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Search of human proteins with 54112382
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
[Homo sapiens]
(1336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 2758 0.0
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 2544 0.0
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 823 0.0
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 508 e-143
gi|32698700 PHD finger protein 8 [Homo sapiens] 291 3e-78
gi|90093355 jumonji C domain containing histone demethylase 1 ho... 274 4e-73
gi|117190342 PHD finger protein 2 [Homo sapiens] 248 4e-65
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 78 6e-14
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 71 8e-12
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens] 67 1e-10
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens] 67 1e-10
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 65 4e-10
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 62 4e-09
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 62 4e-09
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 60 2e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 60 2e-08
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 58 5e-08
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 58 7e-08
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 58 7e-08
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 57 9e-08
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 55 5e-07
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 55 5e-07
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 55 5e-07
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 55 6e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 6e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 50 1e-05
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 49 2e-05
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 49 3e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 48 6e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 47 9e-05
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 2758 bits (7148), Expect = 0.0
Identities = 1336/1336 (100%), Positives = 1336/1336 (100%)
Query: 1 MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQRPIDRQRYDENEDLSDVE 60
MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQRPIDRQRYDENEDLSDVE
Sbjct: 1 MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQRPIDRQRYDENEDLSDVE 60
Query: 61 EIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPD 120
EIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPD
Sbjct: 61 EIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPD 120
Query: 121 PDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSH 180
PDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSH
Sbjct: 121 PDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSH 180
Query: 181 TKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTD 240
TKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTD
Sbjct: 181 TKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTD 240
Query: 241 FHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIEL 300
FHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIEL
Sbjct: 241 FHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIEL 300
Query: 301 KQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYY 360
KQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYY
Sbjct: 301 KQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYY 360
Query: 361 EMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQ 420
EMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQ
Sbjct: 361 EMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQ 420
Query: 421 EEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEES 480
EEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEES
Sbjct: 421 EEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEES 480
Query: 481 VKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIED 540
VKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIED
Sbjct: 481 VKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIED 540
Query: 541 PQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAAN 600
PQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAAN
Sbjct: 541 PQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAAN 600
Query: 601 RTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTA 660
RTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTA
Sbjct: 601 RTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTA 660
Query: 661 VCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECP 720
VCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECP
Sbjct: 661 VCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECP 720
Query: 721 KCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDE 780
KCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDE
Sbjct: 721 KCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDE 780
Query: 781 HSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSS 840
HSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSS
Sbjct: 781 HSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSS 840
Query: 841 LSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEA 900
LSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEA
Sbjct: 841 LSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEA 900
Query: 901 PPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQR 960
PPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQR
Sbjct: 901 PPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQR 960
Query: 961 TENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPP 1020
TENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPP
Sbjct: 961 TENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPP 1020
Query: 1021 RVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQ 1080
RVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQ
Sbjct: 1021 RVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQ 1080
Query: 1081 DLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQ 1140
DLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQ
Sbjct: 1081 DLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQ 1140
Query: 1141 LSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTD 1200
LSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTD
Sbjct: 1141 LSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTD 1200
Query: 1201 NRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1260
NRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT
Sbjct: 1201 NRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1260
Query: 1261 AVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSV 1320
AVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSV
Sbjct: 1261 AVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSV 1320
Query: 1321 SVQFGQVEEKLLQKLS 1336
SVQFGQVEEKLLQKLS
Sbjct: 1321 SVQFGQVEEKLLQKLS 1336
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 2544 bits (6593), Expect = 0.0
Identities = 1239/1277 (97%), Positives = 1239/1277 (97%), Gaps = 38/1277 (2%)
Query: 43 RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL 102
RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL
Sbjct: 12 RPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREAL 71
Query: 103 RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET 162
RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET
Sbjct: 72 RVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYET 131
Query: 163 PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK 222
PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK
Sbjct: 132 PEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMK 191
Query: 223 YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK 282
YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK
Sbjct: 192 YPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGK 251
Query: 283 QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY 342
QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY
Sbjct: 252 QSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIY 311
Query: 343 EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF 402
EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF
Sbjct: 312 EIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGF 371
Query: 403 SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK 462
SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK
Sbjct: 372 SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK 431
Query: 463 APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE 522
APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE
Sbjct: 432 APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVE 491
Query: 523 KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV 582
KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV
Sbjct: 492 KLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAV 551
Query: 583 GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM 642
GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM
Sbjct: 552 GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM 611
Query: 643 KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI 702
KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI
Sbjct: 612 KQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKI 671
Query: 703 KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE 762
KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE
Sbjct: 672 KESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE 731
Query: 763 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQ 822
PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKR
Sbjct: 732 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKR----- 786
Query: 823 TSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALA 882
LKPGKEDKLFRKKRRSWKNAEDRMALA
Sbjct: 787 ---------------------------------LKPGKEDKLFRKKRRSWKNAEDRMALA 813
Query: 883 NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP 942
NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP
Sbjct: 814 NKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLP 873
Query: 943 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 1002
NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN
Sbjct: 874 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 933
Query: 1003 GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA 1062
GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA
Sbjct: 934 GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAA 993
Query: 1063 HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII 1122
HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII
Sbjct: 994 HVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGII 1053
Query: 1123 RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW 1182
RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW
Sbjct: 1054 RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQW 1113
Query: 1183 VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK 1242
VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK
Sbjct: 1114 VEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSK 1173
Query: 1243 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY 1302
LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY
Sbjct: 1174 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRY 1233
Query: 1303 CKQVTKEGCEQFIAEMS 1319
CKQVTKEGCEQFIAEMS
Sbjct: 1234 CKQVTKEGCEQFIAEMS 1250
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 823 bits (2125), Expect = 0.0
Identities = 415/702 (59%), Positives = 513/702 (73%), Gaps = 48/702 (6%)
Query: 47 RQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPL 106
R+RY E++ +SD +EI R F LEEKL + Y +FV MEGKDFN EY+QR LR PL
Sbjct: 19 RRRY-EDDGISD-DEIEGKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPL 76
Query: 107 IFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQ 166
IF+ DGLGIKMPDPDFTV DVK+ VGSRR+VDVMDVNTQKG EM+M+Q+ RYYETPE +
Sbjct: 77 IFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEE 136
Query: 167 RDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKV 226
R+KLYNVISLEFSHT+LE++V+RP+ VD +DWVDNMWP+HLKE QTE+TNAI EM+YPKV
Sbjct: 137 REKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKV 196
Query: 227 KKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDI 286
+KYCLMSV+GC+TDFH+DFGGTSVWYH+ +GGK+FWLIPPT HNL LYE W+LSGKQ DI
Sbjct: 197 QKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDI 256
Query: 287 FLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIED 346
FLGDRV CQRIELKQGYTF IPSGWIHAVYTP D+LVFGGN LHSFN+PMQL+IY IED
Sbjct: 257 FLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIED 316
Query: 347 RTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDS 406
RTRV KFRYPFYYEMCWYVLERYVYC+T RSHLT+E+Q+ES+ +D ++G S +
Sbjct: 317 RTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDL----ELNGLESGN 372
Query: 407 WLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPAL 466
+EEA D++P+ + R P +G + D + LGK + +L
Sbjct: 373 G---DEEAVDREPRRLSSR------RSVLTSPVANG-------VNLDYDGLGKTCR--SL 414
Query: 467 RFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLES 526
LK+TL+ +S S P +P + + HLT FEL+GL+ LV+KLES
Sbjct: 415 PSLKKTLAGDSSSDC-SRGSHNGQVWDPQCAPRKD---RQVHLTHFELEGLRCLVDKLES 470
Query: 527 LPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKK-------TPKN 579
LP +KKCVP GIED AL+ VK +L+E A+ DP LA+TGVP+V WPK+ PK
Sbjct: 471 LPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLALTGVPIVQWPKRDKLKFPTRPKV 530
Query: 580 RAVGRPKGK---LGPASAV----KLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKD 632
R P K + PA + AA+ +GARRRR RCRKC+AC++ ECG CH+C+D
Sbjct: 531 RVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRD 590
Query: 633 MKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICN 692
MKKFGGPGRMKQSC++RQC+AP LPH+ C +CGE + + ++ E K LMEC ICN
Sbjct: 591 MKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKK----LMECCICN 646
Query: 693 EIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGK-QKR 733
EI+HPGCL++ + EG++N+ELPNCWECPKC + K QKR
Sbjct: 647 EIVHPGCLQM-DGEGLLNEELPNCWECPKCYQEDSSEKAQKR 687
Score = 405 bits (1041), Expect = e-112
Identities = 235/508 (46%), Positives = 320/508 (62%), Gaps = 53/508 (10%)
Query: 860 KEDKLFRKKRRSWKNAEDRMALAN--KPLRRFKQEPEDELPEAPPKTRESDHS------- 910
+ED + ++R + +++ A +PLR EP P +P + H
Sbjct: 677 QEDSSEKAQKRKMEESDEEAVQAKVLRPLRSC-DEPLTPPPHSPTSMLQLIHDPVSPRGM 735
Query: 911 -RSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANEN 969
SSP AGPS + +E+ K ++L R +Q TE ++ E
Sbjct: 736 VTRSSPGAGPSDHHSASRDERFK----------RRQLLR---------LQATERTMVREK 776
Query: 970 QQPIKSEPE-SEGEEPK-RPPGICERPHRFSKGLNGTPRELRHQL----GPSLRSPPRVI 1023
+ + E SE E+ K R + R +K L+GT + Q +LR PRV+
Sbjct: 777 ENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRHSPRVL 836
Query: 1024 SRPPPSVSPPKCIQM--------ERHVIRPPPISPPPDSLPLD-------DGAAHVMHRE 1068
+ P+ +P + + E + + L+ DG M RE
Sbjct: 837 VQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQRE 896
Query: 1069 VWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVS 1128
VWM+VF YLS ++LC CMRVC+TW +WCCDKRLWT+IDL+ CK+I P LSGII+RQPVS
Sbjct: 897 VWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVS 956
Query: 1129 LDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKD 1188
LDLSWTNISKKQL+WL+NRLPGL+DL+L+GCSW AVSAL +SSCPLLRTLD++W G+KD
Sbjct: 957 LDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKD 1016
Query: 1189 AQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYC 1248
Q+RDLL+PP D +PGQ DNRSKLRN+ + RLAGLDITDA+LRLIIRHMPLLS+L LS+C
Sbjct: 1017 PQIRDLLTPPAD-KPGQ-DNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHC 1074
Query: 1249 NHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTK 1308
+H+TDQS NLLTAVG++TR SLTE+N++ CNK+TDQ L + +R N+ IDLR CKQ+T+
Sbjct: 1075 SHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITR 1134
Query: 1309 EGCEQFIAEMSVSVQFGQVEEKLLQKLS 1336
+ CE FI+++S++ + +EKL+QK+S
Sbjct: 1135 KACEHFISDLSINSLYCLSDEKLIQKIS 1162
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens]
Length = 694
Score = 508 bits (1307), Expect = e-143
Identities = 304/770 (39%), Positives = 414/770 (53%), Gaps = 106/770 (13%)
Query: 586 KGKLGPASAVKLAANRTT----AGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGR 641
KG+ GP++ + + ++ AGARRRRTRCR+C AC+RTECG+CHFC+DMKKFGGPGR
Sbjct: 8 KGESGPSALLTPPMSSSSRGPGAGARRRRTRCRRCRACVRTECGDCHFCRDMKKFGGPGR 67
Query: 642 MKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLK 701
MKQSC++RQC APVLPHTAVCL+CGEAGKEDTVE EE KF L LM
Sbjct: 68 MKQSCLLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLM--------------- 112
Query: 702 IKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQ 761
EC CN G K G EG
Sbjct: 113 ----------------ECTICNEIVHPGCLKMGKA----------------------EGV 134
Query: 762 EPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDD------VHLRKKRKYEKPQELSGR 815
A+ + C E PR + + K +G RR++D+ + K E P
Sbjct: 135 INAEIPN-CWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLGSGWKLTEEPPLPPPPP 193
Query: 816 KRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNA 875
+R L P P PP +++ + G E RKK + +
Sbjct: 194 RRKGPLPAGPPPED--VPGPPK---------------RKEREAGNEPPTPRKKVKGGRER 236
Query: 876 EDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTA---------GPSTEGAEG 926
+ + L R L PP+ + SS P AEG
Sbjct: 237 HLKKVGGDACLLRGSDPGGPGL--LPPRVLNPSQAFSSCHPGLPPENWEKPKPPLASAEG 294
Query: 927 PEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKR 986
P R K E K + ++R ++ ++ + S+
Sbjct: 295 PAVPSPSPQREKL---------ERFKRMCQLLERVPDTSSSSSDSDSDSDSSGTSLSEDE 345
Query: 987 PPGICERPHRFSKGLNGTP--RELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIR 1044
PG R ++G +G R R + P P ++S P PP+ Q+ERHV+R
Sbjct: 346 APGEARNGRRPARGSSGEKENRGGRRAVRPGSGGP--LLSWPLGPAPPPRPPQLERHVVR 403
Query: 1045 PPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTR 1104
PPP SP PD+LPL G+ H + R W+ VF +L ++LC+CMRVCRTW+RWC DKRLW R
Sbjct: 404 PPPRSPEPDTLPLAAGSDHPLPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPR 463
Query: 1105 IDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAV 1164
+DL+ KS+TP MLSG++RRQP +LDLSWT +SKKQL WL+NRL GL++LVLSGCSW++V
Sbjct: 464 MDLSRRKSLTPPMLSGVVRRQPRALDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSV 523
Query: 1165 SALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD 1224
SAL S+ P LR LD++W+E +KD+Q+R+LL PP D +PGQ ++R +L+ + ELRLAGL+
Sbjct: 524 SALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLE 583
Query: 1225 ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ 1284
+TDASLRL++RH P LS L LS+C HV D S++LLTA + R++L +NL+ C+++TD
Sbjct: 584 LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDH 643
Query: 1285 CLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQK 1334
CL F+RC + +DLR C+Q++ E C + +A F EEKLL K
Sbjct: 644 CLPLFRRCPRLRRLDLRSCRQLSPEACAR-LAAAGPPGPFRCPEEKLLLK 692
>gi|32698700 PHD finger protein 8 [Homo sapiens]
Length = 1024
Score = 291 bits (745), Expect = 3e-78
Identities = 140/296 (47%), Positives = 194/296 (65%), Gaps = 16/296 (5%)
Query: 73 KLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKL 130
+LRS+ + + + G E+++ + VP++ +KDGLG+ +P P FTVRDV+
