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Search of human proteins with 53729339
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53729339 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
(727 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53729339 mitochondrial translational initiation factor 2 prec... 1449 0.0
gi|53729337 mitochondrial translational initiation factor 2 prec... 1449 0.0
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 107 3e-23
gi|157426893 GUF1 GTPase homolog [Homo sapiens] 84 4e-16
gi|54607086 eukaryotic elongation factor, selenocysteine-tRNA-sp... 72 2e-12
gi|34147630 Tu translation elongation factor, mitochondrial prec... 65 2e-10
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform... 58 4e-08
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1... 58 4e-08
gi|217272894 elongation factor Tu GTP binding domain containing ... 55 2e-07
gi|217272892 elongation factor Tu GTP binding domain containing ... 55 2e-07
gi|94966754 elongation factor Tu GTP binding domain containing 1... 54 7e-07
gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens] 53 1e-06
gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens] 52 1e-06
gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens] 52 1e-06
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens] 52 1e-06
gi|46094014 peptide chain release factor 3 [Homo sapiens] 49 1e-05
gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo s... 49 1e-05
gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo s... 49 1e-05
gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo s... 49 1e-05
gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [H... 49 2e-05
gi|4503483 eukaryotic translation elongation factor 2 [Homo sapi... 48 3e-05
gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [H... 47 6e-05
gi|239757543 PREDICTED: similar to eukaryotic translation elonga... 46 1e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 42 0.003
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 42 0.003
gi|94966752 elongation factor Tu GTP binding domain containing 1... 41 0.004
gi|239756373 PREDICTED: similar to elongation factor Tu GTP bind... 40 0.006
gi|239750897 PREDICTED: similar to elongation factor Tu GTP bind... 40 0.006
gi|239745282 PREDICTED: similar to elongation factor Tu GTP bind... 40 0.006
gi|38045919 huntingtin interacting protein 1 [Homo sapiens] 40 0.010
>gi|53729339 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 1449 bits (3752), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG
Sbjct: 1 MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
Query: 61 AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT
Sbjct: 61 AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
Query: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS
Sbjct: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
Query: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA
Sbjct: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
Query: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV
Sbjct: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
Query: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI
Sbjct: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
Query: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG
Sbjct: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
Query: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK
Sbjct: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
Query: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA
Sbjct: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
Query: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY
Sbjct: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
Query: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK
Sbjct: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
Query: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK
Sbjct: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
Query: 721 TSWDPGF 727
TSWDPGF
Sbjct: 721 TSWDPGF 727
>gi|53729337 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
Length = 727
Score = 1449 bits (3752), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG
Sbjct: 1 MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
Query: 61 AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT
Sbjct: 61 AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
Query: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS
Sbjct: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
Query: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA
Sbjct: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
Query: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV
Sbjct: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
Query: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI
Sbjct: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
Query: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG
Sbjct: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
