Guide to the Human Genome
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Search of human proteins with 50345997

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50345997 E1A binding protein p300 [Homo sapiens]
         (2414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50345997 E1A binding protein p300 [Homo sapiens]                  4983   0.0  
gi|119943104 CREB binding protein isoform a [Homo sapiens]           2797   0.0  
gi|119943102 CREB binding protein isoform b [Homo sapiens]           2697   0.0  
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...   106   3e-22
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...   106   3e-22
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]             101   8e-21
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    91   1e-17
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            91   1e-17
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  89   5e-17
gi|56549696 E1A binding protein p400 [Homo sapiens]                    88   1e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    86   3e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     86   6e-16
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               84   1e-15
gi|164419758 bromodomain containing 2 [Homo sapiens]                   83   3e-15
gi|4826806 bromodomain containing 2 [Homo sapiens]                     83   3e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    83   4e-15
gi|150170670 piccolo isoform 2 [Homo sapiens]                          81   1e-14
gi|150378539 piccolo isoform 1 [Homo sapiens]                          81   1e-14
gi|110347429 mediator complex subunit 12 [Homo sapiens]                80   2e-14
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       80   2e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          80   2e-14
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    80   2e-14
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    80   2e-14
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    80   2e-14
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    80   2e-14
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       79   5e-14
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    79   5e-14
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    79   5e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     79   7e-14
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     79   7e-14

>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 4983 bits (12926), Expect = 0.0
 Identities = 2414/2414 (100%), Positives = 2414/2414 (100%)

Query: 1    MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60
            MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD
Sbjct: 1    MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD 60

Query: 61   INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120
            INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS
Sbjct: 61   INQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINS 120

Query: 121  MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA 180
            MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA
Sbjct: 121  MVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAA 180

Query: 181  GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240
            GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ
Sbjct: 181  GNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQ 240

Query: 241  PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMP 300
            PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMP
Sbjct: 241  PLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMP 300

Query: 301  NMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360
            NMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE
Sbjct: 301  NMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGE 360

Query: 361  VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420
            VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA
Sbjct: 361  VRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA 420

Query: 421  GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480
            GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM
Sbjct: 421  GDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQM 480

Query: 481  PTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540
            PTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ
Sbjct: 481  PTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQ 540

Query: 541  NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600
            NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL
Sbjct: 541  NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAAL 600

Query: 601  KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660
            KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN
Sbjct: 601  KDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPN 660

Query: 661  AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720
            AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM
Sbjct: 661  AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720

Query: 721  AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780
            AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI
Sbjct: 721  AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780

Query: 781  PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP 840
            PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP
Sbjct: 781  PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP 840

Query: 841  TPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS 900
            TPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
Sbjct: 841  TPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS 900

Query: 901  LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSST 960
            LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSST
Sbjct: 901  LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSST 960

Query: 961  EVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK 1020
            EVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK
Sbjct: 961  EVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK 1020

Query: 1021 TEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVD 1080
            TEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVD
Sbjct: 1021 TEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVD 1080

Query: 1081 PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYK 1140
            PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYK
Sbjct: 1081 PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYK 1140

Query: 1141 YCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHF 1200
            YCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHF
Sbjct: 1141 YCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHF 1200

Query: 1201 CEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL 1260
            CEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL
Sbjct: 1201 CEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL 1260

Query: 1261 HHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE 1320
            HHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE
Sbjct: 1261 HHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRRQNHPESGE 1320

Query: 1321 VTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQE 1380
            VTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQE
Sbjct: 1321 VTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQE 1380

Query: 1381 YGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP 1440
            YGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP
Sbjct: 1381 YGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP 1440

Query: 1441 SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKE 1500
            SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKE
Sbjct: 1441 SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKE 1500

Query: 1501 LPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK 1560
            LPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK
Sbjct: 1501 LPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK 1560

Query: 1561 SSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP 1620
            SSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP
Sbjct: 1561 SSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP 1620

Query: 1621 CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR 1680
            CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR
Sbjct: 1621 CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR 1680

Query: 1681 WHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQ 1740
            WHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQ
Sbjct: 1681 WHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQ 1740

Query: 1741 SLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENK 1800
            SLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENK
Sbjct: 1741 SLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENK 1800

Query: 1801 CPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG 1860
            CPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG
Sbjct: 1801 CPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG 1860

Query: 1861 QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG 1920
            QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG
Sbjct: 1861 QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG 1920

Query: 1921 PPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHL 1980
            PPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHL
Sbjct: 1921 PPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHL 1980

Query: 1981 EPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040
            EPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP
Sbjct: 1981 EPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040

Query: 2041 LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI 2100
            LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI
Sbjct: 2041 LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI 2100

Query: 2101 PGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGG 2160
            PGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGG
Sbjct: 2101 PGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGG 2160

Query: 2161 MSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYP 2220
            MSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYP
Sbjct: 2161 MSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYP 2220

Query: 2221 PQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP 2280
            PQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP
Sbjct: 2221 PQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP 2280

Query: 2281 QQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHV 2340
            QQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHV
Sbjct: 2281 QQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHV 2340

Query: 2341 SPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNS 2400
            SPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNS
Sbjct: 2341 SPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNS 2400

Query: 2401 DLNSNLSQSTLDIH 2414
            DLNSNLSQSTLDIH
Sbjct: 2401 DLNSNLSQSTLDIH 2414


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 2797 bits (7251), Expect = 0.0
 Identities = 1523/2504 (60%), Positives = 1766/2504 (70%), Gaps = 220/2504 (8%)

Query: 1    MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
            MAEN+++ GPP+ KR KLSSP  SA+  D TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1    MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57

Query: 60   DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111
            ++         V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 58   NL---------VPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108

Query: 112  SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160
            S  +  +++M KSP++Q   ++P++      TSGP    +Q+         G+  S    
Sbjct: 109  SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168

Query: 161  PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN 209
               G    MNA  N   PG+L + +G  ++        QVMNGS+GA GRGR   M YP 
Sbjct: 169  SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT 228

Query: 210  PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265
            P M G++ ++L E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +
Sbjct: 229  PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM 288

Query: 266  GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS 325
            GA+G+  Q+ +K  + N+L  F  D K      +PNM Q         G+V   A   G 
Sbjct: 289  GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQT----SVGIVPTQAIATGP 344

Query: 326  GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385
               TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 345  ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401

Query: 386  KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNP-SSLG 444
            K+CQVAHCASSRQIISHWKNCTRHDCPVCLPLKNA DKRNQQ IL     G+ N   S+G
Sbjct: 402  KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVG 461

Query: 445  VGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMR 504
             GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ  TQ Q Q   QQ  QP Q+ Q MR
Sbjct: 462  TGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQMR 519

Query: 505  PMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMPT 558
             ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +PT
Sbjct: 520  TLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPT 579

Query: 559  AAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGD 618
            AA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEGD
Sbjct: 580  AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD 639

Query: 619  MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQP 678
            MYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   +      P P + Q 
Sbjct: 640  MYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQA 698

Query: 679  QPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPPL 733
            QP    NGPL  P           + R+    G+N F  MS+      Q P+ PR   P+
Sbjct: 699  QPVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPM 747

Query: 734  QHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNV 777
             H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS     
Sbjct: 748  NHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GA 805

Query: 778  TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPS 837
             ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH   P+P P+
Sbjct: 806  MSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPA 860

Query: 838  RTPTPHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQ 896
             T       PS+    PP  T P P  PT P+ P     Q   P P   P+   TQ    
Sbjct: 861  STAAGM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT 917

Query: 897  VQPSLPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNP 954
            VQ +  A  +  QPQ   QP S  +  +S   PT P+    P TPLSQ A SI+ +V  P
Sbjct: 918  VQAAAQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTP 975

Query: 955  PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC--------- 1005
             S +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED          
Sbjct: 976  SSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEE 1035

Query: 1006 ------KMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059
                  K E  E +E+  E+K E+KEEE+  S      S +P Q +KKIFKPEELRQALM
Sbjct: 1036 TDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALM 1095

Query: 1060 PTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVD 1119
            PTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQYQEPWQYVD
Sbjct: 1096 PTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVD 1155

Query: 1120 DIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYG 1179
            D+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EFSPQTLCCYG
Sbjct: 1156 DVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYG 1215

Query: 1180 KQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTL 1239
            KQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+QF K+KNDTL
Sbjct: 1216 KQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTL 1275

Query: 1240 DPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLG 1299
            DPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSAKRL +TRLG
Sbjct: 1276 DPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLG 1335

Query: 1300 TFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKA 1359
              LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+ESFPYRTKA
Sbjct: 1336 NHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKA 1395

Query: 1360 LFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILI 1419
            LFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLRTAVYHEILI
Sbjct: 1396 LFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILI 1455

Query: 1420 GYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERI 1479
            GYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKA +ERI
Sbjct: 1456 GYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERI 1515

Query: 1480 VHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENT-SNEST 1538
            +HDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERK+EE+T ++E+T
Sbjct: 1516 IHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETT 1575

Query: 1539 DVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVI 1598
            + ++GDSKNAKKKNNKKT+KNKSS+SR NKKKP MPNVSNDLSQKLYATMEKHKEVFFVI
Sbjct: 1576 EGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVI 1635

Query: 1599 RLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVEL 1658
             L AGP  N+LPPIVDPDPL+ CDLMDGRDAFLTLARDKH EFSSLRR++WST+CMLVEL
Sbjct: 1636 HLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVEL 1695

Query: 1659 HTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNN 1718
            HTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K GLGLDDE ++
Sbjct: 1696 HTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSS 1755

Query: 1719 QQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGG 1778
            Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGG
Sbjct: 1756 QGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGG 1815

Query: 1779 CPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRT 1838
            CP+CKQLIALCCYHAKHCQENKCPVPFCLNIK KLRQQQ+QHRLQQAQ++RRRMA+M   
Sbjct: 1816 CPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTR 1875

Query: 1839 GVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGP 1895
             V   QQ LPSPT A P TPT QQP+TPQTPQP +QPQP+P +  P   P + RTQ    
Sbjct: 1876 NV--PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTT 1932

Query: 1896 VSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
            VS GK   QV  P PP  AQ     PPPAAVE A QI+R A+ Q+ +  V      I + 
Sbjct: 1933 VSTGKPTSQV--PAPPPPAQ-----PPPAAVEAARQIEREAQQQQHLYRVN-----INNS 1980

Query: 1956 MPP-----MTP---MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQ 2007
            MPP      TP   MAP+ +N P   +  SG + P M P        W Q  LPQ QQ  
Sbjct: 1981 MPPGRTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPP------GQWQQAPLPQ-QQPM 2032

Query: 2008 SGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQ 2067
             G+PRP +   AQ       A   G     + P  P ++S  ALQ+LLRTL+SPSSP QQ
Sbjct: 2033 PGLPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQ 2083

Query: 2068 QQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSN 2127
            QQVL+IL +NPQL+AAFIKQR AKY  + P   P QPG+ Q QPG+QP     Q G+H  
Sbjct: 2084 QQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQ 2136

Query: 2128 PAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQ---MNMNHN----TMPSQFR 2180
            P++QN+N MQAGV R G+P   PQQQ    MGG++PQ Q    MN  HN    +M  Q+R
Sbjct: 2137 PSLQNLNAMQAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2190

Query: 2181 DILRR----------QQMMQQQQQQGAGPGIGPGMANHNQFQQPQGV-GYPP--QQQQRM 2227
            ++LRR          QQ  QQQQQQ    G+  GMA H QFQQPQG  GYPP  QQQQRM
Sbjct: 2191 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRM 2250

Query: 2228 QHH-------MQQM--QQGNMGQIGQLPQALGAEAGASL-QAYQQRLLQ-----QQMGSP 2272
            Q H       M QM  Q G +GQ+GQ    LGA++  ++ QA QQR+LQ     QQ+GSP
Sbjct: 2251 QQHLPLQGSSMGQMAAQMGQLGQMGQ--PGLGADSTPNIQQALQQRILQQQQMKQQIGSP 2308

Query: 2273 VQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQ 2332
             QPNPMSPQQHML  Q Q+ HL GQQI  SLSNQVRSP PV SPRPQSQPPHSSPSPR+Q
Sbjct: 2309 GQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQ 2368

Query: 2333 PQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQL 2376
            PQPSPHHVSPQT SPHPGL    A+ ++QGH  +P+Q++ML QL
Sbjct: 2369 PQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 2412



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 66/283 (23%), Positives = 99/283 (34%), Gaps = 43/283 (15%)

Query: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869
            +Q L+QQQ Q + QQ Q  +++ ++    G+ G  Q               QQP  P   
Sbjct: 2195 RQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQF--------------QQPQGPGGY 2240

Query: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMA 1929
             P  Q Q      M  +LP         QG + GQ+      Q  Q    G P    +  
Sbjct: 2241 PPAMQQQ----QRMQQHLPL--------QGSSMGQMAA----QMGQLGQMGQPGLGADST 2284

Query: 1930 MQIQRAAETQRQMAHVQIFQRPIQHQMP-PMTPMAPMGMNPPPMTRGPSGHLEPGMG--- 1985
              IQ+A + QR +   Q+ Q+      P PM+P   M    P  +  P   +   +    
Sbjct: 2285 PNIQQALQ-QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV 2343

Query: 1986 --PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKP 2043
              P  +Q   P SQ     P       P P       H  P   +P PGL     S +  
Sbjct: 2344 RSPAPVQSPRPQSQPPHSSPSPRIQPQPSP------HHVSPQTGSPHPGLAVTMASSIDQ 2397

Query: 2044 GTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIK 2086
            G +       +L  L +PS      ++  +       L  F++
Sbjct: 2398 GHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2440


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 2697 bits (6990), Expect = 0.0
 Identities = 1486/2505 (59%), Positives = 1731/2505 (69%), Gaps = 260/2505 (10%)

Query: 1    MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59
            MAEN+++ GPP+ KR KLSSP  SA+  D TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1    MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57

Query: 60   DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111
            ++         V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 58   NL---------VPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108

Query: 112  SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160
            S  +  +++M KSP++Q   ++P++      TSGP    +Q+         G+  S    
Sbjct: 109  SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168

Query: 161  PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN 209
               G    MNA  N   PG+L + +G  ++        QVMNGS+GA GRGR   M YP 
Sbjct: 169  SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT 228

Query: 210  PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265
            P M G++ ++L E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +
Sbjct: 229  PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM 288

Query: 266  GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS 325
            GA+G+  Q+ +K  + N+L  F  D K      +PNM Q         G+V   A   G 
Sbjct: 289  GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQT----SVGIVPTQAIATGP 344

Query: 326  GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385
               TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 345  ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401

Query: 386  KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL 443
            K+CQ                                        + G+P  G+ N   S+
Sbjct: 402  KACQA---------------------------------------ILGSPASGIQNTIGSV 422

Query: 444  GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM 503
            G GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ  TQ Q Q   QQ  QP Q+ Q M
Sbjct: 423  GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM 480

Query: 504  RPMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP 557
            R ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +P
Sbjct: 481  RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP 540

Query: 558  TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 617
            TAA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEG
Sbjct: 541  TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 600

Query: 618  DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ 677
            DMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   +      P P + Q
Sbjct: 601  DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ 659

Query: 678  PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPP 732
             QP    NGPL  P           + R+    G+N F  MS+      Q P+ PR   P
Sbjct: 660  AQPVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASP 708

Query: 733  LQHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMN 776
            + H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS    
Sbjct: 709  MNHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-G 766

Query: 777  VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVP 836
              ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH   P+P P
Sbjct: 767  AMSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPP 821

Query: 837  SRTPTPHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQ 895
            + T       PS+    PP  T P P  PT P+ P     Q   P P   P+   TQ   
Sbjct: 822  ASTAAGM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 878

Query: 896  QVQPSLPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSN 953
             VQ +  A  +  QPQ   QP S  +  +S   PT P+    P TPLSQ A SI+ +V  
Sbjct: 879  TVQAAAQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPT 936

Query: 954  PPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC-------- 1005
            P S +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED         
Sbjct: 937  PSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE 996

Query: 1006 -------KMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQAL 1058
                   K E  E +E+  E+K E+KEEE+  S      S +P Q +KKIFKPEELRQAL
Sbjct: 997  ETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1056

Query: 1059 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYV 1118
            MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQYQEPWQYV
Sbjct: 1057 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 1116

Query: 1119 DDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCY 1178
            DD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EFSPQTLCCY
Sbjct: 1117 DDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 1176

Query: 1179 GKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDT 1238
            GKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+QF K+KNDT
Sbjct: 1177 GKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDT 1236

Query: 1239 LDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRL 1298
            LDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSAKRL +TRL
Sbjct: 1237 LDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRL 1296

Query: 1299 GTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTK 1358
            G  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+ESFPYRTK
Sbjct: 1297 GNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTK 1356

Query: 1359 ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEIL 1418
            ALFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLRTAVYHEIL
Sbjct: 1357 ALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEIL 1416

Query: 1419 IGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSER 1478
            IGYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKA +ER
Sbjct: 1417 IGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAER 1476

Query: 1479 IVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENT-SNES 1537
            I+HDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERK+EE+T ++E+
Sbjct: 1477 IIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASET 1536

Query: 1538 TDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFV 1597
            T+ ++GDSKNAKKKNNKKT+KNKSS+SR NKKKP MPNVSNDLSQKLYATMEKHKEVFFV
Sbjct: 1537 TEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFV 1596

Query: 1598 IRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVE 1657
            I L AGP  N+LPPIVDPDPL+ CDLMDGRDAFLTLARDKH EFSSLRR++WST+CMLVE
Sbjct: 1597 IHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVE 1656

Query: 1658 LHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN 1717
            LHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K GLGLDDE +
Sbjct: 1657 LHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGS 1716

Query: 1718 NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG 1777
            +Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG
Sbjct: 1717 SQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG 1776

Query: 1778 GCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQR 1837
            GCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK KLRQQQ+QHRLQQAQ++RRRMA+M  
Sbjct: 1777 GCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNT 1836

Query: 1838 TGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAG 1894
              V   QQ LPSPT A P TPT QQP+TPQTPQP +QPQP+P +  P   P + RTQ   
Sbjct: 1837 RNV--PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893

Query: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH 1954
             VS GK   QV  P PP  AQ     PPPAAVE A QI+R A+ Q+ +  V      I +
Sbjct: 1894 TVSTGKPTSQV--PAPPPPAQ-----PPPAAVEAARQIEREAQQQQHLYRVN-----INN 1941

Query: 1955 QMPP-----MTP---MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQL 2006
             MPP      TP   MAP+ +N P   +  SG + P M P        W Q  LPQ QQ 
Sbjct: 1942 SMPPGRTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPP------GQWQQAPLPQ-QQP 1993

Query: 2007 QSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQ 2066
              G+PRP +   AQ       A   G     + P  P ++S  ALQ+LLRTL+SPSSP Q
Sbjct: 1994 MPGLPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQ 2044

Query: 2067 QQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHS 2126
            QQQVL+IL +NPQL+AAFIKQR AKY  + P   P QPG+ Q QPG+QP     Q G+H 
Sbjct: 2045 QQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQ 2097

Query: 2127 NPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQ---MNMNHN----TMPSQF 2179
             P++QN+N MQAGV R G+P   PQQQ    MGG++PQ Q    MN  HN    +M  Q+
Sbjct: 2098 QPSLQNLNAMQAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQY 2151

Query: 2180 RDILRR----------QQMMQQQQQQGAGPGIGPGMANHNQFQQPQGV-GYPP--QQQQR 2226
            R++LRR          QQ  QQQQQQ    G+  GMA H QFQQPQG  GYPP  QQQQR
Sbjct: 2152 REMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQR 2211

Query: 2227 MQHH-------MQQM--QQGNMGQIGQLPQALGAEAGASL-QAYQQRLLQ-----QQMGS 2271
            MQ H       M QM  Q G +GQ+GQ    LGA++  ++ QA QQR+LQ     QQ+GS
Sbjct: 2212 MQQHLPLQGSSMGQMAAQMGQLGQMGQ--PGLGADSTPNIQQALQQRILQQQQMKQQIGS 2269

Query: 2272 PVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRM 2331
            P QPNPMSPQQHML  Q Q+ HL GQQI  SLSNQVRSP PV SPRPQSQPPHSSPSPR+
Sbjct: 2270 PGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRI 2329

Query: 2332 QPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQL 2376
            QPQPSPHHVSPQT SPHPGL    A+ ++QGH  +P+Q++ML QL
Sbjct: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 2374



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 66/283 (23%), Positives = 99/283 (34%), Gaps = 43/283 (15%)

Query: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869
            +Q L+QQQ Q + QQ Q  +++ ++    G+ G  Q               QQP  P   
Sbjct: 2157 RQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQF--------------QQPQGPGGY 2202

Query: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMA 1929
             P  Q Q      M  +LP         QG + GQ+      Q  Q    G P    +  
Sbjct: 2203 PPAMQQQ----QRMQQHLPL--------QGSSMGQMAA----QMGQLGQMGQPGLGADST 2246

Query: 1930 MQIQRAAETQRQMAHVQIFQRPIQHQMP-PMTPMAPMGMNPPPMTRGPSGHLEPGMG--- 1985
              IQ+A + QR +   Q+ Q+      P PM+P   M    P  +  P   +   +    
Sbjct: 2247 PNIQQALQ-QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV 2305

Query: 1986 --PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKP 2043
              P  +Q   P SQ     P       P P       H  P   +P PGL     S +  
Sbjct: 2306 RSPAPVQSPRPQSQPPHSSPSPRIQPQPSP------HHVSPQTGSPHPGLAVTMASSIDQ 2359

Query: 2044 GTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIK 2086
            G +       +L  L +PS      ++  +       L  F++
Sbjct: 2360 GHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2402


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
            sapiens]
          Length = 722

 Score =  106 bits (264), Expect = 3e-22
 Identities = 80/273 (29%), Positives = 122/273 (44%), Gaps = 20/273 (7%)

Query: 880  PPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939
            P   Q  TPP TQ PQ   P + A P        P    +    V TP   ++PPQP   
Sbjct: 197  PNTTQASTPPQTQTPQPNPPPVQATP-------HPFPAVTPDLIVQTPVMTVVPPQPLQ- 248

Query: 940  LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999
             + P V  + Q    P+    + +   IA      + K   K + D   P    P  I E
Sbjct: 249  -TPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP--IHE 305

Query: 1000 SKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059
                  + ++T+  +R    +     ++D P +   Q  PAP +S K      E  +   
Sbjct: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS---QQHPAPEKSSKV----SEQLKCCS 358

Query: 1060 PTLEALYRQDPESL--PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQY 1117
              L+ ++ +   +   PF +PVD + LG+ DY DI+K PMD+STIK KL+  +Y++  ++
Sbjct: 359  GILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEF 418

Query: 1118 VDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFE 1150
              D+ LMF+N + YN     V     KL +VFE
Sbjct: 419  GADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 451



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 47/163 (28%), Positives = 86/163 (52%), Gaps = 12/163 (7%)

Query: 1016 STELKTEIKEEEDQPSTSATQSSPAPGQSK--KKIFKPEELRQALMPTLEALYRQDPESL 1073
            ++++ T   + + QP+ +A+ + P P  S   K   +  +L+  L   L+ L++    + 
Sbjct: 23   TSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQ-FAW 81

Query: 1074 PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNR 1133
            PF+QPVD   L +PDY+ I+K+PMD+ TIK++L+   Y    + + D   MF N ++YN+
Sbjct: 82   PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK 141

Query: 1134 KTSRVYKYCSKLSEVFEQEIDP---------VMQSLGYCCGRK 1167
                +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 142  PGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 48/165 (29%), Positives = 66/165 (40%), Gaps = 39/165 (23%)

Query: 823 PQPALHQNSPSPVPSRTPTPHHTP---PSIGAQQPPATTIPA-PVPTPPAMPPGPQSQAL 878
           PQ    Q +P PV +   TPH  P   P +  Q P  T +P  P+ TPP +PP PQ    
Sbjct: 206 PQTQTPQPNPPPVQA---TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQ---- 258

Query: 879 HPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA-------PL 931
                    PP    PQ VQ   P   +  QP +  +  +  A +  TPT        P 
Sbjct: 259 ---------PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT-TPTTIDPIHEPPS 308

Query: 932 LPPQPAT-----------PLSQPAVSIEGQVSNPPSTSSTEVNSQ 965
           LPP+P T           P+  P   +     +P    S++V+ Q
Sbjct: 309 LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)

Query: 741 QPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSS 800
           + G   P +   P   Q S      PQTQ P            P   QA        +  
Sbjct: 185 ETGTAKPGVSTVPNTTQASTP----PQTQTPQPN---------PPPVQATPHPFPAVTPD 231

Query: 801 CPVNSPIM---PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857
             V +P+M   PP          Q P P   Q  P P P+  P   H PP I A   P  
Sbjct: 232 LIVQTPVMTVVPPQPL-------QTPPPVPPQPQPPPAPAPQPVQSH-PPIIAATPQPVK 283

Query: 858 T-----IPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA-APSADQP- 910
           T       A   TP  + P      +H PP   P P TT+L Q+ + S P   P  D P 
Sbjct: 284 TKKGVKRKADTTTPTTIDP------IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337

Query: 911 -QQQPRSQQSTAAS 923
            QQ P  ++S+  S
Sbjct: 338 SQQHPAPEKSSKVS 351



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 5/77 (6%)

Query: 1852 PATPTTPTGQQPTTP---QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQ--GKAAGQVT 1906
            P   T P   Q +TP   QTPQP   P    P+  P   P      PV         Q  
Sbjct: 191  PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250

Query: 1907 PPTPPQTAQPPLPGPPP 1923
            PP PPQ   PP P P P
Sbjct: 251  PPVPPQPQPPPAPAPQP 267



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 28/103 (27%), Positives = 35/103 (33%), Gaps = 16/103 (15%)

Query: 1845 QGLPSPTPAT--------------PTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRT 1890
            Q  P P PA               P  P    P  P  PQP   P P P  S PP +  T
Sbjct: 219  QATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAAT 278

Query: 1891 QAAGPVSQG--KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931
                   +G  + A   TP T     +PP   P P   ++  +
Sbjct: 279  PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQR 321



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 16/149 (10%)

Query: 904  APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
            A   D+P++   +  S A  VP PT  + PP      S  + S     S+  +  S E  
Sbjct: 455  AKMPDEPEEPVVAVSSPA--VPPPTKVVAPPS-----SSDSSSDSSSDSDSSTDDSEEER 507

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +Q +AE Q   +   E    + QP+    +P+   + K E  K +    EE     K++ 
Sbjct: 508  AQRLAELQEQLKAVHEQLAALSQPQ--QNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565

Query: 1024 KE-------EEDQPSTSATQSSPAPGQSK 1045
            KE       + +  +++ ++  PAP +SK
Sbjct: 566  KEPPPKKTKKNNSSNSNVSKKEPAPMKSK 594



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 13/169 (7%)

Query: 861  APVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ--- 917
            A +P  P  P    S    PPP +   PP++        S   + S+    ++ R+Q   
Sbjct: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSS--DSSSDSSSDSDSSTDDSEEERAQRLA 512

Query: 918  --QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
              Q    +V    A L  PQ   P  +     E +          E N ++ A++ P ++
Sbjct: 513  ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKK 572

Query: 976  VK----MEAKMEVDQPEPADTQPEDISESKVED-CKMESTETEERSTEL 1019
             K      + +   +P P  ++P    ES+ ED CK  S E E+R   L
Sbjct: 573  TKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE-EKRQLSL 620



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 2275 PNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP-QPVPSPRPQSQPPHSSPSPRMQP 2333
            P   +PQ +  P QA +PH      P+ +   V++P   V  P+P   PP   P P  QP
Sbjct: 206  PQTQTPQPNPPPVQA-TPHPFPAVTPDLI---VQTPVMTVVPPQPLQTPPPVPPQP--QP 259

Query: 2334 QPSPHHVSPQTSSPHPGLVAAQANPME 2360
             P+P   +PQ    HP ++AA   P++
Sbjct: 260  PPAP---APQPVQSHPPIIAATPQPVK 283



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 11/142 (7%)

Query: 933  PPQPATPLSQPAVSIEGQVSNPPST--SSTEVNSQAIAEKQPSQEVKMEAKME------- 983
            P +P   +S PAV    +V  PPS+  SS++ +S + +    S+E + +   E       
Sbjct: 461  PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKA 520

Query: 984  VDQPEPADTQPEDISESKVE-DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042
            V +   A +QP+     K E D K +  E  +R  E++   K +  +P    T+ + +  
Sbjct: 521  VHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580

Query: 1043 QSKKKIFKPEELRQALMPTLEA 1064
             +  K  +P  ++    PT E+
Sbjct: 581  SNVSK-KEPAPMKSKPPPTYES 601



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 1518 KELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKP 1571
            K+ E++++E+K+E++   E  +  K     AK+   KKT KN SS S  +KK+P
Sbjct: 537  KKKEKDKKEKKKEKHKRKEEVEENK--KSKAKEPPPKKTKKNNSSNSNVSKKEP 588



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 2274 QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQP 2333
            QPNP   Q    P  A +P L    I  +    V  PQP+ +P P   PP   P P   P
Sbjct: 212  QPNPPPVQATPHPFPAVTPDL----IVQTPVMTVVPPQPLQTPPPV--PPQPQPPPAPAP 265

Query: 2334 QPSPHHVSPQTSSPHP 2349
            QP   H     ++P P
Sbjct: 266  QPVQSHPPIIAATPQP 281


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score =  106 bits (264), Expect = 3e-22
 Identities = 80/273 (29%), Positives = 122/273 (44%), Gaps = 20/273 (7%)

Query: 880  PPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939
            P   Q  TPP TQ PQ   P + A P        P    +    V TP   ++PPQP   
Sbjct: 197  PNTTQASTPPQTQTPQPNPPPVQATP-------HPFPAVTPDLIVQTPVMTVVPPQPLQ- 248

Query: 940  LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999
             + P V  + Q    P+    + +   IA      + K   K + D   P    P  I E
Sbjct: 249  -TPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP--IHE 305

Query: 1000 SKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059
                  + ++T+  +R    +     ++D P +   Q  PAP +S K      E  +   
Sbjct: 306  PPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS---QQHPAPEKSSKV----SEQLKCCS 358

Query: 1060 PTLEALYRQDPESL--PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQY 1117
              L+ ++ +   +   PF +PVD + LG+ DY DI+K PMD+STIK KL+  +Y++  ++
Sbjct: 359  GILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEF 418

Query: 1118 VDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFE 1150
              D+ LMF+N + YN     V     KL +VFE
Sbjct: 419  GADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 451



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 119/508 (23%), Positives = 176/508 (34%), Gaps = 95/508 (18%)

Query: 1867 QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAV 1926
            Q P P  Q  P PP   PP                     PP P Q  QPP P PPP+  
Sbjct: 748  QAPAPVPQQPPPPPQQPPP---------------------PPPPQQQQQPPPPPPPPSMP 786

Query: 1927 EMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
            + A    +++        V     P+     P +   P+G    P+   P   L P +  
Sbjct: 787  QQAAPAMKSSPPPFIATQV-----PVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQ 841

Query: 1987 TGMQQQPPW-SQGGLPQPQQLQSGMP----RPAMMSVAQHGQPLNM-APQPGLGQVGISP 2040
                  PP  +Q  +  P  L + +P    RP+  + A   +P    A  P L Q   +P
Sbjct: 842  PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQ---TP 898

Query: 2041 LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI 2100
            L P     Q  Q LL     P+ PL   Q+   L    ++        + K  +  P P+
Sbjct: 899  LLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL 958

Query: 2101 PGQPGMP-----QGQPGLQPPTMPG---QQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQ 2152
            P  P        Q QP   PP  P    QQ     P   ++ PMQ        P  Q QQ
Sbjct: 959  PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018

Query: 2153 QLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGI-----GPGMAN 2207
               PP G   P  Q         P++ + +++     +  +      G       P M +
Sbjct: 1019 PPHPPPGQQPPPPQ---------PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH 1069

Query: 2208 HNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQ 2267
              Q  Q Q + +    QQ +Q   Q+++  ++ Q    PQ L              + ++
Sbjct: 1070 SPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQ----PQPLVV------------VKEE 1113

Query: 2268 QMGSPV-QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQ-----------PVPS 2315
            ++ SP+ +  P SP     P +           P S+   V  PQ           PV  
Sbjct: 1114 KIHSPIIRSEPFSPSLRPEPPKH----------PESIKAPVHLPQRPEMKPVDVGRPVIR 1163

Query: 2316 PRPQSQPPHSSPSPRMQPQPSPHHVSPQ 2343
            P  Q+ PP  +P    Q Q     V+P+
Sbjct: 1164 PPEQNAPPPGAPDKDKQKQEPKTPVAPK 1191



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 130/573 (22%), Positives = 185/573 (32%), Gaps = 109/573 (19%)

Query: 1843 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            Q Q  P+P P  P  P  Q P  P   Q    P P PP SMP      Q A P  +    
Sbjct: 745  QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP------QQAAPAMKSSPP 798

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH----QMPP 1958
              +    P    +P LPG                     + H   F +PI H    ++PP
Sbjct: 799  PFIATQVP--VLEPQLPG----------------SVFDPIGH---FTQPILHLPQPELPP 837

Query: 1959 MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSV 2018
              P  P    PP + +                  PP     LPQ         RP+  + 
Sbjct: 838  HLPQPPEHSTPPHLNQ-------------HAVVSPPALHNALPQQPS------RPSNRAA 878

Query: 2019 AQHGQPLN-MAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
            A   +P    A  P L Q   +PL P     Q  Q LL     P+ PL   Q+   L   
Sbjct: 879  ALPPKPARPPAVSPALTQ---TPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQL 935

Query: 2078 PQLLAAFIKQRAAKYANSNPQPIPGQP-----GMPQGQPGLQPPTM---PGQQGVHSNPA 2129
             ++        + K  +  P P+P  P        Q QP   PP     P QQ     P 
Sbjct: 936  QKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995

Query: 2130 MQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMM 2189
              ++ PMQ        P  Q QQ   PP G   P  Q                 + QQ++
Sbjct: 996  PVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP---------------AKPQQVI 1040

Query: 2190 QQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQAL 2249
            Q                 H++   P   G+  +    +  H  QM Q         PQ  
Sbjct: 1041 QHHHS-----------PRHHK-SDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ-- 1086

Query: 2250 GAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRS 2309
                    Q  Q +  + +  S VQP P+   +     +  SP ++ +    SL      
Sbjct: 1087 --------QNVQPKKQELRAASVVQPQPLVVVKE---EKIHSPIIRSEPFSPSL-----R 1130

Query: 2310 PQPVPSPRPQSQPPHSSPSPRMQPQPSPHHV--SPQTSSPHPGLVAAQANPMEQGHFASP 2367
            P+P   P     P H    P M+P      V   P+ ++P PG         E     +P
Sbjct: 1131 PEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190

Query: 2368 DQNSMLSQLASNPGMANLHGASATDLGLSTDNS 2400
             ++  +  + S   +   H  + +    S+ +S
Sbjct: 1191 KKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDS 1223



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 47/163 (28%), Positives = 86/163 (52%), Gaps = 12/163 (7%)

Query: 1016 STELKTEIKEEEDQPSTSATQSSPAPGQSK--KKIFKPEELRQALMPTLEALYRQDPESL 1073
            ++++ T   + + QP+ +A+ + P P  S   K   +  +L+  L   L+ L++    + 
Sbjct: 23   TSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQ-FAW 81

Query: 1074 PFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNR 1133
            PF+QPVD   L +PDY+ I+K+PMD+ TIK++L+   Y    + + D   MF N ++YN+
Sbjct: 82   PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK 141

Query: 1134 KTSRVYKYCSKLSEVFEQEIDP---------VMQSLGYCCGRK 1167
                +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 142  PGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 114/478 (23%), Positives = 162/478 (33%), Gaps = 70/478 (14%)

Query: 646  EKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNG----PLPDPSMIRGSVPNQ 701
            E+++        +  A   VP    P P    P P          P P PSM + + P  
Sbjct: 734  EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAM 793

Query: 702  ----------MMPRITPQ------SGLNQFGQ--MSMAQPPIVPRQTPPLQHHG--QLAQ 741
                       +P + PQ        +  F Q  + + QP + P    P +H     L Q
Sbjct: 794  KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQ 853

Query: 742  PGALNPPMGYGPRMQQPS---NQGQFLPQ--TQFPSQGMNVTNIPLAPSSGQAPVSQAQM 796
               ++PP  +    QQPS   N+   LP    + P+    +T  PL P    A   Q  +
Sbjct: 854  HAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLL 913

Query: 797  SSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPA 856
                 P  +P +       ++   Q  QP         V S+ P P   PP    QQ   
Sbjct: 914  EDEEPP--APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQ 971

Query: 857  TTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRS 916
               P P P  P  PP  Q Q   PPPR     P  Q    +Q   P  P   QP   P  
Sbjct: 972  QQPPPPPPPQPQPPPQQQHQ---PPPRPVHLQP-MQFSTHIQQ--PPPPQGQQPPHPPPG 1025

Query: 917  QQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEV 976
            QQ              PPQPA P  Q  +    Q  + P    ++  S     + PS  +
Sbjct: 1026 QQPP------------PPQPAKP--QQVI----QHHHSPRHHKSDPYSTGHLREAPSPLM 1067

Query: 977  KMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTE------IKEEEDQP 1030
                +M   Q     + P+   + K ++ +  S    +    +K E      I+ E   P
Sbjct: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127

Query: 1031 STSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPD 1088
            S       P P +  + I  P  L Q   P ++ +    P   P  Q   P   G PD
Sbjct: 1128 SL-----RPEPPKHPESIKAPVHLPQ--RPEMKPVDVGRPVIRPPEQNAPPP--GAPD 1176



 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 93/426 (21%), Positives = 152/426 (35%), Gaps = 53/426 (12%)

Query: 1862 QPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG- 1920
            QP TP  P    Q QP PP   PP+        P  Q +   Q  PP PPQ   PP    
Sbjct: 939  QPPTPLLPSVKVQSQPPPPLPPPPH--------PSVQQQLQQQPPPPPPPQPQPPPQQQH 990

Query: 1921 -PPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGH 1979
             PPP  V +        +  +   H+Q    P Q Q PP  P  P    PPP    P   
Sbjct: 991  QPPPRPVHL--------QPMQFSTHIQQ-PPPPQGQQPPHPP--PGQQPPPPQPAKPQQV 1039

Query: 1980 LEPGMGPTGMQQQPPWSQGGLPQ-PQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVG- 2037
            ++    P    +  P+S G L + P  L    P+ +      H  P     QP   ++  
Sbjct: 1040 IQHHHSPRH-HKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRA 1098

Query: 2038 ---ISPLKPGTVSQQALQNLLRTLRS--------PSSPLQQQQVLSILHA--NPQLLAAF 2084
               + P     V ++ + + +  +RS        P  P   + + + +H    P++    
Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPI--IRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVD 1156

Query: 2085 IKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAG 2144
            + +   +    N  P    PG P      Q P  P       +  ++NM    + VQ+  
Sbjct: 1157 VGRPVIRPPEQNAPP----PGAPDKDKQKQEPKTP--VAPKKDLKIKNMGSWASLVQKHP 1210

Query: 2145 LPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGP--GIG 2202
                   +            A++       + +Q     + ++ ++Q++ +       + 
Sbjct: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALE 1270

Query: 2203 PGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQ 2262
                 H + ++ Q      QQQQR +   QQ QQ         PQA  ++  + L   QQ
Sbjct: 1271 QARRAHEEARRRQ----EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLD--QQ 1324

Query: 2263 RLLQQQ 2268
            R L ++
Sbjct: 1325 RELARK 1330



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 75/298 (25%), Positives = 109/298 (36%), Gaps = 28/298 (9%)

Query: 836  PSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQ 895
            P R    HH       QQ PA     P P P   PP P  Q    PP   P PP   +PQ
Sbjct: 731  PGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPP---PPPPPPSMPQ 787

Query: 896  QVQPSLPAAPSADQPQQQPRSQQSTAASVPTP----TAPLLP-PQPATPLSQPAVSIEGQ 950
            Q  P++ ++P      Q P  +     SV  P    T P+L  PQP  P   P +    +
Sbjct: 788  QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP---PHLPQPPE 844

Query: 951  VSNPPSTSS-TEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMES 1009
             S PP  +    V+  A+    P Q  +   +     P+PA  +P  +S +  +   +  
Sbjct: 845  HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA--RPPAVSPALTQTPLLPQ 902

Query: 1010 TETEERSTELKTEIKEEEDQPSTSATQS------------SPAPGQSKKKIFKPEELRQA 1057
                +   ++  E +E    P TS                +P     K +   P  L   
Sbjct: 903  PPMAQ-PPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP 961

Query: 1058 LMPTLEALYRQDPESLPFRQP-VDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEP 1114
              P+++   +Q P   P  QP   PQ    P    +   PM  ST  ++    Q Q+P
Sbjct: 962  PHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 92/407 (22%), Positives = 145/407 (35%), Gaps = 80/407 (19%)

Query: 677  QPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHH 736
            QP P +    P P PS ++  +  Q  P   PQ    Q       QPP  P    P+Q  
Sbjct: 953  QPPPPLP---PPPHPS-VQQQLQQQPPPPPPPQP---QPPPQQQHQPPPRPVHLQPMQFS 1005

Query: 737  GQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQM 796
              + QP    PP G  P    P  Q    PQ   P Q +   + P    S        + 
Sbjct: 1006 THIQQPP---PPQGQQPPHPPPGQQPP-PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061

Query: 797  SSSSCPVNSPIMPPGSQGSHIHCPQL----------------PQPAL---HQNSPSPV-- 835
            + S   ++SP M      +H   PQ                 PQP +    +   SP+  
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR 1121

Query: 836  -----PSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPT 890
                 PS  P P   P SI A        P  +P  P M P    + +  PP Q   PP 
Sbjct: 1122 SEPFSPSLRPEPPKHPESIKA--------PVHLPQRPEMKPVDVGRPVIRPPEQNAPPP- 1172

Query: 891  TQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPT----APLLPPQPATPLSQPAVS 946
                         AP  D+ +Q+P++  +    +        A L+   P TP S     
Sbjct: 1173 ------------GAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSS----- 1215

Query: 947  IEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVED-- 1004
                 +   S+ S E   +A  EK+  +E  ++A+ E  + E    + E +   + ED  
Sbjct: 1216 -----TAKSSSDSFEQFRRAAREKE-EREKALKAQAEHAEKEKERLRQERMRSREDEDAL 1269

Query: 1005 -----CKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKK 1046
                    E+   +E+  + + E ++++ Q + +   ++    QS +
Sbjct: 1270 EQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQ 1316



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 48/165 (29%), Positives = 66/165 (40%), Gaps = 39/165 (23%)

Query: 823 PQPALHQNSPSPVPSRTPTPHHTP---PSIGAQQPPATTIPA-PVPTPPAMPPGPQSQAL 878
           PQ    Q +P PV +   TPH  P   P +  Q P  T +P  P+ TPP +PP PQ    
Sbjct: 206 PQTQTPQPNPPPVQA---TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQ---- 258

Query: 879 HPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA-------PL 931
                    PP    PQ VQ   P   +  QP +  +  +  A +  TPT        P 
Sbjct: 259 ---------PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT-TPTTIDPIHEPPS 308

Query: 932 LPPQPAT-----------PLSQPAVSIEGQVSNPPSTSSTEVNSQ 965
           LPP+P T           P+  P   +     +P    S++V+ Q
Sbjct: 309 LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)

Query: 741 QPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSS 800
           + G   P +   P   Q S      PQTQ P            P   QA        +  
Sbjct: 185 ETGTAKPGVSTVPNTTQASTP----PQTQTPQPN---------PPPVQATPHPFPAVTPD 231

Query: 801 CPVNSPIM---PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857
             V +P+M   PP          Q P P   Q  P P P+  P   H PP I A   P  
Sbjct: 232 LIVQTPVMTVVPPQPL-------QTPPPVPPQPQPPPAPAPQPVQSH-PPIIAATPQPVK 283

Query: 858 T-----IPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA-APSADQP- 910
           T       A   TP  + P      +H PP   P P TT+L Q+ + S P   P  D P 
Sbjct: 284 TKKGVKRKADTTTPTTIDP------IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337

Query: 911 -QQQPRSQQSTAAS 923
            QQ P  ++S+  S
Sbjct: 338 SQQHPAPEKSSKVS 351



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 5/77 (6%)

Query: 1852 PATPTTPTGQQPTTP---QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQ--GKAAGQVT 1906
            P   T P   Q +TP   QTPQP   P    P+  P   P      PV         Q  
Sbjct: 191  PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250

Query: 1907 PPTPPQTAQPPLPGPPP 1923
            PP PPQ   PP P P P
Sbjct: 251  PPVPPQPQPPPAPAPQP 267



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 28/103 (27%), Positives = 35/103 (33%), Gaps = 16/103 (15%)

Query: 1845 QGLPSPTPAT--------------PTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRT 1890
            Q  P P PA               P  P    P  P  PQP   P P P  S PP +  T
Sbjct: 219  QATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAAT 278

Query: 1891 QAAGPVSQG--KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931
                   +G  + A   TP T     +PP   P P   ++  +
Sbjct: 279  PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQR 321



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 19/89 (21%)

Query: 2293 HLQGQQIPNSLSNQ----VRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPH 2348
            H Q QQ P  +  Q     + P P P P+ Q QPP   P P M     P   +P   S  
Sbjct: 743  HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM-----PQQAAPAMKSSP 797

Query: 2349 PGLVAAQANPMEQ----------GHFASP 2367
            P  +A Q   +E           GHF  P
Sbjct: 798  PPFIATQVPVLEPQLPGSVFDPIGHFTQP 826



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 16/149 (10%)

Query: 904  APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
            A   D+P++   +  S A  VP PT  + PP      S  + S     S+  +  S E  
Sbjct: 455  AKMPDEPEEPVVAVSSPA--VPPPTKVVAPPS-----SSDSSSDSSSDSDSSTDDSEEER 507

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +Q +AE Q   +   E    + QP+    +P+   + K E  K +    EE     K++ 
Sbjct: 508  AQRLAELQEQLKAVHEQLAALSQPQ--QNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565

Query: 1024 KE-------EEDQPSTSATQSSPAPGQSK 1045
            KE       + +  +++ ++  PAP +SK
Sbjct: 566  KEPPPKKTKKNNSSNSNVSKKEPAPMKSK 594



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 13/169 (7%)

Query: 861  APVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ--- 917
            A +P  P  P    S    PPP +   PP++        S   + S+    ++ R+Q   
Sbjct: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSS--DSSSDSSSDSDSSTDDSEEERAQRLA 512

Query: 918  --QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
              Q    +V    A L  PQ   P  +     E +          E N ++ A++ P ++
Sbjct: 513  ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKK 572

Query: 976  VK----MEAKMEVDQPEPADTQPEDISESKVED-CKMESTETEERSTEL 1019
             K      + +   +P P  ++P    ES+ ED CK  S E E+R   L
Sbjct: 573  TKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYE-EKRQLSL 620



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 2275 PNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP-QPVPSPRPQSQPPHSSPSPRMQP 2333
            P   +PQ +  P QA +PH      P+ +   V++P   V  P+P   PP   P P  QP
Sbjct: 206  PQTQTPQPNPPPVQA-TPHPFPAVTPDLI---VQTPVMTVVPPQPLQTPPPVPPQP--QP 259

Query: 2334 QPSPHHVSPQTSSPHPGLVAAQANPME 2360
             P+P   +PQ    HP ++AA   P++
Sbjct: 260  PPAP---APQPVQSHPPIIAATPQPVK 283



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 11/142 (7%)

Query: 933  PPQPATPLSQPAVSIEGQVSNPPST--SSTEVNSQAIAEKQPSQEVKMEAKME------- 983
            P +P   +S PAV    +V  PPS+  SS++ +S + +    S+E + +   E       
Sbjct: 461  PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKA 520

Query: 984  VDQPEPADTQPEDISESKVE-DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042
            V +   A +QP+     K E D K +  E  +R  E++   K +  +P    T+ + +  
Sbjct: 521  VHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580

Query: 1043 QSKKKIFKPEELRQALMPTLEA 1064
             +  K  +P  ++    PT E+
Sbjct: 581  SNVSK-KEPAPMKSKPPPTYES 601



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 1518 KELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKP 1571
            K+ E++++E+K+E++   E  +  K     AK+   KKT KN SS S  +KK+P
Sbjct: 537  KKKEKDKKEKKKEKHKRKEEVEENK--KSKAKEPPPKKTKKNNSSNSNVSKKEP 588



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 2274 QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQP 2333
            QPNP   Q    P  A +P L    I  +    V  PQP+ +P P   PP   P P   P
Sbjct: 212  QPNPPPVQATPHPFPAVTPDL----IVQTPVMTVVPPQPLQTPPPV--PPQPQPPPAPAP 265

Query: 2334 QPSPHHVSPQTSSPHP 2349
            QP   H     ++P P
Sbjct: 266  QPVQSHPPIIAATPQP 281



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 50/194 (25%), Positives = 68/194 (35%), Gaps = 29/194 (14%)

Query: 2207 NHNQFQQ-----PQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGAS---LQ 2258
            +H Q QQ     PQ    PPQQ        QQ Q         +PQ       +S     
Sbjct: 742  HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801

Query: 2259 AYQQRLLQQQMGSPV--------QPNPMSPQQHMLPNQAQSP------HLQGQQI--PNS 2302
            A Q  +L+ Q+   V        QP    PQ  + P+  Q P      HL    +  P +
Sbjct: 802  ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861

Query: 2303 LSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQG 2362
            L N +      PS R  + PP  +  P + P  +   + PQ     P  V      +E  
Sbjct: 862  LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL-----LEDE 916

Query: 2363 HFASPDQNSMLSQL 2376
               +P   SM  QL
Sbjct: 917  EPPAPPLTSMQMQL 930


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score =  101 bits (252), Expect = 8e-21
 Identities = 168/632 (26%), Positives = 218/632 (34%), Gaps = 119/632 (18%)

Query: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQT 1868
            ++Q+ +QQQ Q + QQ Q  +++   +Q       QQ  P             Q   PQ 
Sbjct: 260  LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQP-------------QGIRPQF 306

Query: 1869 PQPTSQPQPTPPNSMPPYL----PRTQAAGPVSQGKAAGQVTPPTPPQ----------TA 1914
              PT  P P   N +P       P   + G ++  +   +   P P Q          T 
Sbjct: 307  TAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATV 366

Query: 1915 QPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTR 1974
            Q P   PPP     + Q  +A     QM++   F  P    +       P  +  P +T 
Sbjct: 367  QTPSHPPPPYPFG-SQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTN 425

Query: 1975 -----GPSGHLE--PGMGPT---GMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG-- 2022
                  PS   +  P   PT     QQ  P      P PQ  Q  +  P    + Q G  
Sbjct: 426  KSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV 485

Query: 2023 ---------QPLNMAPQ---PGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV 2070
                     QP N  PQ   PGLG +    L PG  + QA  N +           Q QV
Sbjct: 486  PPNFMVMQQQPPNQGPQSLHPGLGGMP-KRLPPGFSAGQANPNFM-----------QGQV 533

Query: 2071 LSILHANPQLLAAFIKQRAAKYANSNPQPIPGQ-PGMPQGQPGLQ--PPTM--PGQQGVH 2125
             S     P    A   Q     AN N Q   GQ  G PQ Q  +   PP M  P   G+H
Sbjct: 534  PSTTATTPGNSGAPQLQ-----ANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH 588

Query: 2126 SNPAMQNMNPMQAGVQRA------GLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179
             N  M N     +GV +       G PQQ P  QL      + P   QM     T+  Q 
Sbjct: 589  GN--MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQN 646

Query: 2180 RDILRRQQMMQQQQQQGAGP--GIGPG------------------MANHNQFQQPQGVGY 2219
              IL R Q+M Q Q     P   +GP                   MA HNQ   PQG   
Sbjct: 647  PMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQG-QV 705

Query: 2220 PPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQ-PNPM 2278
              QQ   ++  M    QGN  Q     Q+      A +       +Q   G+ VQ    M
Sbjct: 706  LLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQM 762

Query: 2279 SPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPH 2338
            S Q  MLP Q    +   Q +   +  QV  P   P P P     H  P+       S  
Sbjct: 763  SGQ--MLPQQGPVNNSPSQVM--GIQGQVLRP---PGPSPHMAQQHGDPATTANNDVSLS 815

Query: 2339 HVSP-----QTSSPHPGLVAAQANPMEQGHFA 2365
             + P     QT+   P + A Q N     HF+
Sbjct: 816  QMMPDVSIQQTNMVPPHVQAMQGNSASGNHFS 847



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 146/579 (25%), Positives = 195/579 (33%), Gaps = 102/579 (17%)

Query: 1888 PRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQM----- 1942
            P     G +     A  + PP    ++    PGP P   E+  +  R A     M     
Sbjct: 166  PMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNP---ELQPRTPRPASQSDAMDPLLS 222

Query: 1943 -AHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLP 2001
              H+Q    P     PP  PM P+ +N   M       L+        QQQ    Q    
Sbjct: 223  GLHIQQQSHPSGSLAPPHHPMQPVSVN-RQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQ 281

Query: 2002 QPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTL--- 2058
            Q QQLQ+  P+       Q  +P   AP       G + L  G +     Q  L T+   
Sbjct: 282  QQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTAN 341

Query: 2059 ----RSP-SSPLQQQQVLSILHANPQLLAA-----------FIKQRAAKYANSNPQ-PIP 2101
                ++P   P+QQQ     L A P L              F  Q+A++   + PQ   P
Sbjct: 342  QGWKKAPLPGPMQQQ-----LQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP 396

Query: 2102 GQPGMP-----QGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL-- 2154
            GQ   P     QG P   P  +      + +PA  + +  Q G   +     Q QQQ+  
Sbjct: 397  GQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPA-SSPSSFQQGSPASSPTVNQTQQQMGP 455

Query: 2155 QPPMGGMSPQAQQMNMN---HNTMPSQFRDILRRQQMMQQQQQQG--------------A 2197
            +PP     PQ  Q  ++    N M  Q         M QQ   QG               
Sbjct: 456  RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL 515

Query: 2198 GPGIGPGMANHN--QFQQP--------------------------QGVGYPPQQQQRMQH 2229
             PG   G AN N  Q Q P                          QG G PPQ Q ++ H
Sbjct: 516  PPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAG-PPQNQMQVSH 574

Query: 2230 HMQQMQQGN-MGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQ 2288
                M Q + MG  G +       +G           Q Q G P Q   M   Q ++P+Q
Sbjct: 575  GPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQ--LMGMHQQIVPSQ 632

Query: 2289 AQSPHLQG---QQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTS 2345
             Q    QG    Q P  LS     PQ      P SQ    SP     P+       PQ  
Sbjct: 633  GQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMM 692

Query: 2346 SPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384
            +PH  ++  Q   + Q       QN M+ Q+ +N    N
Sbjct: 693  APHNQMMGPQGQVLLQ-------QNPMIEQIMTNQMQGN 724



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 143/602 (23%), Positives = 195/602 (32%), Gaps = 79/602 (13%)

Query: 1845 QGLPSPTPATPTTPTGQQPTTP------QTPQPTSQPQPTPPN--SMPPYLPRTQAAGPV 1896
            QG   P  +    P  QQ   P      Q   P   PQ   P    MP  LP   +AG  
Sbjct: 465  QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524

Query: 1897 SQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQI---QRAAETQRQMAHVQIFQRPIQ 1953
            +     GQV P T   T  P   G P       +Q    Q A   Q QM         + 
Sbjct: 525  NPNFMQGQV-PSTTATT--PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQ--------VS 573

Query: 1954 HQMPPMTPMAPMGM--NPPPMTRGPSG---------HLEPGMGPT----GMQQQPPWSQG 1998
            H  P M   + MG+  N      G SG           +P  GP     GM QQ   SQG
Sbjct: 574  HGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQG 633

Query: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTL 2058
             + Q QQ       P ++S AQ      M   P    +G SP +  T  +Q L      +
Sbjct: 634  QMVQ-QQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRM-TPPKQMLSQQGPQM 691

Query: 2059 RSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPG-QPGMPQGQPGLQPPT 2117
             +P + +   Q   +L  NP +      Q        N Q      PG  Q   G   P 
Sbjct: 692  MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRG-PTPN 750

Query: 2118 MPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQ-----MNMNH 2172
            M G     +      M P Q  V  +       Q Q+  P G     AQQ        N+
Sbjct: 751  MQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANN 810

Query: 2173 NTMPSQFR-DILRRQ--------QMMQQQQQQG---AGPGIG-----PGMANHNQFQQPQ 2215
            +   SQ   D+  +Q        Q MQ     G   +G G+       G  N NQ    Q
Sbjct: 811  DVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQ 870

Query: 2216 GVGYPPQQQQRMQHHM------QQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQM 2269
              G+P  +   +   +        +  G+ G   +       +        +++  QQ +
Sbjct: 871  NPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDL 930

Query: 2270 GSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNS---LSNQVRSPQPVPSPRPQSQPPHSS 2326
             +P    P   ++    +Q   P  QG  + NS   L      P   PS   + +P    
Sbjct: 931  NTP-DTRPAGLEE---ADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQM 986

Query: 2327 PSPRMQ---PQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMA 2383
            P   MQ   P P P    PQ   P        + P  Q       Q  M+  +  +P   
Sbjct: 987  PPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSV 1046

Query: 2384 NL 2385
             L
Sbjct: 1047 RL 1048



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 119/542 (21%), Positives = 191/542 (35%), Gaps = 115/542 (21%)

Query: 490  NQQNQQPGQSPQGMRPMSNMSASP--------MGVNGGVGVQTPSLLSDSMLHSAINSQN 541
            N  NQQ G S      +SNM   P        MG++  +    PS          +N QN
Sbjct: 590  NMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQI---VPSQGQMVQQQGTLNPQN 646

Query: 542  PMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD----P 597
            PM+   A +   G M                          +V+   Q + P+P     P
Sbjct: 647  PMILSRAQLMPQGQM--------------------------MVNPPSQNLGPSPQRMTPP 680

