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Search of human proteins with 50428917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo
sapiens]
(410 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sap... 821 0.0
gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo sap... 603 e-173
gi|148746195 trichohyalin [Homo sapiens] 66 7e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 64 2e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 64 2e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 64 2e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 64 2e-10
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 62 1e-09
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 55 1e-07
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 55 1e-07
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 54 2e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 6e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 51 2e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 2e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 3e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 3e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 50 3e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 6e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 6e-06
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 49 1e-05
gi|81295809 pericentrin [Homo sapiens] 48 1e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 2e-05
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 48 2e-05
gi|157266264 pleckstrin homology-like domain, family B, member 3... 48 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 3e-05
gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 47 4e-05
gi|126362971 serine/threonine kinase 10 [Homo sapiens] 47 4e-05
>gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo
sapiens]
Length = 410
Score = 821 bits (2120), Expect = 0.0
Identities = 410/410 (100%), Positives = 410/410 (100%)
Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG
Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR
Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE
Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240
AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL
Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240
Query: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300
KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG
Sbjct: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300
Query: 301 LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT 360
LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT
Sbjct: 301 LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT 360
Query: 361 VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF 410
VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF
Sbjct: 361 VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF 410
>gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo
sapiens]
Length = 307
Score = 603 bits (1555), Expect = e-173
Identities = 306/317 (96%), Positives = 306/317 (96%), Gaps = 11/317 (3%)
Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG
Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR
Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE
Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240
AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST WARSWAYRDSL
Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST-----------WARSWAYRDSL 229
Query: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300
KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG
Sbjct: 230 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 289
Query: 301 LEQSGGCWNMNSGNSWG 317
LEQSGGCWNMNSGNSWG
Sbjct: 290 LEQSGGCWNMNSGNSWG 306
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/206 (26%), Positives = 103/206 (50%), Gaps = 10/206 (4%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL---QLMQSKYK 133
R E Q EQ+L ++ + + R K R +SE ++R++Q+ QL++ + +
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE 555
Query: 134 QKLKREE-SVRIKKEAEEA--ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKT 190
++L++E R+K+E EE +L K + +R++ K E+++RL++ L+RE +Q +
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 191 AEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQK 250
E +L E P+ Q + + + L R+ R R + EE R Q+
Sbjct: 616 RE--QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE--QRLKREEEEERLEQR 671
Query: 251 MKDEQHQKSELLELKRQQQEQERAKI 276
+K E ++ EL ++QEQ R +I
Sbjct: 672 LKREHEEERREQELAEEEQEQARERI 697
Score = 57.0 bits (136), Expect = 3e-08
Identities = 52/230 (22%), Positives = 103/230 (44%), Gaps = 15/230 (6%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R E Q + E E L + Q R + ++L + E + Q++Q QL + + ++K
Sbjct: 1670 REEEQLLQEGEEQQLRR---QERDRKFREEEQQLRRQERERKFLQEEQ-QLRRQELERKF 1725
Query: 137 KREESVRIKKEAEEAELQKM--KAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
+ EE +R + E E+ Q+ K ++ E+ E+++L+ R FRE +Q +
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254
+L ++ DR + + +L RD + W E+ ++L++ +D
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY--RWEEEQLQLEEQEQRLRQERDR 1843
Query: 255 QHQKSELL----ELKRQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQ 297
Q++ E + +R++QE +E K Q R++ + R Q + Q
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 56.2 bits (134), Expect = 5e-08
Identities = 65/266 (24%), Positives = 116/266 (43%), Gaps = 24/266 (9%)
Query: 25 QDPSGRQGELSPVEDQ---REGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81
Q G + E P E+Q RE LE KG E +R+ + R+ E
Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKG-REEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141
E+E E+ + Q + R+L + E ++++Q Q Q+L+RE+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-------QRLRREQQ 305
Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEK-----KRLQENLRREAFREHQQYKTAEFLSK 196
+R K+E E E Q+ + Q+E+ + EE+ +R QE R + R Q+ + E +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE--QQ 363
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256
L E + Q + + L R+ R R + ++ R+ Q+++ EQ
Sbjct: 364 LRREQEEERREQQ--LRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQLRREQQ 418
Query: 257 QKSELLELKRQQQEQERAKIHQTEHR 282
+ E +L+R+Q+E+ + H+ E R
Sbjct: 419 LRRE-QQLRREQEEERHEQKHEQERR 443
Score = 54.7 bits (130), Expect = 2e-07
Identities = 65/293 (22%), Positives = 123/293 (41%), Gaps = 37/293 (12%)
Query: 38 EDQREGLEAAPKGPSRESVVHAGQR--RTSAYTLIAPNINRRNEIQRIAEQELANLEKWK 95
E++RE E + RE QR R + + +++R E+ L K +
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 96 EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQK 155
E+ R + RR + E E R+ Q L+ + + +Q+LKRE+ R+++ + E+++
Sbjct: 554 EEKRLEQ----ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 156 M----KAIQREKSNKLEEKKRL-------QENLRREAFREHQQYKTAEFLSKLNTE---- 200
+ + QR K + EE++R QE R++ R QQ + + L + E
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 201 -----SPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR--------K 247
+ + + + + I R W W A +++ +
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKW--QWQLESEADARQSKVYSRPRKQE 727
Query: 248 LQKMKDEQHQKSELLELKRQQQEQERA-KIHQTEHRRVNNAFLDRLQGKSQPG 299
Q+ + EQ +K E + Q QE+ERA + Q E +R + + + + KS+ G
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Score = 54.3 bits (129), Expect = 2e-07
Identities = 58/267 (21%), Positives = 122/267 (45%), Gaps = 38/267 (14%)
Query: 26 DPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAE 85
+P RQ E P + +R+ K +E + G+ ++ + + + QR E
Sbjct: 123 EPRDRQLEEEPGQRRRQ------KRQEQERELAEGEEQSEKQERL-----EQRDRQRRDE 171
Query: 86 QELANLEKWKEQNRAKPVHLVPRRLGGSQSET-----EVRQKQQLQLMQS--KYKQKLKR 138
+ ++W+E+ + + G ++E ++R+++ L+L + + KQ+ +R
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
E R+ +E EE E +K + + R++ KL+E++ ++ RE E +Q + E +L
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ---RELQEEEEQLRKLE-RQELR 287
Query: 199 TESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK 258
E + Q L R+ R + EE R+ Q+ +++Q ++
Sbjct: 288 RERQEEEQQQQR-------------LRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 259 SELLELKRQQQE--QERAKIHQTEHRR 283
E +L+R+Q+E +++ + Q E RR
Sbjct: 335 REQ-QLRREQEERREQQLRREQEEERR 360
Score = 53.5 bits (127), Expect = 3e-07
Identities = 57/232 (24%), Positives = 108/232 (46%), Gaps = 35/232 (15%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQ 134
R +++R E+E + +EQ + L RR + E ++R++QQL+ Q + +Q
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
+L+RE+ +R ++E E E QK + +RE+ K E+++R R E H+Q + + L
Sbjct: 418 QLRREQQLRREQEEERHE-QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254
+ E R W + + + ++ R+ Q+++ E
Sbjct: 477 KRDQEEE------------------------RRERWLK--LEEEERREQQERREQQLRRE 510
Query: 255 QHQKSELLELKRQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQ 303
Q ++ E LKRQ++E Q+R + Q + RR ++L + + LEQ
Sbjct: 511 QEERRE-QRLKRQEEEERLQQRLRSEQ-QLRREQEERREQLLKREEEKRLEQ 560
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 47/215 (21%)
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120
+RR + Y A R E Q + E+E + +E+ R + + E + R
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ------------EQERQYR 931
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL---EEKKRLQENL 177
+++QLQ + +++L REE + +++ E + +K K +Q+++ L EK+R QE
Sbjct: 932 EEEQLQ----QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-- 985
Query: 178 RREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYR 237
R + +RE ++ + E +L E ++ R W R + +
Sbjct: 986 REKKYREEEELQQEE--EQLLREEREKR--------------------RRQEWERQYRKK 1023
Query: 238 DSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQE 272
D L+ EE + L+ E+ +K L E +RQ +E+E
Sbjct: 1024 DELQQEEEQLLR----EEREKRRLQERERQYREEE 1054
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/219 (25%), Positives = 97/219 (44%), Gaps = 30/219 (13%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
RR E R +E L + Q R + ++L + E + R+++QL+ Q +++
Sbjct: 1685 RRQERDRKFREEEQQLRR---QERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQ 1739
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLS 195
L+R+E R +K EE +L+ + Q+ + + + K R +E LR+E RE QQ ++ E
Sbjct: 1740 LRRQE--RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE--REEQQLRSQESDR 1795
Query: 196 KLNTESPDRSACQSAVCGPQSST----WKLPILPRDHSWARSWAYRD-SLKAEEN----- 245
K E R + PQ W+ L + R RD +AEE
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 246 -----------RKLQKMKDEQHQKSELLELKRQQQEQER 273
+ QK + E+ +K ++RQQ+E++R
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 48.5 bits (114), Expect = 1e-05
Identities = 52/225 (23%), Positives = 94/225 (41%), Gaps = 35/225 (15%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRL--GGSQSETEVRQKQQLQLMQSKYK 133
R+ E QR E LE+ Q R + R L G QSE + R +Q+ + + +
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEF 193
+ ++E R ++ AEE +LQ K + E+ E+ +R + R RE +Q + E
