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Search of human proteins with 53831997
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]
(581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens] 1207 0.0
gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens] 172 6e-43
gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens] 84 3e-16
gi|40807480 suppressor of cytokine signaling 4 [Homo sapiens] 79 1e-14
gi|18254466 suppressor of cytokine signaling 4 [Homo sapiens] 79 1e-14
gi|195976771 cytokine-inducible SH2-containing protein isoform 1... 76 7e-14
gi|21614507 cytokine-inducible SH2-containing protein isoform 2 ... 76 7e-14
gi|21618354 suppressor of cytokine signaling 5 [Homo sapiens] 75 2e-13
gi|7662240 suppressor of cytokine signaling 5 [Homo sapiens] 75 2e-13
gi|45439352 suppressor of cytokine signaling 3 [Homo sapiens] 64 3e-10
gi|60460889 Myb protein P42POP [Homo sapiens] 61 2e-09
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 61 2e-09
gi|4507233 suppressor of cytokine signaling 1 [Homo sapiens] 56 8e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 2e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 54 3e-07
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 54 5e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 54 5e-07
gi|33286436 gametogenetin [Homo sapiens] 54 5e-07
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 53 7e-07
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 53 9e-07
gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta... 52 1e-06
gi|188536047 SWI/SNF-related matrix-associated actin-dependent r... 52 1e-06
gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo ... 52 2e-06
gi|16306552 semaphorin Y [Homo sapiens] 52 2e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 52 2e-06
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 52 2e-06
gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 51 3e-06
gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p5... 51 3e-06
>gi|53831997 suppressor of cytokine signaling 7 [Homo sapiens]
Length = 581
Score = 1207 bits (3124), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQL 60
MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQL
Sbjct: 1 MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQL 60
Query: 61 AALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGL 120
AALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGL
Sbjct: 61 AALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGL 120
Query: 121 ESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ 180
ESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ
Sbjct: 121 ESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ 180
Query: 181 QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGE 240
QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGE
Sbjct: 181 QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGE 240
Query: 241 LAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGL 300
LAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGL
Sbjct: 241 LAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGL 300
Query: 301 TSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA 360
TSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA
Sbjct: 301 TSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA 360
Query: 361 PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDG 420
PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDG
Sbjct: 361 PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDG 420
Query: 421 SFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIM 480
SFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIM
Sbjct: 421 SFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIM 480
Query: 481 HSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL 540
HSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL
Sbjct: 481 HSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL 540
Query: 541 PKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST 581
PKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST
Sbjct: 541 PKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST 581
>gi|21450785 suppressor of cytokine signaling 6 [Homo sapiens]
Length = 535
Score = 172 bits (437), Expect = 6e-43
Identities = 119/303 (39%), Positives = 159/303 (52%), Gaps = 24/303 (7%)
Query: 251 MGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPP 310
+GG A E ++ L F S + L G T V + + G P +P
Sbjct: 257 VGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTG--VMLQSPRAGHDDVPPLSPLL 314
Query: 311 PPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHS 370
PP ++ + + SG T VA +F P++ P +A R +S+ S
Sbjct: 315 PPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFD---------PNSAPGVA--RVYDSVQS 363
Query: 371 QPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDP 430
P + +S L++L K GWYWGP+ +AE KL PDGSFLVRDSSD
Sbjct: 364 SGPMVV---------TSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDD 414
Query: 431 RYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYF 490
RY+LSLSFRS G T HTR+EH G FS + P E S+V+ I+ +I S+NG F Y
Sbjct: 415 RYLLSLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGH-TSIVDLIEHSIRDSENGAFCY- 472
Query: 491 LRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRK 550
RSR+PG PV+L PVSRF V+SLQ+LCRF IRQ RID I LPLP + Y+++
Sbjct: 473 SRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQE 532
Query: 551 FYY 553
+Y
Sbjct: 533 KHY 535
>gi|4507263 suppressor of cytokine signaling-2 [Homo sapiens]
Length = 198
Score = 84.3 bits (207), Expect = 3e-16
Identities = 57/175 (32%), Positives = 87/175 (49%), Gaps = 13/175 (7%)
Query: 383 PDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQG 442
P ++ A +LREL + GWYWG M +A+ KLK P+G+FL+RDSS Y+L++S ++
Sbjct: 31 PQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSA 90
Query: 443 ITHHTRMEHYRGTF---SLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLP 499
+ R+E+ G F S+ C + SVV I + K+ + P P
Sbjct: 91 GPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKD-------KRTGPEAP 143
Query: 500 PT-PVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYY 553
V L +++ SLQHLCR I + I LPLP L Y+ ++ +
Sbjct: 144 RNGTVHLYLTKPLYTSAPSLQHLCRLTINKCT--GAIWGLPLPTRLKDYLEEYKF 196
>gi|40807480 suppressor of cytokine signaling 4 [Homo sapiens]
Length = 440
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/168 (31%), Positives = 78/168 (46%), Gaps = 15/168 (8%)
Query: 401 YWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWC 460
YWG M+ AE L+GKP+G+FL+RDS+ Y+ S+SFR + H R+E + FS
Sbjct: 287 YWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDA 346
Query: 461 HPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQH 520
H D C I + H K+ F L TP+ +P SLQH
Sbjct: 347 H----DPCVFHSPDITGLLEHYKDPSACMFFEP----LLSTPLIRTFPF-------SLQH 391
Query: 521 LCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQ 568
+CR I D I LP+P + Y+++++Y + + E Q
Sbjct: 392 ICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQ 439
>gi|18254466 suppressor of cytokine signaling 4 [Homo sapiens]
Length = 440
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/168 (31%), Positives = 78/168 (46%), Gaps = 15/168 (8%)
Query: 401 YWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWC 460
YWG M+ AE L+GKP+G+FL+RDS+ Y+ S+SFR + H R+E + FS
Sbjct: 287 YWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDA 346
Query: 461 HPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQH 520
H D C I + H K+ F L TP+ +P SLQH
Sbjct: 347 H----DPCVFHSPDITGLLEHYKDPSACMFFEP----LLSTPLIRTFPF-------SLQH 391
Query: 521 LCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQ 568
+CR I D I LP+P + Y+++++Y + + E Q
Sbjct: 392 ICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQ 439
>gi|195976771 cytokine-inducible SH2-containing protein isoform 1
[Homo sapiens]
Length = 275
Score = 76.3 bits (186), Expect = 7e-14
Identities = 54/191 (28%), Positives = 89/191 (46%), Gaps = 25/191 (13%)
Query: 384 DSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGI 443
D A + L + GWYWG + +A L+ P+G+FLVRDS+ P Y+ +LS ++
Sbjct: 83 DLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRG 142
Query: 444 THHTRMEHYRGTFSL----WCHPK---FEDRCQSVVEFIKRAIMHSKNGK-------FLY 489
+ R+E+ +F L P+ F D V ++ +++ L
Sbjct: 143 PTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALP 202
Query: 490 FLRSRVPGLPPTP---------VQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL 540
+ P P P ++L+ P R S+ +SLQHLCR I +LV + LPL
Sbjct: 203 MPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVA--DVDCLPL 260
Query: 541 PKPLISYIRKF 551
P+ + Y+R++
Sbjct: 261 PRRMADYLRQY 271
>gi|21614507 cytokine-inducible SH2-containing protein isoform 2
