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Search of human proteins with 53759103
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53759103 importin 8 [Homo sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53759103 importin 8 [Homo sapiens] 2077 0.0
gi|5453998 importin 7 [Homo sapiens] 1373 0.0
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 92 2e-18
gi|21361659 importin 9 [Homo sapiens] 58 5e-08
gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens] 49 2e-05
gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens] 49 2e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 42 0.003
gi|46276863 parathymosin [Homo sapiens] 42 0.004
gi|55956788 nucleolin [Homo sapiens] 40 0.011
gi|38788260 bromodomain PHD finger transcription factor isoform ... 40 0.011
gi|38788274 bromodomain PHD finger transcription factor isoform ... 40 0.011
gi|224831257 importin 13 [Homo sapiens] 40 0.015
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 40 0.015
gi|28274705 family with sequence similarity 9, member A [Homo sa... 39 0.025
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 39 0.025
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 39 0.025
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 39 0.033
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 38 0.057
gi|4505999 protein phosphatase 1G [Homo sapiens] 37 0.074
gi|29826282 protein phosphatase 1G [Homo sapiens] 37 0.074
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 37 0.074
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 37 0.097
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 37 0.097
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.097
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 37 0.13
>gi|53759103 importin 8 [Homo sapiens]
Length = 1037
Score = 2077 bits (5381), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYL 60
MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYL
Sbjct: 1 MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYL 60
Query: 61 KNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIK 120
KNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIK
Sbjct: 61 KNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIK 120
Query: 121 HDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLP 180
HDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLP
Sbjct: 121 HDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLP 180
Query: 181 RIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRT 240
RIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRT
Sbjct: 181 RIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRT 240
Query: 241 VPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVG 300
VPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVG
Sbjct: 241 VPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVG 300
Query: 301 IQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMC 360
IQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMC
Sbjct: 301 IQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMC 360
Query: 361 YKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQIL 420
YKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQIL
Sbjct: 361 YKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQIL 420
Query: 421 TDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWV 480
TDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWV
Sbjct: 421 TDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWV 480
Query: 481 LHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHV 540
LHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHV
Sbjct: 481 LHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHV 540
Query: 541 RPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEE 600
RPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEE
Sbjct: 541 RPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEE 600
Query: 601 VEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAY 660
VEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAY
Sbjct: 601 VEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAY 660
Query: 661 SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFT 720
SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFT
Sbjct: 661 SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFT 720
Query: 721 MCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRT 780
MCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRT
Sbjct: 721 MCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRT 780
Query: 781 MCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIG 840
MCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIG
Sbjct: 781 MCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIG 840
Query: 841 LSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEE 900
LSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEE
Sbjct: 841 LSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEE 900
Query: 901 ISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQF 960
ISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQF
Sbjct: 901 ISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQF 960
Query: 961 FTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFE 1020
FTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFE
Sbjct: 961 FTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFE 1020
Query: 1021 NKGVLSAFNFGTVPSNN 1037
NKGVLSAFNFGTVPSNN
Sbjct: 1021 NKGVLSAFNFGTVPSNN 1037
>gi|5453998 importin 7 [Homo sapiens]
Length = 1038
Score = 1373 bits (3554), Expect = 0.0
Identities = 668/1033 (64%), Positives = 822/1033 (79%), Gaps = 4/1033 (0%)
Query: 1 MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYL 60
MD N II+AL+GT+DP LR AAE +LN+++K +NF +LL+I +S+ ++ PVRQA IYL
Sbjct: 1 MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYL 60
Query: 61 KNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIK 120
KNM+TQYWPDRE PG+ I P+ I E DR IR+NIVE II SP+L+RVQLT C+ IIK
Sbjct: 61 KNMITQYWPDRETAPGD-ISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIK 119
Query: 121 HDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLP 180
HD+P W +VDKI +YLQS +SA WLG LLCLYQLVK YEYKK EER PL+ AMQ FLP
Sbjct: 120 HDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLP 179
Query: 181 RIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRT 240
++ + +QLL D S SVL+QKQI KIFYALVQY LPL+L+N Q +T W+EI +T+++R
Sbjct: 180 VLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRD 239
Query: 241 VPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVG 300
VP ETL ++EDDRPEL WWKCKKWALHI+ARLFERYGSPGNV+KEY EF+E FLK +AVG
Sbjct: 240 VPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVG 299
Query: 301 IQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMC 360
+QQVLLK+L QY++K+Y+APRVLQQ NY+NQGV H++TWK +KPHIQ I +DVIF +MC
Sbjct: 300 VQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMC 359
Query: 361 YKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQIL 420
Y D DEELWQEDPYEYIRMKFD+FED+ SPTTAAQTLL+TA KRKEVL K M FCYQIL
Sbjct: 360 YTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQIL 419
Query: 421 TDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWV 480
T+PN DPRKKDGALH+IGSLAEILLKK ++KDQME LQNHVFPL S LGY+RAR+CWV
Sbjct: 420 TEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWV 479
Query: 481 LHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHV 540
LH F +KF ++ NL+ A+EL ++ LI+D+EMPVKVEAA+ALQ LISNQ +AKEY+ P +
Sbjct: 480 LHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFI 539
Query: 541 RPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEE 600
RP+MQ LLHI+RETENDD+TNVIQKMICEYS+EV IAV+MTQHLA F +V+Q+ EE
Sbjct: 540 RPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEE 599
Query: 601 -VEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLA 659
+DK V AMGIL+TIDT+L+VVEDHKEITQQLE ICL++I VLQ+HV+EFYEEI SLA
Sbjct: 600 GSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLA 659
Query: 660 YSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILF 719
+SLTC +SPQMWQLL +++EVFQQD F+YFTDMMPLLHNYVT+DTDTLLS+ K+LE+++
Sbjct: 660 HSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIY 719
