Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 50355978

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
         (291 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                 593   e-170
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                  336   2e-92
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                  317   1e-86
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...   100   2e-21
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        91   9e-19
gi|4506049 hematopoietically expressed homeobox [Homo sapiens]         86   3e-17
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       86   3e-17
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    85   9e-17
gi|19923391 homeobox D3 [Homo sapiens]                                 84   1e-16
gi|14149611 empty spiracles homeobox 2 [Homo sapiens]                  83   2e-16
gi|4504465 homeobox B2 [Homo sapiens]                                  83   2e-16
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        82   6e-16
gi|63054872 ladybird homeobox 1 [Homo sapiens]                         82   6e-16
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]           82   7e-16
gi|118582284 msh homeobox 1 [Homo sapiens]                             81   9e-16
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        81   1e-15
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi...    80   3e-15
gi|94536800 empty spiracles homolog 1 [Homo sapiens]                   79   4e-15
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       79   6e-15
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       79   6e-15
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    78   1e-14
gi|89257348 homeo box HB9 [Homo sapiens]                               78   1e-14
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               78   1e-14
gi|19923352 NK3 homeobox 1 [Homo sapiens]                              77   1e-14
gi|23397672 homeobox D4 [Homo sapiens]                                 77   2e-14
gi|27886557 msh homeobox 2 [Homo sapiens]                              76   4e-14
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     76   4e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              76   4e-14
gi|10140847 homeobox A2 [Homo sapiens]                                 75   5e-14
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    75   9e-14

>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score =  593 bits (1528), Expect = e-170
 Identities = 291/291 (100%), Positives = 291/291 (100%)

Query: 1   MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP 60
           MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP
Sbjct: 1   MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLP 60

Query: 61  ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL 120
           ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL
Sbjct: 61  ASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSL 120

Query: 121 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE 180
           GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE
Sbjct: 121 GGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE 180

Query: 181 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM 240
           LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM
Sbjct: 181 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM 240

Query: 241 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 291
           LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
Sbjct: 241 LQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 291


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score =  336 bits (861), Expect = 2e-92
 Identities = 193/331 (58%), Positives = 218/331 (65%), Gaps = 66/331 (19%)

Query: 10  PHPHEPISFGIDQILNSPDQDSA--PAPRGPDGASYLGGPPGGR---------------- 51
           P   EPISFGIDQILNSPDQ     PA R  DG   LG   GG                 
Sbjct: 11  PGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGG 70

Query: 52  --------PGATYPSLPASFAGLGAPFEDAGSYSVNLSLA-------------------P 84
                   PG   P  PA   G  +     GSY+VN++LA                    
Sbjct: 71  AGAYGTGGPGG--PGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSA 128

Query: 85  AGVIRVPAHRPLPGAV--PPPLPSALPAMPSVPT---VSSLGGLNFPWMESSRRFVKDRF 139
           AGVIRVPAHRPL GAV  P PL + LP +PSVP    V++L GL FPWMES+RR+ KDRF
Sbjct: 129 AGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRF 188

Query: 140 TAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAAL 199
           T              GHPYQNRTPPK+KKPRTSF+R+QICELEKRFHRQKYLASAERAAL
Sbjct: 189 T--------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAAL 234

Query: 200 AKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPD 259
           AK+LKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQA+R++LQLQ +AFQKSL   +  D
Sbjct: 235 AKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPAD 294

Query: 260 PLCLHNSSLFALQNLQPWEEDSSKVPAVTSL 290
           PLC+HNSSLFALQNLQPW +DS+K+ +VTS+
Sbjct: 295 PLCVHNSSLFALQNLQPWSDDSTKITSVTSV 325


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score =  317 bits (811), Expect = 1e-86
 Identities = 183/289 (63%), Positives = 201/289 (69%), Gaps = 28/289 (9%)

Query: 10  PHPHEPISFGIDQILNSPDQDSAPAP--RGPDGASYLGGPPGGRPGATYPSLPASFAGLG 67
           PH HEPISFGIDQIL+ P+         RG  G    G   GG  GA+      S A L 
Sbjct: 12  PH-HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPL- 69

Query: 68  APFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGG----- 122
                 GS  V     P GVIRVPAHRPLP  VPPP   A    P+VP  S LGG     
Sbjct: 70  -----PGSSGVG----PGGVIRVPAHRPLP--VPPPAGGA----PAVPGPSGLGGAGGLA 114

