNVSEEL--VLSTTLDGGRKIPETTMNFDPDCFLNNPKQG 495
                + PTT    S+ +  P+ VS  L  +L +T+        T      D         
Sbjct: 2609 TETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVD---TRTLVT 2665

Query: 496  QTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVL---TKEIKTEDTSFEQQMAKEAYSSSA 552
             + G          S++  S PGERS   T +L   T    +E ++        +   + 
Sbjct: 2666 TSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTT 2725

Query: 553  AAVAASSLTLTAGSSL---LPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
            +A A+SS T   G+S+    PS G    ST L  +  S +       S+ S T     I 
Sbjct: 2726 SAEASSSPTTAEGTSMRISTPSDG----STPLTSILVSTLPVASSEASTVSTTAVDTSIP 2781

Query: 610  QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
             T S     + +S P   E  +  + + S  +  + ++    +   SS +G + T    T
Sbjct: 2782 VTTS----TEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDT 2837

Query: 670  SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVL 704
            S+      +A+    TAEG + +  S A+EGS +L
Sbjct: 2838 STPVTTSTKASSSPTTAEG-IVVPISTASEGSTLL 2871



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 92/396 (23%), Positives = 156/396 (39%), Gaps = 63/396 (15%)

Query: 339  SSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVS-------GMAVASVMG 391
            S+    ST    +P +T    +  +S L++ P   +SPVVT              +  + 
Sbjct: 3039 STPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS 3098

Query: 392  SLSQSAT------VFMSEVTNEAVYTMS--------PTAGPNHHLLSPDASQGLVLAVSS 437
            + S+ +T      V  + VT+ A+ T+S        P         SP  S+G  +  S+
Sbjct: 3099 TYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTST 3158

Query: 438  DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
                   P+ GS+  L+ +P  VS  LV+S+         ++T++  P    + P    T
Sbjct: 3159 -------PSEGST-PLTYMP--VSTMLVVSS--------EDSTLSATP-VDTSTPVTTST 3199

Query: 498  YGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE--IKTEDTSFEQQMAKEAYSSSAAAV 555
                   AE   ++I  S P E     T+V      + + + S       ++ +    + 
Sbjct: 3200 EATSSTTAE--GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST 3257

Query: 556  AASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPS 615
             ASS   TA  + +P+      ST L  M  S        TS+ S T   P    TP  +
Sbjct: 3258 EASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTT---PADTSTPVTT 3314

Query: 616  FFLQDASKPLPVEQNTHSSLSDSGGT-------FVMPTVKTEASSQTSSCSGHVETRIES 668
            +    +S P+    +  +S    G T          P V +EAS+ +++    V+T    
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT---PVDTSTPV 3371

Query: 669  TSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVL 704
            T+S      +A+    TAEG  ++ TS  +EG+  L
Sbjct: 3372 TTST-----EASLSPTTAEG-TSIPTSSPSEGTTPL 3401



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 98/402 (24%), Positives = 153/402 (38%), Gaps = 52/402 (12%)

Query: 316  SHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDS 375
            ++S+GS+          PV+  ++ST   ST  V+      S+PV+ S+  +  P   + 
Sbjct: 3334 TYSEGSTPLTNMSFSTTPVVSSEAST--LSTTPVDT-----STPVTTSTEASLSPTTAEG 3386

Query: 376  PVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLL--SPDASQGLVL 433
              +   S     + + S+  S T  +S   N    T+S T   ++ L+  S +AS    +
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVN----TLSTTPVDSNTLVTTSTEASSSPTI 3442

Query: 434  AVSSDGHKFAFPTTGSSES--------LSMLPTNVSEELVLSTTLDGGRKIPETTM---N 482
            A  +     + PT+ +SE         LS  P   SE   LSTT       P TT    N
Sbjct: 3443 AEGT-----SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTT-PVDTSTPVTTSSPTN 3496

Query: 483  FDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFEQQ 542
              P           T G G             +P      S T V + E  T  T+    
Sbjct: 3497 SSPTTAEVTSMPTSTAGEGS------------TPLTNMPVSTTPVASSEASTLSTT-PVD 3543

Query: 543  MAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQT 602
                  SSS A+ + ++L +T      PS G  S +T L    +         TSS + T
Sbjct: 3544 SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTY--------VTSSEAST 3595

Query: 603  GHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHV 662
              +P + ++   +   Q  S P P E  T    + S  +  +  +    +S T S +G  
Sbjct: 3596 PSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA 3655

Query: 663  ETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVL 704
             T    TS+  +   Q +   +T EG  TM     +EGS  L
Sbjct: 3656 STLPVDTSTPVITSTQVSSSPVTPEG-TTMPIWTPSEGSTPL 3696



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 91/406 (22%), Positives = 151/406 (37%), Gaps = 71/406 (17%)

Query: 324  EKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSG 383
            E+     + PV     ++  +ST      DT  S+PV+ S+  +S P   +   +   + 
Sbjct: 1216 ERSTPLTSMPVRHTPVASSEASTLSTSPVDT--STPVTTSAETSSSPTTAEGTSLPTSTT 1273

Query: 384  MAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGP----NHHLLSPDASQGLVLAVS--S 437
               ++++ S+  S T+  S   +  + T   T GP    N    SP  ++G  +  S  S
Sbjct: 1274 SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYS 1333

Query: 438  DGHK--FAFP---TTGSSESLSML---------PTNVSEELVLSTTLDGGRKIPETTMNF 483
            +G     + P   T  +S ++S+L         P   S E   S T   G  +P +    
Sbjct: 1334 EGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS---- 1389

Query: 484  DPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKT-----EDTS 538
                   NP +G T                  P      S T V++ E  T      DTS
Sbjct: 1390 -------NPSEGTT------------------PLTSIPVSTTPVVSSEASTLSATPVDTS 1424

Query: 539  FEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSS 598
                 + EA SS   A   S  T T          G +P  ++   +    +S     S+
Sbjct: 1425 TPGTTSAEATSSPTTAEGISIPTSTPSE-------GKTPLKSIPVSNTPVANSEASTLST 1477

Query: 599  FSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSC 658
                 +SP +  T         +S P P E  + +  + S G+  + ++    ++  SS 
Sbjct: 1478 TPVDSNSPVVTSTAV-------SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE 1530

Query: 659  SGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVL 704
               + T    TS+      QA+    TA+G  +M+TS  +EGS  L
Sbjct: 1531 INSLSTTPAVTSTPVTTYSQASSSPTTADG-TSMQTSTYSEGSTPL 1575



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 82/372 (22%), Positives = 131/372 (35%), Gaps = 63/372 (16%)

Query: 339  SSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSAT 398
            +STE SS+       T + S ++IS+     P +   PV T       AS   +LS +  
Sbjct: 1606 ASTEASSST------TAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAS---TLSTTPV 1656

Query: 399  VFMSEVTNEAVYTMSPTAGPNHHLLSPDASQG-----LVLAVSSDGHKFAFPTTGSSESL 453
               S V      + SPT      + +   ++G      +   ++     A  T  ++   
Sbjct: 1657 DSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVD 1716

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            +  P   S E   S T   G  +P +T           P +G T                
Sbjct: 1717 NSTPVTTSTEARSSPTTSEGTSMPNST-----------PSEGTT---------------- 1749

Query: 514  HSPPGERSFSFTTVLTKEIKT-----EDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSL 568
              P      S T VL+ E  T      DTS     + EA SS   A   S  T T     
Sbjct: 1750 --PLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE-- 1805

Query: 569  LPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVE 628
                 G++P T+         +S     S+     +SP +  T         +S P P E
Sbjct: 1806 -----GMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV-------SSSPTPAE 1853

Query: 629  QNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEG 688
              + ++ + S G+  + ++    ++  SS +  + T    TS+      Q +    TA+G
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913

Query: 689  EVTMETSQAAEG 700
              +M TS   EG
Sbjct: 1914 S-SMPTSTPREG 1924



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 122/521 (23%), Positives = 186/521 (35%), Gaps = 89/521 (17%)

Query: 339  SSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSAT 398
            S+T V S   +       SSP +      S P    S   T ++ M V++   + S+++T
Sbjct: 3243 STTPVDSNTPLTTSTEASSSPPTAEG--TSMPTSTPSEGSTPLTSMPVSTTTVASSETST 3300

Query: 399  VFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVS--SDGH----KFAFPTTG--SS 450
            +  +        T +P    +    SP  + G  +  S  S+G       +F TT   SS
Sbjct: 3301 LSTTPAD-----TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS 3355