Sbjct: 90 ELRSRTFDSSDEVILKPTGNQLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEH 149
Query: 131 LVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRP 190
VGS + +DV+DV Q +M + FV+YY + +R+K+ NVISLEFS T+L +LV+ P
Sbjct: 150 YVGSDKEIDVIDVTRQADCKMKLGDFVKYYYS--GKREKVLNVISLEFSDTRLSNLVETP 207
Query: 191 TVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSV 250
+V + WV+N+WP+ + P V+KYCLMSV+ +TDFHIDFGGTSV
Sbjct: 208 KIVRKLSWVENLWPEE------------CVFERPNVQKYCLMSVRDSYTDFHIDFGGTSV 255
Query: 251 WYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPS 310
WYHV +G KIF+LI PT NL L+E W S Q+++F GD+V++C + +KQG T FIP+
Sbjct: 256 WYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQNEMFFGDQVDKCYKCSVKQGQTLFIPT 315
Query: 311 GWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 366
GWIHAV TPVD L FGGN LHS N+ MQL+ YEIE R FR+P + +CWYV
Sbjct: 316 GWIHAVLTPVDCLAFGGNFLHSLNIEMQLKAYEIEKRLSTADLFRFPNFETICWYV 371
Score = 31.2 bits (69), Expect = 7.0
Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 685 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN--HAGKTGKQKRG 734
++EC +C + H C+ ++E + D + CP C H K++RG
Sbjct: 20 MIECDMCQDWFHGSCVGVEEEKAADID----LYHCPNCEVLHGPSIMKKRRG 67
>gi|90093355 jumonji C domain containing histone demethylase 1
homolog D [Homo sapiens]
Length = 941
Score = 274 bits (701), Expect = 4e-73
Identities = 134/320 (41%), Positives = 198/320 (61%), Gaps = 17/320 (5%)
Query: 49 RYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPL 106
R+D E + D + V + ++LRS+++ + + M G Y+++ VP+
Sbjct: 102 RHDYTE-IDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPI 160
Query: 107 IFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQ 166
+ + D LG+++P P F+V DV+ VG +++DV+DV Q ++M++ +V+Y+ P
Sbjct: 161 MVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPN-- 218
Query: 167 RDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKV 226
R K+ NVISLEFS TK+ LV+ P + + WV+N WP + P V
Sbjct: 219 RPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDD------------SVFPKPFV 266
Query: 227 KKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDI 286
+KYCLM V+ +TDFHIDFGGTSVWYHV G KIF+LI PT NLA YE W S QS++
Sbjct: 267 QKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQSEV 326
Query: 287 FLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIED 346
F GD+V++C + +KQG+T F+P+GWIHAV T D + FGGN LH+ N+ MQLR YE+E
Sbjct: 327 FFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEK 386
Query: 347 RTRVQPKFRYPFYYEMCWYV 366
R + F++PF+ +CW+V
Sbjct: 387 RLKTPDLFKFPFFEAICWFV 406
Score = 32.3 bits (72), Expect = 3.1
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 6/54 (11%)
Query: 682 NLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCN--HAGKTGKQKR 733
N ++EC IC + H C+ ++E V D + CP C H K++R
Sbjct: 49 NRFMIECDICKDWFHGSCVGVEEHHAVDID----LYHCPNCAVLHGSSLMKKRR 98
>gi|117190342 PHD finger protein 2 [Homo sapiens]
Length = 1096
Score = 248 bits (632), Expect = 4e-65
Identities = 123/297 (41%), Positives = 175/297 (58%), Gaps = 16/297 (5%)
Query: 72 EKLRSQLYQG--DFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVK 129
++LRS+ + D V + G Y++ P++ +KDGLG+ +P P F V DV+
Sbjct: 91 KELRSRTFPSAEDVVARVPGSQLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVE 150
Query: 130 LLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKR 189
VG R VDV DV QK +M + +FV YY + R ++ NV +LEFS T++ V+
Sbjct: 151 NYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYS--TNRKRVLNVTNLEFSDTRMSSFVEP 208
Query: 190 PTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTS 249
P +V + WV+N WP A + PKV KYCL+ VK +TDFHID GG S
Sbjct: 209 PDIVKKLSWVENYWPDD------------ALLAKPKVTKYCLICVKDSYTDFHIDSGGAS 256
Query: 250 VWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIP 309
WYHV +G K F+LI P N++LYE W + S++F D+V++C + +KQG T FIP
Sbjct: 257 AWYHVLKGEKTFYLIRPASANISLYERWRSASNHSEMFFADQVDKCYKCIVKQGQTLFIP 316
Query: 310 SGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYV 366
SGWI+A TPVD L F G+ LHS +V MQ+R YE+E R ++ ++P + CWY+
Sbjct: 317 SGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYM 373
Score = 33.1 bits (74), Expect = 1.8
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 11/59 (18%)
Query: 685 LMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKC--NHAGKTGKQKR-----GPG 736
++EC C + H C+ ++E E D + CP C H T K+KR GPG
Sbjct: 20 MIECDACKDWFHGSCVGVEEEEAPDID----IYHCPNCEKTHGKSTLKKKRTWHKHGPG 74
Score = 33.1 bits (74), Expect = 1.8
Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 27/137 (19%)
Query: 930 KKKVKMRRKRRLPNKELSRELSKELNHEIQRTEN---SLANENQQPIKSEPESEGE-EPK 985
KK+ + LP +L K+L EI+ +EN ++ E S+ +G+ E +
Sbjct: 411 KKQALAEHEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSDEVCDGDREKE 470
Query: 986 RPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPS--VSPPKCIQMERHVI 1043
PP E P+ L ++ S + P+ + P PS PPK
Sbjct: 471 EPPSPIEAT---------PPQSLLEKV--SKKKTPKTVKMPKPSKIPKPPK--------- 510
Query: 1044 RPPPISPPPDSLPLDDG 1060
PP PP +L L DG
Sbjct: 511 -PPKPPRPPKTLKLKDG 526
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 77.8 bits (190), Expect = 6e-14
Identities = 75/269 (27%), Positives = 117/269 (43%), Gaps = 48/269 (17%)
Query: 1089 CRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPV--SLDLSWTN-ISKKQLSWLI 1145
C + +++C R +DL C SIT + L + P+ L++SW + ++K + L+
Sbjct: 135 CTSLSKFCSKLR---HLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALV 191
Query: 1146 NRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLL-------- 1195
GL+ L L GC+ + AL + CP L TL++Q + D + +
Sbjct: 192 RGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQS 251
Query: 1196 ------SPPTD---NRPGQMDNRSKL------------------RNIVELRLAGLD---- 1224
S TD N GQ R ++ RN EL L+
Sbjct: 252 LCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQ 311
Query: 1225 ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ 1284
ITD++L + H P L L LS+C +TD I L G D L I L +C +TD
Sbjct: 312 ITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHL-GNGACAHDQLEVIELDNCPLITDA 370
Query: 1285 CLSFFKRCGNICHIDLRYCKQVTKEGCEQ 1313
L K C ++ I+L C+Q+T+ G ++
Sbjct: 371 SLEHLKSCHSLERIELYDCQQITRAGIKR 399
Score = 65.9 bits (159), Expect = 3e-10
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 45/249 (18%)
Query: 1067 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRRQ 1125
+E+ + +FS+L LC C +V R WN D W RIDL + + I ++
Sbjct: 30 KELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVE------ 83
Query: 1126 PVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL--CSSSCPLLRTLDVQWV 1183
NISK+ + LR L L GC + +AL + +C + L++
Sbjct: 84 ---------NISKRCGGF-------LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGC 127
Query: 1184 EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG-LDITDASLRLIIRHMPLLSK 1242
DA L SKLR+ L LA IT+ SL+ + PLL +
Sbjct: 128 TKTTDATCTSL-----------SKFCSKLRH---LDLASCTSITNMSLKALSEGCPLLEQ 173
Query: 1243 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLR 1301
L++S+C+ VT I L L + L C ++ D+ L + C + ++L+
Sbjct: 174 LNISWCDQVTKDGIQAL----VRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQ 229
Query: 1302 YCKQVTKEG 1310
C Q+T EG
Sbjct: 230 TCLQITDEG 238
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/168 (24%), Positives = 79/168 (47%), Gaps = 10/168 (5%)
Query: 1152 RDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSK 1211
++L+L S++ V LC + + R +V ++G + Q DL D ++N SK
Sbjct: 30 KELLLRIFSFLDVVTLCRCA-QVSRAWNVLALDG-SNWQRIDLFDFQRDIEGRVVENISK 87
Query: 1212 LRN--IVELRLAG-LDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD 1268
+ +L L G L + D +LR ++ + L+L+ C TD + L+ + R
Sbjct: 88 RCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLR- 146
Query: 1269 SLTEINLSDCNKVTDQCLSFFKR-CGNICHIDLRYCKQVTKEGCEQFI 1315
++L+ C +T+ L C + +++ +C QVTK+G + +
Sbjct: 147 ---HLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALV 191
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 70.9 bits (172), Expect = 8e-12
Identities = 76/290 (26%), Positives = 119/290 (41%), Gaps = 52/290 (17%)
Query: 1077 LSHQDLCVCMRV----CRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIR--RQPVSLD 1130
+ H +L C ++ C + +R+C + +DL C SIT L GI R L+
Sbjct: 106 IEHLNLNGCTKITDSTCYSLSRFCSKLK---HLDLTSCVSITNSSLKGISEGCRNLEYLN 162
Query: 1131 LSWTN-ISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL-----------------CSS-- 1170
LSW + I+K + L+ GL+ L+L GC+ + AL CS
Sbjct: 163 LSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRIT 222
Query: 1171 ---------SCPLLRTLDVQWVEGLKDAQMRDL---------LSPPTDNRPGQMDNRSKL 1212
C L+ L + L DA + L L +
Sbjct: 223 DEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLA 282
Query: 1213 RNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRD 1268
RN EL L+ ITD++L + H P L L LS+C +TD I L + T +
Sbjct: 283 RNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI-LHLSNSTCGHE 341
Query: 1269 SLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1318
L + L +C +TD L + C + ++L C+QVT+ G ++ A++
Sbjct: 342 RLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQL 391
Score = 54.7 bits (130), Expect = 6e-07
Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 29/251 (11%)
Query: 1067 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 1124
+E+ + +FS+L LC C ++ + WN D W RIDL N + ++ I +R
Sbjct: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISKRC 76
Query: 1125 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS--CPLLRTL 1178
+ +SL + L + L L+GC+ I S S S C L+ L
Sbjct: 77 GGFLRKLSL-RGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHL 135
Query: 1179 DVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLIIRHM 1237
D+ + ++ ++ + RN+ L L+ D IT + ++R