Query: 598  AALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNM 657
              +  ++   ++A   ++ G   +    +    + + E+I   Q +  +++     + N+
Sbjct: 681  KQMLSQQGPQMMAPHNQMMGPQGQVLLQQ----NPMIEQIMTNQMQGNKQQFNTQNQSNV 736

Query: 658  LPNAAGMVPVSMNPGPNM------------GQ--PQPGMTSNGPLP----DPSMIR--GS 697
            +P   G   +   P PNM            GQ  PQ G  +N P         ++R  G 
Sbjct: 737  MP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGP 793

Query: 698  VPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGAL--NPPMGYGPRM 755
             P+       P +  N    +S   P +  +QT  +  H Q  Q  +   N   G+G   
Sbjct: 794  SPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSF 853

Query: 756  QQPSN---QGQFLPQTQFPSQGMNVTNIPLAP----------SSGQAPVSQAQMSSSSCP 802
              P +    G  +   Q P   +N      +P          S+G   V+  Q ++++  
Sbjct: 854  NAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANK 913

Query: 803  VNSPIMPPGSQGSH--IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIP 860
                  P   + S   ++ P      L +    P+P           + G + P  +  P
Sbjct: 914  PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGI---NLDNSGPKLPEFSNRP 970

Query: 861  APVPTPPA-------MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQ 913
               P+ P        MPP    Q + PPP+     P  QLPQQ QP  P+ P + Q QQQ
Sbjct: 971  PGYPSQPVEQRPLQQMPP-QLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQ 1029

Query: 914  -------------PRS-QQSTAASVPTPTAPLLPPQPATPLSQPA-----VSIEGQVSNP 954
                         P+S +   + +V  P  PL P     P+ Q       VS++G  S P
Sbjct: 1030 QQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVP 1089

Query: 955  PS 956
            PS
Sbjct: 1090 PS 1091



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 97/384 (25%), Positives = 131/384 (34%), Gaps = 74/384 (19%)

Query: 2005 QLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSP 2064
            ++++G P  +   + +   P  +   PG G V  S + PG   +  LQ   RT R  S  
Sbjct: 160  RMEAGFPMASGPGIIRMNNPATVMIPPG-GNVSSSMMAPGPNPE--LQP--RTPRPASQS 214

Query: 2065 LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGV 2124
                 +LS LH   Q               S+P      P  P     +QP ++  Q   
Sbjct: 215  DAMDPLLSGLHIQQQ---------------SHPSGSLAPPHHP-----MQPVSVNRQMNP 254

Query: 2125 HSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILR 2184
             + P +Q     Q   Q+    QQQ QQQ            QQ+               R
Sbjct: 255  ANFPQLQQQQQQQQQQQQQQQQQQQQQQQ------------QQLQ-------------AR 289

Query: 2185 RQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQ-QMQQGNMGQI- 2242
              Q  QQQQ QG  P          QF  P  V  PP   Q     +Q    QG++G + 
Sbjct: 290  PPQQHQQQQPQGIRP----------QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMT 339

Query: 2243 ---GQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHM-----LPNQAQSPHL 2294
               G     L       LQA       Q    P  P P   QQ        P  +     
Sbjct: 340  ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQF 399

Query: 2295 QGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAA 2354
               Q+ +      R P P+  P   ++ P SSPS   Q  P+      QT     G    
Sbjct: 400  TAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQ-QMGPRPP 458

Query: 2355 QANPMEQGH---FASPDQNSMLSQ 2375
            Q NP+ QG     +SP +N M+ Q
Sbjct: 459  QNNPLPQGFQQPVSSPGRNPMVQQ 482



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 142/635 (22%), Positives = 199/635 (31%), Gaps = 129/635 (20%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQT-----------PQPTSQPQPTPPNSMPPYLPRTQA 1892
            Q  +PS T  TP      Q    Q            PQ   Q    PPN M P L     
Sbjct: 530  QGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH- 588

Query: 1893 AGPVSQGKAAGQVTPPTPPQTAQ-PPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951
             G ++  +A     P       Q  P  GPP   + M  QI  +     Q       Q P
Sbjct: 589  -GNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNP 647

Query: 1952 IQHQMPPMTPMAPMGMNPPPMTRGPSGH----------------LEPG---MGPTG---M 1989
            +      + P   M +NPP    GPS                  + P    MGP G   +
Sbjct: 648  MILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL 707

Query: 1990 QQQPPWSQ-------------------GGLPQPQQLQSGMPRPAMMS------------- 2017
            QQ P   Q                     +P P Q+  G P P M               
Sbjct: 708  QQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRG-PTPNMQGNMVQFTGQMSGQM 766

Query: 2018 VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQN--LLRTLRSPSSPLQQQQVLSILH 2075
            + Q G P+N +P   +G  G     PG     A Q+     T  +  S  Q    +SI  
Sbjct: 767  LPQQG-PVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQ 825

Query: 2076 ANPQLLAAFIKQRAAKYANSNP---------QPIPGQPGMPQGQPGLQPPTMPGQQGVHS 2126
             N  ++   ++      A+ N           P  G P   Q   G  P     +    +
Sbjct: 826  TN--MVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLT 883

Query: 2127 NPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQ 2186
            +P + N+          G+  +Q       P     P+ ++ +      P      L   
Sbjct: 884  SPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEA 943

Query: 2187 QMMQQQQQQG-----AGPGIGPGMANHNQFQQPQGVGYPPQQQ---QRMQHHMQQMQQGN 2238
                   +QG     +GP + P  +N       Q V   P QQ   Q MQH     Q   
Sbjct: 944  DQPPLPGEQGINLDNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQ 1002

Query: 2239 MGQIGQLPQALGAEAGASLQAYQQRLLQQQMGS-------------PVQPNPMSPQQHML 2285
                 QLPQ       +  Q+ QQ+  QQQM               PV  N   P+  + 
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLN 1062

Query: 2286 PNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTS 2345
            P+  + P  Q   +P  +S Q   P  VP            PSP  Q  P P +    ++
Sbjct: 1063 PDSQRMPMQQSGSVPVMVSLQ--GPASVP------------PSPDKQRMPMPVNTPLGSN 1108

Query: 2346 SPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNP 2380
            S       +  NP           +S L+++AS P
Sbjct: 1109 SRKMVYQESPQNP----------SSSPLAEMASLP 1133



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 89/338 (26%), Positives = 118/338 (34%), Gaps = 41/338 (12%)

Query: 657 MLPNAAGMVPVSMNPGPNMG-QPQ-PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQ 714
           M+P    +    M PGPN   QP+ P   S     DP +    +  Q  P     SG   
Sbjct: 183 MIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHP-----SGSLA 237

Query: 715 FGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFL----PQTQF 770
                M QP  V RQ  P  +  QL Q            + QQ   Q Q L    PQ   
Sbjct: 238 PPHHPM-QPVSVNRQMNPA-NFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 295

Query: 771 PSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGS--------HIHCPQL 822
             Q   +     AP+    P    Q+ S +      + PP +QGS              L
Sbjct: 296 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGA------LQPPPAQGSLGTMTANQGWKKAPL 349

Query: 823 PQPALHQNSPSPVPSRTPTPHHTPPS--IGAQQPPATTIPAPVPTPPAMPPGPQSQALHP 880
           P P   Q    P  +   TP H PP    G+QQ        P  + P     PQ ++L  
Sbjct: 350 PGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQG 409

Query: 881 PPRQTPTPPTTQLPQQVQPSLPAAPSADQ---PQQQPRSQQSTAASVPTPTA-PLLPPQP 936
            P + PTP   Q P     S  ++PS+ Q   P   P   Q+     P P     LP   
Sbjct: 410 GPSRVPTP--LQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGF 467

Query: 937 ATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQ 974
             P+S P  +   Q  N P       N   + ++ P+Q
Sbjct: 468 QQPVSSPGRNPMVQQGNVPP------NFMVMQQQPPNQ 499



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 222/1088 (20%), Positives = 347/1088 (31%), Gaps = 208/1088 (19%)

Query: 1    MAENVVEPGPPSAKRPKLSSPALSASASD-----------GTDFGSLFDLEHDLPDELIN 49
            ++ +++ PGP    +P+   PA  + A D               GSL    H +    +N
Sbjct: 190  VSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVN 249

Query: 50   STELGLTNGGDINQLQTSLGMVQDAASKHKQLSELLRSGSSP----------NLNMGVGG 99
              ++   N   + Q Q      Q    + +Q  +  +  + P           +      
Sbjct: 250  R-QMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA 308

Query: 100  PGQV--------MASQAQQSSPGLGLINSMVKSP-MTQAGLTSPNMGMGTSGPNQGPTQS 150
            P QV        + S A Q  P  G + +M  +    +A L  P      + P+    Q+
Sbjct: 309  PTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQT 368

Query: 151  TGMMNSPV---NQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQY 207
                  P    +Q A   +T      NPG   A   + +          G  R    +Q 
Sbjct: 369  PSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQG--------GPSRVPTPLQQ 420

Query: 208  PNPGMGSAGNLLTEPLQQGSP-------QMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQN 260
            P+    S  +  +   QQGSP       Q   Q G R PQ       NNP P G      
Sbjct: 421  PHLTNKSPASSPSS-FQQGSPASSPTVNQTQQQMGPRPPQ-------NNPLPQGFQ---- 468

Query: 261  PGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLV-TPV 319
              Q + + G    +Q       N+ P  M  +  P    PN G    PQ   PGL   P 
Sbjct: 469  --QPVSSPGRNPMVQ-----QGNVPPNFMVMQQQP----PNQG----PQSLHPGLGGMPK 513

Query: 320  AQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHM 379
                G  A  A+P   +            +    + QAN  V+          +N +   
Sbjct: 514  RLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQM--- 570

Query: 380  THCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAP-VGLG 438
                     QV+H   +               P  + +   G+  NQQ   +G P V L 
Sbjct: 571  ---------QVSHGPPNMMQ------------PSLMGIH--GNMNNQQAGTSGVPQVNLS 607

Query: 439  NPSSLGVGQQSAPN--LSTVSQIDPSSIERAYAALGL----PYQVNQMPTQPQVQAK-NQ 491
            N    G  QQ  P+  +    QI PS  +       L    P  +++    PQ Q   N 
Sbjct: 608  NMQ--GQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNP 665

Query: 492  QNQQPGQSPQGMRPMSNMSASP-----------MGVNGGVGVQTPSLLSDSMLHSAINSQ 540
             +Q  G SPQ M P   M +             MG  G V +Q   ++   M +    ++
Sbjct: 666  PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNK 725

Query: 541  NPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVH---KLVQAIFPTPDP 597
                ++N S    GP      P             T +++ ++V    ++   + P   P
Sbjct: 726  QQFNTQNQSNVMPGPAQIMRGP-------------TPNMQGNMVQFTGQMSGQMLPQQGP 772

Query: 598  AALKDRRMENLVA----------YARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEK 647
                  ++  +            +  +  GD   +ANN      ++ +            
Sbjct: 773  VNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPD------------ 820

Query: 648  RRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT 707
                +Q+ NM+P     +  +   G +      GM+ N P           PN       
Sbjct: 821  --VSIQQTNMVPPHVQAMQGNSASGNHFSGH--GMSFNAPF-------SGAPNGNQMSCG 869

Query: 708  PQSGLNQFGQMSMAQPPIVPRQTPPLQ--HHG---QLAQPGALNPPMGYGPRMQQPSNQG 762
               G      +++  P +V      +   H G   +     A  P     PR ++ S Q 
Sbjct: 870  QNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929

Query: 763  QFLPQTQ-----------FPS-QGMNVTNI-PLAPSSGQAPVSQAQMSSSSCPVNSPIMP 809
               P T+            P  QG+N+ N  P  P     P           P+    MP
Sbjct: 930  LNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQ--MP 987

Query: 810  PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA-PVPTPPA 868
            P     H+  P  PQP   Q  P     + P P   P S   QQ     +    +   P 
Sbjct: 988  PQLM-QHVAPP--PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPK 1044

Query: 869  MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPT 928
                P SQ +HPP R    P + ++P Q   S+P   S   P   P S       +P  T
Sbjct: 1045 SVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT 1103

Query: 929  -------APLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981
                     +    P  P S P   +    S P ++ S   +        PS  V  + +
Sbjct: 1104 PLGSNSRKMVYQESPQNPSSSPLAEM---ASLPEASGSEAPSVPGGPNNMPSHVVLPQNQ 1160

Query: 982  MEVDQPEP 989
            + +  P+P
Sbjct: 1161 LMMTGPKP 1168



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 113/506 (22%), Positives = 171/506 (33%), Gaps = 104/506 (20%)

Query: 1852 PATPTTPTGQQPTTPQTPQPTSQ--PQPTPPNSMP-PYLPRTQAAGPVSQGKAAGQVTPP 1908
            P  P+ P  Q+P     PQ      P P PP   P P LP+ Q                 
Sbjct: 971  PGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQ----------------- 1013

Query: 1909 TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMN 1968
                  QPP P  P        Q Q+  + Q+QM  +      +  Q  P +   P+  N
Sbjct: 1014 ------QPPPPSQP--------QSQQQQQQQQQMMMM------LMMQQDPKSVRLPVSQN 1053

Query: 1969 PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMA 2028
              P    P G L P       Q+ P    G +P    LQ     PA +  +   Q +   
Sbjct: 1054 VHP----PRGPLNP-----DSQRMPMQQSGSVPVMVSLQG----PASVPPSPDKQRM--- 1097

Query: 2029 PQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVL--------SILHANPQL 2080
            P P    +G +  K   V Q++ QN        SSPL +   L          +   P  
Sbjct: 1098 PMPVNTPLGSNSRK--MVYQESPQN------PSSSPLAEMASLPEASGSEAPSVPGGPNN 1149

Query: 2081 LAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP--TMPGQQGVH-SNPAMQNMNPMQ 2137
            + + +     +   + P+P P      QG    QPP  ++P   G H  N A        
Sbjct: 1150 MPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP 1209

Query: 2138 AGVQRAGLPQQQPQ------QQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQ 2191
                RA      PQ         +P    +SP+    ++     P     +  R  + + 
Sbjct: 1210 KTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRG 1269

Query: 2192 QQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGA 2251
              QQG  P     +      Q P  +   P      Q H       N G+         +
Sbjct: 1270 FDQQGLNPTTLKAIG-----QAPSNLTMNPSNFATPQTHKLDSVVVNSGK--------QS 1316

Query: 2252 EAGASLQAYQQRLLQQQMGSPVQPNPMSPQQH------MLPNQAQSPHLQGQQIPNSLSN 2305
             +GA+ +A      +   GS  +  P   +Q+       L +Q  +  LQ  ++P    N
Sbjct: 1317 NSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR---N 1373

Query: 2306 QVRSPQPVPSPR-PQSQPPHSSPSPR 2330
             + SP P+ +P  P S P +S  +P+
Sbjct: 1374 VLVSPTPLANPPVPGSFPNNSGLNPQ 1399



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 112/479 (23%), Positives = 159/479 (33%), Gaps = 105/479 (21%)

Query: 665  VPVSMNPGPNMGQPQPG-----MTSNGPLP------DPSMIRGSVPNQMMPR-ITPQSGL 712
            +PVS N  P  G   P      M  +G +P       P+ +  S   Q MP  +    G 
Sbjct: 1048 LPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGS 1107

Query: 713  NQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPS 772
            N   +M   + P  P  +P  +        G+  P +  GP    PS+    LPQ Q   
Sbjct: 1108 NS-RKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPN-NMPSHV--VLPQNQLMM 1163

Query: 773  QGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSP 832
             G      PL+ + G  P           PVNS    P S G H      P       +P
Sbjct: 1164 TGPKPGPSPLSATQGATPQQP--------PVNSL---PSSHGHHFPNVAAPTQTSRPKTP 1212

Query: 833  ---SPVPSRTPTPHHTPP----------------SIGAQQPPATTIPAPVPTPPAMPPGP 873
               SP P    TP++ PP                SI    PP   I  P+P  P +  G 
Sbjct: 1213 NRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI--PLPPRPNLNRGF 1270

Query: 874  QSQALHPP---------------PRQTPTPPTTQLPQQV-----QPSLPAAPSADQPQQQ 913
              Q L+P                P    TP T +L   V     Q +  A   A     +
Sbjct: 1271 DQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSR 1330

Query: 914  PRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQV-------------SNPPSTSST 960
              S  S+  + P+P          T  SQ   ++   V             +NPP   S 
Sbjct: 1331 RSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSF 1390

Query: 961  EVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK 1020
              N+  +  +  +  V     +  D  E  +  P+D       DC+   +  E+ + ELK
Sbjct: 1391 P-NNSGLNPQNSTVSVAAVGGVVEDNKESLNV-PQD------SDCQNSQSRKEQVNIELK 1442

Query: 1021 TEIKEE------EDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESL 1073
                +E      EDQ       S P       K+   EE +  + P +    R+ P SL
Sbjct: 1443 AVPAQEVKMVVPEDQSKKDGQPSDP------NKLPSVEENKNLVSPAM----REAPTSL 1491



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 56/234 (23%), Positives = 83/234 (35%), Gaps = 42/234 (17%)

Query: 1848 PSPTPATP-TTPTGQQPTTPQTPQPTSQPQ-------PTPPNSMPPY-LPRTQAAGPVSQ 1898
            PS  PA P TT +G  P +     P   PQ       P PPN++     P  Q   P+  
Sbjct: 1675 PSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVL 1734

Query: 1899 GKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMP- 1957
               A  V  P+PP T+ P +P  PP        +Q+  E     A  Q+     Q+ +P 
Sbjct: 1735 SSRATPVQLPSPPCTSSPVVPSHPP--------VQQVKELNPDEASPQVNTSADQNTLPS 1786

Query: 1958 --PMTPMAPMGMNPPPMTRGPSGHLEPGMGP------------------TGMQQQPPWSQ 1997
                T ++P+  N P  +      +    G                   TG  ++     
Sbjct: 1787 SQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQY 1846

Query: 1998 GGLPQPQQLQSGMPRPAMMSVAQHGQPLN----MAPQPGLGQVGISPLKPGTVS 2047
            G   + +        P +M   Q    L+      P P L ++  SP+ PGT S
Sbjct: 1847 GADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTAS 1900



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 69/288 (23%), Positives = 96/288 (33%), Gaps = 74/288 (25%)

Query: 2114 QPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHN 2173
            Q   M G  G  ++  M+   PM +G     +    P   + PP G +S        N  
Sbjct: 145  QDVRMNGPMGAGNSVRMEAGFPMASGP--GIIRMNNPATVMIPPGGNVSSSMMAPGPNPE 202

Query: 2174 TMPSQFRDILRRQQM------MQQQQQQGAGPGIGPGMANHNQFQ------QPQGVGYPP 2221
              P   R   +   M      +  QQQ      + P    H+  Q      Q     +P 
Sbjct: 203  LQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPP---HHPMQPVSVNRQMNPANFPQ 259

Query: 2222 QQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQ 2281
             QQQ+ Q   QQ QQ                     Q  QQ+  QQQ+    Q  P  PQ
Sbjct: 260  LQQQQQQQQQQQQQQ---------------------QQQQQQQQQQQL----QARP--PQ 292

Query: 2282 QHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVS 2341
            QH             QQ P  +  Q  +P  VP P   +Q     PS  +QP P+   + 
Sbjct: 293  QHQ------------QQQPQGIRPQFTAPTQVPVPPGWNQ----LPSGALQPPPAQGSLG 336

Query: 2342 PQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGAS 2389
              T++              QG   +P    M  QL + P +A +   S
Sbjct: 337  TMTAN--------------QGWKKAPLPGPMQQQLQARPSLATVQTPS 370



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 151/697 (21%), Positives = 232/697 (33%), Gaps = 131/697 (18%)

Query: 427  QPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQV 486
            Q ++TG   G   PS L   Q + P    V+ + PSS    +  +  P Q ++  T  + 
Sbjct: 1160 QLMMTGPKPG---PSPLSATQGATPQQPPVNSL-PSSHGHHFPNVAAPTQTSRPKTPNRA 1215

Query: 487  QAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSE 546
              +    Q P   P    P S +S SP  +N  +    P  ++  +         P  + 
Sbjct: 1216 SPRPYYPQTPNNRPPSTEP-SEISLSPERLNASIAGLFPPQINIPL--------PPRPNL 1266

Query: 547  NASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLV---HKLVQAIFPTPDPAALKDR 603
            N      G  PT     T     Q   ++T +  N      HKL        D   +   
Sbjct: 1267 NRGFDQQGLNPT-----TLKAIGQAPSNLTMNPSNFATPQTHKL--------DSVVVNSG 1313

Query: 604  RMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQN---MLPN 660
            +  N  A  R         +N+R        +      ++  +  +  L  Q    +L N
Sbjct: 1314 KQSNSGATKRA------SPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQN 1367

Query: 661  AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDP-------SMIRGSVPNQMMPRITPQSGLN 713
                  V ++P P    P PG   N    +P       + + G V +       PQ    
Sbjct: 1368 VELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDC 1427

Query: 714  QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ 773
            Q  Q    Q  I  +  P        AQ   +  P     +  QPS+  + LP  +   +
Sbjct: 1428 QNSQSRKEQVNIELKAVP--------AQEVKMVVPEDQSKKDGQPSDPNK-LPSVE---E 1475

Query: 774  GMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQ--------- 824
              N+    ++P+  +AP S +Q+  +S   N  I PPG     +  P +           
Sbjct: 1476 NKNL----VSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVI 1531

Query: 825  PALHQNSPSPVPSRT-PTPHHTPPSIGAQQPPATTIPAPV--PTPPAM--PPGPQSQALH 879
            P L   S S  PS +   PH          P  + + + V    PP M  P    S +  
Sbjct: 1532 PTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTP 1591

Query: 880  PPPRQ-----TPTPPTTQ------LPQQVQPSLPA----------------APSADQPQQ 912
             PP Q     T  P TT       LP  +Q +L +                  SA Q   
Sbjct: 1592 LPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNA 1651

Query: 913  QPR------------------SQQSTAASVP-TPTAPLLPPQPAT--PLSQPAVSIEGQV 951
            +P+                  SQ ST  + P T  + L+PP  A   PL  P        
Sbjct: 1652 RPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSA 1711

Query: 952  SNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTE 1011
              PP+  S+   +  I   +P         +++  P P  + P   S   V+  K     
Sbjct: 1712 PVPPNALSSS-PAPNIQTGRPLVLSSRATPVQLPSP-PCTSSPVVPSHPPVQQVK--ELN 1767

Query: 1012 TEERSTELKTEIKEEEDQPSTSATQSSP----APGQS 1044
             +E S ++ T   +     S S T  SP    +PG S
Sbjct: 1768 PDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 76/319 (23%), Positives = 109/319 (34%), Gaps = 53/319 (16%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQ----AAGPVSQG--KA 1901
            P P    P     QQ   P   QP SQ Q      M   L   Q       PVSQ     
Sbjct: 998  PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP 1057

Query: 1902 AGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQI----FQRPIQHQMP 1957
             G + P +     Q     P   +++    +  + + QR    V        R + +Q  
Sbjct: 1058 RGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQES 1117

Query: 1958 PMTP-MAPMG-MNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSG-MPRPA 2014
            P  P  +P+  M   P   G      PG GP  M      S   LPQ Q + +G  P P+
Sbjct: 1118 PQNPSSSPLAEMASLPEASGSEAPSVPG-GPNNMP-----SHVVLPQNQLMMTGPKPGPS 1171

Query: 2015 MMSVAQHGQPLNMAPQPGLGQVGIS----------------PLKPGTVSQQALQNLLRTL 2058
             +S  Q   P     QP +  +  S                P  P   S +         
Sbjct: 1172 PLSATQGATP----QQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNN 1227

Query: 2059 RSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQG--QPGLQPP 2116
            R PS+   +      +  +P+ L A I   A  +      P+P +P + +G  Q GL P 
Sbjct: 1228 RPPSTEPSE------ISLSPERLNASI---AGLFPPQINIPLPPRPNLNRGFDQQGLNPT 1278

Query: 2117 TMPGQQGVHSNPAMQNMNP 2135
            T+   + +   P+   MNP
Sbjct: 1279 TL---KAIGQAPSNLTMNP 1294



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 21/149 (14%)

Query: 866  PPAMPPGP--QSQALHPPPRQTPTPPTTQLPQQVQ-PSLPAAPSADQPQQQPR------- 915
            P  +P  P   +  L PP      P    +PQ ++  S P  P+A      P        
Sbjct: 1675 PSTIPAAPLTTNSGLMPPSVAVVGP--LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL 1732

Query: 916  --SQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP- 972
              S ++T   +P+P     P  P+ P  Q    +       P  +S +VN+ A     P 
Sbjct: 1733 VLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELN------PDEASPQVNTSADQNTLPS 1786

Query: 973  SQEVKMEAKMEVDQPEPADTQPEDISESK 1001
            SQ   M + +  + P  +  +   +S SK
Sbjct: 1787 SQSTTMVSPLLTNSPGSSGNRRSPVSSSK 1815


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 161/638 (25%), Positives = 230/638 (36%), Gaps = 80/638 (12%)

Query: 1808 NIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQ 1867
            N +Q+ +QQQ Q + Q + +L    +   R       Q LP      P  P G Q    +
Sbjct: 3597 NKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLR 3656

Query: 1868 -TPQPTSQP-QPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAA 1925
             TP   + P QP  P        + Q       G  AG      P   A   L       
Sbjct: 3657 LTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLL 3716

Query: 1926 VEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMG 1985
             E  +Q+Q     Q++M   Q  Q+  Q Q      +  + +      +GP       +G
Sbjct: 3717 QERQLQLQ-----QQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ-QGPGVQTNQALG 3770

Query: 1986 PTGMQQQPPWSQGGL------PQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGIS 2039
            P      PP S  GL      PQP Q   GM  PA ++V Q   P  + PQ    QV ++
Sbjct: 3771 PKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMT 3830

Query: 2040 P---LKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSN 2096
                L    ++QQ    +   L +     QQQQ     H     +A     + +  ++S 
Sbjct: 3831 QSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQ-----HQQQGSMAGLSHLQQSLMSHSG 3885

Query: 2097 PQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQP 2156
               +  QP M   Q   Q   +  QQ +      Q     Q  +Q+  L QQQ QQQLQ 
Sbjct: 3886 QPKLSAQP-MGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ--LQQQQLQQQQQQQQLQQ 3942

Query: 2157 PMGG-MSPQAQQMNMNHNTMPSQFRDILRRQQM-------------MQQQQQQGAGPGIG 2202
                 +  Q QQ+         QF+   ++QQM              QQQQQ   GPG+ 
Sbjct: 3943 QQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMP 4002

Query: 2203 PGMANHNQFQQPQGVGYPPQQQQRMQHHMQ-----------QMQQGNMGQIGQLPQALGA 2251
                 H  F  P  +G       + Q+ +               QG    IG  P+++  
Sbjct: 4003 AKPLQH--FSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMAT 4060

Query: 2252 EAGA---SLQAYQQRLLQQQMGSPVQPNPMSPQQHM-LPNQAQSP----HLQGQ----QI 2299
            E G    SL    Q LL Q    P QP+ +  Q  + LP Q Q      H  G     Q+
Sbjct: 4061 EPGEVKPSLSGDSQLLLVQPQPQP-QPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119

Query: 2300 PNSLSNQVRSPQPV---PSPRPQSQPPHSS-----PSPRMQPQPSPHHVSPQTSSPHPGL 2351
             +  S++  S   +   PS     QP   +     P   M  +P  ++  PQ   P P L
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVL 4179

Query: 2352 VAAQANPMEQGHFASPDQNSMLSQ----LASNPGMANL 2385
             + Q  P   G    P    + +Q    LA NP + +L
Sbjct: 4180 QSGQGLP---GVGIMPTVGQLRAQLQGVLAKNPQLRHL 4214



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 98/395 (24%), Positives = 141/395 (35%), Gaps = 62/395 (15%)

Query: 724  PIVPRQTPPLQHHGQLAQPGAL-----NPPMGYGPRMQQPSNQG--------------QF 764
            P+  R +PP        +P AL       P G      QP   G              Q 
Sbjct: 367  PVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426

Query: 765  LPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSS--SSCPVNSPIMPPGSQGSHIHCPQL 822
             PQ + P        +PL P   ++P+S     S  S  P  S + PP  +      P  
Sbjct: 427  EPQLEAPLN----EEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE-----LPAS 477

Query: 823  PQP-ALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIP-APVPTPPAMPPGPQSQA-LH 879
            P P ALH + P      +P P  +P S   +  P + +  +P+  P   PP P  +  L 
Sbjct: 478  PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS 537

Query: 880  PPPRQTP-TPPTTQLPQQVQPS-LPAAPSADQPQQQPRSQQSTAASVP--TPTAP----- 930
            PPP  +P +PP  + P    P  LP +P  +  +  P  ++S  +  P  +P +P     
Sbjct: 538  PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEAS 597

Query: 931  -LLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEP 989
             L PP   +PLS P    E  +S PP  S      +      P +E  M    EV +  P
Sbjct: 598  RLFPPFEESPLSPPPE--ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 990  ADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIF 1049
                             +         + L    +E    P   A++ SP P  S     
Sbjct: 656  LPV--------------VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS-- 699

Query: 1050 KPEELRQALMPTLEALYRQDPESLPFRQ-PVDPQL 1083
             P E   A  P  ++L     E  P    P +PQL
Sbjct: 700  PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 156/667 (23%), Positives = 229/667 (34%), Gaps = 100/667 (14%)

Query: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG--------- 1860
            K+  ++QQL  +LQ AQ  +++          G  Q +  P   +  +  G         
Sbjct: 3258 KELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGL 3317

Query: 1861 ---QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPP 1917
               +QP  PQ   PT  P       + P +      G +  G+  GQ     P Q++QP 
Sbjct: 3318 AGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQ-AGLVPQQSSQPV 3376

Query: 1918 LPGPPPAAV--EMAMQIQRAAETQRQMAH-----VQIFQRPIQHQMPPMTPMAPMGMN-- 1968
            L   P   +   M M+ Q+ A  Q+Q+A+       + +   +  + P+     + +   
Sbjct: 3377 LSQKPMGTMPPSMCMKPQQLA-MQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGI 3435

Query: 1969 PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGG----LPQPQQLQSGMPRPAMMSVAQHGQP 2024
               M +G  G + PGM    +        GG    L       SG  R A       G P
Sbjct: 3436 KKVMAQGSIG-VAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSA-------GDP 3487

Query: 2025 LNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF 2084
                P P     G+         ++ L +  + L+     L++Q  + +   + + L A 
Sbjct: 3488 SQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQ--IGVHRKSRKALCA- 3544

Query: 2085 IKQRAAKYANSNPQPIPGQP----GMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGV 2140
             KQR AK A         +        Q +   Q   +  QQ  H+N   +  N  Q   
Sbjct: 3545 -KQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQ 3603

Query: 2141 QRAGLPQQQ------------------------PQQQLQPPMGGMSPQAQQMNMNHNTM- 2175
            Q+    QQQ                        P   LQPP G    QA  + +    M 
Sbjct: 3604 QQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMA 3663

Query: 2176 -PSQFRDILRRQQMMQQQQQQ---GAGPGIGP--GMANHNQFQQPQGVGYPPQQQQRMQH 2229
             P Q         + QQQQQQ   GAG   GP  G    N   +  G      Q++++Q 
Sbjct: 3664 LPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQL 3723

Query: 2230 HMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQA 2289
              Q+MQ     Q  Q  Q         +   Q    QQQ G  VQ            NQA
Sbjct: 3724 QQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQ----QQQQGPGVQ-----------TNQA 3768

Query: 2290 QSPHLQGQQIPNS---LSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSS 2346
              P  QG   P+S   L  Q  SPQP   P+    P   +    +  Q  P  + PQ   
Sbjct: 3769 LGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVA----VLQQQHPGALGPQ--G 3822

Query: 2347 PHPGLVAAQANPMEQGHFASPDQNSMLSQL--ASNPGMANLHGASATDLGLSTDNSDLNS 2404
            PH  ++  Q+  +     A   Q  M  +L  A        H    +  GLS     L S
Sbjct: 3823 PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMS 3882

Query: 2405 NLSQSTL 2411
            +  Q  L
Sbjct: 3883 HSGQPKL 3889



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 159/617 (25%), Positives = 215/617 (34%), Gaps = 109/617 (17%)

Query: 1807 LNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPT-PATPTTPTGQQPTT 1865
            + + QKL+QQQ Q   QQ Q L  ++A  Q+     QQQG    T  A    P G  P +
Sbjct: 3728 MQLAQKLQQQQQQQ--QQQQHLLGQVAIQQQ-----QQQGPGVQTNQALGPKPQGLMPPS 3780

Query: 1866 PQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQ----TAQPPLPGP 1921
                    Q  P PP      L   Q A  V Q +  G + P  P +    T    L  P
Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVA--VLQQQHPGALGPQGPHRQVLMTQSRVLSSP 3838

Query: 1922 PPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLE 1981
              A     +   R    Q+Q    Q  Q+     +  +          P ++  P G L+
Sbjct: 3839 QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQ 3898

Query: 1982 PGMGPTGMQQQPPWSQGGLPQPQQLQSGMP-RPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040
                   +QQQ    Q    Q QQLQ     +   +   Q  Q L    Q  L Q     
Sbjct: 3899 QLQQQQQLQQQQQLQQ---QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQL 3955

Query: 2041 LKPGTVSQQALQ-----------NLLRTLRSPSSPLQQQQVLS-------ILH------A 2076
             +     QQ  Q           N  RTL SP    QQQ  L        + H       
Sbjct: 3956 QQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015

Query: 2077 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQP---GLQPPTMPGQQGVHSNPAMQNM 2133
             P LL    +Q     A S+ +   G P   QG P   G  P +M  + G         +
Sbjct: 4016 GPTLLLTGKEQNTVDPAVSS-EATEG-PSTHQGGPLAIGTTPESMATEPG--------EV 4065

Query: 2134 NPMQAGVQRAGLPQQQPQQ-----QLQPPMGGMSPQAQQMNMNH---------------- 2172
             P  +G  +  L Q QPQ      QLQPP+     Q QQ+++ H                
Sbjct: 4066 KPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSS 4125

Query: 2173 --NTMP---------------SQFRDILRRQQ-MMQQQQQQGAGPGIGPGMANHNQFQQP 2214
              +++P               S  +++L  QQ M+++  Q   GP            Q  
Sbjct: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185

Query: 2215 QGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA-YQQRLLQQQMG--- 2270
             GVG  P   Q     ++   QG + +  QL + L  +    LQA   QR LQQ      
Sbjct: 4186 PGVGIMPTVGQ-----LRAQLQGVLAKNPQL-RHLSPQQQQQLQALLMQRQLQQSQAVRQ 4239

Query: 2271 SPVQPNP---MSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSP 2327
            +P    P    SP Q +L  Q Q     G Q    L      P+P   PR  + P   S 
Sbjct: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ-TGPLQELGAGPRPQGPPRLPAPPGALST 4298

Query: 2328 SPRMQP-QPSPHHVSPQ 2343
             P + P  P+P   SPQ
Sbjct: 4299 GPVLGPVHPTPPPSSPQ 4315



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 73/321 (22%), Positives = 120/321 (37%), Gaps = 43/321 (13%)

Query: 669 MNPGPNMGQ--PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ--SGLNQFGQMSMAQPP 724
           M+P P + +  P P ++   P P+ S +  S P +  P   P   S L+   + S   PP
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPL--SPPPEESPTSPPPEASRLSPPPEDSPTSPP 701

Query: 725 IVPRQTPPLQHHGQLAQPGALNP--PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPL 782
                  P      ++ P   +P  P+   P++   S      P+ + P          L
Sbjct: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761

Query: 783 APSSGQAPVSQAQMSSSSCPV-NSPIMPPGSQGSHIH--------CPQLPQPAL------ 827
           +P + +  +S        C V   P + P ++G H+          PQ  +P L      
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821

Query: 828 ----------HQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQA 877
                     H +  S  P  +P P  +  S   ++PP +  P   P  P   P P+   
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881

Query: 878 LHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA 937
           L PPP +    P    P   +P  P  P +  P++ P S     +  P+ +  L+PP P 
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEP--PLSPLPEELPLS----PSGEPSLSPQLMPPDPL 935

Query: 938 TPLSQPAVSIEGQVSNPPSTS 958
            P   P ++     + PP+ S
Sbjct: 936 PPPLSPIIT----AAAPPALS 952



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 138/582 (23%), Positives = 214/582 (36%), Gaps = 121/582 (20%)

Query: 1807 LNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTP 1866
            L  +Q+L+QQQLQ + QQ Q+ +++   +Q+     QQQ               QQ    
Sbjct: 3920 LQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ---------------QQQQQQ 3964

Query: 1867 QTPQPTSQPQPTPPNSMPPYL-PRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAA 1925
            Q  Q   Q Q    N     L P+ Q    V+ G          P   A+P      P A
Sbjct: 3965 QFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG----------PGMPAKPLQHFSSPGA 4014

Query: 1926 VEMAMQIQ-RAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGM 1984
            +   + +  +   T       +  + P  HQ  P+     +G  P  M   P G ++P +
Sbjct: 4015 LGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLA----IGTTPESMATEP-GEVKPSL 4069

Query: 1985 -GPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKP 2043
             G + +    P  Q   PQP  LQ    +P +    Q  Q +++    G G  G    + 
Sbjct: 4070 SGDSQLLLVQPQPQ---PQPSSLQL---QPPLRLPGQQQQQVSLLHTAGGGSHG----QL 4119

Query: 2044 GTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQ 2103
            G+ S     ++   L  PS  L  Q       +  Q L    +    +   +N  P P +
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQP-----GSMTQNLLGPQQPMLERPMQNNTGPQPPK 4174

Query: 2104 PGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSP 2163
            PG          P +   QG+     M  +  ++A +Q  G+  + PQ      +  +SP
Sbjct: 4175 PG----------PVLQSGQGLPGVGIMPTVGQLRAQLQ--GVLAKNPQ------LRHLSP 4216

Query: 2164 QAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQ-----QPQGVG 2218
            Q QQ          Q + +L ++Q+ Q Q  +   P   PG    +  Q     QPQ  G
Sbjct: 4217 QQQQ----------QLQALLMQRQLQQSQAVRQTPPYQEPG-TQTSPLQGLLGCQPQLGG 4265

Query: 2219 YPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPN-- 2276
            +P  Q          +Q+   G   Q P  L A  GA        L    +  PV P   
Sbjct: 4266 FPGPQ-------TGPLQELGAGPRPQGPPRLPAPPGA--------LSTGPVLGPVHPTPP 4310

Query: 2277 PMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVP-SPRPQSQPPHSSPSPRMQPQP 2335
            P SPQ+   P+Q  SP  Q       L  + + P   P +P+PQ         P ++P P
Sbjct: 4311 PSSPQEPKRPSQLPSPSSQ-------LPTEAQLPPTHPGTPKPQ--------GPTLEPPP 4355

Query: 2336 SPHHVSPQTSSPHPGLVAAQANPMEQ----GHFASPDQNSML 2373
                VSP  +     L +    P +          P+Q+S++
Sbjct: 4356 G--RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 233/1098 (21%), Positives = 376/1098 (34%), Gaps = 169/1098 (15%)

Query: 17   KLSSPALSASASDGTD-FGSLFDLEHDLP--DELINSTELGLTNGGDINQLQTSLGMVQD 73
            +L+   L    + G D  G+L +LE + P  D+L+N  E  L    D  +L T  G  +D
Sbjct: 3008 ELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTD-PELDT--GDKKD 3064

Query: 74   AASKHKQLSELL-----RSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQ 128
              ++H +L E       R      +  G  GP +     A  S P L  +   VK P  +
Sbjct: 3065 IFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVK-PKVE 3123

Query: 129  AGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMP 188
             G           G +  P Q T  + +P  +PA   N+ +  G+ PG    G+    M 
Sbjct: 3124 EG-----------GRHPSPCQFT--IATPKVEPAPAANS-LGLGLKPGQSMMGSRDTRMG 3169

Query: 189  NQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMG-GQTGLRGPQPLKMGMM 247
                + S   G   +   +   G G   +LLT      SP  G G + L     L+ G +
Sbjct: 3170 TGPFSSS---GHTAEKASFGATG-GPPAHLLTP-----SPLSGPGGSSLLEKFELESGAL 3220

Query: 248  NNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMD-----KKAVPGGGMPNM 302
              P   G P          ASG  L     +++++ L     D     KK +      + 
Sbjct: 3221 TLP---GGP---------AASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSA 3268

Query: 303  GQQPAPQVQQPG-----LVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQ----- 352
              QPA Q QQ       L  P      S  H          QQQL L L   +       
Sbjct: 3269 QLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQP 3328

Query: 353  -RREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDC 411
                Q      Q  L     M +   HM   Q G    +    SS+ ++S          
Sbjct: 3329 LMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLS---------- 3378

Query: 412  PVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAAL 471
                          Q+P+ T  P     P  L + QQ A +    + +D  + E     +
Sbjct: 3379 --------------QKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPI 3424

Query: 472  GLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDS 531
                 V  +    +V A+      PG + Q       +S     ++GG     PS  SD 
Sbjct: 3425 AKAKMV-ALKGIKKVMAQGSIGVAPGMNRQ------QVSLLAQRLSGG-----PS--SDL 3470

Query: 532  MLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAI 591
              H A  S     + + S P   P PT AQ    G+  +  +   ++   H    L   +
Sbjct: 3471 QNHVAAGSGQERSAGDPSQPRPNP-PTFAQ----GVINEADQRQYEEWLFHTQQLLQMQL 3525

Query: 592  FPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTR 651
                +   +  +  + L A  R  +    E     AE   L+ E+  KIQK+L++ R+ +
Sbjct: 3526 KVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQ 3585

Query: 652  LQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMP------- 704
             +  N++                  Q    + +  P   P ++   +P Q++P       
Sbjct: 3586 KEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLT-KLPGQLLPGHGLQPP 3644

Query: 705  -----------RITPQSGLNQFGQMSMAQPPIVPRQTPPLQHH---GQLAQPGALNPPMG 750
                       R+TP  G+   GQ           Q    QH    G LA P     P  
Sbjct: 3645 QGPPGGQAGGLRLTP-GGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703

Query: 751  YGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSS---------GQAPVSQAQMSSSSC 801
               R   P ++     Q Q   Q M +                  GQ  + Q Q      
Sbjct: 3704 LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGV 3763

Query: 802  PVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA 861
              N   + P  QG       L  P+ HQ     V   +P P   P  +     PA     
Sbjct: 3764 QTNQ-ALGPKPQG-------LMPPSSHQG--LLVQQLSPQPPQGPQGM---LGPAQVAVL 3810

Query: 862  PVPTPPAM-PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSL--PAAPSADQPQQQPRSQQ 918
                P A+ P GP  Q L    R   +P   QL QQ Q  +      +  Q QQQ   QQ
Sbjct: 3811 QQQHPGALGPQGPHRQVLMTQSRVLSSP---QLAQQGQGLMGHRLVTAQQQQQQQQHQQQ 3867

Query: 919  STAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKM 978
             + A +      L+     +   QP +S +   S        ++  Q   ++Q  Q+++ 
Sbjct: 3868 GSMAGLSHLQQSLM-----SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQ 3922

Query: 979  EAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQP-----STS 1033
            + +++  Q +    Q + + + + +  + +  + +++  + + + ++++ Q      + S
Sbjct: 3923 QQQLQQQQLQ-QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981

Query: 1034 ATQSSPAPGQSKKKIFKP 1051
             T  SP   Q ++    P
Sbjct: 3982 RTLLSPQQQQQQQVALGP 3999



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 112/528 (21%), Positives = 188/528 (35%), Gaps = 68/528 (12%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPT-PPNSMPPYLPRTQAAGPVSQGKAAGQVT 1906
            P    A P    G Q   PQ   P ++  P  PP    P  P  + + P S    A +++
Sbjct: 411  PLQCEAKPLGKAGVQ-LEPQLEAPLNEEMPLLPPPEESPLSPPPEES-PTSPPPEASRLS 468

Query: 1907 PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMG 1966
            PP P +    PLP         A+ + R  E        +  + P+    P  +P +P+ 
Sbjct: 469  PP-PEELPASPLPE--------ALHLSRPLEESPLSPPPE--ESPLSPP-PESSPFSPLE 516

Query: 1967 MNP--PPMTRGPSGHLEPGMGPT--GMQQQPPWSQGGL-PQPQQLQSGMPRPAM-MSVAQ 2020
             +P  PP    PS  LE  + P        PP+ +  L P P++L +  P  A  +S   
Sbjct: 517  ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576

Query: 2021 HGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSP---SSPLQQQQVLSILHAN 2077
               P++  P+        SP+ P   + +       +  SP    SPL      S L   
Sbjct: 577  EESPMSPPPEE-------SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629

Query: 2078 PQLLAAFIKQRAA------KYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQ 2131
            P+          +      + +  +P P+  +   P  +  L PP  P +      P   
Sbjct: 630  PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP--PEESPTSPPPEAS 687

Query: 2132 NMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQ 2191
             ++P       +  P+  P           SP  +   M+     S    +    Q+  +
Sbjct: 688  RLSPPPEDSPTSPPPEDSPA----------SPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737

Query: 2192 QQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGA 2251
             +    GP + P     +   +P+     PQ ++   H   Q ++  +  + + P     
Sbjct: 738  SE----GPHLSPRPEEPHLSPRPEEPHLSPQAEE--PHLSPQPEEPCLCAVPEEPHLSPQ 791

Query: 2252 EAGASLQAYQQRL-----LQQQMGSPVQPNP-MSPQ---QHMLPNQAQSPHLQGQQIPNS 2302
              G  L    + L      ++   SPV   P +SPQ    H+ P Q++ P L  +   + 
Sbjct: 792  AEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP-QSEEPCLSPRPEESH 850

Query: 2303 LSNQVRSPQPVPSPRPQSQPPHSSPSPR---MQPQPSPHHVSPQTSSP 2347
            LS ++  P   P P    + P   P+P    + P P    +SP    P
Sbjct: 851  LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP 898



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 107/503 (21%), Positives = 168/503 (33%), Gaps = 73/503 (14%)

Query: 1906 TPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQM-----AHVQI---FQRPIQHQMP 1957
            TP   P        G P      +MQ +     Q +      A VQ+    + P+  +MP
Sbjct: 380  TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439

Query: 1958 PMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMP-RPAMM 2016
             + P     ++PPP     S   E           PP      P P+ L    P   + +
Sbjct: 440  LLPPPEESPLSPPPEESPTSPPPE-----ASRLSPPPEELPASPLPEALHLSRPLEESPL 494

Query: 2017 SVAQHGQPLNMAPQPG-LGQVGISPLKPGTVSQQALQNLLRTLRSP---SSPLQQQQVLS 2072
            S      PL+  P+      +  SPL P   S  +    L T  SP   +SPL      S
Sbjct: 495  SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS--PALETPLSPPPEASPLSPPFEES 552

Query: 2073 ILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQN 2132
             L   P+ L       A++ +       P     P   P  + P  P  +     P  + 
Sbjct: 553  PLSPPPEELPTSPPPEASRLS-------PPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605

Query: 2133 MNPMQAGVQRAGLPQQQPQQQLQPPM--GGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQ 2190
             +P+    + + L       +L PP     MSP  ++  M+     S+   +    ++  
Sbjct: 606  -SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664

Query: 2191 QQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALG 2250
              ++    P               +    PP +  R+    +             P +  
Sbjct: 665  PPEESPLSP------------PPEESPTSPPPEASRLSPPPEDS-----------PTSPP 701

Query: 2251 AEAGASLQAYQQRLLQQQMG-SPVQPNPMSPQ-------QHMLPNQAQSPHLQGQQIPNS 2302
             E   +    +  L+   +  SP+ P P  PQ        H+ P + + PHL  +     
Sbjct: 702  PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP-RPEEPHLSPRPEEPH 760

Query: 2303 LSNQVRSPQPVPSPRPQS-----QPPHSSPS---PRMQPQPSPHHVSPQTSSPHPGLVAA 2354
            LS Q   P   P P         + PH SP    P + PQP   H+SPQT  PH   V  
Sbjct: 761  LSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPE 820

Query: 2355 Q---ANPMEQGHFASPDQNSMLS 2374
            +   +   E+ H +   +   LS
Sbjct: 821  EPCLSPQPEESHLSPQSEEPCLS 843



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 133/585 (22%), Positives = 204/585 (34%), Gaps = 109/585 (18%)

Query: 1846 GLPSPTP---ATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM----PPYLPRTQAAGPVSQ 1898
            GL   TP     P TP   Q   PQ+P    +PQ  PP       PP  P     G  + 
Sbjct: 2318 GLELKTPDVFKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376

Query: 1899 GKAAGQVTP---PTPPQT--AQPP--LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951
              A   +TP   P PP++  A PP  LP  P + V  + Q Q ++++        +  RP
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP-------LTPRP 2429

Query: 1952 IQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMP 2011
            +  +    +P+ P   +P P +R PS        P       P  +   PQP ++     
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPS-------RPQSRDPFAPLHKPPRPQPPEVAFKAG 2482

Query: 2012 RPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVL 2071
              A  S+   G P  +   P         L     S Q        +RSP +        
Sbjct: 2483 SLAHTSLGAGGFPAALPAGPA------GELHAKVPSGQP----PNFVRSPGT-------- 2524

Query: 2072 SILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQG-----QPGLQPPTMPGQQGVHS 2126
                  P  +     Q   + +   P P PG P  P G      PG   PT+   Q  + 
Sbjct: 2525 GAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP-PPHGINSHFGPG---PTLGKPQSTNY 2580

Query: 2127 NPAMQNMNPMQAGV--------QRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQ 2178
              A  N +P  + +        +  GL   +P   L PP    +P      ++H    SQ
Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPP----APDGSLPYLSHGA--SQ 2634

Query: 2179 FRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP--QGVGYPPQQQQRMQHHMQQM-- 2234
               I      +++++  G G G     A     Q P   G+     ++QR +  ++++  
Sbjct: 2635 RSGI---TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLI 2691

Query: 2235 -QQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQ--PNPMSPQQHMLPNQAQS 2291
             QQ     + Q  +   A AGA             +G P      P SP    L ++ Q+
Sbjct: 2692 RQQIQRNTLRQEKETAAAAAGA-------------VGPPGSWGAEPSSPAFEQL-SRGQT 2737

Query: 2292 PHLQGQQ-------IPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQT 2344
            P    Q         P+ LS  +  P   PS    S+PP  +    M           Q 
Sbjct: 2738 PFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQA 2797

Query: 2345 ---SSPHPGLVAAQAN-----PMEQGHFASPDQNSMLSQLASNPG 2381
                +P+PG +  Q         +Q   A+  + +M ++  S PG
Sbjct: 2798 FYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 116/543 (21%), Positives = 189/543 (34%), Gaps = 72/543 (13%)

Query: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP----PYLPRTQAAGPVSQGKAAGQ 1904
            SP   +P +P  + P +P    P S P    P S P    P  P  +   P S    A +
Sbjct: 513  SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL-PTSPPPEASR 571

Query: 1905 VTPP------TPPQTAQPPLPGPPPAAVEMAMQIQRA------AETQRQMAHVQIFQRPI 1952
            ++PP      +PP    P    PPP A  +    + +       E+            P 
Sbjct: 572  LSPPPEESPMSPPPEESP--MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629

Query: 1953 QHQMPPMTPMAPMGMNPPPMTRGPS-----GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQ 2007
                P   P     M+PPP     S       L P    + +   P  S    P      
Sbjct: 630  PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689

Query: 2008 SGMPRPAMMSVAQHGQPLNMAPQPGLGQVGI--SPLKPGTVSQQALQNLLRTLRSPSSPL 2065
            S  P  +  S      P +  P+  L  + +  SPL P     Q      R+     SP 
Sbjct: 690  SPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP---RSEGPHLSPR 746

Query: 2066 QQQQVLSILHANPQLLAAFIKQRAAKYANSNPQP-IPGQPGMPQGQPGLQPPTMPGQQGV 2124
             ++  LS     P L         A+  + +PQP  P    +P+     +P   P  +G 
Sbjct: 747  PEEPHLSPRPEEPHL------SPQAEEPHLSPQPEEPCLCAVPE-----EPHLSPQAEGP 795

Query: 2125 HSNPAMQ--NMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDI 2182
            H +P  +  +++P       + +P ++P    QP    +SPQ+++  ++     S     
Sbjct: 796  HLSPQPEELHLSPQTEEPHLSPVP-EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854

Query: 2183 LRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPPQQQQRMQHHMQQMQQGNMGQ 2241
            L +  +  + ++    PG         Q   P+ +  +PP  +  +   + +      G+
Sbjct: 855  LEKPPLSPRPEKPPEEPG---------QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905

Query: 2242 --IGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQI 2299
              +  LP+ L           +  L  Q M     P P+SP        A SP L   + 
Sbjct: 906  PPLSPLPEELPLSPSG-----EPSLSPQLMPPDPLPPPLSPIITAAAPPALSP-LGELEY 959

Query: 2300 PNSLSNQVRSPQPVPSP---RPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQA 2356
            P           P+ +P    P S PP ++ +    P+P P  + P    P PG     A
Sbjct: 960  PFGAKGDSDPESPLAAPILETPISPPPEANCT---DPEPVPPMILP----PSPGSPVGPA 1012

Query: 2357 NPM 2359
            +P+
Sbjct: 1013 SPI 1015



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 120/558 (21%), Positives = 198/558 (35%), Gaps = 95/558 (17%)

Query: 1847 LPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPP-------YLPRTQAAGPVSQG 1899
            LP P  +  + P  + PT+P  P   S+  P PP  +P        +L R     P+S  
Sbjct: 441  LPPPEESPLSPPPEESPTSP--PPEASRLSP-PPEELPASPLPEALHLSRPLEESPLSPP 497

Query: 1900 KAAGQVTPPTPPQTA----------QPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQ 1949
                 ++P  PP+++           PP   PP  A+E  +     A             
Sbjct: 498  PEESPLSP--PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555

Query: 1950 RPIQHQMPPMTPMAPMGMNPPP--MTRGPSGHLEP-GMGPTGMQQQPPWSQGGLPQPQQL 2006
             P   ++P   P     ++PPP      P     P    P   +  PP+ +  L  P + 
Sbjct: 556  PP-PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614

Query: 2007 QSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSP--SSP 2064
                P P    ++   +   M+P P   +  +SP  P  VS+ +   ++  L  P   SP
Sbjct: 615  SPLSPPPEASRLSPPPEDSPMSPPP--EESPMSP--PPEVSRLSPLPVVSRLSPPPEESP 670

Query: 2065 LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP-----TMP 2119
            L      S     P+          A   +  P+  P  P  P+  P   PP     ++P
Sbjct: 671  LSPPPEESPTSPPPE----------ASRLSPPPEDSPTSP-PPEDSPASPPPEDSLMSLP 719

Query: 2120 GQQG-VHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQ 2178
             ++  +   P    + P   G   +  P ++P    +P    +SPQA++ +++    P  
Sbjct: 720  LEESPLLPLPEEPQLCPRSEGPHLSPRP-EEPHLSPRPEEPHLSPQAEEPHLS----PQP 774

Query: 2179 FRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQ-- 2236
                L           Q  GP + P         QP+ +   PQ +   + H+  + +  
Sbjct: 775  EEPCLCAVPEEPHLSPQAEGPHLSP---------QPEELHLSPQTE---EPHLSPVPEEP 822

Query: 2237 ---GNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPH 2293
                   +    PQ+   E   S +  +  L  +    P+ P P  P +   P Q  +P 
Sbjct: 823  CLSPQPEESHLSPQS--EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE--PGQCPAP- 877

Query: 2294 LQGQQIP-------NSLSNQVRSP------QPVPSPRPQSQPPHSSPSPRMQPQPSPHHV 2340
               +++P        SLS  +  P      +P  SP P+  P   S  P + PQ  P   
Sbjct: 878  ---EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934

Query: 2341 SPQTSSPHPGLVAAQANP 2358
             P   SP   ++ A A P
Sbjct: 935  LPPPLSP---IITAAAPP 949



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 109/497 (21%), Positives = 160/497 (32%), Gaps = 106/497 (21%)

Query: 658  LPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQ 717
            LP    + P S   GP++  P+P      P P+   +    P    P ++PQ       +
Sbjct: 728  LPEEPQLCPRS--EGPHLS-PRPEEPHLSPRPEEPHLS---PQAEEPHLSPQPE-----E 776

Query: 718  MSMAQPPIVPRQTPPLQHHGQLAQPGALN----------PPMGYGPRMQQPSNQGQFLPQ 767
              +   P  P  +P  +      QP  L+           P+   P +     +    PQ
Sbjct: 777  PCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836

Query: 768  TQFPSQGMNVTNIPLAPSSGQAPVSQA------QMSSSSCPVNSPIMPPGSQGSHIHCPQ 821
            ++ P          L+P   + P+S        +      P   P+ PP  + S    P 
Sbjct: 837  SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL--SPL 894

Query: 822  LPQPALHQNSP---SPVPSRTPTPHHTPPSIGAQQPPATTIPAPVP------TPPAMPP- 871
            L +PAL +      SP+P   P      PS+  Q  P   +P P+        PPA+ P 
Sbjct: 895  LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954

Query: 872  -------------GPQSQA--------LHPPPRQT-----PTPPTTQLPQQVQPSLPAAP 905
                          P+S          + PPP        P PP    P    P  PA+P
Sbjct: 955  GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014

Query: 906  SADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPA----------VSIEGQVSNPP 955
               +P     S     + VP  + P     PA PLS P+          VS E ++    
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074

Query: 956  STSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQP------EDISESKVEDCKMES 1009
            +   +E    A+     S        +    P PA          ED +     D     
Sbjct: 1075 TEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ 1134

Query: 1010 TETEERSTELKTEIK-------EEEDQPST----------SATQSSPAPGQSKKKIFKPE 1052
             E  +    L +E+K        EE  P T          +A Q SP   Q        E
Sbjct: 1135 PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQ--------E 1186

Query: 1053 ELRQALMPTLEALYRQD 1069
            E R  + PT   L + D
Sbjct: 1187 EPRAPVAPTPPTLIKSD 1203



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 131/559 (23%), Positives = 207/559 (37%), Gaps = 130/559 (23%)