Query: 451  ESLSM--------LPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGG 502
            E+ ++         P   S E  LS T   G  IP ++           P +G T     
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSS-----------PSEGTT----- 3399

Query: 503  LKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTL 562
                         P      S T V++ E+ T  T+          S+ A+    SS T+
Sbjct: 3400 -------------PLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEAS----SSPTI 3442

Query: 563  TAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDAS 622
              G+SL P+      ST L  M  S         S+ S T   P    TP  +    ++S
Sbjct: 3443 AEGTSL-PTSTTSEGSTPLSIMPLSTTPVASSEASTLSTT---PVDTSTPVTTSSPTNSS 3498

Query: 623  KPLPVEQNTHSSLSDSGGTFV--MPTVKTE-ASSQTSSCSGH-VETRIESTSSLHLMQFQ 678
                   +  +S +  G T +  MP   T  ASS+ S+ S   V++    TSS       
Sbjct: 3499 PTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSP 3558

Query: 679  ANFQAMTAEGEVTMETSQAAEGSE----VLLKSGELQACSSEHYLQPETNGVIRSAGGVP 734
            A  Q        TM  S  +EGS     +LL S  +   +S     P T  V RS     
Sbjct: 3559 ATLQV------TTMRMSTPSEGSSSLTTMLLSSTYV---TSSEASTPSTPSVDRSTPVTT 3609

Query: 735  ILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQ 794
                N       V    +   S +   L    +S ++         IS  G +ST     
Sbjct: 3610 STQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVT-------ISEAGTAST----- 3657

Query: 795  LVSGDSTALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSS 835
            L    ST +  S   + +P T     +P  +P +GS  L++
Sbjct: 3658 LPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTT 3698



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 78/377 (20%), Positives = 143/377 (37%), Gaps = 39/377 (10%)

Query: 339 SSTEVSSTNQVEVPDTTQ--SSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQS 396
           S+ +V+S+  + +  T    S+PV+IS+  +S P   + P    +S  A +     L++ 
Sbjct: 224 STMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGP---SLSNSAPSGGSTPLTRM 280

Query: 397 ATVFMSEVTNEAVYTMSPTAGPNHHLL-------SPDASQGLVLAVS--SDGHKFAFPTT 447
               M  V++EA    +  A  N  ++       SP  ++G  +  S  ++G      T 
Sbjct: 281 PLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEG-----STP 335

Query: 448 GSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEM 507
            +S   S +P   SE   LS T              D    +    +  +         M
Sbjct: 336 LTSTPASTMPVATSEMSTLSIT------------PVDTSTLVTTSTEPSSLPTTAEATSM 383

Query: 508 VSSNIRHSPPGERSFSFTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSS 567
           ++S +        +   +T+L   + + + S    +  ++ +    A  ASS   TA  +
Sbjct: 384 LTSTLSEGSTPLTNMPVSTIL---VASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDT 440

Query: 568 LLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPV 627
            + +      ST L  M  S         S+ S T        T S     + +S P   
Sbjct: 441 SIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS----TEASSSPPTA 496

Query: 628 EQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAE 687
           E N+  + + S G+  + ++        SS +  + T    TS+      +A+  + T E
Sbjct: 497 EVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPE 556

Query: 688 GEVTMETSQAAEGSEVL 704
           G  ++ TS  +EGS  L
Sbjct: 557 G-TSIPTSTPSEGSTPL 572



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 140/689 (20%), Positives = 240/689 (34%), Gaps = 113/689 (16%)

Query: 335  LLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLS 394
            L+  S     ST  V+      +SPV  S+ ++S P   +   +   +    ++ + S+ 
Sbjct: 1819 LVANSEASTLSTTPVD-----SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIP 1873

Query: 395  QSATVFMSEVTNEAVYTMSPTAGP----NHHLLSPDASQGLVLAVSS--DGHK--FAFP- 445
             S T   S  TN    T + T+ P         SP  + G  +  S+  +G     + P 
Sbjct: 1874 VSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPV 1933

Query: 446  --TTGSSESLSMLPTNVSEELVLSTTLDGGRKIPET------------------------ 479
              TT +S  ++ L T +++     TT       P T                        
Sbjct: 1934 STTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLS 1993

Query: 480  ----------TMNFDPDCFLNNPKQGQTYG------GGGLKAEMVSSNIRHSPPGERSFS 523
                      T++  P    + P    T G       GG   +  + + R +P      S
Sbjct: 1994 TTLVVSSEASTLSTTP-VDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVS 2052

Query: 524  FTTVLTKE---IKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTT 580
             T V++ E   + T     + Q+     +SS+A    SS+T++A     PS G  SP  T
Sbjct: 2053 TTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISA-----PSEG--SPLLT 2105

Query: 581  LEQMDFSAIDSNKDYTSSFSQT-GHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSG 639
               +  + + S +  T S +    +SP I  T       + +S P+P E  +  + + S 
Sbjct: 2106 SIPLSTTPVASPEASTLSTTPVDSNSPVITST-------EVSSSPIPTEGTSMQTSTYSD 2158

Query: 640  GTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAE 699
                + ++    +   SS    + T    TS+      +A     T+EG  +M TS  +E
Sbjct: 2159 RRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEG-TSMPTSTPSE 2217

Query: 700  GSEVLLKSGELQACSSEHYLQPETNGVIRSAGGVPILPGN-VVQGLYPVAQPSLGNASNM 758
            GS            S      P       +    P+     V       + P+    +++
Sbjct: 2218 GSTPF--------TSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSI 2269

Query: 759  ELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQLV-SGDSTALSQSEDGARAPF-TQ 816
              S      + S   + L          +S    H LV + + + LS +   +  PF T 
Sbjct: 2270 PTS------TLSEGTTPL----------TSIPVSHTLVANSEVSTLSTTPVDSNTPFTTS 2313

Query: 817  AEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDY 876
             E   P  + +  S+  S+S  G + +  M V+  + A+    TL           VT Y
Sbjct: 2314 TEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTST-PVTTY 2372

Query: 877  SPEWSYPEGGVKV-LITGPWQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTL 935
            S   S P       + T  + E S   +      SVP S +   V+      H T  V  
Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLT------SVPVSTMP--VVSSEASTHSTTPVDT 2424

Query: 936  QVAFNNQIISNSVVFEYKARALPTLPSSQ 964
                     ++S     +  ++PT P S+
Sbjct: 2425 STPVTTSTEASSSPTTAEGTSIPTSPPSE 2453



 Score = 38.1 bits (87), Expect = 0.072
 Identities = 82/395 (20%), Positives = 145/395 (36%), Gaps = 34/395 (8%)

Query: 510 SNIRHSPPGERSFSFTT--VLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSS 567
           +++  S P E S S T   V T  + + +         +  +    +  ASS   T  S+
Sbjct: 145 TDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPEST 204

Query: 568 LLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPV 627
            +P       ST L  M  S +       SS + T  +  +  +   +   Q +S P   
Sbjct: 205 TIPKSTNSEGSTPLTSMPASTMK----VASSEAITLLTTPVEISTPVTISAQASSSPTTA 260

Query: 628 EQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAE 687
           E  + S+ + SGG+  +  +        SS +  + T   +T+   +   +A+    TAE
Sbjct: 261 EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAE 320

Query: 688 GEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRSAGGVPILPGNVV-QGLYP 746
           G  ++ TS   EGS  L         S+     P     + +    P+    +V     P
Sbjct: 321 G-TSIPTSTYTEGSTPL--------TSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEP 371

Query: 747 VAQPSLGNASNMELSLDHFDISFSNQFSDLINDFIS-VEGGSSTIYGHQLVSGDS-TALS 804
            + P+   A++M  S      + S   + L N  +S +   SS       +  DS T ++
Sbjct: 372 SSLPTTAEATSMLTS------TLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVT 425

Query: 805 QSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGML 864
            + + + +P T  +  +   +P +GS  L+S          M V+    A+S    L   
Sbjct: 426 TASEASSSPTTAEDTSIATSTPSEGSTPLTS----------MPVSTTPVASSEASNLSTT 475

Query: 865 QQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEAS 899
               +  + T      S P   V  + T    E S
Sbjct: 476 PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGS 510


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 32/104 (30%), Positives = 58/104 (55%), Gaps = 11/104 (10%)

Query: 1527 AARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
            AA L+Q ++R +  R    +   AA VIQ+ +R Y     Y++   AAI IQ+++++Y E
Sbjct: 1077 AAALLQASWRAHLERQRYLELRAAAIVIQQKWRDY-----YRRRHMAAICIQARWKAYRE 1131

