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Search of human proteins with 53729327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53729327 nuclear receptor subfamily 6, group A, member 1
isoform 2 [Homo sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53729327 nuclear receptor subfamily 6, group A, member 1 isof... 985 0.0
gi|53729325 nuclear receptor subfamily 6, group A, member 1 isof... 972 0.0
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 168 1e-41
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 168 1e-41
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 157 2e-38
gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Hom... 151 1e-36
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo... 120 2e-27
gi|11415052 retinoid X receptor, beta [Homo sapiens] 120 3e-27
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 115 7e-26
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 115 9e-26
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 113 3e-25
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 113 4e-25
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 112 7e-25
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 111 1e-24
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 111 1e-24
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 111 2e-24
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 110 2e-24
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 110 2e-24
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 110 3e-24
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 110 4e-24
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 110 4e-24
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 110 4e-24
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 110 4e-24
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 110 4e-24
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 110 4e-24
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 110 4e-24
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom... 105 7e-23
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 105 9e-23
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 105 1e-22
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 103 3e-22
>gi|53729327 nuclear receptor subfamily 6, group A, member 1 isoform
2 [Homo sapiens]
Length = 475
Score = 985 bits (2546), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTNDRAEQRTCLICG 60
MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTNDRAEQRTCLICG
Sbjct: 1 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTNDRAEQRTCLICG 60
Query: 61 DRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMG 120
DRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMG
Sbjct: 61 DRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMG 120
Query: 121 MNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRA 180
MNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRA
Sbjct: 121 MNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRA 180
Query: 181 SESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARS 240
SESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARS
Sbjct: 181 SESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARS 240
Query: 241 LDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKL 300
LDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKL
Sbjct: 241 LDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKL 300
Query: 301 PFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEG 360
PFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEG
Sbjct: 301 PFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEG 360
Query: 361 MEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDF 420
MEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDF
Sbjct: 361 MEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDF 420
Query: 421 TEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE 475
TEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
Sbjct: 421 TEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE 475
>gi|53729325 nuclear receptor subfamily 6, group A, member 1 isoform
1 [Homo sapiens]
Length = 480
Score = 973 bits (2514), Expect = 0.0
Identities = 474/480 (98%), Positives = 475/480 (98%), Gaps = 5/480 (1%)
Query: 1 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGT----NDRAEQRTC 56
MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGT +DRAEQRTC
Sbjct: 1 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC 60
Query: 57 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC 116
LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
Sbjct: 61 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC 120