Query: 493  NQQPGQSP--QGMRPMSNM-SASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENAS 549
            ++ P Q P  QG  P+ N+ S+SPM    G+  Q+P L  DS       S  P   ++  
Sbjct: 1917 SRTPLQRPFLQGGLPLGNLPSSSPMDSYPGL-CQSPFL--DSRERGGFFSPEPGEPDSPW 1973

Query: 550  VPSLGPMP-TAAQPSTTG----------IRKQWHEDITQDLRNHLVHKLVQAI-FPT--- 594
              S G  P T   P+T G            ++W +D      + +   L   I FP    
Sbjct: 1974 TGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQ 2033

Query: 595  --PDPAALKDRRMENLVAYARKVEGD-----MYESANNRAEYYHLLAEKIYKIQKELEEK 647
              PD ++    R + ++   RKV        + ++ +NRA      A +I K+QK+ E  
Sbjct: 2034 DYPDWSS----RCKQIMKLWRKVPAADKAPYLQKAKDNRA------AHRINKVQKQAE-- 2081

Query: 648  RRTRLQKQNMLPNAAGMVP-----VSMNPGPN-MGQPQPGMTSN---GPLPDPSMIRGSV 698
              +++ KQ  + + A         + + P P  +G P P        G    P+ +  S 
Sbjct: 2082 --SQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSA 2139

Query: 699  PNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTP-----------PLQHH----------- 736
               + P      G +  G++ +  PP VP Q P           PL+             
Sbjct: 2140 DGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPY 2199

Query: 737  -------------GQLAQPGALNPPMGY----GPRMQQPSNQGQFLPQT----------Q 769
                         G  ++PGA  P   +    G    QPS    FL             +
Sbjct: 2200 PSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPE 2259

Query: 770  FPSQGMNVTNIPLA--PSSGQA----PVSQAQMSSSSC---PVNSPIMPPGSQGSHIHCP 820
             P  G    + PL   P  G++     V + ++ +SS    P N   +   S G+H+   
Sbjct: 2260 SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGL 2319

Query: 821  QLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMP----PGPQSQ 876
            +L  P + +   +P+  R        P +G +        A  P+PP+ P    PG  + 
Sbjct: 2320 ELKTPDVFK---APLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376

Query: 877  ALHPPP---RQTPTPPTT--QLPQQVQPS-----LPAAPSADQPQQQPRSQQ--STAASV 924
                PP   R  P PP +   LP +  PS     +PA+P +    Q P + +  S  A  
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436

Query: 925  PTPTAPLLPPQPATPLSQP 943
            P+P  P    Q   P S+P
Sbjct: 2437 PSPVTPRF--QSPDPYSRP 2453



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 71/298 (23%), Positives = 94/298 (31%), Gaps = 37/298 (12%)

Query: 669  MNPGPNMGQPQ-PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVP 727
            + P  +  +PQ PG+      P P+      P        P S  + +     AQPP+ P
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY-----AQPPLTP 2385

Query: 728  RQTPPLQHHGQLAQPGAL-NPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPL---- 782
            R  PP         P +L + P    P   Q  +  Q  P T  P         P+    
Sbjct: 2386 RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQS-PLTPRPLSAEAFCPSPVTPRF 2444

Query: 783  -APSSGQAPVSQAQMSSSSCPVNSPIMPP----------------GSQGSHIHCPQLPQP 825
             +P     P S+ Q      P++ P  P                 G+ G     P  P  
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504

Query: 826  ALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT 885
             LH   PS  P        T   +G   P   T P  V  P   PP PQ     PPP   
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL--PPPHGI 2562

Query: 886  PTP----PTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939
             +     PT   PQ    ++  A     P   P    S +       +PL PP    P
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTV--ATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPP 2618



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 60/277 (21%), Positives = 94/277 (33%), Gaps = 46/277 (16%)

Query: 813  QGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPG 872
            +G H+   Q  +P   Q    P+              G Q  P   + AP+     + P 
Sbjct: 397  KGGHVTSMQPKEPGPLQCEAKPLGKA-----------GVQLEPQ--LEAPLNEEMPLLPP 443

Query: 873  PQSQALHPPPRQTPTPPTTQLPQQVQP--SLPAAPSADQPQQQPRSQQSTAASVPTPTAP 930
            P+   L PPP ++PT P  +  +   P   LPA+P  +          +   S P   +P
Sbjct: 444  PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPE----------ALHLSRPLEESP 493

Query: 931  LLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPA 990
            L PP   +PLS P          P S+  + +    ++   P +E      +E     P 
Sbjct: 494  LSPPPEESPLSPP----------PESSPFSPLEESPLS---PPEESPPSPALETPLSPPP 540

Query: 991  DTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFK 1050
            +  P             E +       EL T    E  + S    +S  +P   +  +  
Sbjct: 541  EASPLSPP--------FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592

Query: 1051 PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP 1087
            P E  +   P  E+     PE  P   P +   L  P
Sbjct: 593  PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 94/391 (24%), Positives = 142/391 (36%), Gaps = 52/391 (13%)

Query: 659  PNAAGMVPVSMNPGPNMGQPQPGMTSNG--------PLPDPSMIRGSVPNQMMPRITPQS 710
            P A G  P SM   P  G+ +P ++ +         P P PS ++   P ++  +   Q 
Sbjct: 4048 PLAIGTTPESMATEP--GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105

Query: 711  GL---------NQFGQMSMAQPPIVPRQ-TPPLQHHGQLAQPGALNPPMGYGPR--MQQP 758
             L          Q G  S ++   VP     P    G   QPG++   +  GP+  M + 
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGD--QPGSMTQNL-LGPQQPMLER 4162

Query: 759  SNQGQFLPQTQFPS----QGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQG 814
              Q    PQ   P      G  +  + + P+ GQ   +Q Q   +  P    + P   Q 
Sbjct: 4163 PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR-AQLQGVLAKNPQLRHLSPQQQQQ 4221

Query: 815  SH--IHCPQLPQP-ALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTP-PAMP 870
                +   QL Q  A+ Q  P   P    +P      +   QP     P P   P   + 
Sbjct: 4222 LQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ---GLLGCQPQLGGFPGPQTGPLQELG 4278

Query: 871  PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAP 930
             GP+ Q    PPR  P PP       V   +   P    PQ+  R  Q  + S   PT  
Sbjct: 4279 AGPRPQG---PPR-LPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334

Query: 931  LLPP-QPATPLSQ-PAVS-IEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQP 987
             LPP  P TP  Q P +    G+VS   +  +  + S+ +    P   +      E  +P
Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL-----AETQKP 4389

Query: 988  EPADTQP---EDISESKVEDCKMESTETEER 1015
            E +   P   + ++   V +    S + E R
Sbjct: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPR 4420



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 30/129 (23%)

Query: 827  LHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTP 886
            L Q SP+P P   PT H    ++         + AP P  P+ PP P    L P P   P
Sbjct: 4879 LKQESPAPEP---PTQHSYTYNVSNLD--VRQLSAPPPEEPSPPPSP----LAPSPASPP 4929

Query: 887  TPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVS 946
            T P  +LP +        P A+ P             VP+P      P+ A P  +    
Sbjct: 4930 TEPLVELPTE--------PLAEPP-------------VPSPLPLASSPESARPKPRARPP 4968

Query: 947  IEGQVSNPP 955
             EG+ S PP
Sbjct: 4969 EEGEDSRPP 4977



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 75/310 (24%), Positives = 105/310 (33%), Gaps = 53/310 (17%)

Query: 726  VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPS 785
            + R T   +     A  GA+ PP  +G     P+ +     QT F       + + L PS
Sbjct: 2695 IQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPS 2754

Query: 786  SGQAPV-------SQAQMS-------SSSCPVNSPIMPPGSQGSHIHCP-------QLPQ 824
                P+       S  ++S        SS  VNS  +  GSQ  +   P       Q  Q
Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQ 2814

Query: 825  PALHQNSPSPVPS------RTPTPHHTPPSIGAQQ--PPATTIPAPVPTPPAMPPGPQSQ 876
              L Q   +   +          P    P +G Q    P   I   +P P    PGP   
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGP 2874

Query: 877  A----LHPPPRQTPTPPTTQLPQQVQPSLPA-APSADQPQQ-QPRSQQSTAASVPTPTAP 930
            A    L    ++   P  T  P Q  P  P   P ++ P +  P   +  A S   P  P
Sbjct: 2875 AQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKP 2934

Query: 931  LLPPQPATPLS-QPAVSIEGQ--------VSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981
              PP P    S  P    +G         V+ PP  SSTE+        +P+       K
Sbjct: 2935 SAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPP--SSTELG-------RPNPLALEAGK 2985

Query: 982  MEVDQPEPAD 991
            +  + PE  D
Sbjct: 2986 LPCEDPELDD 2995



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 59/287 (20%), Positives = 91/287 (31%), Gaps = 49/287 (17%)

Query: 838  RTPTPHHTPPSIGAQQPPATTIPAPVPTP-----PAMPPG---PQSQALHPPPRQTPTPP 889
            R+    HTP       P     P   P          P G      Q   P P Q    P
Sbjct: 359  RSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP 418

Query: 890  TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEG 949
              +   Q++P L A  + + P   P  +           +PL PP   +P S P  +   
Sbjct: 419  LGKAGVQLEPQLEAPLNEEMPLLPPPEE-----------SPLSPPPEESPTSPPPEA--S 465

Query: 950  QVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMES 1009
            ++S PP         +A+   +P +E  +    E     P    PE    S +E+  +  
Sbjct: 466  RLSPPPEELPASPLPEALHLSRPLEESPLSPPPE---ESPLSPPPESSPFSPLEESPLSP 522

Query: 1010 TETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQD 1069
             E    S  L+T +      P   A+  SP                    P  E+     
Sbjct: 523  PEESPPSPALETPLS-----PPPEASPLSP--------------------PFEESPLSPP 557

Query: 1070 PESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQ 1116
            PE LP   P +   L  P     +  P + S +    +  +   P++
Sbjct: 558  PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 136/637 (21%), Positives = 201/637 (31%), Gaps = 130/637 (20%)

Query: 1807 LNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTP 1866
            +N  QK  + Q+  + +   + R+         +  Q   L SP PA   T     PTTP
Sbjct: 2073 INKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP 2132

Query: 1867 QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAV 1926
                 ++     PP    P        GP S G+   ++ P  P Q     +P   P  +
Sbjct: 2133 AGLSTSADGFLKPPAGSVP--------GPDSPGELFLKLPPQVPAQ-----VPSQDPFGL 2179

Query: 1927 EMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
              A  ++    T                  PP  P  P     P           PG G 
Sbjct: 2180 APAYPLEPRFPT-----------------APPTYPPYPSPTGAPAQPPMLGASSRPGAGQ 2222

Query: 1987 TGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLG-----QVGISPL 2041
             G     P      P   + Q   P P +         L +   PG+G     +  +SP 
Sbjct: 2223 PGEFHTTP------PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP- 2275

Query: 2042 KPGTVSQQALQNLLRTL--RSPS----------SPLQQQQVLSILHANPQLLAAFIKQRA 2089
             P   S++AL+     L   SPS          SP     +  +    P +  A +  RA
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335

Query: 2090 AKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGL---P 2146
            +       Q  P  PG+     GL+P   P  Q +  +P      P    + R G    P
Sbjct: 2336 S-------QVEPQSPGL-----GLRPQEPPPAQALAPSP------PSHPDIFRPGSYTDP 2377

Query: 2147 QQQP--QQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPG 2204
              QP    + QPP     P      +   ++PS   D   R     Q Q     P     
Sbjct: 2378 YAQPPLTPRPQPP-----PPESCCALPPRSLPS---DPFSRVPASPQSQSSSQSPLTPRP 2429

Query: 2205 MANH--------NQFQQPQGVGYPPQQQQ------------RMQHHMQQMQQGNMGQ--- 2241
            ++           +FQ P     PP + Q            R Q      + G++     
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489

Query: 2242 -IGQLPQALGA----EAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQG 2296
              G  P AL A    E  A + + Q     +  G+       SP +   P     P L  
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL-- 2547

Query: 2297 QQIPNSLSNQVRSPQPVPS-PRPQSQPPHSSPSPRM-QPQPSPHHVSPQTSSPHPGLVAA 2354
                       + P P P  P P     H  P P + +PQ + + V+     P    +  
Sbjct: 2548 -----------KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596

Query: 2355 QANPMEQGHFASP-DQNSMLSQLASNPGMANL-HGAS 2389
             +    + +  SP    S+L   A +  +  L HGAS
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGAS 2633



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 120/535 (22%), Positives = 169/535 (31%), Gaps = 99/535 (18%)

Query: 1837 RTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQ--------PTPPNSMPPYLP 1888
            R+   G   G PSP   T     G+    P  PQP   P         P P    P    
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTN 2579

Query: 1889 RTQAAGPVSQ-----GKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMA 1943
             T A G         G ++G           +PP   PPPA       +   A  +  + 
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGIT 2639

Query: 1944 HVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQP 2003
                   P++ +  P T     GM     T    G  +PGM  +G+ Q     Q    Q 
Sbjct: 2640 S------PVEKREDPGT-----GMGSSLATAELPGTQDPGM--SGLSQTELEKQR---QR 2683

Query: 2004 QQLQSGMPRPAMMSVAQHGQPLNMAPQPGL----GQVGISPLKPGTVSQQALQNLLRTLR 2059
            Q+L+  + R  +       +    A   G     G  G  P  P      A + L R  +
Sbjct: 2684 QRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSP------AFEQLSRG-Q 2736

Query: 2060 SPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP--T 2117
            +P +  Q +   S++   P  L+                PI G    P      +PP   
Sbjct: 2737 TPFAGTQDKS--SLVGLPPSKLSG---------------PILGPGSFPSDDRLSRPPPPA 2779

Query: 2118 MPGQQGVHSNPAMQNMNPMQAGVQRA----GLPQQQPQQQLQPPMGGMSPQAQQMNMNHN 2173
             P    V+S    Q +   QA  QRA     LP QQ QQQL       +  + +  M+  
Sbjct: 2780 TPSSMDVNSR---QLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSAR 2836

Query: 2174 TMPSQFRDILRRQQM---MQQQQQQGAGPGIG-PGMANHNQFQQ----------PQGVGY 2219
              PS     L RQ +   +     +  GPG   PG A   QF +          P G  +
Sbjct: 2837 -FPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPF 2895

Query: 2220 PPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMS 2279
            P Q            Q+     + + P  L  E    L            G P Q     
Sbjct: 2896 PGQGPP---------QRPRFYPVSEDPHRLAPEGLRGLAV---------SGLPPQKPSAP 2937

Query: 2280 PQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQ 2334
            P   +  +   +PH +G  +P  L    R P      RP      +   P   P+
Sbjct: 2938 PAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPE 2992



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 67/317 (21%), Positives = 115/317 (36%), Gaps = 36/317 (11%)

Query: 666  PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI 725
            P+S  P  N   P+P      P P P    G     +M  + PQ          + Q  +
Sbjct: 981  PISPPPEANCTDPEPVPPMILP-PSPGSPVGPASPILMEPLPPQCS-------PLLQHSL 1032

Query: 726  VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPS 785
            VP+ +PP Q     A P ++  P+    ++   S++ +     +  ++ ++    P    
Sbjct: 1033 VPQNSPPSQCSPP-ALPLSVPSPLSPIGKVVGVSDEAEL---HEMETEKVSEPECPALEP 1088

Query: 786  SGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT 845
            S  +P+  + M   SCP  SP  P     S +     P   +        P   P P  T
Sbjct: 1089 SATSPLP-SPMGDLSCPAPSPA-PALDDFSGLGEDTAPLDGID------APGSQPEPGQT 1140

Query: 846  PPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAP 905
            P S+ ++   +  +  P    P  P       ++P  +QT     +   +Q +P  P AP
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTP-----MEVYPECKQT-AGQGSPCEEQEEPRAPVAP 1194

Query: 906  SADQ-------PQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTS 958
            +           +    SQ   +AS P     L  P P       ++S+E  VS   S +
Sbjct: 1195 TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPE---GGGSLSMELGVSTDVSPA 1251

Query: 959  STEVNSQAIAEKQPSQE 975
              E + +   +  P  +
Sbjct: 1252 RDEGSLRLCTDSLPETD 1268



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 54/201 (26%), Positives = 76/201 (37%), Gaps = 34/201 (16%)

Query: 1816 QQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPT-TPQTPQPTSQ 1874
            QQ Q +L Q Q         Q T     +  + +  P+TP    G+Q   +P     T  
Sbjct: 2811 QQQQQQLWQQQ---------QATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRL 2861

Query: 1875 PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPP--PAAVEMAMQI 1932
            P P  P   P        AGP    +    V     P     P  GPP  P    ++   
Sbjct: 2862 PGPGEPVPGP--------AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDP 2913

Query: 1933 QRAA-ETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQ- 1990
             R A E  R +A   +   P Q    P  P     ++P P T+GP+        PTG++ 
Sbjct: 2914 HRLAPEGLRGLA---VSGLPPQKPSAPPAPELNNSLHPTPHTKGPT-------LPTGLEL 2963

Query: 1991 -QQPPWS-QGGLPQPQQLQSG 2009
              +PP S + G P P  L++G
Sbjct: 2964 VNRPPSSTELGRPNPLALEAG 2984



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 5/68 (7%)

Query: 2267 QQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSS 2326
            +Q+ +P    P  P   + P+ A  P     ++P     +  +  PVPSP P +  P S+
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP----TEPLAEPPVPSPLPLASSPESA 4959

Query: 2327 -PSPRMQP 2333
             P PR +P
Sbjct: 4960 RPKPRARP 4967



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 923  SVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
            S P P  P  PP P  P   PA        +PP+    E+ ++ +AE      + + +  
Sbjct: 4907 SAPPPEEPSPPPSPLAP--SPA--------SPPTEPLVELPTEPLAEPPVPSPLPLASSP 4956

Query: 983  EVDQPEPADTQPEDISESK 1001
            E  +P+P    PE+  +S+
Sbjct: 4957 ESARPKPRARPPEEGEDSR 4975



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 5/73 (6%)

Query: 815  SHIHCPQLPQPALHQNSPSPVP-SRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGP 873
            S++   QL  P   + SP P P + +P    T P +     P    P P P P A  P  
Sbjct: 4899 SNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP-- 4956

Query: 874  QSQALHPPPRQTP 886
              ++  P PR  P
Sbjct: 4957 --ESARPKPRARP 4967



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 52/241 (21%), Positives = 86/241 (35%), Gaps = 45/241 (18%)

Query: 1847 LPSPTPATPTTP------TGQQPTTPQT--PQPTSQPQPTPPNSMPPYLPRTQAA---GP 1895
            L +P   TP +P      T  +P  P    P P S   P  P  M P  P+         
Sbjct: 973  LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL 1032

Query: 1896 VSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
            V Q     Q +PP  P +   PL     + +   + +   AE      H    ++  + +
Sbjct: 1033 VPQNSPPSQCSPPALPLSVPSPL-----SPIGKVVGVSDEAE-----LHEMETEKVSEPE 1082

Query: 1956 MPPMTPMA------PMG-MNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQS 2008
             P + P A      PMG ++ P  +  P+     G+G          + G  P+P Q   
Sbjct: 1083 CPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQ--- 1139

Query: 2009 GMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQ 2068
                P  ++    G P+ + P+       ++P+ P  V  +  Q          SP ++Q
Sbjct: 1140 ---TPGSLASELKGSPVLLDPEE------LAPVTPMEVYPECKQT-----AGQGSPCEEQ 1185

Query: 2069 Q 2069
            +
Sbjct: 1186 E 1186



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 104/502 (20%), Positives = 162/502 (32%), Gaps = 84/502 (16%)

Query: 476  QVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSM--L 533
            Q  Q+  Q Q     Q+ QQ  Q  Q  + +    A       G GVQT   L      L
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGL 3776

Query: 534  HSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFP 593
                + Q  ++ + +  P  GP      P+   + +Q H         H    + Q+   
Sbjct: 3777 MPPSSHQGLLVQQLSPQPPQGPQGMLG-PAQVAVLQQQHPGALGPQGPHRQVLMTQS--- 3832

Query: 594  TPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQ 653
                      R+ +    A++ +G              L+  ++   Q++ ++++    Q
Sbjct: 3833 ----------RVLSSPQLAQQGQG--------------LMGHRLVTAQQQQQQQQH---Q 3865

Query: 654  KQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLN 713
            +Q  +   AG+  +  +   + GQP+      G L            Q   ++  Q  L 
Sbjct: 3866 QQGSM---AGLSHLQQSLMSHSGQPKLSAQPMGSLQQL---------QQQQQLQQQQQLQ 3913

Query: 714  QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ 773
            Q  Q  + Q   + +Q    Q   Q  Q            ++QQ   Q Q   Q Q   Q
Sbjct: 3914 QQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQ 3973

Query: 774  GMNVTNIPLAPSSGQAPVSQAQMSSSSCPVN--SPIMPPGSQGSHIHCPQLPQPALHQNS 831
             M + N      S Q    Q        P         PG+ G     P L      QN+
Sbjct: 3974 QMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALG-----PTLLLTGKEQNT 4028

Query: 832  PSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTT 891
              P  S   T           + P+T    P+    A+   P+S A  P           
Sbjct: 4029 VDPAVSSEAT-----------EGPSTHQGGPL----AIGTTPESMATEPG---------- 4063

Query: 892  QLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQV 951
                +V+PSL         Q QP+ Q S+    P    P    Q  + L        GQ+
Sbjct: 4064 ----EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119

Query: 952  SNPPSTSSTEVNSQAIAEKQPS 973
                S SS+E +S      QPS
Sbjct: 4120 G---SGSSSEASSVPHLLAQPS 4138



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 26/119 (21%), Positives = 43/119 (36%), Gaps = 9/119 (7%)

Query: 1847 LPSPTPATPTTPTGQQPTTPQTPQPTSQPQ---PTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            L +P P  P+ P    P  P    P ++P    PT P + PP       A      +   
Sbjct: 4906 LSAPPPEEPSPPPS--PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963

Query: 1904 QVTPPTPPQTAQPP----LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPP 1958
            +  PP   + ++PP      G     + + + IQ+ +  Q     V  F   +   + P
Sbjct: 4964 RARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRP 5022



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 63/265 (23%), Positives = 93/265 (35%), Gaps = 21/265 (7%)

Query: 76   SKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAG-LTSP 134
            S H+ L     S   P    G+ GP QV   Q QQ    LG      +  MTQ+  L+SP
Sbjct: 3780 SSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQ-QQHPGALGPQGPHRQVLMTQSRVLSSP 3838

Query: 135  NM---GMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQV 191
             +   G G  G      Q          Q +M   + +        L + +GQ  +  Q 
Sbjct: 3839 QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS-----LMSHSGQPKLSAQP 3893

Query: 192  MNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPN 251
            M GS+   + +Q +Q            L +  Q    Q+  Q   +  Q  +   +    
Sbjct: 3894 M-GSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ 3952

Query: 252  PYGSPYTQNPGQQIGASG----LGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA 307
                   Q   QQ         +GL  Q++T+LS    P    ++ V  G  P M  +P 
Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLS----PQQQQQQQVALG--PGMPAKPL 4006

Query: 308  PQVQQPGLVTPVAQGMGSGAHTADP 332
                 PG + P     G   +T DP
Sbjct: 4007 QHFSSPGALGPTLLLTGKEQNTVDP 4031


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 81/334 (24%), Positives = 133/334 (39%), Gaps = 67/334 (20%)

Query: 821  QLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHP 880
            Q+PQ  +    P+P            P+ GAQ      + A     PA P     Q++ P
Sbjct: 139  QMPQEEVELLPPAPKGKGRK------PAAGAQSAGTQQVAAVSSVSPATP----FQSVPP 188

Query: 881  PPRQTPTPPTTQLPQQVQ--PSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPAT 938
               QTP    T +P       S+P  P               AA+ P P  P++P  P T
Sbjct: 189  TVSQTPVIAATPVPTITANVTSVPVPP---------------AAAPPPPATPIVPVVPPT 233

Query: 939  P--LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPED 996
            P  + +  V  +   + P +++ T   S++       ++ K+ A+ E     P     +D
Sbjct: 234  PPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRE-SGGRPIKPPKKD 292

Query: 997  ISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQ 1056
            + + +V                                 Q +   G+  + +   + + +
Sbjct: 293  LEDGEVP--------------------------------QHAGKKGKLSEHLRYCDSILR 320

Query: 1057 ALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQ 1116
             ++    A Y     + PF +PVD + L + DY DI+K PMDLST+KRK+D  +Y +   
Sbjct: 321  EMLSKKHAAY-----AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375

Query: 1117 YVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFE 1150
            +  D+ LMF+N + YN     V     KL +VFE
Sbjct: 376  FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 409



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 3/131 (2%)

Query: 1030 PSTSATQSSPAPGQSK--KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP 1087
            P+T    + P P  S   K   K  +L+      ++ L++    + PF QPVD   L +P
Sbjct: 13   PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQ-FAWPFYQPVDAIKLNLP 71

Query: 1088 DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSE 1147
            DY  I+K+PMD+ TIK++L+   Y    + + D   MF N ++YN+ T  +      L +
Sbjct: 72   DYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK 131

Query: 1148 VFEQEIDPVMQ 1158
            +F Q++  + Q
Sbjct: 132  IFLQKVAQMPQ 142



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 38/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%)

Query: 1830 RRMASMQRTGVVGQQQGLPSPTPATP---TTPT-GQQPTTPQTPQPT------SQPQP-- 1877
            R+ A+  ++    Q   + S +PATP     PT  Q P    TP PT      S P P  
Sbjct: 157  RKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPA 216

Query: 1878 -TPPNSMPPYLPRTQAAGPVSQGKA----AGQVTPPTPPQTAQ-----PPLPGPPPAAV 1926
              PP    P +P      PV + K     A   TP T   TA      PPL  P  A V
Sbjct: 217  AAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKV 275



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 2233 QMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSP 2292
            QM Q  +  +   P+  G +  A  Q+       QQ+ +    +P +P Q + P  +Q+P
Sbjct: 139  QMPQEEVELLPPAPKGKGRKPAAGAQSAGT----QQVAAVSSVSPATPFQSVPPTVSQTP 194

Query: 2293 HLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQP 2335
             +    +P   +N    P P   P     PP +   P + P P
Sbjct: 195  VIAATPVPTITANVTSVPVP---PAAAPPPPATPIVPVVPPTP 234


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 89.0 bits (219), Expect = 5e-17
 Identities = 172/701 (24%), Positives = 243/701 (34%), Gaps = 175/701 (24%)

Query: 1844 QQGLP----SPTPATPTTPTGQQPTTPQTPQPTSQPQPTP------PNSMPPYLP----- 1888
            QQ +P       P  P TP     +TP    P SQP P P      P S PP LP     
Sbjct: 268  QQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPP 327

Query: 1889 -------RTQAAGPVSQGKAAGQVTPPTP-PQTAQPPLP--GPPPAAVEMAMQIQRAAET 1938
                      + G  S G   G   P TP   TA  PLP  G P +A   A+  + AA  
Sbjct: 328  EDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPG 387

Query: 1939 QRQMAHV---QIFQRPIQHQMPPMTPMAPM------GMNPPPMTRGPSGHL----EPGMG 1985
              Q + V    + +  ++H+   +  +  +           P  +GP G       P   
Sbjct: 388  NGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQA 447

Query: 1986 PTGMQQQPPWSQGGLPQPQ--------QLQSGMPRPAMMSVAQH------GQPLNMAPQP 2031
            P   QQ P     GL + +        Q QS    P    V  H      GQ +NM  Q 
Sbjct: 448  PPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPPGGDMGQQMNMMIQ- 506

Query: 2032 GLGQVGISPLKPGTVSQQALQNLLRTLR---------SPSSPLQQQQVLSIL-------- 2074
               ++G   L P  V+ + LQ      +           S PLQ    +  +        
Sbjct: 507  ---RLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGMMVRGPPPP 563

Query: 2075 -HANP--QLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQ-PGLQPPTMPGQQGVHSNPAM 2130
             H+ P  Q       Q        +P  + G P  P  + PG Q   +PG  G+ S P  
Sbjct: 564  YHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMPME 623

Query: 2131 QNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMP-------------S 2177
              MN MQ  V R G+   +      PPMGG S      N   NTMP              
Sbjct: 624  VPMNAMQRPV-RPGMGWTED----LPPMGGPS------NFAQNTMPYPGGQGEAERFMTP 672

Query: 2178 QFRDILRRQQMMQQ-----QQQQG-AGPGIGPGMANHNQFQ------------------- 2212
            + R+ L R Q++++     Q+  G AG G+G  M      Q                   
Sbjct: 673  RVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEG 732

Query: 2213 ---QPQGVGY--------PPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQ 2261
                P G+ +        PP  Q  ++     M  GN+     +   +       +   Q
Sbjct: 733  LAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQ 792

Query: 2262 QRLLQQQMGSP---VQPNPMSPQ-----------------QHML-----PNQAQSPHLQG 2296
            Q L+ Q+M  P   + P  +SP+                 Q ML     PNQ Q     G
Sbjct: 793  QMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGG 852

Query: 2297 QQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ---TSSPHPGL-- 2351
            Q    ++S  + + Q + SP   S P  +  + R+   P P   +P     S+P+ GL  
Sbjct: 853  QGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGR 912

Query: 2352 ----VAAQANPM---EQGHFASPDQNSMLSQLASNPGMANL 2385
                +    N M     GH  SP  + + S L ++P  ANL
Sbjct: 913  RPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPS-ANL 952



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 179/699 (25%), Positives = 242/699 (34%), Gaps = 168/699 (24%)

Query: 1813 LRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPT 1872
            L ++QL+HR +  Q LR     + R+G          P    P    G+     Q P P 
Sbjct: 399  LSKEQLEHRERSLQTLRDIERLLLRSGET-------EPFLKGPPGGAGEGGPPAQAPPPP 451

Query: 1873 SQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPA---AVEMA 1929
             QP   PP+ +  Y    Q+   +SQ ++ G   PP      +  +PG PP      +M 
Sbjct: 452  QQPPTAPPSGLKKYEEPLQSM--ISQTQSLG--GPP-----LEHEVPGHPPGGDMGQQMN 502

Query: 1930 MQIQRAAETQRQMAHVQIFQRPIQ----------------HQMPPMTPMAPMG-----MN 1968
            M IQR    Q  +   Q+  R +Q                H   P+  M  MG       
Sbjct: 503  MMIQRLG--QDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMMGMGGMMVRGP 560

Query: 1969 PPPMTRGPSGHLEPGM-----GPTGMQQQPPWSQGGLPQP------QQLQ--------SG 2009
            PPP    P     PGM     GP  + Q P   +GG P P       Q+Q          
Sbjct: 561  PPPYHSKPGDQWPPGMGAQLRGPMDV-QDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQS 619

Query: 2010 MPRPAMMSVAQH---------------GQPLNMA----PQPGLGQVGISPLKPGTVSQQA 2050
            MP    M+  Q                G P N A    P PG GQ          V ++ 
Sbjct: 620  MPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPG-GQGEAERFMTPRVREEL 678

Query: 2051 LQNLLRTLRS--PSSPL--------QQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI 2100
            L++ L   RS     PL        Q  ++  ++ A+ Q+  A    + A        P+
Sbjct: 679  LRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPM 738

Query: 2101 -------PGQPGMPQGQPGLQ---PPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP 2150
                    G    P GQ GL+   PP  PG   ++ N  M NMN M   VQ     Q   
Sbjct: 739  GMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNM-NMN-MNLNVQMTPQQQMLM 796

Query: 2151 QQQLQPP---MG--GMSPQAQQMNMNHNT-----------MPSQFRDILRRQQMMQQQQQ 2194
             Q+++ P   MG  G+SP+        N+           MPSQF            Q Q
Sbjct: 797  SQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQF----------PNQGQ 846

Query: 2195 QGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQH-------HMQQMQQGN-MGQIGQLP 2246
            QG   G GP  A        Q +  P Q    M +       HM      N  G +   P
Sbjct: 847  QGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAP 906

Query: 2247 QALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP---QQHMLPNQAQSPHLQGQQIPNSL 2303
                   G   +     +   QMGSP   +  SP   Q H     + S +L+  Q P+ +
Sbjct: 907  -----NRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQM 961

Query: 2304 SNQVRSPQPVPSPRPQ-------SQPPHSSPSPRMQPQ---PSPHHV-SPQTSSPHPGLV 2352
                 +  P P   PQ        + P  SPS    P    PSP  V SP+T+ P PG+ 
Sbjct: 962  VPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVS 1021

Query: 2353 AAQANP-----------MEQGHFASPDQNSMLSQLASNP 2380
              +  P           MEQG        S  S   +NP
Sbjct: 1022 QNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANP 1060



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 195/876 (22%), Positives = 293/876 (33%), Gaps = 155/876 (17%)

Query: 151  TGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNP 210
            +GM  S   +  M  +  M+  M PG +A G G    P   M    G GRG  +     P
Sbjct: 700  SGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTP---MGMEFGGGRGLLS-----P 751

Query: 211  GMGSAG-NLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASG 269
             MG +G   +  P+  G+  M     +     L + M        S   + PG  +G  G
Sbjct: 752  PMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQG 811

Query: 270  LGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHT 329
            L  +   +    N+       +K +     PN GQQ     Q P     ++Q MG+    
Sbjct: 812  LSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGGQGP--YQAMSQDMGNTQDM 869

Query: 330  ADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ 389
              P+                             Q ++P        L+HM    +     
Sbjct: 870  FSPD-----------------------------QSSMPMSNVGTTRLSHMPLPPASNPPG 900

Query: 390  VAHCASSRQIISHWKNCT----RHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSS--- 442
              H A +R +     + T    +   P    LK+    +   P++T     L +P +   
Sbjct: 901  TVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQ 960

Query: 443  -LGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQ----MPTQPQVQAKNQQNQQPG 497
             + +   + P      Q+  SS+    +  G P ++      +P+   V +       PG
Sbjct: 961  MVPLPSANPPGPLKSPQVLGSSLS-VRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPG 1019

Query: 498  QSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVP-SLGPM 556
             S Q  +P  NM++S    N   G   PS    S      N  + +M  N S+P +  P 
Sbjct: 1020 VS-QNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLM--NPSLPFTSSPD 1076

Query: 557  PTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVE 616
            PT +Q   + +  Q  +         L H  ++ I  T D   L DR    L+      +
Sbjct: 1077 PTPSQNPLSLMMTQMSK-YAMPSSTPLYHNAIKTI-ATSDDELLPDRP---LLPPPPPPQ 1131

Query: 617  GDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMG 676
            G     +N++    HL                 +   +  M  N  G  P+S  P P M 
Sbjct: 1132 GSGPGISNSQPSQMHL----------------NSAAAQSPMGMNLPGQQPLSHEPPPAML 1175

Query: 677  QPQPGMTSNGPL-PDPSMIRGSVPNQMMPRITPQSGLN-QFGQM--SMAQPPIVPRQTPP 732
                 + SN PL P+     G   N MM        LN   G +  S    P  PR   P
Sbjct: 1176 PSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQP 1235

Query: 733  LQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792
               HG +A  G      G GP +QQ    G  LP    P+Q             G  P  
Sbjct: 1236 ---HGAMAPTGG----GGGGPGLQQHYPSGMALPPEDLPNQ-----------PPGPMPPQ 1277

Query: 793  QAQMSSSSCPVNSPIMPPG---SQGSHIHCPQL-----------PQPALHQNSPSPVPSR 838
            Q  M  +         PPG      S ++ P+L           P+  L +  PS  PS 
Sbjct: 1278 QHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSS 1337

Query: 839  T----PTPHHTPPSIGAQQPP-------ATTIPAPVPTPPAMPPGPQS-------QALHP 880
            T    P   + PP     QPP          +    P+ P   PG Q           HP
Sbjct: 1338 TLQYFPKSENQPPK---AQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLNMSMCHP 1394

Query: 881  PPR----QTPTPPTT-QLPQQVQPSLPAAPSADQPQQ-----QPRSQQSTAASVP----T 926
                   +T  PP    +P  +   + + P     QQ     + R       S P    +
Sbjct: 1395 GQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYSQPPHMLS 1454

Query: 927  PTAPLLPPQP------ATPLSQPAVSIEGQVSNPPS 956
            P   L+ P P      + PL Q +VS++ Q+   P+
Sbjct: 1455 PQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPA 1490



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 117/464 (25%), Positives = 162/464 (34%), Gaps = 94/464 (20%)

Query: 1849 SPTPATPTTPTG-QQPTTPQTPQPTSQPQPTP-------------PNSMPPY--LPRTQA 1892
            S  PA P  P+G   P+ P T  P   P   P             P+S P Y    +T A
Sbjct: 1054 SAPPANP--PSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIA 1111

Query: 1893 AGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPI 1952
                        + PP PPQ + P +    P+ + +      +A  Q  M      Q+P+
Sbjct: 1112 TSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHL-----NSAAAQSPMGMNLPGQQPL 1166

Query: 1953 QHQMPP-MTPM-APMGMNPP--PMTRGPSGHLEPGM-----GPTGMQQQ---PPWSQGGL 2000
             H+ PP M P   P+G N P  P  +G  G  +  M     GP  +       P S   +
Sbjct: 1167 SHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMM 1226

Query: 2001 PQPQQLQSGMPRPAMMSVA--------QHGQPLNMA-PQPGLGQVGISPLKPGT-VSQQA 2050
            P P +LQ   P  AM            Q   P  MA P   L      P+ P   +  +A
Sbjct: 1227 PFPPRLQQ--PHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKA 1284

Query: 2051 LQNLLRTLRSP------SSPLQQQQVLSILHANPQLLAAFIKQRAAK----------YAN 2094
            +   +     P      +S L   ++  ++   P  +  F   R             +  
Sbjct: 1285 MAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPK 1344

Query: 2095 SNPQPIPGQP---------GMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAG-VQRAG 2144
            S  QP   QP          M   Q   +PP +PGQQGV     M   +P Q   + R G
Sbjct: 1345 SENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTG 1404

Query: 2145 LPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPG 2204
            +P QQ         G MSP    M                 QQ     +Q+G G   G  
Sbjct: 1405 VPPQQGMVPHGLHQGVMSPPQGLMT----------------QQNFMLMKQRGVG---GEV 1445

Query: 2205 MANHNQFQQPQG--VGYPPQQQQRMQHHMQQMQQGNMGQIGQLP 2246
             +       PQG  +G PPQQ   + H ++Q       Q+G LP
Sbjct: 1446 YSQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLP 1489



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 241/1134 (21%), Positives = 374/1134 (32%), Gaps = 204/1134 (17%)

Query: 10   PPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTSL- 68
            PP    P  + PAL          G   D   DL    + +   G   GG      T+  
Sbjct: 308  PPPPPAPGSAPPALPPE-------GPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATT 360

Query: 69   -------GMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSM 121
                   G    +A     L E    G+     +G  G  +      ++S   L  I  +
Sbjct: 361  ANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERL 420

Query: 122  V-KSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNP--GML 178
            + +S  T+  L  P  G G  GP   P Q+      P  QP     +G+     P   M+
Sbjct: 421  LLRSGETEPFLKGPPGGAGEGGP---PAQAP----PPPQQPPTAPPSGLKKYEEPLQSMI 473

Query: 179  AAGNGQGIMP--NQVMNGSIGAGRGRQ-NMQYPNPGMGS------AGNLLTEPLQQGSPQ 229
            +     G  P  ++V     G   G+Q NM     G  S      A   L E   +   +
Sbjct: 474  SQTQSLGGPPLEHEVPGHPPGGDMGQQMNMMIQRLGQDSLTPEQVAWRKLQEEYYEEKRR 533

Query: 230  MGGQTGLRGPQPLK----MG--MMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNN 283
               Q GL G +PL+    MG  M+  P P   PY   PG Q    G+G Q++    + + 
Sbjct: 534  KEEQIGLHGSRPLQDMMGMGGMMVRGPPP---PYHSKPGDQ-WPPGMGAQLRGPMDVQDP 589

Query: 284  LS-----PFAMDK------KAVPG-GGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHTAD 331
            +      PF   +      + VPG GGM +M  +    V    +  PV  GMG       
Sbjct: 590  MQLRGGPPFPGPRFPGNQIQRVPGFGGMQSMPME----VPMNAMQRPVRPGMG-WTEDLP 644

Query: 332  PEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVA 391
            P        Q  +     + +        VR+  L H    K  +          S    
Sbjct: 645  PMGGPSNFAQNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQ 704

Query: 392  HCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSAP 451
                 R + +H     R   P   P + AG +      L G P+G+      G G  S P
Sbjct: 705  SMEMERMMQAH-----RQMDPAMFPGQMAGGEG-----LAGTPMGMEFGG--GRGLLSPP 752

Query: 452  -NLSTVSQIDP-----SSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQ--SPQGM 503
               S + ++DP     +        + +   +N   T  Q    +Q+ + PG    PQG+
Sbjct: 753  MGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGL 812

Query: 504  RPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPS 563
             P           +G +G     L+          SQ P   +       GP    +Q  
Sbjct: 813  SPEEMARVRAQNSSGVMGGPQKMLMP---------SQFPNQGQQGFSGGQGPYQAMSQDM 863

Query: 564  TTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD--PAALKDRRMENLVAYARKVEGDMYE 621
                     +  +  + N    +L     P     P  +       L     +   D+  
Sbjct: 864  GNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGL----GRRPSDLTI 919

Query: 622  SANNRAE--YYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQ 679
            S N        HL +  + ++   L       L K    P+    +P +  PGP +  PQ
Sbjct: 920  SINQMGSPGMGHLKSPTLSQVHSPLVTSPSANL-KSPQTPSQMVPLPSANPPGP-LKSPQ 977

Query: 680  ---PGMTSNGPLPDPSMIRGSVPNQMMPR----ITPQSGLNQFGQMSMAQPPIVPRQTPP 732
                 ++   P   PS ++   P+  +P      +P++ +   G     QPP+    +  
Sbjct: 978  VLGSSLSVRSPTGSPSRLKS--PSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTT 1035

Query: 733  LQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792
            L +  Q    G L P    GPR    +      P +   +  +  T+ P  P+  Q P+S
Sbjct: 1036 LSNMEQ----GTLPPS---GPRSSSSAPPAN--PPSGLMNPSLPFTSSP-DPTPSQNPLS 1085

Query: 793  --QAQMSSSSCPVNSPIM-----------------------PPGSQGSHIHCPQLPQPAL 827
                QMS  + P ++P+                        PP  QGS           +
Sbjct: 1086 LMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQM 1145

Query: 828  HQNSPSPV-PSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT- 885
            H NS +   P     P   P S    +PP   +P+P P    +P  P +Q    PP+ + 
Sbjct: 1146 HLNSAAAQSPMGMNLPGQQPLS---HEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQNSM 1202

Query: 886  ------------------------PTPPTTQLP----------------QQVQPS----- 900
                                    P PP  Q P                QQ  PS     
Sbjct: 1203 MMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALP 1262

Query: 901  ---LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPST 957
               LP  P    P QQ    ++ A  +     P + P  A+ L+ P +S   +V  P  T
Sbjct: 1263 PEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELS---EVIRPTPT 1319

Query: 958  SSTEVN-SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMEST 1010
               E + S+ I  ++PS  ++   K E    +P   QP ++    +++   E T
Sbjct: 1320 GIPEFDLSRIIPSEKPSSTLQYFPKSE---NQPPKAQPPNLHLMNLQNMMAEQT 1370



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 118/517 (22%), Positives = 174/517 (33%), Gaps = 112/517 (21%)

Query: 1833 ASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPN----------- 1881
            +S+      G    L SP+ A P+      P T       SQ +  P N           
Sbjct: 981  SSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNME 1040

Query: 1882 --SMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ 1939
              ++PP  PR+ ++ P +    +G + P  P  ++  P P   P ++ M    + A  + 
Sbjct: 1041 QGTLPPSGPRSSSSAPPAN-PPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSS 1099

Query: 1940 RQMAHVQIF-----------QRPIQHQMPPMTPMAPMGMNPPPM--------TRGPSGHL 1980
              + H  I             RP+    PP     P   N  P          + P G  
Sbjct: 1100 TPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMN 1159

Query: 1981 EPGMGPTGMQQQPPWSQGGLPQPQQLQS------------GMPRPAMMSVAQHGQPLNMA 2028
             PG  P  +  +PP +   LP P  L S            G P+ +MM        LN  
Sbjct: 1160 LPGQQP--LSHEPPPAM--LPSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAP 1215

Query: 2029 PQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQR 2088
              P      + P  P    QQ    +  T      P  QQ   S +   P+ L       
Sbjct: 1216 CGPVPSSSQMMPFPPRL--QQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLP------ 1267

Query: 2089 AAKYANSNPQPIPGQPGMP----QGQPG--LQPPTMPGQQGVHSNPAMQNM-NPMQAGVQ 2141
                 N  P P+P Q  +      G+ G    P  +PG   V ++P +  +  P   G+ 
Sbjct: 1268 -----NQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIP 1322

Query: 2142 RAGL----PQQQPQQQLQ--PPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQ-- 2193
               L    P ++P   LQ  P      P+AQ  N++          ++  Q MM +Q   
Sbjct: 1323 EFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLH----------LMNLQNMMAEQTPS 1372

Query: 2194 -------QQGAGPGIGPGMANHNQF----------QQP-------QGVGYPPQQQQRMQH 2229
                   QQG   G+   M +  Q           QQ        QGV  PPQ     Q+
Sbjct: 1373 RPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQN 1432

Query: 2230 HMQQMQQGNMGQI-GQLPQALGAEAGASLQAYQQRLL 2265
             M   Q+G  G++  Q P  L  +        QQ L+
Sbjct: 1433 FMLMKQRGVGGEVYSQPPHMLSPQGSLMGPPPQQNLM 1469



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 124/574 (21%), Positives = 192/574 (33%), Gaps = 89/574 (15%)

Query: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQ-PQPTPPNSMPPYLPRTQAAGPVSQGKAAG---Q 1904
            SP      +PT  Q  +P    P++    P  P+ M P LP     GP+   +  G    
Sbjct: 926  SPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVP-LPSANPPGPLKSPQVLGSSLS 984

Query: 1905 VTPPT--PPQTAQPPLPGPPP---AAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
            V  PT  P +   P +  P P   A+ + AM     ++ ++   ++         +   +
Sbjct: 985  VRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTL 1044

Query: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVA 2019
             P  P   +  P    PSG + P +         P++    P P Q    +    M  ++
Sbjct: 1045 PPSGPRSSSSAPPANPPSGLMNPSL---------PFTSSPDPTPSQNPLSL---MMTQMS 1092

Query: 2020 QHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQ 2079
            ++  P +            +PL           N ++T+ +    L   + L      PQ
Sbjct: 1093 KYAMPSS------------TPL---------YHNAIKTIATSDDELLPDRPLLPPPPPPQ 1131

Query: 2080 LLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMN-PMQA 2138
                 I        + N        GM    PG QP +      +  +P     N P+  
Sbjct: 1132 GSGPGISNSQPSQMHLNSAAAQSPMGM--NLPGQQPLSHEPPPAMLPSPTPLGSNIPLHP 1189

Query: 2139 GVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAG 2198
              Q  G P   PQ  +    GG  P +           SQ      R Q          G
Sbjct: 1190 NAQGTGGP---PQNSMMMAPGG--PDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGG 1244

Query: 2199 PGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQ 2258
             G GPG+  H     P G+  PP+            QQ  MG+         A AG    
Sbjct: 1245 GGGGPGLQQH----YPSGMALPPEDLPNQPPGPMPPQQHLMGK---------AMAGRMGD 1291

Query: 2259 AYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPS--- 2315
            AY   +L    G     N     + + P     P          LS  + S +P  +   
Sbjct: 1292 AYPPGVLP---GVASVLNDPELSEVIRPTPTGIPEF-------DLSRIIPSEKPSSTLQY 1341

Query: 2316 -PRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQG---HFASPDQNS 2371
             P+ ++QPP + P P +      + ++ QT S  P L   Q   +++G       P Q S
Sbjct: 1342 FPKSENQPPKAQP-PNLHLMNLQNMMAEQTPSRPPNLPGQQG--VQRGLNMSMCHPGQMS 1398

Query: 2372 MLSQLASNP--GMA--NLH-GASATDLGLSTDNS 2400
            +L +    P  GM    LH G  +   GL T  +
Sbjct: 1399 LLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQN 1432



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 117/574 (20%), Positives = 179/574 (31%), Gaps = 81/574 (14%)

Query: 1798 ENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQR-TGVVGQQQGLPSPTPATPT 1856
            +N  P P      ++    +++  L + Q+L +R   MQR  G+ G              
Sbjct: 654  QNTMPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAG-------------- 699

Query: 1857 TPTGQQPTTPQTPQPTSQPQPTP-PNSMPPYLPRTQAAGPVSQGKAAGQVTPP---TPPQ 1912
            +  GQ     +  Q   Q  P   P  M            +  G   G ++PP   +  +
Sbjct: 700  SGMGQSMEMERMMQAHRQMDPAMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLR 759

Query: 1913 TAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPM 1972
               PP+ GP    + M + +        QM   Q      Q    P   M P G++P  M
Sbjct: 760  EVDPPM-GPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMS-QKMRGPGDLMGPQGLSPEEM 817

Query: 1973 TR-----------GPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQH 2021
             R           GP   L P   P   Q Q  +S G  P     Q       M S  Q 
Sbjct: 818  ARVRAQNSSGVMGGPQKMLMPSQFPN--QGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQS 875

Query: 2022 GQPLNMAPQPGLGQVGISPLK--PGTVSQQALQNL----------LRTLRSPSSPLQQQQ 2069
              P++      L  + + P    PGTV     + L          +  + SP     +  
Sbjct: 876  SMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSP 935

Query: 2070 VLSILHA------NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQG 2123
             LS +H+      +  L +     +     ++NP      P +      ++ PT  G   
Sbjct: 936  TLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPT--GSPS 993

Query: 2124 VHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDIL 2183
               +P+M   +P      +  +P     Q  QPP+  M+      NM   T+P       
Sbjct: 994  RLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPL-NMNSSTTLSNMEQGTLPP------ 1046

Query: 2184 RRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIG 2243
                     +   + P   P     N          P   Q  +   M QM +  M    
Sbjct: 1047 ------SGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPS-- 1098

Query: 2244 QLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSL 2303
                 L   A  ++      LL  +   P+ P P  P       Q   P +   Q     
Sbjct: 1099 --STPLYHNAIKTIATSDDELLPDR---PLLPPPPPP-------QGSGPGISNSQPSQMH 1146

Query: 2304 SNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP 2337
             N   +  P+    P  QP    P P M P P+P
Sbjct: 1147 LNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTP 1180



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 112/506 (22%), Positives = 170/506 (33%), Gaps = 78/506 (15%)

Query: 620  YESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQ 679
            Y      AE +     +   ++ +L EKR   +Q+           P+ M  G  MGQ  
Sbjct: 659  YPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQR-----------PLGM-AGSGMGQSM 706

Query: 680  P--GMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI----VPRQTPPL 733
                M       DP+M  G +        TP  G+   G   +  PP+    +    PP+
Sbjct: 707  EMERMMQAHRQMDPAMFPGQMAGGEGLAGTPM-GMEFGGGRGLLSPPMGQSGLREVDPPM 765

Query: 734  QHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQ 793
                    PG LN  M     M    N      Q    SQ M      + P  G +P   
Sbjct: 766  G-------PGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDLMGPQ-GLSPEEM 817

Query: 794  AQM--SSSSCPVNSP---IMPP-----GSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPH 843
            A++   +SS  +  P   +MP      G QG      Q P  A+ Q+  +     +P   
Sbjct: 818  ARVRAQNSSGVMGGPQKMLMPSQFPNQGQQG--FSGGQGPYQAMSQDMGNTQDMFSPDQS 875

Query: 844  HTPPSIGAQQPPATTIPAPVPTPPAM-PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSL- 901
              P S        TT  + +P PPA  PPG    A +    + P+  T  + Q   P + 
Sbjct: 876  SMPMS-----NVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMG 930

Query: 902  ----PAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPST 957
                P       P     S    +   P+   PL    P  PL  P V         P+ 
Sbjct: 931  HLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTG 990

Query: 958  SSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERST 1017
            S + + S ++A   P           V  P+ A   P  +S++K     M S+ T     
Sbjct: 991  SPSRLKSPSMAVPSPGW---------VASPKTAMPSP-GVSQNKQPPLNMNSSTTLSN-- 1038

Query: 1018 ELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQ 1077
                   E+   P +    SS AP  +      P  L    +P     +   P+  P + 
Sbjct: 1039 ------MEQGTLPPSGPRSSSSAPPAN-----PPSGLMNPSLP-----FTSSPDPTPSQN 1082

Query: 1078 PVDPQLLGIPDYFDIVKSPMDLSTIK 1103
            P+   +  +  Y     +P+  + IK
Sbjct: 1083 PLSLMMTQMSKYAMPSSTPLYHNAIK 1108



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 66/258 (25%), Positives = 95/258 (36%), Gaps = 44/258 (17%)

Query: 719 SMAQPPIVPRQTPPLQHHGQLAQPGALN-PPMGYGPRMQQPSNQGQFLPQTQFPSQGMNV 777
           +MA P + P QT  L    + + PGA + PP G  P        G  +P    PSQ + V
Sbjct: 185 AMAAPQLGPGQTTQLPL-SESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKP-PSQFVYV 242

Query: 778 TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPS 837
               LA ++ +A V Q +  S                   H   +P+  L Q      P 
Sbjct: 243 FTTHLANTAAEA-VLQGRADSILA---------------YHQQNVPRAKLDQ-----APK 281

Query: 838 RTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQV 897
             PTP                 P P+ TP A  P  Q   L PPP   P      LP + 
Sbjct: 282 VPPTPE----------------PLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEG 325

Query: 898 QP---SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLP-PQPATPLSQPAVSIEGQVSN 953
            P   S   AP++            T  + PT T    P P    P S P  ++ G+ + 
Sbjct: 326 PPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAA 385

Query: 954 PPSTSSTEVNSQAIAEKQ 971
           P +   + V S+ ++++Q
Sbjct: 386 PGNGQRSLVGSEGLSKEQ 403



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 12/77 (15%)

Query: 2285 LPNQAQSPHLQG----------QQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQ 2334
            L N A    LQG          Q +P +  +Q     P P P P S P  S+ +P+ QP 
Sbjct: 247  LANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTP--SAGTPQSQPP 304

Query: 2335 PSPHHVSPQTSSPHPGL 2351
            P P    P   S  P L
Sbjct: 305  PLPPPPPPAPGSAPPAL 321


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 131/528 (24%), Positives = 199/528 (37%), Gaps = 109/528 (20%)

Query: 1902 AGQVTPPTPPQTAQPPLPGPPPAAVEMA-----------------MQIQRAAETQRQMAH 1944
            AG+ +PP  P     P    P  A  +A                 ++ +R A+ ++ +A 
Sbjct: 2435 AGKRSPPIKPLLGMNPFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALAD 2494

Query: 1945 VQIFQRPIQHQMPPMTPMAPMGMN--PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQ 2002
             Q  Q+P   Q PP  P  P      PPP+ +  +   +P  GP  +Q QP       PQ
Sbjct: 2495 QQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQ 2554

Query: 2003 PQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPS 2062
            P Q     P  A  ++   G    +A        G S +  G VS   + N +  +  P+
Sbjct: 2555 PVQ----APAKAQPAITTGGSAAVLAGTIKTSVTGTS-MPTGAVSGNVIVNTIAGV--PA 2607

Query: 2063 SPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP---TMP 2119
            +  Q           P  L        A+  ++ P P         G P    P   +M 
Sbjct: 2608 ATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPP------RAVGSPATATPDLVSMA 2661

Query: 2120 GQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179
              QGV +  ++       A V     P Q P + L P +     QA  + +   T+    
Sbjct: 2662 TTQGVRAVTSV----TASAVVTTNLTPVQTPARSLVPQVS----QATGVQLPGKTITPAH 2713

Query: 2180 RDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNM 2239
              +LR+QQ  QQQQQQ                QQ Q      QQQQ+ Q   QQ Q    
Sbjct: 2714 FQLLRQQQQQQQQQQQ----------------QQQQ------QQQQQQQQQQQQQQTTTT 2751

Query: 2240 GQIGQLPQALG-AEAGASLQAYQQ-------RLLQQQMGSPVQPNPMSPQQHMLPNQAQS 2291
             Q+ Q+PQ  G A++ A ++A  +       ++ +Q++  P QP P  PQ    P Q  +
Sbjct: 2752 SQV-QVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPP--PQAQSAPPQPTA 2808

Query: 2292 PHLQGQQIPNSLSNQVRSPQ--PVPSPRPQSQPPHSS------------PSPRMQPQPSP 2337
                  Q+  S   Q +SPQ   V +PRP +    ++            P+ ++Q Q   
Sbjct: 2809 Q----VQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQG-- 2862

Query: 2338 HHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANL 2385
                 QT +P P  VA           A P   S+ + + S+PG+  L
Sbjct: 2863 ---QMQTQAPQPAQVA----------LAKPPVVSVPAAVVSSPGVTTL 2897



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 137/535 (25%), Positives = 191/535 (35%), Gaps = 95/535 (17%)

Query: 1847 LPSPT-PATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPY--LPRTQAAGPVSQGKAAG 1903
            L SP  P   TTP G  P      QP  +   +P  + P    +  TQ    V+   A+ 
Sbjct: 2617 LASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASA 2676

Query: 1904 QVTP-----PTP-----PQTAQP---PLPGP--PPAAVEMAMQIQRAAETQRQMAHVQIF 1948
             VT       TP     PQ +Q     LPG    PA  ++  Q Q+  + Q+Q    Q  
Sbjct: 2677 VVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQ 2736

Query: 1949 QRPIQHQMPPMTPMAP-------MGMNPPPMTRGPSGHLEP----GMGPTGMQQQPPWSQ 1997
            Q+  Q Q    T            G    P      G L P     M    +Q  P    
Sbjct: 2737 QQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQ--- 2793

Query: 1998 GGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQV-GISPLKPG---TVSQQALQN 2053
               P P Q QS  P+P      Q  QP    PQ    Q+  ++  +PG   T +  A   
Sbjct: 2794 ---PPPPQAQSAPPQPTAQVQVQTSQP----PQQQSPQLTTVTAPRPGALLTGTTVANLQ 2846