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL----- 248
++ E + + W R+++ +E KL
Sbjct: 234 QDRVFQEEEE----------------------------KEWRKRETVLRKEEEKLQEEEP 265
Query: 249 QKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293
Q+ ++ Q ++ +L +L+RQ+ +ER + Q + R L R Q
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
Score = 45.8 bits (107), Expect = 7e-05
Identities = 44/213 (20%), Positives = 91/213 (42%), Gaps = 34/213 (15%)
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLE-KWKEQNRAKPVHLVPRRLGGSQSETEV 119
Q R + + R+ ++ EQEL + E + K + +H R+ Q E ++
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 120 RQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR 179
R++++ Q + +K + EE +R +E E Q++ +R++ +LEE+K ++ R
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLR-----QEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 180 EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDS 239
+ + QQ + E +L E RD +
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQE-------------------------RDRKFRED---EQL 1627
Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQE 272
L+ E ++L + + ++ E +L+RQ++EQ+
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/222 (20%), Positives = 104/222 (46%), Gaps = 37/222 (16%)
Query: 76 RRNEIQRIAEQELAN-------LEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLM 128
+++E+Q+ EQ L E+ ++ + + +L G + ET RQ+ + Q
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 129 QSKYKQK----LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK--KRLQENLRREAF 182
+ + Q+ L REE + +++ E + ++ + +Q+E+ L E+ KR ++ L R+ +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ-Y 1140
Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKA 242
RE ++ + E +L E P++ R R + + L+
Sbjct: 1141 REEEEVQQEE--EQLLREEPEKR--------------------RRQELERQYREEEELQQ 1178
Query: 243 EENRKLQKMKDEQHQKSELLELKRQQ-QEQERAKIHQTEHRR 283
EE + L++ ++++ Q+ E + ++ Q Q+R + ++ E +R
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/236 (23%), Positives = 104/236 (44%), Gaps = 30/236 (12%)
Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANL-EKWKEQNRAKPVH----LVPRRLGGSQS 115
+R T + + E+Q+ EQ L EK + Q R + L +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSN-KLEEKKRLQ 174
E E R++Q+L+ Q + ++++++EE +++E E+ Q+++ RE+ + EE++ L+
Sbjct: 1127 EREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
E + +QY+ E L + + R Q S K P +
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDE-------DQRSDLKWQWEPEKEN----- 1233
Query: 235 AYRDS---LKAEENRKLQKMKDEQ----HQKSELLELKRQQQEQERAKIHQTEHRR 283
A RD+ K EN + ++++D Q + +L L +QQE++R + E RR
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR----EQERRR 1285
Score = 42.7 bits (99), Expect = 6e-04
Identities = 61/278 (21%), Positives = 120/278 (43%), Gaps = 41/278 (14%)
Query: 38 EDQREGL----EAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQR-----IAEQEL 88
EDQR L E + R++ V+ R + + + R + Q+ + EQ+
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 89 ANLE----KWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQ-LQLMQSKYKQKLKREESVR 143
+ E +W++++R P R +++ R+ Q+ QL++ + ++K +R+E+ R
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 144 IKKEAE----EAELQKMKAIQREKSNK-------------LEEKKRLQENLRREAF-REH 185
+E E E E Q ++ +R++ + LEE++RL+ R F +E
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 186 QQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEEN 245
QQ + E +L + + + Q K + R R L+ E
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK--FREEEQQVRRQERERKFLEEE-- 1452
Query: 246 RKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
Q+++ E+H+K E ++ QE+E ++H+ E R
Sbjct: 1453 ---QQLRQERHRK--FREEEQLLQEREEQQLHRQERDR 1485
Score = 42.4 bits (98), Expect = 8e-04
Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 34/215 (15%)
Query: 79 EIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK--- 135
++ R ++ E+ ++ + K + +L G + E RQ+++ + + + Q+
Sbjct: 942 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 136 -LKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---KKRLQENLRREAFREHQQYKTA 191
L REE + +++ E + +K +Q+E+ L E K+RLQE R +RE ++ +
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE--RERQYREEEELQQE 1059
Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKM 251
E + G + T R R + + L+ EE + L++
Sbjct: 1060 E----------------EQLLGEERET------RRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 252 KDE---QHQKSELLELKRQQQEQERAKIHQTEHRR 283
++ Q ++ + E + QQE+E+ + E RR
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/256 (19%), Positives = 104/256 (40%), Gaps = 49/256 (19%)
Query: 74 INRRNEIQRIAEQELANLEKWKE----------QNRAKPVHLVPRRLGGSQSETEVRQ-- 121
+ R+ ++ E+EL + E+ ++ Q R + ++L + E ++RQ
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 122 -----KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL-EEKKRLQE 175
+++ QL + + +K + EE ++E E L++ + +++E+ K EE++ LQE
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 176 NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWA 235
++ R+ + K E +L + DR + + +S + L + R
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL---RSQEPERKFLEEEQQLHRQQR 1529
Query: 236 YRDSLKAE----------------------------ENRKLQKMKDEQHQKSELLELKRQ 267
R L+ E E + Q + E+ +K L E K +
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 268 QQEQERAKIHQTEHRR 283
+QEQER + + R
Sbjct: 1590 RQEQERKFMEDEQQLR 1605
Score = 39.7 bits (91), Expect = 0.005
Identities = 56/259 (21%), Positives = 108/259 (41%), Gaps = 46/259 (17%)
Query: 36 PVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWK 95
P+ +QRE R+ Q+R + +R +R E+EL LE+ +
Sbjct: 789 PLREQRE----------RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 96 EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVR----IKKEAEEA 151
+ R + + G Q + E R+ Q+ Q K++ +L+ E R K A +
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL----SKLNTESPDRSAC 207
+L+K + + +E+ +L+ ++R E RR+ + +QY+ E L +L E ++
Sbjct: 898 QLRKEQQLLQEEEEELQREER--EKRRRQ--EQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 208 QSAVCGPQSSTWKLPILPRDHSWARSWAYR---DSLKAEENRKLQKMKDEQHQKSELLEL 264
Q R+ + + + + L EE K ++ + E+ + E
Sbjct: 954 QE----------------RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE---- 993
Query: 265 KRQQQEQERAKIHQTEHRR 283
+ QQE+E+ + E RR
Sbjct: 994 EELQQEEEQLLREEREKRR 1012
Score = 37.7 bits (86), Expect = 0.019
Identities = 39/172 (22%), Positives = 77/172 (44%), Gaps = 10/172 (5%)
Query: 31 QGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELAN 90
Q +L E R+ LE P RE Q R + + + E Q++ QE
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDR 1795
Query: 91 LEKWKEQNRAKPVHLVPRRLGGSQSETEVR-QKQQLQLMQSKYKQKLKREESVRIKK--- 146
+ +EQ R + ++L Q + + R +++QLQL + + + + +R+ R ++
Sbjct: 1796 KFREEEQLRQEREE---QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852
Query: 147 --EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196
E E Q++ + +K + E+K +E++RR+ E + + E S+
Sbjct: 1853 TQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 37.4 bits (85), Expect = 0.025
Identities = 51/265 (19%), Positives = 109/265 (41%), Gaps = 35/265 (13%)
Query: 30 RQGELSPVEDQREGLEAAPKGPSR--------ESVVHAGQRRTSAYTLIAPNINRRNEIQ 81
R+ EL E++R + + R E G++R SA P + + E Q
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA----RPPLREQRERQ 797
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141
AE+ +++ + K RR + E E++ ++ + +Q + + + +EE
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRR----EREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTES 201
++++ E Q+ + Q+ + EE+KR + L + + Q K + L + E
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-EEEE 912
Query: 202 PDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE---QHQK 258
R + R R + + L+ EE + L++ +++ Q ++
Sbjct: 913 LQREEREKR---------------RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 259 SELLELKRQQQEQERAKIHQTEHRR 283
+ + K+ QQ++E+ + E RR
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRR 982
Score = 36.2 bits (82), Expect = 0.055
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 32/220 (14%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK--- 133
R E Q++ QE +EQ + H R+ + + R++QQL + K
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERH---RKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 134 --QKLKREESVRIKKEAE-------------EAELQKM----KAIQREKSNKLEEKKRLQ 174
Q+L+R+E R +E E E +L + K +Q E+ + +E+ + +
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRS-ACQSAVCGPQSSTWKLPILPRDHSWARS 233
R FRE +Q + +L+ + DR + Q K D R
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK---FMEDEQQLRR 1606
Query: 234 WAYRDSLKAEENRKLQKMKDEQ-HQKSELLELKRQQQEQE 272
+ L+ E +RK + +DEQ Q+ E +L RQ+++++
Sbjct: 1607 QEGQQQLRQERDRKFR--EDEQLLQEREEQQLHRQERDRK 1644
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 788 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 839
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 899
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253
L +L + + Q + P SSTW + + + K EE R+ Q ++
Sbjct: 900 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 957
Query: 254 EQHQKSELLELKRQQQEQERAKI 276
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 958 QRRQQRELMKALQQQQQQQQQKL 980
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 835
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256
E + A + + +L + R + E R+ + M+ Q
Sbjct: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895
Query: 257 QKSELLELKRQQQEQERAKI 276
Q+ L L++QQQ+Q+ A++
Sbjct: 896 QQEALRRLQQQQQQQQLAQM 915
Score = 28.9 bits (63), Expect = 8.8
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152
A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++
Sbjct: 591 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 645
Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
Q+ A+ ++ L K R+ + N+ R T T S +V
Sbjct: 646 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 703
Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270
P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E
Sbjct: 704 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 761
Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293
R + + RR R Q
Sbjct: 762 ILRRQQEEERKRREEEELARRKQ 784
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 815 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 866
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 926
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253
L +L + + Q + P SSTW + + + K EE R+ Q ++
Sbjct: 927 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 984
Query: 254 EQHQKSELLELKRQQQEQERAKI 276
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 985 QRRQQRELMKALQQQQQQQQQKL 1007
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 862
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256
E + A + + +L + R + E R+ + M+ Q
Sbjct: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922
Query: 257 QKSELLELKRQQQEQERAKI 276
Q+ L L++QQQ+Q+ A++