Query: 720 TMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELR 779
+MC+KVL G AGEDAECHAAKLLEVIILQCKGRGIDQCIPLFV+ LERLTR VKTSELR
Sbjct: 720 SMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELR 779
Query: 780 TMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCII 839
TMCLQVAIAALYYNP LLL+TLE ++ P+N P+T FI QW+ND DCFLG HDRKMC++
Sbjct: 780 TMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVL 839
Query: 840 GLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENE 899
GL L++++ P ++ V GQI+P+ + LF GLK+ A + E D +E E
Sbjct: 840 GLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETE 899
Query: 900 EISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPL-DLDNSVDEY 958
E+ SDE++ + Q + E+ +D+DW+E+ EETALEG+ST + D DN VDEY
Sbjct: 900 ELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEY 959
Query: 959 QFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFT 1018
Q F T+Q+R+ WYQ L L+E+QR LQ++ TLA+ RR E+ K IE+ GG+
Sbjct: 960 QIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHES-KMIEKHGGYK 1018
Query: 1019 FENKGVLSAFNFG 1031
F V S+FNFG
Sbjct: 1019 FSAPVVPSSFNFG 1031
>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
Length = 971
Score = 92.4 bits (228), Expect = 2e-18
Identities = 200/942 (21%), Positives = 388/942 (41%), Gaps = 144/942 (15%)
Query: 2 DLNRIIQALKGTIDPK--LRIAAENEL-----NQSYKIINFAPSLLRIIVSDHVEFPVRQ 54
+L + + LK T+DP +R AE L NQ+Y P LL ++ + ++
Sbjct: 7 NLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNY------PLLLLTLLEKSQDNVIKV 60
Query: 55 AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114
A++ KN + + W E P + I E DR I+ NIV ++ SP+ ++ QL+
Sbjct: 61 CASVTFKNYIKRNWRIVEDEPNK------ICEADRVAIKANIVHLMLSSPEQIQKQLSDA 114
Query: 115 LRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY--EYKKAE---ERE 169
+ I + DFP WP ++ ++ QS G L + L K Y E+K E E +
Sbjct: 115 ISIIGREDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIK 174
Query: 170 PLIIAMQIFLPRIQQQIVQLLP----DSSYYSVLLQKQIL--KIFYALVQYALPLQLVNN 223
++ A + L + + ++L D+S +L IL K+FY+L LP +N
Sbjct: 175 LVLDAFALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDN 234
Query: 224 QTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVT 283
M TWM F T++ T+ + L D+++ L+ + K + A L+
Sbjct: 235 --METWMNNFHTLL--TLDNKLLQTDDEEEAGLL--ELLKSQICDNAALY---------A 279
Query: 284 KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQM 343
++Y E + +L + I +L+ + + ++ L + +
Sbjct: 280 QKYDEEFQRYLPRFVTAIWNLLVTTGQEVK-------------YDLLVSNAIQFLASVCE 326
Query: 344 KPHIQNISED----------VIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTA 393
+PH +N+ ED VI M ++ DEE ++++ EYIR + D + A
Sbjct: 327 RPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLE-GSDIDTRRRA 385
Query: 394 AQTLLYTAAKKRKEVLPKMM-----AFCYQILTDPNFDPRKKDGALHVIGSLA-EILLKK 447
A L+ K + + + + + +P+ + + KD A++++ SLA + +K
Sbjct: 386 ACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQK 445
Query: 448 SLFKDQMEL-----FLQNHVFPLL----LSNLGYLRARSCWVLHAFSSLKFHNEL---NL 495
EL F NH+ P L ++ L+A + + F N++ +L
Sbjct: 446 HGITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYI-----MIFRNQVPKEHL 500
Query: 496 RNAVELAKKSLIEDKEMPVKVEAALALQSLIS--NQIQAKEYMKPHVRPIMQEL------ 547
++ L L + + + V AA AL+ L + A + + P ++ L
Sbjct: 501 LVSIPLLINHL-QAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFK 559
Query: 548 -LHIVRETENDDVT-------NVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYE 599
L + +EN+ + +++Q+ I Y + ++ +TQ L + K +
Sbjct: 560 ALTLPGSSENEYIMKAIMRSFSLLQEAIIPY---IPTLITQLTQKLLAV-SKNPSKPHFN 615
Query: 600 EVEDKTVMAMGILHTIDTILTVVEDHKE-----ITQQLENICLRIIDLVLQ--KHVIEFY 652
+ + + I T V + +E T+ L+N I V Q ++E +
Sbjct: 616 HYMFEAI-CLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETH 674
Query: 653 EEILSLAY-SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLS- 710
+ + +Y +L H + P +W+ G + ++ LL ++ ++T+ S
Sbjct: 675 KNDIPSSYMALFPHLLQPVLWERTGNI------------PALVRLLQAFLERGSNTIASA 722
Query: 711 NAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLT 770
A + L + +K++ A + + LL II +DQ L+ +RL
