Guide to the Human Genome
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Search of human proteins with 53729337

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53729337 mitochondrial translational initiation factor 2
precursor [Homo sapiens]
         (727 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53729339 mitochondrial translational initiation factor 2 prec...  1449   0.0  
gi|53729337 mitochondrial translational initiation factor 2 prec...  1449   0.0  
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...   107   3e-23
gi|157426893 GUF1 GTPase homolog [Homo sapiens]                        84   4e-16
gi|54607086 eukaryotic elongation factor, selenocysteine-tRNA-sp...    72   2e-12
gi|34147630 Tu translation elongation factor, mitochondrial prec...    65   2e-10
gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform...    58   4e-08
gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1...    58   4e-08
gi|217272894 elongation factor Tu GTP binding domain containing ...    55   2e-07
gi|217272892 elongation factor Tu GTP binding domain containing ...    55   2e-07
gi|94966754 elongation factor Tu GTP binding domain containing 1...    54   7e-07
gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]        53   1e-06
gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]       52   1e-06
gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]       52   1e-06
gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]       52   1e-06
gi|46094014 peptide chain release factor 3 [Homo sapiens]              49   1e-05
gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo s...    49   1e-05
gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo s...    49   1e-05
gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo s...    49   1e-05
gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [H...    49   2e-05
gi|4503483 eukaryotic translation elongation factor 2 [Homo sapi...    48   3e-05
gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [H...    47   6e-05
gi|239757543 PREDICTED: similar to eukaryotic translation elonga...    46   1e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    42   0.003
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    42   0.003
gi|94966752 elongation factor Tu GTP binding domain containing 1...    41   0.004
gi|239756373 PREDICTED: similar to elongation factor Tu GTP bind...    40   0.006
gi|239750897 PREDICTED: similar to elongation factor Tu GTP bind...    40   0.006
gi|239745282 PREDICTED: similar to elongation factor Tu GTP bind...    40   0.006
gi|38045919 huntingtin interacting protein 1 [Homo sapiens]            40   0.010

>gi|53729339 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 1449 bits (3752), Expect = 0.0
 Identities = 727/727 (100%), Positives = 727/727 (100%)

Query: 1   MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
           MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG
Sbjct: 1   MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60

Query: 61  AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
           AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT
Sbjct: 61  AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120

Query: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
           DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS
Sbjct: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180

Query: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
           PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA
Sbjct: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240

Query: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
           FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV
Sbjct: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300

Query: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
           KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI
Sbjct: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360

Query: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
           ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG
Sbjct: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420

Query: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
           WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK
Sbjct: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480

Query: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
           YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA
Sbjct: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540

Query: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
           SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY
Sbjct: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600

Query: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
           RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK
Sbjct: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660

Query: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
           LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK
Sbjct: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720

Query: 721 TSWDPGF 727
           TSWDPGF
Sbjct: 721 TSWDPGF 727


>gi|53729337 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 1449 bits (3752), Expect = 0.0
 Identities = 727/727 (100%), Positives = 727/727 (100%)

Query: 1   MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60
           MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG
Sbjct: 1   MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTG 60

Query: 61  AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120
           AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT
Sbjct: 61  AALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNT 120

Query: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180
           DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS
Sbjct: 121 DIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRS 180

Query: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240
           PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA
Sbjct: 181 PVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAA 240

Query: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300
           FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV
Sbjct: 241 FSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKV 300

Query: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360
           KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI
Sbjct: 301 KKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVI 360

Query: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420
           ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG
Sbjct: 361 ESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITG 420

Query: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480
           WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK
Sbjct: 421 WRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREK 480

Query: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540
           YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA
Sbjct: 481 YGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDA 540

Query: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
           SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY
Sbjct: 541 SHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600

Query: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660
           RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK
Sbjct: 601 RLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFK 660

Query: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720
           LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK
Sbjct: 661 LTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAK 720

