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Search of human proteins with 51477696
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51477696 parvin, beta isoform a [Homo sapiens]
(397 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51477696 parvin, beta isoform a [Homo sapiens] 792 0.0
gi|20127528 parvin, beta isoform b [Homo sapiens] 646 0.0
gi|8922673 parvin, alpha [Homo sapiens] 495 e-140
gi|212286181 parvin, gamma [Homo sapiens] 261 6e-70
gi|212286179 parvin, gamma [Homo sapiens] 261 6e-70
gi|11545879 parvin, gamma [Homo sapiens] 261 6e-70
gi|12025678 actinin, alpha 4 [Homo sapiens] 48 2e-05
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 47 4e-05
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 47 4e-05
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 47 4e-05
gi|4557241 actinin, alpha 3 [Homo sapiens] 46 5e-05
gi|4501893 actinin, alpha 2 [Homo sapiens] 44 2e-04
gi|221316618 dystonin isoform 2 [Homo sapiens] 44 2e-04
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 43 4e-04
gi|221316624 dystonin isoform 4 [Homo sapiens] 43 6e-04
gi|221316622 dystonin isoform 3 [Homo sapiens] 43 6e-04
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 42 7e-04
gi|33188445 microfilament and actin filament cross-linker protei... 42 0.001
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 42 0.001
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 41 0.002
gi|188595687 gamma filamin isoform b [Homo sapiens] 40 0.003
gi|116805322 gamma filamin isoform a [Homo sapiens] 40 0.003
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 40 0.005
gi|34577047 dystonin isoform 1 [Homo sapiens] 39 0.006
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 39 0.006
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 39 0.006
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 39 0.008
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 39 0.008
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 39 0.008
gi|67782321 spectrin beta isoform a [Homo sapiens] 39 0.011
>gi|51477696 parvin, beta isoform a [Homo sapiens]
Length = 397
Score = 792 bits (2046), Expect = 0.0
Identities = 397/397 (100%), Positives = 397/397 (100%)
Query: 1 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG 60
MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG
Sbjct: 1 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG 60
Query: 61 VETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFK 120
VETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFK
Sbjct: 61 VETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFK 120
Query: 121 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ 180
ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ
Sbjct: 121 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ 180
Query: 181 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV 240
KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV
Sbjct: 181 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV 240
Query: 241 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH 300
VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH
Sbjct: 241 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH 300
Query: 301 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML 360
LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML
Sbjct: 301 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML 360
Query: 361 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE 397
DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
Sbjct: 361 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE 397
>gi|20127528 parvin, beta isoform b [Homo sapiens]
Length = 364
Score = 646 bits (1667), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 71 VSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI 130
VSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI
Sbjct: 38 VSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI 97
Query: 131 NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH 190
NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH
Sbjct: 98 NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH 157
Query: 191 DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 250
DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL
Sbjct: 158 DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 217
Query: 251 HSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTE 310
HSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTE
Sbjct: 218 HSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTE 277
Query: 311 LETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKAR 370
LETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKAR
Sbjct: 278 LETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKAR 337
Query: 371 PEDVVNLDLKSTLRVLYNLFTKYKNVE 397
PEDVVNLDLKSTLRVLYNLFTKYKNVE
Sbjct: 338 PEDVVNLDLKSTLRVLYNLFTKYKNVE 364
>gi|8922673 parvin, alpha [Homo sapiens]
Length = 372
Score = 495 bits (1275), Expect = e-140
Identities = 248/327 (75%), Positives = 285/327 (87%)
Query: 71 VSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWI 130
VS+LQEEG NAIN P+SP ++ PEDT LEENE RTM+DP S+ DPK +EL+KVL+DWI
Sbjct: 46 VSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWI 105
Query: 131 NDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVH 190
NDVLV ERIIVK L EDLYDGQVLQKL EKL KLNVAEVTQSEI QKQKLQTVLE ++
Sbjct: 106 NDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKIN 165
Query: 191 DLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 250
+ L+ +++W+VDS+H K+LVAILHLLV+L+ +FRAPIRLP+HV++QVVVV+KREG+L
Sbjct: 166 ETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGIL 225
Query: 251 HSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTE 310
S I EE+T TE + GR ERDAFDTLFDHAPDKL+VVKK+LITFVNKHLNKLNLEVTE
Sbjct: 226 QSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTE 285
Query: 311 LETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKAR 370
LETQFADGVYLVLLMGLLE YFVPLH F+LTP+SF+QKV NVSFAFELM DGGL+KPK R
Sbjct: 286 LETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPR 345
Query: 371 PEDVVNLDLKSTLRVLYNLFTKYKNVE 397
PED+VN DLKSTLRVLYNLFTKY+NVE
Sbjct: 346 PEDIVNCDLKSTLRVLYNLFTKYRNVE 372
>gi|212286181 parvin, gamma [Homo sapiens]
Length = 331
Score = 261 bits (668), Expect = 6e-70
Identities = 136/301 (45%), Positives = 198/301 (65%), Gaps = 5/301 (1%)
Query: 95 PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 154
P + +L + ++ + PTS++DPKF+EL KVL++WIN L+ E I+V+ LEED++DG +L
Sbjct: 19 PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
Query: 155 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 214
L ++LA KL ++ + QK KL VLEAV+ L+ W +WSV+SI K+L++
Sbjct: 79 HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
Query: 215 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFE--R 272
LHLLV+LA F+ + LP +V V+V+ + + L S + E+L TE + E +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
Query: 273 DAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYF 332
D FD LF AP+K++ VK++++ FVN+ L++L L V L+TQFADGV L+LL+G LE +F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
Query: 333 VPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
+ L FYLTP S + +HNV+ A EL+ D GL PED+VN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
Query: 393 Y 393
+
Sbjct: 316 H 316
>gi|212286179 parvin, gamma [Homo sapiens]
Length = 331
Score = 261 bits (668), Expect = 6e-70
Identities = 136/301 (45%), Positives = 198/301 (65%), Gaps = 5/301 (1%)
Query: 95 PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 154
P + +L + ++ + PTS++DPKF+EL KVL++WIN L+ E I+V+ LEED++DG +L
Sbjct: 19 PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
Query: 155 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 214
L ++LA KL ++ + QK KL VLEAV+ L+ W +WSV+SI K+L++
Sbjct: 79 HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
Query: 215 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFE--R 272
LHLLV+LA F+ + LP +V V+V+ + + L S + E+L TE + E +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
Query: 273 DAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYF 332
D FD LF AP+K++ VK++++ FVN+ L++L L V L+TQFADGV L+LL+G LE +F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
Query: 333 VPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
+ L FYLTP S + +HNV+ A EL+ D GL PED+VN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
Query: 393 Y 393
+
Sbjct: 316 H 316
>gi|11545879 parvin, gamma [Homo sapiens]
Length = 331
Score = 261 bits (668), Expect = 6e-70
Identities = 136/301 (45%), Positives = 198/301 (65%), Gaps = 5/301 (1%)
Query: 95 PEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVL 154
P + +L + ++ + PTS++DPKF+EL KVL++WIN L+ E I+V+ LEED++DG +L
Sbjct: 19 PAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLIL 78
Query: 155 QKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVA 214
L ++LA KL ++ + QK KL VLEAV+ L+ W +WSV+SI K+L++
Sbjct: 79 HHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLS 138
Query: 215 ILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFE--R 272
LHLLV+LA F+ + LP +V V+V+ + + L S + E+L TE + E +
Sbjct: 139 TLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQL---TEYSTDKDEPPK 195
Query: 273 DAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYF 332