Sbjct: 723 AADKIPGLLGVFQKLIASKANDHQGFY---LLNSIIEHMPPESVDQYRKQIFILLFQRLQ 779
Query: 771 RGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLG 830
T +++ + + + + Y L + IQ P G + + I + + G
Sbjct: 780 NSKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQ-PKMFGMVLEKII---IPEIQKVSG 835
Query: 831 HHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGL 872
+ ++K+C +G++ L L PP +D ++ +L +GL
Sbjct: 836 NVEKKICAVGITKL--LTECPPMMDTEYTKLWTPLLQSLIGL 875
>gi|21361659 importin 9 [Homo sapiens]
Length = 1041
Score = 57.8 bits (138), Expect = 5e-08
Identities = 192/1086 (17%), Positives = 403/1086 (37%), Gaps = 168/1086 (15%)
Query: 6 IIQALKGTIDP--KLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNM 63
++ L G + P ++R AAE ++ F L + V +RQ A++ LK
Sbjct: 25 LVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQY 84
Query: 64 VTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDF 123
V +W + E P E + IR+ + G+ S VR + + AI D+
Sbjct: 85 VETHWCAQ----SEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDW 140
Query: 124 PGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQ 183
P WP + + + L S + G++ L + RE M + P I
Sbjct: 141 PEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFT----------REVTDTQMPLVAPVIL 190
Query: 184 QQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWM-----EIFRTIID 238
++ ++ + Y + + + ++IF ++ + + + +
Sbjct: 191 PEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQ 250
Query: 239 RTVPPETLHIDEDDRPEL---VWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLK 295
P+ D + E+ V K + H+V+ + + N E + F+++
Sbjct: 251 ALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLT---ESAAFYVR 307
Query: 296 TYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVI 355
T ++V + + ++ F +++ + +S + K ++ ++I
Sbjct: 308 TEVNYTEEVEDPVDSDGEVLGF--ENLVFSIFEFVHALLENS----KFKSTVKKALPELI 361
Query: 356 FSVMCYKDEDEE---LWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKM 412
+ ++ Y EE +W +P +++ + D Y A LL A + E +
Sbjct: 362 YYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAAL 421
Query: 413 MAFCYQILTDPNFDPRKKDGALH----------VIGSLAEIL---LKKSLFKDQMELFLQ 459
A + L + + K G H +GS+ I+ +K M FL
Sbjct: 422 AAAATRHLQEA--EQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLT 479
Query: 460 NHVF-PLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEA 518
N + L LS +L R+ W F ++ EL ++ ++ L E + V++ A
Sbjct: 480 NVILADLNLSVSPFLLGRALWAASRF-TVAMSPEL-IQQFLQATVSGLHETQPPSVRISA 537
Query: 519 ALALQSLISNQIQAKE---YMKPHVRPIMQELLHIVRETENDDVTNVIQKM--ICEYSQE 573
A+ +Q++ E ++P + I+ L+H+ + ++ + V++ + +C E
Sbjct: 538 VRAIWG-YCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPE 596
Query: 574 -VASIAVDMTQHLAEIFGKV--------LQSDEYEEVED----KTVMAMGILHTIDTILT 620
AS+ + IF K L D ++E+ + M M ++ T+ +I+
Sbjct: 597 FTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQ 656
Query: 621 VVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYE 680
D + +C ID++ + + P + QLL
Sbjct: 657 APAD-----KIPAGLCATAIDIL-----------------TTVVRNTKPPLSQLLICQAF 694
Query: 681 VFQQDCFEYFTDMMPL------LHNYVTIDTDTLL-----SNAKHLEILFTMCRKVLCGD 729
C + D + L YV++ + + L + + ++L
Sbjct: 695 PAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPR 754
Query: 730 AGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAA 789
E +L+ +I + GR + + + ++ +L ++ + S ++++ + V
Sbjct: 755 TSEFTAAFVGRLVSTLISKA-GRELGENLDQILRAILSKMQQAETLSVMQSL-IMVFAHL 812
Query: 790 LYYNPDLLLHTLERIQLPHNPGPITVQFI-NQWMNDTDCFLGHHDRKMCIIGLSILLE-- 846
++ + LL L LP G ++F+ +W + F G ++ K+ + L LL+
Sbjct: 813 VHTQLEPLLEFL--CSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHG 870
Query: 847 ------------------------LQNRPPAVD--------AVVGQIVPSILFLFLGLKQ 874
++ R + ++ +I+ I+ + +
Sbjct: 871 INADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVME 930
Query: 875 VCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQ---SNNGRGEDEEEEDDD 931
A RQ E S+ + DM E++E +EEE + Q + + + ED E+D++
Sbjct: 931 ANAARQATPAE-WSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEE 989
Query: 932 WDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALIT---VQSRDAAWYQLLMAPLSEDQR 988