Query: 123 -LNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICEL 181
            L FPWM+S RRF KDR TAA  L+PF+ TRRIGHPYQNRTPPKRKKPRTSFSR Q+ EL
Sbjct: 115 GLTFPWMDSGRRFAKDRLTAA--LSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLEL 172

Query: 182 EKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLML 241
           E+RF RQKYLASAERAALAK+L+MTDAQVKTWFQNRRTKWRRQTAEEREAER +A RL+L
Sbjct: 173 ERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLL 232

Query: 242 QLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSL 290
            LQ DA  + L   + PDPLCLHNSSLFALQNLQPW ED +KV +V+ L
Sbjct: 233 HLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAED-NKVASVSGL 280


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score =  100 bits (249), Expect = 2e-21
 Identities = 86/263 (32%), Positives = 119/263 (45%), Gaps = 29/263 (11%)

Query: 6   SAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAG 65
           SA TPH       GI+ IL+ P    A       GA+     P G   ++  S  AS A 
Sbjct: 91  SAATPH-------GINDILSRPSMPVA------SGAALPSASPSGSSSSSSSSASASSAS 137

Query: 66  LGAPFEDAGSYSVNLSLAPAGVIR-VPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN 124
             A    A + + +   +PAG++  +P    L    PPP P  L   PS   V+++G   
Sbjct: 138 AAAAAAAAAAAAAS---SPAGLLAGLPRFSSLS---PPPPPPGLYFSPSAAAVAAVGRYP 191

Query: 125 FPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRT----PPKRKKPRTSFSRVQICE 180
            P  E   R     +       P+   R    P+Q         KRK  R +FS  QI  
Sbjct: 192 KPLAELPGR-TPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFA 250

Query: 181 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEE----REAERQQA 236
           LEK F + KYLA  ERA LA SL MT++QVK WFQNRRTKWR++ A E    ++ +  + 
Sbjct: 251 LEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSET 310

Query: 237 SRLMLQLQHDAFQKSLNDSIQPD 259
            RL    +++      N  + P+
Sbjct: 311 ERLKGASENEEEDDDYNKPLDPN 333


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 91.3 bits (225), Expect = 9e-19
 Identities = 55/134 (41%), Positives = 77/134 (57%), Gaps = 5/134 (3%)

Query: 102 PPLPSALPAMPSVPTVSSLGGLN-FPWMESSR---RFVKDRFTAAAALTPFTVTRRIGHP 157
           PP+P      P     S  GGL   P++  S    +  K+R   A + +P +   R G  
Sbjct: 82  PPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGA 141

Query: 158 YQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNR 217
            + +    +KK RT FSR Q+ +LE  F  ++YL+S+ERA LA SL++T+ QVKTWFQNR
Sbjct: 142 -ERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNR 200

Query: 218 RTKWRRQTAEEREA 231
           R KW+RQ + E EA
Sbjct: 201 RNKWKRQLSAELEA 214


>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 74/230 (32%), Positives = 100/230 (43%), Gaps = 27/230 (11%)

Query: 8   QTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGAS-YLG-GPPGGRPGATYPSLPASFAG 65
           Q PHP  P +  +   L +P     PA   P      LG GP    P  T PS  +SF  
Sbjct: 2   QYPHPG-PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTS 60

Query: 66  LGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNF 125
           L +P+                  R P + P P   P     +  A+ +       GG  +
Sbjct: 61  LVSPY------------------RTPVYEPTP-IHPAFSHHSAAALAAAYGPGGFGGPLY 101

Query: 126 PWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRF 185
           P+     R V D   A     P      +  P+  R   KRK  +  FS  Q  ELEK+F
Sbjct: 102 PFP----RTVNDYTHALLRHDPLGKPL-LWSPFLQRPLHKRKGGQVRFSNDQTIELEKKF 156

Query: 186 HRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQ 235
             QKYL+  ER  LAK L++++ QVKTWFQNRR KWRR   E  ++ +++
Sbjct: 157 ETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKE 206


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 46/91 (50%), Positives = 59/91 (64%), Gaps = 1/91 (1%)

Query: 142 AAALTPFTVTRRIGHPYQNRTPP-KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALA 200
           AAA TP     + G     + P  ++KK RT FSR Q+ +LE  F  ++YL+S+ERA LA
Sbjct: 202 AAAATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLA 261

Query: 201 KSLKMTDAQVKTWFQNRRTKWRRQTAEEREA 231
            SL +T+ QVK WFQNRR KW+RQ A E EA
Sbjct: 262 ASLHLTETQVKIWFQNRRNKWKRQLAAELEA 292


