Guide to the Human Genome
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Search of human proteins with 51173873

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]
         (601 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]      1184   0.0  
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     65   1e-10
gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens]       65   1e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    63   7e-10
gi|194688135 high-mobility group box 2 [Homo sapiens]                  61   3e-09
gi|194688133 high-mobility group box 2 [Homo sapiens]                  61   3e-09
gi|11321591 high-mobility group box 2 [Homo sapiens]                   61   3e-09
gi|226246533 TOX high mobility group box family member 3 isoform...    59   1e-08
gi|226054295 TOX high mobility group box family member 3 isoform...    59   1e-08
gi|4504425 high-mobility group box 1 [Homo sapiens]                    58   3e-08
gi|149408144 TOX high mobility group box family member 2 isoform...    57   4e-08
gi|149408141 TOX high mobility group box family member 2 isoform...    57   4e-08
gi|14249636 TOX high mobility group box family member 2 isoform ...    57   4e-08
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]             57   5e-08
gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]            56   1e-07
gi|71143137 high-mobility group box 3 [Homo sapiens]                   55   1e-07
gi|7662322 thymus high mobility group box protein TOX [Homo sapi...    54   4e-07
gi|169184027 PREDICTED: similar to high mobility group box 3 [Ho...    54   5e-07
gi|113421073 PREDICTED: similar to high mobility group box 3 [Ho...    54   5e-07
gi|113420668 PREDICTED: similar to high mobility group box 3 [Ho...    54   5e-07
gi|169217198 PREDICTED: similar to hCG1644442 [Homo sapiens]           53   7e-07
gi|169216377 PREDICTED: similar to hCG1644442 [Homo sapiens]           53   7e-07
gi|169216609 PREDICTED: hypothetical protein LOC203510 [Homo sap...    53   7e-07
gi|41281917 polybromo 1 isoform 4 [Homo sapiens]                       52   1e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    52   2e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    52   2e-06
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ...    51   3e-06
gi|169212060 PREDICTED: high mobility group protein B3-like prot...    51   3e-06
gi|239745831 PREDICTED: high mobility group protein B3-like prot...    51   3e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  51   3e-06

>gi|51173873 high-mobility group protein 2-like 1 [Homo sapiens]
          Length = 601

 Score = 1184 bits (3062), Expect = 0.0
 Identities = 601/601 (100%), Positives = 601/601 (100%)

Query: 1   MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK 60
           MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK
Sbjct: 1   MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLK 60

Query: 61  DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL 120
           DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL
Sbjct: 61  DSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPL 120

Query: 121 AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE 180
           AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE
Sbjct: 121 AAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTE 180

Query: 181 TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE 240
           TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE
Sbjct: 181 TLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHE 240

Query: 241 LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG 300
           LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG
Sbjct: 241 LQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGG 300

Query: 301 ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS 360
           ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS
Sbjct: 301 ELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS 360

Query: 361 GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE 420
           GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE
Sbjct: 361 GPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKE 420

Query: 421 YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS 480
           YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS
Sbjct: 421 YRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKAS 480

Query: 481 SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH 540
           SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH
Sbjct: 481 SSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGH 540

Query: 541 RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG 600
           RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG
Sbjct: 541 RLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPG 600

Query: 601 L 601
           L
Sbjct: 601 L 601


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 2/117 (1%)

Query: 389 KKKKKEEKDKERERGEKPK--KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWK 446
           K +K  +K  E ++G+ P   K+ MSAY ++    R  I +DHPGI   +LSKK  E+WK
Sbjct: 527 KDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWK 586

Query: 447 QLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSP 503
            + ++ K  W +KA+  +    KA       +  SS+     K   V V   +K +P
Sbjct: 587 GMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVKVKMEKKSTP 643


>gi|7662274 epidermal Langerhans cell protein LCP1 [Homo sapiens]
          Length = 621

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 25/198 (12%)

Query: 340 SKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSE----------- 388
           S+    LGLS   +G  T+   PP   P    +  P P   LH DG  +           
Sbjct: 147 SELSSQLGLS---LGGGTIL--PPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTV 201

Query: 389 -----KKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAE 443
                KK+K  +K K+++  E   +K +SAY +F ++ +  I   +P   FGE+SK +A 
Sbjct: 202 VVEAGKKQKAPKKRKKKDPNEP--QKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVAS 259

Query: 444 VWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSP 503
           +W  L E+ K ++K+K +    K+   +A    +     + +++         S     P
Sbjct: 260 MWDSLGEEQKQVYKRKTE--AAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPP 317

Query: 504 PTTMLLPASPAKAPETEP 521
           P   + PASPA A    P
Sbjct: 318 PMATVDPASPAPASIEPP 335


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 99/457 (21%), Positives = 180/457 (39%), Gaps = 67/457 (14%)

Query: 96  KKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGS 155
           KK+K  S  ST   +DL  A+ + +       ++  +KS G     + K++     +   
Sbjct: 3   KKQKNKSEDSTKDDIDL-DALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61

Query: 156 SGELPLEDGGSHKSKK---MKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQ 212
             EL LE  G    ++   +KP   N E  T ++      K     K K  S  D +S +
Sbjct: 62  LEELSLEAQGIKADRETVAVKPTENNEEEFTSKD------KKKKGQKGKKQSFDDNDSEE 115

Query: 213 YPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARK-KHKSSSDAHSSPGPEGCGSDA 271
              + +  KK++K       G+     +   F K  +K K K+        G E    ++
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGS----DDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNS 171

Query: 272 SQFAESHSANLD----------LSGLEPILVESDSSSGGELEAGELVIDDSYR----EIK 317
            +  E    N            L   +       +  G  +E+G    D S++      K
Sbjct: 172 KKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231

Query: 318 KKKKSKKSKKKKDKEKHK----------------EKRHSKSKRSLGLSAVPVGEVTVTSG 361
           K +K ++ +KK+D+EK K                + +  +S+R      V   +VTV +G
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVK-SKVTVDTG 290

Query: 362 PPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEY 421
             P      A+      P    D +   KKKK++K K+ E+ EK K+K     +   K  
Sbjct: 291 VIP------ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM 344

Query: 422 RVTIV-----ADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAE----- 471
           +  +       +    +  E  K+L E+  +  E+++L  +++ +  Q ++ + E     
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404

Query: 472 ---ATTVKRKA-SSSEGSMKVKASSVGVLSPQKKSPP 504
               T  +R+A + +E ++K+   + GV  P K S P
Sbjct: 405 GKLLTKSQREARARAEATLKL-LQAQGVEVPSKDSLP 440



