Guide to the Human Genome
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Search of human proteins with 51100974

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51100974 myosin ID [Homo sapiens]
         (1006 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51100974 myosin ID [Homo sapiens]                                 2017   0.0  
gi|239582755 myosin IG [Homo sapiens]                                1241   0.0  
gi|44889481 myosin IB isoform 2 [Homo sapiens]                        717   0.0  
gi|194328685 myosin IB isoform 1 [Homo sapiens]                       705   0.0  
gi|240120050 myosin IB isoform 1 [Homo sapiens]                       705   0.0  
gi|124494247 myosin IC isoform b [Homo sapiens]                       697   0.0  
gi|124494238 myosin IC isoform a [Homo sapiens]                       697   0.0  
gi|124494240 myosin IC isoform c [Homo sapiens]                       697   0.0  
gi|4885503 myosin IA [Homo sapiens]                                   690   0.0  
gi|254028267 myosin 1H [Homo sapiens]                                 667   0.0  
gi|55956916 myosin IE [Homo sapiens]                                  564   e-160
gi|27544941 myosin IF [Homo sapiens]                                  539   e-153
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     478   e-134
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     478   e-134
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     478   e-134
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       471   e-132
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       471   e-132
gi|153945715 myosin VC [Homo sapiens]                                 469   e-132
gi|118402590 myosin XV [Homo sapiens]                                 459   e-129
gi|122937512 myosin VIIB [Homo sapiens]                               451   e-126
gi|122937345 myosin VB [Homo sapiens]                                 450   e-126
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...   439   e-123
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   439   e-123
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...   439   e-123
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   435   e-122
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   435   e-122
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...   432   e-121
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   432   e-121
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   432   e-121
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...   430   e-120

>gi|51100974 myosin ID [Homo sapiens]
          Length = 1006

 Score = 2017 bits (5226), Expect = 0.0
 Identities = 1006/1006 (100%), Positives = 1006/1006 (100%)

Query: 1    MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60
            MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR
Sbjct: 1    MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60

Query: 61   DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120
            DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA
Sbjct: 61   DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120

Query: 121  AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180
            AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH
Sbjct: 121  AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180

Query: 181  INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240
            INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS
Sbjct: 181  INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240

Query: 241  INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII 300
            INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII
Sbjct: 241  INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII 300

Query: 301  AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360
            AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN
Sbjct: 301  AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360

Query: 361  DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420
            DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ
Sbjct: 361  DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420

Query: 421  EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480
            EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG
Sbjct: 421  EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480

Query: 481  KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540
            KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN
Sbjct: 481  KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540

Query: 541  PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600
            PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI
Sbjct: 541  PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600

Query: 601  FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660
            FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK
Sbjct: 601  FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660

Query: 661  KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR 720
            KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR
Sbjct: 661  KLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKR 720

Query: 721  TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF 780
            TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF
Sbjct: 721  TKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIF 780

Query: 781  NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT 840
            NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT
Sbjct: 781  NRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGT 840

Query: 841  FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP 900
            FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP
Sbjct: 841  FVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIP 900

Query: 901  LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL 960
            LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL
Sbjct: 901  LYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHL 960

Query: 961  QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN 1006
            QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN
Sbjct: 961  QVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN 1006


>gi|239582755 myosin IG [Homo sapiens]
          Length = 1018

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 611/1016 (60%), Positives = 783/1016 (77%), Gaps = 12/1016 (1%)

Query: 1    MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60
            M ++E  E+GK DFVL+D V+M +FM NL+LRFEKGRIYT+IGEV+VSVNPY+ L +YG 
Sbjct: 1    MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP 60

Query: 61   DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120
            + I +Y+GRELYERPPHL+A+A+AAYKAMK RS+DTCIVISGESGAGKTEASK+IMQYIA
Sbjct: 61   EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA 120

Query: 121  AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180
            A+TNPSQRAEVERVK++LLKS CVLEAFGNA+TNRN NSSRFGKYMDINFDFKGDPIGGH
Sbjct: 121  AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180

Query: 181  INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240
            I++YLLEKSRV+ Q  GER+FH+FYQLL+G  ++ L  LHL+++ + YN+ H GA L  +
Sbjct: 181  IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240

Query: 241  INDAAE-----FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENG- 294
            ++ A +      + V +AM+VIGF PEE+++V++ILAAILHLGN++FV   +  L + G 
Sbjct: 241  VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300

Query: 295  -----KVVSIIAELLSTKTDMVEKALLYRTVATG-RDIIDKQHTEQEASYGRDAFAKAIY 348
                  +V  +AEL +T  D+V ++LL RTVA+G R++I+K HT  EASY RDA AKA+Y
Sbjct: 301  AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY 360

Query: 349  ERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQ 408
            +RLF W+V RIN ++E +  D    GK+TVIGVLDIYGFE+F  NSFEQFCINYCNEKLQ
Sbjct: 361  QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 420

Query: 409  QLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTD 468
            QLFIQL+LKQEQEEY+REGI W+ ++YFNN  IVDLVE+ H+GI+A+LD+AC + G +TD
Sbjct: 421  QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD 480

Query: 469  EMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF 528
             +FL+ L+     H H++SR+LC +DK +EF RDFRI+HYAGDV YSV GFIDKN+D LF
Sbjct: 481  RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540

Query: 529  QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVR 588
            QDFKRL+YNS++P L+ MWP+G+  ITEVTKRPLTA TLFKNSM+ALV+NLASKEP+YVR
Sbjct: 541  QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600

Query: 589  CIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWP 648
            CIKPN+ K     D+  CRHQV YLGLLENVRVRRAGFA RQ Y +FL RYKM  E+TWP
Sbjct: 601  CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660

Query: 649  NHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV 708
            NH L SDK AV  L+E+ G Q DVA+G +K+FIR+PRTL TLE+ RA+++  IVL LQK 
Sbjct: 661  NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720

Query: 709  WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKV 768
            WRGTLAR R +R +A  TI+R++RR+KV++++ E+ RRF   +    YG+ + WP PP V
Sbjct: 721  WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV 780

Query: 769  LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYL 828
            L+ F++    +F RWRA QL+K+IP SD+PQ++AKVAA+  L+G R D G +RAW  +YL
Sbjct: 781  LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL 840

Query: 829  ASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD 888
            +S  D P  S  F      L+ KD +  VLFS HVRKVNRF K+ +RA+ +TD+HLYK+D
Sbjct: 841  SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD 900

Query: 889  PTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGV 948
            P +QY+VM+ +PL  +TGLSV++G DQLVV H +   DL+VCL   +P  ++R+GELVGV
Sbjct: 901  PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV 960

Query: 949  LVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVP 1004
            L  H + E R L+V V++ +  S  G +  +SVE R  QP+PDF   R  F L  P
Sbjct: 961  LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWP 1016


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score =  717 bits (1852), Expect = 0.0
 Identities = 413/1006 (41%), Positives = 584/1006 (58%), Gaps = 112/1006 (11%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL++ ++   F+ NL+ RF+   IYT+IG VV+SVNPY+ L IY  + +E+Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE  PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
           EV +VK  LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
           RV+ Q  GER+FH FYQLL G SE++L  L L++  S YNY+ + +   + ++DAA FR 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253

Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304
           V +AM+++GF   E ++V  ++AA+L LGN++F  +      D   I++   +  I EL 
Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
                ++E+A  +RTV   ++ +       +A Y RDA AK +Y RLF W+V RIN+ I+
Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
            +   T +  K  V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY 
Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
           RE I W HIDYFNN II DL+E    GI+A+LD+ C+  G VTDE FLE LN     H H
Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488

Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537
           F SR      K   F  D       FRI+HYAG V+Y V GF+DKN D L++D  + M+ 
Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544

Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597
           +S+ ++K+++PEG  +   + KRP TA + FK S+  L+ NL +K P Y+RCIKPNDKK+
Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603

Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657
             IF++    HQ+ YLGLLENVRVRRAG+AFRQ YE  L RYKM+ + TWP+   P+ + 
Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662

Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLAR- 715
            V+ L        ++ ++G++KIFIR PRTLF LE+LR Q L  +   +QK++RG   R 
Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722

Query: 716 ----------------------MRYKRTK-AALTIIRYYRRYKVKSYIHE---------- 742
                                  RY++TK +AL I  Y R +K +  + E          
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782

Query: 743 ---VARRFHGVKTMRDYGKHVK------------------------------------WP 763
              +A  +HG +  R+Y K  +                                    WP
Sbjct: 783 VTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWP 842

Query: 764 SPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRA--DLGLQ 820
           S P + L    + L+ IF+ WR  +               K+ A E+ K ++A     + 
Sbjct: 843 SRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVG 902

Query: 821 RAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVT 880
           + ++G YL    +         P   +LK   +   ++ +  V K+NR +      IF+ 
Sbjct: 903 QPFQGAYLEINKN---------PKYKKLKDAIE-EKIIIAEVVNKINRANGKSTSRIFLL 952

Query: 881 DRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKD 926
             +   +   K  ++   +PL ++T +S+S+  D     H K+  +
Sbjct: 953 TNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSE 998


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  705 bits (1820), Expect = 0.0
 Identities = 376/792 (47%), Positives = 515/792 (65%), Gaps = 27/792 (3%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL++ ++   F+ NL+ RF+   IYT+IG VV+SVNPY+ L IY  + +E+Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE  PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
           EV +VK  LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
           RV+ Q  GER+FH FYQLL G SE++L  L L++  S YNY+ + +   + ++DAA FR 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253

Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304
           V +AM+++GF   E ++V  ++AA+L LGN++F  +      D   I++   +  I EL 
Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
                ++E+A  +RTV   ++ +       +A Y RDA AK +Y RLF W+V RIN+ I+
Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
            +   T +  K  V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY 
Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
           RE I W HIDYFNN II DL+E    GI+A+LD+ C+  G VTDE FLE LN     H H
Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488

Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537
           F SR      K   F  D       FRI+HYAG V+Y V GF+DKN D L++D  + M+ 
Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544

Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597
           +S+ ++K+++PEG  +   + KRP TA + FK S+  L+ NL +K P Y+RCIKPNDKK+
Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603

Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657
             IF++    HQ+ YLGLLENVRVRRAG+AFRQ YE  L RYKM+ + TWP+   P+ + 
Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662

Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARM 716
            V+ L        ++ ++G++KIFIR PRTLF LE+LR Q L  +   +QK++RG   R 
Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722

Query: 717 RY-KRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEA 775
            +    K+ + I  +YRRY  +    +       +++     K  K     K  +R +EA
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782

Query: 776 LQTIFNRWRASQ 787
           + TI   W  +Q
Sbjct: 783 VTTIAAYWHGTQ 794



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 47/242 (19%), Positives = 96/242 (39%), Gaps = 24/242 (9%)

Query: 691  EELRAQMLIRIVLFLQKVWRGTLARMRYK---RTKAALTIIRYYRRYKVKSYIHEVARRF 747
            EE R +  + ++      W G   R  Y+   R  A   I  +  +  V+ Y  E+  + 
Sbjct: 833  EEARRKHAVAVIW---AYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKM 889

Query: 748  HGVKTMRDYGKHVKWPSPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAA 806
              +  +        WPS P + L    + L+ IF+ WR  +               K+ A
Sbjct: 890  PSLSPIDK-----NWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEA 944

Query: 807  VEMLKGQRA--DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVR 864
             E+ K ++A     + + ++G YL    +       +  + + ++ K     ++ +  V 
Sbjct: 945  SELFKDKKALYPSSVGQPFQGAYLEINKNPK-----YKKLKDAIEEK-----IIIAEVVN 994

Query: 865  KVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDN 924
            K+NR +      IF+   +   +   K  ++   +PL ++T +S+S+  D     H K+ 
Sbjct: 995  KINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEG 1054

Query: 925  KD 926
             +
Sbjct: 1055 SE 1056


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  705 bits (1820), Expect = 0.0
 Identities = 376/792 (47%), Positives = 515/792 (65%), Gaps = 27/792 (3%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL++ ++   F+ NL+ RF+   IYT+IG VV+SVNPY+ L IY  + +E+Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE  PH+FA++D AY++++ + KD CI+I+GESGAGKTEASK +M Y+AA+      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
           EV +VK  LL+SN VLEAFGNAKT RNDNSSRFGKYMDI FDFKGDP+GG I+NYLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
           RV+ Q  GER+FH FYQLL G SE++L  L L++  S YNY+ + +   + ++DAA FR 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRT 253

Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDG-----DTPLIENGKVVSIIAELL 304
           V +AM+++GF   E ++V  ++AA+L LGN++F  +      D   I++   +  I EL 
Sbjct: 254 VRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELT 313

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
                ++E+A  +RTV   ++ +       +A Y RDA AK +Y RLF W+V RIN+ I+
Sbjct: 314 GIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIK 373

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
            +   T +  K  V+GVLDIYGFEIF++NSFEQF INYCNEKLQQ+FI+L LK+EQEEY 
Sbjct: 374 AQ---TKVRKK--VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYI 428

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
           RE I W HIDYFNN II DL+E    GI+A+LD+ C+  G VTDE FLE LN     H H
Sbjct: 429 REDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQH 488

Query: 485 FSSRKLCASDKILEFDRD-------FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYN 537
           F SR      K   F  D       FRI+HYAG V+Y V GF+DKN D L++D  + M+ 
Sbjct: 489 FESR----MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWK 544

Query: 538 SSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKS 597
           +S+ ++K+++PEG  +   + KRP TA + FK S+  L+ NL +K P Y+RCIKPNDKK+
Sbjct: 545 ASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKA 603

Query: 598 PQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKE 657
             IF++    HQ+ YLGLLENVRVRRAG+AFRQ YE  L RYKM+ + TWP+   P+ + 
Sbjct: 604 AHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPA-RS 662

Query: 658 AVKKLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARM 716
            V+ L        ++ ++G++KIFIR PRTLF LE+LR Q L  +   +QK++RG   R 
Sbjct: 663 GVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722

Query: 717 RY-KRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEA 775
            +    K+ + I  +YRRY  +    +       +++     K  K     K  +R +EA
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEA 782

Query: 776 LQTIFNRWRASQ 787
           + TI   W  +Q
Sbjct: 783 VTTIAAYWHGTQ 794



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 47/242 (19%), Positives = 96/242 (39%), Gaps = 24/242 (9%)

Query: 691  EELRAQMLIRIVLFLQKVWRGTLARMRYK---RTKAALTIIRYYRRYKVKSYIHEVARRF 747
            EE R +  + ++      W G   R  Y+   R  A   I  +  +  V+ Y  E+  + 
Sbjct: 833  EEARRKHAVAVIW---AYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKM 889

Query: 748  HGVKTMRDYGKHVKWPSPPKV-LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAA 806
              +  +        WPS P + L    + L+ IF+ WR  +               K+ A
Sbjct: 890  PSLSPIDK-----NWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEA 944

Query: 807  VEMLKGQRA--DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVR 864
             E+ K ++A     + + ++G YL    +       +  + + ++ K     ++ +  V 
Sbjct: 945  SELFKDKKALYPSSVGQPFQGAYLEINKNPK-----YKKLKDAIEEK-----IIIAEVVN 994

Query: 865  KVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDN 924
            K+NR +      IF+   +   +   K  ++   +PL ++T +S+S+  D     H K+ 
Sbjct: 995  KINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEG 1054

Query: 925  KD 926
             +
Sbjct: 1055 SE 1056


>gi|124494247 myosin IC isoform b [Homo sapiens]
          Length = 1044

 Score =  697 bits (1800), Expect = 0.0
 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%)

Query: 10  GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G  DFVL++   S   F+ NLR RF +  IYT+IG V+VSVNPY+ L IY R  +E+Y+G
Sbjct: 28  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
              YE PPHLFA+AD  Y+A++   +D  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 88  VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
                V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK
Sbjct: 148 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 205

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247
           SRV+ Q  GER+FH FYQLL+GG E+ LR L L+++  SY Y+  G   K SSIND +++
Sbjct: 206 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 265

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306
           +VV  A+ VI F  +E++ +  I+A++LHLGN+ F  + ++   +     +  +  LLS 
Sbjct: 266 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 325

Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
           +   + +AL +R + A G +++   + EQ A+Y RDA AKA+Y R F W+V +IN  +  
Sbjct: 326 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 384

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
           K+ ++      TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ 
Sbjct: 385 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 444

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485
           EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+  G+ TD  FLE L   +  H HF
Sbjct: 445 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 504

Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
            + KL          R +FR+ HYAG+V YSV GF+DKN D LF++ K  M +S NP++ 
Sbjct: 505 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 564

Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604
             +   +LS     KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P  FD+ 
Sbjct: 565 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 621

Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663
             RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK +   TWP     P D  AV  L+
Sbjct: 622 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 679

Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699
              G++ ++   G+TKIFIR P+TLF  E   E+R Q L                     
Sbjct: 680 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 739

Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750
           R  + +Q  WRGTL R +  KR  AA TI R  R + ++        ++  +  R    +
Sbjct: 740 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 799

Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807
              R   ++V    WP+PP  LR   E L+ +  +    +  +SI      Q++ K  A 
Sbjct: 800 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 859

Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867
           E+ KG++ +    ++    +++++  T + S   +              + ++  V K +
Sbjct: 860 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 910

Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924
           R   K   R + +T   +  ++     KV + I   NLTG+SVS+  D L V H +  DN
Sbjct: 911 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 967

Query: 925 K 925
           K
Sbjct: 968 K 968


>gi|124494238 myosin IC isoform a [Homo sapiens]
          Length = 1063

 Score =  697 bits (1800), Expect = 0.0
 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%)

Query: 10  GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G  DFVL++   S   F+ NLR RF +  IYT+IG V+VSVNPY+ L IY R  +E+Y+G
Sbjct: 47  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
              YE PPHLFA+AD  Y+A++   +D  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
                V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK
Sbjct: 167 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247
           SRV+ Q  GER+FH FYQLL+GG E+ LR L L+++  SY Y+  G   K SSIND +++
Sbjct: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 284

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306
           +VV  A+ VI F  +E++ +  I+A++LHLGN+ F  + ++   +     +  +  LLS 
Sbjct: 285 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 344

Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
           +   + +AL +R + A G +++   + EQ A+Y RDA AKA+Y R F W+V +IN  +  
Sbjct: 345 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 403

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
           K+ ++      TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ 
Sbjct: 404 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 463

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485
           EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+  G+ TD  FLE L   +  H HF
Sbjct: 464 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 523

Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
            + KL          R +FR+ HYAG+V YSV GF+DKN D LF++ K  M +S NP++ 
Sbjct: 524 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 583

Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604
             +   +LS     KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P  FD+ 
Sbjct: 584 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 640

Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663
             RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK +   TWP     P D  AV  L+
Sbjct: 641 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 698

Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699
              G++ ++   G+TKIFIR P+TLF  E   E+R Q L                     
Sbjct: 699 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 758

Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750
           R  + +Q  WRGTL R +  KR  AA TI R  R + ++        ++  +  R    +
Sbjct: 759 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 818

Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807
              R   ++V    WP+PP  LR   E L+ +  +    +  +SI      Q++ K  A 
Sbjct: 819 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 878

Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867
           E+ KG++ +    ++    +++++  T + S   +              + ++  V K +
Sbjct: 879 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 929

Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924
           R   K   R + +T   +  ++     KV + I   NLTG+SVS+  D L V H +  DN
Sbjct: 930 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 986

Query: 925 K 925
           K
Sbjct: 987 K 987


>gi|124494240 myosin IC isoform c [Homo sapiens]
          Length = 1028

 Score =  697 bits (1800), Expect = 0.0
 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%)

Query: 10  GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G  DFVL++   S   F+ NLR RF +  IYT+IG V+VSVNPY+ L IY R  +E+Y+G
Sbjct: 12  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
              YE PPHLFA+AD  Y+A++   +D  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 72  VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
                V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK
Sbjct: 132 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 189