Sbjct: 923 QQEALRRLQQQQQQQQLAQM 942
Score = 28.9 bits (63), Expect = 8.8
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152
A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++
Sbjct: 618 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 672
Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
Q+ A+ ++ L K R+ + N+ R T T S +V
Sbjct: 673 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 730
Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270
P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E
Sbjct: 731 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 788
Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293
R + + RR R Q
Sbjct: 789 ILRRQQEEERKRREEEELARRKQ 811
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253
L +L + + Q + P SSTW + + + K EE R+ Q ++
Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963
Query: 254 EQHQKSELLELKRQQQEQERAKI 276
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256
E + A + + +L + R + E R+ + M+ Q
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Query: 257 QKSELLELKRQQQEQERAKI 276
Q+ L L++QQQ+Q+ A++
Sbjct: 902 QQEALRRLQQQQQQQQLAQM 921
Score = 28.9 bits (63), Expect = 8.8
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152
A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++
Sbjct: 597 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 651
Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
Q+ A+ ++ L K R+ + N+ R T T S +V
Sbjct: 652 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 709
Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270
P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E
Sbjct: 710 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 767
Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293
R + + RR R Q
Sbjct: 768 ILRRQQEEERKRREEEELARRKQ 790
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E
Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845
Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193
E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253
L +L + + Q + P SSTW + + + K EE R+ Q ++
Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963
Query: 254 EQHQKSELLELKRQQQEQERAKI 276
++ Q+ EL++ +QQQ+Q++ K+
Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%)
Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196
E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256
E + A + + +L + R + E R+ + M+ Q
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901
Query: 257 QKSELLELKRQQQEQERAKI 276
Q+ L L++QQQ+Q+ A++
Sbjct: 902 QQEALRRLQQQQQQQQLAQM 921
Score = 28.9 bits (63), Expect = 8.8
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152
A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++
Sbjct: 597 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 651
Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
Q+ A+ ++ L K R+ + N+ R T T S +V
Sbjct: 652 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 709
Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270
P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E
Sbjct: 710 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 767
Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293
R + + RR R Q
Sbjct: 768 ILRRQQEEERKRREEEELARRKQ 790
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/239 (25%), Positives = 95/239 (39%), Gaps = 27/239 (11%)
Query: 10 SGLGASPASRPTRDPQDPSGRQGELSPVEDQREGL----EAAPKGPSRESVVHAGQRRTS 65
S ASPA P P P+ Q E P E + AP P S AG
Sbjct: 539 SAAPASPAPSPAPSPT-PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDRE 597
Query: 66 AYTLIAPNINRRNEIQRIAEQELANLE-----KWKEQNRAKPVHLVPRRLGGSQ--SETE 118
T + R+ QR E++ L+ + +E+ A+ R ++ E E
Sbjct: 598 EATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQE 657
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
R+K Q + + + QK K E R ++EAE L++ K Q+++ + E +KRL+E ++
Sbjct: 658 AREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMK 717
Query: 179 REAFREHQQYKTAEFLSKLNT--ESPD-------------RSACQSAVCGPQSSTWKLP 222
R E + K + + N SP+ + A Q PQ W LP
Sbjct: 718 RTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLP 776
Score = 36.6 bits (83), Expect = 0.042
Identities = 37/173 (21%), Positives = 79/173 (45%), Gaps = 18/173 (10%)
Query: 23 DPQDPSGRQGEL-SPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNI------- 74
+P+ PSG+ G +P +++ EA +GP+ ++ R + +P
Sbjct: 67 EPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126
Query: 75 NRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134
+ E+++ E+ L K + + RAK +L ++ + E + + ++ QL + +
Sbjct: 127 PTKQEVKKAGERH--KLAKERREERAK--YLAAKKAVWLEKEEKAKALREKQLQERR--- 179
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
+R E R+K E A L++ + + EK NK + +Q ++++ QQ
Sbjct: 180 --RRLEEQRLKAEQRRAALEERQRQKLEK-NKERYEAAIQRSVKKTWAEIRQQ 229
Score = 35.4 bits (80), Expect = 0.094
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 14/159 (8%)
Query: 161 REKSNKLEEKKRLQENLRREAFREHQQYKT-AEFLSKLNTESPDRSACQSAVCGPQSSTW 219
RE++ +L +KR Q +RE RE Q+ + AE ++ E R A A ++
Sbjct: 596 REEATRLLAEKRRQAREQRE--REEQERRLQAERDKRMREEQLAREAEARAEREAEARR- 652
Query: 220 KLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQT 279
R+ AR A + EE +LQK K+E +S E +RQ+ E+E+ Q
Sbjct: 653 ------REEQEAREKAQAEQ---EEQERLQKQKEEAEARSRE-EAERQRLEREKHFQQQE 702
Query: 280 EHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWGS 318
+ R+ L+ + +++ + ++ + N+ GS
Sbjct: 703 QERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGS 741
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 55.1 bits (131), Expect = 1e-07
Identities = 60/215 (27%), Positives = 95/215 (44%), Gaps = 26/215 (12%)
Query: 79 EIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEV----RQKQQLQLMQSKY 132
E +R+ EQ L LE+ W+E R + L+ G + E R++QQ L +
Sbjct: 244 EKRRLEEQRLQALERRLWEENRRQE---LLEEEGEGQEPPLEAERAPREEQQRSLEAPGW 300
Query: 133 KQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
+ +RE R + EAEE + Q E+ +LEE RL+E R +E ++ + AE
Sbjct: 301 EDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRR----QEEEEGRCAE 356
Query: 193 FLSKLNTES----PDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL 248
L + E + ++ V GP P + R A + L EE
Sbjct: 357 ELKRQEEEEAEGWEELEQQEAEVQGP-------PEALEETGEGRRGAEEEDLGEEEEEGQ 409
Query: 249 QKMKDEQHQKSELL-ELKRQQQEQERAKIH-QTEH 281
++D + Q SELL + + + ++QER K Q EH
Sbjct: 410 AHLEDWRGQLSELLNDFEERLEDQERLKPEGQREH 444
Score = 37.7 bits (86), Expect = 0.019
Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 28/189 (14%)
Query: 11 GLGASPASRPTRDPQDPSGRQGELSPVED-------QREGLEAAPKGPSRESVVHAGQRR 63
G G P R P++ R E ED +RE LEA + ++ A +RR
Sbjct: 274 GEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERR 333
Query: 64 TSAYTLIAPNINRRNE-----IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETE 118
R+ E + + QE E W+E Q E E
Sbjct: 334 RLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELE---------------QQEAE 378
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
V+ + L ++ ++ EE + ++E +A L+ + E N EE+ QE L+
Sbjct: 379 VQGPPEA-LEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLK 437
Query: 179 REAFREHQQ 187
E REH +
Sbjct: 438 PEGQREHSE 446
Score = 34.3 bits (77), Expect = 0.21
Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 41/201 (20%)
Query: 17 ASRPTRDPQDPSGRQGELSPVEDQREGLEAAP---KGPSRESVVHAGQRRTSAYTLIAPN 73
A RP +P +PS E S D+R P KG R+ A +R+ ++ L A
Sbjct: 993 AGRPDPEPSEPSKEDQESS---DRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQ 1049
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ ++ +E KP+ L GS+ +V Q L + + K
Sbjct: 1050 QEKPSQTPEAGRKE-------------KPMLQSRHSLDGSKLTEKVETAQPLWITLALQK 1096
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQRE--------------------KSNKLEEKKRL 173
QK RE+ ++ + E ++ + + +E KS L E+KR
Sbjct: 1097 QKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRP 1156
Query: 174 QENLRREAFREHQQYKTAEFL 194
+ + R RE Q K A L
Sbjct: 1157 ETAVSRLERRE--QLKKANTL 1175
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 7/118 (5%)
Query: 76 RRNEI-QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134
+R E+ QR+AE+ E+ + A+ +L E +R++++ + Q +
Sbjct: 511 KREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQ--- 567
Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192
+EE R+++EAE ++ K QRE+ +LE KKRL+E ++R E KT++
Sbjct: 568 ---KEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSD 622
Score = 33.1 bits (74), Expect = 0.47
Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 22/145 (15%)
Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198
EE+ R+ L + + + RE+ K E ++R QE L R+ E Q E ++
Sbjct: 477 EEATRL--------LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRRE 528
Query: 199 TESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK 258
ES A Q+ ++ R R + EE + Q+ K+E+ +
Sbjct: 529 EESRRLEAEQAR--------------EKEEQLQRQAEERALREREEAERAQRQKEEEARV 574
Query: 259 SELLELKRQQQEQERAKIHQTEHRR 283
E E RQ++E+ + Q R
Sbjct: 575 REEAERVRQEREKHFQREEQERLER 599
Score = 32.7 bits (73), Expect = 0.61
Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 25/180 (13%)
Query: 127 LMQSKYKQKLKREESVRIKKEAEEAELQKMKAI-----QREKSNKLEEKKRLQENLRREA 181
L + + + +RE+ R ++E EE E QK + + + + + EE +RL+ RE
Sbjct: 483 LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQARE- 541
Query: 182 FREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLK 241
+E Q + AE + E +R+ Q AR + ++
Sbjct: 542 -KEEQLQRQAEERALREREEAERAQRQK------------------EEEARVREEAERVR 582
Query: 242 AEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGL 301
E + Q+ + E+ ++ + LE ++ + A +T +R + L G ++ L
Sbjct: 583 QEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSAL 642
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/176 (22%), Positives = 92/176 (52%), Gaps = 5/176 (2%)
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
++Q+LQ ++ + +++ +RE+ ++ AEE + ++++ ++RE+ K EEK R +E +R+
Sbjct: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER--KREEKLRKREQKQRD 331
Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQS-AVCGPQSSTWKLPILPRDHSWARSWAYRDS 239
Q K + ++ + ++ + + Q + + ++ S A++ R+
Sbjct: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391
Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295
+ EE +LQ + E+ ++ + EL+R ++E+ERA Q + R + L L K
Sbjct: 392 EQKEEKLRLQ--QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSK 445
Score = 40.0 bits (92), Expect = 0.004
Identities = 46/206 (22%), Positives = 98/206 (47%), Gaps = 38/206 (18%)
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIK------KEAEEAELQKMKAIQREKSNKLEEKKR 172
++ L+ M+ YK + + + IK K +A ++K + ++R+K +LE+++
Sbjct: 228 IQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKK-RQLERQKLQELEQQR- 285
Query: 173 LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR 232
+E RRE +E ++ + AE + E +R + + K RD R
Sbjct: 286 -EEQKRRE--KEAEERQRAEERKQKELEELERERKR------EEKLRKREQKQRDRELRR 336
Query: 233 SWAYRDSLKAEENRKLQ-KMKDEQHQ-------------------KSELLELKRQQQEQE 272