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 88/432 (20%), Positives = 162/432 (37%), Gaps = 83/432 (19%)

Query: 25  AAGRSQREKKRSYKDFLREEEEIAAQVR-----NSSKKKLKDSELYFLGTDTHKKKRKH- 78
           A G++Q+  K+   D   E+E+ + +++     NSS +   +S+ +       KK +K+ 
Sbjct: 150 AKGKAQKSNKKW--DGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207

Query: 79  --------SSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKT 130
                   + DD     I ++   + +KK+   +  D     L+ +        K   +T
Sbjct: 208 PGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE------KEELET 261

Query: 131 GEKSSGSSSHSESKKEHH--RKKVSGSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPD 188
           G+K       S+ K E    + KV+  +G +P  +                ET T  E D
Sbjct: 262 GKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEE-------------KAETPTAAEDD 308

Query: 189 --GLKMKLILSPKEKGSSSVDEESFQYPSQQ---------ATVKKSSKKSARDEQGALLL 237
             G K K     K+      ++E  + PS+          A +K+  ++  R+E+  +  
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368

Query: 238 GHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSS 297
             EL++  K   +  +   +               Q  +     L   G   +L +S   
Sbjct: 369 LEELEAKRKEEERLEQEKRERKK------------QKEKERKERLKKEG--KLLTKSQRE 414

Query: 298 SGGELEAGELVIDDSYREIKKKKK-SKKSKKKKDKEKHKEKRHSKSKR---SLGL-SAVP 352
           +    EA   ++     E+  K    KK    +DK++ K  +  +SK    S+ L +AV 
Sbjct: 415 ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVE 474

Query: 353 VGEVTVTSG---PPPSIPYAGAAAPPLPLP---GLHTDGHSEK----------KKKKEEK 396
           V E  V      PPP  P          L     + +D  +EK          K+  EE+
Sbjct: 475 VMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEE 534

Query: 397 DKERERGEKPKK 408
           ++E E  E+ ++
Sbjct: 535 EEEEEEEEEDEE 546



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 40/229 (17%), Positives = 91/229 (39%), Gaps = 14/229 (6%)

Query: 15  GDHTFEDIGLAAGRSQREKKRSYKDFL--REEEEIAAQVRNSSKKKLKDSELYFLGTDTH 72
           GD + E +    G+ + +K +   +     E+++ + +++  ++KK +  E      D  
Sbjct: 187 GDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE 246

Query: 73  KKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGE 132
           K K +   +     ++ + +  Q K+K+S  +  +  +     + + +   S+   +T  
Sbjct: 247 KAKLRKLKEKE---ELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPT 303

Query: 133 KSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKK-----MKPLYVNTETLTLREP 187
            +   +   + KK+  +KK      E   + G S  + K     +  L    E     E 
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363

Query: 188 DGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALL 236
           + +K    L  K K    +++E  +   Q    K+  +K    ++G LL
Sbjct: 364 ERIKRLEELEAKRKEEERLEQEKRERKKQ----KEKERKERLKKEGKLL 408


>gi|194688135 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 1/87 (1%)

Query: 398 KERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWK 457
           K +++     K+  SA+ +FC E+R  I ++HPG+  G+ +KKL E+W +   KDK  ++
Sbjct: 86  KGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYE 145

Query: 458 QKAQYLQHKQNKAEATTVKRKASSSEG 484
           QKA  L+ K  K +    + K  S  G
Sbjct: 146 QKAAKLKEKYEK-DIAAYRAKGKSEAG 171



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 15/137 (10%)

Query: 405 KPKKKNMSAYQVFCKEYRVTIVADHP--GIDFGELSKKLAEVWKQLPEKDKLIWKQKAQY 462
           KP+ K MS+Y  F +  R      HP   ++F E SKK +E WK +  K+K  ++  A  
Sbjct: 8   KPRGK-MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMA-- 64

Query: 463 LQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPAS---PAKAPET 519
              K +KA      +     +G  K K           K PP+   L  S   P    E 
Sbjct: 65  ---KSDKARYDREMKNYVPPKGDKKGKKKDPNA----PKRPPSAFFLFCSEHRPKIKSEH 117

Query: 520 EPIDVAAHLQLLGESLS 536
             + +    + LGE  S
Sbjct: 118 PGLSIGDTAKKLGEMWS 134


>gi|194688133 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 1/87 (1%)

Query: 398 KERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWK 457
           K +++     K+  SA+ +FC E+R  I ++HPG+  G+ +KKL E+W +   KDK  ++
Sbjct: 86  KGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYE 145

Query: 458 QKAQYLQHKQNKAEATTVKRKASSSEG 484
           QKA  L+ K  K +    + K  S  G
Sbjct: 146 QKAAKLKEKYEK-DIAAYRAKGKSEAG 171



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 15/137 (10%)

Query: 405 KPKKKNMSAYQVFCKEYRVTIVADHP--GIDFGELSKKLAEVWKQLPEKDKLIWKQKAQY 462
           KP+ K MS+Y  F +  R      HP   ++F E SKK +E WK +  K+K  ++  A  
Sbjct: 8   KPRGK-MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMA-- 64

Query: 463 LQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPAS---PAKAPET 519
              K +KA      +     +G  K K           K PP+   L  S   P    E 
Sbjct: 65  ---KSDKARYDREMKNYVPPKGDKKGKKKDPNA----PKRPPSAFFLFCSEHRPKIKSEH 117

Query: 520 EPIDVAAHLQLLGESLS 536
             + +    + LGE  S
Sbjct: 118 PGLSIGDTAKKLGEMWS 134


>gi|11321591 high-mobility group box 2 [Homo sapiens]
          Length = 209

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 1/87 (1%)

Query: 398 KERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWK 457
           K +++     K+  SA+ +FC E+R  I ++HPG+  G+ +KKL E+W +   KDK  ++
Sbjct: 86  KGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYE 145

Query: 458 QKAQYLQHKQNKAEATTVKRKASSSEG 484
           QKA  L+ K  K +    + K  S  G
Sbjct: 146 QKAAKLKEKYEK-DIAAYRAKGKSEAG 171



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 15/137 (10%)

Query: 405 KPKKKNMSAYQVFCKEYRVTIVADHP--GIDFGELSKKLAEVWKQLPEKDKLIWKQKAQY 462
           KP+ K MS+Y  F +  R      HP   ++F E SKK +E WK +  K+K  ++  A  
Sbjct: 8   KPRGK-MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMA-- 64