Query: 117 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP 176
LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
Sbjct: 121 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP 180
Query: 177 GNRASESNQPSPGSTLSS-RSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP 235
GNRASESNQPSPGSTLSS RSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP
Sbjct: 181 GNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP 240
Query: 236 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA 295
QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA
Sbjct: 241 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA 300
Query: 296 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR 355
WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR
Sbjct: 301 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR 360
Query: 356 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY 415
FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY
Sbjct: 361 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY 420
Query: 416 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE 475
ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
Sbjct: 421 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE 480
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 168 bits (425), Expect = 1e-41
Identities = 117/441 (26%), Positives = 197/441 (44%), Gaps = 52/441 (11%)
Query: 49 DRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRC 108
D + C +CGD+ +G HYG+++CE CKGFFKR++ N + Y C ++NC + + QR RC
Sbjct: 79 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC 138
Query: 109 QYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPV----QISEEEIERIMSGQEFEEEANH 164
YCR KCL +GM +A+R D M GGRNK GP+ + +++ + ++ + EA
Sbjct: 139 PYCRFQKCLSVGMKLEAVRADRMRGGRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMS 197
Query: 165 WSNHGDSDHSSPGNRASESNQPSPGSTLSSRSVELNGF--MAFREQYMGMSVPPH----- 217
+ + + S G L+ ++ + F + M++PPH
Sbjct: 198 QVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQG 257
Query: 218 ---YQYIPHLFSYSGHSPLLPQQARSLDPQSY----------SLIHQLLSAEDLEPLGTP 264
Y + P S + S+ SY S+ H +L EP P
Sbjct: 258 YQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEP-DEP 316
Query: 265 MLIEDGYAVTQAE-----------LFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTC 313
+ A Q E F L+C++AD+ LF + W + FF EL + D
Sbjct: 317 QVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMK 376
Query: 314 LLSSTWQELILLSSL---TVYSKQ-----IFGELADVTAKYSPSDEELHRFSDEGMEVIE 365
LL + W EL++L + V+ K+ + G+ D + S + L+ E++
Sbjct: 377 LLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVA 436
Query: 366 RLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKY 425
+L L+ E+ C+K + + D++ L + +E + ++ D+T Y
Sbjct: 437 KL-------RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNY 489
Query: 426 THQPNRFPDLMMCLPEIRYIA 446
Q +F L++ LPEIR I+
Sbjct: 490 PQQTEKFGQLLLRLPEIRAIS 510
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 168 bits (425), Expect = 1e-41
Identities = 117/441 (26%), Positives = 197/441 (44%), Gaps = 52/441 (11%)
Query: 49 DRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRC 108
D + C +CGD+ +G HYG+++CE CKGFFKR++ N + Y C ++NC + + QR RC
Sbjct: 33 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC 92
Query: 109 QYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPV----QISEEEIERIMSGQEFEEEANH 164
YCR KCL +GM +A+R D M GGRNK GP+ + +++ + ++ + EA
Sbjct: 93 PYCRFQKCLSVGMKLEAVRADRMRGGRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMS 151
Query: 165 WSNHGDSDHSSPGNRASESNQPSPGSTLSSRSVELNGF--MAFREQYMGMSVPPH----- 217
+ + + S G L+ ++ + F + M++PPH
Sbjct: 152 QVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQG 211
Query: 218 ---YQYIPHLFSYSGHSPLLPQQARSLDPQSY----------SLIHQLLSAEDLEPLGTP 264
Y + P S + S+ SY S+ H +L EP P
Sbjct: 212 YQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEP-DEP 270
Query: 265 MLIEDGYAVTQAE-----------LFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTC 313
+ A Q E F L+C++AD+ LF + W + FF EL + D
Sbjct: 271 QVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMK 330
Query: 314 LLSSTWQELILLSSL---TVYSKQ-----IFGELADVTAKYSPSDEELHRFSDEGMEVIE 365
LL + W EL++L + V+ K+ + G+ D + S + L+ E++
Sbjct: 331 LLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVA 390
Query: 366 RLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKY 425
+L L+ E+ C+K + + D++ L + +E + ++ D+T Y
Sbjct: 391 KL-------RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNY 443
Query: 426 THQPNRFPDLMMCLPEIRYIA 446
Q +F L++ LPEIR I+
Sbjct: 444 PQQTEKFGQLLLRLPEIRAIS 464
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 157 bits (397), Expect = 2e-38
Identities = 123/450 (27%), Positives = 187/450 (41%), Gaps = 95/450 (21%)
