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Search of human proteins with 51173720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51173720 bromodomain and PHD finger-containing protein 1
isoform 1 [Homo sapiens]
(1220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 2505 0.0
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 2487 0.0
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 1118 0.0
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 1102 0.0
gi|117190334 PHD finger protein 16 [Homo sapiens] 224 5e-58
gi|7662006 PHD finger protein 16 [Homo sapiens] 224 5e-58
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 218 3e-56
gi|40556370 PHD finger protein 15 [Homo sapiens] 206 1e-52
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 198 2e-50
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 172 1e-42
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 172 1e-42
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 172 2e-42
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 130 1e-29
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 130 1e-29
gi|45504380 jumonji domain containing 2B [Homo sapiens] 126 1e-28
gi|98986459 jumonji domain containing 2A [Homo sapiens] 121 5e-27
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 114 4e-25
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 114 4e-25
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 91 9e-18
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 91 9e-18
gi|41350212 bromodomain containing 7 [Homo sapiens] 82 3e-15
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 69 4e-11
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 67 1e-10
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 66 2e-10
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 65 5e-10
gi|164419758 bromodomain containing 2 [Homo sapiens] 64 1e-09
gi|4826806 bromodomain containing 2 [Homo sapiens] 64 1e-09
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 63 2e-09
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 60 1e-08
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 56 2e-07
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
[Homo sapiens]
Length = 1220
Score = 2505 bits (6492), Expect = 0.0
Identities = 1220/1220 (100%), Positives = 1220/1220 (100%)
Query: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK
Sbjct: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
Query: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS
Sbjct: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV
Sbjct: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
Query: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI
Sbjct: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
Query: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV
Sbjct: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
Query: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV
Sbjct: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
Query: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY
Sbjct: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
Query: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS
Sbjct: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
Query: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER
Sbjct: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
Query: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS
Sbjct: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
Query: 661 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 720
EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF
Sbjct: 661 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 720
Query: 721 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 780
YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL
Sbjct: 721 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 780
Query: 781 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 840
ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP
Sbjct: 781 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 840
Query: 841 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 900
ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF
Sbjct: 841 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 900
Query: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 960
SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS
Sbjct: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 960
Query: 961 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1020
DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD
Sbjct: 961 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1020
Query: 1021 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1080
RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW
Sbjct: 1021 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1080
Query: 1081 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1140
LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM
Sbjct: 1081 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1140
Query: 1141 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1200
TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR
Sbjct: 1141 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1200
Query: 1201 ALQHRSKVQGEQSSETSDSD 1220
ALQHRSKVQGEQSSETSDSD
Sbjct: 1201 ALQHRSKVQGEQSSETSDSD 1220
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
[Homo sapiens]
Length = 1214
Score = 2487 bits (6446), Expect = 0.0
Identities = 1214/1220 (99%), Positives = 1214/1220 (99%), Gaps = 6/1220 (0%)
Query: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK
Sbjct: 1 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 60
Query: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS
Sbjct: 61 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV
