Guide to the Human Genome
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Search of human proteins with 5174513

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   899   0.0  
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   825   0.0  
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   809   0.0  
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    809   0.0  
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   763   0.0  
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   680   0.0  
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]        563   e-160
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]        563   e-160
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]        563   e-160
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]             555   e-158
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]              555   e-158
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              555   e-158
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]            548   e-156
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   487   e-137
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]   272   4e-73
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]             139   4e-33
gi|5174517 SMAD family member 7 [Homo sapiens]                        127   3e-29
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            101   1e-21
gi|146134388 YLP motif containing 1 [Homo sapiens]                     35   0.17 
gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo ...    34   0.29 
gi|110611908 mitogen-activated protein kinase kinase kinase kina...    33   0.64 
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    33   0.64 
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    33   0.64 
gi|217416343 fibrosin-like 1 [Homo sapiens]                            32   0.84 
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]    32   1.1  
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]    32   1.1  
gi|157168329 formin 1 [Homo sapiens]                                   31   1.9  
gi|154689780 son of sevenless homolog 2 [Homo sapiens]                 31   1.9  
gi|34452173 integrin alpha X precursor [Homo sapiens]                  31   1.9  
gi|58219024 hypothetical protein LOC352999 [Homo sapiens]              31   2.4  

>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  899 bits (2324), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
           MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60

Query: 61  NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
           NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct: 61  NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120

Query: 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
           CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct: 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180

Query: 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
           PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct: 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240

Query: 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
           NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct: 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300

Query: 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
           GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct: 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360

Query: 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
           EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct: 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420

Query: 421 CSSVS 425
           CSSVS
Sbjct: 421 CSSVS 425


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  825 bits (2130), Expect = 0.0
 Identities = 392/437 (89%), Positives = 411/437 (94%), Gaps = 12/437 (2%)

Query: 1   MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
           MSSILPFTPP+VKRLLGWKK          GEQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 51  LEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE 110
           LEKAITTQN NTKC+TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE
Sbjct: 61  LEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE 120

Query: 111 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI 170
           +AFN+KKDEVCVNPYHYQRVETPVLPPVLVPRHTEI  E PPLDDY+HSIPENTNFPAGI
Sbjct: 121 YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI 180

Query: 171 EPQSN-IPETPPPGYLSEDGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCE 228
           EPQSN IPETPPPGY+SEDGETSD Q+N SMD GSP  LSP  +SP +++LDLQPVTY E
Sbjct: 181 EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE 240

Query: 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 288
           PAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRR
Sbjct: 241 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 300

Query: 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
           HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF
Sbjct: 301 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 360

Query: 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
           AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
Sbjct: 361 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 420

Query: 409 KVLTQMGSPSIRCSSVS 425
           KVLTQMGSPS+RCSS+S
Sbjct: 421 KVLTQMGSPSVRCSSMS 437


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  809 bits (2089), Expect = 0.0
 Identities = 392/467 (83%), Positives = 411/467 (88%), Gaps = 42/467 (8%)

Query: 1   MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
           MSSILPFTPP+VKRLLGWKK          GEQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 51  LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
           LEKAITTQN NTKC+TIP                              RSLDGRLQVSHR
Sbjct: 61  LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120

Query: 81  KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
           KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct: 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180

Query: 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
           PRHTEI  E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct: 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240

Query: 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
           MD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct: 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300

Query: 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
           GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct: 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360

Query: 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
           NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct: 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420

Query: 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  809 bits (2089), Expect = 0.0
 Identities = 392/467 (83%), Positives = 411/467 (88%), Gaps = 42/467 (8%)

Query: 1   MSSILPFTPPIVKRLLGWKK----------GEQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
           MSSILPFTPP+VKRLLGWKK          GEQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct: 1   MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60

Query: 51  LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
           LEKAITTQN NTKC+TIP                              RSLDGRLQVSHR
Sbjct: 61  LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120

Query: 81  KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
           KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct: 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180

Query: 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
           PRHTEI  E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct: 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240

Query: 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
           MD GSP  LSP  +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct: 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300