Query: 10 GGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELD--PGTNDRAE-QRTCLICGDRATGL 66
G GG GG ++ P + A D PG +R Q C++CGD+++G
Sbjct: 7 GWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGK 66
Query: 67 HYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAI 126
HYG+ +CEGCK FFKRSI Y C +++C + + RN+CQYCRL KC ++GM ++A+
Sbjct: 67 HYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAV 126
Query: 127 REDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQP 186
+ +P HS PG A+ S P
Sbjct: 127 QRGRIP----------------------------------------HSLPGAVAASSGSP 146
Query: 187 SPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSY 246
PGS L+ + + L P Q S
Sbjct: 147 -PGSALA--------------------------------AVASGGDLFPGQPVS------ 167
Query: 247 SLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCEL 306
LI QLL AE P G A +C LA LLF + W + PFF EL
Sbjct: 168 ELIAQLLRAEPY-PAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPEL 226
Query: 307 SIKDYTCLLSSTWQELILL----SSLTVYSKQIFGELADVTAKYSP-SDEELHRFSDEGM 361
+ D LL +W EL +L ++L +++ + LA +P + E F D+
Sbjct: 227 PVADQVALLRLSWSELFVLNAAQAALPLHTAPL---LAAAGLHAAPMAAERAVAFMDQVR 283
Query: 362 EVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFT 421
E++ K +L+V + EY C+KAI D GL+ + +E L ++ ++
Sbjct: 284 AFQEQV----DKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYV 339
Query: 422 EYKYTHQPNRFPDLMMCLPEIRYIAGKMVN 451
+Y QP RF L++ LP +R + +++
Sbjct: 340 RAQYPSQPQRFGRLLLRLPALRAVPASLIS 369
>gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Homo
sapiens]
Length = 461
Score = 151 bits (381), Expect = 1e-36
Identities = 111/436 (25%), Positives = 191/436 (43%), Gaps = 63/436 (14%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C +CGD+ +G HYG+++CE CKGFFKR++ N + Y C+ ++C + + QR RC +CR K
Sbjct: 13 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQK 72
Query: 116 CLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQ----EFEEEAN-------- 163
CL +GM +A+R D M GGRNK GP+ + +++ Q F+ E
Sbjct: 73 CLTVGMRLEAVRADRMRGGRNK-FGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPP 131
Query: 164 ---------HWSNHGDSDH----SSPGNRASESNQPSPGSTLSSRSVELNGFM------- 203
S HG P + P+ + L G++
Sbjct: 132 PPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGR 191
Query: 204 AFREQY-MGMSVPPH----YQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDL 258
A + +Y + PP Y Y P FS + P L Q L+P + ++L
Sbjct: 192 AIKSEYPEPYASPPQPGLPYGY-PEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQE 250
Query: 259 EPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSST 318
P Q F LLCR+AD+ + W ++ F EL + D LL +
Sbjct: 251 PTKSRP---------DQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNC 301
Query: 319 WQELILLSSL---TVYSKQ-----IFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYL 370
W EL++ + + K+ + G+ ++T + + LH E++ +L+
Sbjct: 302 WSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLL-- 359
Query: 371 YHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPN 430
L++ +E+ C+K I + D++ L + ++ ++ D+T Y H +
Sbjct: 360 -----ALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGD 414
Query: 431 RFPDLMMCLPEIRYIA 446
+F L++CL E+R ++
Sbjct: 415 KFQQLLLCLVEVRALS 430
>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
sapiens]
Length = 472
Score = 120 bits (302), Expect = 2e-27
Identities = 102/388 (26%), Positives = 162/388 (41%), Gaps = 73/388 (18%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C++CGDRA+G HY ++CEGCKGFF+RSI VY+C NCVM R +CQ CRL K
Sbjct: 127 CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRK 186
Query: 116 CLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSS 175
C +MGM + + + +Q + + + + H D
Sbjct: 187 CKEMGMLAECL------------LTEIQCKSKRLRK------------NVKQHAD----- 217
Query: 176 PGNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP 235
N+ S G L R V + + RE+ + P Q + H S + +P
Sbjct: 218 -----QTVNEDSEGRDL--RQV-TSTTKSCREK---TELTPDQQTLLHFIMDSYNKQRMP 266
Query: 236 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA 295
Q+ + ++ + SAE E F +L +A + +
Sbjct: 267 QEITN------KILKEEFSAE--------------------ENFLILTEMATNHVQVLVE 300
Query: 296 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR 355
+ KKLP F L +D LL + E + L S +++K++ +D+ EE R
Sbjct: 301 FTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLL-------EERIR 353
Query: 356 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY 415
S E I + Y +LK++ EEYA + AI L+ D + + +E+L +
Sbjct: 354 NSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLD 413
Query: 416 ICQDFTEYKYTHQPNRFPDLMMCLPEIR 443
+ Q + P F L+ L E+R
Sbjct: 414 VLQKLCKIHQPENPQHFACLLGRLTELR 441
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 120 bits (301), Expect = 3e-27
Identities = 71/185 (38%), Positives = 92/185 (49%), Gaps = 29/185 (15%)
