BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sapiens] (410 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sap... 821 0.0 gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo sap... 603 e-173 gi|148746195 trichohyalin [Homo sapiens] 66 7e-11 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 64 2e-10 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 64 2e-10 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 64 2e-10 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 64 2e-10 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 62 1e-09 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 55 1e-07 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 55 1e-07 gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 54 2e-07 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 6e-07 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 51 2e-06 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 2e-06 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 3e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 3e-06 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 50 3e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 6e-06 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 6e-06 gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 49 1e-05 gi|81295809 pericentrin [Homo sapiens] 48 1e-05 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 2e-05 gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 48 2e-05 gi|157266264 pleckstrin homology-like domain, family B, member 3... 48 2e-05 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 3e-05 gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05 gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05 gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 47 4e-05 gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 47 4e-05 gi|126362971 serine/threonine kinase 10 [Homo sapiens] 47 4e-05 >gi|50428917 epithelial stromal interaction 1 isoform 1 [Homo sapiens] Length = 410 Score = 821 bits (2120), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60 Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120 Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240 Query: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG Sbjct: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300 Query: 301 LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT 360 LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT Sbjct: 301 LEQSGGCWNMNSGNSWGSLLVFSRHLRVYEKILTPIWPSSTDLEKPHEMLFLNVILFSLT 360 Query: 361 VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF 410 VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF Sbjct: 361 VFTLISTAHTLDRAVRSDWLLLVLIYACLEELIPELIFNLYCQGNATLFF 410 >gi|15147248 epithelial stromal interaction 1 isoform 2 [Homo sapiens] Length = 307 Score = 603 bits (1555), Expect = e-173 Identities = 306/317 (96%), Positives = 306/317 (96%), Gaps = 11/317 (3%) Query: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG Sbjct: 1 MNTRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAG 60 Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR Sbjct: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120 Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE Sbjct: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSL 240 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST WARSWAYRDSL Sbjct: 181 AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSST-----------WARSWAYRDSL 229 Query: 241 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 300 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG Sbjct: 230 KAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGG 289 Query: 301 LEQSGGCWNMNSGNSWG 317 LEQSGGCWNMNSGNSWG Sbjct: 290 LEQSGGCWNMNSGNSWG 306 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 65.9 bits (159), Expect = 7e-11 Identities = 55/206 (26%), Positives = 103/206 (50%), Gaps = 10/206 (4%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL---QLMQSKYK 133 R E Q EQ+L ++ + + R K R +SE ++R++Q+ QL++ + + Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE 555 Query: 134 QKLKREE-SVRIKKEAEEA--ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKT 190 ++L++E R+K+E EE +L K + +R++ K E+++RL++ L+RE +Q + Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615 Query: 191 AEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQK 250 E +L E P+ Q + + + L R+ R R + EE R Q+ Sbjct: 616 RE--QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE--QRLKREEEEERLEQR 671 Query: 251 MKDEQHQKSELLELKRQQQEQERAKI 276 +K E ++ EL ++QEQ R +I Sbjct: 672 LKREHEEERREQELAEEEQEQARERI 697 Score = 57.0 bits (136), Expect = 3e-08 Identities = 52/230 (22%), Positives = 103/230 (44%), Gaps = 15/230 (6%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136 R E Q + E E L + Q R + ++L + E + Q++Q QL + + ++K Sbjct: 1670 REEEQLLQEGEEQQLRR---QERDRKFREEEQQLRRQERERKFLQEEQ-QLRRQELERKF 1725 Query: 137 KREESVRIKKEAEEAELQKM--KAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194 + EE +R + E E+ Q+ K ++ E+ E+++L+ R FRE +Q + Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785 Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254 +L ++ DR + + +L RD + W E+ ++L++ +D Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY--RWEEEQLQLEEQEQRLRQERDR 1843 Query: 255 QHQKSELL----ELKRQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQ 297 Q++ E + +R++QE +E K Q R++ + R Q + Q Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893 Score = 56.2 bits (134), Expect = 5e-08 Identities = 65/266 (24%), Positives = 116/266 (43%), Gaps = 24/266 (9%) Query: 25 QDPSGRQGELSPVEDQ---REGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81 Q G + E P E+Q RE LE KG E +R+ + R+ E Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKG-REEKQQQRRERQDRVFQEEEEKEWRKRETV 252 Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141 E+E E+ + Q + R+L + E ++++Q Q Q+L+RE+ Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ-------QRLRREQQ 305 Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEK-----KRLQENLRREAFREHQQYKTAEFLSK 196 +R K+E E E Q+ + Q+E+ + EE+ +R QE R + R Q+ + E + Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE--QQ 363 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256 L E + Q + + L R+ R R + ++ R+ Q+++ EQ Sbjct: 364 LRREQEEERREQQ--LRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQLRREQQ 418 Query: 257 QKSELLELKRQQQEQERAKIHQTEHR 282 + E +L+R+Q+E+ + H+ E R Sbjct: 419 LRRE-QQLRREQEEERHEQKHEQERR 443 Score = 54.7 bits (130), Expect = 2e-07 Identities = 65/293 (22%), Positives = 123/293 (41%), Gaps = 37/293 (12%) Query: 38 EDQREGLEAAPKGPSRESVVHAGQR--RTSAYTLIAPNINRRNEIQRIAEQELANLEKWK 95 E++RE E + RE QR R + + +++R E+ L K + Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553 Query: 96 EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQK 155 E+ R + RR + E E R+ Q L+ + + +Q+LKRE+ R+++ + E+++ Sbjct: 554 EEKRLEQ----ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609 Query: 156 M----KAIQREKSNKLEEKKRL-------QENLRREAFREHQQYKTAEFLSKLNTE---- 200 + + QR K + EE++R QE R++ R QQ + + L + E Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669 Query: 201 -----SPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR--------K 247 + + + + + I R W W A +++ + Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKW--QWQLESEADARQSKVYSRPRKQE 727 Query: 248 LQKMKDEQHQKSELLELKRQQQEQERA-KIHQTEHRRVNNAFLDRLQGKSQPG 299 Q+ + EQ +K E + Q QE+ERA + Q E +R + + + + KS+ G Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780 Score = 54.3 bits (129), Expect = 2e-07 Identities = 58/267 (21%), Positives = 122/267 (45%), Gaps = 38/267 (14%) Query: 26 DPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAE 85 +P RQ E P + +R+ K +E + G+ ++ + + + QR E Sbjct: 123 EPRDRQLEEEPGQRRRQ------KRQEQERELAEGEEQSEKQERL-----EQRDRQRRDE 171 Query: 86 QELANLEKWKEQNRAKPVHLVPRRLGGSQSET-----EVRQKQQLQLMQS--KYKQKLKR 138 + ++W+E+ + + G ++E ++R+++ L+L + + KQ+ +R Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231 Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198 E R+ +E EE E +K + + R++ KL+E++ ++ RE E +Q + E +L Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ---RELQEEEEQLRKLE-RQELR 287 Query: 199 TESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK 258 E + Q L R+ R + EE R+ Q+ +++Q ++ Sbjct: 288 RERQEEEQQQQR-------------LRREQQLRRKQEEERREQQEERREQQERREQQEER 334 Query: 259 SELLELKRQQQE--QERAKIHQTEHRR 283 E +L+R+Q+E +++ + Q E RR Sbjct: 335 REQ-QLRREQEERREQQLRREQEEERR 360 Score = 53.5 bits (127), Expect = 3e-07 Identities = 57/232 (24%), Positives = 108/232 (46%), Gaps = 35/232 (15%) Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQ 134 R +++R E+E + +EQ + L RR + E ++R++QQL+ Q + +Q Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQ 417 Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194 +L+RE+ +R ++E E E QK + +RE+ K E+++R R E H+Q + + L Sbjct: 418 QLRREQQLRREQEEERHE-QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476 Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254 + E R W + + + ++ R+ Q+++ E Sbjct: 477 KRDQEEE------------------------RRERWLK--LEEEERREQQERREQQLRRE 510 Query: 255 QHQKSELLELKRQQQE---QERAKIHQTEHRRVNNAFLDRLQGKSQPGGLEQ 303 Q ++ E LKRQ++E Q+R + Q + RR ++L + + LEQ Sbjct: 511 QEERRE-QRLKRQEEEERLQQRLRSEQ-QLRREQEERREQLLKREEEKRLEQ 560 Score = 52.4 bits (124), Expect = 7e-07 Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 47/215 (21%) Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVR 120 +RR + Y A R E Q + E+E + +E+ R + + E + R Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ------------EQERQYR 931 Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL---EEKKRLQENL 177 +++QLQ + +++L REE + +++ E + +K K +Q+++ L EK+R QE Sbjct: 932 EEEQLQ----QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-- 985 Query: 178 RREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYR 237 R + +RE ++ + E +L E ++ R W R + + Sbjct: 986 REKKYREEEELQQEE--EQLLREEREKR--------------------RRQEWERQYRKK 1023 Query: 238 DSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQE 272 D L+ EE + L+ E+ +K L E +RQ +E+E Sbjct: 1024 DELQQEEEQLLR----EEREKRRLQERERQYREEE 1054 Score = 50.1 bits (118), Expect = 4e-06 Identities = 56/219 (25%), Positives = 97/219 (44%), Gaps = 30/219 (13%) Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135 RR E R +E L + Q R + ++L + E + R+++QL+ Q +++ Sbjct: 1685 RRQERDRKFREEEQQLRR---QERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQ 1739 Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLS 195 L+R+E R +K EE +L+ + Q+ + + + K R +E LR+E RE QQ ++ E Sbjct: 1740 LRRQE--RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE--REEQQLRSQESDR 1795 Query: 196 KLNTESPDRSACQSAVCGPQSST----WKLPILPRDHSWARSWAYRD-SLKAEEN----- 245 K E R + PQ W+ L + R RD +AEE Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855 Query: 246 -----------RKLQKMKDEQHQKSELLELKRQQQEQER 273 + QK + E+ +K ++RQQ+E++R Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894 Score = 48.5 bits (114), Expect = 1e-05 Identities = 52/225 (23%), Positives = 94/225 (41%), Gaps = 35/225 (15%) Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRL--GGSQSETEVRQKQQLQLMQSKYK 133 R+ E QR E LE+ Q R + R L G QSE + R +Q+ + + + Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEF 193 + ++E R ++ AEE +LQ K + E+ E+ +R + R RE +Q + E Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL----- 248 ++ E + + W R+++ +E KL Sbjct: 234 QDRVFQEEEE----------------------------KEWRKRETVLRKEEEKLQEEEP 265 Query: 249 QKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293 Q+ ++ Q ++ +L +L+RQ+ +ER + Q + R L R Q Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310 Score = 45.8 bits (107), Expect = 7e-05 Identities = 44/213 (20%), Positives = 91/213 (42%), Gaps = 34/213 (15%) Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANLE-KWKEQNRAKPVHLVPRRLGGSQSETEV 119 Q R + + R+ ++ EQEL + E + K + +H R+ Q E ++ Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540 Query: 120 RQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR 179 R++++ Q + +K + EE +R +E E Q++ +R++ +LEE+K ++ R Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLR-----QEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595 Query: 180 EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDS 239 + + QQ + E +L E RD + Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQE-------------------------RDRKFRED---EQL 1627 Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQE 272 L+ E ++L + + ++ E +L+RQ++EQ+ Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660 Score = 44.7 bits (104), Expect = 2e-04 Identities = 46/222 (20%), Positives = 104/222 (46%), Gaps = 37/222 (16%) Query: 76 RRNEIQRIAEQELAN-------LEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLM 128 +++E+Q+ EQ L E+ ++ + + +L G + ET RQ+ + Q Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081 Query: 129 QSKYKQK----LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK--KRLQENLRREAF 182 + + Q+ L REE + +++ E + ++ + +Q+E+ L E+ KR ++ L R+ + Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ-Y 1140 Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKA 242 RE ++ + E +L E P++ R R + + L+ Sbjct: 1141 REEEEVQQEE--EQLLREEPEKR--------------------RRQELERQYREEEELQQ 1178 Query: 243 EENRKLQKMKDEQHQKSELLELKRQQ-QEQERAKIHQTEHRR 283 EE + L++ ++++ Q+ E + ++ Q Q+R + ++ E +R Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220 Score = 44.3 bits (103), Expect = 2e-04 Identities = 55/236 (23%), Positives = 104/236 (44%), Gaps = 30/236 (12%) Query: 61 QRRTSAYTLIAPNINRRNEIQRIAEQELANL-EKWKEQNRAKPVH----LVPRRLGGSQS 115 +R T + + E+Q+ EQ L EK + Q R + L + Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126 Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSN-KLEEKKRLQ 174 E E R++Q+L+ Q + ++++++EE +++E E+ Q+++ RE+ + EE++ L+ Sbjct: 1127 EREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 E + +QY+ E L + + R Q S K P + Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDE-------DQRSDLKWQWEPEKEN----- 1233 Query: 235 AYRDS---LKAEENRKLQKMKDEQ----HQKSELLELKRQQQEQERAKIHQTEHRR 283 A RD+ K EN + ++++D Q + +L L +QQE++R + E RR Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR----EQERRR 1285 Score = 42.7 bits (99), Expect = 6e-04 Identities = 61/278 (21%), Positives = 120/278 (43%), Gaps = 41/278 (14%) Query: 38 EDQREGL----EAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQR-----IAEQEL 88 EDQR L E + R++ V+ R + + + R + Q+ + EQ+ Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276 Query: 89 ANLE----KWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQ-LQLMQSKYKQKLKREESVR 143 + E +W++++R P R +++ R+ Q+ QL++ + ++K +R+E+ R Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336 Query: 144 IKKEAE----EAELQKMKAIQREKSNK-------------LEEKKRLQENLRREAF-REH 185 +E E E E Q ++ +R++ + LEE++RL+ R F +E Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396 Query: 186 QQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEEN 245 QQ + E +L + + + Q K + R R L+ E Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK--FREEEQQVRRQERERKFLEEE-- 1452 Query: 246 RKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 Q+++ E+H+K E ++ QE+E ++H+ E R Sbjct: 1453 ---QQLRQERHRK--FREEEQLLQEREEQQLHRQERDR 1485 Score = 42.4 bits (98), Expect = 8e-04 Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 34/215 (15%) Query: 79 EIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK--- 135 ++ R ++ E+ ++ + K + +L G + E RQ+++ + + + Q+ Sbjct: 942 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001 Query: 136 -LKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---KKRLQENLRREAFREHQQYKTA 191 L REE + +++ E + +K +Q+E+ L E K+RLQE R +RE ++ + Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE--RERQYREEEELQQE 1059 Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKM 251 E + G + T R R + + L+ EE + L++ Sbjct: 1060 E----------------EQLLGEERET------RRRQELERQYRKEEELQQEEEQLLREE 1097 Query: 252 KDE---QHQKSELLELKRQQQEQERAKIHQTEHRR 283 ++ Q ++ + E + QQE+E+ + E RR Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132 Score = 41.2 bits (95), Expect = 0.002 Identities = 51/256 (19%), Positives = 104/256 (40%), Gaps = 49/256 (19%) Query: 74 INRRNEIQRIAEQELANLEKWKE----------QNRAKPVHLVPRRLGGSQSETEVRQ-- 121 + R+ ++ E+EL + E+ ++ Q R + ++L + E ++RQ Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412 Query: 122 -----KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKL-EEKKRLQE 175 +++ QL + + +K + EE ++E E L++ + +++E+ K EE++ LQE Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472 Query: 176 NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWA 235 ++ R+ + K E +L + DR + + +S + L + R Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL---RSQEPERKFLEEEQQLHRQQR 1529 Query: 236 YRDSLKAE----------------------------ENRKLQKMKDEQHQKSELLELKRQ 267 R L+ E E + Q + E+ +K L E K + Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589 Query: 268 QQEQERAKIHQTEHRR 283 +QEQER + + R Sbjct: 1590 RQEQERKFMEDEQQLR 1605 Score = 39.7 bits (91), Expect = 0.005 Identities = 56/259 (21%), Positives = 108/259 (41%), Gaps = 46/259 (17%) Query: 36 PVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWK 95 P+ +QRE R+ Q+R + +R +R E+EL LE+ + Sbjct: 789 PLREQRE----------RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838 Query: 96 EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVR----IKKEAEEA 151 + R + + G Q + E R+ Q+ Q K++ +L+ E R K A + Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQE 897 Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL----SKLNTESPDRSAC 207 +L+K + + +E+ +L+ ++R E RR+ + +QY+ E L +L E ++ Sbjct: 898 QLRKEQQLLQEEEEELQREER--EKRRRQ--EQERQYREEEQLQQEEEQLLREEREKRRR 953 Query: 208 QSAVCGPQSSTWKLPILPRDHSWARSWAYR---DSLKAEENRKLQKMKDEQHQKSELLEL 264 Q R+ + + + + L EE K ++ + E+ + E Sbjct: 954 QE----------------RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE---- 993 Query: 265 KRQQQEQERAKIHQTEHRR 283 + QQE+E+ + E RR Sbjct: 994 EELQQEEEQLLREEREKRR 1012 Score = 37.7 bits (86), Expect = 0.019 Identities = 39/172 (22%), Positives = 77/172 (44%), Gaps = 10/172 (5%) Query: 31 QGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELAN 90 Q +L E R+ LE P RE Q R + + + E Q++ QE Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDR 1795 Query: 91 LEKWKEQNRAKPVHLVPRRLGGSQSETEVR-QKQQLQLMQSKYKQKLKREESVRIKK--- 146 + +EQ R + ++L Q + + R +++QLQL + + + + +R+ R ++ Sbjct: 1796 KFREEEQLRQEREE---QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852 Query: 147 --EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196 E E Q++ + +K + E+K +E++RR+ E + + E S+ Sbjct: 1853 TQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904 Score = 37.4 bits (85), Expect = 0.025 Identities = 51/265 (19%), Positives = 109/265 (41%), Gaps = 35/265 (13%) Query: 30 RQGELSPVEDQREGLEAAPKGPSR--------ESVVHAGQRRTSAYTLIAPNINRRNEIQ 81 R+ EL E++R + + R E G++R SA P + + E Q Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA----RPPLREQRERQ 797 Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141 AE+ +++ + K RR + E E++ ++ + +Q + + + +EE Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRR----EREKELQFLEEEEQLQRRERAQQLQEEE 853 Query: 142 VRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTES 201 ++++ E Q+ + Q+ + EE+KR + L + + Q K + L + E Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-EEEE 912 Query: 202 PDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE---QHQK 258 R + R R + + L+ EE + L++ +++ Q ++ Sbjct: 913 LQREEREKR---------------RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957 Query: 259 SELLELKRQQQEQERAKIHQTEHRR 283 + + K+ QQ++E+ + E RR Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRR 982 Score = 36.2 bits (82), Expect = 0.055 Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 32/220 (14%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK--- 133 R E Q++ QE +EQ + H R+ + + R++QQL + K Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERH---RKFREEEQLLQEREEQQLHRQERDRKFLE 1489 Query: 134 --QKLKREESVRIKKEAE-------------EAELQKM----KAIQREKSNKLEEKKRLQ 174 Q+L+R+E R +E E E +L + K +Q E+ + +E+ + + Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRS-ACQSAVCGPQSSTWKLPILPRDHSWARS 233 R FRE +Q + +L+ + DR + Q K D R Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK---FMEDEQQLRR 1606 Query: 234 WAYRDSLKAEENRKLQKMKDEQ-HQKSELLELKRQQQEQE 272 + L+ E +RK + +DEQ Q+ E +L RQ+++++ Sbjct: 1607 QEGQQQLRQERDRKFR--EDEQLLQEREEQQLHRQERDRK 1644 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 63.9 bits (154), Expect = 2e-10 Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%) Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 ++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E Sbjct: 788 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 839 Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193 E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 899 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253 L +L + + Q + P SSTW + + + K EE R+ Q ++ Sbjct: 900 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 957 Query: 254 EQHQKSELLELKRQQQEQERAKI 276 ++ Q+ EL++ +QQQ+Q++ K+ Sbjct: 958 QRRQQRELMKALQQQQQQQQQKL 980 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%) Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775 Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196 E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L + Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 835 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256 E + A + + +L + R + E R+ + M+ Q Sbjct: 836 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 895 Query: 257 QKSELLELKRQQQEQERAKI 276 Q+ L L++QQQ+Q+ A++ Sbjct: 896 QQEALRRLQQQQQQQQLAQM 915 Score = 28.9 bits (63), Expect = 8.8 Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%) Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152 A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++ Sbjct: 591 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 645 Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 Q+ A+ ++ L K R+ + N+ R T T S +V Sbjct: 646 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 703 Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270 P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E Sbjct: 704 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 761 Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293 R + + RR R Q Sbjct: 762 ILRRQQEEERKRREEEELARRKQ 784 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 63.9 bits (154), Expect = 2e-10 Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%) Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 ++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E Sbjct: 815 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 866 Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193 E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 926 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253 L +L + + Q + P SSTW + + + K EE R+ Q ++ Sbjct: 927 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 984 Query: 254 EQHQKSELLELKRQQQEQERAKI 276 ++ Q+ EL++ +QQQ+Q++ K+ Sbjct: 985 QRRQQRELMKALQQQQQQQQQKL 1007 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%) Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802 Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196 E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L + Sbjct: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 862 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256 E + A + + +L + R + E R+ + M+ Q Sbjct: 863 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 922 Query: 257 QKSELLELKRQQQEQERAKI 276 Q+ L L++QQQ+Q+ A++ Sbjct: 923 QQEALRRLQQQQQQQQLAQM 942 Score = 28.9 bits (63), Expect = 8.8 Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%) Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152 A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++ Sbjct: 618 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 672 Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 Q+ A+ ++ L K R+ + N+ R T T S +V Sbjct: 673 