Query: 463 LQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPAS---PAKAPET 519
              K +KA      +     +G  K K           K PP+   L  S   P    E 
Sbjct: 65  ---KSDKARYDREMKNYVPPKGDKKGKKKDPNA----PKRPPSAFFLFCSEHRPKIKSEH 117

Query: 520 EPIDVAAHLQLLGESLS 536
             + +    + LGE  S
Sbjct: 118 PGLSIGDTAKKLGEMWS 134


>gi|226246533 TOX high mobility group box family member 3 isoform 2
           [Homo sapiens]
          Length = 571

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 48/191 (25%), Positives = 87/191 (45%), Gaps = 28/191 (14%)

Query: 359 TSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPK----------- 407
           TS  PP    A  +A P P   ++ +   E  +   EK    + G+KPK           
Sbjct: 193 TSPSPP----ASKSATPSPSSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPN 248

Query: 408 --KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQH 465
             +K +SAY +F ++ +  I   +P   FGE+SK +A +W  L E+ K ++K+K +  + 
Sbjct: 249 EPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKK 308

Query: 466 KQNKA----EATTVKRKASSSEGSMKVKA-----SSVGVLSPQKKSPPTTM--LLPASPA 514
           +  KA     A+ V + A+ S  +  +++     +S  + S    + P +    + ASP 
Sbjct: 309 EYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQ 368

Query: 515 KAPETEPIDVA 525
              ++ P  +A
Sbjct: 369 TLQQSLPRSIA 379


>gi|226054295 TOX high mobility group box family member 3 isoform 1
           [Homo sapiens]
          Length = 576

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 48/191 (25%), Positives = 87/191 (45%), Gaps = 28/191 (14%)

Query: 359 TSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPK----------- 407
           TS  PP    A  +A P P   ++ +   E  +   EK    + G+KPK           
Sbjct: 198 TSPSPP----ASKSATPSPSSSINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPN 253

Query: 408 --KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQH 465
             +K +SAY +F ++ +  I   +P   FGE+SK +A +W  L E+ K ++K+K +  + 
Sbjct: 254 EPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKK 313

Query: 466 KQNKA----EATTVKRKASSSEGSMKVKA-----SSVGVLSPQKKSPPTTM--LLPASPA 514
           +  KA     A+ V + A+ S  +  +++     +S  + S    + P +    + ASP 
Sbjct: 314 EYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQ 373

Query: 515 KAPETEPIDVA 525
              ++ P  +A
Sbjct: 374 TLQQSLPRSIA 384


>gi|4504425 high-mobility group box 1 [Homo sapiens]
          Length = 215

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 26/72 (36%), Positives = 42/72 (58%)

Query: 398 KERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWK 457
           K++ +     K+  SA+ +FC EYR  I  +HPG+  G+++KKL E+W      DK  ++
Sbjct: 86  KKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYE 145

Query: 458 QKAQYLQHKQNK 469
           +KA  L+ K  K
Sbjct: 146 KKAAKLKEKYEK 157



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHP--GIDFGELSKKLAEVWKQLPEKDKLIWKQKAQ 461
           +KP+ K MS+Y  F +  R      HP   ++F E SKK +E WK +  K+K  ++  A+
Sbjct: 7   KKPRGK-MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAK 65

Query: 462 YLQHKQNKAEATTVKRKASSSE 483
             + +  +   T +  K  + +
Sbjct: 66  ADKARYEREMKTYIPPKGETKK 87


>gi|149408144 TOX high mobility group box family member 2 isoform a
           [Homo sapiens]
          Length = 506

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 14/130 (10%)

Query: 390 KKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLP 449
           KK K  K K+++   +P+K  +SAY +F ++ +  I   +P   FG++SK +A +W  L 
Sbjct: 230 KKAKNPKKKKKKDPNEPQKP-VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLG 288

Query: 450 EKDKLIWKQKAQYLQHKQNKAEA---TTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTT 506
           E+ K  +K+K +  + +  KA A    ++  K+S  +G  K            + +PP  
Sbjct: 289 EEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETK----------STQANPPAK 338

Query: 507 MLLPASPAKA 516
           ML P  P  A
Sbjct: 339 MLPPKQPMYA 348


>gi|149408141 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 14/130 (10%)

Query: 390 KKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLP 449
           KK K  K K+++   +P+K  +SAY +F ++ +  I   +P   FG++SK +A +W  L 
Sbjct: 188 KKAKNPKKKKKKDPNEPQKP-VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLG 246

Query: 450 EKDKLIWKQKAQYLQHKQNKAEA---TTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTT 506
           E+ K  +K+K +  + +  KA A    ++  K+S  +G  K            + +PP  
Sbjct: 247 EEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETK----------STQANPPAK 296

Query: 507 MLLPASPAKA 516
           ML P  P  A
Sbjct: 297 MLPPKQPMYA 306


>gi|14249636 TOX high mobility group box family member 2 isoform c
           [Homo sapiens]
          Length = 464

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 38/130 (29%), Positives = 65/130 (50%), Gaps = 14/130 (10%)

Query: 390 KKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLP 449
           KK K  K K+++   +P+K  +SAY +F ++ +  I   +P   FG++SK +A +W  L 
Sbjct: 188 KKAKNPKKKKKKDPNEPQKP-VSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLG 246

Query: 450 EKDKLIWKQKAQYLQHKQNKAEA---TTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTT 506
           E+ K  +K+K +  + +  KA A    ++  K+S  +G  K            + +PP  
Sbjct: 247 EEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETK----------STQANPPAK 296

Query: 507 MLLPASPAKA 516
           ML P  P  A
Sbjct: 297 MLPPKQPMYA 306


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 14/117 (11%)

Query: 386 HSEKKKK-----KEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKK 440
           H E++ K     K EK K+ +    PK+  + A+ +FC EYR  I  +HPG+   ++ KK
Sbjct: 744 HYEREMKTYIPPKGEKKKKFKDPNAPKRPPL-AFFLFCSEYRPKIKGEHPGLSIDDVVKK 802

Query: 441 LAEVWKQLPEKDKLIWKQKAQYLQHK--------QNKAEATTVKRKASSSEGSMKVK 489
           LA +W      DK  +++KA  L+ K        + K +  + K++   +E S K K
Sbjct: 803 LAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSKKKK 859


>gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]
          Length = 211

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 12/119 (10%)

Query: 386 HSEKKKKK----EEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKL 441
           H E++ K     + + K++ +     K+  SA+ +FC EY   I  +HPG+  G+++KKL
Sbjct: 70  HYERQMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYHPKIKGEHPGLSIGDVAKKL 129

Query: 442 AEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQK 500
            E+W      DK   ++KA  L+ K  K  A      A  ++G  K +A+  GV+  +K
Sbjct: 130 GEMWNNTAADDKQPGEKKAAKLKEKYEKDIA------AYQAKG--KPEAAKKGVVKAEK 180



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 3/52 (5%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHP--GIDFGELSKKLAEVWKQLPEKDK 453
           +KP+ K MS+Y  F +  R      H    ++F E S K +E WK +  K+K
Sbjct: 7   KKPRGK-MSSYAFFVQTCREEHKKKHSDASVNFSEFSNKCSERWKTMSAKEK 57


>gi|71143137 high-mobility group box 3 [Homo sapiens]
          Length = 200

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 7/108 (6%)

Query: 393 KEEKDKERERGEKPKK------KNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWK 446
           +E KD    +G K KK      +  S + +FC E+R  I + +PGI  G+++KKL E+W 
Sbjct: 73  REMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWN 132

Query: 447 QLPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKVKASSV 493
            L + +K  +  KA  L+ K  K  A    K K   ++G  KV    V
Sbjct: 133 NLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKV 180



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 17/135 (12%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPGI--DFGELSKKLAEVWKQLPEKDKLIWKQKAQ 461
           +KPK K MSAY  F +  R      +P +  +F E SKK +E WK +  K+K  + + A 
Sbjct: 7   KKPKGK-MSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMA- 64

Query: 462 YLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASP--AKAPET 519
               K +K       +    ++G  K K  +        K PP+   L  S    K   T
Sbjct: 65  ----KADKVRYDREMKDYGPAKGGKKKKDPNA------PKRPPSGFFLFCSEFRPKIKST 114

Query: 520 EP-IDVAAHLQLLGE 533
            P I +    + LGE
Sbjct: 115 NPGISIGDVAKKLGE 129


>gi|7662322 thymus high mobility group box protein TOX [Homo
           sapiens]
          Length = 526

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 14/109 (12%)

Query: 367 PYAGAAAPPLPLPGLHTD-GHSEKKKKKEEKDKERERGEKPK-------------KKNMS 412
           P    +A P P   +H D G    K    EK    + G+KPK             +K +S
Sbjct: 207 PPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKKKKKKDPNEPQKPVS 266

Query: 413 AYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQ 461
           AY +F ++ +  I   +P   FGE+SK +A +W  L E+ K ++K+K +
Sbjct: 267 AYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTE 315


>gi|169184027 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 5/82 (6%)

Query: 393 KEEKDKERERGEKPKKKNM-----SAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD    +G K K  N      S + +FC E+R  I + +PGI  G+++KKL E+W  
Sbjct: 73  REMKDYGPAKGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNK 469
           L + +K  +  KA  L+ K  K
Sbjct: 133 LNDSEKQPYVTKAAKLKEKYEK 154



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 11/64 (17%)

Query: 404 EKPKKKNMSAY----QVFCKEYRVTIVADHPGI--DFGELSKKLAEVWKQLPEKDKLIWK 457
           +KP+ K MSAY    Q  CKE++      +P +  +F E SKK +  WK +  K+K  + 
Sbjct: 7   KKPQGK-MSAYAFSVQTCCKEHK----KKNPEVLVNFAEFSKKCSGRWKTMSSKEKFKFG 61

Query: 458 QKAQ 461
           + A+
Sbjct: 62  EMAK 65


>gi|113421073 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 5/82 (6%)

Query: 393 KEEKDKERERGEKPKKKNM-----SAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD    +G K K  N      S + +FC E+R  I + +PGI  G+++KKL E+W  
Sbjct: 73  REMKDYGPAKGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNK 469
           L + +K  +  KA  L+ K  K
Sbjct: 133 LNDSEKQPYVTKAAKLKEKYEK 154



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 7/62 (11%)

Query: 404 EKPKKKNMSAY----QVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQK 459
           +KP+ K MSAY    Q  CKE++         ++F E SKK +  WK +  K+K  + + 
Sbjct: 7   KKPQGK-MSAYAFSVQTCCKEHKKK--NPEVPVNFAEFSKKCSGRWKTMSSKEKFKFGEM 63

Query: 460 AQ 461
           A+
Sbjct: 64  AK 65


>gi|113420668 PREDICTED: similar to high mobility group box 3 [Homo
           sapiens]
          Length = 208

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 5/82 (6%)

Query: 393 KEEKDKERERGEKPKKKNM-----SAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD    +G K K  N      S + +FC E+R  I + +PGI  G+++KKL E+W  
Sbjct: 73  REMKDYGPAKGGKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNK 469
           L + +K  +  KA  L+ K  K
Sbjct: 133 LNDSEKQPYVTKAAKLKEKYEK 154



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 7/62 (11%)

Query: 404 EKPKKKNMSAY----QVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQK 459
           +KP+ K MSAY    Q  CKE++         ++F E SKK +  WK +  K+K  + + 
Sbjct: 7   KKPQGK-MSAYAFSVQTCCKEHKKK--NPEVPVNFAEFSKKCSGRWKTMSSKEKFKFGEM 63

Query: 460 AQ 461
           A+
Sbjct: 64  AK 65


>gi|169217198 PREDICTED: similar to hCG1644442 [Homo sapiens]
          Length = 201

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 6/102 (5%)

Query: 393 KEEKDKERERGEKPK-----KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD     G K K     K+ +S + +FC E+   I + +PGI  G+++KKL E+W  
Sbjct: 73  QEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGISIGDMAKKLGEMWIN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKV 488
             +++K  +  KA  L+ K  K  A    K K  S++G  K+
Sbjct: 133 YSDREKQPYITKAADLKEKYEKDVADYKSKGKFDSAKGPTKI 174



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 21/112 (18%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPGI--DFGELSKKLAEVWKQLPEKDKLIWKQ--- 458
           +KPK K MSAY  F +  R      +P +  +F E SKK +E  K +  K+K  + +   
Sbjct: 7   KKPKGK-MSAYAFFAQTCREEHKKKNPEVPVNFVEFSKKCSEKRKTMSGKEKTKFDEMAK 65