Sbjct: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 180
Query: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI
Sbjct: 181 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 240
Query: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV
Sbjct: 241 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 300
Query: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV
Sbjct: 301 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 360
Query: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY
Sbjct: 361 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 420
Query: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS
Sbjct: 421 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 540
Query: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER
Sbjct: 541 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 600
Query: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS
Sbjct: 601 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 660
Query: 661 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 720
EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF
Sbjct: 661 ------EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 714
Query: 721 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 780
YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL
Sbjct: 715 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 774
Query: 781 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 840
ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP
Sbjct: 775 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 834
Query: 841 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 900
ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF
Sbjct: 835 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 894
Query: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 960
SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS
Sbjct: 895 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 954
Query: 961 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1020
DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD
Sbjct: 955 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 1014
Query: 1021 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1080
RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW
Sbjct: 1015 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1074
Query: 1081 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1140
LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM
Sbjct: 1075 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1134
Query: 1141 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1200
TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR
Sbjct: 1135 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1194
Query: 1201 ALQHRSKVQGEQSSETSDSD 1220
ALQHRSKVQGEQSSETSDSD
Sbjct: 1195 ALQHRSKVQGEQSSETSDSD 1214
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 1118 bits (2892), Expect = 0.0
Identities = 620/1242 (49%), Positives = 800/1242 (64%), Gaps = 122/1242 (9%)
Query: 58 LRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLD 117
+RK ++K RQ+ ++SPSP + SP RE ++YAQAQR+VEVD+ GR+HRISI+D L
Sbjct: 1 MRKPRRKSRQNAEG-RRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLK 59
Query: 118 VVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLP 177
+++EDE ++ E SNKEN+E P KS K +K K+K+S H ++ T+ LP
Sbjct: 60 IITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKH----ASGTSFHLP 115
Query: 178 EVVYRELEQDT-PDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEG 236
+ +R ++ P+APP P +YYRYIEK E+LD EVEYDMDEED WLD++NE+R+ +G
Sbjct: 116 QPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDG 175
Query: 237 VSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMC 296
S + + FE L+DRLEKESY ES + G +L+DEDA CC+C D EC NSNVILFCD+C
Sbjct: 176 HSLVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDIC 235
Query: 297 NLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALW 356
NLAVHQECYGVPYIPEGQWLCR CLQSPSR VDC LCPNKGGAFKQT DG WAHVVCA+W
Sbjct: 236 NLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIW 295
Query: 357 IPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQ 416
IPEVCFANTVFLEPI+ I++IPPARWKLTCYICKQ+G GA IQCHK NCYTAFHVTCAQ+
Sbjct: 296 IPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQR 355
Query: 417 AGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPG--SARRL-------------PALSH 461
AGL+MK+EP+RET NGT F+VRKTAYC+ H+PPG +ARR L
Sbjct: 356 AGLFMKIEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKE 415
Query: 462 SEGEEDE----DEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKR-----AAAPVVS 512
+GEE+E +EEE E +G S +K KS++ +K+ K E+ + P+++
Sbjct: 416 GDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLA 475
Query: 513 VPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQ 572
VP IP +RL+KI + L+ QRK+QFMQRLH+YW LKRQ+RNGVPL+RRL +HLQSQRN +Q
Sbjct: 476 VPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQ 535
Query: 573 VGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQLTP 632
R+ ++K A+KE+LK WQ+LRHDLERARLL+ELIRKREKLKRE +KVQQ AME++L P
Sbjct: 536 --REQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMP 593
Query: 633 FLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYR 692
F +LLR TL+ LQEKD +IF+EPV LS EVPDYL+ I KPMDF TM++ LE++
Sbjct: 594 FNVLLRTTLDLLQEKDPAHIFAEPVNLS------EVPDYLEFISKPMDFSTMRRKLESHL 647
Query: 693 YLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETG 752
Y ++FEEDFNLIV+NC+KYNAKDTIF+RAAVRLR+ GGA+LR ARRQAE +G D E G
Sbjct: 648 YRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERG 707
Query: 753 MHIPHSLAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRS 812
H+P S ++ + + + + +++ EN+ HL E QLK LLE+LD V+A + S R+
Sbjct: 708 THLPESPKLEDFYRFSWE--DVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGART 765
Query: 813 RRAKMIKKEMTALRRKLAHQ--------RETGRDGPERHGPSSRG--------------- 849