Query: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK
Sbjct: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
Query: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA
Sbjct: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
Query: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY
Sbjct: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
Query: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK
Sbjct: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
Query: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK
Sbjct: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
Query: 721 TSWDPGF 727
TSWDPGF
Sbjct: 721 TSWDPGF 727
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 107 bits (268), Expect = 3e-23
Identities = 145/590 (24%), Positives = 231/590 (39%), Gaps = 128/590 (21%)
Query: 179 RSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKIT------- 231
R+P++ ++GHVD GKT +LDK R T V E GGITQ IGA V L + + T
Sbjct: 630 RAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFD 689
Query: 232 ----------FLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
+DTPGH +FS +R RG+ + DI +LVV G+ QT+ESI K +
Sbjct: 690 RENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKC 749
Query: 282 PIILAVNKCDK-----------AEADPEKVKK------ELLAYDVVCE------------ 312
P I+A+NK D+ A +K KK E A ++ E
Sbjct: 750 PFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFY 809
Query: 313 ---DYGGDVQAVPVSALTGDNLMALAEATVALAE-MLELKADPNGPVEGTVIESFTDKGR 368
D V VP SA TGD + +L V L + ML + + V+E G
Sbjct: 810 ENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGM 869
Query: 369 GLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAG 428
G I+ G L++G ++ G+ G
Sbjct: 870 GTTIDVILINGRLKEGDTIIV--------------------------PGVEG-----PIV 898
Query: 429 EEILEVESEPRAREVVDWRKYEQEQE-KGQEDLKII-EEKRKEHKEAHQKAREKYGHLLW 486
+I + P +E+ +YE+ +E + + +KI+ ++ K K +
Sbjct: 899 TQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPV 958
Query: 487 KKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECEL 546
K ++ L++ +K +EK V ++ GS+EA+L + T E+
Sbjct: 959 LKDELIHELKQTLN-AIKLEEK--------GVYVQASTLGSLEALLEFLKT------SEV 1003
Query: 547 ELVHFGVGDVSANDVNLAETF------DGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
+G V DV A VI F+V Q+ A GV+I +IIY
Sbjct: 1004 PYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIY 1063
Query: 601 RLVE-----------DLQEELS--SRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCR 647
L + QEE + PC ++ P + V G
Sbjct: 1064 HLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILP----------QYIFNSRDPIVMGVT 1113
Query: 648 VQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLD 697
V+ GQ+ KQ + + + G +TS++ + + + K G + + ++
Sbjct: 1114 VEAGQV-KQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIE 1162
>gi|157426893 GUF1 GTPase homolog [Homo sapiens]
Length = 669
Score = 84.3 bits (207), Expect = 4e-16
Identities = 60/225 (26%), Positives = 104/225 (46%), Gaps = 27/225 (12%)
Query: 184 TIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKI------------- 230
+I+ HVDHGK+TL D+ + +T Q + V G +
Sbjct: 72 SIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEG 131
Query: 231 -----TFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIIL 285
+DTPGH FS +R V+LVV A++G+ QTV + A +AQ+ +I
Sbjct: 132 KQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIP 191
Query: 286 AVNKCDKAEADPEKVKKEL-LAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEM 344
+NK D ADPE+V+ ++ +D+ + + + +SA G N+ ++ +A + +
Sbjct: 192 VINKIDLKNADPERVENQIEKVFDIPSD------ECIKISAKLGTNVESVLQAII--ERI 243
Query: 345 LELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVA 389
K P+ V +S D+ RG++ + G + KG +V+
Sbjct: 244 PPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVS 288
>gi|54607086 eukaryotic elongation factor,
selenocysteine-tRNA-specific [Homo sapiens]
Length = 596
Score = 72.0 bits (175), Expect = 2e-12
Identities = 67/246 (27%), Positives = 107/246 (43%), Gaps = 46/246 (18%)
Query: 183 VTIMGHVDHGKTTLLDKFRKTQVAAV-------ETGGITQHIG--AFLVSLPS------- 226
V ++GH+D GKT L T A GIT +G F V LP+
Sbjct: 10 VGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPLPARLRSSLP 69
Query: 227 ------------GE---KITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
GE ++T +D PGHA+ GAQ+ D+++LV+ G+ Q+ E
Sbjct: 70 EFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAE 129
Query: 272 SIQHAKDAQVPIILAVNKCD-----KAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSAL 326
+ + A +++ +NK D K +A +K+ K++ + G + +PV+A
Sbjct: 130 CLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPI--IPVAAK 187
Query: 327 TGDNLMALAEATVALAEMLEL--------KADPNGPVEGTVIESFTDKGRGLVTTAIIQR 378
G EA + E++EL DP+GP +V F+ KG+G V T I
Sbjct: 188 PGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILS 247
Query: 379 GTLRKG 384
G++ G
Sbjct: 248 GSISLG 253
>gi|34147630 Tu translation elongation factor, mitochondrial
precursor [Homo sapiens]
Length = 455
Score = 65.5 bits (158), Expect = 2e-10
Identities = 70/232 (30%), Positives = 98/232 (42%), Gaps = 34/232 (14%)