Query: 459 --KAQYLQHKQN--------KAEATTVKRKASS-----SEGSMKVKASSVGV 495
             K  Y Q  ++        K +   +KR  S      SE   K+K+++ G+
Sbjct: 66  VDKVHYDQEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGI 117


>gi|169216377 PREDICTED: similar to hCG1644442 [Homo sapiens]
          Length = 201

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 6/102 (5%)

Query: 393 KEEKDKERERGEKPK-----KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD     G K K     K+ +S + +FC E+   I + +PGI  G+++KKL E+W  
Sbjct: 73  QEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGISIGDMAKKLGEMWIN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKV 488
             +++K  +  KA  L+ K  K  A    K K  S++G  K+
Sbjct: 133 YSDREKQPYITKAADLKEKYEKDVADYKSKGKFDSAKGPTKI 174



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 21/112 (18%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPGI--DFGELSKKLAEVWKQLPEKDKLIWKQ--- 458
           +KPK K MSAY  F +  R      +P +  +F E SKK +E  K +  K+K  + +   
Sbjct: 7   KKPKGK-MSAYAFFAQTCREEHKKKNPEVPVNFVEFSKKCSEKRKTMSGKEKTKFDEMAK 65

Query: 459 --KAQYLQHKQN--------KAEATTVKRKASS-----SEGSMKVKASSVGV 495
             K  Y Q  ++        K +   +KR  S      SE   K+K+++ G+
Sbjct: 66  VDKVHYDQEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGI 117


>gi|169216609 PREDICTED: hypothetical protein LOC203510 [Homo
           sapiens]
          Length = 201

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 6/102 (5%)

Query: 393 KEEKDKERERGEKPK-----KKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD     G K K     K+ +S + +FC E+   I + +PGI  G+++KKL E+W  
Sbjct: 73  QEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGISIGDMAKKLGEMWIN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKV 488
             +++K  +  KA  L+ K  K  A    K K  S++G  K+
Sbjct: 133 YSDREKQPYITKAADLKEKYEKDVADYKSKGKFDSAKGPTKI 174



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 21/112 (18%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPGI--DFGELSKKLAEVWKQLPEKDKLIWKQ--- 458
           +KPK K MSAY  F +  R      +P +  +F E SKK +E  K +  K+K  + +   
Sbjct: 7   KKPKGK-MSAYAFFAQTCREEHKKKNPEVPVNFVEFSKKCSEKRKTMSGKEKTKFDEMAK 65

Query: 459 --KAQYLQHKQN--------KAEATTVKRKASS-----SEGSMKVKASSVGV 495
             K  Y Q  ++        K +   +KR  S      SE   K+K+++ G+
Sbjct: 66  VDKVHYDQEMKDNGPVEGGKKKDPNALKRPLSGFFLFCSEFHPKIKSTNPGI 117


>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
          Length = 1582

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 60/194 (30%), Positives = 80/194 (41%), Gaps = 26/194 (13%)

Query: 375  PLPLPGLHTDGHSE---------KKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTI 425
            P  LP L T   SE         +   K  K   ++ G K +K NMS Y +F  E R  I
Sbjct: 1339 PPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSK-RKINMSGYILFSSEMRAVI 1397

Query: 426  VADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGS 485
             A HP   FGELS+ +   W+ L         +KA+Y +   N+  A  V   A      
Sbjct: 1398 KAQHPDYSFGELSRLVGTEWRNLET------AKKAEY-EGVMNQGVAPMVGTPAPGG--- 1447

Query: 486  MKVKASSVGVLSP--QKKSPPTTMLLPASPAKAPE-TEPIDVAAHLQLLGESLSLIGHRL 542
                   VGVL P  Q+  PP     PA P    + T P+ VA   +   + L      L
Sbjct: 1448 -SPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKT--QRLLHSEAYL 1504

Query: 543  QETEGMVAVSGSLS 556
            +  EG+ A S S+S
Sbjct: 1505 KYIEGLSAESNSIS 1518


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 87/404 (21%), Positives = 145/404 (35%), Gaps = 63/404 (15%)

Query: 29   SQREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLG------TDTHKKKRKHSSDD 82
            S + +K S  D L E+    +  ++S + +  D             T    KK  + + +
Sbjct: 1388 STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTRE 1447

Query: 83   YYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSE 142
            Y        ++   ++K S  ++ D+A         P      P K TG+    +SS S 
Sbjct: 1448 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKN---KPREERDLPKKGTGDSKKSNSSPSR 1504

Query: 143  SKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNT-ETLTLREPDGLKMKLILSP--- 198
             +K H  K    +  + P E+  S      K    +  E    +E  G K+  IL+P   
Sbjct: 1505 DRKPHDHKATYDT--KRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET 1562

Query: 199  ---KEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLG--HELQSFLKTARKKHK 253
               KE+ +  +D+ + +   Q +   + S    R+   A      +E  S    + K+ +
Sbjct: 1563 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1622

Query: 254  SSS-------DAHSSPGPEGCGSDAS-QFAESHSANLDLSGLEPILVESDSSSGGELEAG 305
            SS        D       E   + A  Q   S + +     + P    S S S     + 
Sbjct: 1623 SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1682

Query: 306  ELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPS 365
                 +S    KKKKK +K K KK K+  K K+H+ ++  L  S                
Sbjct: 1683 SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS---------------- 1726

Query: 366  IPYAGAAAPPLPLPGLHTDGHSEKKKK-KEEKDKERERGEKPKK 408
                                H  KKKK K+ KDKE+E+ +  +K
Sbjct: 1727 ------------------QKHKHKKKKSKKNKDKEKEKEKDDQK 1752



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 93/418 (22%), Positives = 157/418 (37%), Gaps = 67/418 (16%)

Query: 30   QREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKR------KHSSDDY 83
            Q+  K    + ++ E + +    +S K K KD +   L  +  +K++      K S+ D 
Sbjct: 1340 QKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDR 1399

Query: 84   Y--YGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTG--EKSSGSSS 139
                G+  SL  S K+ + S    +  A       +S         KKT    +   SS 
Sbjct: 1400 LNEQGNFKSLSQSSKEARTSDKHDSTRA-------SSNKDFTPNRDKKTDYDTREYSSSK 1452

Query: 140  HSESKKEHHRKKVSGSSG-------------ELPLEDGGSHKSKKMKPLYVNTETLTLRE 186
              + K E  R+K S S               E  L   G+  SKK      N+     R+
Sbjct: 1453 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKS-----NSSPSRDRK 1507