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247
           SRV+ Q  GER+FH FYQLL+GG E+ LR L L+++  SY Y+  G   K SSIND +++
Sbjct: 190 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 249

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306
           +VV  A+ VI F  +E++ +  I+A++LHLGN+ F  + ++   +     +  +  LLS 
Sbjct: 250 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 309

Query: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
           +   + +AL +R + A G +++   + EQ A+Y RDA AKA+Y R F W+V +IN  +  
Sbjct: 310 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 368

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
           K+ ++      TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ 
Sbjct: 369 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 428

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485
           EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+  G+ TD  FLE L   +  H HF
Sbjct: 429 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 488

Query: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
            + KL          R +FR+ HYAG+V YSV GF+DKN D LF++ K  M +S NP++ 
Sbjct: 489 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 548

Query: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604
             +   +LS     KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P  FD+ 
Sbjct: 549 QCFDRSELS---DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 605

Query: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLI 663
             RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK +   TWP     P D  AV  L+
Sbjct: 606 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 663

Query: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699
              G++ ++   G+TKIFIR P+TLF  E   E+R Q L                     
Sbjct: 664 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 723

Query: 700 RIVLFLQKVWRGTLARMR-YKRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750
           R  + +Q  WRGTL R +  KR  AA TI R  R + ++        ++  +  R    +
Sbjct: 724 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 783

Query: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807
              R   ++V    WP+PP  LR   E L+ +  +    +  +SI      Q++ K  A 
Sbjct: 784 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 843

Query: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867
           E+ KG++ +    ++    +++++  T + S   +              + ++  V K +
Sbjct: 844 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 894

Query: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924
           R   K   R + +T   +  ++     KV + I   NLTG+SVS+  D L V H +  DN
Sbjct: 895 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 951

Query: 925 K 925
           K
Sbjct: 952 K 952


>gi|4885503 myosin IA [Homo sapiens]
          Length = 1043

 Score =  690 bits (1780), Expect = 0.0
 Identities = 400/973 (41%), Positives = 575/973 (59%), Gaps = 81/973 (8%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL++ +     + NL+LR+E   IYT+IG VV+SVNPY+ L IYG + I +Y+  
Sbjct: 9   GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE  PH++A+A+ AY++++ R +D CI+I+GESG+GKTEASK +M Y+AA+    +  
Sbjct: 69  TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE-- 126

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
           +V  VK  LL+SN VLEAFGNAKT RN+NSSRFGKYMDI FDFKG P+GG I NYLLEKS
Sbjct: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
           R++ Q  GER+FH FYQLL G  EQ+L++L L++  + Y Y++        ++DA+ FR 
Sbjct: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVSRVDGMDDASSFRA 246

Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNL----KFVVDG-DTPLIENGKVVSIIAELL 304
           V  AM VIGF  EEI+ V ++ + +L LGN+    +F   G     I +G+ V  I E++
Sbjct: 247 VQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMV 306

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
              ++ VE+AL  RT+ T ++ +       +A Y RDA AK IY RLF WIV RIN+ I+
Sbjct: 307 GLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESIK 366

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
           V      I  K  V+GVLDIYGFEI ++NSFEQF INYCNEKLQQ+FI++ LK+EQEEY+
Sbjct: 367 V-----GIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYK 421

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
           REGIPW  +DYF+N II  L+E   +GI+A+LD+ C+  G V+D  FL  LN    KH H
Sbjct: 422 REGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGH 481

Query: 485 FSSRKLCASDKILEFDRD-----FRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539
           + S+    + +  ++D       FRI HYAG V Y+V  FIDKN D LF+D  + M+ + 
Sbjct: 482 YESKVTQNAQR--QYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539

Query: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599
           +P+L++++PEG      + KRP TA   FK+S+  L+ NL SK P Y+RCIKPN+ +   
Sbjct: 540 HPLLRSLFPEGNPKQASL-KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRG 598

Query: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659
            F  +    Q  YLGLLENVRVRRAG+A RQ Y  FL RY+++S  TWP H    D+E V
Sbjct: 599 QFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWP-HWNGGDREGV 657

Query: 660 KKLIERCGFQD-DVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718
           +K++        ++A+GKTKIFIR+P+TLF LEE R   L ++   +QK++RG   R  Y
Sbjct: 658 EKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHY 717

Query: 719 KRTKAALTIIRYYRR--------YKVKSYIHEVARRFHGVKTMRDYGKHVK--------- 761
           +  + +  +I  + R         K+K+ +  +     G K  ++Y K+ +         
Sbjct: 718 QLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLAD 777

Query: 762 ---------------------------WPSPP-KVLRRFEEALQTIFNRWRASQLIKSIP 793
                                      WP+ P K L    + LQ +F +W+  +    + 
Sbjct: 778 FIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLS 837

Query: 794 ASDLPQVRAKVAAVEMLKGQRADL--GLQRAWEGNYLASKPDTPQTSGTFVPVANELKRK 851
              +  +R K+ A E+ KG++A     +   + G+Y+  + +         P   +LK  
Sbjct: 838 PKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGN---------PKLQKLKGG 888

Query: 852 DKYMNVLFSCHVRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVS 910
           ++   VL +  V+KVNR + K   R + +T  H+   D TK+ +    I L N+ G+SV+
Sbjct: 889 EE-GPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTD-TKKSQAKIVIGLDNVAGVSVT 946

Query: 911 NGKDQLVVFHTKD 923
           + KD L   H  +
Sbjct: 947 SLKDGLFSLHLSE 959


>gi|254028267 myosin 1H [Homo sapiens]
          Length = 1022

 Score =  667 bits (1721), Expect = 0.0
 Identities = 423/1048 (40%), Positives = 597/1048 (56%), Gaps = 107/1048 (10%)

Query: 10   GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
            G  DFVL+D   S   F+ NLR RF +  IYT+IG ++VSVNPY+ L IY    +E Y+G
Sbjct: 12   GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71

Query: 69   RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
               +E PPH++AIAD AY+ M     +  I+ISGESGAGKTEASK I++Y A     +Q 
Sbjct: 72   VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131

Query: 129  AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
             ++ R  + LL SN VLEAFGNA+T RNDNSSRFGKYMDI FDF+G P+GGHI +YL+EK
Sbjct: 132  LQIAR--DRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189

Query: 189  SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247
            SRV+ Q  GER+FH FYQLL GG E+ L  L L++    Y Y+  G   K SSI+D  ++
Sbjct: 190  SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249

Query: 248  RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGD-TPLIENGKVVSIIAELLST 306
            + V++A  VI F   +++ ++ I+A++LHLGN+ F  D      I +   +  IA+LL  
Sbjct: 250  KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGV 309

Query: 307  KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366
               ++ +AL +R +    + +    T + + Y RDA AKA+Y R F W+V +IN  +  K
Sbjct: 310  HPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNK 369

Query: 367  NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426
            ++      + TVIG+LDIYGFE+FD N FEQFCINYCNEKLQQL I+  LK EQ EY+ E
Sbjct: 370  DFT-----RKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEME 424

Query: 427  GIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFS 486
            GI W+ I YFNN+II DLVE++HKGII+ILD+ C+  G  TD  FLE L  K+GKHAHF 
Sbjct: 425  GIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFE 484

Query: 487  SRKLCASDKILEFD-RDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKN 545
            +RKL            +FR+ HYAG+V Y   GF++KN D L++  K ++  S N +L+ 
Sbjct: 485  TRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544

Query: 546  MWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDER 605
             +    L+  E  +RP T  T FKNS+ +L++ L SKEP Y+RCIKPND+K P  FDD  
Sbjct: 545  CF---LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFL 601

Query: 606  CRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLIE 664
             RHQ++YLGL+E++RVRRAGFA+R+ YE FL RYK +   TWP+ H  P+  E V++LI+
Sbjct: 602  IRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPA--EGVERLIK 659

Query: 665  RCGFQ-DDVAYGKTKIFIRTPRTLFTLEEL----RAQMLIRI------------------ 701
              G++ ++   GKTKIFIR PRTLF  E+     + Q++ RI                  
Sbjct: 660  YIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQ 719

Query: 702  -VLFLQKVWRGTLARMRYKRTKAALTIIRYYRR------------------YKVKSYIHE 742
              + L+  WRG LAR   +R K A+ IIR + +                  +  K+YI  
Sbjct: 720  AAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILN 779

Query: 743  VARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRA 802
            +  R+H  KT+ D      W  PP +L    + L+ +  R    +  + I A     ++ 
Sbjct: 780  L--RYHLPKTVLD----KSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQ 833

Query: 803  KVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCH 862
            KV   E+ +G++   G   +    ++ S+ D     G   P   +L   +K   + +   
Sbjct: 834  KVVTSEIFRGRKD--GYTESLNQPFVNSRID----EGDINPKVLQLISHEK---IQYGVP 884

Query: 863  VRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHT 921
            V K +R   K   R + +T +  Y ++     K+ + I    L G+S SN  D ++V H 
Sbjct: 885  VIKYDRKGFKARQRQLILTQKAAYVVELA---KIKQKIEYSALKGVSTSNLSDGILVIHV 941

Query: 922  --KDNKD----LIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLH-- 973
              +D+K     ++ C           + E V  LV   K E      N+ N VQ SL   
Sbjct: 942  SPEDSKQKGDAVLQC---------GHVFEAVTKLVMLVKKE------NIVNVVQGSLQFF 986

Query: 974  ---GKKCTVSVETRLNQPQPDFTKNRSG 998
               GK+ T+  +T L +      KN++G
Sbjct: 987  ISPGKEGTIVFDTGLEE---QVYKNKNG 1011


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score =  564 bits (1453), Expect = e-160
 Identities = 308/720 (42%), Positives = 448/720 (62%), Gaps = 35/720 (4%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL+  ++    + NL+ R+    I+T+IG V++SVNP+K +  +G   IE Y+G 
Sbjct: 20  GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE PPH++A+AD  Y+ M    ++ C++ISGESGAGKT A+KYIM YI+ ++    + 
Sbjct: 80  AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK- 138