RR +++++E+ ALR+KLA +T +G GP
Sbjct: 766 RRVRLLRREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDG 825
Query: 850 ----SLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 905
S P P + G S +E+ S E N S P+ + R +++
Sbjct: 826 DRDDSKLPPPPTLEPTGPAPSLSEQESPPEPPTLKPINDSKPPSRFLKPRK----VEEDE 881
Query: 906 KTAGPPKRPGRPPK---------NRESQMTP-SHGGSPVGPPQLPIMSSLRQRKRG---- 951
P + G P NR S M P + G+P+ ++ K G
Sbjct: 882 LLEKSPLQLGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQ 941
Query: 952 RSP--------------RPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRND 997
RSP P+S + + ++ + P + G P ++ N
Sbjct: 942 RSPDRVLENGEDHGVAGSPASPASIEEERHSRKRPRSRSCSESEGERSPQQEEETGMTNG 1001
Query: 998 CSL-PRSSSDSESSSSSSSSAASDRTS-TTPSKQGRGKPSFSRGTFPEDSSEDTSGTENE 1055
S SDSE S S A + S TP K+ RGKP+ SR F E G +
Sbjct: 1002 FGKHTESGSDSECSLGLSGGLAFEACSGLTPPKRSRGKPALSRVPFLE-------GVNGD 1054
Query: 1056 AYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMP 1115
+ G+GR + L ++ L+ L+LVWAKCRGYPSYPALIIDPKMP
Sbjct: 1055 SDYNGSGRSL--------------LLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMP 1100
Query: 1116 REGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQ 1175
REG+ H+GVPIPVPPL+VLKLGEQ EA E L+LVLFFDNKRTWQWLPR K++PLGV
Sbjct: 1101 REGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVED 1160
Query: 1176 DLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETS 1217
+DK KMLEGRK++IRKSVQ+AY RA+ H S+V+G S TS
Sbjct: 1161 TVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTS 1202
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 1102 bits (2849), Expect = 0.0
Identities = 600/1165 (51%), Positives = 755/1165 (64%), Gaps = 114/1165 (9%)
Query: 62 KKKGRQSRPANKQSPS-PSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 120
++KGR R + + PS P V SP RE ++YAQAQRMVE+++ GR+HRISIFD L+++
Sbjct: 2 RRKGRCHRGSAARHPSSPCSVKHSPTRETLTYAQAQRMVEIEIEGRLHRISIFDPLEIIL 61
Query: 121 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKE-KRKDSNHHHHHNVSASTTPKLPEV 179
ED+ +E E SNKEN+E P ++ +HKN K+K+ H AS + LPE
Sbjct: 62 EDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNEALPSAHGTPASASA-LPEP 120
Query: 180 VYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSP 239
R +E P AP RP YY++IEKSAEELD EVEYDMDEEDY WL+I+NE+RK + V
Sbjct: 121 KVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDEEDYAWLEIVNEKRKGDCVPA 180
Query: 240 IPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLA 299
+ Q +FE+LMDR EKES+ E+ +G+ +L+DEDAVCCIC DGECQNSNVILFCDMCNLA
Sbjct: 181 VSQSMFEFLMDRFEKESHCENQKQGEQQSLIDEDAVCCICMDGECQNSNVILFCDMCNLA 240
Query: 300 VHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPE 359
VHQECYGVPYIPEGQWLCR CLQS +R DC LCPNKGGAFK+TDD RW HVVCALWIPE
Sbjct: 241 VHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNKGGAFKKTDDDRWGHVVCALWIPE 300
Query: 360 VCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGL 419
V FANTVF+EPID + +IPPARWKLTCY+CKQ+G GACIQCHKANCYTAFHVTCAQ+AGL
Sbjct: 301 VGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGL 360
Query: 420 YMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWS 479
YMKMEPV+E GT+FSVRKTAYCD+HTPPG RR P + + E E S
Sbjct: 361 YMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRR-PLNIYGDVEMKNGVCRKE----S 415
Query: 480 SEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQR 539
S K ++ +K R K KKA+K LAE A P V P IPP RL++I N++ IQRK QF++R
Sbjct: 416 SVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIPPQRLNRIANQVAIQRKKQFVER 475
Query: 540 LHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLE 599
HSYW LKR SRNG PLLRRLQ+ LQSQR+ Q R+++++ A KE+LK WQRLRHDLE
Sbjct: 476 AHSYWLLKRLSRNGAPLLRRLQSSLQSQRSSQQ--RENDEEMKAAKEKLKYWQRLRHDLE 533
Query: 600 RARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPL 659
RARLL+EL+RKREKLKRE +KV+Q+AME++LTP +LLR L+QLQ+KD IF++PV
Sbjct: 534 RARLLIELLRKREKLKREQVKVEQVAMELRLTPLTVLLRSVLDQLQDKDPARIFAQPV-- 591
Query: 660 SEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTI 719
L EVPDYLDHIK PMDF TM++ LEA Y N +FEEDF+LI+ NC+KYNA+DT+
Sbjct: 592 ----SLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTV 647
Query: 720 FYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVL 779
FYRAAVRLR+QGG VLRQARR+ + +G++ +GMH+P A A + +RL+
Sbjct: 648 FYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHLPERPAA--APRRPFSWEDVDRLLD 705
Query: 780 LENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDG 839
N+ HL +EEQL+ LL+ LD A K S RS+RAK++KKE+ LR KL+ Q
Sbjct: 706 PANRAHLGLEEQLRELLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQ---- 761
Query: 840 PERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVL 899
P GP G +E LGP EV R L
Sbjct: 762 PLPTGPGLEG-----------------------FEEDGAALGPE----AGEEVLPRLETL 794
Query: 900 FS--KKNPKTAGPPK-RPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRP 956
K++ T G + P K ++ +T GG+
Sbjct: 795 LQPRKRSRSTCGDSEVEEESPGKRLDAGLTNGFGGA------------------------ 830
Query: 957 SSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSS 1016
+S ++P GG K + R C+ S S S S SS
Sbjct: 831 ---------RSEQEP----------GGGLGRKAT---PRRRCASESSISSSNSPLCDSSF 868
Query: 1017 AASDRTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGR 1076
A K GRGKP+ R ED SE S EN Y+ + + +G+
Sbjct: 869 NA--------PKCGRGKPALVRRHTLEDRSELISCIENGNYAKA-------ARIAAEVGQ 913
Query: 1077 GAGWLSED-EDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLK 1135
+ W+S D S L+ L +VWAKC GYPSYPALIIDPKMPR H+GV IP PPL+VLK
Sbjct: 914 SSMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPGHHNGVTIPAPPLDVLK 973
Query: 1136 LGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQ 1195
+GE M ++ E L+LVLFFDNKR+WQWLP++K+VPLG+++ +DK KM+EGR S+IRK+V+
Sbjct: 974 IGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVPLGIDETIDKLKMMEGRNSSIRKAVR 1033
Query: 1196 IAYHRALQHRSKVQGEQSSETSDSD 1220
IA+ RA+ H S+V GE +S+ SD D
Sbjct: 1034 IAFDRAMNHLSRVHGEPTSDLSDID 1058