Query: 187  PDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLK 246
            P   K         + + SVD+   +   +     +++K+S+ ++   +L   E Q    
Sbjct: 1508 PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQ---- 1563

Query: 247  TARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGE 306
               K+  +     S+  P+   S +S+ +   +   D +  EP   ESDS S        
Sbjct: 1564 -VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESN------- 1615

Query: 307  LVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAV-PVGEVTVTSGPPPS 365
                     +  K++       KD    K+K   K+K SL  +AV  VG     S   PS
Sbjct: 1616 ---------VSVKEEESSGNISKDL---KDKIVEKAKESLDTAAVVQVGISRNQSHSSPS 1663

Query: 366  IPYAGAAAPPLPLPGLHTDG-------HSEKKKKKEEKDKERERGEKPKKKNMSAYQV 416
            +  + + +P       H+          S+KKKKK+EK K ++  +  K K  +  +V
Sbjct: 1664 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV 1721



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 45/219 (20%), Positives = 79/219 (36%), Gaps = 31/219 (14%)

Query: 119  PLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVN 178
            P A G K  +K    +     +     +  ++KV G     P  +    K+K+  P   N
Sbjct: 978  PKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN 1037

Query: 179  TETLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLG 238
            T++ +  + D    K+  +P++  S S  E     P ++  VKK   K  + E       
Sbjct: 1038 TKSSSSSQKD---EKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSE------- 1087

Query: 239  HELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSS 298
                   K   K+ K+      +   +  G    +  E    + D         ES S  
Sbjct: 1088 -------KLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDF--------ESSSMK 1132

Query: 299  GGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEK 337
              +LE  E+V      +   K+K +   +K D+   K+K
Sbjct: 1133 ISKLEVTEIV------KPSPKRKMEPDTEKMDRTPEKDK 1165



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 89/379 (23%), Positives = 136/379 (35%), Gaps = 94/379 (24%)

Query: 164  GGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKS 223
            G SH+S+ +   Y   E L+ R  DG   K     KEK S +   +       +    K 
Sbjct: 852  GQSHRSRNIGSNY--PEKLSAR--DGHNQKDNTKSKEKESENAPGDG------KGNKHKK 901

Query: 224  SKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLD 283
             +K  + E+    L  EL   L+T+RK  + +       G E   +D+     S      
Sbjct: 902  HRKRRKGEESEGFLNPEL---LETSRKSREPT-------GVEENKTDSLFVLPSRDDATP 951

Query: 284  LSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSK 343
            +   EP+  ES                     I  K  S+K K+++DK K K     K+K
Sbjct: 952  VRD-EPMDAES---------------------ITFKSVSEKDKRERDKPKAKG---DKTK 986

Query: 344  RSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERG 403
            R    SAV   E  V                P   P    DG  E+  + E   K+ +  
Sbjct: 987  RKNDGSAVSKKENIVK---------------PAKGPQEKVDGERERSPRSEPPIKKAKE- 1030

Query: 404  EKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQ----- 458
            E PK  N  +     K+ ++T      G      SK   E  +  P K++ + K      
Sbjct: 1031 ETPKTDNTKSSSSSQKDEKIT------GTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDV 1084

Query: 459  KAQYLQHKQNKAEATTVKRKASSSEG-------------------SMKVKASSVGVL--- 496
            K++ L  K+ KA+    K K   ++G                   SMK+    V  +   
Sbjct: 1085 KSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKP 1144

Query: 497  SPQKKSPPTTMLLPASPAK 515
            SP++K  P T  +  +P K
Sbjct: 1145 SPKRKMEPDTEKMDRTPEK 1163


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 87/404 (21%), Positives = 145/404 (35%), Gaps = 63/404 (15%)

Query: 29   SQREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLG------TDTHKKKRKHSSDD 82
            S + +K S  D L E+    +  ++S + +  D             T    KK  + + +
Sbjct: 1422 STQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTRE 1481

Query: 83   YYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSE 142
            Y        ++   ++K S  ++ D+A         P      P K TG+    +SS S 
Sbjct: 1482 YSSSKRRDEKNELTRRKDSPSRNKDSASGQKN---KPREERDLPKKGTGDSKKSNSSPSR 1538

Query: 143  SKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNT-ETLTLREPDGLKMKLILSP--- 198
             +K H  K    +  + P E+  S      K    +  E    +E  G K+  IL+P   
Sbjct: 1539 DRKPHDHKATYDT--KRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET 1596

Query: 199  ---KEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLG--HELQSFLKTARKKHK 253
               KE+ +  +D+ + +   Q +   + S    R+   A      +E  S    + K+ +
Sbjct: 1597 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1656

Query: 254  SSS-------DAHSSPGPEGCGSDAS-QFAESHSANLDLSGLEPILVESDSSSGGELEAG 305
            SS        D       E   + A  Q   S + +     + P    S S S     + 
Sbjct: 1657 SSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1716

Query: 306  ELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPS 365
                 +S    KKKKK +K K KK K+  K K+H+ ++  L  S                
Sbjct: 1717 SASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS---------------- 1760

Query: 366  IPYAGAAAPPLPLPGLHTDGHSEKKKK-KEEKDKERERGEKPKK 408
                                H  KKKK K+ KDKE+E+ +  +K
Sbjct: 1761 ------------------QKHKHKKKKSKKNKDKEKEKEKDDQK 1786



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 93/418 (22%), Positives = 157/418 (37%), Gaps = 67/418 (16%)

Query: 30   QREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKR------KHSSDDY 83
            Q+  K    + ++ E + +    +S K K KD +   L  +  +K++      K S+ D 
Sbjct: 1374 QKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDR 1433

Query: 84   Y--YGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTG--EKSSGSSS 139
                G+  SL  S K+ + S    +  A       +S         KKT    +   SS 
Sbjct: 1434 LNEQGNFKSLSQSSKEARTSDKHDSTRA-------SSNKDFTPNRDKKTDYDTREYSSSK 1486

Query: 140  HSESKKEHHRKKVSGSSG-------------ELPLEDGGSHKSKKMKPLYVNTETLTLRE 186
              + K E  R+K S S               E  L   G+  SKK      N+     R+
Sbjct: 1487 RRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKS-----NSSPSRDRK 1541

Query: 187  PDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLK 246
            P   K         + + SVD+   +   +     +++K+S+ ++   +L   E Q    
Sbjct: 1542 PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQ---- 1597