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 84.7 bits (208), Expect = 9e-17
 Identities = 40/67 (59%), Positives = 51/67 (76%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
           ++KK RT FSR Q+ +LE  F  ++YL+SAERA LA SL++T+ QVK WFQNRR KW+RQ
Sbjct: 202 RKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQ 261

Query: 225 TAEEREA 231
            A E EA
Sbjct: 262 LAAELEA 268


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 50/145 (34%), Positives = 72/145 (49%), Gaps = 26/145 (17%)

Query: 95  PLPGAVPPPLPSALPAMPS--VPTVSSLGGLN------------FPWMESSRRFVKDRFT 140
           P P   PP LP + P  P   VP     GG N            FPWM+ SR+  K + +
Sbjct: 117 PQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNS 176

Query: 141 AAAALTPFTVTRRIGHPYQNRTPP--KRKKPRTSFSRVQICELEKRFHRQKYLASAERAA 198
            A A          G   ++++PP    K+ RT+++  Q+ ELEK FH  +YL    R  
Sbjct: 177 CATA----------GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVE 226

Query: 199 LAKSLKMTDAQVKTWFQNRRTKWRR 223
           +A  L +T+ Q+K WFQNRR K+++
Sbjct: 227 MANLLNLTERQIKIWFQNRRMKYKK 251


>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
          Length = 252

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 62/204 (30%), Positives = 86/204 (42%), Gaps = 7/204 (3%)

Query: 35  PRGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHR 94
           P  P   SY    P       + S  A+ AG G        ++  +S  P   + V    
Sbjct: 30  PIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVP 89

Query: 95  PLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRI 154
           P       PLPS+    P   +        +PW+    R++  RF           T   
Sbjct: 90  PPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQG-------NDTSPE 142

Query: 155 GHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWF 214
                N    K K+ RT+FS  Q+  LE  F +  Y+  AER  LA SL +T+ QVK WF
Sbjct: 143 SFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWF 202

Query: 215 QNRRTKWRRQTAEEREAERQQASR 238
           QNRRTK++RQ  EE  ++ QQ  +
Sbjct: 203 QNRRTKFKRQKLEEEGSDSQQKKK 226


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 52/148 (35%), Positives = 72/148 (48%), Gaps = 21/148 (14%)

Query: 99  AVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTA-----AAALTPFTVTRR 153
           A+PPP P  LPA P  P         FPWM+  +   K   +A     AA+  P +    
Sbjct: 77  ALPPPPPPPLPAAPPAP--------EFPWMKEKKSAKKPSQSATSPSPAASAVPAS---G 125

Query: 154 IGHPYQNRTPPKR-----KKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDA 208
           +G P      P+      ++ RT+++  Q+ ELEK FH  KYL    R  +A  L +T+ 
Sbjct: 126 VGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTER 185

Query: 209 QVKTWFQNRRTKWRRQTAEEREAERQQA 236
           QVK WFQNRR K +RQT      + + A
Sbjct: 186 QVKVWFQNRRMKHKRQTQHREPPDGEPA 213


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 43/97 (44%), Positives = 61/97 (62%), Gaps = 3/97 (3%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
           K +K RT+F+  Q+ +LE+ F RQKYL+  +R  LA SL +TD QVKTW+QNRRTKW+RQ
Sbjct: 177 KPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQ 236

Query: 225 TAEEREAERQQASRLMLQLQHDA---FQKSLNDSIQP 258
           TA   E   +  +   LQ    +   + +SL  ++ P
Sbjct: 237 TAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDP 273


>gi|63054872 ladybird homeobox 1 [Homo sapiens]
          Length = 281

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 43/81 (53%), Positives = 58/81 (71%), Gaps = 1/81 (1%)

Query: 159 QNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRR 218
           Q +TP KR+K RT+F+  QI ELEKRF  QKYL+ A+R  +A+ L +T+AQV TWFQNRR
Sbjct: 118 QRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRR 177

Query: 219 TKWRRQTAEEREAERQQASRL 239
            K +R   EE +A+ + A +L
Sbjct: 178 AKLKRD-LEEMKADVESAKKL 197


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score = 81.6 bits (200), Expect = 7e-16
 Identities = 59/202 (29%), Positives = 84/202 (41%), Gaps = 21/202 (10%)

Query: 33  PAPR---GPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIR 89
           PAP     P    Y+G  P   P   +P    +      P  D   Y V        V  
Sbjct: 24  PAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPP--DISPYEVPPLADDPAVAH 81