D FD LF AP+K++ VK++++ FVN+ L++L L V L+TQFADGV L+LL+G LE +F
Sbjct: 196 DVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFF 255
Query: 333 VPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
+ L FYLTP S + +HNV+ A EL+ D GL PED+VN D KSTLRVLY LF K
Sbjct: 256 LHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCK 315
Query: 393 Y 393
+
Sbjct: 316 H 316
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ ++ F DG+ L+LL+ ++ +P
Sbjct: 41 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLP- 97
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
PE +VH NV+ A + + G+K E++V+ + K TL +++ + +
Sbjct: 98 -----KPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILR 152
Query: 393 Y 393
+
Sbjct: 153 F 153
Score = 28.9 bits (63), Expect = 8.5
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 116 DPKF-KELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQS 174
DP + K+ K W N L + ++ ++ED DG L LLE ++G +L E +
Sbjct: 45 DPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKM 104
Query: 175 EIGQKQKLQTVLEAV 189
+ + + L+ +
Sbjct: 105 RVHKINNVNKALDFI 119
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ +E F DG+ L+LL+ ++
Sbjct: 22 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
PE +VH NV+ A + + G+K E++V+ ++K TL +++ + +
Sbjct: 75 -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133
Query: 393 Y 393
+
Sbjct: 134 F 134
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 99 QLEENEERTMI-DPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKL 157
Q EE+ +R ++ DP ++ + K W N L + ++ +EED DG L L
Sbjct: 14 QPEEDWDRDLLLDPAWEKQQR-----KTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLL 68
Query: 158 LEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAV 189
LE ++G +L E + + + + L+ +
Sbjct: 69 LEVISGERLAKPERGKMRVHKISNVNKALDFI 100
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ +E F DG+ L+LL+ ++
Sbjct: 22 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
PE +VH NV+ A + + G+K E++V+ ++K TL +++ + +
Sbjct: 75 -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133
Query: 393 Y 393
+
Sbjct: 134 F 134
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 99 QLEENEERTMI-DPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKL 157
Q EE+ +R ++ DP ++ + K W N L + ++ +EED DG L L
Sbjct: 14 QPEEDWDRDLLLDPAWEKQQR-----KTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLL 68
Query: 158 LEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAV 189
LE ++G +L E + + + + L+ +
Sbjct: 69 LEVISGERLAKPERGKMRVHKISNVNKALDFI 100
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/121 (25%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ +E F DG+ L+LL+ ++
Sbjct: 22 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISG----- 74
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
PE +VH NV+ A + + G+K E++V+ ++K TL +++ + +
Sbjct: 75 -ERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 133
Query: 393 Y 393
+
Sbjct: 134 F 134
Score = 30.8 bits (68), Expect = 2.2
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 99 QLEENEERTMI-DPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKL 157
Q EE+ +R ++ DP ++ + K W N L + ++ +EED DG L L
Sbjct: 14 QPEEDWDRDLLLDPAWEKQQR-----KTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLL 68
Query: 158 LEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAV 189
LE ++G +L E + + + + L+ +
Sbjct: 69 LEVISGERLAKPERGKMRVHKISNVNKALDFI 100
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 46.2 bits (108), Expect = 5e-05
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ +E F +G+ L+LL+ ++ +P
Sbjct: 36 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLP- 92
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
P+ + H NV+ A + + G+K E++V+ +LK TL +++ + +
Sbjct: 93 -----RPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILR 147
Query: 393 Y 393
+
Sbjct: 148 F 148
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/121 (23%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L D A +K +K+ + N HL K ++ +E F +G+ L+LL+ ++ +P
Sbjct: 29 DLLLDPAWEKQQ--RKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLP- 85
Query: 336 HHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTK 392
P+ + H NV+ A + + G+K E++V+ ++K TL +++ + +
Sbjct: 86 -----KPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILR 140
Query: 393 Y 393
+
Sbjct: 141 F 141
Score = 30.0 bits (66), Expect = 3.8
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Query: 93 VHPEDTQLEENEE---RTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLY 149
V+ ED + + EE ++DP ++ + K W N L + ++ +EED
Sbjct: 13 VYDEDEYMIQEEEWDRDLLLDPAWEKQQR-----KTFTAWCNSHLRKAGTQIENIEEDFR 67
