Guide to the Human Genome
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Search of human proteins with 50363230

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo
sapiens]
         (612 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo s...  1214   0.0  
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s...  1212   0.0  
gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo s...   221   2e-57
gi|7662394 RAB11 family interacting protein 2 (class I) [Homo sa...    84   5e-16
gi|24308075 RAB11 family interacting protein 5 (class I) [Homo s...    72   2e-12
gi|50428935 BPY2 interacting protein 1 [Homo sapiens]                  47   5e-05
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain...    45   3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   4e-04
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    44   4e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    43   7e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    43   7e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    43   7e-04
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    43   7e-04
gi|157909822 pragmin [Homo sapiens]                                    43   0.001
gi|150170670 piccolo isoform 2 [Homo sapiens]                          42   0.001
gi|150378539 piccolo isoform 1 [Homo sapiens]                          42   0.001
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   0.002
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    40   0.005
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    40   0.006
gi|38373671 SEC24-related protein C [Homo sapiens]                     40   0.006
gi|38373669 SEC24-related protein C [Homo sapiens]                     40   0.006
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        40   0.008
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    40   0.008
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              40   0.008
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    39   0.011
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]     39   0.014
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     39   0.014
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     39   0.014
gi|46852390 coiled-coil domain containing 6 [Homo sapiens]             39   0.014
gi|226437579 NAC alpha domain containing [Homo sapiens]                39   0.018

>gi|50363230 RAB11 family interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 612

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 612/612 (100%), Positives = 612/612 (100%)

Query: 1   MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 60
           MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS
Sbjct: 1   MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 60

Query: 61  LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 120
           LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL
Sbjct: 61  LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 120

Query: 121 EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 180
           EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG
Sbjct: 121 EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 180

Query: 181 EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 240
           EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF
Sbjct: 181 EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 240

Query: 241 RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 300
           RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER
Sbjct: 241 RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 300

Query: 301 IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 360
           IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR
Sbjct: 301 IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 360

Query: 361 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 420
           LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL
Sbjct: 361 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 420

Query: 421 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 480
           DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA
Sbjct: 421 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 480

Query: 481 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK 540
           WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK
Sbjct: 481 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK 540

Query: 541 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 600
           KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR
Sbjct: 541 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 600

Query: 601 IPTQVGKKAGKM 612
           IPTQVGKKAGKM
Sbjct: 601 IPTQVGKKAGKM 612


>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
            sapiens]
          Length = 1283

 Score = 1212 bits (3135), Expect = 0.0
 Identities = 611/612 (99%), Positives = 611/612 (99%)

Query: 1    MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 60
            MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS
Sbjct: 672  MGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS 731

Query: 61   LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 120
            LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL
Sbjct: 732  LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKL 791

Query: 121  EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 180
            EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG
Sbjct: 792  EEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDG 851

Query: 181  EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 240
            EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF
Sbjct: 852  EPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLF 911

Query: 241  RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 300
            RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER
Sbjct: 912  RMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDER 971

Query: 301  IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 360
            IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR
Sbjct: 972  IDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFR 1031

Query: 361  LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 420
            LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL
Sbjct: 1032 LQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSL 1091

Query: 421  DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 480
            DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA
Sbjct: 1092 DNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQA 1151

Query: 481  WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMK 540
            WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNA ATKVANCSLGTATIISENLNNEVMMK
Sbjct: 1152 WVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMK 1211

Query: 541  KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 600
            KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR
Sbjct: 1212 KYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILR 1271

Query: 601  IPTQVGKKAGKM 612
            IPTQVGKKAGKM
Sbjct: 1272 IPTQVGKKAGKM 1283



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 86/405 (21%), Positives = 144/405 (35%), Gaps = 69/405 (17%)

Query: 212 DHLLLPSQEESFSEVPMSEASSAKDTPLFRME----GEDALVTQYQSKASDHEGLLSD-P 266
           +H+ L  Q E+  E+  S  SS+     FR +      + L      + ++  GL SD  
Sbjct: 322 NHVYL-EQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQ 380

Query: 267 LSDLQLVSDFKSPIMADLNLSLPSI--PEVASDDERIDQVEDDGDQVEDDGETAKSSTLD 324
           LS+       KS       ++LPS     + S D R +    + +  ++  E+ K  +  
Sbjct: 381 LSESSTKDSLKS-------MTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRR 433

Query: 325 IGALSLGLVVPCPERGKGPSGEADRLVLG---EGLC-----DFRLQAPQASVTAPSEQTT 376
              LSL  +    +  KG  GE    V G   EG+            P   +   SE+ T
Sbjct: 434 SSLLSL--MTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDT 491

Query: 377 EFGIHKPHLGKSSSLDKQLPGPSGGEEEK-------------------PMGNGSPSPPPG 417
              + +     +   D Q+  P    E K                   P    SP   P 
Sbjct: 492 AAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPT 551

Query: 418 TSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPL 477
             L +P  SPS     P + S  +S  S+  H +  +S +  +          F      
Sbjct: 552 ARLPSPTDSPSSLPPLP-SSSGQASVPSELGHGADTQSSESPSV---------FSSLSSP 601

Query: 478 LQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEV 537
           + A +S S   P+ + P    G AK    P+ P   + T+       + + +  +L  + 
Sbjct: 602 IAAPISTST--PIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSVLGSLFKQ- 658

Query: 538 MMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELED 582
                    P+F   + T D L+    + +ET ++K     ELE+
Sbjct: 659 ---------PSFPANKGTEDSLMG---RTRETGTEKNTSSLELEE 691


>gi|50363228 RAB11 family interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 649

 Score =  221 bits (563), Expect = 2e-57
 Identities = 137/248 (55%), Positives = 154/248 (62%), Gaps = 18/248 (7%)

Query: 370 APSEQTTEFGIHKPHLGKSSSLDKQLPGPS----GGEEEKPMGNGSPSPPPGTSLDNPVP 425
           A SE T E    K    + SSL   + G      G E E P+        PG   +  + 
Sbjct: 415 ANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPL------TVPGREKEGMLM 468

Query: 426 SPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRV-ENFGKRKPLLQAWVSP 484
              P E         S    D    S  ++    + +GS+  + E+    +P  +     
Sbjct: 469 GVKPGED-------ASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKS 521

Query: 485 SETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMKKYSP 544
               P+S+     T + K RLHPVKPMNA ATKVANCSLGTATIISENLNNEVMMKKYSP
Sbjct: 522 EPRPPISSPRAPQTRAVKPRLHPVKPMNATATKVANCSLGTATIISENLNNEVMMKKYSP 581

Query: 545 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 604
           SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ
Sbjct: 582 SDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQ 641

Query: 605 VGKKAGKM 612
           VGKKAGKM
Sbjct: 642 VGKKAGKM 649


>gi|7662394 RAB11 family interacting protein 2 (class I) [Homo
           sapiens]
          Length = 512

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 38/69 (55%), Positives = 53/69 (76%)

Query: 543 SPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 602
           +P D    Y  LT++E++Q ++K KE + +K+  +RELEDYIDNLLVRVMEETP+ILR+P
Sbjct: 440 NPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVP 499

Query: 603 TQVGKKAGK 611
            +  +KAGK
Sbjct: 500 YEPSRKAGK 508


>gi|24308075 RAB11 family interacting protein 5 (class I) [Homo
           sapiens]
          Length = 653

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 14/161 (8%)

Query: 448 HHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 507
           HH+S+ E + K++  G   R      +KP      SP    P+SA P  G+   K     
Sbjct: 496 HHSSSGEEKAKSSWFGL--REAKDPTQKP------SPHPVKPLSAAPVEGSPDRKQSRSS 547

Query: 508 VK-PMNAMATKVANCSLGTATIISE-----NLNNEVMMKKYSPSDPAFAYAQLTHDELIQ 561
           +   +++   K+   + G+   +++      + +   +K  +  D +  Y  LTHDELI 
Sbjct: 548 LSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELIS 607

