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Search of human proteins with 51173722
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51173722 bromodomain and PHD finger-containing protein 1
isoform 2 [Homo sapiens]
(1214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 2494 0.0
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 2487 0.0
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 1125 0.0
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 1108 0.0
gi|117190334 PHD finger protein 16 [Homo sapiens] 224 5e-58
gi|7662006 PHD finger protein 16 [Homo sapiens] 224 5e-58
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 218 3e-56
gi|40556370 PHD finger protein 15 [Homo sapiens] 206 1e-52
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 198 2e-50
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 172 1e-42
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 172 1e-42
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 172 2e-42
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 130 1e-29
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 130 1e-29
gi|45504380 jumonji domain containing 2B [Homo sapiens] 126 1e-28
gi|98986459 jumonji domain containing 2A [Homo sapiens] 121 5e-27
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 114 4e-25
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 114 4e-25
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 91 9e-18
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 91 9e-18
gi|41350212 bromodomain containing 7 [Homo sapiens] 87 7e-17
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 75 5e-13
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 69 2e-11
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 67 8e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 66 2e-10
gi|164419758 bromodomain containing 2 [Homo sapiens] 65 5e-10
gi|4826806 bromodomain containing 2 [Homo sapiens] 65 5e-10
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 64 1e-09
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 63 1e-09
gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] 61 7e-09
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
[Homo sapiens]
Length = 1214
Score = 2494 bits (6463), Expect = 0.0
Identities = 1214/1214 (100%), Positives = 1214/1214 (100%)
Query: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK
Sbjct: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
Query: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS
Sbjct: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV
Sbjct: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
Query: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI
Sbjct: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
Query: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV
Sbjct: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
Query: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV
Sbjct: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
Query: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY
Sbjct: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
Query: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS
Sbjct: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
Query: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER
Sbjct: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
Query: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS
Sbjct: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
Query: 661 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 720
EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR
Sbjct: 661 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 720
Query: 721 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 780
LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL
Sbjct: 721 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 780
Query: 781 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 840
PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS
Sbjct: 781 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 840
Query: 841 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 900
SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK
Sbjct: 841 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 900
Query: 901 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 960
TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK
Sbjct: 901 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 960
Query: 961 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 1020
STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP
Sbjct: 961 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 1020
Query: 1021 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED 1080
SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED
Sbjct: 1021 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED 1080
Query: 1081 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE 1140
SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE
Sbjct: 1081 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE 1140
Query: 1141 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS 1200
HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS
Sbjct: 1141 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS 1200
Query: 1201 KVQGEQSSETSDSD 1214
KVQGEQSSETSDSD
Sbjct: 1201 KVQGEQSSETSDSD 1214