[Homo sapiens]
Length = 258
Score = 76.3 bits (186), Expect = 7e-14
Identities = 54/191 (28%), Positives = 89/191 (46%), Gaps = 25/191 (13%)
Query: 384 DSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGI 443
D A + L + GWYWG + +A L+ P+G+FLVRDS+ P Y+ +LS ++
Sbjct: 66 DLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRG 125
Query: 444 THHTRMEHYRGTFSL----WCHPK---FEDRCQSVVEFIKRAIMHSKNGK-------FLY 489
+ R+E+ +F L P+ F D V ++ +++ L
Sbjct: 126 PTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCTADTRSDSPDPAPTPALP 185
Query: 490 FLRSRVPGLPPTP---------VQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPL 540
+ P P P ++L+ P R S+ +SLQHLCR I +LV + LPL
Sbjct: 186 MPKEDAPSDPALPAPPPATAVHLKLVQPFVRRSSARSLQHLCRLVINRLVA--DVDCLPL 243
Query: 541 PKPLISYIRKF 551
P+ + Y+R++
Sbjct: 244 PRRMADYLRQY 254
>gi|21618354 suppressor of cytokine signaling 5 [Homo sapiens]
Length = 536
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 15/153 (9%)
Query: 401 YWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWC 460
YWG M+ +AE L+GKP+G+FL+RDS+ Y+ S+SFR + H R+E + FS
Sbjct: 382 YWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDA 441
Query: 461 HPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQH 520
H D C + + H K+ F L + +P SLQ+
Sbjct: 442 H----DPCVFHSSTVTGLLEHYKDPSSCMFFEP----LLTISLNRTFPF-------SLQY 486
Query: 521 LCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYY 553
+CR I + D I LPLP L ++++++Y
Sbjct: 487 ICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHY 519
>gi|7662240 suppressor of cytokine signaling 5 [Homo sapiens]
Length = 536
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 15/153 (9%)
Query: 401 YWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWC 460
YWG M+ +AE L+GKP+G+FL+RDS+ Y+ S+SFR + H R+E + FS
Sbjct: 382 YWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDA 441
Query: 461 HPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQH 520
H D C + + H K+ F L + +P SLQ+
Sbjct: 442 H----DPCVFHSSTVTGLLEHYKDPSSCMFFEP----LLTISLNRTFPF-------SLQY 486
Query: 521 LCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYY 553
+CR I + D I LPLP L ++++++Y
Sbjct: 487 ICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHY 519
>gi|45439352 suppressor of cytokine signaling 3 [Homo sapiens]
Length = 225
Score = 64.3 bits (155), Expect = 3e-10
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 30/179 (16%)
Query: 391 SLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME 450
++R+L++ G+YW + +A + L +P G+FL+RDSSD R+ +LS ++Q T + R++
Sbjct: 37 AVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQ 96
Query: 451 HYRGTFSLWCHPKFED---RCQSVVEFIKRAIMHSKNGKF------------LYFLRSRV 495
G+FSL P+ R V++ + + F +
Sbjct: 97 CEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPL 156
Query: 496 PGLPP------------TPVQLLYPVSRFSNVKSLQHLCRFRIR-QLVRIDHIPDLPLP 541
PG PP P+ L P+S SNV +LQHLCR + L + + LP P
Sbjct: 157 PGSPPRRAYYIYSGGEKIPLVLSRPLS--SNVATLQHLCRKTVNGHLDSYEKVTQLPGP 213
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 61.2 bits (147), Expect = 2e-09
Identities = 83/309 (26%), Positives = 103/309 (33%), Gaps = 80/309 (25%)
Query: 70 GPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQ---AGEDPTE--TSDALLVLEGLESEA 124
GPGV G G PP P QP PP+A PQ ED E +D + S
Sbjct: 121 GPGVAAPGAGA-GAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSP 179
Query: 125 ESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQ 184
E SC+ +E GG + PP L PV P L P
Sbjct: 180 EPWARPSCTPQE------GGCPRPKERESPPPSALQPVQLPRLALSP------------- 220
Query: 185 QQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAAS 244
P PP PPP PL +A S RP L+AS
Sbjct: 221 -PPPAPPLPPPPPLAQVA-----------------------PSPPSPPPPPRPPPTLSAS 256
Query: 245 AASLTDM-----GGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRG 299
SL + +A REL + L + A S + PL G V + +
Sbjct: 257 DPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS--ALLPLLPGTPVDSLPPPL---- 310
Query: 300 LTSPHPPTPPPPPRRSL-----------------SLLDDISGTLPTSVLVAPMGSSLQSF 342
P PP PPPPPR L + + D + V++AP
Sbjct: 311 ---PPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPR 367
Query: 343 PLPPPPPPH 351
P P P PPH
Sbjct: 368 PPPAPLPPH 376
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/196 (27%), Positives = 69/196 (35%), Gaps = 57/196 (29%)
Query: 17 AAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTV 76
A P P E CPR + + PP AL+ P L A L P P + V
Sbjct: 183 ARPSCTPQEGGCPRPK----ERESPPPSALQPVQLPRLALSPPPPAPPLPPP--PPLAQV 236
Query: 77 GGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPT--------ETSDALLVLEGLESEAESLE 128
P PP PPPP PP + DP+ ET++A+ L G + +
Sbjct: 237 A------PSPPSPPPPPRPPPTLS---ASDPSLDFLRAQQETANAIRELAGTLRQGLAKL 287
Query: 129 TNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQP 188
+ + S LL PG + +P PL P
Sbjct: 288 SEALSA---------------LLPLLPGTPVDSLPPPLPP-------------------P 313
Query: 189 PPPPPPPGPLRPLAGP 204
PPPPPPP P+ P P
Sbjct: 314 PPPPPPPRPVLPPPAP 329
Score = 37.4 bits (85), Expect = 0.038
Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 14/82 (17%)
Query: 84 PCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRG 143
P PP PPPP+P P AP+ P S V++G A + SEE P
Sbjct: 312 PPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRP--- 368
Query: 144 GGGGGRLLLQPPGPELPPVPFP 165
PP P LPP P
Sbjct: 369 ----------PPAP-LPPHDSP 379
Score = 37.0 bits (84), Expect = 0.050
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 30/90 (33%)
Query: 302 SPHPPTPPPPPR-------------------RSLSLLDDISGTLP----------TSVLV 332
+P PP+PPPPPR + + + +++GTL +++L
Sbjct: 237 APSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296
Query: 333 APMGSSLQSFPLP-PPPPPHAPDAFPRIAP 361
G+ + S P P PPPPP P P + P
Sbjct: 297 LLPGTPVDSLPPPLPPPPPPPPPPRPVLPP 326
Score = 31.6 bits (70), Expect = 2.1
Identities = 20/64 (31%), Positives = 26/64 (40%), Gaps = 19/64 (29%)
Query: 303 PHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPI 362
P PP PPPPP +A + S S P PP PPP + P + +
Sbjct: 223 PAPPLPPPPP-------------------LAQVAPSPPSPPPPPRPPPTLSASDPSLDFL 263
Query: 363 RAAE 366
RA +
Sbjct: 264 RAQQ 267
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 61.2 bits (147), Expect = 2e-09
Identities = 89/356 (25%), Positives = 115/356 (32%), Gaps = 62/356 (17%)
Query: 40 LPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAA 99
LPP A + PA + L + Q G GGG P P P P PQP P A
Sbjct: 1087 LPPRAASAAMYVPARSGRGRKGPL-VKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVA 1145
Query: 100 APQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPEL 159
AP ++ ++ S S + +S E + P GGGGG P P +
Sbjct: 1146 APSE-KNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAM 1204
Query: 160 PPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRP------------LAGPSRK 207
PVP P P P P P P L G +R+
Sbjct: 1205 SPVP----------------------PSPSPVPTPASPSGPATLDFTSQFGAALVGAARR 1242
Query: 208 -GSFK---IRLSRLFRTKSC--NGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDA 261
G ++ R S LF + G GG GTG P L S + +D
Sbjct: 1243 EGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHS------------KSIDE 1290
Query: 262 G---RKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTP--PPPPRRSL 316
G +P L R +SA S + G TS PP P P ++L
Sbjct: 1291 GMFSAEPYL-RLESAGSGAGYGGYGAGSRA--YGGGGGSSAFTSFLPPRPLVHPLTGKAL 1347
Query: 317 SLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQP 372
+ L S P PPP PP P P + H +P
Sbjct: 1348 DPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEP 1403
Score = 58.9 bits (141), Expect = 1e-08
Identities = 95/352 (26%), Positives = 124/352 (35%), Gaps = 55/352 (15%)
Query: 3 FRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLA-----LERTWGPAAGLE 57
F N PE P P P P L P PP +A L+ T +
Sbjct: 1573 FSNSFEKPESPLTPGPPHPLPDT---PAPATPLPPVP-PPAVAAAPPTLDSTASSLTSYD 1628
Query: 58 AQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDA-LLV 116
+++A L G A PG P PP PP P P AAPQ G DP +D+ +
Sbjct: 1629 SEVATLTQGASAAPGD----------PHPPGPPAP-AAPAPAAPQPGPDPPPGTDSGIEE 1677
Query: 117 LEGLESEAESLETNSCSE--EELSSPGRG--GGGGGRLLLQPPGPELPPVPFPLQDLVPL 172
++ S LET S + LS+ G G GGGGG GPEL D
Sbjct: 1678 VDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAF 1737
Query: 173 GRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDG 232
G S P PP PP + P K+R R +GG G
Sbjct: 1738 GGSS-----------TPGPPYPPQLMTP---------SKLR----GRALGASGGLRPGPS 1773
Query: 233 TGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVD 292
G R + S+T G L A P A PV+ P +
Sbjct: 1774 GGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGV--AGGPVAVEPEVPPVPLPTAS 1831
Query: 293 VDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPT--SVLVAPMGSSLQSF 342
+ ++ L P PPPPP L + L T + +++ + S LQ F