+ + L+AEE ++LQ K+K E+ + +++ ++L+ Q+Q++E
Sbjct: 337 NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEE 396
Query: 273 RAKI-HQTEHRRVNNAFLDRLQGKSQ 297
+ ++ Q E RR+ A L R++ + +
Sbjct: 397 KLRLQQQEERRRLQEAELRRVEEEKE 422
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 52.8 bits (125), Expect = 6e-07
Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 23/208 (11%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
++I EQE EK +EQ RR E E + ++Q ++M K ++K++R+E
Sbjct: 321 EKIREQE----EKIREQEEKM------RRQEEMMWEKEEKMRRQEEMMWEK-EEKMRRQE 369
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQYKTAEFL 194
+ +KE + ++M + EK +LEEK R QE R+E + +Q K E
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254
+K+ + + + + W+ ++ R+ K +E ++ + +++
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 255 QHQKSELLELKRQQQEQERAKIHQTEHR 282
H++ E+ K + EQE KI + E +
Sbjct: 485 IHEQEEIWRQKEKMHEQEE-KIRKQEEK 511
Score = 52.0 bits (123), Expect = 1e-06
Identities = 54/260 (20%), Positives = 107/260 (41%), Gaps = 21/260 (8%)
Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
+ +Q + E K E + +R+ + R + ++I EQE + W++
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 456
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQK 155
+ + + + E RQ++++ + ++QK K E+ +I+K+ E+ Q+
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 156 MKAI--------QREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSAC 207
K Q EK + EEK R QE + RE + H+Q K E + E D+
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEKRQEQEDKMWR 574
Query: 208 Q-SAVCGPQSSTWKLPILPRDHSWARS------WAYRDSLKAEENRKLQKMKDEQHQKSE 260
Q + + W+ R+ R W + ++ +E + ++ + + Q+ +
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 261 LLELKRQQQEQERAKIHQTE 280
+ E + QEQE Q E
Sbjct: 635 IREQEEMTQEQEEKMGEQEE 654
Score = 43.1 bits (100), Expect = 5e-04
Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 22/208 (10%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYKQKLKRE 139
++I EQE E W+E+ + + + E ++ RQ+++++ + K ++E
Sbjct: 538 EKIREQE----EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV---WRQE 590
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFRE--HQQYKTAEFLSKL 197
E +R ++E + + +KM Q EK + EEK + QE RE + Q+ T E K+
Sbjct: 591 EKIREQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257
+ + + + + W R R + + E+ R+ ++M EQ +
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMW------RQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Query: 258 K-----SELLELKRQQQEQERAKIHQTE 280
K ++ E + + QEQE Q E
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/232 (21%), Positives = 110/232 (47%), Gaps = 39/232 (16%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAE 243
E + + E + E ++ Q + W+ ++ R ++ + E
Sbjct: 348 EEKMRRQEEMM----WEKEEKMRRQ------EEMMWE-----KEEKMRR----QEEMMWE 388
Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295
+ K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 438
Score = 35.0 bits (79), Expect = 0.12
Identities = 39/198 (19%), Positives = 90/198 (45%), Gaps = 34/198 (17%)
Query: 81 QRIAEQELANLEK-WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
++I EQE EK W+++ + + + + E + ++Q + +Q + ++ ++E
Sbjct: 577 EKIREQE----EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENL--RREAFREHQQYKTAEFLSKL 197
E +R ++E + + +KM Q EK + EEK + QE R+E Q+ K E K+
Sbjct: 633 EKIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257
+ + + + W+ ++ E+ K+Q+ +++ +
Sbjct: 692 REQ-------EEMMQEQEEKMWE----------------QEEKMCEQEEKMQEQEEKMRR 728
Query: 258 KSELL---ELKRQQQEQE 272
+ E + E++ +QQE++
Sbjct: 729 QEEKMWEQEVRLRQQEEK 746
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
+ +A +H + +KL + + + W+ + W
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 316
Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282
++ E+ K+++ +++ ++ E++ K ++ ++ + + E +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 51.2 bits (121), Expect = 2e-06
Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 19/224 (8%)
Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
+++ +E+++A L+K E+ A+ + ++L + E + + K L+ QS+Y K+ +E
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY-LKISQE 528
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNT 199
+ + EE ELQK KAI E NKL + ++ E R + + L +
Sbjct: 529 KEQQESLALEELELQK-KAILTESENKLRDLQQEAETYRTRILELESSLEKS--LQENKN 585
Query: 200 ESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEEN----RKLQKMKDEQ 255
+S D + A + ++ ++ H +SLK +++ KLQ +K +
Sbjct: 586 QSKDLAVHLEAEKNKHNK--EITVMVEKHK-----TELESLKHQQDALWTEKLQVLKQQY 638
Query: 256 HQKSELLELKRQQQEQERAK----IHQTEHRRVNNAFLDRLQGK 295
+ E L K +Q+++ K I Q +N L++L K
Sbjct: 639 QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Score = 45.4 bits (106), Expect = 9e-05
Identities = 65/286 (22%), Positives = 129/286 (45%), Gaps = 39/286 (13%)
Query: 31 QGELSPVEDQREGLEAAPKGPSR---ESVVHAGQRRTSAYTL--IAPNINRRNEIQ-RIA 84
+ + S +E + LE K + E H Q+ +L + N N++ +I+ +
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 85 EQELANLEKWKEQ--NRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESV 142
Q+L + ++ E+ NR K E + + Q+ M+++ + K K E V
Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAE-----------EKILTLENQVYSMKAELETKKKELEHV 1611
Query: 143 RIKKEAEEAELQKMK-AIQREKSNKLEEKKR--------LQENLRREAFREHQQYK--TA 191
+ +++E EL+ ++ ++ E + KL E KR +++ L + + +QYK T
Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE 1671
Query: 192 EFLSKLNTESPDRS----ACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247
LS+LNT+ +R + + +SS + I+PR S AY + +A+
Sbjct: 1672 SHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR--SAKNVAAYTEQEEADSQGC 1729
Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293
+QK +E K +L+ ++E+ ++ Q + V++ F R Q
Sbjct: 1730 VQKTYEE---KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQ 1772
Score = 43.1 bits (100), Expect = 5e-04
Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 28/215 (13%)
Query: 82 RIAEQELA---NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKR 138
RI E E + +L++ K Q++ VHL + ++ T + +K + +L K++Q
Sbjct: 568 RILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALW 627
Query: 139 EESVRIKKEAEEAELQKMKA-IQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197
E +++ K+ + E++K++ ++EK L++K+ + F+ H + + L KL
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--------FQAHIEEMNEKTLEKL 679
Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257
+ + + + S + + KL + L +++ KMK E
Sbjct: 680 DVKQTELESLSSELSEVLKARHKL---------------EEELSVLKDQT-DKMKQELEA 723
Query: 258 KSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRL 292
K + + QQQ K H+ +R A D++
Sbjct: 724 KMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI 758
Score = 36.6 bits (83), Expect = 0.042
Identities = 45/219 (20%), Positives = 102/219 (46%), Gaps = 31/219 (14%)
Query: 68 TLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGG---SQSETEVRQKQQ 124
TL +++ ++++ E L + ++Q AK + + G + S E QK+Q
Sbjct: 969 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQ 1028
Query: 125 LQLMQSKYKQKLKREESVRIKKEAEEA-ELQKMKAIQ-REKSNKLEEKKRL-------QE 175
++ + ++++L S+ KK ++A ELQ++ IQ +EK ++ E K+ +E
Sbjct: 1029 IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1088
Query: 176 NLRRE-AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
+ +E + + + K L++L + +SA +++ ++ +
Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET---------------KLK 1133
Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQER 273
A+ + L+ + N+ L K+ + +L+ELK +E +R
Sbjct: 1134 AHLEKLEVDLNKSL---KENTFLQEQLVELKMLAEEDKR 1169
Score = 35.0 bits (79), Expect = 0.12
Identities = 50/262 (19%), Positives = 107/262 (40%), Gaps = 53/262 (20%)
Query: 34 LSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEK 93
LS +E Q LE G RE Q+ + ++ +++ +QEL L+K
Sbjct: 1918 LSNMEAQHNDLEFKLAGAEREK-----QKLGKEIVRLQKDLRM---LRKEHQQELEILKK 1969
Query: 94 WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES---VRIKK---E 147
+Q R + ++ Q + E++ L+ + ++ +L ++E + IK+ +
Sbjct: 1970 EYDQEREE-------KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINK 2022
Query: 148 AEEAELQKMKAIQREKSNKLEEKKRLQENLRREA--FREHQQYKTAEFLSKLNTESPDRS 205
A+E E + +++ Q E + L++ ++L+R A + E + E +K+
Sbjct: 2023 AQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLE 2082
Query: 206 ACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR-----KLQKMKDEQHQKSE 260
Q Y+ L+ EEN + +++ + QK+
Sbjct: 2083 ELQK-------------------------KYQQKLEQEENPGNDNVTIMELQTQLAQKTT 2117
Query: 261 LLELKRQQQEQERAKIHQTEHR 282
L+ + ++++ R +IH E R
Sbjct: 2118 LISDSKLKEQEFREQIHNLEDR 2139
Score = 29.3 bits (64), Expect = 6.8
Identities = 52/235 (22%), Positives = 102/235 (43%), Gaps = 38/235 (16%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQK 135
R+ I+++ Q L + KE++ + + L +Q E R+K + ++ Q K +K
Sbjct: 388 RSRIKQMTTQG-EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 136 LKREESVRI---------------KKEAEE--AELQKM--KAIQREKSNKLEEKKRLQEN 176
EE + + KK +EE A+LQK+ K + R K +L +K + +E
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 505
Query: 177 LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR---- 232
+E + + +E+L K++ E Q ++ + K IL + R
Sbjct: 506 EFQEQMKVALEKSQSEYL-KISQEKEQ----QESLALEELELQKKAILTESENKLRDLQQ 560
Query: 233 -SWAYRD---SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQE---RAKIHQTE 280
+ YR L++ + LQ+ K++ + LE ++ + +E + H+TE
Sbjct: 561 EAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE 615
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/208 (20%), Positives = 99/208 (47%), Gaps = 16/208 (7%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K +
Sbjct: 294 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 348
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187
+K++R+E + +KE + L++M + EK +LEEK R QE R+E + +Q
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247
K E +K+ + + + + W+ ++ R+ K +E +
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREEEKRQEQEE 463
Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAK 275
+ + +++ ++ E+ K + EQE+ +
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/259 (16%), Positives = 104/259 (40%), Gaps = 18/259 (6%)
Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
+ +Q + E K E + +R+ + R + ++I EQE + W++
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 442
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKM 156
+ + + + E RQ+++++ + ++QK K E +I+K+ E+ Q+
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502
Query: 157 KAIQREKSNKLEEKK--RLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGP 214
K +E+ + +E+K R +E +R + + +Q + ++ E ++ Q
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562
Query: 215 QSSTWKLPILPRD-------------HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSEL 261
Q + R+ + W + ++ +E ++ + Q+ ++
Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622
Query: 262 LELKRQQQEQERAKIHQTE 280
E + + QEQE Q E
Sbjct: 623 CEQEEKMQEQEEKMRRQEE 641