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F   G+P GG I+N+LLEKS
Sbjct: 139 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEFR 248
           RV+++ PGERSFH FYQL++G S +   SL +  S+  Y Y+ +    K   I+D  EF+
Sbjct: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQ 256

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKT 308
               AM VIG   EE   V +I+A ILHLGN+ F   G+   +E+ + ++  A LL    
Sbjct: 257 ETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQ 316

Query: 309 DMVEKALLYRTVAT----GRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
           D +++ L  R + +      + I      ++A Y RDA AKA++ R+F ++V  IN  +E
Sbjct: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
             + +         IGVLDIYGFEIF  N FEQFCIN+ NEKLQQ+FI+L LK EQEEY 
Sbjct: 377 KDHEEYN-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYV 429

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMN---VGKVTDEMFLEALNSKL 479
           +EGI W  I+YFNN+I+ DL+E +    GI++ILDD C     VG+  D+  L+ L  ++
Sbjct: 430 QEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQI 489

Query: 480 GKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539
           G H HF+S           +++ F I HYAG V Y + GF ++N+D LF D   LM +S 
Sbjct: 490 GSHEHFNS-----------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSE 538

Query: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599
            P +K+++PE   +  +   RP TA +  K     LV  L    P+Y+RCIKPN+ K P+
Sbjct: 539 LPFIKSLFPENLQA--DKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596

Query: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659
            +++ R +HQVEYLGL EN+RVRRAG+A+R+ ++KFL RY ++++ TWP+     +K+ V
Sbjct: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQ-GEEKQGV 655

Query: 660 KKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718
             L++      D    G++K+FI+ P +LF LEE+R +        +QK WR  +AR +Y
Sbjct: 656 LHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKY 715


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score =  539 bits (1388), Expect = e-153
 Identities = 302/742 (40%), Positives = 446/742 (60%), Gaps = 33/742 (4%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D VL+  ++     ANLR RF    I+T+IG V++SVNP+K +  +    I+ Y+G 
Sbjct: 18  GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
             YE PPH++A+ D  Y+ M    ++ C++ISGESGAGKT A+KYIM YI+ ++   ++ 
Sbjct: 78  AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK- 136

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F   G+P GG I+N+LLEKS
Sbjct: 137 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRV 249
           RV++Q   ER+FH +YQLL+G S++  ++L L      Y             +D ++F  
Sbjct: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGE 255

Query: 250 VADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTD 309
              AM+VIG  P   Q V +++A ILHLGN+ F  DG+   +E+  +++  A LL   + 
Sbjct: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESVDLLAFPAYLLGIDSG 315

Query: 310 MVEKALLYRTVAT---GR-DIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
            +++ L  R + +   GR + I+     ++A+Y RDA AK +Y RLF ++V  IN  ++ 
Sbjct: 316 RLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQK 375

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
              + +       IGVLDIYGFEIF  N FEQFCIN+ NEKLQQ+FI+L LK EQEEY +
Sbjct: 376 PQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQ 428

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMNV---GKVTDEMFLEALNSKLG 480
           EGI W  I YFNN+++ DL+E +    GI+++LDD C  +   G   D+  L+ L + +G
Sbjct: 429 EGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVG 488

Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540
            H HF+S           +   F I HYAG V Y V GF ++N+D LF D   LM  S  
Sbjct: 489 THEHFNS-----------WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQ 537

Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600
             L+ ++PE KL   +   RP TA +  K     LV  L    P+Y+RCIKPN+ K P+ 
Sbjct: 538 AFLRMLFPE-KLD-GDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRD 595

Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660
           +++ R +HQVEYLGL EN+RVRRAGFA+R+ + KFL RY +++  TWP      +++ V+
Sbjct: 596 WEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRW-RGDERQGVQ 654

Query: 661 KLIERCGFQ-DDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719
            L+     + D    G TK+F++ P +LF LEE+R +        +QK WR  +A  +Y+
Sbjct: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714

Query: 720 RTKAALTIIRYYRRYKVKSYIH 741
             +   + I   ++ + ++ I+
Sbjct: 715 EMREEASNILLNKKERRRNSIN 736


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  478 bits (1229), Expect = e-134
 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D + +  ++    + NL +R+    IYT+ G ++V+VNPY+LL+IY  + I QY  +
Sbjct: 66  GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
           ++ E PPH+FAIAD  Y  MKR S+D C +ISGESGAGKTE++K I+Q++AAI+   Q +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            +E+    +L++  +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G   G  I  YLLEKS
Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248
           RV  Q   ER++H FY +L+G SE   + L L ++ S YNY+ +G  +      D+ E+ 
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300
            +  AMKV+ F   E   + K+LAAILHLGNL++    +    EN     ++        
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355

Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360
           A LL      +   L  RT+ T  + +    + ++A   RDAF K IY RLF WIV +IN
Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415

Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420
             I  K     +      IG+LDI+GFE F  NSFEQ CIN+ NE LQQ F++ V K EQ
Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474

Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480
           EEY  E I W HI++ +NQ  +D++  +   II+++D+      K TD   L  LNS+  
Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533

Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540
            +A++   K          +  F I H+AG V Y   GF++KN+DTL  D  +L+++S N
Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586

Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600
             +K ++        E  KR  T ++ FK S+  L+  L + +P++VRCIKPN+ K P +
Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660
           FD   C  Q+ Y G++E +R+RRAG+  R ++ +F+ RY+++     P +     +   +
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719
           ++ E   G  DD   GKTKIF++    +  LE  R + +   V+ LQKV RG   R  + 
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765

Query: 720 RTKAALTIIRYYRR 733
           + K A T+I+ + R
Sbjct: 766 KLKNAATLIQRHWR 779


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  478 bits (1229), Expect = e-134
 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D + +  ++    + NL +R+    IYT+ G ++V+VNPY+LL+IY  + I QY  +
Sbjct: 66  GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
           ++ E PPH+FAIAD  Y  MKR S+D C +ISGESGAGKTE++K I+Q++AAI+   Q +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            +E+    +L++  +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G   G  I  YLLEKS
Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248
           RV  Q   ER++H FY +L+G SE   + L L ++ S YNY+ +G  +      D+ E+ 
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300
            +  AMKV+ F   E   + K+LAAILHLGNL++    +    EN     ++        
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355

Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360
           A LL      +   L  RT+ T  + +    + ++A   RDAF K IY RLF WIV +IN
Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415

Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420
             I  K     +      IG+LDI+GFE F  NSFEQ CIN+ NE LQQ F++ V K EQ
Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474

Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480
           EEY  E I W HI++ +NQ  +D++  +   II+++D+      K TD   L  LNS+  
Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533

Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540
            +A++   K          +  F I H+AG V Y   GF++KN+DTL  D  +L+++S N
Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586

Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600
             +K ++        E  KR  T ++ FK S+  L+  L + +P++VRCIKPN+ K P +
Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660
           FD   C  Q+ Y G++E +R+RRAG+  R ++ +F+ RY+++     P +     +   +
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719
           ++ E   G  DD   GKTKIF++    +  LE  R + +   V+ LQKV RG   R  + 
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765

Query: 720 RTKAALTIIRYYRR 733
           + K A T+I+ + R
Sbjct: 766 KLKNAATLIQRHWR 779


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  478 bits (1229), Expect = e-134
 Identities = 285/734 (38%), Positives = 423/734 (57%), Gaps = 30/734 (4%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D + +  ++    + NL +R+    IYT+ G ++V+VNPY+LL+IY  + I QY  +
Sbjct: 66  GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
           ++ E PPH+FAIAD  Y  MKR S+D C +ISGESGAGKTE++K I+Q++AAI+   Q +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG--QHS 183

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            +E+    +L++  +LEAFGNAKT RNDNSSRFGKY+DI+F+ +G   G  I  YLLEKS
Sbjct: 184 WIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN-DAAEFR 248
           RV  Q   ER++H FY +L+G SE   + L L ++ S YNY+ +G  +      D+ E+ 
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQA-SDYNYLAMGNCITCEGRVDSQEYA 299

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSII-------- 300
            +  AMKV+ F   E   + K+LAAILHLGNL++    +    EN     ++        
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY----EARTFENLDACEVLFSPSLATA 355

Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360
           A LL      +   L  RT+ T  + +    + ++A   RDAF K IY RLF WIV +IN
Sbjct: 356 ASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKIN 415

Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420
             I  K     +      IG+LDI+GFE F  NSFEQ CIN+ NE LQQ F++ V K EQ
Sbjct: 416 AAI-YKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQ 474

Query: 421 EEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLG 480
           EEY  E I W HI++ +NQ  +D++  +   II+++D+      K TD   L  LNS+  
Sbjct: 475 EEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEES-KFPKGTDTTMLHKLNSQHK 533

Query: 481 KHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSN 540
            +A++   K          +  F I H+AG V Y   GF++KN+DTL  D  +L+++S N
Sbjct: 534 LNANYIPPKN-------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRN 586

Query: 541 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQI 600
             +K ++        E  KR  T ++ FK S+  L+  L + +P++VRCIKPN+ K P +
Sbjct: 587 KFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPML 646

Query: 601 FDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVK 660
           FD   C  Q+ Y G++E +R+RRAG+  R ++ +F+ RY+++     P +     +   +
Sbjct: 647 FDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQ 706

Query: 661 KLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYK 719
           ++ E   G  DD   GKTKIF++    +  LE  R + +   V+ LQKV RG   R  + 
Sbjct: 707 RMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKDRSNFL 765