Query: 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
           GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct: 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360

Query: 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
           NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct: 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420

Query: 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  763 bits (1971), Expect = 0.0
 Identities = 359/366 (98%), Positives = 361/366 (98%)

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
           V+ K   + RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE
Sbjct: 16  VHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 75

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET 179
           VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET
Sbjct: 76  VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET 135

Query: 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
           PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE
Sbjct: 136 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 195

Query: 240 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 299
           LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI
Sbjct: 196 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 255

Query: 300 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 359
           GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG
Sbjct: 256 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 315

Query: 360 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 419
           FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI
Sbjct: 316 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 375

Query: 420 RCSSVS 425
           RCSSVS
Sbjct: 376 RCSSVS 381


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  680 bits (1755), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 106 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 165
           MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN
Sbjct: 1   MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60

Query: 166 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
           FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT
Sbjct: 61  FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120

Query: 226 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 285
           YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL
Sbjct: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180

Query: 286 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 345
           TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
Sbjct: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240

Query: 346 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 405
           QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
Sbjct: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300

Query: 406 WLDKVLTQMGSPSIRCSSVS 425
           WLDKVLTQMGSPSIRCSSVS
Sbjct: 301 WLDKVLTQMGSPSIRCSSVS 320


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  563 bits (1451), Expect = e-160
 Identities = 284/468 (60%), Positives = 336/468 (71%), Gaps = 49/468 (10%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           M+S+  FT P VKRLLGWK+G++   EEKW EKAV +LVKKLKK  G ++ELEKA+++  
Sbjct: 4   MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F  K+ E
Sbjct: 61  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
           VC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      +P+N  FP      
Sbjct: 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180

Query: 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
           +N P                                   +TPPP Y+  D +      + 
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239

Query: 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
            MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VD
Sbjct: 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297

Query: 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
           GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct: 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357

Query: 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
            NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct: 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417

Query: 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  563 bits (1451), Expect = e-160
 Identities = 284/468 (60%), Positives = 336/468 (71%), Gaps = 49/468 (10%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           M+S+  FT P VKRLLGWK+G++   EEKW EKAV +LVKKLKK  G ++ELEKA+++  
Sbjct: 4   MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F  K+ E
Sbjct: 61  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
           VC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      +P+N  FP      
Sbjct: 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180

Query: 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
           +N P                                   +TPPP Y+  D +      + 
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239

Query: 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
            MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VD
Sbjct: 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297

Query: 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
           GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct: 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357

Query: 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
            NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct: 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417

Query: 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score =  563 bits (1451), Expect = e-160
 Identities = 284/468 (60%), Positives = 336/468 (71%), Gaps = 49/468 (10%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           M+S+  FT P VKRLLGWK+G++   EEKW EKAV +LVKKLKK  G ++ELEKA+++  
Sbjct: 4   MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F  K+ E
Sbjct: 61  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
           VC+NPYHY+RVE+PVLPPVLVPRH E      +  +F  L      +P+N  FP      
Sbjct: 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180

Query: 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
           +N P                                   +TPPP Y+  D +      + 
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239

Query: 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
            MD  S N+ P  M P+ ++ D+QPV Y EP  WCSI YYELN RVGE FHAS  S+ VD
Sbjct: 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297

Query: 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
           GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct: 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357

Query: 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
            NCN  +G+HP TVCKIP  C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct: 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417

Query: 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  555 bits (1431), Expect = e-158
 Identities = 286/471 (60%), Positives = 333/471 (70%), Gaps = 54/471 (11%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           ++S+  FT P VKRLLGWK+G++   EEKW EKAV +LVKKLKK  G ++ELEKA++   
Sbjct: 3   VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             + C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ E
Sbjct: 60  QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
           VC+NPYHY+RVE+PVLPPVLVPRH+E      + A+F  L      +P N  FP   +  
Sbjct: 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179

Query: 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
                   P S+ P                           +TPPP YL  ED  T D  
Sbjct: 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG- 238