Sbjct: 1832 -SLPRKLLPWEEGPGPPPPPLPG-PLAQPQASALATVKASIISELSSKLQQF 1881
Score = 53.5 bits (127), Expect = 5e-07
Identities = 96/395 (24%), Positives = 123/395 (31%), Gaps = 49/395 (12%)
Query: 7 GRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPP-GLALERTWGPAAGLEAQLAALGL 65
GR P ED P P P + P P+A GL L PA ++ +
Sbjct: 1507 GRGPPSEDGPGVPPPSPRRSVPP---SPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLF 1563
Query: 66 GQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAE 125
+P P ++ P P P PP P P AP P L+S A
Sbjct: 1564 VEPLPPPLEFSNSFEKP-ESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS 1622
Query: 126 SLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQ 185
SL T+ SE + G G PPGP P P P Q
Sbjct: 1623 SL-TSYDSEVATLTQGASAAPGDP---HPPGPPAPAAPAP----------------AAPQ 1662
Query: 186 QQPPPPPPPPGPLRPLAG------PSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSG 239
P PPP + + P S LS L + G GGG G G
Sbjct: 1663 PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGP 1722
Query: 240 ELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRG 299
EL + + D G+ P +P G + L G
Sbjct: 1723 ELLDTYVAYLD-----GQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPG--PSGG 1775
Query: 300 LTSPHPPTPPP-----PPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPD 354
L P PT P L L SG V P+ + +PP P P A
Sbjct: 1776 LRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPE---VPPVPLPTASS 1832
Query: 355 AFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFA 389
++ P E PP L PL +P +S+ A
Sbjct: 1833 LPRKLLP---WEEGPGPPPPPLPGPLAQPQASALA 1864
Score = 47.8 bits (112), Expect = 3e-05
Identities = 95/412 (23%), Positives = 131/412 (31%), Gaps = 76/412 (18%)
Query: 7 GRPPEEEDVEAAPEPGPS---------ELLCPRHRCALDPKALPPGLALERTWGPAAGLE 57
G P AAP+PGP E + R + + L G
Sbjct: 1649 GPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSA 1708
Query: 58 AQLAALGLGQPAGPGV----------KTVGGGCCPCPCPPQPPPPQPQPPAA-------- 99
G G +GP + + GG P P P PPQ P+
Sbjct: 1709 GGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGP----PYPPQLMTPSKLRGRALGA 1764
Query: 100 ------APQAG-EDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLL 152
P G DP + + + G ++ L +CS P G GG + +
Sbjct: 1765 SGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDG-LLALRACS-----GPPTAGVAGGPVAV 1818
Query: 153 QPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKI 212
+P E+PPVP P +P L E P PPPP PLA P +
Sbjct: 1819 EP---EVPPVPLPTASSLPRKLLPWEEG---------PGPPPPPLPGPLAQPQASALATV 1866
Query: 213 RLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQS 272
+ S + S GG G S GG A P+ T
Sbjct: 1867 KASIISELSSKLQQFGGSSAAGGALPWARGGSG------GGGDSHHGGASYVPERT---- 1916
Query: 273 AFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDIS--GTLPTSV 330
S + L SL+ +S P PP PP P +S + T P++
Sbjct: 1917 --SSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSAS 1974
Query: 331 LVAPMGSSLQ--SFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPL 380
+ LQ F + PP AP P + P A+E S P+ P+
Sbjct: 1975 SSSTSTRHLQGVEFEMRPPLLRRAPS--PSLLP--ASEHKVSPAPRPSSLPI 2022
Score = 35.0 bits (79), Expect = 0.19
Identities = 92/411 (22%), Positives = 127/411 (30%), Gaps = 83/411 (20%)
Query: 12 EEDVEAAPEPGPSELLC-----------------PRHRCALD---PKALPPGLAL---ER 48
++ + A+ PGP L P HR P LPPG L ++
Sbjct: 830 QQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQK 889
Query: 49 TWGPAAGLEAQLA--ALGLGQPAG-PGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGE 105
+ G A LA A+ + PG + + PP P P+PP + P
Sbjct: 890 SIGAAEDDRPYLAPPAMKFSRSLSVPGSEDI---------PPPPTTSPPEPPYSTP---- 936
Query: 106 DPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFP 165
P +S L S SSP G PP +
Sbjct: 937 -PVPSSSGRLT---PSPRGGPFNPGSGGPLPASSPASFDGP------SPPDTRVGSREKS 986
Query: 166 LQDLVPLGRLSRGEQQQQQQQQPPPPP------PPPGPLRPLAGPSRKGSFKIRLSRLFR 219
L PL PPP P PP P G ++ L
Sbjct: 987 LYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALG---P 1043
Query: 220 TKSCNGGSGGGDG-TGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVS 278
S G GGG T PS SA G S G L + P + + + P
Sbjct: 1044 QPSLRGWRGGGPSPTPGAPSPSHHGSAGG--GGGSSQGPALRYFQLPPRAASAAMYVPAR 1101
Query: 279 FSPLFTGETVSLVDVD-ISQRG-----LTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLV 332
G V V+ Q+G SP P P PP + + S +PT ++
Sbjct: 1102 SGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIK 1161
Query: 333 AP---------MGSSLQSFPLPPPPPP-------HAPDAFPRIAPIRAAES 367
AP GSS ++ P P P +P P ++P+ + S
Sbjct: 1162 APSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPS 1212
>gi|4507233 suppressor of cytokine signaling 1 [Homo sapiens]
Length = 211
Score = 56.2 bits (134), Expect = 8e-08
Identities = 56/215 (26%), Positives = 83/215 (38%), Gaps = 37/215 (17%)
Query: 337 SSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELE 396
SS + P P P P P P R S H+ YR + + A L+
Sbjct: 30 SSSPAAPARPRPCPAVPAPAPGDTHFRTFRS-HAD---------YRRITRASAL----LD 75
Query: 397 KCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTF 456
CG+YWGP++ A +L+ +P G+FLVRDS +LS + R+ G F
Sbjct: 76 ACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRF 135
Query: 457 SLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVK 516
L D + + + + H P ++L R V+
Sbjct: 136 HL-------DGSRESFDCLFELLEH----------------YVAAPRRMLGAPLRQRRVR 172
Query: 517 SLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKF 551
LQ LCR RI V +++ +PL L Y+ F
Sbjct: 173 PLQELCRQRIVATVGRENLARIPLNPVLRDYLSSF 207
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/370 (26%), Positives = 126/370 (34%), Gaps = 62/370 (16%)
Query: 10 PEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPA 69
P V A P P ++L P A +P A+ AAG E A G +PA
Sbjct: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV------AAGPEP--APAGPAKPA 161
Query: 70 GPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLET 129
GP G P P P P P P PA A S ALL + A SL
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAA--QTLNGSAALLNSHHAAAPAVSLVN 219
Query: 130 NS-CSEEELSSPGRGGGGGGRLLLQPP-----GPELPPVPFPLQDLVPLGRLSRGEQQQQ 183
N + L P G ++ PP P P P P P +
Sbjct: 220 NGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA------- 268
Query: 184 QQQQPPPPPPPPGPL-RPLAGPSRKGSFKIRLSRLFRTKSCNGGS-----------GGGD 231
PPPPPP P L RP P+ + + + NGGS GG
Sbjct: 269 ---APPPPPPAPATLARPPGHPAGPPTAAPAVPP--PAAAQNGGSAGAAPAPAPAAGGPA 323
Query: 232 GTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLV 291
G +P AA+A + S R + A P +T +A P S S+V
Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAA--PPAAQTLAASGPAS-------TAASMV 374
Query: 292 DVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAP------MGSSLQSFPLP 345
Q L SP PPP P L +G + S+ P + ++L L
Sbjct: 375 IGPTMQGALPSP-AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433
Query: 346 P--PPPPHAP 353
P P PP P
Sbjct: 434 PRLPQPPQNP 443
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/241 (25%), Positives = 78/241 (32%), Gaps = 51/241 (21%)
Query: 145 GGGGRLLLQPPGPELPPVPF----PLQDLVPLGRLSRGE---QQQQQQQQPPPPPPPPGP 197
GGGG PP P P VP P L P S G P P P GP
Sbjct: 98 GGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGP 157
Query: 198 LRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGR 257
+P AGP + L G G G G G P G+ A A+ T G +A
Sbjct: 158 AKP-AGP----------AALAARAGPGPGPGPGPGPGPGP-GKPAGPGAAQTLNGSAALL 205
Query: 258 ELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLS 317
P ++ + P + PL V G +P P P PP
Sbjct: 206 NSHHAAAPAVSLVNN--GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP----- 258
Query: 318 LLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHA-----------PDAFPRIAPIRAAE 366
AP ++ + P PPPP P P A P + P AA+
Sbjct: 259 --------------AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304
Query: 367 S 367
+
Sbjct: 305 N 305
Score = 31.2 bits (69), Expect = 2.7
Identities = 43/160 (26%), Positives = 60/160 (37%), Gaps = 20/160 (12%)
Query: 42 PGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAP 101
P L+R+ G++ QL G Q A G T P + P +AA
Sbjct: 536 PSATLQRS----PGVQPQLVLGGAAQTASLGTATA----VQTGTPQRTVPGATTTSSAAT 587
Query: 102 QAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGG--------RLLLQ 153
+ E+ + + L L L S + + + +EL G R L
Sbjct: 588 ETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNS 647
Query: 154 PPGPELPPVPFPLQDLVPLGRLSRGEQQ--QQQQQQPPPP 191
P P L VPF + L L +L+ QQ QQQPPPP
Sbjct: 648 SPQPYL--VPFLKRSLPALRQLTPDSAAFIQQSQQQPPPP 685
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 54.7 bits (130), Expect = 2e-07
Identities = 68/252 (26%), Positives = 85/252 (33%), Gaps = 45/252 (17%)
Query: 15 VEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVK 74
++A P PS P + P A PP + + P + LAA L P P
Sbjct: 436 LQAPFSPPPS----PPVQAPFSPPASPP---VSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 75 TVGGGCCPCPCPPQPPPPQPQPPAAAP--QAGEDPTETSDALLV--LEGLESEAESLETN 130