Query: 2054 LLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPG---MPQGQ 2110
            + R  R P+S LQ Q  +      P  +A      A     S P  +   PG   +P   
Sbjct: 2847 VARLTRVPTSQLQAQGQMQTQAPQPAQVAL-----AKPPVVSVPAAVVSSPGVTTLPMNV 2901

Query: 2111 PGL-----QPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQA 2165
             G+     QP    GQ  V     MQ         Q   L QQ  QQQ       + PQA
Sbjct: 2902 AGISVAIGQPQKAAGQTVVAQPVHMQ---------QLLKLKQQAVQQQ-----KAIQPQA 2947

Query: 2166 QQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQ 2225
             Q        P+  +  +  QQ+     QQ       P +       + Q +  P  Q Q
Sbjct: 2948 AQ-------GPAAVQQKITAQQITTPGAQQKVAYAAQPAL-------KTQFLTTPISQAQ 2993

Query: 2226 RMQHHMQQMQQGNMGQIGQLPQ------ALGAEAGASLQAYQQRLLQQQMGSPVQPNPMS 2279
            ++    Q   Q  + ++ Q+ Q      ++   A AS QA  Q +   Q  +  Q   M 
Sbjct: 2994 KLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMI 3053

Query: 2280 PQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQ 2334
            P         Q   +Q QQ+  + S  +++P   P+P   +Q P SS SP  QP+
Sbjct: 3054 PAVTATAQVVQQKLIQ-QQVVTTASAPLQTP-GAPNP---AQVPASSDSPSQQPK 3103



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 96/405 (23%), Positives = 141/405 (34%), Gaps = 70/405 (17%)

Query: 663  GMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQ 722
            GM P   NP       + G+  + PLP P  +      ++       +   +  Q ++AQ
Sbjct: 2447 GMNPFQKNPKHASVLAESGINYDKPLP-PIQVASLRAERIAKEKKALADQQKAQQPAVAQ 2505

Query: 723  PPIVPRQTPP--LQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNI 780
            PP    Q PP   Q    L QP A       GP   QP  Q Q  PQTQ           
Sbjct: 2506 PPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQ--PQTQPQPVQAPAKAQ 2563

Query: 781  PLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI------HCPQLPQPALHQNSPSP 834
            P   + G A V    + +S   V    MP G+   ++        P     ++++   SP
Sbjct: 2564 PAITTGGSAAVLAGTIKTS---VTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASP 2620

Query: 835  V-PSRTPTPH--------HTPPSIGAQQPPATTIP------------------------- 860
            V P    TP         HT P   A   PAT  P                         
Sbjct: 2621 VAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTT 2680

Query: 861  --APVPTPPAMPPGPQSQALHPP-PRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ 917
               PV TP        SQA     P +T TP   QL +Q Q          Q QQQ + Q
Sbjct: 2681 NLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQ 2740

Query: 918  QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVK 977
            Q       T T+ +  PQ           I+GQ  +P          +A+ +  P   +K
Sbjct: 2741 QQQQQQQTTTTSQVQVPQ-----------IQGQAQSPAQI-------KAVGKLTPEHLIK 2782

Query: 978  MEAKMEVDQPEPADTQPEDISESKVEDCKMESTE-TEERSTELKT 1021
            M+ +     P+P   Q +          ++++++  +++S +L T
Sbjct: 2783 MQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTT 2827



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 125/551 (22%), Positives = 172/551 (31%), Gaps = 103/551 (18%)

Query: 1861 QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTP-PQTAQPPLP 1919
            QQP   Q P P  QP P PP   PP LP+ QAAG  SQ  A      P P PQ    P P
Sbjct: 2499 QQPAVAQPPPPQPQP-PPPPQQPPPPLPQPQAAG--SQPPAGPPAVQPQPQPQPQTQPQP 2555

Query: 1920 GPPPAAVEMAMQIQRAAETQRQMAHVQI--------------------------FQRPIQ 1953
               PA  + A+    +A          +                          FQ   +
Sbjct: 2556 VQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINK 2615

Query: 1954 HQMPPMTPMA---PMG--------MNPPPMTRGPSGHLEPGMGPTGMQQ----------- 1991
                P+ P A   P G          PPP   G      P +      Q           
Sbjct: 2616 RLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS 2675

Query: 1992 ----------QPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPL 2041
                      Q P ++  +PQ  Q  +G+  P       H Q L    Q    Q      
Sbjct: 2676 AVVTTNLTPVQTP-ARSLVPQVSQ-ATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQ 2733

Query: 2042 KPGTVSQQALQNLLRTLRSPSSPLQQQ-------QVLSILHANPQLLAAFIKQRAAKYAN 2094
            +     QQ  Q    T  S     Q Q       Q+ ++    P+ L    KQ+      
Sbjct: 2734 QQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQK----LQ 2789

Query: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL 2154
              PQP P Q      QP  Q      Q     +P +  +   + G    G      Q   
Sbjct: 2790 MPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVAR 2849

Query: 2155 QPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMAN----HNQ 2210
               +     QAQ         P+Q    L +  ++       + PG+     N       
Sbjct: 2850 LTRVPTSQLQAQGQMQTQAPQPAQV--ALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVA 2907

Query: 2211 FQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMG 2270
              QPQ         Q +  HMQQ+ +    Q  Q  +A+  +A     A QQ++  QQ+ 
Sbjct: 2908 IGQPQKAAGQTVVAQPV--HMQQLLKLKQ-QAVQQQKAIQPQAAQGPAAVQQKITAQQIT 2964

Query: 2271 SP---------VQP--------NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ--VRSPQ 2311
            +P          QP         P+S  Q +   Q     +Q  ++P  +  Q  V S Q
Sbjct: 2965 TPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQ 3024

Query: 2312 PVPSPRPQSQP 2322
             V S   Q+ P
Sbjct: 3025 QVASASQQASP 3035



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 71/269 (26%), Positives = 101/269 (37%), Gaps = 31/269 (11%)

Query: 1814 RQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQ--QPTTPQTPQP 1871
            ++QQ       A+  +R    +   GVV Q  G  +  P     PT Q   P TPQ  Q 
Sbjct: 466  KRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQL 525

Query: 1872 TSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQ 1931
              Q Q     S   Y P T   GP  Q  A+  +  P P    + P  G P AA+  A+Q
Sbjct: 526  AGQRQ-----SQQQYDPST---GPPVQNAAS--LHTPLPQLPGRLPPAGVPTAALSSALQ 575

Query: 1932 IQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ 1991
              +  +       +QI   P++ Q P +   AP     P     P+  L   +   G  Q
Sbjct: 576  FAQQPQVVEAQTQLQI---PVKTQQPNVPIPAPPSSQLPIPPSQPA-QLALHVPTPGKVQ 631

Query: 1992 QPPWSQGGLPQ-------PQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPL-KP 2043
                    LPQ       P       PRP   S      P++    PG      SP+ +P
Sbjct: 632  VQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVS-GSGPGPSPARSSPVNRP 690

Query: 2044 GTVSQQALQNLLRTLRSP----SSPLQQQ 2068
             + + +AL  +  T R+P    S+P + Q
Sbjct: 691  SSATNKALSPV--TSRTPGVVASAPTKPQ 717



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 143/605 (23%), Positives = 199/605 (32%), Gaps = 114/605 (18%)

Query: 429 ILTGAPVGL---GNPSSLGVGQQSAPNLS---TVSQIDPSSIERAYAA----LGLPYQVN 478
           I  GA V L   G P ++   + S P+     T+  + P S   A  A    L  P  + 
Sbjct: 201 IAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGLQPLASPSHIT 260

Query: 479 QMPTQPQV----QAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLH 534
                PQ+    Q +  Q QQ  Q P   RP+       + + G  G     + S     
Sbjct: 261 TANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSPPPPT 320

Query: 535 SAINSQNPMMSENASVPSLG------------PMPTAAQPSTTGIRKQ---WHEDITQDL 579
           S   +  P    +  + S+G             +P A+ P    +RKQ   +H    Q L
Sbjct: 321 SPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPAS-PEMAQMRKQCLDYHYQEMQAL 379

Query: 580 RNHLVHKLVQAIF------PTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLL 633
           +      L++  F         D  A K +    L AY R+ + D+ E      E     
Sbjct: 380 KEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEEE---- 435

Query: 634 AEKIYKIQKELE----------EKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQP----- 678
            EK   I  E                T L K+     + GM   S  P   +G       
Sbjct: 436 EEKSEVINDEQALAGSLVAGAGSTVETDLFKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQ 495

Query: 679 QPGMTSNGPLPD--PSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQH- 735
            PG  +  PL    P+   G  P       TPQ+   Q      +Q    P   PP+Q+ 
Sbjct: 496 HPGADAGVPLQQLMPTAQGGMPP-------TPQAA--QLAGQRQSQQQYDPSTGPPVQNA 546

Query: 736 ---HGQLAQ-PGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPV 791
              H  L Q PG L P    G      S+  QF  Q Q          +  A +  Q PV
Sbjct: 547 ASLHTPLPQLPGRLPPA---GVPTAALSSALQFAQQPQ----------VVEAQTQLQIPV 593

Query: 792 SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGA 851
              Q        N PI  P S    I   Q  Q ALH  +P  V  +       P  + +
Sbjct: 594 KTQQP-------NVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVAS 646

Query: 852 QQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911
            + P    PAP                 P PR  PT  T+ L          +P+   P 
Sbjct: 647 TRLPVD--PAP-----------------PCPRPLPTSSTSSLAPVSGSGPGPSPARSSPV 687

Query: 912 QQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ 971
            +P S  + A S  T   P +     T    PA   +   S+  S+  T +  Q   E Q
Sbjct: 688 NRPSSATNKALSPVTSRTPGVVASAPTKPQSPA---QNATSSQDSSQDT-LTEQITLENQ 743

Query: 972 PSQEV 976
             Q +
Sbjct: 744 VHQRI 748



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 105/433 (24%), Positives = 157/433 (36%), Gaps = 55/433 (12%)

Query: 1807 LNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTP 1866
            L  +Q+ +QQQ Q + QQ Q  +++    Q+T    Q Q +P        +P   +    
Sbjct: 2717 LRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQ-VPQ-IQGQAQSPAQIKAVGK 2774

Query: 1867 QTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPL---PGPPP 1923
             TP+   + Q      MPP  P  QA     Q  A  QV    PPQ   P L     P P
Sbjct: 2775 LTPEHLIKMQ-KQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRP 2833

Query: 1924 AAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPM-APMGMNPPPMTRGPSGHL-E 1981
             A+     +  A     ++  V   Q   Q QM    P  A + +  PP+   P+  +  
Sbjct: 2834 GALLTGTTV--ANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSS 2891

Query: 1982 PGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPL 2041
            PG+    M         G PQ    Q+ + +P  M      Q L +  Q    Q  I P 
Sbjct: 2892 PGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQ-----QLLKLKQQAVQQQKAIQPQ 2946

Query: 2042 K---PGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIK---QRAAKYANS 2095
                P  V Q+       T +  ++P  QQ+V     A P L   F+     +A K A  
Sbjct: 2947 AAQGPAAVQQKI------TAQQITTPGAQQKV--AYAAQPALKTQFLTTPISQAQKLA-- 2996

Query: 2096 NPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQ 2155
                     G  Q Q  +Q   +P          +Q   P+ +  Q A   QQ   Q + 
Sbjct: 2997 ---------GAQQVQTQIQVAKLP--------QVVQQQTPVASIQQVASASQQASPQTVA 3039

Query: 2156 PPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQ 2215
                  + Q  QM +   T  +Q   +++++ + QQ     + P   PG  N  Q     
Sbjct: 3040 LTQATAAGQQVQM-IPAVTATAQ---VVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASS 3095

Query: 2216 GVGYPPQQQQRMQ 2228
                 P QQ ++Q
Sbjct: 3096 D---SPSQQPKLQ 3105



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 92/365 (25%), Positives = 130/365 (35%), Gaps = 45/365 (12%)

Query: 632  LLAEKIYKIQKELEEK--RRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLP 689
            L  E + K+QK+  +   +    Q Q+  P     V V  +  P    PQ   T   P P
Sbjct: 2775 LTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQL-TTVTAPRP 2833

Query: 690  DPSMIRGSVPNQMMPRIT--PQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNP 747
               +   +V N  + R+T  P S L   GQM    P              Q AQ     P
Sbjct: 2834 GALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAP--------------QPAQVALAKP 2879

Query: 748  PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPI 807
            P+   P     S     LP        MNV  I +A    Q    Q  ++    PV+   
Sbjct: 2880 PVVSVPAAVVSSPGVTTLP--------MNVAGISVAIGQPQKAAGQTVVAQ---PVHMQQ 2928

Query: 808  MPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPP 867
            +    Q + +   +  QP   Q  P+ V  +      T P  GAQQ  A      + T  
Sbjct: 2929 LLKLKQQA-VQQQKAIQPQAAQG-PAAVQQKITAQQITTP--GAQQKVAYAAQPALKTQF 2984

Query: 868  AMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAA-----PSADQPQQQPRSQQSTAA 922
               P  Q+Q L    +        +LPQ VQ   P A      SA Q Q  P++   T A
Sbjct: 2985 LTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQ-QASPQTVALTQA 3043

Query: 923  SVPTPTAPLLPPQPATPLSQPAVSIEGQV----SNPPSTSSTEVNSQAIAEK-QPSQEVK 977
            +       ++P   AT        I+ QV    S P  T      +Q  A    PSQ+ K
Sbjct: 3044 TAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPK 3103

Query: 978  MEAKM 982
            ++ ++
Sbjct: 3104 LQMRV 3108



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 68/288 (23%), Positives = 99/288 (34%), Gaps = 31/288 (10%)

Query: 821  QLPQPALHQNSPSPVPSRTPTPHHTP------PSIGAQQPPATTIPAPVPTPPAMPPGPQ 874
            ++P+  + + S S  P+  P            P    Q+P   T+  P   PP     P 
Sbjct: 1397 KIPRKLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTA-APT 1455

Query: 875  SQALHPPPRQTPTPPTTQLPQQVQPSLPAAP------SADQPQQQPRSQQSTAASVPTP- 927
            + +  P       PP        +    AAP      SA  P+ QP S  STAAS   P 
Sbjct: 1456 TASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPA 1515

Query: 928  ------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981
                  TA    P    P  Q      GQ + P       + SQA A     + VK+   
Sbjct: 1516 KLRAQTTAQASTPGQPPPQPQAPSHAAGQSALP---QRLVLPSQAQARLPSGEVVKIAQL 1572

Query: 982  MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAP 1041
              +  P+    QPE     + +  K   + ++ R       +     Q   S  Q   AP
Sbjct: 1573 ASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPL-----QLQGSVLQIVSAP 1627

Query: 1042 GQSKKKIFKPEELRQALM--PTLEALYRQDPESLPFRQPVDPQLLGIP 1087
            GQ   +   P  ++          AL  + P   P   P+ PQ +G+P
Sbjct: 1628 GQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQ-VGVP 1674



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 107/503 (21%), Positives = 152/503 (30%), Gaps = 156/503 (31%)

Query: 632  LLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDP 691
            L AE+I K +K L ++++ +       P  A   P    P P   QP P      PLP P
Sbjct: 2480 LRAERIAKEKKALADQQKAQQ------PAVAQPPPPQPQPPPPPQQPPP------PLPQP 2527

Query: 692  SMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQ---------- 741
                GS P    P + PQ    Q    +  QP   P +  P    G  A           
Sbjct: 2528 QAA-GSQPPAGPPAVQPQP---QPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSV 2583

Query: 742  ---------------------------------------PGALNPPMGYGPRM---QQPS 759
                                                   PGAL  P G  P      QP 
Sbjct: 2584 TGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPP 2643

Query: 760  NQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQ----AQMSSSSCPVNSP---IMPPGS 812
             +    P T  P        + +A + G   V+     A ++++  PV +P   ++P  S
Sbjct: 2644 PRAVGSPATATPDL------VSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVS 2697

Query: 813  QGSHIHCP--------------------------QLPQPALHQNSPSPVPSRTPTPHHTP 846
            Q + +  P                          Q  Q    Q       + T +    P
Sbjct: 2698 QATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP 2757

Query: 847  PSIGAQQPPATTIPAPVPTP-------------PAMPPGPQSQALHPPPRQTPTPPTTQL 893
               G  Q PA        TP             P  PP PQ+Q+  P P       T+Q 
Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQP 2817

Query: 894  PQQVQPSLPAAPSADQP-----------------------QQQPRSQQSTAASVPTPTAP 930
            PQQ  P L    +A +P                       Q Q + Q  T A  P   A 
Sbjct: 2818 PQQQSPQLTTV-TAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVAL 2876

Query: 931  LLPP---QPATPLSQPAVS--------IEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKME 979
              PP    PA  +S P V+        I   +  P   +   V +Q +   Q   ++K +
Sbjct: 2877 AKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPV-HMQQLLKLKQQ 2935

Query: 980  AKMEVDQPEPADTQPEDISESKV 1002
            A  +    +P   Q     + K+
Sbjct: 2936 AVQQQKAIQPQAAQGPAAVQQKI 2958



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 66/265 (24%), Positives = 88/265 (33%), Gaps = 56/265 (21%)

Query: 2141 QRAGLPQQQPQQQLQPP-MGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGP 2199
            Q  G     P QQL P   GGM P  Q                L  Q+  QQQ     GP
Sbjct: 495  QHPGADAGVPLQQLMPTAQGGMPPTPQAAQ-------------LAGQRQSQQQYDPSTGP 541

Query: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259
             +    + H    Q  G   PP         +      +  Q  Q PQ + A+    +  
Sbjct: 542  PVQNAASLHTPLPQLPG-RLPPAG-------VPTAALSSALQFAQQPQVVEAQTQLQIPV 593

Query: 2260 YQQRLLQQQMGSPVQPN------PMSPQQHML----PNQAQSPHLQGQQIPNSLSNQ--- 2306
              Q   Q  +  P  P+      P  P Q  L    P + Q    Q   +P  +++    
Sbjct: 594  KTQ---QPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLP 650

Query: 2307 VRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSP-------------QTSSPHPGLVA 2353
            V    P P P P S     +P     P PSP   SP               +S  PG+VA
Sbjct: 651  VDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVA 710

Query: 2354 AQANPMEQGHFASPDQNSMLSQLAS 2378
            +     +     SP QN+  SQ +S
Sbjct: 711  SAPTKPQ-----SPAQNATSSQDSS 730



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 51/223 (22%), Positives = 74/223 (33%), Gaps = 22/223 (9%)

Query: 809  PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPA----TTIPAPVP 864
            PP    + +H P LPQ  L    P   P+  PT   +     AQQP      T +  PV 
Sbjct: 541  PPVQNAASLHTP-LPQ--LPGRLP---PAGVPTAALSSALQFAQQPQVVEAQTQLQIPVK 594

Query: 865  TPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASV 924
            T     P P      PP  Q P PP+      +    P        Q     Q   +  +
Sbjct: 595  TQQPNVPIPA-----PPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRL 649

Query: 925  PTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP-------SQEVK 977
            P   AP  P    T  +     + G    P    S+ VN  + A  +        +  V 
Sbjct: 650  PVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVV 709

Query: 978  MEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK 1020
              A  +   P    T  +D S+  + +      +  +R  EL+
Sbjct: 710  ASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQVHQRIAELR 752



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 78/317 (24%), Positives = 107/317 (33%), Gaps = 33/317 (10%)

Query: 1920 GPPPAAVEMAMQIQRA---AETQRQMAHVQIFQRPIQHQMPPMTPMAPMG--------MN 1968
            G  P  V+  +Q  RA   +E + Q AH      P     P  +P AP          MN
Sbjct: 4    GTGPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMN 63

Query: 1969 PPPMTRGPSGHLEPGMGPT-GMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNM 2027
              P T          +GP  G  QQ   +   LP P     G    A     +HG P  +
Sbjct: 64   RSPATGQNVNITLQSVGPVVGGNQQITLAP--LPLPSPTSPGFQFSAQPRRFEHGSPSYI 121

Query: 2028 APQPGLGQV--GISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFI 2085
                 L Q     SP +P     QALQN+      P   L           +  +L   I
Sbjct: 122  QVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGF-VDASVLVRQI 180

Query: 2086 KQRAAKYANSNPQPIPGQPGMPQG-QPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAG 2144
                +   +   Q   G   + QG Q  LQ P  P          ++   P Q   Q  G
Sbjct: 181  SLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTP--------ITVRERRPSQPHTQSGG 232

Query: 2145 -LPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGP 2203
             +    PQ        G+ P A   ++    +P Q   I++ Q + QQQ  Q      GP
Sbjct: 233  TIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQ------GP 286

Query: 2204 GMANHNQFQQPQGVGYP 2220
             +     F++  GV  P
Sbjct: 287  PLPRPLGFERTPGVLLP 303



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 54/230 (23%), Positives = 74/230 (32%), Gaps = 13/230 (5%)

Query: 1805 FCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQG-LPSPTPATPTTPTGQQP 1863
            F  N + K      Q     A   R + AS   T         L + T A  +TP GQ P
Sbjct: 1474 FSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTP-GQPP 1532

Query: 1864 TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQT--AQPPLP-- 1919
              PQ P   +     P   + P   + QA  P  +     Q+   T PQ+  AQP  P  
Sbjct: 1533 PQPQAPSHAAGQSALPQRLVLP--SQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVT 1590

Query: 1920 -----GPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTR 1974
                      +     Q+      Q Q + +QI   P Q  +    P+    ++      
Sbjct: 1591 LQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVH 1650

Query: 1975 GPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQP 2024
            G  G   P  GP+     P     G      L  G P  A    +  G P
Sbjct: 1651 GALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVGEPGTASKPASPIGGP 1700



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 53/228 (23%), Positives = 77/228 (33%), Gaps = 18/228 (7%)

Query: 1812 KLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQP---TTPQT 1868
            KL+  +L   +Q  Q    R  +   T     +   P+   A P  P   +P   T    
Sbjct: 1420 KLKASRLFQPVQYGQKPEGRTVAFPSTHP--PRTAAPTTASAAPQGPLRGRPPIATFSAN 1477

Query: 1869 PQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG-PPPAAVE 1927
            P+  +   P   +      PR Q A   S   +           TAQ   PG PPP    
Sbjct: 1478 PEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQA 1537

Query: 1928 MAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPT 1987
             +    ++A  QR +   Q   R    ++  +  +A +         GP   +     P 
Sbjct: 1538 PSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASI--------TGPQSRVAQPETPV 1589

Query: 1988 GMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQ----HGQPLNMAPQP 2031
             +Q Q         Q +QL +G P     SV Q     GQP   AP P
Sbjct: 1590 TLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGP 1637



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 44/179 (24%)

Query: 810 PGSQGSHIHCPQLPQPALHQNSPSPV----PSRTPTPHHTPPSIGAQQ----PPATTIPA 861
           PGS+G         QPA     PSP     PS +P+   +P S   QQ     PAT    
Sbjct: 21  PGSEGEE-------QPAHPNPPPSPAAPFAPSASPSAPQSP-SYQIQQLMNRSPATGQNV 72

Query: 862 PVPTPPAMPP--GPQSQALHPPPRQTPTPP---------------------TTQLPQQVQ 898
            +      P   G Q   L P P  +PT P                     T+ L QQVQ
Sbjct: 73  NITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQ 132

Query: 899 PSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPST 957
              P  PS    Q    + Q+  A  P P   L    P       +V +  Q+S  PS+
Sbjct: 133 TQSPTQPSPGPGQ----ALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVR-QISLSPSS 186



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 55/233 (23%), Positives = 79/233 (33%), Gaps = 38/233 (16%)

Query: 102 QVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQP 161
           QV      Q SPG G     V+     AG   P +G+ +S P  G   ++ ++      P
Sbjct: 130 QVQTQSPTQPSPGPGQALQNVR-----AGAPGPGLGLCSSSPTGGFVDASVLVRQISLSP 184

Query: 162 AMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTE 221
           + G           G     +G G+   Q+  G+      +  +Q+P    G+   +   
Sbjct: 185 SSG-----------GHFVFQDGSGL--TQIAQGA------QVQLQHP----GTPITVRER 221

Query: 222 PLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSP---YTQNPGQQIGASGLGLQIQTKT 278
              Q   Q GG     GPQ           P  SP    T N   QI +   G  +Q + 
Sbjct: 222 RPSQPHTQSGGTIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQ 281

Query: 279 VLSNNLSPFAMDKKAVPG------GGMPNMGQQPAPQVQQPGLVTPVAQGMGS 325
           VL     P  +  +  PG      GG    G    P    P   T V  G+ S
Sbjct: 282 VLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSPPPPTSPSR-TAVPPGLSS 333



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 51/190 (26%), Positives = 66/190 (34%), Gaps = 30/190 (15%)

Query: 867  PAMPPGPQSQALHPPPR--QTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASV 924
            P    G   Q L P  +    PTP   QL  Q Q      PS   P Q        AAS+
Sbjct: 497  PGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQ-------NAASL 549

Query: 925  PTPTAPL---LPPQ--PATPLS-------QP-AVSIEGQVSNPPSTSSTEVNSQAIAEKQ 971
             TP   L   LPP   P   LS       QP  V  + Q+  P  T    V   A    Q
Sbjct: 550  HTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQ 609

Query: 972  PSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPS 1031
                    A++ +  P P   Q        V+  ++ S      ST L  +      +P 
Sbjct: 610  LPIPPSQPAQLALHVPTPGKVQ--------VQASQLSSLPQMVASTRLPVDPAPPCPRPL 661

Query: 1032 TSATQSSPAP 1041
             +++ SS AP
Sbjct: 662  PTSSTSSLAP 671



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 32/156 (20%), Positives = 63/156 (40%), Gaps = 13/156 (8%)

Query: 894  PQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSN 953
            PQ VQ  L  + +   P  +   Q +     P+P AP  P    +    P+  I+  ++ 
Sbjct: 7    PQNVQHQLQRSRAC--PGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNR 64

Query: 954  PPST-SSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTET 1012
             P+T  +  +  Q++       +    A +    P P+ T P     ++    +  S   
Sbjct: 65   SPATGQNVNITLQSVGPVVGGNQQITLAPL----PLPSPTSPGFQFSAQPRRFEHGSPSY 120

Query: 1013 EERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKI 1048
             + ++ L  +++ +      S TQ SP PGQ+ + +
Sbjct: 121  IQVTSPLSQQVQTQ------SPTQPSPGPGQALQNV 150



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 20/152 (13%)

Query: 828 HQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPT 887
           H   P  V  +       P S G +QP         P PP  P  P + +  P     P 
Sbjct: 3   HGTGPQNVQHQLQRSRACPGSEGEEQPAH-------PNPPPSPAAPFAPSASP---SAPQ 52

Query: 888 PPTTQLPQQVQPSLPAAPSADQPQQQ-----PRSQQSTAASVPTPTAPLLPPQPATPLS- 941
            P+ Q+ Q +  S     + +   Q        +QQ T A +P P+    P  P    S 
Sbjct: 53  SPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPS----PTSPGFQFSA 108

Query: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPS 973
           QP     G  S    TS      Q  +  QPS
Sbjct: 109 QPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPS 140


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 112/405 (27%), Positives = 142/405 (35%), Gaps = 42/405 (10%)

Query: 677  QPQPGMTSNGPLPD-PSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQH 735
            Q  P   +  PL + PS+    +     P  TP             Q P  P  TPP + 
Sbjct: 524  QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583

Query: 736  HGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQ 795
               +A P    PP    P +  P  QG  LP    P      T  P AP     P  QA 
Sbjct: 584  PSSIATP----PPQA-PPALASPPLQG--LPS---PPLSPLATPPPQAPPXLALPPLQAP 633

Query: 796  MSSSSCPVNSPIMPPGSQGSH---IHCPQLP----------QPALHQNSPSPVPSRTPTP 842
             S  + P  SP+  P  Q  +   +H  Q P           P     SP   PS TP P
Sbjct: 634  PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP-P 692

Query: 843  HHTPPSIGAQ------QPPATTIPAPVPTPPAMPPGPQS----QALHPPPRQTPTPPTTQ 892
               PPS+ A        PPA+   +P  TPP   P P +    Q    PP   P  P+  
Sbjct: 693  SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752

Query: 893  LPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA-PLLPPQPATPLSQPAVSIEGQV 951
             P +V P L AAP    P   P S   +  + P P A P L   P   L  P  S  GQ 
Sbjct: 753  PPPRVPPLL-AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811

Query: 952  SNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTE 1011
               PS S   +    +A   P     + A +    P P    P   +  +      +++ 
Sbjct: 812  PFSPSAS---LPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSV 867

Query: 1012 TEERSTELKTEIKEEEDQPSTSATQSSP-APGQSKKKIFKPEELR 1055
            +  R T             S S+T S P   G S      PEELR
Sbjct: 868  SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 136/569 (23%), Positives = 194/569 (34%), Gaps = 61/569 (10%)

Query: 1847 LPSPTPATPTTP-TGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA--- 1902
            L SP  + P+   T + P  P  P+P       PP   PP      A GP+S    A   
Sbjct: 249  LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 1903 ---GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
                +  P  PP  A  PLP   P +  +A  +  A  +      +Q          PP 
Sbjct: 309  PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL------PSPPA 362

Query: 1960 TP--MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMS 2017
            TP   AP  M  PPM   PS    P +        P  S    P P  L S     ++ S
Sbjct: 363  TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP--SLQAPPSPLALSSLQATTSLGS 420

Query: 2018 VAQHGQPLNMAPQPGLGQVGI-SPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHA 2076
                     +   P   Q  + SP +P +    +   L   L  P+SP  Q  +   +  
Sbjct: 421  PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS-PPLQAPLSLPASPPLQTSLSPAVSP 479

Query: 2077 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMP--QGQPGLQPPTMPGQQGVHSNPAMQNMN 2134
                L     Q  +  A+ +PQ       MP  + Q  L PP++       + P ++N+ 
Sbjct: 480  LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539

Query: 2135 PM-QAGVQRAGLPQQQPQQQ---------LQPPMGGMSPQAQQMNMNHNTMPSQFRDILR 2184
             +    +Q A  P   P  +         LQ P   ++    +   +  T P Q    L 
Sbjct: 540  SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599

Query: 2185 RQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQ 2244
               +     Q    P + P +A     Q P  +  PP Q          +          
Sbjct: 600  SPPL-----QGLPSPPLSP-LATPPP-QAPPXLALPPLQAPPSPPASPPLSP----LATP 648

Query: 2245 LPQALGAEAGASLQA--------YQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQG 2296
             PQA  A A   LQA          Q         PV P+   P Q   P    +P LQ 
Sbjct: 649  SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ--APPSLAAPPLQV 706

Query: 2297 QQIPNSLSNQVRSPQPVPS--PRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAA 2354
               P +      SP   PS  P PQ+ PP ++P  ++ P P        +++P P +   
Sbjct: 707  PPSPPA------SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760

Query: 2355 QANPMEQGHFASPDQNSMLSQLASNPGMA 2383
             A P  Q    SP  +  +S LA  P  A
Sbjct: 761  LAAPPLQVP-PSPPASLPMSPLAKPPPQA 788



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 146/603 (24%), Positives = 192/603 (31%), Gaps = 89/603 (14%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP 1907
            PSP  ATP       P+ P + Q    P  TPP+  PP +       P  Q   + Q  P
Sbjct: 333  PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT-----PPMQAPPSLQTIP 387

Query: 1908 P--TPPQTAQPPLPGPP-PAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAP 1964
            P   P     P L  PP P A+              Q  H  +   P Q Q    +P  P
Sbjct: 388  PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 1965 MGMNP--PPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGM---PRPAMMSVA 2019
                P  PP+             P  +   PP      P    L S +   P  A+ S+A
Sbjct: 448  ASTPPDSPPL-----------QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496

Query: 2020 QHGQ--PLNMAPQPGLG-QVGISP----LKPGTVSQQALQNLLRT----LRSPSSPLQQQ 2068
             H    PL+    P L  Q  ++P      P +++   L+NL       L++ S+PL   
Sbjct: 497  SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556

Query: 2069 QVLSI-------LHANPQLLAAFIKQRAAKYANSNPQ--------PIPGQPGMPQGQPGL 2113
             + +        L A P  L     +  +  A   PQ        P+ G P  P      
Sbjct: 557  HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT 616

Query: 2114 QPP------TMPGQQGVHSNPAMQNMNPMQAGVQRA--GLPQQQPQQQLQPP-----MGG 2160
             PP       +P  Q   S PA   ++P+     +A   L     Q    PP        
Sbjct: 617  PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676

Query: 2161 MSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYP 2220
             SP A        T PSQ    L    + Q      A P + P      Q   P  +  P
Sbjct: 677  FSPPASPPVSPSATPPSQAPPSLAAPPL-QVPPSPPASPPMSPSATPPPQAPPP--LAAP 733

Query: 2221 PQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP 2280
            P Q          M           P+     A   LQ          M    +P P +P
Sbjct: 734  PLQVPPSPPASPPMSPSATPP----PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789

Query: 2281 QQHMLPNQAQSPH----LQGQQIPNSLSNQVRSPQPVPSPR-------PQSQPPHSSP-S 2328
                 P     P       GQ   +  ++   SP   P P+       P  Q P S P S
Sbjct: 790  PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 2329 PRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGA 2388
            P +Q    P    P TS   P L  A A         SP      S   S P +A  H +
Sbjct: 850  PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP------SSTLSGPDLAG-HSS 902

Query: 2389 SAT 2391
            SAT
Sbjct: 903  SAT 905



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 135/576 (23%), Positives = 187/576 (32%), Gaps = 113/576 (19%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP-PYLPRTQAAGPVSQGKAAGQVT 1906
            PS T A P  P    P    TP P + P P+PP + P P  P + +A P  Q   +   T
Sbjct: 309  PSGTKARPVPP----PDNAATPLPATLP-PSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363

Query: 1907 PPT--PPQTAQPPLPGPP------------------------PAAVEMAMQIQRAAETQR 1940
            PP+  PP    PP+  PP                        P A+              
Sbjct: 364  PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 1941 QMAHVQIFQRPIQHQMPPMTPMAPMGMNP--PPMTRGPSGHLEPGMGPTGMQQQPPWSQG 1998
            Q  H  +   P Q Q    +P  P    P  PP+             P  +   PP    
Sbjct: 424  QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL-----------QAPLSLPASPPLQTS 472

Query: 1999 GLPQPQQLQSGM---PRPAMMSVAQHGQPLNMAPQPGLGQVGISPLK-PGTVSQQALQNL 2054
              P    L S +   P  A+ S+A H      +PQ  L  + + PL+   +++  +LQ  
Sbjct: 473  LSPAVSPLSSPLTIHPLQALSSLASH------SPQAPLSSLIMPPLETQSSLAPPSLQTP 526

Query: 2055 LRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQ 2114
              +L +P  PL+    L    A P L  A                       P   P L+
Sbjct: 527  PASLTTP--PLENLPSL----APPPLQTA---------------------SAPLTTPHLE 559

Query: 2115 PPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGM-SPQAQQMNMNHN 2173
             P  P    + + P+     P +     A  P Q P     PP+ G+ SP    +     
Sbjct: 560  TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL----A 615

Query: 2174 TMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQ 2233
            T P Q    L    +     Q    P   P ++       P     P        H +Q 
Sbjct: 616  TPPPQAPPXLALPPL-----QAPPSPPASPPLS-------PLATPSPQAPNALAVHLLQA 663

Query: 2234 MQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSP--QQHMLPNQAQS 2291
                      Q P +  A    S  A         + +P    P SP     M P+    
Sbjct: 664  PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723

Query: 2292 PHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP--PHSSPSPRMQP--QPSPHHVSPQTSSP 2347
            P     Q P  L+     P  VP   P S P  P ++P PR+ P     P  V P   + 
Sbjct: 724  P-----QAPPPLA---APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS 775

Query: 2348 HPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMA 2383
             P    A+  P      A+P   ++ S  AS PG A
Sbjct: 776  LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 87/331 (26%), Positives = 122/331 (36%), Gaps = 58/331 (17%)

Query: 660 NAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMS 719
           NAA  +P ++ P P +  P P +    P   PS+     P    P   P S         
Sbjct: 322 NAATPLPATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP----P 376

Query: 720 MAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQ-------PSNQGQFLPQTQFPS 772
           M  PP + +  PP+Q    L  P    PP        Q       P+ Q      T  P 
Sbjct: 377 MQAPPSL-QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435

Query: 773 QGMNVTNIPLAPSSG-------QAPVS-------QAQMSSSSCPVNSPI-MPPGSQGSHI 817
           Q       P  P+S        QAP+S       Q  +S +  P++SP+ + P    S +
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495

Query: 818 --HCPQLPQPAL------HQNSPSPVPSRTPTPHHTPPSI----GAQQPPATTIPAPVPT 865
             H PQ P  +L       Q+S +P   +TP    T P +        PP  T  AP+ T
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555

Query: 866 PPA-MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASV 924
           P    PP P    L  PP    TPP         P  P++ +   PQ  P        ++
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPP---------PETPSSIATPPPQAPP--------AL 598

Query: 925 PTPTAPLLPPQPATPLSQPAVSIEGQVSNPP 955
            +P    LP  P +PL+ P       ++ PP
Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 99/441 (22%), Positives = 150/441 (34%), Gaps = 35/441 (7%)

Query: 661  AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720
            A  + P+S +P   +  P P  T   P+P P      +P  + P     + L        
Sbjct: 293  APALGPLSSSP---LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349

Query: 721  AQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFP----SQGMN 776
            A P +    +PP       A P +  PP    P MQ P +  Q +P  Q P    S  + 
Sbjct: 350  APPSLQTLPSPP-------ATPPSQAPPSMTTPPMQAPPSL-QTIPPIQVPHSLTSPSLQ 401

Query: 777  VTNIPLAPSSGQAPVSQAQ---MSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPS 833
                PLA SS QA  S       ++ S    SP     S  S       P  +    +P 
Sbjct: 402  APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461

Query: 834  PVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAM--PPGPQSQALHPP--PRQTPTPP 889
             +P+  P      P++     P T  P    +  A   P  P S  + PP   + +  PP
Sbjct: 462  SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521

Query: 890  TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQ 942
            + Q P     SL   P  + P   P   Q+ +A + TP        AP     P +PL+ 
Sbjct: 522  SLQTPPA---SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 943  PAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKV 1002
            P       ++ PP  +   + S  + +  PS  +   A      P      P     S  
Sbjct: 579  PPPETPSSIATPPPQAPPALASPPL-QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637

Query: 1003 EDCKME--STETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMP 1060
                +   +T + +    L   + +    P  S    +P    +   +           P
Sbjct: 638  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697

Query: 1061 TLEALYRQDPESLPFRQPVDP 1081
            +L A   Q P S P   P+ P
Sbjct: 698  SLAAPPLQVPPSPPASPPMSP 718



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 81/291 (27%), Positives = 109/291 (37%), Gaps = 27/291 (9%)

Query: 1845 QGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904
            QGLPSP  +   TP  Q P  P    P  Q  P+PP S PP  P    +       A   
Sbjct: 604  QGLPSPPLSPLATPPPQAP--PXLALPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHL 660

Query: 1905 VTPP-TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963
            +  P +PP +     P  PPA+  ++      ++    +A   +   P     PPM+P A
Sbjct: 661  LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720

Query: 1964 -PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG 2022
             P    PPP+   P         P      PP S    P P+        P +++     
Sbjct: 721  TPPPQAPPPLAAPPL------QVPPSPPASPPMSPSATPPPRV-------PPLLA----A 763

Query: 2023 QPLNMAPQPGLGQVGISPL-KPGTVSQQALQN-LLRTLRSPSSPLQQQQVLSILHANPQL 2080
             PL + P P    + +SPL KP   +  AL    L+ L SP +    Q   S   + P  
Sbjct: 764  PPLQVPPSPP-ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822

Query: 2081 -LAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAM 2130
             LA    Q     A    Q  P  P  P  Q   +PPT PG     S P +
Sbjct: 823  PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTSVSGPRL 872



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 128/558 (22%), Positives = 185/558 (33%), Gaps = 51/558 (9%)

Query: 1833 ASMQRTGVVGQQQGLPSPTP-ATPTTPT----------GQQPTTPQTPQPTSQPQPTPPN 1881
            A  +R+   G + GLP P P A P  PT           +  TT  +P    +P      
Sbjct: 175  AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 1882 SMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQ 1941
              P     + +A P+S    +G     TP   A P  P P       A++  +    ++ 
Sbjct: 235  QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL---QALRPPQVTPPRKD 291

Query: 1942 MAHV--QIFQRPIQHQMPPMTPMAPM-----GMNPPPMTRGPSGHLEPGMGPTGMQQQPP 1994
             A     +   P+    P  T   P+        P P T  PS  L   +         P
Sbjct: 292  AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351

Query: 1995 WSQGGLPQPQQLQSGMPRPAMMSVAQHGQP-LNMAPQPGLGQVGISPLKPGTVSQQALQN 2053
             S   LP P         P+M +      P L   P   +     SP      S  AL +
Sbjct: 352  PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411

Query: 2054 LLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQ-----PGMPQ 2108
            L  T    S  LQ     S L  +P+   A +    ++ A++ P   P Q     P  P 
Sbjct: 412  LQATTSLGSPTLQATH--SFLTMSPRQTQASLTS-PSRPASTPPDSPPLQAPLSLPASPP 468

Query: 2109 GQPGLQPPTMP--GQQGVHSNPAMQNM--NPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQ 2164
             Q  L P   P      +H   A+ ++  +  QA +    +P  + Q  L PP    +P 
Sbjct: 469  LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP-SLQTPP 527

Query: 2165 AQQMNMNHNTMPSQFRDILRRQQ--MMQQQQQQGAGPGIGPGMANHNQF-----QQPQGV 2217
            A         +PS     L+     +     +    P   P  A  +       + P  +
Sbjct: 528  ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587

Query: 2218 GYPPQQ--QQRMQHHMQQMQQGNMGQIG-QLPQALGAEAGASLQAYQQRLLQQQMGSPVQ 2274
              PP Q         +Q +    +  +    PQA    A   LQA         +     
Sbjct: 588  ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647

Query: 2275 PNPMSPQQ---HMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRM 2331
            P+P +P     H+L      P     Q P S      SP   PS  P SQ P S  +P +
Sbjct: 648  PSPQAPNALAVHLLQAPFSPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPL 704

Query: 2332 QPQPSPHHVSPQTSSPHP 2349
            Q  PSP    P + S  P
Sbjct: 705  QVPPSPPASPPMSPSATP 722



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 76/295 (25%), Positives = 105/295 (35%), Gaps = 32/295 (10%)

Query: 1855 PTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYL---PRTQAAGPVSQGKAAGQVTPP--T 1909
            P +P  Q P +P    P S P  TPP+  PP L   P      P +    +   TPP   
Sbjct: 668  PPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 1910 PPQTAQPPL--PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPM----- 1962
            PP  A PPL  P  PPA+  M+            +A   +   P      PM+P+     
Sbjct: 727  PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786

Query: 1963 -APMGMNPPPMTRGPSGHLE-PGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQ 2020
             AP  +  PP+   PS     PG  P       P S    P PQ        P +++   
Sbjct: 787  QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-------APPVLAAPL 839

Query: 2021 HGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQL 2080
               P +    P L Q    P  PG  +  +   L   L +P  P    +  S   + P L
Sbjct: 840  LQVPPSPPASPTL-QAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDL 897

Query: 2081 LAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNP 2135
                     +  A S P+ + G    P+G     PP  P  +    +PA  +  P
Sbjct: 898  AG------HSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRGP 944



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 79/315 (25%), Positives = 113/315 (35%), Gaps = 63/315 (20%)

Query: 672 GPNMGQPQPGMTSNG---------PLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQ 722
           GP  G P P M             P P PS           P   P+  ++   + S  +
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSA------RPRPPTEGPRKSVSSASEHSTTE 219

Query: 723 PPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQ----FPSQ----G 774
           P    R+ P     G L +P + +      P +  P+  G     T      PSQ    G
Sbjct: 220 PSPAARRRPSAG--GGLQRPASRSLSSSATP-LSSPARSGPSARGTPRAPAHPSQPKPKG 276

Query: 775 MNVTNIP-LAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPS 833
           +     P + P    A  +   +SSS      P+  P   G+      +P P    N+ +
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSS------PLATPSPSGTKAR--PVPPP---DNAAT 325

Query: 834 PVPSRTPT--PHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTP----T 887
           P+P+  P   P  TP  +    P A      +P+PPA PP     ++  PP Q P    T
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385

Query: 888 PPTTQLPQQV-QPSLPAAP------------SADQPQQQ------PRSQQSTAASVPTPT 928
            P  Q+P  +  PSL A P            S   P  Q        S + T AS+ +P+
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445

Query: 929 APLLPPQPATPLSQP 943
            P   P  + PL  P
Sbjct: 446 RPASTPPDSPPLQAP 460



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 103/392 (26%), Positives = 122/392 (31%), Gaps = 128/392 (32%)

Query: 671 PGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT--PQSGLNQFGQMSMAQPPIVPR 728
           P P   Q  P   +  P   PS I  + P Q  P +   P  GL          PP+ P 
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSI-ATPPPQAPPALASPPLQGL--------PSPPLSPL 614

Query: 729 QTPPLQHHGQLAQPGALNPPMGYG---------PRMQQPSNQGQFLPQTQFPSQGMNVTN 779
            TPP Q    LA P    PP             P  Q P+     L Q  F         
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 780 IPLAP------SSGQAPVSQAQMSSSSCPVNSPIMPPGS---QGSHIHCPQLPQPALH-- 828
            P +P      S    P SQA  S ++ P+  P  PP S     S    PQ P P     
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734

Query: 829 -QNSPSPV------PSRTPTPHHTPPSIGAQ------QPPATTIPAPVPTPPAMPPG--- 872
            Q  PSP       PS TP P   PP + A        PPA+   +P+  PP   P    
Sbjct: 735 LQVPPSPPASPPMSPSATPPPR-VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 873 -PQSQALHPPPR----QTPTPPTTQLPQ-------------------QVQPSLPAAPSAD 908
            P  QAL  PP     Q P  P+  LP                    QV PS PA+P+  
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853

Query: 909 QPQQQP--------------------------RSQQST---------------------- 920
            P++ P                          RS  ST                      
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913

Query: 921 --------AASVPTPTAPLLPPQPATPLSQPA 944
                   AA+ P P A L    PA     PA
Sbjct: 914 YDSGPEGGAAASPPPDAELAACHPAAWSRGPA 945



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 116/510 (22%), Positives = 172/510 (33%), Gaps = 99/510 (19%)

Query: 666  PVSMNPGPNMGQPQPGM--TSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-- 721
            P S  P    G+  P    TS GP+  P    G+      P    Q GL    + ++A  
Sbjct: 90   PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT----RPGPLGQKGLRISAEETVARG 145

Query: 722  ---QPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPR-------MQQPSNQGQFLPQTQFP 771
               + P     +   +       PG  +P M    R       + +P+   +  P T+ P
Sbjct: 146  KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 772  SQGMNVTN-------IPLA---PSSG---QAPVSQAQMSSSSCPVNSPIMP-PGSQGSHI 817
             + ++  +        P A   PS+G   Q P S++ +SSS+ P++SP    P ++G+  
Sbjct: 206  RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS-LSSSATPLSSPARSGPSARGT-- 262

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQA 877
                 P+   H + P P              + A +PP  T       PP     P    
Sbjct: 263  -----PRAPAHPSQPKP------------KGLQALRPPQVT-------PPRKDAAPALGP 298

Query: 878  LHPPPRQTPTPPTTQL-----PQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLL 932
            L   P  TP+P  T+      P      LPA      P   P      + S P P+   L
Sbjct: 299  LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQTL 357

Query: 933  PPQPATPLSQPAVSIEGQVSNPPSTSST--------EVNSQAI-AEKQPSQEVKMEAKME 983
            P  PATP SQ   S+       P +  T         + S ++ A   P     ++A   
Sbjct: 358  PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 984  VDQP-----------EPADTQPEDISESKVEDCKMESTETE-----ERSTELKTEIKEEE 1027
            +  P            P  TQ    S S+      +S   +       S  L+T +    
Sbjct: 418  LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477

Query: 1028 DQPSTSATQSSPAPGQSKKKIFKPE-ELRQALMPTLEALYRQDPESL--PFRQPVDPQLL 1084
              P +S     P    S      P+  L   +MP LE      P SL  P      P L 
Sbjct: 478  -SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536

Query: 1085 GIPDYFDIVKSPMDLSTIKRKLDTGQYQEP 1114
             +P       +P  L T    L T   + P
Sbjct: 537  NLPSL-----APPPLQTASAPLTTPHLETP 561



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 64/233 (27%), Positives = 91/233 (39%), Gaps = 21/233 (9%)

Query: 659 PNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQM 718
           P+     P+S +  P    P P   +  PL  P     S P  M P  TP   +      
Sbjct: 708 PSPPASPPMSPSATPPPQAPPP--LAAPPLQVPPSPPASPP--MSPSATPPPRVPPL--- 760

Query: 719 SMAQPPI-VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQ-PSNQGQFLPQTQF-PSQGM 775
            +A PP+ VP   P       LA+P    PP    P +Q  PS    F  Q  F PS  +
Sbjct: 761 -LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819

Query: 776 NVTNI----PLAPSSGQAPVSQAQMSSSSCP-VNSPIMPPG-SQGSHIHCPQLPQPALHQ 829
            ++ +    P AP    AP+ Q   S  + P + +P  PP     + +  P+L       
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP- 878

Query: 830 NSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPP 882
             P P PSR+P+   + P +      AT+ P  +    + P G    A  PPP
Sbjct: 879 -GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG--GAAASPPP 928



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 72/305 (23%), Positives = 102/305 (33%), Gaps = 38/305 (12%)

Query: 658  LPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQ 717
            +P      P+ + P P    P   +    P   P++   + P Q +P   P S   Q   
Sbjct: 757  VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL--ATPPLQALPS-PPASFPGQAPF 813

Query: 718  MSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMG-YGPRMQQPSNQGQFLPQTQFPSQGMN 776
               A  P+ P  TPP Q    LA P    PP     P +Q P       P T  P   ++
Sbjct: 814  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-----PPTPGPDTSVS 868

Query: 777  VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPAL-HQNSPSPV 835
               + LA + G  P      SS+       +  P   G        P+    + + P   
Sbjct: 869  GPRLTLALAPGPPPPPSRSPSST-------LSGPDLAGHSSSATSTPEELRGYDSGPEGG 921

Query: 836  PSRTPTP-------HHTPPSIGAQQPPAT--TIPAPVPTPPAMPPGPQSQALHPPPRQTP 886
             + +P P       H    S G   P A      AP+P PPA  PG              
Sbjct: 922  AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC-------- 973

Query: 887  TPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVS 946
            T   T+ P+   P    AP A  P   P +    AA+     A    P+ A     P  +
Sbjct: 974  TIYETEGPESATP----APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029

Query: 947  IEGQV 951
            ++  V
Sbjct: 1030 LQASV 1034



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 73/329 (22%), Positives = 110/329 (33%), Gaps = 63/329 (19%)

Query: 2087 QRAAKYANSNPQPI--PGQ------PGMPQGQPGLQ------------------PPTMPG 2120
            +RA    N++P P+  PG+      PG P GQ GL+                       G
Sbjct: 101  ERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSAG 159

Query: 2121 QQGVHSNPAMQNMNPMQAGVQRA-----GLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTM 2175
             +   S P     +P  A   RA     GLP+  P  + +PP  G        + +  T 
Sbjct: 160  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 2176 PSQFRDILRR--------QQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRM 2227
            PS      RR        Q+   +     A P   P  +  +    P+   +P Q + + 
Sbjct: 220  PS---PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276

Query: 2228 QHHMQQMQ--------QGNMGQIGQLPQALGAEAGASLQAY------QQRLLQQQMGSP- 2272
               ++  Q           +G +   P A  + +G   +           L      SP 
Sbjct: 277  LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336

Query: 2273 -VQPNPMSPQQHMLPNQAQS----PHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSP 2327
               P P++P     P   Q+    P     Q P S++       P     P  Q PHS  
Sbjct: 337  LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396

Query: 2328 SPRMQPQPSPHHVSPQTSSPHPGLVAAQA 2356
            SP +Q  PSP  +S   ++   G    QA
Sbjct: 397  SPSLQAPPSPLALSSLQATTSLGSPTLQA 425



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 44/220 (20%)

Query: 1845 QGLPSPTPA----TPTTPTGQQPTTP-QTPQPTSQP---------QPTPPNSMPPYLPR- 1889
            Q LPSP  +     P +P+   P +P  TP P + P          P+PP S     PR 
Sbjct: 798  QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 857

Query: 1890 -------TQAAGP-VSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQ 1941
                   T  +GP ++   A G   PP P ++    L GP     ++A     A  T  +
Sbjct: 858  PPTPGPDTSVSGPRLTLALAPG--PPPPPSRSPSSTLSGP-----DLAGHSSSATSTPEE 910

Query: 1942 MAHVQIFQRPIQHQMPPMTPMAPM-GMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
            +              PP  P A +   +P   +RGP+    P +   G    P      L
Sbjct: 911  LRGYDSGPEGGAAASPP--PDAELAACHPAAWSRGPA----PPLAFRGAPGAP------L 958

Query: 2001 PQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040
            P P     G     + ++ +   P +  P PG    G SP
Sbjct: 959  PWPPATGPG-SADGLCTIYETEGPESATPAPGALDPGPSP 997


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 104/357 (29%), Positives = 121/357 (33%), Gaps = 60/357 (16%)

Query: 1842 GQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPP---NSMPPYLPRTQAAGPVSQ 1898
            G Q   P P P  P  P  Q    PQ P P  +PQ  PP    S  P  P  +  GP  Q
Sbjct: 65   GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ 124

Query: 1899 GKAAGQVTPPTPPQTAQPPLP-------GPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951
            G    Q  PP PP   Q P P       GPPP         Q   +++   +     Q P
Sbjct: 125  GGNQPQ-GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183

Query: 1952 -----IQHQMPPMTPMAPMGMNP--------PPMTRGPSGHLEPGMGPTGMQQQPPWS-Q 1997
                  Q Q PP  P  P G  P        PP    P G    G   +   + PP   Q
Sbjct: 184  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243

Query: 1998 GGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRT 2057
            G  PQ      G P P        G+P    PQ G    G  P  PG       Q   ++
Sbjct: 244  GPPPQGGNQPQGPPPPP-------GKPQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKS 294

Query: 2058 LRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQP--GLQP 2115
              S S P + Q         PQ               + PQ  P  PG PQG P  G   
Sbjct: 295  RSSRSPPGKPQ------GPPPQ-------------GGNQPQGPPPPPGKPQGPPPQGGNK 335

Query: 2116 PTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQ-----QLQPPMGGMSPQAQQ 2167
            P  P   G    P  Q  +  ++     G PQ  PQQ     Q  PP  G +PQ  Q
Sbjct: 336  PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 392



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 119/425 (28%), Positives = 133/425 (31%), Gaps = 112/425 (26%)

Query: 1845 QGLPSPT--PATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-----PPYLPRTQAAGPVS 1897
            QG PSP   P  P    G QP  P  P P  +PQ  PP        PP  P  +  GP  
Sbjct: 48   QGPPSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPP 103

Query: 1898 QG-KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQM 1956
            QG K+    +PP  PQ       GPPP                         Q   Q Q 
Sbjct: 104  QGDKSRSPRSPPGKPQ-------GPPP-------------------------QGGNQPQG 131

Query: 1957 PPMTPMAPMGMNP--------PPMTRGPSGHLEPGMGPTGMQQQPPWS-QGGLPQPQQLQ 2007
            PP  P  P G  P        PP    P G    G   +   + PP   QG  PQ     
Sbjct: 132  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191

Query: 2008 SGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPL-KPGTVSQQALQNLLRTLRSPSSPLQ 2066
             G P P        G+P    PQ G    G  P  KP     Q   N  ++ RSP    Q
Sbjct: 192  QGPPPPP-------GKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-DNKSQSARSPPGKPQ 243

Query: 2067 QQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQP--------GLQPPTM 2118
                       PQ               + PQ  P  PG PQG P        G  PP  
Sbjct: 244  GPP--------PQ-------------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 282

Query: 2119 P---------GQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN 2169
            P           +   S P      P Q G Q  G P    + Q  PP GG  PQ     
Sbjct: 283  PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342

Query: 2170 MNHNTMPSQFRDILRRQQM-----MQQQQQQGAGPGIGPGMANHNQFQ-------QPQGV 2217
                  P Q     R  +          QQ+G  P   P  A  N  Q       QPQG 
Sbjct: 343  GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402

Query: 2218 GYPPQ 2222
              PPQ
Sbjct: 403  PRPPQ 407



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 136/530 (25%), Positives = 162/530 (30%), Gaps = 135/530 (25%)

Query: 1822 LQQAQMLRRRMASMQRTGVV-GQQQGLPSP---TPATPTTPTGQQPTTPQTPQPTSQPQP 1877
            L  AQ L   ++  +   ++ G  QG P      P  P +P G+    P  PQ  +QPQ 
Sbjct: 13   LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPP--PQGGNQPQG 70

Query: 1878 TPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAE 1937
             PP   PP  P+    GP  QG       P  PP   +P   GPPP   +         +
Sbjct: 71   PPP---PPGKPQ----GPPPQGGNK----PQGPPPPGKPQ--GPPPQGDKSRSPRSPPGK 117

Query: 1938 TQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQ 1997
             Q         Q   Q Q PP  P  P G  PPP      G+   G  P G  Q PP   
Sbjct: 118  PQGPPP-----QGGNQPQGPPPPPGKPQG--PPPQ----GGNKPQGPPPPGKPQGPP--- 163

Query: 1998 GGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRT 2057
               PQ          P        G+P    PQ G    G  P  PG             
Sbjct: 164  ---PQGDNKSRSSRSPP-------GKPQGPPPQGGNQPQGPPP-PPG------------- 199

Query: 2058 LRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPT 2117
               P  P  Q                           + PQ  P  PG PQG P   P  
Sbjct: 200  --KPQGPPPQ-------------------------GGNKPQG-PPPPGKPQGPP---PQG 228

Query: 2118 MPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPS 2177
                Q   S P      P Q G Q  G P    + Q  PP GG  PQ           P 
Sbjct: 229  DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 288