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
[Homo sapiens]
Length = 1220
Score = 2487 bits (6446), Expect = 0.0
Identities = 1214/1220 (99%), Positives = 1214/1220 (99%), Gaps = 6/1220 (0%)
Query: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK
Sbjct: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
Query: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS
Sbjct: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV
Sbjct: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
Query: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI
Sbjct: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
Query: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV
Sbjct: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
Query: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV
Sbjct: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
Query: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY
Sbjct: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
Query: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS
Sbjct: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
Query: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER
Sbjct: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
Query: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS
Sbjct: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
Query: 661 ------EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 714
EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF
Sbjct: 661 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 720
Query: 715 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 774
YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL
Sbjct: 721 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 780
Query: 775 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 834
ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP
Sbjct: 781 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 840
Query: 835 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 894
ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF
Sbjct: 841 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 900
Query: 895 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 954
SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS
Sbjct: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 960
Query: 955 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1014
DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD
Sbjct: 961 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1020
Query: 1015 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1074
RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW
Sbjct: 1021 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1080
Query: 1075 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1134
LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM
Sbjct: 1081 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1140
Query: 1135 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1194
TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR
Sbjct: 1141 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1200
Query: 1195 ALQHRSKVQGEQSSETSDSD 1214
ALQHRSKVQGEQSSETSDSD
Sbjct: 1201 ALQHRSKVQGEQSSETSDSD 1220
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 1125 bits (2909), Expect = 0.0
Identities = 620/1236 (50%), Positives = 800/1236 (64%), Gaps = 116/1236 (9%)
Query: 58 LRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLD 117
+RK ++K RQ+ ++SPSP + SP RE ++YAQAQR+VEVD+ GR+HRISI+D L
Sbjct: 1 MRKPRRKSRQNAEG-RRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLK 59
Query: 118 VVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLP 177
+++EDE ++ E SNKEN+E P KS K +K K+K+S H ++ T+ LP
Sbjct: 60 IITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKH----ASGTSFHLP 115
Query: 178 EVVYRELEQDT-PDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEG 236
+ +R ++ P+APP P +YYRYIEK E+LD EVEYDMDEED WLD++NE+R+ +G
Sbjct: 116 QPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDG 175
Query: 237 VSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMC 296
S + + FE L+DRLEKESY ES + G +L+DEDA CC+C D EC NSNVILFCD+C
Sbjct: 176 HSLVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDIC 235
Query: 297 NLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALW 356
NLAVHQECYGVPYIPEGQWLCR CLQSPSR VDC LCPNKGGAFKQT DG WAHVVCA+W
Sbjct: 236 NLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIW 295
Query: 357 IPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQ 416
IPEVCFANTVFLEPI+ I++IPPARWKLTCYICKQ+G GA IQCHK NCYTAFHVTCAQ+
Sbjct: 296 IPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQR 355
Query: 417 AGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPG--SARRL-------------PALSH 461
AGL+MK+EP+RET NGT F+VRKTAYC+ H+PPG +ARR L
Sbjct: 356 AGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKE 415
Query: 462 SEGEEDE----DEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKR-----AAAPVVS 512
+GEE+E +EEE E +G S +K KS++ +K+ K E+ + P+++
Sbjct: 416 GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLA 475
Query: 513 VPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQ 572
VP IP +RL+KI + L+ QRK+QFMQRLH+YW LKRQ+RNGVPL+RRL +HLQSQRN +Q
Sbjct: 476 VPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQ 535
Query: 573 VGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTP 632
R+ ++K A+KE+LK WQ+LRHDLERARLL+ELIRKREKLKRE +KVQQ AME++L P