D + L++ PL YQ QA +T Q Y + L++++R
Sbjct: 990 DDPDALKD--------PL--------YQIDLQAYLTDFLCQFAQQPCYIMFSGHLNDNER 1033
Query: 989 TALQEV 994
LQ +
Sbjct: 1034 RVLQTI 1039
>gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]
Length = 1015
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/170 (21%), Positives = 70/170 (41%), Gaps = 14/170 (8%)
Query: 1 MDLNR----IIQALKGTI--DPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQ 54
MDLN ++Q L D + AE +L Q F LL I + ++ VR
Sbjct: 41 MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRW 100
Query: 55 AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114
A +Y K+ + +YW + P + E ++ +R ++ + + Q+ +
Sbjct: 101 LAVLYFKHGIDRYW--------RRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVL 152
Query: 115 LRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKK 164
+ + + D P WP ++ + ++ Q +LL Y + KT K+
Sbjct: 153 IAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKR 202
Score = 40.8 bits (94), Expect = 0.007
Identities = 50/235 (21%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 345 PHIQNISEDVIFSVMCYKDEDEELWQEDP--YEYIRMKFDIFEDYASPTTAAQTLLYTAA 402
P + I ++ +E+ +W+EDP + D ++ P T + L
Sbjct: 400 PTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCT--EVLFIDIF 457
Query: 403 KKRKEVLPKMMAFCYQILTDP-NFDPRK----KDGALHVIGSLAEILLKKSLFKDQMELF 457
+ + L ++ Q L P N + KD + +G LA L S+ DQ +
Sbjct: 458 HEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVG-LAAYELFDSVDFDQ---W 513
Query: 458 LQNHVFP---LLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPV 514
+N + P ++ + LR R W++ + S+KF ++ LR + A +L++D+++ V
Sbjct: 514 FKNQLLPELQVIHNRYKPLRRRVIWLIGQWISVKFKSD--LRPMLYEAICNLLQDQDLVV 571
Query: 515 KVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRE-TENDDVTNVIQKMIC 568
++E A L+ + + + P++ + L ++++ TE D +V+ + C
Sbjct: 572 RIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSC 626
>gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]
Length = 975
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/170 (21%), Positives = 70/170 (41%), Gaps = 14/170 (8%)
Query: 1 MDLNR----IIQALKGTI--DPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQ 54
MDLN ++Q L D + AE +L Q F LL I + ++ VR
Sbjct: 1 MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRW 60
Query: 55 AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114
A +Y K+ + +YW + P + E ++ +R ++ + + Q+ +
Sbjct: 61 LAVLYFKHGIDRYW--------RRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVL 112
Query: 115 LRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKK 164
+ + + D P WP ++ + ++ Q +LL Y + KT K+
Sbjct: 113 IAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKR 162
Score = 40.8 bits (94), Expect = 0.007
Identities = 50/235 (21%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 345 PHIQNISEDVIFSVMCYKDEDEELWQEDP--YEYIRMKFDIFEDYASPTTAAQTLLYTAA 402
P + I ++ +E+ +W+EDP + D ++ P T + L
Sbjct: 360 PTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCT--EVLFIDIF 417
Query: 403 KKRKEVLPKMMAFCYQILTDP-NFDPRK----KDGALHVIGSLAEILLKKSLFKDQMELF 457
+ + L ++ Q L P N + KD + +G LA L S+ DQ +
Sbjct: 418 HEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVG-LAAYELFDSVDFDQ---W 473
Query: 458 LQNHVFP---LLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPV 514
+N + P ++ + LR R W++ + S+KF ++ LR + A +L++D+++ V
Sbjct: 474 FKNQLLPELQVIHNRYKPLRRRVIWLIGQWISVKFKSD--LRPMLYEAICNLLQDQDLVV 531
Query: 515 KVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRE-TENDDVTNVIQKMIC 568
++E A L+ + + + P++ + L ++++ TE D +V+ + C
Sbjct: 532 RIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSC 586
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 42.0 bits (97), Expect = 0.003
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 885 EDRSKAEKADMEENEE-----ISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEE 939
E+ + E+ D EE EE +EEE + + G E+EEEE+D+ +EE LEE
Sbjct: 900 EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959
Query: 940 TALEGFST 947
F T
Sbjct: 960 VEDLEFGT 967
Score = 37.0 bits (84), Expect = 0.097
Identities = 18/59 (30%), Positives = 32/59 (54%)