Query: 12 GGGGGSAGFLEPPAA------LPPPPRNGFCQDELAELDPGTNDRAEQRTCLICGDRATG 65
GGG G ++PP PPPP PG A +R C ICGDR++G
Sbjct: 170 GGGSGPPEDVKPPVLGVRGLHCPPPPGG-----------PG----AGKRLCAICGDRSSG 214
Query: 66 LHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKA 125
HYG+ SCEGCKGFFKR+I Y C +K+C + ++QRNRCQYCR KCL GM R+A
Sbjct: 215 KHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREA 274
Query: 126 IREDGMPG----GRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRAS 181
++E+ G G + G E ++RI+ E E S+ G G S
Sbjct: 275 VQEERQRGKDKDGDGEGAGGAP-EEMPVDRIL---EAELAVEQKSDQGVEGPGGTGGSGS 330
Query: 182 ESNQP 186
N P
Sbjct: 331 SPNDP 335
Score = 77.0 bits (188), Expect = 3e-14
Identities = 49/171 (28%), Positives = 86/171 (50%), Gaps = 11/171 (6%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELAD 341
+C+ AD+ LF + W K++P F L + D LL + W EL L++S + S + +
Sbjct: 339 ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNEL-LIASFSHRSIDVRDGILL 397
Query: 342 VTAKYSPSDEELHRFSDEGMEV---IERLIY-LYHKFHQLKVSNEEYACMKAINFLNQDI 397
T + +HR S V +R++ L K +++ E C++AI N D
Sbjct: 398 ATGLH------VHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDA 451
Query: 398 RGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGK 448
+GL++ S++E L ++ + + + + KY Q RF L++ LP +R I K
Sbjct: 452 KGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLK 502
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 115 bits (289), Expect = 7e-26
Identities = 53/123 (43%), Positives = 74/123 (60%), Gaps = 2/123 (1%)
Query: 9 SGGGGGGGSAGFLEP-PAALPPPPRNGFCQDELAELDPGTNDRAE-QRTCLICGDRATGL 66
+GG G F P PA+L +E+ P + C +C D+++G
Sbjct: 30 TGGSCFAGLESFAWPQPASLQSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGY 89
Query: 67 HYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAI 126
HYG+ SCEGCKGFF+RSI VY C RDKNC++++ RNRCQYCRL KC ++GM+++A+
Sbjct: 90 HYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAV 149
Query: 127 RED 129
R D
Sbjct: 150 RND 152
Score = 38.5 bits (88), Expect = 0.013
Identities = 33/165 (20%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Query: 285 LADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTA 344
LA + + + + + K+LP F LSI D LL + ++++L T Y+ + + +
Sbjct: 222 LATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE--QDTMTFSD 279
Query: 345 KYSPSDEELHRFSDEGMEVIERLIYLY-HKFHQLKVSNEEYACMKAINFLNQDIRGLTSA 403
+ + ++H + G + L++ + + L++ + E + AI + D L
Sbjct: 280 GLTLNRTQMH---NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEP 336
Query: 404 SQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGK 448
++++L + + + + QP FP ++M + ++R I+ K
Sbjct: 337 EKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTK 381
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 115 bits (288), Expect = 9e-26
Identities = 103/403 (25%), Positives = 173/403 (42%), Gaps = 59/403 (14%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C ICGD+++G+HYG+I+CEGCKGFF+RS N Y C R +NC++ R RNRCQ+CRL K
Sbjct: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQK 69
Query: 116 CLQMGMNRKAIREDGMPGGRNKSI-GPVQISEEEIERIMSGQEFEEEA------------ 162
CL +GM+R A++ M + S+ VQ ++ ++ Q E EA
Sbjct: 70 CLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNG 129
Query: 163 -----NHWSNHGDSDH-----SSPGNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGM 212
N S + H S G +S QPSP + +++ G +++
Sbjct: 130 LSNLNNETSGTYANGHVIDLPKSEGYYNVDSGQPSPDQS----GLDMTGIKQIKQE---- 181
Query: 213 SVPPHYQY--IPHLFSYSGHSPLLPQQARSLDPQSYSLIHQLLSAEDLEPLGTPM--LIE 268
P Y +P+LF+YS + Q A + I Q + LE M L +
Sbjct: 182 ---PIYDLTSVPNLFTYSSFNN--GQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQ 236
Query: 269 DGYAVTQAELFALLCRLADELLFRQIA------------WIKKLPFFCELSIKDYTCLLS 316
+ E + E L++Q A + K++ F EL D LL
Sbjct: 237 LAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLK 296
Query: 317 STWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-FH 375
S E++L+ ++ + T + + F G + + + + K
Sbjct: 297 SGCLEVVLVRMCRAFNP------LNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLC 350
Query: 376 QLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQ 418
L+++ EE A + ++ D L ++++L ++ ++ Q
Sbjct: 351 SLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQ 393
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 113 bits (283), Expect = 3e-25
Identities = 48/107 (44%), Positives = 67/107 (62%), Gaps = 18/107 (16%)
Query: 23 PPAALPPPPRNGFCQDELAELDPGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKR 82
P + PPPP + + C +C D+++G HYG+ SCEGCKGFF+R
Sbjct: 75 PSSPSPPPPPRVY------------------KPCFVCNDKSSGYHYGVSSCEGCKGFFRR 116
Query: 83 SICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIRED 129
SI VY C RDKNC++++ RNRCQYCRL KC ++GM+++A+R D