Query: 721 TSWDPGF 727
           TSWDPGF
Sbjct: 721 TSWDPGF 727


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score =  107 bits (268), Expect = 3e-23
 Identities = 145/590 (24%), Positives = 231/590 (39%), Gaps = 128/590 (21%)

Query: 179  RSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKIT------- 231
            R+P++ ++GHVD GKT +LDK R T V   E GGITQ IGA  V L +  + T       
Sbjct: 630  RAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFD 689

Query: 232  ----------FLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
                       +DTPGH +FS +R RG+ + DI +LVV    G+  QT+ESI   K  + 
Sbjct: 690  RENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKC 749

Query: 282  PIILAVNKCDK-----------AEADPEKVKK------ELLAYDVVCE------------ 312
            P I+A+NK D+             A  +K KK      E  A  ++ E            
Sbjct: 750  PFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFY 809

Query: 313  ---DYGGDVQAVPVSALTGDNLMALAEATVALAE-MLELKADPNGPVEGTVIESFTDKGR 368
               D    V  VP SA TGD + +L    V L + ML  +      +   V+E     G 
Sbjct: 810  ENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGM 869

Query: 369  GLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAG 428
            G     I+  G L++G  ++                            G+ G        
Sbjct: 870  GTTIDVILINGRLKEGDTIIV--------------------------PGVEG-----PIV 898

Query: 429  EEILEVESEPRAREVVDWRKYEQEQE-KGQEDLKII-EEKRKEHKEAHQKAREKYGHLLW 486
             +I  +   P  +E+    +YE+ +E +  + +KI+ ++  K           K   +  
Sbjct: 899  TQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPV 958

Query: 487  KKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECEL 546
             K  ++  L++     +K +EK         V ++    GS+EA+L  + T       E+
Sbjct: 959  LKDELIHELKQTLN-AIKLEEK--------GVYVQASTLGSLEALLEFLKT------SEV 1003

Query: 547  ELVHFGVGDVSANDVNLAETF------DGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIY 600
                  +G V   DV  A           VI  F+V      Q+ A   GV+I   +IIY
Sbjct: 1004 PYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIY 1063

Query: 601  RLVE-----------DLQEELS--SRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCR 647
             L +             QEE    +  PC ++  P                +   V G  
Sbjct: 1064 HLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILP----------QYIFNSRDPIVMGVT 1113

Query: 648  VQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLD 697
            V+ GQ+ KQ       + + +  G +TS++ +   + + K G +  + ++
Sbjct: 1114 VEAGQV-KQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIE 1162


>gi|157426893 GUF1 GTPase homolog [Homo sapiens]
          Length = 669

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 60/225 (26%), Positives = 104/225 (46%), Gaps = 27/225 (12%)

Query: 184 TIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKI------------- 230
           +I+ HVDHGK+TL D+  +      +T    Q +    V    G  +             
Sbjct: 72  SIVAHVDHGKSTLADRLLELTGTIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNCEG 131

Query: 231 -----TFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIIL 285
                  +DTPGH  FS   +R       V+LVV A++G+  QTV +   A +AQ+ +I 
Sbjct: 132 KQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSVIP 191

Query: 286 AVNKCDKAEADPEKVKKEL-LAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEM 344
            +NK D   ADPE+V+ ++   +D+  +      + + +SA  G N+ ++ +A +    +
Sbjct: 192 VINKIDLKNADPERVENQIEKVFDIPSD------ECIKISAKLGTNVESVLQAII--ERI 243

Query: 345 LELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVA 389
              K     P+   V +S  D+ RG++    +  G + KG  +V+
Sbjct: 244 PPPKVHRKNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVS 288


>gi|54607086 eukaryotic elongation factor,
           selenocysteine-tRNA-specific [Homo sapiens]
          Length = 596

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 67/246 (27%), Positives = 107/246 (43%), Gaps = 46/246 (18%)

Query: 183 VTIMGHVDHGKTTLLDKFRKTQVAAV-------ETGGITQHIG--AFLVSLPS------- 226
           V ++GH+D GKT L      T   A           GIT  +G   F V LP+       
Sbjct: 10  VGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGFSCFSVPLPARLRSSLP 69

Query: 227 ------------GE---KITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
                       GE   ++T +D PGHA+       GAQ+ D+++LV+    G+  Q+ E
Sbjct: 70  EFQAAPEAEPEPGEPLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAE 129

Query: 272 SIQHAKDAQVPIILAVNKCD-----KAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSAL 326
            +   + A   +++ +NK D     K +A  +K+ K++       +  G  +  +PV+A 
Sbjct: 130 CLVIGQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPI--IPVAAK 187

Query: 327 TGDNLMALAEATVALAEMLEL--------KADPNGPVEGTVIESFTDKGRGLVTTAIIQR 378
            G       EA   + E++EL          DP+GP   +V   F+ KG+G V T  I  
Sbjct: 188 PGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFSIKGQGTVMTGTILS 247

Query: 379 GTLRKG 384
           G++  G
Sbjct: 248 GSISLG 253


>gi|34147630 Tu translation elongation factor, mitochondrial
           precursor [Homo sapiens]
          Length = 455

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 70/232 (30%), Positives = 98/232 (42%), Gaps = 34/232 (14%)

Query: 183 VTIMGHVDHGKTTLLD------------KFRKTQ----VAAVETGGITQHIGAFLVSLPS 226
           V  +GHVDHGKTTL              KF+K +           GIT +  A +    +
Sbjct: 63  VGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERARGITIN-AAHVEYSTA 121

Query: 227 GEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP-IIL 285
                  D PGHA +      G    D  +LVVAA+DG M QT E +  A+   V  +++
Sbjct: 122 ARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLLARQIGVEHVVV 181

Query: 286 AVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMAL----AEATVAL 341
            VNK D A  D E V+   L    +  ++G   +  PV  + G  L AL     E  +  
Sbjct: 182 YVNKAD-AVQDSEMVELVELEIRELLTEFGYKGEETPV--IVGSALCALEGRDPELGLKS 238

Query: 342 AEMLELKADPNGPVEGTVIES---------FTDKGRGLVTTAIIQRGTLRKG 384
            + L    D   PV    +E          ++  GRG V T  ++RG L+KG
Sbjct: 239 VQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKG 290


>gi|223555963 Hsp70 subfamily B suppressor 1-like protein isoform 2
           [Homo sapiens]
          Length = 642

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)

Query: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
           + ++GHVD GK+TL+                       K  K   A      ETG     
Sbjct: 221 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 280

Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
           G+T  +G       + + IT +D PGH  F      GA   D+ VLVV A  G  +   E
Sbjct: 281 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 339

Query: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
           +    ++            + +AVNK D+     E+ ++         +  G    DV  
Sbjct: 340 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 399

Query: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
           +P S L+G+NL+  ++++        + L E ++    P    + P    V + F D+G 
Sbjct: 400 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 459

Query: 369 GLVTTAIIQRGTLRKGSVLVA 389
           G   T  I+ G ++ G  L+A
Sbjct: 460 GFCITGKIEAGYIQTGDRLLA 480


>gi|5729864 Hsp70 subfamily B suppressor 1-like protein isoform 1
           [Homo sapiens]
          Length = 684

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 64/261 (24%), Positives = 104/261 (39%), Gaps = 55/261 (21%)

Query: 183 VTIMGHVDHGKTTLLD----------------------KFRKTQVAAV----ETG----- 211
           + ++GHVD GK+TL+                       K  K   A      ETG     
Sbjct: 263 LVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERER 322

Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
           G+T  +G       + + IT +D PGH  F      GA   D+ VLVV A  G  +   E
Sbjct: 323 GVTMDVGMTKFETTT-KVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFE 381

Query: 272 SIQHAKD--------AQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYG---GDVQA 320
           +    ++            + +AVNK D+     E+ ++         +  G    DV  
Sbjct: 382 TGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGF 441