P P PPPQ PP AAP Q + P + AL L+ L S S
Sbjct: 489 -------PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
Query: 131 SCSEEELSSPGRGGGGGGRLLLQPPGPELPPV-PFPLQDLVPLGRLSRGEQQQQQQQQP- 188
+ S P L P P+ PPV PL + P S Q ++ P
Sbjct: 542 APFSPSASLPMSP--------LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Query: 189 -----------------PPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGD 231
PPPPP P L+GP G S + + G GG
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 653
Query: 232 GTGKRPSGELAA 243
P ELAA
Sbjct: 654 AASPPPDAELAA 665
Score = 48.5 bits (114), Expect = 2e-05
Identities = 96/395 (24%), Positives = 126/395 (31%), Gaps = 78/395 (19%)
Query: 34 ALDPKALPPGLALERTWG----PAAGLEAQLAALGLG-----QPAGPGVKTVGGGCCPCP 84
A P A PGL R G P A L LG +P +GG P
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 85 CPPQPPP---------PQPQPPAA-----APQA-----------GEDPTETSDALLVLEG 119
P P P +PPA+ AP A G T L +G
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 120 LESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGE 179
L AE + E +P R G GP P P P ++R
Sbjct: 134 LRISAEETVARGKATE---APKRSALSAGARR-DTSGPT-PGTPSPA--------MARRS 180
Query: 180 QQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSG 239
+ + P P P P P GP + S S + + G G + S
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 240 ELAASAASLTDMGGSAG-----------------RELDAGRKPKLTRTQS----AFSPVS 278
L++SA L+ S + L A R P++T + A P+S
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 279 FSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSS 338
SPL T + L S PPT P P S SL ++ LP + S
Sbjct: 301 SSPLATPSPSA---------ALQSQAPPTLPATPHSS-SLTCQLATPLPLAPPSPSAPPS 350
Query: 339 LQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPP 373
LQ+ P PP PP ++A S PP
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385
Score = 40.4 bits (93), Expect = 0.005
Identities = 74/326 (22%), Positives = 103/326 (31%), Gaps = 35/326 (10%)
Query: 87 PQPPPPQPQPPAAAPQAGED-----PTETSDALLVLEGLESEAESLETNSCSEEELSSPG 141
P P P P + AG + P ++ EG S +S +E ++
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 142 RGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPL 201
R GGG L +P L PL G +RG + P P P
Sbjct: 227 RPSAGGG--LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 202 AGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDM---------- 251
P RK + L L + + P+ ++SLT
Sbjct: 285 VTPPRKDAAPA-LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 252 GGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPP-- 309
SA L P T A + + SP L +S L +P P PP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFLPSPPLSP--LATPPPQAPPAL 400
Query: 310 ----------PPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRI 359
PP LS L S P ++ V + + P PP P +P A P +
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 360 APIRAAESLHSQPPQHLQCPLYRPDS 385
+P +A PP PL P S
Sbjct: 461 SP--SATPPSQAPPSLAAPPLQVPPS 484
Score = 36.6 bits (83), Expect = 0.065
Identities = 50/202 (24%), Positives = 62/202 (30%), Gaps = 29/202 (14%)
Query: 8 RPPEEEDV--EAAPEPGP---SELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAA 62
RPP+ +AAP GP S L P AL +A P A + L L
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 63 LGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLES 122
A P ++T+ P PP PP Q +P L++
Sbjct: 341 APPSPSAPPSLQTL-------PSPPATPPSQATTSLGSPT-----------------LQA 376
Query: 123 EAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQ 182
L + S P L PP P P PL P +
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 183 QQQQQPPPPPPPPGPLRPLAGP 204
Q PPP PP P P A P
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASP 458
Score = 35.0 bits (79), Expect = 0.19
Identities = 99/396 (25%), Positives = 126/396 (31%), Gaps = 94/396 (23%)
Query: 8 RPPEE---EDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALG 64
RPP E + V +A E +E P P A G L+R A +A
Sbjct: 199 RPPTEGPRKSVSSASEHSTTE---PSPAARRRPSA---GGGLQRP----ASRSLSSSATP 248
Query: 65 LGQPAGPGVKTVGGGCCPC-PCPPQPP------PPQPQPPA--AAPQAG---EDPTETSD 112
L PA G G P P P+P PPQ PP AAP G P T
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 113 ALLVLEGLESEAESLETNSCSEE-ELSSPGRGGGGGGRLLLQPPGPELPP----VPFPLQ 167
L+ +S S +L++P L L PP P PP +P P
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATP---------LPLAPPSPSAPPSLQTLPSPPA 359
Query: 168 DLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGS 227
S G Q P PP L PLA P + + L L
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPP----LSPLATPPPQAPPALALPPLQAP------- 408
Query: 228 GGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGET 287
PS + + L A L + Q+ FSP P+
Sbjct: 409 ---------PSPPASPPLSPLATPSPQAPNAL------AVHLLQAPFSPPPSPPV----- 448
Query: 288 VSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPP 347
+ SP P +PP P S T P+ + LQ P PP
Sbjct: 449 ----------QAPFSP-PASPPVSP----------SATPPSQAPPSLAAPPLQVPPSPPA 487
Query: 348 PPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRP 383
PP +P A P P +A L + P Q + P P
Sbjct: 488 SPPMSPSATP---PPQAPPPLAAPPLQLAKPPPQAP 520
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 54.7 bits (130), Expect = 2e-07
Identities = 68/252 (26%), Positives = 85/252 (33%), Gaps = 45/252 (17%)
Query: 15 VEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVK 74
++A P PS P + P A PP + + P + LAA L P P
Sbjct: 397 LQAPFSPPPS----PPVQAPFSPPASPP---VSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 75 TVGGGCCPCPCPPQPPPPQPQPPAAAP--QAGEDPTETSDALLV--LEGLESEAESLETN 130
P P PPPQ PP AAP Q + P + AL L+ L S S
Sbjct: 450 -------PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502
Query: 131 SCSEEELSSPGRGGGGGGRLLLQPPGPELPPV-PFPLQDLVPLGRLSRGEQQQQQQQQP- 188
+ S P L P P+ PPV PL + P S Q ++ P
Sbjct: 503 APFSPSASLPMSP--------LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554
Query: 189 -----------------PPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGD 231
PPPPP P L+GP G S + + G GG
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 614
Query: 232 GTGKRPSGELAA 243
P ELAA
Sbjct: 615 AASPPPDAELAA 626
Score = 53.1 bits (126), Expect = 7e-07
Identities = 97/380 (25%), Positives = 127/380 (33%), Gaps = 56/380 (14%)
Query: 34 ALDPKALPPGLALERTWG----PAAGLEAQLAALGLG-----QPAGPGVKTVGGGCCPCP 84
A P A PGL R G P A L LG +P +GG P
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 85 CPPQPPPPQPQPPAA-----APQA-----------GEDPTETSDALLVLEGLESEAESLE 128
P P +PPA+ AP A G T L +GL AE
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 129 TNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQP 188
+ E +P R G GP P P P ++R + +
Sbjct: 134 ARGKATE---APKRSALSAGARR-DTSGPT-PGTPSPA--------MARRSRAAGTEVGL 180
Query: 189 PPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASL 248
P P P P P GP + S S + + G G + S L++SA L
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240
Query: 249 TDMGGSAGRELDAGRKP-----KLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSP 303
+ S R P + A P +P +L + S SP
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 304 H-PPTPPPPPRRSLSLLDDISGTLP---TSVLVAPMGSSLQSF-PLPP-----PPPPHAP 353
PP+P PP SL L T P T+ L +P + SF P PP PPP AP
Sbjct: 301 SAPPSPSAPP--SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358
Query: 354 DAFPRIAPIRAAESLHSQPP 373
A + P++A S + PP
Sbjct: 359 PAL-ALPPLQAPPSPPASPP 377
Score = 44.3 bits (103), Expect = 3e-04
Identities = 73/312 (23%), Positives = 99/312 (31%), Gaps = 37/312 (11%)
Query: 87 PQPPPPQPQPPAAAPQAGED-----PTETSDALLVLEGLESEAESLETNSCSEEELSSPG 141
P P P P + AG + P ++ EG S +S +E ++
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 142 RGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPP-------PPP 194
R GGG L +P L PL G +RG + P P PP
Sbjct: 218 RPSAGGG--LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275
Query: 195 PGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGS 254
P R A P+ L+ + S PS + + T +G
Sbjct: 276 VTPPRKDAAPALGPLSSSPLAT--PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS- 332
Query: 255 AGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRR 314
P L T S SPL T + L P PP PP
Sbjct: 333 ----------PTLQATHSFLPSPPLSPLATPPPQA-------PPALALPPLQAPPSPPAS 375
Query: 315 S-LSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPP 373
LS L S P ++ V + + P PP P +P A P ++P +A PP
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP--SATPPSQAPP 433
Query: 374 QHLQCPLYRPDS 385
PL P S
Sbjct: 434 SLAAPPLQVPPS 445
Score = 39.7 bits (91), Expect = 0.008
Identities = 85/326 (26%), Positives = 109/326 (33%), Gaps = 49/326 (15%)
Query: 82 PCPCPP-QPPPPQPQPPAAAPQAGE-DPTETSDALLVLE----GLESEAESLETNSCSEE 135
P P P +P PP P + A E TE S A GL+ A + S S
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS--RSLSSSAT 238