Score = 43.5 bits (101), Expect = 3e-04
Identities = 39/215 (18%), Positives = 102/215 (47%), Gaps = 30/215 (13%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQK 135
+ E R E+++ EK +EQ + Q E ++R++++ Q ++K ++Q+
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKR------------QEEEKIREQEKRQEQEAKMWRQE 422
Query: 136 LK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
K RE+ +I+++ ++ Q+ K ++EK + EEK++ QE + R+ + +Q +
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA------RSWAYRDSLKAEENRKL 248
K++ + R + W+ D + W + ++ E+ K+
Sbjct: 482 EKMHEQEKIRKQ--------EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR-EQEEKI 532
Query: 249 QKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
++ +++ ++ E+++ + ++ ++ K+ + E R
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/208 (22%), Positives = 90/208 (43%), Gaps = 12/208 (5%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135
R+ E R E+ EK EQ + + R + E + ++Q + M + ++
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEF 193
++EE +R ++E + E ++M Q EK + EEK + QE +RR E RE Q+ K E
Sbjct: 526 REQEEKIR-EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE-QEEKIREQ 583
Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253
K+ E ++ Q Q + + W + + +E + ++ +
Sbjct: 584 KEKIR-EQEEKIWEQEEKIREQEEMMQ-------EQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 254 EQHQKSELLELKRQQQEQERAKIHQTEH 281
+ Q+ ++ E + + ++QE EH
Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Score = 37.4 bits (85), Expect = 0.025
Identities = 48/234 (20%), Positives = 102/234 (43%), Gaps = 57/234 (24%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYR--DSLK 241
E + + E + W + R + +
Sbjct: 348 EEKMRRQEEMM-----------------------------------WEKEEKMRRLEEMM 372
Query: 242 AEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295
E+ K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 424
Score = 35.4 bits (80), Expect = 0.094
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 19/134 (14%)
Query: 77 RNEIQRIAEQE---LANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
R + ++I EQE EK EQ RR E E + ++Q + ++ + +
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 134 QKLKREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NL 177
+ ++EE +R ++E + + +KM Q EK + EEK R QE
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652
Query: 178 RREAFREHQQYKTA 191
+ E +EHQ++ A
Sbjct: 653 QEEKMQEHQEHLEA 666
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
+ +A +H + +KL + + + W+ + W
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 316
Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282
++ E+ K+++ +++ ++ E++ K ++ ++ + + E +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 50.4 bits (119), Expect = 3e-06
Identities = 58/236 (24%), Positives = 107/236 (45%), Gaps = 38/236 (16%)
Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGS------QSETEVRQKQQLQLMQ 129
++ E++ I A +E+ E+ R + + +++ + Q E E +Q+LQL +
Sbjct: 909 KKQELEEICHDLEARVEE--EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK 966
Query: 130 SKYKQKLKREESVRIKKEAEEAELQKMKAI--------------QREKSNKLEEKKR--- 172
+ KLK+ E +I E + +L K K + + EKS L + K
Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Query: 173 -----LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRD 227
L+E LRRE E Q+ + + KL +S D S Q A Q + K+ + ++
Sbjct: 1027 AMITDLEERLRRE---EKQRQELEKTRRKLEGDSTDLSD-QIAELQAQIAELKMQLAKKE 1082
Query: 228 HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
+ A + A++N L+K+++ + Q SEL ++ E ERA ++ E ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISEL----QEDLESERASRNKAEKQK 1134
Score = 37.0 bits (84), Expect = 0.032
Identities = 42/213 (19%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 79 EIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYKQKLK 137
E Q AE L +E + Q A+ + L + Q+ETE+ + ++L+ + KQ+L+
Sbjct: 859 EKQLAAENRLTEMETLQSQLMAEKLQLQEQL----QAETELCAEAEELRARLTAKKQELE 914
Query: 138 R---EESVRIKKEAE-----EAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYK 189
+ R+++E E +AE +KM+ +E +LEE++ ++ L+ E + K
Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 190 TAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQ 249
E + + + A + + + + + + + E+++ L
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE---------------EKSKSLA 1019
Query: 250 KMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282
K+K++ LE + +++E++R ++ +T +
Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQRQELEKTRRK 1052
Score = 33.1 bits (74), Expect = 0.47
Identities = 48/217 (22%), Positives = 93/217 (42%), Gaps = 37/217 (17%)
Query: 84 AEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKR----- 138
A+QEL + R + V+++ + L E + Q+Q M+ K+ Q ++
Sbjct: 1157 AQQELRS-------KREQEVNILKKTL----EEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
Query: 139 EESVRIKKEAEEAE----------LQKMKAIQREKSNKLEEKKRLQENLR--REAFREHQ 186
E++ R+K E+A+ ++K + + K + ++K+++ L+ + F E +
Sbjct: 1206 EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 187 QYKT--AEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAY-RDSLKAE 243
+ +T A+ ++KL E + + S S K L +D S S L E
Sbjct: 1266 RVRTELADKVTKLQVELDNVTGLLS------QSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280
ENR+ + + Q + R+Q E+E H E
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE 1356
Score = 32.3 bits (72), Expect = 0.80
Identities = 48/253 (18%), Positives = 102/253 (40%), Gaps = 49/253 (19%)
Query: 78 NEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK 137
+E+Q E E A+ K ++Q R LG + + L ++ + + K
Sbjct: 1114 SELQEDLESERASRNKAEKQKRD---------LGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 138 REESVRIKKEA-------EEAELQKMKAIQ----REKSNKLEEKKRLQENLRR------- 179
RE+ V I K+ EA++Q+M+ E + +LE+ KR++ NL +
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 180 ---------------EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPIL 224
+ EH++ K L +L + + ++ + KL +
Sbjct: 1225 ERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA---DKVTKLQVE 1281
Query: 225 PRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRV 284
+ + S + DS ++ + ++ + ELL+ + +Q+ K+ Q E +
Sbjct: 1282 LDNVTGLLSQS--DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK- 1338
Query: 285 NNAFLDRLQGKSQ 297
N+F ++L+ + +
Sbjct: 1339 -NSFREQLEEEEE 1350
Score = 31.6 bits (70), Expect = 1.4
Identities = 36/161 (22%), Positives = 68/161 (42%), Gaps = 42/161 (26%)
Query: 30 RQGELSPVEDQRE--------GLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81
R G L+ +E++R+ G +A +G Q++ +A ++ N
Sbjct: 764 RAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNC------- 816
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141
A +L N + W+ + KP+ LQ+ + + + K EE
Sbjct: 817 -AAYLKLRNWQWWRLFTKVKPL---------------------LQVSRQEEEMMAKEEEL 854
Query: 142 VRIKKE--AEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180
V+++++ A E L +M+ +Q S + EK +LQE L+ E
Sbjct: 855 VKVREKQLAAENRLTEMETLQ---SQLMAEKLQLQEQLQAE 892
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 3e-06
Identities = 43/223 (19%), Positives = 102/223 (45%), Gaps = 19/223 (8%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K +
Sbjct: 355 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 409
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187
+K++R+E + +KE + ++M + EK +LEEK R QE R+E + +Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKL--------PILPRDHSWARSWAYRDS 239
K E +K+ + + + + W+ I + + +R
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282
K E ++ + K++ H++ E + + ++ ++ K+H E +
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Score = 41.6 bits (96), Expect = 0.001
Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 42/229 (18%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQK 135
+ E R E+++ EK +EQ + Q E ++R++++ Q ++K ++Q+
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKR------------QEEEKIREQEKRQEQEAKMWRQE 483
Query: 136 LK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
K RE+ +I+++ E+ Q+ K ++EK + EEK++ QE + R+ + +Q +
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA------RSWAYRDSLKAEEN--- 245
K++ + + + + W+ D + W + ++ +E
Sbjct: 543 EKIHEQ-------EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 246 ------RKLQKMKDEQHQK-----SELLELKRQQQEQERAKIHQTEHRR 283
R+ ++M EQ +K ++ E + + QEQE Q E R
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/268 (21%), Positives = 110/268 (41%), Gaps = 20/268 (7%)
Query: 22 RDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81
R+ ++ Q ++ E++R+ E + R+ R+ I + E
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYK---QKLK 137
E+++ EK +E+ + + + R+ + + E+ RQK+++ + K + +K+
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 138 REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197
R+E +E + E ++ Q EK + EEK R QE RE Q+ T E K+
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE-----QEEMTQEQEEKM 615
Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257
E ++ Q Q + R R + + E+ R+ ++M EQ +
Sbjct: 616 G-EQEEKMCEQEEKMQEQEEKMR-----RQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669
Query: 258 K-----SELLELKRQQQEQERAKIHQTE 280
K ++ E + + QEQE Q E
Sbjct: 670 KMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Score = 37.7 bits (86), Expect = 0.019
Identities = 48/232 (20%), Positives = 105/232 (45%), Gaps = 53/232 (22%)
Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123
+ ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 354
Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183
L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E +
Sbjct: 355 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 408
Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAE 243
E + + E + W+ ++ R ++ + E
Sbjct: 409 EEKMRRQEEMM------------------------WE-----KEEKMRR----QEEMMWE 435
Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295
+ K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 485
Score = 36.6 bits (83), Expect = 0.042
Identities = 36/170 (21%), Positives = 77/170 (45%), Gaps = 28/170 (16%)
Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRL 173
Q E RQ+++++ + K +++ EE +R ++E + + +KM Q EK + EEK +
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQE 631
Query: 174 QENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARS 233
QE R Q+ K E K+ + + + + W+
Sbjct: 632 QEEKMR-----RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE------------- 673
Query: 234 WAYRDSLKAEENRKLQKMKDEQHQKSELL--ELKRQQQEQERAKIHQTEH 281
++ E+ K+Q+ +++ ++ E + + R +Q++E+ + HQ EH
Sbjct: 674 ---QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ-EH 719
Score = 35.4 bits (80), Expect = 0.094
Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 19/131 (14%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R + ++I EQE E+ ++ + Q E RQ+++++ + K +++
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ- 653
Query: 137 KREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NLRRE 180