Sbjct: 536 --REQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMP 593
Query: 633 FLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDD 692
F +LLR TL+ LQEKD +IF+EPV LSEVPDYL+ I KPMDF TM++ LE++ Y ++
Sbjct: 594 FNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEE 653
Query: 693 FEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHS 752
FEEDFNLIV+NC+KYNAKDTIF+RAAVRLR+ GGA+LR ARRQAE +G D E G H+P S
Sbjct: 654 FEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPES 713
Query: 753 LAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMI 812
++ + + + + +++ EN+ HL E QLK LLE+LD V+A + S R+RR +++
Sbjct: 714 PKLEDFYRFSWE--DVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRVRLL 771
Query: 813 KKEMTALRRKLAHQ--------RETGRDGPERHGPSSRG-------------------SL 845
++E+ ALR+KLA +T +G GP S
Sbjct: 772 RREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSK 831
Query: 846 TPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPP 905
P P + G S +E+ S E N S P+ + R +++ P
Sbjct: 832 LPPPPTLEPTGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRK----VEEDELLEKSP 887
Query: 906 KRPGRPPK---------NRESQMTP-SHGGSPVGPPQLPIMSSLRQRKRG----RSP--- 948
+ G P NR S M P + G+P+ ++ K G RSP
Sbjct: 888 LQLGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRSPDRV 947
Query: 949 -----------RPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSL-PR 996
P+S + + ++ + P + G P ++ N
Sbjct: 948 LENGEDHGVAGSPASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNGFGKHTE 1007
Query: 997 SSSDSESSSSSSSSAASDRTS-TTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGT 1055
S SDSE S S A + S TP K+ RGKP+ SR F E G ++ G+
Sbjct: 1008 SGSDSECSLGLSGGLAFEACSGLTPPKRSRGKPALSRVPFLE-------GVNGDSDYNGS 1060
Query: 1056 GRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFH 1115
GR + L ++ L+ L+LVWAKCRGYPSYPALIIDPKMPREG+ H
Sbjct: 1061 GRSL--------------LLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLH 1106
Query: 1116 HGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEK 1175
+GVPIPVPPL+VLKLGEQ EA E L+LVLFFDNKRTWQWLPR K++PLGV +DK K
Sbjct: 1107 NGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLK 1166
Query: 1176 MLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETS 1211
MLEGRK++IRKSVQ+AY RA+ H S+V+G S TS
Sbjct: 1167 MLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTS 1202
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 1108 bits (2866), Expect = 0.0
Identities = 600/1159 (51%), Positives = 755/1159 (65%), Gaps = 108/1159 (9%)
Query: 62 KKKGRQSRPANKQSPS-PSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
++KGR R + + PS P V SP RE ++YAQAQRMVE+++ GR+HRISIFD L+++
Sbjct: 2 RRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIIL 61
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKE-KRKDSNHHHHHNVSASTTPKLPEV 179
ED+ +E E SNKEN+E P ++ +HKN K+K+ H AS + LPE
Sbjct: 62 EDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASA-LPEP 120
Query: 180 VYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSP 239
R +E P AP RP YY++IEKSAEELD EVEYDMDEEDY WL+I+NE+RK + V
Sbjct: 121 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA 180
Query: 240 IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLA 299
+ Q +FE+LMDR EKES+ E+ +G+ +L+DEDAVCCIC DGECQNSNVILFCDMCNLA
Sbjct: 181 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA 240
Query: 300 VHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPE 359
VHQECYGVPYIPEGQWLCR CLQS +R DC LCPNKGGAFK+TDD RW HVVCALWIPE
Sbjct: 241 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE 300
Query: 360 VCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGL 419
V FANTVF+EPID + +IPPARWKLTCY+CKQ+G GACIQCHKANCYTAFHVTCAQ+AGL
Sbjct: 301 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL 360
Query: 420 YMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWS 479
YMKMEPV+E GT+FSVRKTAYCD+HTPPG RR P + + E E S
Sbjct: 361 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRR-PLNIYGDVEMKNGVCRKE----S 415
Query: 480 SEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQR 539
S K ++ +K R K KKA+K LAE A P V P IPP RL++I N++ IQRK QF++R
Sbjct: 416 SVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVER 475
Query: 540 LHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLE 599
HSYW LKR SRNG PLLRRLQ+ LQSQR+ Q R+++++ A KE+LK WQRLRHDLE
Sbjct: 476 AHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQ--RENDEEMKAAKEKLKYWQRLRHDLE 533
Query: 600 RARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPL 659
RARLL+EL+RKREKLKRE +KV+Q+AME++LTP +LLR L+QLQ+KD IF++PV L
Sbjct: 534 RARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPVSL 593
Query: 660 SEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAV 719
EVPDYLDHIK PMDF TM++ LEA Y N +FEEDF+LI+ NC+KYNA+DT+FYRAAV
Sbjct: 594 KEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAV 653
Query: 720 RLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKH 779
RLR+QGG VLRQARR+ + +G++ +GMH+P A A + +RL+ N+ H
Sbjct: 654 RLRDQGGVVLRQARREVDSIGLEEASGMHLPERPAA--APRRPFSWEDVDRLLDPANRAH 711
Query: 780 LPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGP 839
L +EEQL+ LL+ LD A K S RS+RAK++KKE+ LR KL+ Q P GP
Sbjct: 712 LGLEEQLRELLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQ----PLPTGP 767
Query: 840 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFS--KK 897
G +E LGP EV R L K+
Sbjct: 768 GLEG-----------------------FEEDGAALGPE----AGEEVLPRLETLLQPRKR 800