Query: 136 ELSSPGRGGG---GGGRLLLQPPGPEL--------PPVPFPLQDLVP-LGRLSRGEQQQQ 183
LSSP R G G R P P+ P V P +D P LG LS
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298
Query: 184 QQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAA 243
PP P PP L+ L P T + G T + L +
Sbjct: 299 SPSAPPSPSAPPS-LQTLPSPPA-------------TPPSQATTSLGSPTLQATHSFLPS 344
Query: 244 SAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSP 303
L+ + + A P L S + SPL T + + +
Sbjct: 345 PP--LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Query: 304 HPPTPP------PPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFP 357
PP+PP PP +S P S+ P LQ P PP PP +P A P
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPPSPPASPPMSPSATP 458
Query: 358 RIAPIRAAESLHSQPPQHLQCPLYRP 383
P +A L + P Q + P P
Sbjct: 459 ---PPQAPPPLAAPPLQLAKPPPQAP 481
Score = 36.2 bits (82), Expect = 0.085
Identities = 92/366 (25%), Positives = 115/366 (31%), Gaps = 50/366 (13%)
Query: 8 RPPEE---EDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALG 64
RPP E + V +A E +E P P A G L+R A +A
Sbjct: 190 RPPTEGPRKSVSSASEHSTTE---PSPAARRRPSA---GGGLQRP----ASRSLSSSATP 239
Query: 65 LGQPAGPGVKTVGGGCCPC-PCPPQPP------PPQPQPPA--AAPQAGEDPTETSDALL 115
L PA G G P P P+P PPQ PP AAP G P +S
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG--PLSSSPLAT 297
Query: 116 VLEGLE---SEAESLETNSCSEEELSSPGRGGGGGGRLLLQP-----PGPELPPVPFPLQ 167
S SL+T + P + G LQ P P L P+ P
Sbjct: 298 PSPSAPPSPSAPPSLQT--LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 168 DLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGS 227
P L Q PP PP PL PLA PS + + + L S
Sbjct: 356 QAPPALALP--------PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 228 GGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGET 287
S ++ SA + S P L S + SP T
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLA-------APPLQVPPSPPASPPMSPSATPPP 460
Query: 288 VSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPP 347
+ + L P P PP L L + P +P +SL PL P
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP-SASLPMSPLATP 519
Query: 348 PPPHAP 353
PP P
Sbjct: 520 PPQAPP 525
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 54.3 bits (129), Expect = 3e-07
Identities = 61/222 (27%), Positives = 78/222 (35%), Gaps = 30/222 (13%)
Query: 157 PELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPG---PLRPLAGPSRKGSFKIR 213
P++PP P PL PL S G Q Q PPPPPP PG P P GP S +
Sbjct: 280 PKVPPTPEPL----PLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDL- 334
Query: 214 LSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSA 273
S S GG G P+ A +A + GG D P A
Sbjct: 335 -----APNSVGAASTGGGTGGTHPNTPTATTANNPLPPGG------DPSSAPGPALLGEA 383
Query: 274 FSPVSFSPLFTG-ETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLV 332
+P + G E +S ++ +R L + R + L SG +
Sbjct: 384 AAPGNGQRSLVGSEGLSKEQLEHRERSLQT----------LRDIERLLLRSGETEPFLKG 433
Query: 333 APMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQ 374
P G+ P PPPP P P + E L S Q
Sbjct: 434 PPGGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQ 475
Score = 45.8 bits (107), Expect = 1e-04
Identities = 72/296 (24%), Positives = 99/296 (33%), Gaps = 48/296 (16%)
Query: 84 PCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRG 143
P P PPPPQ P + S+ + NS + + SP
Sbjct: 1122 PLLPPPPPPQGSGPGIS--------------------NSQPSQMHLNSAAAQ---SPMGM 1158
Query: 144 GGGGGRLLLQPPGPELPPVPFPLQDLVPL---GRLSRGEQQQQQQQQPPPPPPPPGPLRP 200
G + L P P + P P PL +PL + + G Q P P P P
Sbjct: 1159 NLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGP 1218
Query: 201 LAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKR-PSGELAASAASLTDMGGSAGREL 259
+ S+ F RL + + GG GGG G + PSG G +
Sbjct: 1219 VPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQ 1278
Query: 260 DAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLL 319
K R A+ P + G L D ++S+ PTP P
Sbjct: 1279 HLMGKAMAGRMGDAYPP----GVLPGVASVLNDPELSE-----VIRPTPTGIPE------ 1323
Query: 320 DDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHA--PDAFPRIAPIRAAESLHSQPP 373
D+S +P+ S+LQ FP PP A P+ AE S+PP
Sbjct: 1324 FDLSRIIPSE----KPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPP 1375
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/202 (26%), Positives = 69/202 (34%), Gaps = 21/202 (10%)
Query: 10 PEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPA 69
P+ + P P P+ P AL P+ PP + + + G + G P
Sbjct: 299 PQSQPPPLPPPPPPAPGSAPP---ALPPEG-PPEDSSQDLAPNSVGAASTGGGTGGTHPN 354
Query: 70 GPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLET 129
P T P P P P AAAP G+ S+ L E LE SL+T
Sbjct: 355 TPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSK-EQLEHRERSLQT 413
Query: 130 ----------NSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGE 179
+ +E L P G G GG PP P+ PP P L +
Sbjct: 414 LRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTA-PPSGLKKYEEPLQSM 472
Query: 180 QQQQQQQQPPP-----PPPPPG 196
Q Q PP P PPG
Sbjct: 473 ISQTQSLGGPPLEHEVPGHPPG 494
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 53.5 bits (127), Expect = 5e-07
Identities = 47/140 (33%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 77 GGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEE 136
G G P P PP PPP P PAA+P DP S GL S + E
Sbjct: 775 GRGPPPAPPPPPPPPRAPADPAASP----DP--PSAVASPGSGLSSPGPKPGDSGYETET 828
Query: 137 LSSP-GRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPP 195
SP G GGG P P PP P P PPP P
Sbjct: 829 PFSPEGAFPGGGAAEEEGVPRPRAPPEP--------------------PDPGAPRPPPDP 868
Query: 196 GPLRPLAGPSRKGSFKIRLS 215
GPL PL GP K +F +++S
Sbjct: 869 GPL-PLPGPREKPTFVVQVS 887
Score = 46.6 bits (109), Expect = 6e-05
Identities = 101/397 (25%), Positives = 131/397 (32%), Gaps = 81/397 (20%)
Query: 6 VGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGL-------ALER----TWGPAA 54
+G P E +E AP PS ++ R+ P L P ER T G
Sbjct: 1072 IGEPAPETSLERAP--APSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPR 1129
Query: 55 GLEAQLAALGLG--QPAGPGVKTVGG---------GCCPCPCPPQPPPPQPQPPAAAPQA 103
A LG G P G G GG G P PPPP P PP A P+
Sbjct: 1130 APGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRR 1189
Query: 104 GEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPEL--PP 161
E + + EG E + ++ + + LS G PP PE P
Sbjct: 1190 LEPAPPRARPEVAPEG---EPGAPDSRAGGDTALSGDG-----------DPPKPERKGPE 1235
Query: 162 VPFPLQDLVPLGRLSRGEQQQQQQQ-------QPP---PPPPPPGPLRPLAGPSRKGSFK 211
+P DL P +G +Q + + PP P P PGP RP + G
Sbjct: 1236 MPRLFLDLGP----PQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAG--- 1288
Query: 212 IRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQ 271
+ G +GG G D +A R P R +
Sbjct: 1289 ----------AAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGP--GRAR 1336
Query: 272 SAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLS--------LLDDIS 323
+A PV S L + S RG P + R+ +S L D +
Sbjct: 1337 AAPVPVVVSSADADAARPLRGLLKSPRGADEPE-DSELERKRKMVSFHGDVTVYLFDQET 1395
Query: 324 GTLPTSVLVAPMGSSLQSFPLPPPPPPHAP---DAFP 357
T SV P G + S P PP PPH D FP
Sbjct: 1396 PTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFP 1432
Score = 43.5 bits (101), Expect = 5e-04
Identities = 95/389 (24%), Positives = 122/389 (31%), Gaps = 92/389 (23%)
Query: 82 PCPCPPQPPP-----PQPQPPA-AAPQAGE-----------DPTETSDALLVLEGLESEA 124
P P PP PPP P P PPA +AP+ G + D L V E +
Sbjct: 446 PRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTE----SS 501
Query: 125 ESLETNSCSEEELSSPGRGGGG-GGRLLLQPPGPEL-PPVPF----------PLQDLVPL 172
L E+ GRGGG + PP P P PF P+
Sbjct: 502 RGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSP 561
Query: 173 GRLSRGEQQQQQQQQPPPP-------------PPPPGPLRPLAGP----SRKGSFKIRLS 215
S + ++ PP P P P P P P S
Sbjct: 562 SVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAP 621
Query: 216 RLFRTKSCNGGS---GGGDGTGKRPSGELAASAASLTDMGGSA-----GRELDAGRKPKL 267
R F +S GS G D G+ LA A + G+A E + G P
Sbjct: 622 RPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGE 681
Query: 268 TRTQSAFSP----------------VSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPP 311
+ P S PL G+ V+ L PHPP
Sbjct: 682 DSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWG---GHPALGCPHPPEDDSS 738
Query: 312 PRRSLSLLDDI----SGTLPTSVLVAPMGSSLQSF--------PLPPPPPPHAPDAFPRI 359
R L D+ + P L MG++ + P PPPPPP AP A P
Sbjct: 739 LRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAP-ADPAA 797
Query: 360 APIRAAESLHSQPPQHLQCPLYRPDSSSF 388
+P S + P L P +P S +
Sbjct: 798 SP--DPPSAVASPGSGLSSPGPKPGDSGY 824
Score = 33.9 bits (76), Expect = 0.42
Identities = 67/282 (23%), Positives = 90/282 (31%), Gaps = 42/282 (14%)
Query: 86 PPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGG 145
P P P PQ P A + + +ET + L A+S + S LS G