Query: 720 RTKAALTIIRYYRR 733
           + K A T+I+ + R
Sbjct: 766 KLKNAATLIQRHWR 779


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  471 bits (1213), Expect = e-132
 Identities = 290/764 (37%), Positives = 438/764 (57%), Gaps = 59/764 (7%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G+ D   +  +  P  + NLR+RF   + IYT+ G V+V++NPY+ L IYG D I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
           + + +  PH+FA+A+ AYK M R  ++  I++SGESGAGKT ++KY M+Y A ++  +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
           A VE     +L SN ++E+ GNAKT RNDNSSRFGKY++I FD +   IG ++  YLLEK
Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYI-HVGAQLKSSINDAAEF 247
           SRV+ Q   ER++H FYQL         + L L  +  ++NY    G+ +   ++DA E 
Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNA-DNFNYTKQGGSPVIEGVDDAKEM 305

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV-DGDTPLI-ENGKVVSIIAELLS 305
                A  ++G        +++ILA ILHLGN+ F   D D+  I    + + I  +L+ 
Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365

Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
              + +   L +R +AT  +   K  ++ +A+  RDA AK IY +LF WIV  +N  +  
Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH- 424

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
                +   +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F   V K EQEEY +
Sbjct: 425 -----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484
           E IPW  ID+++NQ  ++L+E +  GI+ +LD+ C  + K TD+ + + L N+ L K A 
Sbjct: 480 EQIPWTLIDFYDNQPCINLIESK-LGILDLLDEEC-KMPKGTDDTWAQKLYNTHLNKCAL 537

Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
           F   +L         ++ F I+H+A  V Y   GF++KNKDT+F++  +++ +S   +L 
Sbjct: 538 FEKPRLS--------NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589

Query: 545 NMWPEGKLSI----------TEVTKRPL----------------TAATLFKNSMIALVDN 578
            ++ + + +I          T +T+ P                 T    F+NS+  L++ 
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649

Query: 579 LASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHR 638
           L +  P+YVRCIKPND K P  FD++R   Q+   G+LE +R+  AGF  R TY++F  R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709

Query: 639 YKMISEFTWPNHDLPSD-KEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQ 696
           Y+++ +      D+ SD K+  K ++E+    +D   +GKTKIF R  +  + LE+LRA 
Sbjct: 710 YRVLMK----QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764

Query: 697 MLIRIVLFLQKVWRGTLARMRYKR-TKAALTIIRYYRRYKVKSY 739
            L    + +QK  RG L R +Y R  KAA+T+ RY R Y+ + Y
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  471 bits (1213), Expect = e-132
 Identities = 290/764 (37%), Positives = 438/764 (57%), Gaps = 59/764 (7%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G+ D   +  +  P  + NLR+RF   + IYT+ G V+V++NPY+ L IYG D I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
           + + +  PH+FA+A+ AYK M R  ++  I++SGESGAGKT ++KY M+Y A ++  +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
           A VE     +L SN ++E+ GNAKT RNDNSSRFGKY++I FD +   IG ++  YLLEK
Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYI-HVGAQLKSSINDAAEF 247
           SRV+ Q   ER++H FYQL         + L L  +  ++NY    G+ +   ++DA E 
Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNA-DNFNYTKQGGSPVIEGVDDAKEM 305

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV-DGDTPLI-ENGKVVSIIAELLS 305
                A  ++G        +++ILA ILHLGN+ F   D D+  I    + + I  +L+ 
Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365

Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
              + +   L +R +AT  +   K  ++ +A+  RDA AK IY +LF WIV  +N  +  
Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH- 424

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
                +   +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F   V K EQEEY +
Sbjct: 425 -----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484
           E IPW  ID+++NQ  ++L+E +  GI+ +LD+ C  + K TD+ + + L N+ L K A 
Sbjct: 480 EQIPWTLIDFYDNQPCINLIESK-LGILDLLDEEC-KMPKGTDDTWAQKLYNTHLNKCAL 537

Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
           F   +L         ++ F I+H+A  V Y   GF++KNKDT+F++  +++ +S   +L 
Sbjct: 538 FEKPRLS--------NKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589

Query: 545 NMWPEGKLSI----------TEVTKRPL----------------TAATLFKNSMIALVDN 578
            ++ + + +I          T +T+ P                 T    F+NS+  L++ 
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649

Query: 579 LASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHR 638
           L +  P+YVRCIKPND K P  FD++R   Q+   G+LE +R+  AGF  R TY++F  R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709

Query: 639 YKMISEFTWPNHDLPSD-KEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQ 696
           Y+++ +      D+ SD K+  K ++E+    +D   +GKTKIF R  +  + LE+LRA 
Sbjct: 710 YRVLMK----QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764

Query: 697 MLIRIVLFLQKVWRGTLARMRYKR-TKAALTIIRYYRRYKVKSY 739
            L    + +QK  RG L R +Y R  KAA+T+ RY R Y+ + Y
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  469 bits (1206), Expect = e-132
 Identities = 285/751 (37%), Positives = 426/751 (56%), Gaps = 54/751 (7%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGR-IYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G+ D   +  +  P  + NLR+RF + + IYT+ G ++V++NPYK L IYG   I  Y G
Sbjct: 68  GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
           + + +  PH+FA+A+ AYK M R +++  I++SGESGAGKT +++Y M+Y A ++     
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
           A VE   + +L SN + EA GNAKT RNDNSSRFGKY +I+FD +   IG +++ YLLEK
Sbjct: 188 AHVE---DKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQ-LKSSINDAAEF 247
           SRV+ Q   ER++H FYQL     +   + L L  S   +NY  +G   +   +ND AE 
Sbjct: 245 SRVVFQSENERNYHIFYQLCASAQQSEFKHLKLG-SAEEFNYTRMGGNTVIEGVNDRAEM 303

Query: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGD--TPLIENGKVVSIIAELLS 305
                   ++GFK +    V+KILAAILHLGN++    G+  + + E+   + +  ELL 
Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLG 363

Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
            ++  V + L  R + T  + + K  T  +A   RDA AK IY  LF +IV RIN  ++ 
Sbjct: 364 LESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQF 423

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
                    ++T IGVLDIYGFE FD NSFEQFCINY NEKLQQ F   V K EQEEY +
Sbjct: 424 SGK------QHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKHAH 484
           E IPW  ID+++NQ ++DL+E +  GI+ +LD+ C+ +   TDE +L+ L N+ + ++  
Sbjct: 478 EDIPWTLIDFYDNQPVIDLIEAK-MGILELLDEECL-LPHGTDENWLQKLYNNFVNRNPL 535

Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
           F   ++         +  F I+H+A  V Y   GF++KN+DT++     ++  S   +  
Sbjct: 536 FEKPRMS--------NTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCA 587

Query: 545 NMW--------PEGKLSITEVTKRPL---------TAATLFKNSMIALVDNLASKEPYYV 587
           N +        P G +   +  K+ +         T  + F++S+  L++ L +  P+YV
Sbjct: 588 NFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYV 647

Query: 588 RCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI---SE 644
           RCIKPND+K P  FD +R   Q+   G+LE +R+    +  R TY +F  RY ++    E
Sbjct: 648 RCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQE 707

Query: 645 FTWPNHDLPSDKEAVKKLIERCGFQDDVAY--GKTKIFIRTPRTLFTLEELRAQMLIRIV 702
            ++      SDK+ V K++     QD   Y  GKTKIF R  +  + LE+LR   L +  
Sbjct: 708 LSF------SDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAY-LEKLRLDKLRQSC 760

Query: 703 LFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733
           + +QK  RG L R ++ R + A  II+ Y R
Sbjct: 761 VMVQKHMRGWLQRKKFLRERRAALIIQQYFR 791


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  459 bits (1182), Expect = e-129
 Identities = 274/757 (36%), Positives = 438/757 (57%), Gaps = 45/757 (5%)

Query: 8    EFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYK 67
            E G  D   ++ +     ++NL++RFE+  IYT+IG ++VSVNPY++  IYG + ++QY 
Sbjct: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYN 1280

Query: 68   GRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQ 127
            GR L E PPHLFA+A+ A+  M    ++ CI+ISGESG+GKTEA+K I++Y+AA+    +
Sbjct: 1281 GRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN--QK 1338

Query: 128  RAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI-NNYLL 186
            R  ++++K  +L++  +LE+FGNAKT RNDNSSRFGK+++I  +  G  I G I + YLL
Sbjct: 1339 REVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLL 1394

Query: 187  EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAA 245
            EKSR++ Q   ER++H FY+LL G   Q+ ++  LQ++  +Y Y++ G   + +  +DA 
Sbjct: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEA-ETYYYLNQGGNCEIAGKSDAD 1453

Query: 246  EFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNL---KFVVDG-DTPLIENGKVVSIIA 301
            +FR +  AM+V+GF  E+  ++++ILA+ILHLGN+   K+  D  +   + + + +  +A
Sbjct: 1454 DFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVA 1513

Query: 302  ELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIND 361
            ELL    + ++KA+ ++   T R+ I    T + A   RDA AK +Y  LF W++TR+N 
Sbjct: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573

Query: 362  IIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQE 421
            ++  +  DT        I +LDIYGFE    NSFEQ CINY NE LQ LF ++V ++EQE
Sbjct: 1574 LVSPRQ-DT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQE 1626

Query: 422  EYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGK 481
            EY RE I W+ I + +NQ  ++L+  +  GI+ ILDD C    + TD  FL+  +   G 
Sbjct: 1627 EYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCC-FPQATDHTFLQKCHYHHGA 1685

Query: 482  HAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNP 541
            +  +S  K+           +F I+HYAG V Y V  F+DKN D + QD   L   S   
Sbjct: 1686 NPLYSKPKMPLP--------EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTR 1737

Query: 542  VLKNMWPE----------GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIK 591
            V+ +++            GK S      +  T A  F+ S++ LV+ +    P ++RC+K
Sbjct: 1738 VVAHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLK 1797

Query: 592  PNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHD 651
            PN KK P +F+ +    Q+ Y G+LE VR+R+ GF  R  ++ F+ RY  +       HD
Sbjct: 1798 PNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVAL---KHD 1854

Query: 652  LPSDKEAVKKLIER-CGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVW 709
            LP++ +    ++ R C    ++   G +K+F++       LE +R  +L    L LQ+  
Sbjct: 1855 LPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK-EHLYQLLESMREHVLNLAALTLQRCL 1913

