BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|51100974 myosin ID [Homo sapiens] (1006 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|51100974 myosin ID [Homo sapiens] 2017 0.0 gi|239582755 myosin IG [Homo sapiens] 1241 0.0 gi|44889481 myosin IB isoform 2 [Homo sapiens] 717 0.0 gi|194328685 myosin IB isoform 1 [Homo sapiens] 705 0.0 gi|240120050 myosin IB isoform 1 [Homo sapiens] 705 0.0 gi|124494247 myosin IC isoform b [Homo sapiens] 697 0.0 gi|124494238 myosin IC isoform a [Homo sapiens] 697 0.0 gi|124494240 myosin IC isoform c [Homo sapiens] 697 0.0 gi|4885503 myosin IA [Homo sapiens] 690 0.0 gi|254028267 myosin 1H [Homo sapiens] 667 0.0 gi|55956916 myosin IE [Homo sapiens] 564 e-160 gi|27544941 myosin IF [Homo sapiens] 539 e-153 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 478 e-134 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 478 e-134 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 478 e-134 gi|215982794 myosin VA isoform 2 [Homo sapiens] 471 e-132 gi|215982791 myosin VA isoform 1 [Homo sapiens] 471 e-132 gi|153945715 myosin VC [Homo sapiens] 469 e-132 gi|118402590 myosin XV [Homo sapiens] 459 e-129 gi|122937512 myosin VIIB [Homo sapiens] 451 e-126 gi|122937345 myosin VB [Homo sapiens] 450 e-126 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 439 e-123 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 439 e-123 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 439 e-123 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 435 e-122 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 435 e-122 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 432 e-121 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 432 e-121 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 432 e-121 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 430 e-120 >gi|51100974 myosin ID [Homo sapiens] Length = 1006 Score = 2017 bits (5226), Expect = 0.0 Identities = 1006/1006 (100%), Positives = 1006/1006 (100%) Query: 1 MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60 MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR Sbjct: 1 MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60 Query: 61 DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120 DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA Sbjct: 61 DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120 Query: 121 AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180 AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH Sbjct: 121 AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180 Query: 181 INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240 INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS Sbjct: 181 INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240 Query: 241 INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII 300 INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII Sbjct: 241 INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII 300 Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN Sbjct: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ Sbjct: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG Sbjct: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480 Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN Sbjct: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI Sbjct: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK Sbjct: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 Query: 661 KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR 720 KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR Sbjct: 661 KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR 720 Query: 721 TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF 780 TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF Sbjct: 721 TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF 780 Query: 781 NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT 840 NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT Sbjct: 781 NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT 840 Query: 841 FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP 900 FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP Sbjct: 841 FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP 900 Query: 901 LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL 960 LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL Sbjct: 901 LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL 960 Query: 961 QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN 1006 QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN Sbjct: 961 QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN 1006 >gi|239582755 myosin IG [Homo sapiens] Length = 1018 Score = 1241 bits (3210), Expect = 0.0 Identities = 611/1016 (60%), Positives = 783/1016 (77%), Gaps = 12/1016 (1%) Query: 1 MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60 M ++E E+GK DFVL+D V+M +FM NL+LRFEKGRIYT+IGEV+VSVNPY+ L +YG Sbjct: 1 MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP 60 Query: 61 DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120 + I +Y+GRELYERPPHL+A+A+AAYKAMK RS+DTCIVISGESGAGKTEASK+IMQYIA Sbjct: 61 EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA 120 Query: 121 AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180 A+TNPSQRAEVERVK++LLKS CVLEAFGNA+TNRN NSSRFGKYMDINFDFKGDPIGGH Sbjct: 121 AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180 Query: 181 INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240 I++YLLEKSRV+ Q GER+FH+FYQLL+G ++ L LHL+++ + YN+ H GA L + Sbjct: 181 IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240 Query: 241 INDAAE-----FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENG- 294 ++ A + + V +AM+VIGF PEE+++V++ILAAILHLGN++FV + L + G Sbjct: 241 VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300 Query: 295 -----KVVSIIAELLSTKTDMVEKALLYRTVATG-RDIIDKQHTEQEASYGRDAFAKAIY 348 +V +AEL +T D+V ++LL RTVA+G R++I+K HT EASY RDA AKA+Y Sbjct: 301 AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY 360 Query: 349 ERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQ 408 +RLF W+V RIN ++E + D GK+TVIGVLDIYGFE+F NSFEQFCINYCNEKLQ Sbjct: 361 QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 420 Query: 409 QLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTD 468 QLFIQL+LKQEQEEY+REGI W+ ++YFNN IVDLVE+ H+GI+A+LD+AC + G +TD Sbjct: 421 QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD 480 Query: 469 EMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF 528 +FL+ L+ H H++SR+LC +DK +EF RDFRI+HYAGDV YSV GFIDKN+D LF Sbjct: 481 RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540 Query: 529 QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVR 588 QDFKRL+YNS++P L+ MWP+G+ ITEVTKRPLTA TLFKNSM+ALV+NLASKEP+YVR Sbjct: 541 QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600 Query: 589 CIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWP 648 CIKPN+ K D+ CRHQV YLGLLENVRVRRAGFA RQ Y +FL RYKM E+TWP Sbjct: 601 CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660 Query: 649 NHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV 708 NH L SDK AV L+E+ G Q DVA+G +K+FIR+PRTL TLE+ RA+++ IVL LQK Sbjct: 661 NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720 Query: 709 WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKV 768 WRGTLAR R +R +A TI+R++RR+KV++++ E+ RRF + YG+ + WP PP V Sbjct: 721 WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV 780 Query: 769 LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYL 828 L+ F++ +F RWRA QL+K+IP SD+PQ++AKVAA+ L+G R D G +RAW +YL Sbjct: 781 LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL 840 Query: 829 ASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD 888 +S D P S F L+ KD + VLFS HVRKVNRF K+ +RA+ +TD+HLYK+D Sbjct: 841 SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD 900 Query: 889 PTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGV 948 P +QY+VM+ +PL +TGLSV++G DQLVV H + DL+VCL +P ++R+GELVGV Sbjct: 901 PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV 960 Query: 949 LVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVP 1004 L H + E R L+V V++ + S G + +SVE R QP+PDF R F L P Sbjct: 961 LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWP 1016 >gi|44889481 myosin IB isoform 2 [Homo sapiens] Length = 1078 Score = 717 bits (1852), Expect = 0.0 Identities = 413/1006 (41%), Positives = 584/1006 (58%), Gaps = 112/1006 (11%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL++ ++ F+ NL+ RF+ IYT+IG VV+SVNPY+ L IY + +E+Y+ R Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+ A Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 EV +VK LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 RV+ Q GER+FH FYQLL G SE++L L L++ S YNY+ + + + ++DAA FR Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253 Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304 V +AM+++GF E ++V ++AA+L LGN++F + D I++ + I EL Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 ++E+A +RTV ++ + +A Y RDA AK +Y RLF W+V RIN+ I+ Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 + T + K V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484 RE I W HIDYFNN II DL+E GI+A+LD+ C+ G VTDE FLE LN H H Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488 Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537 F SR K F D FRI+HYAG V+Y V GF+DKN D L++D + M+ Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544 Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597 +S+ ++K+++PEG + + KRP TA + FK S+ L+ NL +K P Y+RCIKPNDKK+ Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603 Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657 IF++ HQ+ YLGLLENVRVRRAG+AFRQ YE L RYKM+ + TWP+ P+ + Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662 Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLAR- 715 V+ L ++ ++G++KIFIR PRTLF LE+LR Q L + +QK++RG R Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722 Query: 716 ----------------------MRYKRTK-AALTIIRYYRRYKVKSYIHE---------- 