Query: 183 VTIMGHVDHGKTTLLD------------KFRKTQ----VAAVETGGITQHIGAFLVSLPS 226
V +GHVDHGKTTL KF+K + GIT + A + +
Sbjct: 63 VGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITIN-AAHVEYSTA 121
Query: 227 GEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP-IIL 285
D PGHA + G D +LVVAA+DG M QT E + A+ V +++
Sbjct: 122 ARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQIGVEHVVV 181
Query: 286 AVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMAL----AEATVAL 341
VNK D A D E V+ L + ++G + PV + G L AL E +
Sbjct: 182 YVNKAD-AVQDSEMVELVELEIRELLTEFGYKGEETPV--IVGSALCALEGRDPELGLKS 238
Query: 342 AEMLELKADPNGPVEGTVIES---------FTDKGRGLVTTAIIQRGTLRKG 384
+ L D PV +E ++ GRG V T ++RG L+KG
Sbjct: 239 VQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKG 290
>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
[Homo sapiens]
Length = 642
Score = 57.8 bits (138), Expect = 4e-08
Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)
Query: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
+ ++GHVD GK+TL+ K K A ETG
Sbjct: 221 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 280
Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
G+T +G + + IT +D PGH F GA D+ VLVV A G + E
Sbjct: 281 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 339
Query: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
+ ++ + +AVNK D+ E+ ++ + G DV
Sbjct: 340 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 399
Query: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
+P S L+G+NL+ ++++ + L E ++ P + P V + F D+G
Sbjct: 400 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 459
Query: 369 GLVTTAIIQRGTLRKGSVLVA 389
G T I+ G ++ G L+A
Sbjct: 460 GFCITGKIEAGYIQTGDRLLA 480
>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
[Homo sapiens]
Length = 684
Score = 57.8 bits (138), Expect = 4e-08
Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)
Query: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
+ ++GHVD GK+TL+ K K A ETG
Sbjct: 263 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 322
Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
G+T +G + + IT +D PGH F GA D+ VLVV A G + E
Sbjct: 323 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 381
Query: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
+ ++ + +AVNK D+ E+ ++ + G DV
Sbjct: 382 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 441
Query: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
+P S L+G+NL+ ++++ + L E ++ P + P V + F D+G
Sbjct: 442 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 501
Query: 369 GLVTTAIIQRGTLRKGSVLVA 389
G T I+ G ++ G L+A
Sbjct: 502 GFCITGKIEAGYIQTGDRLLA 522
>gi|217272894 elongation factor Tu GTP binding domain containing 2
isoform b [Homo sapiens]
Length = 937
Score = 55.1 bits (131), Expect = 2e-07
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 21/131 (16%)
Query: 183 VTIMGHVDHGKTTLLD--------KFRKT---QVAAVETGGITQHIGAFLVSLP------ 225
VT+ GH+ HGKT +D + RK + + Q G + S P
Sbjct: 97 VTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLP 156
Query: 226 --SGEKITF--LDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
G+ F +DTPGH FS G +++D VVL + A +GVM T I+HA ++
Sbjct: 157 DTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERL 216
Query: 282 PIILAVNKCDK 292
+ + +NK D+
Sbjct: 217 AVTVCINKIDR 227
>gi|217272892 elongation factor Tu GTP binding domain containing 2
isoform a [Homo sapiens]
Length = 972
Score = 55.1 bits (131), Expect = 2e-07
Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 21/131 (16%)
Query: 183 VTIMGHVDHGKTTLLD--------KFRKT---QVAAVETGGITQHIGAFLVSLP------ 225
VT+ GH+ HGKT +D + RK + + Q G + S P
Sbjct: 132 VTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLP 191
Query: 226 --SGEKITF--LDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
G+ F +DTPGH FS G +++D VVL + A +GVM T I+HA ++
Sbjct: 192 DTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERL 251
Query: 282 PIILAVNKCDK 292
+ + +NK D+
Sbjct: 252 AVTVCINKIDR 262
>gi|94966754 elongation factor Tu GTP binding domain containing 1
isoform 1 [Homo sapiens]
Length = 1120
Score = 53.5 bits (127), Expect = 7e-07
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 19/129 (14%)
Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
+ ++ HVDHGKTTL D K R E GIT A + +
Sbjct: 22 ICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 81
Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPI 283
G + I +D+PGH FS+ + ++ D ++VV A +GV QT ++ A +
Sbjct: 82 GNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRP 141
Query: 284 ILAVNKCDK 292
+L +NK D+
Sbjct: 142 VLVINKIDR 150
>gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
Length = 751
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 20/142 (14%)
Query: 183 VTIMGHVDHGKTTLLDK--FRKTQVAAVETGGITQHIGAFLVSLPSGEK----------- 229
+ I H+D GKTTL ++ + ++A + +GA + S+ +
Sbjct: 49 IGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATY 108
Query: 230 -------ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP 282
I +DTPGH F+ R +V D VLV+ A GV QT+ + K VP