Sbjct: 136 DLTSCVSITNSSLKGI--------------SEGCRNLEYLNLSWCDQITKDGIEALVRGC 181
Query: 1238 PLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ-CLSFFKRCGNIC 1296
L L L C + D+++ + L +NL C+++TD+ + + C +
Sbjct: 182 RGLKALLLRGCTQLEDEALKHI----QNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQ 237
Query: 1297 HIDLRYCKQVT 1307
+ L C +T
Sbjct: 238 ALCLSGCSNLT 248
>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
Length = 660
Score = 67.0 bits (162), Expect = 1e-10
Identities = 27/46 (58%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Query: 607 RRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 651
+R C +CEAC RTE CG C FC+DMKKFGGP +++Q C +RQC
Sbjct: 163 KRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
Length = 656
Score = 67.0 bits (162), Expect = 1e-10
Identities = 27/46 (58%), Positives = 34/46 (73%), Gaps = 1/46 (2%)
Query: 607 RRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 651
+R C +CEAC RTE CG C FC+DMKKFGGP +++Q C +RQC
Sbjct: 163 KRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 65.1 bits (157), Expect = 4e-10
Identities = 83/309 (26%), Positives = 119/309 (38%), Gaps = 49/309 (15%)
Query: 1022 VISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQD 1081
V S PP ++ P + R RP D LP H M + +FS+L
Sbjct: 88 VHSPPPTRLTHP----LIRLASRPQKEQASIDRLP-----DHSM-----VQIFSFLPTNQ 133
Query: 1082 LCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRR-----QPVSLDLSWTNI 1136
LC C RVCR W D RLW I L L + RR V L L +
Sbjct: 134 LCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTV 193
Query: 1137 S------KKQLSWLINRLPGLRDLVLSGCSWIAVSALCS--SSCPLLRTLDVQWVEGLKD 1188
S + L + P LR L +SGC I+ A+ S CP L LDV +
Sbjct: 194 SGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTC 253
Query: 1189 AQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDA------SLRLIIRHMPLLSK 1242
+ S G+ ++ + LD+TD L I H L+
Sbjct: 254 ISLTREASIKLSPLHGK-----------QISIRYLDMTDCFVLEDEGLHTIAAHCTQLTH 302
Query: 1243 LHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCL-SFFKRCGNICHIDLR 1301
L+L C +TD+ + L S+ E+++SDC V+D L K + ++ +
Sbjct: 303 LYLRRCVRLTDEGLRYLVIYCA----SIKELSVSDCRFVSDFGLREIAKLESRLRYLSIA 358
Query: 1302 YCKQVTKEG 1310
+C +VT G
Sbjct: 359 HCGRVTDVG 367
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 62.0 bits (149), Expect = 4e-09
Identities = 25/43 (58%), Positives = 30/43 (69%)
Query: 609 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 651
+R RC CE C + ECG+C CKDM KFGG GR KQ+C R+C
Sbjct: 665 KRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRC 707
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 62.0 bits (149), Expect = 4e-09
Identities = 25/43 (58%), Positives = 30/43 (69%)
Query: 609 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 651
+R RC CE C + ECG+C CKDM KFGG GR KQ+C R+C
Sbjct: 649 KRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRC 691
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 59.7 bits (143), Expect = 2e-08
Identities = 84/384 (21%), Positives = 142/384 (36%), Gaps = 98/384 (25%)
Query: 1019 PPRVISRPPPSVSPPKCIQMERHVIRPPPISP---PPDSLPLDDGAAH---VMHREVWMA 1072
PP + PPPS++ P + R + P +P P +L A ++
Sbjct: 49 PPPPPTLPPPSLAAP----LSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNG 104
Query: 1073 VFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRI--------------------------- 1105
+F Y S + CV +VC+ W R + W +
Sbjct: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFA 164
Query: 1106 -------------DLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLR 1152
DL+ C+ I LS ++ ++ L + I+ L ++ ++ G+
Sbjct: 165 ARGFEGFCLVGVSDLDICEFIDNYALS---KKGVKAMSLKRSTITDAGLEVMLEQMQGVV 221
Query: 1153 DLVLSGCS-------WIAVSA----LCSSSC---------------PLLRTLDVQWV--- 1183
L LSGC+ W ++SA L S C P L L +Q
Sbjct: 222 RLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVT 281
Query: 1184 ----------EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRL 1232
+G +R LLS G ++ L N+ L L+G +TD + L
Sbjct: 282 DTALAYFTARQGHSTHTLR-LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVEL 340
Query: 1233 IIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRC 1292
+ ++ L L LS+C +TD ++ + L E+ L C ++TD LS+
Sbjct: 341 VAENLRKLRSLDLSWCPRITDMALEYVAC----DLHRLEELVLDRCVRITDTGLSYLSTM 396
Query: 1293 GNICHIDLRYCKQVTKEGCEQFIA 1316
++ + LR+C QV G + +A
Sbjct: 397 SSLRSLYLRWCCQVQDFGLKHLLA 420
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 59.7 bits (143), Expect = 2e-08
Identities = 67/293 (22%), Positives = 108/293 (36%), Gaps = 39/293 (13%)
Query: 749 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSD------EHSKKVPPDGLLRRKSDDVHLRK 802
+E++ +R+ +E +RR +PRRRS + S P + +S K
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK 216
Query: 803 KRKYEKPQELSGRKRASSLQTSPGSSSHLS-PRP-PLGSSLSPWWRSSLTYFQQQLKPGK 860
K K + E S + + S+Q + +S L P+P P+ P P K
Sbjct: 217 KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP-------------SPEK 263
Query: 861 EDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPS 920
K ++K ++ + R ++ R P+ R SRS SP PS
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR-------PRRRHRSRSRSYSPRRRPS 316
Query: 921 TEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESE 980
P +++ RR P SR ++R S A+ + S
Sbjct: 317 PR--RRPSPRRRTPPRRMPPPPRHRRSRS-------PVRRRRRSSASLSGSSSSSSSSRS 367
Query: 981 GEEPKRPPGICERPHRFSKGL--NGTPRELRHQLGPSLRSPPRVISRPPPSVS 1031
PK+PP P R ++ L + +P RH+ P PP+ P P S
Sbjct: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
Score = 57.4 bits (137), Expect = 9e-08
Identities = 77/308 (25%), Positives = 116/308 (37%), Gaps = 62/308 (20%)
Query: 748 LKEQKMNRD--NKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKR- 804
+K+Q ++D +KE +E ++ + E +PRRR +RR+ H R R
Sbjct: 144 MKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRH 203
Query: 805 ------------KYEKPQEL---SGRKRASSLQTSPGSSSHLS-PRP-PLGSSLSPWWRS 847
K EK EL S + + S+Q + +S L P+P P+ P
Sbjct: 204 RTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP---- 259
Query: 848 SLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRES 907
P K K ++K ++ + R ++ R P+ R
Sbjct: 260 ---------SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR-------PRRRHR 303
Query: 908 DHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLAN 967
SRS SP PS P +++ RR P SR ++R S A+
Sbjct: 304 SRSRSYSPRRRPSPR--RRPSPRRRTPPRRMPPPPRHRRSRS-------PVRRRRRSSAS 354
Query: 968 ENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRP- 1026
+ S PK+PP K + PR+ R +L PS SPPR RP
Sbjct: 355 LSGSSSSSSSSRSRSPPKKPP----------KRTSSPPRKTR-RLSPS-ASPPRRRHRPS 402
Query: 1027 PPSVSPPK 1034
PP+ PPK
Sbjct: 403 PPATPPPK 410
Score = 46.2 bits (108), Expect = 2e-04
Identities = 65/295 (22%), Positives = 104/295 (35%), Gaps = 33/295 (11%)
Query: 757 NKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK 816
+ E + P + + E RRR S+ P R+K R++R P + R+
Sbjct: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPP--TRRR 558
Query: 817 RASSLQTSPGSSSHLSPRP------PLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRR 870
R+ S P +P P P SP R Q++ P K R+
Sbjct: 559 RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK--RRTAS 616
Query: 871 SWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTR-----ESDHSRSSSPTAGPSTEGAE 925
+ R + + P RR P + +P R S H + SSP+ ST A
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR--STREAR 674
Query: 926 GPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPK 985
P+ K+ + R P S ++R +S Q P S P
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPP-------PVRRGASSSPQRRQSP------SPSTRPI 721
Query: 986 RPPGICERPHRFSKGLNGTPRELRH-QLGPSLRSPPRVISRPPPSVSPPKCIQME 1039
R P + K + +P+ +R S+ P ++ PP +PP +Q +
Sbjct: 722 RRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP--APPSPVQSQ 774
Score = 43.1 bits (100), Expect = 0.002
Identities = 65/262 (24%), Positives = 94/262 (35%), Gaps = 54/262 (20%)
Query: 763 PAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQ-----ELSGRKR 817
P KRR P++RS +K+ P + + R R+ PQ S R R
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
Query: 818 ASSLQTSP-----GSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSW 872
A +SP G+SS R S P R S T +P K K +S
Sbjct: 690 APQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP-----EPKKIKKAASPSPQSV 744
Query: 873 KNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDH-----------SRSSSPTAGPST 921
+ +++ P EP + P APP +S ++ SPT PS
Sbjct: 745 RRVSSSRSVSGSP------EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
Query: 922 ------EGAEGPEEKKKVKMRRKRRLPNKELSRELSKEL---------NHEIQRTENSLA 966
EG ++KKK K +K + K + K + I +LA
Sbjct: 799 PRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLA 858
Query: 967 NENQQPI-----KSEPESEGEE 983
E +P+ K E ESE E+
Sbjct: 859 QE--EPVAAPEPKKETESEAED 878
Score = 41.6 bits (96), Expect = 0.005
Identities = 82/369 (22%), Positives = 126/369 (34%), Gaps = 75/369 (20%)
Query: 725 AGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPA-----KRRSECEEAPRRRSD 779
+GK K K + S P E + ++K G+ A +RR + + SD
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 780 EHSKKVPPDGLLRR---KSDDVHLRKKRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPP 836
S D +R K+ +V R++ + S RKR +TSP SP PP
Sbjct: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQK--ETSPRGRRRRSPSPP 553
Query: 837 LGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDE 896
T ++ P + RR R + P RR P
Sbjct: 554 P------------TRRRRSPSPAPPPR-----RRRTPTPPPRRRTPSPPPRRRSPSPRRY 596
Query: 897 LPE-------APPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRE 949
P +PP R R++SP P + P K++V P K+ S
Sbjct: 597 SPPIQRRYSPSPPPKR-----RTASPPPPPKRRASPSPPPKRRVS----HSPPPKQRSSP 647