Query: 150 DGQVLQKLLEKLAGCKL 166
+G L LLE ++G +L
Sbjct: 68 NGLKLMLLLEVISGERL 84
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 44.3 bits (103), Expect = 2e-04
Identities = 57/209 (27%), Positives = 87/209 (41%), Gaps = 23/209 (11%)
Query: 54 PGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEER-----TM 108
P S + S + SD E+ + + SPA D P + E +R ++
Sbjct: 139 PSSGNASYRCSMSSSADFSD--EDDFSQKSGSASPAPGDTLPWNLPKHERSKRKIQGGSV 196
Query: 109 IDPTSKE-----DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAG 163
+DP + D + K K WIN L++ R V L EDL DG L LLE L+G
Sbjct: 197 LDPAERAVLRIADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG 256
Query: 164 CKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVS 221
+ E G+ + +LQ V A+ L R + + D I N L L+ +
Sbjct: 257 ------DTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWT 310
Query: 222 LAMHFRAPIRLPEHVTVQVVVVRKREGLL 250
+ +HF+ HVT + + +E LL
Sbjct: 311 IILHFQIS---DIHVTGESEDMSAKERLL 336
Score = 37.0 bits (84), Expect = 0.031
Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 282 APDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLT 341
A ++ V KK+ ++N+HL K+ V +L DG L+ L+ +L +P +
Sbjct: 208 ADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMR 267
Query: 342 PESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
++ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 268 ----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 316
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 43.1 bits (100), Expect = 4e-04
Identities = 30/111 (27%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 120 KELVKVLLDWINDVLVEERII--VKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIG 177
++ ++ + W+N L + + V+ L +DL DG +L L+E +AG KL+ +++ G
Sbjct: 20 EQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSP---G 76
Query: 178 QKQKLQTVLEAVHDLLRPRGWAL-RWSVDSIHGKNLVAILHLLVSLAMHFR 227
+Q+++ +E V + + + + S I NL +I+ L+++LA HF+
Sbjct: 77 NQQEMKNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFK 127
Score = 30.8 bits (68), Expect = 2.2
Identities = 24/106 (22%), Positives = 49/106 (46%), Gaps = 4/106 (3%)
Query: 291 KSLITFVNKHLNKLNL--EVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQK 348
++ + +VN L K V +L DGV L L+ ++ L L+P + +
Sbjct: 24 QAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGE--KLSGVQLSPGNQQEM 81
Query: 349 VHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
+NV + + ++ + +D+V+ +LKS +R++ L +K
Sbjct: 82 KNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFK 127
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 42.7 bits (99), Expect = 6e-04
Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 21/176 (11%)
Query: 87 SPALVDVHPEDTQLEENEER-----TMIDPTSKE-----DPKFKELVKVLLDWINDVLVE 136
SPA D P + E +R +++DP + D + K K WIN L++
Sbjct: 21 SPAPGDTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFTKWINQHLMK 80
Query: 137 ERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLR 194
R V L EDL DG L LLE L+G + E G+ + +LQ V A+ L R
Sbjct: 81 VRKHVNDLYEDLRDGHNLISLLEVLSG------DTLPREKGRMRFHRLQNVQIALDYLKR 134
Query: 195 PRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 250
+ + D I N L L+ ++ +HF+ HVT + + +E LL
Sbjct: 135 RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS---DIHVTGESEDMSAKERLL 187
Score = 37.0 bits (84), Expect = 0.031
Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 282 APDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLT 341
A ++ V KK+ ++N+HL K+ V +L DG L+ L+ +L +P +
Sbjct: 59 ADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMR 118
Query: 342 PESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
++ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 119 ----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 167
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 42.7 bits (99), Expect = 6e-04
Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 21/176 (11%)
Query: 87 SPALVDVHPEDTQLEENEER-----TMIDPTSKE-----DPKFKELVKVLLDWINDVLVE 136
SPA D P + E +R +++DP + D + K K WIN L++
Sbjct: 32 SPAPGDTLPWNLPKHERSKRKIQGGSVLDPAERAVLRIADERDKVQKKTFTKWINQHLMK 91
Query: 137 ERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLR 194
R V L EDL DG L LLE L+G + E G+ + +LQ V A+ L R
Sbjct: 92 VRKHVNDLYEDLRDGHNLISLLEVLSG------DTLPREKGRMRFHRLQNVQIALDYLKR 145
Query: 195 PRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLL 250
+ + D I N L L+ ++ +HF+ HVT + + +E LL
Sbjct: 146 RQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS---DIHVTGESEDMSAKERLL 198
Score = 37.0 bits (84), Expect = 0.031
Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 282 APDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLT 341