Sbjct: 117 SIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRND 163
Score = 38.5 bits (88), Expect = 0.013
Identities = 33/165 (20%), Positives = 77/165 (46%), Gaps = 6/165 (3%)
Query: 285 LADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTA 344
LA + + + + + K+LP F LSI D LL + ++++L T Y+ + + +
Sbjct: 233 LATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPE--QDTMTFSD 290
Query: 345 KYSPSDEELHRFSDEGMEVIERLIYLY-HKFHQLKVSNEEYACMKAINFLNQDIRGLTSA 403
+ + ++H + G + L++ + + L++ + E + AI + D L
Sbjct: 291 GLTLNRTQMH---NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEP 347
Query: 404 SQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGK 448
++++L + + + + QP FP ++M + ++R I+ K
Sbjct: 348 EKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTK 392
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 113 bits (282), Expect = 4e-25
Identities = 105/415 (25%), Positives = 181/415 (43%), Gaps = 54/415 (13%)
Query: 35 FCQDELAELDPG-TNDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCS 93
+ Q E E+ G N + E C ICGD+++G+HYG+I+CEGCKGFF+RS + Y C
Sbjct: 84 YSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCP 143
Query: 94 RDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIER-- 151
R KNC++ R RNRCQ+CRL KCL +GM+R A++ M + S+ ++ + +++
Sbjct: 144 RQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSL-YAEVQKHRMQQQQ 202
Query: 152 -----------------IMSGQEFEEEANHWSNHGDSDHSSPGNRASES-------NQPS 187
+S E + SN+ D H+ G++A + QPS
Sbjct: 203 RDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDG-HTPEGSKADSAVSSFYLDIQPS 261
Query: 188 PGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHL-FSYSGHSPLLPQQARSLDPQSY 246
P + +++NG + P + P+ F+ SP + Q+
Sbjct: 262 PDQS----GLDINGI----KPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNI 313
Query: 247 SLIH----QLLSAEDLEPLGTPMLIE---DGYAVTQAELFALLCRL-ADELLFRQIAWIK 298
S H Q L E+L+ + ++ + Y Q E+ LC + E + + + K
Sbjct: 314 SKSHLETCQYL-REELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAK 372
Query: 299 KLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSD 358
++ F EL D LL + E++ + + Q KY+ D F
Sbjct: 373 RIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQ--NNTVYFDGKYASPDV----FKS 426
Query: 359 EGMEVIERLIYLYHK-FHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKR 412
G E ++ + K + ++ +E A A ++ D L ++E+L ++
Sbjct: 427 LGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQK 481
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 112 bits (280), Expect = 7e-25
Identities = 63/165 (38%), Positives = 86/165 (52%), Gaps = 25/165 (15%)
Query: 7 PPSGGGGGGGSAGFLEPPAAL--------------PPPPRNGFCQDELAELDPGTNDRAE 52
PPSG + PP++ P P G PG+
Sbjct: 79 PPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGS---LV 135
Query: 53 QRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCR 112
+ C ICGDR++G HYG+ SCEGCKGFFKR+I +Y C +K+C++ ++QRNRCQYCR
Sbjct: 136 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCR 195
Query: 113 LLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQE 157
KCL MGM R+A++E+ R +S + +E E E SG E
Sbjct: 196 YQKCLVMGMKREAVQEE-----RQRS---RERAESEAECATSGHE 232
Score = 85.5 bits (210), Expect = 1e-16
Identities = 50/171 (29%), Positives = 90/171 (52%), Gaps = 11/171 (6%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELAD 341
+C AD+ LF + W K++P F +L+++D LL + W EL L++S + S + +
Sbjct: 269 ICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNEL-LIASFSHRSVSVQDGILL 327
Query: 342 VTAKYSPSDEELHRFSDEGM---EVIERLIY-LYHKFHQLKVSNEEYACMKAINFLNQDI 397
T + +HR S + +R++ L K +++ E C++AI N D
Sbjct: 328 ATGLH------VHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDA 381
Query: 398 RGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGK 448
+GL++ S++E L ++ + + +T+ KY QP RF L++ LP +R I K
Sbjct: 382 KGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLK 432
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 111 bits (278), Expect = 1e-24
Identities = 113/455 (24%), Positives = 190/455 (41%), Gaps = 67/455 (14%)
Query: 5 EPPPSGGGGGGGS---------AGFLEPPAALPPPPRNGFCQDE--LAELDPGTNDRAEQ 53
EP SG GS A EPPA P R + ++ + E
Sbjct: 14 EPGSSGADAAAGSRETPLNQESARKSEPPA---PVRRQSYSSTSRGISVTKKTHTSQIEI 70
Query: 54 RTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRL 113
C ICGD+++G+HYG+I+CEGCKGFF+RS + Y C R KNC++ R RNRCQ+CRL
Sbjct: 71 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRL 130
Query: 114 LKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIER-------------------IMS 154
KCL +GM+R A++ M + S+ ++ + +++ +S
Sbjct: 131 QKCLAVGMSRDAVKFGRMSKKQRDSL-YAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNIS 189
Query: 155 GQEFEEEANHWSNHGDSDHSSPGNRASES-------NQPSPGSTLSSRSVELNGFMAFRE 207
E + SN+ D H+ G++A + QPSP + +++NG +