Sbjct: 588 PLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFL---LSGWDPEGR 644
Query: 146 GGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPS 205
G G L P L G ++++++ P GPS
Sbjct: 645 GAGETLAGDPAEVL-------------GERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPS 691
Query: 206 RKGSFKIRLSRLFRTKSCNGGSGGGD--GTGKRPSGELAASAASLTDMGGSAGRELDAGR 263
R+G L SC G G G P+ + + G D
Sbjct: 692 RRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPM 751
Query: 264 KPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDIS 323
P P S P F + RG PP PPPPP + D +
Sbjct: 752 AP----------PASAPPEFLDPLMGAAAPQYPGRG----PPPAPPPPPPPPRAPADPAA 797
Query: 324 GTLPTSVLVAPMGSSLQSFPLPPP-------PPPHAPD-AFP 357
P S + +P GS L S P P P P +P+ AFP
Sbjct: 798 SPDPPSAVASP-GSGLSS-PGPKPGDSGYETETPFSPEGAFP 837
Score = 33.9 bits (76), Expect = 0.42
Identities = 27/93 (29%), Positives = 33/93 (35%), Gaps = 2/93 (2%)
Query: 157 PELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPP--GPLRPLAGPSRKGSFKIRL 214
P PP P + L PL + + + PPPPPPP P P A P +
Sbjct: 750 PMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPG 809
Query: 215 SRLFRTKSCNGGSGGGDGTGKRPSGELAASAAS 247
S L G SG T P G A+
Sbjct: 810 SGLSSPGPKPGDSGYETETPFSPEGAFPGGGAA 842
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/212 (26%), Positives = 79/212 (37%), Gaps = 37/212 (17%)
Query: 7 GRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLG 66
G+PP+ + P P P + P + + PP P G ++Q G
Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 160
Query: 67 QPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAES 126
+P GP + GG P PP P P+ PP Q+ P + E
Sbjct: 161 KPEGPPPQ--GGNQSQGP-PPHPGKPEGPPPQGGNQSQGPPPRPG---------KPEGPP 208
Query: 127 LETNSCSEEELSSPGRGGG----GGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQ 182
+ + S+ PG+ G GG + PP P P P P Q+
Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPP--------------QEG 254
Query: 183 QQQQQPPPP-----PPPPG--PLRPLAGPSRK 207
+ Q+PPPP PPPPG P +PL P+ K
Sbjct: 255 NKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGK 286
Score = 40.0 bits (92), Expect = 0.006
Identities = 70/301 (23%), Positives = 93/301 (30%), Gaps = 56/301 (18%)
Query: 66 GQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAE 125
G+P G + GG P PP P P+ +PP Q+ P + E
Sbjct: 34 GKPEG---RRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPG---------KPEGP 81
Query: 126 SLETNSCSEEELSSPGRGGG----GGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQ 181
+ + S+ PG+ G GG + PP P P P P G S+G
Sbjct: 82 PPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG-----GNQSQGPPP 136
Query: 182 QQQQQQPPPPP-------PPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTG 234
+ + + PPP PPP P +P P + G+ GG G
Sbjct: 137 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQG 196
Query: 235 KRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVD 294
P GG+ + G P+ + + S P
Sbjct: 197 PPPR---PGKPEGPPPQGGNQSQ----GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGP 249
Query: 295 ISQRGLTSPHPPTP-----PPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPP 349
Q G PP P PPPP G P L P G P PPPP
Sbjct: 250 PPQEGNKPQRPPPPGRPQGPPPP-----------GGNPQQPLPPPAGK-----PQGPPPP 293
Query: 350 P 350
P
Sbjct: 294 P 294
Score = 30.8 bits (68), Expect = 3.6
Identities = 28/101 (27%), Positives = 37/101 (36%), Gaps = 14/101 (13%)
Query: 7 GRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLG 66
G PP+ + P P P + P + P+ PP + P G + Q
Sbjct: 206 GPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ------- 258
Query: 67 QPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDP 107
+P PG + G P PP P QP PP A G P
Sbjct: 259 RPPPPG-RPQG------PPPPGGNPQQPLPPPAGKPQGPPP 292
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 53.5 bits (127), Expect = 5e-07
Identities = 104/427 (24%), Positives = 139/427 (32%), Gaps = 84/427 (19%)
Query: 4 RNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAAL 63
R G PP ++ P P L + P PP L TW P L ++
Sbjct: 131 RGQGDPPSLRPLKPPPPP---RQLSVKDTVPRAPSQFPPPL---ETWKPPPPLPSER--- 181
Query: 64 GLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPP-------------AAAPQAGE----D 106
QPA + P P PP + Q A P AGE
Sbjct: 182 ---QPADRRIT-------PALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQ 231
Query: 107 PTETSDALLVLEGLESEAE-SLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPV--- 162
P ++ L +L + ++ SL + S + GGGGGG L V
Sbjct: 232 PADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQ 291
Query: 163 -PFPLQDLVPLGRLSRGEQQQQ------QQQQPPPPPP-------PPGPLRPLAGPSRKG 208
P P PLG +SRG Q+ + + PP P PP P G K
Sbjct: 292 GPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKF 351
Query: 209 SFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAG---RELDAGRKP 265
+ R NG +GGG G +R AA+L+ GS ++ + P
Sbjct: 352 DWVSAPDGPERHFRFNG-AGGGIGAPRR-------RAAALSGPWGSPPPPPEQIHSAPGP 403
Query: 266 KLTRTQSAFSPVSFSPLFT-GETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISG 324
+ P P T GE + + + PP PPP P +L
Sbjct: 404 RRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQEL------PPLPPPTPPPTLQP----PA 453
Query: 325 TLPTSVLVAP--------MGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHL 376
PT + VAP S+L P PP A D P +P A PP
Sbjct: 454 LQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSA 513
Query: 377 QCPLYRP 383
P P
Sbjct: 514 PAPAAAP 520
Score = 36.6 bits (83), Expect = 0.065
Identities = 40/145 (27%), Positives = 52/145 (35%), Gaps = 15/145 (10%)
Query: 9 PPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQP 68
PP +++ P P P L P AL P LP L G A AA P
Sbjct: 431 PPGLQELPPLPPPTPPPTLQPP---ALQPTPLPVAPPLTPGLGHKESALAPTAA-----P 482
Query: 69 AGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTET----SDALLVLEGLESEA 124
A P P P P P +P PP +AP P +T + G +
Sbjct: 483 ALPPALAADQAPAPSPAPA-PTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARG-ATRK 540
Query: 125 ESLETNSCSEEELSS-PGRGGGGGG 148
+ L + E ++ P GGGGG
Sbjct: 541 DGLHGDGPRERATATVPDSSGGGGG 565
Score = 34.7 bits (78), Expect = 0.25
Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 11/87 (12%)
Query: 293 VDISQRGLTSPHP--PTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPP 350
++ S RG P P PPPP R LS+ D T+P + P L+++ PPP P
Sbjct: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKD----TVPRAPSQFP--PPLETWKPPPPLPS 179
Query: 351 HAPDAFPRIAPIRAAESLHSQPPQHLQ 377
A RI P A + PP Q
Sbjct: 180 ERQPADRRITPALATP---ASPPTESQ 203
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 53.1 bits (126), Expect = 7e-07
Identities = 76/309 (24%), Positives = 109/309 (35%), Gaps = 61/309 (19%)
Query: 55 GLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQP-----QPPAAAPQAGEDPTE 109
G++ A G QPA G T+ P PP PP P + + PT
Sbjct: 152 GVKWLKAKHGNNQPARTG--TLSRTNPPTQKPPSPPMSGRGTLGRNTPYKTLEPVKPPTV 209
Query: 110 TSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELP-PVPFPLQD 168
+D + L S+ T S ++ + G GG G R +P VP P
Sbjct: 210 PNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPP 269
Query: 169 LVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSG 228
+ +S PP PP PL PL + +S + GS
Sbjct: 270 TIGPENIS---------VPPPSGAPPAPPLAPL----------LPVSTVIAAPGSAPGSQ 310
Query: 229 GGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETV 288
G T + S S T GG R P +T SA V+ PL++ ++
Sbjct: 311 YGTMTRQISRHN---STTSSTSSGGYR-------RTPSVTAQFSAQPHVNGGPLYSQNSI 360
Query: 289 SLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPP 348
S+ PPPPP + ++ +P + VA + ++ P PPPP
Sbjct: 361 SIA----------------PPPPP------MPQLTPQIPLTGFVARVQENIADSPTPPPP 398
Query: 349 PPHAPDAFP 357
PP PD P
Sbjct: 399 PP--PDDIP 405
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 52.8 bits (125), Expect = 9e-07
Identities = 85/365 (23%), Positives = 126/365 (34%), Gaps = 56/365 (15%)
Query: 10 PEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLAL---ERTWGPAAGLEAQLAALGLG 66
PEE AA P P E P + P A+ E PAA +
Sbjct: 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP------E 1050
Query: 67 QPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAES 126
+P P P P P +P PAAA E+PT + A+ E S A +
Sbjct: 1051 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1110
Query: 127 LETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPP-----VPFPLQDLVPLGRLSRGEQQ 181
+ T EE +SP P PE P VP P + P + E+
Sbjct: 1111 VPT----PEEPASPAAA----------VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEES 1156
Query: 182 QQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGEL 241
P P P + P+ SF ++ L S P+ +
Sbjct: 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS--------------PAASV 1202
Query: 242 ---AASAASLTDMGGSAGR----ELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVD 294
AA A+L + A E A ++ + SP + P T S V
Sbjct: 1203 PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV- 1261