Query: 90  VPAHRPLPGAVPPPLPSALP--AMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTP 147
           +  H P   A+P P     P  A P V    +   L FPWM+S++        A  A   
Sbjct: 82  LHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAA 141

Query: 148 FTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTD 207
                          P + K+ RT+++R Q+ ELEK F   KY++   R  LA  L +T+
Sbjct: 142 --------------EPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTE 187

Query: 208 AQVKTWFQNRRTKWRRQTAEER 229
             +K WFQNRR KW+++  ++R
Sbjct: 188 RHIKIWFQNRRMKWKKEEDKKR 209


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 81.3 bits (199), Expect = 9e-16
 Identities = 71/233 (30%), Positives = 96/233 (41%), Gaps = 39/233 (16%)

Query: 42  SYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVP 101
           S  G P GG  G    +  A+ A +GA  E+     V+ SL P  V  + A    PGA  
Sbjct: 19  SAFGKPAGGGAGQAPSAAAATAAAMGAD-EEGAKPKVSPSLLPFSVEALMADHRKPGAKE 77

Query: 102 ---------------------PPLPSALPAMPSVPTVS---SLGGL-NFPWMESSRRFVK 136
                                PP     P  PS P      S+GGL   P        VK
Sbjct: 78  SALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLP----EDALVK 133

Query: 137 DRFTAAAALTPFTVTRRIGHPYQNRTPPK---------RKKPRTSFSRVQICELEKRFHR 187
                    TP+  + R   P   R  P           +KPRT F+  Q+  LE++F +
Sbjct: 134 AESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQ 193

Query: 188 QKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM 240
           ++YL+ AERA  + SL +T+ QVK WFQNRR K +R    E E  +  A  ++
Sbjct: 194 KQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPML 246


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 46/109 (42%), Positives = 64/109 (58%), Gaps = 12/109 (11%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
           K +K RT+FS  Q+ +LE+ F RQKYL+  +R  LA +L +TD QVKTW+QNRRTKW+RQ
Sbjct: 231 KPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290

Query: 225 TAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQN 273
           TA            + L+L  +A   S    + P P   H S L ++ +
Sbjct: 291 TA------------VGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDS 327


>gi|28912912 NK6 transcription factor related, locus 2 [Homo
           sapiens]
          Length = 277

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 43/74 (58%), Positives = 51/74 (68%), Gaps = 1/74 (1%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWR-R 223
           K+K  R +FS  QI  LEK F + KYLA  ERA LA SL MT++QVK WFQNRRTKWR R
Sbjct: 147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR 206

Query: 224 QTAEEREAERQQAS 237
             AE   A+++Q S
Sbjct: 207 HAAEMASAKKKQDS 220


>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
          Length = 290

 Score = 79.3 bits (194), Expect = 4e-15
 Identities = 71/246 (28%), Positives = 101/246 (41%), Gaps = 19/246 (7%)

Query: 3   APASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRP----GATYPS 58
           APA+A    P     F I+ ++            G  G+  L       P       YP 
Sbjct: 28  APAAATMFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPH 87

Query: 59  LPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVS 118
             A+ A   + F  A +     SL     +  P     P     P    L A P  P  S
Sbjct: 88  PSAAEAAFVSGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQ-LGASPLQPPHS 146

Query: 119 SLGGLN------FPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS 172
             G  +      +PW+  +R F   RF A+       +   +  P+      K K+ RT+
Sbjct: 147 FFGAQHRDPLHFYPWVLRNR-FFGHRFQASDVPQDGLL---LHGPFAR----KPKRIRTA 198

Query: 173 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAE 232
           FS  Q+  LE+ F +  Y+  AER  LA SL +++ QVK WFQNRRTK++RQ  EE   E
Sbjct: 199 FSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPE 258

Query: 233 RQQASR 238
            +Q  +
Sbjct: 259 SEQKKK 264


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 48/215 (22%)

Query: 12  PHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFE 71
           P +P S G   +   P Q + PAP+ P  A     PP   P A  P   AS      P +
Sbjct: 79  PSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQ---PPAPTPAAPPPPSSAS------PPQ 129

Query: 72  DAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESS 131
           +A +                         P P  +A   + + PTV+      FPWM+ S
Sbjct: 130 NASNN------------------------PTPANAAKSPLLNSPTVAKQ---IFPWMKES 162

Query: 132 RRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKR---KKPRTSFSRVQICELEKRFHRQ 188
           R+  K + +++++               +++PP +   K+ RT+++  Q+ ELEK FH  
Sbjct: 163 RQNTKQKTSSSSSGESCA---------GDKSPPGQASSKRARTAYTSAQLVELEKEFHFN 213

