Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 51873055
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
(1184 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 2544 0.0
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 2521 0.0
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 645 0.0
gi|34734066 fibulin 1 isoform D [Homo sapiens] 539 e-153
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 534 e-151
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 533 e-151
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 300 4e-81
gi|24430141 fibrillin 1 precursor [Homo sapiens] 291 2e-78
gi|118572606 hemicentin 1 [Homo sapiens] 280 8e-75
gi|66346695 fibrillin 2 precursor [Homo sapiens] 266 7e-71
gi|56237021 fibrillin 3 precursor [Homo sapiens] 266 1e-70
gi|110347437 latent transforming growth factor beta binding prot... 265 1e-70
gi|110347412 latent transforming growth factor beta binding prot... 265 1e-70
gi|110347431 latent transforming growth factor beta binding prot... 265 1e-70
gi|19743803 fibulin 5 precursor [Homo sapiens] 262 2e-69
gi|4557733 latent transforming growth factor beta binding protei... 259 8e-69
gi|46249414 latent transforming growth factor beta binding prote... 249 1e-65
gi|46249412 latent transforming growth factor beta binding prote... 249 1e-65
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 243 8e-64
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 243 8e-64
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 243 8e-64
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 219 9e-57
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 219 9e-57
gi|194328809 latent transforming growth factor beta binding prot... 209 1e-53
gi|18497288 latent transforming growth factor beta binding prote... 209 1e-53
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 202 2e-51
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 201 4e-51
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 192 1e-48
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 2544 bits (6593), Expect = 0.0
Identities = 1184/1184 (100%), Positives = 1184/1184 (100%)
Query: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ
Sbjct: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
Query: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN
Sbjct: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
Query: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN
Sbjct: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
Query: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS
Sbjct: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
Query: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG
Sbjct: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
Query: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP
Sbjct: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
Query: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED
Sbjct: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
Query: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC
Sbjct: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
Query: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN
Sbjct: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
Query: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL
Sbjct: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA
Sbjct: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
Query: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI
Sbjct: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
Query: 721 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFL 780
NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFL
Sbjct: 721 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFL 780
Query: 781 CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP
Sbjct: 781 CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
Query: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI
Sbjct: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
Query: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY 960
DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY
Sbjct: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIY 960
Query: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ
Sbjct: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
Query: 1081 NSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTG 1140
NSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTG
Sbjct: 1081 NSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTG 1140
Query: 1141 VVYLQRAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1184
VVYLQRAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL
Sbjct: 1141 VVYLQRAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1184
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 2521 bits (6535), Expect = 0.0
Identities = 1184/1231 (96%), Positives = 1184/1231 (96%), Gaps = 47/1231 (3%)
Query: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ
Sbjct: 1 MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQ 60
Query: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN
Sbjct: 61 QGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPN 120
Query: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN
Sbjct: 121 CIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGN 180
Query: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS
Sbjct: 181 FSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLS 240
Query: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG
Sbjct: 241 TIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGG 300
Query: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP
Sbjct: 301 HRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAP 360
Query: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED
Sbjct: 361 SLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEED 420
Query: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC
Sbjct: 421 TDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC 480
Query: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN
Sbjct: 481 VSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPN 540
Query: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL
Sbjct: 541 LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
Query: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA
Sbjct: 601 PGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA 660
Query: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCE-- 718
LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCE
Sbjct: 661 LKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQ 720
Query: 719 ---------------------------------------------DINECVTDLHTCSRG 733
DINECVTDLHTCSRG
Sbjct: 721 DECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRG 780
Query: 734 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 793
EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR
Sbjct: 781 EHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 840
Query: 794 QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 853
QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG
Sbjct: 841 QRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 900
Query: 854 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 913
TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC
Sbjct: 901 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 960
Query: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL 973
QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL
Sbjct: 961 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQL 1020
Query: 974 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1033
AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT
Sbjct: 1021 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGT 1080
Query: 1034 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF 1093
HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF
Sbjct: 1081 HNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNF 1140
Query: 1094 QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD 1153
QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD
Sbjct: 1141 QTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRD 1200
Query: 1154 FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1184
FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL
Sbjct: 1201 FALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 1231
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 645 bits (1665), Expect = 0.0
Identities = 280/499 (56%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVSCED+NEC+T H+C GE C+NT+GS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 743 FHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 801
F C + +C GY L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+
Sbjct: 240 FRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 802 QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
QD GNC+DINEC S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+E
Sbjct: 300 QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE 359
Query: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
C CG+G C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTL
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 922 GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTC 980
GSY CSC+ GF L+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 981 TDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
DIDECA G +C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS
Sbjct: 480 EDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1040 ETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLV 1099
ETC NIQG FRCL FECP NY + + T+CER CH+ EC P RIT+Y L+F T +
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQA 599
Query: 1100 PAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDVE 1159
PA +FR+GP+ A GD++ L I GNEEG+F TR+++ ++GVV L + V EPRD L V+
Sbjct: 600 PAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVK 659
Query: 1160 MKLWRQGSVTTFLAKMHIF 1178
M L R G+V++F+AK+ IF
Sbjct: 660 MDLSRHGTVSSFVAKLFIF 678
Score = 259 bits (663), Expect = 8e-69
Identities = 190/589 (32%), Positives = 262/589 (44%), Gaps = 116/589 (19%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKAL-TCEPGYAL 757
C G+ A G +C DINEC++ C G C+NT GS+ C K + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 758 KD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINEC 814
+ C DVDECA C G C N+ GSF C+ C G+ D CVD+NEC
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCE----CKTGYYFDGISRMCVDVNEC 403
Query: 815 TSLSEPCR-PGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
P R G C NT+GSY C C+ G+ S DG C D+NEC + C Q
Sbjct: 404 QRY--PGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGRSCEDINECSSS--PC--SQ 452
Query: 874 VCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNEC-WASPGRLCQHTCENTLGSYRCSC-AS 930
C N+ GSY+C C+ G+Q D G C D++EC + G +C + C N GS++CSC +S
Sbjct: 453 ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS 512
Query: 931 GFLLAADGKRCEDVNECEA--QRCS--QECANIYGSYQCY---CRQGYQ 972
G+ LA +G+ C+D++EC CS + C NI G ++C C + Y+
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 122 bits (305), Expect = 3e-27
Identities = 119/403 (29%), Positives = 159/403 (39%), Gaps = 79/403 (19%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDINECV 724
N C + PC Q C+ V GS C C GY + DGV+CEDI+EC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 --TDLHTCSRGEHCVNTLGSFHCYKALTC-EPGYALKDG--ECEDVDECAMGTHTCQPGF 779
T H CS C+N GSF C +C GY L C+D+DEC G H C
Sbjct: 487 LPTGGHICS--YRCINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 780 LCQNTKGSFYCQARQRCMDGFLQDPEGNCVDI-----NECTSL 817
C N +G F C A + C + + + C + EC+ L
Sbjct: 541 TCFNIQGGFRCLAFE-CPENYRRSAATRCERLPCHENRECSKL 582
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 539 bits (1388), Expect = e-153
Identities = 257/522 (49%), Positives = 333/522 (63%), Gaps = 22/522 (4%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVSCED+NEC+T H+C GE C+NT+GS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 743 FHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 801
F C + +C GY L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+
Sbjct: 240 FRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 802 QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
QD GNC+DINEC S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+E
Sbjct: 300 QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE 359
Query: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
C CG+G C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTL
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 922 GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTC 980
GSY CSC+ GF L+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 981 TDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
DIDECA G +C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS
Sbjct: 480 EDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1040 ETCHNIQGSFRCLRFECPPNY------VQVSKT---KCERTTCHDFLECQNSPAR-ITHY 1089
ETC NIQG FRCL FECP NY +Q KT +C ++ + + C P I+H
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHT 599
Query: 1090 QLNFQT--GLLVPAHIF---RIGPAPAFTGDTIALNIIKGNEEGYFG--TRRLNAYT-GV 1141
++ T P I I P + I +I +GN F R ++ T GV
Sbjct: 600 VISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGV 659
Query: 1142 VYLQRAVLEPRDFALDVEMKLWRQGSVT-TFLAKMHIFFTTF 1182
V R ++ P L +EM G V+ + +HIF + +
Sbjct: 660 VRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEY 701
Score = 259 bits (663), Expect = 8e-69
Identities = 190/589 (32%), Positives = 262/589 (44%), Gaps = 116/589 (19%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKAL-TCEPGYAL 757
C G+ A G +C DINEC++ C G C+NT GS+ C K + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 758 KD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINEC 814
+ C DVDECA C G C N+ GSF C+ C G+ D CVD+NEC
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCE----CKTGYYFDGISRMCVDVNEC 403
Query: 815 TSLSEPCR-PGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
P R G C NT+GSY C C+ G+ S DG C D+NEC + C Q
Sbjct: 404 QRY--PGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGRSCEDINECSSS--PC--SQ 452
Query: 874 VCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNEC-WASPGRLCQHTCENTLGSYRCSC-AS 930
C N+ GSY+C C+ G+Q D G C D++EC + G +C + C N GS++CSC +S
Sbjct: 453 ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS 512
Query: 931 GFLLAADGKRCEDVNECEA--QRCS--QECANIYGSYQCY---CRQGYQ 972
G+ LA +G+ C+D++EC CS + C NI G ++C C + Y+
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 121 bits (304), Expect = 3e-27
Identities = 118/404 (29%), Positives = 159/404 (39%), Gaps = 74/404 (18%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDINECV 724
N C + PC Q C+ V GS C C GY + DGV+CEDI+EC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 --TDLHTCSRGEHCVNTLGSFHCYKALTC-EPGYALKDG--ECEDVDECAMGTHTCQPGF 779
T H CS C+N GSF C +C GY L C+D+DEC G H C
Sbjct: 487 LPTGGHICS--YRCINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 780 LCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRP 823
C N +G F C A + C + + + + + + CRP
Sbjct: 541 TCFNIQGGFRCLAFE-CPENYRRSAATLQQEKTDTVRCIKSCRP 583
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 534 bits (1375), Expect = e-151
Identities = 225/388 (57%), Positives = 282/388 (72%), Gaps = 3/388 (0%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVSCED+NEC+T H+C GE C+NT+GS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 743 FHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 801
F C + +C GY L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+
Sbjct: 240 FRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 802 QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
QD GNC+DINEC S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+E
Sbjct: 300 QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE 359
Query: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
C CG+G C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTL
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 922 GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTC 980
GSY CSC+ GF L+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 981 TDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
DIDECA G +C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS
Sbjct: 480 EDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1040 ETCHNIQGSFRCLRFECPPNYVQVSKTK 1067
ETC NIQG FRCL FECP NY + + T+
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAATQ 567
Score = 259 bits (663), Expect = 8e-69
Identities = 190/589 (32%), Positives = 262/589 (44%), Gaps = 116/589 (19%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKAL-TCEPGYAL 757
C G+ A G +C DINEC++ C G C+NT GS+ C K + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 758 KD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINEC 814
+ C DVDECA C G C N+ GSF C+ C G+ D CVD+NEC
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCE----CKTGYYFDGISRMCVDVNEC 403
Query: 815 TSLSEPCR-PGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
P R G C NT+GSY C C+ G+ S DG C D+NEC + C Q
Sbjct: 404 QRY--PGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGRSCEDINECSSS--PC--SQ 452
Query: 874 VCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNEC-WASPGRLCQHTCENTLGSYRCSC-AS 930
C N+ GSY+C C+ G+Q D G C D++EC + G +C + C N GS++CSC +S
Sbjct: 453 ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS 512
Query: 931 GFLLAADGKRCEDVNECEA--QRCS--QECANIYGSYQCY---CRQGYQ 972
G+ LA +G+ C+D++EC CS + C NI G ++C C + Y+
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 120 bits (301), Expect = 8e-27
Identities = 114/373 (30%), Positives = 148/373 (39%), Gaps = 73/373 (19%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDINECV 724
N C + PC Q C+ V GS C C GY + DGV+CEDI+EC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 --TDLHTCSRGEHCVNTLGSFHCYKALTC-EPGYALKDG--ECEDVDECAMGTHTCQPGF 779
T H CS C+N GSF C +C GY L C+D+DEC G H C
Sbjct: 487 LPTGGHICS--YRCINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 780 LCQNTKGSFYCQA 792
C N +G F C A
Sbjct: 541 TCFNIQGGFRCLA 553
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 533 bits (1374), Expect = e-151
Identities = 225/387 (58%), Positives = 281/387 (72%), Gaps = 3/387 (0%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C+ GPCKQ C G +CSCF GY +++DGVSCED+NEC+T H+C GE C+NT+GS
Sbjct: 180 CRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGS 239
Query: 743 FHCYKALTCEPGYAL-KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL 801
F C + +C GY L +D C+D+DEC G H C P F+CQNT GSF C+ + +C GF+
Sbjct: 240 FRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 802 QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
QD GNC+DINEC S+S PC G +CINT GSYTCQ+N C RGYH +++GT+CVDV+E
Sbjct: 300 QDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDE 359
Query: 862 CETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
C CG+G C N PGS+RC+CK G+ D R C+DVNEC PGRLC H CENTL
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 922 GSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAE-DGHTC 980
GSY CSC+ GF L+ DG+ CED+NEC + CSQECAN+YGSYQCYCR+GYQL++ DG TC
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 981 TDIDECA-QGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
DIDECA G +C++RC+N+PGS+QC+CP GY + NGR+C+D+DEC G HNCS
Sbjct: 480 EDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSIN 539
Query: 1040 ETCHNIQGSFRCLRFECPPNYVQVSKT 1066
ETC NIQG FRCL FECP NY + + T
Sbjct: 540 ETCFNIQGGFRCLAFECPENYRRSAAT 566
Score = 259 bits (663), Expect = 8e-69
Identities = 190/589 (32%), Positives = 262/589 (44%), Gaps = 116/589 (19%)
Query: 441 LIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGE 500
L+E CCA G + A +C +P + TE CR Q CC S L+E C G+ A E +
Sbjct: 32 LLEACCADGHRMATHQKDC-SLPYA-TESKECRMVQEQCCHSQLEELHCATGISLANEQD 89
Query: 501 TCGAE--DNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG--- 555
C DN S + K+CC CC LG +A+GQSCE + +GY C V +CC
Sbjct: 90 RCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQE 149
Query: 556 ---------EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAE---------LP 597
+E + EV E R ++ G E L
Sbjct: 150 TGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLS 209
Query: 598 NSLPGDDQDECLLLPGELCQ--HLCINTVGSYHC----ACFPGFSLQDDGRTCRPEGHPP 651
+ + +D +EC+ C+ CINTVGS+ C +C G+ L +D
Sbjct: 210 DGVSCEDVNECIT-GSHSCRLGESCINTVGSFRCQRDSSCGTGYELTED----------- 257
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ---------VCSTVGGSAIC 702
N+CKD C+ +C GS C
Sbjct: 258 -----------------------------NSCKDIDECESGIHNCLPDFICQNTLGSFRC 288
Query: 703 ----SCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKAL-TCEPGYAL 757
C G+ A G +C DINEC++ C G C+NT GS+ C K + C GY L
Sbjct: 289 RPKLQCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHL 347
Query: 758 KD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINEC 814
+ C DVDECA C G C N+ GSF C+ C G+ D CVD+NEC
Sbjct: 348 NEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCE----CKTGYYFDGISRMCVDVNEC 403
Query: 815 TSLSEPCR-PGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQ 873
P R G C NT+GSY C C+ G+ S DG C D+NEC + C Q
Sbjct: 404 QRY--PGRLCGHKCENTLGSYLCS-----CSVGFRLSVDGRSCEDINECSSS--PC--SQ 452
Query: 874 VCHNLPGSYRCDCKAGFQ-RDAFGRGCIDVNEC-WASPGRLCQHTCENTLGSYRCSC-AS 930
C N+ GSY+C C+ G+Q D G C D++EC + G +C + C N GS++CSC +S
Sbjct: 453 ECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSS 512
Query: 931 GFLLAADGKRCEDVNECEA--QRCS--QECANIYGSYQCY---CRQGYQ 972
G+ LA +G+ C+D++EC CS + C NI G ++C C + Y+
Sbjct: 513 GYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 120 bits (301), Expect = 8e-27
Identities = 114/373 (30%), Positives = 148/373 (39%), Gaps = 73/373 (19%)
Query: 436 GSTKDLIETCCAAGQQWAIDN-----DECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSC 489
GS + ++ C G + DN DEC + D +C+ T C LQ C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ---C 294
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESN-PNLG--YPC 545
+G + G + N+ IS C + EG +C+ N PN G Y
Sbjct: 295 KSGFIQDALGNCI--DINECLSISAPCPIGHTC-----INTEGSYTCQKNVPNCGRGYHL 347
Query: 546 NHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
N EG + V E P EP R + + R G + + + D
Sbjct: 348 NE------EGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD-V 400
Query: 606 DECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
+EC PG LC H C NT+GSY C+C GF L DGR+C
Sbjct: 401 NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE-------------------- 440
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM-ADGVSCEDINECV 724
N C + PC Q C+ V GS C C GY + DGV+CEDI+EC
Sbjct: 441 -------------DINEC-SSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA 486
Query: 725 --TDLHTCSRGEHCVNTLGSFHCYKALTC-EPGYALKDG--ECEDVDECAMGTHTCQPGF 779
T H CS C+N GSF C +C GY L C+D+DEC G H C
Sbjct: 487 LPTGGHICS--YRCINIPGSFQC----SCPSSGYRLAPNGRNCQDIDECVTGIHNCSINE 540
Query: 780 LCQNTKGSFYCQA 792
C N +G F C A
Sbjct: 541 TCFNIQGGFRCLA 553
>gi|190343004 EGF-containing fibulin-like extracellular matrix protein
2 [Homo sapiens]
Length = 443
Score = 300 bits (769), Expect = 4e-81
Identities = 154/390 (39%), Positives = 212/390 (54%), Gaps = 36/390 (9%)
Query: 796 CMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTC------------------ 836
C DG+ DP+ +C D+NEC ++ E C+ CIN G Y C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 837 ----QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 892
++P C GY DD CVDV+EC +H C Q CHNLPGSY+C C G+++
Sbjct: 99 PVPPAQHPNPCPPGYEP-DDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRK 157
Query: 893 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE-AQR 951
G C+D++EC R CQH C N GS+RC C GF L + + C DVNEC+
Sbjct: 158 --IGPECVDIDECRY---RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAP 212
Query: 952 CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPE 1011
C Q C N YG++ C C QGY+L DG +C+DIDEC+ + LC +RC+N PG + C CP
Sbjct: 213 CEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSS-YLCQYRCVNEPGRFSCHCP- 270
Query: 1012 QGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFE-CPPNYVQVSKTKCER 1070
QGY + A R C+D+DEC G H CSEA+TC N G +RC+ C Y+QVS+ +C
Sbjct: 271 QGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLC 329
Query: 1071 TTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYF 1130
+ C+ P+ I H + + VPA +F+I + G A I GN +G F
Sbjct: 330 PASNPL--CREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDF 387
Query: 1131 GTRRLNAYTGVVYLQRAVLEPRDFALDVEM 1160
R++N + ++ L R V PR++ LD+EM
Sbjct: 388 YIRQINNVSAMLVLARPVTGPREYVLDLEM 417
Score = 162 bits (411), Expect = 1e-39
Identities = 107/311 (34%), Positives = 143/311 (45%), Gaps = 54/311 (17%)
Query: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT------------- 750
C GY D C D+NEC+T C C+N G + C
Sbjct: 39 CTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 98
Query: 751 ----------CEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG 799
C PGY D + C DVDECA H C+P C N GS+ C C DG
Sbjct: 99 PVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC----TCPDG 154
Query: 800 FLQ-DPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD 858
+ + PE CVDI+EC C+ C+N GS+ CQ C G+ + CVD
Sbjct: 155 YRKIGPE--CVDIDECR--YRYCQ--HRCVNLPGSFRCQ-----CEPGFQLGPNNRSCVD 203
Query: 859 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCE 918
VNEC+ G C Q C N G++ C C G++ G C D++EC S LCQ+ C
Sbjct: 204 VNECDMGA-PC--EQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYS-SYLCQYRCV 259
Query: 919 NTLGSYRCSCASGFLLAADGKRCEDVNECE--AQRCS--QECANIYGSYQCY----CRQG 970
N G + C C G+ L A + C+D++ECE A +CS Q C N +G Y+C C +
Sbjct: 260 NEPGRFSCHCPQGYQLLAT-RLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEP 318
Query: 971 Y-QLAEDGHTC 980
Y Q++E+ C
Sbjct: 319 YIQVSENRCLC 329
Score = 122 bits (306), Expect = 2e-27
Identities = 104/412 (25%), Positives = 145/412 (35%), Gaps = 120/412 (29%)
Query: 432 SSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCM- 490
+SP+ S + T C G +W D+ C ++ E T C+ + C+++ C+
Sbjct: 25 ASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMK--CINHYGGYLCLP 82
Query: 491 --AGVLGAKEGE-------------TCGA----EDNDSCGISLYKQCCDCCGLGLRVRAE 531
A V+ GE C +D DSC D C L
Sbjct: 83 RSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSC------VDVDECAQALHDCRP 136
Query: 532 GQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLG 591
Q C + P Y C +C +G + G E +
Sbjct: 137 SQDCHNLPG-SYQC-----TCPDGYRKI------------------------GPECV--- 163
Query: 592 TEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPP 651
D DEC CQH C+N GS+ C C PGF L + R+C
Sbjct: 164 ------------DIDECRY---RYCQHRCVNLPGSFRCQCEPGFQLGPNNRSC------- 201
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM 711
N C PC+Q C G+ +C C GY +
Sbjct: 202 --------------------------VDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELH 235
Query: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE-CEDVDECAM 770
DG SC DI+EC + C CVN G F C+ C GY L C+D+DEC
Sbjct: 236 RDGFSCSDIDECSYSSYLCQ--YRCVNEPGRFSCH----CPQGYQLLATRLCQDIDECES 289
Query: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCR 822
G H C C N G + C RC++ ++Q E C+ C + + CR
Sbjct: 290 GAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCL----CPASNPLCR 337
Score = 107 bits (267), Expect = 7e-23
Identities = 80/237 (33%), Positives = 104/237 (43%), Gaps = 52/237 (21%)
Query: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRC---------- 926
P SY +C G++ D + C DVNEC P C + C N G Y C
Sbjct: 33 PDSYT-ECTDGYEWDPDSQHCRDVNECLTIP-EACKGEMKCINHYGGYLCLPRSAAVIND 90
Query: 927 -----------------SCASGFLLAADGKRCEDVNECEAQ----RCSQECANIYGSYQC 965
C G+ D C DV+EC R SQ+C N+ GSYQC
Sbjct: 91 LHGEGPPPPVPPAQHPNPCPPGY-EPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQC 149
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
C GY+ + G C DIDEC C RC+N+PGS++C C E G+ + N RSC D
Sbjct: 150 TCPDGYR--KIGPECVDIDECRYR---YCQHRCVNLPGSFRCQC-EPGFQLGPNNRSCVD 203
Query: 1026 VDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
V+EC +G C + C N G+F C C Y + + +C D EC S
Sbjct: 204 VNECDMGA-PCE--QRCFNSYGTFLC---RCHQGY----ELHRDGFSCSDIDECSYS 250
Score = 98.2 bits (243), Expect = 4e-20
Identities = 84/277 (30%), Positives = 112/277 (40%), Gaps = 51/277 (18%)
Query: 597 PNSLPGDDQDECLLLPGELC--QHLCINTVGSYHCACFPGFSLQD-DGRTCRPEGHPPQP 653
P+S D +ECL +P E C + CIN G Y C + D G P P Q
Sbjct: 47 PDSQHCRDVNECLTIP-EACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQH 105
Query: 654 EAPQEPALK----------SEFSQVASNTIP------LPLPQPNTCKDN----GP----- 688
P P + E +Q + P LP TC D GP
Sbjct: 106 PNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDI 165
Query: 689 -------CKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLG 741
C+ C + GS C C PG+ + + SC D+NEC C + C N+ G
Sbjct: 166 DECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCE--QRCFNSYG 222
Query: 742 SFHCYKALTCEPGYAL-KDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG 799
+F C C GY L +DG C D+DEC+ ++ CQ + C N G F C C G
Sbjct: 223 TFLC----RCHQGYELHRDGFSCSDIDECSYSSYLCQ--YRCVNEPGRFSC----HCPQG 272
Query: 800 FLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTC 836
+ C DI+EC S + C +C+N G Y C
Sbjct: 273 YQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 291 bits (746), Expect = 2e-78
Identities = 179/509 (35%), Positives = 246/509 (48%), Gaps = 59/509 (11%)
Query: 595 ELPNSLPG-DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGH--- 649
E+ N P D +EC ++P LC H C NT+GS+ C C GF+L + R C
Sbjct: 1018 EITNGKPFFKDINECKMIPS-LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRI 1076
Query: 650 -PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSA 700
P Q +F C D C++ VC GS
Sbjct: 1077 SPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSY 1136
Query: 701 ICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG 760
C C PG+ + + +C DINEC H C G CVN +G + C C PGY
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGR-CVNLIGKYQC----ACNPGYHSTPD 1191
Query: 761 E--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSL 817
C D+DEC++ C+ C N++GS+ C C GF L + +C DI+EC
Sbjct: 1192 RLFCVDIDECSIMNGGCET--FCTNSEGSYECS----CQPGFALMPDQRSCTDIDECEDN 1245
Query: 818 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 877
C G C N G Y C +C G+ AS+D CVDVNEC+ + C G C N
Sbjct: 1246 PNICDGG-QCTNIPGEYRC-----LCYDGFMASEDMKTCVDVNECDLNPNICLSG-TCEN 1298
Query: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAA 936
GS+ C C G+ GC D+NEC +H C NT GS++CSC+ G++
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWI--G 1356
Query: 937 DGKRCEDVNECE--AQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGI 992
DG +C D++EC CSQ +C N GSY+C C++GY DG TCTD+DEC++ +
Sbjct: 1357 DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGY--TGDGFTCTDLDECSENLNL 1414
Query: 993 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
+CLN PG Y+C C + G+ +A+G++C+D+DEC+L N TCHN+ G FRC
Sbjct: 1415 CGNGQCLNAPGGYRCEC-DMGFVPSADGKACEDIDECSL--PNICVFGTCHNLPGLFRC- 1470
Query: 1053 RFECPPNYVQVSKTKCERT--TCHDFLEC 1079
EC Y + +R+ C D EC
Sbjct: 1471 --ECEIGY------ELDRSGGNCTDVNEC 1491
Score = 252 bits (644), Expect = 1e-66
Identities = 185/603 (30%), Positives = 248/603 (41%), Gaps = 106/603 (17%)
Query: 445 CCAAGQQWAIDNDECLEIPESGTED--------------------------NVCRTAQRH 478
CC+ G W +EC E P T + N C+
Sbjct: 981 CCSVGAAWG--TEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSL 1038
Query: 479 C----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQS 534
C C + + C A + E D D C IS D CG G V G
Sbjct: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISP-----DLCGRGQCVNTPGDF 1093
Query: 535 CESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEA 594
E + GY +M+ C + + E +R P E + R G +
Sbjct: 1094 -ECKCDEGYESGFMMMKNC-----MDIDECQRDPLLCRGGV-CHNTEGSYRCECPPGHQL 1146
Query: 595 ELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQP 653
PN D +EC L LC + C+N +G Y CAC PG+ D C
Sbjct: 1147 S-PNISACIDINECEL-SAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFC--------- 1195
Query: 654 EAPQEPALKSEFSQVASNTIPLPLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMA 712
+ C NG C+ C+ GS CSC PG+A+M
Sbjct: 1196 ------------------------VDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAM 770
D SC DI+EC + + C G+ C N G + C C G+ + C DV+EC +
Sbjct: 1232 DQRSCTDIDECEDNPNICDGGQ-CTNIPGEYRC----LCYDGFMASEDMKTCVDVNECDL 1286
Query: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFL-QDPEGNCVDINECTSLSEPCRPGFSCIN 829
+ C G C+NTKGSF C C G+ + + C DINEC + C C N
Sbjct: 1287 NPNICLSG-TCENTKGSFIC----HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
Query: 830 TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 889
T GS+ C C+ G+ DG KC D++EC G H C + C N GSYRC CK G
Sbjct: 1342 TAGSFKCS-----CSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEG 1394
Query: 890 FQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA 949
+ D F C D++EC + C N G YRC C GF+ +ADGK CED++EC
Sbjct: 1395 YTGDGF--TCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL 1452
Query: 950 QRCS--QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1007
C N+ G ++C C GY+L G CTD++EC + + C+N PGSY C
Sbjct: 1453 PNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCI-SGNCVNTPGSYIC 1511
Query: 1008 ACP 1010
CP
Sbjct: 1512 DCP 1514
Score = 251 bits (642), Expect = 2e-66
Identities = 205/685 (29%), Positives = 284/685 (41%), Gaps = 132/685 (19%)
Query: 455 DNDECLEIP---ESGTEDNVCRTAQRHCCVSY-LQEKSCMAGVLGAKEGETCGAEDNDSC 510
D DEC E+P + G N + Q C Y L E + + E ET G +C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD--DVNECETPGICGPGTC 1663
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEV------ 564
++ C C ++V + +L Y + C+GE + +
Sbjct: 1664 YNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY 1723
Query: 565 ------RRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH 618
+P E P A + G + G ++ LP D DEC +PG
Sbjct: 1724 NIGRAWNKPCEQCPIPSTDEFATLCGSQRP--GFVIDIYTGLPVDI-DECREIPGVCENG 1780
Query: 619 LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP 678
+CIN VGS+ C C GF D C
Sbjct: 1781 VCINMVGSFRCECPVGFFYNDKLLVCE--------------------------------- 1807
Query: 679 QPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHC 736
+ C++ C++ C GS C C PGY + G C D NEC + CS G+ C
Sbjct: 1808 DIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQ-C 1865
Query: 737 VNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 794
++T+GSF+C C G+ D + C D++EC C G C+NT GSF C
Sbjct: 1866 IDTVGSFYC----LCHTGFKTNDDQTMCLDINECE--RDACGNG-TCRNTIGSFNC---- 1914
Query: 795 RCMDGFLQDPEGNCVDINECTS-LSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 853
RC GF+ +C+D++EC S CR G CINTVGS+ CQ C GY + DG
Sbjct: 1915 RCNHGFILSHNNDCIDVDECASGNGNLCRNG-QCINTVGSFQCQ-----CNEGYEVAPDG 1968
Query: 854 TKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC 913
CVD+NEC +C G C NL GSYRC C G+ C D++EC P
Sbjct: 1969 RTCVDINECLLEPRKCAPG-TCQNLDGSYRCICPPGYSLQ--NEKCEDIDECVEEPEICA 2025
Query: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVN------ECEAQRCSQECANIYGSYQCYC 967
TC NT GS++C C GF L++ G+RC+D+ + E +CS + + +C C
Sbjct: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC 2085
Query: 968 R-QGYQLAEDGHTC-TDIDE-----CAQGAGIL------------------CTF-RCLNV 1001
+G + C T+ DE C G+GI+ C +C+N
Sbjct: 2086 ALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT 2145
Query: 1002 PGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL---RFECPP 1058
GSY+C CP GY + G C D DEC++G + C TC N+ G F C FE P
Sbjct: 2146 DGSYRCECP-FGYILA--GNECVDTDECSVG-NPCGNG-TCKNVIGGFECTCEEGFEPGP 2200
Query: 1059 NYVQVSKTKCERTTCHDFLECQNSP 1083
TC D EC +P
Sbjct: 2201 -----------MMTCEDINECAQNP 2214
Score = 246 bits (627), Expect = 1e-64
Identities = 174/576 (30%), Positives = 253/576 (43%), Gaps = 72/576 (12%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC--RPEGHPPQPEAPQEPAL 661
D++EC PG C+NT GSY C C GF+ + C EG+
Sbjct: 2291 DENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC----------- 2339
Query: 662 KSEFSQVASNTIPL------PLPQPNTCKDNG----PCKQVCSTVGGSAICSCFP-GYAI 710
F++V N + P+ + C D G P ++C G A P G
Sbjct: 2340 ---FTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGF 2396
Query: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDGECEDVDEC 768
M +G DI+EC C GE CVN GS+HC C+ GY + C D++EC
Sbjct: 2397 MTNGA---DIDECKVIHDVCRNGE-CVNDRGSYHCI----CKTGYTPDITGTSCVDLNEC 2448
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSC 827
C F+C+NT+GS+ C C G++ +G +C D++EC + C+ F C
Sbjct: 2449 NQAPKPCN--FICKNTEGSYQCS----CPKGYILQEDGRSCKDLDECATKQHNCQ--FLC 2500
Query: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
+NT+G +TC+ C G+ + T C+D NEC + ++ CG +C N PGS+ C+C+
Sbjct: 2501 VNTIGGFTCK-----CPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQ 2553
Query: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
GF D G C DV+EC CQH C+N +G YRCSC G+L +C D NEC
Sbjct: 2554 RGFSLDQTGSSCEDVDEC--EGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENEC 2611
Query: 948 -EAQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
A C C N GSY+C C G+Q + C DI+EC A C++ C N G Y
Sbjct: 2612 LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECG-SAQAPCSYGCSNTEGGY 2670
Query: 1006 QCACPE------QGYTMTANGRSCKDVDECALG--THNCSEAETCH--NIQGSFRCLRFE 1055
C CP QG+ ++ G + + G N E C+ I G + R
Sbjct: 2671 LCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKR 2730
Query: 1056 CPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGD 1115
N S + + T + + + N + + I + PA +
Sbjct: 2731 RSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNI-SHVSNKVRILELLPALTTLTN 2789
Query: 1116 TIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEP 1151
I GNE+G+F ++N G+ YL +P
Sbjct: 2790 HNRYLIESGNEDGFF---KINQKEGISYLHFTKKKP 2822
Score = 241 bits (615), Expect = 3e-63
Identities = 178/558 (31%), Positives = 241/558 (43%), Gaps = 97/558 (17%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
+D +EC P LC C+NT GSY C C G+ L++D R C+ E + +
Sbjct: 2205 EDINECAQNP-LLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK-------- 2255
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINE 722
+ C + + C + G+ +C C PGY DG C D NE
Sbjct: 2256 ------------------HDCTEK---QMECKNLIGTYMCICGPGYQRRPDGEGCVDENE 2294
Query: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE------CAMGTHTCQ 776
C T C G C+NT GS+ C C G+ + E +D + + CQ
Sbjct: 2295 CQTKPGICENGR-CLNTRGSYTC----ECNDGFTASPNQDECLDNREGYCFTEVLQNMCQ 2349
Query: 777 PGFLCQN--TKGSFYCQARQ----RCMDGFLQD--------PEG-----NCVDINECTSL 817
G +N TK C + C Q P G N DI+EC +
Sbjct: 2350 IGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVI 2409
Query: 818 SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHN 877
+ CR G C+N GSY C IC GY GT CVD+NEC C +C N
Sbjct: 2410 HDVCRNG-ECVNDRGSYHC-----ICKTGYTPDITGTSCVDLNECNQAPKPCNF--ICKN 2461
Query: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAAD 937
GSY+C C G+ GR C D++EC A+ CQ C NT+G + C C GF
Sbjct: 2462 TEGSYQCSCPKGYILQEDGRSCKDLDEC-ATKQHNCQFLCVNTIGGFTCKCPPGF--TQH 2518
Query: 938 GKRCEDVNEC--EAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL 993
C D NEC + C + C N GS+ C C++G+ L + G +C D+DEC
Sbjct: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE--GNHR 2576
Query: 994 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1053
C C N+ G Y+C+CP QGY C D +EC L H C A +CHN GS++C+
Sbjct: 2577 CQHGCQNIIGGYRCSCP-QGYLQHYQWNQCVDENEC-LSAHICGGA-SCHNTLGSYKCM- 2632
Query: 1054 FECPP--NYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL--VPAHIFRIGPA 1109
CP Y Q S C D EC ++ A ++ N + G L P FRIG
Sbjct: 2633 --CPAGFQYEQFS------GGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
Query: 1110 PAFTGDTIALNIIKGNEE 1127
+G + + +GN E
Sbjct: 2685 HCVSG----MGMGRGNPE 2698
Score = 236 bits (602), Expect = 1e-61
Identities = 185/572 (32%), Positives = 229/572 (40%), Gaps = 121/572 (21%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
+D DEC+ P C NT GS+ C C GFSL GR C Q K
Sbjct: 2012 EDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC-------QDLRMSYCYAK 2064
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNG-----PCKQVCSTVGGSA---ICSCFPGYAIMADG 714
E + +S Q C G PC ++C T A IC G + D
Sbjct: 2065 FEGGKCSSPKSRNHSKQECCCALKGEGWGDPC-ELCPTEPDEAFRQICPYGSGIIVGPDD 2123
Query: 715 VSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHT 774
S D++EC + C G+ C+NT GS+ C C GY L EC D DEC++G +
Sbjct: 2124 -SAVDMDEC-KEPDVCKHGQ-CINTDGSYRC----ECPFGYILAGNECVDTDECSVG-NP 2175
Query: 775 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSY 834
C G C+N G F C C +GF P C DINEC P F C+NT GSY
Sbjct: 2176 CGNG-TCKNVIGGFECT----CEEGFEPGPMMTCEDINECAQ--NPLLCAFRCVNTYGSY 2228
Query: 835 TCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV-CHNLPGSYRCDCKAGFQRD 893
C+ C GY +D C D +ECE G H C E Q+ C NL G+Y C C G+QR
Sbjct: 2229 ECK-----CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRR 2283
Query: 894 AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE--CEAQR 951
G GC+D NEC PG C NT GSY C C GF + + C D E C +
Sbjct: 2284 PDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEV 2343
Query: 952 CSQEC------ANIYGSYQCYCRQGYQLAEDGHTC----------------------TDI 983
C N +C C G C DI
Sbjct: 2344 LQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADI 2403
Query: 984 DECA--------------QGA--------------GILC-------------TFRCLNVP 1002
DEC +G+ G C F C N
Sbjct: 2404 DECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTE 2463
Query: 1003 GSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ 1062
GSYQC+CP +GY + +GRSCKD+DECA HNC C N G F C +CPP + Q
Sbjct: 2464 GSYQCSCP-KGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIGGFTC---KCPPGFTQ 2517
Query: 1063 VSKTKCERTTCHDFLE-------CQNSPARIT 1087
+ + C + CQN+P T
Sbjct: 2518 HHTSCIDNNECTSDINLCGSKGICQNTPGSFT 2549
Score = 219 bits (558), Expect = 1e-56
Identities = 207/698 (29%), Positives = 281/698 (40%), Gaps = 136/698 (19%)
Query: 433 SPEGSTKDLIETC------CAAGQQWAIDND-ECLEIPESGTEDNVCRTAQRHCCVSYLQ 485
+P+G T I C CA G +D C+ P ++ C CV +
Sbjct: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDE--CVE--E 2020
Query: 486 EKSCMAGVLGAKEGE-TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYP 544
+ C G EG C + S S ++C D + EG C S +
Sbjct: 2021 PEICALGTCSNTEGSFKCLCPEGFSLSSS-GRRCQDLRMSYCYAKFEGGKCSSPKSR--- 2076
Query: 545 CNHVMLSCC---EGE---EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPN 598
NH CC +GE +P + P EP + A R+ G+ +
Sbjct: 2077 -NHSKQECCCALKGEGWGDPCELC----PTEP----------DEAFRQICPYGSGIIVGP 2121
Query: 599 SLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQ 657
D DEC ++C+H CINT GSY C C G+ L G C
Sbjct: 2122 DDSAVDMDECK--EPDVCKHGQCINTDGSYRCECPFGYILA--GNEC------------- 2164
Query: 658 EPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVS 716
+ C PC C V G C+C G+ ++
Sbjct: 2165 --------------------VDTDECSVGNPCGNGTCKNVIGGFECTCEEGFE-PGPMMT 2203
Query: 717 CEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHT 774
CEDINEC + C+ CVNT GS+ C C GY L++ C+D DEC G H
Sbjct: 2204 CEDINECAQNPLLCAF--RCVNTYGSYEC----KCPVGYVLREDRRMCKDEDECEEGKHD 2257
Query: 775 C-QPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVG 832
C + C+N G++ C C G+ + P+G CVD NEC + C G C+NT G
Sbjct: 2258 CTEKQMECKNLIGTYMCI----CGPGYQRRPDGEGCVDENECQTKPGICENG-RCLNTRG 2312
Query: 833 SYTCQRNPLICARGYHASDDGTKCVDVNE--CETGV--HRCGEGQVCHNLPGSYRCDCKA 888
SYTC+ C G+ AS + +C+D E C T V + C G N C C
Sbjct: 2313 SYTCE-----CNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDG 2367
Query: 889 G-----------FQRDA-------FGRGCI----DVNECWASPGRLCQHTCENTLGSYRC 926
G FQ GRG + D++EC C N GSY C
Sbjct: 2368 GRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHC 2427
Query: 927 SCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDID 984
C +G+ G C D+NEC + C+ C N GSYQC C +GY L EDG +C D+D
Sbjct: 2428 ICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
Query: 985 ECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHN 1044
ECA C F C+N G + C CP G+T + SC D +EC + C C N
Sbjct: 2488 ECATKQHN-CQFLCVNTIGGFTCKCPP-GFTQ--HHTSCIDNNECTSDINLCGSKGICQN 2543
Query: 1045 IQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
GSF C EC + + +T ++C D EC+ +
Sbjct: 2544 TPGSFTC---ECQRGF-SLDQT---GSSCEDVDECEGN 2574
Score = 216 bits (550), Expect = 1e-55
Identities = 188/665 (28%), Positives = 272/665 (40%), Gaps = 118/665 (17%)
Query: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEP----LIVP 562
++ G+ + K C CC LG +A G CE P + ++ EG P +I+
Sbjct: 1550 SNEIGVGVSKASC-CCSLG---KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
Query: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAEL-PNSLPGDDQDECLLLPGELCQHLCI 621
++ E + G T L ++ DD +EC PG C
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPGTCY 1664
Query: 622 NTVGSYHCACFPGF-------------------SLQDDGRTCRPE--------------- 647
NTVG+Y C C P + + D +TC E
Sbjct: 1665 NTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYN 1724
Query: 648 -GHPPQPEAPQEPALKS-EFSQVASNTIP---------LPLPQPNTCKDNGPCKQ-VCST 695
G Q P + EF+ + + P LP+ + G C+ VC
Sbjct: 1725 IGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCIN 1784
Query: 696 VGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 755
+ GS C C G+ + CEDI+EC C R C+NT GS+ C C+PGY
Sbjct: 1785 MVGSFRCECPVGFFYNDKLLVCEDIDECQNG-PVCQRNAECINTAGSYRC----DCKPGY 1839
Query: 756 ALKD-GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINE 813
G+C D +EC + C G C +T GSFYC C GF D + C+DINE
Sbjct: 1840 RFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYCL----CHTGFKTNDDQTMCLDINE 1894
Query: 814 CTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV-HRCGEG 872
C + C G +C NT+GS+ C+ C G+ S + C+DV+EC +G + C G
Sbjct: 1895 CER--DACGNG-TCRNTIGSFNCR-----CNHGFILSHNND-CIDVDECASGNGNLCRNG 1945
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
Q C N GS++C C G++ GR C+D+NEC P + TC+N GSYRC C G+
Sbjct: 1946 Q-CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGY 2004
Query: 933 LLAADGKRCEDVNEC--EAQRCS-QECANIYGSYQCYCRQGYQLAEDGHTCTDI------ 983
L ++CED++EC E + C+ C+N GS++C C +G+ L+ G C D+
Sbjct: 2005 SL--QNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCY 2062
Query: 984 ------------------DEC-----AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
EC +G G C +++ CP +
Sbjct: 2063 AKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPD 2122
Query: 1021 RSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQ 1080
S D+DEC C + C N GS+RC ECP Y+ + C C
Sbjct: 2123 DSAVDMDECK-EPDVCKHGQ-CINTDGSYRC---ECPFGYILAGNECVDTDECSVGNPCG 2177
Query: 1081 NSPAR 1085
N +
Sbjct: 2178 NGTCK 2182
Score = 201 bits (511), Expect = 3e-51
Identities = 162/579 (27%), Positives = 234/579 (40%), Gaps = 150/579 (25%)
Query: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
G D +EC L P +C N G+Y C C G+ + G+ C
Sbjct: 721 GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC----------------- 763
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
+ ++ N++ C DNG C+ GS +C+C G+ D +CEDI+
Sbjct: 764 -VDINECVLNSL--------LC-DNGQCR----NTPGSFVCTCPKGFIYKPDLKTCEDID 809
Query: 722 ECVTDLHTCSRGEHCVNTLGSF--HCYKALTCEP-------------GYALKDGECE--- 763
EC + C G C N+ GSF C T +P + DG CE
Sbjct: 810 EC--ESSPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEINI 866
Query: 764 -------------------------------------------DVDECAMGTHTCQPGFL 780
D+DEC + C+ G L
Sbjct: 867 NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNG-L 925
Query: 781 CQNTKGSFYCQARQRCMDGFLQDPEGN-CVDI-----------NECTSLSEPCRPGFSCI 828
C NT+GSF CQ C G D G C+DI ECT +C
Sbjct: 926 CVNTRGSFKCQ----CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACC 981
Query: 829 NTV----GSYTCQRNPL--------ICARG-----YHASDDGTKCVDVNECETGVHRCGE 871
+V G+ C+ P+ +C RG ++ D+NEC+ C
Sbjct: 982 CSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTH 1041
Query: 872 GQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC--- 928
G+ C N GS++C C +GF D+ R C D++EC SP + C NT G + C C
Sbjct: 1042 GK-CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEG 1100
Query: 929 -ASGFLLAADGKRCEDVNECEAQRC---SQECANIYGSYQCYCRQGYQLAEDGHTCTDID 984
SGF++ K C D++EC+ C N GSY+C C G+QL+ + C DI+
Sbjct: 1101 YESGFMMM---KNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDIN 1157
Query: 985 ECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHN 1044
EC A + RC+N+ G YQCAC GY T + C D+DEC++ C C N
Sbjct: 1158 ECELSAHLCPNGRCVNLIGKYQCAC-NPGYHSTPDRLFCVDIDECSIMNGGCE--TFCTN 1214
Query: 1045 IQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
+GS+ C C P + + ++ +C D EC+++P
Sbjct: 1215 SEGSYEC---SCQPGFALMP----DQRSCTDIDECEDNP 1246
Score = 201 bits (511), Expect = 3e-51
Identities = 121/338 (35%), Positives = 151/338 (44%), Gaps = 54/338 (15%)
Query: 602 GDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
G D DEC ++ C+N GSYHC C G++ G +C E Q P
Sbjct: 2400 GADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-----VDLNECNQAPK- 2453
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
PC +C GS CSC GY + DG SC+D++
Sbjct: 2454 --------------------------PCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLD 2487
Query: 722 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLC 781
EC T H C CVNT+G F C C PG+ C D +EC + C +C
Sbjct: 2488 ECATKQHNCQ--FLCVNTIGGFTC----KCPPGFTQHHTSCIDNNECTSDINLCGSKGIC 2541
Query: 782 QNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
QNT GSF C+ C GF D G +C D++EC + C+ G C N +G Y C
Sbjct: 2542 QNTPGSFTCE----CQRGFSLDQTGSSCEDVDECEG-NHRCQHG--CQNIIGGYRCS--- 2591
Query: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
C +GY +CVD NEC H CG G CHN GSY+C C AGFQ + F GC
Sbjct: 2592 --CPQGYLQHYQWNQCVDENEC-LSAHICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 938
D+NEC S C + C NT G Y C C G+ G
Sbjct: 2648 DINEC-GSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQG 2684
Score = 199 bits (506), Expect = 1e-50
Identities = 153/471 (32%), Positives = 212/471 (45%), Gaps = 83/471 (17%)
Query: 646 PEGHPPQPEAP-QEPALKSEFSQVASNTIPLPLPQPNTCK------DNGPCKQVCSTVGG 698
P G PP P+ P P ++ + + LP+ + C+ NG C G
Sbjct: 416 PPGFPPGPQIPVPRPPVEYLYPSREPPRV-LPVNVTDYCQLVRYLCQNGRC----IPTPG 470
Query: 699 SAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY--A 756
S C C G+ + G C D++EC + + C+ GE C+N GS+ C C GY
Sbjct: 471 SCRCECNKGFQLDLRG-ECIDVDEC--EKNPCAGGE-CINNQGSYTCQ----CRAGYQST 522
Query: 757 LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECT 815
L EC D+DEC C G C NT GSF+C C GF +G NC D++EC
Sbjct: 523 LTRTECRDIDECLQNGRICNNG-RCINTDGSFHCV----CNAGFHVTRDGKNCEDMDEC- 576
Query: 816 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET-GVHRCGEGQV 874
S+ C G CIN GS+ C IC G+ + DG C D+NECET G+ C G+
Sbjct: 577 SIRNMCLNGM-CINEDGSFKC-----ICKPGFQLASDGRYCKDINECETPGI--CMNGR- 627
Query: 875 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNE--------------------------CWAS 908
C N GSYRC+C G GR C+D + C AS
Sbjct: 628 CVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
Query: 909 P----GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQE-CANIYG 961
G CQ Y+ C+SG + + G D+NEC + C C N+ G
Sbjct: 688 TEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDICPNGICENLRG 744
Query: 962 SYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR 1021
+Y+C C GY++ G C DI+EC + + +C N PGS+ C CP +G+ + +
Sbjct: 745 TYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCP-KGFIYKPDLK 803
Query: 1022 SCKDVDECALGTHNCSEAETCHNIQGSFRCLRFEC-PPNYVQVSKTKCERT 1071
+C+D+DEC + C C N GSF C EC + + +KT C T
Sbjct: 804 TCEDIDECE--SSPCING-VCKNSPGSFIC---ECSSESTLDPTKTICIET 848
Score = 195 bits (495), Expect = 2e-49
Identities = 210/773 (27%), Positives = 284/773 (36%), Gaps = 156/773 (20%)
Query: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
AW P P +P +P+ D + +IP G+ T E C A
Sbjct: 216 AWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPA 275
Query: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETC------ 502
G + + +C +I E T +C + VS K C G + +G C
Sbjct: 276 GHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCK-CPPGFYTSPDGTRCIDVRPG 334
Query: 503 ---GAEDNDSCG------ISLYKQCCD---CCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
A N C I+ + CCD C G+ V E + + C+ M+
Sbjct: 335 YCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMV 394
Query: 551 SCCEGEEP----------LIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSL 600
E P L VP P PR E RE P L
Sbjct: 395 IPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREP---------PRVL 445
Query: 601 PGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP 659
P + D C L+ LCQ+ CI T GS C C GF L
Sbjct: 446 PVNVTDYCQLVR-YLCQNGRCIPTPGSCRCECNKGFQLD--------------------- 483
Query: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCED 719
L+ E V + C+ N C GS C C GY C D
Sbjct: 484 -LRGECIDV------------DECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRD 530
Query: 720 INECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQP 777
I+EC+ + C+ G C+NT GSFHC C G+ +DG+ CED+DEC++ + C
Sbjct: 531 IDECLQNGRICNNG-RCINTDGSFHC----VCNAGFHVTRDGKNCEDMDECSI-RNMCLN 584
Query: 778 GFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTC 836
G +C N GSF C C GF +G C DINEC + C G C+NT GSY C
Sbjct: 585 G-MCINEDGSFKC----ICKPGFQLASDGRYCKDINECET-PGICMNG-RCVNTDGSYRC 637
Query: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSY-RCDCKAGFQRDAF 895
+ C G DG CVD + T GQ L G+ + +C AF
Sbjct: 638 E-----CFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAF 692
Query: 896 GRGC-------------------------IDVNECWASPGRLCQHTCENTLGSYRCSCAS 930
G C D+NEC P CEN G+Y+C C S
Sbjct: 693 GEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNS 752
Query: 931 GFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECA 987
G+ + + GK C D+NEC + C +C N GS+ C C +G+ D TC DIDEC
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 988 QGAGILCTFRCLNVPGSYQCACPEQG-----------------YTMTANGRSCKDVDECA 1030
I C N PGS+ C C + + +GR +++
Sbjct: 813 SSPCI--NGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGAT 870
Query: 1031 LGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
L + CS + + C Y ++ T+CE D EC+ P
Sbjct: 871 LKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE-----DIDECEVFP 918
Score = 177 bits (450), Expect = 4e-44
Identities = 165/617 (26%), Positives = 222/617 (35%), Gaps = 155/617 (25%)
Query: 594 AELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQP 653
A +P+ D DEC P C N G Y C C+ GF +D +TC
Sbjct: 1228 ALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----- 1282
Query: 654 EAPQEPAL-------KSEFSQVASNTIPLPLPQPNT-CKDNGPCK---------QVCSTV 696
E P + ++ S + + + T C D C+ VC+
Sbjct: 1283 ECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNT 1342
Query: 697 GGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA 756
GS CSC PG+ + DG+ C D++EC H CS+ C NT+GS+ C C+ GY
Sbjct: 1343 AGSFKCSCSPGW--IGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL----CKEGYT 1396
Query: 757 LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA------------------------ 792
C D+DEC+ + C G C N G + C+
Sbjct: 1397 GDGFTCTDLDECSENLNLCGNG-QCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNI 1455
Query: 793 -------------RQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQR 838
R C G+ D G NC D+NEC + C G +C+NT GSY C
Sbjct: 1456 CVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTT-CISG-NCVNTPGSYICD- 1512
Query: 839 NPLICARGYHASDDGTKCVDV---------------------NECETGVHR----CGEGQ 873
C + + CVD NE GV + C G+
Sbjct: 1513 ----CPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGK 1568
Query: 874 V----CHNLPG----SYRCDCKAG--FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLG 922
C P Y+ C G F+ + D++EC PG LCQ C NT G
Sbjct: 1569 AWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG-LCQGGKCINTFG 1627
Query: 923 SYRCSCASGFLLAADGKRCEDVNECEAQR-CSQ-ECANIYGSYQCYCRQGYQLAEDGHTC 980
S++C C +G+ L D + C+DVNECE C C N G+Y C C Y G+ C
Sbjct: 1628 SFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC 1687
Query: 981 TDIDE----------------------------CAQGAGILCTFRCLNVP------GSYQ 1006
D+ C+ G C P +
Sbjct: 1688 MDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATL 1747
Query: 1007 CACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKT 1066
C G+ + D+DEC C E C N+ GSFRC ECP + K
Sbjct: 1748 CGSQRPGFVIDIYTGLPVDIDECREIPGVC-ENGVCINMVGSFRC---ECPVGFFYNDKL 1803
Query: 1067 KCERTTCHDFLECQNSP 1083
C D ECQN P
Sbjct: 1804 ----LVCEDIDECQNGP 1816
Score = 94.0 bits (232), Expect = 8e-19
Identities = 85/307 (27%), Positives = 117/307 (38%), Gaps = 54/307 (17%)
Query: 679 QPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVN 738
+PN C P Q+ + G +I C + C + C D C +G
Sbjct: 96 RPNMC--TCPSGQIAPSCGSRSIQHC---------NIRCMNGGSCSDDHCLCQKGY---- 140
Query: 739 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFL---CQN---TKGSFYCQA 792
+G+ HC + + CE G L G C + CA C GF C+ T F +
Sbjct: 141 -IGT-HCGQPV-CESG-CLNGGRCVAPNRCA-----CTYGFTGPQCERDYRTGPCFTVIS 191
Query: 793 RQRC---MDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA 849
Q C + G + C + + PC C P C RG+
Sbjct: 192 NQMCQGQLSGIVCTKTLCCATVGR--AWGHPCE------------MCPAQPHPCRRGFIP 237
Query: 850 SDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASP 909
+ C DV+EC+ C +G C N GS+ C C AG + + + C D++EC P
Sbjct: 238 NIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIP 296
Query: 910 GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE--CEAQ----RCSQECANIYGSY 963
G C NT+ SY C C GF + DG RC DV C RCS +
Sbjct: 297 GICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKM 356
Query: 964 QCYCRQG 970
QC C G
Sbjct: 357 QCCCDAG 363
Score = 89.0 bits (219), Expect = 2e-17
Identities = 86/268 (32%), Positives = 102/268 (38%), Gaps = 56/268 (20%)
Query: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
R C DGF P N CT S P SC GS + Q + C G SDD
Sbjct: 86 RHSCGDGFCSRP-------NMCTCPSGQIAP--SC----GSRSIQHCNIRCMNGGSCSDD 132
Query: 853 ---------GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF-----QRDAFGRG 898
GT C CE+G C G C RC C GF +RD
Sbjct: 133 HCLCQKGYIGTHCGQP-VCESG---CLNGGRC---VAPNRCACTYGFTGPQCERDYRTGP 185
Query: 899 CIDVNE-----------------CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRC 941
C V C A+ GR H CE C GF+ C
Sbjct: 186 CFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGAC 244
Query: 942 EDVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 998
+DV+EC+A C C N GS++C C G++L E C DIDEC+ GI C
Sbjct: 245 QDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
Query: 999 LNVPGSYQCACPEQGYTMTANGRSCKDV 1026
N SY C CP YT + +G C DV
Sbjct: 305 TNTVSSYFCKCPPGFYT-SPDGTRCIDV 331
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 280 bits (715), Expect = 8e-75
Identities = 172/523 (32%), Positives = 247/523 (47%), Gaps = 73/523 (13%)
Query: 683 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C PC C G+ CSC G I ADG +C+DI+EC HTC G+ C NT+GS
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGS 5170
Query: 743 FHCYKALTCEPGY-ALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
+ C + C G+ DG C+D++EC + Q C N GSF+C C G+
Sbjct: 5171 YRC--VVRCGSGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHC----GCEPGY 5221
Query: 801 LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVN 860
Q C+D+NEC CRP C NT G Y C +C G +++GT C+D++
Sbjct: 5222 -QLKGRKCMDVNECR--QNVCRPDQHCKNTRGGYKCID---LCPNGMTKAENGT-CIDID 5274
Query: 861 ECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENT 920
EC+ G H+C Q+C N GSYRC C G++ GR C+D+NEC P + C H C NT
Sbjct: 5275 ECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVP-KPCAHQCSNT 5333
Query: 921 LGSYRCSCASGFLLAADGKRCEDV----------------------NECEAQRCSQECAN 958
GS++C C G L DGK C + N + Q+ ++ ++
Sbjct: 5334 PGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSH 5393
Query: 959 IYGSYQCY-----------------CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNV 1001
+Y SY Y C +G + + D TC DIDEC C C N
Sbjct: 5394 LYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECENTDA--CQHECKNT 5449
Query: 1002 PGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061
GSYQC CP GY +T NG++C+D+DEC +C C N++GS++C+ CPPNY
Sbjct: 5450 FGSYQCICP-PGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQ 5508
Query: 1062 QVSKTK-CERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTI--- 1117
+ + C + + LEC SP + + ++ G+ + R+ A+T D +
Sbjct: 5509 RDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRL---VAYTQDGVMHP 5565
Query: 1118 --ALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDV 1158
++ + F R N GVVY R + E + + V
Sbjct: 5566 RTTFLMVDEEQTVPFALRDEN-LKGVVYTTRPLREAETYRMRV 5607
Score = 195 bits (495), Expect = 2e-49
Identities = 136/434 (31%), Positives = 185/434 (42%), Gaps = 97/434 (22%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-- 661
D+DEC G C H C N +G+Y+C+C G ++ DGRTC+ E AL
Sbjct: 5107 DEDECAA--GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDI---------DECALGR 5155
Query: 662 -KSEFSQVASNTIP------------------LPLPQPNTCKDNGPCKQVCSTVGGSAIC 702
Q NTI L N C+++ PC Q C GS C
Sbjct: 5156 HTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHC 5215
Query: 703 SCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGE 761
C PGY + G C D+NEC ++ C +HC NT G + C C G ++G
Sbjct: 5216 GCEPGYQL--KGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCID--LCPNGMTKAENGT 5269
Query: 762 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEP 820
C D+DEC GTH C+ +C+NT+GS+ C C G+ G C+DINEC + +P
Sbjct: 5270 CIDIDECKDGTHQCRYNQICENTRGSYRCV----CPRGYRSQGVGRPCMDINECEQVPKP 5325
Query: 821 CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH---- 876
C C NT GS+ C IC G H DG C + + +
Sbjct: 5326 C--AHQCSNTPGSFKC-----ICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPV 5378
Query: 877 --------------NLPGSY-----------------RCDCKAGFQRDAFGRGCIDVNEC 905
+L SY R C G +A C+D++EC
Sbjct: 5379 RNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG--SEASHDTCVDIDEC 5436
Query: 906 WASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC----SQECANIYG 961
+ CQH C+NT GSY+C C G+ L +GK C+D++EC Q ++ C N+ G
Sbjct: 5437 ENTDA--CQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRG 5494
Query: 962 SYQCY---CRQGYQ 972
SYQC C YQ
Sbjct: 5495 SYQCIDTPCPPNYQ 5508
Score = 171 bits (434), Expect = 3e-42
Identities = 101/256 (39%), Positives = 129/256 (50%), Gaps = 29/256 (11%)
Query: 843 CARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV 902
C G+ G C D +EC G + C CHN G+Y C C G A GR C D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 903 NECWASPGRLCQHT---CENTLGSYRC--SCASGFLLAADGKRCEDVNEC-EAQRCSQEC 956
+EC + GR H C+NT+GSYRC C SGF +DG C+D+NEC E+ C Q C
Sbjct: 5149 DEC--ALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRC 5206
Query: 957 ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC--TFRCLNVPGSYQC--ACPEQ 1012
N GS+ C C GYQL G C D++EC Q +C C N G Y+C CP
Sbjct: 5207 FNAIGSFHCGCEPGYQL--KGRKCMDVNECRQN---VCRPDQHCKNTRGGYKCIDLCP-N 5260
Query: 1013 GYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTT 1072
G T NG +C D+DEC GTH C + C N +GS+RC+ CP Y +++
Sbjct: 5261 GMTKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCV---CPRGY----RSQGVGRP 5312
Query: 1073 CHDFLECQNSPARITH 1088
C D EC+ P H
Sbjct: 5313 CMDINECEQVPKPCAH 5328
Score = 150 bits (378), Expect = 9e-36
Identities = 80/212 (37%), Positives = 112/212 (52%), Gaps = 21/212 (9%)
Query: 886 CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 945
C +GF D+ G C D +EC A G C H+C N +G+Y CSC G +AADG+ C+D++
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAA--GNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 946 ECEAQR----CSQECANIYGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCL 999
EC R Q+C N GSY+C C G++ DG +C DI+EC + + C RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRCF 5207
Query: 1000 NVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1059
N GS+ C C E GY + GR C DV+EC C + C N +G ++C+ CP
Sbjct: 5208 NAIGSFHCGC-EPGYQL--KGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDL-CPN- 5260
Query: 1060 YVQVSKTKCERTTCHDFLECQNSPARITHYQL 1091
TK E TC D EC++ + + Q+
Sbjct: 5261 ----GMTKAENGTCIDIDECKDGTHQCRYNQI 5288
Score = 89.0 bits (219), Expect = 2e-17
Identities = 116/475 (24%), Positives = 158/475 (33%), Gaps = 133/475 (28%)
Query: 434 PEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGV 493
P G T D + CA D DEC N C + + +Y SC G+
Sbjct: 5093 PSGFTLDSVGPFCA-------DEDEC-------AAGNPCSHSCHNAMGTYYC--SCPKGL 5136
Query: 494 LGAKEGETCGAEDNDSCGISLYK----QCCD-------C---CGLGLRVRAEGQSCE--S 537
A +G TC +D D C + + Q CD C CG G R ++G SC+ +
Sbjct: 5137 TIAADGRTC--QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDIN 5194
Query: 538 NPNLGYPCNHVMLSC-------CE------GEEPLIVPEVRRPPEPAAAPRRVSEAEMAG 584
PC+ + CE G + + V E R + P + + G
Sbjct: 5195 ECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECR---QNVCRPDQHCKNTRGG 5251
Query: 585 REALSLGTEAELPNSLPGDDQDECLLLP-----GELCQH--LCINTVGSYHCACFPGFSL 637
+ + L PN + + C+ + C++ +C NT GSY C C G+
Sbjct: 5252 YKCIDL-----CPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS 5306
Query: 638 QDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVG 697
Q GR C E Q P PC CS
Sbjct: 5307 QGVGRPCMDIN-----ECEQVPK---------------------------PCAHQCSNTP 5334
Query: 698 GSAICSCFPGYAIMADGVSCEDINECVT-----DLHTCSRGEHCVNTLGSFHCYKAL--- 749
GS C C PG ++ DG SC + + +R N Y+
Sbjct: 5335 GSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHL 5394
Query: 750 -----------------------TCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKG 786
TC G C D+DEC T CQ C+NT G
Sbjct: 5395 YSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE-NTDACQ--HECKNTFG 5451
Query: 787 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
S+ C C G+ G C DI+EC + C P C N GSY C P
Sbjct: 5452 SYQC----ICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTP 5502
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 266 bits (681), Expect = 7e-71
Identities = 216/692 (31%), Positives = 283/692 (40%), Gaps = 113/692 (16%)
Query: 454 IDNDECLEIPESGTEDNVCR-TAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGI 512
ID DECL + ++ +CR T + C +C G + E ETC ED + C
Sbjct: 809 IDIDECL-VNRLLCDNGLCRNTPGSYSC-------TCPPGYVFRTETETC--EDINEC-- 856
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCE---GEEPLIVPEVRRPPE 569
+ C R +CE +P G + L C + G L + + R
Sbjct: 857 ----ESNPCVNGACRNNLGSFNCECSP--GSKLSSTGLICIDSLKGTCWLNIQDSRCEVN 910
Query: 570 PAAAPRRVSEAEMAGREALSLGTEAELPNSLPG----------DDQDECLLLPGELCQHL 619
A + G S EL + P +D +EC + PG
Sbjct: 911 INGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGR 970
Query: 620 CINTVGSYHCACFPGFSLQDDGRTC-------------RPEGHPPQPEAPQEPALKSEFS 666
C+N+ GS+HC C G +L GR C E P P + A
Sbjct: 971 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
Query: 667 QVASNTIPLPLPQPNT-------------------------CKDNGPCKQV--------C 693
A T P+P T KD CK C
Sbjct: 1031 -AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKC 1089
Query: 694 STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEP 753
GS C C G+A+ + +C DI+EC C G CVNT GSF C E
Sbjct: 1090 RNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGI-CVNTPGSFECECFEGYES 1148
Query: 754 GYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDIN 812
G+ + C D+DEC C+ G C NT+GSF C C G P +CVDIN
Sbjct: 1149 GFMMMKN-CMDIDECERNPLLCRGG-TCVNTEGSFQCD----CPLGHELSPSREDCVDIN 1202
Query: 813 ECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEG 872
EC+ CR G C+N +G+Y C NP GY A+ D C D++EC + G
Sbjct: 1203 ECSLSDNLCRNG-KCVNMIGTYQCSCNP-----GYQATPDRQGCTDIDECM--IMNGGCD 1254
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
C N GSY C C G+ GR C D++EC +P C N G YRC C GF
Sbjct: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGF 1314
Query: 933 LLAADGKRCEDVNECEAQR---CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 989
+ + D K C DVNEC+ EC N GS+ C+C+ GY + + CTD+DEC G
Sbjct: 1315 MASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIG 1374
Query: 990 AGILCTFR--CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQG 1047
A C CLN+PGS++C+C E NG C D+DEC+ GTH CS C N G
Sbjct: 1375 AH-NCDMHASCLNIPGSFKCSCRE---GWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1430
Query: 1048 SFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
S+RC C + + TC D EC
Sbjct: 1431 SYRC---ACSEGFTG------DGFTCSDVDEC 1453
Score = 266 bits (679), Expect = 1e-70
Identities = 196/627 (31%), Positives = 270/627 (43%), Gaps = 111/627 (17%)
Query: 445 CCAAGQQWAIDNDECLEIPESGTED---------------------------NVCRTAQR 477
CCA G W + +EC P+ GT++ N C+
Sbjct: 1026 CCAVGAAWGTECEEC---PKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG 1082
Query: 478 HC----CVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
C C + + C A + E D D C IS D CG G+ V G
Sbjct: 1083 MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISP-----DLCGSGICVNTPG- 1136
Query: 534 SCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTE 593
S E GY +M+ C + + E R P V+ E + + LG E
Sbjct: 1137 SFECECFEGYESGFMMMKNC-----MDIDECERNPLLCRGGTCVN-TEGSFQCDCPLGHE 1190
Query: 594 AELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQ 652
P+ D +EC L LC++ C+N +G+Y C+C PG+ D + C
Sbjct: 1191 LS-PSREDCVDINECSL-SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-------- 1240
Query: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
+ + I NG C C+ GS CSC GYA+M
Sbjct: 1241 -------------TDIDECMIM-----------NGGCDTQCTNSEGSYECSCSEGYALMP 1276
Query: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY--ALKDGECEDVDECAM 770
DG SC DI+EC + C G+ C N G + C C G+ ++ C DV+EC +
Sbjct: 1277 DGRSCADIDECENNPDICDGGQ-CTNIPGEYRC----LCYDGFMASMDMKTCIDVNECDL 1331
Query: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCIN 829
++ C G C+NTKGSF C C G+ ++ C D++EC + C SC+N
Sbjct: 1332 NSNICMFG-ECENTKGSFIC----HCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1386
Query: 830 TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 889
GS+ C C G+ +G KC+D++EC G H+C C N PGSYRC C G
Sbjct: 1387 IPGSFKCS-----CREGW--IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEG 1439
Query: 890 FQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
F D F C DV+EC A LC++ C N G+YRC C GF A+D + C+D++EC
Sbjct: 1440 FTGDGF--TCSDVDEC-AENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS 1496
Query: 949 AQRCS--QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQ 1006
Q C N+ G + C C GY+L G CTDIDECA + C+N PG Y+
Sbjct: 1497 FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCV-NGLCVNTPGRYE 1555
Query: 1007 CACPEQGYTMTANGRSCKD--VDECAL 1031
C CP + + G C D V C L
Sbjct: 1556 CNCPPD-FQLNPTGVGCVDNRVGNCYL 1581
Score = 263 bits (672), Expect = 7e-70
Identities = 175/540 (32%), Positives = 244/540 (45%), Gaps = 56/540 (10%)
Query: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
N G+ + + C CC LG +A G CE+ P + + + EG P + +
Sbjct: 1594 NTEIGVGVSRSSC-CCSLG---KAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILE 1649
Query: 567 PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD-----DQDECLLLPGELCQHLCI 621
+ + + S E L D D DEC PG C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
Query: 622 NTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPN 681
NT+G+Y C C P + + G C + + +S N +P + +
Sbjct: 1710 NTLGNYTCICPPEYMQVNGGHNCM--------DMRKSFCYRSYNGTTCENELPFNVTKRM 1761
Query: 682 TCKD-------NGPCKQVCSTVGGS---AICSCFPGYAIMADGVSCEDINECVTDLHTCS 731
C N PC + C T G + IC PG+ DI+EC C+
Sbjct: 1762 CCCTYNVGKAWNKPC-EPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA 1820
Query: 732 RGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
G C+N +GSF C C G++ D CED+DEC+ G + CQ C N+ GS+
Sbjct: 1821 NGV-CINQIGSFRC----ECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
Query: 790 CQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHA 849
C+ C GF P G CVD NEC + C G C++ GSY C IC G+ A
Sbjct: 1876 CE----CAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQC-----ICHNGFKA 1925
Query: 850 SDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASP 909
S D T C+DV+ECE H CG G C N GSY C C GF+ C+D++EC +
Sbjct: 1926 SQDQTMCMDVDECER--HPCGNG-TCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFF 1981
Query: 910 GRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQ-ECANIYGSYQC 965
G++C++ C N +GS++C C G+ L DGK C D NEC A CS C N+ GS++C
Sbjct: 1982 GQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRC 2041
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
C GY++ + C DI+EC + I C N PG +QC CP G+ ++ NGR C D
Sbjct: 2042 ICPPGYEVKSE--NCIDINECDEDPNICLFGSCTNTPGGFQCLCP-PGFVLSDNGRRCFD 2098
Score = 255 bits (651), Expect = 2e-67
Identities = 177/522 (33%), Positives = 240/522 (45%), Gaps = 68/522 (13%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
+D +ECL PG CINT GS+ C C G++L G C
Sbjct: 2170 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2229
Query: 663 SEFSQVASNTIPLPLPQPN-TCKDNGPCKQV-------CSTVGGSAICSCFPGYAIMADG 714
+ N P P C+D C Q C GS C+C GYA+ D
Sbjct: 2230 NVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 2289
Query: 715 VSCEDINECVTDLHTC-SRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMG 771
C+D++EC LH C SRG C N +G+F C C PG A + DGE C D +EC
Sbjct: 2290 KMCKDLDECAEGLHDCESRGMMCKNLIGTFMC----ICPPGMARRPDGEGCVDENECRTK 2345
Query: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEP----CRPGFS 826
C+ G C N GS+ C+ C +GF G C+D + +E C+ S
Sbjct: 2346 PGICENG-RCVNIIGSYRCE----CNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASS 2400
Query: 827 CINTV------------GSYTCQRNPL--------ICARGYHASDDGTKCVDVNECETGV 866
N V + C+ PL IC G + DG D++EC+
Sbjct: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKVMP 2457
Query: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC 926
+ C GQ C N GS+RC CK G+ D G CID++EC SP + C + C+NT GSY+C
Sbjct: 2458 NLCTNGQ-CINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP-KPCNYICKNTEGSYQC 2515
Query: 927 SCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDID 984
SC G++L DGK C+D++EC+ ++ C C N G + C C G+ + C D +
Sbjct: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGF--TQHHTACIDNN 2573
Query: 985 ECAQGAGILCTFR--CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETC 1042
EC LC + C N PGS+ C C ++G+++ A G +C+DVDEC G H C C
Sbjct: 2574 ECGSQPS-LCGAKGICQNTPGSFSCEC-QRGFSLDATGLNCEDVDECD-GNHRCQHG--C 2628
Query: 1043 HNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPA 1084
NI G +RC CP Y+Q + C D EC N A
Sbjct: 2629 QNILGGYRC---GCPQGYIQ----HYQWNQCVDENECSNPNA 2663
Score = 246 bits (628), Expect = 9e-65
Identities = 175/585 (29%), Positives = 255/585 (43%), Gaps = 80/585 (13%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D++EC PG C+N +GSY C C GF G C + +
Sbjct: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR-----QGLCFAEVLQ 2392
Query: 664 EFSQVASNTIPLPLPQPNTCKDNG-----PCKQVCSTVGGSA---ICSCFPGYAIMADGV 715
Q+AS++ L + + C D G C ++C G + IC PGY DG
Sbjct: 2393 TICQMASSSRNL-VTKSECCCDGGRGWGHQC-ELCPLPGTAQYKKICPHGPGYT--TDG- 2447
Query: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDGECEDVDECAMGTH 773
DI+EC + C+ G+ C+NT+GSF C+ C+ GY + C D+DEC+
Sbjct: 2448 --RDIDECKVMPNLCTNGQ-CINTMGSFRCF----CKVGYTTDISGTSCIDLDECSQSPK 2500
Query: 774 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVG 832
C ++C+NT+GS+ C C G++ +G C D++EC + C+ F C+NT+G
Sbjct: 2501 PCN--YICKNTEGSYQCS----CPRGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNTLG 2552
Query: 833 SYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQR 892
+TC+ C G+ + T C+D NEC + CG +C N PGS+ C+C+ GF
Sbjct: 2553 GFTCK-----CPPGF--TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSL 2605
Query: 893 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 952
DA G C DV+EC CQH C+N LG YRC C G++ +C D NEC
Sbjct: 2606 DATGLNCEDVDEC--DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA 2663
Query: 953 --SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP 1010
S C N GSY+C C G+ + C D++EC+ C + C N G Y C CP
Sbjct: 2664 CGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKN-PCNYGCSNTEGGYLCGCP 2722
Query: 1011 EQGYTMTANGRSCKDV---------------DECALGTHNCSEAETCHNIQGSFRCLRFE 1055
GY G + +E AL C E + + R R
Sbjct: 2723 -PGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGYSKKDSRQKRSI 2781
Query: 1056 CPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGD 1115
P+ V + E D N ++H L HI + PA +
Sbjct: 2782 HEPDPTAVEQISLESV---DMDSPVNMKFNLSH--------LGSKEHILELRPAIQPLNN 2830
Query: 1116 TIALNIIKGNEEGYFGTRRLNAYTGVVYLQRA--VLEPRDFALDV 1158
I I +GN++ F R++ G+ YL A L P + L++
Sbjct: 2831 HIRYVISQGNDDSVF---RIHQRNGLSYLHTAKKKLMPGTYTLEI 2872
Score = 241 bits (616), Expect = 2e-63
Identities = 168/540 (31%), Positives = 230/540 (42%), Gaps = 132/540 (24%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
+D +EC P LC C+NT GSY C C G++L++D + C+
Sbjct: 2252 EDINECAQNP-LLCAFRCMNTFGSYECTCPIGYALREDQKMCK----------------- 2293
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINE 722
+ + A + C+ G +C + G+ +C C PG A DG C D NE
Sbjct: 2294 -DLDECAEGL--------HDCESRG---MMCKNLIGTFMCICPPGMARRPDGEGCVDENE 2341
Query: 723 CVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDE-------------CA 769
C T C G CVN +GS+ C C G+ E +D C
Sbjct: 2342 CRTKPGICENG-RCVNIIGSYRC----ECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQ 2396
Query: 770 MGT--------------------HTCQ-----------------PGF------------- 779
M + H C+ PG+
Sbjct: 2397 MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVM 2456
Query: 780 --LCQN-----TKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTV 831
LC N T GSF C C G+ D G +C+D++EC+ +PC + C NT
Sbjct: 2457 PNLCTNGQCINTMGSFRC----FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTE 2510
Query: 832 GSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQ 891
GSY C C RGY +DG C D++EC+T H C +C N G + C C GF
Sbjct: 2511 GSYQCS-----CPRGYVLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTCKCPPGFT 2563
Query: 892 RDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA 949
+ CID NEC + P LC + C+NT GS+ C C GF L A G CEDV+EC+
Sbjct: 2564 Q--HHTACIDNNECGSQPS-LCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG 2620
Query: 950 -QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1008
RC C NI G Y+C C QGY + C D +EC+ + C N GSY+CA
Sbjct: 2621 NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCA 2679
Query: 1009 CPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1068
CP G++ +C DV+EC+ + C+ C N +G + C CPP Y +V + C
Sbjct: 2680 CP-SGFSFDQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLC---GCPPGYYRVGQGHC 2733
Score = 235 bits (600), Expect = 2e-61
Identities = 165/517 (31%), Positives = 225/517 (43%), Gaps = 100/517 (19%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC +PG +CIN +GS+ C C GFS D C
Sbjct: 1808 DIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC------------------- 1848
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
E SN N C+ N C GS C C G+ + +G +C D NEC
Sbjct: 1849 EDIDECSNG-------DNLCQRNADC----INSPGSYRCECAAGFKLSPNG-ACVDRNEC 1896
Query: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLC 781
+ + CS G CV+ GS+ C C G+ + C DVDEC H C G C
Sbjct: 1897 LEIPNVCSHGL-CVDLQGSYQCI----CHNGFKASQDQTMCMDVDECER--HPCGNG-TC 1948
Query: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSL-SEPCRPGFSCINTVGSYTCQRNP 840
+NT GS+ C C GF +C+DI+EC+S + CR G C N +GS+ C
Sbjct: 1949 KNTVGSYNCL----CYPGFELTHNNDCLDIDECSSFFGQVCRNG-RCFNEIGSFKC---- 1999
Query: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
+C GY + DG C+D NEC C G C NL GS+RC C G++ + CI
Sbjct: 2000 -LCNEGYELTPDGKNCIDTNECVALPGSCSPG-TCQNLEGSFRCICPPGYEVKS--ENCI 2055
Query: 901 DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC------EAQRCSQ 954
D+NEC P +C NT G ++C C GF+L+ +G+RC D + E +CS
Sbjct: 2056 DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSV 2115
Query: 955 E-----------CANIYG----------------SYQCYCRQGYQLAEDGH-TCTDIDEC 986
C+ + G ++Q C G+ H T D++EC
Sbjct: 2116 PKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNEC 2175
Query: 987 AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQ 1046
+ GI +C+N GS++C CP GY + G C D DEC++G + C TC N+
Sbjct: 2176 LESPGICSNGQCINTDGSFRCECP-MGYNLDYTGVRCVDTDECSIG-NPCGNG-TCTNVI 2232
Query: 1047 GSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
GSF C C + CE D EC +P
Sbjct: 2233 GSFEC---NCNEGFEPGPMMNCE-----DINECAQNP 2261
Score = 233 bits (594), Expect = 8e-61
Identities = 189/692 (27%), Positives = 264/692 (38%), Gaps = 165/692 (23%)
Query: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGA 496
+T+ + C G + + ++C++I E DN+CR + CV+ + C
Sbjct: 1176 NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGK---CVNMIGTYQCSCNPGYQ 1232
Query: 497 KEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGE 556
+ G D D C I + C C +N Y C SC EG
Sbjct: 1233 ATPDRQGCTDIDECMI-MNGGCDTQC--------------TNSEGSYEC-----SCSEGY 1272
Query: 557 EPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELC 616
++P+ GR + E N+ D +C +PGE
Sbjct: 1273 --ALMPD--------------------GRSCADID---ECENNPDICDGGQCTNIPGE-- 1305
Query: 617 QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLP 676
Y C C+ GF D +TC + N L
Sbjct: 1306 ----------YRCLCYDGFMASMDMKTC-----------------------IDVNECDL- 1331
Query: 677 LPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHC 736
N C C GS IC C GY++ C D++EC H C C
Sbjct: 1332 --NSNICMFG-----ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 1384
Query: 737 VNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRC 796
+N GSF C +C G+ +C D+DEC+ GTH C C NT GS+ C C
Sbjct: 1385 LNIPGSFKC----SCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC----AC 1436
Query: 797 MDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
+GF D C D++EC C G C+N G+Y C+ C G+ + D C
Sbjct: 1437 SEGFTGD-GFTCSDVDECAENINLCENG-QCLNVPGAYRCE-----CEMGFTPASDSRSC 1489
Query: 857 VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT 916
D++EC + + C G C+NLPG + C C G++ D G C D++EC A P
Sbjct: 1490 QDIDEC-SFQNICVFG-TCNNLPGMFHCICDDGYELDRTGGNCTDIDEC-ADPINCVNGL 1546
Query: 917 CENTLGSYRCSCASGFLLAADGKRCED--VNECEAQ---------RCSQECANIYGSYQC 965
C NT G Y C+C F L G C D V C + C+ E C
Sbjct: 1547 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 1606
Query: 966 YCRQGYQLAEDGHTC---------------------------TDIDECAQGAGILCTFRC 998
C G TC DIDEC + G+ C
Sbjct: 1607 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNC 1666
Query: 999 LNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1058
+N GS+QC CP QGY ++ + R C+D+DEC C TC+N G++ C+ CPP
Sbjct: 1667 INTFGSFQCECP-QGYYLSEDTRICEDIDECFAHPGVCGPG-TCYNTLGNYTCI---CPP 1721
Query: 1059 NYVQVS---------KTKCER----TTCHDFL 1077
Y+QV+ K+ C R TTC + L
Sbjct: 1722 EYMQVNGGHNCMDMRKSFCYRSYNGTTCENEL 1753
Score = 204 bits (518), Expect = 5e-52
Identities = 176/586 (30%), Positives = 237/586 (40%), Gaps = 129/586 (22%)
Query: 597 PNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC------------ 644
PN D DEC PG CIN+ GS+ C C PG ++ DGR C
Sbjct: 651 PNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGG 709
Query: 645 ----------------------RPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLP--QP 680
P+ +P P +EF + S+ + + +
Sbjct: 710 IKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDI 769
Query: 681 NTCK-DNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVN 738
N C D C +C + GS C+C GY A G +C DI+EC+ + C G C N
Sbjct: 770 NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGL-CRN 828
Query: 739 TLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR- 795
T GS+ C TC PGY + CED++EC ++ C G C+N GSF C+
Sbjct: 829 TPGSYSC----TCPPGYVFRTETETCEDINECE--SNPCVNG-ACRNNLGSFNCECSPGS 881
Query: 796 --------CMDG-----FLQDPEGNC-VDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
C+D +L + C V+IN T SE C + + C+R L
Sbjct: 882 KLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECC----ATLGAAWGSPCERCEL 937
Query: 842 --ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC 899
C RG A G C DVNECE C G+ C N GS+ C+C G D GR C
Sbjct: 938 DTACPRGL-ARIKGVTCEDVNECEVFPGVCPNGR-CVNSKGSFHCECPEGLTLDGTGRVC 995
Query: 900 IDVN--ECWASPGR-LCQHTCENTLGSYRCSCASGFLLAADGKRCE-------------- 942
+D+ +C+ C H C CA G AA G CE
Sbjct: 996 LDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG---AAWGTECEECPKPGTKEYETLC 1052
Query: 943 --------------------DVNECEA--QRCSQ-ECANIYGSYQCYCRQGYQLAEDGHT 979
D+NEC+A C+ +C N GS++C C G+ L +
Sbjct: 1053 PRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERN 1112
Query: 980 CTDIDECAQGAGILCTFRCLNVPGSYQCAC---PEQGYTMTANGRSCKDVDECALGTHNC 1036
CTDIDEC + + C+N PGS++C C E G+ M N C D+DEC C
Sbjct: 1113 CTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKN---CMDIDECERNPLLC 1169
Query: 1037 SEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
TC N +GSF+C +CP + + R C D EC S
Sbjct: 1170 -RGGTCVNTEGSFQC---DCPLGH----ELSPSREDCVDINECSLS 1207
Score = 200 bits (508), Expect = 8e-51
Identities = 155/528 (29%), Positives = 209/528 (39%), Gaps = 104/528 (19%)
Query: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC--------CVSYLQEKSCMAGVL 494
E C G D C ++ E + C + C C+ C G+
Sbjct: 2276 ECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI-------CPPGMA 2328
Query: 495 GAKEGETCGAEDNDSC----GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVML 550
+GE C D + C GI +C + G CE N G+ +
Sbjct: 2329 RRPDGEGC--VDENECRTKPGICENGRCVNIIG--------SYRCECNE--GFQSSSSGT 2376
Query: 551 SCCEGEEPLIVPEVRRPPEPAAAPRR--VSEAEMAGREALSLGTEAEL------------ 596
C + + L EV + A+ R V+++E G + EL
Sbjct: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
Query: 597 -PN----SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPP 651
P+ + G D DEC ++P CINT+GS+ C C G++ G +C
Sbjct: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC-----ID 2491
Query: 652 QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIM 711
E Q P PC +C GS CSC GY +
Sbjct: 2492 LDECSQSPK---------------------------PCNYICKNTEGSYQCSCPRGYVLQ 2524
Query: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMG 771
DG +C+D++EC T H C CVNTLG F C C PG+ C D +EC
Sbjct: 2525 EDGKTCKDLDECQTKQHNCQ--FLCVNTLGGFTC----KCPPGFTQHHTACIDNNECGSQ 2578
Query: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINT 830
C +CQNT GSF C+ C GF D G NC D++EC + C+ G C N
Sbjct: 2579 PSLCGAKGICQNTPGSFSCE----CQRGFSLDATGLNCEDVDECDG-NHRCQHG--CQNI 2631
Query: 831 VGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
+G Y C C +GY +CVD NEC + + CG C+N GSY+C C +GF
Sbjct: 2632 LGGYRCG-----CPQGYIQHYQWNQCVDENEC-SNPNACGSAS-CYNTLGSYKCACPSGF 2684
Query: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADG 938
D F C DVNEC +S C + C NT G Y C C G+ G
Sbjct: 2685 SFDQFSSACHDVNEC-SSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG 2731
Score = 199 bits (505), Expect = 2e-50
Identities = 206/731 (28%), Positives = 281/731 (38%), Gaps = 130/731 (17%)
Query: 397 AWIPPTREVPRKPQ-----VLPHSHVEEDTDPNSVHSIPRSSPEGS---TKDLIETCCAA 448
AW P P +PQ +P+ D + +IP G+ T E C A
Sbjct: 246 AWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPA 305
Query: 449 GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKEGETCGAED 506
G + + +C +I E +C T + C + + C+ G + + +G C +
Sbjct: 306 GHKQSETTQKCEDIDECSIIPGICETGE---CSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
Query: 507 NDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR 566
C L C L R C CCE + +
Sbjct: 363 TGMCFSGLVN---GRCAQELPGRMTKMQC----------------CCEPGRCWGIGTI-- 401
Query: 567 PPEPAAAPRRVSEA-EMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVG 625
P A P R SE + L +G S PG G G
Sbjct: 402 ---PEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGN----------G 448
Query: 626 SYHCACFPGFSLQDDGRTCRPE-GHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCK 684
+ + GF G P G Q P + + + TI + N C
Sbjct: 449 NGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITG--LTILNQTIDICKHHANLCL 506
Query: 685 DNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFH 744
NG C S S C C GY A+G C D++EC ++ C+ G+ CVNT GS++
Sbjct: 507 -NGRCIPTVS----SYRCECNMGYKQDANG-DCIDVDECTSN--PCTNGD-CVNTPGSYY 557
Query: 745 CYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
C C G+ + C D+DEC C+ G C NT GSF C C GF
Sbjct: 558 C----KCHAGFQRTPTKQACIDIDECIQNGVLCKNG-RCVNTDGSFQCI----CNAGFEL 608
Query: 803 DPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNE 861
+G NCVD +ECT+ + C G CIN GS+ C IC G+ + +G C DV+E
Sbjct: 609 TTDGKNCVDHDECTT-TNMCLNGM-CINEDGSFKC-----ICKPGFVLAPNGRYCTDVDE 661
Query: 862 CET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE---------------- 904
C+T G+ C G C N GS+RCDC G GR C+D +
Sbjct: 662 CQTPGI--CMNGH-CINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRP 718
Query: 905 ----------CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--E 948
C A+P G CQ + C+SG + DG+ D+NEC +
Sbjct: 719 FPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGR---DINECALD 775
Query: 949 AQRCSQE-CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1007
C+ C N+ GSY+C C GY+ G C DIDEC + C N PGSY C
Sbjct: 776 PDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSC 835
Query: 1008 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTK 1067
CP GY +C+D++EC ++ C C N GSF C EC P SK
Sbjct: 836 TCP-PGYVFRTETETCEDINECE--SNPCVNG-ACRNNLGSFNC---ECSPG----SKLS 884
Query: 1068 CERTTCHDFLE 1078
C D L+
Sbjct: 885 STGLICIDSLK 895
Score = 183 bits (465), Expect = 7e-46
Identities = 189/699 (27%), Positives = 267/699 (38%), Gaps = 140/699 (20%)
Query: 443 ETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVLGAKEGE 500
E C+ G D C +I E ++C Q C + E C+ G + + + +
Sbjct: 1265 ECSCSEGYALMPDGRSCADIDECENNPDICDGGQ---CTNIPGEYRCLCYDGFMASMDMK 1321
Query: 501 TCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI 560
TC D + C ++ + C G +G S + LGY C + +E I
Sbjct: 1322 TC--IDVNECDLN-----SNICMFGECENTKG-SFICHCQLGYSVKKGTTGCTDVDECEI 1373
Query: 561 VPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHL- 619
S + G S E + N + D DEC + +
Sbjct: 1374 GAH--------NCDMHASCLNIPGSFKCSC-REGWIGNGIKCIDLDECSNGTHQCSINAQ 1424
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQ 679
C+NT GSY CAC GF+ DG TC S+ + A N
Sbjct: 1425 CVNTPGSYRCACSEGFT--GDGFTC------------------SDVDECAENI------- 1457
Query: 680 PNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNT 739
N C +NG C V G+ C C G+ +D SC+DI+EC + C G C N
Sbjct: 1458 -NLC-ENGQCLNV----PGAYRCECEMGFTPASDSRSCQDIDECSFQ-NICVFGT-CNNL 1509
Query: 740 LGSFHCYKALTCEPGYALK--DGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCM 797
G FHC C+ GY L G C D+DECA + C G LC NT G + C C
Sbjct: 1510 PGMFHCI----CDDGYELDRTGGNCTDIDECADPIN-CVNG-LCVNTPGRYECN----CP 1559
Query: 798 DGFLQDPEG-NCVD--INECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG-------- 846
F +P G CVD + C P G NT R+ C+ G
Sbjct: 1560 PDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE 1619
Query: 847 ----YHASDDGTKCV---------------DVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
++++ T C D++EC+ C +G C N GS++C+C
Sbjct: 1620 TCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC-QGGNCINTFGSFQCECP 1678
Query: 888 AGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC 947
G+ R C D++EC+A PG TC NTLG+Y C C ++ G C D+ +
Sbjct: 1679 QGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKS 1738
Query: 948 EAQR------CSQE---------CANIY------------------GSYQCYCRQGYQLA 974
R C E C Y ++ C
Sbjct: 1739 FCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFT 1798
Query: 975 EDGHT--CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1032
D HT DIDEC + GI C+N GS++C CP G++ C+D+DEC+ G
Sbjct: 1799 FDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECP-TGFSYNDLLLVCEDIDECSNG 1857
Query: 1033 THNCSEAETCHNIQGSFRC---LRFECPPNYVQVSKTKC 1068
+ C C N GS+RC F+ PN V + +C
Sbjct: 1858 DNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNEC 1896
Score = 96.7 bits (239), Expect = 1e-19
Identities = 94/386 (24%), Positives = 137/386 (35%), Gaps = 73/386 (18%)
Query: 641 GRTCRPEGHPPQPEAPQEPALKSEFSQVASN---TIPLPLPQPNTCKDNGPCKQVCSTVG 697
G +P+ PP+P PQ P + + S P + + +
Sbjct: 25 GTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLR 84
Query: 698 GSAICS------CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKA--L 749
G +C C PG+ + G N+C+ + C N+ G C +
Sbjct: 85 GPNVCGSRFHSYCCPGWKTLPGG------NQCIVPI--------CRNSCGDGFCSRPNMC 130
Query: 750 TCEPGYALKDGECEDVDECA---MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 806
TC G + + +C+ M TC CQ KG Q + Q+ G
Sbjct: 131 TCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH-CQCQKGYIGTYCGQPVCENGCQNG-G 188
Query: 807 NCVDINECTSL-------------SEPC------------RPGFSCINTVGSYT------ 835
C+ N C + + PC G C T+ T
Sbjct: 189 RCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG 248
Query: 836 -----CQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
C P C RG+ + C DV+EC+ C +G C N GS+ C C AG
Sbjct: 249 HPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAGH 307
Query: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCED--VNECE 948
++ + C D++EC PG C NT+GSY C C G++ + DG RC D C
Sbjct: 308 KQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCF 367
Query: 949 A----QRCSQECANIYGSYQCYCRQG 970
+ RC+QE QC C G
Sbjct: 368 SGLVNGRCAQELPGRMTKMQCCCEPG 393
Score = 94.0 bits (232), Expect = 8e-19
Identities = 91/295 (30%), Positives = 116/295 (39%), Gaps = 60/295 (20%)
Query: 768 CAMGTHT-CQPGFLCQNTKGSFYCQA---RQRCMDGFLQDPEGNCVDINECTSLSEPCRP 823
C H+ C PG+ + G C R C DGF P N CT C
Sbjct: 89 CGSRFHSYCCPGW--KTLPGGNQCIVPICRNSCGDGFCSRP-------NMCT-----CSS 134
Query: 824 GFSCINTVGSYTCQRNPLICARGYHASDDGTKC--------VDVNECETGVHRCGEGQVC 875
G +T GS + Q+ + C G +DD +C CE G C G C
Sbjct: 135 G-QISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG---CQNGGRC 190
Query: 876 HNLPGSYRCDCKAGF-----QRDAFGRGCI-DVNE----------------CWASPGRLC 913
G RC C GF +RD C VN C A+ GR
Sbjct: 191 I---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
Query: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQ-ECANIYGSYQCYCRQG 970
H CE + C GF+ C+DV+EC+A C C N GS++C C G
Sbjct: 248 GHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAG 306
Query: 971 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
++ +E C DIDEC+ GI T C N GSY C CP +GY + +G C D
Sbjct: 307 HKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCP-RGYVTSTDGSRCID 360
Score = 59.7 bits (143), Expect = 2e-08
Identities = 67/264 (25%), Positives = 94/264 (35%), Gaps = 59/264 (22%)
Query: 827 CINTVGSYTCQR-NPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD 885
C N+ G C R N C+ G +S G+K + +C RC G C C
Sbjct: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSK--SIQQCSV---RCMNGGTC----ADDHCQ 165
Query: 886 CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCEN---TLGSYRCSCASGFLLAADGKRCE 942
C+ G+ G C P +C++ C+N +G RC+C GF
Sbjct: 166 CQKGY----IGTYC-------GQP--VCENGCQNGGRCIGPNRCACVYGFT--------- 203
Query: 943 DVNECEAQRCSQECANIYGSYQCYCRQGYQLAED---GHTCTDIDECAQGAGILCTFRCL 999
+C Y + C+ + Q+ + G CT CA G C
Sbjct: 204 ----------GPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCAT-IGRAWGHPCE 252
Query: 1000 NVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPN 1059
P Q +G+ +C+DVDEC C + C N GSF C CP
Sbjct: 253 MCPAQPQPC--RRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFEC---RCPAG 306
Query: 1060 YVQVSKTKCERTTCHDFLECQNSP 1083
+ Q T+ C D EC P
Sbjct: 307 HKQSETTQ----KCEDIDECSIIP 326
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 266 bits (679), Expect = 1e-70
Identities = 204/631 (32%), Positives = 262/631 (41%), Gaps = 153/631 (24%)
Query: 506 DNDSCGISL---YKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVP 562
D D CG++L Y+ CC +G G CE+ P+ P + S C
Sbjct: 922 DEDECGVTLPGKYRMDVCCCSIGA---VWGVECEACPD---PESLEFASLC--------- 966
Query: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCI 621
PR + A R+ LS + D +EC + PG LC H C
Sbjct: 967 -----------PRGLG---FASRDFLSGRPFYK--------DVNECKVFPG-LCTHGTCR 1003
Query: 622 NTVGSYHCACFPGFSLQDDGRTCR--------PE--------GHPPQPEAPQEPALKSEF 665
NTVGS+HCAC GF+L R C P+ P E P +S F
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIMADGVSC 717
+ + C D C + C+ GS C C PG+ + A G +C
Sbjct: 1064 MLMKN------------CMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Query: 718 EDINECVTDLHTCSRGE----------------------------------------HCV 737
EDI+EC C G+ HC+
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCI 1171
Query: 738 NTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 795
NT GS+ C +C GY+L DG C DVDEC C G C N G C
Sbjct: 1172 NTEGSYRC----SCGQGYSLMPDGRACADVDECEENPRVCDQGH-CTNMPGGHRCL---- 1222
Query: 796 CMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGT 854
C DGF+ P+ CVD++EC C G C NT GS+ C C GY T
Sbjct: 1223 CYDGFMATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVCH-----CQLGYMVRKGAT 1276
Query: 855 KCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC- 913
C DV+ECE G H C C N+PGS+ C C G+ D F C D++EC + R
Sbjct: 1277 GCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGF--ECHDLDECVSQEHRCSP 1334
Query: 914 QHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQ-ECANIYGSYQCYCRQG 970
+ C N GSYRC+C GF A DG CED +EC C +C N G Y+C C G
Sbjct: 1335 RGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMG 1392
Query: 971 YQLAEDGHTCTDIDECAQGAGILCTF-RCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1029
+ ED C D+DECAQG LC F C N+PG ++C C GY + G +C D++EC
Sbjct: 1393 FDPTEDHRACQDVDECAQGN--LCAFGSCENLPGMFRCIC-NGGYELDRGGGNCTDINEC 1449
Query: 1030 ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
A NC C N GS+ C CP ++
Sbjct: 1450 A-DPVNCING-VCINTPGSYLC---SCPQDF 1475
Score = 242 bits (618), Expect = 1e-63
Identities = 176/544 (32%), Positives = 234/544 (43%), Gaps = 91/544 (16%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGR--------TCRPEGHPPQPEA 655
D DECL P +C N GSY C C PG L G TC + + E
Sbjct: 766 DVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEV 823
Query: 656 P-QEPALKSEFSQVASNTIPLPLPQPN---------------TCKDNGPCKQV------- 692
Q +L+SE P + TC D C+
Sbjct: 824 NLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNG 883
Query: 693 -CSTVGGSAICSCFPGYAIMADGVSCEDI-----------NECVTDLHTCSRGEHCVNTL 740
C GS C C G + A G C D+ +EC L R + C ++
Sbjct: 884 RCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSI 943
Query: 741 GSFHCYKALTCEP--------------GYALKDGEC-----EDVDECAMGTHTCQPGFLC 781
G+ + C G+A +D +DV+EC + C G C
Sbjct: 944 GAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHG-TC 1002
Query: 782 QNTKGSFYCQARQRCMDGFLQDP-EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
+NT GSF+C C GF D E NC DI+EC + C G +C+NT GS+ C+
Sbjct: 1003 RNTVGSFHCA----CAGGFALDAQERNCTDIDECRISPDLCGQG-TCVNTPGSFECE--- 1054
Query: 841 LICARGYHASDDGTK-CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC 899
C GY + K C+DV+EC C G C N GSY+C C G + A G C
Sbjct: 1055 --CFPGYESGFMLMKNCMDVDECARDPLLC-RGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Query: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQEC 956
D++EC S G LC H C N +G+++CSC +GF D + C D+NEC Q C C
Sbjct: 1112 EDIDECSLSDG-LCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHC 1170
Query: 957 ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTM 1016
N GSY+C C QGY L DG C D+DEC + + C N+PG ++C C + G+
Sbjct: 1171 INTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYD-GFMA 1229
Query: 1017 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDF 1076
T + R+C DVDEC L H C + C N +GSF C C Y+ + T C D
Sbjct: 1230 TPDMRTCVDVDECDLNPHICLHGD-CENTKGSFVC---HCQLGYM----VRKGATGCSDV 1281
Query: 1077 LECQ 1080
EC+
Sbjct: 1282 DECE 1285
Score = 241 bits (615), Expect = 3e-63
Identities = 181/558 (32%), Positives = 232/558 (41%), Gaps = 111/558 (19%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTC------------------- 644
D DEC P C N+ GS+ C C PGF L D+G C
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 645 ---------------RP-EGH-PPQPEAPQE-PALKSEFSQVASNTIPLP---LPQPNTC 683
RP EG P PQE A E +P P N C
Sbjct: 2029 PKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNEC 2088
Query: 684 KDN-GPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLG 741
+N G C VC GS C C GY++ G++C D +EC H C +G C N +G
Sbjct: 2089 AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVG-HPCGQGT-CTNVIG 2146
Query: 742 SFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF- 800
F C A EPG + CED+DEC++ C F C NT+GS+ C C G+
Sbjct: 2147 GFECACADGFEPGLMMT---CEDIDECSLNPLLC--AFRCHNTEGSYLCT----CPAGYT 2197
Query: 801 LQDPEGNCVDINECTSLSEPCRP-GFSCINTVGSYTCQRNPLICARGYHA-SDDGTKCVD 858
L++ C D++EC + C G C N +G++ C +C G G C D
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFAC-----VCPPGMRPLPGSGEGCTD 2252
Query: 859 VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVN--------------- 903
NEC C G+ C N GS+RCDC GFQ C D+
Sbjct: 2253 DNECHAQPDLCVNGR-CVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRS 2311
Query: 904 -----------ECWASPGRLCQHTCENT----LGSYRCSCASGFLLAADGKRCEDVNECE 948
EC GR CE +YR C G A+G+ DV+EC
Sbjct: 2312 LSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGR---DVDECR 2368
Query: 949 --AQRCSQ-ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
A C+ EC N GS++C+C+ GY TC D+DEC+Q CTF C N GS+
Sbjct: 2369 MLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQ-VPKPCTFLCKNTKGSF 2427
Query: 1006 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
C+CP +GY + +GR+CKD+DEC HNC C N G+F C CPP + Q
Sbjct: 2428 LCSCP-RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNTVGAFTC---RCPPGFTQ--- 2478
Query: 1066 TKCERTTCHDFLECQNSP 1083
C D EC P
Sbjct: 2479 ---HHQACFDNDECSAQP 2493
Score = 239 bits (611), Expect = 9e-63
Identities = 228/802 (28%), Positives = 308/802 (38%), Gaps = 154/802 (19%)
Query: 432 SSPEGSTKDLIETCCAA--GQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSC 489
S P+ CC+ G+ W D C P+ G+ Q C +
Sbjct: 2027 SVPKAFNTTKTRCCCSKRPGEGWG---DPCELCPQEGSA-----AFQELCPFGH------ 2072
Query: 490 MAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ-SCESNPNLGYPCNHV 548
GA G ED + C + C G+ V +G CE GY +
Sbjct: 2073 -----GAVPGPDDSREDVNECA-----ENPGVCTNGVCVNTDGSFRCECP--FGYSLDFT 2120
Query: 549 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDEC 608
++C + +E V P + E A + G + +D DEC
Sbjct: 2121 GINCVDTDEC----SVGHPCGQGTCTNVIGGFECACADGFEPGL------MMTCEDIDEC 2170
Query: 609 LLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAP---QEPALKSEF 665
L P LC C NT GSY C C G++L++DG CR + + K+
Sbjct: 2171 SLNP-LLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLI 2229
Query: 666 SQVASNTIPLPLPQPNT---CKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADG 714
A P P P + C D+ C C GS C C G+
Sbjct: 2230 GTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTL 2289
Query: 715 VSCEDI--------------------NECVTDLHTCSRG--------EHCVNTLGSFHCY 746
C DI +E VT C G E C L Y
Sbjct: 2290 TECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELC--PLPGTSAY 2347
Query: 747 KALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG 806
+ L C G E DVDEC M H C G C N+ GSF C C G+ D
Sbjct: 2348 RKL-CPHGSGYT-AEGRDVDECRMLAHLCAHGE-CINSLGSFRCH----CQAGYTPDATA 2400
Query: 807 N-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETG 865
C+D++EC+ + +PC F C NT GS+ C C RGY +DG C D++EC +
Sbjct: 2401 TTCLDMDECSQVPKPCT--FLCKNTKGSFLCS-----CPRGYLLEEDGRTCKDLDECTSR 2453
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-CENTLGSY 924
H C +C N G++ C C GF + + C D +EC A PG H C NT GS+
Sbjct: 2454 QHNCQF--LCVNTVGAFTCRCPPGFTQHH--QACFDNDECSAQPGPCGAHGHCHNTPGSF 2509
Query: 925 RCSCASGFLLAADGKRCEDVNECEA-QRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDI 983
RC C GF L + G CEDVNEC+ RC C N G Y+C C QG+ C D
Sbjct: 2510 RCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDE 2569
Query: 984 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCH 1043
+ECA + C N G ++C CP G+ C++VDECA CS + C
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPS-GFDFDQALGGCQEVDECAGRRGPCSYS--CA 2626
Query: 1044 NIQGSFRCLRFECPPNYVQVSKTKC-----------------ERTTCHDFLECQ------ 1080
N G F C CP Y + + C E + EC+
Sbjct: 2627 NTPGGFLC---GCPQGYFRAGQGHCVSGLGFSPGPQDTPDKEELLSSEACYECKINGLSP 2683
Query: 1081 -NSPARITH--YQLNFQTG-----LLVPAHIFRIGPA-------PAFTG--DTIALNIIK 1123
+ P R H +Q+N T L + ++ +G A PA G I I++
Sbjct: 2684 RDRPRRSAHRDHQVNLATLDSEALLTLGLNLSHLGRAERILELRPALEGLEGRIRYVIVR 2743
Query: 1124 GNEEGYFGTRRLNAYTGVVYLQ 1145
GNE+G+F R++ GV LQ
Sbjct: 2744 GNEQGFF---RMHHLRGVSSLQ 2762
Score = 238 bits (608), Expect = 2e-62
Identities = 209/736 (28%), Positives = 275/736 (37%), Gaps = 163/736 (22%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVC------RTAQRHCCVSYLQEKSCMAGVLGAKEG 499
C G + C +I E T +C T + CV C A L G
Sbjct: 1590 CPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCV-------CPAEYLQVNGG 1642
Query: 500 ETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPL 559
C C ++ C L + C + N+G N
Sbjct: 1643 NNCMDMRKSVC----FRHYNGTCQNELAFNVTRKMCCCSYNIGQAWN------------- 1685
Query: 560 IVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHL 619
RP E P + G +A T+ L D DEC +P +
Sbjct: 1686 ------RPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPL---DIDECGEIPAICANGI 1736
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAP---QEPALKSEFSQVASNTIPLP 676
CIN +GS+ C C GF+ C E+P + S T
Sbjct: 1737 CINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYK 1796
Query: 677 LPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLH 728
L C C+++ C GS +C C G+ AD C DI+EC D
Sbjct: 1797 LSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDEC--DRQ 1854
Query: 729 TCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGECEDVDEC-AMGTHTCQPGFLCQNTKG 786
C G C N +GS++C C PG+ + +G+C D DEC + C+ G C NT G
Sbjct: 1855 PCGNGT-CKNIIGSYNC----LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGH-CLNTAG 1908
Query: 787 SFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICAR 845
SF+C C DGF +G NCVD NEC SL+ C PG +C N GS+ C IC
Sbjct: 1909 SFHC----LCQDGFELTADGKNCVDTNECLSLAGTCLPG-TCQNLEGSFRC-----ICPP 1958
Query: 846 GYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDV--- 902
G+ D C+D++EC + C G C N PGS++C C GF G C D
Sbjct: 1959 GFQVQSD--HCIDIDECSEEPNLCLFG-TCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQS 2015
Query: 903 ------------------------------NECWASPGRLC--------QHTCENTLGSY 924
E W P LC Q C G+
Sbjct: 2016 FCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAV 2075
Query: 925 -----------RCS-----CASGFLLAADGK-RCE---------------DVNECE-AQR 951
C+ C +G + DG RCE D +EC
Sbjct: 2076 PGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP 2135
Query: 952 CSQ-ECANIYGSYQCYCRQGYQLAEDG--HTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1008
C Q C N+ G ++C C G+ E G TC DIDEC+ +LC FRC N GSY C
Sbjct: 2136 CGQGTCTNVIGGFECACADGF---EPGLMMTCEDIDECSLNP-LLCAFRCHNTEGSYLCT 2191
Query: 1009 CPEQGYTMTANGRSCKDVDECALGTHNC-SEAETCHNIQGSFRCLRFECPPNYVQVSKTK 1067
CP GYT+ +G C+DVDECA G +C + C N+ G+F C+ CPP +
Sbjct: 2192 CP-AGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACV---CPPG---MRPLP 2244
Query: 1068 CERTTCHDFLECQNSP 1083
C D EC P
Sbjct: 2245 GSGEGCTDDNECHAQP 2260
Score = 231 bits (589), Expect = 3e-60
Identities = 186/563 (33%), Positives = 235/563 (41%), Gaps = 120/563 (21%)
Query: 603 DDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDG-----RTCRP------EGHP 650
+D DEC Q+ CIN GSY C C G+ L G CR G
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDC 1821
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYA 709
E F A T+ + + + C D PC C + GS C CFPG+
Sbjct: 1822 MDTEGSYMCLCHRGFQASADQTLCMDIDE---C-DRQPCGNGTCKNIIGSYNCLCFPGFV 1877
Query: 710 IMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDE 767
+ +G C D +EC T + R HC+NT GSFHC C+ G+ L DG+ C D +E
Sbjct: 1878 VTHNG-DCVDFDECTTLVGQVCRFGHCLNTAGSFHCL----CQDGFELTADGKNCVDTNE 1932
Query: 768 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINEC----------TSL 817
C TC PG CQN +GSF C C GF Q +C+DI+EC T
Sbjct: 1933 CLSLAGTCLPG-TCQNLEGSFRCI----CPPGF-QVQSDHCIDIDECSEEPNLCLFGTCT 1986
Query: 818 SEP------CRPGF-------SCINTVGSYT-----------------------CQRNP- 840
+ P C PGF C +T S+ C + P
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPG 2046
Query: 841 -------------------LICARGYHA---SDDGTKCVDVNECETGVHRCGEGQVCHNL 878
+C G+ A DD + DVNEC C G VC N
Sbjct: 2047 EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSRE--DVNECAENPGVCTNG-VCVNT 2103
Query: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC-QHTCENTLGSYRCSCASGFLLAAD 937
GS+RC+C G+ D G C+D +EC S G C Q TC N +G + C+CA GF
Sbjct: 2104 DGSFRCECPFGYSLDFTGINCVDTDEC--SVGHPCGQGTCTNVIGGFECACADGFEPGLM 2161
Query: 938 GKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCT 995
CED++EC C+ C N GSY C C GY L EDG C D+DECA G C
Sbjct: 2162 -MTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQD-CH 2219
Query: 996 FR---CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
R C N+ G++ C CP + +G C D +EC C C N GSFRC
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGR-CVNTAGSFRC- 2277
Query: 1053 RFECPPNYVQVSKTKCERTTCHD 1075
+C + Q S T T CHD
Sbjct: 2278 --DCDEGF-QPSPT---LTECHD 2294
Score = 222 bits (566), Expect = 1e-57
Identities = 214/736 (29%), Positives = 289/736 (39%), Gaps = 127/736 (17%)
Query: 437 STKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMA--GVL 494
+T+ + C AG + + D C++ E T +C C++ SC+ G L
Sbjct: 507 NTEGSFQCVCNAGFELSPDGKNCVDHNECATS-TMCVNG---VCLNEDGSFSCLCKPGFL 562
Query: 495 GAKEGETCGAEDNDSC---GISLYKQC--------CDCCGLGLRVRAEGQSCESNPNLGY 543
A G C D D C GI + C C C G GL V +G+ C
Sbjct: 563 LAPGGHYC--MDIDECQTPGICVNGHCTNTEGSFRCQCLG-GLAVGTDGRVCVDTHVRST 619
Query: 544 PCNHVMLSCCEGEEPLIVPEVR----RPPEPAAAPRRVSEA-EMAGREALSLGTEAELPN 598
+ C P V + P P ++ A + A +AL + L
Sbjct: 620 CYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALC---SSGLGI 676
Query: 599 SLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE 658
+ G D +EC L P +C N GSY C C G+ G+ C E
Sbjct: 677 TTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD---------VDE 727
Query: 659 PALKS-----EFSQVASNTIPLPLP-------QPNTCKD-----NGPC-KQVCSTVGGSA 700
AL S + Q + + P CKD + PC VC + GS
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSY 787
Query: 701 ICSCFPGYAIMADGVSCEDI-----------NECVTDLHTCSRGEHCVNTLGSF------ 743
C C PG + G C D + C +L S C TLG+
Sbjct: 788 TCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCE 847
Query: 744 HCYKALTCEPGYALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
C C G+A G C+DV+EC C P C NT GSF C+ C +G +
Sbjct: 848 RCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCVNTAGSFRCE----CPEGLML 902
Query: 803 DPEGN-CVDI-----------NEC-TSLSEPCRPGFSC--INTVGSYTCQRNP------- 840
D G CVD+ +EC +L R C I V C+ P
Sbjct: 903 DASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEF 962
Query: 841 -LICARGY-HASDDGTK----CVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 894
+C RG AS D DVNEC+ C G C N GS+ C C GF DA
Sbjct: 963 ASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHG-TCRNTVGSFHCACAGGFALDA 1021
Query: 895 FGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC----ASGFLLAADGKRCEDVNECEAQ 950
R C D++EC SP Q TC NT GS+ C C SGF+L K C DV+EC
Sbjct: 1022 QERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLM---KNCMDVDECARD 1078
Query: 951 RC---SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQC 1007
C N GSY+C C G++L G C DIDEC+ G+ +C+NV G++QC
Sbjct: 1079 PLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQC 1138
Query: 1008 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTK 1067
+C G+ T + + C D++EC + C C N +GS+RC C Y +
Sbjct: 1139 SC-HAGFQSTPDRQGCVDINECRVQNGGCD--VHCINTEGSYRC---SCGQGYSLMP--- 1189
Query: 1068 CERTTCHDFLECQNSP 1083
+ C D EC+ +P
Sbjct: 1190 -DGRACADVDECEENP 1204
Score = 214 bits (545), Expect = 4e-55
Identities = 179/573 (31%), Positives = 229/573 (39%), Gaps = 120/573 (20%)
Query: 596 LPNSLPG--DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRP------ 646
+PN G D DEC +PG LCQ C+N VGS+HC C G L D C
Sbjct: 237 IPNIHTGACQDVDECQAVPG-LCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGAC 295
Query: 647 -------------EGH----------------PPQPEAPQEPALKSEFSQVASNTIPLPL 677
GH P PE P +EF Q+ + +PL
Sbjct: 296 FSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPEL-CPPRGSNEFQQLCAQRLPLLP 354
Query: 678 PQPNTC------------KDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVT 725
P GP + I S PG + + + I+ C
Sbjct: 355 GHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRH 414
Query: 726 DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGECEDVDECAMGTHTCQPGFLCQNT 784
+ C G C+ T S+ C C GY GEC DVDEC + C G C N
Sbjct: 415 FTNLCLNG-RCLPTPSSYRC----ECNVGYTQDVRGECIDVDECT--SSPCHHGD-CVNI 466
Query: 785 KGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLIC 843
G+++C RC GF P CVD++EC C G C+NT GS+ C +C
Sbjct: 467 PGTYHC----RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-----VC 516
Query: 844 ARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVN 903
G+ S DG CVD NEC T C G VC N GS+ C CK GF G C+D++
Sbjct: 517 NAGFELSPDGKNCVDHNECATST-MCVNG-VCLNEDGSFSCLCKPGFLLAPGGHYCMDID 574
Query: 904 ECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN-------ECEAQRCSQ-- 954
EC +PG C NT GS+RC C G + DG+ C D + E C++
Sbjct: 575 EC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPF 633
Query: 955 -------EC-----------------ANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA 990
EC A +Q C G + DG DI+ECA
Sbjct: 634 PGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR---DINECALDP 690
Query: 991 GILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFR 1050
+ C N+ GSY+C C GY A+G+ C DVDECAL + C C N GS+
Sbjct: 691 EVCANGVCENLRGSYRCVC-NLGYEAGASGKDCTDVDECALNSLLCDNG-WCQNSPGSYS 748
Query: 1051 CLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
C CPP + T+ C D EC +SP
Sbjct: 749 C---SCPPGFHFWQDTE----ICKDVDECLSSP 774
Score = 206 bits (523), Expect = 1e-52
Identities = 205/747 (27%), Positives = 273/747 (36%), Gaps = 173/747 (23%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQ--EKSCMAGVLGAKEGETCG 503
C G + C +I E D +C Q CV+ + + SC AG + + C
Sbjct: 1098 CPPGHELTAKGTACEDIDECSLSDGLCPHGQ---CVNVIGAFQCSCHAGFQSTPDRQGC- 1153
Query: 504 AEDNDSCGISLYKQCCDC------------CGLGLRVRAEGQSCESNPNLGYPCNHVMLS 551
D + C + CD CG G + +G++C +
Sbjct: 1154 -VDINECRVQ--NGGCDVHCINTEGSYRCSCGQGYSLMPDGRACAD------------VD 1198
Query: 552 CCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLL 611
CE E P + + P G L P+ D DEC L
Sbjct: 1199 ECE-ENPRVCDQGHCTNMPG------------GHRCLCYDGFMATPDMRTCVDVDECDLN 1245
Query: 612 PGELCQHL-CINTVGSYHCACFPGFSLQ------DDGRTCRPEGHPPQPEAPQEPALKSE 664
P +C H C NT GS+ C C G+ ++ D C GH
Sbjct: 1246 P-HICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGH--------------- 1289
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECV 724
N C + GS C C PG+ + DG C D++ECV
Sbjct: 1290 ---------------------NCDSHASCLNIPGSFSCRCLPGW--VGDGFECHDLDECV 1326
Query: 725 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNT 784
+ H CS C+N GS+ C TC G+A CED DECA C G C N
Sbjct: 1327 SQEHRCSPRGDCLNVPGSYRC----TCRQGFAGDGFFCEDRDECAENVDLCDNG-QCLNA 1381
Query: 785 KGSFYCQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
G + C+ C GF DP + C D++EC C G SC N G + C
Sbjct: 1382 PGGYRCE----CEMGF--DPTEDHRACQDVDECAQ-GNLCAFG-SCENLPGMFRC----- 1428
Query: 842 ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
IC GY G C D+NEC V+ C G VC N PGSY C C F+ + G GC+D
Sbjct: 1429 ICNGGYELDRGGGNCTDINECADPVN-CING-VCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 902 VN-----------------------------ECWASPGRLCQHTCE-----NTLGSYRCS 927
C S GR + CE NT YR
Sbjct: 1487 TRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTT-EYRTL 1545
Query: 928 C--ASGFLLAADGKRCEDVNECE--AQRC-SQECANIYGSYQCYCRQGYQLAEDGHTCTD 982
C GF ED++EC+ C +C N +GS+QC C GY L+E C D
Sbjct: 1546 CPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICED 1605
Query: 983 IDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE--CALGTHNCSEAE 1040
IDEC+ +GI C N G+Y C CP + Y G +C D+ + C + + E
Sbjct: 1606 IDECSTHSGICGPGTCYNTLGNYTCVCPAE-YLQVNGGNNCMDMRKSVCFRHYNGTCQNE 1664
Query: 1041 TCHNIQGSFRCLRFECPPNYVQVSKTKCER-----TTCHDFLECQNSPARITHYQLNFQT 1095
N+ C C N Q CE + + L +P +T + T
Sbjct: 1665 LAFNVTRKMCC----CSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLT----DIHT 1716
Query: 1096 GLLVPAHIFRIGPAPAFTGDTIALNII 1122
G P I G PA + I +N I
Sbjct: 1717 G--KPLDIDECGEIPAICANGICINQI 1741
Score = 199 bits (506), Expect = 1e-50
Identities = 138/403 (34%), Positives = 186/403 (46%), Gaps = 70/403 (17%)
Query: 693 CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCE 752
C S C C GY G C D++EC + C G+ CVN G++HC C
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRG-ECIDVDECTSS--PCHHGD-CVNIPGTYHC----RCY 475
Query: 753 PGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCV 809
PG+ C DVDEC + C G C NT+GSF C C GF P+G NCV
Sbjct: 476 PGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQCV----CNAGFELSPDGKNCV 530
Query: 810 DINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET-GVHR 868
D NEC + S C G C+N GS++C +C G+ + G C+D++EC+T G+
Sbjct: 531 DHNECAT-STMCVNGV-CLNEDGSFSC-----LCKPGFLLAPGGHYCMDIDECQTPGI-- 581
Query: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE------------------------ 904
C G C N GS+RC C G GR C+D +
Sbjct: 582 CVNGH-CTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 905 --CWASP----GRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQRCSQE- 955
C A+P G CQ ++ C+SG + DG+ D+NEC + + C+
Sbjct: 641 ECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR---DINECALDPEVCANGV 697
Query: 956 CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYT 1015
C N+ GSY+C C GY+ G CTD+DECA + + C N PGSY C+CP G+
Sbjct: 698 CENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCP-PGFH 756
Query: 1016 MTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1058
+ CKDVDEC + C C N+ GS+ C +C P
Sbjct: 757 FWQDTEICKDVDECL--SSPCVSG-VCRNLAGSYTC---KCGP 793
Score = 188 bits (478), Expect = 2e-47
Identities = 164/565 (29%), Positives = 230/565 (40%), Gaps = 103/565 (18%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPA- 660
+D+DEC +LC + C+N G Y C C GF +D R C+ Q +
Sbjct: 1361 EDRDECAENV-DLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSC 1419
Query: 661 --LKSEFSQVASNTIPLP-----LPQPNTCKDNGPC-KQVCSTVGGSAICSCFPGYAIMA 712
L F + + L N C D C VC GS +CSC + +
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNP 1479
Query: 713 DGVSCEDINECVTDLHTCSRGE----------------HCVNTLGSFH------CYKALT 750
GV C D L T RG+ C +LG C A T
Sbjct: 1480 SGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANT 1539
Query: 751 CEPGYALKDGE----------CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
E GE ED+DEC CQ G C NT GSF C+ C G+
Sbjct: 1540 TEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGD-CVNTFGSFQCE----CPPGY 1594
Query: 801 -LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDV 859
L + C DI+EC++ S C PG +C NT+G+YTC +C Y + G C+D+
Sbjct: 1595 HLSEHTRICEDIDECSTHSGICGPG-TCYNTLGNYTC-----VCPAEYLQVNGGNNCMDM 1648
Query: 860 NECETGVHRCGEGQ----------VC---HNLPGSYRCDCKA------------------ 888
+ H G Q +C +N+ ++ C+A
Sbjct: 1649 RKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAP 1708
Query: 889 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
GF D +D++EC P C N +GS+RC C +GF + CEDV+EC
Sbjct: 1709 GFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECG 1768
Query: 949 AQR--CSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1004
++ C Q +C NI GSY+C C +GY+L+ G C +EC + + C++ GS
Sbjct: 1769 SRESPCQQNADCINIPGSYRCKCTRGYKLSPGG-ACVGRNECREIPNVCSHGDCMDTEGS 1827
Query: 1005 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1064
Y C C +G+ +A+ C D+DEC C TC NI GS+ CL C P +V
Sbjct: 1828 YMCLC-HRGFQASADQTLCMDIDEC--DRQPCGNG-TCKNIIGSYNCL---CFPGFVVT- 1879
Query: 1065 KTKCERTTCHDFLECQNSPARITHY 1089
C DF EC ++ +
Sbjct: 1880 ----HNGDCVDFDECTTLVGQVCRF 1900
Score = 182 bits (463), Expect = 1e-45
Identities = 150/475 (31%), Positives = 192/475 (40%), Gaps = 103/475 (21%)
Query: 604 DQDECLLLPGELCQHL--CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
D DEC++ G LC HL C+NT GS+ C C GF L DG+ C
Sbjct: 489 DVDECIV-SGGLC-HLGRCVNTEGSFQCVCNAGFELSPDGKNC----------------- 529
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
+ ++ A++T+ + NG VC GS C C PG+ + G C DI+
Sbjct: 530 -VDHNECATSTMCV----------NG----VCLNEDGSFSCLCKPGFLLAPGGHYCMDID 574
Query: 722 ECVTDLHTCSRGEHCVNTLGSFHC------------------YKALTCEPGYALKDGECE 763
EC T C G HC NT GSF C + TC A++ G C
Sbjct: 575 ECQTP-GICVNG-HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYG--AIEKGSCA 630
Query: 764 -------DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTS 816
EC G CQ + + C G +G DINEC
Sbjct: 631 RPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGR--DINECAL 688
Query: 817 LSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH 876
E C G C N GSY C +C GY A G C DV+EC C G C
Sbjct: 689 DPEVCANGV-CENLRGSYRC-----VCNLGYEAGASGKDCTDVDECALNSLLCDNGW-CQ 741
Query: 877 NLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAA 936
N PGSY C C GF C DV+EC +SP C N GSY C C G L
Sbjct: 742 NSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTCKCGPGSRLDP 799
Query: 937 DGKRCEDVN------ECEAQRC----------SQECANIYGSY-----QC----YCRQGY 971
G C D + + RC S+ CA + ++ +C C +G+
Sbjct: 800 SGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGF 859
Query: 972 QLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDV 1026
G TC D++EC G+ RC+N GS++C CPE G + A+GR C DV
Sbjct: 860 -ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPE-GLMLDASGRLCVDV 912
Score = 182 bits (461), Expect = 2e-45
Identities = 159/533 (29%), Positives = 209/533 (39%), Gaps = 128/533 (24%)
Query: 614 ELCQH---LCIN-----TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF 665
++C+H LC+N T SY C C G++ QD ++ E
Sbjct: 410 DICRHFTNLCLNGRCLPTPSSYRCECNVGYT-QD---------------------VRGEC 447
Query: 666 SQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSCEDINECV 724
V T + PC C + G+ C C+PG+ +C D++EC+
Sbjct: 448 IDVDECT-------------SSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECI 494
Query: 725 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECAMGTHTCQPGFLCQ 782
C G CVNT GSF C C G+ L DG+ C D +ECA T C G +C
Sbjct: 495 VSGGLCHLG-RCVNTEGSFQC----VCNAGFELSPDGKNCVDHNECATST-MCVNG-VCL 547
Query: 783 NTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGF----SCINTVGSYTCQ 837
N GSF C C GFL P G+ C+DI+EC + PG C NT GS+ CQ
Sbjct: 548 NEDGSFSC----LCKPGFLLAPGGHYCMDIDECQT------PGICVNGHCTNTEGSFRCQ 597
Query: 838 RNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSY-RCDCKAGFQRDAFG 896
C G DG CVD + T +G PG+ + +C FG
Sbjct: 598 -----CLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFG 652
Query: 897 RGC-------------------------IDVNECWASPGRLCQHTCENTLGSYRCSCASG 931
C D+NEC P CEN GSYRC C G
Sbjct: 653 EPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLG 712
Query: 932 FLLAADGKRCEDVNECEAQRCSQE---CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQ 988
+ A GK C DV+EC + C N GSY C C G+ +D C D+DEC
Sbjct: 713 YEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLS 772
Query: 989 GAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE--CALGTHNCSEAETCHNIQ 1046
+ + C N+ GSY C C G + +G C D + C L E+ N+Q
Sbjct: 773 SPCV--SGVCRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWL---KIQESRCEVNLQ 826
Query: 1047 GSFRCLRFECPPNYVQVSKTKCER----------------TTCHDFLECQNSP 1083
G+ LR EC + CER TC D EC++ P
Sbjct: 827 GA--SLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFP 877
Score = 151 bits (382), Expect = 3e-36
Identities = 136/455 (29%), Positives = 181/455 (39%), Gaps = 74/455 (16%)
Query: 675 LPLPQPNTCKDNGPCKQV--------CSTVGGSAICSCFPGYAIMADGVSCEDINE--CV 724
+P C+D C+ V C + GS C C G+ + +CED C
Sbjct: 237 IPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Query: 725 TDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDV----------DECAM---- 770
+ L G C L + + C+ G G ++ CA
Sbjct: 297 SVLF----GGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPL 352
Query: 771 --GTHTCQPGFLCQNTKGSFYCQARQRCMD------GFLQDPEGNC--------VDINEC 814
G PG L + G R G GN I+ C
Sbjct: 353 LPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDIC 412
Query: 815 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 874
+ C G C+ T SY C+ C GY D +C+DV+EC + G+
Sbjct: 413 RHFTNLCLNG-RCLPTPSSYRCE-----CNVGY-TQDVRGECIDVDECTSSPCHHGD--- 462
Query: 875 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL 934
C N+PG+Y C C GFQ + C+DV+EC S G C NT GS++C C +GF L
Sbjct: 463 CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFEL 522
Query: 935 AADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGI 992
+ DGK C D NEC + C N GS+ C C+ G+ LA GH C DIDEC Q GI
Sbjct: 523 SPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDEC-QTPGI 581
Query: 993 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
C N GS++C C G + +GR C D TH S TC+ C
Sbjct: 582 CVNGHCTNTEGSFRCQC-LGGLAVGTDGRVCVD-------THVRS---TCYGAIEKGSCA 630
Query: 1053 RFECPPNYVQVSKTK-CERTTCHDFLE-CQNSPAR 1085
R P V+K++ C H F E CQ PA+
Sbjct: 631 R----PFPGTVTKSECCCANPDHGFGEPCQLCPAK 661
Score = 151 bits (381), Expect = 4e-36
Identities = 125/401 (31%), Positives = 170/401 (42%), Gaps = 57/401 (14%)
Query: 693 CSTVGGS-----AICSCFP-----GYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGS 742
C+TVG + +C P G+ +C+D++EC C G CVN +GS
Sbjct: 211 CATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGS 269
Query: 743 FHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY-----CQARQRCM 797
FHC C G+ L D D A + G C Y C R RC
Sbjct: 270 FHC----RCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCW 325
Query: 798 DG----FLQDPEGNCVDINECTSLSEPCRPG----FSCINTVGSY-------TCQRNPL- 841
L P G+ + + + P PG F + GS + NP
Sbjct: 326 AAGPVPELCPPRGS-NEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHG 384
Query: 842 -----ICARGYHASDDGTKCVD--VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDA 894
I + G S+ GT ++ ++ C + C G+ C P SYRC+C G+ +D
Sbjct: 385 SDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGR-CLPTPSSYRCECNVGYTQDV 443
Query: 895 FGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC--EAQR 951
G CIDV+EC +SP C H C N G+Y C C GF + C DV+EC
Sbjct: 444 RGE-CIDVDECTSSP---CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGL 499
Query: 952 CS-QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP 1010
C C N GS+QC C G++L+ DG C D +ECA + CLN GS+ C C
Sbjct: 500 CHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATST-MCVNGVCLNEDGSFSCLC- 557
Query: 1011 EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
+ G+ + G C D+DEC T C N +GSFRC
Sbjct: 558 KPGFLLAPGGHYCMDIDECQ--TPGICVNGHCTNTEGSFRC 596
Score = 59.3 bits (142), Expect = 2e-08
Identities = 79/291 (27%), Positives = 106/291 (36%), Gaps = 84/291 (28%)
Query: 738 NTLGS-FHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ-- 794
N GS FH Y C PG+ G +C + +C+ G +C
Sbjct: 58 NVCGSRFHAY----CCPGWRTFPGR----SQCVVP--------ICRRACGEGFCSQPNLC 101
Query: 795 RCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL-------ICARGY 847
C DG L G ++ + S C G +C S CQ+ IC RG
Sbjct: 102 TCADGTLAPSCG----VSRGSGCSVSCMNGGTCRGA--SCLCQKGYTGTVCGQPICDRGC 155
Query: 848 HASDDGTKCVDVNECETGV----------HRCGE--GQV----C-HNLPG---------- 880
H +G +C+ N C +R G GQV C H L G
Sbjct: 156 H---NGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCA 212
Query: 881 ------SYRCD--------CKAGFQRDAFGRGCIDVNECWASPGRLCQ-HTCENTLGSYR 925
C+ C+ GF + C DV+EC A PG LCQ +C N +GS+
Sbjct: 213 TVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPG-LCQGGSCVNMVGSFH 271
Query: 926 CSCASGFLLAADGKRCED--VNECEA----QRCSQECANIYGSYQCYCRQG 970
C C G L+ CED C + RC+ + A Y QC C +G
Sbjct: 272 CRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Score = 59.3 bits (142), Expect = 2e-08
Identities = 65/244 (26%), Positives = 91/244 (37%), Gaps = 52/244 (21%)
Query: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRP------GFSC-INTVGSYTCQRNPLICAR 845
R+ C +GF P N CT P G C ++ + TC+ +C +
Sbjct: 87 RRACGEGFCSQP-------NLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQK 139
Query: 846 GYHASDDGTKCVDVNECETGVHRCGEGQVCHN---LPGSYRCDCKAGFQRDAFGRGCIDV 902
GY GT C G C G CHN G RC C GF R
Sbjct: 140 GY----TGTVC--------GQPICDRG--CHNGGRCIGPNRCACVYGFMGPQCERD-YRT 184
Query: 903 NECWASPG-RLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYG 961
C+ G CQH + + CA+ + A G CE C AQ
Sbjct: 185 GPCFGQVGPEGCQHQLTGLVCTKALCCAT--VGRAWGLPCE---LCPAQPHP-------- 231
Query: 962 SYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGR 1021
CR+G+ C D+DEC G+ C+N+ GS+ C CP G+ ++ +
Sbjct: 232 -----CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCP-VGHRLSDSSA 285
Query: 1022 SCKD 1025
+C+D
Sbjct: 286 ACED 289
Score = 47.4 bits (111), Expect = 8e-05
Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 36/237 (15%)
Query: 865 GVHRCGEGQVCHNLPG----SYRCDCKAGFQRDAFGRG-CIDVNECWASPGRL------- 912
G + CG + PG R C R A G G C N C + G L
Sbjct: 56 GPNVCGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVS 115
Query: 913 ----CQHTCEN--TLGSYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQ 964
C +C N T C C G+ G+ D RC CA +YG
Sbjct: 116 RGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMG 175
Query: 965 CYCRQGYQLAEDGHTCTDIDECAQGAGILCT--FRCLNVPGSYQCACP---------EQG 1013
C + Y+ Q G++CT C V ++ C +G
Sbjct: 176 PQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRG 235
Query: 1014 YTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKCE 1069
+ + +C+DVDEC C + +C N+ GSF C CP + + S CE
Sbjct: 236 FIPNIHTGACQDVDECQAVPGLC-QGGSCVNMVGSFHC---RCPVGHRLSDSSAACE 288
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 265 bits (678), Expect = 1e-70
Identities = 222/700 (31%), Positives = 293/700 (41%), Gaps = 98/700 (14%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 424 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 470
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 471 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 514
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 515 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 559
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 560 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 617
Query: 618 HLCINTVGSYHCAC---FPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVA---SN 671
C N GS+ C C F G + ++D C E P P A + A S
Sbjct: 618 GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
Query: 672 TIPLPLPQPNTC-KDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHT 729
P + C + PC C GS C C G+ G CED++EC + H
Sbjct: 678 GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHL 735
Query: 730 CSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
G+ CVN+ GSF C TC G+ L G C DVDEC+ G C P C NT+GSF
Sbjct: 736 ACPGQECVNSPGSFQCR---TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 792
Query: 790 CQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 846
C C G+ + P G C D+NEC + C P C+NT GS+ C CA G
Sbjct: 793 CS----CAPGY-RAPSGRPGPCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPG 841
Query: 847 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECW 906
Y G C+DV+EC C G +C N GS+ C C G + C+DV+EC
Sbjct: 842 YRPGPRGASCLDVDECSEE-DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
Query: 907 ASPGRLC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANI 959
LC CEN+ GSYRC C G+ +G C+DV+EC+ + C +Q C N
Sbjct: 900 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENT 958
Query: 960 YGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
GSY+C C GYQ G C D+DEC + C N+PGS+QC C +QGY
Sbjct: 959 PGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGA 1016
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1057
+GR C DV+EC C A C N++GSF C+ CP
Sbjct: 1017 RDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CP 1052
Score = 254 bits (649), Expect = 3e-67
Identities = 208/626 (33%), Positives = 268/626 (42%), Gaps = 98/626 (15%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 358 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 414
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 415 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 471
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 472 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 529
Query: 656 PQEPALKSEFSQVASNTIPLP----LPQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 530 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 588
Query: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC- 762
C GY G SC+D++EC C RG C N GSF C C G+ + C
Sbjct: 589 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC----VCPAGF--RGSACE 641
Query: 763 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPC 821
EDVDECA C PG C NT GSF+C C GF + P C D++EC PC
Sbjct: 642 EDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPC 696
Query: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGS 881
G C NT GS+ C +C G+ + G++C DV+ECE H GQ C N PGS
Sbjct: 697 TYG-RCENTEGSFQC-----VCPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 748
Query: 882 YRC-DCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGK 939
++C C +G GR C DV+EC + H C NT GS+RCSCA G+ A G+
Sbjct: 749 FQCRTCPSGHHLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGR 805
Query: 940 --RCEDVNEC-EAQRC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
C DVNEC E C EC N GS+ C C GY+ G +C D+DEC++ +
Sbjct: 806 PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQ 864
Query: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1054
+ C N GS++C CP G+ + SC DVDEC ++ C N GS+RC+R
Sbjct: 865 SGICTNTDGSFECICP-PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR- 922
Query: 1055 ECPPNYVQVSKTKCERTTCHDFLECQ 1080
+C P Y TC D ECQ
Sbjct: 923 DCDPGY-----HAGPEGTCDDVDECQ 943
Score = 250 bits (638), Expect = 6e-66
Identities = 173/509 (33%), Positives = 228/509 (44%), Gaps = 55/509 (10%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR--PEGH--PPQPEAPQEP 659
D DEC +P C N+ GS+ C C PGF C E H PP + +
Sbjct: 520 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 579
Query: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIM 711
F V P +C+D C Q C + GS C C G+
Sbjct: 580 NTPGSFLCVCPAGYQ-AAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR-- 636
Query: 712 ADGVSC-EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK--DGECEDVDEC 768
G +C ED++EC + C G C NT GSFHC C G+ + C+DVDEC
Sbjct: 637 --GSACEEDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDEC 689
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSC 827
A C G C+NT+GSF C C GF + G+ C D++EC + PG C
Sbjct: 690 ARSPPPCTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECE--NHLACPGQEC 742
Query: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
+N+ GS+ C+ C G+H +C DV+EC +G CG C N GS+RC C
Sbjct: 743 VNSPGSFQCR----TCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 796
Query: 888 AGFQRDAFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 946
G++ + G C DVNEC C NT GS+ C+CA G+ G C DV+E
Sbjct: 797 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE 856
Query: 947 CEAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPG 1003
C + Q C N GS++C C G++ D +C D+DEC + LC + RC N PG
Sbjct: 857 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 916
Query: 1004 SYQCA--CPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061
SY+C C + GY G +C DVDEC A+ C N GS+RC C P Y
Sbjct: 917 SYRCVRDC-DPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQ 973
Query: 1062 QVSKTKCE-------RTTCHDFLECQNSP 1083
C+ R+ C CQN P
Sbjct: 974 PTPGGGCQDVDECRNRSFCGAHAVCQNLP 1002
Score = 164 bits (416), Expect = 4e-40
Identities = 221/874 (25%), Positives = 295/874 (33%), Gaps = 173/874 (19%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 485
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 486 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 544
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 605 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 662
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 663 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 719 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 778
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDF--------- 820
Query: 675 LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGE 734
C +G C GS C+C PGY G SC D++EC ++ C G
Sbjct: 821 --------CFPHGECLNT----DGSFACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGI 867
Query: 735 HCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 792
C NT GSF C C PG+ C DVDEC C+N+ GS+ C
Sbjct: 868 -CTNTDGSFECI----CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV- 921
Query: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
+ C G+ PEG C D++EC C NT GSY C C GY +
Sbjct: 922 -RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP---ACDPGYQPTPG 977
Query: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
G C DV+EC CG VC NLPGS++C C G++ GR C+DVNEC
Sbjct: 978 GG-CQDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC------- 1028
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVN----ECEAQRCS---------QECANI 959
T + G+ C G L E+ + C R S Q A+
Sbjct: 1029 --ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1086
Query: 960 Y------------------------GSYQCYCRQGYQLAEDGHTCTDIDE----CAQGAG 991
G +CY A D ++ C G G
Sbjct: 1087 VLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEG 1146
Query: 992 ILCTFRCLNVPGS----YQCACPE-QGYTMTANGRSCK-DVDECALGTHNCSEAETCHNI 1045
R PG+ YQ CP +GY + S + DVDEC L ++ C N
Sbjct: 1147 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNT 1206
Query: 1046 QGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
+ C C Y +R C D EC
Sbjct: 1207 APGYSCY---CSNGYYY----HTQRLECIDNDEC 1233
Score = 144 bits (364), Expect = 4e-34
Identities = 189/717 (26%), Positives = 252/717 (35%), Gaps = 136/717 (18%)
Query: 406 PRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDL---IETCCAAGQQWAI---DNDEC 459
P Q PH +D D + P G+ K+L C AG + + D DEC
Sbjct: 590 PAGYQAAPHGASCQDVDECT--QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 647
Query: 460 LEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGIS----LY 515
+ P TA C +C AG G C +D D C S Y
Sbjct: 648 AQEPPPCGPGRCDNTAGSFHC-------ACPAGFRSRGPGAPC--QDVDECARSPPPCTY 698
Query: 516 KQCCDC-------CGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVP------ 562
+C + C +G + G CE NH+ C G+E + P
Sbjct: 699 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECE---NHL---ACPGQECVNSPGSFQCR 752
Query: 563 -----------------EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
E P + E + R + + G A P D
Sbjct: 753 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
Query: 606 DECLLLPGELC--QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
+ECL G+ C C+NT GS+ C C PG+ G +C + + Q +
Sbjct: 813 NECL--EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTN 870
Query: 664 EFSQVASNTIPLPLPQPNT--------CKDNGPC---KQVCSTVGGSAIC--SCFPGYAI 710
P P+ C++ GP Q C GS C C PGY
Sbjct: 871 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 930
Query: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECA 769
+G +C+D++EC + C NT GS+ C A C+PGY G C+DVDEC
Sbjct: 931 GPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECR 987
Query: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCI 828
+ C +CQN GSF C C G+ +G +CVD+NEC +L C C
Sbjct: 988 NRSF-CGAHAVCQNLPGSFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CE 1041
Query: 829 NTVGSYTCQRNPLICARGYHASDDGT-KCVDVNECETGVHRCGEGQVCHN---------- 877
N GS+ C +C D T +CV G + Q +
Sbjct: 1042 NVEGSFLC-----VCPNSPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPP 1095
Query: 878 -LP-----------GSYRCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQ 914
LP GS R +C + + C V E W S R+ Q
Sbjct: 1096 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1155
Query: 915 HTCENT-LGSYRCSCASGF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCY 966
C T Y+ C G LA G DV+EC+ R C S C N Y CY
Sbjct: 1156 --CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1213
Query: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C GY C D DECA RC+N GSY C C E + + R C
Sbjct: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1269
Score = 83.2 bits (204), Expect = 1e-15
Identities = 142/577 (24%), Positives = 196/577 (33%), Gaps = 143/577 (24%)
Query: 420 DTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQR-- 477
D D S + +S +T E C G + D CL++ E +QR
Sbjct: 853 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 912
Query: 478 HCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCES 537
+ SY + C G EG TC +D D C + + CG Q CE+
Sbjct: 913 NSPGSYRCVRDCDPGYHAGPEG-TC--DDVDEC----QEYGPEICG--------AQRCEN 957
Query: 538 NPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
P Y C +C G +P P + V E R G A
Sbjct: 958 TPG-SYRCTP---ACDPGYQPT----------PGGGCQDVDEC----RNRSFCGAHAVCQ 999
Query: 598 NSLPGD-------------------DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ 638
N LPG D +EC L G LC N GS+ C C P +
Sbjct: 1000 N-LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-PNSPEE 1057
Query: 639 DDGRT--CRPE----GHPP--QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
D T C P G P QP+AP P L + P PLP+ + GP
Sbjct: 1058 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPAR-------PPPPPLPRRPSTPRQGP-- 1108
Query: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT 750
VG EC D + + C N L ++
Sbjct: 1109 -----VGSGR--------------------RECYFDT---AAPDACDNILARNVTWQECC 1140
Query: 751 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV- 809
C G G C + +C GT T + LC + +G P G+
Sbjct: 1141 CTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA--------------PSGDLSL 1183
Query: 810 --DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 866
D++EC + C+ G C+NT Y+C C+ GY+ +C+D +EC
Sbjct: 1184 RRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADEE 1237
Query: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DVNECWASPGR--LCQH 915
C EG C N GSY C C+ D R C+ ++ CW G +C H
Sbjct: 1238 PAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSH 1296
Query: 916 TCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 949
+ +Y C C G D C +D ++ EA
Sbjct: 1297 PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1333
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 938 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 988
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
Query: 989 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
A LC RCLN GS++C C G+ T C
Sbjct: 1516 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1550
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 20/179 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPL-----PQPNTCKDNGPCKQVCSTVGGSAICSCF 705
P EA E ++E + A P + P+ + D + G S
Sbjct: 176 PWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPL 235
Query: 706 PGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECE 763
PG + V C +H C + C LG+ A C G+ +G CE
Sbjct: 236 PG--LRTQEVCCRGAG-LAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCE 289
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 821
DVDECA G CQ G C NT+G + C C DGFL D +C+ + + PC
Sbjct: 290 DVDECATGGR-CQHG-ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 342
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 923
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1532
Query: 924 YRCSCASGF 932
+RC C GF
Sbjct: 1533 FRCICRPGF 1541
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 865 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 917
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 253 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 305
Query: 918 ENTLGSYRCSCASGFLLAADGKRC 941
NT G Y C C GFLL + C
Sbjct: 306 ANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 47.8 bits (112), Expect = 6e-05
Identities = 74/321 (23%), Positives = 116/321 (36%), Gaps = 64/321 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 85 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 140
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
Query: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDEC 768
++A ED S +C L C L PG ++ C
Sbjct: 201 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPL---PGLRTQEVCCRGAG-L 250
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQR--CMDGFLQDPEGNCVDINECTSLSEPCRPGFS 826
A G H CQ LC G+ + C GF + G+C D++EC + C+ G
Sbjct: 251 AWGVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECATGGR-CQHG-E 304
Query: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVD---VNECETGVHRCGEGQVC-----HNL 878
C NT G YTC +C G+ + C+ ++E + R C N+
Sbjct: 305 CANTRGGYTC-----VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 359
Query: 879 PGSYRCDCKAGFQRDAFGRGC 899
C + G A+GRGC
Sbjct: 360 TKQICCCSRVG---KAWGRGC 377
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1452 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1502
Query: 1021 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1503 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 954
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1465 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
Query: 955 --ECANIYGSYQCYCRQGYQLAEDGHTC 980
C N GS++C CR G+ H C
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 45.1 bits (105), Expect = 4e-04
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYA 709
P+PE P E S S P + C C C V C CF GY
Sbjct: 1443 PEPEEPPEGG-----SYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYR 1497
Query: 710 IMADGVSCEDINEC--VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA 756
+ ++C DINEC C+NT GSF C C PG+A
Sbjct: 1498 LDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC----ICRPGFA 1542
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 746 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 803
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1500
Query: 804 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1550
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 809 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 865
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1465 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGF 890
C + C N GS+RC C+ GF
Sbjct: 1518 SPLCVNAR-CLNTDGSFRCICRPGF 1541
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 913 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 965
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 314
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1017
C G+ L +C ++ G C+ L C C G
Sbjct: 315 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 371
Query: 1018 ANGRSCK 1024
A GR C+
Sbjct: 372 AWGRGCQ 378
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 986 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1034
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 244 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 298
Query: 1035 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1068
C E C N +G + C+ CP + + S++ C
Sbjct: 299 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 329
Score = 35.8 bits (81), Expect = 0.25
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 289 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 32.3 bits (72), Expect = 2.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1526 CLNTDGSFRCICRPGFAPTHQPHHCAP 1552
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 265 bits (678), Expect = 1e-70
Identities = 222/700 (31%), Positives = 293/700 (41%), Gaps = 98/700 (14%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 454 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 500
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 501 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 544
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 545 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 589
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 590 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 647
Query: 618 HLCINTVGSYHCAC---FPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVA---SN 671
C N GS+ C C F G + ++D C E P P A + A S
Sbjct: 648 GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 707
Query: 672 TIPLPLPQPNTC-KDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHT 729
P + C + PC C GS C C G+ G CED++EC + H
Sbjct: 708 GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHL 765
Query: 730 CSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
G+ CVN+ GSF C TC G+ L G C DVDEC+ G C P C NT+GSF
Sbjct: 766 ACPGQECVNSPGSFQCR---TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 822
Query: 790 CQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 846
C C G+ + P G C D+NEC + C P C+NT GS+ C CA G
Sbjct: 823 CS----CAPGY-RAPSGRPGPCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPG 871
Query: 847 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECW 906
Y G C+DV+EC C G +C N GS+ C C G + C+DV+EC
Sbjct: 872 YRPGPRGASCLDVDECSEE-DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECR 929
Query: 907 ASPGRLC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANI 959
LC CEN+ GSYRC C G+ +G C+DV+EC+ + C +Q C N
Sbjct: 930 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENT 988
Query: 960 YGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
GSY+C C GYQ G C D+DEC + C N+PGS+QC C +QGY
Sbjct: 989 PGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGA 1046
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1057
+GR C DV+EC C A C N++GSF C+ CP
Sbjct: 1047 RDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CP 1082
Score = 254 bits (649), Expect = 3e-67
Identities = 208/626 (33%), Positives = 268/626 (42%), Gaps = 98/626 (15%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 388 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 444
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 445 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 501
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 502 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 559
Query: 656 PQEPALKSEFSQVASNTIPLP----LPQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 560 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 618
Query: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC- 762
C GY G SC+D++EC C RG C N GSF C C G+ + C
Sbjct: 619 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC----VCPAGF--RGSACE 671
Query: 763 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPC 821
EDVDECA C PG C NT GSF+C C GF + P C D++EC PC
Sbjct: 672 EDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPC 726
Query: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGS 881
G C NT GS+ C +C G+ + G++C DV+ECE H GQ C N PGS
Sbjct: 727 TYG-RCENTEGSFQC-----VCPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 778
Query: 882 YRC-DCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGK 939
++C C +G GR C DV+EC + H C NT GS+RCSCA G+ A G+
Sbjct: 779 FQCRTCPSGHHLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGR 835
Query: 940 --RCEDVNEC-EAQRC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
C DVNEC E C EC N GS+ C C GY+ G +C D+DEC++ +
Sbjct: 836 PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQ 894
Query: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1054
+ C N GS++C CP G+ + SC DVDEC ++ C N GS+RC+R
Sbjct: 895 SGICTNTDGSFECICP-PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR- 952
Query: 1055 ECPPNYVQVSKTKCERTTCHDFLECQ 1080
+C P Y TC D ECQ
Sbjct: 953 DCDPGY-----HAGPEGTCDDVDECQ 973
Score = 250 bits (638), Expect = 6e-66
Identities = 173/509 (33%), Positives = 228/509 (44%), Gaps = 55/509 (10%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR--PEGH--PPQPEAPQEP 659
D DEC +P C N+ GS+ C C PGF C E H PP + +
Sbjct: 550 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 609
Query: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIM 711
F V P +C+D C Q C + GS C C G+
Sbjct: 610 NTPGSFLCVCPAGYQ-AAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR-- 666
Query: 712 ADGVSC-EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK--DGECEDVDEC 768
G +C ED++EC + C G C NT GSFHC C G+ + C+DVDEC
Sbjct: 667 --GSACEEDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDEC 719
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSC 827
A C G C+NT+GSF C C GF + G+ C D++EC + PG C
Sbjct: 720 ARSPPPCTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECE--NHLACPGQEC 772
Query: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
+N+ GS+ C+ C G+H +C DV+EC +G CG C N GS+RC C
Sbjct: 773 VNSPGSFQCR----TCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 826
Query: 888 AGFQRDAFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 946
G++ + G C DVNEC C NT GS+ C+CA G+ G C DV+E
Sbjct: 827 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE 886
Query: 947 CEAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPG 1003
C + Q C N GS++C C G++ D +C D+DEC + LC + RC N PG
Sbjct: 887 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 946
Query: 1004 SYQCA--CPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061
SY+C C + GY G +C DVDEC A+ C N GS+RC C P Y
Sbjct: 947 SYRCVRDC-DPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQ 1003
Query: 1062 QVSKTKCE-------RTTCHDFLECQNSP 1083
C+ R+ C CQN P
Sbjct: 1004 PTPGGGCQDVDECRNRSFCGAHAVCQNLP 1032
Score = 164 bits (416), Expect = 4e-40
Identities = 221/874 (25%), Positives = 295/874 (33%), Gaps = 173/874 (19%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 460 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 515
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 516 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 574
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 575 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 635 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 692
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 693 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 748
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 749 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 808
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDF--------- 850
Query: 675 LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGE 734
C +G C GS C+C PGY G SC D++EC ++ C G
Sbjct: 851 --------CFPHGECLNT----DGSFACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGI 897
Query: 735 HCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 792
C NT GSF C C PG+ C DVDEC C+N+ GS+ C
Sbjct: 898 -CTNTDGSFECI----CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV- 951
Query: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
+ C G+ PEG C D++EC C NT GSY C C GY +
Sbjct: 952 -RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP---ACDPGYQPTPG 1007
Query: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
G C DV+EC CG VC NLPGS++C C G++ GR C+DVNEC
Sbjct: 1008 GG-CQDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC------- 1058
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVN----ECEAQRCS---------QECANI 959
T + G+ C G L E+ + C R S Q A+
Sbjct: 1059 --ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1116
Query: 960 Y------------------------GSYQCYCRQGYQLAEDGHTCTDIDE----CAQGAG 991
G +CY A D ++ C G G
Sbjct: 1117 VLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEG 1176
Query: 992 ILCTFRCLNVPGS----YQCACPE-QGYTMTANGRSCK-DVDECALGTHNCSEAETCHNI 1045
R PG+ YQ CP +GY + S + DVDEC L ++ C N
Sbjct: 1177 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNT 1236
Query: 1046 QGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
+ C C Y +R C D EC
Sbjct: 1237 APGYSCY---CSNGYYY----HTQRLECIDNDEC 1263
Score = 144 bits (364), Expect = 4e-34
Identities = 189/717 (26%), Positives = 252/717 (35%), Gaps = 136/717 (18%)
Query: 406 PRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDL---IETCCAAGQQWAI---DNDEC 459
P Q PH +D D + P G+ K+L C AG + + D DEC
Sbjct: 620 PAGYQAAPHGASCQDVDECT--QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 677
Query: 460 LEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGIS----LY 515
+ P TA C +C AG G C +D D C S Y
Sbjct: 678 AQEPPPCGPGRCDNTAGSFHC-------ACPAGFRSRGPGAPC--QDVDECARSPPPCTY 728
Query: 516 KQCCDC-------CGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVP------ 562
+C + C +G + G CE NH+ C G+E + P
Sbjct: 729 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECE---NHL---ACPGQECVNSPGSFQCR 782
Query: 563 -----------------EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
E P + E + R + + G A P D
Sbjct: 783 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 842
Query: 606 DECLLLPGELC--QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
+ECL G+ C C+NT GS+ C C PG+ G +C + + Q +
Sbjct: 843 NECL--EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTN 900
Query: 664 EFSQVASNTIPLPLPQPNT--------CKDNGPC---KQVCSTVGGSAIC--SCFPGYAI 710
P P+ C++ GP Q C GS C C PGY
Sbjct: 901 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 960
Query: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECA 769
+G +C+D++EC + C NT GS+ C A C+PGY G C+DVDEC
Sbjct: 961 GPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECR 1017
Query: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCI 828
+ C +CQN GSF C C G+ +G +CVD+NEC +L C C
Sbjct: 1018 NRSF-CGAHAVCQNLPGSFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CE 1071
Query: 829 NTVGSYTCQRNPLICARGYHASDDGT-KCVDVNECETGVHRCGEGQVCHN---------- 877
N GS+ C +C D T +CV G + Q +
Sbjct: 1072 NVEGSFLC-----VCPNSPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPP 1125
Query: 878 -LP-----------GSYRCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQ 914
LP GS R +C + + C V E W S R+ Q
Sbjct: 1126 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1185
Query: 915 HTCENT-LGSYRCSCASGF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCY 966
C T Y+ C G LA G DV+EC+ R C S C N Y CY
Sbjct: 1186 --CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1243
Query: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C GY C D DECA RC+N GSY C C E + + R C
Sbjct: 1244 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1299
Score = 83.2 bits (204), Expect = 1e-15
Identities = 142/577 (24%), Positives = 196/577 (33%), Gaps = 143/577 (24%)
Query: 420 DTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQR-- 477
D D S + +S +T E C G + D CL++ E +QR
Sbjct: 883 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 942
Query: 478 HCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCES 537
+ SY + C G EG TC +D D C + + CG Q CE+
Sbjct: 943 NSPGSYRCVRDCDPGYHAGPEG-TC--DDVDEC----QEYGPEICG--------AQRCEN 987
Query: 538 NPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
P Y C +C G +P P + V E R G A
Sbjct: 988 TPG-SYRCTP---ACDPGYQPT----------PGGGCQDVDEC----RNRSFCGAHAVCQ 1029
Query: 598 NSLPGD-------------------DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ 638
N LPG D +EC L G LC N GS+ C C P +
Sbjct: 1030 N-LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-PNSPEE 1087
Query: 639 DDGRT--CRPE----GHPP--QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
D T C P G P QP+AP P L + P PLP+ + GP
Sbjct: 1088 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPAR-------PPPPPLPRRPSTPRQGP-- 1138
Query: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT 750
VG EC D + + C N L ++
Sbjct: 1139 -----VGSGR--------------------RECYFDT---AAPDACDNILARNVTWQECC 1170
Query: 751 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV- 809
C G G C + +C GT T + LC + +G P G+
Sbjct: 1171 CTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA--------------PSGDLSL 1213
Query: 810 --DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 866
D++EC + C+ G C+NT Y+C C+ GY+ +C+D +EC
Sbjct: 1214 RRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADEE 1267
Query: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DVNECWASPGR--LCQH 915
C EG C N GSY C C+ D R C+ ++ CW G +C H
Sbjct: 1268 PAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSH 1326
Query: 916 TCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 949
+ +Y C C G D C +D ++ EA
Sbjct: 1327 PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1363
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 938 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 988
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1486 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1545
Query: 989 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
A LC RCLN GS++C C G+ T C
Sbjct: 1546 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1580
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 20/179 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPL-----PQPNTCKDNGPCKQVCSTVGGSAICSCF 705
P EA E ++E + A P + P+ + D + G S
Sbjct: 206 PWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPL 265
Query: 706 PGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECE 763
PG + V C +H C + C LG+ A C G+ +G CE
Sbjct: 266 PG--LRTQEVCCRGAG-LAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCE 319
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 821
DVDECA G CQ G C NT+G + C C DGFL D +C+ + + PC
Sbjct: 320 DVDECATGGR-CQHG-ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 372
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 923
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1506 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1562
Query: 924 YRCSCASGF 932
+RC C GF
Sbjct: 1563 FRCICRPGF 1571
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 865 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 917
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 283 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 335
Query: 918 ENTLGSYRCSCASGFLLAADGKRC 941
NT G Y C C GFLL + C
Sbjct: 336 ANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 47.8 bits (112), Expect = 6e-05
Identities = 74/321 (23%), Positives = 116/321 (36%), Gaps = 64/321 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 115 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 170
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 171 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 230
Query: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDEC 768
++A ED S +C L C L PG ++ C
Sbjct: 231 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPL---PGLRTQEVCCRGAG-L 280
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQR--CMDGFLQDPEGNCVDINECTSLSEPCRPGFS 826
A G H CQ LC G+ + C GF + G+C D++EC + C+ G
Sbjct: 281 AWGVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECATGGR-CQHG-E 334
Query: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVD---VNECETGVHRCGEGQVC-----HNL 878
C NT G YTC +C G+ + C+ ++E + R C N+
Sbjct: 335 CANTRGGYTC-----VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 389
Query: 879 PGSYRCDCKAGFQRDAFGRGC 899
C + G A+GRGC
Sbjct: 390 TKQICCCSRVG---KAWGRGC 407
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1482 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1532
Query: 1021 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1533 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1571
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 954
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1495 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1552
Query: 955 --ECANIYGSYQCYCRQGYQLAEDGHTC 980
C N GS++C CR G+ H C
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 45.1 bits (105), Expect = 4e-04
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYA 709
P+PE P E S S P + C C C V C CF GY
Sbjct: 1473 PEPEEPPEGG-----SYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYR 1527
Query: 710 IMADGVSCEDINEC--VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA 756
+ ++C DINEC C+NT GSF C C PG+A
Sbjct: 1528 LDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC----ICRPGFA 1572
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 746 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 803
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1484 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1530
Query: 804 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1531 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1580
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 809 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 865
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1495 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1547
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGF 890
C + C N GS+RC C+ GF
Sbjct: 1548 SPLCVNAR-CLNTDGSFRCICRPGF 1571
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 913 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 965
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 287 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 344
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1017
C G+ L +C ++ G C+ L C C G
Sbjct: 345 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 401
Query: 1018 ANGRSCK 1024
A GR C+
Sbjct: 402 AWGRGCQ 408
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 986 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1034
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 274 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 328
Query: 1035 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1068
C E C N +G + C+ CP + + S++ C
Sbjct: 329 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 359
Score = 35.8 bits (81), Expect = 0.25
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 319 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 32.3 bits (72), Expect = 2.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1556 CLNTDGSFRCICRPGFAPTHQPHHCAP 1582
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 265 bits (678), Expect = 1e-70
Identities = 222/700 (31%), Positives = 293/700 (41%), Gaps = 98/700 (14%)
Query: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 491 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 537
Query: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
EIPESG +C+ + C C+S +C +G + +
Sbjct: 538 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 581
Query: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
G C D D C ++ C G CE++P + C + E
Sbjct: 582 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 626
Query: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 627 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 684
Query: 618 HLCINTVGSYHCAC---FPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVA---SN 671
C N GS+ C C F G + ++D C E P P A + A S
Sbjct: 685 GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 744
Query: 672 TIPLPLPQPNTC-KDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHT 729
P + C + PC C GS C C G+ G CED++EC + H
Sbjct: 745 GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHL 802
Query: 730 CSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
G+ CVN+ GSF C TC G+ L G C DVDEC+ G C P C NT+GSF
Sbjct: 803 ACPGQECVNSPGSFQCR---TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 859
Query: 790 CQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 846
C C G+ + P G C D+NEC + C P C+NT GS+ C CA G
Sbjct: 860 CS----CAPGY-RAPSGRPGPCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPG 908
Query: 847 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECW 906
Y G C+DV+EC C G +C N GS+ C C G + C+DV+EC
Sbjct: 909 YRPGPRGASCLDVDECSEE-DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECR 966
Query: 907 ASPGRLC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANI 959
LC CEN+ GSYRC C G+ +G C+DV+EC+ + C +Q C N
Sbjct: 967 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENT 1025
Query: 960 YGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
GSY+C C GYQ G C D+DEC + C N+PGS+QC C +QGY
Sbjct: 1026 PGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGA 1083
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1057
+GR C DV+EC C A C N++GSF C+ CP
Sbjct: 1084 RDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CP 1119
Score = 254 bits (649), Expect = 3e-67
Identities = 208/626 (33%), Positives = 268/626 (42%), Gaps = 98/626 (15%)
Query: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 425 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 481
Query: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
EP V P RP PEP PR E + ++ T E
Sbjct: 482 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 538
Query: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 539 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 596
Query: 656 PQEPALKSEFSQVASNTIPLP----LPQPNTCKDNGPCKQV--------CSTVGGSAICS 703
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 597 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 655
Query: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC- 762
C GY G SC+D++EC C RG C N GSF C C G+ + C
Sbjct: 656 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC----VCPAGF--RGSACE 708
Query: 763 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPC 821
EDVDECA C PG C NT GSF+C C GF + P C D++EC PC
Sbjct: 709 EDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPC 763
Query: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGS 881
G C NT GS+ C +C G+ + G++C DV+ECE H GQ C N PGS
Sbjct: 764 TYG-RCENTEGSFQC-----VCPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 815
Query: 882 YRC-DCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGK 939
++C C +G GR C DV+EC + H C NT GS+RCSCA G+ A G+
Sbjct: 816 FQCRTCPSGHHLHR-GR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGR 872
Query: 940 --RCEDVNEC-EAQRC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
C DVNEC E C EC N GS+ C C GY+ G +C D+DEC++ +
Sbjct: 873 PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQ 931
Query: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1054
+ C N GS++C CP G+ + SC DVDEC ++ C N GS+RC+R
Sbjct: 932 SGICTNTDGSFECICP-PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR- 989
Query: 1055 ECPPNYVQVSKTKCERTTCHDFLECQ 1080
+C P Y TC D ECQ
Sbjct: 990 DCDPGY-----HAGPEGTCDDVDECQ 1010
Score = 250 bits (638), Expect = 6e-66
Identities = 173/509 (33%), Positives = 228/509 (44%), Gaps = 55/509 (10%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCR--PEGH--PPQPEAPQEP 659
D DEC +P C N+ GS+ C C PGF C E H PP + +
Sbjct: 587 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCE 646
Query: 660 ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ--------VCSTVGGSAICSCFPGYAIM 711
F V P +C+D C Q C + GS C C G+
Sbjct: 647 NTPGSFLCVCPAGYQ-AAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR-- 703
Query: 712 ADGVSC-EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK--DGECEDVDEC 768
G +C ED++EC + C G C NT GSFHC C G+ + C+DVDEC
Sbjct: 704 --GSACEEDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDEC 756
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSC 827
A C G C+NT+GSF C C GF + G+ C D++EC + PG C
Sbjct: 757 ARSPPPCTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECE--NHLACPGQEC 809
Query: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCK 887
+N+ GS+ C+ C G+H +C DV+EC +G CG C N GS+RC C
Sbjct: 810 VNSPGSFQCR----TCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 863
Query: 888 AGFQRDAFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNE 946
G++ + G C DVNEC C NT GS+ C+CA G+ G C DV+E
Sbjct: 864 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE 923
Query: 947 CEAQRCSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPG 1003
C + Q C N GS++C C G++ D +C D+DEC + LC + RC N PG
Sbjct: 924 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 983
Query: 1004 SYQCA--CPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYV 1061
SY+C C + GY G +C DVDEC A+ C N GS+RC C P Y
Sbjct: 984 SYRCVRDC-DPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQ 1040
Query: 1062 QVSKTKCE-------RTTCHDFLECQNSP 1083
C+ R+ C CQN P
Sbjct: 1041 PTPGGGCQDVDECRNRSFCGAHAVCQNLP 1069
Score = 164 bits (416), Expect = 4e-40
Identities = 221/874 (25%), Positives = 295/874 (33%), Gaps = 173/874 (19%)
Query: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 497 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 552
Query: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
P PG + + SP + + +PP P + + P S
Sbjct: 553 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 611
Query: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
E D + H +P G +T C AG Q A C +
Sbjct: 612 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671
Query: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 672 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 729
Query: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
S + C C G R R G C+ PC + EG + P +P
Sbjct: 730 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 785
Query: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
+ V E E G+E ++ + G D DEC
Sbjct: 786 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 845
Query: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDF--------- 887
Query: 675 LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGE 734
C +G C GS C+C PGY G SC D++EC ++ C G
Sbjct: 888 --------CFPHGECLNT----DGSFACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGI 934
Query: 735 HCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 792
C NT GSF C C PG+ C DVDEC C+N+ GS+ C
Sbjct: 935 -CTNTDGSFECI----CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV- 988
Query: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
+ C G+ PEG C D++EC C NT GSY C C GY +
Sbjct: 989 -RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP---ACDPGYQPTPG 1044
Query: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
G C DV+EC CG VC NLPGS++C C G++ GR C+DVNEC
Sbjct: 1045 GG-CQDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC------- 1095
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVN----ECEAQRCS---------QECANI 959
T + G+ C G L E+ + C R S Q A+
Sbjct: 1096 --ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1153
Query: 960 Y------------------------GSYQCYCRQGYQLAEDGHTCTDIDE----CAQGAG 991
G +CY A D ++ C G G
Sbjct: 1154 VLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEG 1213
Query: 992 ILCTFRCLNVPGS----YQCACPE-QGYTMTANGRSCK-DVDECALGTHNCSEAETCHNI 1045
R PG+ YQ CP +GY + S + DVDEC L ++ C N
Sbjct: 1214 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNT 1273
Query: 1046 QGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
+ C C Y +R C D EC
Sbjct: 1274 APGYSCY---CSNGYYY----HTQRLECIDNDEC 1300
Score = 144 bits (364), Expect = 4e-34
Identities = 189/717 (26%), Positives = 252/717 (35%), Gaps = 136/717 (18%)
Query: 406 PRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDL---IETCCAAGQQWAI---DNDEC 459
P Q PH +D D + P G+ K+L C AG + + D DEC
Sbjct: 657 PAGYQAAPHGASCQDVDECT--QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 714
Query: 460 LEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGIS----LY 515
+ P TA C +C AG G C +D D C S Y
Sbjct: 715 AQEPPPCGPGRCDNTAGSFHC-------ACPAGFRSRGPGAPC--QDVDECARSPPPCTY 765
Query: 516 KQCCDC-------CGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVP------ 562
+C + C +G + G CE NH+ C G+E + P
Sbjct: 766 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECE---NHL---ACPGQECVNSPGSFQCR 819
Query: 563 -----------------EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQ 605
E P + E + R + + G A P D
Sbjct: 820 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 879
Query: 606 DECLLLPGELC--QHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
+ECL G+ C C+NT GS+ C C PG+ G +C + + Q +
Sbjct: 880 NECL--EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTN 937
Query: 664 EFSQVASNTIPLPLPQPNT--------CKDNGPC---KQVCSTVGGSAIC--SCFPGYAI 710
P P+ C++ GP Q C GS C C PGY
Sbjct: 938 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 997
Query: 711 MADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECA 769
+G +C+D++EC + C NT GS+ C A C+PGY G C+DVDEC
Sbjct: 998 GPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECR 1054
Query: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCI 828
+ C +CQN GSF C C G+ +G +CVD+NEC +L C C
Sbjct: 1055 NRSF-CGAHAVCQNLPGSFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CE 1108
Query: 829 NTVGSYTCQRNPLICARGYHASDDGT-KCVDVNECETGVHRCGEGQVCHN---------- 877
N GS+ C +C D T +CV G + Q +
Sbjct: 1109 NVEGSFLC-----VCPNSPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPP 1162
Query: 878 -LP-----------GSYRCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQ 914
LP GS R +C + + C V E W S R+ Q
Sbjct: 1163 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1222
Query: 915 HTCENT-LGSYRCSCASGF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCY 966
C T Y+ C G LA G DV+EC+ R C S C N Y CY
Sbjct: 1223 --CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY 1280
Query: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C GY C D DECA RC+N GSY C C E + + R C
Sbjct: 1281 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1336
Score = 83.2 bits (204), Expect = 1e-15
Identities = 142/577 (24%), Positives = 196/577 (33%), Gaps = 143/577 (24%)
Query: 420 DTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQR-- 477
D D S + +S +T E C G + D CL++ E +QR
Sbjct: 920 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 979
Query: 478 HCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCES 537
+ SY + C G EG TC +D D C + + CG Q CE+
Sbjct: 980 NSPGSYRCVRDCDPGYHAGPEG-TC--DDVDEC----QEYGPEICG--------AQRCEN 1024
Query: 538 NPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
P Y C +C G +P P + V E R G A
Sbjct: 1025 TPG-SYRCTP---ACDPGYQPT----------PGGGCQDVDEC----RNRSFCGAHAVCQ 1066
Query: 598 NSLPGD-------------------DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ 638
N LPG D +EC L G LC N GS+ C C P +
Sbjct: 1067 N-LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-PNSPEE 1124
Query: 639 DDGRT--CRPE----GHPP--QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
D T C P G P QP+AP P L + P PLP+ + GP
Sbjct: 1125 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPAR-------PPPPPLPRRPSTPRQGP-- 1175
Query: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT 750
VG EC D + + C N L ++
Sbjct: 1176 -----VGSGR--------------------RECYFDT---AAPDACDNILARNVTWQECC 1207
Query: 751 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV- 809
C G G C + +C GT T + LC + +G P G+
Sbjct: 1208 CTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA--------------PSGDLSL 1250
Query: 810 --DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 866
D++EC + C+ G C+NT Y+C C+ GY+ +C+D +EC
Sbjct: 1251 RRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADEE 1304
Query: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DVNECWASPGR--LCQH 915
C EG C N GSY C C+ D R C+ ++ CW G +C H
Sbjct: 1305 PAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSH 1363
Query: 916 TCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 949
+ +Y C C G D C +D ++ EA
Sbjct: 1364 PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1400
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 938 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 988
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 1523 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1582
Query: 989 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
A LC RCLN GS++C C G+ T C
Sbjct: 1583 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1617
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 20/179 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPL-----PQPNTCKDNGPCKQVCSTVGGSAICSCF 705
P EA E ++E + A P + P+ + D + G S
Sbjct: 243 PWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPL 302
Query: 706 PGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECE 763
PG + V C +H C + C LG+ A C G+ +G CE
Sbjct: 303 PG--LRTQEVCCRGAG-LAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCE 356
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 821
DVDECA G CQ G C NT+G + C C DGFL D +C+ + + PC
Sbjct: 357 DVDECATGGR-CQHG-ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 409
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 923
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1599
Query: 924 YRCSCASGF 932
+RC C GF
Sbjct: 1600 FRCICRPGF 1608
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 865 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 917
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 320 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 372
Query: 918 ENTLGSYRCSCASGFLLAADGKRC 941
NT G Y C C GFLL + C
Sbjct: 373 ANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 47.8 bits (112), Expect = 6e-05
Identities = 74/321 (23%), Positives = 116/321 (36%), Gaps = 64/321 (19%)
Query: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 152 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 207
Query: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 208 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 267
Query: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDEC 768
++A ED S +C L C L PG ++ C
Sbjct: 268 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPL---PGLRTQEVCCRGAG-L 317
Query: 769 AMGTHTCQPGFLCQNTKGSFYCQARQR--CMDGFLQDPEGNCVDINECTSLSEPCRPGFS 826
A G H CQ LC G+ + C GF + G+C D++EC + C+ G
Sbjct: 318 AWGVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECATGGR-CQHG-E 371
Query: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVD---VNECETGVHRCGEGQVC-----HNL 878
C NT G YTC +C G+ + C+ ++E + R C N+
Sbjct: 372 CANTRGGYTC-----VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 426
Query: 879 PGSYRCDCKAGFQRDAFGRGC 899
C + G A+GRGC
Sbjct: 427 TKQICCCSRVG---KAWGRGC 444
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1519 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1569
Query: 1021 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1570 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1608
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 954
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 1532 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1589
Query: 955 --ECANIYGSYQCYCRQGYQLAEDGHTC 980
C N GS++C CR G+ H C
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 45.1 bits (105), Expect = 4e-04
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYA 709
P+PE P E S S P + C C C V C CF GY
Sbjct: 1510 PEPEEPPEGG-----SYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYR 1564
Query: 710 IMADGVSCEDINEC--VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA 756
+ ++C DINEC C+NT GSF C C PG+A
Sbjct: 1565 LDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC----ICRPGFA 1609
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 746 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 803
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 1521 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1567
Query: 804 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 1568 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1617
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 809 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 865
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 1532 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1584
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGF 890
C + C N GS+RC C+ GF
Sbjct: 1585 SPLCVNAR-CLNTDGSFRCICRPGF 1608
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 913 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 965
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 324 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 381
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1017
C G+ L +C ++ G C+ L C C G
Sbjct: 382 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 438
Query: 1018 ANGRSCK 1024
A GR C+
Sbjct: 439 AWGRGCQ 445
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 21/95 (22%)
Query: 986 CAQGAGI--------LCTFRCLNVPGSYQCACPEQGYTMTANGR---SCKDVDECALGTH 1034
C +GAG+ LC+ R N S + + P+ G T R SC+DVDECA G
Sbjct: 311 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPD-GPCPTGFERVNGSCEDVDECATG-G 365
Query: 1035 NCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1068
C E C N +G + C+ CP + + S++ C
Sbjct: 366 RCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 396
Score = 35.8 bits (81), Expect = 0.25
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 356 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 32.3 bits (72), Expect = 2.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
C+NT GS+ C C PGF+ C P
Sbjct: 1593 CLNTDGSFRCICRPGFAPTHQPHHCAP 1619
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 262 bits (669), Expect = 2e-69
Identities = 144/422 (34%), Positives = 207/422 (49%), Gaps = 55/422 (13%)
Query: 780 LCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQ- 837
LC + G+ A+ +C +GF L G C+DI+EC ++ E CR C+N G Y C
Sbjct: 15 LCLPSPGN----AQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIP 70
Query: 838 -------------------------------------RNPLICARGYHASDDGTKCVDVN 860
PLIC GY D+ +CVDV+
Sbjct: 71 RTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQM-DESNQCVDVD 129
Query: 861 ECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENT 920
EC T H+C Q+C N G Y C C G+ C+D++EC CQ C N
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDIDECRYG---YCQQLCANV 184
Query: 921 LGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQECANIYGSYQCYCRQGYQLAEDGHT 979
GSY C+C GF L DG+ C+DVNEC + C Q C N YGS+ C C GY+L EDG
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVH 244
Query: 980 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEA 1039
C+D+DEC+ LC C+N PG+Y C+CP GY + + RSC+D++EC H C+
Sbjct: 245 CSDMDECSFSE-FLCQHECVNQPGTYFCSCPP-GYILLDDNRSCQDINECEHRNHTCNLQ 302
Query: 1040 ETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLL 1098
+TC+N+QG F+C+ C Y+++S +C + C++ P I + ++ +G
Sbjct: 303 QTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPA--ENPGCRDQPFTILYRDMDVVSGRS 360
Query: 1099 VPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDV 1158
VPA IF++ + G I GNE F R+ + + + R + PR+ LD+
Sbjct: 361 VPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDL 420
Query: 1159 EM 1160
EM
Sbjct: 421 EM 422
Score = 167 bits (424), Expect = 4e-41
Identities = 109/336 (32%), Positives = 149/336 (44%), Gaps = 72/336 (21%)
Query: 692 VCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCY----- 746
+C G+A C G+ + C DI+EC T C CVN G + C
Sbjct: 15 LCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNP 74
Query: 747 ----------------------------------KALTCEPGYAL-KDGECEDVDECAMG 771
+ L C GY + + +C DVDECA
Sbjct: 75 VYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATD 134
Query: 772 THTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFS---CI 828
+H C P +C NT+G + C C DG+ EG C+DI+E CR G+ C
Sbjct: 135 SHQCNPTQICINTEGGYTCS----CTDGYWL-LEGQCLDIDE-------CRYGYCQQLCA 182
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888
N GSY+C NP G+ ++DG C DVNEC T + C Q C N GS+ C C
Sbjct: 183 NVPGSYSCTCNP-----GFTLNEDGRSCQDVNECAT-ENPC--VQTCVNTYGSFICRCDP 234
Query: 889 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
G++ + G C D++EC S LCQH C N G+Y CSC G++L D + C+D+NECE
Sbjct: 235 GYELEEDGVHCSDMDECSFSE-FLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECE 293
Query: 949 AQ----RCSQECANIYGSYQCY----CRQGYQLAED 976
+ Q C N+ G ++C C + Y D
Sbjct: 294 HRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISD 329
Score = 149 bits (377), Expect = 1e-35
Identities = 110/345 (31%), Positives = 150/345 (43%), Gaps = 64/345 (18%)
Query: 604 DQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
D DEC +P E C+ +C+N G Y C P +P P
Sbjct: 42 DIDECRTIP-EACRGDMMCVNQNGGYLCI---------------PRTNPVY-RGPYSNPY 84
Query: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDIN 721
+ +S P P P N P T+ IC GY M + C D++
Sbjct: 85 STPYSG------PYPAAAPPLSAPNYP------TISRPLICRF--GYQ-MDESNQCVDVD 129
Query: 722 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLC 781
EC TD H C+ + C+NT G + C +C GY L +G+C D+DEC G CQ LC
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTC----SCTDGYWLLEGQCLDIDECRYG--YCQQ--LC 181
Query: 782 QNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNP 840
N GS+ C C GF + +G +C D+NEC + PC +C+NT GS+ C+
Sbjct: 182 ANVPGSYSC----TCNPGFTLNEDGRSCQDVNECAT-ENPCVQ--TCVNTYGSFICR--- 231
Query: 841 LICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
C GY +DG C D++EC C C N PG+Y C C G+ R C
Sbjct: 232 --CDPGYELEEDGVHCSDMDECSFSEFLC--QHECVNQPGTYFCSCPPGYILLDDNRSCQ 287
Query: 901 DVNECWASPGRLC--QHTCENTLGSYRC----SCASGFLLAADGK 939
D+NEC C Q TC N G ++C C +L +D +
Sbjct: 288 DINEC-EHRNHTCNLQQTCYNLQGGFKCIDPIRCEEPYLRISDNR 331
Score = 128 bits (321), Expect = 4e-29
Identities = 74/221 (33%), Positives = 95/221 (42%), Gaps = 48/221 (21%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC CQ LC N GSY C C PGF+L +DGR+C+
Sbjct: 168 DIDECRY---GYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQ------------------ 206
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
N C PC Q C GS IC C PGY + DGV C D++EC
Sbjct: 207 ---------------DVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDEC 251
Query: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLC 781
C CVN G++ C +C PGY L D C+D++EC HTC C
Sbjct: 252 SFSEFLCQ--HECVNQPGTYFC----SCPPGYILLDDNRSCQDINECEHRNHTCNLQQTC 305
Query: 782 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCR 822
N +G F C RC + +L+ + C+ C + + CR
Sbjct: 306 YNLQGGFKCIDPIRCEEPYLRISDNRCM----CPAENPGCR 342
Score = 121 bits (304), Expect = 3e-27
Identities = 91/295 (30%), Positives = 129/295 (43%), Gaps = 57/295 (19%)
Query: 568 PEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ--HLCINTVG 625
P PAAAP + L ++ S D DEC C +CINT G
Sbjct: 91 PYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECAT-DSHQCNPTQICINTEG 149
Query: 626 SYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKD 685
Y C+C G+ L L+ + + + C+
Sbjct: 150 GYTCSCTDGYWL-----------------------LEGQCLDI------------DECR- 173
Query: 686 NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHC 745
G C+Q+C+ V GS C+C PG+ + DG SC+D+NEC T+ + C + CVNT GSF C
Sbjct: 174 YGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-NPCV--QTCVNTYGSFIC 230
Query: 746 YKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQ 802
C+PGY L++ C D+DEC+ CQ C N G+++C C G+ L
Sbjct: 231 ----RCDPGYELEEDGVHCSDMDECSFSEFLCQ--HECVNQPGTYFCS----CPPGYILL 280
Query: 803 DPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY-HASDDGTKC 856
D +C DINEC + C +C N G + C +P+ C Y SD+ C
Sbjct: 281 DDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC-IDPIRCEEPYLRISDNRCMC 334
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 259 bits (663), Expect = 8e-69
Identities = 185/488 (37%), Positives = 236/488 (48%), Gaps = 46/488 (9%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT--CRPEGHPPQPE------- 654
D +ECL P + + CIN VGSY C C+PG++L G T C+ QP
Sbjct: 887 DDNECLRDPCK-GKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQC 945
Query: 655 APQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAIC-SCFPGYAIMA 712
E + E Q N C+ G C C GS C +C GY
Sbjct: 946 TNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGY--RG 1003
Query: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAM 770
SC D+NEC+T C+ G+ C N GSF C +CE GY + E C+DVDECA
Sbjct: 1004 QSGSCVDVNECLTP-GVCAHGK-CTNLEGSFRC----SCEQGYEVTSDEKGCQDVDECA- 1056
Query: 771 GTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCIN 829
+C G LC NT+GSF C A C +G+ + +G C D++EC + C P C N
Sbjct: 1057 SRASCPTG-LCLNTEGSFACSA---CENGYWVNEDGTACEDLDEC-AFPGVC-PSGVCTN 1110
Query: 830 TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAG 889
T GS++C+ C GY S G C DV+ECE C G+ C N GSY+C C G
Sbjct: 1111 TAGSFSCKD----CDGGYRPSPLGDSCEDVDECEDPQSSCLGGE-CKNTVGSYQCLCPQG 1165
Query: 890 FQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA 949
FQ A G C DVNEC C N+ GS+ C CA GF+ A G C+DV+EC
Sbjct: 1166 FQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECAT 1224
Query: 950 QR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQ 1006
C N GS+ C C G+Q + + C DIDEC +C T++C N PGSY+
Sbjct: 1225 TDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYR 1284
Query: 1007 CACP-EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL---RFECPPN-YV 1061
C + G+ M NG C D+DECA T C C N GSFRCL FE P+ +
Sbjct: 1285 CVLGCQPGFHMAPNG-DCIDIDECANDT-MCGSHGFCDNTDGSFRCLCDQGFEISPSGWD 1342
Query: 1062 QVSKTKCE 1069
V +CE
Sbjct: 1343 CVDVNECE 1350
Score = 248 bits (634), Expect = 2e-65
Identities = 179/534 (33%), Positives = 241/534 (45%), Gaps = 58/534 (10%)
Query: 567 PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELC-QHLCINTVG 625
PP P + E E ++ T+ + S PG D+ C +C C+N
Sbjct: 815 PPMPEQGIAEIQE------EQVTPSTDVLVTLSTPGIDR--CAAGATNVCGPGTCVNLPD 866
Query: 626 SYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQ----------VASNTIPL 675
Y C C PG+ L C + + + + +A++
Sbjct: 867 GYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQ 926
Query: 676 PLPQPNTCKDNGPCK-QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGE 734
N C+ G C C+ GS C C GY ++ G C+DINEC TC G
Sbjct: 927 ECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HCQDINEC-RHPGTCPDG- 983
Query: 735 HCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQ 794
CVN+ GS+ C L CE GY + G C DV+EC + C G C N +GSF C
Sbjct: 984 RCVNSPGSYTC---LACEEGYRGQSGSCVDVNEC-LTPGVCAHG-KCTNLEGSFRCS--- 1035
Query: 795 RCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 853
C G+ + E C D++EC S + C G C+NT GS+ C C GY ++DG
Sbjct: 1036 -CEQGYEVTSDEKGCQDVDECASRAS-CPTGL-CLNTEGSFACS----ACENGYWVNEDG 1088
Query: 854 TKCVDVNECE-TGVHRCGEGQVCHNLPGSYRC-DCKAGFQRDAFGRGCIDVNECWASPGR 911
T C D++EC GV C G VC N GS+ C DC G++ G C DV+EC
Sbjct: 1089 TACEDLDECAFPGV--CPSG-VCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSS 1145
Query: 912 LCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA-QRCSQ--ECANIYGSYQCYCR 968
C+NT+GSY+C C GF L A+G CEDVNEC + C+ EC N +GS+ C C
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQL-ANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCA 1204
Query: 969 QGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1028
G+ AE G +C D+DECA C+N GS+ C C E G+ + C D+DE
Sbjct: 1205 PGFVSAEGGTSCQDVDECAT-TDPCVGGHCVNTEGSFNCLC-ETGFQPSPESGECVDIDE 1262
Query: 1029 CA-LGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQN 1081
C G C + C N GS+RC+ C P + C D EC N
Sbjct: 1263 CEDYGDPVCGTWK-CENSPGSYRCV-LGCQPGF-----HMAPNGDCIDIDECAN 1309
Score = 248 bits (632), Expect = 3e-65
Identities = 195/596 (32%), Positives = 264/596 (44%), Gaps = 98/596 (16%)
Query: 516 KQCCDCCGLGLRVRAEGQSCESNPNLG---------------YPCNHVMLSCCEGEEPLI 560
KQ C C +G +A G CE P G Y + + LS + EE
Sbjct: 693 KQICCCSRVG---KAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEE-- 747
Query: 561 VPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLC 620
E+ RPP + A R+ L + T+ L D D G++
Sbjct: 748 --ELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDS---QAGQV----- 797
Query: 621 INTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNT---IPLPL 677
T H + G+ P P++ + + QV +T + L
Sbjct: 798 --TTSVTHAPAWV-------------TGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLST 842
Query: 678 PQPNTCKDN-----GPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSR 732
P + C GP C + C C PGY + C D NEC+ D C
Sbjct: 843 PGIDRCAAGATNVCGP--GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRD--PCKG 898
Query: 733 GEHCVNTLGSFHCYKALTCEPGYALKDG----ECEDVDECAMGTHTCQPGFLCQNTKGSF 788
C+N +GS+ C+ C PGY L EC+D++EC C G C NT+GS+
Sbjct: 899 KGRCINRVGSYSCF----CYPGYTLATSGATQECQDINECEQ-PGVCSGG-QCTNTEGSY 952
Query: 789 YCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYH 848
+C+ C G++ +G+C DINEC C P C+N+ GSYTC L C GY
Sbjct: 953 HCE----CDQGYIMVRKGHCQDINECRH-PGTC-PDGRCVNSPGSYTC----LACEEGYR 1002
Query: 849 ASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 907
CVDVNEC T GV C G+ C NL GS+RC C+ G++ + +GC DV+EC A
Sbjct: 1003 GQSG--SCVDVNECLTPGV--CAHGK-CTNLEGSFRCSCEQGYEVTSDEKGCQDVDEC-A 1056
Query: 908 SPGRLCQHTCENTLGSYRCS-CASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQ 964
S C NT GS+ CS C +G+ + DG CED++EC S C N GS+
Sbjct: 1057 SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFS 1116
Query: 965 CY-CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C C GY+ + G +C D+DEC C N GSYQC CP QG+ + ANG C
Sbjct: 1117 CKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCP-QGFQL-ANGTVC 1174
Query: 1024 KDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
+DV+EC +G +C+ C N GSF CL C P +V T+C D EC
Sbjct: 1175 EDVNEC-MGEEHCAPHGECLNSHGSFFCL---CAPGFVSAE----GGTSCQDVDEC 1222
Score = 247 bits (630), Expect = 5e-65
Identities = 171/470 (36%), Positives = 230/470 (48%), Gaps = 49/470 (10%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT-----CRPEGHPPQPEAPQE 658
D +EC PG C NT GSYHC C G+ + G CR G P
Sbjct: 930 DINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNS 988
Query: 659 P------ALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIM 711
P A + + + + + + N C G C C+ + GS CSC GY +
Sbjct: 989 PGSYTCLACEEGYRGQSGSCVDV-----NECLTPGVCAHGKCTNLEGSFRCSCEQGYEVT 1043
Query: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDGE-CEDVDECA 769
+D C+D++EC + +C G C+NT GSF C CE GY + +DG CED+DECA
Sbjct: 1044 SDEKGCQDVDECASRA-SCPTGL-CLNTEGSFACS---ACENGYWVNEDGTACEDLDECA 1098
Query: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCI 828
C G +C NT GSF C+ C G+ P G+ C D++EC C G C
Sbjct: 1099 F-PGVCPSG-VCTNTAGSFSCKD---CDGGYRPSPLGDSCEDVDECEDPQSSCLGG-ECK 1152
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888
NTVGSY C +C +G+ ++ GT C DVNEC G C C N GS+ C C
Sbjct: 1153 NTVGSYQC-----LCPQGFQLAN-GTVCEDVNEC-MGEEHCAPHGECLNSHGSFFCLCAP 1205
Query: 889 GFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
GF G C DV+EC + + H C NT GS+ C C +GF + + C D++ECE
Sbjct: 1206 GFVSAEGGTSCQDVDECATTDPCVGGH-CVNTEGSFNCLCETGFQPSPESGECVDIDECE 1264
Query: 949 AQR---CSQ-ECANIYGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVP 1002
C +C N GSY+C C+ G+ +A +G C DIDECA C N
Sbjct: 1265 DYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTD 1323
Query: 1003 GSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
GS++C C +QG+ ++ +G C DV+EC L C A C N++GSF CL
Sbjct: 1324 GSFRCLC-DQGFEISPSGWDCVDVNECELMLAVCGAA-LCENVEGSFLCL 1371
Score = 222 bits (565), Expect = 2e-57
Identities = 219/796 (27%), Positives = 303/796 (38%), Gaps = 169/796 (21%)
Query: 277 SEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARP 336
+EEEE RE+ G R LP A P + + EAG + G
Sbjct: 744 AEEEELARPPREQ----------GQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKG--- 790
Query: 337 EENLILDAQATSRSTGPEGVTHAPS--LGKAAL--VPTQAVPGSPRDPVKPSPHNILSTS 392
D+QA +T VTHAP+ G A +P Q + + V PS +++ S
Sbjct: 791 ------DSQAGQVTTS---VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLS 841
Query: 393 LPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQ- 451
P + P + ++P D C+ G Q
Sbjct: 842 TPGIDRCA--------------AGATNVCGPGTCVNLP---------DGYRCVCSPGYQL 878
Query: 452 -----WAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAED 506
+ D++ECL P G + R C C G A G T +D
Sbjct: 879 HPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCF--------CYPGYTLATSGATQECQD 930
Query: 507 NDSC---GISLYKQC--------CDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG 555
+ C G+ QC C+C + VR +G + N C H
Sbjct: 931 INECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR-KGHCQDINE-----CRH-------- 976
Query: 556 EEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGEL 615
P P+ R P + E G+ + D +ECL PG
Sbjct: 977 --PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV-------------DVNECLT-PGVC 1020
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C N GS+ C+C G+ + D + C+
Sbjct: 1021 AHGKCTNLEGSFRCSCEQGYEVTSDEKGCQ------------------------------ 1050
Query: 676 PLPQPNTCKDNGPCKQ-VCSTVGGSAICS-CFPGYAIMADGVSCEDINECVTDLHTCSRG 733
+ C C +C GS CS C GY + DG +CED++EC C G
Sbjct: 1051 ---DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFP-GVCPSG 1106
Query: 734 EHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 791
C NT GSF C C+ GY CEDVDEC +C G C+NT GS+ C
Sbjct: 1107 V-CTNTAGSFSCKD---CDGGYRPSPLGDSCEDVDECEDPQSSCLGGE-CKNTVGSYQCL 1161
Query: 792 ARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASD 851
C GF C D+NEC E C P C+N+ GS+ C +CA G+ +++
Sbjct: 1162 ----CPQGFQLANGTVCEDVNECMG-EEHCAPHGECLNSHGSFFC-----LCAPGFVSAE 1211
Query: 852 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 911
GT C DV+EC T C G C N GS+ C C+ GFQ C+D++EC
Sbjct: 1212 GGTSCQDVDECAT-TDPCVGGH-CVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDP 1269
Query: 912 LC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEAQR-CSQE--CANIYGSYQC 965
+C CEN+ GSYRC C GF +A +G C D++EC C C N GS++C
Sbjct: 1270 VCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-CIDIDECANDTMCGSHGFCDNTDGSFRC 1328
Query: 966 YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKD 1025
C QG++++ G C D++EC + C NV GS+ C C A C+
Sbjct: 1329 LCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCR- 1387
Query: 1026 VDECALGTHNCSEAET 1041
G + SEA T
Sbjct: 1388 --PRGAGGQSMSEAPT 1401
Score = 69.3 bits (168), Expect = 2e-11
Identities = 38/90 (42%), Positives = 45/90 (50%), Gaps = 11/90 (12%)
Query: 855 KCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC--WASPGRL 912
+C +N CE G C + Y CDC GFQ DA C+DVNEC P L
Sbjct: 1736 ECGILNGCENGR--------CVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVL 1787
Query: 913 CQH-TCENTLGSYRCSCASGFLLAADGKRC 941
C H CENT GSYRC C+ G++ A C
Sbjct: 1788 CVHGYCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 53.5 bits (127), Expect = 1e-06
Identities = 76/317 (23%), Positives = 109/317 (34%), Gaps = 56/317 (17%)
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
+D DEC L E + C+NT GS+HC C P +L + C + + +
Sbjct: 1527 EDHDECQDLACENGE--CVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMD 1584
Query: 663 SEFSQVASNTIPLPLPQPNT------CKDNGPCKQVC------STVGGSAICSCFPGYAI 710
+ +V ++ PL T C+D Q C S+ + +C+ A
Sbjct: 1585 ICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAE 1644
Query: 711 MADGVSCE---DINECVTDLHTCSRGEHCV---NTLGSFHCYKALTCEPGYALKDGECED 764
GV + DLH G N LG + EP + G D
Sbjct: 1645 REAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGP----EDTVPEPAFPNTAGHSAD 1700
Query: 765 ---VDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE-GNCVDINECTSLSEP 820
+ E + QP ++ + + + Q G L E G CV + E
Sbjct: 1701 RTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVRE------- 1753
Query: 821 CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET---GVHRCGEGQVCHN 877
YTC C G+ CVDVNEC+ C G C N
Sbjct: 1754 ------------GYTCD-----CFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG-YCEN 1795
Query: 878 LPGSYRCDCKAGFQRDA 894
GSYRC C G+ +A
Sbjct: 1796 TEGSYRCHCSPGYVAEA 1812
Score = 52.4 bits (124), Expect = 3e-06
Identities = 48/161 (29%), Positives = 63/161 (39%), Gaps = 35/161 (21%)
Query: 633 PGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTI----PLPLPQPNTCKDNGP 688
PG SL D G PP+P P P + + NT+ PL + T +D
Sbjct: 519 PGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQED--- 575
Query: 689 CKQVCSTVGG------SAICSCFPGYAIMADG-------------VSCEDINECVTDLHT 729
C +VG A C P ++ +G C+DINEC+T L
Sbjct: 576 ---CCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLT-LGL 631
Query: 730 CSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAM 770
C E CVNT GS+ C TC PG L V + A+
Sbjct: 632 CKDAE-CVNTRGSYLC----TCRPGLMLDPSRSRCVSDKAI 667
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 939 KRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQGAGILCTF 996
+ C +N CE RC + Y C C +G+QL C D++EC G +LC
Sbjct: 1735 EECGILNGCENGRC----VRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH 1790
Query: 997 -RCLNVPGSYQCACPEQGYTMTANGRSC 1023
C N GSY+C C GY A C
Sbjct: 1791 GYCENTEGSYRCHC-SPGYVAEAGPPHC 1817
Score = 48.5 bits (114), Expect = 4e-05
Identities = 32/85 (37%), Positives = 39/85 (45%), Gaps = 10/85 (11%)
Query: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECE-----AQRCS 953
+ EC G C++ C Y C C GF L A C DVNEC+ A C
Sbjct: 1732 LQAEECGILNG--CENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCV 1789
Query: 954 Q-ECANIYGSYQCYCRQGYQLAEDG 977
C N GSY+C+C GY +AE G
Sbjct: 1790 HGYCENTEGSYRCHCSPGY-VAEAG 1813
Score = 48.5 bits (114), Expect = 4e-05
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 15/84 (17%)
Query: 681 NTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLH----TCSRGEHC 736
N C +NG C +V C CF G+ + A ++C D+NEC DL+ C G +C
Sbjct: 1741 NGC-ENGRCVRVRE----GYTCDCFEGFQLDAAHMACVDVNEC-DDLNGPAVLCVHG-YC 1793
Query: 737 VNTLGSFHCYKALTCEPGYALKDG 760
NT GS+ C+ C PGY + G
Sbjct: 1794 ENTEGSYRCH----CSPGYVAEAG 1813
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 16/95 (16%)
Query: 766 DECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEP---C 821
+EC + + C+ G C + + C C +GF D CVD+NEC L+ P C
Sbjct: 1735 EECGI-LNGCENG-RCVRVREGYTCD----CFEGFQLDAAHMACVDVNECDDLNGPAVLC 1788
Query: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
G+ C NT GSY C C+ GY A C
Sbjct: 1789 VHGY-CENTEGSYRCH-----CSPGYVAEAGPPHC 1817
Score = 41.6 bits (96), Expect = 0.005
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 14/139 (10%)
Query: 816 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVC 875
+L PC P S + L C +GY + T C D+NEC T + C + + C
Sbjct: 587 TLCAPCPP------RPASPVIENGQLECPQGYKRLNL-THCQDINECLT-LGLCKDAE-C 637
Query: 876 HNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLA 935
N GSY C C+ G D C+ + Q C +LG C+ +
Sbjct: 638 VNTRGSYLCTCRPGLMLDPSRSRCVSDKAI-----SMLQGLCYRSLGPGTCTLPLAQRIT 692
Query: 936 ADGKRCEDVNECEAQRCSQ 954
C V + C +
Sbjct: 693 KQICCCSRVGKAWGSECEK 711
Score = 41.6 bits (96), Expect = 0.005
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 980 CTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC--ALGTHNCS 1037
C ++ C G RC+ V Y C C E G+ + A +C DV+EC G
Sbjct: 1737 CGILNGCENG-------RCVRVREGYTCDCFE-GFQLDAAHMACVDVNECDDLNGPAVLC 1788
Query: 1038 EAETCHNIQGSFRCLRFECPPNYV 1061
C N +GS+RC C P YV
Sbjct: 1789 VHGYCENTEGSYRC---HCSPGYV 1809
Score = 36.6 bits (83), Expect = 0.15
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 7/72 (9%)
Query: 941 CEDVNECEAQRCSQ--ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC 998
C+D+NEC + EC N GSY C CR G L C + G+ C
Sbjct: 620 CQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGL-----C 674
Query: 999 LNVPGSYQCACP 1010
G C P
Sbjct: 675 YRSLGPGTCTLP 686
Score = 35.0 bits (79), Expect = 0.42
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 604 DQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTC 644
D +ECL L LC+ C+NT GSY C C PG L C
Sbjct: 622 DINECLTLG--LCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Score = 34.7 bits (78), Expect = 0.55
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 14/67 (20%)
Query: 798 DGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHAS 850
+G L+ P+G +C DINEC +L C+ C+NT GSY C C G
Sbjct: 603 NGQLECPQGYKRLNLTHCQDINECLTLG-LCKDA-ECVNTRGSYLC-----TCRPGLMLD 655
Query: 851 DDGTKCV 857
++CV
Sbjct: 656 PSRSRCV 662
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 249 bits (635), Expect = 1e-65
Identities = 197/614 (32%), Positives = 280/614 (45%), Gaps = 87/614 (14%)
Query: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 695 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 750
Query: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 751 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 810
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 811 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 860
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDI 720
S SQV + P + + N C N C + C C+ GY C DI
Sbjct: 861 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 917
Query: 721 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG-ECEDVDECAMGTHTCQPG 778
+EC H CS+G C NT GSF C C G+ A ++G C DVDEC + C G
Sbjct: 918 DECTQVQHLCSQGR-CENTEGSFLCI----CPAGFMASEEGTNCIDVDEC-LRPDVCGEG 971
Query: 779 FLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQR 838
C NT G+F C+ C G+ G C DI+EC L+ P C+N+ GSY C
Sbjct: 972 H-CVNTVGAFRCEY---CDSGYRMTQRGRCEDIDEC--LNPSTCPDEQCVNSPGSYQC-- 1023
Query: 839 NPLICARGYHASDDGTKCVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGR 897
+ C G+ + +C+DV+EC E V C G C NL GSY C C G+ R +
Sbjct: 1024 --VPCTEGFRGWNG--QCLDVDECLEPNV--CANGD-CSNLEGSYMCSCHKGYTRTPDHK 1076
Query: 898 GCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQ- 954
C D++EC G LC + C+NT GS+RC+C G+ L+A +CED++EC+ + C+
Sbjct: 1077 HCRDIDEC--QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHG 1134
Query: 955 ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
+C N GS+QC C QGY+ + G C DI+EC + + C+N GSY C CP+ G+
Sbjct: 1135 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPD-GF 1193
Query: 1015 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCH 1074
+ N ++C+D++EC C C N +GSF C+ C + + TC
Sbjct: 1194 QLDDN-KTCQDINECE-HPGLCGPQGECLNTEGSFHCV---CQQGF----SISADGRTCE 1244
Query: 1075 DFLECQNSPARITH 1088
D EC N+ +H
Sbjct: 1245 DIDECVNNTVCDSH 1258
Score = 217 bits (553), Expect = 5e-56
Identities = 157/481 (32%), Positives = 216/481 (44%), Gaps = 72/481 (14%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP---- 659
D DEC + Q C NT GS+ C C GF ++G C +P+ E
Sbjct: 916 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN 975
Query: 660 ---ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--------KQVCSTVGGSAICSCFPGY 708
A + E+ + Q C+D C +Q ++ G C G+
Sbjct: 976 TVGAFRCEYCDSGYR-----MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF 1030
Query: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD 766
C D++EC+ + + C+ G+ C N GS+ C +C GY C D+D
Sbjct: 1031 R--GWNGQCLDVDECL-EPNVCANGD-CSNLEGSYMC----SCHKGYTRTPDHKHCRDID 1082
Query: 767 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGF 825
EC G + C G C+NT+GSF C C G+ L + C DI+EC C G
Sbjct: 1083 ECQQG-NLCVNG-QCKNTEGSFRCT----CGQGYQLSAAKDQCEDIDECQH-RHLCAHG- 1134
Query: 826 SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD 885
C NT GS+ C +C +GY AS G C D+NEC C G C N GSY C
Sbjct: 1135 QCRNTEGSFQC-----VCDQGYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCT 1188
Query: 886 CKAGFQRDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRCSCASGFLLAADGKRCED 943
C GFQ D + C D+NEC PG LC Q C NT GS+ C C GF ++ADG+ CED
Sbjct: 1189 CPDGFQLDD-NKTCQDINEC-EHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 1245
Query: 944 VNECEAQRCSQE---CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLN 1000
++EC C N GS++C C QG+Q +DG C D++EC +G+ C N
Sbjct: 1246 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 1305
Query: 1001 VPGSYQCACPEQGYTMTANGRSCK-------DVD---------ECALGTHNCSEAETCHN 1044
V GS+ C C ++ + C+ DVD EC +N ++A C N
Sbjct: 1306 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKEC---YYNLNDASLCDN 1362
Query: 1045 I 1045
+
Sbjct: 1363 V 1363
Score = 142 bits (359), Expect = 1e-33
Identities = 191/749 (25%), Positives = 257/749 (34%), Gaps = 219/749 (29%)
Query: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 1034 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 1088
Query: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 1089 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 1148
Query: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCIN 622
+ G A LG E D +ECL + CIN
Sbjct: 1149 Q--------------------GYRASGLGDHCE--------DINECLEDKSVCQRGDCIN 1180
Query: 623 TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
T GSY C C GF L DD +TC+ N
Sbjct: 1181 TAGSYDCTCPDGFQL-DDNKTCQ---------------------------------DINE 1206
Query: 683 CKDNGPC--KQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTL 740
C+ G C + C GS C C G++I ADG +CEDI+ECV + C C NT
Sbjct: 1207 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTA 1265
Query: 741 GSFHCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYC-------- 790
GSF C C G+ A +DG+ C DV+EC + + C F C+N +GSF C
Sbjct: 1266 GSFRCL----CYQGFQAPQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCADENQE 1320
Query: 791 ------QARQRC---MDGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSY 834
Q R R +D + P+ N D + C ++ P C T G+
Sbjct: 1321 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1380
Query: 835 ---TCQRNPL----------ICARGY--------HASDDGTKCVDVNECET-GVHRCGEG 872
C+ P +C +G + G D +EC G C G
Sbjct: 1381 WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG 1440
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
+ PG Y C CK G D C D++EC P C NT GSY C C
Sbjct: 1441 FCLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPM 1498
Query: 933 LLAADGKRC-------EDVNECEAQR------------CSQECANIYGSY-QCYCRQGYQ 972
+L A KRC E + E + + CS+ +Y +C C G
Sbjct: 1499 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1558
Query: 973 LAEDGHTC--TDIDECAQGAGILCTFR--------------------------------- 997
C D D+ AQ I T R
Sbjct: 1559 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1618
Query: 998 ------------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN---C 1036
C+ V Y C C + GY + +C DV+EC + C
Sbjct: 1619 EELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNECDELNNRMSLC 1677
Query: 1037 SEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
A+ C N GS++CL C P YV K
Sbjct: 1678 KNAK-CINTDGSYKCL---CLPGYVPSDK 1702
Score = 70.1 bits (170), Expect = 1e-11
Identities = 112/488 (22%), Positives = 161/488 (32%), Gaps = 127/488 (26%)
Query: 603 DDQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTC---------------- 644
+D DEC+ +C C NT GS+ C C+ GF DG+ C
Sbjct: 1244 EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 1301
Query: 645 ---RPEGH-------PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC----KDNGPC- 689
EG Q +P +S S + P + C D C
Sbjct: 1302 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1361
Query: 690 --------KQVCSTVGGSAI---CSCFP-----------------GY------AIMADGV 715
KQ C G+ C FP G+ + A G
Sbjct: 1362 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1421
Query: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG--YALKDGECEDVDECAMGTH 773
+ +D +EC+ + C+NT + CY C+ G Y +C D+DEC
Sbjct: 1422 NYKDADECLLFGQEICKNGFCLNTRPGYECY----CKQGTYYDPVKLQCFDMDEC-QDPS 1476
Query: 774 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV-------DINECTSLSEPCRPGFS 826
+C G C NT+GS+ C + L E C+ I E + C S
Sbjct: 1477 SCIDG-QCVNTEGSYNCFCTHPMV---LDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1532
Query: 827 CINTVGSYTCQRNPLI----------CARG-----------YHASDDGTKCVDVNECETG 865
Y C R PL+ C G SDD + ++ TG
Sbjct: 1533 -----DEYVCSR-PLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPV--TG 1584
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC--IDVNECWASPGRLCQH-TCENTLG 922
+ + Y + F +D F + EC G C++ C
Sbjct: 1585 RRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG--CENGRCVRVQE 1642
Query: 923 SYRCSCASGFLLAADGKRCEDVNECEAQR-----CSQ-ECANIYGSYQCYCRQGYQLAED 976
Y C C G+ L C DVNEC+ C +C N GSY+C C GY ++
Sbjct: 1643 GYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDK 1702
Query: 977 GHTCTDID 984
+ CT ++
Sbjct: 1703 PNYCTPLN 1710
Score = 69.3 bits (168), Expect = 2e-11
Identities = 123/583 (21%), Positives = 193/583 (33%), Gaps = 113/583 (19%)
Query: 424 NSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSY 483
N+ S + P+G D +TC D +EC G + T CV
Sbjct: 1180 NTAGSYDCTCPDGFQLDDNKTCQ--------DINECEHPGLCGPQGECLNTEGSFHCV-- 1229
Query: 484 LQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDC--------------CGLGLRVR 529
C G + +G TC ED D C + CD C G +
Sbjct: 1230 -----CQQGFSISADGRTC--EDIDEC---VNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 1279
Query: 530 AEGQSCESNPN---LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGRE 586
+GQ C L C EG + + + P M G+
Sbjct: 1280 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP-----------MTGQC 1328
Query: 587 ALSLGTEAELPNSLPGDDQDECL--LLPGELCQHLCINTVGSYHCACFPGFSLQDD---- 640
T+ ++ P +++ EC L LC ++ V C C G D+
Sbjct: 1329 RSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF 1388
Query: 641 ----------GRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
C P+G P E + A + L CK+
Sbjct: 1389 PCPVLGTAEFTEMC-PKGKGFVPAGESSSEAGGENYKDADECL---LFGQEICKNG---- 1440
Query: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCY---- 746
C C C G + C D++EC D +C G+ CVNT GS++C+
Sbjct: 1441 -FCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQ-CVNTEGSYNCFCTHP 1497
Query: 747 KALTCEPGYALKDGEC-EDVDECAMGTHTC----QPGFLCQNT---KGSFYCQARQRCMD 798
L ++ E E ++E + C ++C K + Y + C+
Sbjct: 1498 MVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC--CLY 1555
Query: 799 GFLQDPEGNCVDINECTSLSEPCRPGFS----------CINTVGSYTCQRNPLICARGYH 848
G + + + ++ C + ++ YT + +P +
Sbjct: 1556 GEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFL 1615
Query: 849 ASDD---GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 905
S + +C +N CE G C + Y CDC G+ D C+DVNEC
Sbjct: 1616 NSFEELQAEECGILNGCENGR--------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC 1667
Query: 906 WASPGR--LCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVN 945
R LC++ C NT GSY+C C G++ + C +N
Sbjct: 1668 DELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 823 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 863
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 573 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 631
Query: 864 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 912
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 632 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 688
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCE 942
C H L C C+ G A G CE
Sbjct: 689 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 715
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKA 748
C + S G + + C PGY + C+DINEC C GE C+NT+GS+ C
Sbjct: 597 CPKKPSYHGYNQMMECLPGYK-RVNNTFCQDINECQLQ-GVCPNGE-CLNTMGSYRC--- 650
Query: 749 LTCEPGY 755
TC+ G+
Sbjct: 651 -TCKIGF 656
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 739 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 798
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 563 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 614
Query: 799 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 857
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 615 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 666
Score = 39.3 bits (90), Expect = 0.022
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 863 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 922
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 562 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 610
Query: 923 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 971
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 611 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 37.4 bits (85), Expect = 0.085
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 907 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 966
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 571 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 611
Query: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1009
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 612 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 652
Score = 34.7 bits (78), Expect = 0.55
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 626 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 682
Query: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
S + + + + L + C K GP + C G +A PG
Sbjct: 683 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 731
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 249 bits (635), Expect = 1e-65
Identities = 197/614 (32%), Positives = 280/614 (45%), Gaps = 87/614 (14%)
Query: 512 ISLYKQCCDCCGLGLRVRAEGQSCESNP-------------NLGYPCNHVM----LSCCE 554
+ L KQ C CC +G +A G CE P +GY + V +
Sbjct: 369 VHLTKQLC-CCSVG---KAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHV 424
Query: 555 GEEPLIV-PEVRRP------PEPAAAPRRVSEAEMAGREALSLGTEAELPNS-----LPG 602
G+ P+ V P+ +P P P A EA RE E E+ + +P
Sbjct: 425 GKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPS 484
Query: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
DQ++ L PG+ I+T+ + FPG ++ PP P A
Sbjct: 485 LDQEKTKLEPGQPQLSPGISTIHLH--PQFPGIVIEKTS--------PPVPVEVAPEAST 534
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQV--CSTVGGSAICSCFPGYAIMADGVSCEDI 720
S SQV + P + + N C N C + C C+ GY C DI
Sbjct: 535 SSASQVIA---PTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI 591
Query: 721 NECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDG-ECEDVDECAMGTHTCQPG 778
+EC H CS+G C NT GSF C C G+ A ++G C DVDEC + C G
Sbjct: 592 DECTQVQHLCSQGR-CENTEGSFLCI----CPAGFMASEEGTNCIDVDEC-LRPDVCGEG 645
Query: 779 FLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQR 838
C NT G+F C+ C G+ G C DI+EC L+ P C+N+ GSY C
Sbjct: 646 H-CVNTVGAFRCEY---CDSGYRMTQRGRCEDIDEC--LNPSTCPDEQCVNSPGSYQC-- 697
Query: 839 NPLICARGYHASDDGTKCVDVNEC-ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGR 897
+ C G+ + +C+DV+EC E V C G C NL GSY C C G+ R +
Sbjct: 698 --VPCTEGFRGWNG--QCLDVDECLEPNV--CANGD-CSNLEGSYMCSCHKGYTRTPDHK 750
Query: 898 GCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR-CSQ- 954
C D++EC G LC + C+NT GS+RC+C G+ L+A +CED++EC+ + C+
Sbjct: 751 HCRDIDEC--QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHG 808
Query: 955 ECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
+C N GS+QC C QGY+ + G C DI+EC + + C+N GSY C CP+ G+
Sbjct: 809 QCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPD-GF 867
Query: 1015 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCH 1074
+ N ++C+D++EC C C N +GSF C+ C + + TC
Sbjct: 868 QLDDN-KTCQDINECE-HPGLCGPQGECLNTEGSFHCV---CQQGF----SISADGRTCE 918
Query: 1075 DFLECQNSPARITH 1088
D EC N+ +H
Sbjct: 919 DIDECVNNTVCDSH 932
Score = 217 bits (553), Expect = 5e-56
Identities = 157/481 (32%), Positives = 216/481 (44%), Gaps = 72/481 (14%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEP---- 659
D DEC + Q C NT GS+ C C GF ++G C +P+ E
Sbjct: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVN 649
Query: 660 ---ALKSEFSQVASNTIPLPLPQPNTCKDNGPC--------KQVCSTVGGSAICSCFPGY 708
A + E+ + Q C+D C +Q ++ G C G+
Sbjct: 650 TVGAFRCEYCDSGYR-----MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF 704
Query: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD 766
C D++EC+ + + C+ G+ C N GS+ C +C GY C D+D
Sbjct: 705 R--GWNGQCLDVDECL-EPNVCANGD-CSNLEGSYMC----SCHKGYTRTPDHKHCRDID 756
Query: 767 ECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGF 825
EC G + C G C+NT+GSF C C G+ L + C DI+EC C G
Sbjct: 757 ECQQG-NLCVNG-QCKNTEGSFRCT----CGQGYQLSAAKDQCEDIDECQH-RHLCAHG- 808
Query: 826 SCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD 885
C NT GS+ C +C +GY AS G C D+NEC C G C N GSY C
Sbjct: 809 QCRNTEGSFQC-----VCDQGYRASGLGDHCEDINECLEDKSVCQRGD-CINTAGSYDCT 862
Query: 886 CKAGFQRDAFGRGCIDVNECWASPGRLC--QHTCENTLGSYRCSCASGFLLAADGKRCED 943
C GFQ D + C D+NEC PG LC Q C NT GS+ C C GF ++ADG+ CED
Sbjct: 863 CPDGFQLDD-NKTCQDINEC-EHPG-LCGPQGECLNTEGSFHCVCQQGFSISADGRTCED 919
Query: 944 VNECEAQRCSQE---CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLN 1000
++EC C N GS++C C QG+Q +DG C D++EC +G+ C N
Sbjct: 920 IDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCEN 979
Query: 1001 VPGSYQCACPEQGYTMTANGRSCK-------DVD---------ECALGTHNCSEAETCHN 1044
V GS+ C C ++ + C+ DVD EC +N ++A C N
Sbjct: 980 VEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKEC---YYNLNDASLCDN 1036
Query: 1045 I 1045
+
Sbjct: 1037 V 1037
Score = 142 bits (359), Expect = 1e-33
Identities = 191/749 (25%), Positives = 257/749 (34%), Gaps = 219/749 (29%)
Query: 456 NDECLEIPESGTEDNVCRTAQ-RHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC---G 511
N +CL++ E E NVC + SY+ SC G + + C D D C
Sbjct: 708 NGQCLDVDEC-LEPNVCANGDCSNLEGSYMC--SCHKGYTRTPDHKHC--RDIDECQQGN 762
Query: 512 ISLYKQCCDC-------CGLGLRVRAEGQSCESNPNLGYP--CNHVMLSCCEGEEPLIVP 562
+ + QC + CG G ++ A CE + C H EG +
Sbjct: 763 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCD 822
Query: 563 EVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCIN 622
+ G A LG E D +ECL + CIN
Sbjct: 823 Q--------------------GYRASGLGDHCE--------DINECLEDKSVCQRGDCIN 854
Query: 623 TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
T GSY C C GF L DD +TC+ N
Sbjct: 855 TAGSYDCTCPDGFQL-DDNKTCQ---------------------------------DINE 880
Query: 683 CKDNGPC--KQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTL 740
C+ G C + C GS C C G++I ADG +CEDI+ECV + C C NT
Sbjct: 881 CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNT-VCDSHGFCDNTA 939
Query: 741 GSFHCYKALTCEPGY-ALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYC-------- 790
GSF C C G+ A +DG+ C DV+EC + + C F C+N +GSF C
Sbjct: 940 GSFRCL----CYQGFQAPQDGQGCVDVNECELLSGVCGEAF-CENVEGSFLCVCADENQE 994
Query: 791 ------QARQRC---MDGFLQDPEG-------NCVDINECTSLSEPCRPGFSCINTVGSY 834
Q R R +D + P+ N D + C ++ P C T G+
Sbjct: 995 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAG 1054
Query: 835 ---TCQRNPL----------ICARGY--------HASDDGTKCVDVNECET-GVHRCGEG 872
C+ P +C +G + G D +EC G C G
Sbjct: 1055 WGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNG 1114
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGF 932
+ PG Y C CK G D C D++EC P C NT GSY C C
Sbjct: 1115 FCLNTRPG-YECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPM 1172
Query: 933 LLAADGKRC-------EDVNECEAQR------------CSQECANIYGSY-QCYCRQGYQ 972
+L A KRC E + E + + CS+ +Y +C C G
Sbjct: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEA 1232
Query: 973 LAEDGHTC--TDIDECAQGAGILCTFR--------------------------------- 997
C D D+ AQ I T R
Sbjct: 1233 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1292
Query: 998 ------------------CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN---C 1036
C+ V Y C C + GY + +C DV+EC + C
Sbjct: 1293 EELQAEECGILNGCENGRCVRVQEGYTCDCFD-GYHLDTAKMTCVDVNECDELNNRMSLC 1351
Query: 1037 SEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
A+ C N GS++CL C P YV K
Sbjct: 1352 KNAK-CINTDGSYKCL---CLPGYVPSDK 1376
Score = 70.1 bits (170), Expect = 1e-11
Identities = 112/488 (22%), Positives = 161/488 (32%), Gaps = 127/488 (26%)
Query: 603 DDQDECLLLPGELCQH--LCINTVGSYHCACFPGFSLQDDGRTC---------------- 644
+D DEC+ +C C NT GS+ C C+ GF DG+ C
Sbjct: 918 EDIDECV--NNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEA 975
Query: 645 ---RPEGH-------PPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC----KDNGPC- 689
EG Q +P +S S + P + C D C
Sbjct: 976 FCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD 1035
Query: 690 --------KQVCSTVGGSAI---CSCFP-----------------GY------AIMADGV 715
KQ C G+ C FP G+ + A G
Sbjct: 1036 NVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGE 1095
Query: 716 SCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG--YALKDGECEDVDECAMGTH 773
+ +D +EC+ + C+NT + CY C+ G Y +C D+DEC
Sbjct: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECY----CKQGTYYDPVKLQCFDMDEC-QDPS 1150
Query: 774 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV-------DINECTSLSEPCRPGFS 826
+C G C NT+GS+ C + L E C+ I E + C S
Sbjct: 1151 SCIDG-QCVNTEGSYNCFCTHPMV---LDASEKRCIRPAESNEQIEETDVYQDLCWEHLS 1206
Query: 827 CINTVGSYTCQRNPLI----------CARG-----------YHASDDGTKCVDVNECETG 865
Y C R PL+ C G SDD + ++ TG
Sbjct: 1207 -----DEYVCSR-PLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPV--TG 1258
Query: 866 VHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC--IDVNECWASPGRLCQH-TCENTLG 922
+ + Y + F +D F + EC G C++ C
Sbjct: 1259 RRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNG--CENGRCVRVQE 1316
Query: 923 SYRCSCASGFLLAADGKRCEDVNECEAQR-----CSQ-ECANIYGSYQCYCRQGYQLAED 976
Y C C G+ L C DVNEC+ C +C N GSY+C C GY ++
Sbjct: 1317 GYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDK 1376
Query: 977 GHTCTDID 984
+ CT ++
Sbjct: 1377 PNYCTPLN 1384
Score = 69.3 bits (168), Expect = 2e-11
Identities = 123/583 (21%), Positives = 193/583 (33%), Gaps = 113/583 (19%)
Query: 424 NSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSY 483
N+ S + P+G D +TC D +EC G + T CV
Sbjct: 854 NTAGSYDCTCPDGFQLDDNKTCQ--------DINECEHPGLCGPQGECLNTEGSFHCV-- 903
Query: 484 LQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDC--------------CGLGLRVR 529
C G + +G TC ED D C + CD C G +
Sbjct: 904 -----CQQGFSISADGRTC--EDIDEC---VNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
Query: 530 AEGQSCESNPN---LGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGRE 586
+GQ C L C EG + + + P M G+
Sbjct: 954 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP-----------MTGQC 1002
Query: 587 ALSLGTEAELPNSLPGDDQDECL--LLPGELCQHLCINTVGSYHCACFPGFSLQDD---- 640
T+ ++ P +++ EC L LC ++ V C C G D+
Sbjct: 1003 RSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF 1062
Query: 641 ----------GRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
C P+G P E + A + L CK+
Sbjct: 1063 PCPVLGTAEFTEMC-PKGKGFVPAGESSSEAGGENYKDADECL---LFGQEICKNG---- 1114
Query: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCY---- 746
C C C G + C D++EC D +C G+ CVNT GS++C+
Sbjct: 1115 -FCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCIDGQ-CVNTEGSYNCFCTHP 1171
Query: 747 KALTCEPGYALKDGEC-EDVDECAMGTHTC----QPGFLCQNT---KGSFYCQARQRCMD 798
L ++ E E ++E + C ++C K + Y + C+
Sbjct: 1172 MVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC--CLY 1229
Query: 799 GFLQDPEGNCVDINECTSLSEPCRPGFS----------CINTVGSYTCQRNPLICARGYH 848
G + + + ++ C + ++ YT + +P +
Sbjct: 1230 GEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFL 1289
Query: 849 ASDD---GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC 905
S + +C +N CE G C + Y CDC G+ D C+DVNEC
Sbjct: 1290 NSFEELQAEECGILNGCENGR--------CVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC 1341
Query: 906 WASPGR--LCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVN 945
R LC++ C NT GSY+C C G++ + C +N
Sbjct: 1342 DELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 37/150 (24%)
Query: 823 PGFS----CINTVGSY----TCQRNP-----------LICARGYHASDDGTKCVDVNECE 863
PG S C TVG+ CQ+ P + C GY ++ T C D+NEC+
Sbjct: 247 PGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN-TFCQDINECQ 305
Query: 864 T-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI--------DVNECW--ASPGRL 912
GV C G+ C N GSYRC CK GF D C+ + C+ S GR
Sbjct: 306 LQGV--CPNGE-CLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQ 362
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCE 942
C H L C C+ G A G CE
Sbjct: 363 CMHPLSVHLTKQLCCCSVG---KAWGPHCE 389
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query: 689 CKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKA 748
C + S G + + C PGY + C+DINEC C GE C+NT+GS+ C
Sbjct: 271 CPKKPSYHGYNQMMECLPGYK-RVNNTFCQDINECQLQ-GVCPNGE-CLNTMGSYRC--- 324
Query: 749 LTCEPGY 755
TC+ G+
Sbjct: 325 -TCKIGF 330
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 15/119 (12%)
Query: 739 TLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMD 798
T+GS C KAL PG + ++ C V + G + CQ C C+
Sbjct: 237 TIGS-QCGKAL---PGLSKQEDCCGTVGT-SWGFNKCQK---CPKKPSYHGYNQMMECLP 288
Query: 799 GFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCV 857
G+ + C DINEC L C P C+NT+GSY C C G+ + CV
Sbjct: 289 GYKRVNNTFCQDINEC-QLQGVC-PNGECLNTMGSYRC-----TCKIGFGPDPTFSSCV 340
Score = 39.3 bits (90), Expect = 0.022
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 863 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLG 922
ET +CG+ LPG + + G ++G N+C P + H +
Sbjct: 236 ETIGSQCGKA-----LPGLSKQEDCCGTVGTSWG-----FNKCQKCPKKPSYHGYNQMM- 284
Query: 923 SYRCSCASGFLLAADGKRCEDVNECEAQRC--SQECANIYGSYQCYCRQGY 971
C G+ + C+D+NEC+ Q + EC N GSY+C C+ G+
Sbjct: 285 ----ECLPGYK-RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.4 bits (85), Expect = 0.085
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 21/103 (20%)
Query: 907 ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCY 966
A PG Q C T+G+ + GF N+C Q+C ++ + +
Sbjct: 245 ALPGLSKQEDCCGTVGT-----SWGF------------NKC--QKCPKKPSYHGYNQMME 285
Query: 967 CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCAC 1009
C GY+ + C DI+EC Q G+ CLN GSY+C C
Sbjct: 286 CLPGYKRVNNTF-CQDINEC-QLQGVCPNGECLNTMGSYRCTC 326
Score = 34.7 bits (78), Expect = 0.55
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 8/109 (7%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D +EC L G C+NT+GSY C C GF +C P+ PP + P +
Sbjct: 300 DINECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD--PPVISEEKGPCYRL 356
Query: 664 EFS-QVASNTIPLPLPQPNTC----KDNGPCKQVCSTVGGSAICSCFPG 707
S + + + + L + C K GP + C G +A PG
Sbjct: 357 VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPG 405
>gi|86788132 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 761 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 810
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 811 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 844
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 845 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 904
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 905 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 963
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 964 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1024 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1083 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1142
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1143 YLQRAVLEPRDFALDVEM 1160
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 118 bits (295), Expect = 4e-26
Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 47/220 (21%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC + P C C+NT GS++C C PGF L + TC
Sbjct: 214 DIDECTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTC------------------- 252
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
N C + C Q C + GS IC C GY + +D ++CEDI+EC
Sbjct: 253 --------------VDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDEC 298
Query: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMGTHTCQPGFLCQ 782
T + C CVN G F C C GY ++ C+D++EC T+ C+ +C
Sbjct: 299 RTSSYLCQ--YQCVNEPGKFSC----MCPQGYQVVRSRTCQDINECET-TNECREDEMCW 351
Query: 783 NTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCR 822
N G F C R C D ++ PE CV C + CR
Sbjct: 352 NYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAMCR 387
>gi|86788015 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 761 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 810
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 811 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 844
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 845 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 904
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 905 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 963
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 964 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1024 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1083 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1142
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1143 YLQRAVLEPRDFALDVEM 1160
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 118 bits (295), Expect = 4e-26
Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 47/220 (21%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC + P C C+NT GS++C C PGF L + TC
Sbjct: 214 DIDECTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTC------------------- 252
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
N C + C Q C + GS IC C GY + +D ++CEDI+EC
Sbjct: 253 --------------VDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDEC 298
Query: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMGTHTCQPGFLCQ 782
T + C CVN G F C C GY ++ C+D++EC T+ C+ +C
Sbjct: 299 RTSSYLCQ--YQCVNEPGKFSC----MCPQGYQVVRSRTCQDINECET-TNECREDEMCW 351
Query: 783 NTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCR 822
N G F C R C D ++ PE CV C + CR
Sbjct: 352 NYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAMCR 387
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein 1
precursor [Homo sapiens]
Length = 493
Score = 243 bits (620), Expect = 8e-64
Identities = 139/438 (31%), Positives = 214/438 (48%), Gaps = 49/438 (11%)
Query: 761 ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPE----------GNCVD 810
+C+D+DEC + C+ G C N G + C + + + P+ G
Sbjct: 41 QCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTG 100
Query: 811 INECTSLSEP-CRPGFSCINTVGS------------YTCQRNP-------------LICA 844
+ +S++ PG + + + + +RNP + CA
Sbjct: 101 VVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCA 160
Query: 845 RGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNE 904
GY S+ C D++EC G H C QVC NL GS+ C C G+Q+ G C+D++E
Sbjct: 161 AGYEQSEHNV-CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKR--GEQCVDIDE 217
Query: 905 CWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQ-RCSQECANIYGSY 963
C P C C NT GS+ C C+ GF LAA+ C D+NEC+A +C+Q+C NI GS+
Sbjct: 218 CTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSF 275
Query: 964 QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
C C QGY+L+ D C DIDEC + + LC ++C+N PG + C CP QGY R+C
Sbjct: 276 ICQCNQGYELSSDRLNCEDIDEC-RTSSYLCQYQCVNEPGKFSCMCP-QGY-QVVRSRTC 332
Query: 1024 KDVDECALGTHNCSEAETCHNIQGSFRCL-RFECPPNYVQVSKTKCERTTCHDFLECQNS 1082
+D++EC T+ C E E C N G FRC R C Y+ + +C + C+
Sbjct: 333 QDINECET-TNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAM--CREL 389
Query: 1083 PARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVV 1142
P I + ++ ++ VP+ IF+I + I GNE G F R+ + + ++
Sbjct: 390 PQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAML 449
Query: 1143 YLQRAVLEPRDFALDVEM 1160
L +++ PR+ +D+EM
Sbjct: 450 VLVKSLSGPREHIVDLEM 467
Score = 118 bits (295), Expect = 4e-26
Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 47/220 (21%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKS 663
D DEC + P C C+NT GS++C C PGF L + TC
Sbjct: 214 DIDECTIPP--YCHQRCVNTPGSFYCQCSPGFQLAANNYTC------------------- 252
Query: 664 EFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINEC 723
N C + C Q C + GS IC C GY + +D ++CEDI+EC
Sbjct: 253 --------------VDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDEC 298
Query: 724 VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY-ALKDGECEDVDECAMGTHTCQPGFLCQ 782
T + C CVN G F C C GY ++ C+D++EC T+ C+ +C
Sbjct: 299 RTSSYLCQ--YQCVNEPGKFSC----MCPQGYQVVRSRTCQDINECET-TNECREDEMCW 351
Query: 783 NTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCR 822
N G F C R C D ++ PE CV C + CR
Sbjct: 352 NYHGGFRCYPRNPCQDPYILTPENRCV----CPVSNAMCR 387
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 219 bits (559), Expect = 9e-57
Identities = 144/463 (31%), Positives = 196/463 (42%), Gaps = 67/463 (14%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C H CIN GSY C C G+ L D TCR
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRI----------------------------- 279
Query: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH 735
Q ++ C+Q+C V GS +C C+ GYA+ DG C ++ C ++ H C
Sbjct: 280 ---QDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE--HE 334
Query: 736 CVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 793
CVN GS+ C C G+AL + C +D CA H CQ C NT S+ C
Sbjct: 335 CVNADGSYLC----QCHEGFALNPDKKTCTKIDYCASSNHGCQ--HECVNTDDSYSC--- 385
Query: 794 QRCMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
C+ GF +P+ C IN C C C+N SY C+ C RGY +
Sbjct: 386 -HCLKGFTLNPDKKTCRRINYCALNKPGCE--HECVNMEESYYCR-----CHRGYTLDPN 437
Query: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
G C V+ C H C Q+C N S+ C C GF + + C V+ C S
Sbjct: 438 GKTCSRVDHCAQQDHGC--EQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLS-DHG 494
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQG 970
C+++C N S+ C C G +L +DGK C ++ C C C + S+ C C +G
Sbjct: 495 CEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 554
Query: 971 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECA 1030
Y L EDG TC D C Q C C+N SY C C E G+ + +G+ C+ D C
Sbjct: 555 YILREDGKTCRRKDVC-QAIDHGCEHICVNSDDSYTCECLE-GFRLAEDGKRCRRKDVCK 612
Query: 1031 LGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK-TKCERTT 1072
H C C N S+ C +C +V +C++ T
Sbjct: 613 STHHGCE--HICVNNGNSYIC---KCSEGFVLAEDGRRCKKCT 650
Score = 204 bits (518), Expect = 5e-52
Identities = 127/429 (29%), Positives = 185/429 (43%), Gaps = 62/429 (14%)
Query: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
QD C + C+ LC+N GS+ C C+ G++L +DG+ C
Sbjct: 280 QDLCAM-EDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------- 318
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECV 724
+ +N C+ C GS +C C G+A+ D +C I+ C
Sbjct: 319 ------------VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 725 TDLHTCSRGEHCVNTLGSF--HCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQ 782
+ H C CVNT S+ HC K T P C ++ CA+ C+ C
Sbjct: 367 SSNHGCQ--HECVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCE--HECV 418
Query: 783 NTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
N + S+YC RC G+ DP G C ++ C C C+NT S+ CQ
Sbjct: 419 NMEESYYC----RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ---- 468
Query: 842 ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
C+ G+ ++D C V+ C H C C N+ S+ C C G + G+ C
Sbjct: 469 -CSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAK 525
Query: 902 VNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQECANI 959
++ C A C+H+C ++ S+ C C G++L DGK C + C+A C C N
Sbjct: 526 LDSC-ALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNS 584
Query: 960 YGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTAN 1019
SY C C +G++LAEDG C D C + C C+N SY C C E G+ + +
Sbjct: 585 DDSYTCECLEGFRLAEDGKRCRRKDVC-KSTHHGCEHICVNNGNSYICKCSE-GFVLAED 642
Query: 1020 GRSCKDVDE 1028
GR CK E
Sbjct: 643 GRRCKKCTE 651
Score = 57.8 bits (138), Expect = 6e-08
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 34/113 (30%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C+H+C+N+ SY C C GF L +DG+ CR
Sbjct: 577 CEHICVNSDDSYTCECLEGFRLAEDGKRCR------------------------------ 606
Query: 676 PLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDL 727
+ + CK + C+ +C G S IC C G+ + DG C+ E DL
Sbjct: 607 ---RKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 219 bits (559), Expect = 9e-57
Identities = 144/463 (31%), Positives = 196/463 (42%), Gaps = 67/463 (14%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C H CIN GSY C C G+ L D TCR
Sbjct: 249 CAHFCINIPGSYVCRCKQGYILNSDQTTCRI----------------------------- 279
Query: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH 735
Q ++ C+Q+C V GS +C C+ GYA+ DG C ++ C ++ H C
Sbjct: 280 ---QDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCE--HE 334
Query: 736 CVNTLGSFHCYKALTCEPGYALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQAR 793
CVN GS+ C C G+AL + C +D CA H CQ C NT S+ C
Sbjct: 335 CVNADGSYLC----QCHEGFALNPDKKTCTKIDYCASSNHGCQ--HECVNTDDSYSC--- 385
Query: 794 QRCMDGFLQDPE-GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
C+ GF +P+ C IN C C C+N SY C+ C RGY +
Sbjct: 386 -HCLKGFTLNPDKKTCRRINYCALNKPGCE--HECVNMEESYYCR-----CHRGYTLDPN 437
Query: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
G C V+ C H C Q+C N S+ C C GF + + C V+ C S
Sbjct: 438 GKTCSRVDHCAQQDHGC--EQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLS-DHG 494
Query: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQECANIYGSYQCYCRQG 970
C+++C N S+ C C G +L +DGK C ++ C C C + S+ C C +G
Sbjct: 495 CEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEG 554
Query: 971 YQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECA 1030
Y L EDG TC D C Q C C+N SY C C E G+ + +G+ C+ D C
Sbjct: 555 YILREDGKTCRRKDVC-QAIDHGCEHICVNSDDSYTCECLE-GFRLAEDGKRCRRKDVCK 612
Query: 1031 LGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK-TKCERTT 1072
H C C N S+ C +C +V +C++ T
Sbjct: 613 STHHGCE--HICVNNGNSYIC---KCSEGFVLAEDGRRCKKCT 650
Score = 204 bits (518), Expect = 5e-52
Identities = 127/429 (29%), Positives = 185/429 (43%), Gaps = 62/429 (14%)
Query: 605 QDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
QD C + C+ LC+N GS+ C C+ G++L +DG+ C
Sbjct: 280 QDLCAM-EDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC-------------------- 318
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECV 724
+ +N C+ C GS +C C G+A+ D +C I+ C
Sbjct: 319 ------------VAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCA 366
Query: 725 TDLHTCSRGEHCVNTLGSF--HCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQ 782
+ H C CVNT S+ HC K T P C ++ CA+ C+ C
Sbjct: 367 SSNHGCQ--HECVNTDDSYSCHCLKGFTLNP----DKKTCRRINYCALNKPGCE--HECV 418
Query: 783 NTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 841
N + S+YC RC G+ DP G C ++ C C C+NT S+ CQ
Sbjct: 419 NMEESYYC----RCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQ---- 468
Query: 842 ICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCID 901
C+ G+ ++D C V+ C H C C N+ S+ C C G + G+ C
Sbjct: 469 -CSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAK 525
Query: 902 VNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEA--QRCSQECANI 959
++ C A C+H+C ++ S+ C C G++L DGK C + C+A C C N
Sbjct: 526 LDSC-ALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNS 584
Query: 960 YGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTAN 1019
SY C C +G++LAEDG C D C + C C+N SY C C E G+ + +
Sbjct: 585 DDSYTCECLEGFRLAEDGKRCRRKDVC-KSTHHGCEHICVNNGNSYICKCSE-GFVLAED 642
Query: 1020 GRSCKDVDE 1028
GR CK E
Sbjct: 643 GRRCKKCTE 651
Score = 57.8 bits (138), Expect = 6e-08
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 34/113 (30%)
Query: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
C+H+C+N+ SY C C GF L +DG+ CR
Sbjct: 577 CEHICVNSDDSYTCECLEGFRLAEDGKRCR------------------------------ 606
Query: 676 PLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDL 727
+ + CK + C+ +C G S IC C G+ + DG C+ E DL
Sbjct: 607 ---RKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDL 656
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 209 bits (533), Expect = 1e-53
Identities = 132/338 (39%), Positives = 173/338 (51%), Gaps = 35/338 (10%)
Query: 702 CSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH-CVNTLGSFHCYKALTCEPGYALKDG 760
C C PGY C D+NEC + C G C+NT GS++C+ C GY L G
Sbjct: 599 CHCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICMNTGGSYNCH----CNRGYRLHVG 652
Query: 761 ----ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINEC 814
C D++ECA H C G C N G + C C G+ C DI+EC
Sbjct: 653 AGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKC----NCYPGYRLKASRPPVCEDIDEC 707
Query: 815 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 874
S C P C N GS+ C + C GY S G C DVNEC G C G
Sbjct: 708 RDPSS-C-PDGKCENKPGSFKC----IACQPGYR-SQGGGACRDVNECAEG-SPCSPGW- 758
Query: 875 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFL 933
C NLPGS+RC C G+ GR C+DV+EC A G +C + C NT GS++C C SG+
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQCQCLSGYH 816
Query: 934 LAADGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 991
L+ D CED++EC+ A +C N GSY+C C QG++L G C DIDEC+Q
Sbjct: 817 LSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPS 875
Query: 992 I-LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1028
+ L C N+ GSY C C ++G+T T + C++V++
Sbjct: 876 LCLPHGACKNLQGSYVCVC-DEGFTPTQDQHGCEEVEQ 912
Score = 200 bits (508), Expect = 8e-51
Identities = 124/338 (36%), Positives = 159/338 (47%), Gaps = 67/338 (19%)
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 822
+ DEC + + C G C + C C G+ P+ CVD+NEC + EPC
Sbjct: 574 ETDECRLNQNICGHGE-CVPGPPDYSCH----CNPGYRSHPQHRYCVDVNECEA--EPCG 626
Query: 823 PGFS-CINTVGSYTCQRNPLICARGY--HASDDGTKCVDVNECETGVHRCGEGQVCHNLP 879
PG C+NT GSY C C RGY H G CVD+NEC H CG+G C N P
Sbjct: 627 PGRGICMNTGGSYNCH-----CNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFP 680
Query: 880 GSYRCDCKAGFQ------------------------------------------RDAFGR 897
G Y+C+C G++ R G
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 898 GCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE- 955
C DVNEC + G C CEN GS+RC+CA G+ A DG+ C DV+ECEA
Sbjct: 741 ACRDVNEC--AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 956 -CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
C+N GS+QC C GY L+ D C DIDEC A + C+N GSY+C CP QG+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCP-QGH 856
Query: 1015 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
+ GR C+D+DEC+ C C N+QGS+ C+
Sbjct: 857 RL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Score = 189 bits (480), Expect = 1e-47
Identities = 165/514 (32%), Positives = 212/514 (41%), Gaps = 71/514 (13%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ--DDGRTCRPEGHPPQPEAPQEPAL 661
D +EC P + +C+NT GSY+C C G+ L GR+C +P +
Sbjct: 616 DVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGF 675
Query: 662 KSEF-SQVASNTIP---LPLPQPNTCKDNGPCKQV-------CSTVGGSAIC-SCFPGYA 709
F N P L +P C+D C+ C GS C +C PGY
Sbjct: 676 CINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 710 IMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGE-CEDVDE 767
G +C D+NEC CS G C N GSF C TC GYA DG C DVDE
Sbjct: 736 SQGGG-ACRDVNECAEG-SPCSPG-WCENLPGSFRC----TCAQGYAPAPDGRSCLDVDE 788
Query: 768 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFS 826
C G C G +C NT GSF CQ C+ G+ L +C DI+EC C G
Sbjct: 789 CEAGD-VCDNG-ICSNTPGSFQCQ----CLSGYHLSRDRSHCEDIDEC-DFPAACIGG-D 840
Query: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
CINT GSY C +C +G H G KC D++EC C C NL GSY C C
Sbjct: 841 CINTNGSYRC-----LCPQG-HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVC 894
Query: 887 KAGFQRDAFGRGCIDV------NECWAS--PGRLCQHTCENTLGSYRCSCASGFLLAADG 938
GF GC +V EC+ + C + C C+ G A G
Sbjct: 895 DEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWG 951
Query: 939 KRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCT-------DIDECAQ-GA 990
CE + C ++ + C G +D + DIDEC G+
Sbjct: 952 DHCE-IYPCPVYSSAE--------FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGS 1002
Query: 991 GILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFR 1050
I +C+N Y+C C +QG+ N C DVDEC L NC C N +G +R
Sbjct: 1003 EICKEGKCVNTQPGYECYC-KQGFYYDGNLLECVDVDEC-LDESNCRNG-VCENTRGGYR 1059
Query: 1051 CLRFECPPNYVQVSKTKCERTTCHDFLECQNSPA 1084
C PP ++ +C D ECQ+ A
Sbjct: 1060 CAC--TPPAEYSPAQRQCLSPEEMDVDECQDPAA 1091
Score = 144 bits (362), Expect = 6e-34
Identities = 200/842 (23%), Positives = 285/842 (33%), Gaps = 208/842 (24%)
Query: 377 PRDPVKPSPHNILSTSLPDA-AWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPE 435
P P KP LP++ + PP + + V S V E+ H ++P
Sbjct: 484 PDGPPKPQ-------QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPA 536
Query: 436 GSTKDLIETCCAAGQQWAIDN----DECLEI-PESGTEDNVCRTAQRHC----CVSYLQE 486
+LI +W + + +EI P TE + CR Q C CV +
Sbjct: 537 RPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPD 596
Query: 487 KSCMAGV-------------LGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
SC + E E CG C G L V A G+
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 656
Query: 534 SCE-----SNPNL----GYPCN---HVMLSCCEG-----EEPLIVPEVRRPPEPAAAPRR 576
SC + P+L G+ N H +C G P + ++ +P++ P
Sbjct: 657 SCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 577 VSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGF 635
E + + ++ D +EC G C C N GS+ C C G+
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGY 774
Query: 636 SLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTC---------KDN 686
+ DGR+C + E V N I P C +D
Sbjct: 775 APAPDGRSCLDVD-------------ECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDR 821
Query: 687 GPCKQV-------------CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG 733
C+ + C GS C C G+ ++ G C+DI+EC D C
Sbjct: 822 SHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPH 880
Query: 734 EHCVNTLGSFHCYKALTCEPGYALKDGE--CEDVD------EC------------AMGTH 773
C N GS+ C C+ G+ + CE+V+ EC + T+
Sbjct: 881 GACKNLQGSYVC----VCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN 936
Query: 774 TCQPGFLCQNTKG-SFYCQA-----------RQRCMDGFLQDPEGNCV--------DINE 813
Q C G +C+ C DG + N V DI+E
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDE 996
Query: 814 CTSL-SEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEG 872
C SE C+ G C+NT Y C C +G++ + +CVDV+EC C G
Sbjct: 997 CMLFGSEICKEG-KCVNTQPGYECY-----CKQGFYYDGNLLECVDVDEC-LDESNCRNG 1049
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCI-----DVNECWASPGRLCQHTCENTLGSYRCS 927
VC N G YRC C + R C+ DV+EC P C N GSYRC
Sbjct: 1050 -VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC-QDPAACRPGRCVNLPGSYRCE 1107
Query: 928 CASGFLLAADGKRC-----------EDVNECEAQR-----CSQECANIYGSYQ-CYCRQG 970
C ++ G+ C E + C +QR C+ A ++ C CRQG
Sbjct: 1108 CRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1167
Query: 971 YQLAEDGHTCT--------------------------------------DIDECAQGAGI 992
C D DEC +G
Sbjct: 1168 RGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSG- 1226
Query: 993 LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHN--CSEAETCHNIQGSFR 1050
RC+ PG C CP G+ + A+ C D+DEC ++E C N GSFR
Sbjct: 1227 ----RCVPRPGGAVCECPG-GFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFR 1281
Query: 1051 CL 1052
C+
Sbjct: 1282 CV 1283
Score = 138 bits (348), Expect = 3e-32
Identities = 143/496 (28%), Positives = 198/496 (39%), Gaps = 67/496 (13%)
Query: 598 NSLPGDDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAP 656
NS D +EC + PG +C+H C+N GSY C C P GH P
Sbjct: 349 NSTHCQDINECAM-PG-VCRHGDCLNNPGSYRCVC--------------PPGHSLGPSRT 392
Query: 657 QEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVS 716
Q A K E + + C+ +T +C C G A G
Sbjct: 393 QCIADKPEEKSLCFRLV----------SPEHQCQHPLTTRLTRQLCCCSVGKAW---GAR 439
Query: 717 CEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQ 776
C+ C TD T + E C G Y LT ++ GE + ++ H
Sbjct: 440 CQ---RCPTD-GTAAFKEICPAGKG----YHILTSHQTLTIQ-GE----SDFSLFLHPDG 486
Query: 777 PGFLCQNTKGSFYCQARQRCMD--GFLQDP---EGNCVDINECTSLSEPCRPGFSCINTV 831
P Q + + + G D E V + T+ + P RP I+
Sbjct: 487 PPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRP 546
Query: 832 GSYTCQRN-PLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
T + P + T+ + +EC + CG G+ C P Y C C G+
Sbjct: 547 SPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGE-CVPGPPDYSCHCNPGY 605
Query: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL--AADGKRCEDVNECE 948
+ R C+DVNEC A P + C NT GSY C C G+ L A G+ C D+NEC
Sbjct: 606 RSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA 665
Query: 949 AQRCSQE---CANIYGSYQCYCRQGYQL-AEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1004
+ C N G Y+C C GY+L A C DIDEC + +C N PGS
Sbjct: 666 KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGS 724
Query: 1005 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1064
++C + GY + G +C+DV+ECA G+ CS C N+ GSFRC C Y
Sbjct: 725 FKCIACQPGY-RSQGGGACRDVNECAEGS-PCSPG-WCENLPGSFRC---TCAQGYAPAP 778
Query: 1065 KTKCERTTCHDFLECQ 1080
+ +C D EC+
Sbjct: 779 ----DGRSCLDVDECE 790
Score = 103 bits (257), Expect = 1e-21
Identities = 123/458 (26%), Positives = 173/458 (37%), Gaps = 107/458 (23%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC P H C N GSY C C GF+ D C QP +E L
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCE---EVEQPHHKKECYLN 922
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCFPGYA--- 709
+ + + + + Q C G PC V S+ ++C GY
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP-VYSSAEFHSLCPDGKGYTQDN 981
Query: 710 -IMADGVSCE-DINECVT-DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECE 763
I+ G+ DI+EC+ C G+ CVNT + CY C+ G+ DG EC
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGK-CVNTQPGYECY----CKQGFYY-DGNLLECV 1035
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQ---------ARQRCMDGFLQDPEGNCVDINEC 814
DVDEC + C+ G +C+NT+G + C A+++C+ PE +D++EC
Sbjct: 1036 DVDEC-LDESNCRNG-VCENTRGGYRCACTPPAEYSPAQRQCLS-----PEE--MDVDEC 1086
Query: 815 TSLSEPCRPGFSCINTVGSYTCQ-RNPLI-------CARGYHASDDGTKCVDVNECETGV 866
+ CRPG C+N GSY C+ R P + C ++ + DV + G
Sbjct: 1087 QDPAA-CRPG-RCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGE 1144
Query: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI-------------------------- 900
G + C C+ G A R C
Sbjct: 1145 DGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLL 1204
Query: 901 ------------DVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECE 948
D +EC GR C G C C GF L A RC D++EC
Sbjct: 1205 GKPPRDEDSSEEDSDECRCVSGR-----CVPRPGGAVCECPGGFQLDASRARCVDIDECR 1259
Query: 949 A--QR---C-SQECANIYGSYQCYCRQGYQLAEDGHTC 980
QR C S+ C N GS++C C+ G+ + C
Sbjct: 1260 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 66.6 bits (161), Expect = 1e-10
Identities = 81/356 (22%), Positives = 112/356 (31%), Gaps = 109/356 (30%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC+L E+C+ C+NT Y C C GF + C
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLEC------------------ 1034
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSC---- 717
+ C D C+ VC G C+C P C
Sbjct: 1035 ---------------VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE 1079
Query: 718 -EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD----------------- 759
D++EC D C G CVN GS+ C PG + +D
Sbjct: 1080 EMDVDEC-QDPAACRPGR-CVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDV 1137
Query: 760 ----------------GECEDVDECAMGTHT-----CQPGFLCQNTKGSFYCQARQRCMD 798
G D+C C+P C +C Q +
Sbjct: 1138 CWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRP---CPPRGAGSHCPTSQSESN 1194
Query: 799 GFL-----------QDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGY 847
F +D + + D +EC +S C P G C+ C G+
Sbjct: 1195 SFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVP------RPGGAVCE-----CPGGF 1243
Query: 848 HASDDGTKCVDVNECETGVHR---CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI 900
+CVD++EC R C + + C N GS+RC CKAGF R C+
Sbjct: 1244 QLDASRARCVDIDECRELNQRGLLC-KSERCVNTSGSFRCVCKAGFARSRPHGACV 1298
Score = 54.3 bits (129), Expect = 7e-07
Identities = 47/147 (31%), Positives = 59/147 (40%), Gaps = 24/147 (16%)
Query: 843 CARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI- 900
C +GY + T C D+NEC GV R G+ C N PGSYRC C G CI
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQCIA 396
Query: 901 ----DVNECW--ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ 954
+ + C+ SP CQH L C C+ G A G RC QRC
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG---KAWGARC--------QRCPT 445
Query: 955 ECANIYGSYQCYCRQGYQLAEDGHTCT 981
+ + C +GY + T T
Sbjct: 446 DGTAAFKEI-CPAGKGYHILTSHQTLT 471
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH-NLPGSYR---- 883
+T+ C NPL G +D + ++ H+C + Q PG R
Sbjct: 282 DTLPKQPCGSNPL---PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVG 338
Query: 884 CDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRC 941
DC G++R C D+NEC A PG +C+H C N GSYRC C G L +C
Sbjct: 339 ADCPQGYKR-LNSTHCQDINEC-AMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 954 QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQG 1013
Q+ + G C QGY+ H C DI+ECA G+ CLN PGSY+C CP G
Sbjct: 328 QKPGPVRGEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCP-PG 384
Query: 1014 YTMTANGRSC 1023
+++ + C
Sbjct: 385 HSLGPSRTQC 394
Score = 38.1 bits (87), Expect = 0.050
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1001 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
V G CP QGY N C+D++ECA+ C + C N GS+RC+ CPP +
Sbjct: 333 VRGEVGADCP-QGYKRL-NSTHCQDINECAM-PGVCRHGD-CLNNPGSYRCV---CPPGH 385
Query: 1061 -VQVSKTKC 1068
+ S+T+C
Sbjct: 386 SLGPSRTQC 394
Score = 35.0 bits (79), Expect = 0.42
Identities = 42/157 (26%), Positives = 57/157 (36%), Gaps = 26/157 (16%)
Query: 649 HPPQPEAPQEPALKSEFSQVASNTIPLPLPQPN-----TCKDNGPC------KQVCSTVG 697
HPP+ S A + LP P+P+ T K G C KQ C +
Sbjct: 234 HPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGS-- 291
Query: 698 GSAICSCFPGYAIMADGVSCEDINEC--VTDLHTCSRGEHC-VNTLGSFHCYKALTCEPG 754
+ PG D C I + H C + ++ V G C G
Sbjct: 292 -----NPLPGLTKQED--CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQG 344
Query: 755 YA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYC 790
Y L C+D++ECAM C+ G C N GS+ C
Sbjct: 345 YKRLNSTHCQDINECAM-PGVCRHGD-CLNNPGSYRC 379
Score = 34.3 bits (77), Expect = 0.72
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 604 DQDECLLLP--GELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE 647
D DEC L G LC+ C+NT GS+ C C GF+ C P+
Sbjct: 1254 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1300
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 209 bits (533), Expect = 1e-53
Identities = 132/338 (39%), Positives = 173/338 (51%), Gaps = 35/338 (10%)
Query: 702 CSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH-CVNTLGSFHCYKALTCEPGYALKDG 760
C C PGY C D+NEC + C G C+NT GS++C+ C GY L G
Sbjct: 599 CHCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICMNTGGSYNCH----CNRGYRLHVG 652
Query: 761 ----ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN--CVDINEC 814
C D++ECA H C G C N G + C C G+ C DI+EC
Sbjct: 653 AGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKC----NCYPGYRLKASRPPVCEDIDEC 707
Query: 815 TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQV 874
S C P C N GS+ C + C GY S G C DVNEC G C G
Sbjct: 708 RDPSS-C-PDGKCENKPGSFKC----IACQPGYR-SQGGGACRDVNECAEG-SPCSPGW- 758
Query: 875 CHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFL 933
C NLPGS+RC C G+ GR C+DV+EC A G +C + C NT GS++C C SG+
Sbjct: 759 CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEA--GDVCDNGICSNTPGSFQCQCLSGYH 816
Query: 934 LAADGKRCEDVNECE--AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAG 991
L+ D CED++EC+ A +C N GSY+C C QG++L G C DIDEC+Q
Sbjct: 817 LSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLV-GGRKCQDIDECSQDPS 875
Query: 992 I-LCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1028
+ L C N+ GSY C C ++G+T T + C++V++
Sbjct: 876 LCLPHGACKNLQGSYVCVC-DEGFTPTQDQHGCEEVEQ 912
Score = 200 bits (508), Expect = 8e-51
Identities = 124/338 (36%), Positives = 159/338 (47%), Gaps = 67/338 (19%)
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCR 822
+ DEC + + C G C + C C G+ P+ CVD+NEC + EPC
Sbjct: 574 ETDECRLNQNICGHGE-CVPGPPDYSCH----CNPGYRSHPQHRYCVDVNECEA--EPCG 626
Query: 823 PGFS-CINTVGSYTCQRNPLICARGY--HASDDGTKCVDVNECETGVHRCGEGQVCHNLP 879
PG C+NT GSY C C RGY H G CVD+NEC H CG+G C N P
Sbjct: 627 PGRGICMNTGGSYNCH-----CNRGYRLHVGAGGRSCVDLNECAKP-HLCGDGGFCINFP 680
Query: 880 GSYRCDCKAGFQ------------------------------------------RDAFGR 897
G Y+C+C G++ R G
Sbjct: 681 GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 898 GCIDVNECWASPGRLCQHT-CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQE- 955
C DVNEC + G C CEN GS+RC+CA G+ A DG+ C DV+ECEA
Sbjct: 741 ACRDVNEC--AEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNG 798
Query: 956 -CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGY 1014
C+N GS+QC C GY L+ D C DIDEC A + C+N GSY+C CP QG+
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGSYRCLCP-QGH 856
Query: 1015 TMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCL 1052
+ GR C+D+DEC+ C C N+QGS+ C+
Sbjct: 857 RL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV 893
Score = 185 bits (469), Expect = 3e-46
Identities = 157/481 (32%), Positives = 200/481 (41%), Gaps = 69/481 (14%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ--DDGRTCRPEGHPPQPEAPQEPAL 661
D +EC P + +C+NT GSY+C C G+ L GR+C +P +
Sbjct: 616 DVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGF 675
Query: 662 KSEF-SQVASNTIP---LPLPQPNTCKDNGPCKQV-------CSTVGGSAIC-SCFPGYA 709
F N P L +P C+D C+ C GS C +C PGY
Sbjct: 676 CINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 710 IMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGE-CEDVDE 767
G +C D+NEC CS G C N GSF C TC GYA DG C DVDE
Sbjct: 736 SQGGG-ACRDVNECAEG-SPCSPG-WCENLPGSFRC----TCAQGYAPAPDGRSCLDVDE 788
Query: 768 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFS 826
C G C G +C NT GSF CQ C+ G+ L +C DI+EC C G
Sbjct: 789 CEAGD-VCDNG-ICSNTPGSFQCQ----CLSGYHLSRDRSHCEDIDEC-DFPAACIGG-D 840
Query: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
CINT GSY C +C +G H G KC D++EC C C NL GSY C C
Sbjct: 841 CINTNGSYRC-----LCPQG-HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVC 894
Query: 887 KAGFQRDAFGRGCIDV------NECWAS--PGRLCQHTCENTLGSYRCSCASGFLLAADG 938
GF GC +V EC+ + C + C C+ G A G
Sbjct: 895 DEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLG---AGWG 951
Query: 939 KRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCT-------DIDECAQ-GA 990
CE + C ++ + C G +D + DIDEC G+
Sbjct: 952 DHCE-IYPCPVYSSAE--------FHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGS 1002
Query: 991 GILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFR 1050
I +C+N Y+C C +QG+ N C DVDEC L NC C N +G +R
Sbjct: 1003 EICKEGKCVNTQPGYECYC-KQGFYYDGNLLECVDVDEC-LDESNCRNG-VCENTRGGYR 1059
Query: 1051 C 1051
C
Sbjct: 1060 C 1060
Score = 161 bits (407), Expect = 4e-39
Identities = 199/817 (24%), Positives = 288/817 (35%), Gaps = 205/817 (25%)
Query: 377 PRDPVKPSPHNILSTSLPDA-AWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPE 435
P P KP LP++ + PP + + V S V E+ H ++P
Sbjct: 484 PDGPPKPQ-------QLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPA 536
Query: 436 GSTKDLIETCCAAGQQWAIDN----DECLEI-PESGTEDNVCRTAQRHC----CVSYLQE 486
+LI +W + + +EI P TE + CR Q C CV +
Sbjct: 537 RPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPD 596
Query: 487 KSCMAGV-------------LGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQ 533
SC + E E CG C G L V A G+
Sbjct: 597 YSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGR 656
Query: 534 SCE-----SNPNL----GYPCN---HVMLSCCEG-----EEPLIVPEVRRPPEPAAAPRR 576
SC + P+L G+ N H +C G P + ++ +P++ P
Sbjct: 657 SCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDG 716
Query: 577 VSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQH-LCINTVGSYHCACFPGF 635
E + + ++ D +EC G C C N GS+ C C G+
Sbjct: 717 KCENKPGSFKCIACQPGYRSQGGGACRDVNECA--EGSPCSPGWCENLPGSFRCTCAQGY 774
Query: 636 SLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCST 695
+ DGR+C + + + DNG +CS
Sbjct: 775 APAPDGRSC----------------------------LDVDECEAGDVCDNG----ICSN 802
Query: 696 VGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 755
GS C C GY + D CEDI+EC D G C+NT GS+ C C G+
Sbjct: 803 TPGSFQCQCLSGYHLSRDRSHCEDIDEC--DFPAACIGGDCINTNGSYRCL----CPQGH 856
Query: 756 ALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFL--QDPEGNCVDIN 812
L G +C+D+DEC+ C P C+N +GS+ C C +GF QD G C ++
Sbjct: 857 RLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCV----CDEGFTPTQDQHG-CEEVE 911
Query: 813 E----------------CTSLSEPCRPGFSCINTVGS--------YTCQRNPLICARGYH 848
+ C S+ C ++G+ Y C P+ + +H
Sbjct: 912 QPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPC---PVYSSAEFH 968
Query: 849 A-SDDGTKCV--------------DVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQR 892
+ DG D++EC G C EG+ + PG Y C CK GF
Sbjct: 969 SLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPG-YECYCKQGFYY 1027
Query: 893 DAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNE----- 946
D C+DV+EC C++ CENT G YRC+C + ++C E
Sbjct: 1028 DGNLLECVDVDECLDESN--CRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAP 1085
Query: 947 -----CEAQR-----CSQECANIYGSYQ-CYCRQGYQLAEDGHTCT-------------- 981
C +QR C+ A ++ C CRQG C
Sbjct: 1086 ERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSE 1145
Query: 982 ------------------------DIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
D DEC +G RC+ PG C CP G+ +
Sbjct: 1146 SNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSG-----RCVPRPGGAVCECPG-GFQLD 1199
Query: 1018 ANGRSCKDVDECALGTHN--CSEAETCHNIQGSFRCL 1052
A+ C D+DEC ++E C N GSFRC+
Sbjct: 1200 ASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCV 1236
Score = 138 bits (348), Expect = 3e-32
Identities = 143/496 (28%), Positives = 198/496 (39%), Gaps = 67/496 (13%)
Query: 598 NSLPGDDQDECLLLPGELCQHL-CINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAP 656
NS D +EC + PG +C+H C+N GSY C C P GH P
Sbjct: 349 NSTHCQDINECAM-PG-VCRHGDCLNNPGSYRCVC--------------PPGHSLGPSRT 392
Query: 657 QEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVS 716
Q A K E + + C+ +T +C C G A G
Sbjct: 393 QCIADKPEEKSLCFRLV----------SPEHQCQHPLTTRLTRQLCCCSVGKAW---GAR 439
Query: 717 CEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQ 776
C+ C TD T + E C G Y LT ++ GE + ++ H
Sbjct: 440 CQ---RCPTD-GTAAFKEICPAGKG----YHILTSHQTLTIQ-GE----SDFSLFLHPDG 486
Query: 777 PGFLCQNTKGSFYCQARQRCMD--GFLQDP---EGNCVDINECTSLSEPCRPGFSCINTV 831
P Q + + + G D E V + T+ + P RP I+
Sbjct: 487 PPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRP 546
Query: 832 GSYTCQRN-PLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGF 890
T + P + T+ + +EC + CG G+ C P Y C C G+
Sbjct: 547 SPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGE-CVPGPPDYSCHCNPGY 605
Query: 891 QRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLL--AADGKRCEDVNECE 948
+ R C+DVNEC A P + C NT GSY C C G+ L A G+ C D+NEC
Sbjct: 606 RSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA 665
Query: 949 AQRCSQE---CANIYGSYQCYCRQGYQL-AEDGHTCTDIDECAQGAGILCTFRCLNVPGS 1004
+ C N G Y+C C GY+L A C DIDEC + +C N PGS
Sbjct: 666 KPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-CPDGKCENKPGS 724
Query: 1005 YQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVS 1064
++C + GY + G +C+DV+ECA G+ CS C N+ GSFRC C Y
Sbjct: 725 FKCIACQPGY-RSQGGGACRDVNECAEGS-PCSPG-WCENLPGSFRC---TCAQGYAPAP 778
Query: 1065 KTKCERTTCHDFLECQ 1080
+ +C D EC+
Sbjct: 779 ----DGRSCLDVDECE 790
Score = 106 bits (264), Expect = 1e-22
Identities = 112/396 (28%), Positives = 158/396 (39%), Gaps = 87/396 (21%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC P H C N GSY C C GF+ D C QP +E L
Sbjct: 866 DIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCE---EVEQPHHKKECYLN 922
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNG----------PCKQVCSTVGGSAICSCFPGYA--- 709
+ + + + + Q C G PC V S+ ++C GY
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP-VYSSAEFHSLCPDGKGYTQDN 981
Query: 710 -IMADGVSCE-DINECVT-DLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDG---ECE 763
I+ G+ DI+EC+ C G+ CVNT + CY C+ G+ DG EC
Sbjct: 982 NIVNYGIPAHRDIDECMLFGSEICKEGK-CVNTQPGYECY----CKQGFYY-DGNLLECV 1035
Query: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQ---------ARQRCM----------------- 797
DVDEC + C+ G +C+NT+G + C A+++C+
Sbjct: 1036 DVDEC-LDESNCRNG-VCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWS 1093
Query: 798 ----DGFLQDP-EGNCVDINECT--------SLSEPCRP---GFSCINTVGSYTC--QRN 839
DG P G + ++C + PC P G C + +
Sbjct: 1094 QRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTS 1153
Query: 840 PLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGC 899
PL+ G D+ + D +EC RC G+ C PG C+C GFQ DA C
Sbjct: 1154 PLLL--GKPPRDEDSSEEDSDEC-----RCVSGR-CVPRPGGAVCECPGGFQLDASRARC 1205
Query: 900 IDVNEC--WASPGRLCQ-HTCENTLGSYRCSCASGF 932
+D++EC G LC+ C NT GS+RC C +GF
Sbjct: 1206 VDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Score = 63.5 bits (153), Expect = 1e-09
Identities = 74/310 (23%), Positives = 104/310 (33%), Gaps = 64/310 (20%)
Query: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
D DEC+L E+C+ C+NT Y C C GF + C
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLEC------------------ 1034
Query: 663 SEFSQVASNTIPLPLPQPNTCKDNGPCKQ-VCSTVGGSAICSCFPGYAIMADGVSC---E 718
+ C D C+ VC G C+C P C E
Sbjct: 1035 ---------------VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPE 1079
Query: 719 DINECVTDLHTC--SRGEH--CVNTL-GSFHCYKALTCEPGYALKDGECEDVDECAMGTH 773
++ C RGE C L G + C G +C G+H
Sbjct: 1080 EMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGW-GAQCRPCPPRGAGSH 1138
Query: 774 TCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGS 833
C Q+ SF+ + +D + + D +EC +S C P G
Sbjct: 1139 -CPTS---QSESNSFW-DTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVP------RPGG 1187
Query: 834 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHR---CGEGQVCHNLPGSYRCDCKAGF 890
C+ C G+ +CVD++EC R C + + C N GS+RC CKAGF
Sbjct: 1188 AVCE-----CPGGFQLDASRARCVDIDECRELNQRGLLC-KSERCVNTSGSFRCVCKAGF 1241
Query: 891 QRDAFGRGCI 900
R C+
Sbjct: 1242 ARSRPHGACV 1251
Score = 54.3 bits (129), Expect = 7e-07
Identities = 47/147 (31%), Positives = 59/147 (40%), Gaps = 24/147 (16%)
Query: 843 CARGYHASDDGTKCVDVNECET-GVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI- 900
C +GY + T C D+NEC GV R G+ C N PGSYRC C G CI
Sbjct: 341 CPQGYKRLNS-THCQDINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQCIA 396
Query: 901 ----DVNECW--ASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQ 954
+ + C+ SP CQH L C C+ G A G RC QRC
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVG---KAWGARC--------QRCPT 445
Query: 955 ECANIYGSYQCYCRQGYQLAEDGHTCT 981
+ + C +GY + T T
Sbjct: 446 DGTAAFKEI-CPAGKGYHILTSHQTLT 471
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCH-NLPGSYR---- 883
+T+ C NPL G +D + ++ H+C + Q PG R
Sbjct: 282 DTLPKQPCGSNPL---PGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVG 338
Query: 884 CDCKAGFQRDAFGRGCIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRC 941
DC G++R C D+NEC A PG +C+H C N GSYRC C G L +C
Sbjct: 339 ADCPQGYKR-LNSTHCQDINEC-AMPG-VCRHGDCLNNPGSYRCVCPPGHSLGPSRTQC 394
Score = 46.6 bits (109), Expect = 1e-04
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 954 QECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQG 1013
Q+ + G C QGY+ H C DI+ECA G+ CLN PGSY+C CP G
Sbjct: 328 QKPGPVRGEVGADCPQGYKRLNSTH-CQDINECAM-PGVCRHGDCLNNPGSYRCVCP-PG 384
Query: 1014 YTMTANGRSC 1023
+++ + C
Sbjct: 385 HSLGPSRTQC 394
Score = 38.1 bits (87), Expect = 0.050
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1001 VPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
V G CP QGY N C+D++ECA+ C + C N GS+RC+ CPP +
Sbjct: 333 VRGEVGADCP-QGYKRL-NSTHCQDINECAM-PGVCRHGD-CLNNPGSYRCV---CPPGH 385
Query: 1061 -VQVSKTKC 1068
+ S+T+C
Sbjct: 386 SLGPSRTQC 394
Score = 35.8 bits (81), Expect = 0.25
Identities = 58/227 (25%), Positives = 75/227 (33%), Gaps = 41/227 (18%)
Query: 454 IDNDECLEIPESGTEDNVC---RTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSC 510
+D DECL+ ES + VC R R C + L +E E E D C
Sbjct: 1035 VDVDECLD--ESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERA-PERRDVC 1091
Query: 511 ---------------GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEG 555
G +L C CC G R G C P G +H S E
Sbjct: 1092 WSQRGEDGMCAGPLAGPALTFDDC-CCRQG---RGWGAQCRPCPPRGAG-SHCPTSQSES 1146
Query: 556 EE-----PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGD------- 603
PL++ + R + + G E P D
Sbjct: 1147 NSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCV 1206
Query: 604 DQDECLLLP--GELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE 647
D DEC L G LC+ C+NT GS+ C C GF+ C P+
Sbjct: 1207 DIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQ 1253
Score = 35.0 bits (79), Expect = 0.42
Identities = 42/157 (26%), Positives = 57/157 (36%), Gaps = 26/157 (16%)
Query: 649 HPPQPEAPQEPALKSEFSQVASNTIPLPLPQPN-----TCKDNGPC------KQVCSTVG 697
HPP+ S A + LP P+P+ T K G C KQ C +
Sbjct: 234 HPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGS-- 291
Query: 698 GSAICSCFPGYAIMADGVSCEDINEC--VTDLHTCSRGEHC-VNTLGSFHCYKALTCEPG 754
+ PG D C I + H C + ++ V G C G
Sbjct: 292 -----NPLPGLTKQED--CCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQG 344
Query: 755 YA-LKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYC 790
Y L C+D++ECAM C+ G C N GS+ C
Sbjct: 345 YKRLNSTHCQDINECAM-PGVCRHGD-CLNNPGSYRC 379
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 751 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 807
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 3481
Query: 808 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 867
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 3482 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 3537
Query: 868 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 927
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 3538 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 3596
Query: 928 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 963
C G L DGK C + E Q + + A+I G SY
Sbjct: 3597 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 3655
Query: 964 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 3656 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 3710
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1076
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 3711 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 3769
Query: 1077 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1131
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 3770 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 3825
Query: 1132 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1172
R L A G VY +RA+ + L V R SV L
Sbjct: 3826 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 3866
Score = 187 bits (476), Expect = 4e-47
Identities = 123/358 (34%), Positives = 157/358 (43%), Gaps = 67/358 (18%)
Query: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
PC C G C+C G+A+ D +C D++EC D H C G+ CVN LGS+ C
Sbjct: 3453 PCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP 3512
Query: 748 ALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPE 805
C PG+ + DG CEDVDEC G C LC+NT G C C G+ +Q P
Sbjct: 3513 --DCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS----CPRGYRMQGPS 3566
Query: 806 GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETG 865
C+D+NEC L + C + C N GSY C +C G DG C T
Sbjct: 3567 LPCLDVNECLQLPKAC--AYQCHNLQGSYRC-----LCPPGQTLLRDGKAC-------TS 3612
Query: 866 VHRCGEG--QVCH------------NLPG-SY-----------------RCDCKAGFQRD 893
+ R G+ V H ++PG SY R C GF R
Sbjct: 3613 LERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQ 3672
Query: 894 AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC- 952
C D++EC LCQH C NT GSY+C C +G+ L GK C+D+NECE +
Sbjct: 3673 --NGVCTDLDECRVR--NLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIE 3728
Query: 953 ---SQECANIYGSYQCY---CRQGYQLAEDGHTC--TDIDECAQGAGILCTFRCLNVP 1002
Q C N GSYQC C Y+ TC +C G +R L +P
Sbjct: 3729 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQDCGTGGPSTLQYRLLPLP 3786
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 896
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 3422 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 3479
Query: 897 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 948
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 3480 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 3537
Query: 949 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1008
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 3538 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 3596
Query: 1009 CPEQGYTMTANGRSCKDVD 1027
CP G T+ +G++C ++
Sbjct: 3597 CP-PGQTLLRDGKACTSLE 3614
Score = 100 bits (250), Expect = 6e-21
Identities = 105/409 (25%), Positives = 143/409 (34%), Gaps = 98/409 (23%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 3375 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 3434
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT------------ 643
G D+DEC P C H C+N G + C C GF+L D R
Sbjct: 3435 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAH 3493
Query: 644 ----------------CRPEGHP----------PQPEAPQEPALKSEFSQVASNTI---- 673
C P+ P + E ++Q+ NT
Sbjct: 3494 LCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHR 3553
Query: 674 ------------PLPLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
LP N C C C + GS C C PG ++ DG +C +
Sbjct: 3554 CSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSL 3613
Query: 721 NECVTDLHTCSRGEHCVNTLG--------SFHCYKALT-------------CEPGYALKD 759
++ T S + L S+H + +L C PG+ ++
Sbjct: 3614 ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQN 3673
Query: 760 GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLS 818
G C D+DEC + + CQ C+NT+GS+ C C G+ P G NC DINEC S
Sbjct: 3674 GVCTDLDECRV-RNLCQHA--CRNTEGSYQCL----CPAGYRLLPSGKNCQDINECEEES 3726
Query: 819 EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD--VNECETG 865
C PG C NT GSY C P C Y C +C TG
Sbjct: 3727 IECGPGQMCFNTRGSYQCVDTP--CPATYRQGPSPGTCFRRCSQDCGTG 3773
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 946 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 3407 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 3465
Query: 1006 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 3466 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 3523
Query: 1066 TKCERT--------TCHDFLECQNSP 1083
CE CH C+N+P
Sbjct: 3524 AGCEDVDECLEGLDDCHYNQLCENTP 3549
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 751 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 807
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 4672
Query: 808 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 867
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 4673 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 4728
Query: 868 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 927
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 4729 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 4787
Query: 928 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 963
C G L DGK C + E Q + + A+I G SY
Sbjct: 4788 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 4846
Query: 964 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 4847 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 4901
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1076
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 4902 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 4960
Query: 1077 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1131
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 4961 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 5016
Query: 1132 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1172
R L A G VY +RA+ + L V R SV L
Sbjct: 5017 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 5057
Score = 187 bits (476), Expect = 4e-47
Identities = 123/358 (34%), Positives = 157/358 (43%), Gaps = 67/358 (18%)
Query: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
PC C G C+C G+A+ D +C D++EC D H C G+ CVN LGS+ C
Sbjct: 4644 PCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP 4703
Query: 748 ALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPE 805
C PG+ + DG CEDVDEC G C LC+NT G C C G+ +Q P
Sbjct: 4704 --DCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS----CPRGYRMQGPS 4757
Query: 806 GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETG 865
C+D+NEC L + C + C N GSY C +C G DG C T
Sbjct: 4758 LPCLDVNECLQLPKAC--AYQCHNLQGSYRC-----LCPPGQTLLRDGKAC-------TS 4803
Query: 866 VHRCGEG--QVCH------------NLPG-SY-----------------RCDCKAGFQRD 893
+ R G+ V H ++PG SY R C GF R
Sbjct: 4804 LERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQ 4863
Query: 894 AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC- 952
C D++EC LCQH C NT GSY+C C +G+ L GK C+D+NECE +
Sbjct: 4864 --NGVCTDLDECRVR--NLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIE 4919
Query: 953 ---SQECANIYGSYQCY---CRQGYQLAEDGHTC--TDIDECAQGAGILCTFRCLNVP 1002
Q C N GSYQC C Y+ TC +C G +R L +P
Sbjct: 4920 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQDCGTGGPSTLQYRLLPLP 4977
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 896
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 4613 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 4670
Query: 897 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 948
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 4671 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 4728
Query: 949 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1008
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 4729 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 4787
Query: 1009 CPEQGYTMTANGRSCKDVD 1027
CP G T+ +G++C ++
Sbjct: 4788 CP-PGQTLLRDGKACTSLE 4805
Score = 100 bits (250), Expect = 6e-21
Identities = 105/409 (25%), Positives = 143/409 (34%), Gaps = 98/409 (23%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 4566 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 4625
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT------------ 643
G D+DEC P C H C+N G + C C GF+L D R
Sbjct: 4626 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAH 4684
Query: 644 ----------------CRPEGHP----------PQPEAPQEPALKSEFSQVASNTI---- 673
C P+ P + E ++Q+ NT
Sbjct: 4685 LCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHR 4744
Query: 674 ------------PLPLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
LP N C C C + GS C C PG ++ DG +C +
Sbjct: 4745 CSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSL 4804
Query: 721 NECVTDLHTCSRGEHCVNTLG--------SFHCYKALT-------------CEPGYALKD 759
++ T S + L S+H + +L C PG+ ++
Sbjct: 4805 ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQN 4864
Query: 760 GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLS 818
G C D+DEC + + CQ C+NT+GS+ C C G+ P G NC DINEC S
Sbjct: 4865 GVCTDLDECRV-RNLCQHA--CRNTEGSYQCL----CPAGYRLLPSGKNCQDINECEEES 4917
Query: 819 EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD--VNECETG 865
C PG C NT GSY C P C Y C +C TG
Sbjct: 4918 IECGPGQMCFNTRGSYQCVDTP--CPATYRQGPSPGTCFRRCSQDCGTG 4964
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 946 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 4598 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 4656
Query: 1006 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 4657 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 4714
Query: 1066 TKCERT--------TCHDFLECQNSP 1083
CE CH C+N+P
Sbjct: 4715 AGCEDVDECLEGLDDCHYNQLCENTP 4740
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 202 bits (514), Expect = 2e-51
Identities = 148/461 (32%), Positives = 205/461 (44%), Gaps = 61/461 (13%)
Query: 751 CEPGYAL--KDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGN 807
C G+ L + C D DEC+ G C C N G F C C GF L + N
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA--CLNAPGRFSCT----CPTGFALAWDDRN 3390
Query: 808 CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVH 867
C D++EC + CR G C+N +GSY C + C G+ +D G C DV+EC G+
Sbjct: 3391 CRDVDECAWDAHLCREGQRCVNLLGSYRCLPD---CGPGFRVAD-GAGCEDVDECLEGLD 3446
Query: 868 RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCS 927
C Q+C N PG +RC C G++ C+DVNEC P + C + C N GSYRC
Sbjct: 3447 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLP-KACAYQCHNLQGSYRCL 3505
Query: 928 CASGFLLAADGKRCEDVNECEAQRCS------------QECANIYG-SY----------- 963
C G L DGK C + E Q + + A+I G SY
Sbjct: 3506 CPPGQTLLRDGKACTSL-ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPM 3564
Query: 964 ------QCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
+ +C G+ + ++G CTD+DEC LC C N GSYQC CP GY +
Sbjct: 3565 ALSSVGRAWCPPGF-IRQNG-VCTDLDECR--VRNLCQHACRNTEGSYQCLCP-AGYRLL 3619
Query: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ-VSKTKCERTTCHDF 1076
+G++C+D++EC + C + C N +GS++C+ CP Y Q S C R D
Sbjct: 3620 PSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQD- 3678
Query: 1077 LECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFT-----GDTIALNIIKGNEEGYFG 1131
C Y+L L V AH + AF+ + L++++ + F
Sbjct: 3679 --CGTGGPSTLQYRL-LPLPLGVRAH-HDVARLTAFSEVGVPANRTELSMLEPDPRSPFA 3734
Query: 1132 TRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFL 1172
R L A G VY +RA+ + L V R SV L
Sbjct: 3735 LRPLRAGLGAVYTRRALTRAGLYRLTVRAAAPRHQSVFVLL 3775
Score = 187 bits (476), Expect = 4e-47
Identities = 123/358 (34%), Positives = 157/358 (43%), Gaps = 67/358 (18%)
Query: 688 PCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYK 747
PC C G C+C G+A+ D +C D++EC D H C G+ CVN LGS+ C
Sbjct: 3362 PCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP 3421
Query: 748 ALTCEPGYALKDGE-CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPE 805
C PG+ + DG CEDVDEC G C LC+NT G C C G+ +Q P
Sbjct: 3422 --DCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHRCS----CPRGYRMQGPS 3475
Query: 806 GNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETG 865
C+D+NEC L + C + C N GSY C +C G DG C T
Sbjct: 3476 LPCLDVNECLQLPKAC--AYQCHNLQGSYRC-----LCPPGQTLLRDGKAC-------TS 3521
Query: 866 VHRCGEG--QVCH------------NLPG-SY-----------------RCDCKAGFQRD 893
+ R G+ V H ++PG SY R C GF R
Sbjct: 3522 LERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQ 3581
Query: 894 AFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC- 952
C D++EC LCQH C NT GSY+C C +G+ L GK C+D+NECE +
Sbjct: 3582 --NGVCTDLDECRVR--NLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIE 3637
Query: 953 ---SQECANIYGSYQCY---CRQGYQLAEDGHTC--TDIDECAQGAGILCTFRCLNVP 1002
Q C N GSYQC C Y+ TC +C G +R L +P
Sbjct: 3638 CGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCFRRCSQDCGTGGPSTLQYRLLPLP 3695
Score = 133 bits (334), Expect = 1e-30
Identities = 74/199 (37%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFG 896
+ N + C G+ G CVD +EC G C C N PG + C C GF
Sbjct: 3331 EENEVGCPEGFELDSQGAFCVDRDECSGGPSPC--SHACLNAPGRFSCTCPTGFALAWDD 3388
Query: 897 RGCIDVNECWASPGRLCQ--HTCENTLGSYRC--SCASGFLLAADGKRCEDVNEC----E 948
R C DV+EC A LC+ C N LGSYRC C GF + ADG CEDV+EC +
Sbjct: 3389 RNCRDVDEC-AWDAHLCREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDECLEGLD 3446
Query: 949 AQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCA 1008
+Q C N G ++C C +GY++ C D++EC Q C ++C N+ GSY+C
Sbjct: 3447 DCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQ-LPKACAYQCHNLQGSYRCL 3505
Query: 1009 CPEQGYTMTANGRSCKDVD 1027
CP G T+ +G++C ++
Sbjct: 3506 CP-PGQTLLRDGKACTSLE 3523
Score = 100 bits (250), Expect = 6e-21
Identities = 105/409 (25%), Positives = 143/409 (34%), Gaps = 98/409 (23%)
Query: 545 CNH-VMLSCCEGEEPLIVPEVRRPP-----EPAAAPRRVSEAEMAGREALSLGTEAELPN 598
CNH + + G +P +V +R +P A R A E +G
Sbjct: 3284 CNHSIQYNAARGPQPQLVQHLRASAISSAFDPEAEALRFQLATALQAEENEVGCPEGFEL 3343
Query: 599 SLPGD---DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRT------------ 643
G D+DEC P C H C+N G + C C GF+L D R
Sbjct: 3344 DSQGAFCVDRDECSGGPSP-CSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAH 3402
Query: 644 ----------------CRPEGHP----------PQPEAPQEPALKSEFSQVASNTI---- 673
C P+ P + E ++Q+ NT
Sbjct: 3403 LCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCENTPGGHR 3462
Query: 674 ------------PLPLPQPNTCKD-NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDI 720
LP N C C C + GS C C PG ++ DG +C +
Sbjct: 3463 CSCPRGYRMQGPSLPCLDVNECLQLPKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSL 3522
Query: 721 NECVTDLHTCSRGEHCVNTLG--------SFHCYKALT-------------CEPGYALKD 759
++ T S + L S+H + +L C PG+ ++
Sbjct: 3523 ERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQN 3582
Query: 760 GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLS 818
G C D+DEC + + CQ C+NT+GS+ C C G+ P G NC DINEC S
Sbjct: 3583 GVCTDLDECRV-RNLCQHA--CRNTEGSYQCL----CPAGYRLLPSGKNCQDINECEEES 3635
Query: 819 EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD--VNECETG 865
C PG C NT GSY C P C Y C +C TG
Sbjct: 3636 IECGPGQMCFNTRGSYQCVDTP--CPATYRQGPSPGTCFRRCSQDCGTG 3682
Score = 95.9 bits (237), Expect = 2e-19
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 11/146 (7%)
Query: 946 ECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
E EA R A + C +G++L G C D DEC+ G C+ CLN PG +
Sbjct: 3316 EAEALRFQLATALQAEENEVGCPEGFELDSQGAFCVDRDECSGGPSP-CSHACLNAPGRF 3374
Query: 1006 QCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK 1065
C CP G+ + + R+C+DVDECA H C E + C N+ GS+RCL +C P +
Sbjct: 3375 SCTCPT-GFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLP-DCGPGFRVADG 3432
Query: 1066 TKCERT--------TCHDFLECQNSP 1083
CE CH C+N+P
Sbjct: 3433 AGCEDVDECLEGLDDCHYNQLCENTP 3458
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 201 bits (510), Expect = 4e-51
Identities = 142/483 (29%), Positives = 203/483 (42%), Gaps = 74/483 (15%)
Query: 588 LSLGTEAELP--NSLPGD-DQDECLLLPGEL-CQHLCINTVGSYHCACFPGFSLQDDGRT 643
L+LGT L + LPG D DEC + +C NT SY C C PG+ + +G+
Sbjct: 14 LALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGY--KGEGKQ 71
Query: 644 CRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICS 703
C + + NG C C + G+ C+
Sbjct: 72 CE------------------------------DIDECENDYYNGGCVHECINIPGNYRCT 101
Query: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE-- 761
CF G+ + DG +C D++EC + C + CVN +GS+ C C G+ L D +
Sbjct: 102 CFDGFMLAHDGHNCLDVDECQDNNGGCQ--QICVNAMGSYEC----QCHSGFFLSDNQHT 155
Query: 762 ----CEDVDECAMGTHTCQPGFLCQNT-KGSFYCQARQRCMDGF-LQDPEGNCVDINECT 815
+ C H C +C+ T KG C C GF L + +C C
Sbjct: 156 CIHRSNEGMNCMNKDHGC--AHICRETPKGGVACD----CRPGFDLAQNQKDCT--LTCN 207
Query: 816 SLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVC 875
+ C+ SC +T TC C + Y DG C++ V+ G + C
Sbjct: 208 YGNGGCQ--HSCEDTDTGPTCG-----CHQKYALHSDGRTCIET----CAVNNGGCDRTC 256
Query: 876 HNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLA 935
+ RC C GF G+ C D+NEC + G C H C NT+GS+ C C G+ L
Sbjct: 257 KDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGG-CDHFCRNTVGSFECGCRKGYKLL 315
Query: 936 ADGKRCEDVNECEAQR-CSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC 994
D + C+D++EC +R C C N GS+QC C +GY L H C D+DEC+ G C
Sbjct: 316 TDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTH-CGDVDECSMSNG-SC 373
Query: 995 TFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF 1054
C+N GSY+C CP G + NG+ C + +C A+ + G
Sbjct: 374 DQGCVNTKGSYECVCP-PGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFL 432
Query: 1055 ECP 1057
CP
Sbjct: 433 SCP 435
Score = 183 bits (465), Expect = 7e-46
Identities = 114/356 (32%), Positives = 162/356 (45%), Gaps = 34/356 (9%)
Query: 719 DINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPG 778
D++EC C C NT S+ C C+PGY + +CED+DEC +
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCL----CKPGYKGEGKQCEDIDECENDYYNGGCV 88
Query: 779 FLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYTCQ 837
C N G++ C C DGF+ +G NC+D++EC + C+ C+N +GSY CQ
Sbjct: 89 HECINIPGNYRCT----CFDGFMLAHDGHNCLDVDECQDNNGGCQQ--ICVNAMGSYECQ 142
Query: 838 RNPLICARGYHASDDGTKCVDVNE----CETGVHRCGEGQVCHNLP-GSYRCDCKAGFQR 892
C G+ SD+ C+ + C H C +C P G CDC+ GF
Sbjct: 143 -----CHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--ICRETPKGGVACDCRPGFDL 195
Query: 893 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 952
+ C C G CQH+CE+T C C + L +DG+ C + C
Sbjct: 196 AQNQKDC--TLTCNYGNGG-CQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGC 252
Query: 953 SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1012
+ C + +C C G+ L DG TC DI+EC G C C N GS++C C +
Sbjct: 253 DRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNG-GCDHFCRNTVGSFECGC-RK 310
Query: 1013 GYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1068
GY + + R+C+D+DEC+ C C N GSF+CL C Y+ T C
Sbjct: 311 GYKLLTDERTCQDIDECSF-ERTCD--HICINSPGSFQCL---CHRGYILYGTTHC 360
Score = 149 bits (377), Expect = 1e-35
Identities = 98/317 (30%), Positives = 134/317 (42%), Gaps = 67/317 (21%)
Query: 809 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHR 868
VD++EC+ ++ C C NT SY C +C GY +G +C D++ECE +
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKC-----LCKPGY--KGEGKQCEDIDECENDYYN 84
Query: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSC 928
G C N+PG+YRC C GF G C+DV+EC + G CQ C N +GSY C C
Sbjct: 85 GGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGG-CQQICVNAMGSYECQC 143
Query: 929 ASGFLLAADGKRC-----EDVN--------------------ECEAQ------------- 950
SGF L+ + C E +N C+ +
Sbjct: 144 HSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCT 203
Query: 951 --------RCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVP 1002
C C + C C Q Y L DG TC I+ CA G C C +
Sbjct: 204 LTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNG-GCDRTCKDTA 260
Query: 1003 GSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQ 1062
+C+CP G+T+ +G++CKD++EC + C C N GSF C C Y
Sbjct: 261 TGVRCSCP-VGFTLQPDGKTCKDINECLVNNGGCD--HFCRNTVGSFEC---GCRKGY-- 312
Query: 1063 VSKTKCERTTCHDFLEC 1079
K + TC D EC
Sbjct: 313 --KLLTDERTCQDIDEC 327
Score = 134 bits (336), Expect = 7e-31
Identities = 111/355 (31%), Positives = 150/355 (42%), Gaps = 45/355 (12%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHP-----PQPEAPQE 658
D DEC G CQ +C+N +GSY C C GF L D+ TC + +
Sbjct: 117 DVDECQDNNGG-CQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH 175
Query: 659 PALKSEFSQVASNTIP-LPLPQPN-----TCK-DNGPCKQVCSTVGGSAICSCFPGYAIM 711
++ VA + P L Q TC NG C+ C C C YA+
Sbjct: 176 ICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALH 235
Query: 712 ADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALK-DGE-CEDVDECA 769
+DG +C I C + C R C +T C +C G+ L+ DG+ C+D++EC
Sbjct: 236 SDGRTC--IETCAVNNGGCDR--TCKDTATGVRC----SCPVGFTLQPDGKTCKDINECL 287
Query: 770 MGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPGFSCI 828
+ C C+NT GSF C C G+ L E C DI+EC S C CI
Sbjct: 288 VNNGGCD--HFCRNTVGSFEC----GCRKGYKLLTDERTCQDIDEC-SFERTC--DHICI 338
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKA 888
N+ GS+ C +C RGY T C DV+EC C +G C N GSY C C
Sbjct: 339 NSPGSFQC-----LCHRGYILYGT-THCGDVDECSMSNGSCDQG--CVNTKGSYECVCPP 390
Query: 889 GFQRDAFGRGCIDVNECW--ASPGRLCQHTCENTLGSYRC--SCASGFLLAADGK 939
G + G+ C++ +C A Q +C G C SC + L D +
Sbjct: 391 GRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSE 445
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 192 bits (489), Expect = 1e-48
Identities = 130/368 (35%), Positives = 172/368 (46%), Gaps = 43/368 (11%)
Query: 695 TVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFH-CYKALTCEP 753
T + C G+ D C EC L C G CV GS C+ C P
Sbjct: 101 TTEARTVLRCCRGWMQQPDEEGCLSA-ECSASL--CFHGGRCVP--GSAQPCH----CPP 151
Query: 754 GYALKDGECE-DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDI 811
G+ + C+ DVDEC CQ C NT GS+ C+ C GF L C+ I
Sbjct: 152 GF--QGPRCQYDVDECRTHNGGCQ--HRCVNTPGSYLCE----CKPGFRLHTDSRTCLAI 203
Query: 812 NECTSLSEPCRPGFSCIN-TVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCG 870
N C + C+ C+ T+ + CQ C G+ +DG CV + C C
Sbjct: 204 NSCALGNGGCQ--HHCVQLTITRHRCQ-----CRPGFQLQEDGRHCVRRSPCANRNGSCM 256
Query: 871 EGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCAS 930
C + G RC+C G+Q A G+ C DV+EC A + C H C NT GS++C C +
Sbjct: 257 HR--CQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQ-CAHGCLNTQGSFKCVCHA 313
Query: 931 GFLLAADGKRC-----EDVNECEAQR--CSQECANIYGSYQCYCRQGYQLAEDGHTCTDI 983
G+ L ADG++C E VN CEA CS C++ C C +GY+L D TC D+
Sbjct: 314 GYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDV 373
Query: 984 DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCH 1043
D+CA C C N PG Y+C C GY ++A+G C+DVDECA C C
Sbjct: 374 DDCADSP--CCQQVCTNNPGGYECGC-YAGYRLSADGCGCEDVDECASSRGGCE--HHCT 428
Query: 1044 NIQGSFRC 1051
N+ GSF+C
Sbjct: 429 NLAGSFQC 436
Score = 191 bits (484), Expect = 5e-48
Identities = 122/342 (35%), Positives = 168/342 (49%), Gaps = 37/342 (10%)
Query: 697 GGSAICSCFPGYAIMADGVSCE-DINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGY 755
G + C C PG+ G C+ D++EC T C CVNT GS+ C C+PG+
Sbjct: 142 GSAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH--RCVNTPGSYLC----ECKPGF 191
Query: 756 ALKDGE--CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDIN 812
L C ++ CA+G CQ + Q T CQ C GF LQ+ +CV +
Sbjct: 192 RLHTDSRTCLAINSCALGNGGCQHHCV-QLTITRHRCQ----CRPGFQLQEDGRHCVRRS 246
Query: 813 ECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEG 872
C + + C C G C+ C GY + DG C DV+EC G+ +C G
Sbjct: 247 PCANRNGSCM--HRCQVVRGLARCE-----CHVGYQLAADGKACEDVDECAAGLAQCAHG 299
Query: 873 QVCHNLPGSYRCDCKAGFQRDAFGRGCID-----VNECWASPGRLCQHTCENTLGSYRCS 927
C N GS++C C AG++ A GR C VN C A+ G C H C +T C+
Sbjct: 300 --CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGG-CSHGCSHTSAGPLCT 356
Query: 928 CASGFLLAADGKRCEDVNEC-EAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC 986
C G+ L D + C DV++C ++ C Q C N G Y+C C GY+L+ DG C D+DEC
Sbjct: 357 CPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC 416
Query: 987 AQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDE 1028
A G C C N+ GS+QC+C E GY + + R C ++E
Sbjct: 417 ASSRG-GCEHHCTNLAGSFQCSC-EAGYRLHEDRRGCSPLEE 456
Score = 182 bits (463), Expect = 1e-45
Identities = 108/311 (34%), Positives = 145/311 (46%), Gaps = 34/311 (10%)
Query: 686 NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVN-TLGSFH 744
NG C+ C GS +C C PG+ + D +C IN C C HCV T+
Sbjct: 169 NGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH--HCVQLTITRHR 226
Query: 745 CYKALTCEPGYALKDG--ECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQ 802
C C PG+ L++ C CA +C CQ +G C+ C G+
Sbjct: 227 CQ----CRPGFQLQEDGRHCVRRSPCANRNGSCM--HRCQVVRGLARCE----CHVGYQL 276
Query: 803 DPEGN-CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVD--- 858
+G C D++EC + C G C+NT GS+ C +C GY DG +C
Sbjct: 277 AADGKACEDVDECAAGLAQCAHG--CLNTQGSFKC-----VCHAGYELGADGRQCYRIEM 329
Query: 859 --VNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT 916
VN CE C G C + C C G++ D R CIDV++C SP CQ
Sbjct: 330 EIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP--CCQQV 385
Query: 917 CENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQGYQLA 974
C N G Y C C +G+ L+ADG CEDV+EC + R C C N+ GS+QC C GY+L
Sbjct: 386 CTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLH 445
Query: 975 EDGHTCTDIDE 985
ED C+ ++E
Sbjct: 446 EDRRGCSPLEE 456
Score = 162 bits (410), Expect = 2e-39
Identities = 149/491 (30%), Positives = 196/491 (39%), Gaps = 81/491 (16%)
Query: 604 DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRP-----------EGHPPQ 652
D DEC G CQH C+NT GSY C C PGF L D RTC + H Q
Sbjct: 161 DVDECRTHNGG-CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQ 219
Query: 653 PEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMA 712
+ Q+ + P NG C C V G A C C GY + A
Sbjct: 220 LTITRHRCQCRPGFQLQEDGRHCVRRSP-CANRNGSCMHRCQVVRGLARCECHVGYQLAA 278
Query: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL-KDG------ECEDV 765
DG +CED++EC L C+ G C+NT GSF C C GY L DG E E V
Sbjct: 279 DGKACEDVDECAAGLAQCAHG--CLNTQGSFKC----VCHAGYELGADGRQCYRIEMEIV 332
Query: 766 DECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPCRPG 824
+ C C G C +T C C G+ L + C+D+++C PC
Sbjct: 333 NSCEANNGGCSHG--CSHTSAGPLC----TCPRGYELDTDQRTCIDVDDCA--DSPCCQQ 384
Query: 825 FSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC 884
C N G Y C C GY S DG C DV+EC + R G C NL GS++C
Sbjct: 385 V-CTNNPGGYECG-----CYAGYRLSADGCGCEDVDECASS--RGGCEHHCTNLAGSFQC 436
Query: 885 DCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDV 944
C+AG++ RGC + E + L R L + +D
Sbjct: 437 SCEAGYRLHEDRRGCSPLEEPMVD--------LDGELPFVRPLPHIAVLQDELPQLFQD- 487
Query: 945 NECEAQRCSQECANIYGSYQCYCRQGYQLAED--GHTCT-DIDECAQGAGILCTFRCLNV 1001
+ +E A + G + + + +D GH C+ D+C G L L +
Sbjct: 488 ---DDVGADEEEAELRGEHT--LTEKFVCLDDSFGHDCSLTCDDCRNGGTCL-----LGL 537
Query: 1002 PGSYQCACPEQGYTMTANGRSCKD---VDECALGTHNCSEAETCHNIQGSFRCLRFECPP 1058
G C CPE G+T +C C+ +C TC ++ G+ R CPP
Sbjct: 538 DG---CDCPE-GWTGLICNETCPPDTFGKNCSFSC-SCQNGGTCDSVTGACR-----CPP 587
Query: 1059 NYVQVSKTKCE 1069
VS T CE
Sbjct: 588 G---VSGTNCE 595
Score = 156 bits (394), Expect = 1e-37
Identities = 105/299 (35%), Positives = 137/299 (45%), Gaps = 37/299 (12%)
Query: 795 RCMDGFLQDP-EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDG 853
RC G++Q P E C+ SL C G C+ GS P C G+ G
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASL---CFHGGRCVP--GS----AQPCHCPPGFQ----G 155
Query: 854 TKC-VDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
+C DV+EC T H G C N PGSY C+CK GF+ R C+ +N C G
Sbjct: 156 PRCQYDVDECRT--HNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG- 212
Query: 913 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQECANIYGSYQCYCRQ 969
CQH C + T+ +RC C GF L DG+ C + C + C C + G +C C
Sbjct: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHV 272
Query: 970 GYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC-----K 1024
GYQLA DG C D+DECA G C CLN GS++C C GY + A+GR C +
Sbjct: 273 GYQLAADGKACEDVDECAAGLA-QCAHGCLNTQGSFKCVC-HAGYELGADGRQCYRIEME 330
Query: 1025 DVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSP 1083
V+ C CS C + C CP Y + ++ TC D +C +SP
Sbjct: 331 IVNSCEANNGGCSHG--CSHTSAGPLC---TCPRGY----ELDTDQRTCIDVDDCADSP 380
Score = 91.3 bits (225), Expect = 5e-18
Identities = 155/674 (22%), Positives = 219/674 (32%), Gaps = 175/674 (25%)
Query: 446 CAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCC--VSYLQEKSCMAGVLGAKEGETCG 503
C G Q D C+ + C H C V L C G A +G+ C
Sbjct: 229 CRPGFQLQEDGRHCVRRSPCANRNGSCM----HRCQVVRGLARCECHVGYQLAADGKAC- 283
Query: 504 AEDNDSCGISLYKQCCDC----------CGLGLRVRAEGQSC------------ESNPNL 541
ED D C L + C C G + A+G+ C +N
Sbjct: 284 -EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
Query: 542 GYPCNHV----MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
+ C+H + +C G E + A + G A
Sbjct: 343 SHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYR 402
Query: 598 NSLPG---DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPE 654
S G +D DEC G C+H C N GS+ C+C G+ L +D R C P P
Sbjct: 403 LSADGCGCEDVDECASSRGG-CEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDL 461
Query: 655 APQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADG 714
+ P ++ PLP +D P D
Sbjct: 462 DGELPFVR-------------PLPHIAVLQDELP-------------------QLFQDDD 489
Query: 715 VSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHT 774
V ++ + HT + C++ C +LTC+ +C + C +G
Sbjct: 490 VGADEEEAELRGEHTLTEKFVCLDDSFGHDC--SLTCD--------DCRNGGTCLLGLDG 539
Query: 775 CQ-----PGFLCQNT--KGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSC 827
C G +C T +F C +C + C S++ CR C
Sbjct: 540 CDCPEGWTGLICNETCPPDTFGKNCSFSC----------SCQNGGTCDSVTGACR----C 585
Query: 828 INTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCD-- 885
V C+ C +GY+ KC C CH L G+ CD
Sbjct: 586 PPGVSGTNCEDG---CPKGYYGKHCRKKC-----------NCANRGRCHRLYGACLCDPG 631
Query: 886 -----CKAGFQRDAFGRGCIDVNECWASPGRLCQHT--CENTLGSYRCSCASGFLLAADG 938
C AFG GC + +C + HT C+ GS CSC +GF G
Sbjct: 632 LYGRFCHLTCPPWAFGPGCSEECQC------VQPHTQSCDKRDGS--CSCKAGF----RG 679
Query: 939 KRCEDVNECEA--------QRCS----QECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC 986
+RC+ ECE Q C+ C ++ G C G+Q G C EC
Sbjct: 680 ERCQ--AECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQ----GEDCG--QEC 731
Query: 987 AQGA-GILCTFRCL-------NVPGSYQCACPEQGYTMTANGRSCKDVD-ECALGTHNCS 1037
G G+ C+ C V G QC CP GR+ +D + +C G
Sbjct: 732 PVGTFGVNCSSSCSCGGAPCHGVTG--QCRCPP--------GRTGEDCEADCPEGRWGLG 781
Query: 1038 EAETCHNIQGSFRC 1051
E C Q + RC
Sbjct: 782 CQEICPACQHAARC 795
Score = 68.2 bits (165), Expect = 5e-11
Identities = 185/848 (21%), Positives = 259/848 (30%), Gaps = 252/848 (29%)
Query: 450 QQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDS 509
Q+ ID D+C + P C+ + Y E C AG + +G CG ED D
Sbjct: 367 QRTCIDVDDCADSP-------CCQQVCTNNPGGY--ECGCYAGYRLSADG--CGCEDVDE 415
Query: 510 CGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLI-----VPEV 564
C S C L + SCE+ GY + C EEP++ +P V
Sbjct: 416 CASSRGGCEHHCTNLAGSFQC---SCEA----GYRLHEDRRGCSPLEEPMVDLDGELPFV 468
Query: 565 RRPPEPAAA----PRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECL--------LLP 612
R P A P+ + ++ E EAEL ++ CL L
Sbjct: 469 RPLPHIAVLQDELPQLFQDDDVGADEE-----EAELRGEHTLTEKFVCLDDSFGHDCSLT 523
Query: 613 GELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNT 672
+ C++ +G C C G++ TC P+ V
Sbjct: 524 CDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
Query: 673 IPLPLPQPNTCKDNGP-------CKQVCSTVGGS------AICSCFPGY---------AI 710
P C+D P C++ C+ C C PG
Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 711 MADGVSCEDINECVTDLHT---------CS-----RGEHCVNT--LGSFH--CYKALTCE 752
A G C + +CV HT CS RGE C LG F C++A TC
Sbjct: 644 WAFGPGCSEECQCVQP-HTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP 702
Query: 753 PGYALKD--GEC----------EDV-DECAMGTH------TCQPGFL-CQNTKGSFYCQA 792
G A GEC ED EC +GT +C G C G C
Sbjct: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPP 762
Query: 793 RQRCMDGFLQDPEGN----CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYH 848
+ D PEG C +I + C P + + R +C G++
Sbjct: 763 GRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWY 822
Query: 849 ASDDGTKCVDVNE------------------------CETGVHRCGEGQVCHNLPGSYRC 884
T+C N+ C+TG C+ G C
Sbjct: 823 GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC 882
Query: 885 D-------CKAGF---------QRDAFGRGCIDVNECWASP----------------GRL 912
D C+AG+ + FG GC +C G
Sbjct: 883 DAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTF 942
Query: 913 CQHTCE------------NTLGSYRCSCASGFLLAADGKRCEDVNE-CEAQ----RCSQE 955
C+H C N C +G L G+R E C A CSQ
Sbjct: 943 CEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQA 1002
Query: 956 CANIYGSY------QCYCRQGYQ---------------------LAEDGHTCTDID---E 985
CA G+ QC+C G+ L ++G TC +
Sbjct: 1003 CACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCA 1062
Query: 986 CAQG-AGILCTFRCLNV-------------------PGSYQCACPEQGYTMTANGRSCKD 1025
C +G AG+ C CL P + +C CP G+T G C+
Sbjct: 1063 CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPA-GWT----GDKCQS 1117
Query: 1026 ------VDECALGTHNCSEAETCHNIQGSFRC--------LRFECPP-----NYVQVSKT 1066
E +C CH++ G+ RC CPP + Q+ +
Sbjct: 1118 PCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQC 1177
Query: 1067 KCERTTCH 1074
E CH
Sbjct: 1178 PGENPACH 1185
Score = 58.5 bits (140), Expect = 4e-08
Identities = 106/459 (23%), Positives = 143/459 (31%), Gaps = 117/459 (25%)
Query: 611 LPGELCQHLCINTVG------SYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSE 664
L G+ C+H C+ G S HCAC G++ G C E P A
Sbjct: 1037 LYGDNCRHSCLCQNGGTCDPVSGHCACPEGWA----GLACEKECLPRDVRAG-------- 1084
Query: 665 FSQVASNTIPLPLPQPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCED--- 719
C+ +G C +C G C C G+ G C+
Sbjct: 1085 ------------------CRHSGGCLNGGLCDPHTGR--CLCPAGWT----GDKCQSPCL 1120
Query: 720 ---INECVTDLHTCSRGEHCVNTLGSFHCYKALT-------CEPGYALKDGECEDVDECA 769
E +C G C + G+ C T C PG +D C + +C
Sbjct: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGED--CAQMCQCP 1178
Query: 770 MGTHTCQPGF-LCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCI 828
C P C G +QRC G C + C + G SC
Sbjct: 1179 GENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP---GCEQLCGCLN-------GGSCD 1228
Query: 829 NTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHR--CGEGQVCHNLPGSYRCD- 885
G+ C+ C G+ +D C H CG+G C + G+ C
Sbjct: 1229 AATGA--CR-----CPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPP 1281
Query: 886 ------CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGK 939
C+ G ++ FG GC + C G LC H + CSC G+ G+
Sbjct: 1282 GRAGVRCERGCPQNRFGVGC--EHTCSCRNGGLC-HASNGS-----CSCGLGW----TGR 1329
Query: 940 RCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG-AGILCTFRC 998
CE C R C +C C TC C G G C C
Sbjct: 1330 HCE--LACPPGRYGAAC-----HLECSCHNNSTCEPATGTC----RCGPGFYGQACEHPC 1378
Query: 999 LNVPGSYQCACPEQGYTMTANGRSCKDVDE---CALGTH 1034
PG + C QG +G C + C G H
Sbjct: 1379 --PPGFHGAGC--QGLCWCQHGAPCDPISGRCLCPAGFH 1413
Score = 53.5 bits (127), Expect = 1e-06
Identities = 104/432 (24%), Positives = 133/432 (30%), Gaps = 115/432 (26%)
Query: 608 CLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQ 667
C PG C H+ + C C PGF+ + C P F +
Sbjct: 1132 CSCPPGAACHHV------TGACRCPPGFTGSGCEQACPP----------------GSFGE 1169
Query: 668 VASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDL 727
+ P P G C G S C PG G CE + C+
Sbjct: 1170 DCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRY----GPGCEQLCGCLN-- 1223
Query: 728 HTCSRGEHCVNTLGSFHCYKA-------LTCEPGYALKDGECEDVDECAMGTHTCQPGFL 780
G C G+ C LTC G C V C G
Sbjct: 1224 -----GGSCDAATGACRCPTGFLGTDCNLTCPQGRF--GPNCTHVCGCGQGA-------A 1269
Query: 781 CQNTKGSFYC---QARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTC- 836
C G+ C +A RC G Q+ G + + C+ CR G C + GS +C
Sbjct: 1270 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS-----CRNGGLCHASNGSCSCG 1323
Query: 837 -----QRNPLICARGYHASDDGTKCVDVNE--CE--TGVHRCGEG---QVCHNL------ 878
+ L C G + + +C N CE TG RCG G Q C +
Sbjct: 1324 LGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFH 1383
Query: 879 -----------------PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTL 921
P S RC C AGF RGC S G C C+
Sbjct: 1384 GAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEP-----GSFGEGCHQRCDCD- 1437
Query: 922 GSYRCSCASGFLLAADGKRCEDVN-ECE----AQRCSQECANIYG------SYQCYCRQG 970
G C +G L G+ N +C C+ C G S QC+C G
Sbjct: 1438 GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1497
Query: 971 YQLAEDGHTCTD 982
Y G TC +
Sbjct: 1498 YM----GPTCRE 1505
Score = 33.1 bits (74), Expect = 1.6
Identities = 56/216 (25%), Positives = 70/216 (32%), Gaps = 56/216 (25%)
Query: 20 LGPSVAAAAP--------RQDC---TGVECPPLEN--CIEEALEPGACCATC----VQQG 62
+GPS A P R C G C P+ E AC C V+ G
Sbjct: 1025 MGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAG 1084
Query: 63 CACEGYQYYDCLQGGFV-----RGRVPAG-----------QSYFVDFGSTECSCPPGGGK 106
C G CL GG R PAG + +F + + CSCPPG
Sbjct: 1085 CRHSG----GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGA-- 1138
Query: 107 ISCQFML----CPE--LPPNCIEAVVVADSCPQCGQV--------GCVHAGHKYAAGHTV 152
+C + CP C +A C Q+ C A +
Sbjct: 1139 -ACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGY 1197
Query: 153 HLPPCRACHCPDAGGELICYQLPGC-HGNFSDAEEG 187
H P C+ CP C QL GC +G DA G
Sbjct: 1198 HGPSCQQ-RCPPGRYGPGCEQLCGCLNGGSCDAATG 1232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,233,174
Number of Sequences: 37866
Number of extensions: 3586449
Number of successful extensions: 33601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 688
Number of HSP's that attempted gapping in prelim test: 20288
Number of HSP's gapped (non-prelim): 6081
length of query: 1184
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1071
effective length of database: 13,968,660
effective search space: 14960434860
effective search space used: 14960434860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.