Query: 881 LVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEE 939
++N + E+ + EE EE +EEE + + E+EEEE+++++EE EE
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
>gi|46276863 parathymosin [Homo sapiens]
Length = 102
Score = 41.6 bits (96), Expect = 0.004
Identities = 22/74 (29%), Positives = 36/74 (48%)
Query: 870 LGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEED 929
L K + ++ V + K K ++ E EE ++EEE + + G EDEEEE+
Sbjct: 12 LSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEE 71
Query: 930 DDWDEEVLEETALE 943
+D + L+ A E
Sbjct: 72 EDDEGPALKRAAEE 85
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 40.0 bits (92), Expect = 0.011
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 11/71 (15%)
Query: 884 REDRSKAEKADMEENEEISSDEEETN-----------VTAQAMQSNNGRGEDEEEEDDDW 932
+ED + E D EE+EE DE+E A A + + ++++E+DDD
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
Query: 933 DEEVLEETALE 943
+E+ EE A+E
Sbjct: 202 EEDDSEEEAME 212
Score = 32.3 bits (72), Expect = 2.4
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 14/78 (17%)
Query: 872 LKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVT--------------AQAMQS 917
+K A + +D + D +++EE S+EE T A+ +
Sbjct: 175 MKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 918 NNGRGEDEEEEDDDWDEE 935
+ ED+E+EDDD DE+
Sbjct: 235 DEDEEEDDEDEDDDDDED 252
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 40.0 bits (92), Expect = 0.011
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 872 LKQVCATRQLVNREDRSKAEKADMEENEE-ISSDEEETNVTAQAMQSNNGRGEDEEEEDD 930
L + A R+ VN+ E + EE E+ +S +EEE + A+ Q + EDE EEDD
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 931 DWDEEVLEE 939
D D + EE
Sbjct: 171 D-DSDYPEE 178
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 40.0 bits (92), Expect = 0.011
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 872 LKQVCATRQLVNREDRSKAEKADMEENEE-ISSDEEETNVTAQAMQSNNGRGEDEEEEDD 930
L + A R+ VN+ E + EE E+ +S +EEE + A+ Q + EDE EEDD
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 931 DWDEEVLEE 939
D D + EE
Sbjct: 171 D-DSDYPEE 178
>gi|224831257 importin 13 [Homo sapiens]
Length = 963
Score = 39.7 bits (91), Expect = 0.015
Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 28/176 (15%)
Query: 55 AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114
A+A+++K +++YW D P + +E+ + Q+ I +V +L +
Sbjct: 79 ASALHIK--ISRYWSD---------IPTDQYESLKAQLFTQITR-FASGSKIVLTRLCVA 126
Query: 115 LRAIIKHDFPGHWP-GVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY----------EYK 163
L ++ P WP V D + + S G L L +L+ +Y+
Sbjct: 127 LASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYR 186
Query: 164 KAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQ 219
K R L + P ++Q LL S S + QK +LK F + VQ +PLQ
Sbjct: 187 KGLVRTSLAVECGAVFPLLEQ----LLQQPSSPSCVRQK-VLKCFSSWVQLEVPLQ 237
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 39.7 bits (91), Expect = 0.015
Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 7/80 (8%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDE-EEEDDDWDEEVL 937
+++ + ++ S+ E+ +E EE+ +EEE A+ ++ GE+E EEE+ + +EEVL
Sbjct: 292 QEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE----EGEEELEEEELEEEEEVL 347
Query: 938 EETALEG--FSTPLDLDNSV 955
EE G F PL++ S+
Sbjct: 348 EENEQRGEEFHLPLEMPLSI 367
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
Query: 885 EDRSKAEKADMEENEEISSDEEETN---VTAQAMQSNNGRGEDEEEEDDDWDEEVLEE 939
E++S A EE E+ + DEEE + A+ EDEEEE +D +EE +EE
Sbjct: 267 ENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEE 324
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 38.9 bits (89), Expect = 0.025
Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 832 HDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAE 891
H RK+ + + E Q A +A + A +++ ED + E
Sbjct: 170 HTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAA---AAAEAAAAAAEVIVVEDEEEEE 226
Query: 892 KADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGF 945
K + EE EE + EE + + G +E EE+++ +EE EE ++ F