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 224 bits (570), Expect = 5e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
Query: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
Query: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
Query: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
Query: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
Query: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
V V + + + +++YW LKR+S PL +
Sbjct: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
Query: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
Query: 630 L 630
+
Sbjct: 511 V 511
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 224 bits (570), Expect = 5e-58
Identities = 138/421 (32%), Positives = 208/421 (49%), Gaps = 52/421 (12%)
Query: 215 YDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV---- 270
YD+D+ D WL +NE G P+ + + E ++ LE+ + ++ + +
Sbjct: 138 YDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEY 197
Query: 271 DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDC 330
DED +C +C + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C+ C
Sbjct: 198 DEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVL--GIYPQC 255
Query: 331 ALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC 389
LCP KGGA K T G +WAHV CALWIPEV A +EPI I HIPP+RW L C +C
Sbjct: 256 VLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC 315
Query: 390 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP 449
K + +GACIQC +C TAFHVTCA + GL MK + + G V+ +YC
Sbjct: 316 KLK-TGACIQCSIKSCITAFHVTCAFEHGLEMK--TILDEGD-----EVKFKSYC----- 362
Query: 450 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP 509
L HS+ + E E + E+ + K+ ++ +K R++ E +
Sbjct: 363 ---------LKHSQNRQKLGEAEYPHHR-AKEQSQAKSEKTSLRAQKLRELEEEFYSLVR 412
Query: 510 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN 569
V V + + + +++YW LKR+S PL +
Sbjct: 413 VEDVAA-------------ELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKE-------- 451
Query: 570 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ 629
D+ + K ++ +++ + LR DLER R L +I +REKLK K+Q+ +Q
Sbjct: 452 -DEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQ 510
Query: 630 L 630
+
Sbjct: 511 V 511
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 218 bits (555), Expect = 3e-56
Identities = 138/429 (32%), Positives = 201/429 (46%), Gaps = 55/429 (12%)
Query: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
Query: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
Query: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
Query: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
Query: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
Query: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
Query: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARLLVELIRKREKL 614
+ E+ N A +EQ L+ + LR DLER R L ++ +REK+
Sbjct: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKI 515
Query: 615 KRETIKVQQ 623
KR KVQ+
Sbjct: 516 KRSVCKVQE 524
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 206 bits (524), Expect = 1e-52
Identities = 142/461 (30%), Positives = 211/461 (45%), Gaps = 56/461 (12%)
Query: 176 LPEVVYRELEQ-DTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKT 234
+PE V R L + P A P+S E S + YD+DE D WL+++N K
Sbjct: 98 IPEPVVRILPPLEGPPAQASPSSTMLG-EGSQPDWPGGSRYDLDEIDAYWLELINSELKE 156
Query: 235 EGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALV----DEDAVCCICNDGECQNSNVI 290
+ + E +++ LE + + + DED VC +C E ++ N +
Sbjct: 157 MERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEM 216
Query: 291 LFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDG-RWA 349
+FCD CN+ VHQ CYG+ +P G WLCR C C LCP +GGA K T G +W
Sbjct: 217 VFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQ--PKCLLCPKRGGALKPTRSGTKWV 274
Query: 350 HVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAF 409
HV CALWIPEV +EPI I HIP +RW L+C +CK+ +G CIQC +C TAF
Sbjct: 275 HVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKE-CTGTCIQCSMPSCVTAF 333
Query: 410 HVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDED 469
HVTCA GL M+ + V+ ++C H+ G E +
Sbjct: 334 HVTCAFDHGLEMRT-------ILADNDEVKFKSFCQEHSDGG----------PRNEPTSE 376
Query: 470 EEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLT 529
E G EKV K + + ++++ L E +++ RL
Sbjct: 377 PTEPSQAGEDLEKVTLRKQRLQ-QLEEDFYELVEP-----------------AEVAERLD 418
Query: 530 IQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLK 589
+ + ++ YW LKR++ PLL D+V ++ + L +LK
Sbjct: 419 L--AEALVDFIYQYWKLKRKANANQPLL---------TPKTDEVDNLAQQEQDVLYRRLK 467
Query: 590 SWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQL 630
+ LR DLER R L ++ +RE+ K K+Q+ +Q+
Sbjct: 468 LFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQM 508
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 198 bits (504), Expect = 2e-50
Identities = 128/409 (31%), Positives = 187/409 (45%), Gaps = 55/409 (13%)
Query: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
Query: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
Query: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
Query: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
Query: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
Query: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
Query: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARL 603
+ E+ N A +EQ L+ + LR DLER +
Sbjct: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVMI 504
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 172 bits (437), Expect = 1e-42
Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)
Query: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN +EPI ++ +P R+ TCYIC +
Sbjct: 84 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445
+G +GAC+ C+K C AFHVTCAQ AGL + E NG +V+ YC
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
Query: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491