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 730 Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270 P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E Sbjct: 731 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 788 Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293 R + + RR R Q Sbjct: 789 ILRRQQEEERKRREEEELARRKQ 811 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 63.9 bits (154), Expect = 2e-10 Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%) Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 ++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845 Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193 E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253 L +L + + Q + P SSTW + + + K EE R+ Q ++ Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963 Query: 254 EQHQKSELLELKRQQQEQERAKI 276 ++ Q+ EL++ +QQQ+Q++ K+ Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%) Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781 Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196 E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L + Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256 E + A + + +L + R + E R+ + M+ Q Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901 Query: 257 QKSELLELKRQQQEQERAKI 276 Q+ L L++QQQ+Q+ A++ Sbjct: 902 QQEALRRLQQQQQQQQLAQM 921 Score = 28.9 bits (63), Expect = 8.8 Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%) Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152 A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++ Sbjct: 597 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 651 Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 Q+ A+ ++ L K R+ + N+ R T T S +V Sbjct: 652 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 709 Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270 P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E Sbjct: 710 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 767 Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293 R + + RR R Q Sbjct: 768 ILRRQQEEERKRREEEELARRKQ 790 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 63.9 bits (154), Expect = 2e-10 Identities = 53/203 (26%), Positives = 102/203 (50%), Gaps = 16/203 (7%) Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 ++R EQE+A L + +E+ + RRL + E E R+KQ+ L + + E Sbjct: 794 LRRQREQEIA-LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE-------E 845 Query: 140 ESVRIKKEAEEAE--LQKMKAIQREKSNKL----EEKKRLQENLRREAFREHQQYKTAEF 193 E+ + +E EEA+ L++ + E++ +L EE+KR + ++R+ Q+ + E Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 905 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253 L +L + + Q + P SSTW + + + K EE R+ Q ++ Sbjct: 906 LRRLQQQQQQQQLAQMKL--PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREE 963 Query: 254 EQHQKSELLELKRQQQEQERAKI 276 ++ Q+ EL++ +QQQ+Q++ K+ Sbjct: 964 QRRQQRELMKALQQQQQQQQQKL 986 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%) Query: 84 AEQELANLEKWK----EQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 A ++L LEK K EQ R + R + + E+R++Q+ L + + +++ +RE Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781 Query: 140 ESVRIKKEAEEA-ELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEFLSK 196 E +++ EEA Q+ + I + + EE+++ +E LRR E RE ++ + E L + Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQH 256 E + A + + +L + R + E R+ + M+ Q Sbjct: 842 KQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ 901 Query: 257 QKSELLELKRQQQEQERAKI 276 Q+ L L++QQQ+Q+ A++ Sbjct: 902 QQEALRRLQQQQQQQQLAQM 921 Score = 28.9 bits (63), Expect = 8.8 Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 18/203 (8%) Query: 100 AKPVH---LVPRRLGGSQSETEVRQKQQLQ----LMQSKYKQKLKREESVRIKKEAEEAE 152 A P H L RL Q T + Q Q LQ L+Q +Y Q L +++ K A ++ Sbjct: 597 APPPHMGELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQ-----KAALSSQ 651 Query: 153 LQKMKAIQREKSNKLEEKKRLQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 Q+ A+ ++ L K R+ + N+ R T T S +V Sbjct: 652 QQQQLALLLQQFQTL--KMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSV 709 Query: 212 CG-PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE 270 P +T P L + ++ A + + E K ++E+ ++ E EL+RQQ+E Sbjct: 710 WDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE--ELRRQQEE 767 Query: 271 QERAKIHQTEHRRVNNAFLDRLQ 293 R + + RR R Q Sbjct: 768 ILRRQQEEERKRREEEELARRKQ 790 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 61.6 bits (148), Expect = 1e-09 Identities = 61/239 (25%), Positives = 95/239 (39%), Gaps = 27/239 (11%) Query: 10 SGLGASPASRPTRDPQDPSGRQGELSPVEDQREGL----EAAPKGPSRESVVHAGQRRTS 65 S ASPA P P P+ Q E P E + AP P S AG Sbjct: 539 SAAPASPAPSPAPSPT-PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDRE 597 Query: 66 AYTLIAPNINRRNEIQRIAEQELANLE-----KWKEQNRAKPVHLVPRRLGGSQ--SETE 118 T + R+ QR E++ L+ + +E+ A+ R ++ E E Sbjct: 598 EATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQE 657 Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178 R+K Q + + + QK K E R ++EAE L++ K Q+++ + E +KRL+E ++ Sbjct: 658 AREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMK 717 Query: 179 REAFREHQQYKTAEFLSKLNT--ESPD-------------RSACQSAVCGPQSSTWKLP 222 R E + K + + N SP+ + A Q PQ W LP Sbjct: 718 RTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLP 776 Score = 36.6 bits (83), Expect = 0.042 Identities = 37/173 (21%), Positives = 79/173 (45%), Gaps = 18/173 (10%) Query: 23 DPQDPSGRQGEL-SPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNI------- 74 +P+ PSG+ G +P +++ EA +GP+ ++ R + +P Sbjct: 67 EPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP 126 Query: 75 NRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134 + E+++ E+ L K + + RAK +L ++ + E + + ++ QL + + Sbjct: 127 PTKQEVKKAGERH--KLAKERREERAK--YLAAKKAVWLEKEEKAKALREKQLQERR--- 179 Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQ 187 +R E R+K E A L++ + + EK NK + +Q ++++ QQ Sbjct: 180 --RRLEEQRLKAEQRRAALEERQRQKLEK-NKERYEAAIQRSVKKTWAEIRQQ 229 Score = 35.4 bits (80), Expect = 0.094 Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 14/159 (8%) Query: 161 REKSNKLEEKKRLQENLRREAFREHQQYKT-AEFLSKLNTESPDRSACQSAVCGPQSSTW 219 RE++ +L +KR Q +RE RE Q+ + AE ++ E R A A ++ Sbjct: 596 REEATRLLAEKRRQAREQRE--REEQERRLQAERDKRMREEQLAREAEARAEREAEARR- 652 Query: 220 KLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQT 279 R+ AR A + EE +LQK K+E +S E +RQ+ E+E+ Q Sbjct: 653 ------REEQEAREKAQAEQ---EEQERLQKQKEEAEARSRE-EAERQRLEREKHFQQQE 702 Query: 280 EHRRVNNAFLDRLQGKSQPGGLEQSGGCWNMNSGNSWGS 318 + R+ L+ + +++ + ++ + N+ GS Sbjct: 703 QERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGS 741 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 55.1 bits (131), Expect = 1e-07 Identities = 60/215 (27%), Positives = 95/215 (44%), Gaps = 26/215 (12%) Query: 79 EIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEV----RQKQQLQLMQSKY 132 E +R+ EQ L LE+ W+E R + L+ G + E R++QQ L + Sbjct: 244 EKRRLEEQRLQALERRLWEENRRQE---LLEEEGEGQEPPLEAERAPREEQQRSLEAPGW 300 Query: 133 KQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192 + +RE R + EAEE + Q E+ +LEE RL+E R +E ++ + AE Sbjct: 301 EDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRR----QEEEEGRCAE 356 Query: 193 FLSKLNTES----PDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL 248 L + E + ++ V GP P + R A + L EE Sbjct: 357 ELKRQEEEEAEGWEELEQQEAEVQGP-------PEALEETGEGRRGAEEEDLGEEEEEGQ 409 Query: 249 QKMKDEQHQKSELL-ELKRQQQEQERAKIH-QTEH 281 ++D + Q SELL + + + ++QER K Q EH Sbjct: 410 AHLEDWRGQLSELLNDFEERLEDQERLKPEGQREH 444 Score = 37.7 bits (86), Expect = 0.019 Identities = 45/189 (23%), Positives = 71/189 (37%), Gaps = 28/189 (14%) Query: 11 GLGASPASRPTRDPQDPSGRQGELSPVED-------QREGLEAAPKGPSRESVVHAGQRR 63 G G P R P++ R E ED +RE LEA + ++ A +RR Sbjct: 274 GEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERR 333 Query: 64 TSAYTLIAPNINRRNE-----IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETE 118 R+ E + + QE E W+E Q E E Sbjct: 334 RLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELE---------------QQEAE 378 Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178 V+ + L ++ ++ EE + ++E +A L+ + E N EE+ QE L+ Sbjct: 379 VQGPPEA-LEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLK 437 Query: 179 REAFREHQQ 187 E REH + Sbjct: 438 PEGQREHSE 446 Score = 34.3 bits (77), Expect = 0.21 Identities = 47/201 (23%), Positives = 76/201 (37%), Gaps = 41/201 (20%) Query: 17 ASRPTRDPQDPSGRQGELSPVEDQREGLEAAP---KGPSRESVVHAGQRRTSAYTLIAPN 73 A RP +P +PS E S D+R P KG R+ A +R+ ++ L A Sbjct: 993 AGRPDPEPSEPSKEDQESS---DRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQ 1049 Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 + ++ +E KP+ L GS+ +V Q L + + K Sbjct: 1050 QEKPSQTPEAGRKE-------------KPMLQSRHSLDGSKLTEKVETAQPLWITLALQK 1096 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQRE--------------------KSNKLEEKKRL 173 QK RE+ ++ + E ++ + + +E KS L E+KR Sbjct: 1097 QKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRP 1156 Query: 174 QENLRREAFREHQQYKTAEFL 194 + + R RE Q K A L Sbjct: 1157 ETAVSRLERRE--QLKKANTL 1175 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 7/118 (5%) Query: 76 RRNEI-QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQ 134 +R E+ QR+AE+ E+ + A+ +L E +R++++ + Q + Sbjct: 511 KREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQ--- 567 Query: 135 KLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAE 192 +EE R+++EAE ++ K QRE+ +LE KKRL+E ++R E KT++ Sbjct: 568 ---KEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSD 622 Score = 33.1 bits (74), Expect = 0.47 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 22/145 (15%) Query: 139 EESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLN 198 EE+ R+ L + + + RE+ K E ++R QE L R+ E Q E ++ Sbjct: 477 EEATRL--------LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRRE 528 Query: 199 TESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK 258 ES A Q+ ++ R R + EE + Q+ K+E+ + Sbjct: 529 EESRRLEAEQAR--------------EKEEQLQRQAEERALREREEAERAQRQKEEEARV 574 Query: 259 SELLELKRQQQEQERAKIHQTEHRR 283 E E RQ++E+ + Q R Sbjct: 575 REEAERVRQEREKHFQREEQERLER 599 Score = 32.7 bits (73), Expect = 0.61 Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 25/180 (13%) Query: 127 LMQSKYKQKLKREESVRIKKEAEEAELQKMKAI-----QREKSNKLEEKKRLQENLRREA 181 L + + + +RE+ R ++E EE E QK + + + + + EE +RL+ RE Sbjct: 483 LAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQARE- 541 Query: 182 FREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLK 241 +E Q + AE + E +R+ Q AR + ++ Sbjct: 542 -KEEQLQRQAEERALREREEAERAQRQK------------------EEEARVREEAERVR 582 Query: 242 AEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQPGGL 301 E + Q+ + E+ ++ + LE ++ + A +T +R + L G ++ L Sbjct: 583 QEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSAL 642 >gi|41152097 DNA segment on chromosome X and Y (unique) 155 expressed sequence isoform 1 [Homo sapiens] Length = 695 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/176 (22%), Positives = 92/176 (52%), Gaps = 5/176 (2%) Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 ++Q+LQ ++ + +++ +RE+ ++ AEE + ++++ ++RE+ K EEK R +E +R+ Sbjct: 274 ERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERER--KREEKLRKREQKQRD 331 Query: 181 AFREHQQYKTAEFLSKLNTESPDRSACQS-AVCGPQSSTWKLPILPRDHSWARSWAYRDS 239 Q K + ++ + ++ + + Q + + ++ S A++ R+ Sbjct: 332 RELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQ 391 Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295 + EE +LQ + E+ ++ + EL+R ++E+ERA Q + R + L L K Sbjct: 392 EQKEEKLRLQ--QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSK 445 Score = 40.0 bits (92), Expect = 0.004 Identities = 46/206 (22%), Positives = 98/206 (47%), Gaps = 38/206 (18%) Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIK------KEAEEAELQKMKAIQREKSNKLEEKKR 172 ++ L+ M+ YK + + + IK K +A ++K + ++R+K +LE+++ Sbjct: 228 IQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKK-RQLERQKLQELEQQR- 285 Query: 173 LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR 232 +E RRE +E ++ + AE + E +R + + K RD R Sbjct: 286 -EEQKRRE--KEAEERQRAEERKQKELEELERERKR------EEKLRKREQKQRDRELRR 336 Query: 233 SWAYRDSLKAEENRKLQ-KMKDEQHQ-------------------KSELLELKRQQQEQE 272 + + L+AEE ++LQ K+K E+ + +++ ++L+ Q+Q++E Sbjct: 337 NQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEE 396 Query: 273 RAKI-HQTEHRRVNNAFLDRLQGKSQ 297 + ++ Q E RR+ A L R++ + + Sbjct: 397 KLRLQQQEERRRLQEAELRRVEEEKE 422 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 52.8 bits (125), Expect = 6e-07 Identities = 49/208 (23%), Positives = 95/208 (45%), Gaps = 23/208 (11%) Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140 ++I EQE EK +EQ RR E E + ++Q ++M K ++K++R+E Sbjct: 321 EKIREQE----EKIREQEEKM------RRQEEMMWEKEEKMRRQEEMMWEK-EEKMRRQE 369 Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQYKTAEFL 194 + +KE + ++M + EK +LEEK R QE R+E + +Q K E Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429 Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDE 254 +K+ + + + + W+ ++ R+ K +E ++ + +++ Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREEEKRQEQEEMWRQEEK 484 Query: 255 QHQKSELLELKRQQQEQERAKIHQTEHR 282 H++ E+ K + EQE KI + E + Sbjct: 485 IHEQEEIWRQKEKMHEQEE-KIRKQEEK 511 Score = 52.0 bits (123), Expect = 1e-06 Identities = 54/260 (20%), Positives = 107/260 (41%), Gaps = 21/260 (8%) Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96 + +Q + E K E + +R+ + R + ++I EQE + W++ Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 456 Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQK 155 + + + + E RQ++++ + ++QK K E+ +I+K+ E+ Q+ Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516 Query: 156 MKAI--------QREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSAC 207 K Q EK + EEK R QE + RE + H+Q K E + E D+ Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEKRQEQEDKMWR 574 Query: 208 Q-SAVCGPQSSTWKLPILPRDHSWARS------WAYRDSLKAEENRKLQKMKDEQHQKSE 260 Q + + W+ R+ R W + ++ +E + ++ + + Q+ + Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634 Query: 261 LLELKRQQQEQERAKIHQTE 280 + E + QEQE Q E Sbjct: 635 IREQEEMTQEQEEKMGEQEE 654 Score = 43.1 bits (100), Expect = 5e-04 Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 22/208 (10%) Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYKQKLKRE 139 ++I EQE E W+E+ + + + E ++ RQ+++++ + K ++E Sbjct: 538 EKIREQE----EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV---WRQE 590 Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFRE--HQQYKTAEFLSKL 197 E +R ++E + + +KM Q EK + EEK + QE RE + Q+ T E K+ Sbjct: 591 EKIREQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649 Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257 + + + + + W R R + + E+ R+ ++M EQ + Sbjct: 650 GEQEEKMCEQEEKMQEQEETMW------RQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703 Query: 258 K-----SELLELKRQQQEQERAKIHQTE 280 K ++ E + + QEQE Q E Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRRQEE 731 Score = 41.2 bits (95), Expect = 0.002 Identities = 50/232 (21%), Positives = 110/232 (47%), Gaps = 39/232 (16%) Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123 + ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ + Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293 Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183 L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E + Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347 Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAE 243 E + + E + E ++ Q + W+ ++ R ++ + E Sbjct: 348 EEKMRRQEEMM----WEKEEKMRRQ------EEMMWE-----KEEKMRR----QEEMMWE 388 Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295 + K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 438 Score = 35.0 bits (79), Expect = 0.12 Identities = 39/198 (19%), Positives = 90/198 (45%), Gaps = 34/198 (17%) Query: 81 QRIAEQELANLEK-WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 ++I EQE EK W+++ + + + + E + ++Q + +Q + ++ ++E Sbjct: 577 EKIREQE----EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632 Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENL--RREAFREHQQYKTAEFLSKL 197 E +R ++E + + +KM Q EK + EEK + QE R+E Q+ K E K+ Sbjct: 633 EKIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691 Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257 + + + + W+ ++ E+ K+Q+ +++ + Sbjct: 692 REQ-------EEMMQEQEEKMWE----------------QEEKMCEQEEKMQEQEEKMRR 728 Query: 258 KSELL---ELKRQQQEQE 272 + E + E++ +QQE++ Sbjct: 729 QEEKMWEQEVRLRQQEEK 746 Score = 33.9 bits (76), Expect = 0.27 Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%) Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174 T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 + +A +H + +KL + + + W+ + W Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 316 Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282 ++ E+ K+++ +++ ++ E++ K ++ ++ + + E + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 51.2 bits (121), Expect = 2e-06 Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 19/224 (8%) Query: 80 IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 +++ +E+++A L+K E+ A+ + ++L + E + + K L+ QS+Y K+ +E Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY-LKISQE 528 Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNT 199 + + EE ELQK KAI E NKL + ++ E R + + L + Sbjct: 529 KEQQESLALEELELQK-KAILTESENKLRDLQQEAETYRTRILELESSLEKS--LQENKN 585 Query: 200 ESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEEN----RKLQKMKDEQ 255 +S D + A + ++ ++ H +SLK +++ KLQ +K + Sbjct: 586 QSKDLAVHLEAEKNKHNK--EITVMVEKHK-----TELESLKHQQDALWTEKLQVLKQQY 638 Query: 256 HQKSELLELKRQQQEQERAK----IHQTEHRRVNNAFLDRLQGK 295 + E L K +Q+++ K I Q +N L++L K Sbjct: 639 QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682 Score = 45.4 bits (106), Expect = 9e-05 Identities = 65/286 (22%), Positives = 129/286 (45%), Gaps = 39/286 (13%) Query: 31 QGELSPVEDQREGLEAAPKGPSR---ESVVHAGQRRTSAYTL--IAPNINRRNEIQ-RIA 84 + + S +E + LE K + E H Q+ +L + N N++ +I+ + Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562 Query: 85 EQELANLEKWKEQ--NRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESV 142 Q+L + ++ E+ NR K E + + Q+ M+++ + K K E V Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAE-----------EKILTLENQVYSMKAELETKKKELEHV 1611 Query: 143 RIKKEAEEAELQKMK-AIQREKSNKLEEKKR--------LQENLRREAFREHQQYK--TA 191 + +++E EL+ ++ ++ E + KL E KR +++ L + + +QYK T Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE 1671 Query: 192 EFLSKLNTESPDRS----ACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247 LS+LNT+ +R + + +SS + I+PR S AY + +A+ Sbjct: 1672 SHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR--SAKNVAAYTEQEEADSQGC 1729 Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293 +QK +E K +L+ ++E+ ++ Q + V++ F R Q Sbjct: 1730 VQKTYEE---KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQ 1772 Score = 43.1 bits (100), Expect = 5e-04 Identities = 45/215 (20%), Positives = 94/215 (43%), Gaps = 28/215 (13%) Query: 82 RIAEQELA---NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKR 138 RI E E + +L++ K Q++ VHL + ++ T + +K + +L K++Q Sbjct: 568 RILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALW 627 Query: 139 EESVRIKKEAEEAELQKMKA-IQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197 E +++ K+ + E++K++ ++EK L++K+ + F+ H + + L KL Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--------FQAHIEEMNEKTLEKL 679 Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257 + + + + S + + KL + L +++ KMK E Sbjct: 680 DVKQTELESLSSELSEVLKARHKL---------------EEELSVLKDQT-DKMKQELEA 723 Query: 258 KSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRL 292 K + + QQQ K H+ +R A D++ Sbjct: 724 KMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI 758 Score = 36.6 bits (83), Expect = 0.042 Identities = 45/219 (20%), Positives = 102/219 (46%), Gaps = 31/219 (14%) Query: 68 TLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGG---SQSETEVRQKQQ 124 TL +++ ++++ E L + ++Q AK + + G + S E QK+Q Sbjct: 969 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQ 1028 Query: 125 LQLMQSKYKQKLKREESVRIKKEAEEA-ELQKMKAIQ-REKSNKLEEKKRL-------QE 175 ++ + ++++L S+ KK ++A ELQ++ IQ +EK ++ E K+ +E Sbjct: 1029 IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1088 Query: 176 NLRRE-AFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 + +E + + + K L++L + +SA +++ ++ + Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET---------------KLK 1133 Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQER 273 A+ + L+ + N+ L K+ + +L+ELK +E +R Sbjct: 1134 AHLEKLEVDLNKSL---KENTFLQEQLVELKMLAEEDKR 1169 Score = 35.0 bits (79), Expect = 0.12 Identities = 50/262 (19%), Positives = 107/262 (40%), Gaps = 53/262 (20%) Query: 34 LSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEK 93 LS +E Q LE G RE Q+ + ++ +++ +QEL L+K Sbjct: 1918 LSNMEAQHNDLEFKLAGAEREK-----QKLGKEIVRLQKDLRM---LRKEHQQELEILKK 1969 Query: 94 WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES---VRIKK---E 147 +Q R + ++ Q + E++ L+ + ++ +L ++E + IK+ + Sbjct: 1970 EYDQEREE-------KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINK 2022 Query: 148 AEEAELQKMKAIQREKSNKLEEKKRLQENLRREA--FREHQQYKTAEFLSKLNTESPDRS 205 A+E E + +++ Q E + L++ ++L+R A + E + E +K+ Sbjct: 2023 AQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLE 2082 Query: 206 ACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR-----KLQKMKDEQHQKSE 260 Q Y+ L+ EEN + +++ + QK+ Sbjct: 2083 ELQK-------------------------KYQQKLEQEENPGNDNVTIMELQTQLAQKTT 2117 Query: 261 LLELKRQQQEQERAKIHQTEHR 282 L+ + ++++ R +IH E R Sbjct: 2118 LISDSKLKEQEFREQIHNLEDR 2139 Score = 29.3 bits (64), Expect = 6.8 Identities = 52/235 (22%), Positives = 102/235 (43%), Gaps = 38/235 (16%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQL-MQSKYKQK 135 R+ I+++ Q L + KE++ + + L +Q E R+K + ++ Q K +K Sbjct: 388 RSRIKQMTTQG-EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446 Query: 136 LKREESVRI---------------KKEAEE--AELQKM--KAIQREKSNKLEEKKRLQEN 176 EE + + KK +EE A+LQK+ K + R K +L +K + +E Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 505 Query: 177 LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR---- 232 +E + + +E+L K++ E Q ++ + K IL + R Sbjct: 506 EFQEQMKVALEKSQSEYL-KISQEKEQ----QESLALEELELQKKAILTESENKLRDLQQ 560 Query: 233 -SWAYRD---SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQE---RAKIHQTE 280 + YR L++ + LQ+ K++ + LE ++ + +E + H+TE Sbjct: 561 EAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE 615 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 50.8 bits (120), Expect = 2e-06 Identities = 42/208 (20%), Positives = 99/208 (47%), Gaps = 16/208 (7%) Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 +N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K + Sbjct: 294 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 348 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187 +K++R+E + +KE + L++M + EK +LEEK R QE R+E + +Q Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408 Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247 K E +K+ + + + + W+ ++ R+ K +E + Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREEEKRQEQEE 463 Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAK 275 + + +++ ++ E+ K + EQE+ + Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIR 491 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/259 (16%), Positives = 104/259 (40%), Gaps = 18/259 (6%) Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96 + +Q + E K E + +R+ + R + ++I EQE + W++ Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK---KMWRQ 442 Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKM 156 + + + + E RQ+++++ + ++QK K E +I+K+ E+ Q+ Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502 Query: 157 KAIQREKSNKLEEKK--RLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGP 214 K +E+ + +E+K R +E +R + + +Q + ++ E ++ Q Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562 Query: 215 QSSTWKLPILPRD-------------HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSEL 261 Q + R+ + W + ++ +E ++ + Q+ ++ Sbjct: 563 QEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKM 622 Query: 262 LELKRQQQEQERAKIHQTE 280 E + + QEQE Q E Sbjct: 623 CEQEEKMQEQEEKMRRQEE 641 Score = 43.5 bits (101), Expect = 3e-04 Identities = 39/215 (18%), Positives = 102/215 (47%), Gaps = 30/215 (13%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQK 135 + E R E+++ EK +EQ + Q E ++R++++ Q ++K ++Q+ Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKR------------QEEEKIREQEKRQEQEAKMWRQE 422 Query: 136 LK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194 K RE+ +I+++ ++ Q+ K ++EK + EEK++ QE + R+ + +Q + Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWRQK 481 Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA------RSWAYRDSLKAEENRKL 248 K++ + R + W+ D + W + ++ E+ K+ Sbjct: 482 EKMHEQEKIRKQ--------EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR-EQEEKI 532 Query: 249 QKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 ++ +++ ++ E+++ + ++ ++ K+ + E R Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567 Score = 41.6 bits (96), Expect = 0.001 Identities = 46/208 (22%), Positives = 90/208 (43%), Gaps = 12/208 (5%) Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQK 135 R+ E R E+ EK EQ + + R + E + ++Q + M + ++ Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525 Query: 136 LKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRR--EAFREHQQYKTAEF 193 ++EE +R ++E + E ++M Q EK + EEK + QE +RR E RE Q+ K E Sbjct: 526 REQEEKIR-EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE-QEEKIREQ 583 Query: 194 LSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKD 253 K+ E ++ Q Q + + W + + +E + ++ + Sbjct: 584 KEKIR-EQEEKIWEQEEKIREQEEMMQ-------EQEEKMWEQEEKMCEQEEKMQEQEEK 635 Query: 254 EQHQKSELLELKRQQQEQERAKIHQTEH 281 + Q+ ++ E + + ++QE EH Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQEH 663 Score = 37.4 bits (85), Expect = 0.025 Identities = 48/234 (20%), Positives = 102/234 (43%), Gaps = 57/234 (24%) Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123 + ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ + Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 293 Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183 L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E + Sbjct: 294 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 347 Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYR--DSLK 241 E + + E + W + R + + Sbjct: 348 EEKMRRQEEMM-----------------------------------WEKEEKMRRLEEMM 372 Query: 242 AEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295 E+ K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 424 Score = 35.4 bits (80), Expect = 0.094 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 19/134 (14%) Query: 77 RNEIQRIAEQE---LANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 R + ++I EQE EK EQ RR E E + ++Q + ++ + + Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592 Query: 134 QKLKREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NL 177 + ++EE +R ++E + + +KM Q EK + EEK R QE Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652 Query: 178 RREAFREHQQYKTA 191 + E +EHQ++ A Sbjct: 653 QEEKMQEHQEHLEA 666 Score = 33.9 bits (76), Expect = 0.27 Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%) Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174 T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 258 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 + +A +H + +KL + + + W+ + W Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 316 Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282 ++ E+ K+++ +++ ++ E++ K ++ ++ + + E + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 50.4 bits (119), Expect = 3e-06 Identities = 58/236 (24%), Positives = 107/236 (45%), Gaps = 38/236 (16%) Query: 76 RRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGS------QSETEVRQKQQLQLMQ 129 ++ E++ I A +E+ E+ R + + +++ + Q E E +Q+LQL + Sbjct: 909 KKQELEEICHDLEARVEE--EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEK 966 Query: 130 SKYKQKLKREESVRIKKEAEEAELQKMKAI--------------QREKSNKLEEKKR--- 172 + KLK+ E +I E + +L K K + + EKS L + K Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026 Query: 173 -----LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRD 227 L+E LRRE E Q+ + + KL +S D S Q A Q + K+ + ++ Sbjct: 1027 AMITDLEERLRRE---EKQRQELEKTRRKLEGDSTDLSD-QIAELQAQIAELKMQLAKKE 1082 Query: 228 HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 + A + A++N L+K+++ + Q SEL ++ E ERA ++ E ++ Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISEL----QEDLESERASRNKAEKQK 1134 Score = 37.0 bits (84), Expect = 0.032 Identities = 42/213 (19%), Positives = 97/213 (45%), Gaps = 28/213 (13%) Query: 79 EIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYKQKLK 137 E Q AE L +E + Q A+ + L + Q+ETE+ + ++L+ + KQ+L+ Sbjct: 859 EKQLAAENRLTEMETLQSQLMAEKLQLQEQL----QAETELCAEAEELRARLTAKKQELE 914 Query: 138 R---EESVRIKKEAE-----EAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYK 189 + R+++E E +AE +KM+ +E +LEE++ ++ L+ E + K Sbjct: 915 EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK 974 Query: 190 TAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQ 249 E + + + A + + + + + + + E+++ L Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE---------------EKSKSLA 1019 Query: 250 KMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282 K+K++ LE + +++E++R ++ +T + Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQRQELEKTRRK 1052 Score = 33.1 bits (74), Expect = 0.47 Identities = 48/217 (22%), Positives = 93/217 (42%), Gaps = 37/217 (17%) Query: 84 AEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKR----- 138 A+QEL + R + V+++ + L E + Q+Q M+ K+ Q ++ Sbjct: 1157 AQQELRS-------KREQEVNILKKTL----EEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205 Query: 139 EESVRIKKEAEEAE----------LQKMKAIQREKSNKLEEKKRLQENLR--REAFREHQ 186 E++ R+K E+A+ ++K + + K + ++K+++ L+ + F E + Sbjct: 1206 EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265 Query: 187 QYKT--AEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAY-RDSLKAE 243 + +T A+ ++KL E + + S S K L +D S S L E Sbjct: 1266 RVRTELADKVTKLQVELDNVTGLLS------QSDSKSSKLTKDFSALESQLQDTQELLQE 1319 Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280 ENR+ + + Q + R+Q E+E H E Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE 1356 Score = 32.3 bits (72), Expect = 0.80 Identities = 48/253 (18%), Positives = 102/253 (40%), Gaps = 49/253 (19%) Query: 78 NEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLK 137 +E+Q E E A+ K ++Q R LG + + L ++ + + K Sbjct: 1114 SELQEDLESERASRNKAEKQKRD---------LGEELEALKTELEDTLDSTAAQQELRSK 1164 Query: 138 REESVRIKKEA-------EEAELQKMKAIQ----REKSNKLEEKKRLQENLRR------- 179 RE+ V I K+ EA++Q+M+ E + +LE+ KR++ NL + Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224 Query: 180 ---------------EAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPIL 224 + EH++ K L +L + + ++ + KL + Sbjct: 1225 ERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA---DKVTKLQVE 1281 Query: 225 PRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRV 284 + + S + DS ++ + ++ + ELL+ + +Q+ K+ Q E + Sbjct: 1282 LDNVTGLLSQS--DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK- 1338 Query: 285 NNAFLDRLQGKSQ 297 N+F ++L+ + + Sbjct: 1339 -NSFREQLEEEEE 1350 Score = 31.6 bits (70), Expect = 1.4 Identities = 36/161 (22%), Positives = 68/161 (42%), Gaps = 42/161 (26%) Query: 30 RQGELSPVEDQRE--------GLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81 R G L+ +E++R+ G +A +G Q++ +A ++ N Sbjct: 764 RAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNC------- 816 Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREES 141 A +L N + W+ + KP+ LQ+ + + + K EE Sbjct: 817 -AAYLKLRNWQWWRLFTKVKPL---------------------LQVSRQEEEMMAKEEEL 854 Query: 142 VRIKKE--AEEAELQKMKAIQREKSNKLEEKKRLQENLRRE 180 V+++++ A E L +M+ +Q S + EK +LQE L+ E Sbjct: 855 VKVREKQLAAENRLTEMETLQ---SQLMAEKLQLQEQLQAE 892 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 50.4 bits (119), Expect = 3e-06 Identities = 43/223 (19%), Positives = 102/223 (45%), Gaps = 19/223 (8%) Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 +N++ E + ++E +++W+E+ + + + R E E + ++Q ++M K + Sbjct: 355 LNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEK-E 409 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK------RLQENLRREAFREHQQ 187 +K++R+E + +KE + ++M + EK +LEEK R QE R+E + +Q Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469 Query: 188 YKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKL--------PILPRDHSWARSWAYRDS 239 K E +K+ + + + + W+ I + + +R Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529 Query: 240 LKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282 K E ++ + K++ H++ E + + ++ ++ K+H E + Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572 Score = 41.6 bits (96), Expect = 0.001 Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 42/229 (18%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQK 135 + E R E+++ EK +EQ + Q E ++R++++ Q ++K ++Q+ Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKR------------QEEEKIREQEKRQEQEAKMWRQE 483 Query: 136 LK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194 K RE+ +I+++ E+ Q+ K ++EK + EEK++ QE + R+ + +Q + Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWRQK 542 Query: 195 SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA------RSWAYRDSLKAEEN--- 245 K++ + + + + W+ D + W + ++ +E Sbjct: 543 EKIHEQ-------EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595 Query: 246 ------RKLQKMKDEQHQK-----SELLELKRQQQEQERAKIHQTEHRR 283 R+ ++M EQ +K ++ E + + QEQE Q E R Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644 Score = 40.8 bits (94), Expect = 0.002 Identities = 57/268 (21%), Positives = 110/268 (41%), Gaps = 20/268 (7%) Query: 22 RDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQ 81 R+ ++ Q ++ E++R+ E + R+ R+ I + E Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500 Query: 82 RIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEV-RQKQQLQLMQSKYK---QKLK 137 E+++ EK +E+ + + + R+ + + E+ RQK+++ + K + +K+ Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560 Query: 138 REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKL 197 R+E +E + E ++ Q EK + EEK R QE RE Q+ T E K+ Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE-----QEEMTQEQEEKM 615 Query: 198 NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQ 257 E ++ Q Q + R R + + E+ R+ ++M EQ + Sbjct: 616 G-EQEEKMCEQEEKMQEQEEKMR-----RQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669 Query: 258 K-----SELLELKRQQQEQERAKIHQTE 280 K ++ E + + QEQE Q E Sbjct: 670 KMWEQEEKMCEQEEKMQEQEEKMRRQEE 697 Score = 37.7 bits (86), Expect = 0.019 Identities = 48/232 (20%), Positives = 105/232 (45%), Gaps = 53/232 (22%) Query: 75 NRRNEIQRIAEQELANLEKWK-----EQNRAKPVHL------VPRRLGGSQSETEVRQKQ 123 + ++EIQ ++ LE+ K +Q +A+ HL V +L E E+ + Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR- 354 Query: 124 QLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFR 183 L Q + ++ ++EE ++ +E + + +K++ Q EK + EEK R QE + E + Sbjct: 355 ---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIREQEEKMRRQEEMMWE--K 408 Query: 184 EHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAE 243 E + + E + W+ ++ R ++ + E Sbjct: 409 EEKMRRQEEMM------------------------WE-----KEEKMRR----QEEMMWE 435 Query: 244 ENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295 + K+++++++ H++ ++ E + ++QE+E KI + E R+ A + R + K Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEK 485 Score = 36.6 bits (83), Expect = 0.042 Identities = 36/170 (21%), Positives = 77/170 (45%), Gaps = 28/170 (16%) Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRL 173 Q E RQ+++++ + K +++ EE +R ++E + + +KM Q EK + EEK + Sbjct: 576 QEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQE 631 Query: 174 QENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARS 233 QE R Q+ K E K+ + + + + W+ Sbjct: 632 QEEKMR-----RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE------------- 