742 RY++TK +AL I Y R +K + + E Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782 Query: 743 ---VARRFHGVKTMRDYGKHVK------------------------------------WP 763 +A +HG + R+Y K + WP Sbjct: 783 VTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWP 842 Query: 764 SPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRA--DLGLQ 820 S P + L + L+ IF+ WR + K+ A E+ K ++A + Sbjct: 843 SRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVG 902 Query: 821 RAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVT 880 + ++G YL + P +LK + ++ + V K+NR + IF+ Sbjct: 903 QPFQGAYLEINKN---------PKYKKLKDAIE-EKIIIAEVVNKINRANGKSTSRIFLL 952 Query: 881 DRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKD 926 + + K ++ +PL ++T +S+S+ D H K+ + Sbjct: 953 TNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSE 998 >gi|194328685 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 705 bits (1820), Expect = 0.0 Identities = 376/792 (47%), Positives = 515/792 (65%), Gaps = 27/792 (3%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL++ ++ F+ NL+ RF+ IYT+IG VV+SVNPY+ L IY + +E+Y+ R Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+ A Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 EV +VK LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 RV+ Q GER+FH FYQLL G SE++L L L++ S YNY+ + + + ++DAA FR Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253 Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304 V +AM+++GF E ++V ++AA+L LGN++F + D I++ + I EL Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 ++E+A +RTV ++ + +A Y RDA AK +Y RLF W+V RIN+ I+ Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 + T + K V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484 RE I W HIDYFNN II DL+E GI+A+LD+ C+ G VTDE FLE LN H H Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488 Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537 F SR K F D FRI+HYAG V+Y V GF+DKN D L++D + M+ Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544 Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597 +S+ ++K+++PEG + + KRP TA + FK S+ L+ NL +K P Y+RCIKPNDKK+ Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603 Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657 IF++ HQ+ YLGLLENVRVRRAG+AFRQ YE L RYKM+ + TWP+ P+ + Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662 Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARM 716 V+ L ++ ++G++KIFIR PRTLF LE+LR Q L + +QK++RG R Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722 Query: 717 RY-KRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEA 775 + K+ + I +YRRY + + +++ K K K +R +EA Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782 Query: 776 LQTIFNRWRASQ 787 + TI W +Q Sbjct: 783 VTTIAAYWHGTQ 794 Score = 42.7 bits (99), Expect = 0.002 Identities = 47/242 (19%), Positives = 96/242 (39%), Gaps = 24/242 (9%) Query: 691 EELRAQMLIRIVLFLQKVWRGTLARMRYK---RTKAALTIIRYYRRYKVKSYIHEVARRF 747 EE R + + ++ W G R Y+ R A I + + V+ Y E+ + Sbjct: 833 EEARRKHAVAVIW---AYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKM 889 Query: 748 HGVKTMRDYGKHVKWPSPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAA 806 + + WPS P + L + L+ IF+ WR + K+ A Sbjct: 890 PSLSPIDK-----NWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEA 944 Query: 807 VEMLKGQRA--DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVR 864 E+ K ++A + + ++G YL + + + + ++ K ++ + V Sbjct: 945 SELFKDKKALYPSSVGQPFQGAYLEINKNPK-----YKKLKDAIEEK-----IIIAEVVN 994 Query: 865 KVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDN 924 K+NR + IF+ + + K ++ +PL ++T +S+S+ D H K+ Sbjct: 995 KINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEG 1054 Query: 925 KD 926 + Sbjct: 1055 SE 1056 >gi|240120050 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 705 bits (1820), Expect = 0.0 Identities = 376/792 (47%), Positives = 515/792 (65%), Gaps = 27/792 (3%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL++ ++ F+ NL+ RF+ IYT+IG VV+SVNPY+ L IY + +E+Y+ R Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+ A Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 EV +VK LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 RV+ Q GER+FH FYQLL G SE++L L L++ S YNY+ + + + ++DAA FR Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253 Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304 V +AM+++GF E ++V ++AA+L LGN++F + D I++ + I EL Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 ++E+A +RTV ++ + +A Y RDA AK +Y RLF W+V RIN+ I+ Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 + T + K V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484 RE I W HIDYFNN II DL+E GI+A+LD+ C+ G VTDE FLE LN H H Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488 Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537 F SR K F D FRI+HYAG V+Y V GF+DKN D L++D + M+ Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544 Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597 +S+ ++K+++PEG + + KRP TA + FK S+ L+ NL +K P Y+RCIKPNDKK+ Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603 Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657 IF++ HQ+ YLGLLENVRVRRAG+AFRQ YE L RYKM+ + TWP+ P+ + Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662 Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARM 716 V+ L ++ ++G++KIFIR PRTLF LE+LR Q L + +QK++RG R Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722 Query: 717 RY-KRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEA 775 + K+ + I +YRRY + + +++ K K K +R +EA Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782 Query: 776 LQTIFNRWRASQ 787 + TI W +Q Sbjct: 783 VTTIAAYWHGTQ 794 Score = 42.7 bits (99), Expect = 0.002 Identities = 47/242 (19%), Positives = 96/242 (39%), Gaps = 24/242 (9%) Query: 691 EELRAQMLIRIVLFLQKVWRGTLARMRYK---RTKAALTIIRYYRRYKVKSYIHEVARRF 747 EE R + + ++ W G R Y+ R A I + + V+ Y E+ + Sbjct: 833 EEARRKHAVAVIW---AYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKM 889 Query: 748 HGVKTMRDYGKHVKWPSPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAA 806 + + WPS P + L + L+ IF+ WR + K+ A Sbjct: 890 PSLSPIDK-----NWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEA 944 Query: 807 VEMLKGQRA--DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVR 864 E+ K ++A + + ++G YL + + + + ++ K ++ + V Sbjct: 945 SELFKDKKALYPSSVGQPFQGAYLEINKNPK-----YKKLKDAIEEK-----IIIAEVVN 994 Query: 865 KVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDN 924 K+NR + IF+ + + K ++ +PL ++T +S+S+ D H K+ Sbjct: 995 KINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEG 1054 Query: 925 KD 926 + Sbjct: 1055 SE 1056 >gi|124494247 myosin IC isoform b [Homo sapiens] Length = 1044 Score = 697 bits (1800), Expect = 0.0 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%) Query: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G DFVL++ S F+ NLR RF + IYT+IG V+VSVNPY+ L IY R +E+Y+G Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 YE PPHLFA+AD Y+A++ +D ++ISGESGAGKTEA+K ++Q+ A +R Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK Sbjct: 148 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 205 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 SRV+ Q GER+FH FYQLL+GG E+ LR L L+++ SY Y+ G K SSIND +++ Sbjct: 206 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 265 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306 +VV A+ VI F +E++ + I+A++LHLGN+ F + ++ + + + LLS Sbjct: 266 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 325 Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + + +AL +R + A G +++ + EQ A+Y RDA AKA+Y R F W+V +IN + Sbjct: 326 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 384 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 K+ ++ TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ Sbjct: 385 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 444 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485 EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+ G+ TD FLE L + H HF Sbjct: 445 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 504 Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 + KL R +FR+ HYAG+V YSV GF+DKN D LF++ K M +S NP++ Sbjct: 505 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 564 Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604 + +LS KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P FD+ Sbjct: 565 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 621 Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663 RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK + TWP P D AV L+ Sbjct: 622 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 679 Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699 G++ ++ G+TKIFIR P+TLF E E+R Q L Sbjct: 680 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 739 Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750 R + +Q WRGTL R + KR AA TI R R + ++ ++ + R + Sbjct: 740 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 799 Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807 R ++V WP+PP LR E L+ + + + +SI Q++ K A Sbjct: 800 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 859 Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867 E+ KG++ + ++ +++++ T + S + + ++ V K + Sbjct: 860 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 910 Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924 R K R + +T + ++ KV + I NLTG+SVS+ D L V H + DN Sbjct: 911 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 967 Query: 925 K 925 K Sbjct: 968 K 968 >gi|124494238 myosin IC isoform a [Homo sapiens] Length = 1063 Score = 697 bits (1800), Expect = 0.0 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%) Query: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G DFVL++ S F+ NLR RF + IYT+IG V+VSVNPY+ L IY R +E+Y+G Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 YE PPHLFA+AD Y+A++ +D ++ISGESGAGKTEA+K ++Q+ A +R Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK Sbjct: 167 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 SRV+ Q GER+FH FYQLL+GG E+ LR L L+++ SY Y+ G K SSIND +++ Sbjct: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 