Query: 950 LSKELNHEIQRTENSLANENQQPIKSEPESEGEEPK---------RPPGICERPHRFSKG 1000
++K + + +S + P +S E+ +P R P P +G
Sbjct: 648 VTKRRSPSL----SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703
Query: 1001 LNGTPRELRHQLGPSLRSPPRVISRPP----------PSVSPPKCIQMERHV-------I 1043
+ +P+ R PS R P R +SR P PS + + R V
Sbjct: 704 ASSSPQR-RQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761
Query: 1044 RPPPISPPP 1052
+ PP P P
Sbjct: 762 KKPPAPPSP 770
Score = 34.7 bits (78), Expect = 0.63
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 23/136 (16%)
Query: 408 LEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALR 467
++ ++E D++ +EE+E E R R+P+ S SP ++ +P R
Sbjct: 144 MKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP------------RRRSSPVRR 191
Query: 468 FLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESL 527
KR+ S KS ++P SPA E K L E +K + V++ S
Sbjct: 192 ERKRSHSRSPRHRTKS--------RSP--SPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 528 PENKKC-VPEGIEDPQ 542
+ K PE I +P+
Sbjct: 242 SDILKVPKPEPIPEPK 257
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 58.2 bits (139), Expect = 5e-08
Identities = 67/287 (23%), Positives = 123/287 (42%), Gaps = 55/287 (19%)
Query: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1122
E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I
Sbjct: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
Query: 1123 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1174
QP++ S + LS + + L ++ S C
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
Query: 1175 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1233
L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ +
Sbjct: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
Query: 1234 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1291
+ L +L+LS+C T++ + + A +++T++NLS K + +R
Sbjct: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
Query: 1292 CGNICHIDLRYCKQVTKEGCEQF-----IAEMSVSVQFGQVEEKLLQ 1333
C N+ H+DL + + ++F + +S+S + + E LL+
Sbjct: 309 CPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLE 355
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 [Homo
sapiens]
Length = 690
Score = 57.8 bits (138), Expect = 7e-08
Identities = 62/248 (25%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 1071 MAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLD 1130
+ +F YLS +D+ +C +V W LW ID + K++ P + VS
Sbjct: 164 LQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIP-------DKYIVSTL 216
Query: 1131 LSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQ 1190
W RL LR L GC + S C L+ L+V D
Sbjct: 217 QRW-------------RLNVLR-LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDES 262
Query: 1191 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1250
MR + ++ PG ++ L L+ IT+ ++RL+ RH L L L+YC
Sbjct: 263 MRHI----SEGCPG----------VLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 1251 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKE 1309
TD+ + L +G L ++LS C +++ Q + C I H+ + +T +
Sbjct: 309 FTDKGLQYLN-LGNGCH-KLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT-D 365
Query: 1310 GCEQFIAE 1317
C + + E
Sbjct: 366 NCVKALVE 373
Score = 50.4 bits (119), Expect = 1e-05
Identities = 46/194 (23%), Positives = 87/194 (44%), Gaps = 37/194 (19%)
Query: 1154 LVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPT-------DNRPG 1204
L LSGC+ I+V ++SC + L + + L D ++ L+ + P
Sbjct: 329 LDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPH 388
Query: 1205 QMDNRSKLRNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1260
D + + +LR + +TDAS + I ++ P LS ++++ C +TD S+ L+
Sbjct: 389 ISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 1261 AVGTTTRDSLT-----------------------EINLSDCNKVTD-QCLSFFKRCGNIC 1296
+ T +L E+NLS+C +++D + +RC N+
Sbjct: 449 PLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 1297 HIDLRYCKQVTKEG 1310
++ LR C+ +T +G
Sbjct: 509 YLSLRNCEHLTAQG 522
Score = 41.2 bits (95), Expect = 0.007
Identities = 42/179 (23%), Positives = 79/179 (44%), Gaps = 20/179 (11%)
Query: 1136 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL--LRTLDVQWVEGLKDAQMRD 1193
++ ++ P L + ++ C I S+L S S PL L L++ + D ++
Sbjct: 413 VTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS-PLKQLTVLNLANCVRIGDMGLKQ 471
Query: 1194 LLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTD 1253
L P R +++ L N V L +DAS+ + P L+ L L C H+T
Sbjct: 472 FLDGPASMRIRELN----LSNCVRL-------SDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 1254 QSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCE 1312
Q I + + SL I+LS + ++++ L+ R + + + C ++T +G +
Sbjct: 521 QGIGYIVNI-----FSLVSIDLSGTD-ISNEGLNVLSRHKKLKELSVSECYRITDDGIQ 573
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 [Homo
sapiens]
Length = 735
Score = 57.8 bits (138), Expect = 7e-08
Identities = 62/248 (25%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 1071 MAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLD 1130
+ +F YLS +D+ +C +V W LW ID + K++ P + VS
Sbjct: 164 LQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIP-------DKYIVSTL 216
Query: 1131 LSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQ 1190
W RL LR L GC + S C L+ L+V D
Sbjct: 217 QRW-------------RLNVLR-LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDES 262
Query: 1191 MRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNH 1250
MR + ++ PG ++ L L+ IT+ ++RL+ RH L L L+YC
Sbjct: 263 MRHI----SEGCPG----------VLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRR 308
Query: 1251 VTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKE 1309
TD+ + L +G L ++LS C +++ Q + C I H+ + +T +
Sbjct: 309 FTDKGLQYLN-LGNGCH-KLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLT-D 365
Query: 1310 GCEQFIAE 1317
C + + E
Sbjct: 366 NCVKALVE 373
Score = 50.4 bits (119), Expect = 1e-05
Identities = 46/194 (23%), Positives = 87/194 (44%), Gaps = 37/194 (19%)
Query: 1154 LVLSGCSWIAVSAL--CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPT-------DNRPG 1204
L LSGC+ I+V ++SC + L + + L D ++ L+ + P
Sbjct: 329 LDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPH 388
Query: 1205 QMDNRSKLRNIVELRLAGLD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLT 1260
D + + +LR + +TDAS + I ++ P LS ++++ C +TD S+ L+
Sbjct: 389 ISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 1261 AVGTTTRDSLT-----------------------EINLSDCNKVTD-QCLSFFKRCGNIC 1296
+ T +L E+NLS+C +++D + +RC N+
Sbjct: 449 PLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 1297 HIDLRYCKQVTKEG 1310
++ LR C+ +T +G
Sbjct: 509 YLSLRNCEHLTAQG 522
Score = 48.1 bits (113), Expect = 6e-05
Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 34/194 (17%)
Query: 1136 ISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL--LRTLDVQWVEGLKDAQMRD 1193
++ ++ P L + ++ C I S+L S S PL L L++ + D ++
Sbjct: 413 VTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS-PLKQLTVLNLANCVRIGDMGLKQ 471
Query: 1194 LLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTD 1253
L P R +++ L N V L +DAS+ + P L+ L L C H+T
Sbjct: 472 FLDGPASMRIRELN----LSNCVRL-------SDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 1254 QSINLLTAV---------GT----------TTRDSLTEINLSDCNKVTDQCLSFFKRCGN 1294
Q I + + GT + L E+++S+C ++TD + F +
Sbjct: 521 QGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSL 580
Query: 1295 IC-HIDLRYCKQVT 1307
I H+D+ YC Q++
Sbjct: 581 ILEHLDVSYCSQLS 594
Score = 40.8 bits (94), Expect = 0.009
Identities = 46/207 (22%), Positives = 93/207 (44%), Gaps = 28/207 (13%)
Query: 1151 LRDLVLSGCSWIAVSALC--SSSCPLLRTLDVQWVEGLKDAQMRDLLS---------PPT 1199
+R+L LS C ++ +++ S CP L L ++ E L + +++ T
Sbjct: 481 IRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGT 540
Query: 1200 DNRPGQMDNRSKLRNIVELRLAGL-DITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINL 1258
D ++ S+ + + EL ++ ITD ++ + +L L +SYC+ ++D I
Sbjct: 541 DISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKA 600
Query: 1259 LTAVGTTTRDSLTEINLSDCNKVTDQCLSFFK-RCGNICHIDLRYCKQVTKE-------G 1310
L +LT ++++ C K+TD + +C + +D+ C +T + G
Sbjct: 601 LAIYCI----NLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIG 656
Query: 1311 CEQF-IAEMSVSVQFGQVEEKLLQKLS 1336
C+Q I +M + +K Q++S
Sbjct: 657 CKQLRILKMQYCT---NISKKAAQRMS 680
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 57.4 bits (137), Expect = 9e-08
Identities = 67/286 (23%), Positives = 122/286 (42%), Gaps = 55/286 (19%)
Query: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1122
E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I
Sbjct: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
Query: 1123 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1174
QP++ S + LS + + L ++ S C
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
Query: 1175 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1233
L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ +
Sbjct: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
Query: 1234 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1291
+ L +L+LS+C T++ + + A +++T++NLS K + +R
Sbjct: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
Query: 1292 CGNICHIDLRYCKQVTKEGCEQF-----IAEMSVSVQFGQVEEKLL 1332
C N+ H+DL + + ++F + +S+S + + E LL
Sbjct: 309 CPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 55.1 bits (131), Expect = 5e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 309 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 355
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 55.1 bits (131), Expect = 5e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 283 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 329