Query: 1587 QKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSS 1630
             K++Q+ R+  +L+Q   R +      R  +R   + +Q+LR +
Sbjct: 1132 SKRYQEQRKKIILLQSTCRGF------RARQRFKALKEQRLRET 1169



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 38/145 (26%), Positives = 71/145 (48%), Gaps = 14/145 (9%)

Query: 1516 LSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY------KQYALYKK 1569
            L D   +E+     L+Q  FR    R        A+ +IQR +R Y      +  A+ K 
Sbjct: 1011 LQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKD 1070

Query: 1570 ---MTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQK 1626
               M  AA L+Q+ +R++ E++++ + R AA++IQ+ +R Y      R+    A+ +Q +
Sbjct: 1071 AFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDY-----YRRRHMAAICIQAR 1125

Query: 1627 LRSSLLTKKQDQAARKIMRFLRRCR 1651
             ++   +K+  +  +KI+     CR
Sbjct: 1126 WKAYRESKRYQEQRKKIILLQSTCR 1150



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 1531 VQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKF 1590
            +Q  FRK    P   Q       ++   R++ Q  L++++ +  IL+Q  FR    ++ F
Sbjct: 980  IQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHF 1039

Query: 1591 QQSRRAAVLIQKYYRSYKKCGKRRQARRTAV 1621
               R+A+V+IQ+++R+Y     ++Q R  AV
Sbjct: 1040 LHLRQASVIIQRFWRNYL---NQKQVRDAAV 1067


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 6/124 (4%)

Query: 1538 YKGRPLREQQ-EVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRA 1596
            +K   LR+Q+ E  A +IQ+ YR +K    +  M ++ I+I + +R Y +QK++QQ++ +
Sbjct: 694  FKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753

Query: 1597 AVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLV 1656
            A++IQ Y R +K     R+ +      Q++ + ++ T        +  R LRR +     
Sbjct: 754  ALVIQSYIRGWKARKILRELKH-----QKRCKEAVTTIAAYWHGTQARRELRRLKEEARN 808

Query: 1657 DHRL 1660
             H +
Sbjct: 809  KHAI 812



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 13/144 (9%)

Query: 1481 EIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKG 1540
            E+ F +  +P      E+    +   + N      L D  ++ L + A L+Q  +R +K 
Sbjct: 665  EVLFNELEIPV----EEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKC 720

Query: 1541 RPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSY------YEQKKFQQSR 1594
            R      + +  VI   YR+Y Q   Y++   +A++IQS  R +       E K  ++ +
Sbjct: 721  RTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780

Query: 1595 RAAVLIQKYYRSYKKCGKRRQARR 1618
             A   I  Y+   +    RR+ RR
Sbjct: 781  EAVTTIAAYWHGTQ---ARRELRR 801


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 6/124 (4%)

Query: 1538 YKGRPLREQQ-EVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRA 1596
            +K   LR+Q+ E  A +IQ+ YR +K    +  M ++ I+I + +R Y +QK++QQ++ +
Sbjct: 694  FKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753

Query: 1597 AVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLV 1656
            A++IQ Y R +K     R+ +      Q++ + ++ T        +  R LRR +     
Sbjct: 754  ALVIQSYIRGWKARKILRELKH-----QKRCKEAVTTIAAYWHGTQARRELRRLKEEARN 808

Query: 1657 DHRL 1660
             H +
Sbjct: 809  KHAI 812



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 13/144 (9%)

Query: 1481 EIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKG 1540
            E+ F +  +P      E+    +   + N      L D  ++ L + A L+Q  +R +K 
Sbjct: 665  EVLFNELEIPV----EEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKC 720

Query: 1541 RPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSY------YEQKKFQQSR 1594
            R      + +  VI   YR+Y Q   Y++   +A++IQS  R +       E K  ++ +
Sbjct: 721  RTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780

Query: 1595 RAAVLIQKYYRSYKKCGKRRQARR 1618
             A   I  Y+   +    RR+ RR
Sbjct: 781  EAVTTIAAYWHGTQ---ARRELRR 801


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 26/72 (36%), Positives = 47/72 (65%), Gaps = 1/72 (1%)

Query: 1538 YKGRPLREQQ-EVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRA 1596
            +K   LR+Q+ E  A +IQ+ YR +K    +  M ++ I+I + +R Y +QK++QQ++ +
Sbjct: 694  FKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753

Query: 1597 AVLIQKYYRSYK 1608
            A++IQ Y R +K
Sbjct: 754  ALVIQSYIRGWK 765



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 16/159 (10%)

Query: 1481 EIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKG 1540
            E+ F +  +P      E+    +   + N      L D  ++ L + A L+Q  +R +K 
Sbjct: 665  EVLFNELEIPV----EEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKC 720

Query: 1541 RPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSY------YEQKKFQQSR 1594
            R      + +  VI   YR+Y Q   Y++   +A++IQS  R +       E K  ++ +
Sbjct: 721  RTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780

Query: 1595 RAAVLIQKYY------RSYKKCGKRRQARRTAVIVQQKL 1627
             A   I  Y+      R Y+K  +    ++      Q++
Sbjct: 781  EAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRI 819



 Score = 36.6 bits (83), Expect = 0.21
 Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 11/89 (12%)

Query: 1568 KKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKL 1627
            +++   A LIQ  +R +  +  F   +++ ++I  +YR Y +  + +Q + +A+++Q  +
Sbjct: 702  QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYI 761

Query: 1628 RSSLLTKKQDQAARKIMRFL---RRCRHS 1653
            R           ARKI+R L   +RC+ +
Sbjct: 762  RG--------WKARKILRELKHQKRCKEA 782


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQ--YALYKKMTQAAILIQSK 1580
            +L  A   +Q   R +  R    +   AA  +QR  R Y+   YA + + T+AA +IQ  
Sbjct: 765  KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824

Query: 1581 FRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARR--TAVIVQQKLRSSLLTKKQDQ 1638
            +R Y  +++++  R A +++Q Y R +    + R+  R   AVI+Q+++R  L      +
Sbjct: 825  WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884

Query: 1639 AARKIMRFLRRCRHSPLVDHRLYK 1662
            +   I+ +L+ C    +    L K
Sbjct: 885  SMHAII-YLQCCFRRMMAKRELKK 907



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 13/128 (10%)

Query: 1532 QTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQ---AAILIQSKFRSYYEQK 1588
            Q  F +Y  R L +Q++V +   Q C    ++  L K   Q     I  ++   +Y E+ 
Sbjct: 704  QEFFSRY--RVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKL 761

Query: 1589 KFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR 1648
            +  + R A + IQK  R +    K  + R+ A+ +Q+ +R           AR   +FLR
Sbjct: 762  RADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG--------YQARCYAKFLR 813

Query: 1649 RCRHSPLV 1656
            R + + ++
Sbjct: 814  RTKAATII 821


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQ--YALYKKMTQAAILIQSK 1580
            +L  A   +Q   R +  R    +   AA  +QR  R Y+   YA + + T+AA +IQ  
Sbjct: 765  KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824

Query: 1581 FRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARR--TAVIVQQKLRSSLLTKKQDQ 1638
            +R Y  +++++  R A +++Q Y R +    + R+  R   AVI+Q+++R  L      +
Sbjct: 825  WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKR 884

Query: 1639 AARKIMRFLRRCRHSPLVDHRLYK 1662
            +   I+ +L+ C    +    L K
Sbjct: 885  SMHAII-YLQCCFRRMMAKRELKK 907



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 13/128 (10%)

Query: 1532 QTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQ---AAILIQSKFRSYYEQK 1588
            Q  F +Y  R L +Q++V +   Q C    ++  L K   Q     I  ++   +Y E+ 
Sbjct: 704  QEFFSRY--RVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKL 761

Query: 1589 KFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR 1648
            +  + R A + IQK  R +    K  + R+ A+ +Q+ +R           AR   +FLR
Sbjct: 762  RADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG--------YQARCYAKFLR 813

Query: 1649 RCRHSPLV 1656
            R + + ++
Sbjct: 814  RTKAATII 821


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 7/132 (5%)

Query: 1510 EFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKK 1569
            E  +  L +   RE+     L+Q+ FR    R    Q + AA  IQ C+R Y+     ++
Sbjct: 942  ETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER 1001

Query: 1570 MTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRS 1629
             TQAA+ +Q+ +R Y+++K ++  +++ + +Q        C    Q +  + ++ +K ++
Sbjct: 1002 -TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSL------CRGHLQRKSFSQMISEKQKA 1054