284 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306 +VV A+ VI F +E++ + I+A++LHLGN+ F + ++ + + + LLS Sbjct: 285 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 344 Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + + +AL +R + A G +++ + EQ A+Y RDA AKA+Y R F W+V +IN + Sbjct: 345 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 403 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 K+ ++ TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ Sbjct: 404 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 463 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485 EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+ G+ TD FLE L + H HF Sbjct: 464 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 523 Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 + KL R +FR+ HYAG+V YSV GF+DKN D LF++ K M +S NP++ Sbjct: 524 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 583 Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604 + +LS KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P FD+ Sbjct: 584 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 640 Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663 RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK + TWP P D AV L+ Sbjct: 641 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 698 Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699 G++ ++ G+TKIFIR P+TLF E E+R Q L Sbjct: 699 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 758 Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750 R + +Q WRGTL R + KR AA TI R R + ++ ++ + R + Sbjct: 759 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 818 Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807 R ++V WP+PP LR E L+ + + + +SI Q++ K A Sbjct: 819 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 878 Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867 E+ KG++ + ++ +++++ T + S + + ++ V K + Sbjct: 879 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 929 Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924 R K R + +T + ++ KV + I NLTG+SVS+ D L V H + DN Sbjct: 930 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 986 Query: 925 K 925 K Sbjct: 987 K 987 >gi|124494240 myosin IC isoform c [Homo sapiens] Length = 1028 Score = 697 bits (1800), Expect = 0.0 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%) Query: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G DFVL++ S F+ NLR RF + IYT+IG V+VSVNPY+ L IY R +E+Y+G Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 YE PPHLFA+AD Y+A++ +D ++ISGESGAGKTEA+K ++Q+ A +R Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK Sbjct: 132 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 189 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 SRV+ Q GER+FH FYQLL+GG E+ LR L L+++ SY Y+ G K SSIND +++ Sbjct: 190 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 249 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306 +VV A+ VI F +E++ + I+A++LHLGN+ F + ++ + + + LLS Sbjct: 250 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 309 Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + + +AL +R + A G +++ + EQ A+Y RDA AKA+Y R F W+V +IN + Sbjct: 310 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 368 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 K+ ++ TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ Sbjct: 369 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 428 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485 EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+ G+ TD FLE L + H HF Sbjct: 429 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 488 Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 + KL R +FR+ HYAG+V YSV GF+DKN D LF++ K M +S NP++ Sbjct: 489 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 548 Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604 + +LS KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P FD+ Sbjct: 549 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 605 Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663 RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK + TWP P D AV L+ Sbjct: 606 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 663 Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699 G++ ++ G+TKIFIR P+TLF E E+R Q L Sbjct: 664 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 723 Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750 R + +Q WRGTL R + KR AA TI R R + ++ ++ + R + Sbjct: 724 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 783 Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807 R ++V WP+PP LR E L+ + + + +SI Q++ K A Sbjct: 784 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 843 Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867 E+ KG++ + ++ +++++ T + S + + ++ V K + Sbjct: 844 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 894 Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924 R K R + +T + ++ KV + I NLTG+SVS+ D L V H + DN Sbjct: 895 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 951 Query: 925 K 925 K Sbjct: 952 K 952 >gi|4885503 myosin IA [Homo sapiens] Length = 1043 Score = 690 bits (1780), Expect = 0.0 Identities = 400/973 (41%), Positives = 575/973 (59%), Gaps = 81/973 (8%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL++ + + NL+LR+E IYT+IG VV+SVNPY+ L IYG + I +Y+ Sbjct: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PH++A+A+ AY++++ R +D CI+I+GESG+GKTEASK +M Y+AA+ + Sbjct: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE-- 126 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 +V VK LL+SN VLEAFGNAKT RN+NSSRFGKYMDI FDFKG P+GG I NYLLEKS Sbjct: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 R++ Q GER+FH FYQLL G EQ+L++L L++ + Y Y++ ++DA+ FR Sbjct: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASSFRA 246 Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNL----KFVVDG-DTPLIENGKVVSIIAELL 304 V AM VIGF EEI+ V ++ + +L LGN+ +F G I +G+ V I E++ Sbjct: 247 VQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMV 306 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 ++ VE+AL RT+ T ++ + +A Y RDA AK IY RLF WIV RIN+ I+ Sbjct: 307 GLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESIK 366 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 V I K V+GVLDIYGFEI ++NSFEQF INYCNEKLQQ+FI++ LK+EQEEY+ Sbjct: 367 V-----GIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYK 421 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484 REGIPW +DYF+N II L+E +GI+A+LD+ C+ G V+D FL LN KH H Sbjct: 422 REGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGH 481 Query: 485 FSSRKLCASDKILEFDRD-----FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539 + S+ + + ++D FRI HYAG V Y+V FIDKN D LF+D + M+ + Sbjct: 482 YESKVTQNAQR--QYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539 Query: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599 +P+L++++PEG + KRP TA FK+S+ L+ NL SK P Y+RCIKPN+ + Sbjct: 540 HPLLRSLFPEGNPKQASL-KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRG 598 Query: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659 F + Q YLGLLENVRVRRAG+A RQ Y FL RY+++S TWP H D+E V Sbjct: 599 QFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWP-HWNGGDREGV 657 Query: 660 KKLIERCGFQD-DVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718 +K++ ++A+GKTKIFIR+P+TLF LEE R L ++ +QK++RG R Y Sbjct: 658 EKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHY 717 Query: 719 KRTKAALTIIRYYRR--------YKVKSYIHEVARRFHGVKTMRDYGKHVK--------- 761 + + + +I + R K+K+ + + G K ++Y K+ + Sbjct: 718 QLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLAD 777 Query: 762 ---------------------------WPSPP-KVLRRFEEALQTIFNRWRASQLIKSIP 793 WP+ P K L + LQ +F +W+ + + Sbjct: 778 FIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLS 837 Query: 794 ASDLPQVRAKVAAVEMLKGQRADL--GLQRAWEGNYLASKPDTPQTSGTFVPVANELKRK 851 + +R K+ A E+ KG++A + + G+Y+ + + P +LK Sbjct: 838 PKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGN---------PKLQKLKGG 888 Query: 852 DKYMNVLFSCHVRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVS 910 ++ VL + V+KVNR + K R + +T H+ D TK+ + I L N+ G+SV+ Sbjct: 889 EE-GPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTD-TKKSQAKIVIGLDNVAGVSVT 946 Query: 911 NGKDQLVVFHTKD 923 + KD L H + Sbjct: 947 SLKDGLFSLHLSE 959 >gi|254028267 myosin 1H [Homo sapiens] Length = 1022 Score = 667 bits (1721), Expect = 0.0 Identities = 423/1048 (40%), Positives = 597/1048 (56%), Gaps = 107/1048 (10%) Query: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G DFVL+D S F+ NLR RF + IYT+IG ++VSVNPY+ L IY +E Y+G Sbjct: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 +E PPH++AIAD AY+ M + I+ISGESGAGKTEASK I++Y A +Q Sbjct: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 ++ R + LL SN VLEAFGNA+T RNDNSSRFGKYMDI FDF+G P+GGHI +YL+EK Sbjct: 132 LQIAR--DRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 SRV+ Q GER+FH FYQLL GG E+ L L L++ Y Y+ G K SSI+D ++ Sbjct: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGD-TPLIENGKVVSIIAELLST 306 + V++A VI F +++ ++ I+A++LHLGN+ F D I + + IA+LL Sbjct: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGV 309 Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366 ++ +AL +R + + + T + + Y RDA AKA+Y R F W+V +IN + K Sbjct: 310 HPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNK 369 Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426 ++ + TVIG+LDIYGFE+FD N FEQFCINYCNEKLQQL I+ LK EQ EY+ E Sbjct: 370 DFT-----RKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEME 424 Query: 427 GIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFS 486 GI W+ I YFNN+II DLVE++HKGII+ILD+ C+ G TD FLE L K+GKHAHF Sbjct: 425 GIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFE 484 Query: 487 SRKLCASDKILEFD-RDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKN 545 +RKL +FR+ HYAG+V Y GF++KN D L++ K ++ S N +L+ Sbjct: 485 TRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 Query: 546 MWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDER 605 + L+ E +RP T T FKNS+ +L++ L SKEP Y+RCIKPND+K P FDD Sbjct: 545 CF---LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFL 601 Query: 606 CRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLIE 664 RHQ++YLGL+E++RVRRAGFA+R+ YE FL RYK + TWP+ H P+ E V++LI+ Sbjct: 602 IRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPA--EGVERLIK 659 Query: 665 RCGFQ-DDVAYGKTKIFIRTPRTLFTLEEL----RAQMLIRI------------------ 701 G++ ++ GKTKIFIR PRTLF E+ + Q++ RI Sbjct: 660 YIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQ 719 Query: 702 -VLFLQKVWRGTLARMRYKRTKAALTIIRYYRR------------------YKVKSYIHE 742 + L+ WRG LAR +R K A+ IIR + + + K+YI Sbjct: 720 AAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILN 779 Query: 743 VARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRA 802 + R+H KT+ D W PP +L + L+ + R + + I A ++ Sbjct: 780 L--RYHLPKTVLD----KSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQ 833 Query: 803 KVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCH 862 KV E+ +G++ G + ++ S+ D G P +L +K + + Sbjct: 834 KVVTSEIFRGRKD--GYTESLNQPFVNSRID----EGDINPKVLQLISHEK---IQYGVP 884 Query: 863 VRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHT 921 V K +R K R + +T + Y ++ K+ + I L G+S SN D ++V H Sbjct: 885 VIKYDRKGFKARQRQLILTQKAAYVVELA---KIKQKIEYSALKGVSTSNLSDGILVIHV 941 Query: 922 --KDNKD----LIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLH-- 973 +D+K ++ C + E V LV K E N+ N VQ SL Sbjct: 942 SPEDSKQKGDAVLQC---------GHVFEAVTKLVMLVKKE------NIVNVVQGSLQFF 986 Query: 974 ---GKKCTVSVETRLNQPQPDFTKNRSG 998 GK+ T+ +T L + KN++G Sbjct: 987 ISPGKEGTIVFDTGLEE---QVYKNKNG 1011 >gi|55956916 myosin IE [Homo sapiens] Length = 1108 Score = 564 bits (1453), Expect = e-160 Identities = 308/720 (42%), Positives = 448/720 (62%), Gaps = 35/720 (4%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL+ ++ + NL+ R+ I+T+IG V++SVNP+K + +G IE Y+G Sbjct: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PPH++A+AD Y+ M ++ C++ISGESGAGKT A+KYIM YI+ ++ + Sbjct: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK- 138 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F G+P GG I+N+LLEKS Sbjct: 139 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEFR 248 RV+++ PGERSFH FYQL++G S + SL + S+ Y Y+ + K I+D EF+ Sbjct: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQ 256 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKT 308 AM VIG EE V +I+A ILHLGN+ F G+ +E+ + ++ A LL Sbjct: 257 ETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQ 316 Query: 309 DMVEKALLYRTVAT----GRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 D +++ L R + + + I ++A Y RDA AKA++ R+F ++V IN +E Sbjct: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 + + IGVLDIYGFEIF N FEQFCIN+ NEKLQQ+FI+L LK EQEEY Sbjct: 377 KDHEEYN-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYV 429 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMN---VGKVTDEMFLEALNSKL 479 +EGI W I+YFNN+I+ DL+E + GI++ILDD C VG+ D+ L+ L ++ Sbjct: 430 QEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQI 489 Query: 480 GKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539 G H HF+S +++ F I HYAG V Y + GF ++N+D LF D LM +S Sbjct: 490 GSHEHFNS-----------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSE 538 Query: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599 P +K+++PE + + RP TA + K LV L P+Y+RCIKPN+ K P+ Sbjct: 539 LPFIKSLFPENLQA--DKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596 Query: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659 +++ R +HQVEYLGL EN+RVRRAG+A+R+ ++KFL RY ++++ TWP+ +K+ V Sbjct: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQ-GEEKQGV 655 Query: 660 KKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718 L++ D G++K+FI+ P +LF LEE+R + +QK WR +AR +Y Sbjct: 656 LHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKY 715 >gi|27544941 myosin IF [Homo sapiens] Length = 1098 Score = 539 bits (1388), Expect = e-153 Identities = 302/742 (40%), Positives = 446/742 (60%), Gaps = 33/742 (4%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D VL+ ++ ANLR RF I+T+IG V++SVNP+K + + I+ Y+G Sbjct: 18 GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 YE PPH++A+ D Y+ M ++ C++ISGESGAGKT A+KYIM YI+ ++ ++ Sbjct: 78 AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK- 136 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F G+P GG I+N+LLEKS Sbjct: 137 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249 RV++Q ER+FH +YQLL+G S++ ++L L Y +D ++F Sbjct: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTD 309 AM+VIG P Q V +++A ILHLGN+ F DG+ +E+ +++ A LL + Sbjct: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSG 315 Query: 310 MVEKALLYRTVAT---GR-DIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 +++ L R + + GR + I+ ++A+Y RDA AK +Y RLF ++V IN ++ Sbjct: 316 RLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQK 375 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 + + IGVLDIYGFEIF N FEQFCIN+ NEKLQQ+FI+L LK EQEEY + Sbjct: 376 PQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQ 428 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMNV---GKVTDEMFLEALNSKLG 480 EGI W I YFNN+++ DL+E + GI+++LDD C + G D+ L+ L + +G Sbjct: 429 EGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVG 488 Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 H HF+S + F I HYAG V Y V GF ++N+D LF D LM S Sbjct: 489 THEHFNS-----------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQ 537 Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 L+ ++PE KL + RP TA + K LV L P+Y+RCIKPN+ K P+ Sbjct: 538 AFLRMLFPE-KLD-GDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595 Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 +++ R +HQVEYLGL EN+RVRRAGFA+R+ + KFL RY +++ TWP +++ V+ Sbjct: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRW-RGDERQGVQ 654 Query: 661 KLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719 L+ + D G TK+F++ P +LF LEE+R + +QK WR +A +Y+ Sbjct: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 Query: 720 RTKAALTIIRYYRRYKVKSYIH 741 + + I ++ + ++ I+ Sbjct: 715 EMREEASNILLNKKERRRNSIN 736 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 478 bits (1229), Expect = e-134 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D + + ++ + NL +R+ IYT+ G ++V+VNPY+LL+IY + I QY + Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 ++ E PPH+FAIAD Y MKR S+D C +ISGESGAGKTE++K I+Q++AAI+ Q + Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 +E+ +L++ +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G G I YLLEKS Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248 RV Q ER++H FY +L+G SE + L L ++ S YNY+ +G + D+ E+ Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300 + AMKV+ F E + K+LAAILHLGNL++ + EN ++ Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355 Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 A LL + L RT+ T + + + ++A RDAF K IY RLF WIV +IN Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415 Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 I K + IG+LDI+GFE F NSFEQ CIN+ NE LQQ F++ V K EQ Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474 Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480 EEY E I W HI++ +NQ +D++ + II+++D+ K TD L LNS+ Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533 Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 +A++ K + F I H+AG V Y GF++KN+DTL D +L+++S N Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586 Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 +K ++ E KR T ++ FK S+ L+ L + +P++VRCIKPN+ K P + Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646 Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 FD C Q+ Y G++E +R+RRAG+ R ++ +F+ RY+++ P + + + Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706 Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719 ++ E G DD GKTKIF++ + LE R + + V+ LQKV RG R + Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765 Query: 720 RTKAALTIIRYYRR 733 + K A T+I+ + R Sbjct: 766 KLKNAATLIQRHWR 779 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 478 bits (1229), Expect = e-134 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D + + ++ + NL +R+ IYT+ G ++V+VNPY+LL+IY + I QY + Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 ++ E PPH+FAIAD Y MKR S+D C +ISGESGAGKTE++K I+Q++AAI+ Q + Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 +E+ +L++ +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G G I YLLEKS Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248 RV Q ER++H FY +L+G SE + L L ++ S YNY+ +G + D+ E+ Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300 + AMKV+ F E + K+LAAILHLGNL++ + EN ++ Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355 Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 A LL + L RT+ T + + + ++A RDAF K IY RLF WIV +IN Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415 Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 I K + IG+LDI+GFE F NSFEQ CIN+ NE LQQ F++ V K EQ Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474 Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480 EEY E I W HI++ +NQ +D++ + II+++D+ K TD L LNS+ Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533 Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 +A++ K + F I H+AG V Y GF++KN+DTL D +L+++S N Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586 Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 +K ++ E KR T ++ FK S+ L+ L + +P++VRCIKPN+ K P + Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646 Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 FD C Q+ Y G++E +R+RRAG+ R ++ +F+ RY+++ P + + + Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706 Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719 ++ E G DD GKTKIF++ + LE R + + V+ LQKV RG R + Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765 Query: 720 RTKAALTIIRYYRR 733 + K A T+I+ + R Sbjct: 766 KLKNAATLIQRHWR 779 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 478 bits (1229), Expect = e-134 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D + + ++ + NL +R+ IYT+ G ++V+VNPY+LL+IY + I QY + Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 ++ E PPH+FAIAD Y MKR S+D C +ISGESGAGKTE++K I+Q++AAI+ Q + Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 +E+ +L++ +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G G I YLLEKS Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248 RV Q ER++H FY +L+G SE + L L ++ S YNY+ +G + D+ E+ Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300 + AMKV+ F E + K+LAAILHLGNL++ + EN ++ Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355 Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 A LL + L RT+ T + + + ++A RDAF K IY RLF WIV +IN Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415 Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 I K + IG+LDI+GFE F NSFEQ CIN+ NE LQQ F++ V K EQ Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474 Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480 EEY E I W HI++ +NQ +D++ + II+++D+ K TD L LNS+ Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533 Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540 +A++ K + F I H+AG V Y GF++KN+DTL D +L+++S N Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586 Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600 +K ++ E KR T ++ FK S+ L+ L + +P++VRCIKPN+ K P + Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646 Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660 FD C Q+ Y G++E +R+RRAG+ R ++ +F+ RY+++ P + + + Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706 Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719 ++ E G DD GKTKIF++ + LE R + + V+ LQKV RG R + Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765 Query: 720 RTKAALTIIRYYRR 733 + K A T+I+ + R Sbjct: 766 KLKNAATLIQRHWR 779 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 471 bits (1213), Expect = e-132 Identities = 290/764 (37%), Positives = 438/764 (57%), Gaps = 59/764 (7%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G+ D + + P + NLR+RF + IYT+ G V+V++NPY+ L IYG D I Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 + + + PH+FA+A+ AYK M R ++ I++SGESGAGKT ++KY M+Y A ++ + Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 A VE +L SN ++E+ GNAKT RNDNSSRFGKY++I FD + IG ++ YLLEK Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYI-HVGAQLKSSINDAAEF 247 SRV+ Q ER++H FYQL + L L + ++NY G+ + ++DA E Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNA-DNFNYTKQGGSPVIEGVDDAKEM 305 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV-DGDTPLI-ENGKVVSIIAELLS 305 A ++G +++ILA ILHLGN+ F D D+ I + + I +L+ Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365 Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + + L +R +AT + K ++ +A+ RDA AK IY +LF WIV +N + Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH- 424 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 + +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F V K EQEEY + Sbjct: 425 -----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484 E IPW ID+++NQ ++L+E + GI+ +LD+ C + K TD+ + + L N+ L K A Sbjct: 480 EQIPWTLIDFYDNQPCINLIESK-LGILDLLDEEC-KMPKGTDDTWAQKLYNTHLNKCAL 537 Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 F +L ++ F I+H+A V Y GF++KNKDT+F++ +++ +S +L Sbjct: 538 FEKPRLS--------NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589 Query: 545 NMWPEGKLSI----------TEVTKRPL----------------TAATLFKNSMIALVDN 578 ++ + + +I T +T+ P T F+NS+ L++ Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649 Query: 579 LASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHR 638 L + P+YVRCIKPND K P FD++R Q+ G+LE +R+ AGF R TY++F R Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709 Query: 639 YKMISEFTWPNHDLPSD-KEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQ 696 Y+++ + D+ SD K+ K ++E+ +D +GKTKIF R + + LE+LRA Sbjct: 710 YRVLMK----QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764 Query: 697 MLIRIVLFLQKVWRGTLARMRYKR-TKAALTIIRYYRRYKVKSY 739 L + +QK RG L R +Y R KAA+T+ RY R Y+ + Y Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 471 bits (1213), Expect = e-132 Identities = 290/764 (37%), Positives = 438/764 (57%), Gaps = 59/764 (7%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G+ D + + P + NLR+RF + IYT+ G V+V++NPY+ L IYG D I Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 + + + PH+FA+A+ AYK M R ++ I++SGESGAGKT ++KY M+Y A ++ + Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 A VE +L SN ++E+ GNAKT RNDNSSRFGKY++I FD + IG ++ YLLEK Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYI-HVGAQLKSSINDAAEF 247 SRV+ Q ER++H FYQL + L L + ++NY G+ + ++DA E Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNA-DNFNYTKQGGSPVIEGVDDAKEM 305 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV-DGDTPLI-ENGKVVSIIAELLS 305 A ++G +++ILA ILHLGN+ F D D+ I + + I +L+ Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365 Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + + L +R +AT + K ++ +A+ RDA AK IY +LF WIV +N + Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH- 424 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 + +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F V K EQEEY + Sbjct: 425 -----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484 E IPW ID+++NQ ++L+E + GI+ +LD+ C + K TD+ + + L N+ L K A Sbjct: 480 EQIPWTLIDFYDNQPCINLIESK-LGILDLLDEEC-KMPKGTDDTWAQKLYNTHLNKCAL 537 Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 F +L ++ F I+H+A V Y GF++KNKDT+F++ +++ +S +L Sbjct: 538 FEKPRLS--------NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589 Query: 545 NMWPEGKLSI----------TEVTKRPL----------------TAATLFKNSMIALVDN 578 ++ + + +I T +T+ P T F+NS+ L++ Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649 Query: 579 LASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHR 638 L + P+YVRCIKPND K P FD++R Q+ G+LE +R+ AGF R TY++F R Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709 Query: 639 YKMISEFTWPNHDLPSD-KEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQ 696 Y+++ + D+ SD K+ K ++E+ +D +GKTKIF R + + LE+LRA Sbjct: 710 YRVLMK----QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764 Query: 697 MLIRIVLFLQKVWRGTLARMRYKR-TKAALTIIRYYRRYKVKSY 739 L + +QK RG L R +Y R KAA+T+ RY R Y+ + Y Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 469 bits (1206), Expect = e-132 Identities = 285/751 (37%), Positives = 426/751 (56%), Gaps = 54/751 (7%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G+ D + + P + NLR+RF + + IYT+ G ++V++NPYK L IYG I Y G Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 + + + PH+FA+A+ AYK M R +++ I++SGESGAGKT +++Y M+Y A ++ Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 A VE + +L SN + EA GNAKT RNDNSSRFGKY +I+FD + IG +++ YLLEK Sbjct: 188 AHVE---DKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQ-LKSSINDAAEF 247 SRV+ Q ER++H FYQL + + L L S +NY +G + +ND AE Sbjct: 245 SRVVFQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRMGGNTVIEGVNDRAEM 303 Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGD--TPLIENGKVVSIIAELLS 305 ++GFK + V+KILAAILHLGN++ G+ + + E+ + + ELL Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLG 363 Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 ++ V + L R + T + + K T +A RDA AK IY LF +IV RIN ++ Sbjct: 364 LESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQF 423 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 ++T IGVLDIYGFE FD NSFEQFCINY NEKLQQ F V K EQEEY + Sbjct: 424 SGK------QHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484 E IPW ID+++NQ ++DL+E + GI+ +LD+ C+ + TDE +L+ L N+ + ++ Sbjct: 478 EDIPWTLIDFYDNQPVIDLIEAK-MGILELLDEECL-LPHGTDENWLQKLYNNFVNRNPL 535 Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 F ++ + F I+H+A V Y GF++KN+DT++ ++ S + Sbjct: 536 FEKPRMS--------NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCA 587 Query: 545 NMW--------PEGKLSITEVTKRPL---------TAATLFKNSMIALVDNLASKEPYYV 587 N + P G + + K+ + T + F++S+ L++ L + P+YV Sbjct: 588 NFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYV 647 Query: 588 RCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI---SE 644 RCIKPND+K P FD +R Q+ G+LE +R+ + R TY +F RY ++ E Sbjct: 648 RCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQE 707 Query: 645 FTWPNHDLPSDKEAVKKLIERCGFQDDVAY--GKTKIFIRTPRTLFTLEELRAQMLIRIV 702 ++ SDK+ V K++ QD Y GKTKIF R + + LE+LR L + Sbjct: 708 LSF------SDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAY-LEKLRLDKLRQSC 760 Query: 703 LFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733 + +QK RG L R ++ R + A II+ Y R Sbjct: 761 VMVQKHMRGWLQRKKFLRERRAALIIQQYFR 791 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 459 bits (1182), Expect = e-129 Identities = 274/757 (36%), Positives = 438/757 (57%), Gaps = 45/757 (5%) Query: 8 EFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYK 67 E G D ++ + ++NL++RFE+ IYT+IG ++VSVNPY++ IYG + ++QY Sbjct: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYN 1280 Query: 68 GRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQ 127 GR L E PPHLFA+A+ A+ M ++ CI+ISGESG+GKTEA+K I++Y+AA+ + Sbjct: 1281 GRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN--QK 1338 Query: 128 RAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI-NNYLL 186 R ++++K +L++ +LE+FGNAKT RNDNSSRFGK+++I + G I G I + YLL Sbjct: 1339 REVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLL 1394 Query: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAA 245 EKSR++ Q ER++H FY+LL G Q+ ++ LQ++ +Y Y++ G + + +DA Sbjct: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEA-ETYYYLNQGGNCEIAGKSDAD 1453 Query: 246 EFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNL---KFVVDG-DTPLIENGKVVSIIA 301 +FR + AM+V+GF E+ ++++ILA+ILHLGN+ K+ D + + + + + +A Sbjct: 1454 DFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVA 1513 Query: 302 ELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIND 361 ELL + ++KA+ ++ T R+ I T + A RDA AK +Y LF W++TR+N Sbjct: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573 Query: 362 IIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQE 421 ++ + DT I +LDIYGFE NSFEQ CINY NE LQ LF ++V ++EQE Sbjct: 1574 