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 55.1 bits (131), Expect = 5e-07
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 607 RRRRTRCRKCEACLRT-ECGECHFCKDMKKFGGPGRMKQSCIMRQCI 652
RR+ +C C ACLR +CG C FC D KFGG + +Q C RQC+
Sbjct: 332 RRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCL 378
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 54.7 bits (130), Expect = 6e-07
Identities = 64/279 (22%), Positives = 108/279 (38%), Gaps = 55/279 (19%)
Query: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLN-HCKSITP-----LMLSGI 1121
E+ +F YL +D +VC W K +W ++ H + P L GI
Sbjct: 11 ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70
Query: 1122 IRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQ 1181
R Q +SL ++ LS++I + + L LSGC + + L + VQ
Sbjct: 71 RRVQILSL--------RRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAF--------VQ 114
Query: 1182 WVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGL-DITDASLRLIIRHMPLL 1240
+ L+ + L TD+ G++ L+ + L L G +IT+ L LI + L
Sbjct: 115 EIGSLRALNL-SLCKQITDSSLGRI--AQYLKGLEVLELGGCSNITNTGLLLIAWGLQRL 171
Query: 1241 SKLHLSYCNHVTDQSINLLTAVGTTTRDS-----------------------------LT 1271
L+L C H++D I L + + + L
Sbjct: 172 KSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLR 231
Query: 1272 EINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEG 1310
+NLS C ++D L G++ ++LR C ++ G
Sbjct: 232 LLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTG 270
Score = 52.0 bits (123), Expect = 4e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 37/219 (16%)
Query: 1105 IDLNHCKSITPLMLSGIIRRQPVSLD--LSWTNISKKQLSWLINRLPGLRDLVLSGCSWI 1162
+ + H +T G + + ++L T++S K +S L GLR L LS C I
Sbjct: 185 VGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHIS---RGLTGLRLLNLSFCGGI 241
Query: 1163 AVSALCS-SSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLA 1221
+ + L S LR+L+++ + + D + L + LRL+
Sbjct: 242 SDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLA-------------------MGSLRLS 282
Query: 1222 GLDIT------DASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINL 1275
GLD++ D SL I + + L L L C H++D IN + L +N+
Sbjct: 283 GLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSC-HISDDGINRMVR----QMHGLRTLNI 337
Query: 1276 SDCNKVTDQCLSFF-KRCGNICHIDLRYCKQVTKEGCEQ 1313
C ++TD+ L + + IDL C ++TK G E+
Sbjct: 338 GQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLER 376
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 54.7 bits (130), Expect = 6e-07
Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 605 GARRRRTRCRKCEACLRTE-CGECHFCKDMKKFGGPGRMKQSCIMRQC 651
G + R RC C CLR + CG C C D KFGGP KQ C+ R+C
Sbjct: 958 GKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKC 1005
Score = 36.6 bits (83), Expect = 0.17
Identities = 27/115 (23%), Positives = 43/115 (37%), Gaps = 8/115 (6%)
Query: 936 RRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPH 995
+++++L ++E ++ +E + E + E E P + E++ P P P
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 996 RFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISP 1050
P P L PP PPP SPP E PPP+ P
Sbjct: 416 PLPPPSTSPP--------PPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Score = 32.3 bits (72), Expect = 3.1
Identities = 80/388 (20%), Positives = 126/388 (32%), Gaps = 96/388 (24%)
Query: 723 NHAGKTGKQK-RGPGFKYASNLPGSLLKEQKMNRDN---KEGQEPAKRRSECEEAPRRRS 778
+ G+ G+ + RG G + S K+ KM + + + GQ + ++ P+RR
Sbjct: 286 SRGGRGGRGRGRGGGLPFVIKFV-SRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRV 344
Query: 779 DEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRK-RASSLQTSPGSSSHLS--PRP 835
P +K DD KK + EK +E ++ RA + + P + + P P
Sbjct: 345 GSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP 404
Query: 836 PL---GSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQE 892
PL S P T L P + L + P ++E
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV------------SPPPLPSPPPPPAQEE 452
Query: 893 PEDELPEAPPKTRESDHSR--------------------SSSPTAGPSTEGAEGPEEKKK 932
E+ P P T R +S PT PST PE+
Sbjct: 453 QEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPT 512
Query: 933 VKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICE 992
V + L N Q ++ + + IK+ E+P +PP +
Sbjct: 513 VAPKSTTFLKNIR-------------QFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV-- 557
Query: 993 RPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKC----------IQMERHV 1042
E+ L P + + P V P P SPP+ + R +
Sbjct: 558 --------------EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI 603
Query: 1043 IR--------------PPPISPPPDSLP 1056
+R PPP +PPP P
Sbjct: 604 LREPTFRWTSLTRELPPPPPAPPPPPAP 631
Score = 32.3 bits (72), Expect = 3.1
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 12/70 (17%)
Query: 661 VCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECP 720
VCL+C G + L+ C +C + HP CL+ E + + C C
Sbjct: 1203 VCLLCASKGLHE------------LVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCK 1250
Query: 721 KCNHAGKTGK 730
C+ G+ G+
Sbjct: 1251 FCHVCGRKGR 1260
Score = 32.0 bits (71), Expect = 4.1
Identities = 35/150 (23%), Positives = 49/150 (32%), Gaps = 8/150 (5%)
Query: 884 KPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPN 943
K RRF DE P PPK S R T+ P + + +P
Sbjct: 541 KTPRRFM----DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL 596
Query: 944 KELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNG 1003
E R + +E SL E P + P P P R +
Sbjct: 597 PEKRRSILREPTFRW----TSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQF 652
Query: 1004 TPRELRHQLGPSLRSPPRVISRPPPSVSPP 1033
TP E ++ S+ +PP + + P PP
Sbjct: 653 TPSEAHLKIYESVLTPPPLGAPEAPEPEPP 682
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 50.1 bits (118), Expect = 1e-05
Identities = 118/618 (19%), Positives = 230/618 (37%), Gaps = 60/618 (9%)
Query: 378 SHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPK 437
+H+ + + + +++ K ++ ++ EE +++ E+E K+EEG+ + +
Sbjct: 434 THIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEE--EKEAKEEEGKEEEGGEE 491
Query: 438 PPTDGSTSPT-STPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTG 496
+G T S P+E+ + K+ K+P K +S E ++ + A
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 497 SPATEVS-----AKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNV 551
SPA E + AK E + EK +S + + P + P E K+
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP----EKAKSP 607
Query: 552 LKEHADDDPSLAITGVPVVTWPKKTPKNRA-VGRPKGKLGPASAVKLAANRTTAGARRRR 610
+KE A P+ A + V K+ K+ A V P+ P + + + +
Sbjct: 608 VKEEA-KSPAEAKSPV------KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA 660
Query: 611 TRCRKCEACLRTECGECHFCKDMKKFGGPGRMK-QSCIMRQCIAPVLPHTAVCLVCGEAG 669
K ++ ++ E K K K +S + + +P + V
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV-------- 712
Query: 670 KEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTG 729
KE+ E+ K + + E + P + K E + E +
Sbjct: 713 KEEAKSPEKAK-SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 730 KQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDG 789
++ R P K+ + +E K P K +S +E + E KK
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVK---------SPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 790 LLRRKSDDVHLRKKRKYEKPQE-------LSGRKRASSLQTSPGSSSHLSPRPPLGSSLS 842
++ + ++ K +K +E + K+ S + +P +P+P +
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE---APKPKVEEKKE 879
Query: 843 PWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALAN--KPLRR---FKQEPEDEL 897
P + K EDK +K K A ++ + KP + K+EP+D
Sbjct: 880 PAVEKPKESKVEAKKEEAEDK--KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 898 PEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHE 957
+ P K E ++ E A+ PEEK K + + K +K LS+E SK +
Sbjct: 938 AKEPSKPAEK--KEAAPEKKDTKEEKAKKPEEKPKTEAKAKE--DDKTLSKEPSKPKAEK 993
Query: 958 IQRTENSLANENQQPIKS 975
+++ ++ +++ P K+
Sbjct: 994 AEKSSSTDQKDSKPPEKA 1011
Score = 45.1 bits (105), Expect = 5e-04
Identities = 58/348 (16%), Positives = 127/348 (36%), Gaps = 36/348 (10%)
Query: 727 KTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVP 786
K+ ++ + P + A + P + E++ + E + P K +S +E + ++ S +
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 787 PDGLLRRKSDDVHLRK--KRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPW 844
+ + K + + P E+ ++A S S + P + SP
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE 664
Query: 845 WRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMA-------LANKPLRRFKQEPEDEL 897
S + + P K + + +S + A+ + A P++ + PE
Sbjct: 665 KAKSPVKAEAK-SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 898 PEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKK---------KVKMRRKRRLPNKELSR 948
+ + + ++S S E A+ PE+ K K + + R P +
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 949 ELSKELNHEIQRTENSLA----------------NENQQPIKSEPESEGEEPKRPPGICE 992
+ + E++ E + + E + P+K E + + + K PP E
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843
Query: 993 RPHRFSKGLNGTPRELRHQLGPSLRSP-PRVISRPPPSVSPPKCIQME 1039
+ ++ + + P +P P+V + P+V PK ++E
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Score = 43.9 bits (102), Expect = 0.001
Identities = 115/589 (19%), Positives = 212/589 (35%), Gaps = 83/589 (14%)
Query: 409 EMEEEACDQQPQEEE--EKDEEGEGRDRAPKPPTDGSTSP---TSTPSEDQEALGKKPKA 463
E E+EA +++ +EEE E++E G + PP + + SP +P +++ + K+
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKS 532
Query: 464 PALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEK 523
P K +S E KS A + K+P P + K + E+K EK
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSP--AKEEAKSP---PEAKSPEKEEAKSPAEVKS----PEK 583
Query: 524 LESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRA-V 582