Query: 898 NPKTAGPPK-RPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDS 956
+ T G + P K ++ +T GG+
Sbjct: 801 SRSTCGDSEVEEESPGKRLDAGLTNGFGGA------------------------------ 830
Query: 957 DSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRT 1016
+S ++P GG K + R C+ S S S S SS A
Sbjct: 831 ---RSEQEP----------GGGLGRKAT---PRRRCASESSISSSNSPLCDSSFNA---- 870
Query: 1017 STTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLS 1076
K GRGKP+ R ED SE S EN Y+ + + +G+ + W+S
Sbjct: 871 ----PKCGRGKPALVRRHTLEDRSELISCIENGNYAKA-------ARIAAEVGQSSMWIS 919
Query: 1077 ED-EDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMT 1135
D S L+ L +VWAKC GYPSYPALIIDPKMPR H+GV IP PPL+VLK+GE M
Sbjct: 920 TDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQ 979
Query: 1136 QEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRA 1195
++ E L+LVLFFDNKR+WQWLP++K+VPLG+++ +DK KM+EGR S+IRK+V+IA+ RA
Sbjct: 980 TKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVRIAFDRA 1039
Query: 1196 LQHRSKVQGEQSSETSDSD 1214
+ H S+V GE +S+ SD D
Sbjct: 1040 MNHLSRVHGEPTSDLSDID 1058
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 224 bits (570), Expect = 5e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
Query: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
Query: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
Query: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
Query: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
Query: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
V V + + + +++YW LKR+S PL +
Sbjct: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
Query: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
Query: 630 L 630
+
Sbjct: 511 V 511
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 224 bits (570), Expect = 5e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
Query: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
Query: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
Query: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
Query: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
Query: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
V V + + + +++YW LKR+S PL +
Sbjct: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
Query: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
Query: 630 L 630
+
Sbjct: 511 V 511
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 218 bits (555), Expect = 3e-56
Identities = 138/429 (32%), Positives = 201/429 (46%), Gaps = 55/429 (12%)
Query: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
Query: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
Query: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
Query: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
Query: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
Query: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
Query: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARLLVELIRKREKL 614
+ E+ N A +EQ L+ + LR DLER R L ++ +REK+
Sbjct: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKI 515
Query: 615 KRETIKVQQ 623
KR KVQ+
Sbjct: 516 KRSVCKVQE 524
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 206 bits (524), Expect = 1e-52
Identities = 142/461 (30%), Positives = 211/461 (45%), Gaps = 56/461 (12%)
Query: 176 LPEVVYRELEQ-DTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKT 234
+PE V R L + P A P+S E S + YD+DE D WL+++N K
Sbjct: 98 IPEPVVRILPPLEGPPAQASPSSTMLG-EGSQPDWPGGSRYDLDEIDAYWLELINSELKE 156
Query: 235 EGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV----DEDAVCCICNDGECQNSNVI 290
+ + E +++ LE + + + DED VC +C E ++ N +
Sbjct: 157 MERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEM 216
Query: 291 LFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDG-RWA 349
+FCD CN+ VHQ CYG+ +P G WLCR C C LCP +GGA K T G +W
Sbjct: 217 VFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQ--PKCLLCPKRGGALKPTRSGTKWV 274
Query: 350 HVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAF 409
HV CALWIPEV +EPI I HIP +RW L+C +CK+ +G CIQC +C TAF
Sbjct: 275 HVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKE-CTGTCIQCSMPSCVTAF 333
Query: 410 HVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDED 469
HVTCA GL M+ + V+ ++C H+ G E +
Sbjct: 334 HVTCAFDHGLEMRT-------ILADNDEVKFKSFCQEHSDGG----------PRNEPTSE 376
Query: 470 EEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLT 529
E G EKV K + + ++++ L E +++ RL
Sbjct: 377 PTEPSQAGEDLEKVTLRKQRLQ-QLEEDFYELVEP-----------------AEVAERLD 418
Query: 530 IQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLK 589
+ + ++ YW LKR++ PLL D+V ++ + L +LK
Sbjct: 419 L--AEALVDFIYQYWKLKRKANANQPLL---------TPKTDEVDNLAQQEQDVLYRRLK 467
Query: 590 SWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQL 630
+ LR DLER R L ++ +RE+ K K+Q+ +Q+
Sbjct: 468 LFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQM 508
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 198 bits (504), Expect = 2e-50
Identities = 128/409 (31%), Positives = 187/409 (45%), Gaps = 55/409 (13%)
Query: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
Query: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
Query: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
Query: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
Query: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
Query: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