Query: 247  TARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGE 306
               K+  +     S+  P+   S +S+ +   +   D +  EP   ESDS S        
Sbjct: 1598 -VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESN------- 1649

Query: 307  LVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAV-PVGEVTVTSGPPPS 365
                     +  K++       KD    K+K   K+K SL  +AV  VG     S   PS
Sbjct: 1650 ---------VSVKEEESSGNISKDL---KDKIVEKAKESLDTAAVVQVGISRNQSHSSPS 1697

Query: 366  IPYAGAAAPPLPLPGLHTDG-------HSEKKKKKEEKDKERERGEKPKKKNMSAYQV 416
            +  + + +P       H+          S+KKKKK+EK K ++  +  K K  +  +V
Sbjct: 1698 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV 1755



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 45/219 (20%), Positives = 79/219 (36%), Gaps = 31/219 (14%)

Query: 119  PLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVN 178
            P A G K  +K    +     +     +  ++KV G     P  +    K+K+  P   N
Sbjct: 1012 PKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN 1071

Query: 179  TETLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLG 238
            T++ +  + D    K+  +P++  S S  E     P ++  VKK   K  + E       
Sbjct: 1072 TKSSSSSQKD---EKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSE------- 1121

Query: 239  HELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSS 298
                   K   K+ K+      +   +  G    +  E    + D         ES S  
Sbjct: 1122 -------KLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDF--------ESSSMK 1166

Query: 299  GGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEK 337
              +LE  E+V      +   K+K +   +K D+   K+K
Sbjct: 1167 ISKLEVTEIV------KPSPKRKMEPDTEKMDRTPEKDK 1199



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 89/379 (23%), Positives = 136/379 (35%), Gaps = 94/379 (24%)

Query: 164  GGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKS 223
            G SH+S+ +   Y   E L+ R  DG   K     KEK S +   +       +    K 
Sbjct: 886  GQSHRSRNIGSNY--PEKLSAR--DGHNQKDNTKSKEKESENAPGDG------KGNKHKK 935

Query: 224  SKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLD 283
             +K  + E+    L  EL   L+T+RK  + +       G E   +D+     S      
Sbjct: 936  HRKRRKGEESEGFLNPEL---LETSRKSREPT-------GVEENKTDSLFVLPSRDDATP 985

Query: 284  LSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSK 343
            +   EP+  ES                     I  K  S+K K+++DK K K     K+K
Sbjct: 986  VRD-EPMDAES---------------------ITFKSVSEKDKRERDKPKAKG---DKTK 1020

Query: 344  RSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERG 403
            R    SAV   E  V                P   P    DG  E+  + E   K+ +  
Sbjct: 1021 RKNDGSAVSKKENIVK---------------PAKGPQEKVDGERERSPRSEPPIKKAKE- 1064

Query: 404  EKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQ----- 458
            E PK  N  +     K+ ++T      G      SK   E  +  P K++ + K      
Sbjct: 1065 ETPKTDNTKSSSSSQKDEKIT------GTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDV 1118

Query: 459  KAQYLQHKQNKAEATTVKRKASSSEG-------------------SMKVKASSVGVL--- 496
            K++ L  K+ KA+    K K   ++G                   SMK+    V  +   
Sbjct: 1119 KSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKP 1178

Query: 497  SPQKKSPPTTMLLPASPAK 515
            SP++K  P T  +  +P K
Sbjct: 1179 SPKRKMEPDTEKMDRTPEK 1197


>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 1112

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 84/396 (21%), Positives = 148/396 (37%), Gaps = 83/396 (20%)

Query: 187 PDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLK 246
           P+GL +   ++     S S DE       ++   +   + S  DE+       EL    +
Sbjct: 527 PEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEE-------ELAR-RR 578

Query: 247 TARKKHKSSSDAH--SSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEA 304
            ARK+ ++++  +  SSP P+    D           +DLS   P+ V      G  +  
Sbjct: 579 EARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLS--VPLKVP-----GLPMSD 631

Query: 305 GELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTS---- 360
             + +++  R  +K +K K+ KK+K+KEK  ++RHS           P  +V + +    
Sbjct: 632 QYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMP 691

Query: 361 ---------GPPPSIPYAG-------------------------AAAPPLPLPGLHTDGH 386
                       P+ PY                           + +P   +P +     
Sbjct: 692 ENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSK 751

Query: 387 SEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYR-----VTIVADHPGIDFGELSKKL 441
             KKK+K+ K+KER++ +K +K+  +    F              A  P  D  E +K  
Sbjct: 752 KPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECEDAKTE 811

Query: 442 AEVWKQLPE-KDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQK 500
           A+  +   E +D+     K +  +H++ K E T  K+K+                    K
Sbjct: 812 AQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKS--------------------K 851

Query: 501 KSPPTTMLLPASPAK--APETEPIDVAAHLQLLGES 534
           K PP +      P +  APE E +   +   LL E+
Sbjct: 852 KQPPGSEEAAGEPVQNGAPEEEQLPPESSYSLLAEN 887



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 67/360 (18%), Positives = 124/360 (34%), Gaps = 44/360 (12%)

Query: 25  AAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYY 84
           A    + +++  ++    +EEE+A   R  ++K+ + +  +++ +    +KR   +    
Sbjct: 552 AVFHEEEQRRPKHRPSEADEEELAR--RREARKQEQANNPFYIKSSPSPQKRYQDTPGVE 609

Query: 85  YGDISSLESSQKKKKKSSPQSTD-TAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSES 143
           +  +  ++ S   K    P S     ++  +     L    +  K+  ++  G   HS  
Sbjct: 610 HIPVVQIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSL 669

Query: 144 KKEHHR-----KKVSGSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSP 198
             E        ++V   + E+P     S +  K          + L +P     KL +  
Sbjct: 670 PTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQK 729

Query: 199 KEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDA 258
                +S   E    P  +   KK  KK  + ++       E     K  ++K     D 
Sbjct: 730 HRNTETSKSPEK-DVPMVEKKSKKPKKKEKKHKE------KERDKEKKKEKEKKAEDLDF 782

Query: 259 HSS----PGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYR 314
             S    P P    +      E   A  +  G      E D + G           D  +
Sbjct: 783 WLSTTPPPAPAPAPAPVPSTDECEDAKTEAQG------EEDDAEG----------QDQDK 826