Query: 710  RGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARR 746
            RG   + R++  +  + +++   R  +    ++  RR
Sbjct: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRR 1950


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  451 bits (1161), Expect = e-126
 Identities = 281/757 (37%), Positives = 426/757 (56%), Gaps = 54/757 (7%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
           G  D + +  ++    + NL +R+++ +IYT+ G ++V+VNP+++L +Y  + ++ Y  R
Sbjct: 66  GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125

Query: 70  ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
            + E PPH+FAIA+  Y +MKR  +D C +ISGESGAGKTE +K I+Q++A I+   Q +
Sbjct: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS--GQHS 183

Query: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
            +E+    +L++N +LEAFGNAKT RNDNSSRFGKY+DI F+  G   G  I  +LLEKS
Sbjct: 184 WIEQ---QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240

Query: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVG-AQLKSSINDAAEFR 248
           RV  Q P ER++H FY +L G S +  + L L  + S Y+Y+ +G       +NDA ++ 
Sbjct: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYA 299

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV----DGDTPLIENGKVVSIIAELL 304
            +  AMK++ F   E   V K+LAAILHLGN+ F+     + D   +        + +LL
Sbjct: 300 HIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLL 359

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
             +   +   L+  T+    + + +     +A+  RDAF K IY  LF WIV +IN  I 
Sbjct: 360 EVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIF 419

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
                   + +   IG+LDI+GFE F+NNSFEQ CIN+ NE LQQ F+Q V   EQEEY+
Sbjct: 420 TPPAQDPKNVRR-AIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478

Query: 425 REGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAH 484
            E I W +I Y +N+  +DL+  +   II++LD+      + TD   L+ LNS      H
Sbjct: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEE-SRFPQGTDLTMLQKLNS-----VH 532

Query: 485 FSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544
            +++       I   D  F I H+AG+V Y   GF++KN+D L  D   L+Y+S N  L+
Sbjct: 533 ANNKAFLQPKNI--HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590

Query: 545 NMW----PEGKL---------------SITEVTKRPLTAATLFKNSMIALVDNLASKEPY 585
            ++     E KL                  +  KRP T  + FK S+  L+  L + +PY
Sbjct: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650

Query: 586 YVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEF 645
           ++RCIKPN+ K P +FD E C  Q+ Y G++E V +R++GF  R T+E+F  R+ ++   
Sbjct: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVL--- 707

Query: 646 TWPNHDLPSDKEAVKKLIERCGFQD-------DVAYGKTKIFIRTPRTLFTLEELRAQML 698
             PN      +  ++++    G  D       D   GKTKIF+R  +    LE  R+Q+L
Sbjct: 708 -LPNAMRMQLQGKLRQM--TLGITDVWLRTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVL 763

Query: 699 IRIVLFLQKVWRGTLARMRY-KRTKAALTIIRYYRRY 734
            R  L +QKV RG   R  + ++ +AA+T+  ++R Y
Sbjct: 764 DRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGY 800


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  450 bits (1157), Expect = e-126
 Identities = 281/799 (35%), Positives = 430/799 (53%), Gaps = 55/799 (6%)

Query: 10  GKADFVLMDTVSMPEFMANLRLRF-EKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68
           G+ D   +  +  P  + NL++RF E   IYT+ G V+V++NPY+ L IYG+D I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129

Query: 69  RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128
           + + +  PH+FA+A+ AYK M R  K+  I++SGESGAGKT ++KY M+Y A +   +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE 189

Query: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
             +E     +L S+ ++EA GNAKT RNDNSSRFGKY+ I FD +   IG ++  YLLEK
Sbjct: 190 TNIEE---KVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248
           SRV+ Q   ER++H FYQL         + L L  +   +     G      ++DA +F 
Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFE 306

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV--DGDTPLIENGKV-VSIIAELLS 305
               A  ++G K     +++KI+A+ILHLG++      DGD+  I    V +S    LL 
Sbjct: 307 KTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLG 366

Query: 306 TKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365
            +   +E  L +R + T  +   K  + Q+    R+A AK IY +LF WIV  IN  +  
Sbjct: 367 VEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH- 425

Query: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425
                T   +++ IGVLDIYGFE F+ NSFEQFCINY NEKLQQ F   V K EQEEY +
Sbjct: 426 -----TSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480

Query: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485
           E IPW  ID+++NQ  +DL+E +  GI+ +LD+ C  V K TD+ + + L  +     HF
Sbjct: 481 EQIPWTLIDFYDNQPCIDLIEAK-LGILDLLDEEC-KVPKGTDQNWAQKLYDRHSSSQHF 538

Query: 486 SSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKN 545
              ++         +  F I H+A  V Y   GF++KN+DT++++   ++  S  P++ +
Sbjct: 539 QKPRMS--------NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVAD 590

Query: 546 MWPE----------GKLSITEVTKRPL-------------TAATLFKNSMIALVDNLASK 582
           ++ +          GK S ++++ R               T    F+ S+  L++ L + 
Sbjct: 591 LFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNAT 650

Query: 583 EPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI 642
            P+YVRCIKPND+K P  FD +R   Q+   G+LE +R+  AG+  R  Y  F +RY+++
Sbjct: 651 TPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL 710

Query: 643 SEFTWPNHDLPSDKEAV-KKLIER-CGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIR 700
            +         +DK+A+ + ++E      D   +G+TKIF R  +  + LE+LRA     
Sbjct: 711 VK---KRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAY-LEKLRADKFRT 766

Query: 701 IVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHV 760
             + +QK  RG L +++Y R K A   ++ Y R  +   + E  RR      ++   KH 
Sbjct: 767 ATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQ---KHY 823

Query: 761 KWPSPPKVLRRFEEALQTI 779
           +     +  +R   A   I
Sbjct: 824 RMQRARQAYQRVRRAAVVI 842


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
           sapiens]
          Length = 1935

 Score =  439 bits (1130), Expect = e-123
 Identities = 302/881 (34%), Positives = 461/881 (52%), Gaps = 62/881 (7%)

Query: 3   EQESLEFGKA-DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRD 61
           +Q   +F K  D  ++  +  P  + NL+ R+    IYT+ G   V+VNPYK L +Y  +
Sbjct: 78  QQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPE 137

Query: 62  TIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAA 121
            +  Y+G++  E PPH+F+I+D AY+ M    ++  I+I+GESGAGKT  +K ++QY A 
Sbjct: 138 VVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAV 197

Query: 122 ITNPSQRAEVER------VKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGD 175
           I     R++ ++      +++ ++++N  LEAFGNAKT RNDNSSRFGK++ I+F   G 
Sbjct: 198 IAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 257

Query: 176 PIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGA 235
                I  YLLEKSRVI Q   ER +H FYQ+L     ++L  L +  +   Y +I  G 
Sbjct: 258 LASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGE 317

Query: 236 QLKSSINDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--N 293
              +SI+DA E     +A  V+GF  EE  ++YK+  AI+H GN+KF +       E   
Sbjct: 318 TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDG 377

Query: 294 GKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFC 353
            +     A L+   +  + K L +  V  G + + K    Q+  Y   A AKA+YER+F 
Sbjct: 378 TEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFN 437

Query: 354 WIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQ 413
           W+VTRIN  +E K        +   IGVLDI GFEIFD NSFEQ CIN+ NEKLQQ F  
Sbjct: 438 WMVTRINATLETK------QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNH 491

Query: 414 LVLKQEQEEYQREGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFL 472
            +   EQEEY++EGI W  ID+  + Q  +DL+E+   GI++IL++ CM   K TD  F 
Sbjct: 492 HMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKP-MGIMSILEEECM-FPKATDMTFK 549

Query: 473 EAL-NSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDF 531
             L ++ LGK A+F   +          +  F + HYAG V Y++IG++ KNKD L +  
Sbjct: 550 AKLFDNHLGKSANFQKPRNIKGKP----EAHFSLIHYAGIVDYNIIGWLQKNKDPLNETV 605

Query: 532 KRLMYNSSNPVLKNMWPEGKLSITEVTKRP---------LTAATLFKNSMIALVDNLASK 582
             L   SS  +L  ++     +   + K            T + L + ++  L+ NL S 
Sbjct: 606 VGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRST 665

Query: 583 EPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMI 642
            P++VRCI PN+ KSP + D+    HQ+   G+LE +R+ R GF  R  Y  F  RY+++
Sbjct: 666 HPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL 725

Query: 643 SEFTWPNHDLPSDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRI 701
           +    P       ++  +KL+       +   +G TK+F +    L  LEE+R + L RI
Sbjct: 726 NPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSRI 784

Query: 702 VLFLQKVWRGTLARMRYKR---TKAALTIIRYYRRYKVKSYIHEVARRFHGVKT---MRD 755
           +  +Q   RG LARM YK+    + +L +I++              R F GVK    M+ 
Sbjct: 785 ITRIQAQSRGVLARMEYKKLLERRDSLLVIQWN------------IRAFMGVKNWPWMKL 832

Query: 756 YGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRA 815
           Y K +K      +L+  E   +    +   ++L +++  S+  +   +   V +L+ ++ 
Sbjct: 833 YFK-IK-----PLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ-EKN 885

Query: 816 DLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMN 856
           DL LQ   E + LA   D  +     +    +L+ K K MN
Sbjct: 886 DLQLQVQAEQDNLA---DAEERCDQLIKNKIQLEAKVKEMN 923


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  439 bits (1128), Expect = e-123
 Identities = 270/748 (36%), Positives = 412/748 (55%), Gaps = 42/748 (5%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D   +  ++    + NL+ R+  G IYT+ G   V +NPYK L IY  + IE Y+G++ +
Sbjct: 89  DMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRH 148

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132
           E PPH++AI+++AY+ M +  +D  I+ +GESGAGKTE +K ++QY+A + +  +  +  
Sbjct: 149 EMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDH 208