Query: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
            +  MD    N+   P+    N  D+Q V Y EP  WCSI YYELN RVGE FHAS  S+
Sbjct: 239 -SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294

Query: 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
            VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct: 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354

Query: 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
           VQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct: 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414

Query: 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score =  555 bits (1431), Expect = e-158
 Identities = 286/471 (60%), Positives = 333/471 (70%), Gaps = 54/471 (11%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           ++S+  FT P VKRLLGWK+G++   EEKW EKAV +LVKKLKK  G ++ELEKA++   
Sbjct: 3   VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             + C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ E
Sbjct: 60  QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
           VC+NPYHY+RVE+PVLPPVLVPRH+E      + A+F  L      +P N  FP   +  
Sbjct: 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179

Query: 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
                   P S+ P                           +TPPP YL  ED  T D  
Sbjct: 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG- 238

Query: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
            +  MD    N+   P+    N  D+Q V Y EP  WCSI YYELN RVGE FHAS  S+
Sbjct: 239 -SQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294

Query: 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
            VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct: 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354

Query: 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
           VQS NCN  +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct: 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414

Query: 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  555 bits (1429), Expect = e-158
 Identities = 277/436 (63%), Positives = 331/436 (75%), Gaps = 23/436 (5%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           +SS+  FT P VKRLLGWK+G++   EEKW EKAV SLVKKLKK  G +DELE+A++   
Sbjct: 7   ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ E
Sbjct: 64  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE- 171
           VC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS   +P N  +P   + 
Sbjct: 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183

Query: 172 -PQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
            P S +P +P   +       S    ++    GSP+    P SP + + D +PV Y EP 
Sbjct: 184 PPCSALPPSPSHAF-----SQSPCTASYPHSPGSPS---EPESP-YQHSDFRPVCYEEPQ 234

Query: 231 FWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRH 289
            WCS++YYELN RVGETF AS  S+ +DGFTDPSN+  RFCLGLLSNVNRN+ +E TRRH
Sbjct: 235 HWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRH 294

Query: 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 349
           IG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA
Sbjct: 295 IGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFA 354

Query: 350 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 409
            LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDK
Sbjct: 355 QLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDK 414

Query: 410 VLTQMGSPSIRCSSVS 425
           VLTQMGSP    SSVS
Sbjct: 415 VLTQMGSPHNPISSVS 430


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score =  548 bits (1411), Expect = e-156
 Identities = 281/465 (60%), Positives = 335/465 (72%), Gaps = 44/465 (9%)

Query: 1   MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
           +SS+  FT P VKRLLGWK+G++   EEKW EKAV SLVKKLKK  G +DELE+A++   
Sbjct: 7   ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63

Query: 60  VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
             +KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F  K+ E
Sbjct: 64  QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123

Query: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE- 171
           VC+NPYHY+RVETPVLPPVLVPRH+E   +   L  +     HS   +P N  +P   + 
Sbjct: 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183

Query: 172 -PQSNIPETPP---------------PGYLSEDGETSDHQMN------HSMDAGSPNLSP 209
            P S +P +P                PG  SE      H ++      H+ +A S   S 
Sbjct: 184 PPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEA-SETQSG 242

Query: 210 NPMSPAHN--------NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT 261
            P+    +        N D +PV Y EP  WCS++YYELN RVGETF AS  S+ +DGFT
Sbjct: 243 QPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302

Query: 262 DPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNC 320
           DPSN+  RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NC
Sbjct: 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362

Query: 321 NQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGW 380
           N ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGW
Sbjct: 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422

Query: 381 GAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           GAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP    SSVS
Sbjct: 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score =  487 bits (1253), Expect = e-137
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
           MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 1   MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60

Query: 256 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
           TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 61  TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120

Query: 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
           QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180

Query: 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
           FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score =  272 bits (696), Expect = 4e-73
 Identities = 189/518 (36%), Positives = 253/518 (48%), Gaps = 128/518 (24%)

Query: 23  QNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
           Q G+ E + ++A++SLVKKLK K  +LD L  AITT   + +KC+TI R+LDGRLQV+ R
Sbjct: 28  QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87