Query: 562 LVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIP 602
           L+L+++  +S+++  V+ELE YID LLVR+ME +P +L+IP
Sbjct: 608 LLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIP 648


>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
          Length = 1059

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 91/380 (23%), Positives = 143/380 (37%), Gaps = 56/380 (14%)

Query: 77  GDRDLESQAGSLVESKARDAAEE--VAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKT 134
           G RD   + G L+ +  R   E   VA   P  A  P      RK E+     R+ +K  
Sbjct: 477 GSRDSSKREG-LLATHPRPGQERPGVARKEPARAEAP------RKTEKEAKTPRELKKDP 529

Query: 135 KKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPP--ESPHAEDSE 192
           K  VS ++      A +    L + ++    +   A S + +   G PP    P +  S 
Sbjct: 530 KPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHS---GFPPVANGPRSPPSL 586

Query: 193 RESVTTPGPATCGAPAS-----PADHL-LLPSQEESFSEVPMSEASSAKDTPLFRMEGED 246
           R    +P  A CG+PAS     P+  L  +P+ EE   E+P+    +A   P  R    +
Sbjct: 587 RCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPL----AASSIPRPRTPSPE 642

Query: 247 ALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVED 306
           +    ++S A   E L   PL   +   D  SP +    ++ PS+P         +   D
Sbjct: 643 S----HRSPAEGSERLSLSPLRGGEAGPD-ASPTVTTPTVTTPSLPAEVGSPHSTE--VD 695

Query: 307 DGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQA 366
           +   V  +     S+      LSL L  P   R   P  + D  ++     + R   P A
Sbjct: 696 ESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPH-DVDLCLVSPCEFEHRKAVPMA 754

Query: 367 SVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS 426
              A    + +          SS+  ++  G  G EE  P           TS+   +P+
Sbjct: 755 PAPASPGSSND----------SSARSQERAGGLGAEETPP-----------TSVSESLPT 793

Query: 427 PSPSEIFPVTHSFPSSAHSD 446
            S S+  P+    P +A SD
Sbjct: 794 LSDSDPVPLA---PGAADSD 810


>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain and
            proline-rich containing [Homo sapiens]
          Length = 1435

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 15/159 (9%)

Query: 59   LSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 118
            LS++   A S V +  AG    L +    LVES A+ A   + P LP  A      S++ 
Sbjct: 867  LSITGTLAESIVAQALAG----LSAARDQLVESLAQQATVTMPPALP--APDGGEPSLLE 920

Query: 119  KLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNAS 178
              E  GL   +++++ K++     Q + E  ++    LV    S  +E  P   +A    
Sbjct: 921  PGELEGLFFPEEKEEEKEKDDSPPQKWPE--LSHGLHLVPFIHSAAEEAEPEPELAAPGE 978

Query: 179  DGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLP 217
            D EP   P A  S       P PA  G PA P   + LP
Sbjct: 979  DAEPQAGPSARGS-------PSPAAPGPPAGPLPRMDLP 1010


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 21/258 (8%)

Query: 10  EKNTSSLELEESLPEQPETGRQEE----ELPRFPCKKQDYSPSSGEAQEVPFALSLSSDG 65
           EK  S ++ E   PE+ ++  +EE    E  + P K++  SP   ++ E    L + S  
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765

Query: 66  AVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGL 125
           A +P  E A         +A S V+ + + + E+   PL   A  P  +  + K EE+  
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVK-SPEKAKSPLKEDAKAP--EKEIPKKEEVKS 822

Query: 126 NLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPES 185
            +++++K  + +V    +   EE         E   S  +E          A   E P+ 
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE----------APKKEAPK- 871

Query: 186 PHAEDSERESVTTPGPATCGAPASPA-DHLLLPSQE-ESFSEVPMSEASSAKD-TPLFRM 242
           P  E+ +  +V  P  +   A    A D   +P+ E E+ ++V + E +  K+ T + + 
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931

Query: 243 EGEDALVTQYQSKASDHE 260
           E +DA   +    A   E
Sbjct: 932 EPDDAKAKEPSKPAEKKE 949



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 87/440 (19%), Positives = 162/440 (36%), Gaps = 41/440 (9%)

Query: 2   GRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS- 60
           G+  E G E+     E E   P   E    E+E  + P K++  SP+  ++ E   A S 
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA-KSPVKEEAKSPAEAKSPEKEEAKSP 541

Query: 61  ---LSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMM 117
               S + A SP  E           +A S  E+K+ +  E  +P     A V S +   
Sbjct: 542 AEVKSPEKAKSPAKE-----------EAKSPPEAKSPEKEEAKSP-----AEVKSPEKAK 585

Query: 118 RKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQEL-NPAWSVAGN 176
              +E   +  + +   K +    E+    ++ A A   V+  +  P E+ +P  + +  
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEE---AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642

Query: 177 ASDGEPPE---SPHAEDSER-ESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEAS 232
             + + PE   SP  E+++  E   +P  A   +P      +   ++    ++ P+ E  
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE-- 700

Query: 233 SAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIP 292
            AK     +   ++   +  ++K+   E   +   +   +  + KSP  A       ++ 
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL- 759

Query: 293 EVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVL 352
           +V S + +    E+     +   E AKS   +         V  PE+ K P  E  +   
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKE--------EVKSPEKAKSPLKEDAKAPE 811

Query: 353 GEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSP 412
            E      +++P      P E   +    K    K+ +  K        +EE P    +P
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK-KEAP 870

Query: 413 SPPPGTSLDNPVPSPSPSEI 432
            P      +  V  P  S++
Sbjct: 871 KPKVEEKKEPAVEKPKESKV 890


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 72/288 (25%), Positives = 108/288 (37%), Gaps = 46/288 (15%)

Query: 169 PAWSVAGNASDGEPPESPHAEDSERESVTTPGPA----TCGAPASPADHLLLPSQEESFS 224
           P+ S A  A  G P  +P   + ++E    P PA    T G PA P      P   +   
Sbjct: 74  PSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPC-----PPSPDLIY 128

Query: 225 EVPMSEASSAKDTPLFRMEGEDALVTQYQSKAS---DHEGLLSDPLSDLQLVSDFKSPIM 281
           ++P +  +     P   +E  D   T  +  +S   D     S PL+ +      + P  
Sbjct: 129 KIPRASGTQLA-APRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAP----QPPGE 183

Query: 282 ADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPER-- 339
            D    +P  P+  ++ E    +E +G +       A  S L   +  L L    PE   
Sbjct: 184 DDAPYDVPLTPKPPAELE--PDLEWEGGREPGPPIYAAPSNLKRASALLNL-YEAPEELL 240

Query: 340 GKGPSGEADRLVLGEGLCDFRLQAPQA-------SVTAPSEQTTEFGI--------HKPH 384
             G  G  D     EG+ D  L  P+A          A  +Q T   +        H+P 
Sbjct: 241 ADGEGGGTD-----EGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPR 295

Query: 385 LGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPP---GTSLDNPVPSPSP 429
           L  + SL ++ P P+    E P  +  PSP P   G+  D P+P P P
Sbjct: 296 LPSAESLSRR-PLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPP 342


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 99/475 (20%), Positives = 166/475 (34%), Gaps = 59/475 (12%)

Query: 31  QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVE 90
           +E  +P F    +    S+G+A       S SSD   + V    +     +++ + S  E
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE--TDVEGKPSVKPAQVKASSVSTKE 232

Query: 91  SKARDAAE------EVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKK-------TKKR 137
           S AR AA       +V P +  GA  P+     +K EE   +  +  +        T+ +
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 138 VSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPE-----SPHAEDSE 192
           V  SE++    A +  A    G  + P     A +VA     G+P E     S  + DSE
Sbjct: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350