673 Query: 234 WAYRDSLKAEENRKLQKMKDEQHQKSELL--ELKRQQQEQERAKIHQTEH 281 ++ E+ K+Q+ +++ ++ E + + R +Q++E+ + HQ EH Sbjct: 674 ---QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ-EH 719 Score = 35.4 bits (80), Expect = 0.094 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 19/131 (14%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136 R + ++I EQE E+ ++ + Q E RQ+++++ + K +++ Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ- 653 Query: 137 KREESVRIKKEAEEAELQKM------KAIQREKSNKLEEKKRLQE----------NLRRE 180 EE +R ++E + + +KM Q EK + EEK R QE + E Sbjct: 654 --EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711 Query: 181 AFREHQQYKTA 191 +EHQ++ A Sbjct: 712 KMQEHQEHLEA 722 Score = 34.3 bits (77), Expect = 0.21 Identities = 40/176 (22%), Positives = 73/176 (41%), Gaps = 43/176 (24%) Query: 109 RLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLE 168 RL Q E RQ++++Q + K +++ EE +R ++E + +KM+ Q E + E Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEKMRR-QEEMMWEKE 409 Query: 169 EKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDH 228 EK R QE + E +E + + E + Sbjct: 410 EKMRRQEEMMWE--KEEKMRRQEEMM---------------------------------- 433 Query: 229 SWARSWAYRD-SLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 W + R+ K E K+++ ++E+ Q+ E + + ++QEQE Q E R Sbjct: 434 -WEKEEKIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487 Score = 33.9 bits (76), Expect = 0.27 Identities = 24/168 (14%), Positives = 73/168 (43%), Gaps = 4/168 (2%) Query: 117 TEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE--EAELQKMKAIQREKSNKLEEKKRLQ 174 T+ R L+L ++ + +E++ +++++ + E+E +++ +E KLE K L Sbjct: 260 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 319 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 + +A +H + +KL + + + W+ + W Sbjct: 320 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKI 377 Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHR 282 ++ E+ K+++ +++ ++ E++ K ++ ++ + + E + Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 50.4 bits (119), Expect = 3e-06 Identities = 51/247 (20%), Positives = 109/247 (44%), Gaps = 29/247 (11%) Query: 34 LSPVEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEK 93 + P E +R+ LE + E + L + R ++++ Q +E+ Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQ 586 Query: 94 WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAEL 153 KE+ + + + ++ +TE ++++L ++K K K+ E V +++ EE E Sbjct: 587 MKEEKKKQ----IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-EA 641 Query: 154 QKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCG 213 ++++ +Q+E EE++R QE L+++ E ++ + A +L + Q Sbjct: 642 RRLRWLQQE-----EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE---- 692 Query: 214 PQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQER 273 R R R+ + E+ R+L + E+ ++ E L+ +R+ QE+E+ Sbjct: 693 ------------RREQERREQERREQERREQERQLAEQ--ERRREQERLQAERELQEREK 738 Query: 274 AKIHQTE 280 A Q E Sbjct: 739 ALRLQKE 745 Score = 42.4 bits (98), Expect = 8e-04 Identities = 65/301 (21%), Positives = 123/301 (40%), Gaps = 34/301 (11%) Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61 + NS PA+ P+ PS Q E DQ +G P+ R ++V + Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462 Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121 + + P ++ A + + L + + + + P S ++ +++ Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522 Query: 122 KQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------KKR 172 L+ M K K++ +R E++R K+EAE+ QK ++ +K +LEE +K Sbjct: 523 NTPLR-MDPKEKER-QRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLRKV 577 Query: 173 LQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSA---VCGPQSSTWKLPILP 225 LQ R E +E + + K A+ K +R A + A + + Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637 Query: 226 RDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTEHR 282 + + W ++ + LQK K+E+ ++ + E KR +Q+EQER + + E Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697 Query: 283 R 283 R Sbjct: 698 R 698 Score = 40.0 bits (92), Expect = 0.004 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%) Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 + + E +R+AEQ +EQ R + R + E E R++Q+ QL + + Sbjct: 671 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 719 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190 +R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K Sbjct: 720 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 776 Query: 191 AE 192 E Sbjct: 777 KE 778 Score = 38.9 bits (89), Expect = 0.009 Identities = 25/115 (21%), Positives = 60/115 (52%), Gaps = 5/115 (4%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136 + E + QEL +K +EQ R + R + E +++++ + + + +++ Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707 Query: 137 KREESVRIKKEAEEAELQKMKA----IQREKSNKLEEKKRLQENLRREAFREHQQ 187 +RE+ ++ ++ E ++++A +REK+ +L +K++LQ L + +E QQ Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQ 761 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 49.3 bits (116), Expect = 6e-06 Identities = 47/231 (20%), Positives = 106/231 (45%), Gaps = 40/231 (17%) Query: 24 PQDPSGRQGELSPVE----DQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNE 79 PQ P G QG L P + Q+ P+GP R+ ++ T + L +P + ++ + Sbjct: 3792 PQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM------TQSRVLSSPQLAQQGQ 3845 Query: 80 IQR-----IAEQELANLEKWKEQNRAKPVHLVPRRLGGS----------------QSETE 118 A+Q+ + ++ + A HL + S Q + + Sbjct: 3846 GLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQ 3905 Query: 119 VRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLR 178 ++Q+QQLQ Q +Q+L++++ ++ ++ ++ + Q+++ Q+++ + +++ + Q+ + Sbjct: 3906 LQQQQQLQQQQ---QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962 Query: 179 REAFREHQQYKTAEFLSKLNT-ESPDRSACQSAVCGPQSSTWKLPILPRDH 228 ++ F++ QQ + L++ T SP + Q GP +P P H Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP-----GMPAKPLQH 4008 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 49.3 bits (116), Expect = 6e-06 Identities = 51/244 (20%), Positives = 108/244 (44%), Gaps = 29/244 (11%) Query: 37 VEDQREGLEAAPKGPSRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKE 96 VE +R+ LE + E + L + R ++++ Q +E+ KE Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL-QARERVEQMKE 593 Query: 97 QNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKM 156 + + + + ++ +TE ++++L ++K K K+ E V +++ EE E +++ Sbjct: 594 EKKKQ----IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE-EARRL 648 Query: 157 KAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQS 216 + +Q+E EE++R QE L+++ E ++ + A +L + Q Sbjct: 649 RWLQQE-----EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE------- 696 Query: 217 STWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 276 R R R+ + E+ R+L + E+ ++ E L+ +R+ QE+E+A Sbjct: 697 ---------RREQERREQERREQERREQERQLAEQ--ERRREQERLQAERELQEREKALR 745 Query: 277 HQTE 280 Q E Sbjct: 746 LQKE 749 Score = 40.0 bits (92), Expect = 0.004 Identities = 63/303 (20%), Positives = 123/303 (40%), Gaps = 34/303 (11%) Query: 7 VVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSR-----ESVVHAGQ 61 + NS PA+ P+ PS Q E DQ +G P+ R ++V + Sbjct: 408 IANSTPNPKPAAS---SPETPSAGQQEAKT--DQADGPREPPQSARRKRSYKQAVSELDE 462 Query: 62 RRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQ 121 + + P ++ A + + L + + + + P S ++ +++ Sbjct: 463 EQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKR 522 Query: 122 KQQLQLMQ--SKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEE---------K 170 L++ S +++ +R E++R K+EAE+ QK ++ +K +LEE + Sbjct: 523 NTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERLR 579 Query: 171 KRLQENLRREAFREHQ----QYKTAEFLSKLNTESPDRSACQSA---VCGPQSSTWKLPI 223 K LQ R E +E + + K A+ K +R A + A + + Sbjct: 580 KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR 639 Query: 224 LPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQK-SELLELKR--QQQEQERAKIHQTE 280 + + W ++ + LQK K+E+ ++ + E KR +Q+EQER + + E Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699 Query: 281 HRR 283 R Sbjct: 700 QER 702 Score = 40.0 bits (92), Expect = 0.004 Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 17/122 (13%) Query: 74 INRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 + + E +R+AEQ +EQ R + R + E E R++Q+ QL + + Sbjct: 675 LRKAAEAKRLAEQ--------REQERREQERREQERREQERREQE-RREQERQLAEQE-- 723 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREK-SNKLEEKKRL--QENLRREAFREHQQYKT 190 +R E R++ E E E +K +Q+E+ +LEEKK+ Q+ L +E Q+ K Sbjct: 724 ---RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA 780 Query: 191 AE 192 E Sbjct: 781 KE 782 Score = 38.9 bits (89), Expect = 0.009 Identities = 25/115 (21%), Positives = 60/115 (52%), Gaps = 5/115 (4%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136 + E + QEL +K +EQ R + R + E +++++ + + + +++ Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711 Query: 137 KREESVRIKKEAEEAELQKMKA----IQREKSNKLEEKKRLQENLRREAFREHQQ 187 +RE+ ++ ++ E ++++A +REK+ +L +K++LQ L + +E QQ Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRL-QKEQLQRELEEKKKKEEQQ 765 >gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] Length = 1317 Score = 48.5 bits (114), Expect = 1e-05 Identities = 50/190 (26%), Positives = 96/190 (50%), Gaps = 18/190 (9%) Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKA---IQREKSNKLEEKKR 172 E E +Q+++L+ ++SK K + EE K+++++AEL++M+ QR+++ ++ + R Sbjct: 597 EFERQQREELEKLESKRKLIEEMEE----KQKSDKAELERMQQEVETQRKETEIVQLQIR 652 Query: 173 LQE-NLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA 231 QE +L+R +F H + K + L++ +R Q + + + L Sbjct: 653 KQEESLKRRSF--HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQ 710 Query: 232 RSWAYRDSLKAE------ENRKLQKMKDEQHQKSELLELKRQQQEQERAKI--HQTEHRR 283 R ++ KAE E +LQK KDEQ+ K EL + + ++QE+E+ + H E R Sbjct: 711 RLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLR 770 Query: 284 VNNAFLDRLQ 293 + L+ Sbjct: 771 EKQEMIQLLR 780 >gi|81295809 pericentrin [Homo sapiens] Length = 3336 Score = 48.1 bits (113), Expect = 1e-05 Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 35/216 (16%) Query: 89 ANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEA 148 ANL+K KE + ++ R + + RQ+ +L+L++ +Q + +E V ++ Sbjct: 267 ANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLR---EQHAREKEEVVLRCGQ 323 Query: 149 EEAELQKMKAIQREKSNKL---------EEKKRLQENLRREAFREHQ----------QYK 189 E AEL++ + EK+ ++ EK ENLR+E +HQ Q + Sbjct: 324 EAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKE 383 Query: 190 TAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQ 249 AE ++L D++ + A+ +S H A R+ L++E R L+ Sbjct: 384 LAEQRAELEKIFQDKNQAERALRNLES-----------HHQAAIEKLREDLQSEHGRCLE 432 Query: 250 --KMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 + K ++ +K + LEL+ Q E K E R Sbjct: 433 DLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIR 468 Score = 38.9 bits (89), Expect = 0.009 Identities = 51/205 (24%), Positives = 95/205 (46%), Gaps = 24/205 (11%) Query: 85 EQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRI 144 +QE+ LE Q AKP PR + + EV +L+Q K ++KL + I Sbjct: 1496 QQEIQRLEGQLRQ-AAKPQPWGPRDSQQAPLDGEV------ELLQQKLREKLDEFNELAI 1548 Query: 145 KKEA-------EEAELQKMKAIQ---REKSNKLEEKKRLQENLRREAFREHQQYKTAEFL 194 +KE+ +E E+++++ + R+K +L+E+ Q+N+ + ++ + K + + Sbjct: 1549 QKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQ-M 1607 Query: 195 SKLNTESPDRSACQSAVC--GPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMK 252 S L S +S + C P S + P + + + R+ R+S + +L+KMK Sbjct: 1608 SSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEVT-QRALLRRESEVLDLKEQLEKMK 1666 Query: 253 DEQHQKSE---LLELKRQQQEQERA 274 + K+E L LK Q + A Sbjct: 1667 GDLESKNEEILHLNLKLDMQNSQTA 1691 Score = 35.8 bits (81), Expect = 0.072 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKRE--ESVRIKKEAEEAELQKMKAIQREKSNKLEE 169 GS+ +T + +K++ +QS Q +E ES+ ++ + + ++Q++K S+++EE Sbjct: 1059 GSEKKTALHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEE 1118 Query: 170 KKRLQENLRREAFREHQQYKTAEFLSKL----NTESPDRSACQSAV 