Sbjct: 190 ANGLTELHDDLSNYIDG-HTPEGSKADSAVSSFYLDIQPSPDQS----GLDINGI----K 240
Query: 208 QYMGMSVPPHYQYIPHL-FSYSGHSPLLPQQARSLDPQSYSLIH----QLLSAEDLEPLG 262
P + P+ F+ SP + Q+ S H Q L E+L+ +
Sbjct: 241 PEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYL-REELQQIT 299
Query: 263 TPMLIE---DGYAVTQAELFALLCRL-ADELLFRQIAWIKKLPFFCELSIKDYTCLLSST 318
++ + Y Q E+ LC + E + + + K++ F EL D LL +
Sbjct: 300 WQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAG 359
Query: 319 WQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-FHQL 377
E++ + + Q KY+ D F G E ++ + K +
Sbjct: 360 SLEVVFIRMCRAFDSQ--NNTVYFDGKYASPDV----FKSLGCEDFISFVFEFGKSLCSM 413
Query: 378 KVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKR 412
++ +E A A ++ D L ++E+L ++
Sbjct: 414 HLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQK 448
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 111 bits (278), Expect = 1e-24
Identities = 47/107 (43%), Positives = 67/107 (62%), Gaps = 20/107 (18%)
Query: 23 PPAALPPPPRNGFCQDELAELDPGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKR 82
PP+ LPPP + C +C D+++G HYG+ +CEGCKGFF+R
Sbjct: 68 PPSPLPPP--------------------RVYKPCFVCQDKSSGYHYGVSACEGCKGFFRR 107
Query: 83 SICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIRED 129
SI +Y C RDKNCV+++ RNRCQYCRL KC ++GM+++++R D
Sbjct: 108 SIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRND 154
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 111 bits (277), Expect = 2e-24
Identities = 51/105 (48%), Positives = 71/105 (67%), Gaps = 4/105 (3%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C ICGDR++G HYG+ SCEGCKGFFKR++ Y C +K+C++ ++QRNRCQYCR K
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 116 CLQMGMNRKAIREDGMPG-GRNKSIGPVQISEEE---IERIMSGQ 156
CL MGM R+A++E+ G RN++ S E +ERI+ +
Sbjct: 195 CLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAE 239
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/171 (29%), Positives = 89/171 (52%), Gaps = 11/171 (6%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELAD 341
+C+ AD+ LF + W K++P F EL + D LL + W EL L++S + S + +
Sbjct: 268 ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNEL-LIASFSHRSIAVKDGILL 326
Query: 342 VTAKYSPSDEELHRFSDEGMEV---IERLIY-LYHKFHQLKVSNEEYACMKAINFLNQDI 397
T + +HR S V +R++ L K +++ E C++AI N D
Sbjct: 327 ATGLH------VHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDS 380
Query: 398 RGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGK 448
+GL++ +++E L ++ + + + ++KY QP RF L++ LP +R I K
Sbjct: 381 KGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLK 431
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 110 bits (276), Expect = 2e-24
Identities = 99/393 (25%), Positives = 172/393 (43%), Gaps = 53/393 (13%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C ICGD+++G+HYG+I+CEGCKGFF+RS + Y C R KNC++ R RNRCQ+CRL K
Sbjct: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
Query: 116 CLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIER-------------------IMSGQ 156
CL +GM+R A++ M + S+ ++ + +++ +S
Sbjct: 78 CLAVGMSRDAVKFGRMSKKQRDSL-YAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISAN 136
Query: 157 EFEEEANHWSNHGDSDHSSPGNRASES-------NQPSPGSTLSSRSVELNGFMAFREQY 209
E + SN+ D H+ G++A + QPSP + +++NG +
Sbjct: 137 GLTELHDDLSNYIDG-HTPEGSKADSAVSSFYLDIQPSPDQS----GLDINGI----KPE 187
Query: 210 MGMSVPPHYQYIPHL-FSYSGHSPLLPQQARSLDPQSYSLIH----QLLSAEDLEPLGTP 264
P + P+ F+ SP + Q+ S H Q L E+L+ +
Sbjct: 188 PICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYL-REELQQITWQ 246
Query: 265 MLIE---DGYAVTQAELFALLCRL-ADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQ 320
++ + Y Q E+ LC + E + + + K++ F EL D LL +
Sbjct: 247 TFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSL 306
Query: 321 ELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-FHQLKV 379
E++ + + Q KY+ D F G E ++ + K + +
Sbjct: 307 EVVFIRMCRAFDSQ--NNTVYFDGKYASPDV----FKSLGCEDFISFVFEFGKSLCSMHL 360
Query: 380 SNEEYACMKAINFLNQDIRGLTSASQLEQLNKR 412
+ +E A A ++ D L ++E+L ++
Sbjct: 361 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQK 393
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 110 bits (276), Expect = 2e-24
Identities = 99/393 (25%), Positives = 172/393 (43%), Gaps = 53/393 (13%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C ICGD+++G+HYG+I+CEGCKGFF+RS + Y C R KNC++ R RNRCQ+CRL K
Sbjct: 98 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 157
Query: 116 CLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIER-------------------IMSGQ 156
CL +GM+R A++ M + S+ ++ + +++ +S
Sbjct: 158 CLAVGMSRDAVKFGRMSKKQRDSL-YAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISAN 216
Query: 157 EFEEEANHWSNHGDSDHSSPGNRASES-------NQPSPGSTLSSRSVELNGFMAFREQY 209