H + GS R +LS S + E E K + + K K K +
Sbjct: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 172 bits (437), Expect = 1e-42
Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)
Query: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN +EPI ++ +P R+ TCYIC +
Sbjct: 84 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445
+G +GAC+ C+K C AFHVTCAQ AGL + E NG +V+ YC
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
Query: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491
H + GS R +LS S + E E K + + K K K +
Sbjct: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 172 bits (435), Expect = 2e-42
Identities = 105/279 (37%), Positives = 151/279 (54%), Gaps = 54/279 (19%)
Query: 276 CCICNDGECQNSNVILFCD--MCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 66
Query: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN + +EPI ++++P R+ TCYIC++
Sbjct: 67 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPI-VLQYVPHDRFNKTCYICEE 125
Query: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGL-----YMKMEPVRETGANGTSFSVRK 440
+G SGAC+ C++ C AFHVTCAQ AGL ++++ V+ G FS K
Sbjct: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
Query: 441 TAYCDIHTPPG--------------------SARRLPALSHSEGEEDEDEEEDEGKGWSS 480
T+ H+ G S RR + S S +E + G
Sbjct: 186 TSR---HSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG----- 237
Query: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAP--VVSVPCIP 517
+ K K K R+K K +KR +P +++ P +P
Sbjct: 238 -QKKSRKDKERLKQKH------KKRPESPPSILTPPVVP 269
Score = 32.0 bits (71), Expect = 3.7
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 30/200 (15%)
Query: 846 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 905
SS + P P T S A + + P +S+TP + L KK+
Sbjct: 415 SSGRARAPSPGDYKSPHVTGSGASAGTHKRM-----PALSATPVPADETPETGLKEKKHK 469
Query: 906 KTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIM----------------SSLRQRK 949
+ PGRP +R + T G P P LP S +
Sbjct: 470 ASKRSRHGPGRPKGSRNKEGT----GGPAA-PSLPSAQLAGFTATAASPFSGGSLVSSGL 524
Query: 950 RGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSS--DS 1007
G S R S S S E P L A ++ P+ S + R CS P SSS
Sbjct: 525 GGLSSRTFGPSGSLPSLSLESPL--LGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGP 582
Query: 1008 ESSSSSSSSAASDRTSTTPS 1027
+S+ + S TST PS
Sbjct: 583 PGTSALPRLSRSPFTSTLPS 602
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 130 bits (326), Expect = 1e-29
Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422
ID + IP R KL C C+ +R SGACIQC C +FHVTCA AG+ M+
Sbjct: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 130 bits (326), Expect = 1e-29
Identities = 104/355 (29%), Positives = 155/355 (43%), Gaps = 56/355 (15%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKLTCYICK---QRGSGACIQCHKANCYTAFHVTCAQQAGLYMK 422
ID + IP R KL C C+ +R SGACIQC C +FHVTCA AG+ M+
Sbjct: 796 ID-VGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLME 849
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 126 bits (316), Expect = 1e-28
Identities = 62/137 (45%), Positives = 80/137 (58%), Gaps = 6/137 (4%)
Query: 290 ILFCDMCNLAVHQECYGV-PYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRW 348
++ C C L VH CYG+ P + W C RC A +C LC +GGA + T D RW
Sbjct: 757 LIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTA-ECCLCNLRGGALQMTTDRRW 815
Query: 349 AHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQR---GSGACIQCHKANC 405
HV+CA+ +PE F N + P+D I IP RWKL C C++R SGACIQC +C
Sbjct: 816 IHVICAIAVPEARFLNVIERHPVD-ISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHC 874
Query: 406 YTAFHVTCAQQAGLYMK 422
T+FHVTCA AG+ M+
Sbjct: 875 STSFHVTCAHAAGVLME 891
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 121 bits (303), Expect = 5e-27
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 6/144 (4%)
Query: 283 ECQNSNVILFCDMCNLAVHQECYGVPYIPEGQ-WLCRRCLQSPSRAVDCALCPNKGGAFK 341
E +++++ C C++ VH CYGVP + W+C RC + + DC LC +GGA +
Sbjct: 728 EEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQ 786
Query: 342 QTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICK---QRGSGACI 398
+ +D RW HV CA+ I E F N P+D + IP R+KL C CK +R +G C+
Sbjct: 787 RANDDRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
Query: 399 QCHKANCYTAFHVTCAQQAGLYMK 422
QC C TAFHV+CAQ AG+ M+
Sbjct: 846 QCSHGRCPTAFHVSCAQAAGVMMQ 869
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 114 bits (286), Expect = 4e-25
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 20/166 (12%)
Query: 270 VDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEG-----------QWLCR 318
+D +CC+C ++++ I+ CD C + VH+ CYGV + W C
Sbjct: 316 MDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCD 375
Query: 319 --RCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEH 376
+C SPS C LCPN+ G FK+TD GRW H+VCAL++P V F + L P+ E
Sbjct: 376 ACKCGVSPS----CELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEM 431
Query: 377 IPPARWKLTCYICKQ---RGSGACIQCHKANCYTAFHVTCAQQAGL 419
C C+ +G CI C C FHVTCAQ+ GL
Sbjct: 432 NYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGL 477
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 114 bits (286), Expect = 4e-25
Identities = 60/166 (36%), Positives = 82/166 (49%), Gaps = 20/166 (12%)
Query: 270 VDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEG-----------QWLCR 318
+D +CC+C ++++ I+ CD C + VH+ CYGV + W C
Sbjct: 316 MDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCD 375
Query: 319 --RCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEH 376
+C SPS C LCPN+ G FK+TD GRW H+VCAL++P V F + L P+ E
Sbjct: 376 ACKCGVSPS----CELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEM 431
Query: 377 IPPARWKLTCYICKQ---RGSGACIQCHKANCYTAFHVTCAQQAGL 419
C C+ +G CI C C FHVTCAQ+ GL
Sbjct: 432 NYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGL 477
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 90.5 bits (223), Expect = 9e-18