+S + + P + P E K+ +KE A P+ A + V K+ K+ A V
Sbjct: 584 AKSPAKEEAKSPAEAKSP----EKAKSPVKEEAKS-PAEAKSPV------KEEAKSPAEV 632
Query: 583 GRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRM 642
P+ P + + + + K ++ ++ E K K
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692
Query: 643 K-QSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLK 701
K +S + + +P + V KE+ E+ K + + E + P +
Sbjct: 693 KAKSPVKEEAKSPEKAKSPV--------KEEAKSPEKAK-SPVKEEAKTPEKAKSPVKEE 743
Query: 702 IKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQ 761
K E + E + ++ R P K+ + +E K
Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK--------- 794
Query: 762 EPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSG------- 814
P K +S +E + E KK ++ + ++ K +K +E
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 815 RKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKN 874
K+ S + +P + P+P + P ++ KE K+ KK +
Sbjct: 855 EKKDSKKEEAPKKEA---PKPKVEEKKEP-----------AVEKPKESKVEAKK----EE 896
Query: 875 AEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVK 934
AED+ K+ P E EAP K + ++ T E + ++
Sbjct: 897 AEDK-----------KKVPTPE-KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Query: 935 MRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEE 983
+K P K+ ++E + E +TE + A E+ + + EP E
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTE-AKAKEDDKTLSKEPSKPKAE 992
Score = 43.1 bits (100), Expect = 0.002
Identities = 62/293 (21%), Positives = 107/293 (36%), Gaps = 21/293 (7%)
Query: 758 KEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKR 817
+E + P K +S +E +S E +K L KS + K + P + K
Sbjct: 728 EEAKTPEKAKSPVKE--EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 818 ASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFR--KKRRSWKNA 875
S ++ S + P + +P + ++ P KE++ + K + K A
Sbjct: 786 KSPVKEEV-KSPEKAKSPLKEDAKAP--EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 876 EDRMALANKPLRRFKQEPEDELP--EAP-PKTRESDHSRSSSPTAGPSTEGAEGPEEKKK 932
E+ A A K ++E P EAP PK E P E E+KKK
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 933 VKMRRKRRLPNKELSRELSKELNHEIQRTE--NSLANENQQPI---------KSEPESEG 981
V K E+ + + E+ + E ++ A E +P K E +
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962
Query: 982 EEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPK 1034
++P+ P + K L+ P + + + S + S+PP + K
Sbjct: 963 KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 35.4 bits (80), Expect = 0.37
Identities = 35/147 (23%), Positives = 61/147 (41%), Gaps = 7/147 (4%)
Query: 890 KQEPEDEL--PEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELS 947
K P +E PE K+ + ++S + P E A+ P E VK K + P KE +
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE---VKSPEKAKSPAKEEA 558
Query: 948 RELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRE 1007
+ + + E + ++ ++ + KS + E + P E+ K +P E
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS-PEKAKSPVKEEAKSPAE 617
Query: 1008 LRHQLGPSLRSPPRVISRPPPSVSPPK 1034
+ + +SP V S P + SP K
Sbjct: 618 AKSPVKEEAKSPAEVKS-PEKAKSPTK 643
Score = 34.7 bits (78), Expect = 0.63
Identities = 42/232 (18%), Positives = 90/232 (38%), Gaps = 15/232 (6%)
Query: 807 EKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFR 866
++ +E G++ + + PP + SP ++ P KE+
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPE--------KEAKSPVKEEAKSP 527
Query: 867 KKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEG 926
+ +S + E + K + K P E ++PP+ + + + SP S E A+
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKS-PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586
Query: 927 P--EEKK---KVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEG 981
P EE K + K K + P KE ++ ++ + + ++ ++ + KS + E
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 982 EEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPP 1033
+ P++ E+ S +P + + +SP + ++ P P
Sbjct: 647 KSPEKAKS-PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 49.3 bits (116), Expect = 2e-05
Identities = 39/180 (21%), Positives = 69/180 (38%), Gaps = 25/180 (13%)
Query: 886 LRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTE---GAEGPEEKKKVKMRRKRRLP 942
L + EP ++ EAPP + R + P AE P EK K K ++ ++
Sbjct: 42 LSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDK 101
Query: 943 NKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLN 1002
++ +E + ++ + ++P + P++ + ++PP ++P
Sbjct: 102 GPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKE------ 155
Query: 1003 GTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMER-HVIRPPPISPPPDSLPLDDGA 1061
PP+ +PP PP E PPP SP P+ LP + GA
Sbjct: 156 ---------------KPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGA 200
Score = 39.7 bits (91), Expect = 0.020
Identities = 79/345 (22%), Positives = 116/345 (33%), Gaps = 74/345 (21%)
Query: 721 KCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQE-PAKRRSECEEAPRRRSD 779
K GK GK+ +GP S L GS R K+G+E P K + +E P + +
Sbjct: 89 KTKDKGKKGKKDKGPKVPKES-LEGS-------PRPPKKGKEKPPKATKKPKEKPPKATK 140
Query: 780 EHSKKVPPDGLLRRKSDDVHLRKKRKYEK----------------------PQEL--SGR 815
+ +K PP + K KK K P+EL G
Sbjct: 141 KPKEK-PPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGG 199
Query: 816 KRASSLQTSPGSSSHLSPR------------PPL--GSSLSPWWRSSLTYFQQQLKPGKE 861
S+ +PG +H+ R P L + Y ++Q +P
Sbjct: 200 APLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPP 259
Query: 862 DKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAP---------PKTRESDHSRS 912
R+ R W + A A P R + + LP P P + D+
Sbjct: 260 PSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFG 319
Query: 913 SSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQP 972
P P E + EEK+++K +K KE E + ++++P
Sbjct: 320 PPPPQKPDAE-RQTDEEKEELKKPKKEDSSPKE-----------ETDKWAVEKGKDHKEP 367
Query: 973 IKSEPESE----GEEPKRPPGICERPHRFSKGLNGTPRELRHQLG 1013
K E E E+ K PP I HR LRH LG
Sbjct: 368 RKGEELEEEWTPTEKVKCPP-IGMESHRIEDNQIRASSMLRHGLG 411
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/288 (20%), Positives = 118/288 (40%), Gaps = 26/288 (9%)
Query: 749 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 808
+E++ R+N++ + +R + E R+R E ++ D +R+ ++ + ++ EK
Sbjct: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463
Query: 809 PQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKK 868
++ R R + G SP+PP + P ++ T Q+K E ++
Sbjct: 464 DRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATT--GPQVKRADE---WKDP 518
Query: 869 RRSWKNAEDRMALANKPLR-RFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGP 927
R K+ + ++ ++ P R R +++ A +R S SRSSS + S+
Sbjct: 519 WRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSS--SRSSSYSGSGSSRSRSRS 576
Query: 928 EEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSE------PESEG 981
R R + S S+ + + + + ++ I+++ P G
Sbjct: 577 SSYSSYSSRSSR---HSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAG 633
Query: 982 EEPKRPPGICERPHRFSKGL--------NGTPRELRHQLGPSLRSPPR 1021
E+ + P P + +K G PRE R + P+ R+PPR
Sbjct: 634 EKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPA-RTPPR 680
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 24/182 (13%)
Query: 387 ESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDG---- 442
+ +L D+ +DG + +EE+ + P +EEE D + DRA +P +
Sbjct: 26 DDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEE-DNHSDEEDRASEPKSQDQDSE 84
Query: 443 ----STSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSP 498
S PTS+P E++ G++ + LR +++ E +E +DY + P
Sbjct: 85 VNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEH------ELDYDEEVPEEP 138
Query: 499 ATEVSAKWTHLTEFELKGLKALVEKLESLP-ENKKCVPEGIEDPQALLEGVKNVLKEHAD 557
A V E E G + EK E P E K + + + ++ LE K KE D
Sbjct: 139 APAVQE-----DEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKES-LEAAKEKKKE--D 190
Query: 558 DD 559
DD
Sbjct: 191 DD 192
Score = 37.0 bits (84), Expect = 0.13
Identities = 50/216 (23%), Positives = 81/216 (37%), Gaps = 28/216 (12%)
Query: 860 KEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDH-SRSSSPTAG 918
+ DK ++++ W+ + ++ R +E E E + PK R SR + P
Sbjct: 441 ERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP--- 497
Query: 919 PSTEGAE-GPEEKKKVKMR---RKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIK 974
P E A GP+ K+ + + R+ + P K+L +S ++T S A+ +
Sbjct: 498 PKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASN---- 553
Query: 975 SEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPP------- 1027
S S G R S + + R RH RS R S P
Sbjct: 554 SSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPS 613
Query: 1028 ---PSV------SPPKCIQMERHVIRPPPISPPPDS 1054
PS+ +PP E+ V +P P PP +
Sbjct: 614 PHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA 649
Score = 30.8 bits (68), Expect = 9.1
Identities = 36/138 (26%), Positives = 51/138 (36%), Gaps = 27/138 (19%)
Query: 876 EDRMALANKPLRRFKQEPEDELPEA-PPKTRESD---HSRSSSPTAGPSTEGAEGPEEKK 931
ED + A P + + DE A PK+++ D + S PT+ P E + EE +
Sbjct: 49 EDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDR 108
Query: 932 KVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESE--GEEPKRPPG 989
+R + +EL HE+ E E P E E+E G E G
Sbjct: 109 TSDLRDEASSVTRELD-------EHELDYDEE--VPEEPAPAVQEDEAEKAGAEDDEEKG 159
Query: 990 ICERPHRFSKGLNGTPRE 1007
GTPRE
Sbjct: 160 ------------EGTPRE 165
Score = 30.8 bits (68), Expect = 9.1
Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 7/124 (5%)
Query: 403 SSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPK 462
++D E D+ Q DR + G + P + K P
Sbjct: 824 AADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPA 883
Query: 463 APALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFE--LKGLKAL 520
APA R KR LS +S+ S K T++ K A+ S K + L+ E LK LKA+
