Guide to the Human Genome
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Name: SOCS2 Sequence: fasta or formatted (198aa) NCBI GI: 4507263
Description:

suppressor of cytokine signaling-2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         12           2
 C cysteine            2.5          5           1
 D aspartate           4.0          8           1
 E glutamate           6.6         13           2
 F phenylalanine       2.0          4           1
 G glycine             8.1         16           2
 H histidine           2.0          4           1
 I isoleucine          4.0          8           2
 K lysine              7.6         15           1
 L leucine            11.6         23           2
 M methionine          1.5          3           1
 N asparagine          2.5          5           1
 P proline             5.6         11           1
 Q glutamine           4.0          8           1
 R arginine            5.6         11           1
 S serine              7.6         15           2
 T threonine           8.1         16           1
 V valine              4.0          8           2
 W tryptophan          2.0          4           1
 Y tyrosine            4.5          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   suppressor of cytokine signaling-2 
CISH                  0.348   cytokine-inducible SH2-containing protein isoform 1...
CISH                  0.348   cytokine-inducible SH2-containing protein isoform 2 ...
SOCS6                 0.187   suppressor of cytokine signaling 6 
SOCS3                 0.169   suppressor of cytokine signaling 3 
SOCS1                 0.164   suppressor of cytokine signaling 1 
SOCS7                 0.153   suppressor of cytokine signaling 7 
SOCS5                 0.132   suppressor of cytokine signaling 5 
SOCS5                 0.132   suppressor of cytokine signaling 5 
SOCS4                 0.122   suppressor of cytokine signaling 4 
SOCS4                 0.122   suppressor of cytokine signaling 4 
PIK3R3                0.088   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.088   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R1                0.086   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.086   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.086   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R2                0.075   phosphoinositide-3-kinase, regulatory subunit 2 (beta...
SHE                   0.060   Src homology 2 domain containing E 
LOC100291393          0.047   PREDICTED: hypothetical protein XP_002347924 
SHC2                  0.047   SHC (Src homology 2 domain containing) transforming...
NCK2                  0.044   NCK adaptor protein 2 isoform A 
NCK2                  0.044   NCK adaptor protein 2 isoform A 
SHC3                  0.044   src homology 2 domain-containing transforming prote...
DAPP1                 0.044   dual adaptor of phosphotyrosine and 3-phosphoinosit...
NCK1                  0.042   NCK adaptor protein 1 
SHB                   0.042   Src homology 2 domain containing adaptor protein B ...
CRK                   0.039   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CRK                   0.039   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
VAV2                  0.039   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV2                  0.039   vav 2 guanine nucleotide exchange factor isoform 2 [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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