Identities = 84/314 (26%), Positives = 130/314 (41%), Gaps = 53/314 (16%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 541 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 600
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 601 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 659
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 660 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 698
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 699 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 737
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 738 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 795
Query: 371 IDSIEHIPPARWKL 384
ID + IP R KL
Sbjct: 796 ID-VGRIPLQRLKL 808
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 90.5 bits (223), Expect = 9e-18
Identities = 84/314 (26%), Positives = 130/314 (41%), Gaps = 53/314 (16%)
Query: 78 PSEVSQSPGRE-----VMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPEN 132
P E+ P E V S A+ + + R + +V + + EE PE
Sbjct: 563 PGEIPAVPSGERNSFKVPSIAEGENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEV 622
Query: 133 GSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAP 192
S +E E + K H + K + +N + + + + PD+
Sbjct: 623 LSIEEEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDS- 681
Query: 193 PRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRL 252
S EE D E +DE ++ KT+ + IP+ F Y + +
Sbjct: 682 ------------SNEENDARWETKLDE-------VVTSEGKTKPL--IPEMCFIYSEENI 720
Query: 253 EKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPY--I 310
E PNA ++ED +++++ C C + VH CYG+P I
Sbjct: 721 EYSP---------PNAFLEEDG------------TSLLISCAKCCVRVHASCYGIPSHEI 759
Query: 311 PEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEP 370
+G WLC RC ++ A +C LC +GGA KQT + +WAHV+CA+ +PEV F N
Sbjct: 760 CDG-WLCARCKRNAWTA-ECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQ 817
Query: 371 IDSIEHIPPARWKL 384
ID + IP R KL
Sbjct: 818 ID-VGRIPLQRLKL 830
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 82.0 bits (201), Expect = 3e-15
Identities = 83/293 (28%), Positives = 135/293 (46%), Gaps = 24/293 (8%)
Query: 574 GRDSEDKNWALKEQLKSWQRLRHDLERARLL-----VELIRKREKLKRETIKVQQIAMEM 628
G + K +KE K R R + E + L V L EK ++ Q+ E+
Sbjct: 75 GEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKPLTSSLAKQE---EV 131
Query: 629 QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNL 688
+ TP L + + QLQ KD FS PV T+ P Y IK PMDF TMK+ +
Sbjct: 132 EQTPLQEALNQLMRQLQRKDPSAFFSFPV-----TDFI-APGYSMIIKHPMDFSTMKEKI 185
Query: 689 EAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGID 748
+ Y + ++ +++F L+ +N + YN +TI+Y+AA +L G +L Q R Q+ K ID
Sbjct: 186 KNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSID 245
Query: 749 FETGMHIPHSLA-GDEATHHTEDAA--EEERLVLLENQKHL---PVEEQLKLLLERL-DE 801
F + G + + ED + ER + + H P +E K + L D+
Sbjct: 246 FMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKDMLEDK 305
Query: 802 VNASKQSVGRSRRAKMIKKEMTALRRKLAH-QRETGRDGPERHGPSSRGSLTP 853
++ + + +++K+ L R+L + Q E R P+ G ++ G L P
Sbjct: 306 FKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPD--GTTTLGLLHP 356
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 68.6 bits (166), Expect = 4e-11
Identities = 43/121 (35%), Positives = 60/121 (49%), Gaps = 11/121 (9%)
Query: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEV-PDYLDHIKKPMDFFTMK 685
E + TP LL L QLQ KD F+ PV D + P Y IK PMDF TMK
Sbjct: 135 ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVT-------DAIAPGYSMIIKHPMDFGTMK 187
Query: 686 QNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKM 745
+ A Y + +F+ DF L+ N + YN DT++Y+ A ++ G + +QA +
Sbjct: 188 DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAG---FKMMSKQAALL 244
Query: 746 G 746
G
Sbjct: 245 G 245
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 67.0 bits (162), Expect = 1e-10
Identities = 94/392 (23%), Positives = 162/392 (41%), Gaps = 44/392 (11%)
Query: 667 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 726
E+ DY D IK PMD T+K+ ++ Y + F D L+ SNC KYN D A +
Sbjct: 344 ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK 403
Query: 727 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA--------AEEERLV 778
L Q +R A+ E + P G E++ +E++ +EEER
Sbjct: 404 L--QDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERAT 461
Query: 779 -LLENQKHL-PVEEQLKLLLER-LDEVNASKQSVGRSRRAKMIKKE-----MTALRRKLA 830
L E Q+ L V EQL L + +++ K+ + ++ K +KE + A K A
Sbjct: 462 RLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKA 521
Query: 831 HQRETGRDGPERHGPSSR-GSLTPHPAACDKDGQTDSAAEESSSQE--------TSKGLG 881
+ ++ P+ + S T K G+ SA+ +S +E + L
Sbjct: 522 KVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLS 581
Query: 882 PNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPI 941
+++ P ++GR ++ S++ P R P + T + + + +
Sbjct: 582 LDINRLPGEKLGRVVHIIQSRE------PSLRDSNPDEIEIDFETLK--PTTLRELERYV 633
Query: 942 MSSLRQRKR------GRSPRPSSSSDSDSDKSTE-DPPMDLPANGFSGGNQPVKKS--FL 992
S L++++R G+ S + +K E + + + S +P +K
Sbjct: 634 KSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGS 693
Query: 993 VYRNDCSLPRSSSDSESSSSSSSSAASDRTST 1024
S SSS SES SSSSS ++SD + +
Sbjct: 694 APSGGPSRLSSSSSSESGSSSSSGSSSDSSDS 725
Score = 42.7 bits (99), Expect = 0.002
Identities = 20/47 (42%), Positives = 28/47 (59%)
Query: 668 VPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 714
+PDY IK PMD T+K+ LE Y + + +DFN + +NC YN
Sbjct: 70 LPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
Score = 32.3 bits (72), Expect = 2.8
Identities = 40/152 (26%), Positives = 58/152 (38%), Gaps = 22/152 (14%)
Query: 845 PSSRGSLTPHPAACDKDGQTDSAAEESSSQETS-KGLGPNMSSTP---AHEVGRRTSVLF 900
P+ +G A G AA S S T + + P +S TP A V T+ +
Sbjct: 150 PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
Query: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSS- 959