Query: 1630 SLLTKKQDQAAR 1641
                ++  +AAR
Sbjct: 1055 EEKEREALEAAR 1066



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 5/124 (4%)

Query: 1530 LVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKK 1589
            ++ T   K K      Q       ++   R+  Q  L++++ +  +L+QS FR   E++ 
Sbjct: 916  VISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRH 975

Query: 1590 FQQSRRAAVLIQKYYRSYKKCGKRRQARRT--AVIVQQKLRSSLLTKKQDQAARKIMRFL 1647
            F Q +RAAV IQ  +RSY+    RR   RT  AV +Q   R     K      + I+R  
Sbjct: 976  FLQMKRAAVTIQACWRSYR---VRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQ 1032

Query: 1648 RRCR 1651
              CR
Sbjct: 1033 SLCR 1036


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 7/132 (5%)

Query: 1510 EFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKK 1569
            E  +  L +   RE+     L+Q+ FR    R    Q + AA  IQ C+R Y+     ++
Sbjct: 942  ETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER 1001

Query: 1570 MTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRS 1629
             TQAA+ +Q+ +R Y+++K ++  +++ + +Q        C    Q +  + ++ +K ++
Sbjct: 1002 -TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSL------CRGHLQRKSFSQMISEKQKA 1054

Query: 1630 SLLTKKQDQAAR 1641
                ++  +AAR
Sbjct: 1055 EEKEREALEAAR 1066



 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 5/124 (4%)

Query: 1530 LVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKK 1589
            ++ T   K K      Q       ++   R+  Q  L++++ +  +L+QS FR   E++ 
Sbjct: 916  VISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRH 975

Query: 1590 FQQSRRAAVLIQKYYRSYKKCGKRRQARRT--AVIVQQKLRSSLLTKKQDQAARKIMRFL 1647
            F Q +RAAV IQ  +RSY+    RR   RT  AV +Q   R     K      + I+R  
Sbjct: 976  FLQMKRAAVTIQACWRSYR---VRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQ 1032

Query: 1648 RRCR 1651
              CR
Sbjct: 1033 SLCR 1036


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 47.8 bits (112), Expect = 9e-05
 Identities = 87/407 (21%), Positives = 150/407 (36%), Gaps = 29/407 (7%)

Query: 318 SKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPV 377
           S G+S    +G       +  ++   SS     V   T S   + SSG+++  +   S V
Sbjct: 39  SSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTV 98

Query: 378 VTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSS 437
            +G+S +A  S   + S  A    S  TN    T S  A    +  S   S G   A +S
Sbjct: 99  SSGIS-IATNSESSTTSSGA----STATNSESSTPSSGASTATNSDSSTTSSGASTATNS 153

Query: 438 DGHKFAFPTTGSSESLSMLPTNV------SEELVLSTTLDGGRKIPETTMNFDPDCFLNN 491
           D    +   + ++ S S   ++       SE   +S+          +T +       N+
Sbjct: 154 DSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS 213

Query: 492 PKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTE-DTSFEQQMAKEAYSS 550
             +  + G G       S+    +     S S T        T  ++S     A  A +S
Sbjct: 214 ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273

Query: 551 SAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQ 610
            ++ V++   T+T   S  PS G  + + +      S  ++  +  SS + +G S   + 
Sbjct: 274 ESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNS 333

Query: 611 TPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTS 670
             S +      S       N+ SS + SG +    +  +  SS TS+ +    + + S +
Sbjct: 334 ESSTT------SSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387

Query: 671 SLHLMQFQANFQAMTAEGEVTMETSQAAEGSE-VLLKSGELQACSSE 716
           S           A T+E   T   +  A  SE   + SG   A +SE
Sbjct: 388 S----------TATTSESSTTSSGASTATNSESSTVSSGASTATNSE 424



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 55/248 (22%), Positives = 88/248 (35%), Gaps = 18/248 (7%)

Query: 344 SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
           SST        T S   + SSG  +  +   S   +G +G A  S   ++S      +S 
Sbjct: 230 SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSG-AGTATNSESSTVSSG----IST 284

Query: 404 VTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKF---AFPTTGSSESLSMLPTNV 460
           VTN    T S  A    +  S   S G   A +SD       A   T S  S +    + 
Sbjct: 285 VTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST 344

Query: 461 SEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGER 520
           +     STT  G      T  N       ++     T      ++  VSS    +   E 
Sbjct: 345 ATNSESSTTSSGA----STATNSG-----SSTTSSGTSTATNSESSTVSSGASTATTSES 395

Query: 521 SFSFTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTT 580
           S + +   T    +E ++     +    S S+   + ++    +GSS+  +G G +  T 
Sbjct: 396 STTSSGASTAT-NSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTG 454

Query: 581 LEQMDFSA 588
           +     SA
Sbjct: 455 MHTTSHSA 462


>gi|4885503 myosin IA [Homo sapiens]
          Length = 1043

 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 9/128 (7%)

Query: 1485 EKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHE----QRELYEAARLVQTAFRKYKG 1540
            E+  L S + W  + +    E VE    +L++S  E    + +++   R  +T F   + 
Sbjct: 636  ERYRLLSRSTWPHW-NGGDREGVEKVLGELSMSSGELAFGKTKIF--IRSPKTLFYLEEQ 692

Query: 1541 RPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLI 1600
            R LR QQ   A +IQ+ YR ++    Y+ M ++ ILI S FR   ++K + + + + +LI
Sbjct: 693  RRLRLQQ--LATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLI 750

Query: 1601 QKYYRSYK 1608
            Q + R +K
Sbjct: 751  QAFVRGWK 758



 Score = 32.7 bits (73), Expect = 3.0
 Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 1516 LSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAI 1575
            L +  +  L + A L+Q  +R ++ R   +    +  +I   +R   Q   Y K+  + +
Sbjct: 689  LEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVL 748

Query: 1576 LIQSKFRSYYEQK---KFQQSRRAAVLIQKYYRS 1606
            LIQ+  R +  +K   K+ +S  A  L    Y+S
Sbjct: 749  LIQAFVRGWKARKNYRKYFRSEAALTLADFIYKS 782


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 41/126 (32%), Positives = 57/126 (45%), Gaps = 20/126 (15%)

Query: 1065 GMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELE--VDPLNVDHFSCTPLMWACALGH 1122
            GMT L +AA +G              H D +DL LE   D  + D+   TPL+ A ++GH
Sbjct: 748  GMTPLLVAAYEG--------------HVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGH 793

Query: 1123 LEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECL--EHLQRDEQAQLGQNPRI 1180
                  L  W     SI DS GR  L IA ++G+V++   L    L  + +   G  P +
Sbjct: 794  ASVVNTLLFWGAAVDSI-DSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTP-L 851

Query: 1181 HCPASE 1186
            H  A E
Sbjct: 852  HMAAFE 857



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 67/325 (20%), Positives = 117/325 (36%), Gaps = 38/325 (11%)

Query: 1058 IHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTK-------------------HADSIDLE 1098
            + +    G T LH++  QG+  ++Q LI +                      H   + L 
Sbjct: 972  VEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLL 1031

Query: 1099 LEVDPLNVDHF---SCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRG 1155
            +E   + VDH      T L  A   GH++   VL +      +  D  GR  + +A   G
Sbjct: 1032 IEHGAV-VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADP-NHADQFGRTAMRVAAKNG 1089

Query: 1156 HVKLAECLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIA 1215
            H ++ + LE            +P +H    E+   +S  ++  S  I S     G T   
Sbjct: 1090 HSQIIKLLEKYGASSLNGCSPSP-VH--TMEQKPLQSLSSKVQSLTIKSNS--SGSTGGG 1144

Query: 1216 STNPELRRPRSEPSNYYS--SESHKDYPAPKKHKLNPEYFQTRQEKLLPTALSLEEPNIR 1273
               P LR   + P++ +S  SES       +K  L+    ++ +   L T  S       
Sbjct: 1145 DMQPSLRGLPNGPTHAFSSPSESPDSTVDRQKSSLSNNSLKSSKNSSLRTTSSTATAQTV 1204

Query: 1274 KQSPSSKQSVPETLSPSEGVRDFSRE-LSPPTPETAAFQASGSQPVGKWNSKDLYIGVST 1332
                    S  E +      R  SR+ +  P+  T +   S + P  ++    +   + +
Sbjct: 1205 PIDSFHNLSFTEQIQQHSLPRSRSRQSIVSPSSTTQSLGQSHNSPSSEFEWSQVKPSLKS 1264

Query: 1333 VQVT------GNPKGTSVGKEAAPS 1351
             + +       + K  S GK+A  S
Sbjct: 1265 TKASKGGKSENSAKSGSAGKKAKQS 1289