Query: 315 EIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGP-----PPSIPYA 369
           +  K KK K  K+K+++ K K+    KSK+    S    GE      P     PP   Y+
Sbjct: 827 KSPKPKKKKHRKEKEERTKGKK----KSKKQPPGSEEAAGEPVQNGAPEEEQLPPESSYS 882


>gi|169212060 PREDICTED: high mobility group protein B3-like
           protein-like [Homo sapiens]
          Length = 207

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 393 KEEKDKERERGEKPKKKNM-----SAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD    +G K K  N      S + +FC E+     + +PGI  G+++KKL E+WK 
Sbjct: 73  QEIKDYGPAKGGKKKDPNAPKRPPSGFFLFCSEFCPKSKSTNPGIPIGDVAKKLGEMWKN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKVKASSV 493
           L + +K  +  +A  L+ K  K  A    K K+  ++G  KV    V
Sbjct: 133 LNDSEKQPYITQAAKLKEKYEKDVAVYKSKGKSDGAKGPAKVAQKKV 179



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPG--IDFGELSKKLAEVWKQLPEKDK-----LIW 456
           +KPK K MSAY  F +  R      +P   I+F E SKK +E WK + +K+K     L  
Sbjct: 7   KKPKGK-MSAYAFFVQTCREEHKKKNPKVPINFAEFSKKCSERWKTMSKKEKSKFNELAK 65

Query: 457 KQKAQYLQHKQNKAEATTVKRK 478
             K  Y Q  ++   A   K+K
Sbjct: 66  ADKVHYDQEIKDYGPAKGGKKK 87


>gi|239745831 PREDICTED: high mobility group protein B3-like
           protein-like [Homo sapiens]
          Length = 207

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 393 KEEKDKERERGEKPKKKNM-----SAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQ 447
           +E KD    +G K K  N      S + +FC E+     + +PGI  G+++KKL E+WK 
Sbjct: 73  QEIKDYGPAKGGKKKDPNAPKRPPSGFFLFCSEFCPKSKSTNPGIPIGDVAKKLGEMWKN 132

Query: 448 LPEKDKLIWKQKAQYLQHKQNKAEAT-TVKRKASSSEGSMKVKASSV 493
           L + +K  +  +A  L+ K  K  A    K K+  ++G  KV    V
Sbjct: 133 LNDSEKQPYITQAAKLKEKYEKDVAVYKSKGKSDGAKGPAKVAQKKV 179



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 404 EKPKKKNMSAYQVFCKEYRVTIVADHPG--IDFGELSKKLAEVWKQLPEKDK-----LIW 456
           +KPK K MSAY  F +  R      +P   I+F E SKK +E WK + +K+K     L  
Sbjct: 7   KKPKGK-MSAYAFFVQTCREEHKKKNPKVPINFAEFSKKCSERWKTMSKKEKSKFNELAK 65

Query: 457 KQKAQYLQHKQNKAEATTVKRK 478
             K  Y Q  ++   A   K+K
Sbjct: 66  ADKVHYDQEIKDYGPAKGGKKK 87


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 46/173 (26%), Positives = 71/173 (41%), Gaps = 39/173 (22%)

Query: 246 KTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAG 305
           K  +K+HKSSS + SS       SD+   ++S                SDS S  E    
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDS----------------SDSESATE---- 224

Query: 306 ELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRS--LGLSAVPVGEVTVTSGPP 363
                +  ++ KKK +    K KK+K+K K+ + S S  S    L A P   V     PP
Sbjct: 225 -----EKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279

Query: 364 -PSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQ 415
            P   +    +PP              +K+++ +++ERER   P     ++YQ
Sbjct: 280 IPENRFLMRKSPP-----------KADEKERKNRERERERECNPPNSQPASYQ 321



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 74/406 (18%), Positives = 145/406 (35%), Gaps = 64/406 (15%)

Query: 89  SSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSS---------GSSS 139
           S ++  +KK+ KSS  S+ ++ D   +  S  ++ S  S+   E+ S          S  
Sbjct: 181 SKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRK 240

Query: 140 HSESKKEHHRKKVSGSS----GELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLI 195
           H + KK+  + K S SS      L  +   + + +++ P+  N   +    P        
Sbjct: 241 HKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA------ 294

Query: 196 LSPKEKGSSSVDEESFQYP--SQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHK 253
              KE+ +   + E    P  SQ A+ +   ++      G  + G   + +   +R + +
Sbjct: 295 -DEKERKNRERERERECNPPNSQPASYQ---RRLLVTRSGRKIKGRGPRRYRTPSRSRSR 350

Query: 254 SSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSY 313
                  +P         +Q     S    + G +  L E   +    +   E  I D +
Sbjct: 351 DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITD-H 409

Query: 314 REIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAA 373
           R + +    K  K+KK K+     +    +R+                            
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRN---------------------------- 441

Query: 374 PPLPLPGLHTDGHSEKKKKKEEKDKERERG-EKPKKKNMSAYQVFCKEYRVTIVADHPGI 432
                     D   + K KK  K K R +  EK K K   +     +E R+   +   G 
Sbjct: 442 -------SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMR--SRSKGR 492

Query: 433 DFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRK 478
           D   + +K  +   +  ++++   K+K++ L+ K N+ + +  K K
Sbjct: 493 DHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 11/131 (8%)

Query: 27  GRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYG 86
           GRS+ + +R  +   R  E   +Q RN  K + ++S+      ++  +KR +S    +  
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNS 673

Query: 87  DISSLE------SSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSS- 139
             +S E       S   K K S Q  +    +LK         S   +K  +KS G  + 
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS--VEKENQKSKGQEND 731

Query: 140 --HSESKKEHH 148
             H ++KK  H
Sbjct: 732 HVHEKNKKFDH 742



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 457 KQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQK--KSPPTTMLLPASPA 514
           K +    +HK+ K +    K+ ASS   +  ++A     + P++    P    L+  SP 
Sbjct: 233 KHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPP 292

Query: 515 KAPETE 520
           KA E E
Sbjct: 293 KADEKE 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.124    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,389,176
Number of Sequences: 37866
Number of extensions: 1305924
Number of successful extensions: 14312
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 472
Number of HSP's that attempted gapping in prelim test: 8830
Number of HSP's gapped (non-prelim): 3913
length of query: 601
length of database: 18,247,518
effective HSP length: 108
effective length of query: 493
effective length of database: 14,157,990
effective search space: 6979889070
effective search space used: 6979889070
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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