Sbjct: 884 APADR--KRQLSPQSKSSSKVTSVP---GKASDPGAASTKSGKASTLSRREELLKQLKAV 938
Query: 521 VEKL 524
+ +
Sbjct: 939 EDAI 942
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 48.1 bits (113), Expect = 6e-05
Identities = 44/169 (26%), Positives = 68/169 (40%), Gaps = 25/169 (14%)
Query: 898 PEAPPKT-----RESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSK 952
PEAPP +E + + P A+ PE KK + K +P E +
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801
Query: 953 ELNHEIQRT--ENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRH 1010
E+ E + E +A E ++P+ E E E P PP + E P + +
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP--PPAVPEEPKKI----------IPE 10849
Query: 1011 QLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDD 1059
+ P ++ P + PP P K I+ + RPPP PP + P +D
Sbjct: 10850 KKVPVIKKPE---APPPKEPEPEKVIEKPKLKPRPPP---PPPAPPKED 10892
Score = 39.7 bits (91), Expect = 0.020
Identities = 43/172 (25%), Positives = 70/172 (40%), Gaps = 22/172 (12%)
Query: 893 PEDE-LPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELS 951
PE+E LPE PK P P E + EKK V +++ P K E+
Sbjct: 10169 PEEEVLPEVKPKV----------PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKV--PEVP 10216
Query: 952 KELNHE---IQRTENSLANENQQPIKSEPESEGEEPKRPPGICE----RPHRFSKGLNGT 1004
K++ + + + E L E + + EP SE E P+ PP I E P R + +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276
Query: 1005 PRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLP 1056
E + + +PP +S+ P P + +++ P + P +P
Sbjct: 10277 VPEAPTPVPKKVEAPPAKVSKKIPEEKVP--VPVQKKEAPPAKVPEVPKKVP 10326
Score = 37.7 bits (86), Expect = 0.074
Identities = 66/330 (20%), Positives = 121/330 (36%), Gaps = 60/330 (18%)
Query: 743 LPGSLLKEQKMNRDNKEGQEPAK-----RRSECEEAPRRRSDEHSKKVPPDGLLRRKSDD 797
+P ++ E+K+ K PAK ++ EE P E ++ PP+
Sbjct: 10752 VPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPE--------- 10802
Query: 798 VHLRKKRKYEKPQELSGRKRASSLQTSPGS-SSHLSPR-PPLGSSLSPWWRSSLTYFQQQ 855
YE+P+E++ + + + P + P PP P ++
Sbjct: 10803 -------VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP----------KK 10845
Query: 856 LKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSP 915
+ P K+ + +K + + KP + + P P APPK E +
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP---PPAPPK--EDVKEKIFQL 10900
Query: 916 TAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKS 975
A P + E P+ +KV++ + ++ R+L E E + + ++P +
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 10960
Query: 976 EPESEGE--EPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPP------ 1027
EP+ E + E + P + E P P+ + P++ R I P
Sbjct: 10961 EPKVEPKKLEKVKKPAVPEPP---------PPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011
Query: 1028 -----PSVSPPKCIQMERHVIRPPPISPPP 1052
P+ P + E I+PPP+ P P
Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPPPVEPEP 11041
Score = 36.2 bits (82), Expect = 0.22
Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 16/212 (7%)
Query: 860 KEDKLFRKKRRSWKNAE--DRMALANKPLRRF--KQEPEDELPEAPPKTRESDHSRSSSP 915
+E ++F K + K E +++ KP + ++EP ++PE P K + R
Sbjct: 10428 EEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE 10487
Query: 916 TAGPSTEGAEG-------PEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANE 968
P T+ E PE+K V +K P ++ E KE+ E +
Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP-EAPKEVVPEKKVPVPPPKKP 10546
Query: 969 NQQPIK--SEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRP 1026
P K P++ E K P I +P + P+E+ + P + P
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 1027 PPSVSPPKCIQMERHVIRPPPISP--PPDSLP 1056
PK + E+ V PPP P PP +P
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP 10638
Score = 34.3 bits (77), Expect = 0.82
Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 21/175 (12%)
Query: 383 EYQRESMLIDAPRKPSIDGFSS---DSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPP 439
E ++ +L + P P + S + + E EE A +++ EEEK + PP
Sbjct: 10777 EVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP 10836
Query: 440 TDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPA 499
P E + + KKP+AP + E E+ ++ L P P P
Sbjct: 10837 PAVPEEPKKIIPEKKVPVIKKPEAPPPK------EPEPEKVIEKPKLKPRPPPPPPAPPK 10890
Query: 500 TEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIE-DPQALLEGVKNVLK 553
+V K + LKA+ +K +PE K VPE +E P + G K V K
Sbjct: 10891 EDVKEK--------IFQLKAIPKK--KVPE-KPQVPEKVELTPLKVPGGEKKVRK 10934
Score = 33.9 bits (76), Expect = 1.1
Identities = 29/122 (23%), Positives = 47/122 (38%), Gaps = 2/122 (1%)
Query: 374 VTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEE-EACDQQPQEEEEKDEEGEGR 432
VT + Y E + R+ + + + E EE E ++ Q EE ++ E E
Sbjct: 9720 VTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERY 9779
Query: 433 DRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPK 492
+ + T+ P +E + KPKAP + LK+ + E L PK
Sbjct: 9780 EEHEEYITEPE-KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPK 9838
Query: 493 TP 494
P
Sbjct: 9839 VP 9840
Score = 33.9 bits (76), Expect = 1.1
Identities = 40/166 (24%), Positives = 61/166 (36%), Gaps = 9/166 (5%)
Query: 893 PEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSK 952
PE ++P PPK E PT P PE+K + K P E+ E +
Sbjct: 10618 PEKKVPVPPPKKPEVP------PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE-PE 10670
Query: 953 ELNHEIQRTENSLANENQQP--IKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRH 1010
E+ E E E P + P+ E K P + ++P + P+E+
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP 10730
Query: 1011 QLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLP 1056
+ L P + + P PK + E+ V P PP +P
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVP 10776
Score = 33.5 bits (75), Expect = 1.4
Identities = 40/188 (21%), Positives = 69/188 (36%), Gaps = 42/188 (22%)
Query: 885 PLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNK 944
P+ + K+ P ++PE P K PEEK V + +K + P
Sbjct: 9966 PVPKKKEAPPAKVPEVPKK-----------------------PEEKVPVLIPKKEKPPPA 10002
Query: 945 ELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGT 1004
++ K + E + + +++ P E PK+P + P K +
Sbjct: 10003 KVPEVPKKPV------PEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAP 10056
Query: 1005 PR---ELRHQLGPSLRSP---PRVISRPPPSVSP-------PKCIQMERHVIRPPPISPP 1051
P E+ +L P + P P+ + PPP V P + E V+ I P
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116
Query: 1052 PDSLPLDD 1059
+ LP ++
Sbjct: 10117 EEVLPEEE 10124
Score = 32.3 bits (72), Expect = 3.1
Identities = 48/194 (24%), Positives = 75/194 (38%), Gaps = 22/194 (11%)
Query: 876 EDRMALANKPLRRFKQEPED--ELPEAPPKTRESDHSRSSSPTAGPSTE-------GAEG 926
E R+ ++ + F+ E + E P+APPK E S P P T+ A+
Sbjct: 10412 EHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEI--SEKIIPPKKPPTKVVPRKEPPAKV 10469
Query: 927 PEEKKKVKMRRKRRLPNKELSRELS-------KELNHEIQRTENSLANENQQPIKSEPES 979
PE KK+ + K R+P + KE+ E ++ A + + P PE+
Sbjct: 10470 PEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPE-KKVPVPPAKKPEAPPPKVPEA 10528
Query: 980 EGE---EPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCI 1036
E E K P ++P + P+ + PP+ S PP PK +
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV 10588
Query: 1037 QMERHVIRPPPISP 1050
E+ V PP P
Sbjct: 10589 VPEKKVPAAPPKKP 10602
Score = 31.6 bits (70), Expect = 5.3
Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 26/160 (16%)
Query: 408 LEMEEEACDQQ---PQEEEEKDEEGEGRDRAPKPPTDGSTSPTST--PSEDQEALGKKPK 462
L EEE ++ P+EE +EE + P + P P E++E ++
Sbjct: 10101 LPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEY 10160
Query: 463 APALRFLKRTLSNESEESVKSTTLAVDY-PKTPTGSPATEVSAKWTHLTEFELKGLKALV 521
P E EE V + + PK P +P E+ K T K ++
Sbjct: 10161 VP-----------EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEK--------KVVI 10201
Query: 522 EKLESLPENKKC-VPEGIEDPQALLEGVKNVLKEHADDDP 560
K E P K VP+ +E+ + +L + VL ++P
Sbjct: 10202 PKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEP 10241
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 47.4 bits (111), Expect = 9e-05
Identities = 63/284 (22%), Positives = 107/284 (37%), Gaps = 27/284 (9%)
Query: 749 KEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEK 808
+E+ +RD + + K RS E R R E ++ R + + ++R+ E+
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE-----RERERERERERERERER 417
Query: 809 PQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPG--KEDKLFR 866
+E + + R L L R +Q++LK +E K R
Sbjct: 418 EREREREREKDKKRDREEDEEDAYERRKLERKL----REKEAAYQERLKNWEIRERKKTR 473
Query: 867 KKRRSWKNAEDR---MALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEG 923
+ + + E+R MA K L+ F ++ +D+ + PK + E
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD--PKYYRGSALQKRLRDREKEMEA 531
Query: 924 AEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEE 983
E +++K ++ R+ L E + + E+QR E Q IK EPESE EE
Sbjct: 532 DERDRKREKEELEEIRQ----RLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587
Query: 984 PKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPP 1027
E+ + K E + P L+ R IS P
Sbjct: 588 E-------EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAP 624
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,631,465
Number of Sequences: 37866
Number of extensions: 3362989
Number of successful extensions: 24567
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 649
Number of HSP's that attempted gapping in prelim test: 19486
Number of HSP's gapped (non-prelim): 4756
length of query: 1336
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1222
effective length of database: 13,930,794
effective search space: 17023430268
effective search space used: 17023430268
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.