S P A PP PP TP PV PP P++ +++ + P++S
Sbjct: 210 SVPVPPAAAPP-----PPA------TPI---VPVVPPTPPVVKKKGVKRKADTTTPTTSA 255
Query: 960 ---SDSDSDKSTEDPPMDLPANGFSGGNQPVK 988
S S+S DP G +P+K
Sbjct: 256 ITASRSESPPPLSDPKQAKVVARRESGGRPIK 287
Score = 31.2 bits (69), Expect = 6.3
Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 52 PPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRIS 111
P P KG +S ++++S S S S S A+ Q
Sbjct: 423 PALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQ--------------- 467
Query: 112 IFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRK 158
+ L V E A +AP N K+ + K K K KEK K
Sbjct: 468 --EQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHK 512
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 65.9 bits (159), Expect = 2e-10
Identities = 88/385 (22%), Positives = 147/385 (38%), Gaps = 62/385 (16%)
Query: 670 DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLRE 729
DY D IK PMD T+K LEA Y + +F D L+ SNC KYN D A +L++
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 730 QGGAVLRQARRQAEKMGIDFETGMHIP-------------HSLAGDEATHHTEDAAEEER 776
+ + E+ + + P S + ++ T+D+ EE
Sbjct: 449 VFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERA 508
Query: 777 LVLLENQKHL-PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRET 835
L E Q+ L V EQL L + K+ + ++ + K++ K + +E
Sbjct: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
Query: 836 GRDGPERHGPSSRGSLTPHPAAC-DKDGQTDSAAEESS----SQETSKGLGPNMSSTPAH 890
+++ S+ PA K T + EE S E + L +++ P
Sbjct: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
Query: 891 EVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKR 950
++GR ++ S++ P P E + S + + + S LR++++
Sbjct: 629 KLGRVVHIIQSRE-------PSLKNSNPDEIEIDF-ETLKPSTLRELERYVTSCLRKKRK 680
Query: 951 GRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESS 1010
++ + + S K GF SSS+SESS
Sbjct: 681 PQAEKVDVIAGSSKMK------------GF----------------------SSSESESS 706
Query: 1011 SSSSSSAASD-RTSTTPSKQGRGKP 1034
S SSSS + D T P + +G P
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHP 731
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 636 LLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLN 695
LLR L+ L + F +PV ++ +PDY IK PMD T+K+ LE Y N
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLN----LPDYYKIIKTPMDMGTIKKRLENNYYWN 121
Query: 696 FDDFEEDFNLIVSNCLKYN 714
+ +DFN + +NC YN
Sbjct: 122 AQECIQDFNTMFTNCYIYN 140
Score = 39.3 bits (90), Expect = 0.023
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 124 EAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRE 183
E+ + + S+ E++ET A PKS K + + + +HHHHH +P+
Sbjct: 702 ESESSSESSSSDSEDSETEMA-PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPP 760
Query: 184 LEQDTPDAPPR 194
+Q P PP+
Sbjct: 761 PQQPPPPPPPQ 771
>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
Length = 1458
Score = 64.7 bits (156), Expect = 5e-10
Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 627 EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQ 686
E L + LR ++L NIFS+PV +++EV DYL+ IK+PMD T+
Sbjct: 957 ENTLRELRLFLRDVTKRLATDKRFNIFSKPV------DIEEVSDYLEVIKEPMDLSTVIT 1010
Query: 687 NLEAYRYLNFDDFEEDFNLIVSNCLKYN----------------AKDTIFYRAAVRLREQ 730
++ + YL DF +D +LI SN L+YN KDT A L +
Sbjct: 1011 KIDKHNYLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPE 1070
Query: 731 GGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA 771
+ + + K G+ + PHS + E+A
Sbjct: 1071 FNKLCEEIKEARIKRGLSVTSEQINPHSTGARKTETRVEEA 1111
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 1e-09
Identities = 107/433 (24%), Positives = 159/433 (36%), Gaps = 97/433 (22%)
Query: 670 DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLRE 729
DY D IK PMD T+K+ +E Y + +F D L+ SNC KYN D A +L
Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL-- 442
Query: 730 QGGAVLRQARRQAEKM---GIDFETGMHIPHSLA-----------GDEATHHTEDAAEEE 775
Q R A+ E + + T M P LA E++ E+ +EE
Sbjct: 443 QDVFEFRYAKMPDEPLEPGPLPVSTAM--PPGLAKSSSESSSEESSSESSSEEEEEEDEE 500
Query: 776 RLVLLENQKHLPVEEQLKLLLERLDEVNA--------SKQSVGRSRRAKMIKKEMTALRR 827
E++ EE+ L E +++ A S+ + + +R K KKE R+
Sbjct: 501 DEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKR-KREKKEKKKKRK 559
Query: 828 KLAHQRETGRD------------------------------GPERHGPSSRGSLTPHPAA 857
H+ G D GP GPS GS T P
Sbjct: 560 AEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSG-GSGTKLPKK 618
Query: 858 CDKDGQT------DSAAEESS---SQETSKGLGPNMSSTPAHEVGRRTSVLFSKK----- 903
K DS EE S S + + L +++ P ++GR ++ +++
Sbjct: 619 ATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRD 678
Query: 904 -NPKTAGPPKRPGRPPKNRESQ-----------MTPSHGGSPVGPPQLPIMSSLRQRKRG 951
NP+ +P RE + P PVG + + ++
Sbjct: 679 SNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELEK 738
Query: 952 RSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSS 1011
R S + ST+ PP S Q V S L SSS S+SSS
Sbjct: 739 RLQDVSGQLN-----STKKPPKKANEKTESSSAQQVAVS--------RLSASSSSSDSSS 785
Query: 1012 SSSSSAASDRTST 1024
SSSSS++SD + +
Sbjct: 786 SSSSSSSSDTSDS 798
Score = 42.0 bits (97), Expect = 0.004
Identities = 20/47 (42%), Positives = 28/47 (59%)
Query: 668 VPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 714
+PDY IK+PMD T+K+ LE Y + +DFN + +NC YN
Sbjct: 110 LPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 1e-09
Identities = 107/433 (24%), Positives = 159/433 (36%), Gaps = 97/433 (22%)
Query: 670 DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLRE 729
DY D IK PMD T+K+ +E Y + +F D L+ SNC KYN D A +L
Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKL-- 442
Query: 730 QGGAVLRQARRQAEKM---GIDFETGMHIPHSLA-----------GDEATHHTEDAAEEE 775
Q R A+ E + + T M P LA E++ E+ +EE
Sbjct: 443 QDVFEFRYAKMPDEPLEPGPLPVSTAM--PPGLAKSSSESSSEESSSESSSEEEEEEDEE 500
Query: 776 RLVLLENQKHLPVEEQLKLLLERLDEVNA--------SKQSVGRSRRAKMIKKEMTALRR 827
E++ EE+ L E +++ A S+ + + +R K KKE R+