Query: 133 RV----KNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
            +    +  LL++N +LE+FGNAKT +NDNSSRFGK++ INFD  G  +G +I  YLLEK
Sbjct: 209 NIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248
           SR + Q   ER+FH FYQLL G  E  L+S  L +  ++Y ++  G        D   F+
Sbjct: 269 SRAVRQAKDERTFHIFYQLLSGAGEH-LKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQ 327

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306
              +AM ++GF  EEI ++ K+++++L  GN+ F  + +T    +    V   +  LL  
Sbjct: 328 ETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGM 387

Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366
                 +A+L   +  GRD + K  T+++A +  +A AKA YERLF W+V RIN     K
Sbjct: 388 NVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRIN-----K 442

Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426
             D T     + IG+LDI GFEIF+ NSFEQ CINY NEKLQQLF   +   EQEEYQRE
Sbjct: 443 ALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502

Query: 427 GIPWKHIDY-FNNQIIVDLVEQ--QHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483
           GI W  ID+  + Q  +DL+E+     G++A+LD+ C    K TD+ F+E L  + G H+
Sbjct: 503 GIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW-FPKATDKTFVEKLVQEQGSHS 561

Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543
            F         + L+   DF I HYAG V Y    ++ KN D L  +   L++ SS+  +
Sbjct: 562 KFQ------KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFV 615

Query: 544 KNMWPE-----GKLSITEVTKRPL------------TAATLFKNSMIALVDNLASKEPYY 586
             +W +     G   +T +T+               T   L+K S+  L+  L +  P +
Sbjct: 616 AELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNF 675

Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646
           VRCI PN +K     D      Q+   G+LE +R+ R GF  R  +++F  RY++++   
Sbjct: 676 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA 735

Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705
            P       K+A +++I       ++   G++KIF R    L  LEE R   +  I++F 
Sbjct: 736 IPK-GFMDGKQACERMIRALELDPNLYRIGQSKIFFRA-GVLAHLEEERDLKITDIIIFF 793

Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733
           Q V RG LAR  + + +  L+ ++  +R
Sbjct: 794 QAVCRGYLARKAFAKKQQQLSALKVLQR 821


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta
           [Homo sapiens]
          Length = 1983

 Score =  439 bits (1128), Expect = e-123
 Identities = 267/735 (36%), Positives = 402/735 (54%), Gaps = 39/735 (5%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D  +M  ++    + NLR R+ +  IYT+ G   V++NPYK L +Y    +  YKG+   
Sbjct: 130 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAIT----NPSQR 128
           + PPH++A+AD AY  M R   +  ++I+GESGAGKT  +K ++QY A +      P ++
Sbjct: 190 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249

Query: 129 AEVERVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHIN 182
           A+    K      + ++++N  +EAFGNAKT RNDNSSRFGK++ I+F   G      I+
Sbjct: 250 AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309

Query: 183 NYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSIN 242
           +YLLEKSRVI Q PGERS+H +YQ+L G   ++   L L  +   Y++   G     ++N
Sbjct: 310 SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITVDNMN 369

Query: 243 DAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSI--I 300
           D  E      AM ++GF  +E    YKI+ A+LH GN+KF         E     S    
Sbjct: 370 DGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKA 429

Query: 301 AELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIN 360
           A L+   +  + K LL+  V  G + + K  + ++  +   A AKA Y+RLF W+V+RIN
Sbjct: 430 AYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRIN 489

Query: 361 DIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQ 420
             ++ K        +   IGVLDI GFEIF+ NSFEQ CIN+ NEKLQQ F Q +   EQ
Sbjct: 490 QTLDTK------LPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQ 543

Query: 421 EEYQREGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSK 478
           EEY+REGI W  ID+  + Q  +DL+E+   GI++IL++ CM   K +D  F   L ++ 
Sbjct: 544 EEYKREGIDWVFIDFGLDLQPCIDLIEKP-LGILSILEEECM-FPKASDASFRAKLYDNH 601

Query: 479 LGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNS 538
            GK  +F   +    DK  ++   F + HYAG V YS++G+++KNKD L +    +   S
Sbjct: 602 AGKSPNFQQPR---PDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKS 658

Query: 539 SNPVLKNMWPE---------GKLSITEVTKRPL---TAATLFKNSMIALVDNLASKEPYY 586
            N +L  ++            K  + E  K+     T + L K ++  L+ NL + +P++
Sbjct: 659 QNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718

Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646
           VRCI PN+ K+P + D     HQ+   G+LE +R+ R GF  R  Y  F  RY++++   
Sbjct: 719 VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778

Query: 647 WPNHDLPSDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705
            P+      ++A +KL+           +G TK+F +    L  LEELR Q L +++  L
Sbjct: 779 IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKA-GLLGVLEELRDQRLAKVLTLL 837

Query: 706 QKVWRGTLARMRYKR 720
           Q   RG L R+ Y+R
Sbjct: 838 QARSRGRLMRLEYQR 852


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score =  435 bits (1119), Expect = e-122
 Identities = 267/748 (35%), Positives = 413/748 (55%), Gaps = 42/748 (5%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D   +  ++    + NLR R+  G IYT+ G   V VNPYK L IY    ++ YKG++ +
Sbjct: 89  DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130
           E PPH++AIAD AY++M +  +D  I+ +GESGAGKTE +K ++QY+A + +  +  +  
Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208

Query: 131 --VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
                ++  LL++N +LEAFGNAKT +NDNSSRFGK++ INFD  G  +G +I  YLLEK
Sbjct: 209 SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248
           SR I Q   ER+FH FY ++ G  E+M RS  L +  ++Y ++  G     +  D   F+
Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQ 327

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306
              +AM ++GF  EE  ++ K+++++L LGN+ F  + +T    + +      +  L+  
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387

Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366
                 +++L   +  GRD++ K  T+++A +  +A AKA YERLF WI+TR+N     K
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN-----K 442

Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426
             D T     + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF   +   EQEEYQRE
Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502

Query: 427 GIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483
           GI W  ID+  + Q  ++L+E+ +   G++A+LD+ C    K TD+ F+E L ++ G H 
Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLCTEQGSHP 561

Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543
            F         K L+   +F I HYAG V Y+   ++ KN D L  +   L+  SS+  +
Sbjct: 562 KFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615

Query: 544 KNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNLASKEPYY 586
            ++W                E  L     TK+ +  T   L+K  +  L+  L +  P +
Sbjct: 616 ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675

Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646
           VRCI PN +K     D      Q+   G+LE +R+ R GF  R  +++F  RY++++   
Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735

Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705
            P       K+A   +I+      ++   G++KIF RT   L  LEE R   +  +++  
Sbjct: 736 IPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMAF 793

Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733
           Q + RG LAR  + + +  LT ++  +R
Sbjct: 794 QAMCRGYLARKAFAKRQQQLTAMKVIQR 821


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score =  435 bits (1119), Expect = e-122
 Identities = 267/748 (35%), Positives = 413/748 (55%), Gaps = 42/748 (5%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D   +  ++    + NLR R+  G IYT+ G   V VNPYK L IY    ++ YKG++ +
Sbjct: 89  DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130
           E PPH++AIAD AY++M +  +D  I+ +GESGAGKTE +K ++QY+A + +  +  +  
Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208

Query: 131 --VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188
                ++  LL++N +LEAFGNAKT +NDNSSRFGK++ INFD  G  +G +I  YLLEK
Sbjct: 209 SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268

Query: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFR 248
           SR I Q   ER+FH FY ++ G  E+M RS  L +  ++Y ++  G     +  D   F+
Sbjct: 269 SRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQ 327

Query: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSIIAELLST 306
              +AM ++GF  EE  ++ K+++++L LGN+ F  + +T    + +      +  L+  
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387

Query: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366
                 +++L   +  GRD++ K  T+++A +  +A AKA YERLF WI+TR+N     K
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN-----K 442

Query: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426
             D T     + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF   +   EQEEYQRE
Sbjct: 443 ALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQRE 502

Query: 427 GIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALNSKLGKHA 483
           GI W  ID+  + Q  ++L+E+ +   G++A+LD+ C    K TD+ F+E L ++ G H 
Sbjct: 503 GIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLCTEQGSHP 561

Query: 484 HFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVL 543
            F         K L+   +F I HYAG V Y+   ++ KN D L  +   L+  SS+  +
Sbjct: 562 KFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615

Query: 544 KNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNLASKEPYY 586
            ++W                E  L     TK+ +  T   L+K  +  L+  L +  P +
Sbjct: 616 ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675

Query: 587 VRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFT 646
           VRCI PN +K     D      Q+   G+LE +R+ R GF  R  +++F  RY++++   
Sbjct: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735

Query: 647 WPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFL 705
            P       K+A   +I+      ++   G++KIF RT   L  LEE R   +  +++  
Sbjct: 736 IPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIMAF 793

Query: 706 QKVWRGTLARMRYKRTKAALTIIRYYRR 733
           Q + RG LAR  + + +  LT ++  +R
Sbjct: 794 QAMCRGYLARKAFAKRQQQLTAMKVIQR 821


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
           sapiens]
          Length = 1940

 Score =  432 bits (1111), Expect = e-121
 Identities = 265/749 (35%), Positives = 408/749 (54%), Gaps = 34/749 (4%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D  ++  ++ P  + NL+ R+    IYT+ G   V+VNPYK L +Y  + +E Y+G++  
Sbjct: 90  DMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQ 149

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132
           E PPH+F+I+D AY+ M    ++  I+I+GESGAGKT  +K ++QY A I      A+ +
Sbjct: 150 EAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK 209

Query: 133 RVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLL 186
             K      + ++ +N +LEAFGNAKT RNDNSSRFGK++ I+F   G      I  YLL
Sbjct: 210 DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLL 269

Query: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAE 246
           EKSRV  Q   ERS+H FYQ+L     +++  L +  +   Y +I  G  L +SI+DA E
Sbjct: 270 EKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDAEE 329

Query: 247 FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--NGKVVSIIAELL 304
                 A+ ++GF PEE   +YK+  A++H GN+KF         E    +V    A L+
Sbjct: 330 LLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLM 389