Query: 321 VPVSALTGDNLMALAEAT--------VALAEMLELKADP----NGPVEGTVIESFTDKGR 368
           +P S L+G+NL+  ++++        + L E ++    P    + P    V + F D+G 
Sbjct: 442 IPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGS 501

Query: 369 GLVTTAIIQRGTLRKGSVLVA 389
           G   T  I+ G ++ G  L+A
Sbjct: 502 GFCITGKIEAGYIQTGDRLLA 522


>gi|217272894 elongation factor Tu GTP binding domain containing 2
           isoform b [Homo sapiens]
          Length = 937

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 21/131 (16%)

Query: 183 VTIMGHVDHGKTTLLD--------KFRKT---QVAAVETGGITQHIGAFLVSLP------ 225
           VT+ GH+ HGKT  +D        + RK     +   +     Q  G  + S P      
Sbjct: 97  VTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLP 156

Query: 226 --SGEKITF--LDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
              G+   F  +DTPGH  FS     G +++D VVL + A +GVM  T   I+HA   ++
Sbjct: 157 DTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERL 216

Query: 282 PIILAVNKCDK 292
            + + +NK D+
Sbjct: 217 AVTVCINKIDR 227


>gi|217272892 elongation factor Tu GTP binding domain containing 2
           isoform a [Homo sapiens]
          Length = 972

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 21/131 (16%)

Query: 183 VTIMGHVDHGKTTLLD--------KFRKT---QVAAVETGGITQHIGAFLVSLP------ 225
           VT+ GH+ HGKT  +D        + RK     +   +     Q  G  + S P      
Sbjct: 132 VTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLP 191

Query: 226 --SGEKITF--LDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQV 281
              G+   F  +DTPGH  FS     G +++D VVL + A +GVM  T   I+HA   ++
Sbjct: 192 DTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERL 251

Query: 282 PIILAVNKCDK 292
            + + +NK D+
Sbjct: 252 AVTVCINKIDR 262


>gi|94966754 elongation factor Tu GTP binding domain containing 1
           isoform 1 [Homo sapiens]
          Length = 1120

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 19/129 (14%)

Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
           + ++ HVDHGKTTL D               K R       E   GIT    A  +   +
Sbjct: 22  ICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 81

Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPI 283
           G +   I  +D+PGH  FS+  +   ++ D  ++VV A +GV  QT   ++ A    +  
Sbjct: 82  GNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRP 141

Query: 284 ILAVNKCDK 292
           +L +NK D+
Sbjct: 142 VLVINKIDR 150


>gi|18390331 G elongation factor, mitochondrial 1 [Homo sapiens]
          Length = 751

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 20/142 (14%)

Query: 183 VTIMGHVDHGKTTLLDK--FRKTQVAAVETGGITQHIGAFLVSLPSGEK----------- 229
           + I  H+D GKTTL ++  +   ++A +        +GA + S+    +           
Sbjct: 49  IGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATY 108

Query: 230 -------ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVP 282
                  I  +DTPGH  F+    R  +V D  VLV+ A  GV  QT+   +  K   VP
Sbjct: 109 TMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVP 168

Query: 283 IILAVNKCDKAEADPEKVKKEL 304
            +  +NK D+  ++P +  +++
Sbjct: 169 FLTFINKLDRMGSNPARALQQM 190


>gi|194018522 G1 to S phase transition 1 isoform 3 [Homo sapiens]
          Length = 499

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)

Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
           +++++ K K  V  P A      P+   V ++  GHVD GK+T+               L
Sbjct: 53  EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 106

Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
           +K+ +              A++T       G T  +G         +  T LD PGH +F
Sbjct: 107 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 165

Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
                 GA   D+ VLV++A  G  +       QT E    AK A V  +I+ +NK D  
Sbjct: 166 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 225

Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
             +      E+ K++L+ +   V  +   D+  +P S LTG NL   ++     + L  +
Sbjct: 226 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 285

Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
             L   PN      GP+   +++ + D   G V    ++ G++ KG  LV
Sbjct: 286 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 333