Sbjct: 501 DEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKR-KREKKEKKKKRK 559
Query: 828 KLAHQRETGRD------------------------------GPERHGPSSRGSLTPHPAA 857
H+ G D GP GPS GS T P
Sbjct: 560 AEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSG-GSGTKLPKK 618
Query: 858 CDKDGQT------DSAAEESS---SQETSKGLGPNMSSTPAHEVGRRTSVLFSKK----- 903
K DS EE S S + + L +++ P ++GR ++ +++
Sbjct: 619 ATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRD 678
Query: 904 -NPKTAGPPKRPGRPPKNRESQ-----------MTPSHGGSPVGPPQLPIMSSLRQRKRG 951
NP+ +P RE + P PVG + + ++
Sbjct: 679 SNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELEK 738
Query: 952 RSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSS 1011
R S + ST+ PP S Q V S L SSS S+SSS
Sbjct: 739 RLQDVSGQLN-----STKKPPKKANEKTESSSAQQVAVS--------RLSASSSSSDSSS 785
Query: 1012 SSSSSAASDRTST 1024
SSSSS++SD + +
Sbjct: 786 SSSSSSSSDTSDS 798
Score = 42.0 bits (97), Expect = 0.004
Identities = 20/47 (42%), Positives = 28/47 (59%)
Query: 668 VPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 714
+PDY IK+PMD T+K+ LE Y + +DFN + +NC YN
Sbjct: 110 LPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/328 (22%), Positives = 126/328 (38%), Gaps = 27/328 (8%)
Query: 670 DYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLRE 729
DY D IK PMD T+K LEA Y + +F D L+ SNC KYN D A +L++
Sbjct: 389 DYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD 448
Query: 730 QGGAVLRQARRQAEKMGIDFETGMHIP-------------HSLAGDEATHHTEDAAEEER 776
+ + E+ + + P S + ++ T+D+ EE
Sbjct: 449 VFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERA 508
Query: 777 LVLLENQKHL-PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRET 835
L E Q+ L V EQL L + K+ + ++ + K++ K + +E
Sbjct: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
Query: 836 GRDGPERHGPSSRGSLTPHPAAC-DKDGQTDSAAEESS----SQETSKGLGPNMSSTPAH 890
+++ S+ PA K T + EE S E + L +++ P
Sbjct: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
Query: 891 EVGRRTSVLFSKK------NPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSS 944
++GR ++ S++ NP +P RE + + PQ +
Sbjct: 629 KLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDV 688
Query: 945 L--RQRKRGRSPRPSSSSDSDSDKSTED 970
+ + +G S S SS S +ED
Sbjct: 689 IAGSSKMKGFSSSESESSSESSSSDSED 716
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 636 LLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLN 695
LLR L+ L + F +PV ++ +PDY IK PMD T+K+ LE Y N
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKLN----LPDYYKIIKTPMDMGTIKKRLENNYYWN 121
Query: 696 FDDFEEDFNLIVSNCLKYN 714
+ +DFN + +NC YN
Sbjct: 122 AQECIQDFNTMFTNCYIYN 140
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 60.5 bits (145), Expect = 1e-08
Identities = 42/141 (29%), Positives = 67/141 (47%), Gaps = 16/141 (11%)
Query: 614 LKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVTELDEVPDYLD 673
L E +K + E I LR +L +F++PV + DEVPDY+
Sbjct: 970 LTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPV------DPDEVPDYVT 1023
Query: 674 HIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK----DTIFYRAAVRLRE 729
IK+PMD ++ ++ ++YL D+ D +LI SN L+YN D + A LR+
Sbjct: 1024 VIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRD 1083
Query: 730 QGGAVLRQARRQAEKMGIDFE 750
A+++ E++ DFE
Sbjct: 1084 TAYAIIK------EELDEDFE 1098
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 56.2 bits (134), Expect = 2e-07
Identities = 79/323 (24%), Positives = 132/323 (40%), Gaps = 28/323 (8%)
Query: 769 EDAAEEER----LVLLENQKHLPVEEQ---LKLLLERLDEVNAS-KQSVGRSRRAKMIKK 820
E+A EEE +V + +K EEQ +++ +E EV S KQ + + +
Sbjct: 332 EEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLE 391
Query: 821 EMTALRRKLAHQRETGRDGPERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGL 880
+ ++ +A Q + E S+ P K+ + + E +E K L
Sbjct: 392 MVENVKHVIADQEVMETNRVE--------SVEPSENEASKELEPEMEFEIEPDKEC-KSL 442
Query: 881 GPNMSSTPAHEVGRRTSVLFSKKN---PKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPP 937
P + A ++ + + K++ P+ P+ +P +SQ P P P
Sbjct: 443 SPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQP 502
Query: 938 Q---LPIMSSLRQ--RKRGRSPRPSSSSDSDSDKSTEDP--PMDLPANGFSGGNQPVKKS 990
+ L ++ Q +++G +S K TE P P+ + +S
Sbjct: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
Query: 991 FLVYRNDCSLPRS-SSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRGTFPEDSSEDT 1049
RN S RS SS S SSSSSS+S++S +S++ S R S S T S + +
Sbjct: 563 RGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSS 622
Query: 1050 SGTENEAYSVGTGRGVGHSMVRK 1072
S T + + S RG GH+ RK
Sbjct: 623 SSTSSSSESRSRSRGRGHNRDRK 645
Score = 32.7 bits (73), Expect = 2.2
Identities = 42/190 (22%), Positives = 66/190 (34%), Gaps = 20/190 (10%)
Query: 786 LPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGP 845
+PVE L + E + +S GR+R K + R + +
Sbjct: 540 VPVEPVLTVHPESKSKTKTRSRSRGRARN----KTSKSRSRSSSSSSSSSSSTSSSSGSS 595
Query: 846 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 905
SS GS + ++ + S++ +SSS +S + S H R+ +K
Sbjct: 596 SSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRR 655
Query: 906 KTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKR-----GRSPRPSSSS 960
T+G E S GGS +S RKR RS + SS S
Sbjct: 656 DTSG-----------LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
Query: 961 DSDSDKSTED 970
+ D +D
Sbjct: 705 ERDRKSDRKD 714
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,404,131
Number of Sequences: 37866
Number of extensions: 3048832
Number of successful extensions: 23325
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 729
Number of HSP's that attempted gapping in prelim test: 17441
Number of HSP's gapped (non-prelim): 5086
length of query: 1220
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1106
effective length of database: 13,930,794
effective search space: 15407458164
effective search space used: 15407458164
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.