Sbjct: 227 KEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAF 280
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 38.9 bits (89), Expect = 0.025
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
Query: 883 NREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEE 939
N E+ + + D+EE+EE+ D EE +G E+EEEE+++ +EE EE
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEV-----DEDGEEEEEEEEEEEEEEEEEEE 248
Score = 35.4 bits (80), Expect = 0.28
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 884 REDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALE 943
R RS + +EE SD E + + Q NN E+E E+D ++E +EE A E
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221
Query: 944 GFSTPLDLDNSVDE 957
D VDE
Sbjct: 222 --------DEEVDE 227
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.025
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
Query: 883 NREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEE 939
N E+ + + D+EE+EE+ D EE +G E+EEEE+++ +EE EE
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEV-----DEDGEEEEEEEEEEEEEEEEEEE 248
Score = 35.4 bits (80), Expect = 0.28
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 884 REDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALE 943
R RS + +EE SD E + + Q NN E+E E+D ++E +EE A E
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221
Query: 944 GFSTPLDLDNSVDE 957
D VDE
Sbjct: 222 --------DEEVDE 227
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 38.5 bits (88), Expect = 0.033
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 13/89 (14%)
Query: 880 QLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEV--- 936
++ E+ K E+ + EE EE+ EEE + + G +DEE+ED+D ++
Sbjct: 380 EMKKEEEMKKKEEKEEEEEEEMKQKEEEEEI--RNKNEEEGESKDEEDEDEDGGQKPEGE 437
Query: 937 ------LEETALEGFSTPLD--LDNSVDE 957
EET E PLD D+ +DE
Sbjct: 438 PQQDPGTEETYGEVEEEPLDEAQDDDLDE 466
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 37.7 bits (86), Expect = 0.057
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 8/84 (9%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEG 944
++ + E+ D EE EEI ++E+ + + ++ E+EEEE+++ +EE E+ +
Sbjct: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE---EEEEEEEEEEEEEENEDHQMNC 175
Query: 945 FSTPL-----DLDNSVDEYQFFTQ 963
+T + DN+ DEY + +
Sbjct: 176 HNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 31.2 bits (69), Expect = 5.3
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 884 REDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALE 943
+ D S ++ D + E ++EE + +N DE+EED++ D E EE E
Sbjct: 81 KADSSSVDECDDSDGTEDMDEKEEDE--GEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE 138
Query: 944 GFSTPLDLDNSVDE 957
D ++ DE
Sbjct: 139 DEDDDEDGEDVEDE 152
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 37.4 bits (85), Expect = 0.074
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 859 GQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSN 918
G+ PS L +V ++ + ED S + + E++EE S EEE +++ ++
Sbjct: 235 GEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECS--EEEDGYSSEEAENE 292
Query: 919 NGRGEDEE-EEDDDWDEEVLEETALEGFSTP 948
+ EE EEDD+ +EE + +EG P
Sbjct: 293 EDEDDTEEAEEDDEEEEEEMMVPGMEGKEEP 323
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 37.4 bits (85), Expect = 0.074
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 859 GQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSN 918
G+ PS L +V ++ + ED S + + E++EE S EEE +++ ++
Sbjct: 235 GEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECS--EEEDGYSSEEAENE 292
Query: 919 NGRGEDEE-EEDDDWDEEVLEETALEGFSTP 948
+ EE EEDD+ +EE + +EG P
Sbjct: 293 EDEDDTEEAEEDDEEEEEEMMVPGMEGKEEP 323
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 37.4 bits (85), Expect = 0.074
Identities = 19/72 (26%), Positives = 37/72 (51%)
Query: 883 NREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETAL 942
+ + E+ D EE+EE D+E + +++ ++ E EEEDDD ++ ++
Sbjct: 604 SEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDT 663
Query: 943 EGFSTPLDLDNS 954
EG T + L+ +
Sbjct: 664 EGEKTSMKLNKT 675