>gi|194097354 G1 to S phase transition 1 isoform 2 [Homo sapiens]
          Length = 636

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)

Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
           +++++ K K  V  P A      P+   V ++  GHVD GK+T+               L
Sbjct: 190 EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 243

Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
           +K+ +              A++T       G T  +G         +  T LD PGH +F
Sbjct: 244 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 302

Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
                 GA   D+ VLV++A  G  +       QT E    AK A V  +I+ +NK D  
Sbjct: 303 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 362

Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
             +      E+ K++L+ +   V  +   D+  +P S LTG NL   ++     + L  +
Sbjct: 363 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 422

Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
             L   PN      GP+   +++ + D   G V    ++ G++ KG  LV
Sbjct: 423 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 470


>gi|194018520 G1 to S phase transition 1 isoform 1 [Homo sapiens]
          Length = 637

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 73/290 (25%), Positives = 120/290 (41%), Gaps = 65/290 (22%)

Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIM--GHVDHGKTTL---------------L 197
           +++++ K K  V  P A      P+   V ++  GHVD GK+T+               L
Sbjct: 191 EEEEIPKPKSVVAPPGA------PKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 244

Query: 198 DKFRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAF 241
           +K+ +              A++T       G T  +G         +  T LD PGH +F
Sbjct: 245 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEK-KHFTILDAPGHKSF 303

Query: 242 SAMRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKA 293
                 GA   D+ VLV++A  G  +       QT E    AK A V  +I+ +NK D  
Sbjct: 304 VPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDP 363

Query: 294 EAD-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEM 344
             +      E+ K++L+ +   V  +   D+  +P S LTG NL   ++     + L  +
Sbjct: 364 TVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFI 423

Query: 345 LELKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
             L   PN      GP+   +++ + D   G V    ++ G++ KG  LV
Sbjct: 424 PYLDNLPNFNRSVDGPIRLPIVDKYKD--MGTVVLGKLESGSICKGQQLV 471


>gi|46094014 peptide chain release factor 3 [Homo sapiens]
          Length = 628

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 71/288 (24%), Positives = 117/288 (40%), Gaps = 61/288 (21%)

Query: 155 KQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTL---------------LDK 199
           +++++RK+K  +  P   P         V  +GHVD GK+T+               L+K
Sbjct: 182 EKEEIRKSKSVIV-PSGAPK---KEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEK 237

Query: 200 FRKTQVA----------AVETG------GITQHIGAFLVSLPSGEKITFLDTPGHAAFSA 243
           + +              A++T       G T  +G         +  T LD PGH +F  
Sbjct: 238 YEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETER-KHFTILDAPGHKSFVP 296

Query: 244 MRARGAQVTDIVVLVVAADDGVMK-------QTVESIQHAKDAQVP-IILAVNKCDKAEA 295
               GA   D+ VLV++A  G  +       QT E    AK A V  +I+ +NK D    
Sbjct: 297 NMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTV 356

Query: 296 D-----PEKVKKELLAY-DVVCEDYGGDVQAVPVSALTGDNLMALAEAT---VALAEMLE 346
           +      E+ K++L+ +   V      D+  +P S LTG N+   ++       L  +  
Sbjct: 357 NWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPY 416

Query: 347 LKADPN------GPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLV 388
           L   PN      GP+   +++ + D   G V    ++ G++ KG  LV
Sbjct: 417 LDNLPNFNRSIDGPIRLPIVDKYKD--MGTVVLGKLESGSIFKGQQLV 462


>gi|25306287 mitochondrial elongation factor G2 isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)

Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
           + IM H+D GKTT  ++          +  V+ G             GIT    A     
Sbjct: 73  IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132

Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
             G ++  +DTPGH  F+    R  +V D  V V  A  GV  QT+   + A    +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191

Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
             +NK DK         E+  EK+K + L                DVV ++         
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251

Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
            G D +  P+  +    L  L E T A   ++E  AD +      V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301