Query: 2178 QFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQG 2237
            Q     R  +    + Q       GP     NQ   PQG   PP + Q           G
Sbjct: 289  QGGSKSRSSRSPPGKPQ-------GPPPQGGNQ---PQGPPPPPGKPQ-----------G 327

Query: 2238 NMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQ 2297
               Q G  PQ                        P +P    PQ       A+SP  + Q
Sbjct: 328  PPPQGGNKPQG--------------------PPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367

Query: 2298 QIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSP 2347
              P    N  + P P     PQ   P + P+ + Q  P P    PQ   P
Sbjct: 368  GPPQQEGNNPQGPPPPAGGNPQQ--PQAPPAGQPQGPPRP----PQGGRP 411



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 91/309 (29%), Positives = 106/309 (34%), Gaps = 44/309 (14%)

Query: 671 PGPNMGQP-QPGMTSNGPLPDPSMIRGSVPN----------QMMPRITPQSGLNQFGQMS 719
           PG   G P Q G    GP P P   +G  P              P+  P  G N+    S
Sbjct: 115 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK--SRS 172

Query: 720 MAQPPIVPRQTPPL---QHHGQLAQPGA-LNPPMGYGPRMQQPSNQGQFLPQTQFPSQGM 775
              PP  P+  PP    Q  G    PG    PP   G + Q P   G+  PQ   P QG 
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGP-PPQGD 229

Query: 776 NVTNIPLAPSS---GQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSP 832
           N +    +P     G  P    Q      P   P  PP   G+    PQ P P      P
Sbjct: 230 NKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK---PQGPPPPGKPQGP 286

Query: 833 SPVPSRTPTPHHTPPSIGAQQPP-ATTIPAPVPTPPAMPPGPQSQALH-----PPPRQTP 886
            P          +PP      PP     P   P PP  P GP  Q  +     PPP +  
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346

Query: 887 TPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVS 946
            PP    PQ    S  A     +PQ  P+ Q+      P P A   P QP  P   PA  
Sbjct: 347 GPP----PQGGSKSRSARSPPGKPQGPPQ-QEGNNPQGPPPPAGGNPQQPQAP---PA-- 396

Query: 947 IEGQVSNPP 955
             GQ   PP
Sbjct: 397 --GQPQGPP 403



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 81/300 (27%), Positives = 92/300 (30%), Gaps = 28/300 (9%)

Query: 659 PNAAGMVPVSMNPGPNMGQ---PQPGMTSNGPLPDPSMIRGSVP-------NQMMPRITP 708
           P   G  P    P P   Q   PQ G    GP P P   +G  P       +   P   P
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGKPQGPPPQGDNKSRSSRSPPGKP 180

Query: 709 QSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQ----PGALNPPMGYGPRMQQPSNQGQF 764
           Q    Q G      PP   +   P    G   Q    PG    P   G    Q +     
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG 240

Query: 765 LPQTQFPSQGMNVTNIPLAPSSGQAPVSQA-QMSSSSCPVNSPIMPPGSQGSHIHCPQLP 823
            PQ   P  G      P  P   Q P  Q         P   P  PP   GS     + P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 824 QPALHQNSPSPVPSRTPTPHHTPPSIGAQQ--PPATTIPAPVPTPPAMPPGP------QS 875
            P   Q  P   P     P   PP  G  Q  PP        P PP  P GP      +S
Sbjct: 301 -PGKPQGPP---PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 876 QALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQ 935
           ++   PP +   PP  +      P  PA  +  QPQ  P  Q       P    P  PPQ
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 90/346 (26%), Positives = 110/346 (31%), Gaps = 31/346 (8%)

Query: 671 PGPNMGQP-QPGMTSNGPLPDPSMIRGSVP-NQMMPRITPQSGLNQ------FGQMSMAQ 722
           PG   G P Q G    GP P P   +G  P     P+  P  G  Q          S   
Sbjct: 54  PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113

Query: 723 PPIVPRQTPPL---QHHGQLAQPG-ALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVT 778
           PP  P+  PP    Q  G    PG    PP   G + Q P   G+  PQ   P QG N +
Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGP-PPQGDNKS 170

Query: 779 NIPLAP---SSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPV 835
               +P     G  P    Q      P   P  PP   G+    PQ P P      P P 
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK---PQGPPPPGKPQGPPPQ 227

Query: 836 PSRTPTPHHTPPSIGAQQPP-ATTIPAPVPTPPAMPPGPQSQALH-----PPPRQTPTPP 889
                    +PP      PP     P   P PP  P GP  Q  +     PPP +   PP
Sbjct: 228 GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 287

Query: 890 TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEG 949
               PQ    S  +     +PQ  P    +     P P      P P            G
Sbjct: 288 ----PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343

Query: 950 QVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPE 995
           +   PP    ++  S      +P    + E       P PA   P+
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 389



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 119/478 (24%), Positives = 140/478 (29%), Gaps = 144/478 (30%)

Query: 1891 QAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR 1950
            Q A P    K  G  +PP  PQ       GPPP                         Q 
Sbjct: 37   QGAPPQGGNKPQGPPSPPGKPQ-------GPPP-------------------------QG 64

Query: 1951 PIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGM 2010
              Q Q PP  P  P G  PPP      G+   G  P G  Q PP        PQ  +S  
Sbjct: 65   GNQPQGPPPPPGKPQG--PPPQ----GGNKPQGPPPPGKPQGPP--------PQGDKSRS 110

Query: 2011 PRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV 2070
            PR      +  G+P    PQ G    G  P  PG                P  P  Q   
Sbjct: 111  PR------SPPGKPQGPPPQGGNQPQGPPP-PPG---------------KPQGPPPQ--- 145

Query: 2071 LSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAM 2130
                                    + PQ  P  PG PQG P   P      +   S P  
Sbjct: 146  ----------------------GGNKPQG-PPPPGKPQGPP---PQGDNKSRSSRSPPGK 179

Query: 2131 QNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQ 2190
                P Q G Q  G P    + Q  PP GG  PQ           P Q  +         
Sbjct: 180  PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN-------KS 232

Query: 2191 QQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALG 2250
            Q  +   G   GP     NQ   PQG   PP + Q           G   Q G  PQ   
Sbjct: 233  QSARSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQ-----------GPPPQGGNKPQGPP 278

Query: 2251 AEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP 2310
                            +  G P Q    S      P + Q P  QG        NQ + P
Sbjct: 279  PPG-------------KPQGPPPQGGSKSRSSRSPPGKPQGPPPQG-------GNQPQGP 318

Query: 2311 QPVPSPRPQSQPPHSS-----PSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGH 2363
             P P  +PQ  PP        P P  +PQ  P     ++ S        Q  P ++G+
Sbjct: 319  PPPPG-KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 80/309 (25%), Positives = 99/309 (32%), Gaps = 43/309 (13%)

Query: 2055 LRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQP--- 2111
            L + ++ +  + Q++  S++  NPQ         A     + PQ  P  PG PQG P   
Sbjct: 13   LSSAQNLNEDVSQEESPSLIAGNPQ--------GAPPQGGNKPQGPPSPPGKPQGPPPQG 64

Query: 2112 GLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQ------QLQPPMGGMSPQA 2165
            G QP   P   G    P  Q  N  Q G    G PQ  P Q         PP     P  
Sbjct: 65   GNQPQGPPPPPGKPQGPPPQGGNKPQ-GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123

Query: 2166 QQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQ 2225
            Q  N      P   +         Q    QG     GP      Q   PQG       + 
Sbjct: 124  QGGNQPQGPPPPPGKP--------QGPPPQGGNKPQGPPPPGKPQGPPPQG-----DNKS 170

Query: 2226 RMQHHMQQMQQGNMGQIGQLPQAL----GAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQ 2281
            R         QG   Q G  PQ      G   G   Q   +    Q    P +P    PQ
Sbjct: 171  RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK---PQGPPPPGKPQGPPPQ 227

Query: 2282 QHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVS 2341
                   A+SP  + Q  P    NQ + P P     P  +P    P    +PQ  P    
Sbjct: 228  GDNKSQSARSPPGKPQGPPPQGGNQPQGPPP-----PPGKPQGPPPQGGNKPQGPPPPGK 282

Query: 2342 PQTSSPHPG 2350
            PQ   P  G
Sbjct: 283  PQGPPPQGG 291



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 56/214 (26%), Positives = 64/214 (29%), Gaps = 27/214 (12%)

Query: 766 PQTQFPSQGMNVTNIPLAPSSGQAPVSQA--QMSSSSCPVNSPIMPPGSQGSHIHCPQLP 823
           PQ   P  G      P  P   Q P  Q   Q      P   P  PP   G+    PQ P
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK---PQGP 92

Query: 824 QPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALH---- 879
            P      P P   ++ +P   P       P     P   P PP  P GP  Q  +    
Sbjct: 93  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152

Query: 880 PPP------------------RQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTA 921
           PPP                  R  P  P    PQ         P   +PQ  P    +  
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212

Query: 922 ASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPP 955
              P P  P  PP      SQ A S  G+   PP
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 81/289 (28%), Positives = 92/289 (31%), Gaps = 89/289 (30%)

Query: 2096 NPQPIPGQPG-MPQGQPGLQPPTMPGQ-QGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQ 2153
            NPQ  P Q G  PQG     PP+ PG+ QG           P Q G Q  G P    + Q
Sbjct: 35   NPQGAPPQGGNKPQG-----PPSPPGKPQGP----------PPQGGNQPQGPPPPPGKPQ 79

Query: 2154 LQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQ 2213
              PP GG  PQ                               G  P   PG        +
Sbjct: 80   GPPPQGGNKPQ-------------------------------GPPP---PG--------K 97

Query: 2214 PQGVGYPPQ-QQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSP 2272
            PQG   PPQ  + R         QG   Q G  PQ      G            +  G P
Sbjct: 98   PQGP--PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG------------KPQGPP 143

Query: 2273 VQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQ 2332
             Q     PQ    P + Q P  QG        N+ RS +  P  +PQ  PP        Q
Sbjct: 144  PQGGN-KPQGPPPPGKPQGPPPQGD-------NKSRSSRSPPG-KPQGPPPQGGN----Q 190

Query: 2333 PQ-PSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNP 2380
            PQ P P    PQ   P  G    Q  P        P Q    SQ A +P
Sbjct: 191  PQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGDNKSQSARSP 238



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 30/104 (28%), Positives = 34/104 (32%), Gaps = 22/104 (21%)

Query: 1842 GQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNS--------MPPYLPR---- 1889
            G Q   P P P  P  P  Q    PQ P P  +PQ  PP           PP  P+    
Sbjct: 312  GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371

Query: 1890 ----------TQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPP 1923
                        A G   Q +A     P  PP+  Q   P  PP
Sbjct: 372  QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 34/135 (25%), Positives = 46/135 (34%), Gaps = 26/135 (19%)

Query: 2255 ASLQAYQQRLLQQQMGSPVQPNPMS--PQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP 2312
            +S Q   + + Q++  S +  NP    PQ    P    SP  + Q  P    NQ + P P
Sbjct: 14   SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73

Query: 2313 VPSP----------RPQSQPPHSSP--------------SPRMQPQPSPHHVSPQTSSPH 2348
             P            +PQ  PP   P              SP  +PQ  P     Q   P 
Sbjct: 74   PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 133

Query: 2349 PGLVAAQANPMEQGH 2363
            P     Q  P + G+
Sbjct: 134  PPPGKPQGPPPQGGN 148


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 122/513 (23%), Positives = 186/513 (36%), Gaps = 78/513 (15%)

Query: 641  QKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPN 700
            ++E  E+ R +  +  +LP    +VP +  P P   Q QP  +    L  P  ++  +P 
Sbjct: 292  RRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRS----LFQPQPLQPLLPV 347

Query: 701  QMMPRITPQSGLN-----QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRM 755
            Q     +P  G++     +  +M M  PP+ P+Q  P   H      G +  P+   P +
Sbjct: 348  QHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQ--PKNIHINPHFKGTVVTPVQV-PLL 404

Query: 756  QQPSNQGQFLPQTQFPS--QGMNVTNIPLAPSSGQAP--VSQAQMSSSSCPVNSPIMPPG 811
              PS     +   +FP   +    T  P+  S  Q P    Q Q  +   P +      G
Sbjct: 405  PVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLG 464

Query: 812  SQG-----SHIHC-----PQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPA 861
              G     SH+       P  P P    NS  PVP+++P P   P     QQ      P 
Sbjct: 465  VSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPR 524

Query: 862  PVPTPPAM-PPG---------PQSQALHP--PPRQ--TPTPPTTQLPQQVQPSL------ 901
              P  PA+ PPG         P S    P  PPRQ   P P    LP   QP+L      
Sbjct: 525  ERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHP 584

Query: 902  ----PAAPSADQPQQQPRSQ---------QSTAASVPTPTAP----------------LL 932
                P  P   QPQQQP  Q         Q      P P  P                 +
Sbjct: 585  PLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSV 644

Query: 933  PPQPATPLSQPAVSIEGQVSNPPSTSSTE--VNSQAIAEKQPSQEVKMEAKMEVDQPEPA 990
            PP P  P+SQP      Q + P ++SS       Q +     SQ V      ++    P 
Sbjct: 645  PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPR 704

Query: 991  DTQPEDISESKVEDCKMESTE-TEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIF 1049
            ++   ++  +     +M S+  +   S ++K  +       + + ++SS    + K K  
Sbjct: 705  NSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPA 764

Query: 1050 KPEELRQALMPTLEALYRQDPESLPFRQPVDPQ 1082
             P    +    T      +D E+  +R  ++ Q
Sbjct: 765  SPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQ 797



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 115/434 (26%), Positives = 166/434 (38%), Gaps = 100/434 (23%)

Query: 687  PLPDPSMIRGS--VPNQM-MPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPG 743
            P P P+++  S  VP Q  +P   P    NQ GQ      P+ PR+ P         +P 
Sbjct: 485  PPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQ-----PVFPRERP--------VRP- 530

Query: 744  ALNPPMGYGP-RMQQPSNQGQ--FLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSS 800
            AL PP   G     QP +     F+P  Q           P  P  GQ  +      +  
Sbjct: 531  ALQPPGPVGILHFSQPGSATTRPFIPPRQ-----------PFLPGPGQPFLPTHTQPNLQ 579

Query: 801  CPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIP 860
             P++ P+ PP       H PQ  QP            + P P H PP     QPP    P
Sbjct: 580  GPLHPPLPPP-------HQPQPQQP-----------QQQPPPQHQPPHQPPHQPPPQHQP 621

Query: 861  APVPTPPAMPPGPQSQALH------PPPRQTPTPPTTQLPQQVQPSLPAAPSADQ--PQQ 912
             P   PP  PP  Q    H      PPP    + P  Q    VQ + P A S+    PQ+
Sbjct: 622  PP-QHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQP--QFRPHVQTAQPQASSSRMQCPQR 678

Query: 913  QPRSQQSTAASVPTPTAPLLPPQPATPLSQ--------PAVSIEGQVSNPPSTSSTEVN- 963
            Q     +T+ +V     P+   QP  P +         P+  IE   S   +T S +V  
Sbjct: 679  QGLRHNTTSQNVSK--RPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKP 736

Query: 964  -------SQAIAEKQPSQ---EVKMEAKMEVDQP-EPADTQ---PEDISESKVEDCKMES 1009
                   S+A+A  + SQ   EVK++    V QP E A T+   P++  E+++   K+E 
Sbjct: 737  IVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEE 796

Query: 1010 TETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKP----EELRQALMPTLE-- 1063
             +   R   LK +    + Q      +      Q +++++ P    E+  QAL P+    
Sbjct: 797  -QKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNG 855

Query: 1064 --------ALYRQD 1069
                    A  RQ+
Sbjct: 856  NPLLPFPGAQVRQN 869



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 115/462 (24%), Positives = 166/462 (35%), Gaps = 67/462 (14%)

Query: 1907 PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMG 1966
            P  PP   Q P P PPP   +    + +    Q  +        P+QH   P  P  P G
Sbjct: 310  PTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLL--------PVQH---PHHPSPPQG 358

Query: 1967 MNPPPMTRGPSGHLEPGMGPTGMQQQP------PWSQGGLPQPQQLQ----SGMPRPAMM 2016
            M+ PP    P   + P   P    QQP      P  +G +  P Q+        PRPA+ 
Sbjct: 359  MHMPPQLETPRMMMTP---PPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG 415

Query: 2017 SVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHA 2076
                 G P    PQ   G V      P + SQ     L    R+P  P  +      +  
Sbjct: 416  PQRFPGPP--EFPQHTPGPV------PNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSG 467

Query: 2077 NPQLLA-AFIKQRAAKYANSNP------QPIPGQPGMPQGQPGL------QPPTMPGQQG 2123
             P+  +  F++QR+       P       P+P Q  +P  QPG       Q P  P ++ 
Sbjct: 468  EPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP 527

Query: 2124 VHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDI- 2182
            V   PA+Q   P+  G+     P     +   PP     P   Q  +  +T P+    + 
Sbjct: 528  V--RPALQPPGPV--GILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLH 583

Query: 2183 ----LRRQQMMQQQQQQGAGPGIGPGMANHN---QFQQP--QGVGYPPQQQQRMQHHMQQ 2233
                   Q   QQ QQQ       P    H    Q Q P      +PPQ Q    HH   
Sbjct: 584  PPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLS 643

Query: 2234 MQQGNMGQIGQ---LPQALGAEAGAS---LQAYQQRLLQQQMGSPVQPNPMSPQQHMLPN 2287
            +    +  + Q    P    A+  AS   +Q  Q++ L+    S  Q     P Q M P 
Sbjct: 644  VPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTS--QNVSKRPMQQMQPT 701

Query: 2288 QAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSP 2329
              ++ +L+   I  S   ++ S +   +P  Q +P  S+  P
Sbjct: 702  APRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPP 743



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 117/454 (25%), Positives = 147/454 (32%), Gaps = 113/454 (24%)

Query: 1957 PPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM 2016
            PP+ P AP    PPP                  QQQP  S   L QPQ LQ  +P    +
Sbjct: 313  PPVVPQAPPPPPPPP------------------QQQPIRS---LFQPQPLQPLLP----V 347

Query: 2017 SVAQHGQP---LNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSI 2073
                H  P   ++M PQ    ++ ++P                    P +P Q + +   
Sbjct: 348  QHPHHPSPPQGMHMPPQLETPRMMMTP-------------------PPVTPQQPKNI--- 385

Query: 2074 LHANPQLLAAFIK--QRAAKYANSNPQP------IPGQPGMPQGQPG------LQPPTMP 2119
             H NP      +   Q       S P+P       PG P  PQ  PG       QPP +P
Sbjct: 386  -HINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLP 444

Query: 2120 GQQGVHSNPAMQNMNPMQAGVQ-RAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQ 2178
             Q    + P  Q+ +P   GV      P     +Q  PP     P    +N +H      
Sbjct: 445  LQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPP--PPPPTLLNSSHPVPTQS 502

Query: 2179 FRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGN 2238
                 +      QQ QQ   P   P        Q P  VG        + H  Q      
Sbjct: 503  PLPFTQPGPAFNQQGQQPVFPRERPVRP---ALQPPGPVG--------ILHFSQPGSATT 551

Query: 2239 MGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPV----QPNPMSPQQHMLPNQAQSPHL 2294
               I      L       L  + Q  LQ  +  P+    QP P  PQQ   P Q Q PH 
Sbjct: 552  RPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQP-PPQHQPPH- 609

Query: 2295 QGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAA 2354
                            QP   P PQ QPP   P P+  PQ   HH     S P P L+  
Sbjct: 610  ----------------QPPHQPPPQHQPPPQHP-PQHPPQHQHHHHHHHLSVPPPPLM-- 650

Query: 2355 QANPMEQGHF------ASPDQNSMLSQLASNPGM 2382
               PM Q  F      A P  +S   Q     G+
Sbjct: 651  ---PMSQPQFRPHVQTAQPQASSSRMQCPQRQGL 681



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 141/667 (21%), Positives = 211/667 (31%), Gaps = 130/667 (19%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQP---------QPTPPNSMPPYLPRTQAAG 1894
            +Q  P P P  PT      P   Q+P P +QP         QP  P   P   P  Q  G
Sbjct: 478  EQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP-VRPALQPPG 536

Query: 1895 PVS----QGKAAGQVTPPTPPQTAQPPLPGP---------------------PPAAVEMA 1929
            PV         +    P  PP+  QP LPGP                     PP      
Sbjct: 537  PVGILHFSQPGSATTRPFIPPR--QPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQP 594

Query: 1930 MQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGH----LEPGMG 1985
             Q Q+    Q Q  H    Q P QHQ PP  P      +PP        H      P + 
Sbjct: 595  QQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP----PQHPPQHQHHHHHHHLSVPPPPLM 650

Query: 1986 PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGT 2045
            P    Q  P  Q    QPQ   S M  P    +  +    N++ +P      + P  P  
Sbjct: 651  PMSQPQFRPHVQ--TAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP---MQQMQPTAPRN 705

Query: 2046 VSQQAL----QNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIP 2101
             + + L     +++    S  S     QV  I+ A+P   A      A   ++     + 
Sbjct: 706  SNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAV-----AGSRSSQGKTEVK 760

Query: 2102 GQPGMPQGQPGLQPPT-----------------MPGQQGVHSNPAMQN--MNPMQAGVQR 2142
             +P  P  QP  +  T                 +  Q+ +      Q       QAG ++
Sbjct: 761  VKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARK 820

Query: 2143 AGLPQQQPQQQLQ----PPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAG 2198
              L ++  QQQ Q    PP      QA   +  +      F     RQ +  +   +   
Sbjct: 821  KELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQD 880

Query: 2199 PGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQ 2258
              I       + F           QQ +   H++Q +     Q   L + L  +      
Sbjct: 881  VSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPA---D 937

Query: 2259 AYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQ------- 2311
              +  + Q    + +Q  P   +  +        +  G   P+ +S++VR  +       
Sbjct: 938  VEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPH-ISSKVRVIKLSGGGGE 996

Query: 2312 ------PVPSPRPQSQPPHSSPSPRMQ--------PQPSPHHVSPQTSSP-HPGLVAAQ- 2355
                  P   P+   QPP   P P  +         QP      P   SP  PG+ + Q 
Sbjct: 997  SDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQG 1056

Query: 2356 ----------------ANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDN 2399
                            A PM +G      QN  + +    P + ++ G S+     ST +
Sbjct: 1057 IHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSS-----STTD 1111

Query: 2400 SDLNSNL 2406
            + L S L
Sbjct: 1112 AQLKSLL 1118



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 116/453 (25%), Positives = 146/453 (32%), Gaps = 84/453 (18%)

Query: 1823 QQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPT----TPQTPQPTSQPQ-- 1876
            Q+ +   R      R  ++  Q  +    P  P  P  QQP      PQ  QP    Q  
Sbjct: 291  QRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHP 350

Query: 1877 --PTPPNS--MPPYL--PRTQAAGPVSQGKAAGQV--------TPPTPPQTAQPPLPGPP 1922
              P+PP    MPP L  PR     P    +    +        T  TP Q    P+P  P
Sbjct: 351  HHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQP 410

Query: 1923 PAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPP------PMTRGP 1976
              AV      QR         H      P     PP  P+      PP      P   G 
Sbjct: 411  RPAVGP----QRFPGPPEFPQHTP-GPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGV 465

Query: 1977 SGHLEPGMGPTGM---QQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGL 2033
            SG  EP   P+ +   Q+ PP      P P  L S  P P      Q   P    P P  
Sbjct: 466  SG--EPRF-PSHLFLEQRSPPPPP---PPPTLLNSSHPVP-----TQSPLPFTQ-PGPAF 513

Query: 2034 GQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYA 2093
             Q G  P+ P            R +R    P     +L            FI  R     
Sbjct: 514  NQQGQQPVFPRE----------RPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFL- 562

Query: 2094 NSNPQPIPGQPGMP-------QG--QPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAG 2144
                 P PGQP +P       QG   P L PP  P  Q     P  Q+  P Q       
Sbjct: 563  -----PGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQ------- 610

Query: 2145 LPQQQPQQQLQPP--MGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIG 2202
             P  QP  Q QPP       P   Q + +H+ +      ++   Q   +   Q A P   
Sbjct: 611  -PPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQP--- 666

Query: 2203 PGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQ 2235
               ++  Q  Q QG+ +    Q   +  MQQMQ
Sbjct: 667  QASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQ 699



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 73/276 (26%), Positives = 95/276 (34%), Gaps = 49/276 (17%)

Query: 844  HTPPSIGAQQPPATTIPAPVPTPPAMPPGP---QSQALHP-----------PPRQTPTPP 889
            H P  +  Q P     P P P PP   P     Q Q L P           PP+    PP
Sbjct: 304  HRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPP 363

Query: 890  TTQLPQQVQPSLPAAPSADQPQQQPRS---QQSTAASVPTPTAPLLPPQPATPLSQPAVS 946
              + P+ +    P  P      QQP++         +V TP    L P P+ P  +PAV 
Sbjct: 364  QLETPRMMMTPPPVTP------QQPKNIHINPHFKGTVVTPVQVPLLPVPSQP--RPAVG 415

Query: 947  ---IEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVE 1003
                 G    P  T     NS +   + P Q+           P P D  P  +  S  E
Sbjct: 416  PQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRA------PPPPQDRDPFFLGVSG-E 468

Query: 1004 DCKMESTETEERS----TELKTEIKEEEDQPSTSA---TQSSPAPGQSKKKIFKPEE--L 1054
                     E+RS        T +      P+ S    TQ  PA  Q  ++   P E  +
Sbjct: 469  PRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV 528

Query: 1055 RQALMP--TLEALYRQDPESL---PFRQPVDPQLLG 1085
            R AL P   +  L+   P S    PF  P  P L G
Sbjct: 529  RPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPG 564



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 59/228 (25%), Positives = 84/228 (36%), Gaps = 52/228 (22%)

Query: 1818 LQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTS---Q 1874
            +Q++ QQ + L+    +  RT    Q Q L    P  P     ++P  PQTP+  S   +
Sbjct: 900  MQYQGQQMKALKHLRQT--RTVPQSQTQPLHKVLPIKPADV--EEPAVPQTPRVASIQGR 955

Query: 1875 PQPTPPNSMPPYLPRTQAAG---------------PVSQGKAAGQVTPPTPPQ-TAQPPL 1918
            PQ T P        RT + G                   G++ G   P   PQ   QPP 
Sbjct: 956  PQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPE 1015

Query: 1919 PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNP-PPMTRGPS 1977
             GP PA        ++   T+  +            Q PP  P  P   +P PP  +   
Sbjct: 1016 VGPQPA--------RKVTLTRGGL------------QQPPHLPAGPHAHSPVPPGIKSIQ 1055

Query: 1978 GHLEPG----MGPTGMQQQPPWSQGGL-PQPQQLQ--SGMPRPAMMSV 2018
            G + P     M   G     P  +G L P  Q L+     P+P ++SV
Sbjct: 1056 G-IHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSV 1102


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 68/244 (27%), Positives = 107/244 (43%), Gaps = 17/244 (6%)

Query: 916  SQQSTAASVPTPTAPLLPPQ--PATPLSQPAVSIEGQVSNP--PSTSSTEVNSQAIAEKQ 971
            + Q  A S  + TA   PP   P T L+ P  S+   +S+P   S  S      A+    
Sbjct: 212  AHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSV---ISSPLLKSLHSAGPPLLAVTAAP 268

Query: 972  PSQEVK----MEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKE-E 1026
            P+Q +     ++ K +   P P          S     + ++        E    IK   
Sbjct: 269  PAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPR 328

Query: 1027 EDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
            +D P +     S   G+  +++     + + L+    A Y     + PF +PVD   LG+
Sbjct: 329  KDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAY-----AWPFYKPVDASALGL 383

Query: 1087 PDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLS 1146
             DY DI+K PMDLST+KRK++   Y++  ++  D+ LMF+N + YN     V     KL 
Sbjct: 384  HDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQ 443

Query: 1147 EVFE 1150
            +VFE
Sbjct: 444  DVFE 447



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 43/132 (32%), Positives = 70/132 (53%), Gaps = 4/132 (3%)

Query: 1030 PSTSATQSSPAPGQ---SKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
            P+   T ++P P +    KK      +L+      ++AL++    + PFRQPVD   LG+
Sbjct: 52   PALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQ-FAWPFRQPVDAVKLGL 110

Query: 1087 PDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLS 1146
            PDY  I+K PMD+ TIKR+L+   Y    + + D   MF N ++YN+ T  +      L 
Sbjct: 111  PDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLE 170

Query: 1147 EVFEQEIDPVMQ 1158
            ++F Q++  + Q
Sbjct: 171  KIFLQKVASMPQ 182



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 68/298 (22%), Positives = 111/298 (37%), Gaps = 48/298 (16%)

Query: 826  ALHQNSPSPVPSRTPTPHHTP--PSIGAQQPPATTIPAPV----PTPPAMPPG---PQSQ 876
            +LH   P P+ + T  P   P     G ++   TT P P     P  PA PPG   P++ 
Sbjct: 253  SLHSAGP-PLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAA 311

Query: 877  ALHPPPRQTPTP---PTTQLP---QQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAP 930
             L P  R++  P   P   LP   QQ Q S     S          ++  +        P
Sbjct: 312  RLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWP 371

Query: 931  LLPPQPATPLS-----------QPAVSIEGQVSNPPSTSSTE-------VNSQAIAEKQP 972
               P  A+ L                +++ ++ N     + E       + S       P
Sbjct: 372  FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP 431

Query: 973  SQEVKMEAKMEVD---------QPEPADTQPEDISESKVEDCKMESTET--EERSTELKT 1021
              +V   A+   D           EP +  P  +S +        S+E+  EE S+E  +
Sbjct: 432  DHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSS 491

Query: 1022 EIKEEEDQPSTSATQSSPAPGQSKK--KIFKPEELRQALMPTLEALYRQDPESLPFRQ 1077
            E +EEED+      +S  +  + ++  ++ + +E  +A+   L AL  Q P S P R+
Sbjct: 492  EEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAAL-SQGPISKPKRK 548



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 8/100 (8%)

Query: 841 TPHHTPPSIGAQQPPATTIPAP-VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP 899
           T  H  P++ +    A   P P +PT     P       HP    +P   +         
Sbjct: 210 TSAHQVPAVSSVSHTALYTPPPEIPTTVLNIP-------HPSVISSPLLKSLHSAGPPLL 262

Query: 900 SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939
           ++ AAP A    ++   ++    + PTPTA L P  PA+P
Sbjct: 263 AVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASP 302



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 1/82 (1%)

Query: 1847 LPSPTPATPTTPTG-QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQV 1905
            L +P P  PTT      P+   +P   S     PP       P  Q        K     
Sbjct: 226  LYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADT 285

Query: 1906 TPPTPPQTAQPPLPGPPPAAVE 1927
            T PTP     P  P  PP ++E
Sbjct: 286  TTPTPTAILAPGSPASPPGSLE 307



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 1514 EESIKELEQEEEERKREENTSNESTDVTKGDSKNAKK-----KNNKKTSKNKSSLSRGNK 1568
            EES  E   EEEE + EE+   E ++ +  + + A +     +  +   +  ++LS+G  
Sbjct: 483  EESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPI 542

Query: 1569 KKPGMPNVSNDLSQKLYATMEKHK 1592
             KP       +  +K  A  EKH+
Sbjct: 543  SKPKRKREKKEKKKKRKA--EKHR 564


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 68/244 (27%), Positives = 107/244 (43%), Gaps = 17/244 (6%)

Query: 916  SQQSTAASVPTPTAPLLPPQ--PATPLSQPAVSIEGQVSNP--PSTSSTEVNSQAIAEKQ 971
            + Q  A S  + TA   PP   P T L+ P  S+   +S+P   S  S      A+    
Sbjct: 212  AHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSV---ISSPLLKSLHSAGPPLLAVTAAP 268

Query: 972  PSQEVK----MEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKE-E 1026
            P+Q +     ++ K +   P P          S     + ++        E    IK   
Sbjct: 269  PAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPR 328

Query: 1027 EDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
            +D P +     S   G+  +++     + + L+    A Y     + PF +PVD   LG+
Sbjct: 329  KDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAY-----AWPFYKPVDASALGL 383

Query: 1087 PDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLS 1146
             DY DI+K PMDLST+KRK++   Y++  ++  D+ LMF+N + YN     V     KL 
Sbjct: 384  HDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQ 443

Query: 1147 EVFE 1150
            +VFE
Sbjct: 444  DVFE 447



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 43/132 (32%), Positives = 70/132 (53%), Gaps = 4/132 (3%)

Query: 1030 PSTSATQSSPAPGQ---SKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
            P+   T ++P P +    KK      +L+      ++AL++    + PFRQPVD   LG+
Sbjct: 52   PALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQ-FAWPFRQPVDAVKLGL 110

Query: 1087 PDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLS 1146
            PDY  I+K PMD+ TIKR+L+   Y    + + D   MF N ++YN+ T  +      L 
Sbjct: 111  PDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLE 170

Query: 1147 EVFEQEIDPVMQ 1158
            ++F Q++  + Q
Sbjct: 171  KIFLQKVASMPQ 182



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 68/298 (22%), Positives = 111/298 (37%), Gaps = 48/298 (16%)

Query: 826  ALHQNSPSPVPSRTPTPHHTP--PSIGAQQPPATTIPAPV----PTPPAMPPG---PQSQ 876
            +LH   P P+ + T  P   P     G ++   TT P P     P  PA PPG   P++ 
Sbjct: 253  SLHSAGP-PLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAA 311

Query: 877  ALHPPPRQTPTP---PTTQLP---QQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAP 930
             L P  R++  P   P   LP   QQ Q S     S          ++  +        P
Sbjct: 312  RLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWP 371

Query: 931  LLPPQPATPLS-----------QPAVSIEGQVSNPPSTSSTE-------VNSQAIAEKQP 972
               P  A+ L                +++ ++ N     + E       + S       P
Sbjct: 372  FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP 431

Query: 973  SQEVKMEAKMEVD---------QPEPADTQPEDISESKVEDCKMESTET--EERSTELKT 1021
              +V   A+   D           EP +  P  +S +        S+E+  EE S+E  +
Sbjct: 432  DHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSS 491

Query: 1022 EIKEEEDQPSTSATQSSPAPGQSKK--KIFKPEELRQALMPTLEALYRQDPESLPFRQ 1077
            E +EEED+      +S  +  + ++  ++ + +E  +A+   L AL  Q P S P R+
Sbjct: 492  EEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAAL-SQGPISKPKRK 548



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 8/100 (8%)

Query: 841 TPHHTPPSIGAQQPPATTIPAP-VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP 899
           T  H  P++ +    A   P P +PT     P       HP    +P   +         
Sbjct: 210 TSAHQVPAVSSVSHTALYTPPPEIPTTVLNIP-------HPSVISSPLLKSLHSAGPPLL 262

Query: 900 SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATP 939
           ++ AAP A    ++   ++    + PTPTA L P  PA+P
Sbjct: 263 AVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASP 302



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 1/82 (1%)

Query: 1847 LPSPTPATPTTPTG-QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQV 1905
            L +P P  PTT      P+   +P   S     PP       P  Q        K     
Sbjct: 226  LYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADT 285

Query: 1906 TPPTPPQTAQPPLPGPPPAAVE 1927
            T PTP     P  P  PP ++E
Sbjct: 286  TTPTPTAILAPGSPASPPGSLE 307



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 1514 EESIKELEQEEEERKREENTSNESTDVTKGDSKNAKK-----KNNKKTSKNKSSLSRGNK 1568
            EES  E   EEEE + EE+   E ++ +  + + A +     +  +   +  ++LS+G  
Sbjct: 483  EESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPI 542

Query: 1569 KKPGMPNVSNDLSQKLYATMEKHK 1592
             KP       +  +K  A  EKH+
Sbjct: 543  SKPKRKREKKEKKKKRKA--EKHR 564


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 110/422 (26%), Positives = 143/422 (33%), Gaps = 47/422 (11%)

Query: 672  GPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTP 731
            G  + +P     S+   P  S  R     +  PR        +   +   +PP V   TP
Sbjct: 231  GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV---TP 287

Query: 732  PLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ--GMNVTNIPLAPSSGQA 789
            P +       P + +P     P     S     LP T   S       T +PLAP S  A
Sbjct: 288  PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347

Query: 790  PVS-QAQMSSSSCPVNSPIMPPGS---QGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT 845
            P S Q   S  + P +      GS   Q +H   P  P   L    P   P+    P   
Sbjct: 348  PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407

Query: 846  PPSIGAQQPPATTIPAPVPTPP------------AMPPGPQSQALHPPPRQTPTPPTTQL 893
            PPS  A  PP + +  P P  P            + PP P  QA   PP   P  P+   
Sbjct: 408  PPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466

Query: 894  PQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA---------------PLLPPQPAT 938
            P Q  PSL AAP    P   P S   + ++ P P A               P  PP  AT
Sbjct: 467  PSQAPPSL-AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525

Query: 939  P----LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQP 994
            P    L  P  S  GQ    PS S   +    +A   P     + A +    P P    P
Sbjct: 526  PPLQALPSPPASFPGQAPFSPSAS---LPMSPLATPPPQAPPVLAAPLLQVPPSP-PASP 581

Query: 995  EDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSP-APGQSKKKIFKPEE 1053
               +  +      +++ +  R T             S S+T S P   G S      PEE
Sbjct: 582  TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641

Query: 1054 LR 1055
            LR
Sbjct: 642  LR 643



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 85/318 (26%), Positives = 109/318 (34%), Gaps = 59/318 (18%)

Query: 1844 QQGLPSPTPATP---------TTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
            Q   P   PATP          TP    P +P  P P+ Q  P+PP + PP    T    
Sbjct: 314  QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-PSLQTLPSPP-ATPPSQATTSLGS 371

Query: 1895 PVSQGKAAGQVTPP----------TPPQTAQPPLPGP--PPAAVEMAMQIQRAAETQRQM 1942
            P  Q   +   +PP           PP  A PPL  P  PPA+  ++     + +    +
Sbjct: 372  PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431

Query: 1943 AHVQIFQRPIQ--HQMPPMTPMAPMGMNP------PPMTRGPSGHLEPGMGPTGMQQQPP 1994
            A V + Q P       P   P +P    P      PP    PS    P   P      PP
Sbjct: 432  A-VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490

Query: 1995 WSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGIS--PLKPGTVSQQALQ 2052
             S    P PQ      P P      Q  +P   AP P L    +   P  P +   QA  
Sbjct: 491  MSPSATPPPQ-----APPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQA-- 542

Query: 2053 NLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPG 2112
                   SPS+ L    + +     P +LAA + Q             P  P  P  Q  
Sbjct: 543  -----PFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-----------PSPPASPTLQAP 586

Query: 2113 LQPPTMPGQQGVHSNPAM 2130
             +PPT PG     S P +
Sbjct: 587  RRPPT-PGPDTSVSGPRL 603



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 83/305 (27%), Positives = 102/305 (33%), Gaps = 89/305 (29%)

Query: 720 MAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ-GMNVT 778
           +  PP+ P  TPP Q    LA P    PP    P    P +     P  Q P+   +++ 
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPP---SPPASPPLSP-LATPSPQAPNALAVHLL 436

Query: 779 NIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGS-HIHCPQLPQPALHQNSPSPVPS 837
             P +P    +P  QA  S  + P  SP   P SQ    +  P L  P     SP   PS
Sbjct: 437 QAPFSPPP--SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494

Query: 838 RTPTPHHTPPSIGA---------QQPPATTIPA--PVPTPPAMPPG----------PQSQ 876
            TP P   PP             Q PPA   P    +P+PPA  PG          P S 
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 877 ALHPPPRQTPTPPTTQLPQ-QVQPSLPAAPSADQPQQQP--------------------- 914
              PPP+    PP    P  QV PS PA+P+   P++ P                     
Sbjct: 555 LATPPPQ---APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611

Query: 915 -----RSQQST------------------------------AASVPTPTAPLLPPQPATP 939
                RS  ST                              AA+ P P A L    PA  
Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671

Query: 940 LSQPA 944
              PA
Sbjct: 672 SRGPA 676



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 73/282 (25%), Positives = 98/282 (34%), Gaps = 50/282 (17%)

Query: 1855 PTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTA 1914
            P +P  Q P +P    P S P  TPP+  PP L     A P  Q   +   +PP  P +A
Sbjct: 443  PPSPPVQAPFSPPASPPVS-PSATPPSQAPPSL-----AAPPLQVPPSPPASPPMSP-SA 495

Query: 1915 QPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTR 1974
             PP   PPP A                         P+Q   PP  P AP  +  PP+  
Sbjct: 496  TPPPQAPPPLAAP-----------------------PLQLAKPP--PQAPPALATPPLQA 530

Query: 1975 GPSGHLE-PGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGL 2033
             PS     PG  P       P S    P PQ        P +++      P +    P L
Sbjct: 531  LPSPPASFPGQAPFSPSASLPMSPLATPPPQ-------APPVLAAPLLQVPPSPPASPTL 583

Query: 2034 GQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYA 2093
             Q    P  PG  +  +   L   L +P  P    +  S   + P L         +  A
Sbjct: 584  -QAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDLAG------HSSSA 635

Query: 2094 NSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNP 2135
             S P+ + G    P+G     PP  P  +    +PA  +  P
Sbjct: 636  TSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRGP 675



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 124/554 (22%), Positives = 169/554 (30%), Gaps = 76/554 (13%)

Query: 1833 ASMQRTGVVGQQQGLPSPTP-ATPTTPT----------GQQPTTPQTPQPTSQPQPTPPN 1881
            A  +R+   G + GLP P P A P  PT           +  TT  +P    +P      
Sbjct: 175  AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 1882 SMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQ 1941
              P     + +A P+S    +G     TP   A P  P P         Q+       R+
Sbjct: 235  QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT----PPRK 290

Query: 1942 MAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLP 2001
             A   +          P    A     PP +   P          T +   PP S    P
Sbjct: 291  DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP-SPSAPP 349

Query: 2002 QPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNL-LRTLRS 2060
              Q L S    P   +    G P   A    L    +SPL   T   QA   L L  L++
Sbjct: 350  SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL--ATPPPQAPPALALPPLQA 407

Query: 2061 PSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPG 2120
            P SP     +  +   +PQ   A          +  P P    P  P   P + P   P 
Sbjct: 408  PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 2121 QQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFR 2180
             Q   S  A     P          P   P  Q  PP+     Q  +        P Q  
Sbjct: 468  SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP-------PPQAP 520

Query: 2181 DILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMG 2240
              L    +        + PG  P   + +    P  +  PP Q                 
Sbjct: 521  PALATPPLQALPSPPASFPGQAPFSPSASLPMSP--LATPPPQA---------------- 562

Query: 2241 QIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIP 2300
                 P  L A            LLQ     P  P   +P++   P    S  + G ++ 
Sbjct: 563  -----PPVLAAP-----------LLQVPPSPPASPTLQAPRRPPTPGPDTS--VSGPRLT 604

Query: 2301 NSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPME 2360
             +L+         P P P   PP  SPS  +       H S  TS+P   L    + P E
Sbjct: 605  LALA---------PGPPP---PPSRSPSSTLSGPDLAGHSSSATSTPEE-LRGYDSGP-E 650

Query: 2361 QGHFASPDQNSMLS 2374
             G  ASP  ++ L+
Sbjct: 651  GGAAASPPPDAELA 664



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 23/241 (9%)

Query: 659 PNAAGMVPVSMNPGPNMGQPQPGMTS--NGPLPDPSMIRGSVPNQMMPRITPQSGLNQFG 716
           P A   + V +   P    P P + +  + P   P     + P+Q  P +       Q  
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP--LQVP 482

Query: 717 QMSMAQPPIVPRQTPPLQHHGQLAQPGA--LNPPMGYGPRMQQPSNQGQFLPQTQFPSQG 774
               A PP+ P  TPP Q    LA P      PP    P +  P  Q    P   FP Q 
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 542

Query: 775 MN-----------VTNIPLAPSSGQAPVSQAQMSSSSCP-VNSPIMPPG-SQGSHIHCPQ 821
                         T  P AP    AP+ Q   S  + P + +P  PP     + +  P+
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602

Query: 822 LPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPP 881
           L         P P PSR+P+   + P +      AT+ P  +    + P G    A  PP
Sbjct: 603 LTLALAP--GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG--GAAASPP 658

Query: 882 P 882
           P
Sbjct: 659 P 659



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 129/585 (22%), Positives = 187/585 (31%), Gaps = 108/585 (18%)

Query: 1853 ATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQ---GKAAGQVTPPT 1909
            A   TP  + P    TP+P   P+P PP + P  L    AAG V +    + AG +   T
Sbjct: 12   AAARTPAARAPGL-LTPRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 1910 PPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNP 1969
             P++A  P  GP           + A  + R  A      RP         P +  G   
Sbjct: 70   IPESA--PRAGPT----------RSAGTSSRNPA-----SRP---------PASGRGERA 103

Query: 1970 PPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL----PQPQQLQSGMPRPAMMSVAQHGQPL 2025
            PP      G +      +G  +  P  Q GL     +          P   +++   +  
Sbjct: 104  PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163

Query: 2026 NMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFI 2085
               P PG     ++       ++  L     + R P  P +  +                
Sbjct: 164  TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR-PRPPTEGPR---------------- 206

Query: 2086 KQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTM-----------------PGQQGVHSNP 2128
            K  ++   +S  +P P     P    GLQ P                   P  +G    P
Sbjct: 207  KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 2129 AMQNMNPMQAGVQRAGLPQQQPQQQ-----LQP----PMGGMSPQAQQMNMNHNTMPSQF 2179
            A  +  P   G+Q    PQ  P ++     L P    P+   SP A   +    T+P+  
Sbjct: 267  AHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325

Query: 2180 RDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQ------QQRMQHHMQQ 2233
                   Q+          P   P +        P     PP Q         +Q     
Sbjct: 326  HSSSLTCQLATPLPLAPPSPSAPPSLQT-----LPSPPATPPSQATTSLGSPTLQATHSF 380

Query: 2234 MQQGNMGQIGQLP-QALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQ---HMLPNQA 2289
            +    +  +   P QA  A A   LQA         +     P+P +P     H+L    
Sbjct: 381  LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440

Query: 2290 QSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP---HHVSPQTSS 2346
              P     Q P S      SP   PS  P SQ P S  +P +Q  PSP     +SP  + 
Sbjct: 441  SPPPSPPVQAPFS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497

Query: 2347 P--------HPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMA 2383
            P         P L  A+  P      A+P   ++ S  AS PG A
Sbjct: 498  PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 542



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 76/348 (21%), Positives = 121/348 (34%), Gaps = 73/348 (20%)

Query: 784  PSSGQAPVSQAQMSSSSCPVNSPIM--------PPGSQGSHIHCPQLPQPALHQNSPSPV 835
            P+SG+   +    ++S  PV+SP          P G +G  I   +     + +   +  
Sbjct: 95   PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE----TVARGKATEA 150

Query: 836  PSRT------------PTPHHTPPSIGAQQPPA-TTIPAPVPTPPAMPPGPQSQALHPPP 882
            P R+            PTP    P++  +   A T +  P P P A P  P        P
Sbjct: 151  PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-----GP 205

Query: 883  RQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP-------------TPTA 929
            R++ +  +     +  P+    PSA    Q+P S+  ++++ P             TP A
Sbjct: 206  RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 930  PLLPPQP------------ATPLSQPAVSIEGQVSNPP---STSSTEVNSQAIAEKQPSQ 974
            P  P QP             TP  + A    G +S+ P    + S  + SQA     P+ 
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA-PPTLPAT 324

Query: 975  EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSA 1034
                    ++  P P          S        +T   + +T L          P+  A
Sbjct: 325  PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL--------GSPTLQA 376

Query: 1035 TQS-SPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1081
            T S  P+P  S      P+      +P L+A     P S P   P+ P
Sbjct: 377  THSFLPSPPLSPLATPPPQAPPALALPPLQA-----PPSPPASPPLSP 419



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 44/220 (20%)

Query: 1845 QGLPSPTPA----TPTTPTGQQPTTP-QTPQPTSQP---------QPTPPNSMPPYLPR- 1889
            Q LPSP  +     P +P+   P +P  TP P + P          P+PP S     PR 
Sbjct: 529  QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588

Query: 1890 -------TQAAGP-VSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQ 1941
                   T  +GP ++   A G   PP P ++    L GP     ++A     A  T  +
Sbjct: 589  PPTPGPDTSVSGPRLTLALAPG--PPPPPSRSPSSTLSGP-----DLAGHSSSATSTPEE 641

Query: 1942 MAHVQIFQRPIQHQMPPMTPMAPM-GMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
            +              PP  P A +   +P   +RGP+    P +   G    P      L
Sbjct: 642  LRGYDSGPEGGAAASPP--PDAELAACHPAAWSRGPA----PPLAFRGAPGAP------L 689

Query: 2001 PQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP 2040
            P P     G     + ++ +   P +  P PG    G SP
Sbjct: 690  PWPPATGPG-SADGLCTIYETEGPESATPAPGALDPGPSP 728


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 130/534 (24%), Positives = 189/534 (35%), Gaps = 112/534 (20%)

Query: 1847 LPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVT 1906
            LPSP+      PT  +P   Q     SQP P  P + P  L +  A  P       G V 
Sbjct: 298  LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-------GTVK 350

Query: 1907 PPT-PPQTAQPPL----PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTP 1961
            PP  PP T +PP     P  PPA        Q  +E            +P   Q  P   
Sbjct: 351  PPVQPPGTTKPPAQPLGPAKPPAQ-------QTGSE------------KPSSEQPGPKAL 391

Query: 1962 MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ----QPPWSQGGLPQPQQLQSGMPRPAMMS 2017
              P                 PG+G T  QQ    +PP  Q G P+P   Q G+  PA   
Sbjct: 392  AQP-----------------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434

Query: 2018 VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
                G       QPG G++      PG  S Q         + P       Q        
Sbjct: 435  ----GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 2078 PQLLAAFIKQRAAKYANSNP---QPIPGQPG----MPQGQPGLQPPTMPGQQGVHSNPAM 2130
            PQ      +  +AK  +  P   +P P QPG     PQ QPG   P  P QQ   + P+ 
Sbjct: 491  PQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ-QPGSTKP--PSQQPGSAKPSA 541

Query: 2131 QNMNPMQAGVQRAGLPQQQ--PQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQM 2188
            Q  +P +   Q++  P  Q    + LQPP   +SP A+Q       +P     +    ++
Sbjct: 542  QQPSPAKPSAQQSTKPVSQTGSGKPLQPPT--VSPSAKQ--PPSQGLPKTICPLCNTTEL 597

Query: 2189 MQQQQQQGAGPGIGPGMANHNQFQQPQGV-----GYPPQQQQRMQHHMQQMQQGNMGQIG 2243
            +             P  AN N   + Q       G+ P        H+ ++++  +    
Sbjct: 598  LLHV----------PEKANFNTCTECQTTVCSLCGFNPNP------HLTEVKEW-LCLNC 640

Query: 2244 QLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQ-QHMLPNQAQSPHLQGQQIPNS 2302
            Q+ +ALG +      + Q +L    + +    +  SPQ Q   P +  +P          
Sbjct: 641  QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK--------- 691

Query: 2303 LSNQVRSPQPVPSPRPQSQPP-HSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQ 2355
              +  ++P+P   P    QP  H SPS + +  P    +S       P + + Q
Sbjct: 692  -QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 116/470 (24%), Positives = 170/470 (36%), Gaps = 111/470 (23%)

Query: 719  SMAQPPI---VPRQTPPLQHHGQLAQPGALNPPMGYG----PRMQQPSNQGQFLPQTQFP 771
            S ++PPI    P + P  Q   + +QPG   PP        P  QQP   G   P  Q P
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP---GTVKPPVQPP 356

Query: 772  SQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPI-MPPG---------------SQGS 815
                     PL P+   A  + ++  SS  P    +  PPG               +Q  
Sbjct: 357  GTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415

Query: 816  HIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQ--------------PPATTIPA 861
                P   QP L   + +P P++TP     P  I AQQ               P + +P 
Sbjct: 416  GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475

Query: 862  PVPTPPAMP----PGPQSQALHPPPRQTP--TPPTTQLPQQVQPSLPAAPSADQPQQQPR 915
            P   PP  P    P PQ      PP Q P  T P  Q P   +PS     S   P QQP 
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535

Query: 916  SQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
            S + +A   P+P  P    Q   P+SQ      G+   PP+ S +       A++ PSQ 
Sbjct: 536  SAKPSAQQ-PSPAKP-SAQQSTKPVSQTG---SGKPLQPPTVSPS-------AKQPPSQG 583

Query: 976  VKM-------EAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK-------- 1020
            +           ++ +  PE A+      +E +   C +         TE+K        
Sbjct: 584  LPKTICPLCNTTELLLHVPEKANF--NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQ 641

Query: 1021 -----------------TEIKEEEDQPSTSATQSSPAPGQS--KKKIFKPEELRQA---- 1057
                              ++K      +++ ++SSP P Q+  KK     ++L +A    
Sbjct: 642  MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK 701

Query: 1058 ------LMPTL----EALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPM 1097
                    PTL     A  +Q PE+    +P  P+   +P   D  K+P+
Sbjct: 702  KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD--KAPV 749



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 222/1000 (22%), Positives = 335/1000 (33%), Gaps = 170/1000 (17%)

Query: 107  QAQQSSPGLGLINSMVKSPMTQAGLTSP-NMGMGTSGPN------QGPTQSTGMMNSPVN 159
            +A    PG+G      K+P  Q G   P    +GT  P       Q P ++ G   +PV 
Sbjct: 389  KALAQPPGVG------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 160  QPAMGMNTGMNAGMNPGMLAAGN-GQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNL 218
            QP  G      AG  PG  +A   G    P+Q+       G  +   Q P P        
Sbjct: 443  QPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQL------PGPAKPPPQQPGPAK------ 488

Query: 219  LTEPLQQGSPQMGGQT-GLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTK 277
               P Q GS +   Q  G   P P + G    P+P     T+ P QQ G++    Q  + 
Sbjct: 489  -PPPQQPGSAKPPSQQPGSTKPPPQQPGPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSP 546

Query: 278  TVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKL 337
               S   S   + +    G G P      +P  +QP      +QG+        P+    
Sbjct: 547  AKPSAQQSTKPVSQT---GSGKPLQPPTVSPSAKQPP-----SQGL--------PKTICP 590

Query: 338  IQQQLVLLLHAHKCQRREQAN-GEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASS 396
            +     LLLH       E+AN     +C    C       N   H    K     +C   
Sbjct: 591  LCNTTELLLHVP-----EKANFNTCTECQTTVCSLCG--FNPNPHLTEVKEWLCLNCQMK 643

Query: 397  RQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTV 456
            R +            P          K    P+ T + V   +P      QQ++P     
Sbjct: 644  RALGGDLAPVPSSPQP----------KLKTAPVTTTSAVSKSSPQP----QQTSPKKDAA 689

Query: 457  SQIDPSSIERAYAALGLPYQVNQMPT---QPQVQAKNQQNQQPGQSPQGMRPMSNMSASP 513
             + D S           P  + + PT    P  +AK     QP ++    +P      S 
Sbjct: 690  PKQDLSKAPEPKK----PPPLVKQPTLHGSPSAKAK-----QPPEADSLSKPAPPKEPS- 739

Query: 514  MGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHE 573
                       PS    + +      Q  M+     + S     T     ++ ++ Q  E
Sbjct: 740  ----------VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789

Query: 574  DITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLL 633
              T  L+     K  Q+  PT +  +  D +     A   K+      S+ ++ +     
Sbjct: 790  KTTPPLKTDSA-KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ----- 843

Query: 634  AEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSM 693
             +++  +QK+ E K+     K +  P+A  M   S  P      P P  T+   +P P  
Sbjct: 844  -KQVDPVQKKEEPKKAQT--KMSPKPDAKPMPKGSPTP------PGPRPTAGQTVPTP-- 892

Query: 694  IRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGA--LNPPMGY 751
                   Q  P+   QS        S+   P     TP     G+L   GA   +     
Sbjct: 893  -------QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945

Query: 752  GPRMQQP---SNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM 808
                 QP   S  G   P  Q P+     T+     S+GQAP + A+    S PV     
Sbjct: 946  ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK----SIPVKKETK 1001

Query: 809  PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPA 868
             P ++          +P   Q   +P   RT T    PP   ++   A    A +PT   
Sbjct: 1002 APAAEKL--------EPKAEQ---APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050

Query: 869  MPPGPQSQA------LHPPPRQTPTPPT-TQLPQQVQPSLPAAPSADQPQQQP----RSQ 917
              P P+S        L+   +  P   T T+   QV       P+    + Q       Q
Sbjct: 1051 KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110

Query: 918  QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVK 977
               A S        +PP P+ P + P       V    S+  T V  Q    K+  QEVK
Sbjct: 1111 TQRAISGQLGDIRKMPPAPSGPKASPM-----PVPTESSSQKTAVPPQVKLVKKQEQEVK 1165

Query: 978  MEAK----------MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEE 1027
             EA+          + +++  P  T  +   ESK+E  K  + + ++   E K  I EEE
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE 1225

Query: 1028 ----DQPSTSATQSSPAPGQSK----KKIFKPEELRQALM 1059
                ++      +  P P   K     K   PEE +  L+
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLL 1265



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 105/470 (22%), Positives = 164/470 (34%), Gaps = 77/470 (16%)

Query: 666  PVSMNPGPNMGQPQ-----------PGMTSNGPL-PDPSMIRGSVPNQMMPRITPQSGLN 713
            P    PGP    PQ           PG T   P  P P+      P    P         
Sbjct: 479  PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538

Query: 714  QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ 773
               Q      P   + T P+   G   +P  L PP    P  +QP +QG  LP+T  P  
Sbjct: 539  PSAQQPSPAKPSAQQSTKPVSQTGS-GKP--LQPPT-VSPSAKQPPSQG--LPKTICPLC 592

Query: 774  GMNVTNIPLAPSSGQAPVSQAQMSSSS-CPVN-SPIMPPGSQGSHIHC------------ 819
                  + +   +     ++ Q +  S C  N +P +    +   ++C            
Sbjct: 593  NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652