Query: 295 ISQRGLTSPHP--PTPPPP--PRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPP 350
++ L+SP PTP P P ++S L++ + P + + P +++ + +P P P
Sbjct: 1262 LTPEELSSPAASVPTPEEPASPAAAVSNLEEPAS--PAAAVPTPEVAAIPAASVPTPEVP 1319
Query: 351 HAPDA 355
P A
Sbjct: 1320 AIPAA 1324
Score = 38.9 bits (89), Expect = 0.013
Identities = 56/229 (24%), Positives = 74/229 (32%), Gaps = 44/229 (19%)
Query: 11 EEEDVEAAPEPGPSELLCPRHRCAL-----------DPKALPPGLALERT---WGPAAGL 56
EEEDV AA P P ++ P+ P +A T AG
Sbjct: 892 EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951
Query: 57 EAQLAALGLGQPAGPGVKTVGGGCCPCP---CPPQPP--------PPQPQPPAAAPQAGE 105
+ AAL + P T G P P +P P +P PAAA E
Sbjct: 952 SPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE 1011
Query: 106 DPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELP----- 160
+PT + A+ E S A ++ EE +SP P PE P
Sbjct: 1012 EPTSPAAAVPTPEEPTSPAAAVP----PPEEPTSPAAA----------VPTPEEPTSPAA 1057
Query: 161 PVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGS 209
VP P + P + E+ P P P P + P S
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
Score = 37.0 bits (84), Expect = 0.050
Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 20/145 (13%)
Query: 9 PPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLAL---ERTWGPAAGL----EAQLA 61
PPEE AA P P E P + P A+ E PAA + E
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094
Query: 62 ALGLGQPAGPGVKTVGGGCCPCPCPPQPP------PPQPQPPAAAPQAGEDPTETSDALL 115
A + P P T P P P P P +P PAAA E+P + A+
Sbjct: 1095 AAAVPTPEEP---TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
Query: 116 VLEGLESEAESLETNSCSEEELSSP 140
E S A ++ T EE +SP
Sbjct: 1152 TPEESASAAVAVPT----PEESASP 1172
Score = 36.6 bits (83), Expect = 0.065
Identities = 52/201 (25%), Positives = 68/201 (33%), Gaps = 21/201 (10%)
Query: 10 PEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLA-----LERTWGPAAGLEAQLAALG 64
PEE A P P E P A+ A A LE PAA + A +
Sbjct: 1153 PEESASAAVAVPTPEESASPA--AAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
Query: 65 -LGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESE 123
L + P P +P PAAA E+PT ++ A+L E L S
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
Query: 124 AESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQ 183
A S+ T EE +SP L+ P VP P +P + E
Sbjct: 1271 AASVPT----PEEPASPAAAVSN-----LEEPASPAAAVPTPEVAAIPAASVPTPE---- 1317
Query: 184 QQQQPPPPPPPPGPLRPLAGP 204
P PP + P+ P
Sbjct: 1318 VPAIPAAAVPPMEEVSPIGVP 1338
>gi|4826908 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
[Homo sapiens]
Length = 728
Score = 52.4 bits (124), Expect = 1e-06
Identities = 61/202 (30%), Positives = 86/202 (42%), Gaps = 39/202 (19%)
Query: 331 LVAPMGSSLQSFPLPP--PPPPHAPDA------FPRIAPIR-----------AAESLHSQ 371
L A G L P PP PPP APD FP + + A +L +
Sbjct: 246 LGATFGPLLLRAPPPPSSPPPGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPPALPPK 305
Query: 372 PPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRD-SSDP 430
PP+ P + S SL++ E WYWG ++ E+ KL+ PDG+FLVRD SS
Sbjct: 306 PPKAKPAPTVLANGGS-PPSLQDAE---WYWGDISREEVNEKLRDTPDGTFLVRDASSKI 361
Query: 431 RYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYF 490
+ +L+ R G ++ H G + F C SVV+ I H ++
Sbjct: 362 QGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTF---C-SVVDLINH-YRHESLAQYNAK 416
Query: 491 LRSRVPGLPPTPVQLLYPVSRF 512
L +R LLYPVS++
Sbjct: 417 LDTR----------LLYPVSKY 428
Score = 37.4 bits (85), Expect = 0.038
Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Query: 396 EKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHH 446
E+ WY G +N AE L GK DG+FL+R+SS R + S G T H
Sbjct: 618 EERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQ-RGCYACSVVVDGDTKH 667
Score = 35.8 bits (81), Expect = 0.11
Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 26/131 (19%)
Query: 34 ALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPA-GPGVKTVGGGCCPCPCPPQPPPP 92
AL+P LP AL + L L + PA GP V+ +G P + PPP
Sbjct: 208 ALEPPTLPLHRALTLRF-----LLQHLGRVARRAPALGPAVRALGATFGPLLL--RAPPP 260
Query: 93 QPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLL 152
PP G +P+ ALLV + L+ E E+E++ P L
Sbjct: 261 PSSPPPGGAPDGSEPSPDFPALLVEKLLQEHLE--------EQEVAPPA----------L 302
Query: 153 QPPGPELPPVP 163
P P+ P P
Sbjct: 303 PPKPPKAKPAP 313
>gi|188536047 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c1 [Homo sapiens]
Length = 1105
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 25/142 (17%)
Query: 70 GPGVKTVGGGCCPCPCPPQPPPPQP-----QPPAAAPQAGEDPTETSDALLVLEGLESEA 124
GPG+ +G P P Q PPP P PP PQ G+ P S ++ G
Sbjct: 976 GPGLAPLGAAGHPGMMPHQQPPPYPLMHHQMPPPHPPQPGQIPGPGS----MMPGQHMPG 1031
Query: 125 ESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFP-LQDLVPLGRLSRGEQQQQ 183
+ T + + + G G P P +PP+P L VPL G
Sbjct: 1032 RMIPTVAAN---IHPSGSG----------PTPPGMPPMPGNILGPRVPL-TAPNGMYPPP 1077
Query: 184 QQQQPPPPPPPPG-PLRPLAGP 204
QQQPPPPPP G P P GP
Sbjct: 1078 PQQQPPPPPPADGVPPPPAPGP 1099
Score = 31.2 bits (69), Expect = 2.7
Identities = 20/48 (41%), Positives = 20/48 (41%), Gaps = 6/48 (12%)
Query: 66 GQPAGPGVK-TVGGGCCPCPCPPQPPPPQ-----PQPPAAAPQAGEDP 107
G GP V T G P P QPPPP P PPA P A P
Sbjct: 1058 GNILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPPPPAPGPPASAAP 1105
Score = 30.8 bits (68), Expect = 3.6
Identities = 25/77 (32%), Positives = 28/77 (36%), Gaps = 10/77 (12%)
Query: 285 GETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPL 344
G + V +I G + P PP PP P L P L AP G
Sbjct: 1031 GRMIPTVAANIHPSG-SGPTPPGMPPMPGNILG---------PRVPLTAPNGMYPPPPQQ 1080
Query: 345 PPPPPPHAPDAFPRIAP 361
PPPPP A P AP
Sbjct: 1081 QPPPPPPADGVPPPPAP 1097
Score = 30.0 bits (66), Expect = 6.1
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 7/80 (8%)
Query: 303 PHPPTPP--PPPRRSLSLLDDISGTLPT-SVLVAPMGSSLQSFPLPPPPPPHAPDAFPRI 359
PHPP P P P + +PT + + P GS P PP PP +
Sbjct: 1009 PHPPQPGQIPGPGSMMPGQHMPGRMIPTVAANIHPSGSG----PTPPGMPPMPGNILGPR 1064
Query: 360 APIRAAESLHSQPPQHLQCP 379
P+ A ++ PPQ P
Sbjct: 1065 VPLTAPNGMYPPPPQQQPPP 1084
Score = 30.0 bits (66), Expect = 6.1
Identities = 18/44 (40%), Positives = 19/44 (43%), Gaps = 4/44 (9%)
Query: 66 GQPAGPGVKTVGGGCCPCPCPP--QPPPPQPQPPAAAPQAGEDP 107
G P PG + G P P PPPPQ QPP P G P
Sbjct: 1052 GMPPMPG--NILGPRVPLTAPNGMYPPPPQQQPPPPPPADGVPP 1093
>gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo
sapiens]
Length = 316
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/246 (27%), Positives = 89/246 (36%), Gaps = 30/246 (12%)
Query: 4 RNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAAL 63
R VG P ++++ A G + P + G ++ GP A +A + L
Sbjct: 65 REVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAP-QALASLL 123
Query: 64 GLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAA----PQAGEDPTETSDALLVLEG 119
G G+ AG + GG P P + PAAA P G+ P TS A G
Sbjct: 124 GPGK-AGCRARLQGGSSGASP----RRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSG 178
Query: 120 LESEAESLETNSCSEEELSSPGRG---GGGGGRLLL-QPPGPELPPVPFPLQDLVPLGRL 175
+ PG G GRLL +PP +LPP P PL
Sbjct: 179 TVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPP-PLPLC-------- 229
Query: 176 SRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGK 235
+ + PPPPP PPGP P R + RL + C GG G G G
Sbjct: 230 -----RSRWVLAPPPPPAPPGPNAAAHPPLRPP--RARLQDPVDPERCPGGPSRGPGHGT 282
Query: 236 RPSGEL 241
EL
Sbjct: 283 HAHSEL 288
Score = 35.8 bits (81), Expect = 0.11
Identities = 49/196 (25%), Positives = 67/196 (34%), Gaps = 40/196 (20%)
Query: 192 PPPPGPLRP-----LAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAA 246
P PGP P L GP + G + RL GGS G + P G A+A
Sbjct: 108 PQSPGPCAPQALASLLGPGKAGC-RARLQ---------GGSSGASPR-RLPGGRGPAAAF 156
Query: 247 SLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPP 306
++ G R + + + T P S PL + PH P
Sbjct: 157 AVEPGTGQRPRNTSLAQASR-SGTVPGLPPASLQPL-----------RVPYFAPPGPHDP 204
Query: 307 TPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA---PIR 363
T P R ++ P+ L P+ + L PPPPP P P A P+R
Sbjct: 205 TSRGPGRL-------LTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPG--PNAAAHPPLR 255
Query: 364 AAESLHSQPPQHLQCP 379
+ P +CP
Sbjct: 256 PPRARLQDPVDPERCP 271
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/128 (32%), Positives = 55/128 (42%), Gaps = 16/128 (12%)
Query: 90 PPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGG--- 146
PPP+ PP P+ PT S L ++ L + + E N PGR GG
Sbjct: 685 PPPEGVPP---PELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAA 741
Query: 147 GG---RLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPP------PPPPGP 197
GG R+L++PP P P + L L R G Q ++ +PP P PP P P
Sbjct: 742 GGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGAEPPAPLTSRALPPEPAP 801
Query: 198 LRPLAGPS 205