A ++ V KK+ ++N+HL K+ V +L DG L+ L+ +L +P +
Sbjct: 70 ADERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMR 129
Query: 342 PESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
++ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 130 ----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 178
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 42.4 bits (98), Expect = 7e-04
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 12/128 (9%)
Query: 270 FERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLE 329
FER L D ++ +V KK+ +VN HL +++ +T+L T DG L+ L+ +L
Sbjct: 40 FERSRIKALAD---EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLS 96
Query: 330 DYFVPLHHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVL 386
+P P ++H NV A + + + + D+V+ + + TL ++
Sbjct: 97 GERLP------KPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLI 150
Query: 387 YNLFTKYK 394
+ + +++
Sbjct: 151 WTIILRFQ 158
Score = 32.3 bits (72), Expect = 0.77
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 124 KVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKL 166
K W+N L + L DL DG++L KLLE L+G +L
Sbjct: 58 KTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL 100
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/155 (28%), Positives = 70/155 (45%), Gaps = 19/155 (12%)
Query: 84 SPMSPALVDVHPEDTQLEENEER----TMIDPTSKE-----DPKFKELVKVLLDWINDVL 134
SP P D P + L E ++R +++DP + D + + K W+N L
Sbjct: 35 SPCPPG--DTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHL 92
Query: 135 VEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDL 192
++ R + L EDL DG L LLE L+G KL E G+ + +LQ V A+ L
Sbjct: 93 MKVRKHINDLYEDLRDGHNLISLLEVLSGIKL------PREKGRMRFHRLQNVQIALDFL 146
Query: 193 LRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFR 227
+ + + D I N L L+ ++ +HF+
Sbjct: 147 KQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 181
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/113 (23%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 282 APDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLT 341
A ++ V KK+ +VNKHL K+ + +L DG L+ L+ +L +P +
Sbjct: 73 ADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMR 132
Query: 342 PESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
++ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 133 ----FHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 181
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/144 (27%), Positives = 63/144 (43%), Gaps = 12/144 (8%)
Query: 90 LVDVHPEDTQLEENEERTMI----DPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLE 145
L +V PE + +RT+ +P D + + K W+N L++ + + L
Sbjct: 145 LEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISDLY 204
Query: 146 EDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLRPRGWALRWS 203
EDL DG L LLE L+G L E G+ + KLQ V A+ L + +
Sbjct: 205 EDLRDGHNLISLLEVLSGDSL------PREKGRMRFHKLQNVQIALDYLRHRQVKLVNIR 258
Query: 204 VDSIHGKNLVAILHLLVSLAMHFR 227
D I N L L+ ++ +HF+
Sbjct: 259 NDDIADGNPKLTLGLIWTIILHFQ 282
Score = 38.1 bits (87), Expect = 0.014
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 288 VVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQ 347
V KK+ +VNKHL K +++L DG L+ L+ +L +P +
Sbjct: 180 VQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FH 235
Query: 348 KVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
K+ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 236 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 282
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/144 (27%), Positives = 63/144 (43%), Gaps = 12/144 (8%)
Query: 90 LVDVHPEDTQLEENEERTMI----DPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLE 145
L +V PE + +RT+ +P D + + K W+N L++ + + L
Sbjct: 141 LEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTSTKWVNKHLIKAQRHISDLY 200
Query: 146 EDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLRPRGWALRWS 203
EDL DG L LLE L+G L E G+ + KLQ V A+ L + +
Sbjct: 201 EDLRDGHNLISLLEVLSGDSL------PREKGRMRFHKLQNVQIALDYLRHRQVKLVNIR 254
Query: 204 VDSIHGKNLVAILHLLVSLAMHFR 227
D I N L L+ ++ +HF+
Sbjct: 255 NDDIADGNPKLTLGLIWTIILHFQ 278
Score = 37.4 bits (85), Expect = 0.024
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 288 VVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQ 347
V KK+ +VNKHL K +++L DG L+ L+ +L +P +
Sbjct: 176 VQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR----FH 231
Query: 348 KVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
K+ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 232 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 278