Query: 820  -PQLPQPALHQ---NSPSPVPSRTPTPHHTPPSIGA------QQPPATTIPAPVPTPPAM 869
             P  PQP L      + S V   +P P  T P   A       + P    P P+   P +
Sbjct: 653  VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712

Query: 870  PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA 929
               P ++A  PP   + + P       V      AP AD   +QP+  + T   V + +A
Sbjct: 713  HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772

Query: 930  PLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEP 989
               P  P++ +   A     + + PP  + +   SQ+     P    K+        P P
Sbjct: 773  TTKPDIPSSKVQSQA----EEKTTPPLKTDSAKPSQSF----PPTGEKVSPFDSKAIPRP 824

Query: 990  AD-----TQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQ------------PST 1032
            A      + P   SESK +  +++  + +E   + +T++  + D             P  
Sbjct: 825  ASDSKIISHPGPSSESKGQK-QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 1033 SATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ 1082
            +A Q+ P P QS     KP+E  +     L ++        P  QP  PQ
Sbjct: 884  TAGQTVPTPQQSP----KPQEQSRRFSLNLGSI-----TDAPKSQPTTPQ 924



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 93/389 (23%), Positives = 133/389 (34%), Gaps = 65/389 (16%)

Query: 743  GALNPPMGYGPRMQQPSNQG--------QFLPQTQFPSQGMNVTNIPLAPSSG---QAPV 791
            G + PP+   P    P  QG           P++    Q   + + P  P +G   Q P 
Sbjct: 205  GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPT 262

Query: 792  SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP------TPHHT 845
               Q   +  P+      P ++ + I   +  +P+L   S  P+   TP       P H 
Sbjct: 263  QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 846  PPSIGAQ------------------------QPPATTIPAPVPTPPAMPPGPQSQALHPP 881
                G                          QPP TT P   P  PA PP  Q+ +  P 
Sbjct: 323  KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 882  PRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA-TPL 940
              Q P P     P  V  +    P   +P  Q        A  P   +P   P P  TP+
Sbjct: 383  SEQ-PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 941  SQPAV-SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999
             QP    I  Q + P  TS     +Q     +P  ++   AK    QP PA   P+    
Sbjct: 442  QQPGPGKIPAQQAGPGKTS-----AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496

Query: 1000 SKVEDCKMESTETEER-------STELKTEIKEEEDQPST---SATQSSPA---PGQSKK 1046
            +K    +  ST+   +       S +     K    QP +   SA Q SPA     QS K
Sbjct: 497  AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 1047 KIFKPEELRQALMPTLEALYRQDP-ESLP 1074
             + +    +    PT+    +Q P + LP
Sbjct: 557  PVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 130/619 (21%), Positives = 193/619 (31%), Gaps = 162/619 (26%)

Query: 1850 PTPATPTT-------PTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            P PA P T       P  QQP   Q+P     P  TP     P     Q AGP   GK +
Sbjct: 405  PGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGP---GKTS 460

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTP- 1961
             Q T PT P +  P    PPP                         Q+P   + PP  P 
Sbjct: 461  AQQTGPTKPPSQLPGPAKPPP-------------------------QQPGPAKPPPQQPG 495

Query: 1962 ------MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAM 2015
                    P    PPP   GP+       G T    +PP  Q G  +P   Q   P PA 
Sbjct: 496  SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST----KPPSQQPGSAKPSAQQ---PSPAK 548

Query: 2016 MSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQ--------- 2066
             S  Q  +P++   Q G G+    PL+P TVS  A Q   + L     PL          
Sbjct: 549  PSAQQSTKPVS---QTGSGK----PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601

Query: 2067 ------------QQQVLSILHANPQLLAAFIKQ--------------------------- 2087
                        Q  V S+   NP      +K+                           
Sbjct: 602  PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661

Query: 2088 ------RAAKYANSNPQPIPGQP--------GMPQGQPGLQPPTMPGQQGVHSNPAMQNM 2133
                    +  + S+PQP    P         + +     +PP +  Q  +H +P+ +  
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721

Query: 2134 NPMQAGVQRAGLPQQQPQ---QQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQ---Q 2187
             P +A       P ++P    +Q + P+    P+  +M      + S      +      
Sbjct: 722  QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781

Query: 2188 MMQQQQQQGAGPGIGPGMANHNQFQQPQG----------VGYPPQQQQRMQHHMQQMQQG 2237
             +Q Q ++   P +    A  +Q   P G          +  P    + + H     +  
Sbjct: 782  KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841

Query: 2238 NMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQ 2297
               Q+  + +    +   +  + +        GSP  P P       +P   QSP  Q Q
Sbjct: 842  GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901

Query: 2298 ---------QIPNSLSNQVRSPQPVPSPR-----------------PQSQP-PHSSPSPR 2330
                      I ++  +Q  +PQ   + +                    QP PHS   P 
Sbjct: 902  SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961

Query: 2331 MQPQPSPHHVSPQTSSPHP 2349
               + +P    P TS   P
Sbjct: 962  APMKQAPAPSQPPTSQGPP 980



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 137/588 (23%), Positives = 203/588 (34%), Gaps = 110/588 (18%)

Query: 1840 VVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899
            VV ++QG P         P  QQP           P+P P    P   P  Q   P S  
Sbjct: 195  VVQKEQGKPE---GIIKPPLQQQP-----------PKPIPKQQGPGRDPLQQDGTPKSIS 240

Query: 1900 KAAGQVTPPTPPQTAQPPLPGP--PPAAVEMAMQIQR-AAETQRQMAHV----------- 1945
                +     PP T + P+ GP   P      + +QR A+  Q + A +           
Sbjct: 241  SQQPEKIKSQPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP 299

Query: 1946 QIFQRPIQHQMPPMTPMAPMG--------MNPP--------PMTRGPSGHLEPGMGPTGM 1989
               + PIQ   P   P    G          PP        P+ + P G ++P + P G 
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-GTVKPPVQPPG- 357

Query: 1990 QQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGI---SPLKPGT- 2045
              +PP    G  +P   Q+G  +P+    ++   P  +A  PG+G+       P KP T 
Sbjct: 358  TTKPPAQPLGPAKPPAQQTGSEKPS----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413

Query: 2046 --------VSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSN- 2096
                      Q  LQ+  +      +P+QQ     I    P   A   K  A +   +  
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI----PAQQAGPGKTSAQQTGPTKP 469

Query: 2097 PQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQ--QL 2154
            P  +PG    P  QPG  P   P QQ   + P  Q     +   Q+ G  +  PQQ    
Sbjct: 470  PSQLPGPAKPPPQQPG--PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527

Query: 2155 QPPM---GGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQF 2211
            +PP    G   P AQQ        PS  +     QQ  +   Q G+G  + P   + +  
Sbjct: 528  KPPSQQPGSAKPSAQQ--------PSPAKP--SAQQSTKPVSQTGSGKPLQPPTVSPSA- 576

Query: 2212 QQPQGVGYPPQ-----QQQRMQHHMQQMQQGNMGQIGQ--LPQALGAEAGASLQAYQQRL 2264
            +QP   G P           +  H+ +    N     Q  +    G      L   ++ L
Sbjct: 577  KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636

Query: 2265 -----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQ 2319
                 +++ +G  + P P SPQ          P L+   +  + +    SPQP  +   +
Sbjct: 637  CLNCQMKRALGGDLAPVPSSPQ----------PKLKTAPVTTTSAVSKSSPQPQQTSPKK 686

Query: 2320 SQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASP 2367
               P    S   +P+  P  V   T    P   A Q  P E    + P
Sbjct: 687  DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ--PPEADSLSKP 732



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 112/448 (25%), Positives = 150/448 (33%), Gaps = 114/448 (25%)

Query: 1976 PSGHLEPGMGPTGMQQQPPW----SQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQP 2031
            P G ++P +     QQQPP      QG    P Q Q G P+      +Q  + +   P P
Sbjct: 203  PEGIIKPPL-----QQQPPKPIPKQQGPGRDPLQ-QDGTPKSIS---SQQPEKIKSQP-P 252

Query: 2032 GLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAK 2091
            G G+    P++  T + Q     L   R  S P  +Q             A  ++  + K
Sbjct: 253  GTGK----PIQGPTQTPQTDHAKLPLQRDASRPQTKQ-------------ADIVRGESVK 295

Query: 2092 YANSNP------QPIPG-----QPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGV 2140
             +  +P      QP PG     QPG  + QPG  P   P Q    + P  Q    ++  V
Sbjct: 296  PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPPV 353

Query: 2141 QRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPG 2200
            Q  G  +   Q     P+G   P AQQ                      ++   +  GP 
Sbjct: 354  QPPGTTKPPAQ-----PLGPAKPPAQQTGS-------------------EKPSSEQPGP- 388

Query: 2201 IGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLP--QALGAEAGASLQ 2258
                        QP GVG  P QQ        Q Q G    + Q P  Q+     G +  
Sbjct: 389  --------KALAQPPGVGKTPAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAKAPGPTKT 439

Query: 2259 AYQQ----RLLQQQMG----SPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP 2310
              QQ    ++  QQ G    S  Q  P  P    LP  A+ P       P         P
Sbjct: 440  PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPP-------PQQPGPAKPPP 491

Query: 2311 QPVPSPRPQSQPPHSSPSPRMQPQPS----------------PHHVSPQTSSPHPGLVAA 2354
            Q   S +P SQ P S+  P  QP P+                P    P    P P   +A
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 2355 Q--ANPMEQGHFASPDQNSMLSQLASNP 2380
            Q    P+ Q     P Q   +S  A  P
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 79/356 (22%), Positives = 116/356 (32%), Gaps = 86/356 (24%)

Query: 762  GQFLPQTQFPSQGMNVTNIPLAPS----SGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            GQ  P +Q PS   +V+++P  P     S    +S         P   P  PP      +
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427

Query: 818  HCPQLPQPALHQNSP----SPVPSRTP-----TPHHTPPSIGAQQPPAT----TIPAPVP 864
              P  P+P +         SPV + TP     T   T   + +   P T    T P PVP
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487

Query: 865  TPPAMPPG---------PQSQALHPPPRQTPTPPTTQLPQQVQPS--------------- 900
              P+  P          P    + P P     P TTQ P  + P                
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547

Query: 901  ------LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPL-------------- 940
                  LP+  S   P     S + + +   T     LP +P TP               
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607

Query: 941  --SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDIS 998
              S+  VS+E   S  P  ++ E+   +      S  ++  +   V  P      P  ++
Sbjct: 2608 SPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVT 2667

Query: 999  ESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQS-SPAPGQSKKKIFKPEE 1053
            +                   L TE+ + E     SAT+S +P+ G S   I  P E
Sbjct: 2668 QF------------------LTTEVSKTE----VSATRSTAPSVGLSSISITIPPE 2701



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 51/213 (23%), Positives = 81/213 (38%), Gaps = 22/213 (10%)

Query: 852  QQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911
            +QP       P  TP ++P   +        ++ P PP T  P QV+P        D   
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPK--EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKS 1346

Query: 912  -----QQPRSQQ--------STAASVPTPTAPLLPPQPATP----LSQPAVSIEGQVSNP 954
                 QQP+S Q        S   S      P L P         L + + S E   S+P
Sbjct: 1347 DTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSP 1406

Query: 955  PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEE 1014
               +  E    +I E Q S     +++ +    E +  QP+D  +++     +E T +EE
Sbjct: 1407 SDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEE 1466

Query: 1015 RSTELKTEIKEEEDQPSTSATQSSPAPGQSKKK 1047
               E+K   +E +D     + Q  P+    K+K
Sbjct: 1467 ---EIKESQEERKDTFKKDSQQDIPSSKDHKEK 1496



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 27/229 (11%)

Query: 765  LPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQ 824
            L +T F     +V  +P+         +  +      P +   +P GS  S    P  P+
Sbjct: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQ--LPSGSP-SVSSLPAKPR 2391

Query: 825  PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQ 884
            P   ++S   + ++ P P   PP      PP    P P PT P     P+ +     P  
Sbjct: 2392 P-FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVT 2450

Query: 885  TPTP-------------------PTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
            T TP                   P T++     P +P  PS+  P     + +   +  P
Sbjct: 2451 TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS-IPSGLVFTHRPEPSKPP 2509

Query: 926  TPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAE-KQPS 973
                P++P  P T  +Q    I  + +    TSS  +N    A+ K PS
Sbjct: 2510 IAPKPVIPQLPTT--TQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPS 2556



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 108/534 (20%), Positives = 184/534 (34%), Gaps = 91/534 (17%)

Query: 640  IQKELEEKRRTRLQKQNML---PNAAGMVPVSMN----PGPNMGQPQPGMTSNGPLPD-- 690
            + K  E K+   L KQ  L   P+A    P   +    P P      P      P+ D  
Sbjct: 694  LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753

Query: 691  ---PSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNP 747
               P M++ +         T +  +      S A+     + TPPL+     A+P    P
Sbjct: 754  PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE----KTTPPLKTDS--AKPSQSFP 807

Query: 748  PMGY------GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMS---- 797
            P G          + +P++  + +      S+      +       +   +Q +MS    
Sbjct: 808  PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 798  SSSCPVNSPIMPPGSQ---GSHIHCPQL-PQP-------ALHQNSPSPVPSRTPT-PHHT 845
            +   P  SP  PPG +   G  +  PQ  P+P       +L+  S +  P   PT P  T
Sbjct: 868  AKPMPKGSPT-PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926

Query: 846  PP-------------------SIGAQQPPATTIP-APVPTPPAMPPGPQSQALHPPPRQT 885
                                 + G   P + + P AP+   PA    P SQ       Q 
Sbjct: 927  VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 886  PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAV 945
            P  P   +P + +   PAA   +   +Q  + + T      P  P+   +  T   Q AV
Sbjct: 987  PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP--PIKDSKSLTAEPQKAV 1044

Query: 946  SIEGQVSNPPSTSS-----TEVNSQAIAEKQPSQ-EVKMEAKMEVDQPEPADTQPEDISE 999
                   +P   S+     TE+N   I  K P       E K +V      +  P     
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELN---IGSKDPPNFNTCTECKNQVCNLCGFNPTPH---L 1098

Query: 1000 SKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059
            +++++    + +T+   +    +I++    PS       P P +S  +       + A+ 
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQ-------KTAVP 1151

Query: 1060 PTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQE 1113
            P ++ + +Q+ E     + V           + VK  + +  I   + T Q QE
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKV---------ILEKVKETLSMEKIPPMVTTDQKQE 1196



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 40/164 (24%), Positives = 56/164 (34%), Gaps = 45/164 (27%)

Query: 1847 LPSPTPATPTTPTGQQP-----------TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGP 1895
            LPS +P+  + P   +P             P  P P   P P PP   PP LP   +  P
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435

Query: 1896 VSQGK----AAGQVTPPTP------------------------PQTAQPPLPGPPPAAVE 1927
                K     A  VT  TP                          TA PP+P P P+++ 
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP-PKPSSIP 2494

Query: 1928 MAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPP 1971
              +      E  +      I  +P+  Q+ P T   P  ++P P
Sbjct: 2495 SGLVFTHRPEPSKP----PIAPKPVIPQL-PTTTQKPTDIHPKP 2533



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 64/310 (20%), Positives = 102/310 (32%), Gaps = 62/310 (20%)

Query: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPP 1908
            +P P++P       P T  +    S PQP   +      P+  AA      KA     P 
Sbjct: 651  APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS------PKKDAAPKQDLSKAPEPKKP- 703

Query: 1909 TPPQTAQPPLPGPPPAAVEM---AMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
             PP   QP L G P A  +    A  + + A  +      +  + P+    P    M   
Sbjct: 704  -PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 1966 GMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPL 2025
              +   +    S   +P +  + +Q Q   ++     P +  S  P  +           
Sbjct: 763  TTD---LVSSSSATTKPDIPSSKVQSQ---AEEKTTPPLKTDSAKPSQSF---------- 806

Query: 2026 NMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFI 2085
                 P  G+  +SP     + + A  + + +   PSS  + Q+ +  +           
Sbjct: 807  -----PPTGE-KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ---------- 850

Query: 2086 KQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGL 2145
            K+   K A +   P P    MP+G      PT PG              P     Q    
Sbjct: 851  KKEEPKKAQTKMSPKPDAKPMPKGS-----PTPPG--------------PRPTAGQTVPT 891

Query: 2146 PQQQPQQQLQ 2155
            PQQ P+ Q Q
Sbjct: 892  PQQSPKPQEQ 901



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 58/211 (27%), Positives = 79/211 (37%), Gaps = 30/211 (14%)

Query: 139 GTSGPNQGPTQS--TGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSI 196
           GT  P QGPTQ+  T     P+ + A    T               G+ + P+       
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQT--------KQADIVRGESVKPSL------ 298

Query: 197 GAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQ-TGLRGPQPLKMGMMNNP-NPYG 254
                +  +Q P PG   A     E  Q G  +   Q +GL  P   + G +  P  P G
Sbjct: 299 -PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 255 SPYTQNPGQQIG-ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA---PQV 310
           +  T+ P Q +G A     Q  ++   S    P A+   A P G      QQP    P  
Sbjct: 358 T--TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKTPAQQPGPAKPPT 412

Query: 311 QQPGLVTPVAQ--GMGSGAHTADPEKRKLIQ 339
           QQ G   P+AQ  G+ S A    P K  + Q
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 58/247 (23%), Positives = 83/247 (33%), Gaps = 46/247 (18%)

Query: 1838 TGVVGQQQGLPSPT-PATPTTPTGQQPTTPQTPQPTSQP-QPTPPNS--MPPY----LPR 1889
            T +V        P  P++      ++ TTP     +++P Q  PP    + P+    +PR
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 1890 TQA-------AGPVSQGKAAGQVTP------PTPPQTAQPPLP-------------GPPP 1923
              +        GP S+ K   QV P      P   QT   P P             GP P
Sbjct: 824  PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 1924 AAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPG 1983
             A +     Q++ + Q Q     +    I    P   P  P            +G L  G
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQPTTPQ--------ETVTGKLF-G 933

Query: 1984 MGPTGMQQQPPW-SQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLK 2042
             G +   Q     S  G P P   QSG   P   + A    P +  P    GQ   +P K
Sbjct: 934  FGASIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 2043 PGTVSQQ 2049
               V ++
Sbjct: 993  SIPVKKE 999



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 3/55 (5%)

Query: 1870 QPTSQ-PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPP 1923
            +P SQ P  +P  S  P  PR       S    + Q  PP PP    PP P PPP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRS--SSLDISAQPPPPPPPPPPPPPPPPPPP 2423



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 2301 NSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP 2337
            +SL    + P P P P P   PP   P P + P  SP
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 130/534 (24%), Positives = 189/534 (35%), Gaps = 112/534 (20%)

Query: 1847 LPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVT 1906
            LPSP+      PT  +P   Q     SQP P  P + P  L +  A  P       G V 
Sbjct: 298  LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-------GTVK 350

Query: 1907 PPT-PPQTAQPPL----PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTP 1961
            PP  PP T +PP     P  PPA        Q  +E            +P   Q  P   
Sbjct: 351  PPVQPPGTTKPPAQPLGPAKPPAQ-------QTGSE------------KPSSEQPGPKAL 391

Query: 1962 MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ----QPPWSQGGLPQPQQLQSGMPRPAMMS 2017
              P                 PG+G T  QQ    +PP  Q G P+P   Q G+  PA   
Sbjct: 392  AQP-----------------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434

Query: 2018 VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
                G       QPG G++      PG  S Q         + P       Q        
Sbjct: 435  ----GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 2078 PQLLAAFIKQRAAKYANSNP---QPIPGQPG----MPQGQPGLQPPTMPGQQGVHSNPAM 2130
            PQ      +  +AK  +  P   +P P QPG     PQ QPG   P  P QQ   + P+ 
Sbjct: 491  PQ------QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQ-QPGSTKP--PSQQPGSAKPSA 541

Query: 2131 QNMNPMQAGVQRAGLPQQQ--PQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQM 2188
            Q  +P +   Q++  P  Q    + LQPP   +SP A+Q       +P     +    ++
Sbjct: 542  QQPSPAKPSAQQSTKPVSQTGSGKPLQPPT--VSPSAKQ--PPSQGLPKTICPLCNTTEL 597

Query: 2189 MQQQQQQGAGPGIGPGMANHNQFQQPQGV-----GYPPQQQQRMQHHMQQMQQGNMGQIG 2243
            +             P  AN N   + Q       G+ P        H+ ++++  +    
Sbjct: 598  LLHV----------PEKANFNTCTECQTTVCSLCGFNPNP------HLTEVKEW-LCLNC 640

Query: 2244 QLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQ-QHMLPNQAQSPHLQGQQIPNS 2302
            Q+ +ALG +      + Q +L    + +    +  SPQ Q   P +  +P          
Sbjct: 641  QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK--------- 691

Query: 2303 LSNQVRSPQPVPSPRPQSQPP-HSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQ 2355
              +  ++P+P   P    QP  H SPS + +  P    +S       P + + Q
Sbjct: 692  -QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 116/470 (24%), Positives = 170/470 (36%), Gaps = 111/470 (23%)

Query: 719  SMAQPPI---VPRQTPPLQHHGQLAQPGALNPPMGYG----PRMQQPSNQGQFLPQTQFP 771
            S ++PPI    P + P  Q   + +QPG   PP        P  QQP   G   P  Q P
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP---GTVKPPVQPP 356

Query: 772  SQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPI-MPPG---------------SQGS 815
                     PL P+   A  + ++  SS  P    +  PPG               +Q  
Sbjct: 357  GTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415

Query: 816  HIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQ--------------PPATTIPA 861
                P   QP L   + +P P++TP     P  I AQQ               P + +P 
Sbjct: 416  GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475

Query: 862  PVPTPPAMP----PGPQSQALHPPPRQTP--TPPTTQLPQQVQPSLPAAPSADQPQQQPR 915
            P   PP  P    P PQ      PP Q P  T P  Q P   +PS     S   P QQP 
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535

Query: 916  SQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
            S + +A   P+P  P    Q   P+SQ      G+   PP+ S +       A++ PSQ 
Sbjct: 536  SAKPSAQQ-PSPAKP-SAQQSTKPVSQTG---SGKPLQPPTVSPS-------AKQPPSQG 583

Query: 976  VKM-------EAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELK-------- 1020
            +           ++ +  PE A+      +E +   C +         TE+K        
Sbjct: 584  LPKTICPLCNTTELLLHVPEKANF--NTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQ 641

Query: 1021 -----------------TEIKEEEDQPSTSATQSSPAPGQS--KKKIFKPEELRQA---- 1057
                              ++K      +++ ++SSP P Q+  KK     ++L +A    
Sbjct: 642  MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK 701

Query: 1058 ------LMPTL----EALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPM 1097
                    PTL     A  +Q PE+    +P  P+   +P   D  K+P+
Sbjct: 702  KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD--KAPV 749



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 222/1000 (22%), Positives = 335/1000 (33%), Gaps = 170/1000 (17%)

Query: 107  QAQQSSPGLGLINSMVKSPMTQAGLTSP-NMGMGTSGPN------QGPTQSTGMMNSPVN 159
            +A    PG+G      K+P  Q G   P    +GT  P       Q P ++ G   +PV 
Sbjct: 389  KALAQPPGVG------KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442

Query: 160  QPAMGMNTGMNAGMNPGMLAAGN-GQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNL 218
            QP  G      AG  PG  +A   G    P+Q+       G  +   Q P P        
Sbjct: 443  QPGPGKIPAQQAG--PGKTSAQQTGPTKPPSQL------PGPAKPPPQQPGPAK------ 488

Query: 219  LTEPLQQGSPQMGGQT-GLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTK 277
               P Q GS +   Q  G   P P + G    P+P     T+ P QQ G++    Q  + 
Sbjct: 489  -PPPQQPGSAKPPSQQPGSTKPPPQQPGPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSP 546

Query: 278  TVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGSGAHTADPEKRKL 337
               S   S   + +    G G P      +P  +QP      +QG+        P+    
Sbjct: 547  AKPSAQQSTKPVSQT---GSGKPLQPPTVSPSAKQPP-----SQGL--------PKTICP 590

Query: 338  IQQQLVLLLHAHKCQRREQAN-GEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASS 396
            +     LLLH       E+AN     +C    C       N   H    K     +C   
Sbjct: 591  LCNTTELLLHVP-----EKANFNTCTECQTTVCSLCG--FNPNPHLTEVKEWLCLNCQMK 643

Query: 397  RQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQQSAPNLSTV 456
            R +            P          K    P+ T + V   +P      QQ++P     
Sbjct: 644  RALGGDLAPVPSSPQP----------KLKTAPVTTTSAVSKSSPQP----QQTSPKKDAA 689

Query: 457  SQIDPSSIERAYAALGLPYQVNQMPT---QPQVQAKNQQNQQPGQSPQGMRPMSNMSASP 513
             + D S           P  + + PT    P  +AK     QP ++    +P      S 
Sbjct: 690  PKQDLSKAPEPKK----PPPLVKQPTLHGSPSAKAK-----QPPEADSLSKPAPPKEPS- 739

Query: 514  MGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHE 573
                       PS    + +      Q  M+     + S     T     ++ ++ Q  E
Sbjct: 740  ----------VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789

Query: 574  DITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLL 633
              T  L+     K  Q+  PT +  +  D +     A   K+      S+ ++ +     
Sbjct: 790  KTTPPLKTDSA-KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ----- 843

Query: 634  AEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSM 693
             +++  +QK+ E K+     K +  P+A  M   S  P      P P  T+   +P P  
Sbjct: 844  -KQVDPVQKKEEPKKAQT--KMSPKPDAKPMPKGSPTP------PGPRPTAGQTVPTP-- 892

Query: 694  IRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGA--LNPPMGY 751
                   Q  P+   QS        S+   P     TP     G+L   GA   +     
Sbjct: 893  -------QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945

Query: 752  GPRMQQP---SNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM 808
                 QP   S  G   P  Q P+     T+     S+GQAP + A+    S PV     
Sbjct: 946  ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK----SIPVKKETK 1001

Query: 809  PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPA 868
             P ++          +P   Q   +P   RT T    PP   ++   A    A +PT   
Sbjct: 1002 APAAEKL--------EPKAEQ---APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050

Query: 869  MPPGPQSQA------LHPPPRQTPTPPT-TQLPQQVQPSLPAAPSADQPQQQP----RSQ 917
              P P+S        L+   +  P   T T+   QV       P+    + Q       Q
Sbjct: 1051 KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110

Query: 918  QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVK 977
               A S        +PP P+ P + P       V    S+  T V  Q    K+  QEVK
Sbjct: 1111 TQRAISGQLGDIRKMPPAPSGPKASPM-----PVPTESSSQKTAVPPQVKLVKKQEQEVK 1165

Query: 978  MEAK----------MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEE 1027
             EA+          + +++  P  T  +   ESK+E  K  + + ++   E K  I EEE
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE 1225

Query: 1028 ----DQPSTSATQSSPAPGQSK----KKIFKPEELRQALM 1059
                ++      +  P P   K     K   PEE +  L+
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLL 1265



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 105/470 (22%), Positives = 164/470 (34%), Gaps = 77/470 (16%)

Query: 666  PVSMNPGPNMGQPQ-----------PGMTSNGPL-PDPSMIRGSVPNQMMPRITPQSGLN 713
            P    PGP    PQ           PG T   P  P P+      P    P         
Sbjct: 479  PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538

Query: 714  QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQ 773
               Q      P   + T P+   G   +P  L PP    P  +QP +QG  LP+T  P  
Sbjct: 539  PSAQQPSPAKPSAQQSTKPVSQTGS-GKP--LQPPT-VSPSAKQPPSQG--LPKTICPLC 592

Query: 774  GMNVTNIPLAPSSGQAPVSQAQMSSSS-CPVN-SPIMPPGSQGSHIHC------------ 819
                  + +   +     ++ Q +  S C  N +P +    +   ++C            
Sbjct: 593  NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652

Query: 820  -PQLPQPALHQ---NSPSPVPSRTPTPHHTPPSIGA------QQPPATTIPAPVPTPPAM 869
             P  PQP L      + S V   +P P  T P   A       + P    P P+   P +
Sbjct: 653  VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712

Query: 870  PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA 929
               P ++A  PP   + + P       V      AP AD   +QP+  + T   V + +A
Sbjct: 713  HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA 772

Query: 930  PLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEP 989
               P  P++ +   A     + + PP  + +   SQ+     P    K+        P P
Sbjct: 773  TTKPDIPSSKVQSQA----EEKTTPPLKTDSAKPSQSF----PPTGEKVSPFDSKAIPRP 824

Query: 990  AD-----TQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQ------------PST 1032
            A      + P   SESK +  +++  + +E   + +T++  + D             P  
Sbjct: 825  ASDSKIISHPGPSSESKGQK-QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 1033 SATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ 1082
            +A Q+ P P QS     KP+E  +     L ++        P  QP  PQ
Sbjct: 884  TAGQTVPTPQQSP----KPQEQSRRFSLNLGSI-----TDAPKSQPTTPQ 924



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 93/389 (23%), Positives = 133/389 (34%), Gaps = 65/389 (16%)

Query: 743  GALNPPMGYGPRMQQPSNQG--------QFLPQTQFPSQGMNVTNIPLAPSSG---QAPV 791
            G + PP+   P    P  QG           P++    Q   + + P  P +G   Q P 
Sbjct: 205  GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP--PGTGKPIQGPT 262

Query: 792  SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP------TPHHT 845
               Q   +  P+      P ++ + I   +  +P+L   S  P+   TP       P H 
Sbjct: 263  QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 846  PPSIGAQ------------------------QPPATTIPAPVPTPPAMPPGPQSQALHPP 881
                G                          QPP TT P   P  PA PP  Q+ +  P 
Sbjct: 323  KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382

Query: 882  PRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA-TPL 940
              Q P P     P  V  +    P   +P  Q        A  P   +P   P P  TP+
Sbjct: 383  SEQ-PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 941  SQPAV-SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999
             QP    I  Q + P  TS     +Q     +P  ++   AK    QP PA   P+    
Sbjct: 442  QQPGPGKIPAQQAGPGKTS-----AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496

Query: 1000 SKVEDCKMESTETEER-------STELKTEIKEEEDQPST---SATQSSPA---PGQSKK 1046
            +K    +  ST+   +       S +     K    QP +   SA Q SPA     QS K
Sbjct: 497  AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK 556

Query: 1047 KIFKPEELRQALMPTLEALYRQDP-ESLP 1074
             + +    +    PT+    +Q P + LP
Sbjct: 557  PVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 130/619 (21%), Positives = 193/619 (31%), Gaps = 162/619 (26%)

Query: 1850 PTPATPTT-------PTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            P PA P T       P  QQP   Q+P     P  TP     P     Q AGP   GK +
Sbjct: 405  PGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGP---GKTS 460

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTP- 1961
             Q T PT P +  P    PPP                         Q+P   + PP  P 
Sbjct: 461  AQQTGPTKPPSQLPGPAKPPP-------------------------QQPGPAKPPPQQPG 495

Query: 1962 ------MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAM 2015
                    P    PPP   GP+       G T    +PP  Q G  +P   Q   P PA 
Sbjct: 496  SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST----KPPSQQPGSAKPSAQQ---PSPAK 548

Query: 2016 MSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQ--------- 2066
             S  Q  +P++   Q G G+    PL+P TVS  A Q   + L     PL          
Sbjct: 549  PSAQQSTKPVS---QTGSGK----PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601

Query: 2067 ------------QQQVLSILHANPQLLAAFIKQ--------------------------- 2087
                        Q  V S+   NP      +K+                           
Sbjct: 602  PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661

Query: 2088 ------RAAKYANSNPQPIPGQP--------GMPQGQPGLQPPTMPGQQGVHSNPAMQNM 2133
                    +  + S+PQP    P         + +     +PP +  Q  +H +P+ +  
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721

Query: 2134 NPMQAGVQRAGLPQQQPQ---QQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQ---Q 2187
             P +A       P ++P    +Q + P+    P+  +M      + S      +      
Sbjct: 722  QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781

Query: 2188 MMQQQQQQGAGPGIGPGMANHNQFQQPQG----------VGYPPQQQQRMQHHMQQMQQG 2237
             +Q Q ++   P +    A  +Q   P G          +  P    + + H     +  
Sbjct: 782  KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841

Query: 2238 NMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQ 2297
               Q+  + +    +   +  + +        GSP  P P       +P   QSP  Q Q
Sbjct: 842  GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901

Query: 2298 ---------QIPNSLSNQVRSPQPVPSPR-----------------PQSQP-PHSSPSPR 2330
                      I ++  +Q  +PQ   + +                    QP PHS   P 
Sbjct: 902  SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961

Query: 2331 MQPQPSPHHVSPQTSSPHP 2349
               + +P    P TS   P
Sbjct: 962  APMKQAPAPSQPPTSQGPP 980



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 137/588 (23%), Positives = 203/588 (34%), Gaps = 110/588 (18%)

Query: 1840 VVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899
            VV ++QG P         P  QQP           P+P P    P   P  Q   P S  
Sbjct: 195  VVQKEQGKPE---GIIKPPLQQQP-----------PKPIPKQQGPGRDPLQQDGTPKSIS 240

Query: 1900 KAAGQVTPPTPPQTAQPPLPGP--PPAAVEMAMQIQR-AAETQRQMAHV----------- 1945
                +     PP T + P+ GP   P      + +QR A+  Q + A +           
Sbjct: 241  SQQPEKIKSQPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP 299

Query: 1946 QIFQRPIQHQMPPMTPMAPMG--------MNPP--------PMTRGPSGHLEPGMGPTGM 1989
               + PIQ   P   P    G          PP        P+ + P G ++P + P G 
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-GTVKPPVQPPG- 357

Query: 1990 QQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGI---SPLKPGT- 2045
              +PP    G  +P   Q+G  +P+    ++   P  +A  PG+G+       P KP T 
Sbjct: 358  TTKPPAQPLGPAKPPAQQTGSEKPS----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413

Query: 2046 --------VSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSN- 2096
                      Q  LQ+  +      +P+QQ     I    P   A   K  A +   +  
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI----PAQQAGPGKTSAQQTGPTKP 469

Query: 2097 PQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQ--QL 2154
            P  +PG    P  QPG  P   P QQ   + P  Q     +   Q+ G  +  PQQ    
Sbjct: 470  PSQLPGPAKPPPQQPG--PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527

Query: 2155 QPPM---GGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQF 2211
            +PP    G   P AQQ        PS  +     QQ  +   Q G+G  + P   + +  
Sbjct: 528  KPPSQQPGSAKPSAQQ--------PSPAKP--SAQQSTKPVSQTGSGKPLQPPTVSPSA- 576

Query: 2212 QQPQGVGYPPQ-----QQQRMQHHMQQMQQGNMGQIGQ--LPQALGAEAGASLQAYQQRL 2264
            +QP   G P           +  H+ +    N     Q  +    G      L   ++ L
Sbjct: 577  KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636

Query: 2265 -----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQ 2319
                 +++ +G  + P P SPQ          P L+   +  + +    SPQP  +   +
Sbjct: 637  CLNCQMKRALGGDLAPVPSSPQ----------PKLKTAPVTTTSAVSKSSPQPQQTSPKK 686

Query: 2320 SQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASP 2367
               P    S   +P+  P  V   T    P   A Q  P E    + P
Sbjct: 687  DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ--PPEADSLSKP 732



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 112/448 (25%), Positives = 150/448 (33%), Gaps = 114/448 (25%)

Query: 1976 PSGHLEPGMGPTGMQQQPPW----SQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQP 2031
            P G ++P +     QQQPP      QG    P Q Q G P+      +Q  + +   P P
Sbjct: 203  PEGIIKPPL-----QQQPPKPIPKQQGPGRDPLQ-QDGTPKSIS---SQQPEKIKSQP-P 252

Query: 2032 GLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAK 2091
            G G+    P++  T + Q     L   R  S P  +Q             A  ++  + K
Sbjct: 253  GTGK----PIQGPTQTPQTDHAKLPLQRDASRPQTKQ-------------ADIVRGESVK 295

Query: 2092 YANSNP------QPIPG-----QPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGV 2140
             +  +P      QP PG     QPG  + QPG  P   P Q    + P  Q    ++  V
Sbjct: 296  PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPPV 353

Query: 2141 QRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPG 2200
            Q  G  +   Q     P+G   P AQQ                      ++   +  GP 
Sbjct: 354  QPPGTTKPPAQ-----PLGPAKPPAQQTGS-------------------EKPSSEQPGP- 388

Query: 2201 IGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLP--QALGAEAGASLQ 2258
                        QP GVG  P QQ        Q Q G    + Q P  Q+     G +  
Sbjct: 389  --------KALAQPPGVGKTPAQQPGPAKPPTQ-QVGTPKPLAQQPGLQSPAKAPGPTKT 439

Query: 2259 AYQQ----RLLQQQMG----SPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP 2310
              QQ    ++  QQ G    S  Q  P  P    LP  A+ P       P         P
Sbjct: 440  PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPP-------PQQPGPAKPPP 491

Query: 2311 QPVPSPRPQSQPPHSSPSPRMQPQPS----------------PHHVSPQTSSPHPGLVAA 2354
            Q   S +P SQ P S+  P  QP P+                P    P    P P   +A
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 2355 Q--ANPMEQGHFASPDQNSMLSQLASNP 2380
            Q    P+ Q     P Q   +S  A  P
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 79/356 (22%), Positives = 116/356 (32%), Gaps = 86/356 (24%)

Query: 762  GQFLPQTQFPSQGMNVTNIPLAPS----SGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            GQ  P +Q PS   +V+++P  P     S    +S         P   P  PP      +
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427

Query: 818  HCPQLPQPALHQNSP----SPVPSRTP-----TPHHTPPSIGAQQPPAT----TIPAPVP 864
              P  P+P +         SPV + TP     T   T   + +   P T    T P PVP
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487

Query: 865  TPPAMPPG---------PQSQALHPPPRQTPTPPTTQLPQQVQPS--------------- 900
              P+  P          P    + P P     P TTQ P  + P                
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547

Query: 901  ------LPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPL-------------- 940
                  LP+  S   P     S + + +   T     LP +P TP               
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG 2607

Query: 941  --SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDIS 998
              S+  VS+E   S  P  ++ E+   +      S  ++  +   V  P      P  ++
Sbjct: 2608 SPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVT 2667

Query: 999  ESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQS-SPAPGQSKKKIFKPEE 1053
            +                   L TE+ + E     SAT+S +P+ G S   I  P E
Sbjct: 2668 QF------------------LTTEVSKTE----VSATRSTAPSVGLSSISITIPPE 2701



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 51/213 (23%), Positives = 81/213 (38%), Gaps = 22/213 (10%)

Query: 852  QQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQ 911
            +QP       P  TP ++P   +        ++ P PP T  P QV+P        D   
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPK--EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKS 1346

Query: 912  -----QQPRSQQ--------STAASVPTPTAPLLPPQPATP----LSQPAVSIEGQVSNP 954
                 QQP+S Q        S   S      P L P         L + + S E   S+P
Sbjct: 1347 DTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSP 1406

Query: 955  PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEE 1014
               +  E    +I E Q S     +++ +    E +  QP+D  +++     +E T +EE
Sbjct: 1407 SDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEE 1466

Query: 1015 RSTELKTEIKEEEDQPSTSATQSSPAPGQSKKK 1047
               E+K   +E +D     + Q  P+    K+K
Sbjct: 1467 ---EIKESQEERKDTFKKDSQQDIPSSKDHKEK 1496



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 27/229 (11%)

Query: 765  LPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQ 824
            L +T F     +V  +P+         +  +      P +   +P GS  S    P  P+
Sbjct: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQ--LPSGSP-SVSSLPAKPR 2391

Query: 825  PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQ 884
            P   ++S   + ++ P P   PP      PP    P P PT P     P+ +     P  
Sbjct: 2392 P-FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVT 2450

Query: 885  TPTP-------------------PTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
            T TP                   P T++     P +P  PS+  P     + +   +  P
Sbjct: 2451 TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS-IPSGLVFTHRPEPSKPP 2509

Query: 926  TPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAE-KQPS 973
                P++P  P T  +Q    I  + +    TSS  +N    A+ K PS
Sbjct: 2510 IAPKPVIPQLPTT--TQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPS 2556



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 108/534 (20%), Positives = 184/534 (34%), Gaps = 91/534 (17%)

Query: 640  IQKELEEKRRTRLQKQNML---PNAAGMVPVSMN----PGPNMGQPQPGMTSNGPLPD-- 690
            + K  E K+   L KQ  L   P+A    P   +    P P      P      P+ D  
Sbjct: 694  LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753

Query: 691  ---PSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNP 747
               P M++ +         T +  +      S A+     + TPPL+     A+P    P
Sbjct: 754  PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE----KTTPPLKTDS--AKPSQSFP 807

Query: 748  PMGY------GPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMS---- 797
            P G          + +P++  + +      S+      +       +   +Q +MS    
Sbjct: 808  PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 798  SSSCPVNSPIMPPGSQ---GSHIHCPQL-PQP-------ALHQNSPSPVPSRTPT-PHHT 845
            +   P  SP  PPG +   G  +  PQ  P+P       +L+  S +  P   PT P  T
Sbjct: 868  AKPMPKGSPT-PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQET 926

Query: 846  PP-------------------SIGAQQPPATTIP-APVPTPPAMPPGPQSQALHPPPRQT 885
                                 + G   P + + P AP+   PA    P SQ       Q 
Sbjct: 927  VTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 886  PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAV 945
            P  P   +P + +   PAA   +   +Q  + + T      P  P+   +  T   Q AV
Sbjct: 987  PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP--PIKDSKSLTAEPQKAV 1044

Query: 946  SIEGQVSNPPSTSS-----TEVNSQAIAEKQPSQ-EVKMEAKMEVDQPEPADTQPEDISE 999
                   +P   S+     TE+N   I  K P       E K +V      +  P     
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELN---IGSKDPPNFNTCTECKNQVCNLCGFNPTPH---L 1098

Query: 1000 SKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALM 1059
            +++++    + +T+   +    +I++    PS       P P +S  +       + A+ 
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQ-------KTAVP 1151

Query: 1060 PTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQE 1113
            P ++ + +Q+ E     + V           + VK  + +  I   + T Q QE
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKV---------ILEKVKETLSMEKIPPMVTTDQKQE 1196



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 40/164 (24%), Positives = 56/164 (34%), Gaps = 45/164 (27%)

Query: 1847 LPSPTPATPTTPTGQQP-----------TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGP 1895
            LPS +P+  + P   +P             P  P P   P P PP   PP LP   +  P
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435

Query: 1896 VSQGK----AAGQVTPPTP------------------------PQTAQPPLPGPPPAAVE 1927
                K     A  VT  TP                          TA PP+P P P+++ 
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP-PKPSSIP 2494

Query: 1928 MAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPP 1971
              +      E  +      I  +P+  Q+ P T   P  ++P P
Sbjct: 2495 SGLVFTHRPEPSKP----PIAPKPVIPQL-PTTTQKPTDIHPKP 2533



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 64/310 (20%), Positives = 102/310 (32%), Gaps = 62/310 (20%)

Query: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPP 1908
            +P P++P       P T  +    S PQP   +      P+  AA      KA     P 
Sbjct: 651  APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS------PKKDAAPKQDLSKAPEPKKP- 703

Query: 1909 TPPQTAQPPLPGPPPAAVEM---AMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
             PP   QP L G P A  +    A  + + A  +      +  + P+    P    M   
Sbjct: 704  -PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 1966 GMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPL 2025
              +   +    S   +P +  + +Q Q   ++     P +  S  P  +           
Sbjct: 763  TTD---LVSSSSATTKPDIPSSKVQSQ---AEEKTTPPLKTDSAKPSQSF---------- 806

Query: 2026 NMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFI 2085
                 P  G+  +SP     + + A  + + +   PSS  + Q+ +  +           
Sbjct: 807  -----PPTGE-KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ---------- 850

Query: 2086 KQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGL 2145
            K+   K A +   P P    MP+G      PT PG              P     Q    
Sbjct: 851  KKEEPKKAQTKMSPKPDAKPMPKGS-----PTPPG--------------PRPTAGQTVPT 891

Query: 2146 PQQQPQQQLQ 2155
            PQQ P+ Q Q
Sbjct: 892  PQQSPKPQEQ 901



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 58/211 (27%), Positives = 79/211 (37%), Gaps = 30/211 (14%)

Query: 139 GTSGPNQGPTQS--TGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSI 196
           GT  P QGPTQ+  T     P+ + A    T               G+ + P+       
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQT--------KQADIVRGESVKPSL------ 298

Query: 197 GAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQ-TGLRGPQPLKMGMMNNP-NPYG 254
                +  +Q P PG   A     E  Q G  +   Q +GL  P   + G +  P  P G
Sbjct: 299 -PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 255 SPYTQNPGQQIG-ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA---PQV 310
           +  T+ P Q +G A     Q  ++   S    P A+   A P G      QQP    P  
Sbjct: 358 T--TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKTPAQQPGPAKPPT 412

Query: 311 QQPGLVTPVAQ--GMGSGAHTADPEKRKLIQ 339
           QQ G   P+AQ  G+ S A    P K  + Q
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ 443



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 58/247 (23%), Positives = 83/247 (33%), Gaps = 46/247 (18%)

Query: 1838 TGVVGQQQGLPSPT-PATPTTPTGQQPTTPQTPQPTSQP-QPTPPNS--MPPY----LPR 1889
            T +V        P  P++      ++ TTP     +++P Q  PP    + P+    +PR
Sbjct: 764  TDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823

Query: 1890 TQA-------AGPVSQGKAAGQVTP------PTPPQTAQPPLP-------------GPPP 1923
              +        GP S+ K   QV P      P   QT   P P             GP P
Sbjct: 824  PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883

Query: 1924 AAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPG 1983
             A +     Q++ + Q Q     +    I    P   P  P            +G L  G
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQPTTPQ--------ETVTGKLF-G 933

Query: 1984 MGPTGMQQQPPW-SQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLK 2042
             G +   Q     S  G P P   QSG   P   + A    P +  P    GQ   +P K
Sbjct: 934  FGASIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 2043 PGTVSQQ 2049
               V ++
Sbjct: 993  SIPVKKE 999



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 21/55 (38%), Positives = 24/55 (43%), Gaps = 3/55 (5%)

Query: 1870 QPTSQ-PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPP 1923
            +P SQ P  +P  S  P  PR       S    + Q  PP PP    PP P PPP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRS--SSLDISAQPPPPPPPPPPPPPPPPPPP 2423



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 2301 NSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP 2337
            +SL    + P P P P P   PP   P P + P  SP
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 127/470 (27%), Positives = 164/470 (34%), Gaps = 90/470 (19%)

Query: 1855 PTTPTGQQPTTPQTPQPTSQ----PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTP 1910
            P  P  ++P  P   +P  +    P+   P + PP     +     ++GK   Q    T 
Sbjct: 1743 PLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKS--TKGKKRSQPATKTE 1800

Query: 1911 PQTAQPPLPGP-----PPAAVEMAMQIQRAAETQRQMAHVQIFQ-RPIQHQMPPMTPMAP 1964
                 P   GP     PP  +             RQ +     Q +P+    P + P  P
Sbjct: 1801 DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP 1860

Query: 1965 MGMNPPPMTRGPSGHLEPGMGPTGM-----------------QQQPPWSQGGLPQPQQLQ 2007
            + +   PM + P+    PG+ PT M                 QQQP   QG   + QQLQ
Sbjct: 1861 VRL---PMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLR-QQLQ 1916

Query: 2008 SGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQ 2067
                     SV Q      M P    G        P  VS   LQ       +   P   
Sbjct: 1917 QSQGMLGQSSVHQ------MTPSSSYGLQTSQGYTP-YVSHVGLQQHTGPAGTMVPPSYS 1969

Query: 2068 QQVLSILH--ANPQLL--AAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQG 2123
             Q     H   NP L+     ++QR + Y +            P    GL        Q 
Sbjct: 1970 SQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQA---------PTYGHGLTSTQRFSHQT 2020

Query: 2124 VHSNPAMQNMNPM-----QAGVQRAGL---PQQQPQQQLQPPMGGMSPQAQQMNMNHNTM 2175
            +   P +  M PM     QAGV+   +    QQQ QQQ Q        Q QQ    ++  
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080

Query: 2176 PSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQ 2235
              Q + ILR+QQ  QQQQQQ              Q QQ Q      QQQQ+ QH  QQ Q
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQ------------QQQQQQQQ------QQQQQQQHQQQQQQ 2122

Query: 2236 QGNMGQIGQLPQALGAEAGASLQAYQQ--------RLLQQQMGSPVQPNP 2277
            Q    Q    PQ+        LQ  QQ        R LQQQ+ S  QP P
Sbjct: 2123 QAAPPQ--PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL-SNTQPQP 2169



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 94/453 (20%), Positives = 145/453 (32%), Gaps = 70/453 (15%)

Query: 1926 VEMAMQIQRAAETQRQMA-HVQIFQRPIQHQMPPMT-------PMAPMGMNPPPMTRGPS 1977
            V +  ++ R  E QR +  H  +  RP  + + P+        P AP  + P      P 
Sbjct: 1708 VRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPP 1767

Query: 1978 GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVG 2037
               +PG  P   +++   S  G                    +  QP       G+G   
Sbjct: 1768 KTDKPGAAPPSTEERKKKSTKG-------------------KKRSQPATKTEDYGMG--- 1805

Query: 2038 ISPLKPGTVSQQALQNLLRTLRSPSSPLQ---QQQVLSILHANPQLLAAFIKQRAAKYAN 2094
              P + G        +LL    +P S      +Q  + +   N  L A   +    +   
Sbjct: 1806 --PGRSGPYGVTVPPDLLHH-PNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVR 1862

Query: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL 2154
               Q +P +P  P    G+ P TM G  G+  +    ++   Q      G   +Q  QQ 
Sbjct: 1863 LPMQKLPTRPTYP----GVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQS 1918

Query: 2155 QPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQ---------------QQQQGAGP 2199
            Q  +G  S      + ++    SQ          +QQ               Q  Q   P
Sbjct: 1919 QGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHP 1978

Query: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQ--------ALGA 2251
               P + +  +  Q +  GY  QQ     H +   Q+ +   + Q P         A G 
Sbjct: 1979 STNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGV 2038

Query: 2252 EAGA-------SLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLS 2304
            +AG          Q  QQ+  QQQ     Q      QQ+ +  Q Q   L+ QQ      
Sbjct: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098

Query: 2305 NQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP 2337
             Q +  Q     + Q Q           PQP P
Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131



 Score = 37.0 bits (84), Expect = 0.24
 Identities = 59/260 (22%), Positives = 94/260 (36%), Gaps = 14/260 (5%)

Query: 810  PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAM 869
            PGS  +H++  Q       QN P P       P+        + P   T P  +PT    
Sbjct: 1826 PGSI-THLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTG 1884

Query: 870  PPG--PQSQALHPPPRQTPTPPTTQ-LPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP- 925
              G  P S       +Q P  P  Q L QQ+Q S      +   Q  P S      S   
Sbjct: 1885 VMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGY 1944

Query: 926  TPTAPLLPPQ----PATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981
            TP    +  Q    PA  +  P+ S +   S  PST+ T V+     +++PS  V  +A 
Sbjct: 1945 TPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAP 2004

Query: 982  -----MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQ 1036
                 +   Q     T  +    S +     +  +   RST +  E ++++ Q      Q
Sbjct: 2005 TYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ 2064

Query: 1037 SSPAPGQSKKKIFKPEELRQ 1056
                  Q +++ +   + +Q
Sbjct: 2065 QQQQQQQQQQQQYHIRQQQQ 2084



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 80/348 (22%), Positives = 113/348 (32%), Gaps = 56/348 (16%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP 1907
            P   P T T   G +P++ +T     Q QP  P          Q+ G + Q  +  Q+TP
Sbjct: 1875 PGVLPTTMTGVMGLEPSSYKT-SVYRQQQPAVPQGQRLRQQLQQSQGMLGQS-SVHQMTP 1932

Query: 1908 PTPP--QTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQMPPMTPMA 1963
             +    QT+Q   P                      ++HV + Q   P    +PP     
Sbjct: 1933 SSSYGLQTSQGYTP---------------------YVSHVGLQQHTGPAGTMVPPSYSSQ 1971

Query: 1964 PMGMNPP---PMTRGPSGHLEPGMGPTG-MQQQPPWSQGGLPQPQQLQ-SGMPRPAMMSV 2018
            P     P   P    P+ HL+    P+G + QQ P    GL   Q+     + +  M+S 
Sbjct: 1972 PYQSTHPSTNPTLVDPTRHLQ--QRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIST 2029

Query: 2019 AQHGQPLN-MAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
                 P++    Q G+    I P       QQ  Q   +  +      QQQQ     H  
Sbjct: 2030 MT---PMSAQGVQAGVRSTAILP------EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080

Query: 2078 PQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQ 2137
             Q     ++Q+              Q    Q Q   Q      QQ  H     Q   P Q
Sbjct: 2081 QQQQQQILRQQQQ------------QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128

Query: 2138 AGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRR 2185
               Q     Q+Q  QQ Q      +   Q      NT P    +I  R
Sbjct: 2129 PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGR 2176



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 1810 KQKLRQQQLQHRLQQAQMLRRR------MASMQRTGVVGQQQGLPSPTPATPTTPTGQQP 1863
            +Q+ +QQQ Q + QQ Q  +++      +   Q+  ++ QQQ               QQ 
Sbjct: 2051 QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQ 2110

Query: 1864 TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
               Q  Q   Q Q  PP   P   P+ Q  G
Sbjct: 2111 QQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 26/86 (30%)

Query: 1791 YHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSP 1850
            YH +  Q+ +        ++Q+ +QQQ Q + QQ Q  +++    Q      QQQ     
Sbjct: 2077 YHIRQQQQQQI-------LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ----QQQ----- 2120

Query: 1851 TPATPTTPTGQQPTTPQTPQPTSQPQ 1876
                      QQ   P  PQP SQPQ
Sbjct: 2121 ----------QQQAAPPQPQPQSQPQ 2136



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 73/330 (22%), Positives = 106/330 (32%), Gaps = 43/330 (13%)

Query: 649  RTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPR--- 705
            R  +QK    P   G++P +M     + +P    TS      P++ +G    Q + +   
Sbjct: 1862 RLPMQKLPTRPTYPGVLPTTMTGVMGL-EPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQG 1920

Query: 706  ITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG--QLAQPGALNPPMGYGPRMQQ---PSN 760
            +  QS ++Q    S          TP + H G  Q   P     P  Y  +  Q   PS 
Sbjct: 1921 MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPST 1980

Query: 761  QGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS----------QAQMSSSSCPVNSPIMPP 810
                +  T+   Q  +      AP+ G    S          Q  M S+  P+++  +  
Sbjct: 1981 NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA 2040

Query: 811  GSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMP 870
            G + + I   Q  Q    Q        +          I  QQ                 
Sbjct: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQIL---------RQQ 2091

Query: 871  PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQP----------RSQQST 920
               Q Q      +Q       Q   Q Q    AAP   QPQ QP          + QQ T
Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151

Query: 921  AASVPTPTAPLLPPQPATPLSQPAVSIEGQ 950
            AA V      L   QP     QP+ +I G+
Sbjct: 2152 AALVRQLQQQLSNTQP-----QPSTNIFGR 2176


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 97/320 (30%), Positives = 120/320 (37%), Gaps = 74/320 (23%)

Query: 2102 GQPGMPQGQPGLQPPTMPGQQGV--HSNPAMQNMNPM-QAGVQRAGLPQQQPQQQLQPPM 2158
            G  G P    G QPP  PG  G+  HS   +    P  Q  +Q+  L QQQ QQQ Q   
Sbjct: 117  GAMGQPMSLSG-QPP--PGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQ 173

Query: 2159 GG------MSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQ 2212
                       Q QQ     + M  QF+ ++++QQ +QQQQQQ     I     N  Q Q
Sbjct: 174  QAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL-IKLHHQNQQQIQ 232

Query: 2213 QPQGVGYPPQQQQRM-QHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQ------RLL 2265
            Q Q      QQ QR+ Q  +QQ QQ    Q  Q  QAL A+        QQ      + L
Sbjct: 233  QQQ------QQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQAL 286

Query: 2266 QQQMGS------------PVQPNPMSPQQHMLPNQAQSPHL--QGQQIPNSLSNQ----- 2306
             QQ+              P QP     Q   LP Q+Q+  L  Q Q +P  +        
Sbjct: 287  PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLK 346

Query: 2307 -VRSPQPVPSPRPQSQ----------------------------PPHSSPSPRMQPQPSP 2337
             VR+P  V  P  Q Q                            P  SSPSP  Q Q   
Sbjct: 347  FVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQ 406

Query: 2338 HHVSPQTSSPHPGLVAAQAN 2357
                P   SP PG  ++Q N
Sbjct: 407  SMPPPPQPSPQPGQPSSQPN 426



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 101/498 (20%), Positives = 174/498 (34%), Gaps = 73/498 (14%)

Query: 496 PGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSM-LHSAINSQNPMMSENASVPSLG 554
           PGQS  GM  +  M   PM ++G     T  +   SM + S    Q  +  +  ++    
Sbjct: 106 PGQSLGGMGSLGAMG-QPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ 164

Query: 555 PMPTAAQPSTTGIRKQWHEDITQDLR--NHLVHKLVQAIFPTPDPAALKDRRMENLVAYA 612
                 Q     +++Q  +   Q  +     + +  QA+         + ++ ++L+   
Sbjct: 165 QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH 224

Query: 613 RKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPG 672
            + +  + +          L  ++  + Q++ +++++  LQ Q  +       P    P 
Sbjct: 225 HQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQP---QPP 281

Query: 673 PNMGQPQPGMTSNG-------PLPDPSMIRGSVPNQMMPRITPQSGLNQF----GQMSMA 721
           P+   PQ     +        P P    +  + P+Q+ P+   Q  ++Q     GQM   
Sbjct: 282 PSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYT 341

Query: 722 QPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIP 781
           QPP+   + P +             PP+   P++QQ     Q     Q  + G+ V+   
Sbjct: 342 QPPLKFVRAPMVVQQ----------PPVQ--PQVQQQQTAVQTAQAAQMVAPGVQVSQSS 389

Query: 782 LAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGS----HIHCPQLPQPALHQNSPSPVPS 837
           L   S  +P  Q Q   S  P   P   PG   S    ++     P P+    SPSP PS
Sbjct: 390 LPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPS 449