>gi|25306283 mitochondrial elongation factor G2 isoform 3 [Homo
           sapiens]
          Length = 513

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)

Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
           + IM H+D GKTT  ++          +  V+ G             GIT    A     
Sbjct: 73  IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132

Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
             G ++  +DTPGH  F+    R  +V D  V V  A  GV  QT+   + A    +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191

Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
             +NK DK         E+  EK+K + L                DVV ++         
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251

Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
            G D +  P+  +    L  L E T A   ++E  AD +      V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301


>gi|19923640 mitochondrial elongation factor G2 isoform 1 [Homo
           sapiens]
          Length = 779

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 52/232 (22%)

Query: 183 VTIMGHVDHGKTTLLDKFR-----KTQVAAVETG-------------GITQHIGAFLVSL 224
           + IM H+D GKTT  ++          +  V+ G             GIT    A     
Sbjct: 73  IGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTFDW 132

Query: 225 PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPII 284
             G ++  +DTPGH  F+    R  +V D  V V  A  GV  QT+   + A    +P I
Sbjct: 133 -KGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHNIPRI 191

Query: 285 LAVNKCDK--------AEADPEKVKKELL--------------AYDVVCEDY-------- 314
             +NK DK         E+  EK+K + L                DVV ++         
Sbjct: 192 CFLNKMDKTGASFKYAVESIREKLKAKPLLLQLPIGEAKTFKGVVDVVMKEKLLWNCNSN 251

Query: 315 -GGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTD 365
            G D +  P+  +    L  L E T A   ++E  AD +      V+E F++
Sbjct: 252 DGKDFERKPLLEMNDPEL--LKETTEARNALIEQVADLDDEFADLVLEEFSE 301


>gi|4503475 eukaryotic translation elongation factor 1 alpha 2 [Homo
           sapiens]
          Length = 463

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 68/270 (25%), Positives = 100/270 (37%), Gaps = 66/270 (24%)

Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
           + ++GHVD GK+T                ++KF K                 ++ A    
Sbjct: 10  IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69

Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
           GIT  I  +         IT +D PGH  F      G    D  VL+VAA  G  +  + 
Sbjct: 70  GITIDISLWKFETTK-YYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128

Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAE-ADPEK----VKKELLAYDVVCEDYGGDV 318
              ++ +HA  A       +I+ VNK D  E A  EK    + KE+ AY          V
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATV 188

Query: 319 QAVPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVIE 361
             VP+S   GDN++  +                  + V+L E L+    P  P +  +  
Sbjct: 189 PFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRL 248

Query: 362 SFTD----KGRGLVTTAIIQRGTLRKGSVL 387
              D     G G V    ++ G LR G V+
Sbjct: 249 PLQDVYKIGGIGTVPVGRVETGILRPGMVV 278


>gi|4503483 eukaryotic translation elongation factor 2 [Homo
           sapiens]
          Length = 858

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 48/192 (25%), Positives = 82/192 (42%), Gaps = 46/192 (23%)

Query: 183 VTIMGHVDHGKTTLLDKFR-KTQVAAVETGGITQH-------------IGAFLVSL---- 224
           ++++ HVDHGK+TL D    K  + A    G T+              I +  +SL    
Sbjct: 22  MSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYEL 81

Query: 225 -------------PSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
                         +G  I  +D+PGH  FS+      +VTD  ++VV    GV  QT  
Sbjct: 82  SENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTET 141

Query: 272 SIQHAKDAQVPIILAVNKCDKA----EADPEKV----KKELLAYDVVCEDYG-------G 316
            ++ A   ++  +L +NK D+A    + +PE++    ++ +   +V+   YG       G
Sbjct: 142 VLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMG 201

Query: 317 DVQAVPVSALTG 328
           ++   PV    G
Sbjct: 202 NIMIDPVLGTVG 213


>gi|4503471 eukaryotic translation elongation factor 1 alpha 1 [Homo
           sapiens]
          Length = 462