E + SN+ D H+ G++A + QPSP + +++NG +
Sbjct: 217 GLTELHDDLSNYIDG-HTPEGSKADSAVSSFYLDIQPSPDQS----GLDINGI----KPE 267
Query: 210 MGMSVPPHYQYIPHL-FSYSGHSPLLPQQARSLDPQSYSLIH----QLLSAEDLEPLGTP 264
P + P+ F+ SP + Q+ S H Q L E+L+ +
Sbjct: 268 PICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYL-REELQQITWQ 326
Query: 265 MLIE---DGYAVTQAELFALLCRL-ADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQ 320
++ + Y Q E+ LC + E + + + K++ F EL D LL +
Sbjct: 327 TFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSL 386
Query: 321 ELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHK-FHQLKV 379
E++ + + Q KY+ D F G E ++ + K + +
Sbjct: 387 EVVFIRMCRAFDSQ--NNTVYFDGKYASPDV----FKSLGCEDFISFVFEFGKSLCSMHL 440
Query: 380 SNEEYACMKAINFLNQDIRGLTSASQLEQLNKR 412
+ +E A A ++ D L ++E+L ++
Sbjct: 441 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQK 473
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 110 bits (275), Expect = 3e-24
Identities = 54/132 (40%), Positives = 75/132 (56%), Gaps = 10/132 (7%)
Query: 10 GGGGGGGS----AGFLEPPAALPP-----PPRNGFCQDELAELDPGTNDRAEQRTCLICG 60
GGGGG G AG P P P G D+ + PG+ + C++CG
Sbjct: 32 GGGGGAGEQQQQAGSGAPHTPQTPGQPGAPATPGTAGDK-GQGPPGSGQSQQHIECVVCG 90
Query: 61 DRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMG 120
D+++G HYG +CEGCK FFKRS+ Y C ++NC + + RN+CQYCRL KCL++G
Sbjct: 91 DKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVG 150
Query: 121 MNRKAIREDGMP 132
M R+A++ MP
Sbjct: 151 MRREAVQRGRMP 162
Score = 85.9 bits (211), Expect = 7e-17
Identities = 51/171 (29%), Positives = 87/171 (50%), Gaps = 6/171 (3%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSK-QIFGELA 340
+C LA LLF + W + +PFF +L I D LL TW EL +L++ + LA
Sbjct: 219 ICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLA 278
Query: 341 DVTAKYSP-SDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRG 399
SP S + + F D + + + + K L V + EY+C+KAI D G
Sbjct: 279 AAGLHASPMSADRVVAFMDH-IRIFQEQV---EKLKALHVDSAEYSCLKAIVLFTSDACG 334
Query: 400 LTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMV 450
L+ A+ +E L ++ +++ +Y +QP+RF L++ LP +R ++ ++
Sbjct: 335 LSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVI 385
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 110 bits (274), Expect = 4e-24
Identities = 41/76 (53%), Positives = 60/76 (78%)
Query: 54 RTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRL 113
+ C +C D+++G HYG+ +CEGCKGFF+RSI VY C RDKNC++++ RNRCQYCRL
Sbjct: 86 KPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRL 145
Query: 114 LKCLQMGMNRKAIRED 129
KC ++GM+++++R D
Sbjct: 146 QKCFEVGMSKESVRND 161
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 110 bits (274), Expect = 4e-24
Identities = 41/76 (53%), Positives = 60/76 (78%)
Query: 54 RTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRL 113
+ C +C D+++G HYG+ +CEGCKGFF+RSI VY C RDKNC++++ RNRCQYCRL
Sbjct: 81 KPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRL 140
Query: 114 LKCLQMGMNRKAIRED 129
KC ++GM+++++R D
Sbjct: 141 QKCFEVGMSKESVRND 156
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 110 bits (274), Expect = 4e-24
Identities = 41/76 (53%), Positives = 60/76 (78%)
Query: 54 RTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRL 113
+ C +C D+++G HYG+ +CEGCKGFF+RSI VY C RDKNC++++ RNRCQYCRL
Sbjct: 86 KPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRL 145
Query: 114 LKCLQMGMNRKAIRED 129
KC ++GM+++++R D
Sbjct: 146 QKCFEVGMSKESVRND 161
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 110 bits (274), Expect = 4e-24
Identities = 49/117 (41%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 23 PPAALPPPPRNGFCQDELAELD--PGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFF 80
PP L P P E L P + + + TC +CGD A HYG+ +CEGCKGFF
Sbjct: 268 PPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFF 327
Query: 81 KRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNK 137
KR++ Y C +KNC + +++RNRCQYCR KCL +GM ++ +R D + G R +
Sbjct: 328 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGR 384
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 110 bits (274), Expect = 4e-24
Identities = 49/117 (41%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 23 PPAALPPPPRNGFCQDELAELD--PGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFF 80
PP L P P E L P + + + TC +CGD A HYG+ +CEGCKGFF
Sbjct: 257 PPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFF 316
Query: 81 KRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNK 137
KR++ Y C +KNC + +++RNRCQYCR KCL +GM ++ +R D + G R +
Sbjct: 317 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGR 373
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 110 bits (274), Expect = 4e-24
Identities = 49/117 (41%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 23 PPAALPPPPRNGFCQDELAELD--PGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFF 80
PP L P P E L P + + + TC +CGD A HYG+ +CEGCKGFF
Sbjct: 257 PPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFF 316
Query: 81 KRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNK 137
KR++ Y C +KNC + +++RNRCQYCR KCL +GM ++ +R D + G R +
Sbjct: 317 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGR 373
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 110 bits (274), Expect = 4e-24
Identities = 49/117 (41%), Positives = 68/117 (58%), Gaps = 2/117 (1%)
Query: 23 PPAALPPPPRNGFCQDELAELD--PGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFF 80
PP L P P E L P + + + TC +CGD A HYG+ +CEGCKGFF
Sbjct: 257 PPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDNAACQHYGVRTCEGCKGFF 316
Query: 81 KRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNK 137
KR++ Y C +KNC + +++RNRCQYCR KCL +GM ++ +R D + G R +
Sbjct: 317 KRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDSLKGRRGR 373
>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
sapiens]
Length = 615
Score = 105 bits (263), Expect = 7e-23
Identities = 39/77 (50%), Positives = 59/77 (76%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C++CGD+A+G HYG +SCEGCKGFFKRS+ Y C +++C++++ RNRCQ+CRL K
Sbjct: 136 CVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKK 195
Query: 116 CLQMGMNRKAIREDGMP 132
CL+MGM ++++ + P
Sbjct: 196 CLEMGMKMESVQSERKP 212
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLS--------SLTVYSK 333
+C A LLF + W + +P F L T L+ + W EL L SL+
Sbjct: 405 ICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILA 464
Query: 334 QIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFL 393
I L + + S + + + ME I +L + +L + EYA +KAI
Sbjct: 465 AIVNHLQNSIQEDKLSGDRIKQV----MEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLF 520
Query: 394 NQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM 449
+ D GLTS SQ+E+ ++ QD+ + Y+ R +++ LP +R ++ +
Sbjct: 521 SPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNI 576
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 105 bits (262), Expect = 9e-23
Identities = 56/149 (37%), Positives = 80/149 (53%), Gaps = 24/149 (16%)
Query: 3 RDEPPPSGGGGGGGSAGFLEPPAALPPP--------PRNGFCQDELAEL---------DP 45
+DE P G GS PP PPP P G A+ P
Sbjct: 12 QDEVP-----GSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGP 66
Query: 46 GTNDRAEQR--TCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRK 103
G++ + +Q+ C++CGD+++G HYG +CEGCK FFKRS+ Y C ++NC + +
Sbjct: 67 GSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQH 126
Query: 104 QRNRCQYCRLLKCLQMGMNRKAIREDGMP 132
RN+CQYCRL KCL++GM R+A++ MP
Sbjct: 127 HRNQCQYCRLKKCLKVGMRREAVQRGRMP 155
Score = 83.2 bits (204), Expect = 5e-16
Identities = 49/171 (28%), Positives = 85/171 (49%), Gaps = 6/171 (3%)
Query: 282 LCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSK-QIFGELA 340
+C LA +LF + W + +PFF +L I D LL TW EL +L++ + LA
Sbjct: 212 ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLA 271
Query: 341 DVTAKYSP-SDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRG 399
SP S + + F D + + + + K L V + EY+C+KAI D G
Sbjct: 272 AAGLHASPMSADRVVAFMDH-IRIFQEQV---EKLKALHVDSAEYSCLKAIVLFTSDACG 327
Query: 400 LTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMV 450
L+ + +E L ++ +++ +Y +QP RF L++ LP +R ++ ++
Sbjct: 328 LSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVI 378
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 105 bits (261), Expect = 1e-22
Identities = 46/98 (46%), Positives = 62/98 (63%)
Query: 30 PPRNGFCQDELAELDPGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRV 89
P R EL + E C ICGD+++G+HYG+I+CEGCKGFF+RS
Sbjct: 5 PQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAA 64
Query: 90 YRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIR 127
Y C+R +NC + R RNRCQ+CRL KCL +GM+R A++
Sbjct: 65 YSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVK 102
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 103 bits (258), Expect = 3e-22
Identities = 41/72 (56%), Positives = 56/72 (77%)
Query: 56 CLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLK 115
C ICGD+++G+HYG+I+CEGCKGFF+RS Y C+R +NC + R RNRCQ+CRL K
Sbjct: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
Query: 116 CLQMGMNRKAIR 127
CL +GM+R A++
Sbjct: 70 CLALGMSRDAVK 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,459,457
Number of Sequences: 37866
Number of extensions: 1104361
Number of successful extensions: 8389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 7717
Number of HSP's gapped (non-prelim): 527
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.