Query: 838 RTPTPHHTPPSIGAQQP-PATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQ 896
           ++P    TP +     P P  T   PV     M P   SQA      Q       QL + 
Sbjct: 450 QSPVTARTPQNFSVPSPGPLNT---PVNPSSVMSPAGSSQA----EEQQYLDKLKQLSKY 502

Query: 897 VQPSLPAAPSADQPQQQPRSQQSTAA-------------------------------SVP 925
           ++P        D+ + + +      +                               +VP
Sbjct: 503 IEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVP 562

Query: 926 TPTAPLLPPQPATPLSQP 943
           TP  P +PP     L QP
Sbjct: 563 TPPPPPVPPTKQQYLCQP 580



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 115/431 (26%), Positives = 150/431 (34%), Gaps = 81/431 (18%)

Query: 1972 MTRGPS-GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQ 2030
            +T GP+ G    GM P G    P  S GG               M S+   GQP++++ Q
Sbjct: 88   LTGGPAAGAAGIGMPPRG----PGQSLGG---------------MGSLGAMGQPMSLSGQ 128

Query: 2031 PGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAA 2090
            P  G  G++P     VS    Q  L+  +      QQQQ              F +Q+  
Sbjct: 129  PPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQ-------------QFQQQQ-- 173

Query: 2091 KYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP 2150
                        Q  + Q Q   Q      QQ      AMQ         Q+    QQQ 
Sbjct: 174  ------------QAALQQQQQQQQQQQFQAQQS-----AMQQQFQAVVQQQQQLQQQQQQ 216

Query: 2151 QQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQ 2210
            QQ L         Q QQ       +        ++QQ  QQQQQQ A     P      Q
Sbjct: 217  QQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQ 276

Query: 2211 FQQPQGVGYPPQQQQRMQH--HMQQMQQGNMGQIGQL------PQALGAEAGASLQAYQQ 2262
              QP      PQQ Q+M H  H Q   Q     + Q       PQ+      +  QA   
Sbjct: 277  QPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336

Query: 2263 RLLQQQ------------MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP 2310
            ++L  Q               PVQP     Q  +   QA      G Q+  S    + SP
Sbjct: 337  QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSP 396

Query: 2311 QPVPSPR-PQSQPPHSSPSPRMQP-QPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPD 2368
             P    + PQS PP   PSP  QP QPS    S  +S P P   +   +P  Q     P 
Sbjct: 397  SPGQQVQTPQSMPPPPQPSP--QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ-----PS 449

Query: 2369 QNSMLSQLASN 2379
            Q+ + ++   N
Sbjct: 450  QSPVTARTPQN 460



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 66/264 (25%), Positives = 95/264 (35%), Gaps = 6/264 (2%)

Query: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQT 1868
            I Q   QQQ Q + QQ Q  ++ + +         QQ  P P+ A P        T    
Sbjct: 241  IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQ 300

Query: 1869 PQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKA-AGQVTPPTPP-QTAQPPLPGPPPAAV 1926
            P P  Q  P   N      P++Q    VSQ +A  GQ+    PP +  + P+    P   
Sbjct: 301  PPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360

Query: 1927 EMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
                Q Q A +T +    V    +  Q  +P ++  +P      P +  P     P  G 
Sbjct: 361  PQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 420

Query: 1987 TGMQQQPPWSQGGLPQPQQ-LQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISP---LK 2042
               Q     S G  P P   L S  P+P+   V          P PG     ++P   + 
Sbjct: 421  PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 480

Query: 2043 PGTVSQQALQNLLRTLRSPSSPLQ 2066
            P   SQ   Q  L  L+  S  ++
Sbjct: 481  PAGSSQAEEQQYLDKLKQLSKYIE 504



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 95/386 (24%), Positives = 128/386 (33%), Gaps = 60/386 (15%)

Query: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869
            +Q   QQQ Q + QQ    ++     Q   VV QQQ L                   Q  
Sbjct: 173  QQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQ 232

Query: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGP-PPAAVEM 1928
            Q   Q Q      +     + Q      Q + A Q  PP      QPP+  P PP +  +
Sbjct: 233  QQQQQLQRIAQLQLQQ--QQQQQQQQQQQQQQALQAQPP----IQQPPMQQPQPPPSQAL 286

Query: 1929 AMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTG 1988
              Q+Q       QM H Q  Q P Q Q PP+    P  + P   T+ P       +    
Sbjct: 287  PQQLQ-------QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ-PLVSQAQALPGQM 338

Query: 1989 MQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQ 2048
            +  QPP      P   Q     P+      A           PG+               
Sbjct: 339  LYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV--------------- 383

Query: 2049 QALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQ 2108
            Q  Q+ L  L SP SP QQ Q        PQ +               PQP P QPG P 
Sbjct: 384  QVSQSSLPMLSSP-SPGQQVQ-------TPQSMP------------PPPQPSP-QPGQPS 422

Query: 2109 GQP--GLQPPTMPGQQGVHSNPAMQ-NMNPMQAGV-QRAGLPQQQPQQQLQPPMGGMSPQ 2164
             QP   +     P       +P+ Q + +P+ A   Q   +P   P      P   MSP 
Sbjct: 423  SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 482

Query: 2165 A-----QQMNMNHNTMPSQFRDILRR 2185
                  +Q  ++     S++ + LRR
Sbjct: 483  GSSQAEEQQYLDKLKQLSKYIEPLRR 508



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 17/159 (10%)

Query: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLP---SPTPATPT-TPTGQQPT 1864
            ++Q   Q Q+Q   QQ  +   + A M   GV   Q  LP   SP+P     TP    P 
Sbjct: 354  VQQPPVQPQVQQ--QQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411

Query: 1865 ---TPQTPQPTSQPQ--------PTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQT 1913
               +PQ  QP+SQP         P+P + +P   P+   +   ++      V  P P  T
Sbjct: 412  PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNT 471

Query: 1914 AQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPI 1952
               P     PA    A + Q   + ++   +++  +R I
Sbjct: 472  PVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMI 510



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 34/120 (28%), Positives = 45/120 (37%), Gaps = 27/120 (22%)

Query: 445 VGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMR 504
           V Q S P LS+ S   P    +   ++  P Q +  P QP  Q  +  +  P  SP    
Sbjct: 385 VSQSSLPMLSSPS---PGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFL 441

Query: 505 PMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPST 564
           P    S SP      V  +TP                    +N SVPS GP+ T   PS+
Sbjct: 442 P----SPSPQPSQSPVTARTP--------------------QNFSVPSPGPLNTPVNPSS 477



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 63/281 (22%), Positives = 90/281 (32%), Gaps = 49/281 (17%)

Query: 469 AALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLL 528
           A L L  Q  Q   Q Q Q +  Q Q P Q P   +P    S +            P  L
Sbjct: 242 AQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA-----------LPQQL 290

Query: 529 SDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLV 588
               +H   + Q P   +   V    P     Q  T  +  Q      Q L      K V
Sbjct: 291 --QQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFV 348

Query: 589 QAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKR 648
           +A      P                + +    ++A   A+   ++A  +   Q  L    
Sbjct: 349 RAPMVVQQPPV--------------QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--- 391

Query: 649 RTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITP 708
                  +  P      P SM P P    PQPG  S+ P  + S      P+  +P  +P
Sbjct: 392 ----MLSSPSPGQQVQTPQSM-PPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446

Query: 709 QSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPM 749
           Q           +Q P+  R TP    +  +  PG LN P+
Sbjct: 447 QP----------SQSPVTAR-TP---QNFSVPSPGPLNTPV 473


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 87/390 (22%), Positives = 120/390 (30%), Gaps = 28/390 (7%)

Query: 671  PGPNMGQPQPGMTSNGPLP-----DPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPI 725
            P P    P P  TS   LP      P     + P        P +        +   PPI
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 726  VPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPS 785
                TPP       + P     P    P    P+      P T  PS        P A +
Sbjct: 1459 STTTTPPPTTTP--SPPTTTPSPPTTTP--SPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514

Query: 786  SGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT 845
            +   P +     +++     P   P    +    P  P  +     P+  PS  PT   T
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTT---TPITPPTSTTTLPPTTTPSPPPTTTTT 1571

Query: 846  PPSIGAQQPPATTIPAP------VPTPPAMPPGPQSQALHPPPRQTPTPP---------- 889
            PP      PP TT P+P       P P   P  P +    PPP  TP+PP          
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631

Query: 890  TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEG 949
            TT LP    PS P   +   P     S  +T    P  T    PP   TP S    +   
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691

Query: 950  QVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMES 1009
              +   + S T   S  I            +        P+ T       + +      +
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751

Query: 1010 TETEERSTELKTEIKEEEDQPSTSATQSSP 1039
            T +   +T L   I      P ++ T ++P
Sbjct: 1752 TSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 47/151 (31%), Positives = 60/151 (39%), Gaps = 11/151 (7%)

Query: 819  CPQLPQPALHQNSPSPVPSRT--PTPHHTPPSIGAQQPPATTIPAP------VPTPPAMP 870
            C   P P     SP P  + T  PT   +PP+     PP TT P+P       P P   P
Sbjct: 1395 CITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 871  PGPQSQALHPPPRQTPTPP-TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTA 929
              P S    PPP  TP+PP TT  P    PS P   +   P     S  +T    P  + 
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514

Query: 930  PLLPP--QPATPLSQPAVSIEGQVSNPPSTS 958
              LPP   P+ P +           +PP+T+
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 72/306 (23%), Positives = 105/306 (34%), Gaps = 48/306 (15%)

Query: 659  PNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQM 718
            P +   +P +  P P    P    T+  P   PS      P    P ITP +        
Sbjct: 1511 PASTTTLPPTTTPSP----PTTTTTTPPPTTTPS------PPTTTP-ITPPTSTTTLPPT 1559

Query: 719  SMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVT 778
            +   PP     TPP             +PP    P    P+      P T  PS     T
Sbjct: 1560 TTPSPPPTTTTTPP--------PTTTPSPPTTTTP--SPPTITTTTPPPTTTPSPPTTTT 1609

Query: 779  NIPLAPSSGQ----APVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSP 834
              P   ++       P++    +++  P  +P  PP +  +       P P     +PSP
Sbjct: 1610 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT-------PPPT---TTPSP 1659

Query: 835  VPSRTPTPH----HTPPSIGAQQPPATTIPAP------VPTPPAMPPGPQSQALHPPPRQ 884
              + TP+P      TPP       P TT P+P       P+P   P  P +    P    
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT 1719

Query: 885  TPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTP---TAPLLPPQPATPLS 941
            TP+PP T +      + P+ P+       P +  S   + P P   T P   P   T  +
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779

Query: 942  QPAVSI 947
             P V +
Sbjct: 1780 TPCVPL 1785



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 45/137 (32%), Positives = 60/137 (43%), Gaps = 26/137 (18%)

Query: 831  SPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPP- 889
            +PSP P+ TP+P   PP+     PP TT     P+PP       +    PPP  TP+PP 
Sbjct: 1398 TPSP-PTTTPSP---PPTSTTTLPPTTT-----PSPPT------TTTTTPPPTTTPSPPI 1442

Query: 890  --TTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPT-----PTAPLLPPQPATPLSQ 942
              TT  P    PS P + +   P     S  +T  S PT     PT     P P T  S 
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502

Query: 943  PAVSIEGQVSNPPSTSS 959
            P  +    ++ P ST++
Sbjct: 1503 PTTT---PITPPASTTT 1516



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 48/203 (23%), Positives = 75/203 (36%), Gaps = 22/203 (10%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 4096 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 4150

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQA 877
                 P       +P+P P+ T TP  TP +        TT   P PTP     GP    
Sbjct: 4151 --TTTPITTTTTVTPTPTPTGTQTPTTTPIT-------TTTTVTPTPTPTGTQTGP---- 4197

Query: 878  LHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA 937
                P  T T P  +L     P   + P   +    P ++ +T  S   P   +    P 
Sbjct: 4198 ----PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 4253

Query: 938  TPLSQPAVSIEGQVSNPPSTSST 960
            +  + P  +  G   +PP +++T
Sbjct: 4254 STPTAPTTTSGGHTLSPPPSTTT 4276



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 59/217 (27%), Positives = 82/217 (37%), Gaps = 25/217 (11%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 4081

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTP-----PAMPPG 872
                 P       +P+P P+ T TP  TP +        TT   P PTP     P   P 
Sbjct: 4082 --TTTPITTTTTVTPTPTPTGTQTPTTTPIT-------TTTTVTPTPTPTGTQTPTTTPI 4132

Query: 873  PQSQALHPPPRQT--PTPPTTQLPQQVQPSLPAAPSADQ-PQQQPRSQQSTAASVPTPTA 929
              +  + P P  T   TP TT +      +    P+  Q P   P +  +T    PTPT 
Sbjct: 4133 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4192

Query: 930  PLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQA 966
                P   T  +  A   E   SNPP  SST   S++
Sbjct: 4193 TQTGPPTHTSTAPIA---ELTTSNPPPESSTPQTSRS 4226



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 57/244 (23%), Positives = 73/244 (29%), Gaps = 33/244 (13%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQP------TPPNSMPPYLPRTQAAGPVSQGKA 1901
            P+ TP+ PTT      TT  TP PT+ P P      TPP S     P T  + P +    
Sbjct: 1473 PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT 1532

Query: 1902 AGQVTPPTPPQTA--QPP----------LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQ 1949
                T P+PP T    PP           P PPP            +             
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT 1592

Query: 1950 RPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSG 2009
                      +P       PPP T        P   PT     PP +    P P    + 
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT---TPSPPPTTTT 1649

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQV-----GISPLKPGTVSQQALQNLLRT---LRSP 2061
             P P          P    P P +          +P  P T +       + T     +P
Sbjct: 1650 TPPP----TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 2062 SSPL 2065
            SSP+
Sbjct: 1706 SSPI 1709



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 48/165 (29%), Positives = 57/165 (34%), Gaps = 19/165 (11%)

Query: 1848 PSP------TPATPTTPTGQQPTTPQTPQPTSQPQP------TPPNSMPPYLPRTQAAGP 1895
            PSP      TP   TTP+    TT  TP PT+ P P      TPP S     P T  + P
Sbjct: 1586 PSPPTITTTTPPPTTTPS-PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 1896 VSQGKAAGQVTPPTPPQTAQPPLP-----GPPPAAVEMAMQIQRAAETQRQMAHVQIFQR 1950
             +        T P+PP T  P  P      PPP     +      +     M        
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704

Query: 1951 PIQHQMPPMTPMAPMGMNPPPMT-RGPSGHLEPGMGPTGMQQQPP 1994
            P        TP +    +PPP T   PS    P    T M   PP
Sbjct: 1705 PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 34/128 (26%), Positives = 43/128 (33%), Gaps = 3/128 (2%)

Query: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPP 1908
            S T   PTT     PTT  TP PT+ P P    +  P +  T    P +   +    TP 
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690

Query: 1909 TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMN 1968
             P  T   P P   P++         +  T            P     PP T M  +   
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL--- 1747

Query: 1969 PPPMTRGP 1976
            PP  T  P
Sbjct: 1748 PPTTTSSP 1755



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 48/180 (26%), Positives = 58/180 (32%), Gaps = 20/180 (11%)

Query: 1851 TPATPTTPTGQQPTTPQTPQPTSQPQP------TPPNSMPPYLPRTQAAGP---VSQGKA 1901
            TP+ PTT     PT+  T  PT+ P P      TPP +  P  P T    P    +    
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 1902 AGQVTPPTPPQTAQPP--LPGPP---PAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQM 1956
                T P P  T  PP   P PP   P+             T        I        +
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL 1517

Query: 1957 PPMTPMAP---MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRP 2013
            PP T  +P       PPP T        P   PT     PP +    P P    +  P P
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT---TPSPPPTTTTTPPP 1574



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 1965

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 1966 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2023

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2024 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2080

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2081 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2139

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2192

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2193 QTPTTTPITTTTTVTPTP 2210



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2126

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2127 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2185 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2241

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2300

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2353

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2354 QTPTTTPITTTTTVTPTP 2371



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2287

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2288 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2345

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2346 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2402

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2461

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2514

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2515 QTPTTTPITTTTTVTPTP 2532



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2394 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2448

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2449 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2506

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2507 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2563

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2622

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2675

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2676 QTPTTTPITTTTTVTPTP 2693



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2609

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2610 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2668 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2724

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2783

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2836

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2837 QTPTTTPITTTTTVTPTP 2854



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2770

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2771 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2828

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2829 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 2885

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2944

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 2997

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 2998 QTPTTTPITTTTTVTPTP 3015



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 2931

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 2932 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2989

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 2990 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3046

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3105

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3158

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3159 QTPTTTPITTTTTVTPTP 3176



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3092

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3093 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3151 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3207

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3266

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3319

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3320 QTPTTTPITTTTTVTPTP 3337



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3253

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3254 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3312 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3368

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3427

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3480

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3481 QTPTTTPITTTTTVTPTP 3498



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3414

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3415 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3473 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3529

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3588

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3641

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3642 QTPTTTPITTTTTVTPTP 3659



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3575

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3576 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3634 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3690

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3749

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3802

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3803 QTPTTTPITTTTTVTPTP 3820



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3736

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3737 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3794

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3795 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 3851

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3910

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 3963

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 3964 QTPTTTPITTTTTVTPTP 3981



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 74/318 (23%), Positives = 107/318 (33%), Gaps = 52/318 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 3897

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPV 863
                 P       +P+P P+ T TP  TP +            G Q P   P TT     
Sbjct: 3898 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3955

Query: 864  PTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQP 910
            PTP   P G Q+    P         TPTP  TQ P          V P+ P       P
Sbjct: 3956 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTP 4012

Query: 911  QQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
               P +  +T    PTP       T P+      TP   P    +   + P +T++T   
Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 4071

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEI 1023
            +      Q      +     V  P P  T  +  + + +      +T T    T   T  
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGT 4124

Query: 1024 KEEEDQPSTSATQSSPAP 1041
            +     P T+ T  +P P
Sbjct: 4125 QTPTTTPITTTTTVTPTP 4142



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 38/142 (26%), Positives = 54/142 (38%), Gaps = 10/142 (7%)

Query: 858  TIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQL---PQQVQPSLPAAPSADQPQQQP 914
            T P+P  T P+ PP   S     PP  TP+PPTT     P    PS P   +   P    
Sbjct: 1397 TTPSPPTTTPSPPP--TSTTT-LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT 1453

Query: 915  RSQQSTAASVPTPTAPLLPP--QPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP 972
             S   +  + P PT    PP   P+ P + P+       + PP+T+ +   +  I    P
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT--PP 1511

Query: 973  SQEVKMEAKMEVDQPEPADTQP 994
            +    +        P    T P
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTP 1533



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 55/220 (25%), Positives = 82/220 (37%), Gaps = 32/220 (14%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 4127

Query: 818  HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQA 877
                 P       +P+P P+ T TP  TP +        TT   P PTP      P +  
Sbjct: 4128 --TTTPITTTTTVTPTPTPTGTQTPTTTPIT-------TTTTVTPTPTPTGTQT-PTTTP 4177

Query: 878  LHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPL------ 931
            +      TPTP  T            AP A+     P  + ST  +  + ++PL      
Sbjct: 4178 ITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL 4237

Query: 932  ---LPP--------QPATPLSQPAVSIEGQVSNPPSTSST 960
               LPP         P+TP +    S    +S PPST+++
Sbjct: 4238 LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 4277



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 59/245 (24%), Positives = 83/245 (33%), Gaps = 45/245 (18%)

Query: 831  SPSPVPSRTPTPHHTPPSI-----------GAQQP---PATTIPAPVPTPPAMPPGPQSQ 876
            +P+P P+ T TP  TP +            G Q P   P TT     PTP   P G Q+ 
Sbjct: 1908 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTP 1965

Query: 877  ALHP-----PPRQTPTPPTTQLP--------QQVQPSLPAAPSADQPQQQPRSQQSTAAS 923
               P         TPTP  TQ P          V P+ P       P   P +  +T   
Sbjct: 1966 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2024

Query: 924  VPTP-------TAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEV 976
             PTP       T P+      TP   P    +   + P +T++T   +      Q     
Sbjct: 2025 TPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2083

Query: 977  KMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQ 1036
             +     V  P P  T  +  + + +      +T T    T   T  +     P T+ T 
Sbjct: 2084 PITTTTTV-TPTPTPTGTQTPTTTPI------TTTTTVTPTPTPTGTQTPTTTPITTTTT 2136

Query: 1037 SSPAP 1041
             +P P
Sbjct: 2137 VTPTP 2141



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 1851 TPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPT- 1909
            TP++ TTP+   PTT  TP PT+   P+PP +    LP T  + P++       +TPPT 
Sbjct: 1714 TPSSTTTPS-PPPTTMTTPSPTT--TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770

Query: 1910 -PPQTAQPPLPGPP 1922
             P  T  P  P  P
Sbjct: 1771 SPFSTTTPTTPCVP 1784



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 45/170 (26%), Positives = 56/170 (32%), Gaps = 19/170 (11%)

Query: 1848 PSPTPATPTTPTGQQP--TTPQ-------TPQPTSQPQ-----PTPPNSMPPYLPRTQAA 1893
            P+ TP+ P T T   P  TTP        TP PT+ P      P+PP + P     T   
Sbjct: 1434 PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493

Query: 1894 GPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQ 1953
             P +   +    TP TPP +     P   P+             T        I      
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 1954 HQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQP 2003
              +PP T  +P    PP  T  P     P   PT     PP      P P
Sbjct: 1554 TTLPPTTTPSP----PPTTTTTPPPTTTPS-PPTTTTPSPPTITTTTPPP 1598



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 35/130 (26%), Positives = 49/130 (37%), Gaps = 16/130 (12%)

Query: 1848 PSPTPATPTTPTGQQP-TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVT 1906
            P+ TP+ PTT T   P TT  TP PT+ P  + P +  P  P T    P      +  +T
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTP--SSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710

Query: 1907 PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMG 1966
              T P +     P PPP  +         +     M             +PP T  +P+ 
Sbjct: 1711 TTTTPSSTTT--PSPPPTTMTTPSPTTTPSPPTTTMT-----------TLPPTTTSSPLT 1757

Query: 1967 MNPPPMTRGP 1976
              P P +  P
Sbjct: 1758 TTPLPPSITP 1767



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 94/454 (20%), Positives = 139/454 (30%), Gaps = 83/454 (18%)

Query: 659  PNAAGMVPVSMNPGP---NMGQPQPGMTSNGPL-----------PDPSMIRGSVPNQMMP 704
            P      P++  P P    M  P P  T + P+           P P     + P+    
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT 1736

Query: 705  RITPQSGLNQFGQMSMAQP----PIVPRQTPPLQHHGQLAQPGALNPPM--------GYG 752
               P + +      + + P    P+ P  TPP         P     P+           
Sbjct: 1737 PSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGK 1796

Query: 753  PRMQQPSNQGQFLPQTQFPSQGMNV----TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM 808
            P   +P    + +     P    N+    T  P  P           +S      N    
Sbjct: 1797 PNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQK 1856

Query: 809  PPG--------SQGSHIHCPQ-LPQPALHQNS----PSPVPSRTP-----TPHHTPPSIG 850
            P G        +   ++ C + + QP     +    P+P P+ TP     T   TP   G
Sbjct: 1857 PGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP-PTTTPITTTTTVTPTPTPTG 1915

Query: 851  AQQP---PATTIPAPVPTPPAMPPGPQSQALHP-----PPRQTPTPPTTQLP-------- 894
             Q P   P TT     PTP   P G Q+    P         TPTP  TQ P        
Sbjct: 1916 TQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973

Query: 895  QQVQPSLPAAPSADQPQQQPRSQQSTAASVPTP-------TAPLLPPQPATPLSQPAVSI 947
              V P+ P       P   P +  +T    PTP       T P+      TP   P    
Sbjct: 1974 TTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGT 2031

Query: 948  EGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKM 1007
            +   + P +T++T   +      Q      +     V  P P  T  +  + + +     
Sbjct: 2032 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPI----- 2085

Query: 1008 ESTETEERSTELKTEIKEEEDQPSTSATQSSPAP 1041
             +T T    T   T  +     P T+ T  +P P
Sbjct: 2086 -TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 60/225 (26%), Positives = 72/225 (32%), Gaps = 24/225 (10%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 4048 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 4158

Query: 1966 GMNPPPMTRGPSGHLEPGMGP-TGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQP 2024
                P  T  P+G   P   P T      P      P P   Q+G P     +       
Sbjct: 4159 TTVTPTPT--PTGTQTPTTTPITTTTTVTP-----TPTPTGTQTGPPTHTSTAPIAELTT 4211

Query: 2025 LNMAPQPGLGQVGISPLKPGTVSQQALQNL-----LRTLRSPSSP 2064
             N  P+    Q   S   P T S   L  L     + +   PS+P
Sbjct: 4212 SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 51/213 (23%), Positives = 67/213 (31%), Gaps = 14/213 (6%)

Query: 1777 GGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQ-LQHRLQQAQMLRRRMASM 1835
            G   +C   + L C +         P+ FCLN +  ++  + +                 
Sbjct: 1837 GQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPP 1896

Query: 1836 QRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAG 1894
              T +       P+PTP    TPT    TTP T   T  P PTP  +  P   P T    
Sbjct: 1897 TTTPITTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952

Query: 1895 PVSQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQ 1953
                    G  TP T P T    + P P P   +          T      V     P  
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTG 2007

Query: 1954 HQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             Q P  TP+       P  T  P+G   P   P
Sbjct: 2008 TQTPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2038



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 1978 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2088

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2089 TTVTPTPT--PTGTQTPTTTP 2107



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2047 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2102

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2157

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2158 TTVTPTPT--PTGTQTPTTTP 2176



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2116 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2171

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2226

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2227 TTVTPTPT--PTGTQTPTTTP 2245



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2185 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2295

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2296 TTVTPTPT--PTGTQTPTTTP 2314



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2254 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2364

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2365 TTVTPTPT--PTGTQTPTTTP 2383



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2323 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2433

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2434 TTVTPTPT--PTGTQTPTTTP 2452



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2392 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2502

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2503 TTVTPTPT--PTGTQTPTTTP 2521



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2461 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2571

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2572 TTVTPTPT--PTGTQTPTTTP 2590



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2530 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2640

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2641 TTVTPTPT--PTGTQTPTTTP 2659



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2599 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2654

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2709

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2710 TTVTPTPT--PTGTQTPTTTP 2728



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2668 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2778

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2779 TTVTPTPT--PTGTQTPTTTP 2797



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2737 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2792

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2847

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2848 TTVTPTPT--PTGTQTPTTTP 2866



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2806 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2916

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2917 TTVTPTPT--PTGTQTPTTTP 2935



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2875 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 2985

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 2986 TTVTPTPT--PTGTQTPTTTP 3004



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 2944 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2999

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3054

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3055 TTVTPTPT--PTGTQTPTTTP 3073



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3013 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3123

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3124 TTVTPTPT--PTGTQTPTTTP 3142



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3082 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3192

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3193 TTVTPTPT--PTGTQTPTTTP 3211



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3151 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3261

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3262 TTVTPTPT--PTGTQTPTTTP 3280



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3220 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3330

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3331 TTVTPTPT--PTGTQTPTTTP 3349



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3289 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3399

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3400 TTVTPTPT--PTGTQTPTTTP 3418



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3358 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3468

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3469 TTVTPTPT--PTGTQTPTTTP 3487



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3427 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3537

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3538 TTVTPTPT--PTGTQTPTTTP 3556



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3496 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3606

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3607 TTVTPTPT--PTGTQTPTTTP 3625



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3565 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3675

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3676 TTVTPTPT--PTGTQTPTTTP 3694



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3634 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3744

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3745 TTVTPTPT--PTGTQTPTTTP 3763



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3703 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3813

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3814 TTVTPTPT--PTGTQTPTTTP 3832



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3772 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3882

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3883 TTVTPTPT--PTGTQTPTTTP 3901



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3841 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 3951

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 3952 TTVTPTPT--PTGTQTPTTTP 3970



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3910 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3965

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 4020

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 4021 TTVTPTPT--PTGTQTPTTTP 4039



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 41/141 (29%), Positives = 47/141 (33%), Gaps = 13/141 (9%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-PPYLPRTQAAGPVSQGKAAGQVT 1906
            P+PTP    TPT    TTP T   T  P PTP  +  P   P T            G  T
Sbjct: 3979 PTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4034

Query: 1907 PPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPM 1965
            P T P T    + P P P   +          T      V     P   Q P  TP+   
Sbjct: 4035 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTPTTTPITTT 4089

Query: 1966 GMNPPPMTRGPSGHLEPGMGP 1986
                P  T  P+G   P   P
Sbjct: 4090 TTVTPTPT--PTGTQTPTTTP 4108



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 54/210 (25%), Positives = 69/210 (32%), Gaps = 33/210 (15%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTP-----PNSMPPYLPRTQA 1892
            P+ TP T TT   PT   PT  QTP  T         P PTP     P + P     T  
Sbjct: 4127 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4185

Query: 1893 AGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPI 1952
              P   G   G  T  +    A+     PPP +     Q  R+  +    +   +   P 
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPES--STPQTSRSTSSPLTESTTLLSTLPP 4243

Query: 1953 QHQM----PPMTPMAPMGMN-------PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLP 2001
              +M    PP TP AP   +       PP  T  P G   P  G T      P       
Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG--TPTRGTTTGSSSAP--TPSTV 4299

Query: 2002 QPQQLQSGMPRPAMMSVAQHGQPLNMAPQP 2031
            Q     +  P P  +S     +   + P P
Sbjct: 4300 QTTTTSAWTPTPTPLSTPSIIRTTGLRPYP 4329



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 55/212 (25%), Positives = 79/212 (37%), Gaps = 35/212 (16%)

Query: 758  PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
            P+  G   P T   +    VT  P  P+  Q P +    ++++  V     P G+Q    
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTT--VTPTPTPTGTQTP-- 4173

Query: 818  HCPQLPQPALHQNSPSPVPSRTPT--PHHT--------------PPSIGAQQPPATTIPA 861
                 P       +P+P P+ T T  P HT              P S   Q   +T+ P 
Sbjct: 4174 --TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL 4231

Query: 862  PVPTP--PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQS 919
               T     +PP  +  +  PP   TPT PTT        S P + +   P    R   +
Sbjct: 4232 TESTTLLSTLPPAIEMTSTAPP--STPTAPTTTSGGHTL-SPPPSTTTSPPGTPTRGTTT 4288

Query: 920  TAASVPTP------TAPLLPPQPATPLSQPAV 945
             ++S PTP      T     P P TPLS P++
Sbjct: 4289 GSSSAPTPSTVQTTTTSAWTPTP-TPLSTPSI 4319



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 51/205 (24%), Positives = 75/205 (36%), Gaps = 38/205 (18%)

Query: 766  PQTQFPSQGMNVTNIPLAPSSGQ-APVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQ 824
            P++  P Q    T+ PL  S+   + +  A   +S+ P ++P  P  + G H   P    
Sbjct: 4216 PESSTP-QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP---- 4270

Query: 825  PALHQNSPSPVPSR-TPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPR 883
            P     SP   P+R T T   + P+    Q   T+   P PTP + P   ++  L P P 
Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 4330

Query: 884  QT----PTPPTTQLPQQ-------------VQPSLP--------AAPSADQPQQQPRSQQ 918
                      T   P +             V  SL         + PS   P   P    
Sbjct: 4331 SVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP---- 4386

Query: 919  STAASVPTPTAPLLPPQPATPLSQP 943
              + S PTP+ P   P   TP ++P
Sbjct: 4387 --SKSTPTPSKPSSTPSKPTPGTKP 4409



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 36/133 (27%), Positives = 47/133 (35%), Gaps = 16/133 (12%)

Query: 1856 TTPTGQQPTTPQTPQPTS------QPQPTPP---NSMPPYLPRTQAAGPVSQGKAAGQVT 1906
            TTP+   PTT  +P PTS         P+PP    + PP  P T  + P++        T
Sbjct: 1397 TTPS--PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP--PTTTPSPPITTTTTPPPTT 1452

Query: 1907 PPTPP---QTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963
             P+PP    T  PP   P P     +      +              P      P+TP A
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 1964 PMGMNPPPMTRGP 1976
                 PP  T  P
Sbjct: 1513 STTTLPPTTTPSP 1525



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 73/284 (25%), Positives = 90/284 (31%), Gaps = 39/284 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 4012 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 4125

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP-TGMQQQPPWSQGGLPQPQQLQSGMPRPA 2014
             P  TP+       P  T  P+G   P   P T      P      P P   Q+    P 
Sbjct: 4126 TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPI 4178

Query: 2015 MMSVAQHGQPLNMAPQPG-LGQVGISPLKPGTVSQQALQNLL-RTLRSPSSPLQQQQVLS 2072
              +      P     Q G       +P+   T S    ++   +T RS SSPL +   L 
Sbjct: 4179 TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL- 4237

Query: 2073 ILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP 2116
             L   P          A +  ++ P   P  P    G   L PP
Sbjct: 4238 -LSTLPP---------AIEMTSTAPPSTPTAPTTTSGGHTLSPP 4271



 Score = 37.0 bits (84), Expect = 0.24
 Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 37/230 (16%)

Query: 670  NPGPNMGQPQPGMTSNGPLPDPSMIRGSVP-----NQMMPRITPQSGLNQFGQMSMAQPP 724
            NP P    PQ   +++ PL + + +  ++P         P  TP +     G  +++ PP
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 4272

Query: 725  IVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAP 784
                  P     G     G+ + P    P   Q +    + P T  P     ++   +  
Sbjct: 4273 STTTSPPGTPTRG--TTTGSSSAPT---PSTVQTTTTSAWTP-TPTP-----LSTPSIIR 4321

Query: 785  SSGQAPVSQAQMSSSSCPVNSPIMPPGSQ---GSH------IHCPQLPQPALHQNSPSPV 835
            ++G  P   + +    C +N     PG +   G++      ++C        +  S    
Sbjct: 4322 TTGLRPYPSSVL--ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST 4379

Query: 836  PSRTPTPHHTPPSIGAQQPPAT-TIPAPVPTPPAMPPGPQSQALHPPPRQ 884
            PS TPTP  + P+    +P +T + P P   PP  P          PPRQ
Sbjct: 4380 PSPTPTPSKSTPT--PSKPSSTPSKPTPGTKPPECPD-------FDPPRQ 4420



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2057 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2170

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2171 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2199



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2080 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2138

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2193

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2194 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2222



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2126 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2239

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2240 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2268



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2149 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2207

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2262

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2263 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2291



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2195 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2253

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2308

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2309 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2337



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2218 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2276

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2331

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2332 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2360



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2264 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2322

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2377

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2378 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2406



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2287 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2345

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2400

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2401 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2429



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2333 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2391

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2446

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2447 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2475



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2356 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2469

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2470 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2498



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2402 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2515

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2516 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2544



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2425 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2538

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2539 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2567



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2471 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2584

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2585 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2613



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2494 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2607

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2608 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2636



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2540 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2653

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2654 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2682



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2563 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2676

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2677 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2705



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2609 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2722

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2723 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2751



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2632 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2745

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2746 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2774



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2678 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2736

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2791

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2792 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2820



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2701 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2759

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2814

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2815 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2843



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2747 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2860

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2861 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2889



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2770 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2828

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2883

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2884 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2912



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2816 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2929

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2930 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2958



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2839 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2952

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2953 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2981



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2885 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2943

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 2998

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 2999 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3027



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2908 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3021

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3022 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3050



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2954 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3012

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3067

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3068 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3096



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 2977 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3035

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3090

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3091 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3119



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3023 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3136

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3137 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3165



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3046 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3104

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3159

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3160 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3188



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3092 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3205

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3206 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3234



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3115 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3228

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3229 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3257



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3161 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3274

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3275 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3303



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3184 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3297

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3298 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3326



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3230 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3288

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3343

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3344 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3372



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3253 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3366

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3367 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3395



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3299 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3412

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3413 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3441



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3322 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3380

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3435

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3436 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3464



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3368 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3426

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3481

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3482 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3510



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3391 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3449

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3504

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3505 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3533



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3437 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3495

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3550

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3551 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3579



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3460 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3573

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3574 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3602



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3506 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3564

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3619

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3620 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3648



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3529 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3587

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3642

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3643 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3671



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3575 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3688

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3689 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3717



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3598 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3656

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3711

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3712 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3740



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3644 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3702

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3757

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3758 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3786



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3667 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3780

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3781 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3809



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3713 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3771

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3826

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3827 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3855



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3736 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3794

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3849

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3850 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3878



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3782 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3895

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3896 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3924



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3805 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3863

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3918

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3919 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3947



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3851 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3909

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3910 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3964

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3965 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 3993



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3874 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3932

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 3987

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 3988 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 4016



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3920 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3978

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 4033

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 4034 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 4062



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/151 (28%), Positives = 49/151 (32%), Gaps = 20/151 (13%)

Query: 1848 PSPTPATPTT---PTGQQPTTPQTPQPTS-------QPQPTPPNSM-PPYLPRTQAAGPV 1896
            P+ TP T TT   PT   PT  QTP  T         P PTP  +  P   P T      
Sbjct: 3943 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001

Query: 1897 SQGKAAGQVTPPTPPQTAQPPL-PGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQ 1955
                  G  TP T P T    + P P P   +          T      V     P   Q
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQ 4056

Query: 1956 MPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
             P  TP+       P  T  P+G   P   P
Sbjct: 4057 TPTTTPITTTTTVTPTPT--PTGTQTPTTTP 4085



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 3/40 (7%)

Query: 1848 PSPTPA-TPTTPTGQQPT-TPQTPQPTSQPQPTPPNSMPP 1885
            PSPTP  + +TPT  +P+ TP  P P ++P P  P+  PP
Sbjct: 4380 PSPTPTPSKSTPTPSKPSSTPSKPTPGTKP-PECPDFDPP 4418


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 88/336 (26%), Positives = 126/336 (37%), Gaps = 39/336 (11%)

Query: 673 PNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ-SGLNQFGQMSMAQPPIVPRQTP 731
           P  G P P   S  P P P ++    P  M P   P    L+    +S    P  P   P
Sbjct: 157 PPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216

Query: 732 PLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPV 791
           P      LA P    PP    P    P++    +    FP  G+      +A +  QA  
Sbjct: 217 PAPPLAFLAPP----PPPVPAPAPPAPASP-HTVGTRLFPPGGVTKWKSDVALNGRQAEA 271

Query: 792 SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP--PSI 849
           ++A       P  SP  P GS          P P  H   P       PTP  T   P  
Sbjct: 272 TRAS------PPRSPAEPKGSALG-------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318

Query: 850 GAQQPP------ATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA 903
            AQ+ P          P+ +P PP+    P SQ     P + P P     P +++ + PA
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVY---PDRAPEP---DCPGELKATAPA 372

Query: 904 APSADQPQQQPRSQQST---AASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPS--TS 958
           +P   Q Q Q   +  T   A  +P P  PL PP P  P + P +    + ++PP+  T 
Sbjct: 373 SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTK 432

Query: 959 STEVNSQAIAEK-QPSQEVKMEAKMEVDQPEPADTQ 993
           + + +S A+  K  P       +   VD  +P+  +
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 55/216 (25%), Positives = 76/216 (35%), Gaps = 20/216 (9%)

Query: 810  PGSQGSHIHCPQLPQ---PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTP 866
            PG  G  +  P  P    P   Q+   P P  +P P  +PPS     PP   +  P P P
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEP-PGGSPLP--SPPSTAPPPPPL--LLEPPPPP 184

Query: 867  PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPT 926
               PP P       PP    +P     P  + P+ P A  A  P   P       AS  T
Sbjct: 185  SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244

Query: 927  PTAPLLPPQPATPLSQPAVSIEGQVSN----PPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
                L PP   T      V++ G+ +      P  S  E    A+    P   +      
Sbjct: 245  VGTRLFPPGGVTKWKSD-VALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTFPRSF 302

Query: 983  EVDQPEPADTQPEDISESKVEDCKMESTETEERSTE 1018
            +V  P P  T    + E++      E+   EE +T+
Sbjct: 303  KVPPPTPVRTSSIPVQEAQ------EAPRKEEGATK 332



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 58/277 (20%), Positives = 96/277 (34%), Gaps = 29/277 (10%)

Query: 704 PRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQ 763
           P + PQS   + G       P +P +   L    +   PG     +G     +  +    
Sbjct: 494 PTVAPQSKEGKKG-------PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546

Query: 764 FLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLP 823
            LP   +  Q     ++    +  +A +S A    +   + S  +PP         P+L 
Sbjct: 547 TLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS--LPPK--------PRLE 596

Query: 824 QPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPR 883
              + +N         P   + PP       P T++       PA+PP    +   PP  
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQ-STTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655

Query: 884 QT--PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
                TPP   L         + P+         +  STA ++PT T+ L+  + + P  
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKM 978
           QP      +VS P         SQA  E  PS+  ++
Sbjct: 716 QPEKPASQEVSTP---------SQARGEGSPSEATRL 743



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 73/318 (22%), Positives = 101/318 (31%), Gaps = 53/318 (16%)

Query: 1848 PSPTPATPT--------TPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899
            P P P  P         +P    P+T   P P     P PP+  PP  P  +A  P    
Sbjct: 144  PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203

Query: 1900 KAAGQVT-----PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ--------RQMAHVQ 1946
             +    T     PP PP     P P P PA    A        T+        +  + V 
Sbjct: 204  SSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVA 263

Query: 1947 IFQRPIQ--HQMPPMTPMAP----MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
            +  R  +     PP +P  P    +G NP P    P     P   P      P       
Sbjct: 264  LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323

Query: 2001 PQPQQ-----LQSGMPRPAMMSVAQHGQPL-NMAPQPGLGQVGISPLKPGTVSQQALQNL 2054
            P+ ++       S +P P    +    Q   + AP+P           PG +   A    
Sbjct: 324  PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC---------PGELKATA---- 370

Query: 2055 LRTLRSPSSP-LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGL 2113
                  P+SP L Q Q  +   A     A  +   A       P   P  P +P  Q   
Sbjct: 371  ------PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 2114 QPPTMPGQQGVHSNPAMQ 2131
             PP    +    S+PA++
Sbjct: 425  HPPAGFTKTPKSSSPALK 442



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 83/340 (24%), Positives = 114/340 (33%), Gaps = 72/340 (21%)

Query: 1837 RTGVVGQQQGLPSPTPATPTTPTGQQPTTPQ--TPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
            R G  GQ   +P P P       G  P  PQ  +  P   P P+PP++ PP  P      
Sbjct: 129  RPGQYGQDLLIPPPPP-------GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL---- 177

Query: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH 1954
                      + PP PP  A      PPP  V        A      ++   I   P   
Sbjct: 178  ----------LEPPPPPSMA------PPPPPV------LEALSPPHTLSSPSIPTPP--D 213

Query: 1955 QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP-----WSQGGLPQPQQLQSG 2009
             +PP  P+A +   PPP+   P+          G +  PP     W        +Q ++ 
Sbjct: 214  FIPPAPPLAFLAPPPPPVP-APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQ 2069
               P        G  L   P+P L       + P T            +R+ S P+Q+ Q
Sbjct: 273  RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT-----------PVRTSSIPVQEAQ 321

Query: 2070 VLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQ--PGLQP-PTMPGQQGVHS 2126
                        A   ++ A K A S     P     P  Q  P   P P  PG+    +
Sbjct: 322  E-----------APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA-T 369

Query: 2127 NPAMQNMNPMQAGV-QRAGLPQQQPQQQLQPPMGGMSPQA 2165
             PA   +   Q+   +RAG P   P   L PP   + P A
Sbjct: 370  APASPRLGQSQSQADERAGTP--PPAPPLPPPAPPLPPPA 407



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 111/514 (21%), Positives = 183/514 (35%), Gaps = 105/514 (20%)

Query: 653  QKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT-PQSG 711
            Q Q+     AG  P    P P +  P P +    P P P +   + P     +   P +G
Sbjct: 378  QSQSQADERAGTPP----PAPPLPPPAPPL----PPPAPPLPPAAPPLPCAQKAAHPPAG 429

Query: 712  LNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQ-GQFL----P 766
              +  + S   P + P+  PP   +   + P     P     +M++  N+   +L     
Sbjct: 430  FTKTPKSS--SPALKPKPNPPSPENTASSAPVDWRDPS----QMEKLRNELAAYLCGSRR 483

Query: 767  QTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNS--PIMPPGSQGSHIHCPQLPQ 824
            + +F S     T  P +    + P    + +  S P     P +P  S G          
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 825  PALHQNSPSPVPSRTPTP--HHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALH--- 879
            P+L   S   +P  +PTP        + A+   A    A  P+  ++PP P+ +      
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK-PSIGSLPPKPRLEGGRICE 602

Query: 880  ----------------PPPRQTPTPPTTQLPQ-QVQPSLPAAPSADQPQQQPRSQQSTAA 922
                            PP   T  P T+  P+  + P++P       P+  P       A
Sbjct: 603  NGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP-------PKATPEPAIPPKA 655

Query: 923  SVPTPTAPLLPPQPATPL------SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ--PSQ 974
            ++   T P     PATPL      + P  +  G      +T+     SQ +AEK   P+ 
Sbjct: 656  TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 975  EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSA 1034
            + +  A  EV  P          S+++ E    E+T    +               S++A
Sbjct: 716  QPEKPASQEVSTP----------SQARGEGSPSEATRLPTQGAR------------SSAA 753

Query: 1035 TQSSPAPGQSKKK-IFKPEELRQAL-------MPTL---------EALYRQDPESLPFRQ 1077
                 +PG  +   ++KP   + +L       MPTL         E +  ++P  LP + 
Sbjct: 754  FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813

Query: 1078 PVDPQ----LLGIPDYFDIVK--SPMDLSTIKRK 1105
            P   Q    LL  P   ++V+  SPM L    R+
Sbjct: 814  PASAQPTDELLRHPVTGEVVERGSPMALLLAARQ 847



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 70/321 (21%), Positives = 107/321 (33%), Gaps = 47/321 (14%)

Query: 1851 TPATPTTPTGQQPTTPQT---PQPTSQPQPTPPNSMPPYLPRTQAAGP---------VSQ 1898
            +P+ PT P    P  P     P P   P P PP    P+   T+   P         V+ 
Sbjct: 205  SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1899 GKAAGQVTPPTPPQTAQPPLPG------------------PPPAAVEMA-MQIQRAAETQ 1939
                 + T  +PP++   P                     PPP  V  + + +Q A E  
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPS--GHLE---PGMGPTGMQQQPP 1994
            R+       + P +  +PP   + P     P     P   G L+   P     G  Q   
Sbjct: 325  RKEEGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1995 WSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQP-GLGQVGISPLKPGTVSQQALQN 2053
              + G P P      +P PA   +     PL  A  P    Q    P    T + ++   
Sbjct: 384  DERAGTPPPAP---PLPPPAP-PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSP 439

Query: 2054 LLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI-----PGQPGMPQ 2108
             L+   +P SP        +   +P  +     + AA    S  +       PG    PQ
Sbjct: 440  ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQ 499

Query: 2109 GQPGLQPPTMPGQQGVHSNPA 2129
             + G + P +P ++ + S PA
Sbjct: 500  SKEGKKGPRLPEKETLLSLPA 520



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 44/226 (19%), Positives = 74/226 (32%), Gaps = 31/226 (13%)

Query: 1841 VGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGK 1900
            +GQ Q        TP       P  P  P P + P P P   +PP  P    A   +   
Sbjct: 376  LGQSQSQADERAGTP-------PPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPP 427

Query: 1901 AAGQVTP--PTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIF-------QRP 1951
            A    TP   +P    +P  P P   A    +  +  ++ ++    +  +        R 
Sbjct: 428  AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 1952 IQHQM-PPMTPMAPMGMNPP-----------PMTRGPSGHLEPGMGPTGMQQQPPWSQGG 1999
            + H+  P + P +  G   P           P    P G  E  +G + + +        
Sbjct: 488  LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLT 547

Query: 2000 LPQPQQLQSGMPRPAMMSVAQ--HGQPLNMAPQPGLGQVGISPLKP 2043
            LP    +    P P++  +      +  + A +     +G  P KP
Sbjct: 548  LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP 593



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 56/228 (24%), Positives = 77/228 (33%), Gaps = 41/228 (17%)

Query: 1848 PSPTPATPTTPTGQQ----PTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            P  T   PTT    +    P  P  P+ T +P   P  ++ P  P     GP +  KA  
Sbjct: 620  PQSTTLLPTTSLQPKAMLGPAIP--PKATPEPAIPPKATLWPATPPKATLGPATPLKATS 677

Query: 1904 QVTPP----TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
              T P    + P  A      P   +  MA +    A    + A  ++            
Sbjct: 678  GPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV-----------S 726

Query: 1960 TPMAPMGM-NPPPMTRGPS----------GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQS 2008
            TP    G  +P   TR P+              PG G      +P   Q  L   +++  
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSL--SREVAV 784

Query: 2009 GMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLR 2056
             MP  A    A  G+P+ +   PGL      P KP   S Q    LLR
Sbjct: 785  VMPTLARGGAAGPGEPVEVKEPPGL------PAKP-PASAQPTDELLR 825


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 88/336 (26%), Positives = 126/336 (37%), Gaps = 39/336 (11%)

Query: 673 PNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ-SGLNQFGQMSMAQPPIVPRQTP 731
           P  G P P   S  P P P ++    P  M P   P    L+    +S    P  P   P
Sbjct: 157 PPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216

Query: 732 PLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPV 791
           P      LA P    PP    P    P++    +    FP  G+      +A +  QA  
Sbjct: 217 PAPPLAFLAPP----PPPVPAPAPPAPASP-HTVGTRLFPPGGVTKWKSDVALNGRQAEA 271

Query: 792 SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP--PSI 849
           ++A       P  SP  P GS          P P  H   P       PTP  T   P  
Sbjct: 272 TRAS------PPRSPAEPKGSALG-------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318

Query: 850 GAQQPP------ATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA 903
            AQ+ P          P+ +P PP+    P SQ     P + P P     P +++ + PA
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVY---PDRAPEP---DCPGELKATAPA 372

Query: 904 APSADQPQQQPRSQQST---AASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPS--TS 958
           +P   Q Q Q   +  T   A  +P P  PL PP P  P + P +    + ++PP+  T 
Sbjct: 373 SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTK 432

Query: 959 STEVNSQAIAEK-QPSQEVKMEAKMEVDQPEPADTQ 993
           + + +S A+  K  P       +   VD  +P+  +
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 55/216 (25%), Positives = 76/216 (35%), Gaps = 20/216 (9%)

Query: 810  PGSQGSHIHCPQLPQ---PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTP 866
            PG  G  +  P  P    P   Q+   P P  +P P  +PPS     PP   +  P P P
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEP-PGGSPLP--SPPSTAPPPPPL--LLEPPPPP 184

Query: 867  PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPT 926
               PP P       PP    +P     P  + P+ P A  A  P   P       AS  T
Sbjct: 185  SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244

Query: 927  PTAPLLPPQPATPLSQPAVSIEGQVSN----PPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
                L PP   T      V++ G+ +      P  S  E    A+    P   +      
Sbjct: 245  VGTRLFPPGGVTKWKSD-VALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTFPRSF 302

Query: 983  EVDQPEPADTQPEDISESKVEDCKMESTETEERSTE 1018
            +V  P P  T    + E++      E+   EE +T+
Sbjct: 303  KVPPPTPVRTSSIPVQEAQ------EAPRKEEGATK 332



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 58/277 (20%), Positives = 96/277 (34%), Gaps = 29/277 (10%)

Query: 704 PRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQ 763
           P + PQS   + G       P +P +   L    +   PG     +G     +  +    
Sbjct: 494 PTVAPQSKEGKKG-------PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546

Query: 764 FLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLP 823
            LP   +  Q     ++    +  +A +S A    +   + S  +PP         P+L 
Sbjct: 547 TLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS--LPPK--------PRLE 596

Query: 824 QPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPR 883
              + +N         P   + PP       P T++       PA+PP    +   PP  
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQ-STTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655

Query: 884 QT--PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
                TPP   L         + P+         +  STA ++PT T+ L+  + + P  
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKM 978
           QP      +VS P         SQA  E  PS+  ++
Sbjct: 716 QPEKPASQEVSTP---------SQARGEGSPSEATRL 743



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 73/318 (22%), Positives = 101/318 (31%), Gaps = 53/318 (16%)

Query: 1848 PSPTPATPT--------TPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899
            P P P  P         +P    P+T   P P     P PP+  PP  P  +A  P    
Sbjct: 144  PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203

Query: 1900 KAAGQVT-----PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ--------RQMAHVQ 1946
             +    T     PP PP     P P P PA    A        T+        +  + V 
Sbjct: 204  SSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVA 263

Query: 1947 IFQRPIQ--HQMPPMTPMAP----MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
            +  R  +     PP +P  P    +G NP P    P     P   P      P       
Sbjct: 264  LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323

Query: 2001 PQPQQ-----LQSGMPRPAMMSVAQHGQPL-NMAPQPGLGQVGISPLKPGTVSQQALQNL 2054
            P+ ++       S +P P    +    Q   + AP+P           PG +   A    
Sbjct: 324  PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC---------PGELKATA---- 370

Query: 2055 LRTLRSPSSP-LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGL 2113
                  P+SP L Q Q  +   A     A  +   A       P   P  P +P  Q   
Sbjct: 371  ------PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 2114 QPPTMPGQQGVHSNPAMQ 2131
             PP    +    S+PA++
Sbjct: 425  HPPAGFTKTPKSSSPALK 442



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 83/340 (24%), Positives = 114/340 (33%), Gaps = 72/340 (21%)

Query: 1837 RTGVVGQQQGLPSPTPATPTTPTGQQPTTPQ--TPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
            R G  GQ   +P P P       G  P  PQ  +  P   P P+PP++ PP  P      
Sbjct: 129  RPGQYGQDLLIPPPPP-------GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL---- 177

Query: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH 1954
                      + PP PP  A      PPP  V        A      ++   I   P   
Sbjct: 178  ----------LEPPPPPSMA------PPPPPV------LEALSPPHTLSSPSIPTPP--D 213

Query: 1955 QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP-----WSQGGLPQPQQLQSG 2009
             +PP  P+A +   PPP+   P+          G +  PP     W        +Q ++ 
Sbjct: 214  FIPPAPPLAFLAPPPPPVP-APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQ 2069
               P        G  L   P+P L       + P T            +R+ S P+Q+ Q
Sbjct: 273  RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT-----------PVRTSSIPVQEAQ 321

Query: 2070 VLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQ--PGLQP-PTMPGQQGVHS 2126
                        A   ++ A K A S     P     P  Q  P   P P  PG+    +
Sbjct: 322  E-----------APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA-T 369

Query: 2127 NPAMQNMNPMQAGV-QRAGLPQQQPQQQLQPPMGGMSPQA 2165
             PA   +   Q+   +RAG P   P   L PP   + P A
Sbjct: 370  APASPRLGQSQSQADERAGTP--PPAPPLPPPAPPLPPPA 407



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 111/514 (21%), Positives = 183/514 (35%), Gaps = 105/514 (20%)

Query: 653  QKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT-PQSG 711
            Q Q+     AG  P    P P +  P P +    P P P +   + P     +   P +G
Sbjct: 378  QSQSQADERAGTPP----PAPPLPPPAPPL----PPPAPPLPPAAPPLPCAQKAAHPPAG 429

Query: 712  LNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQ-GQFL----P 766
              +  + S   P + P+  PP   +   + P     P     +M++  N+   +L     
Sbjct: 430  FTKTPKSS--SPALKPKPNPPSPENTASSAPVDWRDPS----QMEKLRNELAAYLCGSRR 483

Query: 767  QTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNS--PIMPPGSQGSHIHCPQLPQ 824
            + +F S     T  P +    + P    + +  S P     P +P  S G          
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 825  PALHQNSPSPVPSRTPTP--HHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALH--- 879
            P+L   S   +P  +PTP        + A+   A    A  P+  ++PP P+ +      
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK-PSIGSLPPKPRLEGGRICE 602

Query: 880  ----------------PPPRQTPTPPTTQLPQ-QVQPSLPAAPSADQPQQQPRSQQSTAA 922
                            PP   T  P T+  P+  + P++P       P+  P       A
Sbjct: 603  NGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP-------PKATPEPAIPPKA 655

Query: 923  SVPTPTAPLLPPQPATPL------SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ--PSQ 974
            ++   T P     PATPL      + P  +  G      +T+     SQ +AEK   P+ 
Sbjct: 656  TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 975  EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSA 1034
            + +  A  EV  P          S+++ E    E+T    +               S++A
Sbjct: 716  QPEKPASQEVSTP----------SQARGEGSPSEATRLPTQGAR------------SSAA 753

Query: 1035 TQSSPAPGQSKKK-IFKPEELRQAL-------MPTL---------EALYRQDPESLPFRQ 1077
                 +PG  +   ++KP   + +L       MPTL         E +  ++P  LP + 
Sbjct: 754  FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813

Query: 1078 PVDPQ----LLGIPDYFDIVK--SPMDLSTIKRK 1105
            P   Q    LL  P   ++V+  SPM L    R+
Sbjct: 814  PASAQPTDELLRHPVTGEVVERGSPMALLLAARQ 847



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 70/321 (21%), Positives = 107/321 (33%), Gaps = 47/321 (14%)

Query: 1851 TPATPTTPTGQQPTTPQT---PQPTSQPQPTPPNSMPPYLPRTQAAGP---------VSQ 1898
            +P+ PT P    P  P     P P   P P PP    P+   T+   P         V+ 
Sbjct: 205  SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1899 GKAAGQVTPPTPPQTAQPPLPG------------------PPPAAVEMA-MQIQRAAETQ 1939
                 + T  +PP++   P                     PPP  V  + + +Q A E  
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPS--GHLE---PGMGPTGMQQQPP 1994
            R+       + P +  +PP   + P     P     P   G L+   P     G  Q   
Sbjct: 325  RKEEGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1995 WSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQP-GLGQVGISPLKPGTVSQQALQN 2053
              + G P P      +P PA   +     PL  A  P    Q    P    T + ++   
Sbjct: 384  DERAGTPPPAP---PLPPPAP-PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSP 439

Query: 2054 LLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI-----PGQPGMPQ 2108
             L+   +P SP        +   +P  +     + AA    S  +       PG    PQ
Sbjct: 440  ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQ 499