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 24/121 (19%)

Query: 1065 GMTLLHLAAAQGYATLIQTLIKWRTKHADSID----------------------LELEVD 1102
            G T L  AA+ G+A+++ TL+ W     DSID                      L+  +D
Sbjct: 781  GRTPLLAAASMGHASVVNTLLFWGAA-VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLD 839

Query: 1103 PLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAEC 1162
              + D    TPL  A   GH      L +   R   I D+ GR+P  +A   GH    + 
Sbjct: 840  ENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEI-DNDGRIPFILASQEGHYDCVQI 898

Query: 1163 L 1163
            L
Sbjct: 899  L 899


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 24/112 (21%)

Query: 1545 EQQEVAAAVIQRCYRKYKQYALYK-------------------KMTQAAILIQSKFRSYY 1585
            +++EV   V+ R  +   QY   K                   K+ Q+ +++Q   R + 
Sbjct: 712  DKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWL 771

Query: 1586 EQKKFQQSRRAAVLIQKYYRSYKKCGKRRQA-----RRTAVIVQQKLRSSLL 1632
            ++KKF + RRAA++IQ+Y+R  +   K   A        A+I+Q+  R  L+
Sbjct: 772  QRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLV 823



 Score = 39.3 bits (90), Expect = 0.032
 Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 6/128 (4%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQY-----ALYKKMTQAAILI 1577
            +L ++  +VQ   R +  R    ++  AA +IQ+ +R  +       A+  K   AAI+I
Sbjct: 755  KLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIII 814

Query: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSY-KKCGKRRQARRTAVIVQQKLRSSLLTKKQ 1636
            Q   R Y  +  +Q  R A + +Q Y R +  +   R+       ++ QK   + L +++
Sbjct: 815  QKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRR 874

Query: 1637 DQAARKIM 1644
             Q+ R+ +
Sbjct: 875  FQSIRRFV 882



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 1527 AARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQA--AILIQSKFRSY 1584
            AA ++Q   R Y  R L +   +A   +Q   R +     Y+KM +   A+++Q   R++
Sbjct: 810  AAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAW 869

Query: 1585 YEQKKFQQSRRAAVLIQKYYR 1605
              +++FQ  RR  + IQ  YR
Sbjct: 870  LARRRFQSIRRFVLNIQLTYR 890


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 57/204 (27%), Positives = 91/204 (44%), Gaps = 38/204 (18%)

Query: 1177 NPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSES 1236
            +P    P SEEP++ +        A+S+PE P   T  A+  P L  P S  +   + E 
Sbjct: 1217 SPAASVPTSEEPASLA-------AAVSNPEEP---TSPAAAVPTLEEPTSSAAAVLTPE- 1265

Query: 1237 HKDYPAPKKHKLNPEYFQTRQEKLLPTAL--SLEEPNIRKQSPSSKQSVPETLS-PSEGV 1293
              +  +P      PE      E   P A   +LEEP     SP++    PE  + P+  V
Sbjct: 1266 --ELSSPAASVPTPE------EPASPAAAVSNLEEP----ASPAAAVPTPEVAAIPAASV 1313

Query: 1294 RDFSRELSPPTPETAAFQASGSQPVGKWNSKDL-YIGVS--TVQVTGNPKGTSVGKEAAP 1350
                     PTPE  A  A+   P+ + +   + ++GVS  T  V  + +GT V +EA+ 
Sbjct: 1314 ---------PTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASS 1364

Query: 1351 SQVRPREPMSVLMMANREVVNTEL 1374
            + +  +E +  L+   +EV +T L
Sbjct: 1365 TGMWIKEDLDSLVFGIKEVTSTVL 1388


>gi|34304381 inversin isoform a [Homo sapiens]
          Length = 1065

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 1052 AKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSC 1111
            A ++ L++ + + G T LH A A G  T++  L  + + +  S D           +   
Sbjct: 208  APTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYD-----------NLFR 256

Query: 1112 TPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIA 1151
            TPL WA  LGH +   +L + ++      DS G  PL  A
Sbjct: 257  TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 16/122 (13%)

Query: 1065 GMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLE 1124
            G T LH AA  G+ + ++ L++      D+ D+              TPL  AC +GH +
Sbjct: 357  GGTALHAAALSGHVSTVKLLLE-NNAQVDATDV-----------MKHTPLFRACEMGHKD 404

Query: 1125 AAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECL--EHLQRDEQAQLGQNPRIHC 1182
                L K   R + + D  G   L  A   G+  + + L    +  + Q   G+ P + C
Sbjct: 405  VIQTLIKGGAR-VDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP-LQC 462

Query: 1183 PA 1184
             A
Sbjct: 463  AA 464


>gi|34304379 inversin isoform b [Homo sapiens]
          Length = 895

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 1052 AKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSC 1111
            A ++ L++ + + G T LH A A G  T++  L  + + +  S D           +   
Sbjct: 208  APTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYD-----------NLFR 256

Query: 1112 TPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIA 1151
            TPL WA  LGH +   +L + ++      DS G  PL  A
Sbjct: 257  TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 296



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 16/122 (13%)

Query: 1065 GMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLE 1124
            G T LH AA  G+ + ++ L++      D+ D+              TPL  AC +GH +
Sbjct: 357  GGTALHAAALSGHVSTVKLLLE-NNAQVDATDV-----------MKHTPLFRACEMGHKD 404

Query: 1125 AAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECL--EHLQRDEQAQLGQNPRIHC 1182
                L K   R + + D  G   L  A   G+  + + L    +  + Q   G+ P + C
Sbjct: 405  VIQTLIKGGAR-VDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP-LQC 462

Query: 1183 PA 1184
             A
Sbjct: 463  AA 464


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 2/85 (2%)

Query: 1568 KKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKL 1627
            K +T   IL+Q   R + ++  F + + AA LIQ+++R +  C K     R   +  Q L
Sbjct: 742  KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH-NCRKNYGLMRLGFLRLQAL 800

Query: 1628 -RSSLLTKKQDQAARKIMRFLRRCR 1651
             RS  L ++   A ++I++F  RCR
Sbjct: 801  HRSRKLHQQYRLARQRIIQFQARCR 825



 Score = 38.1 bits (87), Expect = 0.072
 Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 11/131 (8%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFR 1582
            +L  AA L+Q  +R +  R       +    +Q  +R  K +  Y+   Q  I  Q++ R
Sbjct: 766  KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCR 825

Query: 1583 SYYEQKKFQQSRRAAVLIQKYYRSY----------KKCGKRRQARRTAVIVQQKLRSSLL 1632
            +Y  +K F+    A + +Q Y R             +   R +A +  +  ++KLR  + 
Sbjct: 826  AYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMS 885

Query: 1633 TKK-QDQAARK 1642
             KK +++A RK
Sbjct: 886  AKKAKEEAERK 896



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/82 (28%), Positives = 43/82 (52%)

Query: 1553 VIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGK 1612
            ++Q+  R +K  + + K+  AA LIQ  +R +  +K +   R   + +Q  +RS K   +
Sbjct: 750  LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQ 809

Query: 1613 RRQARRTAVIVQQKLRSSLLTK 1634
             R AR+  +  Q + R+ L+ K
Sbjct: 810  YRLARQRIIQFQARCRAYLVRK 831


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 2/85 (2%)

Query: 1568 KKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKL 1627
            K +T   IL+Q   R + ++  F + + AA LIQ+++R +  C K     R   +  Q L
Sbjct: 742  KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH-NCRKNYGLMRLGFLRLQAL 800

Query: 1628 -RSSLLTKKQDQAARKIMRFLRRCR 1651
             RS  L ++   A ++I++F  RCR
Sbjct: 801  HRSRKLHQQYRLARQRIIQFQARCR 825



 Score = 38.1 bits (87), Expect = 0.072
 Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 11/131 (8%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFR 1582
            +L  AA L+Q  +R +  R       +    +Q  +R  K +  Y+   Q  I  Q++ R
Sbjct: 766  KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCR 825

Query: 1583 SYYEQKKFQQSRRAAVLIQKYYRSY----------KKCGKRRQARRTAVIVQQKLRSSLL 1632
            +Y  +K F+    A + +Q Y R             +   R +A +  +  ++KLR  + 
Sbjct: 826  AYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMS 885

Query: 1633 TKK-QDQAARK 1642
             KK +++A RK
Sbjct: 886  AKKAKEEAERK 896



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/82 (28%), Positives = 43/82 (52%)