Query: 193 RESVTTPG---------PATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRME 243
            E+               +  GA ++PA      S  +  +  P  +   A         
Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAPAPPGKTGPAVAKAQAGKR 406

Query: 244 GEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIM-ADLNLSLPSIPEVASDDERID 302
            ED+  +  +S + +     + P      V    +P   +    + P+ P          
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466

Query: 303 QVEDDGDQVEDDGETAKSSTLDIGALS---------LG---LVVPCPERGKGPSGEADRL 350
           QV   G Q ED   +++ S  D  AL+         LG    V P    G GP G+    
Sbjct: 467 QV---GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523

Query: 351 VLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNG 410
           V    +      A        SE ++E          S S D ++P      +EK +GN 
Sbjct: 524 VPPGKVGPATPSAQVGKWEEDSESSSE--------ESSDSSDGEVPTAVAPAQEKSLGNI 575

Query: 411 SPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 465
             + P  +    P     P  +         ++ S    + +A+S++   A  +A
Sbjct: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA 630


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 99/475 (20%), Positives = 166/475 (34%), Gaps = 59/475 (12%)

Query: 31  QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVE 90
           +E  +P F    +    S+G+A       S SSD   + V    +     +++ + S  E
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE--TDVEGKPSVKPAQVKASSVSTKE 232

Query: 91  SKARDAAE------EVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKK-------TKKR 137
           S AR AA       +V P +  GA  P+     +K EE   +  +  +        T+ +
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 138 VSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPE-----SPHAEDSE 192
           V  SE++    A +  A    G  + P     A +VA     G+P E     S  + DSE
Sbjct: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350

Query: 193 RESVTTPG---------PATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRME 243
            E+               +  GA ++PA      S  +  +  P  +   A         
Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAPAPPGKTGPAVAKAQAGKR 406

Query: 244 GEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIM-ADLNLSLPSIPEVASDDERID 302
            ED+  +  +S + +     + P      V    +P   +    + P+ P          
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466

Query: 303 QVEDDGDQVEDDGETAKSSTLDIGALS---------LG---LVVPCPERGKGPSGEADRL 350
           QV   G Q ED   +++ S  D  AL+         LG    V P    G GP G+    
Sbjct: 467 QV---GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523

Query: 351 VLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNG 410
           V    +      A        SE ++E          S S D ++P      +EK +GN 
Sbjct: 524 VPPGKVGPATPSAQVGKWEEDSESSSE--------ESSDSSDGEVPTAVAPAQEKSLGNI 575

Query: 411 SPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 465
             + P  +    P     P  +         ++ S    + +A+S++   A  +A
Sbjct: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA 630


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 99/475 (20%), Positives = 166/475 (34%), Gaps = 59/475 (12%)

Query: 31  QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVE 90
           +E  +P F    +    S+G+A       S SSD   + V    +     +++ + S  E
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE--TDVEGKPSVKPAQVKASSVSTKE 232

Query: 91  SKARDAAE------EVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKK-------TKKR 137
           S AR AA       +V P +  GA  P+     +K EE   +  +  +        T+ +
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 138 VSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPE-----SPHAEDSE 192
           V  SE++    A +  A    G  + P     A +VA     G+P E     S  + DSE
Sbjct: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350

Query: 193 RESVTTPG---------PATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRME 243
            E+               +  GA ++PA      S  +  +  P  +   A         
Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAPAPPGKTGPAVAKAQAGKR 406

Query: 244 GEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIM-ADLNLSLPSIPEVASDDERID 302
            ED+  +  +S + +     + P      V    +P   +    + P+ P          
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466

Query: 303 QVEDDGDQVEDDGETAKSSTLDIGALS---------LG---LVVPCPERGKGPSGEADRL 350
           QV   G Q ED   +++ S  D  AL+         LG    V P    G GP G+    
Sbjct: 467 QV---GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523

Query: 351 VLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNG 410
           V    +      A        SE ++E          S S D ++P      +EK +GN 
Sbjct: 524 VPPGKVGPATPSAQVGKWEEDSESSSE--------ESSDSSDGEVPTAVAPAQEKSLGNI 575

Query: 411 SPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 465
             + P  +    P     P  +         ++ S    + +A+S++   A  +A
Sbjct: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA 630


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 99/475 (20%), Positives = 166/475 (34%), Gaps = 59/475 (12%)

Query: 31  QEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVE 90
           +E  +P F    +    S+G+A       S SSD   + V    +     +++ + S  E
Sbjct: 175 EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDE--TDVEGKPSVKPAQVKASSVSTKE 232

Query: 91  SKARDAAE------EVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKK-------TKKR 137
           S AR AA       +V P +  GA  P+     +K EE   +  +  +        T+ +
Sbjct: 233 SPARKAAPAPGKVGDVTPQVKGGALPPA--KRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 138 VSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPE-----SPHAEDSE 192
           V  SE++    A +  A    G  + P     A +VA     G+P E     S  + DSE
Sbjct: 291 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350

Query: 193 RESVTTPG---------PATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRME 243
            E+               +  GA ++PA      S  +  +  P  +   A         
Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKE----SPRKGAAPAPPGKTGPAVAKAQAGKR 406

Query: 244 GEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIM-ADLNLSLPSIPEVASDDERID 302
            ED+  +  +S + +     + P      V    +P   +    + P+ P          
Sbjct: 407 EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466

Query: 303 QVEDDGDQVEDDGETAKSSTLDIGALS---------LG---LVVPCPERGKGPSGEADRL 350
           QV   G Q ED   +++ S  D  AL+         LG    V P    G GP G+    
Sbjct: 467 QV---GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGP 523

Query: 351 VLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNG 410
           V    +      A        SE ++E          S S D ++P      +EK +GN 
Sbjct: 524 VPPGKVGPATPSAQVGKWEEDSESSSE--------ESSDSSDGEVPTAVAPAQEKSLGNI 575

Query: 411 SPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSA 465
             + P  +    P     P  +         ++ S    + +A+S++   A  +A
Sbjct: 576 LQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAA 630


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 48/202 (23%), Positives = 78/202 (38%), Gaps = 12/202 (5%)

Query: 353 GEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSP 412
           G+GL      A  AS + P E+        P L KSS +   +   +GG    P+ + S 
Sbjct: 518 GQGLSSRESHAHSASESKPKERPAI----PPKLSKSSPVGSPVSPSAGGPPVSPLADLSD 573

Query: 413 SPPPGTSLDNPVPSPSPSEIFP------VTHSFPSSAHSDTHHTSTAESQKKATAEGSAG 466
               G+S+    PS  P++  P      V  S PS        +S +E ++     G+  
Sbjct: 574 GSSGGSSIGPQPPSQGPADPAPSCRTNGVAISDPSRCPQPA-ASSASEQRRPRFQAGTWS 632

Query: 467 RVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAK-HRLHPVKPMNAMATKVANCSLGT 525
           R     + + + Q  +S S        P   + S   HRLHP    +   +KV      +
Sbjct: 633 RQCRIEEEEEVEQELLSHSWGRETKNGPTDHSNSTTWHRLHPTDGSSGQNSKVGTGMSKS 692

Query: 526 ATIISENLNNEVMMKKYSPSDP 547
           A+   E   +   ++ +SP  P
Sbjct: 693 ASFAFEFPKDRSGIETFSPPPP 714


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 360 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 417
           ++ A QA     S Q T  G  KP   L   +    Q PGP+    ++P     PS  PG
Sbjct: 448 KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 418 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 475
           ++   P  P P+ PS   P +   PS        ++   S  K +A+ S   V   G  K
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565

Query: 476 PLLQAWVSPSETHPVS 491
           PL    VSPS   P S
Sbjct: 566 PLQPPTVSPSAKQPPS 581



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 110/522 (21%), Positives = 176/522 (33%), Gaps = 74/522 (14%)