Query: 81  KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
           KG PHVIY RLWRWPDLH  +EL+ ++ C++AF++K D VCVNPYHY+RV +P +    +
Sbjct: 88  KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146

Query: 141 PRHTEIPAEFPPLDDYSHSI-------------------PEN------------------ 163
              +  P+     D+Y H                     P N                  
Sbjct: 147 TLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSES 206

Query: 164 ---------------TNFPAGI------EPQSNIPETPPPGYLSEDGETSD----HQMNH 198
                          T+ PA I      E    I   P PG   ++G T      H  + 
Sbjct: 207 NATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQ-QQNGFTGQPATYHHNST 265

Query: 199 SMDAGSPNLSPNPMSPAHNNLDLQ----------------------PVTYCEPA--FWCS 234
           +   GS      P  P H N  LQ                      P     PA  +WCS
Sbjct: 266 TTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCS 325

Query: 235 ISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGR 292
           I+Y+E++ +VGETF   +S P +TVDG+ DPS  +RFCLG LSNV+R  A+E  R HIG+
Sbjct: 326 IAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGK 385

Query: 293 GVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN------ 344
           GV+L   G G+V+  CLSD A+FVQS   ++  G  P   V KI P   +K+F+      
Sbjct: 386 GVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHR 445

Query: 345 --NQEFAALLAQSVNQGFE--------------------------AVYQLTRMCTIRMSF 376
              Q+ A   A +  Q                              V  L R+C +RMSF
Sbjct: 446 QMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSF 505

Query: 377 VKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
           VKGWG +Y RQ++  TPCWIE+HL+  LQ LD+VL  M
Sbjct: 506 VKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score =  139 bits (351), Expect = 4e-33
 Identities = 114/371 (30%), Positives = 174/371 (46%), Gaps = 57/371 (15%)

Query: 37  SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWP 95
           SL+K+LK+   LD L +A+ ++  V   C+ +PR+    L++  +   P ++  RL+RWP
Sbjct: 178 SLLKRLKERS-LDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRWP 233

Query: 96  DLHSHHELRAMELCE-FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPA--EFPP 152
           DL    EL+ +  C  FA       VC NPYH+ R+  P  PP   P ++ +    E+ P
Sbjct: 234 DLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPRDEYKP 290

Query: 153 LDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPM 212
           LD     + ++T      E  +++   P        GE SD  M           SP+  
Sbjct: 291 LD-----LSDSTLSYTETEATNSLITAP--------GEFSDASM-----------SPDAT 326

Query: 213 SPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLG 272
            P+H               WCS++Y+E   RVG  +     ++++  F D      FCLG
Sbjct: 327 KPSH---------------WCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLG 369

Query: 273 LLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVC 332
            L+   R+ +V  TR  IG G+ L      V+A    +  IFV SP  +   G     V 
Sbjct: 370 QLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVR 428

Query: 333 KIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTST 392
           K+PPG ++K+F + E + L         +  Y      ++R+SF KGWG  Y RQ +TS 
Sbjct: 429 KVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN---SVRISFAKGWGPCYSRQFITSC 484

Query: 393 PCWIELHLNGP 403
           PCW+E+ LN P
Sbjct: 485 PCWLEILLNNP 495


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score =  127 bits (318), Expect = 3e-29
 Identities = 108/377 (28%), Positives = 177/377 (46%), Gaps = 62/377 (16%)

Query: 37  SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLP 84
           S++KKLK+  QL+ L +A+ ++    T C+ +P  LD RL           Q      LP
Sbjct: 98  SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156

Query: 85  HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144
            ++ C+++RWPDL    E++ +  CE    +  + VC NP+H  R+     PP   P ++
Sbjct: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYS 212

Query: 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
             P +F                   ++P ++ P+  P        ET           G+
Sbjct: 213 RYPMDF-------------------LKPTADCPDAVP-----SSAET----------GGT 238

Query: 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264
             L+P  +S   + L L+P    + + WC ++Y+E   RVG  +   +PS+  D F D  
Sbjct: 239 NYLAPGGLS--DSQLLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLP 291