Query: 1553 VIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGK 1612
            ++Q+  R +K  + + K+  AA LIQ  +R +  +K +   R   + +Q  +RS K   +
Sbjct: 750  LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQ 809

Query: 1613 RRQARRTAVIVQQKLRSSLLTK 1634
             R AR+  +  Q + R+ L+ K
Sbjct: 810  YRLARQRIIQFQARCRAYLVRK 831


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 2/85 (2%)

Query: 1568 KKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKL 1627
            K +T   IL+Q   R + ++  F + + AA LIQ+++R +  C K     R   +  Q L
Sbjct: 742  KAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH-NCRKNYGLMRLGFLRLQAL 800

Query: 1628 -RSSLLTKKQDQAARKIMRFLRRCR 1651
             RS  L ++   A ++I++F  RCR
Sbjct: 801  HRSRKLHQQYRLARQRIIQFQARCR 825



 Score = 38.1 bits (87), Expect = 0.072
 Identities = 32/131 (24%), Positives = 58/131 (44%), Gaps = 11/131 (8%)

Query: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFR 1582
            +L  AA L+Q  +R +  R       +    +Q  +R  K +  Y+   Q  I  Q++ R
Sbjct: 766  KLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCR 825

Query: 1583 SYYEQKKFQQSRRAAVLIQKYYRSY----------KKCGKRRQARRTAVIVQQKLRSSLL 1632
            +Y  +K F+    A + +Q Y R             +   R +A +  +  ++KLR  + 
Sbjct: 826  AYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMS 885

Query: 1633 TKK-QDQAARK 1642
             KK +++A RK
Sbjct: 886  AKKAKEEAERK 896



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/82 (28%), Positives = 43/82 (52%)

Query: 1553 VIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGK 1612
            ++Q+  R +K  + + K+  AA LIQ  +R +  +K +   R   + +Q  +RS K   +
Sbjct: 750  LLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQ 809

Query: 1613 RRQARRTAVIVQQKLRSSLLTK 1634
             R AR+  +  Q + R+ L+ K
Sbjct: 810  YRLARQRIIQFQARCRAYLVRK 831


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 1549 VAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYK 1608
            +AA  +QRC R +     ++ +    IL+QS+ R Y  ++++QQ RR+ V  +    +Y 
Sbjct: 1904 LAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYV 1963

Query: 1609 KCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIM 1644
                RR+  +     + ++  +LL ++++ + R+++
Sbjct: 1964 ---SRRRYLKLRAEWRCQVEGALLWEQEELSKREVV 1996


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 911

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 912  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1090

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1091 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 805  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 863  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 913

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 914  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1029 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSS 1167



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 55/364 (15%)

Query: 382 SGMAVASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPDASQGLVLAVSS 437
           S   VA   GS + +A+   SE T   +     T + TAG      SP  SQ  ++++S 
Sbjct: 3   SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS- 61

Query: 438 DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
            G +    +T  SE+ ++           S T        ETT++           +  T
Sbjct: 62  -GSEITTTSTAGSENTTVSSAG-------SGTTTASMAGSETTVS-------TAGSETTT 106

Query: 498 YGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAKEAYSSSAAAVA 556
               G +  MVS+    +     + S TTV  T   +T   S        AY++ +   A
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 557 ASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
           AS+         TAGS ++ PS  G   +T       +   S     ++ + T HS    
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS---- 222

Query: 610 QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
           +T + S    + +K                       V T  S  T S +G   T   + 
Sbjct: 223 ETTAASTMGSETTK-----------------------VSTAGSETTVSTAGSETTAASTE 259

Query: 670 SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRS 729
            S     F  + +  TA       T+ +  GSE  + S      +    + PET  V  +
Sbjct: 260 DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 730 AGGV 733
           +  V
Sbjct: 320 SSEV 323


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 911

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 912  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1090

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1091 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 805  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 863  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 913

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 914  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1029 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSS 1167



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 55/364 (15%)

Query: 382 SGMAVASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPDASQGLVLAVSS 437
           S   VA   GS + +A+   SE T   +     T + TAG      SP  SQ  ++++S 
Sbjct: 3   SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS- 61

Query: 438 DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
            G +    +T  SE+ ++           S T        ETT++           +  T
Sbjct: 62  -GSEITTTSTAGSENTTVSSAG-------SGTTTASMAGSETTVS-------TAGSETTT 106

Query: 498 YGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAKEAYSSSAAAVA 556
               G +  MVS+    +     + S TTV  T   +T   S        AY++ +   A
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 557 ASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
           AS+         TAGS ++ PS  G   +T       +   S     ++ + T HS    
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS---- 222

Query: 610 QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
           +T + S    + +K                       V T  S  T S +G   T   + 
Sbjct: 223 ETTAASTMGSETTK-----------------------VSTAGSETTVSTAGSETTAASTE 259

Query: 670 SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRS 729
            S     F  + +  TA       T+ +  GSE  + S      +    + PET  V  +
Sbjct: 260 DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 730 AGGV 733
           +  V
Sbjct: 320 SSEV 323


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 97/446 (21%), Positives = 154/446 (34%), Gaps = 82/446 (18%)

Query: 309  SEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNS 368
            S G    +H   SS    +G   K  + H S          +   TT SS  S +SG   
Sbjct: 2724 SPGSTPTTHFPASSTT--SGHSEKSTIFHSSP---------DASGTTPSSAHSTTSGRGE 2772

Query: 369  DPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS 428
                  SP  T ++ +  ++    LS+++T F S   +    T+SP +     + S    
Sbjct: 2773 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT-TLSPAS-----MTSLGVG 2826

Query: 429  QGLVLAVSSDG--HKFAFPTTGSSESLSMLPTNVSEELVLST-TLDGGRKIPETTMNFDP 485
            +    + S  G  H    P + ++  LS   T V      ST T    R    +    +P
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 486  DCFLNNPKQGQT------YGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSF 539
              F + P    T          GL  E  S+    SP   ++    T+ T ++  E T+F
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEE--STAFPGSPASTQTGLPATLTTADLGEESTTF 2944

Query: 540  EQQMAKEAYSSSAAAVAASSL----------------TLTAGSSLLPS------------ 571
                     + S A    S L                T   GS   PS            
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 3004

Query: 572  ---GGGLSPSTTL-----EQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASK 623
                  LSP+TT      E+   S       +T++F  +  +  + Q P+ S   Q +++
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTE 3064

Query: 624  -PLPVEQNTHSSLSDSGGTF---------------VMPTVKTEASSQTSSCSGHVETRI- 666
              L     T SSL     TF                + +   EAS+ T S +G + T + 
Sbjct: 3065 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 3124

Query: 667  -ESTSSLHLMQFQANFQAMTAEGEVT 691
              S++S  L +    FQ+  +  + T
Sbjct: 3125 PASSTSAGLQEESTTFQSWPSSSDTT 3150



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 97/446 (21%), Positives = 153/446 (34%), Gaps = 82/446 (18%)

Query: 309  SEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNS 368
            S G    +H   SS    +G   K  + H S          +   TT SS  S +SG   
Sbjct: 3807 SPGSTPTTHFPASSTT--SGHSEKSTIFHSSP---------DASGTTPSSAHSTTSGRGE 3855

Query: 369  DPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS 428
                  SP  T ++ +  ++    LS+++T F S   +    T+SP +     + S    
Sbjct: 3856 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT-TLSPAS-----MTSLGVG 3909

Query: 429  QGLVLAVSSDG--HKFAFPTTGSSESLSMLPTNVSEELVLST-TLDGGRKIPETTMNFDP 485
            +    + S  G  H    P + ++  LS   T V      ST T    R    +    +P
Sbjct: 3910 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEP 3969

Query: 486  DCFLNNPKQGQT------YGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSF 539
              F + P    T          GL  E  S+    SP   ++    T+ T ++  E T+F
Sbjct: 3970 TTFHSRPASTHTTLFTEDSTTSGLTEE--STAFPGSPASTQTGLPATLTTADLGEESTTF 4027

Query: 540  EQQMAKEAYSSSAAAVAASSL----------------TLTAGSSLLPS------------ 571
                       S A    S L                T   GS   PS            
Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 4087

Query: 572  ---GGGLSPSTTL-----EQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASK 623
                  LSP+TT      E+   S       +T++F  +  +  + Q P+ S   Q +++
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147

Query: 624  -PLPVEQNTHSSLSDSGGTF---------------VMPTVKTEASSQTSSCSGHVETRI- 666
              L     T SSL     TF                + +   EAS+ T S +G + T + 
Sbjct: 4148 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 4207