LVSPRQ-DT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQE 1626 Query: 422 EYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGK 481 EY RE I W+ I + +NQ ++L+ + GI+ ILDD C + TD FL+ + G Sbjct: 1627 EYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCC-FPQATDHTFLQKCHYHHGA 1685 Query: 482 HAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNP 541 + +S K+ +F I+HYAG V Y V F+DKN D + QD L S Sbjct: 1686 NPLYSKPKMPLP--------EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTR 1737 Query: 542 VLKNMWPE----------GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIK 591 V+ +++ GK S + T A F+ S++ LV+ + P ++RC+K Sbjct: 1738 VVAHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLK 1797 Query: 592 PNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHD 651 PN KK P +F+ + Q+ Y G+LE VR+R+ GF R ++ F+ RY + HD Sbjct: 1798 PNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVAL---KHD 1854 Query: 652 LPSDKEAVKKLIER-CGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVW 709 LP++ + ++ R C ++ G +K+F++ LE +R +L L LQ+ Sbjct: 1855 LPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK-EHLYQLLESMREHVLNLAALTLQRCL 1913 Query: 710 RGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARR 746 RG + R++ + + +++ R + ++ RR Sbjct: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRR 1950 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 451 bits (1161), Expect = e-126 Identities = 281/757 (37%), Positives = 426/757 (56%), Gaps = 54/757 (7%) Query: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69 G D + + ++ + NL +R+++ +IYT+ G ++V+VNP+++L +Y + ++ Y R Sbjct: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125 Query: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129 + E PPH+FAIA+ Y +MKR +D C +ISGESGAGKTE +K I+Q++A I+ Q + Sbjct: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS--GQHS 183 Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189 +E+ +L++N +LEAFGNAKT RNDNSSRFGKY+DI F+ G G I +LLEKS Sbjct: 184 WIEQ---QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240 Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVG-AQLKSSINDAAEFR 248 RV Q P ER++H FY +L G S + + L L + S Y+Y+ +G +NDA ++ Sbjct: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYA 299 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV----DGDTPLIENGKVVSIIAELL 304 + AMK++ F E V K+LAAILHLGN+ F+ + D + + +LL Sbjct: 300 HIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLL 359 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 + + L+ T+ + + + +A+ RDAF K IY LF WIV +IN I Sbjct: 360 EVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIF 419 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 + + IG+LDI+GFE F+NNSFEQ CIN+ NE LQQ F+Q V EQEEY+ Sbjct: 420 TPPAQDPKNVRR-AIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478 Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484 E I W +I Y +N+ +DL+ + II++LD+ + TD L+ LNS H Sbjct: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEE-SRFPQGTDLTMLQKLNS-----VH 532 Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 +++ I D F I H+AG+V Y GF++KN+D L D L+Y+S N L+ Sbjct: 533 ANNKAFLQPKNI--HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590 Query: 545 NMW----PEGKL---------------SITEVTKRPLTAATLFKNSMIALVDNLASKEPY 585 ++ E KL + KRP T + FK S+ L+ L + +PY Sbjct: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650 Query: 586 YVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEF 645 ++RCIKPN+ K P +FD E C Q+ Y G++E V +R++GF R T+E+F R+ ++ Sbjct: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVL--- 707 Query: 646 TWPNHDLPSDKEAVKKLIERCGFQD-------DVAYGKTKIFIRTPRTLFTLEELRAQML 698 PN + ++++ G D D GKTKIF+R + LE R+Q+L Sbjct: 708 -LPNAMRMQLQGKLRQM--TLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVL 763 Query: 699 IRIVLFLQKVWRGTLARMRY-KRTKAALTIIRYYRRY 734 R L +QKV RG R + ++ +AA+T+ ++R Y Sbjct: 764 DRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGY 800 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 450 bits (1157), Expect = e-126 Identities = 281/799 (35%), Positives = 430/799 (53%), Gaps = 55/799 (6%) Query: 10 GKADFVLMDTVSMPEFMANLRLRF-EKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 G+ D + + P + NL++RF E IYT+ G V+V++NPY+ L IYG+D I Y G Sbjct: 70 GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129 Query: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 + + + PH+FA+A+ AYK M R K+ I++SGESGAGKT ++KY M+Y A + + Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE 189 Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 +E +L S+ ++EA GNAKT RNDNSSRFGKY+ I FD + IG ++ YLLEK Sbjct: 190 TNIEE---KVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248 SRV+ Q ER++H FYQL + L L + + G ++DA +F Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFE 306 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV--DGDTPLIENGKV-VSIIAELLS 305 A ++G K +++KI+A+ILHLG++ DGD+ I V +S LL Sbjct: 307 KTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLG 366 Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 + +E L +R + T + K + Q+ R+A AK IY +LF WIV IN + Sbjct: 367 VEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH- 425 Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 T +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F V K EQEEY + Sbjct: 426 -----TSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480 Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485 E IPW ID+++NQ +DL+E + GI+ +LD+ C V K TD+ + + L + HF Sbjct: 481 EQIPWTLIDFYDNQPCIDLIEAK-LGILDLLDEEC-KVPKGTDQNWAQKLYDRHSSSQHF 538 Query: 486 SSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKN 545 ++ + F I H+A V Y GF++KN+DT++++ ++ S P++ + Sbjct: 539 QKPRMS--------NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVAD 590 Query: 546 MWPE----------GKLSITEVTKRPL-------------TAATLFKNSMIALVDNLASK 582 ++ + GK S ++++ R T F+ S+ L++ L + Sbjct: 591 LFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNAT 650 Query: 583 EPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI 642 P+YVRCIKPND+K P FD +R Q+ G+LE +R+ AG+ R Y F +RY+++ Sbjct: 651 TPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL 710 Query: 643 SEFTWPNHDLPSDKEAV-KKLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIR 700 + +DK+A+ + ++E D +G+TKIF R + + LE+LRA Sbjct: 711 VK---KRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAY-LEKLRADKFRT 766 Query: 701 IVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHV 760 + +QK RG L +++Y R K A ++ Y R + + E RR ++ KH Sbjct: 767 ATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQ---KHY 823 Query: 761 KWPSPPKVLRRFEEALQTI 779 + + +R A I Sbjct: 824 RMQRARQAYQRVRRAAVVI 842 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 439 bits (1130), Expect = e-123 Identities = 302/881 (34%), Positives = 461/881 (52%), Gaps = 62/881 (7%) Query: 3 EQESLEFGKA-DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRD 61 +Q +F K D ++ + P + NL+ R+ IYT+ G V+VNPYK L +Y + Sbjct: 78 QQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPE 137 Query: 62 TIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAA 121 + Y+G++ E PPH+F+I+D AY+ M ++ I+I+GESGAGKT +K ++QY A Sbjct: 138 VVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAV 197 Query: 122 ITNPSQRAEVER------VKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGD 175 I R++ ++ +++ ++++N LEAFGNAKT RNDNSSRFGK++ I+F G Sbjct: 198 IAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 257 Query: 176 PIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGA 235 I YLLEKSRVI Q ER +H FYQ+L ++L L + + Y +I G Sbjct: 258 LASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGE 317 Query: 236 QLKSSINDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--N 293 +SI+DA E +A V+GF EE ++YK+ AI+H GN+KF + E Sbjct: 318 TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDG 377 Query: 294 GKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFC 353 + A L+ + + K L + V G + + K Q+ Y A AKA+YER+F Sbjct: 378 TEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFN 437 Query: 354 WIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQ 413 W+VTRIN +E K + IGVLDI GFEIFD NSFEQ CIN+ NEKLQQ F Sbjct: 438 WMVTRINATLETK------QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNH 491 Query: 414 LVLKQEQEEYQREGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFL 472 + EQEEY++EGI W ID+ + Q +DL+E+ GI++IL++ CM K TD F Sbjct: 492 HMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKP-MGIMSILEEECM-FPKATDMTFK 549 Query: 473 EAL-NSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDF 531 L ++ LGK A+F + + F + HYAG V Y++IG++ KNKD L + Sbjct: 550 AKLFDNHLGKSANFQKPRNIKGKP----EAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605 Query: 532 KRLMYNSSNPVLKNMWPEGKLSITEVTKRP---------LTAATLFKNSMIALVDNLASK 582 L SS +L ++ + + K T + L + ++ L+ NL S Sbjct: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665 Query: 583 EPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI 642 P++VRCI PN+ KSP + D+ HQ+ G+LE +R+ R GF R Y F RY+++ Sbjct: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725 Query: 643 SEFTWPNHDLPSDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRI 701 + P ++ +KL+ + +G TK+F + L LEE+R + L RI Sbjct: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSRI 784 Query: 702 VLFLQKVWRGTLARMRYKR---TKAALTIIRYYRRYKVKSYIHEVARRFHGVKT---MRD 755 + +Q RG LARM YK+ + +L +I++ R F GVK M+ Sbjct: 785 ITRIQAQSRGVLARMEYKKLLERRDSLLVIQWN------------IRAFMGVKNWPWMKL 832 Query: 756 YGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRA 815 Y K +K +L+ E + + ++L +++ S+ + + V +L+ ++ Sbjct: 833 YFK-IK-----PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ-EKN 885 Query: 816 DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMN 856 DL LQ E + LA D + + +L+ K K MN Sbjct: 886 DLQLQVQAEQDNLA---DAEERCDQLIKNKIQLEAKVKEMN 923 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 439 bits (1128), Expect = e-123 Identities = 270/748 (36%), Positives = 412/748 (55%), Gaps = 42/748 (5%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D + ++ + NL+ R+ G IYT+ G V +NPYK L IY + IE Y+G++ + Sbjct: 89 DMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRH 148 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132 E PPH++AI+++AY+ M + +D I+ +GESGAGKTE +K ++QY+A + + + + Sbjct: 149 EMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDH 208 Query: 133 RV----KNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 + + LL++N +LE+FGNAKT +NDNSSRFGK++ INFD G +G +I YLLEK Sbjct: 209 NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248 SR + Q ER+FH FYQLL G E L+S L + ++Y ++ G D F+ Sbjct: 269 SRAVRQAKDERTFHIFYQLLSGAGEH-LKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQ 327 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306 +AM ++GF EEI ++ K+++++L GN+ F + +T + V + LL Sbjct: 328 ETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGM 387 Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366 +A+L + GRD + K T+++A + +A AKA YERLF W+V RIN K Sbjct: 388 NVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRIN-----K 442 Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426 D T + IG+LDI GFEIF+ NSFEQ CINY NEKLQQLF + EQEEYQRE Sbjct: 443 ALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502 Query: 427 GIPWKHIDY-FNNQIIVDLVEQ--QHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483 GI W ID+ + Q +DL+E+ G++A+LD+ C K TD+ F+E L + G H+ Sbjct: 503 GIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW-FPKATDKTFVEKLVQEQGSHS 561 Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543 F + L+ DF I HYAG V Y ++ KN D L + L++ SS+ + Sbjct: 562 KFQ------KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFV 615 Query: 544 KNMWPE-----GKLSITEVTKRPL------------TAATLFKNSMIALVDNLASKEPYY 586 +W + G +T +T+ T L+K S+ L+ L + P + Sbjct: 616 AELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNF 675 Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646 VRCI PN +K D Q+ G+LE +R+ R GF R +++F RY++++ Sbjct: 676 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735 Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705 P K+A +++I ++ G++KIF R L LEE R + I++F Sbjct: 736 IPK-GFMDGKQACERMIRALELDPNLYRIGQSKIFFRA-GVLAHLEEERDLKITDIIIFF 793 Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733 Q V RG LAR + + + L+ ++ +R Sbjct: 794 QAVCRGYLARKAFAKKQQQLSALKVLQR 821 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 439 bits (1128), Expect = e-123 Identities = 267/735 (36%), Positives = 402/735 (54%), Gaps = 39/735 (5%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D +M ++ + NLR R+ + IYT+ G V++NPYK L +Y + YKG+ Sbjct: 130 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAIT----NPSQR 128 + PPH++A+AD AY M R + ++I+GESGAGKT +K ++QY A + P ++ Sbjct: 190 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249 Query: 129 AEVERVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHIN 182 A+ K + ++++N +EAFGNAKT RNDNSSRFGK++ I+F G I+ Sbjct: 250 AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309 Query: 183 NYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN 242 +YLLEKSRVI Q PGERS+H +YQ+L G ++ L L + Y++ G ++N Sbjct: 310 SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITVDNMN 369 Query: 243 DAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSI--I 300 D E AM ++GF +E YKI+ A+LH GN+KF E S Sbjct: 370 DGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKA 429 Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360 A L+ + + K LL+ V G + + K + ++ + A AKA Y+RLF W+V+RIN Sbjct: 430 AYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRIN 489 Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420 ++ K + IGVLDI GFEIF+ NSFEQ CIN+ NEKLQQ F Q + EQ Sbjct: 490 QTLDTK------LPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQ 543 Query: 421 EEYQREGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSK 478 EEY+REGI W ID+ + Q +DL+E+ GI++IL++ CM K +D F L ++ Sbjct: 544 EEYKREGIDWVFIDFGLDLQPCIDLIEKP-LGILSILEEECM-FPKASDASFRAKLYDNH 601 Query: 479 LGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNS 538 GK +F + DK ++ F + HYAG V YS++G+++KNKD L + + S Sbjct: 602 AGKSPNFQQPR---PDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKS 658 Query: 539 SNPVLKNMWPE---------GKLSITEVTKRPL---TAATLFKNSMIALVDNLASKEPYY 586 N +L ++ K + E K+ T + L K ++ L+ NL + +P++ Sbjct: 659 QNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718 Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646 VRCI PN+ K+P + D HQ+ G+LE +R+ R GF R Y F RY++++ Sbjct: 719 VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778 Query: 647 WPNHDLPSDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705 P+ ++A +KL+ +G TK+F + L LEELR Q L +++ L Sbjct: 779 IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKA-GLLGVLEELRDQRLAKVLTLL 837 Query: 706 QKVWRGTLARMRYKR 720 Q RG L R+ Y+R Sbjct: 838 QARSRGRLMRLEYQR 852 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 435 bits (1119), Expect = e-122 Identities = 267/748 (35%), Positives = 413/748 (55%), Gaps = 42/748 (5%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D + ++ + NLR R+ G IYT+ G V VNPYK L IY ++ YKG++ + Sbjct: 89 DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130 E PPH++AIAD AY++M + +D I+ +GESGAGKTE +K ++QY+A + + + + Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208 Query: 131 --VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 ++ LL++N +LEAFGNAKT +NDNSSRFGK++ INFD G +G +I YLLEK Sbjct: 209 SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248 SR I Q ER+FH FY ++ G E+M RS L + ++Y ++ G + D F+ Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQ 327 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306 +AM ++GF EE ++ K+++++L LGN+ F + +T + + + L+ Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387 Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366 +++L + GRD++ K T+++A + +A AKA YERLF WI+TR+N K Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN-----K 442 Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426 D T + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF + EQEEYQRE Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502 Query: 427 GIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483 GI W ID+ + Q ++L+E+ + G++A+LD+ C K TD+ F+E L ++ G H Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLCTEQGSHP 561 Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543 F K L+ +F I HYAG V Y+ ++ KN D L + L+ SS+ + Sbjct: 562 KFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615 Query: 544 KNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNLASKEPYY 586 ++W E L TK+ + T L+K + L+ L + P + Sbjct: 616 ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675 Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646 VRCI PN +K D Q+ G+LE +R+ R GF R +++F RY++++ Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735 Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705 P K+A +I+ ++ G++KIF RT L LEE R + +++ Sbjct: 736 IPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMAF 793 Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733 Q + RG LAR + + + LT ++ +R Sbjct: 794 QAMCRGYLARKAFAKRQQQLTAMKVIQR 821 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 435 bits (1119), Expect = e-122 Identities = 267/748 (35%), Positives = 413/748 (55%), Gaps = 42/748 (5%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D + ++ + NLR R+ G IYT+ G V VNPYK L IY ++ YKG++ + Sbjct: 89 DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130 E PPH++AIAD AY++M + +D I+ +GESGAGKTE +K ++QY+A + + + + Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208 Query: 131 --VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 ++ LL++N +LEAFGNAKT +NDNSSRFGK++ INFD G +G +I YLLEK Sbjct: 209 SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268 Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248 SR I Q ER+FH FY ++ G E+M RS L + ++Y ++ G + D F+ Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQ 327 Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306 +AM ++GF EE ++ K+++++L LGN+ F + +T + + + L+ Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387 Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366 +++L + GRD++ K T+++A + +A AKA YERLF WI+TR+N K Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN-----K 442 Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426 D T + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF + EQEEYQRE Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502 Query: 427 GIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483 GI W ID+ + Q ++L+E+ + G++A+LD+ C K TD+ F+E L ++ G H Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLCTEQGSHP 561 Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543 F K L+ +F I HYAG V Y+ ++ KN D L + L+ SS+ + Sbjct: 562 KFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615 Query: 544 KNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNLASKEPYY 586 ++W E L TK+ + T L+K + L+ L + P + Sbjct: 616 ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675 Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646 VRCI PN +K D Q+ G+LE +R+ R GF R +++F RY++++ Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735 Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705 P K+A +I+ ++ G++KIF RT L LEE R + +++ Sbjct: 736 IPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMAF 793 Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733 Q + RG LAR + + + LT ++ +R Sbjct: 794 QAMCRGYLARKAFAKRQQQLTAMKVIQR 821 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 432 bits (1111), Expect = e-121 Identities = 265/749 (35%), Positives = 408/749 (54%), Gaps = 34/749 (4%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D ++ ++ P + NL+ R+ IYT+ G V+VNPYK L +Y + +E Y+G++ Sbjct: 90 DMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQ 149 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132 E PPH+F+I+D AY+ M ++ I+I+GESGAGKT +K ++QY A I A+ + Sbjct: 150 EAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK 209 Query: 133 RVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLL 186 K + ++ +N +LEAFGNAKT RNDNSSRFGK++ I+F G I YLL Sbjct: 210 DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLL 269 