Query: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARL 603
+ E+ N A +EQ L+ + LR DLER +
Sbjct: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVMI 504
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 172 bits (437), Expect = 1e-42
Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)
Query: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN +EPI ++ +P R+ TCYIC +
Sbjct: 84 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445
+G +GAC+ C+K C AFHVTCAQ AGL + E NG +V+ YC
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
Query: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491
H + GS R +LS S + E E K + + K K K +
Sbjct: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 172 bits (437), Expect = 1e-42
Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)
Query: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN +EPI ++ +P R+ TCYIC +
Sbjct: 84 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445
+G +GAC+ C+K C AFHVTCAQ AGL + E NG +V+ YC
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
Query: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491
H + GS R +LS S + E E K + + K K K +
Sbjct: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 172 bits (435), Expect = 2e-42
Identities = 105/279 (37%), Positives = 151/279 (54%), Gaps = 54/279 (19%)
Query: 276 CCICNDGECQNSNVILFCD--MCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 66
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN + +EPI ++++P R+ TCYIC++
Sbjct: 67 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPI-VLQYVPHDRFNKTCYICEE 125
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGL-----YMKMEPVRETGANGTSFSVRK 440
+G SGAC+ C++ C AFHVTCAQ AGL ++++ V+ G FS K
Sbjct: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
Query: 441 TAYCDIHTPPG--------------------SARRLPALSHSEGEEDEDEEEDEGKGWSS 480
T+ H+ G S RR + S S +E + G
Sbjct: 186 TSR---HSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG----- 237
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAP--VVSVPCIP 517
+ K K K R+K K +KR +P +++ P +P
Sbjct: 238 -QKKSRKDKERLKQKH------KKRPESPPSILTPPVVP 269
Score = 32.0 bits (71), Expect = 3.7
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 30/200 (15%)
Query: 840 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 899
SS + P P T S A + + P +S+TP + L KK+
Sbjct: 415 SSGRARAPSPGDYKSPHVTGSGASAGTHKRM-----PALSATPVPADETPETGLKEKKHK 469
Query: 900 KTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIM----------------SSLRQRK 943
+ PGRP +R + T G P P LP S +
Sbjct: 470 ASKRSRHGPGRPKGSRNKEGT----GGPAA-PSLPSAQLAGFTATAASPFSGGSLVSSGL 524
Query: 944 RGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSS--DS 1001
G S R S S S E P L A ++ P+ S + R CS P SSS
Sbjct: 525 GGLSSRTFGPSGSLPSLSLESPL--LGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGP 582
Query: 1002 ESSSSSSSSAASDRTSTTPS 1021
+S+ + S TST PS
Sbjct: 583 PGTSALPRLSRSPFTSTLPS 602
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 130 bits (326), Expect = 1e-29
Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422
ID + IP R KL C C+ +R SGACIQC C +FHVTCA AG+ M+
Sbjct: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 130 bits (326), Expect = 1e-29
Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422
ID + IP R KL C C+ +R SGACIQC C +FHVTCA AG+ M+
Sbjct: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 126 bits (316), Expect = 1e-28
Identities = 62/137 (45%), Positives = 80/137 (58%), Gaps = 6/137 (4%)
Query: 290 ILFCDMCNLAVHQECYGV-PYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRW 348
++ C C L VH CYG+ P + W C RC A +C LC +GGA + T D RW
Sbjct: 757 LIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTA-ECCLCNLRGGALQMTTDRRW 815
Query: 349 AHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQR---GSGACIQCHKANC 405
HV+CA+ +PE F N + P+D I IP RWKL C C++R SGACIQC +C
Sbjct: 816 IHVICAIAVPEARFLNVIERHPVD-ISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHC 874
Query: 406 YTAFHVTCAQQAGLYMK 422
T+FHVTCA AG+ M+
Sbjct: 875 STSFHVTCAHAAGVLME 891
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 121 bits (303), Expect = 5e-27
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 6/144 (4%)
Query: 283 ECQNSNVILFCDMCNLAVHQECYGVPYIPEGQ-WLCRRCLQSPSRAVDCALCPNKGGAFK 341
E +++++ C C++ VH CYGVP + W+C RC + + DC LC +GGA +
Sbjct: 728 EEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQ 786
Query: 342 QTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICK---QRGSGACI 398
+ +D RW HV CA+ I E F N P+D + IP R+KL C CK +R +G C+
Sbjct: 787 RANDDRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
Query: 399 QCHKANCYTAFHVTCAQQAGLYMK 422
QC C TAFHV+CAQ AG+ M+
Sbjct: 846 QCSHGRCPTAFHVSCAQAAGVMMQ 869
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 114 bits (286), Expect = 4e-25
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 20/166 (12%)
Query: 270 VDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEG-----------QWLCR 318
+D +CC+C ++++ I+ CD C + VH+ CYGV + W C
Sbjct: 316 MDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCD 375
Query: 319 --RCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEH 376
+C SPS C LCPN+ G FK+TD GRW H+VCAL++P V F + L P+ E
Sbjct: 376 ACKCGVSPS----CELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEM 431
Query: 377 IPPARWKLTCYICKQ---RGSGACIQCHKANCYTAFHVTCAQQAGL 419
C C+ +G CI C C FHVTCAQ+ GL