Query: 2   GRTRETGTEKN--TSSLELEESLP-EQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 58
           GR  + G  K+  T +   E+ LP   P T   +E   R   K++  S     +    F 
Sbjct: 103 GRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS-----SMMPGFL 157

Query: 59  LSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 118
             +++  AVS V       D   +S+A S  E+  +    +     P G   P +     
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEA-SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216

Query: 119 KLEEMGLNLRKD---QKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAG 175
           K         +D   Q  T K +S  +    +    G    ++G +  PQ  +    +  
Sbjct: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 176 NASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAK 235
           +AS    P++  A+    ESV    P+    P+ P      P Q+ +  + P  +    K
Sbjct: 277 DASR---PQTKQADIVRGESVKPSLPS----PSKP------PIQQPTPGKPPAQQPGHEK 323

Query: 236 DTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVA 295
             P               +K       L+ PL+  Q     K P+        P+ P + 
Sbjct: 324 SQP-------------GPAKPPAQPSGLTKPLA--QQPGTVKPPVQPPGTTKPPAQP-LG 367

Query: 296 SDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEG 355
                  Q   +    E  G  A +    +G          P +  GP+    + V   G
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT--------PAQQPGPAKPPTQQV---G 416

Query: 356 LCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPP 415
                 Q P     A +   T+  + +P  GK   +  Q  GP     ++      PS  
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK---IPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 416 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 475
           PG +   P   P P++  P     P SA   +    + +   +             G  K
Sbjct: 474 PGPAKPPP-QQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQP-----------GPAK 518

Query: 476 PLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATK 517
           P  Q    P  T P S QPG+   SA+ +  P KP    +TK
Sbjct: 519 PSPQ---QPGSTKPPSQQPGSAKPSAQ-QPSPAKPSAQQSTK 556



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%)

Query: 403 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 449
           + KPM  GSP+PP      G ++  P  SP P E        +  +T + P S  +    
Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925

Query: 450 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 498
           T T           +++    +  G  G     G   P+ QA  +PS+  P S  P   T
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983

Query: 499 GSA 501
           G A
Sbjct: 984 GQA 986


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 42/136 (30%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 360 RLQAPQASVTAPSEQTTEFGIHKP--HLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPG 417
           ++ A QA     S Q T  G  KP   L   +    Q PGP+    ++P     PS  PG
Sbjct: 448 KIPAQQAGPGKTSAQQT--GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 418 TSLDNPV-PSPS-PSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 475
           ++   P  P P+ PS   P +   PS        ++   S  K +A+ S   V   G  K
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565

Query: 476 PLLQAWVSPSETHPVS 491
           PL    VSPS   P S
Sbjct: 566 PLQPPTVSPSAKQPPS 581



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 110/522 (21%), Positives = 176/522 (33%), Gaps = 74/522 (14%)

Query: 2   GRTRETGTEKN--TSSLELEESLP-EQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFA 58
           GR  + G  K+  T +   E+ LP   P T   +E   R   K++  S     +    F 
Sbjct: 103 GRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS-----SMMPGFL 157

Query: 59  LSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMR 118
             +++  AVS V       D   +S+A S  E+  +    +     P G   P +     
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEA-SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216

Query: 119 KLEEMGLNLRKD---QKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAG 175
           K         +D   Q  T K +S  +    +    G    ++G +  PQ  +    +  
Sbjct: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 176 NASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAK 235
           +AS    P++  A+    ESV    P+    P+ P      P Q+ +  + P  +    K
Sbjct: 277 DASR---PQTKQADIVRGESVKPSLPS----PSKP------PIQQPTPGKPPAQQPGHEK 323

Query: 236 DTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVA 295
             P               +K       L+ PL+  Q     K P+        P+ P + 
Sbjct: 324 SQP-------------GPAKPPAQPSGLTKPLA--QQPGTVKPPVQPPGTTKPPAQP-LG 367

Query: 296 SDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEG 355
                  Q   +    E  G  A +    +G          P +  GP+    + V   G
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT--------PAQQPGPAKPPTQQV---G 416

Query: 356 LCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPP 415
                 Q P     A +   T+  + +P  GK   +  Q  GP     ++      PS  
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK---IPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 416 PGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRK 475
           PG +   P   P P++  P     P SA   +    + +   +             G  K
Sbjct: 474 PGPAKPPP-QQPGPAKPPPQQ---PGSAKPPSQQPGSTKPPPQQP-----------GPAK 518

Query: 476 PLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATK 517
           P  Q    P  T P S QPG+   SA+ +  P KP    +TK
Sbjct: 519 PSPQ---QPGSTKPPSQQPGSAKPSAQ-QPSPAKPSAQQSTK 556



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 27/123 (21%)

Query: 403 EEKPMGNGSPSPP-----PGTSLDNPVPSPSPSE--------IFPVTHSFPSSAHSDTHH 449
           + KPM  GSP+PP      G ++  P  SP P E        +  +T + P S  +    
Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-PKSQPTTPQE 925

Query: 450 TST-----------AESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGT 498
           T T           +++    +  G  G     G   P+ QA  +PS+  P S  P   T
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA-PAPSQP-PTSQGPPKST 983

Query: 499 GSA 501
           G A
Sbjct: 984 GQA 986


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 68/268 (25%), Positives = 98/268 (36%), Gaps = 42/268 (15%)

Query: 21   SLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALS----LSSDGAVSPVGEL--- 73
            S P +P      EELP  P  +   SP       +P  LS     ++  A+SP+GEL   
Sbjct: 901  SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960

Query: 74   -AAGGDRDLESQ-AGSLVESKARDAAEEVA---PPLPMGASVPSIDSMMRKLEEMGLNLR 128
              A GD D ES  A  ++E+      E       P+P     PS  S +     + +   
Sbjct: 961  FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL 1020

Query: 129  KDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGE------- 181
              Q     + S   Q       +  AL +    S P  L+P   V G + + E       
Sbjct: 1021 PPQCSPLLQHSLVPQNSPPSQCSPPALPL----SVPSPLSPIGKVVGVSDEAELHEMETE 1076

Query: 182  ---PPESPHAEDSERESVTTP-GPATCGAPA---------------SPADHLLLPSQEES 222
                PE P  E S    + +P G  +C AP+               +P D +  P  +  
Sbjct: 1077 KVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPE 1136

Query: 223  FSEVPMSEASSAKDTPLFRMEGEDALVT 250
              + P S AS  K +P+     E A VT
Sbjct: 1137 PGQTPGSLASELKGSPVLLDPEELAPVT 1164



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 59/271 (21%), Positives = 89/271 (32%), Gaps = 25/271 (9%)

Query: 182 PPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSA--KDTPL 239
           P ESP +   E   ++ P      +P   A HL  P +E   S  P     S   + +P 
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512

Query: 240 FRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDE 299
             +E       +    +   E  LS P     L   F+   ++     LP+ P    +  
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEAS 570

Query: 300 RIDQVEDDGDQVEDDGETAKSSTLDIGAL-----SLGLVVPCPERGKGPSGEADRLVLGE 354
           R+    ++        E+  S   +   L        L  P  E    P  EA RL    
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS--- 627

Query: 355 GLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSL---DKQLPGPSGGEEEKPMGNGS 411
                    P+ S  +P  + +      P + + S L    +  P P       P     
Sbjct: 628 -------PPPEDSPMSPPPEESPMS-PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP 679

Query: 412 PSPPPGTSLDNPVPSPSPSEIFPVTHSFPSS 442
            SPPP  S  +P P  SP+   P     P+S
Sbjct: 680 TSPPPEASRLSPPPEDSPTS--PPPEDSPAS 708



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 46/186 (24%), Positives = 61/186 (32%), Gaps = 16/186 (8%)

Query: 337 PERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSS-SLDKQL 395
           PE G  P+ E D L +    C  + +    +   P E        KP LGK+   L+ QL
Sbjct: 375 PEPGDTPTDEPDALYVA---CQGQPKGGHVTSMQPKEPGPLQCEAKP-LGKAGVQLEPQL 430