L GPS
Sbjct: 802 AL-LGGPS 808
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 51.6 bits (122), Expect = 2e-06
Identities = 85/336 (25%), Positives = 120/336 (35%), Gaps = 60/336 (17%)
Query: 82 PCPCPPQPPP---PQPQPPAAAPQAGE-------DPTETSDALLVLEGLESEAESLETNS 131
P P PP PPP P P PP+A P + + DP S L ++ + + N
Sbjct: 8 PPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQIND 67
Query: 132 CSEEEL-SSPGRGGGGGGRLLLQPPGPELPPV-------PFPLQDLVPLGR--LSRGEQQ 181
S ++ SS G GGG + G PP FP+ L P G+ ++ G+
Sbjct: 68 RSAPQIESSKGTNKEGGGSANTR--GASTPPTLGDLFAGGFPV--LRPAGQRDVAGGKTG 123
Query: 182 QQQQQQPPPPPPP----PGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRP 237
Q + P P P GPL P A P RL T +G + P
Sbjct: 124 QGPGSRAPSPRLPNKTISGPLIPPASP-----------RLGNTSEAHGAARTAPPRPNVP 172
Query: 238 SGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSP-LFTGETVSLVDVDIS 296
+ + P L + +P+ P T + +V +
Sbjct: 173 APPPPTPPPPPPPL------------PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 297 QRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAF 356
P PP P PPP S+L D + V P + L P+PPP P P +
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKA--------VKPQLAPLHLPPIPPPLPLLPPCGY 272
Query: 357 PRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASL 392
P + A+ + +Q P PL S S ASL
Sbjct: 273 PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL 308
Score = 49.7 bits (117), Expect = 7e-06
Identities = 69/275 (25%), Positives = 90/275 (32%), Gaps = 67/275 (24%)
Query: 154 PPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIR 213
PP P LPP P PL PPPPPP P+ R+ K R
Sbjct: 6 PPPPPLPPPPPPLG-------------------APPPPPPSAPPVSTDTSSLRRADPKGR 46
Query: 214 LS---------RLFRTKSCN-----------------GGSGGGDGTGKRPS-GELAASA- 245
+ RL + N GGS G P+ G+L A
Sbjct: 47 SALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGF 106
Query: 246 -----ASLTDMGGSA-----GRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDI 295
A D+ G G + R P T + P S T E
Sbjct: 107 PVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
Query: 296 SQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSV-LVAPMGSSLQSF------PLPPPP 348
+ + +P PPTPPPPP L + + P LV+P G + P+P P
Sbjct: 167 PRPNVPAPPPPTPPPPPP---PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
Query: 349 PPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRP 383
PP P P P+ A L + + PL+ P
Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLP 258
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/203 (25%), Positives = 61/203 (30%), Gaps = 64/203 (31%)
Query: 10 PEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPA 69
P +V A P P P P LPP L ++ ++ L + P
Sbjct: 166 PPRPNVPAPPPPTPPP----------PPPPLPPPLP------SSSPIKTPLVS-----PP 204
Query: 70 GPGVK---TVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAES 126
GP K V PC PP PPPP P PP P + L L
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL--------- 255
Query: 127 LETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQ 186
LPP+P PL L P G + Q
Sbjct: 256 -------------------------------HLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Query: 187 QPPPPPPPPGPLRPLAGPSRKGS 209
PP PP PL P A S + S
Sbjct: 285 DAQEPPAPPPPLPPYASCSPRAS 307
Score = 36.6 bits (83), Expect = 0.065
Identities = 32/124 (25%), Positives = 45/124 (36%), Gaps = 16/124 (12%)
Query: 86 PPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGG 145
PP PPPP P + +P+A S L G+ S +E+ +P + G
Sbjct: 289 PPAPPPPLPPYASCSPRA-------SLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAG 341
Query: 146 GGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPS 205
P P PP P GR G + PPP PP P L+ S
Sbjct: 342 AQAL-----PAPPAPPGSQPFLQKKRHGRPGAG----GGKLNPPPAPPARSPTTELSSKS 392
Query: 206 RKGS 209
++ +
Sbjct: 393 QQAT 396
Score = 30.8 bits (68), Expect = 3.6
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 23/64 (35%)
Query: 303 PHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPI 362
P PP PPPP LP P+G+ PPPPPP AP + +
Sbjct: 2 PVPPPPPPP--------------LPPP--PPPLGA-------PPPPPPSAPPVSTDTSSL 38
Query: 363 RAAE 366
R A+
Sbjct: 39 RRAD 42
>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
Length = 651
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 16/146 (10%)
Query: 65 LGQPAGPGVKTVGGGCCPC----PCP-PQPPPPQPQPPAAAPQAGEDPTETSDAL-LVLE 118
LGQP G G GGG P P P PPP Q A AP+ +P + + AL L L+
Sbjct: 5 LGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRLALD 64
Query: 119 GLES----EAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGR 174
L + A + + + ++ G GG + P GPE P + P
Sbjct: 65 QLSALGLGGAGDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAP--- 121
Query: 175 LSRGEQQQQQQQQPPPPPPPPGPLRP 200
G PPPPPPP P P
Sbjct: 122 ---GSLPLLDPNASPPPPPPPRPSPP 144
Score = 47.4 bits (111), Expect = 4e-05
Identities = 65/270 (24%), Positives = 101/270 (37%), Gaps = 66/270 (24%)
Query: 130 NSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPP 189
+S + + G GGGGG + PGP P P + Q+ P
Sbjct: 3 SSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPP------------------EGAQEAAP 44
Query: 190 PPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLT 249
P PPP P + ++ L +L S G G GD + +G+ AA+A
Sbjct: 45 APRPPPEP------DDAAAALRLALDQL----SALGLGGAGDTDEEGAAGDGAAAA---- 90
Query: 250 DMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPP 309
GG+ G A +P A +P + +P ++ L+D + S P PP
Sbjct: 91 --GGADG---GAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNAS---------PPPP 136
Query: 310 PPPRRSLSLLDDISGTLPTSVLVAP----------MGSSLQSFPL----PPPPPPHAPDA 355
PPPR S D +G P + P +GS +S + P P H +
Sbjct: 137 PPPRPSPP--DVFAGFAPHPAALGPPTLLADQMSVIGSRKKSVNMTECVPVPSSEHVAEI 194
Query: 356 FPR----IAPIRAAESLHSQPPQHLQCPLY 381
R I +RA + + + P + P++
Sbjct: 195 VGRQGCKIKALRAKTNTYIKTPVRGEEPVF 224
Score = 36.2 bits (82), Expect = 0.085
Identities = 53/188 (28%), Positives = 61/188 (32%), Gaps = 74/188 (39%)
Query: 9 PPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLG-- 66
PP E EAAP P P D A LAL+ QL+ALGLG
Sbjct: 34 PPPEGAQEAAPAPRPPP--------EPDDAAAALRLALD-----------QLSALGLGGA 74
Query: 67 ------QPAGPGVKTVG---GGCCPCPCPPQ----------------------------- 88
AG G G GG P P PP
Sbjct: 75 GDTDEEGAAGDGAAAAGGADGGAAPEPVPPDGPEAGAPPTLAPAVAPGSLPLLDPNASPP 134
Query: 89 -PPPPQPQPP------AAAPQAGEDPTETSDALLVLEGLESEAESLETNSC-----SEEE 136
PPPP+P PP A P A PT +D + V + S +S+ C SE
Sbjct: 135 PPPPPRPSPPDVFAGFAPHPAALGPPTLLADQMSV---IGSRKKSVNMTECVPVPSSEHV 191
Query: 137 LSSPGRGG 144
GR G
Sbjct: 192 AEIVGRQG 199
>gi|166795247 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 24/149 (16%)
Query: 367 SLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRD 426
+L +PP+ P+ + S L+ WYWG ++ E+ KL+ PDG+FLVRD
Sbjct: 36 ALPPKPPK----PMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRD 91
Query: 427 SSDP-RYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFED--RCQSVVEFIKRAIMHSK 483
+S + +L+ R G ++ H G + F D SVVE I
Sbjct: 92 ASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYG------FSDPLTFNSVVELINH------ 139
Query: 484 NGKFLYFLRSRVPGLPPTPVQLLYPVSRF 512
Y S P V+L+YPVSR+
Sbjct: 140 -----YHHESLAQYNPKLDVKLMYPVSRY 163
Score = 33.5 bits (75), Expect = 0.55
Identities = 15/29 (51%), Positives = 20/29 (68%)
Query: 400 WYWGPMNWEDAEMKLKGKPDGSFLVRDSS 428
W+ +N AE L GKPDG+FL+R+SS
Sbjct: 358 WFVEDINRVQAEDLLYGKPDGAFLIRESS 386
>gi|166795245 phosphoinositide-3-kinase, regulatory subunit 3 (p55,
gamma) [Homo sapiens]
Length = 461
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 24/149 (16%)
Query: 367 SLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRD 426
+L +PP+ P+ + S L+ WYWG ++ E+ KL+ PDG+FLVRD
Sbjct: 36 ALPPKPPK----PMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRD 91
Query: 427 SSDP-RYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFED--RCQSVVEFIKRAIMHSK 483
+S + +L+ R G ++ H G + F D SVVE I
Sbjct: 92 ASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYG------FSDPLTFNSVVELINH------ 139
Query: 484 NGKFLYFLRSRVPGLPPTPVQLLYPVSRF 512
Y S P V+L+YPVSR+
Sbjct: 140 -----YHHESLAQYNPKLDVKLMYPVSRY 163
Score = 33.5 bits (75), Expect = 0.55
Identities = 15/29 (51%), Positives = 20/29 (68%)
Query: 400 WYWGPMNWEDAEMKLKGKPDGSFLVRDSS 428
W+ +N AE L GKPDG+FL+R+SS
Sbjct: 358 WFVEDINRVQAEDLLYGKPDGAFLIRESS 386
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.137 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,864,111
Number of Sequences: 37866
Number of extensions: 2542375
Number of successful extensions: 50224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 598
Number of HSP's successfully gapped in prelim test: 1287
Number of HSP's that attempted gapping in prelim test: 19950
Number of HSP's gapped (non-prelim): 18654
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.