Query: 189 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRR 223
           +YL    R  +A  L +T+ Q+K WFQNRR K+++
Sbjct: 214 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 248


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 78.6 bits (192), Expect = 6e-15
 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 48/215 (22%)

Query: 12  PHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFE 71
           P +P S G   +   P Q + PAP+ P  A     PP   P A  P   AS      P +
Sbjct: 79  PSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQ---PPAPTPAAPPPPSSAS------PPQ 129

Query: 72  DAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESS 131
           +A +                         P P  +A   + + PTV+      FPWM+ S
Sbjct: 130 NASNN------------------------PTPANAAKSPLLNSPTVAKQ---IFPWMKES 162

Query: 132 RRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKR---KKPRTSFSRVQICELEKRFHRQ 188
           R+  K + +++++               +++PP +   K+ RT+++  Q+ ELEK FH  
Sbjct: 163 RQNTKQKTSSSSSGESCA---------GDKSPPGQASSKRARTAYTSAQLVELEKEFHFN 213

Query: 189 KYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRR 223
           +YL    R  +A  L +T+ Q+K WFQNRR K+++
Sbjct: 214 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 248


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 36/66 (54%), Positives = 48/66 (72%)

Query: 163 PPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWR 222
           P  R+KPR  FS+ Q+ ELE+RF +Q+YL++ ER  LA SLK+T  QVK WFQNRR K +
Sbjct: 145 PRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCK 204

Query: 223 RQTAEE 228
           RQ  ++
Sbjct: 205 RQRQDK 210


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 69/210 (32%), Positives = 93/210 (44%), Gaps = 26/210 (12%)

Query: 31  SAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRV 90
           +A A     G   LG  PGG  G     LPA  A  G P      YS     A A    +
Sbjct: 126 AAAAAAAAAGGLALGLHPGGAQGGA--GLPAQAALYGHPVY---GYS-----AAAAAAAL 175

Query: 91  PAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFP-WMESSRRFVKDRFTAAAALTPFT 149
               P      P +  A PA P+ P     G      W+ +S        TA   L    
Sbjct: 176 AGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRAS--------TAGMILPKMP 227

Query: 150 VTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQ 209
                    Q+    K ++PRT+F+  Q+ ELE +F   KYL+  +R  +A SL +T+ Q
Sbjct: 228 ---DFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQ 284

Query: 210 VKTWFQNRRTKWRR-QTAEE---REAERQQ 235
           VK WFQNRR KW+R + A+E   +EAE+Q+
Sbjct: 285 VKIWFQNRRMKWKRSKKAKEQAAQEAEKQK 314


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 39/81 (48%), Positives = 56/81 (69%), Gaps = 1/81 (1%)

Query: 164 PKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKW-R 222
           P++K+ R +FS  Q+ ELE+RF+ Q+YL+  ERA LA SLK+T+ QVK WFQNRR K  R
Sbjct: 204 PRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 263

Query: 223 RQTAEEREAERQQASRLMLQL 243
           RQ A +  A    A ++ +++
Sbjct: 264 RQMAADLLASAPAAKKVAVKV 284


>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 41/96 (42%), Positives = 63/96 (65%), Gaps = 2/96 (2%)

Query: 157 PYQNRTPPK-RKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQ 215
           P   +TP + +K+ R +FS  Q+ ELE++F  QKYL++ ERA LAK+LK+T+ QVK WFQ
Sbjct: 114 PRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQ 173

Query: 216 NRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKS 251
           NRR K +R+       + ++ S L   L+ +AF ++
Sbjct: 174 NRRYKTKRKQLSSELGDLEKHSSLP-ALKEEAFSRA 208


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 59/203 (29%), Positives = 80/203 (39%), Gaps = 37/203 (18%)

Query: 37  GPDGASYLGG--------PPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVI 88
           G  GA Y GG        PPG  P   +   P   +G G                P G  
Sbjct: 30  GEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHY 89

Query: 89  RVPAHR-PLPGAVPP-PLPSAL------PAMPSVPTVSSLGGLNFPWMESSRRFVKDRFT 140
             P    P P A PP PLP A       P  P   T      + +PWM+           
Sbjct: 90  AAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVH-------- 141

Query: 141 AAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALA 200
                        +     N T  + K+ RT+++R Q+ ELEK FH  +YL    R  +A
Sbjct: 142 -------------VNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIA 188