EE +R ++E + + +KM Q EK + EEK R QE + E
Sbjct: 654 --EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 181 AFREHQQYKTA 191
+EHQ++ A
Sbjct: 712 KMQEHQEHLEA 722
Score = 34.3 bits (77), Expect = 0.21
Identities = 40/176 (22%), Positives = 73/176 (41%), Gaps = 43/176 (24%)
Query: 109 RLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLE 168
RL Q E RQ++++Q + K +++ EE +R ++E + +KM+ Q E + E
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEKMRR-QEEMMWEKE 409
Query: 169 EKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDH 228
EK R QE + E +E + + E +
Sbjct: 410 EKMRRQEEMMWE--KEEKMRRQEEMM---------------------------------- 433
Query: 229 SWARSWAYRD-SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
W + R+ K E K+++ ++E+ Q+ E + + ++QEQE Q E R
Sbjct: 434 -WEKEEKIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Score = 33.9 bits (76), Expect = 0.27
Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174
T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L
Sbjct: 260 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 319
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
+ +A +H + +KL + + + W+ + W
Sbjct: 320 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 377
Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282
++ E+ K+++ +++ ++ E++ K ++ ++ + + E +
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 50.4 bits (119), Expect = 3e-06
Identities = 51/247 (20%), Positives = 109/247 (44%), Gaps = 29/247 (11%)
Query: 34 LSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEK 93
+ P E +R+ LE + E + L + R ++++ Q +E+
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQ 586
Query: 94 WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAEL 153
KE+ + + + ++ +TE ++++L ++K K K+ E V +++ EE E
Sbjct: 587 MKEEKKKQ----IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-EA 641
Query: 154 QKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCG 213
++++ +Q+E EE++R QE L+++ E ++ + A +L + Q
Sbjct: 642 RRLRWLQQE-----EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE---- 692
Query: 214 PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQER 273
R R R+ + E+ R+L + E+ ++ E L+ +R+ QE+E+
Sbjct: 693 ------------RREQERREQERREQERREQERQLAEQ--ERRREQERLQAERELQEREK 738
Query: 274 AKIHQTE 280
A Q E
Sbjct: 739 ALRLQKE 745
Score = 42.4 bits (98), Expect = 8e-04
Identities = 65/301 (21%), Positives = 123/301 (40%), Gaps = 34/301 (11%)
Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61
+ NS PA+ P+ PS Q E DQ +G P+ R ++V +
Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462
Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121
+ + P ++ A + + L + + + + P S ++ +++
Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522
Query: 122 KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------KKR 172
L+ M K K++ +R E++R K+EAE+ QK ++ +K +LEE +K
Sbjct: 523 NTPLR-MDPKEKER-QRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLRKV 577
Query: 173 LQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSA---VCGPQSSTWKLPILP 225
LQ R E +E + + K A+ K +R A + A + +
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 226 RDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTEHR 282
+ + W ++ + LQK K+E+ ++ + E KR +Q+EQER + + E
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
Query: 283 R 283
R
Sbjct: 698 R 698
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ + E +R+AEQ +EQ R + R + E E R++Q+ QL + +
Sbjct: 671 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 719
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190
+R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K
Sbjct: 720 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776
Query: 191 AE 192
E
Sbjct: 777 KE 778
Score = 38.9 bits (89), Expect = 0.009
Identities = 25/115 (21%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
+ E + QEL +K +EQ R + R + E +++++ + + + +++
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 137 KREESVRIKKEAEEAELQKMKA----IQREKSNKLEEKKRLQENLRREAFREHQQ 187
+RE+ ++ ++ E ++++A +REK+ +L +K++LQ L + +E QQ
Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQ 761
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.3 bits (116), Expect = 6e-06
Identities = 47/231 (20%), Positives = 106/231 (45%), Gaps = 40/231 (17%)
Query: 24 PQDPSGRQGELSPVE----DQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNE 79
PQ P G QG L P + Q+ P+GP R+ ++ T + L +P + ++ +
Sbjct: 3792 PQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM------TQSRVLSSPQLAQQGQ 3845
Query: 80 IQR-----IAEQELANLEKWKEQNRAKPVHLVPRRLGGS----------------QSETE 118
A+Q+ + ++ + A HL + S Q + +
Sbjct: 3846 GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQ 3905
Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178
++Q+QQLQ Q +Q+L++++ ++ ++ ++ + Q+++ Q+++ + +++ + Q+ +
Sbjct: 3906 LQQQQQLQQQQ---QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962
Query: 179 REAFREHQQYKTAEFLSKLNT-ESPDRSACQSAVCGPQSSTWKLPILPRDH 228
++ F++ QQ + L++ T SP + Q GP +P P H
Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP-----GMPAKPLQH 4008
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 49.3 bits (116), Expect = 6e-06
Identities = 51/244 (20%), Positives = 108/244 (44%), Gaps = 29/244 (11%)
Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96
VE +R+ LE + E + L + R ++++ Q +E+ KE
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQMKE 593
Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKM 156
+ + + + ++ +TE ++++L ++K K K+ E V +++ EE E +++
Sbjct: 594 EKKKQ----IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-EARRL 648
Query: 157 KAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQS 216
+ +Q+E EE++R QE L+++ E ++ + A +L + Q
Sbjct: 649 RWLQQE-----EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE------- 696
Query: 217 STWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 276
R R R+ + E+ R+L + E+ ++ E L+ +R+ QE+E+A
Sbjct: 697 ---------RREQERREQERREQERREQERQLAEQ--ERRREQERLQAERELQEREKALR 745
Query: 277 HQTE 280
Q E
Sbjct: 746 LQKE 749
Score = 40.0 bits (92), Expect = 0.004
Identities = 63/303 (20%), Positives = 123/303 (40%), Gaps = 34/303 (11%)
Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61
+ NS PA+ P+ PS Q E DQ +G P+ R ++V +
Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462
Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121
+ + P ++ A + + L + + + + P S ++ +++
Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522
Query: 122 KQQLQLMQ--SKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------K 170
L++ S +++ +R E++R K+EAE+ QK ++ +K +LEE +
Sbjct: 523 NTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLR 579
Query: 171 KRLQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSA---VCGPQSSTWKLPI 223
K LQ R E +E + + K A+ K +R A + A + +
Sbjct: 580 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639
Query: 224 LPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTE 280
+ + W ++ + LQK K+E+ ++ + E KR +Q+EQER + + E
Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 281 HRR 283
R
Sbjct: 700 QER 702
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%)
Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
+ + E +R+AEQ +EQ R + R + E E R++Q+ QL + +
Sbjct: 675 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 723
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190
+R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K
Sbjct: 724 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780
Query: 191 AE 192
E
Sbjct: 781 KE 782
Score = 38.9 bits (89), Expect = 0.009
Identities = 25/115 (21%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
+ E + QEL +K +EQ R + R + E +++++ + + + +++
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711
Query: 137 KREESVRIKKEAEEAELQKMKA----IQREKSNKLEEKKRLQENLRREAFREHQQ 187
+RE+ ++ ++ E ++++A +REK+ +L +K++LQ L + +E QQ
Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQ 765
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/190 (26%), Positives = 96/190 (50%), Gaps = 18/190 (9%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKA---IQREKSNKLEEKKR 172
E E +Q+++L+ ++SK K + EE K+++++AEL++M+ QR+++ ++ + R
Sbjct: 597 EFERQQREELEKLESKRKLIEEMEE----KQKSDKAELERMQQEVETQRKETEIVQLQIR 652
Query: 173 LQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA 231
QE +L+R +F H + K + L++ +R Q + + + L
Sbjct: 653 KQEESLKRRSF--HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQ 710
Query: 232 RSWAYRDSLKAE------ENRKLQKMKDEQHQKSELLELKRQQQEQERAKI--HQTEHRR 283
R ++ KAE E +LQK KDEQ+ K EL + + ++QE+E+ + H E R
Sbjct: 711 RLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLR 770
Query: 284 VNNAFLDRLQ 293
+ L+
Sbjct: 771 EKQEMIQLLR 780
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 35/216 (16%)
Query: 89 ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEA 148
ANL+K KE + ++ R + + RQ+ +L+L++ +Q + +E V ++
Sbjct: 267 ANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLR---EQHAREKEEVVLRCGQ 323
Query: 149 EEAELQKMKAIQREKSNKL---------EEKKRLQENLRREAFREHQ----------QYK 189
E AEL++ + EK+ ++ EK ENLR+E +HQ Q +
Sbjct: 324 EAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKE 383
Query: 190 TAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQ 249
AE ++L D++ + A+ +S H A R+ L++E R L+
Sbjct: 384 LAEQRAELEKIFQDKNQAERALRNLES-----------HHQAAIEKLREDLQSEHGRCLE 432
Query: 250 --KMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
+ K ++ +K + LEL+ Q E K E R
Sbjct: 433 DLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIR 468
Score = 38.9 bits (89), Expect = 0.009
Identities = 51/205 (24%), Positives = 95/205 (46%), Gaps = 24/205 (11%)
Query: 85 EQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRI 144
+QE+ LE Q AKP PR + + EV +L+Q K ++KL + I
Sbjct: 1496 QQEIQRLEGQLRQ-AAKPQPWGPRDSQQAPLDGEV------ELLQQKLREKLDEFNELAI 1548
Query: 145 KKEA-------EEAELQKMKAIQ---REKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194
+KE+ +E E+++++ + R+K +L+E+ Q+N+ + ++ + K + +
Sbjct: 1549 QKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQ-M 1607
Query: 195 SKLNTESPDRSACQSAVC--GPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMK 252
S L S +S + C P S + P + + + R+ R+S + +L+KMK
Sbjct: 1608 SSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEVT-QRALLRRESEVLDLKEQLEKMK 1666
Query: 253 DEQHQKSE---LLELKRQQQEQERA 274
+ K+E L LK Q + A
Sbjct: 1667 GDLESKNEEILHLNLKLDMQNSQTA 1691
Score = 35.8 bits (81), Expect = 0.072
Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKRE--ESVRIKKEAEEAELQKMKAIQREKSNKLEE 169
GS+ +T + +K++ +QS Q +E ES+ ++ + + ++Q++K S+++EE
Sbjct: 1059 GSEKKTALHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEE 1118
Query: 170 KKRLQENLRREAFREHQQYKTAEFLSKL----NTESPDRSACQSAV 211
+ E L++ RE + + A LS L N +R A Q A+
Sbjct: 1119 CRSELEVLQQR--RERENREGANLLSMLKADVNLSHSERGALQDAL 1162
Score = 32.7 bits (73), Expect = 0.61
Identities = 40/182 (21%), Positives = 90/182 (49%), Gaps = 17/182 (9%)