Query: 396 PGPSGGE-------EEKPMG----NGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAH 444
             P   E       EE P+         SPPP  S  +P P   P+   P          
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490

Query: 445 SDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHR 504
                    ES      E S           P  ++  SP+   P+S  P A   S    
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550

Query: 505 LHPVKP 510
             P+ P
Sbjct: 551 ESPLSP 556



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 10/78 (12%)

Query: 394  QLPGPSGGEEEKP-MGNGSPSPPPGTSLDNPVPS--PSPSEIFPVTHSFPSSAHSDTHHT 450
            +LP P G     P +G   P+PPP +  +   PS  PSPS   P     P +      H 
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT------HP 4341

Query: 451  STAESQKKATAEGSAGRV 468
             T + Q   T E   GRV
Sbjct: 4342 GTPKPQ-GPTLEPPPGRV 4358


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 65/289 (22%), Positives = 109/289 (37%), Gaps = 34/289 (11%)

Query: 158 EGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLP 217
           E  SS  +E  P      + +  +PP +  A +S  +S  +       AP+ PA      
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNS 387

Query: 218 SQEESF-SEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDF 276
           S + +  ++ P  + ++A   P+    G+  L  +  S +S+ E   S+     ++V+  
Sbjct: 388 SNKPAVTTKSPAVKPAAAPKQPV--GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATT 445

Query: 277 KSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGE-TAKSSTLDIGALSLGLVVP 335
           K    A   LSLP+  + A    R    + D    E++ E T+KS+         G   P
Sbjct: 446 KPKATAKAALSLPA--KQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503

Query: 336 ----CPERGKGPSG----------EADRLVLGEGLCDFRLQAPQASVTA----------- 370
                 ++GK  S           E +  + G+G    R QAP+A+ T+           
Sbjct: 504 SKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG--SPRPQAPKANGTSALTAQNGKAAK 561

Query: 371 -PSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGT 418
              E+  E       + KS SL K+    +  E E P         P T
Sbjct: 562 NSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNT 610



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 44/148 (29%)

Query: 362 QAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGS---------P 412
           +AP  + T P+ +++          + SS D++       E++KPM N            
Sbjct: 251 KAPVKAATTPTRKSSS--------SEDSSSDEE------EEQKKPMKNKPGPYSSVPPPS 296

Query: 413 SPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFG 472
           +PPP  SL    P  +  +  PV  S  SS  SD    S++E +K               
Sbjct: 297 APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESD----SSSEEEK--------------- 337

Query: 473 KRKPLLQAWVSPSETHPVSAQPGAGTGS 500
             KP  +A VS + T P  A+  A + S
Sbjct: 338 --KPPTKAVVSKATTKPPPAKKAAESSS 363


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 108/511 (21%), Positives = 176/511 (34%), Gaps = 71/511 (13%)

Query: 9   TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 68
           +E  + S    +S  E   +  +E E    P  + +  P +    ++   L+  S  A  
Sbjct: 471 SESTSDSDSSSDSESESSSSDSEENEPLETPAPEPE--PPTTNKWQLDNWLTKVSQPAAP 528

Query: 69  PVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMM-----RKLEEM 123
           P G  +    R      GS   + +++ +E   PP    +  P           R  ++ 
Sbjct: 529 PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKS 588

Query: 124 GLNLRKDQKKT------KKRVSFSEQLFTEEAVAGA---ALLVEGHSSCPQELNPAWSVA 174
                  Q++T      KK V  S +  +  ++ G     LL  G      +  P     
Sbjct: 589 PAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTK 648

Query: 175 GN---ASDGEP-PESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSE 230
           G    A+  EP P  P + + ++   + P P+   +   PA   +     E F+ VP++E
Sbjct: 649 GRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTE 708

Query: 231 ASSAKDTPL-FRMEG-EDALVTQYQSKASDHEGLLSDPLSDLQLVSDFK-----SPIMAD 283
           +     +    R  G   A+V Q  S+    +  L  PL D +L+S  +       +M  
Sbjct: 709 SQGPPHSGSGSRTSGCRQAVVVQEDSR----KDRLPLPLRDTKLLSPLRDTPPPQSLMVK 764

Query: 284 LNLSLPS-IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKG 342
           + L L S IP+      R  + ED          + K S+     L+           K 
Sbjct: 765 ITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLA-----------KK 813

Query: 343 PSGEADRLVLGEGLCD---FRLQAPQASVTAPSEQT-TEFGIHKPHLGKSSSLDKQL--P 396
             GEA+R       CD    RL+    S ++ S  +  E    KP    S S  K++  P
Sbjct: 814 RKGEAER------DCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPP 867

Query: 397 GPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHS--DTHHTSTAE 454
            P     +KP                P    S  E        P SA S    H  S+  
Sbjct: 868 PPVSSSSQKPA--------------KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIP 913

Query: 455 SQKKATAEGSAGRVENFGKRKPLLQAWVSPS 485
            Q++   +GS    E+ G        +  PS
Sbjct: 914 KQRRVEGKGSRSSSEHKGSSGDTANPFPVPS 944


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 47/206 (22%), Positives = 69/206 (33%), Gaps = 5/206 (2%)

Query: 2   GRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSL 61
           G+  +   +   SS    + LP     G     +   P   Q Y P    AQ       +
Sbjct: 84  GQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGM 143

Query: 62  SSDGAVSPV---GELAAGGDRDLESQAGSLVESKARDAAEE-VAPPLPMGASVPSIDSMM 117
              GAV+P      L  G    L S +GS   S    +  +  APPL      P I +  
Sbjct: 144 QISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQ 203

Query: 118 RKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGH-SSCPQELNPAWSVAGN 176
           R       +         +  S +  L   ++  G ++    H SS PQ L P   + G 
Sbjct: 204 RSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGP 263

Query: 177 ASDGEPPESPHAEDSERESVTTPGPA 202
                P  SP     + +   + GPA
Sbjct: 264 LGPLPPMHSPQQPGYQPQQNGSFGPA 289


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 47/206 (22%), Positives = 69/206 (33%), Gaps = 5/206 (2%)

Query: 2   GRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSL 61
           G+  +   +   SS    + LP     G     +   P   Q Y P    AQ       +
Sbjct: 84  GQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGM 143

Query: 62  SSDGAVSPV---GELAAGGDRDLESQAGSLVESKARDAAEE-VAPPLPMGASVPSIDSMM 117
              GAV+P      L  G    L S +GS   S    +  +  APPL      P I +  
Sbjct: 144 QISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQ 203

Query: 118 RKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGH-SSCPQELNPAWSVAGN 176
           R       +         +  S +  L   ++  G ++    H SS PQ L P   + G 
Sbjct: 204 RSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGP 263

Query: 177 ASDGEPPESPHAEDSERESVTTPGPA 202
                P  SP     + +   + GPA
Sbjct: 264 LGPLPPMHSPQQPGYQPQQNGSFGPA 289


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/392 (19%), Positives = 133/392 (33%), Gaps = 52/392 (13%)

Query: 146  TEEAVAGAALLVEGHSSCPQE-LNPAWSVAGNASDGEPPESPHAEDSERESVTT------ 198
            T   +  A++ V   +  P   L+PA S             P ++D+     TT      
Sbjct: 740  TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVE 799

Query: 199  PGPATCGAPAS-PADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKAS 257
            P   + G+P+S P  H+   S      E   +  SS   T        D    + +   +
Sbjct: 800  PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 859

Query: 258  DHEG----LLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVED 313
             H      + S P +   LV +  S   +  + +    P+ ++   R ++          
Sbjct: 860  SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE---------- 909