Sbjct: 432 NYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGL 477
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 114 bits (286), Expect = 4e-25
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 20/166 (12%)
Query: 270 VDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEG-----------QWLCR 318
+D +CC+C ++++ I+ CD C + VH+ CYGV + W C
Sbjct: 316 MDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCD 375
Query: 319 --RCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEH 376
+C SPS C LCPN+ G FK+TD GRW H+VCAL++P V F + L P+ E
Sbjct: 376 ACKCGVSPS----CELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEM 431
Query: 377 IPPARWKLTCYICKQ---RGSGACIQCHKANCYTAFHVTCAQQAGL 419
C C+ +G CI C C FHVTCAQ+ GL
Sbjct: 432 NYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGL 477
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 90.5 bits (223), Expect = 9e-18
Identities = 84/314 (26%), Positives = 130/314 (41%), Gaps = 53/314 (16%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKL 384
ID + IP R KL
Sbjct: 796 ID-VGRIPLQRLKL 808
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 90.5 bits (223), Expect = 9e-18
Identities = 84/314 (26%), Positives = 130/314 (41%), Gaps = 53/314 (16%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 563 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 622
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 623 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 681
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 682 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 720
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 721 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 759
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 760 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 817
Query: 371 IDSIEHIPPARWKL 384
ID + IP R KL
Sbjct: 818 ID-VGRIPLQRLKL 830
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 87.4 bits (215), Expect = 7e-17
Identities = 82/287 (28%), Positives = 133/287 (46%), Gaps = 18/287 (6%)
Query: 574 GRDSEDKNWALKEQLKSWQRLRHDLERARLL-----VELIRKREKLKRETIKVQQIAMEM 628
G + K +KE K R R + E + L V L EK ++ Q+ E+
Sbjct: 75 GEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQE---EV 131
Query: 629 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYL 688
+ TP L + + QLQ KD FS PV P Y IK PMDF TMK+ ++ Y
Sbjct: 132 EQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQ 191
Query: 689 NFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMH 748
+ ++ +++F L+ +N + YN +TI+Y+AA +L G +L Q R Q+ K IDF +
Sbjct: 192 SIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMADLQ 251
Query: 749 IPHSLA-GDEATHHTEDAA--EEERLVLLENQKHL---PVEEQLKLLLERL-DEVNASKQ 801
G + + ED + ER + + H P +E K + L D+ ++
Sbjct: 252 KTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKDMLEDKFKSNNL 311
Query: 802 SVGRSRRAKMIKKEMTALRRKLAH-QRETGRDGPERHGPSSRGSLTP 847
+ + +++K+ L R+L + Q E R P+ G ++ G L P
Sbjct: 312 EREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPD--GTTTLGLLHP 356
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 74.7 bits (182), Expect = 5e-13
Identities = 42/114 (36%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYR 686
E + TP LL L QLQ KD F+ PV + P Y IK PMDF TMK + A
Sbjct: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANE 194
Query: 687 YLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG 740
Y + +F+ DF L+ N + YN DT++Y+ A ++ G + +QA +G
Sbjct: 195 YKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALLG 245
>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
Length = 1458
Score = 69.3 bits (168), Expect = 2e-11
Identities = 46/155 (29%), Positives = 68/155 (43%), Gaps = 16/155 (10%)
Query: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYR 686
E L + LR ++L NIFS+PV + EV DYL+ IK+PMD T+ ++ +
Sbjct: 957 ENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHN 1016
Query: 687 YLNFDDFEEDFNLIVSNCLKYN----------------AKDTIFYRAAVRLREQGGAVLR 730
YL DF +D +LI SN L+YN KDT A L + +
Sbjct: 1017 YLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCE 1076
Query: 731 QARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 765
+ + K G+ + PHS + E+A
Sbjct: 1077 EIKEARIKRGLSVTSEQINPHSTGARKTETRVEEA 1111
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 67.4 bits (163), Expect = 8e-11
Identities = 97/402 (24%), Positives = 166/402 (41%), Gaps = 46/402 (11%)
Query: 653 FSEPVPLS--EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
F +PV E+ DY D IK PMD T+K+ ++ Y + F D L+ SNC KYN
Sbjct: 334 FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP 393
Query: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA----- 765
D A +L Q +R A+ E + P G E++ +E++
Sbjct: 394 DHEVVAMARKL--QDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSG 451
Query: 766 ---AEEERLV-LLENQKHL-PVEEQLKLLLER-LDEVNASKQSVGRSRRAKMIKKE---- 815
+EEER L E Q+ L V EQL L + +++ K+ + ++ K +KE
Sbjct: 452 SSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKH 511
Query: 816 -MTALRRKLAHQRETGRDGPERHGPSSR-GSLTPHPAACDKDGQTDSAAEESSSQE---- 869
+ A K A + ++ P+ + S T K G+ SA+ +S +E
Sbjct: 512 KVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLP 571
Query: 870 ----TSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGG 925
+ L +++ P ++GR ++ S++ P R P + T
Sbjct: 572 MSYDEKRQLSLDINRLPGEKLGRVVHIIQSRE------PSLRDSNPDEIEIDFETLK--P 623
Query: 926 SPVGPPQLPIMSSLRQRKR------GRSPRPSSSSDSDSDKSTE-DPPMDLPANGFSGGN 978