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 71/302 (23%), Positives = 110/302 (36%), Gaps = 69/302 (22%)

Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
           + ++GHVD GK+T                ++KF K                 ++ A    
Sbjct: 10  IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69

Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
           GIT  I  +     S   +T +D PGH  F      G    D  VL+VAA  G  +  + 
Sbjct: 70  GITIDISLWKFET-SKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128

Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAEAD-----PEKVKKELLAYDVVCEDYGGDV 318
              ++ +HA  A       +I+ VNK D  E        E++ KE+  Y +    Y  D 
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTY-IKKIGYNPDT 187

Query: 319 QA-VPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVI 360
            A VP+S   GDN++  +                  +   L E L+    P  P +  + 
Sbjct: 188 VAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLR 247

Query: 361 ESFTD----KGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDE-NGKTIDEAYPSMP 415
               D     G G V    ++ G L+ G V+          +   E + + + EA P   
Sbjct: 248 LPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDN 307

Query: 416 VG 417
           VG
Sbjct: 308 VG 309


>gi|239757543 PREDICTED: similar to eukaryotic translation
           elongation factor 1 alpha 2 [Homo sapiens]
          Length = 444

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 65/266 (24%), Positives = 97/266 (36%), Gaps = 64/266 (24%)

Query: 183 VTIMGHVDHGKTTL---------------LDKFRKT----------------QVAAVETG 211
           + ++GHVD GK+T                ++KF K                 ++ A    
Sbjct: 10  IVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERER 69

Query: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTV- 270
           GIT  I  +         IT +D PGH  F      G    D  VL+VAA  G  +  + 
Sbjct: 70  GITIDISLWKFETTK-YYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGIS 128

Query: 271 ---ESIQHAKDAQV----PIILAVNKCDKAE-ADPEK----VKKELLAYDVVCEDYGGDV 318
              ++ +HA  A       +I+ VNK D  E A  EK    + KE+ AY          V
Sbjct: 129 KNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATV 188

Query: 319 QAVPVSALTGDNLMALA-----------------EATVALAEMLELKADPNGPVEGTVIE 361
             VP+S   GDN++  +                  +   L   +   + P+GP   +   
Sbjct: 189 PFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGXRLCPRISCPSIPSGPTFPS--H 246

Query: 362 SFTDKGRGLVTTAIIQRGTLRKGSVL 387
                G G V    ++ G LR G V+
Sbjct: 247 PLPSAGIGTVPVGRVETGILRPGMVV 272


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
           1 [Homo sapiens]
          Length = 1722

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/258 (24%), Positives = 120/258 (46%), Gaps = 57/258 (22%)

Query: 431 ILEVESEPRAREVVDW-------RKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGH 483
           I++ + E + R+  +W       R+ E+E  K  E+ + I+E+RK+ KE  +K REK   
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365

Query: 484 LLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHE 543
              +K++I++  + +EQ+  K K     D++   +II   +  S          Y+  H 
Sbjct: 366 ---EKKNIVK--QEREQLISKEKIILREDAS-QQLIISSALKKS---------GYNNKH- 409

Query: 544 CELELVHFGVGDVSAN--DVNLAETFDGVIYGFNVN--AGNVIQQSAAKKGVKIKLHKII 599
             LE +    GD++ N  D N  +  D +++    +    NV +Q+  K+ +++K     
Sbjct: 410 LSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVK----- 464

Query: 600 YRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKF 659
                 L+E +SS+             +ILA F + E  K   +A  R  +  +++++K+
Sbjct: 465 ------LKESISSQ-------------TILADFKMEE--KNENLAKKRCSEELVKQERKY 503

Query: 660 KLTRN----GHVIWKGSL 673
           + T N    G+   KG+L
Sbjct: 504 ENTDNKTELGNSDLKGNL 521


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
           2 [Homo sapiens]
          Length = 1336

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/258 (24%), Positives = 120/258 (46%), Gaps = 57/258 (22%)