Query: 314  DGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAP-- 371
               TA  S+ D       +V+P         GE+    +  G       A   S T P  
Sbjct: 910  --STASHSSQDATGT---IVLPARSTTSVLLGESTTSPISSG--SMETTALPGSTTTPGL 962

Query: 372  SEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSE 431
            SE++T F  H      +++L       SG  EE       P     T+  +   +P  S 
Sbjct: 963  SERSTTF--HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSR 1020

Query: 432  IFPVTHSFPSSAHS---DTHHTSTAESQKKATAEGSAGRVE-----------NFGKRKPL 477
                +HS P S  +       T++  SQ+  T+  S+G  +           +FG+    
Sbjct: 1021 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 1080

Query: 478  LQAWVSPSETHPV---SAQPGAGTGSAKHRLH 506
              +  +P  TH      +   +G   A  R+H
Sbjct: 1081 FHS--NPGSTHTTLFPDSTTSSGIVEASTRVH 1110



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 74/355 (20%), Positives = 125/355 (35%), Gaps = 56/355 (15%)

Query: 174  AGNASDGEPPESPHAEDSERESVTTPGPA---TCGAPASPADHLLLPSQEESFSEVPMSE 230
            A + + G   ES     S   + TTP PA   T G       +   P   ++    P S+
Sbjct: 3430 ASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM-HFPESD 3488

Query: 231  ASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPS 290
             +S +        GE++      S +S    + S P +   LV +  S   +  + +   
Sbjct: 3489 TTSGR--------GEESTT----SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 3536

Query: 291  IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRL 350
             P+ ++   R ++             TA  S+ D       +V+P         GE+   
Sbjct: 3537 FPDSSTTSGRSEE------------STASHSSQDATGT---IVLPARSTTSVLLGESTTS 3581

Query: 351  VLGEGLCDFRLQAPQASVTAP--SEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMG 408
             +  G       A   S T P  SE++T F  H      +++L       SG  EE    
Sbjct: 3582 PISSG--SMETTALPGSTTTPGLSEKSTTF--HSSPRSPATTLSPASTTSSGVSEESTTS 3637

Query: 409  NGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHS---DTHHTSTAESQKKATAEGSA 465
            +  P     T+  +   +P  S     +HS P S  +       T++  SQ+  T+  S+
Sbjct: 3638 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSS 3697

Query: 466  GRVE-----------NFGKRKPLLQAWVSPSETHPV---SAQPGAGTGSAKHRLH 506
            G  +           +FG+      +  SP  TH      +   +G   A  R+H
Sbjct: 3698 GSTDTALSPGSTTALSFGQESTTFHS--SPGSTHTTLFPDSTTSSGIVEASTRVH 3750



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 72/352 (20%), Positives = 120/352 (34%), Gaps = 50/352 (14%)

Query: 174  AGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASS 233
            A + + G   ES     S   + TTP PA         +     S   S   +   E+S+
Sbjct: 1873 ASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESST 1932

Query: 234  AKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPE 293
            A          E++      S +S    + S P +   LV +  S   +  + +    P+
Sbjct: 1933 ASG------RSEESRT----SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD 1982

Query: 294  VASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLG 353
             ++   R ++             TA  S+ D       +V+P         GE+    + 
Sbjct: 1983 SSTTSGRSEE------------STASHSSQDATGT---IVLPARSTTSVLLGESTTSPIS 2027

Query: 354  EGLCDFRLQAPQASVTAP--SEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGS 411
             G       A   S T P  SE++T F  H      +++L       SG  EE    +  
Sbjct: 2028 SG--SMETTALPGSTTTPGLSEKSTTF--HSSPRSPATTLSPASTTSSGVSEESTTSHSR 2083

Query: 412  PSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHS---DTHHTSTAESQKKATAEGSAGRV 468
            P     T+  +   +P  S     +HS P S  +       T++  SQ+  T+  S G  
Sbjct: 2084 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143

Query: 469  E-----------NFGKRKPLLQAWVSPSETHPV---SAQPGAGTGSAKHRLH 506
            +           +FG+      +  SP  TH      +   +G   A  R+H
Sbjct: 2144 DTALSPGSTTALSFGQESTTFHS--SPGSTHTTLFPDSTTSSGIVEASTRVH 2193



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 70/337 (20%), Positives = 117/337 (34%), Gaps = 44/337 (13%)

Query: 192  ERESVTTPGPATCGAPASPADHLLLPSQEES---FSEVPMS-EASSAKDTPLFRMEGEDA 247
            E  + +   P +  +  SPA        EES   +S  P S E +    TP   + GE+ 
Sbjct: 2353 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412

Query: 248  LVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDD 307
              T +   AS H  L ++         D  +  + + + + P  P  AS    +      
Sbjct: 2413 -TTFHSRPASTHTTLFTE---------DSTTSGLTEESTAFPGSP--ASTQTGLPATLTT 2460

Query: 308  GDQVEDDGETAKSSTLDIGALSLGLVV-PCPERGKGPSGEADRLVLGEGLCDFRLQAPQA 366
             D  E+      S+T    + S G  + P      G  GE+    L     +        
Sbjct: 2461 ADLGEE------STTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 2514

Query: 367  SVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS 426
            +  + SE++T F  +       ++L       SG  EE    +  P     T+  +   +
Sbjct: 2515 TTPSLSEKSTTF--YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT 2572

Query: 427  PSPSEIFPVTHSFPSSAHS---DTHHTSTAESQKKATAEGSAGRVE-----------NFG 472
            P  S     +HS P S  +       T++  SQ+  T+  S G  +           +FG
Sbjct: 2573 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFG 2632

Query: 473  KRKPLLQAWVSPSETHPV---SAQPGAGTGSAKHRLH 506
            +      +  SP  TH      +   +G   A  R+H
Sbjct: 2633 QESTTFHS--SPGSTHTTLFPDSTTSSGIVEASTRVH 2667



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 11/110 (10%)

Query: 370  APSEQTTE--FGIHKP-HLGKSSSLDKQLPG----PSGGEEEKPMGNGSPSPPPGTSLDN 422
            +P+  TT    G   P  L  SS+    LPG    PS  E+       SP  P  T    
Sbjct: 1399 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT-SPRSPDATLSPA 1457

Query: 423  PVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAE---SQKKATAEGSAGRVE 469
               S   SE    +HS P S H+     ST     SQ+  T+  S G  E
Sbjct: 1458 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 1507



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 41/156 (26%), Positives = 57/156 (36%), Gaps = 16/156 (10%)

Query: 363  APQASVTA--PSEQTTEFGIHKPHLGKSSSLDKQ---LPGPS---GGEEEKPMGNGSPSP 414
            +P A+ TA  P+   T   + +P     SS   +   LPG +   G  E+      SP  
Sbjct: 3198 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 3257

Query: 415  PPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTST---AESQKKATAEGSAGRVENF 471
            P  T       S   SE    +HS P S H+     ST     SQ+   +  S G  +  
Sbjct: 3258 PDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT- 3316

Query: 472  GKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHP 507
                 L     + S   P S    +G GS +  L P
Sbjct: 3317 ----TLSPGSTTASSLGPESTTFHSGPGSTETTLLP 3348



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 11/110 (10%)

Query: 370  APSEQTTE--FGIHKP-HLGKSSSLDKQLPG----PSGGEEEKPMGNGSPSPPPGTSLDN 422
            +P+  TT    G   P  L  SS+    LPG    PS  E+       SP  P  T    
Sbjct: 4039 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT-SPRSPDATLSPA 4097

Query: 423  PVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAE---SQKKATAEGSAGRVE 469
               S   SE    +HS P S H+     ST     SQ+  T+  S G  E
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 35/129 (27%), Positives = 45/129 (34%), Gaps = 12/129 (9%)

Query: 352  LGEGLCDFRLQAPQASVTAPSEQTTEFGI----HKPHLGKSSSLDKQLPG----PSGGEE 403
            LGE    F   +     T    ++T  G+        L  SS+    LPG    PS  E+
Sbjct: 2937 LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2996