+ + + + S L++++R G+ S + +K E + + + S
Sbjct: 624 TTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSK 683
Query: 979 QPVKKS--FLVYRNDCSLPRSSSDSESSSSSSSSAASDRTST 1018
+P +K S SSS SES SSSSS ++SD + +
Sbjct: 684 KPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDS 725
Score = 43.1 bits (100), Expect = 0.002
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 653 FSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 708
F +PV ++ PDY IK PMD T+K+ LE Y + + +DFN + +NC YN
Sbjct: 59 FYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
Score = 32.3 bits (72), Expect = 2.8
Identities = 40/152 (26%), Positives = 58/152 (38%), Gaps = 22/152 (14%)
Query: 839 PSSRGSLTPHPAACDKDGQTDSAAEESSSQETS-KGLGPNMSSTP---AHEVGRRTSVLF 894
P+ +G A G AA S S T + + P +S TP A V T+ +
Sbjct: 150 PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
Query: 895 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSS- 953
S P A PP PP TP PV PP P++ +++ + P++S
Sbjct: 210 SVPVPPAAAPP-----PPA------TPI---VPVVPPTPPVVKKKGVKRKADTTTPTTSA 255
Query: 954 ---SDSDSDKSTEDPPMDLPANGFSGGNQPVK 982
S S+S DP G +P+K
Sbjct: 256 ITASRSESPPPLSDPKQAKVVARRESGGRPIK 287
Score = 31.2 bits (69), Expect = 6.3
Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 52 PPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRIS 111
P P KG +S ++++S S S S S A+ Q
Sbjct: 423 PALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQ--------------- 467
Query: 112 IFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRK 158
+ L V E A +AP N K+ + K K K KEK K
Sbjct: 468 --EQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHK 512
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 66.2 bits (160), Expect = 2e-10
Identities = 91/398 (22%), Positives = 153/398 (38%), Gaps = 64/398 (16%)
Query: 653 FSEPVPLSEVP--DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
F +PV + + DY D IK PMD T+K LEA Y + +F D L+ SNC KYN
Sbjct: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
Query: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIP-------------HSLAGDE 757
D A +L++ + + E+ + + P S + +
Sbjct: 436 DHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
Query: 758 ATHHTEDAAEEERLVLLENQKHL-PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEM 816
+ T+D+ EE L E Q+ L V EQL L + K+ + ++ + K++
Sbjct: 496 SDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKE 555
Query: 817 TALRRKLAHQRETGRDGPERHGPSSRGSLTPHPAAC-DKDGQTDSAAEESS----SQETS 871
K + +E +++ S+ PA K T + EE S E
Sbjct: 556 EVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEK 615
Query: 872 KGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPP 931
+ L +++ P ++GR ++ S++ P P E + S +
Sbjct: 616 RQLSLDINKLPGEKLGRVVHIIQSRE-------PSLKNSNPDEIEIDF-ETLKPSTLREL 667
Query: 932 QLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRND 991
+ + S LR++++ ++ + + S K GF
Sbjct: 668 ERYVTSCLRKKRKPQAEKVDVIAGSSKMK------------GF----------------- 698
Query: 992 CSLPRSSSDSESSSSSSSSAASD-RTSTTPSKQGRGKP 1028
SSS+SESSS SSSS + D T P + +G P
Sbjct: 699 -----SSSESESSSESSSSDSEDSETEMAPKSKKKGHP 731
Score = 48.9 bits (115), Expect = 3e-05
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 636 LLRKTLEQLQEKDTGNIFSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDF 693
LLR L+ L + F +PV ++ PDY IK PMD T+K+ LE Y N +
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQEC 125
Query: 694 EEDFNLIVSNCLKYN 708
+DFN + +NC YN
Sbjct: 126 IQDFNTMFTNCYIYN 140
Score = 39.3 bits (90), Expect = 0.023
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 124 EAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRE 183
E+ + + S+ E++ET A PKS K + + + +HHHHH +P+
Sbjct: 702 ESESSSESSSSDSEDSETEMA-PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPP 760
Query: 184 LEQDTPDAPPR 194
+Q P PP+
Sbjct: 761 PQQPPPPPPPQ 771
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 64.7 bits (156), Expect = 5e-10
Identities = 111/446 (24%), Positives = 165/446 (36%), Gaps = 99/446 (22%)
Query: 653 FSEPVPLSEVP--DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
F +PV S + DY D IK PMD T+K+ +E Y + +F D L+ SNC KYN
Sbjct: 372 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP 431
Query: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKM---GIDFETGMHIPHSLA-----------GD 756
D A +L Q R A+ E + + T M P LA
Sbjct: 432 DHDVVAMARKL--QDVFEFRYAKMPDEPLEPGPLPVSTAM--PPGLAKSSSESSSEESSS 487
Query: 757 EATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNA--------SKQSVGRSRR 808
E++ E+ +EE E++ EE+ L E +++ A S+ + + +R
Sbjct: 488 ESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKR 547
Query: 809 AKMIKKEMTALRRKLAHQRETGRD------------------------------GPERHG 838
K KKE R+ H+ G D GP G
Sbjct: 548 -KREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFG 606
Query: 839 PSSRGSLTPHPAACDKDGQT------DSAAEESS---SQETSKGLGPNMSSTPAHEVGRR 889
PS GS T P K DS EE S S + + L +++ P ++GR
Sbjct: 607 PSG-GSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRV 665
Query: 890 TSVLFSKK------NPKTAGPPKRPGRPPKNRESQ-----------MTPSHGGSPVGPPQ 932
++ +++ NP+ +P RE + P PVG +
Sbjct: 666 VHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTK 725
Query: 933 LPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDC 992
+ ++ R S + ST+ PP S Q V S
Sbjct: 726 EELALEKKRELEKRLQDVSGQLN-----STKKPPKKANEKTESSSAQQVAVS-------- 772
Query: 993 SLPRSSSDSESSSSSSSSAASDRTST 1018
L SSS S+SSSSSSSS++SD + +
Sbjct: 773 RLSASSSSSDSSSSSSSSSSSDTSDS 798