211 + E L++ RE + + A LS L N +R A Q A+ Sbjct: 1119 CRSELEVLQQR--RERENREGANLLSMLKADVNLSHSERGALQDAL 1162 Score = 32.7 bits (73), Expect = 0.61 Identities = 40/182 (21%), Positives = 90/182 (49%), Gaps = 17/182 (9%) Query: 113 SQSETEVRQK-QQLQLMQSK---YKQKLKREESVRIKKEAEEAE-LQKMKA---IQREKS 164 S E E++ Q+L+ Q K + +L+ E+ +++E++ A+ L++++A QR +S Sbjct: 2642 SSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQS 2701 Query: 165 NKL----EEKKRLQENLRREAFREHQQYKT--AEFLSKLNTESPDRSACQSAVCGPQSST 218 ++L + ++ ++NL++E EH + + A+ S+L+ D +A +S + Sbjct: 2702 SRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEAL 2761 Query: 219 WKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQ 278 +L S A + LQK+K+E KS +++L+ ++ ++ +H Sbjct: 2762 RHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEE---KSRVVDLQAMLEKVQQQALHS 2818 Query: 279 TE 280 + Sbjct: 2819 QQ 2820 Score = 31.6 bits (70), Expect = 1.4 Identities = 46/231 (19%), Positives = 88/231 (38%), Gaps = 33/231 (14%) Query: 69 LIAPNINRRNE---IQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQL 125 L+ +++R + + + + A L+K KE+ R+ Q+ E Q+Q L Sbjct: 2766 LLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKS---------RVVDLQAMLEKVQQQAL 2816 Query: 126 QLMQSKYKQKLKREESVRIKKEAE---EAELQKMKAIQREKSNKLEEKKRLQENLRREAF 182 Q + K E++R +KE ++ ++ + +RE LE ++ L+ E Sbjct: 2817 HSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELE 2876 Query: 183 REHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKA 242 + H + K E + R + +A W+ W R L+ Sbjct: 2877 QSHPRLKEQEGRKAARRSAEARQSPAAA------EQWR--------KWQRDKEKLRELEL 2922 Query: 243 EENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQ 293 + R L K+K Q +L + E +++H RR + D L+ Sbjct: 2923 QRQRDLHKIKQLQQTVRDL----ESKDEVPGSRLHLGSARRAAGSDADHLR 2969 Score = 30.4 bits (67), Expect = 3.0 Identities = 36/175 (20%), Positives = 77/175 (44%), Gaps = 35/175 (20%) Query: 118 EVRQKQQLQLMQSKYKQKL------------KREESVRIKKEAEEAELQKMKAIQREKSN 165 E K QL L+Q++ K+++ K + R+K + E+ + ++ Q+E +N Sbjct: 674 ETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNN 733 Query: 166 KLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILP 225 K+ E +++E R+ +K + +L E+ ++ ++ + K I+ Sbjct: 734 ----AKQKTELMKQEFQRKETDWKVMK--EELQREAEEKLTLMLLELREKAESEKQTII- 786 Query: 226 RDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280 + L+ E R+LQ Q +++L+L+R EQ+ ++ Q E Sbjct: 787 ----------NKFELREAEMRQLQ-----DQQAAQILDLERSLTEQQ-GRLQQLE 825 Score = 30.0 bits (66), Expect = 4.0 Identities = 36/173 (20%), Positives = 70/173 (40%), Gaps = 6/173 (3%) Query: 107 PRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNK 166 P G + V++ LQLM ++ + +R+E ++A LQ+ + + Sbjct: 844 PTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQL 903 Query: 167 LEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPR 226 L+E+ + Q Q E + L ++ A + A + + L L Sbjct: 904 LQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAA-DLGALET 962 Query: 227 DHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQT 279 H + DSL++ + Q +++E Q ELL ++Q ++ +HQT Sbjct: 963 RHL-----SSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQT 1010 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/181 (20%), Positives = 84/181 (46%), Gaps = 14/181 (7%) Query: 92 EKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEA 151 EK +E+ R + R E E + ++Q + MQ + ++ ++EE K + +E Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE----KMQEQEE 638 Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 ++ + + E+ K+ E++RL E ++E EH++ + E + + + ++ + Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696 Query: 212 CGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQ 271 + TW + + S + ++ R+ ++M EQ +K + E K Q+QE+ Sbjct: 697 QEQEKKTWDQEKMREEESMRE--------REKKMREEEEMMREQEEKMQEQEEKMQEQEE 748 Query: 272 E 272 E Sbjct: 749 E 749 Score = 46.2 bits (108), Expect = 5e-05 Identities = 45/210 (21%), Positives = 93/210 (44%), Gaps = 16/210 (7%) Query: 76 RRNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYK 133 R+ E R E+++ E+ W+++ R R G E E + +Q + ++ + K Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERL-------REQEGKMREQEEKMWRQEKRLREQEK 328 Query: 134 QKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ-ENLRREAFREHQQYKTAE 192 + ++E+ +R +KE E E Q + Q EK + EEK R Q E + R+ R +Q K Sbjct: 329 ELREQEKELREQKELREQEEQMQE--QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386 Query: 193 FLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKLQKMK 252 + + +R Q + + ++ W + R+ K +E K + + Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMR----EQEKMWEQVEKMREEKKMQEQEKKTRDQ 442 Query: 253 DEQHQKSELLELKRQQQEQERAKIHQTEHR 282 +E+ Q+ E + + ++ +E + + E + Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEK 472 Score = 45.4 bits (106), Expect = 9e-05 Identities = 41/207 (19%), Positives = 91/207 (43%), Gaps = 26/207 (12%) Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140 ++I EQE +EK ++ K R S E E + +++ ++M+ + ++ ++EE Sbjct: 684 EKIWEQE--KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741 Query: 141 SVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFL------ 194 K + +E E+ + + E+ K+ E++RL E ++E EH++ + E + Sbjct: 742 ----KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE--QKEKLWEHEKMQEQEKIWEQEEK 795 Query: 195 -----SKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARS---WAYRDSLKAEENR 246 K+ + + + G + W + W + W + + +E + Sbjct: 796 MRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG----QEEKMWGQEEKMWGQEEKMWGQEEK 851 Query: 247 KLQKMKDEQHQKSELLELKRQQQEQER 273 +KM+ ++ + E E R Q+E+ R Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMR 878 Score = 43.5 bits (101), Expect = 3e-04 Identities = 42/221 (19%), Positives = 96/221 (43%), Gaps = 39/221 (17%) Query: 82 RIAEQELANLEK--WKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKRE 139 R EQ++ + E+ W++ R + + E +R+++++ K +++ K + Sbjct: 386 REQEQKMRDQEERMWEQDERLR------------EKEERMREQEKMWEQVEKMREEKKMQ 433 Query: 140 ESVRIKKEAEEAELQKMKAIQREKSNKLEEK---------KRLQENLRREAFREHQQYKT 190 E + ++ EE ++ + +REK + EE+ ++ +EN+ + +E QQ + Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493 Query: 191 AEFLSKL------------NTESPDRSACQSAVCGPQSSTWKLPIL--PRDHSWARSWAY 236 E KL E ++ Q + G + W+ + D W + Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553 Query: 237 RDSLKA--EENRKLQKMKDEQHQKSELLELKRQQQEQERAK 275 RD + ++ +++K EQ +K+ E K +++E+ R + Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594 Score = 39.3 bits (90), Expect = 0.007 Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 25/174 (14%) Query: 116 ETEVRQKQQLQLMQSK---YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKR 172 + E R +++ Q + K ++K++ EE +R ++E + E ++M Q EK + EEK + Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMQ 620 Query: 173 LQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWAR 232 QE E Q+ K E K+ + + + + W+ LP + Sbjct: 621 EQEEKMWE-----QEEKMQEQEEKMWEQ-------EEKMWEQEEKMWEQQRLPEQKE--K 666 Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQ---ERAKIHQTEHRR 283 W + K +E K+Q+ ++E+ + E +E K Q+QE+ ++ K+ + E R Sbjct: 667 LWEHE---KMQEQEKMQE-QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716 Score = 38.5 bits (88), Expect = 0.011 Identities = 33/174 (18%), Positives = 75/174 (43%), Gaps = 11/174 (6%) Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175 E E + +Q + M+ + ++ +EE + K + +E + + RE+ E +K+++E Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600 Query: 176 N----LRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA 231 +E + Q+ K E K+ + + + + W+ + W Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE----QEEKMWE 656 Query: 232 RSWAYRDSLKAEENRKLQKMKDEQHQKSELLE---LKRQQQEQERAKIHQTEHR 282 + K E+ K+Q+ + Q Q+ ++ E ++++ QEQE+ Q + R Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710 Score = 32.7 bits (73), Expect = 0.61 Identities = 33/169 (19%), Positives = 73/169 (43%), Gaps = 7/169 (4%) Query: 121 QKQQLQLMQSKYKQKLKREE----SVRIKKEAEEAELQKMKAIQREKSNKLEEKK--RLQ 174 +K ++QL + K+KL+R + V+ EE Q+ + ++EK + +E+K R + Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSW 234 E LR + + +Q + K E Q Q + ++ + W Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE-EKMW 358 Query: 235 AYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 + ++ +E + ++ + Q+ ++ E +++ ++QE Q E R Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 407 >gi|134152708 arginine and glutamate rich 1 [Homo sapiens] Length = 273 Score = 47.8 bits (112), Expect = 2e-05 Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 23/169 (13%) Query: 114 QSETEVRQKQQLQLMQSKYKQKLKREESVR-----IKKEAEEAELQKMK-AIQREKSNKL 167 + E + ++Q ++ Q + ++KL EE+ R + K EE EL+K K I+RE ++ Sbjct: 103 EEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEE-ELEKRKDEIEREVLRRV 161 Query: 168 EEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRD 227 EE KR+ E ++ E ++ + AE ++ E +R+ + IL + Sbjct: 162 EEAKRIME---KQLLEELERQRQAELAAQKAREEEERAKREELE----------RILEEN 208 Query: 228 HSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKI 276 + R A + AEE ++ + + + H++ LE +RQ+Q++E KI Sbjct: 209 N---RKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKI 254 Score = 31.6 bits (70), Expect = 1.4 Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 7/133 (5%) Query: 163 KSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLP 222 KS+K +K+ + R+ R ++ K+ E ES RS + + + Sbjct: 16 KSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERA 75 Query: 223 ILPRDHS--WARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTE 280 P D + R+ + R SL ++ R+ ++ K E ++ ++ +QQE E I + Sbjct: 76 SSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKI-----RQQEIEEKLIEEET 130 Query: 281 HRRVNNAFLDRLQ 293 RRV R++ Sbjct: 131 ARRVEELVAKRVE 143 Score = 31.2 bits (69), Expect = 1.8 Identities = 43/200 (21%), Positives = 82/200 (41%), Gaps = 16/200 (8%) Query: 3 TRNRVVNSGLGASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAPKGPSRESVVHAGQR 62 +R+R ++ S R P R +R L+ K E ++ Sbjct: 54 SRSRSRSTNTAVSRRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQ 113 Query: 63 RTSAYTLIAPNINRRNEIQRI----AEQELANLEKWKEQNRAKPVHLVP--RRLGGSQSE 116 R I + +R+ A++ LEK K++ + + V +R+ Q Sbjct: 114 RKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLL 173 Query: 117 TEVRQKQQLQLMQSKYKQ---KLKREESVRIKKEAEE--AELQKMKAIQR----EKSNKL 167 E+ +++Q +L K ++ + KREE RI +E AE Q A ++ E+ K+ Sbjct: 174 EELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKI 233 Query: 168 -EEKKRLQENLRREAFREHQ 186 EE+ +L++ +R+ E + Sbjct: 234 HEERMKLEQERQRQQKEEQK 253 Score = 29.3 bits (64), Expect = 6.8 Identities = 36/211 (17%), Positives = 84/211 (39%), Gaps = 18/211 (8%) Query: 90 NLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAE 149 N ++ + ++R++ V +R +S+ R++ + + + + + R + Sbjct: 21 NKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASSPPD 80 Query: 150 EAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQS 209 ++ +R + L+EK++ +E ++ F ++ + E KL E R + Sbjct: 81 RIDIFGRTVSKR---SSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEEL 137 Query: 210 AVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRKL----QKMKDEQHQKSELLELK 265 + K + R+ L+ E K Q +++ + Q+ L + Sbjct: 138 VAKRVEEELEK----------RKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQ 187 Query: 266 RQQQEQERAKIHQTEH-RRVNNAFLDRLQGK 295 + ++E+ERAK + E NN + Q K Sbjct: 188 KAREEEERAKREELERILEENNRKIAEAQAK 218 >gi|157266264 pleckstrin homology-like domain, family B, member 3 [Homo sapiens] Length = 640 Score = 47.8 bits (112), Expect = 2e-05 Identities = 71/290 (24%), Positives = 122/290 (42%), Gaps = 36/290 (12%) Query: 14 ASPASRPTRDPQDPSGRQGELSPVEDQREGLEAAP----------KGPSRESVVHAGQR- 62 A P+SR + Q GE S E R+ EA P SRE V A +R Sbjct: 42 AEPSSRGGAEQQAEEEEVGEGSSTESSRDAPEATPPIAMAATPPASTSSREGVRGAARRL 101 Query: 63 ---RTSAYTLIAPNINRRNEIQRIAEQ-------ELANL--EKWKEQNRAKPVHLVPRRL 110 + A T +A R E+QR ++ E+A L E E+ A+ R L Sbjct: 102 QGQQLEALTRVALMEQRVKELQRQRKELRIEMEVEVALLRGELAGERVAARREEEQLREL 161 Query: 111 GGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEK 170 Q+ +E R +QQ + Q + Q+ R E +R + + +L QRE+ + ++ Sbjct: 162 LEQQAASEQRGRQQREQEQRRLSQERDRLEGLRQRLRKAQGQLDSQPEDQRERLLQGVQE 221 Query: 171 KRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSW 230 R Q ++ + A+ E +++ E S+ E D GPQ K+ L + Sbjct: 222 MREQLDVAQRAY-EDLEFQQLERESRQEEEDRDSP-------GPQVPDPKVQELQASMAQ 273 Query: 231 ARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQ----EQERAKI 276 R A + ++ E +L+ + ++ +S L K+++ QER+++ Sbjct: 274 HRRGALQHRIRVLE-EQLKSLGEQMAAESRGLSRKKEEALQALSQERSRL 322 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 47.0 bits (110), Expect = 3e-05 Identities = 49/216 (22%), Positives = 96/216 (44%), Gaps = 17/216 (7%) Query: 77 RNEIQRIAEQELANLEK--WKEQNRAKPVHLVPRRLGGS-QSETEVRQKQQLQLMQSK-- 131 + E R EQ++ + E+ W++ R + R Q E ++R++++ Q + K Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550 Query: 132 -YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQEN--LRREAFREHQQY 188 ++K++ EE +R ++E + E ++M Q EK + EEK R QE +E + Q+ Sbjct: 551 DQEEKMREEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609 Query: 189 KTAEFLSKL-NTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENRK 247 K E K+ E D+ Q + Q + + W + ++ +E + Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ-------EQEEKMWEQEEKMREQEEKM 662 Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 ++ + Q Q+ ++ E + + Q QE Q E R Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698 Score = 41.2 bits (95), Expect = 0.002 Identities = 39/184 (21%), Positives = 86/184 (46%), Gaps = 26/184 (14%) Query: 114 QSETEVRQKQQLQLMQSK-YKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKR 172 + + +R+K++ Q K ++Q+ K +E RI++ E ++++ + RE+ K++ + Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIRER--EKKMREEEETMREQEEKMQ---K 417 Query: 173 LQENLRREAFREHQQYKTAEFLSKL------------NTESPDRSACQSAVCGPQSSTWK 220 +EN+ + +E QQ + E KL E ++ Q + G + W+ Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477 Query: 221 LPILPRDHSWARSWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQE--QERAKIHQ 278 + + W + ++ +E QKM D++ + E E R+++E +E+ K+ Q Sbjct: 478 QEKMREQED--QMWEQEEKMRDQE----QKMWDQEERMWEQDERLREKEERMREQKKMWQ 531 Query: 279 TEHR 282 E + Sbjct: 532 QEEK 535 Score = 40.4 bits (93), Expect = 0.003 Identities = 39/194 (20%), Positives = 87/194 (44%), Gaps = 20/194 (10%) Query: 92 EKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEA 151 E W+++ + R+ Q E RQ+++L+ + K ++ +EE +R +E Sbjct: 235 EMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEGKMRE---QEEKMR----RQEK 283 Query: 152 ELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSKLNTESPDRSACQSAV 211 L++ + RE+ +L E+K+L+E +E + Q+ K E K+ + + + Sbjct: 284 RLREQEKELREQEKELREQKKLRE---QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340 Query: 212 CGPQSSTWKLPILPRDHSWARSWAYRDSLKAEENR-----KLQKMKDEQHQKSELLELKR 266 + + RD R W + L+ +E R K+ + +++ ++ + E ++ Sbjct: 341 WEQEKQMREQEQKMRDQE-ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399 Query: 267 QQQEQERAKIHQTE 280 + +E+E Q E Sbjct: 400 KMREEEETMREQEE 413 Score = 40.0 bits (92), Expect = 0.004 Identities = 52/229 (22%), Positives = 105/229 (45%), Gaps = 34/229 (14%) Query: 68 TLIAPNINRRN-EIQ---RIAEQELANLE---KWKEQNRAKPVHLVPRRLGGSQSETEVR 120 T+ + ++N E+Q R+AE E + ++ K ++ + L+P+ + E R Sbjct: 179 TITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 238 Query: 121 QKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQRE-KSNKLEEKKRLQENLRR 179 Q+++L RE+ +I+K+ E+ Q+ + ++E K + EEK R QE R Sbjct: 239 QEEEL------------REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286 Query: 180 EAFRE-HQQYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRD 238 E +E +Q K KL + + + + W+ R+ + W + Sbjct: 287 EQEKELREQEKELREQKKLREQ-------EEQMQEQEEKMWEQEEKMREQE-EKMWRQEE 338 Query: 239 SLKAEENR---KLQKMKDEQHQKSELLELKRQQQE--QERAKIHQTEHR 282 L +E + + QKM+D++ + E E R+++E +E+ K+ + E + Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387 Score = 35.4 bits (80), Expect = 0.094 Identities = 37/230 (16%), Positives = 98/230 (42%), Gaps = 43/230 (18%) Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSK-YKQKLKRE 139 QR+ EQ+ E+ K Q + + + + E ++R ++++ + K ++Q+ RE Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIW---------EQEEKIRDQEEMWGQEKKMWRQEKMRE 483 Query: 140 ESVRIKKEAEEAELQKMKAI--------QREKSNKLEEKKRLQENLRREAFREHQQYKTA 191 + ++ ++ E+ Q+ K Q E+ + EE+ R Q+ + ++ + ++ KT Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543 Query: 192 EFLSKLNTESPDRSACQSAVCGPQSSTW----KLPILPRDHSWARSWAYRDSLKAEENRK 247 E + TW K+ R + + + E+ K Sbjct: 544 E---------------------QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582 Query: 248 LQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGKSQ 297 +Q+ +++ ++ E + + ++ +++ K+ + E + D++Q + + Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632 Score = 32.7 bits (73), Expect = 0.61 Identities = 36/182 (19%), Positives = 78/182 (42%), Gaps = 14/182 (7%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKL 136 R E + + EQE +++ +E+ R + + + + E ++ ++++ Q + + Sbjct: 570 REEEEMMREQE-EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628 Query: 137 KREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQQYKTAEFLSK 196 ++EE + ++E + + +KM Q EK + EEK R QE + Q+ K E K Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEK-----MQGQEEKMREQEEK 682 Query: 197 LNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWA---RSWAYRDSLKAEENRKLQKMKD 253 + + + + G + W + W + W + + EE + QK K Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWG----QEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738 Query: 254 EQ 255 ++ Sbjct: 739 QE 740 Score = 32.7 bits (73), Expect = 0.61 Identities = 24/112 (21%), Positives = 55/112 (49%), Gaps = 8/112 (7%) Query: 81 QRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSETEVRQKQQLQLMQSKYKQKLKREE 140 +++ EQE + W+++ + + R E + ++Q + MQ + ++ ++EE Sbjct: 639 EKMQEQEE---KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695 Query: 141 SVRIKKEAEEAELQKM-----KAIQREKSNKLEEKKRLQENLRREAFREHQQ 187 +R ++E + +KM K +E+ + EE+ R Q+ +E EH++ Sbjct: 696 KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747 Score = 31.2 bits (69), Expect = 1.8 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 4/103 (3%) Query: 116 ETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQE 175 E E + ++Q + MQ + ++ ++EE ++ ++E + +KM+ Q EK EEK QE Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG-QEEKMWGQEEKMWGQE 715 Query: 176 NLR--REAFREHQQYKTAEFLSKLNTESPDRSACQSAVCGPQS 216 +E RE ++ + + K+ P+ S C P S Sbjct: 716 EKMWGQEEMREKEE-RIRDQKEKMQERLPEHEERCSEPCLPPS 757 >gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform 4 [Homo sapiens] Length = 522 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%) Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174 ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + + Sbjct: 150 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 209 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232 + L +EA E QQ L+++ D R A ++ + QS PR H + Sbjct: 210 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 262 Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 A R ++AE +L ++ QH + E Q + Q +H E RR Sbjct: 263 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 311 >gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3 [Homo sapiens] Length = 695 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%) Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174 ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + + Sbjct: 323 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 382 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232 + L +EA E QQ L+++ D R A ++ + QS PR H + Sbjct: 383 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 435 Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 A R ++AE +L ++ QH + E Q + Q +H E RR Sbjct: 436 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 484 >gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2 [Homo sapiens] Length = 751 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%) Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174 ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + + Sbjct: 379 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 438 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232 + L +EA E QQ L+++ D R A ++ + QS PR H + Sbjct: 439 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 491 Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 A R ++AE +L ++ QH + E Q + Q +H E RR Sbjct: 492 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540 >gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 [Homo sapiens] Length = 763 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 12/171 (7%) Query: 116 ETEVRQKQQLQLMQSKYKQKLK-REESVRIKKEAEEAELQKMKAIQREKSNKLEEKKRLQ 174 ET + + ++K + +++ R R+KKE EEAELQ + E+ ++ + + Sbjct: 379 ETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMV 438 Query: 175 ENLRREAFREHQQYKTAEFLSKLNTESPD--RSACQSAVCGPQSSTWKLPILPRDHSWAR 232 + L +EA E QQ L+++ D R A ++ + QS PR H + Sbjct: 439 KALEKEAASEKQQL-VETHLARVEAMLNDRRRMALENYLAALQSDP------PRPHRILQ 491 Query: 233 SWAYRDSLKAEENRKLQKMKDEQHQKSELLELKRQQQEQERAKIHQTEHRR 283 A R ++AE +L ++ QH + E Q + Q +H E RR Sbjct: 492 --ALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERR 540 >gi|126362971 serine/threonine kinase 10 [Homo sapiens] Length = 968 Score = 46.6 bits (109), Expect = 4e-05 Identities = 54/238 (22%), Positives = 111/238 (46%), Gaps = 35/238 (14%) Query: 77 RNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLGGSQSET-EVRQKQ-----QLQLMQS 130 +NE++++ Q+ K K + + L+ R Q E E+ K+ + ++ Sbjct: 665 KNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDK 724 Query: 131 KYKQKLKREESVRIKK----EAEEAELQKMKAIQREKSNKLEEKKRLQENLRREAFREHQ 186 + + +K++E +R ++ E EE +LQ+ + +++ L+++ LQ R E R+H+ Sbjct: 725 ERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQ---LKDQYFLQ---RHELLRKHE 778 Query: 187 QYKTAEFLSKLNTESPDRSACQSAVCGPQSSTWKLPILPRDHSWARSWAYRDSLK----- 241 K E + + N ++ + Q +LP + R R Y+ SL Sbjct: 779 --KEREQMQRYNQRMIEQLKVRQ-----QQEKARLPKIQRSEGKTRMAMYKKSLHINGGG 831 Query: 242 --AEENRKLQK--MKDEQHQKSELLELKRQQQEQERAKIHQTEHRRVNNAFLDRLQGK 295 AE+ K+++ ++E+ QKSE L+ +++ + Q R + Q E N + L +LQ + Sbjct: 832 SAAEQREKIKQFSQQEEKRQKSERLQQQQKHENQMRDMLAQCES---NMSELQQLQNE 886 Score = 36.6 bits (83), Expect = 0.042 Identities = 57/289 (19%), Positives = 117/289 (40%), Gaps = 61/289 (21%) Query: 52 SRESVVHAGQRRTSAYTLIAPNINRRNEIQRIAEQELANLEKWKEQNRAKPVHLVPRRLG 111 +R+ VV + + +I+ + + E++ + QEL L +++ Sbjct: 530 TRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEH------------ 577 Query: 112 GSQSETEVRQKQQLQLMQSKYKQKLKREESVRIKKEAEEAELQKMKAIQREKSNKLEEKK 171 +++T++ K +LQL Q + E+ + KK+ + EL+ ++ Q+++ K+E+ Sbjct: 578 --RNQTQLSNKHELQLEQ----MHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDH 631 Query: 172 --RLQENLRREAFREHQQYKTAEFLSKLNTES--------PDRSACQSAVCGPQSSTWKL 221 R +E RR + + Y + KL + P + +S + T K Sbjct: 632 AVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKK 691 Query: 222 PILPRDHSWARSWAYRDSLK--AEENRK---------LQKMKD------------EQHQK 258 +L RD + ++K +NR+ L K ++ E+HQ Sbjct: 692 QLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEMEEHQL 751 Query: 259 SELLELKRQQ-------QEQERAKIHQTEH---RRVNNAFLDRLQGKSQ 297 E +L +QQ Q E + H+ E +R N +++L+ + Q Sbjct: 752 QERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQ 800 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.129 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,101,017 Number of Sequences: 37866 Number of extensions: 763533 Number of successful extensions: 10255 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 250 Number of HSP's successfully gapped in prelim test: 657 Number of HSP's that attempted gapping in prelim test: 5373 Number of HSP's gapped (non-prelim): 3403 length of query: 410 length of database: 18,247,518 effective HSP length: 105 effective length of query: 305 effective length of database: 14,271,588 effective search space: 4352834340 effective search space used: 4352834340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.