>gi|188595687 gamma filamin isoform b [Homo sapiens]
Length = 2692
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 278 LFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHH 337
L + AP K + + + + N+HL + +T+L+ +DG+ L+ L+ +L +
Sbjct: 28 LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRM-YRK 85
Query: 338 FYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKY 393
F+ P K+ NVS A E + +K + +V+ +LK L +++ L Y
Sbjct: 86 FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
>gi|116805322 gamma filamin isoform a [Homo sapiens]
Length = 2725
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 278 LFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHH 337
L + AP K + + + + N+HL + +T+L+ +DG+ L+ L+ +L +
Sbjct: 28 LAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRM-YRK 85
Query: 338 FYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKY 393
F+ P K+ NVS A E + +K + +V+ +LK L +++ L Y
Sbjct: 86 FHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 278 LFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHH 337
L + AP K + + + + N+HL +N + L+T +DG+ L+ L+ +L +
Sbjct: 8 LAEDAPWK-KIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRM-YRK 65
Query: 338 FYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKY 393
++ P ++ NVS A E + +K + +V+ +LK L +++ L Y
Sbjct: 66 YHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHY 121
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 39.3 bits (90), Expect = 0.006
Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 11/138 (7%)
Query: 115 EDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQS 174
+D + K K WIN L++ R V L EDL DG L LLE L+G +
Sbjct: 30 KDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSG------DTLPR 83
Query: 175 EIGQKQ--KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRL 232
E G+ + +LQ V A+ L R + + D I N L L+ ++ +HF+
Sbjct: 84 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS--- 140
Query: 233 PEHVTVQVVVVRKREGLL 250
HVT + + +E LL
Sbjct: 141 DIHVTGESEDMSAKERLL 158
Score = 37.7 bits (86), Expect = 0.018
Identities = 26/119 (21%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 276 DTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPL 335
D L + ++ V KK+ ++N+HL K+ V +L DG L+ L+ +L +P
Sbjct: 24 DVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR 83
Query: 336 HHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
+ ++ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 84 EKGRMR----FHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ 138
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/114 (21%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 284 DKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPE 343
++ +V KK+ +VN HL +++ +T+L T DG L+ L+ +L +P P
Sbjct: 38 EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLP------KPT 91
Query: 344 SFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
++H NV A + + + + D+V+ + + TL +++ + +++
Sbjct: 92 KGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 145
Score = 36.2 bits (82), Expect = 0.053
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 6/87 (6%)
Query: 80 NAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERI 139
++I+ P+SPA P + E + + D +E + K K W+N L
Sbjct: 7 SSISGPLSPAYTGQVPYNYNQLEGRFKQLQD--EREAVQKKTFTK----WVNSHLARVSC 60
Query: 140 IVKQLEEDLYDGQVLQKLLEKLAGCKL 166
+ L DL DG++L KLLE L+G +L
Sbjct: 61 RITDLYTDLRDGRMLIKLLEVLSGERL 87
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 39.3 bits (90), Expect = 0.006
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Query: 280 DHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFY 339
D ++ V KK+ +VNKHL K +++L DG L+ L+ +L +P
Sbjct: 35 DEQDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGR 94
Query: 340 LTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
+ K+ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 95 MR----FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 145
Score = 36.2 bits (82), Expect = 0.053
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 114 KEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQ 173
++D + + K W+N L++ + + L EDL DG L LLE L+G L
Sbjct: 36 EQDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSL------P 89
Query: 174 SEIGQKQ--KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFR 227
E G+ + KLQ V A+ L + + D I N L L+ ++ +HF+
Sbjct: 90 REKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 145
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 38.9 bits (89), Expect = 0.008
Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 8/133 (6%)
Query: 262 TTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYL 321