Query: 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324
               FCLG L++ N++  V+  R  IG G++L      V+    S   IF++S   +   
Sbjct: 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351

Query: 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384
                 V K+ PG ++K F+ ++  +L  Q  N   E + Q     T+++SFVKGWG  Y
Sbjct: 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407

Query: 385 RRQTVTSTPCWIELHLN 401
            RQ ++S PCW+E+  N
Sbjct: 408 TRQFISSCPCWLEVIFN 424


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score =  101 bits (252), Expect = 1e-21
 Identities = 74/235 (31%), Positives = 115/235 (48%), Gaps = 21/235 (8%)

Query: 178 ETPPPGY--LSEDGE-----TSDHQMNHSMDAGSPNL--SPNPMSPAHNNLDLQPVTYCE 228
           ++PPP Y  LS   E      SD  ++++    + +L  +P   S A  + D       +
Sbjct: 12  KSPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDAT-----K 66

Query: 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 288
           P+ WCS++Y+E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR 
Sbjct: 67  PSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRS 124

Query: 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
            IG G+ L      V+A    +  IFV SP  +   G     V K+PPG ++K+F+ +  
Sbjct: 125 KIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERS 183

Query: 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
               A   +   +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 184 GLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 19/50 (38%), Positives = 22/50 (44%)

Query: 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYL 185
           PP LVP   E P E PP+   S+  P  +  P    P S  P T    YL
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYL 184



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 23/103 (22%), Positives = 36/103 (34%), Gaps = 6/103 (5%)

Query: 128 QRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE 187
           Q++    +  VL P H   P   PP       +     +     P   +P  P P    +
Sbjct: 65  QQMHQKQMQCVLQPHHLPPPPLPPP------PVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118

Query: 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
             +   HQM H    G P L P  +     +  + P +Y  P+
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPS 161


>gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo
           sapiens]
          Length = 176

 Score = 33.9 bits (76), Expect = 0.29
 Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 10/94 (10%)

Query: 121 CVNPYHYQRVETPVLPPVLVPR---HTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP 177
           C  P+  +R  T  LPP L P    H+  P    P    +   P+    PA + PQ   P
Sbjct: 75  CTQPHRRRRRGTRRLPPALTPAGPYHSARPGGGGPCQGSARFSPD----PAAVRPQ---P 127

Query: 178 ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNP 211
             P P   S      D +   ++  G+P  SP P
Sbjct: 128 RGPQPDSGSARQVPPDSRGAQALHRGAPLASPAP 161


>gi|110611908 mitogen-activated protein kinase kinase kinase kinase
           1 isoform 1 [Homo sapiens]
          Length = 821

 Score = 32.7 bits (73), Expect = 0.64
 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 30/202 (14%)

Query: 35  VKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRK---GLPHVIYCRL 91
           +  L+ KLK  G      K  +  ++  +   +P ++  R++ +HR    G+P    CR 
Sbjct: 284 ILDLLDKLKNPG------KGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCR- 336

Query: 92  WRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP 151
                   H E R +   E             P +  R++ P       PR     +   
Sbjct: 337 -------RHMEFRKLRGMETR----------PPANTARLQPPRDLRSSSPRKQLSESSDD 379

Query: 152 PLDDYSHSIP-ENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPN 210
             DD     P E+T  P   +P+   P    PG + +DG+ S   +        PN SP 
Sbjct: 380 DYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPN-SPR 438

Query: 211 PMSPAHNNLDLQPVTYCEPAFW 232
           P  P  +        + EP+ W
Sbjct: 439 P-GPPPSTSSPHLTAHSEPSLW 459


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 32.7 bits (73), Expect = 0.64
 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 30/202 (14%)

Query: 35  VKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRK---GLPHVIYCRL 91
           +  L+ KLK  G      K  +  ++  +   +P ++  R++ +HR    G+P    CR 
Sbjct: 284 ILDLLDKLKNPG------KGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCR- 336

Query: 92  WRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP 151
                   H E R +   E             P +  R++ P       PR     +   
Sbjct: 337 -------RHMEFRKLRGMETR----------PPANTARLQPPRDLRSSSPRKQLSESSDD 379