Query: 431 ILEVESEPRAREVVDW-------RKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGH 483
           I++ + E + R+  +W       R+ E+E  K  E+ + I+E+RK+ KE  +K REK   
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365

Query: 484 LLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHE 543
              +K++I++  + +EQ+  K K     D++   +II   +  S          Y+  H 
Sbjct: 366 ---EKKNIVK--QEREQLISKEKIILREDAS-QQLIISSALKKS---------GYNNKH- 409

Query: 544 CELELVHFGVGDVSAN--DVNLAETFDGVIYGFNVN--AGNVIQQSAAKKGVKIKLHKII 599
             LE +    GD++ N  D N  +  D +++    +    NV +Q+  K+ +++K     
Sbjct: 410 LSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVK----- 464

Query: 600 YRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKF 659
                 L+E +SS+             +ILA F + E  K   +A  R  +  +++++K+
Sbjct: 465 ------LKESISSQ-------------TILADFKMEE--KNENLAKKRCSEELVKQERKY 503

Query: 660 KLTRN----GHVIWKGSL 673
           + T N    G+   KG+L
Sbjct: 504 ENTDNKTELGNSDLKGNL 521


>gi|94966752 elongation factor Tu GTP binding domain containing 1
           isoform 2 [Homo sapiens]
          Length = 1069

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 20/63 (31%), Positives = 35/63 (55%)

Query: 230 ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNK 289
           I  +D+PGH  FS+  +   ++ D  ++VV A +GV  QT   ++ A    +  +L +NK
Sbjct: 37  INLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINK 96

Query: 290 CDK 292
            D+
Sbjct: 97  IDR 99


>gi|239756373 PREDICTED: similar to elongation factor Tu GTP binding
           domain containing 1 [Homo sapiens]
          Length = 263

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)

Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
           + ++ HVD GKTTL D               K R       E   GIT    A  +   +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212

Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
           G +   I  +D+PGH  FS+  +   ++ D  ++VV A +GV  Q  E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260


>gi|239750897 PREDICTED: similar to elongation factor Tu GTP binding
           domain containing 1 [Homo sapiens]
          Length = 263

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)

Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
           + ++ HVD GKTTL D               K R       E   GIT    A  +   +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212

Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
           G +   I  +D+PGH  FS+  +   ++ D  ++VV A +GV  Q  E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260


>gi|239745282 PREDICTED: similar to elongation factor Tu GTP binding
           domain containing 1 [Homo sapiens]
          Length = 263

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 19/108 (17%)

Query: 183 VTIMGHVDHGKTTLLD---------------KFRKTQVAAVET-GGITQHIGAFLVSLPS 226
           + ++ HVD GKTTL D               K R       E   GIT    A  +   +
Sbjct: 153 ICVLAHVDRGKTTLADCLISSNGIISSHLAGKLRYMDSREDEQIRGITMKSSAISLHYAT 212

Query: 227 GEK---ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271
           G +   I  +D+PGH  FS+  +   ++ D  ++VV A +GV  Q  E
Sbjct: 213 GNEEYLINLIDSPGHMDFSSDVSTAVRICDGCIIVVDAVEGVCPQPRE 260


>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
          Length = 1037

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 30/136 (22%), Positives = 66/136 (48%), Gaps = 11/136 (8%)

Query: 442 EVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILR-------- 493
           E+ + R+  ++ EK Q  L  IE K + +++ + K +EKY  L+     +LR        
Sbjct: 436 ELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQ 495

Query: 494 -FLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVE-AILNIIDTYDASHECELELVHF 551
             + R+ Q+ L+ +EK+E + ++  +  +G      +  +L  +    A+ + EL+++  
Sbjct: 496 VSMARQAQVDLE-REKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQG 554

Query: 552 GVGDVSANDVNLAETF 567
            +   + ++ N A  F
Sbjct: 555 SLETSAQSEANWAAEF 570


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,575,462
Number of Sequences: 37866
Number of extensions: 1160445
Number of successful extensions: 6510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 5545
Number of HSP's gapped (non-prelim): 791
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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