Query: 113 SQSETEVRQK-QQLQLMQSK---YKQKLKREESVRIKKEAEEAE-LQKMKA---IQREKS 164
S E E++ Q+L+ Q K + +L+ E+ +++E++ A+ L++++A QR +S
Sbjct: 2642 SSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQS 2701
Query: 165 NKL----EEKKRLQENLRREAFREHQQYKT--AEFLSKLNTESPDRSACQSAVCGPQSST 218
++L + ++ ++NL++E EH + + A+ S+L+ D +A +S +
Sbjct: 2702 SRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEAL 2761
Query: 219 WKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQ 278
+L S A + LQK+K+E KS +++L+ ++ ++ +H
Sbjct: 2762 RHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEE---KSRVVDLQAMLEKVQQQALHS 2818
Query: 279 TE 280
+
Sbjct: 2819 QQ 2820
Score = 31.6 bits (70), Expect = 1.4
Identities = 46/231 (19%), Positives = 88/231 (38%), Gaps = 33/231 (14%)
Query: 69 LIAPNINRRNE---IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL 125
L+ +++R + + + + A L+K KE+ R+ Q+ E Q+Q L
Sbjct: 2766 LLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKS---------RVVDLQAMLEKVQQQAL 2816
Query: 126 QLMQSKYKQKLKREESVRIKKEAE---EAELQKMKAIQREKSNKLEEKKRLQENLRREAF 182
Q + K E++R +KE ++ ++ + +RE LE ++ L+ E
Sbjct: 2817 HSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELE 2876
Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKA 242
+ H + K E + R + +A W+ W R L+
Sbjct: 2877 QSHPRLKEQEGRKAARRSAEARQSPAAA------EQWR--------KWQRDKEKLRELEL 2922
Query: 243 EENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293
+ R L K+K Q +L + E +++H RR + D L+
Sbjct: 2923 QRQRDLHKIKQLQQTVRDL----ESKDEVPGSRLHLGSARRAAGSDADHLR 2969
Score = 30.4 bits (67), Expect = 3.0
Identities = 36/175 (20%), Positives = 77/175 (44%), Gaps = 35/175 (20%)
Query: 118 EVRQKQQLQLMQSKYKQKL------------KREESVRIKKEAEEAELQKMKAIQREKSN 165
E K QL L+Q++ K+++ K + R+K + E+ + ++ Q+E +N
Sbjct: 674 ETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNN 733
Query: 166 KLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILP 225
K+ E +++E R+ +K + +L E+ ++ ++ + K I+
Sbjct: 734 ----AKQKTELMKQEFQRKETDWKVMK--EELQREAEEKLTLMLLELREKAESEKQTII- 786
Query: 226 RDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280
+ L+ E R+LQ Q +++L+L+R EQ+ ++ Q E
Sbjct: 787 ----------NKFELREAEMRQLQ-----DQQAAQILDLERSLTEQQ-GRLQQLE 825
Score = 30.0 bits (66), Expect = 4.0
Identities = 36/173 (20%), Positives = 70/173 (40%), Gaps = 6/173 (3%)
Query: 107 PRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNK 166
P G + V++ LQLM ++ + +R+E ++A LQ+ + +
Sbjct: 844 PTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQL 903
Query: 167 LEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPR 226
L+E+ + Q Q E + L ++ A + A + + L L
Sbjct: 904 LQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAA-DLGALET 962
Query: 227 DHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQT 279
H + DSL++ + Q +++E Q ELL ++Q ++ +HQT
Sbjct: 963 RHL-----SSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQT 1010
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/181 (20%), Positives = 84/181 (46%), Gaps = 14/181 (7%)
Query: 92 EKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEA 151
EK +E+ R + R E E + ++Q + MQ + ++ ++EE K + +E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE----KMQEQEE 638
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
++ + + E+ K+ E++RL E ++E EH++ + E + + + ++ +
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Query: 212 CGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQ 271
+ TW + + S + ++ R+ ++M EQ +K + E K Q+QE+
Sbjct: 697 QEQEKKTWDQEKMREEESMRE--------REKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Query: 272 E 272
E
Sbjct: 749 E 749
Score = 46.2 bits (108), Expect = 5e-05
Identities = 45/210 (21%), Positives = 93/210 (44%), Gaps = 16/210 (7%)
Query: 76 RRNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133
R+ E R E+++ E+ W+++ R R G E E + +Q + ++ + K
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERL-------REQEGKMREQEEKMWRQEKRLREQEK 328
Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ-ENLRREAFREHQQYKTAE 192
+ ++E+ +R +KE E E Q + Q EK + EEK R Q E + R+ R +Q K
Sbjct: 329 ELREQEKELREQKELREQEEQMQE--QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 193 FLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMK 252
+ + +R Q + + ++ W + R+ K +E K + +
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMR----EQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 253 DEQHQKSELLELKRQQQEQERAKIHQTEHR 282
+E+ Q+ E + + ++ +E + + E +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEK 472
Score = 45.4 bits (106), Expect = 9e-05
Identities = 41/207 (19%), Positives = 91/207 (43%), Gaps = 26/207 (12%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
++I EQE +EK ++ K R S E E + +++ ++M+ + ++ ++EE
Sbjct: 684 EKIWEQE--KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL------ 194
K + +E E+ + + E+ K+ E++RL E ++E EH++ + E +
Sbjct: 742 ----KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKIWEQEEK 795
Query: 195 -----SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARS---WAYRDSLKAEENR 246
K+ + + + G + W + W + W + + +E +
Sbjct: 796 MRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG----QEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 247 KLQKMKDEQHQKSELLELKRQQQEQER 273
+KM+ ++ + E E R Q+E+ R
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMR 878
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/221 (19%), Positives = 96/221 (43%), Gaps = 39/221 (17%)
Query: 82 RIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139
R EQ++ + E+ W++ R + + E +R+++++ K +++ K +
Sbjct: 386 REQEQKMRDQEERMWEQDERLR------------EKEERMREQEKMWEQVEKMREEKKMQ 433
Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEK---------KRLQENLRREAFREHQQYKT 190
E + ++ EE ++ + +REK + EE+ ++ +EN+ + +E QQ +
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 191 AEFLSKL------------NTESPDRSACQSAVCGPQSSTWKLPIL--PRDHSWARSWAY 236
E KL E ++ Q + G + W+ + D W +
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 237 RDSLKA--EENRKLQKMKDEQHQKSELLELKRQQQEQERAK 275
RD + ++ +++K EQ +K+ E K +++E+ R +
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 25/174 (14%)
Query: 116 ETEVRQKQQLQLMQSK---YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKR 172
+ E R +++ Q + K ++K++ EE +R ++E + E ++M Q EK + EEK +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 173 LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR 232
QE E Q+ K E K+ + + + + W+ LP +
Sbjct: 621 EQEEKMWE-----QEEKMQEQEEKMWEQ-------EEKMWEQEEKMWEQQRLPEQKE--K 666
Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQ---ERAKIHQTEHRR 283
W + K +E K+Q+ ++E+ + E +E K Q+QE+ ++ K+ + E R
Sbjct: 667 LWEHE---KMQEQEKMQE-QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Score = 38.5 bits (88), Expect = 0.011
Identities = 33/174 (18%), Positives = 75/174 (43%), Gaps = 11/174 (6%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175
E E + +Q + M+ + ++ +EE + K + +E + + RE+ E +K+++E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 176 N----LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA 231
+E + Q+ K E K+ + + + + W+ + W
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE----QEEKMWE 656
Query: 232 RSWAYRDSLKAEENRKLQKMKDEQHQKSELLE---LKRQQQEQERAKIHQTEHR 282
+ K E+ K+Q+ + Q Q+ ++ E ++++ QEQE+ Q + R
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Score = 32.7 bits (73), Expect = 0.61
Identities = 33/169 (19%), Positives = 73/169 (43%), Gaps = 7/169 (4%)
Query: 121 QKQQLQLMQSKYKQKLKREE----SVRIKKEAEEAELQKMKAIQREKSNKLEEKK--RLQ 174
+K ++QL + K+KL+R + V+ EE Q+ + ++EK + +E+K R +
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234
E LR + + +Q + K E Q Q + ++ + W
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE-EKMW 358
Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
+ ++ +E + ++ + Q+ ++ E +++ ++QE Q E R
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 407
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 23/169 (13%)
Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVR-----IKKEAEEAELQKMK-AIQREKSNKL 167
+ E + ++Q ++ Q + ++KL EE+ R + K EE EL+K K I+RE ++
Sbjct: 103 EEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEE-ELEKRKDEIEREVLRRV 161
Query: 168 EEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRD 227
EE KR+ E ++ E ++ + AE ++ E +R+ + IL +
Sbjct: 162 EEAKRIME---KQLLEELERQRQAELAAQKAREEEERAKREELE----------RILEEN 208
Query: 228 HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 276
+ R A + AEE ++ + + + H++ LE +RQ+Q++E KI
Sbjct: 209 N---RKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKI 254
Score = 31.6 bits (70), Expect = 1.4
Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 7/133 (5%)
Query: 163 KSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLP 222
KS+K +K+ + R+ R ++ K+ E ES RS + + +
Sbjct: 16 KSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERA 75
Query: 223 ILPRDHS--WARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280
P D + R+ + R SL ++ R+ ++ K E ++ ++ +QQE E I +
Sbjct: 76 SSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKI-----RQQEIEEKLIEEET 130
Query: 281 HRRVNNAFLDRLQ 293
RRV R++
Sbjct: 131 ARRVEELVAKRVE 143
Score = 31.2 bits (69), Expect = 1.8
Identities = 43/200 (21%), Positives = 82/200 (41%), Gaps = 16/200 (8%)
Query: 3 TRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQR 62
+R+R ++ S R P R +R L+ K E ++
Sbjct: 54 SRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQ 113
Query: 63 RTSAYTLIAPNINRRNEIQRI----AEQELANLEKWKEQNRAKPVHLVP--RRLGGSQSE 116
R I + +R+ A++ LEK K++ + + V +R+ Q
Sbjct: 114 RKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLL 173
Query: 117 TEVRQKQQLQLMQSKYKQ---KLKREESVRIKKEAEE--AELQKMKAIQR----EKSNKL 167
E+ +++Q +L K ++ + KREE RI +E AE Q A ++ E+ K+
Sbjct: 174 EELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKI 233
Query: 168 -EEKKRLQENLRREAFREHQ 186
EE+ +L++ +R+ E +
Sbjct: 234 HEERMKLEQERQRQQKEEQK 253
Score = 29.3 bits (64), Expect = 6.8
Identities = 36/211 (17%), Positives = 84/211 (39%), Gaps = 18/211 (8%)
Query: 90 NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE 149
N ++ + ++R++ V +R +S+ R++ + + + + + R +
Sbjct: 21 NKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPD 80
Query: 150 EAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQS 209
++ +R + L+EK++ +E ++ F ++ + E KL E R +
Sbjct: 81 RIDIFGRTVSKR---SSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEEL 137
Query: 210 AVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL----QKMKDEQHQKSELLELK 265
+ K + R+ L+ E K Q +++ + Q+ L +
Sbjct: 138 VAKRVEEELEK----------RKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQ 187
Query: 266 RQQQEQERAKIHQTEH-RRVNNAFLDRLQGK 295
+ ++E+ERAK + E NN + Q K
Sbjct: 188 KAREEEERAKREELERILEENNRKIAEAQAK 218
>gi|157266264 pleckstrin homology-like domain, family B, member 3
[Homo sapiens]
Length = 640
Score = 47.8 bits (112), Expect = 2e-05
Identities = 71/290 (24%), Positives = 122/290 (42%), Gaps = 36/290 (12%)