Query: 152 PLDDYSHSIP-ENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPN 210
             DD     P E+T  P   +P+   P    PG + +DG+ S   +        PN SP 
Sbjct: 380 DYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPN-SPR 438

Query: 211 PMSPAHNNLDLQPVTYCEPAFW 232
           P  P  +        + EP+ W
Sbjct: 439 P-GPPPSTSSPHLTAHSEPSLW 459


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 32.7 bits (73), Expect = 0.64
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 15/99 (15%)

Query: 131  ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN--IPETPPPGYLSED 188
            E P LPP  +P  T IP+  PP        P ++  P   +P+    +PE P  G  S  
Sbjct: 1525 EPPGLPPASLPESTPIPSSSPP--------PLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576

Query: 189  GE-----TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 222
             E     T +     S   G   +S +    AHN   L+
Sbjct: 1577 LELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLR 1615


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 32.3 bits (72), Expect = 0.84
 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 13/103 (12%)

Query: 124 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS-------HSIPENTNFPAGIEPQSNI 176
           P+ +     P  P  L+P H  +PA       +S       H +  +++ P G+    ++
Sbjct: 294 PHRHTPQPPPPQPRGLLPTH--VPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSL 351

Query: 177 PETPPPGYLSEDG----ETSDHQMNHSMDAGSPNLSPNPMSPA 215
               P  +LS         + HQ++ +M A  P L P P  PA
Sbjct: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPA 394


>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
          Length = 922

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)

Query: 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
           PP     H  +P   PP   ++   P   N  AG+ P +N+   PPP Y      T +  
Sbjct: 167 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 225

Query: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
           ++            NP  P  N     P +
Sbjct: 226 LS------------NPSKPIQNQTFSTPAS 243


>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
          Length = 944

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)

Query: 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
           PP     H  +P   PP   ++   P   N  AG+ P +N+   PPP Y      T +  
Sbjct: 189 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 247

Query: 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
           ++            NP  P  N     P +
Sbjct: 248 LS------------NPSKPIQNQTFSTPAS 265


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 34/136 (25%), Positives = 45/136 (33%), Gaps = 24/136 (17%)

Query: 133 PVLPPVLVPRHTEIPAEFPPLDDYSHS-IPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
           P  PP L P  +  P   PP     +S  P N   P    P   +   PPPG     G +
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSS 743

Query: 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 251
           S               S  P  PA     ++P    +P +W  I   + +Q    T    
Sbjct: 744 S---------------SQCPRKPA-----IEPSCPMKPLYWTRIQISDRSQNATPTL--- 780

Query: 252 QPSMTVDGFTDPSNSE 267
             S+      DPS  E
Sbjct: 781 WDSLEEPDIRDPSEFE 796


>gi|154689780 son of sevenless homolog 2 [Homo sapiens]
          Length = 1332

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 10/93 (10%)

Query: 136  PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
            PP + PR    P   P +   + +     + P    P+  +P+TPPP  L       +H 
Sbjct: 1172 PPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPL----RPPEHF 1227

Query: 196  MNHSMDAGSPNLSPNPMSPAHNNLD-LQPVTYC 227
            +N        NL P P+   H + D L+ ++ C
Sbjct: 1228 INCPF-----NLQPPPLGHLHRDSDWLRDISTC 1255


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 13/39 (33%), Positives = 21/39 (53%)

Query: 385  RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 423
            +R    S   W+ + LN    W+D  ++   +PS+RCSS
Sbjct: 962  QRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSS 1000


>gi|58219024 hypothetical protein LOC352999 [Homo sapiens]
          Length = 330

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 13/36 (36%), Positives = 22/36 (61%)

Query: 165 NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 200
           +F A +   SN+ ET PP +    G+ SD+++ +SM
Sbjct: 14  SFSASLAGTSNLSETEPPLWKESPGQLSDYRVENSM 49


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,473,267
Number of Sequences: 37866
Number of extensions: 1015736
Number of successful extensions: 2969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2867
Number of HSP's gapped (non-prelim): 88
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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