Sbjct: 109 TMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVP 168
Query: 283 IILAVNKCDKAEADPEKVKKEL 304
+ +NK D+ ++P + +++
Sbjct: 169 FLTFINKLDRMGSNPARALQQM 190
>gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]
Length = 499
Score = 52.4 bits (124), Expect = 1e-06
Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)
Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
+++++ K K V P A P+ V ++ GHVD GK+T+ L
Sbjct: 53 EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 106
Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
+K+ + A++T G T +G + T LD PGH +F
Sbjct: 107 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 165
Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
GA D+ VLV++A G + QT E AK A V +I+ +NK D
Sbjct: 166 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 225
Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
+ E+ K++L+ + V + D+ +P S LTG NL ++ + L +
Sbjct: 226 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 285
Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
L PN GP+ +++ + D G V ++ G++ KG LV
Sbjct: 286 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 333
>gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]
Length = 636
Score = 52.4 bits (124), Expect = 1e-06
Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)
Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
+++++ K K V P A P+ V ++ GHVD GK+T+ L
Sbjct: 190 EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 243
Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
+K+ + A++T G T +G + T LD PGH +F
Sbjct: 244 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 302
Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
GA D+ VLV++A G + QT E AK A V +I+ +NK D
Sbjct: 303 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 362
Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
+ E+ K++L+ + V + D+ +P S LTG NL ++ + L +
Sbjct: 363 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 422
Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
L PN GP+ +++ + D G V ++ G++ KG LV
Sbjct: 423 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 470
>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
Length = 637
Score = 52.4 bits (124), Expect = 1e-06
Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)
Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
+++++ K K V P A P+ V ++ GHVD GK+T+ L
Sbjct: 191 EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 244
Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
+K+ + A++T G T +G + T LD PGH +F
Sbjct: 245 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 303
Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
GA D+ VLV++A G + QT E AK A V +I+ +NK D
Sbjct: 304 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 363
Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
+ E+ K++L+ + V + D+ +P S LTG NL ++ + L +
Sbjct: 364 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 423
Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
L PN GP+ +++ + D G V ++ G++ KG LV
Sbjct: 424 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 471
>gi|46094014 peptide chain release factor 3 [Homo sapiens]
Length = 628
Score = 49.3 bits (116), Expect = 1e-05
Identities = 71/288 (24%), Positives = 117/288 (40%), Gaps = 61/288 (21%)
Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTL---------------LDK 199
+++++RK+K + P P V +GHVD GK+T+ L+K
Sbjct: 182 EKEEIRKSKSVIV-PSGAPK---KEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEK 237
Query: 200 FRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAFSA 243
+ + A++T G T +G + T LD PGH +F
Sbjct: 238 YEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETER-KHFTILDAPGHKSFVP 296
Query: 244 MRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKAEA 295
GA D+ VLV++A G + QT E AK A V +I+ +NK D
Sbjct: 297 NMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTV 356
Query: 296 D-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEMLE 346
+ E+ K++L+ + V D+ +P S LTG N+ ++ L +
Sbjct: 357 NWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPY 416
Query: 347 LKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
L PN GP+ +++ + D G V ++ G++ KG LV
Sbjct: 417 LDNLPNFNRSIDGPIRLPIVDKYKD--MGTVVLGKLESGSIFKGQQLV 462
>gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo
sapiens]
Length = 732
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)
Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
+ IM H+D GKTT ++ + V+ G GIT A
Sbjct: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132
Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
G ++ +DTPGH F+ R +V D V V A GV QT+ + A +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191
Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
+NK DK E+ EK+K + L DVV ++
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251
Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
G D + P+ + L L E T A ++E AD + V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301
>gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo
sapiens]
Length = 513
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)
Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
+ IM H+D GKTT ++ + V+ G GIT A
Sbjct: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132
Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
G ++ +DTPGH F+ R +V D V V A GV QT+ + A +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191
Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
+NK DK E+ EK+K + L DVV ++
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251
Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
G D + P+ + L L E T A ++E AD + V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301
>gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo
sapiens]
Length = 779
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)
Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
+ IM H+D GKTT ++ + V+ G GIT A
Sbjct: 73 IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132
Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
G ++ +DTPGH F+ R +V D V V A GV QT+ + A +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191
Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
+NK DK E+ EK+K + L DVV ++
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251
Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
G D + P+ + L L E T A ++E AD + V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301
>gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [Homo
sapiens]
Length = 463
Score = 48.5 bits (114), Expect = 2e-05
Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 66/270 (24%)
Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
+ ++GHVD GK+T ++KF K ++ A
Sbjct: 10 IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69
Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
GIT I + IT +D PGH F G D VL+VAA G + +
Sbjct: 70 GITIDISLWKFETTK-YYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAE-ADPEK----VKKELLAYDVVCEDYGGDV 318
++ +HA A +I+ VNK D E A EK + KE+ AY V
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATV 188
Query: 319 QAVPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVIE 361
VP+S GDN++ + + V+L E L+ P P + +
Sbjct: 189 PFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRL 248
Query: 362 SFTD----KGRGLVTTAIIQRGTLRKGSVL 387
D G G V ++ G LR G V+
Sbjct: 249 PLQDVYKIGGIGTVPVGRVETGILRPGMVV 278
>gi|4503483 eukaryotic translation elongation factor 2 [Homo
sapiens]
Length = 858
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 46/192 (23%)
Query: 183 VTIMGHVDHGKTTLLDKFR-KTQVAAVETGGITQH-------------IGAFLVSL---- 224
++++ HVDHGK+TL D K + A G T+ I + +SL
Sbjct: 22 MSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYEL 81
Query: 225 -------------PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
+G I +D+PGH FS+ +VTD ++VV GV QT
Sbjct: 82 SENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141
Query: 272 SIQHAKDAQVPIILAVNKCDKA----EADPEKV----KKELLAYDVVCEDYG-------G 316
++ A ++ +L +NK D+A + +PE++ ++ + +V+ YG G
Sbjct: 142 VLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMG 201
Query: 317 DVQAVPVSALTG 328
++ PV G
Sbjct: 202 NIMIDPVLGTVG 213
>gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [Homo
sapiens]
Length = 462
Score = 47.0 bits (110), Expect = 6e-05
Identities = 71/302 (23%), Positives = 110/302 (36%), Gaps = 69/302 (22%)
Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
+ ++GHVD GK+T ++KF K ++ A
Sbjct: 10 IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69
Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
GIT I + S +T +D PGH F G D VL+VAA G + +
Sbjct: 70 GITIDISLWKFET-SKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAEAD-----PEKVKKELLAYDVVCEDYGGDV 318
++ +HA A +I+ VNK D E E++ KE+ Y + Y D
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTY-IKKIGYNPDT 187
Query: 319 QA-VPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVI 360
A VP+S GDN++ + + L E L+ P P + +
Sbjct: 188 VAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLR 247
Query: 361 ESFTD----KGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDE-NGKTIDEAYPSMP 415
D G G V ++ G L+ G V+ + E + + + EA P
Sbjct: 248 LPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDN 307
Query: 416 VG 417
VG
Sbjct: 308 VG 309
>gi|239757543 PREDICTED: similar to eukaryotic translation
elongation factor 1 alpha 2 [Homo sapiens]
Length = 444
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/266 (24%), Positives = 97/266 (36%), Gaps = 64/266 (24%)
Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
+ ++GHVD GK+T ++KF K ++ A
Sbjct: 10 IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69
Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
GIT I + IT +D PGH F G D VL+VAA G + +
Sbjct: 70 GITIDISLWKFETTK-YYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128
Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAE-ADPEK----VKKELLAYDVVCEDYGGDV 318
++ +HA A +I+ VNK D E A EK + KE+ AY V
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATV 188
Query: 319 QAVPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVIE 361