T + M E+D L + AP K + + + + N+HL ++ + L+T +DG+ L
Sbjct: 23 TRDAEMPATEKD----LAEDAPWK-KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRL 77
Query: 322 VLLMGLLEDYFVPLHHFYLTPESFDQ-KVHNVSFAFELMLDGGLKKPKARPEDVVNLDLK 380
+ L+ +L +H + +F Q ++ NVS A E + +K + +V+ +LK
Sbjct: 78 IALLEVLSQ--KKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLK 135
Query: 381 STLRVLYNLFTKY 393
L +++ L Y
Sbjct: 136 LILGLIWTLILHY 148
Score = 28.9 bits (63), Expect = 8.5
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Query: 115 EDPKFKELVK-VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQ 173
ED +K++ + W N+ L + L+ DL DG L LLE L+ K++ + Q
Sbjct: 37 EDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH-RKHNQ 95
Query: 174 SEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHF 226
++ +L+ V A+ L R + +I NL IL L+ +L +H+
Sbjct: 96 RPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHY 148
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 38.9 bits (89), Expect = 0.008
Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 8/133 (6%)
Query: 262 TTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYL 321
T + M E+D L + AP K + + + + N+HL ++ + L+T +DG+ L
Sbjct: 23 TRDAEMPATEKD----LAEDAPWK-KIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRL 77
Query: 322 VLLMGLLEDYFVPLHHFYLTPESFDQ-KVHNVSFAFELMLDGGLKKPKARPEDVVNLDLK 380
+ L+ +L +H + +F Q ++ NVS A E + +K + +V+ +LK
Sbjct: 78 IALLEVLSQ--KKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLK 135
Query: 381 STLRVLYNLFTKY 393
L +++ L Y
Sbjct: 136 LILGLIWTLILHY 148
Score = 28.9 bits (63), Expect = 8.5
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Query: 115 EDPKFKELVK-VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQ 173
ED +K++ + W N+ L + L+ DL DG L LLE L+ K++ + Q
Sbjct: 37 EDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMH-RKHNQ 95
Query: 174 SEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHF 226
++ +L+ V A+ L R + +I NL IL L+ +L +H+
Sbjct: 96 RPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHY 148
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 38.9 bits (89), Expect = 0.008
Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 282 APDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLT 341
A ++ V KK+ +VNKHL K +++L DG L+ L+ +L +P +
Sbjct: 64 ADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMR 123
Query: 342 PESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYK 394
K+ NV A + + +K R +D+ + + K TL +++ + ++
Sbjct: 124 ----FHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ 172
Score = 35.8 bits (81), Expect = 0.070
Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 13/128 (10%)
Query: 107 TMIDPTSKE-----DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKL 161
+++DP + D + + K W+N L++ + + L EDL DG L LLE L
Sbjct: 51 SVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL 110
Query: 162 AGCKLNVAEVTQSEIGQKQ--KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLL 219
+G L E G+ + KLQ V A+ L + + D I N L L+
Sbjct: 111 SGDSL------PREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLI 164
Query: 220 VSLAMHFR 227
++ +HF+
Sbjct: 165 WTIILHFQ 172
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 38.5 bits (88), Expect = 0.011
Identities = 28/128 (21%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 270 FERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLE 329
FER L D ++ V KK+ +VN HL +++ +T+L DG L+ L+ +L
Sbjct: 40 FERSRIKALAD---EREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLS 96
Query: 330 DYFVPLHHFYLTPESFDQKVH---NVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVL 386
+P P ++H NV A + + + + D+V+ + + L ++
Sbjct: 97 GEMLP------KPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLI 150
Query: 387 YNLFTKYK 394
+ + +++
Sbjct: 151 WTIILRFQ 158
Score = 32.7 bits (73), Expect = 0.59
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 124 KVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQ 183
K W+N L + L +DL DG++L KLLE L+G L + I L+
Sbjct: 58 KTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRI---HCLE 114
Query: 184 TVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVV 243
V +A+ L R I N +L L+ ++ + F+ +Q +VV
Sbjct: 115 NVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQ----------IQDIVV 164
Query: 244 RKREG 248
+ +EG
Sbjct: 165 QTQEG 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,591,800
Number of Sequences: 37866
Number of extensions: 638345
Number of successful extensions: 2054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1959
Number of HSP's gapped (non-prelim): 128
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.