Query: 14 ASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAP----------KGPSRESVVHAGQR- 62
A P+SR + Q GE S E R+ EA P SRE V A +R
Sbjct: 42 AEPSSRGGAEQQAEEEEVGEGSSTESSRDAPEATPPIAMAATPPASTSSREGVRGAARRL 101
Query: 63 ---RTSAYTLIAPNINRRNEIQRIAEQ-------ELANL--EKWKEQNRAKPVHLVPRRL 110
+ A T +A R E+QR ++ E+A L E E+ A+ R L
Sbjct: 102 QGQQLEALTRVALMEQRVKELQRQRKELRIEMEVEVALLRGELAGERVAARREEEQLREL 161
Query: 111 GGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK 170
Q+ +E R +QQ + Q + Q+ R E +R + + +L QRE+ + ++
Sbjct: 162 LEQQAASEQRGRQQREQEQRRLSQERDRLEGLRQRLRKAQGQLDSQPEDQRERLLQGVQE 221
Query: 171 KRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSW 230
R Q ++ + A+ E +++ E S+ E D GPQ K+ L +
Sbjct: 222 MREQLDVAQRAY-EDLEFQQLERESRQEEEDRDSP-------GPQVPDPKVQELQASMAQ 273
Query: 231 ARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ----EQERAKI 276
R A + ++ E +L+ + ++ +S L K+++ QER+++
Sbjct: 274 HRRGALQHRIRVLE-EQLKSLGEQMAAESRGLSRKKEEALQALSQERSRL 322
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/216 (22%), Positives = 96/216 (44%), Gaps = 17/216 (7%)
Query: 77 RNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGS-QSETEVRQKQQLQLMQSK-- 131
+ E R EQ++ + E+ W++ R + R Q E ++R++++ Q + K
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 132 -YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQEN--LRREAFREHQQY 188
++K++ EE +R ++E + E ++M Q EK + EEK R QE +E + Q+
Sbjct: 551 DQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 189 KTAEFLSKL-NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247
K E K+ E D+ Q + Q + + W + ++ +E +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ-------EQEEKMWEQEEKMREQEEKM 662
Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
++ + Q Q+ ++ E + + Q QE Q E R
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/184 (21%), Positives = 86/184 (46%), Gaps = 26/184 (14%)
Query: 114 QSETEVRQKQQLQLMQSK-YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKR 172
+ + +R+K++ Q K ++Q+ K +E RI++ E ++++ + RE+ K++ +
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIRER--EKKMREEEETMREQEEKMQ---K 417
Query: 173 LQENLRREAFREHQQYKTAEFLSKL------------NTESPDRSACQSAVCGPQSSTWK 220
+EN+ + +E QQ + E KL E ++ Q + G + W+
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 221 LPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE--QERAKIHQ 278
+ + W + ++ +E QKM D++ + E E R+++E +E+ K+ Q
Sbjct: 478 QEKMREQED--QMWEQEEKMRDQE----QKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 279 TEHR 282
E +
Sbjct: 532 QEEK 535
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/194 (20%), Positives = 87/194 (44%), Gaps = 20/194 (10%)
Query: 92 EKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEA 151
E W+++ + R+ Q E RQ+++L+ + K ++ +EE +R +E
Sbjct: 235 EMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEGKMRE---QEEKMR----RQEK 283
Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211
L++ + RE+ +L E+K+L+E +E + Q+ K E K+ + + +
Sbjct: 284 RLREQEKELREQEKELREQKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Query: 212 CGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR-----KLQKMKDEQHQKSELLELKR 266
+ + RD R W + L+ +E R K+ + +++ ++ + E ++
Sbjct: 341 WEQEKQMREQEQKMRDQE-ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 267 QQQEQERAKIHQTE 280
+ +E+E Q E
Sbjct: 400 KMREEEETMREQEE 413
Score = 40.0 bits (92), Expect = 0.004
Identities = 52/229 (22%), Positives = 105/229 (45%), Gaps = 34/229 (14%)
Query: 68 TLIAPNINRRN-EIQ---RIAEQELANLE---KWKEQNRAKPVHLVPRRLGGSQSETEVR 120
T+ + ++N E+Q R+AE E + ++ K ++ + L+P+ + E R
Sbjct: 179 TITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 238
Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQRE-KSNKLEEKKRLQENLRR 179
Q+++L RE+ +I+K+ E+ Q+ + ++E K + EEK R QE R
Sbjct: 239 QEEEL------------REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 180 EAFRE-HQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRD 238
E +E +Q K KL + + + + W+ R+ + W +
Sbjct: 287 EQEKELREQEKELREQKKLREQ-------EEQMQEQEEKMWEQEEKMREQE-EKMWRQEE 338
Query: 239 SLKAEENR---KLQKMKDEQHQKSELLELKRQQQE--QERAKIHQTEHR 282
L +E + + QKM+D++ + E E R+++E +E+ K+ + E +
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387
Score = 35.4 bits (80), Expect = 0.094
Identities = 37/230 (16%), Positives = 98/230 (42%), Gaps = 43/230 (18%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQKLKRE 139
QR+ EQ+ E+ K Q + + + + E ++R ++++ + K ++Q+ RE
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIW---------EQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 140 ESVRIKKEAEEAELQKMKAI--------QREKSNKLEEKKRLQENLRREAFREHQQYKTA 191
+ ++ ++ E+ Q+ K Q E+ + EE+ R Q+ + ++ + ++ KT
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTW----KLPILPRDHSWARSWAYRDSLKAEENRK 247
E + TW K+ R + + + E+ K
Sbjct: 544 E---------------------QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQ 297
+Q+ +++ ++ E + + ++ +++ K+ + E + D++Q + +
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Score = 32.7 bits (73), Expect = 0.61
Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 14/182 (7%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136
R E + + EQE +++ +E+ R + + + + E ++ ++++ Q + +
Sbjct: 570 REEEEMMREQE-EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196
++EE + ++E + + +KM Q EK + EEK R QE + Q+ K E K
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEK-----MQGQEEKMREQEEK 682
Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA---RSWAYRDSLKAEENRKLQKMKD 253
+ + + + G + W + W + W + + EE + QK K
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWG----QEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Query: 254 EQ 255
++
Sbjct: 739 QE 740
Score = 32.7 bits (73), Expect = 0.61
Identities = 24/112 (21%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140
+++ EQE + W+++ + + R E + ++Q + MQ + ++ ++EE
Sbjct: 639 EKMQEQEE---KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 141 SVRIKKEAEEAELQKM-----KAIQREKSNKLEEKKRLQENLRREAFREHQQ 187
+R ++E + +KM K +E+ + EE+ R Q+ +E EH++
Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 31.2 bits (69), Expect = 1.8
Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175
E E + ++Q + MQ + ++ ++EE ++ ++E + +KM+ Q EK EEK QE
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG-QEEKMWGQEEKMWGQE 715
Query: 176 NLR--REAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQS 216
+E RE ++ + + K+ P+ S C P S
Sbjct: 716 EKMWGQEEMREKEE-RIRDQKEKMQERLPEHEERCSEPCLPPS 757
>gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform 4
[Homo sapiens]
Length = 522
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 150 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 209
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232
+ L +EA E QQ L+++ D R A ++ + QS PR H +
Sbjct: 210 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 262
Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
A R ++AE +L ++ QH + E Q + Q +H E RR
Sbjct: 263 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311
>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
[Homo sapiens]
Length = 695
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 323 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 382
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232
+ L +EA E QQ L+++ D R A ++ + QS PR H +
Sbjct: 383 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 435
Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
A R ++AE +L ++ QH + E Q + Q +H E RR
Sbjct: 436 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 484
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 379 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 438
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232
+ L +EA E QQ L+++ D R A ++ + QS PR H +
Sbjct: 439 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 491
Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
A R ++AE +L ++ QH + E Q + Q +H E RR
Sbjct: 492 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174
ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + +
Sbjct: 379 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 438
Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232
+ L +EA E QQ L+++ D R A ++ + QS PR H +
Sbjct: 439 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 491
Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283
A R ++AE +L ++ QH + E Q + Q +H E RR
Sbjct: 492 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540
>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
Length = 968
Score = 46.6 bits (109), Expect = 4e-05
Identities = 54/238 (22%), Positives = 111/238 (46%), Gaps = 35/238 (14%)
Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSET-EVRQKQ-----QLQLMQS 130
+NE++++ Q+ K K + + L+ R Q E E+ K+ + ++
Sbjct: 665 KNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDK 724
Query: 131 KYKQKLKREESVRIKK----EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQ 186
+ + +K++E +R ++ E EE +LQ+ + +++ L+++ LQ R E R+H+
Sbjct: 725 ERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQ---LKDQYFLQ---RHELLRKHE 778
Query: 187 QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLK----- 241
K E + + N ++ + Q +LP + R R Y+ SL
Sbjct: 779 --KEREQMQRYNQRMIEQLKVRQ-----QQEKARLPKIQRSEGKTRMAMYKKSLHINGGG 831
Query: 242 --AEENRKLQK--MKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295
AE+ K+++ ++E+ QKSE L+ +++ + Q R + Q E N + L +LQ +
Sbjct: 832 SAAEQREKIKQFSQQEEKRQKSERLQQQQKHENQMRDMLAQCES---NMSELQQLQNE 886
Score = 36.6 bits (83), Expect = 0.042
Identities = 57/289 (19%), Positives = 117/289 (40%), Gaps = 61/289 (21%)
Query: 52 SRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLG 111
+R+ VV + + +I+ + + E++ + QEL L +++
Sbjct: 530 TRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEH------------ 577
Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK 171
+++T++ K +LQL Q + E+ + KK+ + EL+ ++ Q+++ K+E+
Sbjct: 578 --RNQTQLSNKHELQLEQ----MHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDH 631
Query: 172 --RLQENLRREAFREHQQYKTAEFLSKLNTES--------PDRSACQSAVCGPQSSTWKL 221
R +E RR + + Y + KL + P + +S + T K
Sbjct: 632 AVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKK 691
Query: 222 PILPRDHSWARSWAYRDSLK--AEENRK---------LQKMKD------------EQHQK 258
+L RD + ++K +NR+ L K ++ E+HQ
Sbjct: 692 QLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEMEEHQL 751
Query: 259 SELLELKRQQ-------QEQERAKIHQTEH---RRVNNAFLDRLQGKSQ 297
E +L +QQ Q E + H+ E +R N +++L+ + Q
Sbjct: 752 QERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQ 800
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,101,017
Number of Sequences: 37866
Number of extensions: 763533
Number of successful extensions: 10255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 657
Number of HSP's that attempted gapping in prelim test: 5373
Number of HSP's gapped (non-prelim): 3403
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.