Query: 667  -ESTSSLHLMQFQANFQAMTAEGEVT 691
              S++S  L +    FQ+  +  + T
Sbjct: 4208 PASSTSTGLQEESTTFQSWPSSSDTT 4233



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 101/454 (22%), Positives = 156/454 (34%), Gaps = 98/454 (21%)

Query: 309  SEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNS 368
            S G    +H   SS    +G   K  + H S          +   TT SS  S +SG   
Sbjct: 1167 SPGSTPTTHFPASSTT--SGHSEKSTIFHSSP---------DASGTTPSSAHSTTSGRGE 1215

Query: 369  DPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS 428
                  SP  T ++ +  ++    LS+++T F S          SPT       LSP + 
Sbjct: 1216 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS-------PRSPTT-----TLSPASM 1263

Query: 429  QGLVLAVSSDGHKFAFPTTGSSESLSMLPT-NVSEELVLSTTLDGGRKIPETTM------ 481
              L +   S   +    +T S+ S +   T  +SEE   +T     R   ETT+      
Sbjct: 1264 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE--STTVYSSSRGSTETTVFPHSTT 1321

Query: 482  ----NFDPDCFLNNPKQGQT------YGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE 531
                  +P  F + P    T          GL  E  S+    SP   ++    T+ T +
Sbjct: 1322 TSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE--STAFPGSPASTQTGLPATLTTAD 1379

Query: 532  IKTEDTSFEQQMAKEAYSSSAAAVAASSL----------------TLTAGSSLLPS---- 571
            +  E T+F           S A    S L                T   GS   PS    
Sbjct: 1380 LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 1439

Query: 572  -----------GGGLSPSTTL-----EQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPS 615
                          LSP+TT      E+   S       +T++F  +  +  + Q P+ S
Sbjct: 1440 STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTS 1499

Query: 616  FFLQDASK-PLPVEQNTHSSLSDSGGTF---------------VMPTVKTEASSQTSSCS 659
               Q +++  L     T SSL     TF                + +   EAS+ T S +
Sbjct: 1500 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSST 1559

Query: 660  GHVETRI--ESTSSLHLMQFQANFQAMTAEGEVT 691
            G + T +   S++S  L +    FQ+  +  + T
Sbjct: 1560 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1593



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 94/426 (22%), Positives = 149/426 (34%), Gaps = 68/426 (15%)

Query: 309  SEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNS 368
            S G    +H   SS    +G   K  + H S          +   TT SS  S +SG   
Sbjct: 2250 SPGSTPTTHFPASSTT--SGHSEKSTIFHSSP---------DASGTTPSSAHSTTSGRGE 2298

Query: 369  DPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDAS 428
                  SP  T ++ +  ++    LS+++T F S   +    T+SP +     + S    
Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT-TLSPAS-----MTSLGVG 2352

Query: 429  QGLVLAVSSDG--HKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTM-NFDP 485
            +    + S  G  H    P + ++  LS   T V      ST      + P T++   +P
Sbjct: 2353 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412

Query: 486  DCFLNNPKQGQT------YGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKEIKTEDTSF 539
              F + P    T          GL  E  S+    SP   ++    T+ T ++  E T+F
Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLTEE--STAFPGSPASTQTGLPATLTTADLGEESTTF 2470

Query: 540  EQQMAKEAYSSSAAAVAASSL----------------TLTAGSSLLPS---------GGG 574
                     + S A    S L                T   GS   PS            
Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 2530

Query: 575  LSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNT--H 632
             SP  TL     ++   +++ ++S SQ G +   H T  P       + P     +T  H
Sbjct: 2531 RSPDATLSPATTTSSGVSEESSTSHSQPGST---HTTAFP----DSTTTPGLSRHSTTSH 2583

Query: 633  SSLSDSGGTFVMPTVKTEASSQTSSCS----GHVETRIE--STSSLHLMQFQANFQAMTA 686
            SS   +  T +  +  T   SQ S+ S    G  +T +   ST++L   Q    F +   
Sbjct: 2584 SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG 2643

Query: 687  EGEVTM 692
                T+
Sbjct: 2644 STHTTL 2649



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 128/650 (19%), Positives = 212/650 (32%), Gaps = 69/650 (10%)

Query: 288  PKVEPRTGGYGSHSEVQHNDVSEGKHEHSHSKGSS----REKRNGKVAKPVLLHQSSTEV 343
            P   P T    S + +  ++ S   H    + G++    R   +  V +P     SS   
Sbjct: 4254 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISS--- 4310

Query: 344  SSTNQVEVPDTTQSSPVSISS----GLNSDPDMVDSPVVTGVSGMAVASVMGSL---SQS 396
             ST    +P +T ++ +S  S         PD   SP  T  SG++  S        S  
Sbjct: 4311 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMH 4370

Query: 397  ATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSML 456
             T F S  T   V   S  +  +        S G   A S       F ++  S   ++L
Sbjct: 4371 TTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 4430

Query: 457  PTNVSEE--LVLSTTLDGGRKIPETTMN--------FDPDCFLNNPKQGQTYGG--GGLK 504
            P N +    L  ST +      P TT++         +   F + P    T         
Sbjct: 4431 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 4490

Query: 505  AEMVSSNIRHSPPGE--------------RSFSFTTVLTKEIKTEDTSFEQQMAKEAY-- 548
            A +  S   H  P                RS   TTV +  + T  T    +        
Sbjct: 4491 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 4550

Query: 549  -SSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPH 607
             S++  +   S+ T+    S   SG G   STT        I S    TS+  +   S H
Sbjct: 4551 ESTTYHSSPGSTQTMHFPESNTTSGRG-EESTTSHSSTTHTISSAPSTTSALVEEPTSYH 4609

Query: 608  IHQTPSPSFFLQDAS--KPLPVEQNTHSSLSDSGGTFVMPTVKTEA-----SSQTSSCSG 660
                 + +    D+S       E     S  D+ GT V+P   T +     S+ +   SG
Sbjct: 4610 SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 4669

Query: 661  HVETRI--ESTSSLHLMQFQANFQAMTAEGEVT----METSQAAEGSEVLLKSGELQACS 714
             +ET     ST++  L +    F +  +    T      T+         + S  +   +
Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 4729

Query: 715  SEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMEL---SLDHFDISFSN 771
            +    +  T+G++  +      PG+     +P +  + G +        S  H   S  +
Sbjct: 4730 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 4789

Query: 772  QFSDLINDFISVEGGSSTIYGHQLVSGDSTALSQSEDGA--RAPFTQAEMCLPCCSPQQG 829
              S L+ +  S      +I         +T+    E  A   +P T     LP      G
Sbjct: 4790 TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 4849

Query: 830  SLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPE 879
             +         ST  Y+    + +  ++  T   L     +   +  SP+
Sbjct: 4850 RI-------AESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 4892



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 82/350 (23%), Positives = 120/350 (34%), Gaps = 48/350 (13%)

Query: 328  GKVAKPVLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDS-PVVTGVSGMAV 386
            G      L  +S+T  SS      PDTT S   + SSG++ +     S P  T  +    
Sbjct: 1680 GSTTTAGLSEKSTTFYSSPRS---PDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 1736

Query: 387  ASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPT 446
            ++ M  +SQ +T   S            + G     LSP    G   A S       F +
Sbjct: 1737 STTMPGVSQESTASHS------------SPGSTDTTLSP----GSTTASSLGPESTTFHS 1780

Query: 447  TGSSESLSMLPTNVSEE--LVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLK 504
            +  S   ++LP N +    L  ST +      P TT++  P        +  T+     +
Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS--PAGSTTRQGESTTF-----Q 1833

Query: 505  AEMVSSNIRHSPPGERSFSF---TTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSL- 560
            +   S +   +PP   S      TT       T  T F         S  +  V +S + 
Sbjct: 1834 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 1893

Query: 561  TLTAGSSLLPSGGGL---------SPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT 611
            T T  S    +  GL         SP +T + M F    S     S  S+T HS   H  
Sbjct: 1894 TATTPSPARSTTSGLVEESTAYHSSPGST-QTMHFPE-SSTASGRSEESRTSHSSTTHTI 1951

Query: 612  PSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGH 661
             SP       +  L  E  ++ S   S  T   P   T +     S + H
Sbjct: 1952 SSP----PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 1997


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 911

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 912  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1090

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1091 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 805  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 863  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 913

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 914  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1029 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSS 1167



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 55/364 (15%)

Query: 382 SGMAVASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPDASQGLVLAVSS 437
           S   VA   GS + +A+   SE T   +     T + TAG      SP  SQ  ++++S 
Sbjct: 3   SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS- 61