Query: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAE 246 EKSRV Q ERS+H FYQ+L +++ L + + Y +I G L +SI+DA E Sbjct: 270 EKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDAEE 329 Query: 247 FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--NGKVVSIIAELL 304 A+ ++GF PEE +YK+ A++H GN+KF E +V A L+ Sbjct: 330 LLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLM 389 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 + + KAL + V G + + K T + + +A +K++YE+LF W+VTRIN ++ Sbjct: 390 GLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD 449 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 K + IGVLDI GFEIF+ NS EQ CIN+ NEKLQQ F + EQEEY+ Sbjct: 450 TK------LPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503 Query: 425 REGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKH 482 +EGI W ID+ + ++L+E+ GI +IL++ CM K TD F L + LGK Sbjct: 504 KEGIEWTFIDFGMDLAACIELIEKP-MGIFSILEEECM-FPKATDTSFKNKLYDQHLGKS 561 Query: 483 AHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPV 542 +F K+ + F + HYAG V YSV G+++KNKD L + L SSN + Sbjct: 562 NNFQKPKVVKG----RAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRL 617 Query: 543 LKNMWPEGKLSITEVTKRPL---------TAATLFKNSMIALVDNLASKEPYYVRCIKPN 593 L +++ + + K+ + T + LF+ ++ L+ NL + P++VRCI PN Sbjct: 618 LAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677 Query: 594 DKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLP 653 + K+P + HQ+ G+LE +R+ R GF R Y F RY++++ P Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFI 737 Query: 654 SDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGT 712 K+A +KL+ +G TK+F + L TLEE+R L +++ Q V RG Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKA-GLLGTLEEMRDDRLAKLITRTQAVCRGF 796 Query: 713 LARMRYKRTKAALTIIRYYRRYKVKSYIH 741 L R+ +++ I + +Y ++S+++ Sbjct: 797 LMRVEFQKMVQRRESI-FCIQYNIRSFMN 824 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 432 bits (1111), Expect = e-121 Identities = 267/755 (35%), Positives = 413/755 (54%), Gaps = 49/755 (6%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D + ++ + NLR R+ G IYT+ G V VNPYK L IY ++ YKG++ + Sbjct: 89 DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130 E PPH++AIAD AY++M + +D I+ +GESGAGKTE +K ++QY+A + + + + Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208 Query: 131 ---------VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI 181 ++ LL++N +LEAFGNAKT +NDNSSRFGK++ INFD G +G +I Sbjct: 209 SITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 268 Query: 182 NNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSI 241 YLLEKSR I Q ER+FH FY ++ G E+M RS L + ++Y ++ G + Sbjct: 269 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAA 327 Query: 242 NDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSI 299 D F+ +AM ++GF EE ++ K+++++L LGN+ F + +T + + Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387 Query: 300 IAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRI 359 + L+ +++L + GRD++ K T+++A + +A AKA YERLF WI+TR+ Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447 Query: 360 NDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQE 419 N K D T + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF + E Sbjct: 448 N-----KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502 Query: 420 QEEYQREGIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALN 476 QEEYQREGI W ID+ + Q ++L+E+ + G++A+LD+ C K TD+ F+E L Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLC 561 Query: 477 SKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMY 536 ++ G H F K L+ +F I HYAG V Y+ ++ KN D L + L+ Sbjct: 562 TEQGSHPKFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 615 Query: 537 NSSNPVLKNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNL 579 SS+ + ++W E L TK+ + T L+K + L+ L Sbjct: 616 ASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTL 675 Query: 580 ASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY 639 + P +VRCI PN +K D Q+ G+LE +R+ R GF R +++F RY Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735 Query: 640 KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQML 698 ++++ P K+A +I+ ++ G++KIF RT L LEE R + Sbjct: 736 EILAANAIPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKI 793 Query: 699 IRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733 +++ Q + RG LAR + + + LT ++ +R Sbjct: 794 TDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQR 828 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 432 bits (1111), Expect = e-121 Identities = 267/755 (35%), Positives = 413/755 (54%), Gaps = 49/755 (6%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D + ++ + NLR R+ G IYT+ G V VNPYK L IY ++ YKG++ + Sbjct: 89 DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130 E PPH++AIAD AY++M + +D I+ +GESGAGKTE +K ++QY+A + + + + Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208 Query: 131 ---------VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI 181 ++ LL++N +LEAFGNAKT +NDNSSRFGK++ INFD G +G +I Sbjct: 209 SITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 268 Query: 182 NNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSI 241 YLLEKSR I Q ER+FH FY ++ G E+M RS L + ++Y ++ G + Sbjct: 269 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAA 327 Query: 242 NDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSI 299 D F+ +AM ++GF EE ++ K+++++L LGN+ F + +T + + Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387 Query: 300 IAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRI 359 + L+ +++L + GRD++ K T+++A + +A AKA YERLF WI+TR+ Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447 Query: 360 NDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQE 419 N K D T + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF + E Sbjct: 448 N-----KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502 Query: 420 QEEYQREGIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALN 476 QEEYQREGI W ID+ + Q ++L+E+ + G++A+LD+ C K TD+ F+E L Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLC 561 Query: 477 SKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMY 536 ++ G H F K L+ +F I HYAG V Y+ ++ KN D L + L+ Sbjct: 562 TEQGSHPKFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 615 Query: 537 NSSNPVLKNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNL 579 SS+ + ++W E L TK+ + T L+K + L+ L Sbjct: 616 ASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTL 675 Query: 580 ASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY 639 + P +VRCI PN +K D Q+ G+LE +R+ R GF R +++F RY Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735 Query: 640 KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQML 698 ++++ P K+A +I+ ++ G++KIF RT L LEE R + Sbjct: 736 EILAANAIPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKI 793 Query: 699 IRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733 +++ Q + RG LAR + + + LT ++ +R Sbjct: 794 TDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQR 828 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 430 bits (1105), Expect = e-120 Identities = 271/741 (36%), Positives = 398/741 (53%), Gaps = 36/741 (4%) Query: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72 D +M + P + NL+ R+ IYT+ G V+VNPYK L +Y + + Y+G++ Sbjct: 92 DMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQ 151 Query: 73 ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132 E PPH+F+I+D AY+ M ++ I+I+GESGAGKT +K ++QY A I ++ + E Sbjct: 152 EAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDE 211 Query: 133 RVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLL 186 K + ++ +N +LEAFGNAKT RNDNSSRFGK++ I+F G I YLL Sbjct: 212 SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLL 271 Query: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAE 246 EKSRV Q ERS+H FYQ+ ++ L + + Y ++ G SI+D E Sbjct: 272 EKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEE 331 Query: 247 FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--NGKVVSIIAELL 304 A+ ++GF PEE ++YK+ A++H GN+KF E +V A L Sbjct: 332 LMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391 Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364 S + + KAL Y V G + + K T Q+ A AKA+YE++F W+VTRIN ++ Sbjct: 392 SLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD 451 Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424 K + IGVLDI GFEIFD NS EQ CIN+ NEKLQQ F + EQEEY+ Sbjct: 452 TK------QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505 Query: 425 REGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKH 482 +EGI W ID+ + ++L+E+ GI +IL++ CM K TD F L + LGK Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKP-LGIFSILEEECM-FPKATDTSFKNKLYDQHLGKS 563 Query: 483 AHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPV 542 A+F K+ + + F + HYAG V Y++ G++DKNKD L L S+ Sbjct: 564 ANFQKPKVVKG----KAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKT 619 Query: 543 LKNMW-----PEGKLSITEVTKRP----LTAATLFKNSMIALVDNLASKEPYYVRCIKPN 593 L +++ E S + K+ T + LF+ ++ L+ NL S P++VRCI PN Sbjct: 620 LASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 679 Query: 594 DKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLP 653 + K+P + E HQ+ G+LE +R+ R GF R Y F RYK+++ P Sbjct: 680 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFI 739 Query: 654 SDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGT 712 K+A +KL+ +G TK+F + L LEE+R + L +I+ Q V RG Sbjct: 740 DSKKASEKLLASIDIDHTQYKFGHTKVFFKA-GLLGLLEEMRDEKLAQIITRTQAVCRGF 798 Query: 713 LARMRYKR---TKAALTIIRY 730 L R+ Y++ + AL I+Y Sbjct: 799 LMRVEYQKMLQRREALFCIQY 819 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,895,468 Number of Sequences: 37866 Number of extensions: 1459012 Number of successful extensions: 3569 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 3098 Number of HSP's gapped (non-prelim): 124 length of query: 1006 length of database: 18,247,518 effective HSP length: 112 effective length of query: 894 effective length of database: 14,006,526 effective search space: 12521834244 effective search space used: 12521834244 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.