Query: 404  EKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAE---SQKKAT 460
                   SP  P  T       S   SE    +HS P S H+     ST     SQ+   
Sbjct: 2997 STTFYT-SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055

Query: 461  AEGSAGRVE 469
            +  S G  E
Sbjct: 3056 SHSSQGSTE 3064


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/392 (19%), Positives = 133/392 (33%), Gaps = 52/392 (13%)

Query: 146 TEEAVAGAALLVEGHSSCPQE-LNPAWSVAGNASDGEPPESPHAEDSERESVTT------ 198
           T   +  A++ V   +  P   L+PA S             P ++D+     TT      
Sbjct: 227 TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVE 286

Query: 199 PGPATCGAPAS-PADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKAS 257
           P   + G+P+S P  H+   S      E   +  SS   T        D    + +   +
Sbjct: 287 PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 346

Query: 258 DHEG----LLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVED 313
            H      + S P +   LV +  S   +  + +    P+ ++   R ++          
Sbjct: 347 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE---------- 396

Query: 314 DGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAP-- 371
              TA  S+ D       +V+P         GE+    +  G       A   S T P  
Sbjct: 397 --STASHSSQDATGT---IVLPARSTTSVLLGESTTSPISSG--SMETTALPGSTTTPGL 449

Query: 372 SEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSE 431
           SE++T F  H      +++L       SG  EE       P     T+  +   +P  S 
Sbjct: 450 SERSTTF--HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSR 507

Query: 432 IFPVTHSFPSSAHS---DTHHTSTAESQKKATAEGSAGRVE-----------NFGKRKPL 477
               +HS P S  +       T++  SQ+  T+  S+G  +           +FG+    
Sbjct: 508 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 567

Query: 478 LQAWVSPSETHPV---SAQPGAGTGSAKHRLH 506
             +  +P  TH      +   +G   A  R+H
Sbjct: 568 FHS--NPGSTHTTLFPDSTTSSGIVEASTRVH 597



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 11/110 (10%)

Query: 370 APSEQTTE--FGIHKP-HLGKSSSLDKQLPG----PSGGEEEKPMGNGSPSPPPGTSLDN 422
           +P+  TT    G   P  L  SS+    LPG    PS  E+       SP  P  T    
Sbjct: 886 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT-SPRSPDATLSPA 944

Query: 423 PVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAE---SQKKATAEGSAGRVE 469
              S   SE    +HS P S H+     ST     SQ+  T+  S G  E
Sbjct: 945 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 994


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 106/517 (20%), Positives = 174/517 (33%), Gaps = 66/517 (12%)

Query: 17   ELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQ--EVPFALSLSSDGAVSPVGELA 74
            E E    E     + E E    P  + +  P S + +  E  + +   S+GA +P  E  
Sbjct: 1855 EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKE 1914

Query: 75   AGGDRD----LESQAGSLVESKARDAAE-EVAPPLPMGASVPSIDSMMRKLEEMGLNLRK 129
            A  + +    LE++     ES+  +A E E A     G + P  + +  +  E      +
Sbjct: 1915 AQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE-----EE 1969

Query: 130  DQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQ---ELNPAWSVAGNASDGEPPESP 186
             Q +++   +   ++ T+EA  G A         P+   E+  A   A   SDG   + P
Sbjct: 1970 AQPESEDVEALEVEVETQEA-EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQ-P 2027

Query: 187  HAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGED 246
             +E  E + V      T G     +D +  P  EE   E    E   A+       E  D
Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAE-GEVQEAEGEAHPESEDVD 2086

Query: 247  ALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMA------DLNLSLPSIP-EVASDDE 299
            A   + +++         +   + Q     ++P            +  P    E   + E
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146

Query: 300  RIDQVEDDGD-QVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCD 358
             ++  + +G+ Q E +G  A+ +  +      G+  P  E    P  E       EG   
Sbjct: 2147 GVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQ 2206

Query: 359  FRLQAPQASVTAPSEQTTEFGIHKPHL---------GKSSSLDKQLPGPSGG-------- 401
              L+  +A       Q    G+  P           G++    K  P  S G        
Sbjct: 2207 PELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEAS 2266

Query: 402  EEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVT-----------------HSFPSSAH 444
            E   P+    P+PPP    D P   P  S+  P +                 H    +  
Sbjct: 2267 ESSSPVPEDRPTPPPSPGGDTPHQRPG-SQTGPSSSRASSWGNCWQKDSENDHVLGDTRS 2325

Query: 445  SDTHHTSTAESQKKAT---AEGSAGRVEN--FGKRKP 476
             D   T T  +++KAT    E S    E    G R P
Sbjct: 2326 PDAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTP 2362



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 75/351 (21%), Positives = 121/351 (34%), Gaps = 38/351 (10%)

Query: 71   GELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKD 130
            GE AAGGD+D     G+  E      AE  A P   G   P  +   ++ E         
Sbjct: 1816 GEAAAGGDQDPGQSDGA--EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAE--------- 1864

Query: 131  QKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAED 190
                 +    SE +   EA   A    +  S   +     W V   +   E PE+     
Sbjct: 1865 ----GEAQPESEDVEAPEAEGEA----QPESEDVETPEAEWEVQPESEGAEAPEAEKEAQ 1916

Query: 191  SERESV---TTPG---PATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEG 244
             E ESV    T G   P + GA A  A+     ++ ++  E  + E+  A++      E 
Sbjct: 1917 PETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESED 1976

Query: 245  EDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQV 304
             +AL  + +++ ++ E   + P S+     D ++P             +  SD       
Sbjct: 1977 VEALEVEVETQEAEGE---AQPESE-----DVEAPEAEGEMQEAEEEAQPESDGVEAQPK 2028

Query: 305  EDDGDQVEDDGETAKSSTLDIGALSLGLVVP-CPERGKGPSGEADRLVLGEGLCDFRLQA 363
             +  +  E +GET K+   D    S G+  P   E  +   GE       EG      + 
Sbjct: 2029 SEGEEAQEVEGETQKTEG-DAQPESDGVEAPEAEEEAQEAEGEVQE---AEGEAHPESED 2084

Query: 364  PQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSP 414
              A       Q    G+  P     +   + +  P    E +P   G  +P
Sbjct: 2085 VDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135



 Score = 36.2 bits (82), Expect = 0.091
 Identities = 46/189 (24%), Positives = 61/189 (32%), Gaps = 29/189 (15%)

Query: 291 IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVP-----CPERGKGPSG 345
           IP   SD          G++  D  + +    L +G    G V P     C + G  P+ 
Sbjct: 776 IPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQ 835

Query: 346 EADRLVLGEG--LCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEE 403
           EA R    E   LC      P      P  +++  G         SS      GP G   
Sbjct: 836 EAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCG------STGSSHQSTARGPGG--- 886

Query: 404 EKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEG 463
                    SP  GT    P PSP P+       S  SSA         +E +   +  G
Sbjct: 887 ---------SPQEGTRQPGPTPSPGPNS----GASRRSSASQGAGSRGLSEEKTLRSGGG 933

Query: 464 SAGRVENFG 472
             G+ E  G
Sbjct: 934 PQGQEEASG 942


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 76/295 (25%), Positives = 103/295 (34%), Gaps = 58/295 (19%)

Query: 168 NPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVP 227
           +P   V    SD   P S     S+  S  +  P     P+ P+D   LPS   S S VP
Sbjct: 186 SPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVP 245

Query: 228 M----------------SEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLS---DPLS 268
                            S+ S   D P        +L++   S  SD   LLS    P S
Sbjct: 246 SPPSDVPSLLSGVPSPPSDISPPSDVP--------SLLSDVPSLPSDVPSLLSGVPSPPS 297