VP+S GDN++ + + L + + P+GP +
Sbjct: 189 PFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGXRLCPRISCPSIPSGPTFPS--H 246
Query: 362 SFTDKGRGLVTTAIIQRGTLRKGSVL 387
G G V ++ G LR G V+
Sbjct: 247 PLPSAGIGTVPVGRVETGILRPGMVV 272
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 41.6 bits (96), Expect = 0.003
Identities = 63/258 (24%), Positives = 120/258 (46%), Gaps = 57/258 (22%)
Query: 431 ILEVESEPRAREVVDW-------RKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGH 483
I++ + E + R+ +W R+ E+E K E+ + I+E+RK+ KE +K REK
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 484 LLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHE 543
+K++I++ + +EQ+ K K D++ +II + S Y+ H
Sbjct: 366 ---EKKNIVK--QEREQLISKEKIILREDAS-QQLIISSALKKS---------GYNNKH- 409
Query: 544 CELELVHFGVGDVSAN--DVNLAETFDGVIYGFNVN--AGNVIQQSAAKKGVKIKLHKII 599
LE + GD++ N D N + D +++ + NV +Q+ K+ +++K
Sbjct: 410 LSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVK----- 464
Query: 600 YRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKF 659
L+E +SS+ +ILA F + E K +A R + +++++K+
Sbjct: 465 ------LKESISSQ-------------TILADFKMEE--KNENLAKKRCSEELVKQERKY 503
Query: 660 KLTRN----GHVIWKGSL 673
+ T N G+ KG+L
Sbjct: 504 ENTDNKTELGNSDLKGNL 521
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 41.6 bits (96), Expect = 0.003
Identities = 63/258 (24%), Positives = 120/258 (46%), Gaps = 57/258 (22%)
Query: 431 ILEVESEPRAREVVDW-------RKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGH 483
I++ + E + R+ +W R+ E+E K E+ + I+E+RK+ KE +K REK
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 484 LLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHE 543
+K++I++ + +EQ+ K K D++ +II + S Y+ H
Sbjct: 366 ---EKKNIVK--QEREQLISKEKIILREDAS-QQLIISSALKKS---------GYNNKH- 409
Query: 544 CELELVHFGVGDVSAN--DVNLAETFDGVIYGFNVN--AGNVIQQSAAKKGVKIKLHKII 599
LE + GD++ N D N + D +++ + NV +Q+ K+ +++K
Sbjct: 410 LSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVK----- 464
Query: 600 YRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKF 659
L+E +SS+ +ILA F + E K +A R + +++++K+
Sbjct: 465 ------LKESISSQ-------------TILADFKMEE--KNENLAKKRCSEELVKQERKY 503
Query: 660 KLTRN----GHVIWKGSL 673
+ T N G+ KG+L
Sbjct: 504 ENTDNKTELGNSDLKGNL 521
>gi|94966752 elongation factor Tu GTP binding domain containing 1
isoform 2 [Homo sapiens]
Length = 1069
Score = 40.8 bits (94), Expect = 0.004
Identities = 20/63 (31%), Positives = 35/63 (55%)
Query: 230 ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNK 289
I +D+PGH FS+ + ++ D ++VV A +GV QT ++ A + +L +NK
Sbjct: 37 INLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINK 96
Query: 290 CDK 292
D+
Sbjct: 97 IDR 99
>gi|239756373 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 40.4 bits (93), Expect = 0.006
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
+ ++ HVD GKTTL D K R E GIT A + +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212
Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
G + I +D+PGH FS+ + ++ D ++VV A +GV Q E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260
>gi|239750897 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 40.4 bits (93), Expect = 0.006
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
+ ++ HVD GKTTL D K R E GIT A + +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212
Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
G + I +D+PGH FS+ + ++ D ++VV A +GV Q E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260
>gi|239745282 PREDICTED: similar to elongation factor Tu GTP binding
domain containing 1 [Homo sapiens]
Length = 263
Score = 40.4 bits (93), Expect = 0.006
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)
Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
+ ++ HVD GKTTL D K R E GIT A + +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212
Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
G + I +D+PGH FS+ + ++ D ++VV A +GV Q E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260
>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
Length = 1037
Score = 39.7 bits (91), Expect = 0.010
Identities = 30/136 (22%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Query: 442 EVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILR-------- 493
E+ + R+ ++ EK Q L IE K + +++ + K +EKY L+ +LR
Sbjct: 436 ELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQ 495
Query: 494 -FLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVE-AILNIIDTYDASHECELELVHF 551
+ R+ Q+ L+ +EK+E + ++ + +G + +L + A+ + EL+++
Sbjct: 496 VSMARQAQVDLE-REKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQG 554
Query: 552 GVGDVSANDVNLAETF 567
+ + ++ N A F
Sbjct: 555 SLETSAQSEANWAAEF 570
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,575,462
Number of Sequences: 37866
Number of extensions: 1160445
Number of successful extensions: 6510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 5545
Number of HSP's gapped (non-prelim): 791
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.