Query: 438 DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
            G +    +T  SE+ ++           S T        ETT++           +  T
Sbjct: 62  -GSEITTTSTAGSENTTVSSAG-------SGTTTASMAGSETTVS-------TAGSETTT 106

Query: 498 YGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAKEAYSSSAAAVA 556
               G +  MVS+    +     + S TTV  T   +T   S        AY++ +   A
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 557 ASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
           AS+         TAGS ++ PS  G   +T       +   S     ++ + T HS    
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS---- 222

Query: 610 QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
           +T + S    + +K                       V T  S  T S +G   T   + 
Sbjct: 223 ETTAASTMGSETTK-----------------------VSTAGSETTVSTAGSETTAASTE 259

Query: 670 SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRS 729
            S     F  + +  TA       T+ +  GSE  + S      +    + PET  V  +
Sbjct: 260 DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 730 AGGV 733
           +  V
Sbjct: 320 SSEV 323


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 753  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 812

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 813  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 873  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 932

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 933  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 992

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 993  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1052

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1053 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1111

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1112 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1143



 Score = 37.7 bits (86), Expect = 0.094
 Identities = 82/375 (21%), Positives = 130/375 (34%), Gaps = 58/375 (15%)

Query: 374 DSPVVTGVSGMA---VASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPD 426
           DS V+T  S  +   VA   GS + +A+   SE T   +     T + TAG      SP 
Sbjct: 13  DSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPT 72

Query: 427 ASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPD 486
            SQ  ++++S  G +    +T  SE+              +T    G      +M     
Sbjct: 73  GSQTTIVSIS--GSEITTTSTAGSEN--------------TTVSSAGSGTTTASMAGSES 116

Query: 487 CFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAK 545
                  +  T    G +  MVS+    +     + S TTV  T   +T   S       
Sbjct: 117 TISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETT 176

Query: 546 EAYSSSAAAVAASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSS 598
            AY++ +   AAS+         TAGS ++ PS  G   +T       +   S     ++
Sbjct: 177 TAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETT 236

Query: 599 FSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSC 658
            + T HS    +T + S    + +K                       V T  S  T S 
Sbjct: 237 TASTAHS----ETTAASTMGSETTK-----------------------VSTAGSETTVST 269

Query: 659 SGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHY 718
           +G   T   +  S     F  + +  TA       T+ +  GSE  + S      +    
Sbjct: 270 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 329

Query: 719 LQPETNGVIRSAGGV 733
           + PET  V  ++  V
Sbjct: 330 IGPETTKVSTASSEV 344



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 826  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 883

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 884  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 934

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 935  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 992

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 993  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1049

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1050 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1105

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1106 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1165

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1166 TVFTTVSETTTVSTIGSEATTSS 1188


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 911

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 912  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1090

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1091 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 805  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 863  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 913

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 914  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1029 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSS 1167



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 55/364 (15%)

Query: 382 SGMAVASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPDASQGLVLAVSS 437
           S   VA   GS + +A+   SE T   +     T + TAG      SP  SQ  ++++S 
Sbjct: 3   SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS- 61

Query: 438 DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
            G +    +T  SE+ ++           S T        ETT++           +  T
Sbjct: 62  -GSEITTTSTAGSENTTVSSAG-------SGTTTASMAGSETTVS-------TAGSETTT 106

Query: 498 YGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAKEAYSSSAAAVA 556
               G +  MVS+    +     + S TTV  T   +T   S        AY++ +   A
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 557 ASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
           AS+         TAGS ++ PS  G   +T       +   S     ++ + T HS    
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS---- 222

Query: 610 QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
           +T + S    + +K                       V T  S  T S +G   T   + 
Sbjct: 223 ETTAASTMGSETTK-----------------------VSTAGSETTVSTAGSETTAASTE 259

Query: 670 SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRS 729
            S     F  + +  TA       T+ +  GSE  + S      +    + PET  V  +
Sbjct: 260 DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 730 AGGV 733
           +  V
Sbjct: 320 SSEV 323


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 83/397 (20%), Positives = 137/397 (34%), Gaps = 44/397 (11%)

Query: 344  SSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSE 403
            ++T   E  +TT +S     +   S      +   T  S   +AS+MGS +  A+   SE
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 404  VT--NEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESLSMLPTNVS 461
             T  + A   M+     N        +      VS+ G +    +T  SE+ +   T  S
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 462  EELVLST------------------TLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGL 503
            E    ST                  T  G      +T   +         +  T    G 
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGS 911

Query: 504  KAEMVSSNIRHSPPGERSFSFTTVLT---KEIKTEDTSFEQQMAKEAYSSSAAAV----A 556
            +   VS+    +       S TT  +    E+ T  T+  + +   A  S    V    +
Sbjct: 912  EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 557  ASSLTLTAGS--SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQT--P 612
             ++   TAGS  + + + G  + + ++E  + + + S    T++ S TG    I  T   
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGS 1031

Query: 613  SPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSL 672
              +      S+   V      + + S       TV T  S  T++ +  +ET   STS  
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG- 1090

Query: 673  HLMQFQANFQAMTAEGEVT-------METSQAAEGSE 702
                      A TA  E T         T+ + EGSE
Sbjct: 1091 -----SGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 29/383 (7%)

Query: 334  VLLHQSSTEVSSTNQVEVPDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSL 393
            V    S T ++ST   E   TT S+  S +   ++      +   T  S    AS  GS 
Sbjct: 805  VFTENSETTIASTTASET--TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 394  SQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHKFAFPTTGSSESL 453
            + +A+   SE T       + T G      S + S+      S++G +    +T  SE +
Sbjct: 863  TTTASTESSETTT------ATTIGSETTTASTEGSE--TTTTSTEGSETTTASTEGSE-I 913

Query: 454  SMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIR 513
            + + T  SE    ST  +G      +T   +         +  T    G +   V++   
Sbjct: 914  TTVSTTGSETTTAST--EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 514  HSPPGERSFS-FTTVLTKEIKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSG 572
             +     + S  TTV T   +T   S E     E  + S+     ++++ T   + + S 
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 573  GGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDASKPLPVEQNTH 632
             G S +TT+     +  ++   YT+    T  S    +T + S    + +     +  T 
Sbjct: 1029 EG-SETTTVTT---AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 633  SSLSDSGGTFVMPTVKTEASS--------QTSSCSGHVETRIESTSSLHLMQFQANFQAM 684
            +  +   GT    T  +E ++         T+S  G   T + +TSS          +  
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 685  TAEGEVTMETSQAAEGSEVLLKS 707
            T    V+  T+ +  GSE    S
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSS 1167



 Score = 36.2 bits (82), Expect = 0.27
 Identities = 80/364 (21%), Positives = 128/364 (35%), Gaps = 55/364 (15%)

Query: 382 SGMAVASVMGSLSQSATVFMSEVTNEAVY----TMSPTAGPNHHLLSPDASQGLVLAVSS 437
           S   VA   GS + +A+   SE T   +     T + TAG      SP  SQ  ++++S 
Sbjct: 3   SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS- 61

Query: 438 DGHKFAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQT 497
            G +    +T  SE+ ++           S T        ETT++           +  T
Sbjct: 62  -GSEITTTSTAGSENTTVSSAG-------SGTTTASMAGSETTVS-------TAGSETTT 106

Query: 498 YGGGGLKAEMVSSNIRHSPPGERSFSFTTVL-TKEIKTEDTSFEQQMAKEAYSSSAAAVA 556
               G +  MVS+    +     + S TTV  T   +T   S        AY++ +   A
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 557 ASSL------TLTAGS-SLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIH 609
           AS+         TAGS ++ PS  G   +T       +   S     ++ + T HS    
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHS---- 222

Query: 610 QTPSPSFFLQDASKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIEST 669
           +T + S    + +K                       V T  S  T S +G   T   + 
Sbjct: 223 ETTAASTMGSETTK-----------------------VSTAGSETTVSTAGSETTAASTE 259

Query: 670 SSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQACSSEHYLQPETNGVIRS 729
            S     F  + +  TA       T+ +  GSE  + S      +    + PET  V  +
Sbjct: 260 DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 730 AGGV 733
           +  V
Sbjct: 320 SSEV 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,823,233
Number of Sequences: 37866
Number of extensions: 3220377
Number of successful extensions: 16304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 227
Number of HSP's that attempted gapping in prelim test: 13460
Number of HSP's gapped (non-prelim): 2481
length of query: 1673
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1557
effective length of database: 13,855,062
effective search space: 21572331534
effective search space used: 21572331534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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