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
              +  + KAL +  V  G + + K  T  +  +  +A +K++YE+LF W+VTRIN  ++
Sbjct: 390 GLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD 449

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
            K        +   IGVLDI GFEIF+ NS EQ CIN+ NEKLQQ F   +   EQEEY+
Sbjct: 450 TK------LPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503

Query: 425 REGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKH 482
           +EGI W  ID+  +    ++L+E+   GI +IL++ CM   K TD  F   L +  LGK 
Sbjct: 504 KEGIEWTFIDFGMDLAACIELIEKP-MGIFSILEEECM-FPKATDTSFKNKLYDQHLGKS 561

Query: 483 AHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPV 542
            +F   K+         +  F + HYAG V YSV G+++KNKD L +    L   SSN +
Sbjct: 562 NNFQKPKVVKG----RAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRL 617

Query: 543 LKNMWPEGKLSITEVTKRPL---------TAATLFKNSMIALVDNLASKEPYYVRCIKPN 593
           L +++     +  +  K+ +         T + LF+ ++  L+ NL +  P++VRCI PN
Sbjct: 618 LAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPN 677

Query: 594 DKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLP 653
           + K+P   +     HQ+   G+LE +R+ R GF  R  Y  F  RY++++    P     
Sbjct: 678 ETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFI 737

Query: 654 SDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGT 712
             K+A +KL+           +G TK+F +    L TLEE+R   L +++   Q V RG 
Sbjct: 738 DSKKACEKLLASIDIDHTQYKFGHTKVFFKA-GLLGTLEEMRDDRLAKLITRTQAVCRGF 796

Query: 713 LARMRYKRTKAALTIIRYYRRYKVKSYIH 741
           L R+ +++       I +  +Y ++S+++
Sbjct: 797 LMRVEFQKMVQRRESI-FCIQYNIRSFMN 824


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score =  432 bits (1111), Expect = e-121
 Identities = 267/755 (35%), Positives = 413/755 (54%), Gaps = 49/755 (6%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D   +  ++    + NLR R+  G IYT+ G   V VNPYK L IY    ++ YKG++ +
Sbjct: 89  DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130
           E PPH++AIAD AY++M +  +D  I+ +GESGAGKTE +K ++QY+A + +  +  +  
Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208

Query: 131 ---------VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI 181
                       ++  LL++N +LEAFGNAKT +NDNSSRFGK++ INFD  G  +G +I
Sbjct: 209 SITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 268

Query: 182 NNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSI 241
             YLLEKSR I Q   ER+FH FY ++ G  E+M RS  L +  ++Y ++  G     + 
Sbjct: 269 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAA 327

Query: 242 NDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSI 299
            D   F+   +AM ++GF  EE  ++ K+++++L LGN+ F  + +T    + +      
Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387

Query: 300 IAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRI 359
           +  L+        +++L   +  GRD++ K  T+++A +  +A AKA YERLF WI+TR+
Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447

Query: 360 NDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQE 419
           N     K  D T     + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF   +   E
Sbjct: 448 N-----KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502

Query: 420 QEEYQREGIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALN 476
           QEEYQREGI W  ID+  + Q  ++L+E+ +   G++A+LD+ C    K TD+ F+E L 
Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLC 561

Query: 477 SKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMY 536
           ++ G H  F         K L+   +F I HYAG V Y+   ++ KN D L  +   L+ 
Sbjct: 562 TEQGSHPKFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 615

Query: 537 NSSNPVLKNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNL 579
            SS+  + ++W                E  L     TK+ +  T   L+K  +  L+  L
Sbjct: 616 ASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTL 675

Query: 580 ASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY 639
            +  P +VRCI PN +K     D      Q+   G+LE +R+ R GF  R  +++F  RY
Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735

Query: 640 KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQML 698
           ++++    P       K+A   +I+      ++   G++KIF RT   L  LEE R   +
Sbjct: 736 EILAANAIPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKI 793

Query: 699 IRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733
             +++  Q + RG LAR  + + +  LT ++  +R
Sbjct: 794 TDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQR 828


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score =  432 bits (1111), Expect = e-121
 Identities = 267/755 (35%), Positives = 413/755 (54%), Gaps = 49/755 (6%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D   +  ++    + NLR R+  G IYT+ G   V VNPYK L IY    ++ YKG++ +
Sbjct: 89  DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAE-- 130
           E PPH++AIAD AY++M +  +D  I+ +GESGAGKTE +K ++QY+A + +  +  +  
Sbjct: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT 208

Query: 131 ---------VERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI 181
                       ++  LL++N +LEAFGNAKT +NDNSSRFGK++ INFD  G  +G +I
Sbjct: 209 SITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 268

Query: 182 NNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSI 241
             YLLEKSR I Q   ER+FH FY ++ G  E+M RS  L +  ++Y ++  G     + 
Sbjct: 269 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKM-RSDLLLEGFNNYTFLSNGFVPIPAA 327

Query: 242 NDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDT--PLIENGKVVSI 299
            D   F+   +AM ++GF  EE  ++ K+++++L LGN+ F  + +T    + +      
Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387

Query: 300 IAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRI 359
           +  L+        +++L   +  GRD++ K  T+++A +  +A AKA YERLF WI+TR+
Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447

Query: 360 NDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQE 419
           N     K  D T     + +G+LDI GFEIF+ NSFEQ CINY NEKLQQLF   +   E
Sbjct: 448 N-----KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILE 502

Query: 420 QEEYQREGIPWKHIDY-FNNQIIVDLVEQQHK--GIIAILDDACMNVGKVTDEMFLEALN 476
           QEEYQREGI W  ID+  + Q  ++L+E+ +   G++A+LD+ C    K TD+ F+E L 
Sbjct: 503 QEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW-FPKATDKSFVEKLC 561

Query: 477 SKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMY 536
           ++ G H  F         K L+   +F I HYAG V Y+   ++ KN D L  +   L+ 
Sbjct: 562 TEQGSHPKFQ------KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLN 615

Query: 537 NSSNPVLKNMW---------------PEGKLSITEVTKRPL--TAATLFKNSMIALVDNL 579
            SS+  + ++W                E  L     TK+ +  T   L+K  +  L+  L
Sbjct: 616 ASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTL 675

Query: 580 ASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY 639
            +  P +VRCI PN +K     D      Q+   G+LE +R+ R GF  R  +++F  RY
Sbjct: 676 RNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRY 735

Query: 640 KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQML 698
           ++++    P       K+A   +I+      ++   G++KIF RT   L  LEE R   +
Sbjct: 736 EILAANAIPK-GFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKI 793

Query: 699 IRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRR 733
             +++  Q + RG LAR  + + +  LT ++  +R
Sbjct: 794 TDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQR 828


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
           [Homo sapiens]
          Length = 1937

 Score =  430 bits (1105), Expect = e-120
 Identities = 271/741 (36%), Positives = 398/741 (53%), Gaps = 36/741 (4%)

Query: 13  DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELY 72
           D  +M  +  P  + NL+ R+    IYT+ G   V+VNPYK L +Y  + +  Y+G++  
Sbjct: 92  DMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQ 151

Query: 73  ERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVE 132
           E PPH+F+I+D AY+ M    ++  I+I+GESGAGKT  +K ++QY A I    ++ + E
Sbjct: 152 EAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDE 211

Query: 133 RVK------NMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLL 186
             K      + ++ +N +LEAFGNAKT RNDNSSRFGK++ I+F   G      I  YLL
Sbjct: 212 SGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLL 271

Query: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAE 246
           EKSRV  Q   ERS+H FYQ+       ++  L +  +   Y ++  G     SI+D  E
Sbjct: 272 EKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEE 331

Query: 247 FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIE--NGKVVSIIAELL 304
                 A+ ++GF PEE  ++YK+  A++H GN+KF         E    +V    A L 
Sbjct: 332 LMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQ 391

Query: 305 STKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
           S  +  + KAL Y  V  G + + K  T Q+      A AKA+YE++F W+VTRIN  ++
Sbjct: 392 SLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD 451

Query: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
            K        +   IGVLDI GFEIFD NS EQ CIN+ NEKLQQ F   +   EQEEY+
Sbjct: 452 TK------QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505

Query: 425 REGIPWKHIDY-FNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEAL-NSKLGKH 482
           +EGI W  ID+  +    ++L+E+   GI +IL++ CM   K TD  F   L +  LGK 
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKP-LGIFSILEEECM-FPKATDTSFKNKLYDQHLGKS 563

Query: 483 AHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPV 542
           A+F   K+       + +  F + HYAG V Y++ G++DKNKD L      L   S+   
Sbjct: 564 ANFQKPKVVKG----KAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKT 619

Query: 543 LKNMW-----PEGKLSITEVTKRP----LTAATLFKNSMIALVDNLASKEPYYVRCIKPN 593
           L +++      E   S  +  K+      T + LF+ ++  L+ NL S  P++VRCI PN
Sbjct: 620 LASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 679

Query: 594 DKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLP 653
           + K+P   + E   HQ+   G+LE +R+ R GF  R  Y  F  RYK+++    P     
Sbjct: 680 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFI 739

Query: 654 SDKEAVKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGT 712
             K+A +KL+           +G TK+F +    L  LEE+R + L +I+   Q V RG 
Sbjct: 740 DSKKASEKLLASIDIDHTQYKFGHTKVFFKA-GLLGLLEEMRDEKLAQIITRTQAVCRGF 798

Query: 713 LARMRYKR---TKAALTIIRY 730
           L R+ Y++    + AL  I+Y
Sbjct: 799 LMRVEYQKMLQRREALFCIQY 819


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,895,468
Number of Sequences: 37866
Number of extensions: 1459012
Number of successful extensions: 3569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3098
Number of HSP's gapped (non-prelim): 124
length of query: 1006
length of database: 18,247,518
effective HSP length: 112
effective length of query: 894
effective length of database: 14,006,526
effective search space: 12521834244
effective search space used: 12521834244
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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