Query: 2109 GQPGLQPPTMPGQQGVHSNPA 2129
             + G + P +P ++ + S PA
Sbjct: 500  SKEGKKGPRLPEKETLLSLPA 520



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 44/226 (19%), Positives = 74/226 (32%), Gaps = 31/226 (13%)

Query: 1841 VGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGK 1900
            +GQ Q        TP       P  P  P P + P P P   +PP  P    A   +   
Sbjct: 376  LGQSQSQADERAGTP-------PPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPP 427

Query: 1901 AAGQVTP--PTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIF-------QRP 1951
            A    TP   +P    +P  P P   A    +  +  ++ ++    +  +        R 
Sbjct: 428  AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 1952 IQHQM-PPMTPMAPMGMNPP-----------PMTRGPSGHLEPGMGPTGMQQQPPWSQGG 1999
            + H+  P + P +  G   P           P    P G  E  +G + + +        
Sbjct: 488  LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLT 547

Query: 2000 LPQPQQLQSGMPRPAMMSVAQ--HGQPLNMAPQPGLGQVGISPLKP 2043
            LP    +    P P++  +      +  + A +     +G  P KP
Sbjct: 548  LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP 593



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 56/228 (24%), Positives = 77/228 (33%), Gaps = 41/228 (17%)

Query: 1848 PSPTPATPTTPTGQQ----PTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            P  T   PTT    +    P  P  P+ T +P   P  ++ P  P     GP +  KA  
Sbjct: 620  PQSTTLLPTTSLQPKAMLGPAIP--PKATPEPAIPPKATLWPATPPKATLGPATPLKATS 677

Query: 1904 QVTPP----TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
              T P    + P  A      P   +  MA +    A    + A  ++            
Sbjct: 678  GPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV-----------S 726

Query: 1960 TPMAPMGM-NPPPMTRGPS----------GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQS 2008
            TP    G  +P   TR P+              PG G      +P   Q  L   +++  
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSL--SREVAV 784

Query: 2009 GMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLR 2056
             MP  A    A  G+P+ +   PGL      P KP   S Q    LLR
Sbjct: 785  VMPTLARGGAAGPGEPVEVKEPPGL------PAKP-PASAQPTDELLR 825


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 88/336 (26%), Positives = 126/336 (37%), Gaps = 39/336 (11%)

Query: 673 PNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ-SGLNQFGQMSMAQPPIVPRQTP 731
           P  G P P   S  P P P ++    P  M P   P    L+    +S    P  P   P
Sbjct: 157 PPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216

Query: 732 PLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPV 791
           P      LA P    PP    P    P++    +    FP  G+      +A +  QA  
Sbjct: 217 PAPPLAFLAPP----PPPVPAPAPPAPASP-HTVGTRLFPPGGVTKWKSDVALNGRQAEA 271

Query: 792 SQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP--PSI 849
           ++A       P  SP  P GS          P P  H   P       PTP  T   P  
Sbjct: 272 TRAS------PPRSPAEPKGSALG-------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318

Query: 850 GAQQPP------ATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPA 903
            AQ+ P          P+ +P PP+    P SQ     P + P P     P +++ + PA
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVY---PDRAPEP---DCPGELKATAPA 372

Query: 904 APSADQPQQQPRSQQST---AASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPS--TS 958
           +P   Q Q Q   +  T   A  +P P  PL PP P  P + P +    + ++PP+  T 
Sbjct: 373 SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTK 432

Query: 959 STEVNSQAIAEK-QPSQEVKMEAKMEVDQPEPADTQ 993
           + + +S A+  K  P       +   VD  +P+  +
Sbjct: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 55/216 (25%), Positives = 76/216 (35%), Gaps = 20/216 (9%)

Query: 810  PGSQGSHIHCPQLPQ---PALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTP 866
            PG  G  +  P  P    P   Q+   P P  +P P  +PPS     PP   +  P P P
Sbjct: 130  PGQYGQDLLIPPPPPGPAPGPPQDISEP-PGGSPLP--SPPSTAPPPPPL--LLEPPPPP 184

Query: 867  PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPT 926
               PP P       PP    +P     P  + P+ P A  A  P   P       AS  T
Sbjct: 185  SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244

Query: 927  PTAPLLPPQPATPLSQPAVSIEGQVSN----PPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
                L PP   T      V++ G+ +      P  S  E    A+    P   +      
Sbjct: 245  VGTRLFPPGGVTKWKSD-VALNGRQAEATRASPPRSPAEPKGSALG-PNPEPHLTFPRSF 302

Query: 983  EVDQPEPADTQPEDISESKVEDCKMESTETEERSTE 1018
            +V  P P  T    + E++      E+   EE +T+
Sbjct: 303  KVPPPTPVRTSSIPVQEAQ------EAPRKEEGATK 332



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 58/277 (20%), Positives = 96/277 (34%), Gaps = 29/277 (10%)

Query: 704 PRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQ 763
           P + PQS   + G       P +P +   L    +   PG     +G     +  +    
Sbjct: 494 PTVAPQSKEGKKG-------PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546

Query: 764 FLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLP 823
            LP   +  Q     ++    +  +A +S A    +   + S  +PP         P+L 
Sbjct: 547 TLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS--LPPK--------PRLE 596

Query: 824 QPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPR 883
              + +N         P   + PP       P T++       PA+PP    +   PP  
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQ-STTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655

Query: 884 QT--PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
                TPP   L         + P+         +  STA ++PT T+ L+  + + P  
Sbjct: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKM 978
           QP      +VS P         SQA  E  PS+  ++
Sbjct: 716 QPEKPASQEVSTP---------SQARGEGSPSEATRL 743



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 73/318 (22%), Positives = 101/318 (31%), Gaps = 53/318 (16%)

Query: 1848 PSPTPATPT--------TPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQG 1899
            P P P  P         +P    P+T   P P     P PP+  PP  P  +A  P    
Sbjct: 144  PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203

Query: 1900 KAAGQVT-----PPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQ--------RQMAHVQ 1946
             +    T     PP PP     P P P PA    A        T+        +  + V 
Sbjct: 204  SSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVA 263

Query: 1947 IFQRPIQ--HQMPPMTPMAP----MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
            +  R  +     PP +P  P    +G NP P    P     P   P      P       
Sbjct: 264  LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323

Query: 2001 PQPQQ-----LQSGMPRPAMMSVAQHGQPL-NMAPQPGLGQVGISPLKPGTVSQQALQNL 2054
            P+ ++       S +P P    +    Q   + AP+P           PG +   A    
Sbjct: 324  PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC---------PGELKATA---- 370

Query: 2055 LRTLRSPSSP-LQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGL 2113
                  P+SP L Q Q  +   A     A  +   A       P   P  P +P  Q   
Sbjct: 371  ------PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 2114 QPPTMPGQQGVHSNPAMQ 2131
             PP    +    S+PA++
Sbjct: 425  HPPAGFTKTPKSSSPALK 442



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 83/340 (24%), Positives = 114/340 (33%), Gaps = 72/340 (21%)

Query: 1837 RTGVVGQQQGLPSPTPATPTTPTGQQPTTPQ--TPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
            R G  GQ   +P P P       G  P  PQ  +  P   P P+PP++ PP  P      
Sbjct: 129  RPGQYGQDLLIPPPPP-------GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL---- 177

Query: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH 1954
                      + PP PP  A      PPP  V        A      ++   I   P   
Sbjct: 178  ----------LEPPPPPSMA------PPPPPV------LEALSPPHTLSSPSIPTPP--D 213

Query: 1955 QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP-----WSQGGLPQPQQLQSG 2009
             +PP  P+A +   PPP+   P+          G +  PP     W        +Q ++ 
Sbjct: 214  FIPPAPPLAFLAPPPPPVP-APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQ 2069
               P        G  L   P+P L       + P T            +R+ S P+Q+ Q
Sbjct: 273  RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT-----------PVRTSSIPVQEAQ 321

Query: 2070 VLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQ--PGLQP-PTMPGQQGVHS 2126
                        A   ++ A K A S     P     P  Q  P   P P  PG+    +
Sbjct: 322  E-----------APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA-T 369

Query: 2127 NPAMQNMNPMQAGV-QRAGLPQQQPQQQLQPPMGGMSPQA 2165
             PA   +   Q+   +RAG P   P   L PP   + P A
Sbjct: 370  APASPRLGQSQSQADERAGTP--PPAPPLPPPAPPLPPPA 407



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 111/514 (21%), Positives = 183/514 (35%), Gaps = 105/514 (20%)

Query: 653  QKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRIT-PQSG 711
            Q Q+     AG  P    P P +  P P +    P P P +   + P     +   P +G
Sbjct: 378  QSQSQADERAGTPP----PAPPLPPPAPPL----PPPAPPLPPAAPPLPCAQKAAHPPAG 429

Query: 712  LNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQ-GQFL----P 766
              +  + S   P + P+  PP   +   + P     P     +M++  N+   +L     
Sbjct: 430  FTKTPKSS--SPALKPKPNPPSPENTASSAPVDWRDPS----QMEKLRNELAAYLCGSRR 483

Query: 767  QTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNS--PIMPPGSQGSHIHCPQLPQ 824
            + +F S     T  P +    + P    + +  S P     P +P  S G          
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 825  PALHQNSPSPVPSRTPTP--HHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALH--- 879
            P+L   S   +P  +PTP        + A+   A    A  P+  ++PP P+ +      
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK-PSIGSLPPKPRLEGGRICE 602

Query: 880  ----------------PPPRQTPTPPTTQLPQ-QVQPSLPAAPSADQPQQQPRSQQSTAA 922
                            PP   T  P T+  P+  + P++P       P+  P       A
Sbjct: 603  NGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP-------PKATPEPAIPPKA 655

Query: 923  SVPTPTAPLLPPQPATPL------SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ--PSQ 974
            ++   T P     PATPL      + P  +  G      +T+     SQ +AEK   P+ 
Sbjct: 656  TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715

Query: 975  EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSA 1034
            + +  A  EV  P          S+++ E    E+T    +               S++A
Sbjct: 716  QPEKPASQEVSTP----------SQARGEGSPSEATRLPTQGAR------------SSAA 753

Query: 1035 TQSSPAPGQSKKK-IFKPEELRQAL-------MPTL---------EALYRQDPESLPFRQ 1077
                 +PG  +   ++KP   + +L       MPTL         E +  ++P  LP + 
Sbjct: 754  FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813

Query: 1078 PVDPQ----LLGIPDYFDIVK--SPMDLSTIKRK 1105
            P   Q    LL  P   ++V+  SPM L    R+
Sbjct: 814  PASAQPTDELLRHPVTGEVVERGSPMALLLAARQ 847



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 70/321 (21%), Positives = 107/321 (33%), Gaps = 47/321 (14%)

Query: 1851 TPATPTTPTGQQPTTPQT---PQPTSQPQPTPPNSMPPYLPRTQAAGP---------VSQ 1898
            +P+ PT P    P  P     P P   P P PP    P+   T+   P         V+ 
Sbjct: 205  SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVAL 264

Query: 1899 GKAAGQVTPPTPPQTAQPPLPG------------------PPPAAVEMA-MQIQRAAETQ 1939
                 + T  +PP++   P                     PPP  V  + + +Q A E  
Sbjct: 265  NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324

Query: 1940 RQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPS--GHLE---PGMGPTGMQQQPP 1994
            R+       + P +  +PP   + P     P     P   G L+   P     G  Q   
Sbjct: 325  RKEEGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383

Query: 1995 WSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQP-GLGQVGISPLKPGTVSQQALQN 2053
              + G P P      +P PA   +     PL  A  P    Q    P    T + ++   
Sbjct: 384  DERAGTPPPAP---PLPPPAP-PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSP 439

Query: 2054 LLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPI-----PGQPGMPQ 2108
             L+   +P SP        +   +P  +     + AA    S  +       PG    PQ
Sbjct: 440  ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQ 499

Query: 2109 GQPGLQPPTMPGQQGVHSNPA 2129
             + G + P +P ++ + S PA
Sbjct: 500  SKEGKKGPRLPEKETLLSLPA 520



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 44/226 (19%), Positives = 74/226 (32%), Gaps = 31/226 (13%)

Query: 1841 VGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGK 1900
            +GQ Q        TP       P  P  P P + P P P   +PP  P    A   +   
Sbjct: 376  LGQSQSQADERAGTP-------PPAPPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPP 427

Query: 1901 AAGQVTP--PTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIF-------QRP 1951
            A    TP   +P    +P  P P   A    +  +  ++ ++    +  +        R 
Sbjct: 428  AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRF 487

Query: 1952 IQHQM-PPMTPMAPMGMNPP-----------PMTRGPSGHLEPGMGPTGMQQQPPWSQGG 1999
            + H+  P + P +  G   P           P    P G  E  +G + + +        
Sbjct: 488  LSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLT 547

Query: 2000 LPQPQQLQSGMPRPAMMSVAQ--HGQPLNMAPQPGLGQVGISPLKP 2043
            LP    +    P P++  +      +  + A +     +G  P KP
Sbjct: 548  LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP 593



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 56/228 (24%), Positives = 77/228 (33%), Gaps = 41/228 (17%)

Query: 1848 PSPTPATPTTPTGQQ----PTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            P  T   PTT    +    P  P  P+ T +P   P  ++ P  P     GP +  KA  
Sbjct: 620  PQSTTLLPTTSLQPKAMLGPAIP--PKATPEPAIPPKATLWPATPPKATLGPATPLKATS 677

Query: 1904 QVTPP----TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
              T P    + P  A      P   +  MA +    A    + A  ++            
Sbjct: 678  GPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV-----------S 726

Query: 1960 TPMAPMGM-NPPPMTRGPS----------GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQS 2008
            TP    G  +P   TR P+              PG G      +P   Q  L   +++  
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSL--SREVAV 784

Query: 2009 GMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLR 2056
             MP  A    A  G+P+ +   PGL      P KP   S Q    LLR
Sbjct: 785  VMPTLARGGAAGPGEPVEVKEPPGL------PAKP-PASAQPTDELLR 825


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 89/318 (27%), Positives = 116/318 (36%), Gaps = 46/318 (14%)

Query: 653 QKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGL 712
           Q Q   P  A     +  P     QP PG+ S+       ++ G  P+     I  Q  L
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS----PEKIVLGQPPSATPTAILTQDSL 696

Query: 713 NQFGQMSMAQPPIVPRQTPPLQHHGQL---AQPGALNPP--------MGYGPRMQQPSNQ 761
             F     +Q P+   + P L     +   A P A +P          G GP  Q P +Q
Sbjct: 697 QMFLPQERSQQPL-SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGP--QAPDSQ 753

Query: 762 GQFLPQTQFPS----QGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHI 817
               P  Q P+    +G   ++ P  P   QAP+  +    S  P   P  PP    S  
Sbjct: 754 ASPAPAPQIPAAAPLKGPGPSSSPSLPH--QAPLGDSPHLPSPHPTRPPSRPPSRPQSVS 811

Query: 818 HCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQ 876
             P   +P LH   P   P   P        +G   PP  + PAP  P PP  P  PQSQ
Sbjct: 812 RPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLGV--PPPASNPAPTAPGPPQPPLRPQSQ 867

Query: 877 ALHPPPRQTPTPPTTQLP-----------QQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
                P + P PP   LP            +    LPA   +D   Q P SQ    +  P
Sbjct: 868 -----PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP 922

Query: 926 TPTAPLLPPQPATPLSQP 943
            PT  L+ P+PA P   P
Sbjct: 923 PPTLHLV-PEPAAPPPPP 939



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 95/390 (24%), Positives = 138/390 (35%), Gaps = 38/390 (9%)

Query: 661  AAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSM 720
            AAG +P    P P  G     +     LP  ++   + P+ ++   TP +   +   +  
Sbjct: 562  AAGSLPTQSQPAP-AGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLT 620

Query: 721  AQPP--IVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVT 778
             QP     P  + PL     L QP A  PP       Q P+ Q    PQ   P     + 
Sbjct: 621  VQPAPQAPPAVSTPLPLG--LQQPQAQQPP-------QAPTPQAAAPPQATTPQPSPGLA 671

Query: 779  NIPLAPSSGQAPVSQ--AQMSSSSC----PVNSPIMPPGSQGSHIHCPQLPQPALHQNSP 832
            + P     GQ P +   A ++  S     P      P  ++G H+  P     ++  ++P
Sbjct: 672  SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA----SVIVSAP 727

Query: 833  SPVPSRTP-TPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTT 891
             P     P TP      +G Q P +   PAP P  PA  P        P P  +P+ P  
Sbjct: 728  PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAP-----LKGPGPSSSPSLPH- 781

Query: 892  QLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQV 951
            Q P    P LP+      P + P   QS +     P     PP  A P       I+ Q+
Sbjct: 782  QAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQL 841

Query: 952  SNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTE 1011
              PP  S    N    A   P   ++ +++       PA   P   + S V      S+E
Sbjct: 842  GVPPPAS----NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAV----ASSSE 893

Query: 1012 TEERSTELKTEIKEEEDQPSTSATQSSPAP 1041
            T  R     T    +   P +     SP P
Sbjct: 894  TSSR-LPAPTPSDFQLQFPPSQGPHKSPTP 922



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 87/335 (25%), Positives = 119/335 (35%), Gaps = 63/335 (18%)

Query: 655  QNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGP-LPDPSMIRGSVPNQMMPRITPQSGLN 713
            Q  LP      P+S   GP++  P   + S  P   DP+          +    P S   
Sbjct: 697  QMFLPQERSQQPLSAE-GPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS--- 752

Query: 714  QFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPS 772
               Q S A  P +P   P L+  G  + P   +  P+G  P +  P       P ++ PS
Sbjct: 753  ---QASPAPAPQIPAAAP-LKGPGPSSSPSLPHQAPLGDSPHLPSPHPTR---PPSRPPS 805

Query: 773  QGMNVTNIPLAPSSGQAPVSQAQMSSSSCPV--NSPIMPPGSQGSHIHCPQLPQPALHQN 830
            +  +V+  P  P     P  QA  +     V  N   +PP +       P  PQP L   
Sbjct: 806  RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865

Query: 831  SPSPVPSRTPTPHHTPPS----IGAQQPPATTIPAPVPT------------------PPA 868
            S  P     P PH  P S    + +    ++ +PAP P+                  PP 
Sbjct: 866  SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT 925

Query: 869  MPPGPQSQALHPPPRQTPTPPTTQLPQQVQP--------SLPA----------APSADQP 910
            +   P+  A  PPP +T    TT  P   QP         +P+          AP+A Q 
Sbjct: 926  LHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQT 985

Query: 911  QQQPRSQQSTAASV--------PTPTAPLLPPQPA 937
                    S AASV         TPTAP   P PA
Sbjct: 986  STSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 123/538 (22%), Positives = 181/538 (33%), Gaps = 103/538 (19%)

Query: 640  IQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQP---QPGMTSNGPLPDPSMIRG 696
            IQK L     T L   ++   A      S   G   GQP    PG+ S+  +P P++I  
Sbjct: 289  IQKNLSAAVATTLNGNSVFGGAGA---ASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILH 345

Query: 697  SVPNQMMPR-----------ITPQSGLNQFGQMSM-AQPPIVPRQ--------------- 729
              P  + P+           +TP+        +++  +P  +P+Q               
Sbjct: 346  RTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405

Query: 730  --------------------TPPLQHHGQL--AQPGALNPPMGYG----------PRMQQ 757
                                 PP    G      PGAL+ PM             P    
Sbjct: 406  GQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHM 465

Query: 758  PSNQGQFL----PQTQFPSQ-GMNVTNIPLAPSSGQAPVSQAQMSSSSCPVN-------- 804
               Q QFL    P  Q P Q      N+     +  AP +  Q+ ++    N        
Sbjct: 466  LPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLS 525

Query: 805  -SPIMPP--GSQGSHIHCP---QLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATT 858
              P++ P  G+  +HI      Q+ QPAL Q   S      PT     P+     P ATT
Sbjct: 526  LGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA----GPAATT 581

Query: 859  IPAPVPTPP---AMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQP--QQQ 913
            +   V  PP   AM   P        P          L  Q  P  P A S   P   QQ
Sbjct: 582  VLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQ 641

Query: 914  PRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQ---VSNPPSTSSTEVNSQAIAEK 970
            P++QQ   A  PTP A   PPQ  TP   P ++   +   +  PPS + T + +Q   + 
Sbjct: 642  PQAQQPPQA--PTPQA-AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQM 698

Query: 971  QPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETE-ERSTELKTEIKEEEDQ 1029
               QE    ++  +    P  + P  +  S     +  +  T   +   L  +  + +  
Sbjct: 699  FLPQE---RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS 755

Query: 1030 PSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP 1087
            P+ +    + AP +       P    QA +     L    P   P R P  PQ +  P
Sbjct: 756  PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP 813



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 129/536 (24%), Positives = 181/536 (33%), Gaps = 113/536 (21%)

Query: 1847 LPSPTPATPTTPTGQ--QPTTPQT-------PQPTSQPQPTPPNSMPPYLPRTQA----- 1892
            LP    A P    GQ      P T       P  T+Q    P +  P   P + A     
Sbjct: 482  LPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHI 541

Query: 1893 --AGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR 1950
              A P+  G+ A    P +    + P    P PA       +Q        +A +     
Sbjct: 542  LSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDG 601

Query: 1951 PIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMG---PTGMQQ----QPPWSQGGLPQ- 2002
             +Q    P TP A  G   P +T  P+    P +    P G+QQ    QPP  Q   PQ 
Sbjct: 602  LVQ----PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP--QAPTPQA 655

Query: 2003 --PQQLQSGMPRPAMMSVAQH---GQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRT 2057
              P Q  +  P P + S  +    GQP +  P                ++Q +LQ  L  
Sbjct: 656  AAPPQATTPQPSPGLASSPEKIVLGQPPSATPT-------------AILTQDSLQMFLPQ 702

Query: 2058 LRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPT 2117
             RS       QQ LS    +  + A+ I        ++ P      P  P  +     P 
Sbjct: 703  ERS-------QQPLSAEGPHLSVPASVI-------VSAPPPAQDPAPATPVAKGAGLGPQ 748

Query: 2118 MPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPS 2177
             P  Q   ++PA     P  A ++  G P   P    Q P+G  SP        H   P 
Sbjct: 749  APDSQ---ASPAPAPQIPAAAPLKGPG-PSSSPSLPHQAPLGD-SP--------HLPSPH 795

Query: 2178 QFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQG 2237
              R   R     Q   +  + P + P                PP Q       +  +Q  
Sbjct: 796  PTRPPSRPPSRPQSVSRPPSEPPLHP---------------CPPPQAPPTLPGIFVIQN- 839

Query: 2238 NMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQ 2297
               Q+G  P A  +    +     Q  L+ Q   P  P P +P  H+ P+   S      
Sbjct: 840  ---QLGVPPPA--SNPAPTAPGPPQPPLRPQSQPPEGPLPPAP--HLPPSSTSSA----- 887

Query: 2298 QIPNSLSNQVRSPQPVPS----PRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHP 2349
             + +S     R P P PS      P SQ PH SP+P     P   H+ P+ ++P P
Sbjct: 888  -VASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP-----PPTLHLVPEPAAPPP 937



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 136/610 (22%), Positives = 189/610 (30%), Gaps = 127/610 (20%)

Query: 1849 SPTPATPTTPTGQQPTT--PQTPQPTSQPQPT-----PPNSMP--PYLPRT---QAAGPV 1896
            +PTP  P  P G  P      TP+P +    T      P ++P  P  P+     AAG  
Sbjct: 347  TPTPIQPK-PAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405

Query: 1897 SQGKAAGQVTPPT--------PPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIF 1948
             Q         P         PP T     P  PP A+   M +        Q + + I 
Sbjct: 406  GQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLL----NQGSSIVI- 460

Query: 1949 QRPIQHQMPP----MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL-PQP 2003
              P QH +P     + P AP    P  ++  P+      +G   +    P + G L   P
Sbjct: 461  --PAQHMLPGQNQFLLPGAPAVQLPQQLSALPAN-----VGGQILAAAAPHTGGQLIANP 513

Query: 2004 QQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSS 2063
                  +  P  +          +AP  G     I    P  V Q AL  +  +L + S 
Sbjct: 514  ILTNQNLAGPLSLGPV-------LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSL 566

Query: 2064 PLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQG 2123
            P Q Q   +   A   L    +   A    N+    +  QP  P    G   P +  Q  
Sbjct: 567  PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV--QPATPAAATGEAAPVLTVQPA 624

Query: 2124 VHSNPAM-----------QNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNH 2172
              + PA+           Q   P QA   +A  P Q    Q  P +   SP+   +    
Sbjct: 625  PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLAS-SPEKIVLGQPP 683

Query: 2173 NTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQF--------QQP-------QGV 2217
            +  P+        Q  + Q++ Q      GP ++             Q P       +G 
Sbjct: 684  SATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGA 743

Query: 2218 GYPPQQQQRMQHHMQQMQQGNMGQIGQLPQAL-----GAEAGASLQAYQQRLLQQQMGSP 2272
            G  PQ             Q +     Q+P A      G  +  SL           + SP
Sbjct: 744  GLGPQAPD---------SQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSP 794

Query: 2273 ---------------VQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSP- 2316
                           V   P  P  H  P     P L G  +   + NQ+  P P  +P 
Sbjct: 795  HPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFV---IQNQLGVPPPASNPA 851

Query: 2317 -----------RPQSQPP--------HSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQAN 2357
                       RPQSQPP        H  PS       S    S +  +P P     Q  
Sbjct: 852  PTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF- 910

Query: 2358 PMEQGHFASP 2367
            P  QG   SP
Sbjct: 911  PPSQGPHKSP 920



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 77/328 (23%), Positives = 105/328 (32%), Gaps = 80/328 (24%)

Query: 1834 SMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQT-PQPTSQP--QPTPPNSMPPYLPRT 1890
            S+     +G    LPSP P   T P  + P+ PQ+  +P S+P   P PP   PP LP  
Sbjct: 778  SLPHQAPLGDSPHLPSPHP---TRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI 834

Query: 1891 QAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR 1950
                         Q+  P P     P  PGPP   +    Q                   
Sbjct: 835  FV--------IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ------------------- 867

Query: 1951 PIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGM 2010
            P +  +PP   + P   +    +   +    P   P+  Q Q P SQG    P       
Sbjct: 868  PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP------T 921

Query: 2011 PRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV 2070
            P P +  V +   P    P P   Q+  +P                    P+ P Q + +
Sbjct: 922  PPPTLHLVPEPAAP--PPPPPRTFQMVTTPF-------------------PALP-QPKAL 959

Query: 2071 LSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQ------QGV 2124
            L   H   Q+ +  I Q  A           G P  PQ    L P T P        Q  
Sbjct: 960  LERFH---QVPSGIILQNKA----------GGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006

Query: 2125 HSNPAMQNMNPMQAGVQRAGLPQQQPQQ 2152
               P   +  P  A +   GLP   P +
Sbjct: 1007 SGTPTAPSHAPAPAPMAATGLPPLLPAE 1034



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 80/355 (22%), Positives = 109/355 (30%), Gaps = 71/355 (20%)

Query: 659  PNAAGMVPVSM---NPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQF 715
            P  A  +P +     PGP+     P +    PL D   +    P+   P   P S     
Sbjct: 756  PAPAPQIPAAAPLKGPGPSSS---PSLPHQAPLGDSPHLPS--PHPTRPPSRPPSRPQSV 810

Query: 716  GQMSMAQP--PIVPRQTPPLQH-----HGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQT 768
             +     P  P  P Q PP          QL  P   + P    P   QP  +    PQ+
Sbjct: 811  SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLR----PQS 866

Query: 769  QFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSP----IMPPGSQGSHIHCPQLPQ 824
            Q P +G       L PSS  + V+ +  +SS  P  +P    +  P SQG H      P 
Sbjct: 867  Q-PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKS--PTPP 923

Query: 825  PALH----QNSPSPVPSRT-------------------------------------PTPH 843
            P LH      +P P P RT                                     P   
Sbjct: 924  PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983

Query: 844  HTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQV----QP 899
             T  S+G    PA ++      P   P  P       P   T  PP      +      P
Sbjct: 984  QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP 1043

Query: 900  SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNP 954
            +L  A +A     +P   Q  +        P L P       +     +G V +P
Sbjct: 1044 TLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHP 1098



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 41/166 (24%), Positives = 58/166 (34%), Gaps = 32/166 (19%)

Query: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP 1907
            P P P  P  PTGQ   T   P P +  +   P    P+ PR        +         
Sbjct: 1345 PPPRPPPPPPPTGQMNGTVDHPPPAAPER--KPLGTAPHCPRLPLRKTYRENVGGPGAPE 1402

Query: 1908 PTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHV--QIFQRPIQHQMPPMTPMAPM 1965
             TP   A+   P P PA V+ A      +   R++A V  +++QR ++            
Sbjct: 1403 GTPAGRARGGSPAPLPAKVDEA-----TSGLIRELAAVEDELYQRMLK------------ 1445

Query: 1966 GMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMP 2011
               PPP         EP          P W   GLP  ++ +S  P
Sbjct: 1446 --GPPP---------EPAASAAQGTGDPDWEAPGLPPAKRRKSESP 1480



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 50/188 (26%), Positives = 62/188 (32%), Gaps = 38/188 (20%)

Query: 826  ALHQNSPSPVPSRTPTPHHT-------------PPSIGAQQPPATTIPAPVPTPPAMPPG 872
            +L  +   P+PSR   P  T                 G  +    T   PV  PP  PP 
Sbjct: 1280 SLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPP--PPP 1337

Query: 873  PQSQALHPPPRQT-PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPL 931
               +   PPPR   P PPT Q+   V    PAAP         R    TA     P  P 
Sbjct: 1338 ATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE--------RKPLGTA-----PHCPR 1384

Query: 932  LPPQ---------PATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
            LP +         P  P   PA    G    P      E  S  I E    ++   +  +
Sbjct: 1385 LPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML 1444

Query: 983  EVDQPEPA 990
            +   PEPA
Sbjct: 1445 KGPPPEPA 1452



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 103/480 (21%), Positives = 154/480 (32%), Gaps = 65/480 (13%)

Query: 1967 MNPPPMTRGPSGHLE--------------PGMGPTGMQQQPPWSQGGLPQPQQLQSGMPR 2012
            +NP P    PS  L+               G G  G  Q     Q  L +    +  +  
Sbjct: 61   LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA 120

Query: 2013 PAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQAL---QNLLRTLRSPSSPLQQQQ 2069
             A + +     P       G G  G           QAL      L  L+ P + L  Q 
Sbjct: 121  EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA 180

Query: 2070 VLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQP--------GLQPPTMPGQ 2121
            ++       + L+     +     N   QPIPG  G+P G P        GL P  + GQ
Sbjct: 181  LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ 240

Query: 2122 QGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRD 2181
              +  N     +   Q  V         P + +     G+SPQ   + +  N + +    
Sbjct: 241  PVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKN-LSAAVAT 299

Query: 2182 ILRRQQMMQQQQQQGAGPGIGP-GMANHNQFQQPQGVGYPPQQQ------QRMQHHMQQM 2234
             L    +       GAG    P G  +        G+G  P          R    +Q  
Sbjct: 300  TLNGNSVF-----GGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPK 354

Query: 2235 QQGNM-GQIGQLPQALGAEAGASLQAYQQRLLQQQMGS-PVQPNPMSPQQHMLPNQA-QS 2291
              G +  ++ QL     A AGA+L       +Q + G+ P QP        M   +A Q+
Sbjct: 355  PAGVLPPKLYQLTPKPFAPAGATL------TIQGEPGALPQQPKAPQNLTFMAAGKAGQN 408

Query: 2292 PHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQ---------PSPHHVSP 2342
              L G   P   +N  + P    +     QPP +   P              P+ H +  
Sbjct: 409  VVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPG 468

Query: 2343 QTSSPHPGLVAAQANPMEQGHFASPDQNSMLS--------QLASNPGMANLHGASATDLG 2394
            Q     PG  A Q  P +     +     +L+        QL +NP + N + A    LG
Sbjct: 469  QNQFLLPGAPAVQL-PQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 106/396 (26%), Positives = 150/396 (37%), Gaps = 57/396 (14%)

Query: 657  MLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPL-----PDPSMIRGSVPNQMMPRITPQSG 711
            +LP  +  +P         GQ  P +    PL     P P +    VP  + P + P S 
Sbjct: 709  VLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQ 768

Query: 712  LNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPM-------GYGPRMQQ-PSNQGQ 763
            +    Q+   Q P  P Q  PL        P  + PP+       G  P +   P+    
Sbjct: 769  VGAPAQLKPLQMPQAPLQ--PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVP 826

Query: 764  FLPQTQFPSQGMNVTNI--PLAPSSGQAPVSQAQMSS--------------SSCPVNSPI 807
             +P  Q+ S  + + ++  PL P+S   P+   ++                 + P   P+
Sbjct: 827  PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPL 886

Query: 808  M---PPGSQGSHIH--CPQLP-QP----ALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857
            +   PPG     IH    QLP QP    A  Q +P+ VP   P+PHHT  ++ A  PP  
Sbjct: 887  LAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVP---PSPHHTVQNMRA-TPPQP 942

Query: 858  TIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ 917
             +P P PT P  P  P    L P P   P P  T+ PQ V P  P  P   QP   P   
Sbjct: 943  ALP-PQPTLPPQPVLPPQPTLPPQPVLPPQP--TRPPQPVLPPQPMLP--PQPVLPP--- 994

Query: 918  QSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVK 977
            Q      P P  P LP Q A P + P   I   +   P+  + +V +Q      P   V 
Sbjct: 995  QPALPVRPEPLQPHLPEQ-AAPAATPGSQI---LLGHPAPYAVDVAAQVPTVPVPPAAVL 1050

Query: 978  MEAKMEVDQPEPADTQPEDISESKVEDCKMESTETE 1013
                 EV  P   +  P+  S        ++S  T+
Sbjct: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQ 1086



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 136/528 (25%), Positives = 185/528 (35%), Gaps = 108/528 (20%)

Query: 1844 QQGLPSPTPA-TPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            QQ  P P  +  P  P       P TP PT   QP PP   PP         P++Q    
Sbjct: 696  QQHFPDPAMSFAPVLPP------PSTPMPTGPGQPAPPGQQPP---------PLAQPTPL 740

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH--QMPPMT 1960
             QV  P P    QP  P  PP     A Q+   A    Q+  +Q+ Q P+Q   Q+PP  
Sbjct: 741  PQVLAPQPVVPLQPVPPHLPPYLAP-ASQVGAPA----QLKPLQMPQAPLQPLAQVPPQM 795

Query: 1961 PMAPMGMNPPPMT--RGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSV 2018
            P  P+    PP+T   G  G L P +        PP     +P PQ     +  P++   
Sbjct: 796  PPIPV---VPPITPLAGIDG-LPPALPDLPTATVPP-----VPPPQYFSPAVILPSLA-- 844

Query: 2019 AQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQ--QQVLSILHA 2076
                     AP P        P  P    Q      ++    P +PL    + ++    A
Sbjct: 845  ---------APLP--------PASPALPLQA-----VKLPHPPGAPLAMPCRTIVPNAPA 882

Query: 2077 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM 2136
               LLA      AA   +S    +PGQP  P   P + P  +P     H+   M+   P 
Sbjct: 883  TIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPH-HTVQNMRATPPQ 941

Query: 2137 QAGVQRAGLPQQQ--PQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQ 2194
             A   +  LP Q   P Q   PP   + PQ         T P Q   +L  Q M+  Q  
Sbjct: 942  PALPPQPTLPPQPVLPPQPTLPPQPVLPPQP--------TRPPQ--PVLPPQPMLPPQPV 991

Query: 2195 QGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAG 2254
                P +                   P + + +Q H+ +          Q+   LG  A 
Sbjct: 992  LPPQPAL-------------------PVRPEPLQPHLPEQAAPAATPGSQI--LLGHPA- 1029

Query: 2255 ASLQAYQQRLLQQQMGSPVQP----NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSP 2310
                 Y   +  Q    PV P    +P  P+  +LP    +P L   Q P+SL+    S 
Sbjct: 1030 ----PYAVDVAAQVPTVPVPPAAVLSPPLPEV-LLP---AAPELL-PQFPSSLATVSASV 1080

Query: 2311 QPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANP 2358
            Q VP+      PP + P P      SP      T  P     A+Q  P
Sbjct: 1081 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 80/283 (28%), Positives = 109/283 (38%), Gaps = 49/283 (17%)

Query: 701 QMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQ--- 757
           ++ P + P+      G    A+ P VP Q   + +H Q  QPG   PP    P   Q   
Sbjct: 545 RIWPALQPKEQ-QDVGSPDKARGPPVPLQVQ-VTYHAQAGQPG---PPEPEEPEADQHLL 599

Query: 758 ----PSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQ 813
               P++       + F S G   T    + SS Q+ +  +   ++  P      PP S+
Sbjct: 600 PPTLPTSATSLASDSTFDS-GQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSE 658

Query: 814 GSHIHCPQLPQP-----ALHQNSPSP-VPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPP 867
           G     P LPQ      A  Q + +P +P  +      PPS+    P      APV  PP
Sbjct: 659 G-----PVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPP 713

Query: 868 A--MPPGPQSQA---LHPPPRQTPTP-PTTQLPQQVQPSLP---------------AAPS 906
           +  MP GP   A     PPP   PTP P    PQ V P  P                AP+
Sbjct: 714 STPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPA 773

Query: 907 ADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEG 949
             +P Q P++     A VP    P +PP P  P   P   I+G
Sbjct: 774 QLKPLQMPQAPLQPLAQVP----PQMPPIPVVPPITPLAGIDG 812



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 103/404 (25%), Positives = 146/404 (36%), Gaps = 115/404 (28%)

Query: 671  PGPNMGQPQPGMTSNGPLPD---PSMIRGS---VPNQMMPRITPQSGLNQFGQMSMAQPP 724
            P P +  PQP +    P+P    P +   S    P Q+ P   PQ+ L    Q+    PP
Sbjct: 739  PLPQVLAPQPVVPLQ-PVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797

Query: 725  I--VPRQTP--------PLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQG 774
            I  VP  TP        P       A    + PP  + P +  PS      P +  P+  
Sbjct: 798  IPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALP 855

Query: 775  MNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM---PPGSQGSHIHCP--QLP-QP--- 825
            +    +P  P +  A   +  + ++  P   P++   PPG     IH    QLP QP   
Sbjct: 856  LQAVKLPHPPGAPLAMPCRTIVPNA--PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYP 913

Query: 826  -ALHQNSPSPVPSRTPTPHHTPPSIGAQQP-----------------PATTIPA-----P 862
             A  Q +P+ VP   P+PHHT  ++ A  P                 P  T+P      P
Sbjct: 914  AAFPQMAPTDVP---PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPP 970

Query: 863  VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLP--AAPSADQ----------- 909
             PT P  P  P    L P P   P P     P+ +QP LP  AAP+A             
Sbjct: 971  QPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP 1030

Query: 910  --------------------------------PQQQPRSQQSTAA------SVPTPTAPL 931
                                            P+  P+   S A       SVPT TA L
Sbjct: 1031 YAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATL 1090

Query: 932  LPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
            LPP      + P +     +++P  T   ++  + + E+Q SQ+
Sbjct: 1091 LPP------ANPPLPGGPGIASPCPT--VQLTVEPVQEEQASQD 1126



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 79/331 (23%), Positives = 127/331 (38%), Gaps = 69/331 (20%)

Query: 1846 GLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP--------PYLPRTQAAGPVS 1897
            GL   TPA P   + +  + P+ P P   P+P+P +  P        P LP   A G VS
Sbjct: 1452 GLAPCTPA-PEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP--AAVGAVS 1508

Query: 1898 QGKA------AGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951
               +       G   PP PP   +    GPPP    +   I+   E  R + +       
Sbjct: 1509 LATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLY------- 1561

Query: 1952 IQHQMPPMTPMA--PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSG 2009
             Q  +P  +  A  P+ +     T      LEP              +G  P+ +     
Sbjct: 1562 -QEHVPTSSASAGTPVEVGDRDFT------LEP-------------LRGDQPRSEVCGGD 1601

Query: 2010 MPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPL---- 2065
            +  P +   A  G+     PQP + +  ++P + G V +Q   + +    SP S L    
Sbjct: 1602 LALPPVPKEAVSGRV--QLPQPLVEKSELAPTR-GAVMEQGTSSSMTAESSPRSMLGYDR 1658

Query: 2066 QQQQVLSILH---ANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQ 2122
              +QV S  H   + PQ + AF++    +  + +     G+ G    +P   PP+  G  
Sbjct: 1659 DGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRD----GGEAGESSAEP---PPSDMGTV 1711

Query: 2123 GVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQ 2153
            G       Q  +P   G +  G P+++P+QQ
Sbjct: 1712 G------GQASHPQTLGARALGSPRKRPEQQ 1736



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 130/561 (23%), Positives = 175/561 (31%), Gaps = 134/561 (23%)

Query: 1843 QQQGLPSPTPAT-PTTPTGQQPTTPQTPQPTSQPQPTPPNS----MPPYLPR--TQAAGP 1895
            +QQ + SP  A  P  P   Q T          P+P  P +    +PP LP   T  A  
Sbjct: 554  EQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASD 613

Query: 1896 VSQGKAAGQVTPPTPPQTAQPPLPG------PPPAAVEMAMQIQRAAETQRQMAHVQIFQ 1949
             +     G         + Q  + G      P PA    +  +       + +  +  +Q
Sbjct: 614  STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQ 673

Query: 1950 RPI--------------------QHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGM 1989
            +P                     QH   P    AP+   PPP T  P+G  +P   P G 
Sbjct: 674  QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPV--LPPPSTPMPTGPGQPA--PPG- 728

Query: 1990 QQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKP---GTV 2046
            QQ PP     L QP  L                 P  +APQP +    + P  P      
Sbjct: 729  QQPPP-----LAQPTPL-----------------PQVLAPQPVVPLQPVPPHLPPYLAPA 766

Query: 2047 SQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGM 2106
            SQ      L+ L+ P +PLQ      +    PQ+    +             P+ G  G+
Sbjct: 767  SQVGAPAQLKPLQMPQAPLQP-----LAQVPPQMPPIPVVPPIT--------PLAGIDGL 813

Query: 2107 PQGQPGLQ----PPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMS 2162
            P   P L     PP  P Q   + +PA+  + P  A    A LP   P   LQ       
Sbjct: 814  PPALPDLPTATVPPVPPPQ---YFSPAV--ILPSLA----APLPPASPALPLQAVKLPHP 864

Query: 2163 PQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQ 2222
            P A         +P+    I              A PG+     +    Q P    YP  
Sbjct: 865  PGAPLAMPCRTIVPNAPATI---------PLLAVAPPGVAALSIHSAVAQLPGQPVYP-- 913

Query: 2223 QQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQ 2282
                                   PQ    +   S     Q +        + P P  P Q
Sbjct: 914  --------------------AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQ 953

Query: 2283 HMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP-PHSSPSPRMQPQPSPHHVS 2341
             +LP Q   P              V  PQP   P+P   P P   P P + PQP+   V 
Sbjct: 954  PVLPPQPTLP-----------PQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPA-LPVR 1001

Query: 2342 PQTSSPH-PGLVAAQANPMEQ 2361
            P+   PH P   A  A P  Q
Sbjct: 1002 PEPLQPHLPEQAAPAATPGSQ 1022



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 107/524 (20%), Positives = 176/524 (33%), Gaps = 98/524 (18%)

Query: 1870 QPTSQPQPTPPNSMPPYLP-----------RTQAAGPVSQ------GKAAGQVTP----- 1907
            + T   + + P + PP+L            ++QA  PV Q      GK    + P     
Sbjct: 1263 EDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHP 1322

Query: 1908 -PTPPQTAQP-PLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH--QMPPMTPMA 1963
             P  P+++ P PL   PP A + +   +    ++ Q + +   Q   Q     PP  P A
Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382

Query: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLP-QPQQLQSGMPRPAMMSVAQHG 2022
            P+  + PP+T  P     P             SQ G P  PQ L S +     ++   H 
Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLA-ETHE 1441

Query: 2023 QPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLA 2082
             PL + P      VG++P  P   +        R   +P  PL                 
Sbjct: 1442 APLAVQPL----VVGLAPCTPAPEAAST-----RDASAPREPLPPPA------------- 1479

Query: 2083 AFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQR 2142
                          P+P P   G PQ   G   P +P   G  S    Q  +P       
Sbjct: 1480 --------------PEPSP-HSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP-----PL 1519

Query: 2143 AGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIG 2202
                  QP   L+    G  P+   ++    ++  + R +L ++ +       G    +G
Sbjct: 1520 GPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVG 1579

Query: 2203 PGMANHNQFQ--QPQG------VGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGA--E 2252
                     +  QP+       +  PP  ++ +   +Q  Q   + +  +L    GA  E
Sbjct: 1580 DRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQP--LVEKSELAPTRGAVME 1637

Query: 2253 AGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP 2312
             G S     +   +  +G       ++   H++P+           +P  +   VR  + 
Sbjct: 1638 QGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPS-----------VPQDVPAFVRPARV 1686

Query: 2313 VPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQA 2356
             P+ R   +   SS  P   P      V  Q S  HP  + A+A
Sbjct: 1687 EPTDRDGGEAGESSAEP---PPSDMGTVGGQAS--HPQTLGARA 1725



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 67/219 (30%), Positives = 77/219 (35%), Gaps = 52/219 (23%)

Query: 1834 SMQRTGVVGQQQGLPSPTPATPTTPT-GQQPTTPQ----TPQPTSQPQPT-PPNSM---- 1883
            ++Q       Q  LP P P  P  P    QPT P      PQPT  PQP  PP  M    
Sbjct: 931  TVQNMRATPPQPALP-PQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQ 989

Query: 1884 ----------------PPYLPR--TQAAGPVSQ-----------GKAAGQVTPPTPPQTA 1914
                             P+LP     AA P SQ             AA   T P PP   
Sbjct: 990  PVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAV 1049

Query: 1915 -QPPLPGP-PPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPM 1972
              PPLP    PAA E+  Q   +  T    A VQ         +PP  P  P G  P   
Sbjct: 1050 LSPPLPEVLLPAAPELLPQFPSSLAT--VSASVQSVPTQTATLLPPANPPLPGG--PGIA 1105

Query: 1973 TRGPSGHL--EPGMGPTGMQQQPPWSQGGLPQPQQLQSG 2009
            +  P+  L  EP       Q +PP    GLPQ  +   G
Sbjct: 1106 SPCPTVQLTVEPVQEEQASQDKPP----GLPQSCESYGG 1140



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 55/241 (22%), Positives = 91/241 (37%), Gaps = 27/241 (11%)

Query: 778  TNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCP--QLPQPALHQNSPS-- 833
            T+ P   + G     +++ S ++ PV    +    +   I CP  + P P   ++SP   
Sbjct: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334

Query: 834  -----PVPSRTPTPH-------HTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPP 881
                 P  S+   P+         P  + +QQ  +   P+  P  P  P  P S  +   
Sbjct: 1335 LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTAL 1394

Query: 882  PRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
            P+    P T+ +P+      PA+ +A Q    P + Q   + + T + PL     A    
Sbjct: 1395 PQDGAAPATSTMPE------PASGTASQ-AGGPGTPQGLTSELET-SQPLAETHEAPLAV 1446

Query: 942  QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESK 1001
            QP V      +  P  +ST     A A ++P      E       P+PA  QP  +  + 
Sbjct: 1447 QPLVVGLAPCTPAPEAASTR---DASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA 1503

Query: 1002 V 1002
            V
Sbjct: 1504 V 1504



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 124/546 (22%), Positives = 182/546 (33%), Gaps = 86/546 (15%)

Query: 1850 PTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQ---AAGPVS-QGKAAGQV 1905
            P P +   P   Q + P   Q +S+ QP+       +L   Q    AGP +  G     +
Sbjct: 1332 PLPLSSLPPEASQDSAPYKDQLSSKEQPS-------FLASQQLLSQAGPSNPPGAPPAPL 1384

Query: 1906 TPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMP-PMTPMAP 1964
             P +PP TA P   G  PA   M       A         Q     ++   P   T  AP
Sbjct: 1385 APSSPPVTALPQ-DGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443

Query: 1965 MGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQL---QSGMPRPAMMSVAQH 2021
            + + P          L  G+ P              P P+      +  PR  +   A  
Sbjct: 1444 LAVQP----------LVVGLAPC------------TPAPEAASTRDASAPREPLPPPAPE 1481

Query: 2022 GQPLNMAPQPGLGQVGISPLKPGTVSQQAL--QNLLRTLRSPSSPLQQQQVLSILHANPQ 2079
              P +  PQP LGQ   +PL P  V   +L    L      P+ P Q    L      P 
Sbjct: 1482 PSPHSGTPQPALGQP--APLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539

Query: 2080 LLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMN----- 2134
                F+     K  +   + +  Q  +P        P   G +     P   +       
Sbjct: 1540 PRVGFV-DSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVC 1598

Query: 2135 ---------PMQAGVQRAGLPQQQPQQ-QLQPPMGGMSPQAQQMNMNHNTMPSQFRDILR 2184
                     P +A   R  LPQ   ++ +L P  G +  Q    +M   + P   R +L 
Sbjct: 1599 GGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSP---RSMLG 1655

Query: 2185 RQQMMQQQQQQGAGPGIGPGMANH-NQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIG 2243
                 +  +Q  +   + P +      F +P  V    +          +    +MG +G
Sbjct: 1656 YD---RDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVG 1712

Query: 2244 ---QLPQALGAEAGASLQAYQQRLLQQQMGSPVQP----NPMSPQQ-------HMLPNQA 2289
                 PQ LGA A   L + ++R  QQ + SP +     + +S Q        H L   A
Sbjct: 1713 GQASHPQTLGARA---LGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSA 1769

Query: 2290 QSPHLQGQQIPNS--LSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSP 2347
              P +   + P+S  +   VR  Q   S       P SS S    P+  P  V  Q S P
Sbjct: 1770 -PPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARP-PVQKQASLP 1827

Query: 2348 HPGLVA 2353
              G VA
Sbjct: 1828 VSGSVA 1833



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 68/289 (23%), Positives = 97/289 (33%), Gaps = 46/289 (15%)

Query: 645  EEKRRTR----LQKQNMLPNAAG---MVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGS 697
            EE R+++    + +QN+L        + PV+ +P P   +  P +  +   P+ S     
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348

Query: 698  VPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQ 757
              +Q+                S  QP  +  Q         L+Q G  NPP G  P    
Sbjct: 1349 YKDQLS---------------SKEQPSFLASQQ-------LLSQAGPSNPP-GAPPAPLA 1385

Query: 758  PSNQGQFLPQTQFPSQGMN-VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSH 816
            PS+     P T  P  G    T+    P+SG A  SQA    +   + S +         
Sbjct: 1386 PSSP----PVTALPQDGAAPATSTMPEPASGTA--SQAGGPGTPQGLTSELETSQPLAET 1439

Query: 817  IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQ 876
               P   QP +   +P      TP P     S      P   +P P P P      PQ  
Sbjct: 1440 HEAPLAVQPLVVGLAPC-----TPAPEAA--STRDASAPREPLPPPAPEPSPHSGTPQPA 1492

Query: 877  ALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
               P P          L     PS P  P+   P Q P + +S     P
Sbjct: 1493 LGQPAPLLPAAVGAVSLATSQLPSPPLGPTV--PPQPPSALESDGEGPP 1539



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 59/284 (20%), Positives = 97/284 (34%), Gaps = 26/284 (9%)

Query: 659  PNAAGMVPVSMNPGPNMGQPQPGMT-SNGPLPDPSMIRGS------VPNQMMPRITPQSG 711
            P  A   P++ +  P    PQ G   +   +P+P+    S       P  +   +     
Sbjct: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQP 1435

Query: 712  LNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFP 771
            L +  +  +A  P+V    P          P A +      PR   P    +  P +  P
Sbjct: 1436 LAETHEAPLAVQPLVVGLAPCTP------APEAASTRDASAPREPLPPPAPEPSPHSGTP 1489

Query: 772  SQGMNVTNIPLAPSS-GQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
               +     PL P++ G   ++ +Q+ S       P  PP +  S    P  P+     +
Sbjct: 1490 QPALGQP-APLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP-PRVGFVDS 1547

Query: 831  SPSPVPSRTPT---PHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQ------ALHPP 881
            +   +  +  T     H P S  +   P           P     P+S+      AL P 
Sbjct: 1548 TIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPV 1607

Query: 882  PRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
            P++  +    QLPQ +      AP+     +Q  S   TA S P
Sbjct: 1608 PKEAVSG-RVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSP 1650



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 111/489 (22%), Positives = 176/489 (35%), Gaps = 75/489 (15%)

Query: 643  ELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQM 702
            E    R     ++ + P A    P S  P P +GQP P + +   +   S+    +P+  
Sbjct: 1461 EAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA--AVGAVSLATSQLPSPP 1518

Query: 703  M-PRITPQ--SGLNQFGQMSMAQPPIV------------PRQTPPLQHHGQLAQPGALNP 747
            + P + PQ  S L   G+     PP V              +T   Q H   +   A   
Sbjct: 1519 LGPTVPPQPPSALESDGE---GPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASA-GT 1574

Query: 748  PMGYGPR--MQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSS-CPVN 804
            P+  G R    +P    Q  P+++     + +  +P    SG+  + Q  +  S   P  
Sbjct: 1575 PVEVGDRDFTLEPLRGDQ--PRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTR 1632

Query: 805  SPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPV- 863
              +M  G+  S +     P+  L  +       +  +  H  PS+  Q  PA   PA V 
Sbjct: 1633 GAVMEQGTSSS-MTAESSPRSMLGYDRDG---RQVASDSHVVPSV-PQDVPAFVRPARVE 1687

Query: 864  PT--------------PPAMPPGPQSQALHP---------PPRQTPTPPTTQLPQQVQPS 900
            PT              PP+       QA HP          PR+ P       P +    
Sbjct: 1688 PTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGR 1747

Query: 901  LPAAPSADQ-PQQQPRS-QQSTAASVPTPTAPLLPP-QPATPLSQPAVSIEGQVSNPPST 957
                 + D+     P S + S    V    AP  P  + A   +Q A SIE  V  P S+
Sbjct: 1748 FSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSS 1807

Query: 958  SSTEVNSQA--IAEKQPSQEVK--------MEAKMEVDQPEPADT-QPEDISESKVEDCK 1006
             S +   +A    +KQ S  V          +A   + +P  A +  PE  S   ++   
Sbjct: 1808 DSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPT 1867

Query: 1007 MESTETEERSTELKTEIKEE-EDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEAL 1065
            +  T    +S+ + ++   E ED       QS       +K + +  EL+      +EAL
Sbjct: 1868 ISVTSFHSQSSYISSDNDSELEDADIKKELQS-----LREKHLKEISELQSQQKQEIEAL 1922

Query: 1066 YRQDPESLP 1074
            YR+  + LP
Sbjct: 1923 YRRLGKPLP 1931



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 43/195 (22%), Positives = 72/195 (36%), Gaps = 20/195 (10%)

Query: 850  GAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAA----P 905
            G +  P T +       PA    P+++A  P P++       +  Q+  P L AA    P
Sbjct: 6    GRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGP 65

Query: 906  SADQPQQQ--------PRSQQSTAASVPTPTAP-LLPPQPATPLSQPAVSIE--GQVSNP 954
               QP Q+         R     A   P   AP  L  QP  P +      E  G     
Sbjct: 66   QPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPG 125

Query: 955  PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVD-----QPEPADTQPEDISESKVEDCKMES 1009
            P   +  V +    +  P +E     + E +     +PEP  T+ ++  E + ++  +++
Sbjct: 126  PDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKA 185

Query: 1010 TETEERSTELKTEIK 1024
              T      LK +I+
Sbjct: 186  VATSLDGRFLKFDIE 200



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 27/119 (22%), Positives = 39/119 (32%), Gaps = 7/119 (5%)

Query: 809 PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPA 868
           PPG + +    PQ PQP L +       +R            A+  PA   PA +   P 
Sbjct: 54  PPGLEAAEAPGPQPPQP-LQRRVLLLCKTRRLIAER------ARGRPAAPAPAALVAQPG 106

Query: 869 MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTP 927
            P  P      P   Q P P       +  P+    P  +      +  +  A + P P
Sbjct: 107 APGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEP 165


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 117/433 (27%), Positives = 153/433 (35%), Gaps = 100/433 (23%)

Query: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVA 2019
            +P AP    PPP ++  S     G    G Q        GL +    Q     PA  +  
Sbjct: 384  SPSAP----PPPPSQPQSQAAAAGAAAGGQQAAAGM---GLGKDMGAQYAAASPAWAAAQ 436

Query: 2020 QHGQPLNM--APQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
            Q   P      P P +G+   SP+ P  + +  L  +       S+P          H+ 
Sbjct: 437  QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM------GSNP----------HSQ 480

Query: 2078 PQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM- 2136
            PQ        +++ Y   +  P PG    P G  G  P  M G Q        Q M P  
Sbjct: 481  PQ--------QSSPYPGGSYGP-PGPQRYPIGIQGRTPGAMAGMQY-----PQQQMPPQY 526

Query: 2137 -QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQ 2195
             Q GV       QQP    QP    + PQAQ +       PSQ +   +R Q  Q   Q+
Sbjct: 527  GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL-------PSQSQ---QRYQPQQDMSQE 576

Query: 2196 GAG----PGIGPGMANH---NQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQA 2248
            G G    P + PG  NH   N  QQ +    P                   G I  LP  
Sbjct: 577  GYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS----------------GSIDDLPTG 620

Query: 2249 LGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVR 2308
              A   +++ A      Q    +P Q +P SP          SPHL    IP        
Sbjct: 621  TEATLSSAVSASGSTSSQGDQSNPAQ-SPFSPHA--------SPHLSS--IPGG-----P 664

Query: 2309 SPQPVPSPRPQSQP------PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQG 2362
            SP PV SP   +Q       P S P  +M PQP     S   SS HP L +    P E+G
Sbjct: 665  SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG---SQSESSSHPAL-SQSPMPQERG 720

Query: 2363 HFASPDQNSMLSQ 2375
              A   +N  ++Q
Sbjct: 721  FMAGTQRNPQMAQ 733



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 128/562 (22%), Positives = 196/562 (34%), