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Search of human proteins with 13376367
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376367 WD repeat domain 76 [Homo sapiens]
(626 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13376367 WD repeat domain 76 [Homo sapiens] 1258 0.0
gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens] 55 1e-07
gi|14149987 WD repeat domain 24 [Homo sapiens] 47 7e-05
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 44 4e-04
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 44 6e-04
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 44 6e-04
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 42 0.001
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 41 0.004
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 40 0.005
gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens] 39 0.011
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 39 0.014
gi|209529711 coronin, actin binding protein, 2A [Homo sapiens] 39 0.019
gi|16554585 coronin, actin binding protein, 2A [Homo sapiens] 39 0.019
gi|110349719 titin isoform N2-A [Homo sapiens] 38 0.025
gi|110349717 titin isoform novex-2 [Homo sapiens] 38 0.025
gi|110349713 titin isoform novex-1 [Homo sapiens] 38 0.025
gi|110349715 titin isoform N2-B [Homo sapiens] 38 0.025
gi|127138957 zinc finger protein 537 [Homo sapiens] 37 0.042
gi|168229161 coronin 7 [Homo sapiens] 37 0.042
gi|38605733 nucleoporin 43kDa [Homo sapiens] 36 0.093
gi|112421108 capicua homolog [Homo sapiens] 36 0.093
gi|4758220 XAP-5 protein [Homo sapiens] 35 0.16
gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Hom... 35 0.21
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 35 0.21
gi|4557757 MutL protein homolog 1 [Homo sapiens] 35 0.27
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 35 0.27
gi|219802034 nuclear factor related to kappaB binding protein is... 35 0.27
gi|23346420 nuclear factor related to kappaB binding protein iso... 35 0.27
gi|21264602 laminin alpha 5 [Homo sapiens] 35 0.27
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 34 0.35
>gi|13376367 WD repeat domain 76 [Homo sapiens]
Length = 626
Score = 1258 bits (3256), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 1 MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQ 60
MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQ
Sbjct: 1 MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQ 60
Query: 61 LDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTES 120
LDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTES
Sbjct: 61 LDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTES 120
Query: 121 NKLQPKRTADAMNLSVDVESSQDGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASL 180
NKLQPKRTADAMNLSVDVESSQDGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASL
Sbjct: 121 NKLQPKRTADAMNLSVDVESSQDGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASL 180
Query: 181 QLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLV 240
QLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLV
Sbjct: 181 QLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLV 240
Query: 241 ADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNG 300
ADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNG
Sbjct: 241 ADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNG 300
Query: 301 MVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHS 360
MVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHS
Sbjct: 301 MVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHS 360
Query: 361 QPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLI 420
QPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLI
Sbjct: 361 QPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLI 420
Query: 421 VGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRL 480
VGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRL
Sbjct: 421 VGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRL 480
Query: 481 NSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRH 540
NSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRH
Sbjct: 481 NSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRH 540
Query: 541 NTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINA 600
NTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINA
Sbjct: 541 NTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINA 600
Query: 601 MHPTRYILAGGNSSGKIHVFMNEKSC 626
MHPTRYILAGGNSSGKIHVFMNEKSC
Sbjct: 601 MHPTRYILAGGNSSGKIHVFMNEKSC 626
>gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens]
Length = 427
Score = 55.5 bits (132), Expect = 1e-07
Identities = 75/308 (24%), Positives = 133/308 (43%), Gaps = 31/308 (10%)
Query: 318 SMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHIL 377
S+A HP+ T VAVG+K G + L + + K + ++ L F+P N
Sbjct: 116 SLAWHPTHPST-VAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGS-ITGLKFNPLNTNQFY 173
Query: 378 SLSYDGTLRCGDFSRAIFEEVYRNERSS--FSSFDFLAEDASTLIVGHWDGNMSLVDRRT 435
+ S +GT R DF I ++ + F S D ++ + ++ G GN+ L++
Sbjct: 174 ASSMEGTTRLQDFKGNILRVFASSDTINIWFCSLD-VSASSRMVVTGDNVGNVILLN--- 229
Query: 436 PGTSYEKLTSSSMGKIRTVHV--HPVHRQYFITAGLRDT-HIYDARRLNSRRSQPLISLT 492
++L + M K + HV +P + TA + T I+D R++ + S +
Sbjct: 230 --MDGKELWNLRMHKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKAS--FLYSL 285
Query: 493 EHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRHNTFTGRWLTRFQ 552
H + +A FSP G R++TT +R++ +S + L I H + LT +
Sbjct: 286 PHRHPVNAACFSP-DGARLLTTDQKSEIRVYSASQWDCPLGL---IPHPHRHFQHLTPIK 341
Query: 553 AMWDPKQEDCVIVGSMAHP----------RRVEIFH-ETGKRVHSFGGEYLVSVCSINAM 601
A W P+ + ++VG P R +++F +GK + + S+N
Sbjct: 342 AAWHPRY-NLIVVGRYPDPNFKSCTPYELRTIDVFDGNSGKMMCQLYDPESSGISSLNEF 400
Query: 602 HPTRYILA 609
+P LA
Sbjct: 401 NPMGDTLA 408
>gi|14149987 WD repeat domain 24 [Homo sapiens]
Length = 790
Score = 46.6 bits (109), Expect = 7e-05
Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 1/140 (0%)
Query: 329 LVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCG 388
L+A A G V +L + + +F H + V+ + F P +LS S DG ++C
Sbjct: 89 LLATAATNGVVVTWNLGRPSRNKQDQLFTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCF 148
Query: 389 DFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSM 448
D R + + S F D T +GN+ L D R P E++ ++
Sbjct: 149 DLRRKDSVSTFSGQSESVRDVQFSIRDYFTFASTFENGNVQLWDIRRPDRC-ERMFTAHN 207
Query: 449 GKIRTVHVHPVHRQYFITAG 468
G + HP R + T G
Sbjct: 208 GPVFCCDWHPEDRGWLATGG 227
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 43.9 bits (102), Expect = 4e-04
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 8/150 (5%)
Query: 376 ILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRT 435
+ S S D T+ D S + F +A TLI G +D +++L D R+
Sbjct: 272 LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRS 331
Query: 436 PGTSYEKLT-SSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRLNSRRSQPLISLTEH 494
P S+ S + ++ H P H A D +Y+ L++R +P+ +L H
Sbjct: 332 PDESHRMWRFSGQIERVTWNHFSPCH----FLASTDDGFVYN---LDARSDKPIFTLNAH 384
Query: 495 TKSIASAYFSPLTGNRVVTTCADCNLRIFD 524
I+ S +VT AD ++I+D
Sbjct: 385 NDEISGLDLSSQIKGCLVTASADKYVKIWD 414
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/184 (23%), Positives = 77/184 (41%), Gaps = 21/184 (11%)
Query: 350 EDGVYVFHPHSQ-----PVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERS 404
+D V + +P ++ +SC+ +S + + S Y+GT+ D +VY+
Sbjct: 455 QDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEK 514
Query: 405 SFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGK--IRTVHVHPVHRQ 462
S DF D L G D + L T+ + +S K + V P R
Sbjct: 515 RCWSVDFNLMDPKLLASGSDDAKVKLW-----STNLDNSVASIEAKANVCCVKFSPSSR- 568
Query: 463 YFITAGLRD--THIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNL 520
Y + G D H YD R QP++ H K+++ A F ++G +V+ D L
Sbjct: 569 YHLAFGCADHCVHYYDLR----NTKQPIMVFKGHRKAVSYAKF--VSGEEIVSASTDSQL 622
Query: 521 RIFD 524
++++
Sbjct: 623 KLWN 626
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/184 (23%), Positives = 77/184 (41%), Gaps = 21/184 (11%)
Query: 350 EDGVYVFHPHSQ-----PVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERS 404
+D V + +P ++ +SC+ +S + + S Y+GT+ D +VY+
Sbjct: 431 QDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEK 490
Query: 405 SFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGK--IRTVHVHPVHRQ 462
S DF D L G D + L T+ + +S K + V P R
Sbjct: 491 RCWSVDFNLMDPKLLASGSDDAKVKLW-----STNLDNSVASIEAKANVCCVKFSPSSR- 544
Query: 463 YFITAGLRD--THIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNL 520
Y + G D H YD R QP++ H K+++ A F ++G +V+ D L
Sbjct: 545 YHLAFGCADHCVHYYDLR----NTKQPIMVFKGHRKAVSYAKF--VSGEEIVSASTDSQL 598
Query: 521 RIFD 524
++++
Sbjct: 599 KLWN 602
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 15/126 (11%)
Query: 143 DGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPP--- 199
D DS D T AL+ G+ ++ L + D L L E+A +L + + P
Sbjct: 290 DQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGG 349
Query: 200 KSKRKKPKRENGIGCRRSM-------RLLKVDPSGVSLPAAPTPPTLVA-----DETPLL 247
+ +R+KP E G RRS+ R + P+G + P PT T A +P+
Sbjct: 350 RRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVG 409
Query: 248 PPGPLE 253
PP L+
Sbjct: 410 PPSGLQ 415
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/223 (22%), Positives = 84/223 (37%), Gaps = 9/223 (4%)
Query: 308 VYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLY 367
VYK ++S+ + LV G+ V L D T + F H +
Sbjct: 106 VYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKS---LCTFRGHESIIYSTI 162
Query: 368 FSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGN 427
+SP P S S D TLR D A V ++ S D+ + + L+ G D +
Sbjct: 163 WSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCS 222
Query: 428 MSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRLNSRRSQP 487
+ D R +L + IR V P H + ++ + R N +
Sbjct: 223 LRGWDLRNVRQPVFELLGHTYA-IRRVKFSPFHASVLASC----SYDFTVRFWNFSKPDS 277
Query: 488 LISLTE-HTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCIS 529
L+ E HT+ FS + +V D ++I+D +C++
Sbjct: 278 LLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLT 320
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.005
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 111 NSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSD----EDTTPALDFSGLSPYERKR 166
+SSS ES P++ + +SS++ + + ED + +P E+KR
Sbjct: 278 SSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKR 337
Query: 167 LKNISENADFFASLQLSESAARLREMIEKRQPPKSKRK 204
K+ SE +D + A+ M +K+ PPK +RK
Sbjct: 338 RKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERK 375
>gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]
Length = 601
Score = 39.3 bits (90), Expect = 0.011
Identities = 59/245 (24%), Positives = 93/245 (37%), Gaps = 53/245 (21%)
Query: 93 IIPPKMKNTSSKAESTLQN-SSSAVHTESNKLQPKRTADAMNLSVDVES-------SQDG 144
I+ PK K +SS E + Q S A +S+K + A+ L +++S
Sbjct: 195 ILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKS 254
Query: 145 DSDEDTTPA------------------LDFSGLSPYERKRLKNISENADFFASLQLSESA 186
SD ++P LD SGL P + ++ L+ E
Sbjct: 255 SSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPIL------VESDSSSGGELEAGELV 308
Query: 187 A--RLREMIEKRQPPKSKRKKPKREN----GIGCRRSMRLLKVDPSGVSLPAAPTP--PT 238
RE+ +K++ KSK+KK K ++ +RS+ L V V++ + P P P
Sbjct: 309 IDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPY 368
Query: 239 LVADETPLLPP-----GPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKS 293
A PL P G E + +E + ER +G KP KN K
Sbjct: 369 AGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERG--------EKPKKKNMSAYQVFCKE 420
Query: 294 YKANL 298
Y+ +
Sbjct: 421 YRVTI 425
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 38.9 bits (89), Expect = 0.014
Identities = 51/215 (23%), Positives = 88/215 (40%), Gaps = 31/215 (14%)
Query: 68 KSLSEKNSNNEVAC-KKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPK 126
+S S+++S+ E A KK K K R P +S++ S SSS H ES K + +
Sbjct: 1052 RSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKR 1111
Query: 127 RTADAMNLSVDVESSQDGDSDEDTTPALDFSGLSPYERKRLKNISENADFFA-----SLQ 181
R+A S+ + T +L+ ++R+R + + A +
Sbjct: 1112 RSA-----------SRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKR 1160
Query: 182 LSESAARLREMIEKRQP------PKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLP---- 231
S S + E R+P P+++ P+R+ + L + +P LP
Sbjct: 1161 RSRSPSSEHRAREHRRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPTRLP 1220
Query: 232 ----AAPTPPTLVADETPLLPPGPLEMTSENQEDN 262
A +P AD+ PL P LE+ +E + D+
Sbjct: 1221 ALGEAHVSPEVATADKAPLQAPPVLEVAAECEPDD 1255
>gi|209529711 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 38.5 bits (88), Expect = 0.019
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 21/159 (13%)
Query: 413 AEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLR-D 471
+EDA+ I W L+ R T+Y K ++ V HP +AG
Sbjct: 102 SEDATIKI---WSIPKQLLTRNL--TAYRKELVGHARRVGLVEWHPTAANILFSAGYDYK 156
Query: 472 THIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSC---- 527
I++ S + P+ +++ H I S F+ G+ + TTC D +R+ D
Sbjct: 157 VMIWNLDTKESVITSPMSTISCHQDVILSMSFNT-NGSLLATTCKDRKIRVIDPRAGTVL 215
Query: 528 --------ISSKIPLLTTIRH--NTFTGRWLTRFQAMWD 556
+SK+ L ++ +T T RW R A+WD
Sbjct: 216 QEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWD 254
>gi|16554585 coronin, actin binding protein, 2A [Homo sapiens]
Length = 525
Score = 38.5 bits (88), Expect = 0.019
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 21/159 (13%)
Query: 413 AEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLR-D 471
+EDA+ I W L+ R T+Y K ++ V HP +AG
Sbjct: 102 SEDATIKI---WSIPKQLLTRNL--TAYRKELVGHARRVGLVEWHPTAANILFSAGYDYK 156
Query: 472 THIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSC---- 527
I++ S + P+ +++ H I S F+ G+ + TTC D +R+ D
Sbjct: 157 VMIWNLDTKESVITSPMSTISCHQDVILSMSFNT-NGSLLATTCKDRKIRVIDPRAGTVL 215
Query: 528 --------ISSKIPLLTTIRH--NTFTGRWLTRFQAMWD 556
+SK+ L ++ +T T RW R A+WD
Sbjct: 216 QEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWD 254
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 38.1 bits (87), Expect = 0.025
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 21/112 (18%)
Query: 213 GCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMT-----------SENQED 261
GC R+L + G+ LPA T P V++ P LPPG + + + + D
Sbjct: 25265 GCSYYFRVLASNEYGIGLPAETTEPVKVSE--PPLPPGRVTLVDVTRNTATIKWEKPESD 25322
Query: 262 NNERFKGFLHTWAGMSKPSSKNTEK--GLSSIKSYKANLNGMVISEDTVYKV 311
+ G+ + + +K +EK + +K+ +A ++G+ E+ V++V
Sbjct: 25323 GGSKITGY------VVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRV 25368
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 38.1 bits (87), Expect = 0.025
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 21/112 (18%)
Query: 213 GCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMT-----------SENQED 261
GC R+L + G+ LPA T P V++ P LPPG + + + + D
Sbjct: 18960 GCSYYFRVLASNEYGIGLPAETTEPVKVSE--PPLPPGRVTLVDVTRNTATIKWEKPESD 19017
Query: 262 NNERFKGFLHTWAGMSKPSSKNTEK--GLSSIKSYKANLNGMVISEDTVYKV 311
+ G+ + + +K +EK + +K+ +A ++G+ E+ V++V
Sbjct: 19018 GGSKITGY------VVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRV 19063
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 38.1 bits (87), Expect = 0.025
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 21/112 (18%)
Query: 213 GCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMT-----------SENQED 261
GC R+L + G+ LPA T P V++ P LPPG + + + + D
Sbjct: 18893 GCSYYFRVLASNEYGIGLPAETTEPVKVSE--PPLPPGRVTLVDVTRNTATIKWEKPESD 18950
Query: 262 NNERFKGFLHTWAGMSKPSSKNTEK--GLSSIKSYKANLNGMVISEDTVYKV 311
+ G+ + + +K +EK + +K+ +A ++G+ E+ V++V
Sbjct: 18951 GGSKITGY------VVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRV 18996
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 38.1 bits (87), Expect = 0.025
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 21/112 (18%)
Query: 213 GCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMT-----------SENQED 261
GC R+L + G+ LPA T P V++ P LPPG + + + + D
Sbjct: 18768 GCSYYFRVLASNEYGIGLPAETTEPVKVSE--PPLPPGRVTLVDVTRNTATIKWEKPESD 18825
Query: 262 NNERFKGFLHTWAGMSKPSSKNTEK--GLSSIKSYKANLNGMVISEDTVYKV 311
+ G+ + + +K +EK + +K+ +A ++G+ E+ V++V
Sbjct: 18826 GGSKITGY------VVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRV 18871
>gi|127138957 zinc finger protein 537 [Homo sapiens]
Length = 1081
Score = 37.4 bits (85), Expect = 0.042
Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 15/126 (11%)
Query: 372 NPAHILSLS--YDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMS 429
NP H+L L + +LR + I ++ ER S F L S + HW N+
Sbjct: 899 NPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGL----SMTTISHWLANVK 954
Query: 430 LVDRRTPGTSYEK---------LTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRL 480
RRT GT + K + +IRT + H + + LRD ++
Sbjct: 955 YQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRLRDLSKLSTEQI 1014
Query: 481 NSRRSQ 486
NS+ +Q
Sbjct: 1015 NSQIAQ 1020
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 37.4 bits (85), Expect = 0.042
Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 10/122 (8%)
Query: 407 SSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGK----IRTVHVHPVHRQ 462
+ DF D L G D + L PG + +G + + HP
Sbjct: 81 TDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVEVLQFHPTSDG 140
Query: 463 YFITAGLRDTHIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRI 522
++A ++DA + QPL L H + SA +S G V T C D LRI
Sbjct: 141 ILVSAAGTTVKVWDAAK-----QQPLTELAAHGDLVQSAVWSR-DGALVGTACKDKQLRI 194
Query: 523 FD 524
FD
Sbjct: 195 FD 196
Score = 32.0 bits (71), Expect = 1.8
Identities = 18/58 (31%), Positives = 28/58 (48%)
Query: 477 ARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPL 534
A L + P LT HT+ I S F PL N + ++ D +RI+D + ++ L
Sbjct: 576 AEGLEEVLTTPETVLTGHTEKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKL 633
>gi|38605733 nucleoporin 43kDa [Homo sapiens]
Length = 380
Score = 36.2 bits (82), Expect = 0.093
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 315 PIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPA 374
P+ + HP++ +VA G + G + + D+ Q V + H + ++F P+NP
Sbjct: 219 PLHCVDRHPNQQH-VVATGGQDGMLSIWDVRQGTMP--VSLLKAHEAEMWEVHFHPSNPE 275
Query: 375 HILSLSYDGTLRCGDFSRAIFEE 397
H+ + S DG+L D S + E+
Sbjct: 276 HLFTCSEDGSLWHWDASTDVPEK 298
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 36.2 bits (82), Expect = 0.093
Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 2/109 (1%)
Query: 183 SESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLVAD 242
S+ A + +R P + P+R G C S P GV PPT +
Sbjct: 71 SKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPT--TE 128
Query: 243 ETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSI 291
E PPG + SE + D+++ F + + P K + LS++
Sbjct: 129 EEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSAL 177
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 35.4 bits (80), Expect = 0.16
Identities = 33/143 (23%), Positives = 66/143 (46%), Gaps = 16/143 (11%)
Query: 93 IIPPKMKNTSSKAEST-LQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSDEDTT 151
++ + K + K +S LQ + + K + KR +++ +++ E + G+ +E+
Sbjct: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLE-EEEEGGEEEEEAA 138
Query: 152 ---PALDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSKRKKPKR 208
++ ++ +RK KN + F E RLRE E RQ ++K++K K
Sbjct: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE--ELRQEWEAKQEKIKS 196
Query: 209 E---------NGIGCRRSMRLLK 222
E +G G RR++++ K
Sbjct: 197 EEIEITFSYWDGSGHRRTVKMRK 219
>gi|23943912 phosphoinositide-3-kinase, regulatory subunit 4 [Homo
sapiens]
Length = 1358
Score = 35.0 bits (79), Expect = 0.21
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 14/117 (11%)
Query: 419 LIVGHWDGNMSLVDRR--TPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITA--GLRDTHI 474
L +G G M+ D R P +S+ S +IR + +HP+++ + I A G + +
Sbjct: 1156 LCIGTSSGTMACWDMRFQLPISSH---CHPSRARIRRLSMHPLYQSWVIAAVQGNNEVSM 1212
Query: 475 YDARRLNSR------RSQPLISLTEHTKSIASAYFSPLTGNRVVTTC-ADCNLRIFD 524
+D + R + PL L S+ Y SP GN ++ T +D +R +D
Sbjct: 1213 WDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAGSDMKIRFWD 1269
>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
Length = 638
Score = 35.0 bits (79), Expect = 0.21
Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 15/195 (7%)
Query: 322 HPSETRTLVAVGAKFGQVGLCDLTQQ---PKEDGVYVFHPHSQPVSCLYFSPANPAH-IL 377
HP+ LV G GQ+ L D P + H+ PV C+ AH ++
Sbjct: 344 HPN----LVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI 399
Query: 378 SLSYDG-----TLRCGDFSRAIFEEVYRNERS-SFSSFDFLAEDASTLIVGHWDGNMSLV 431
S+S DG +L + E V++ ++ + +S F D + +VG +G++
Sbjct: 400 SISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTA 459
Query: 432 DRRTPGTSYEKLTSSSMGKIRTVHVH-PVHRQYFITAGLRDTHIYDARRLNSRRSQPLIS 490
R ++ G I +H H V F + + + + ++ ++PL S
Sbjct: 460 CRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYS 519
Query: 491 LTEHTKSIASAYFSP 505
++ + +SP
Sbjct: 520 FEDNADYVYDVMWSP 534
>gi|4557757 MutL protein homolog 1 [Homo sapiens]
Length = 756
Score = 34.7 bits (78), Expect = 0.27
Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 22/220 (10%)
Query: 98 MKNTSSKAESTLQNSSSAVHTE----SNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPA 153
+K+T+S S+ SS V+ ++ + K A LS + S ED T
Sbjct: 360 VKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDI 419
Query: 154 LDFSGLSPYERKRLKNISENADFFASLQLSE--SAARLREMIEKRQPPKSKRKKPKRENG 211
SG + + + + + A+ A Q E + EM EKR P S +K RE+
Sbjct: 420 S--SGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDS 477
Query: 212 IGCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMTSENQEDNNERFKGFLH 271
+ +++ D S + AA TP + + T + L + E E +E + LH
Sbjct: 478 -----DVEMVE-DDSRKEMTAACTPRRRIINLTSV-----LSLQEEINEQGHEVLREMLH 526
Query: 272 TWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKV 311
S N + L+ ++ LN +SE+ Y++
Sbjct: 527 ---NHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQI 563
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 34.7 bits (78), Expect = 0.27
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 12/162 (7%)
Query: 359 HSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSR-----AIFEEVYRNERSSFSSFDFLA 413
H+ V+ + +P P ILS S D T+ +R I + R S F S ++
Sbjct: 14 HNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGH-SHFVSDVVIS 72
Query: 414 EDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTH 473
D + G WDG + L D T GT+ + + + +V +RQ I +G RD
Sbjct: 73 SDGQFALSGSWDGTLRLWD-LTTGTTTRRFVGHTK-DVLSVAFSSDNRQ--IVSGSRDKT 128
Query: 474 IYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTC 515
I L + + H++ ++ FSP + N ++ +C
Sbjct: 129 IKLWNTLGV--CKYTVQDESHSEWVSCVRFSPNSSNPIIVSC 168
>gi|219802034 nuclear factor related to kappaB binding protein
isoform 1 [Homo sapiens]
Length = 1299
Score = 34.7 bits (78), Expect = 0.27
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 181 QLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRS--MRLLKVDPSGVSLPAAPTPPT 238
Q +AA+ R+ ++++ P SK K +E+ I S ++ S S+P PTP T
Sbjct: 664 QAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMP--PTPVT 721
Query: 239 LVADETPLLPPGPL 252
V TP LP P+
Sbjct: 722 PVTPTTPALPAIPI 735
>gi|23346420 nuclear factor related to kappaB binding protein
isoform 2 [Homo sapiens]
Length = 1324
Score = 34.7 bits (78), Expect = 0.27
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 181 QLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRS--MRLLKVDPSGVSLPAAPTPPT 238
Q +AA+ R+ ++++ P SK K +E+ I S ++ S S+P PTP T
Sbjct: 689 QAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMP--PTPVT 746
Query: 239 LVADETPLLPPGPL 252
V TP LP P+
Sbjct: 747 PVTPTTPALPAIPI 760
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 34.7 bits (78), Expect = 0.27
Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 11/129 (8%)
Query: 83 KTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQ 142
+T K + + + ++T+++ +S LQ V + + R D +D S
Sbjct: 2624 ETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRGQDLGQAVLDAGHSV 2683
Query: 143 DGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSK 202
+ E T P L + LS E + + N ASL LS S R+RE+I + + SK
Sbjct: 2684 S--TLEKTLPQL-LAKLSILENRGVHN--------ASLALSASIGRVRELIAQARGAASK 2732
Query: 203 RKKPKRENG 211
K P + NG
Sbjct: 2733 VKVPMKFNG 2741
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 34.3 bits (77), Expect = 0.35
Identities = 37/154 (24%), Positives = 57/154 (37%), Gaps = 7/154 (4%)
Query: 70 LSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTES------NKL 123
LS + + K+ K + R P K K+ S + A S +K
Sbjct: 3 LSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT 62
Query: 124 QPKRTADAMNLSVDVESSQDGDSDEDTTPALDFSGLSPYERKRLKNISENADFFASLQLS 183
+ +R+A + + S SS S T+ SG S S + +S S
Sbjct: 63 RKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS-SGSSSSSASSRSGSSSTSRSSSSSSSS 121
Query: 184 ESAARLREMIEKRQPPKSKRKKPKRENGIGCRRS 217
S + R + R+ +SK K PKR+ RRS
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRS 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,364,409
Number of Sequences: 37866
Number of extensions: 1137257
Number of successful extensions: 4870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 4718
Number of HSP's gapped (non-prelim): 262
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.