Query: 269 DL-QLVSDFKSPIMADLNLSLPS-IPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIG 326
           D+  L+SD  SP         PS +P   SD   +  V      V        S   D+ 
Sbjct: 298 DVPSLLSDVPSP---------PSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVP 348

Query: 327 ALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLG 386
            LS    VP P            + L  G+       P   ++      + + +  PH  
Sbjct: 349 LLS---GVPSP---------LSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRL 396

Query: 387 KSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPS-----PSPSEIFPVT 436
              SL   +P    G    P  +G PS P G  + + VPS     PSPS + P+T
Sbjct: 397 DVPSLLSDVPSLLSGVPSSP--SGVPSLPSGVPILSGVPSLPSGVPSPSGV-PIT 448


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 84/368 (22%), Positives = 140/368 (38%), Gaps = 70/368 (19%)

Query: 9   TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 68
           +++    L L +     P    Q+ +L   P      +  S +A+E    L+L  D A++
Sbjct: 667 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE---GLTLPQDSAMT 723

Query: 69  PVGELAAGGDRDLESQ-----AGSLVESKARDAA-----EEVAPPLPMG----ASVP--- 111
           P   L    D DL S      A +LV  +A +         + PPLP+     +S P   
Sbjct: 724 PPLPLQ---DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780

Query: 112 SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 171
           +  +++ +  E GL L +D   T         L                SS P+ +  A 
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL----------------SSAPKPVAAAT 824

Query: 172 SVAGNASDG-----EPPESPHAEDSERESVTTPGPATCGAPASPA--DHLLLPSQEESFS 224
            V+  A +G     +   +P     + +  + P P     P S    + L LP      +
Sbjct: 825 LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884

Query: 225 EVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDL--QLVSDFKSPIMA 282
            +P+ +           +     L    Q++A    G  ++P++ +  Q V +   P  A
Sbjct: 885 PLPLQDTGPTSGPEPLAVATPQTL----QAEAGCAPG--TEPVATMAQQEVGEALGPRPA 938

Query: 283 --DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETA------KSSTLDIGALSLGLVV 334
             + N +LP++PE A+    +DQV+ D  Q   +  T         STL + ALSL    
Sbjct: 939 PEEKNAALPTVPEPAA----LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL---- 990

Query: 335 PCPERGKG 342
           P P  G G
Sbjct: 991 PEPASGAG 998


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 84/368 (22%), Positives = 140/368 (38%), Gaps = 70/368 (19%)

Query: 9   TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 68
           +++    L L +     P    Q+ +L   P      +  S +A+E    L+L  D A++
Sbjct: 667 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE---GLTLPQDSAMT 723

Query: 69  PVGELAAGGDRDLESQ-----AGSLVESKARDAA-----EEVAPPLPMG----ASVP--- 111
           P   L    D DL S      A +LV  +A +         + PPLP+     +S P   
Sbjct: 724 PPLPLQ---DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780

Query: 112 SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 171
           +  +++ +  E GL L +D   T         L                SS P+ +  A 
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL----------------SSAPKPVAAAT 824

Query: 172 SVAGNASDG-----EPPESPHAEDSERESVTTPGPATCGAPASPA--DHLLLPSQEESFS 224
            V+  A +G     +   +P     + +  + P P     P S    + L LP      +
Sbjct: 825 IVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884

Query: 225 EVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDL--QLVSDFKSPIMA 282
            +P+ +           +     L    Q++A    G  ++P++ +  Q V +   P  A
Sbjct: 885 PLPLQDTGPTSGPEPLAVATPQTL----QAEAGCAPG--TEPVATMAQQEVGEALGPRPA 938

Query: 283 --DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETA------KSSTLDIGALSLGLVV 334
             + N +LP++PE A+    +DQV+ D  Q   +  T         STL + ALSL    
Sbjct: 939 PEEKNAALPTVPEPAA----LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL---- 990

Query: 335 PCPERGKG 342
           P P  G G
Sbjct: 991 PEPASGAG 998


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 84/368 (22%), Positives = 140/368 (38%), Gaps = 70/368 (19%)

Query: 9   TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 68
           +++    L L +     P    Q+ +L   P      +  S +A+E    L+L  D A++
Sbjct: 667 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE---GLTLPQDSAMT 723

Query: 69  PVGELAAGGDRDLESQ-----AGSLVESKARDAA-----EEVAPPLPMG----ASVP--- 111
           P   L    D DL S      A +LV  +A +         + PPLP+     +S P   
Sbjct: 724 PPLPLQ---DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780

Query: 112 SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 171
           +  +++ +  E GL L +D   T         L                SS P+ +  A 
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL----------------SSAPKPVAAAT 824

Query: 172 SVAGNASDG-----EPPESPHAEDSERESVTTPGPATCGAPASPA--DHLLLPSQEESFS 224
            V+  A +G     +   +P     + +  + P P     P S    + L LP      +
Sbjct: 825 IVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 884

Query: 225 EVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDL--QLVSDFKSPIMA 282
            +P+ +           +     L    Q++A    G  ++P++ +  Q V +   P  A
Sbjct: 885 PLPLQDTGPTSGPEPLAVATPQTL----QAEAGCAPG--TEPVATMAQQEVGEALGPRPA 938

Query: 283 --DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETA------KSSTLDIGALSLGLVV 334
             + N +LP++PE A+    +DQV+ D  Q   +  T         STL + ALSL    
Sbjct: 939 PEEKNAALPTVPEPAA----LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL---- 990

Query: 335 PCPERGKG 342
           P P  G G
Sbjct: 991 PEPASGAG 998


>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
          Length = 474

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 7/81 (8%)

Query: 379 GIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHS 438
           G+H  H+G S  + +    PS      P     P+PPP  +   PV  P P    P+  +
Sbjct: 397 GLHVQHMGTSHGITR----PSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPT 452

Query: 439 FPSSAHSD---THHTSTAESQ 456
            PS+A S    + H++   SQ
Sbjct: 453 VPSAATSQPTPSQHSAHPSSQ 473


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 38.5 bits (88), Expect = 0.018
 Identities = 83/368 (22%), Positives = 140/368 (38%), Gaps = 70/368 (19%)

Query: 9    TEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVS 68
            +++    L L +     P    Q+ +L   P      +  S +A+E    L+L  D A++
Sbjct: 707  SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE---GLTLPQDSAMT 763

Query: 69   PVGELAAGGDRDLESQ-----AGSLVESKARDAA-----EEVAPPLPMG----ASVP--- 111
            P   L    D DL S      A ++V  +A +         + PPLP+     +S P   
Sbjct: 764  PPLPLQ---DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 820

Query: 112  SIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAW 171
            +  +++ +  E GL L +D   T         L                SS P+ +  A 
Sbjct: 821  AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL----------------SSAPKPVAAAT 864

Query: 172  SVAGNASDG-----EPPESPHAEDSERESVTTPGPATCGAPASPA--DHLLLPSQEESFS 224
             V+  A +G     +   +P     + +  + P P     P S    + L LP      +
Sbjct: 865  PVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 924

Query: 225  EVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDL--QLVSDFKSPIMA 282
             +P+ +           +     L    Q++A    G  ++P++ +  Q V +   P  A
Sbjct: 925  PLPLQDTGPTSGPEPLAVATPQTL----QAEAGCAPG--TEPVATMAQQEVGEALGPRPA 978

Query: 283  --DLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETA------KSSTLDIGALSLGLVV 334
              + N +LP++PE A+    +DQV+ D  Q   +  T         STL + ALSL    
Sbjct: 979  PEEKNAALPTVPEPAA----LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL---- 1030

Query: 335  PCPERGKG 342
            P P  G G
Sbjct: 1031 PEPASGAG 1038


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.126    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,813,426
Number of Sequences: 37866
Number of extensions: 1624313
Number of successful extensions: 10413
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 407
Number of HSP's that attempted gapping in prelim test: 9148
Number of HSP's gapped (non-prelim): 1636
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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