Score = 42.7 bits (99), Expect = 0.002
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 653 FSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 708
F +PV ++ PDY IK+PMD T+K+ LE Y + +DFN + +NC YN
Sbjct: 99 FRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 64.7 bits (156), Expect = 5e-10
Identities = 111/446 (24%), Positives = 165/446 (36%), Gaps = 99/446 (22%)
Query: 653 FSEPVPLSEVP--DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
F +PV S + DY D IK PMD T+K+ +E Y + +F D L+ SNC KYN
Sbjct: 372 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP 431
Query: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKM---GIDFETGMHIPHSLA-----------GD 756
D A +L Q R A+ E + + T M P LA
Sbjct: 432 DHDVVAMARKL--QDVFEFRYAKMPDEPLEPGPLPVSTAM--PPGLAKSSSESSSEESSS 487
Query: 757 EATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNA--------SKQSVGRSRR 808
E++ E+ +EE E++ EE+ L E +++ A S+ + + +R
Sbjct: 488 ESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKR 547
Query: 809 AKMIKKEMTALRRKLAHQRETGRD------------------------------GPERHG 838
K KKE R+ H+ G D GP G
Sbjct: 548 -KREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFG 606
Query: 839 PSSRGSLTPHPAACDKDGQT------DSAAEESS---SQETSKGLGPNMSSTPAHEVGRR 889
PS GS T P K DS EE S S + + L +++ P ++GR
Sbjct: 607 PSG-GSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRV 665
Query: 890 TSVLFSKK------NPKTAGPPKRPGRPPKNRESQ-----------MTPSHGGSPVGPPQ 932
++ +++ NP+ +P RE + P PVG +
Sbjct: 666 VHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTK 725
Query: 933 LPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDC 992
+ ++ R S + ST+ PP S Q V S
Sbjct: 726 EELALEKKRELEKRLQDVSGQLN-----STKKPPKKANEKTESSSAQQVAVS-------- 772
Query: 993 SLPRSSSDSESSSSSSSSAASDRTST 1018
L SSS S+SSSSSSSS++SD + +
Sbjct: 773 RLSASSSSSDSSSSSSSSSSSDTSDS 798
Score = 42.7 bits (99), Expect = 0.002
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 653 FSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 708
F +PV ++ PDY IK+PMD T+K+ LE Y + +DFN + +NC YN
Sbjct: 99 FRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 63.5 bits (153), Expect = 1e-09
Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 10/135 (7%)
Query: 614 LKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPM 673
L E +K + E I LR +L +F++PV EVPDY+ IK+PM
Sbjct: 970 LTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPM 1029
Query: 674 DFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK----DTIFYRAAVRLREQGGAVL 729
D ++ ++ ++YL D+ D +LI SN L+YN D + A LR+ A++
Sbjct: 1030 DLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAII 1089
Query: 730 RQARRQAEKMGIDFE 744
+ E++ DFE
Sbjct: 1090 K------EELDEDFE 1098
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 63.2 bits (152), Expect = 1e-09
Identities = 78/341 (22%), Positives = 132/341 (38%), Gaps = 29/341 (8%)
Query: 653 FSEPVPLSEVP--DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
F +PV + + DY D IK PMD T+K LEA Y + +F D L+ SNC KYN
Sbjct: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
Query: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIP-------------HSLAGDE 757
D A +L++ + + E+ + + P S + +
Sbjct: 436 DHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
Query: 758 ATHHTEDAAEEERLVLLENQKHL-PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEM 816
+ T+D+ EE L E Q+ L V EQL L + K+ + ++ + K++
Sbjct: 496 SDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKE 555
Query: 817 TALRRKLAHQRETGRDGPERHGPSSRGSLTPHPAAC-DKDGQTDSAAEESS----SQETS 871
K + +E +++ S+ PA K T + EE S E
Sbjct: 556 EVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEK 615
Query: 872 KGLGPNMSSTPAHEVGRRTSVLFSKK------NPKTAGPPKRPGRPPKNRESQMTPSHGG 925
+ L +++ P ++GR ++ S++ NP +P RE + +
Sbjct: 616 RQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCL 675
Query: 926 SPVGPPQLPIMSSL--RQRKRGRSPRPSSSSDSDSDKSTED 964
PQ + + + +G S S SS S +ED
Sbjct: 676 RKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSED 716
Score = 48.9 bits (115), Expect = 3e-05
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 636 LLRKTLEQLQEKDTGNIFSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDF 693
LLR L+ L + F +PV ++ PDY IK PMD T+K+ LE Y N +
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQEC 125
Query: 694 EEDFNLIVSNCLKYN 708
+DFN + +NC YN
Sbjct: 126 IQDFNTMFTNCYIYN 140
>gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]
Length = 544
Score = 60.8 bits (146), Expect = 7e-09
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 647 KDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLK 706
+D F+ PV + P Y IK PMDF TMK + A Y + +F+ DF L+ N +
Sbjct: 102 RDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMT 161
Query: 707 YNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG 740
YN DT++Y+ A ++ G + +QA +G
Sbjct: 162 YNRPDTVYYKLAKKILHAG---FKMMSKQAALLG 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,222,381
Number of Sequences: 37866
Number of extensions: 3040641
Number of successful extensions: 23292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 723
Number of HSP's that attempted gapping in prelim test: 17439
Number of HSP's gapped (non-prelim): 5071
length of query: 1214
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1100
effective length of database: 13,930,794
effective search space: 15323873400
effective search space used: 15323873400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.