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 262 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 321
Query: 939 ETALE 943
++A E
Sbjct: 322 QSAEE 326
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 244 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 290 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 272 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 331
Query: 939 ETALE 943
++A E
Sbjct: 332 QSAEE 336
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 254 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 300 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 263 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 322
Query: 939 ETALE 943
++A E
Sbjct: 323 QSAEE 327
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 245 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 291 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 272 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 331
Query: 939 ETALE 943
++A E
Sbjct: 332 QSAEE 336
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 254 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 300 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 240 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 299
Query: 939 ETALE 943
++A E
Sbjct: 300 QSAEE 304
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 222 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 268
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 268 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 229 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 288
Query: 939 ETALE 943
++A E
Sbjct: 289 QSAEE 293
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 211 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 257
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 257 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 18 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 77
Query: 939 ETALE 943
++A E
Sbjct: 78 QSAEE 82
Score = 33.1 bits (74), Expect = 1.4
Identities = 14/45 (31%), Positives = 28/45 (62%)
Query: 891 EKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 46
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 46 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 95
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 37.0 bits (84), Expect = 0.097
Identities = 21/65 (32%), Positives = 31/65 (47%)
Query: 879 RQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLE 938
R+ + E S + EE EE +EEE T++ + E+EEEE EE E
Sbjct: 274 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 333
Query: 939 ETALE 943
++A E
Sbjct: 334 QSAEE 338
Score = 34.7 bits (78), Expect = 0.48
Identities = 15/47 (31%), Positives = 29/47 (61%)
Query: 889 KAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
K E+ D+ + + SD E +A++ + +G G +EEEE+++ +EE
Sbjct: 256 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 302
Score = 30.4 bits (67), Expect = 9.0
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 885 EDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEE 935
E+ S +E+++ EE EE +EEET ++ + EEE +D + E
Sbjct: 302 EEGSTSEESEEEEEEE-EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
a [Homo sapiens]
Length = 1216
Score = 36.6 bits (83), Expect = 0.13
Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 510 KEMPVKVEAALALQSLISNQIQAKEYMK-PHVRPIMQELLHIVRETENDDVTNVIQKMIC 568
K + +K + L +L Q +++Y K H++ ++Q+L + E +N+ + + K IC
Sbjct: 1004 KLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKL--KEIC 1061
Query: 569 EYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILT-------- 620
E +E + M + E + D+ + E+KT M + + +
Sbjct: 1062 E--KEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSK 1119
Query: 621 ----VVEDHKEITQQL 632
+VE HKEI QQ+
Sbjct: 1120 RQEKLVEKHKEIRQQI 1135
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,094,200
Number of Sequences: 37866
Number of extensions: 1700059
Number of successful extensions: 11449
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 8409
Number of HSP's gapped (non-prelim): 1832
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.