Query: 201 KSLKMTDAQVKTWFQNRRTKWRR 223
            +L +++ Q+K WFQNRR KW++
Sbjct: 189 HTLCLSERQIKIWFQNRRMKWKK 211


>gi|27886557 msh homeobox 2 [Homo sapiens]
          Length = 267

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 72/234 (30%), Positives = 105/234 (44%), Gaps = 44/234 (18%)

Query: 24  LNSPDQDSAPAPRGPDGASYLGGPPGGRPGAT------YPSLPASFAGLGA--------- 68
           L SPD++      GP      G  PGG  GA         SLP S   L +         
Sbjct: 10  LFSPDEEGPAVVAGP------GPGPGGAEGAAEERRVKVSSLPFSVEALMSDKKPPKEAS 63

Query: 69  --PFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFP 126
             P E A + +    L  +G     AH P  G +  P  +A     SV + +S  G    
Sbjct: 64  PLPAESASAGATLRPLLLSGHGAREAHSP--GPLVKPFETA-----SVKSENSEDGA--A 114

Query: 127 WMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFH 186
           WM+   R+          ++P T T R     +++T    +KPRT F+  Q+  LE++F 
Sbjct: 115 WMQEPGRYSPP----PRHMSPTTCTLR-----KHKT---NRKPRTPFTTSQLLALERKFR 162

Query: 187 RQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLM 240
           +++YL+ AERA  + SL +T+ QVK WFQNRR K +R    E E  +  A  ++
Sbjct: 163 QKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPML 216


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 82/282 (29%), Positives = 115/282 (40%), Gaps = 45/282 (15%)

Query: 10  PHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRP----GATYPSLPASFAG 65
           P P  P S G+      P       P+ PD +SY    P   P    GA +P+    +A 
Sbjct: 15  PGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAA 74

Query: 66  LGAPFEDAGSYS-VNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN 124
              P   A + S  +L+  P      P   P+P A P P P  L A P       LGG  
Sbjct: 75  AYGPGPAAPAASPASLAFGPP-----PDFSPVP-APPGPGPGLL-AQP-------LGGPG 120

Query: 125 FPWMESSRRFVKDRFTAAAALTPFTVTRRI------GHPYQNRTPPKRKKPRTSFSRVQI 178
            P    ++R            TP+   RR       G   + RT  K +   T   R+  
Sbjct: 121 TPSSPGAQR-----------PTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRL-- 167

Query: 179 CELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASR 238
            ELEK FH  +Y+    ++ LA +L +T+ QVK WFQNRR K R+      + ++QQ   
Sbjct: 168 -ELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERK----VNKKKQQQQQP 222

Query: 239 LMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEED 280
               + HD        S+    LC  N+SL A  +  P +E+
Sbjct: 223 PQPPMAHDITATPAGPSL--GGLCPSNTSLLATSSPMPVKEE 262


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 34/74 (45%), Positives = 51/74 (68%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
           K ++ RT+F+  Q+ ELEK FH +KYL+  ER+ +A +LK+++ QVK WFQNRR KW+R 
Sbjct: 246 KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRV 305

Query: 225 TAEEREAERQQASR 238
            A    ++  + SR
Sbjct: 306 KAGNANSKTGEPSR 319


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 46/142 (32%), Positives = 66/142 (46%), Gaps = 7/142 (4%)

Query: 91  PAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALT---- 146
           P   P  GA   P PS   +  S     +L    +PWM+  +   K     AAA      
Sbjct: 61  PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 120

Query: 147 ---PFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSL 203
              P  ++ +      + +    ++ RT+++  Q+ ELEK FH  KYL    R  +A  L
Sbjct: 121 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180

Query: 204 KMTDAQVKTWFQNRRTKWRRQT 225
            +T+ QVK WFQNRR K +RQT
Sbjct: 181 DLTERQVKVWFQNRRMKHKRQT 202


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 74.7 bits (182), Expect = 9e-14
 Identities = 34/64 (53%), Positives = 47/64 (73%)

Query: 165 KRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
           +R+KPR  FS+ Q+ ELE+RF +Q+YL++ ER  LA  LK+T  QVK WFQNRR K +RQ
Sbjct: 137 RRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQ 196

Query: 225 TAEE 228
             ++
Sbjct: 197 RQDQ 200


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,717,722
Number of Sequences: 37866
Number of extensions: 822588
Number of successful extensions: 9296
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 488
Number of HSP's that attempted gapping in prelim test: 5942
Number of HSP's gapped (non-prelim): 3022
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press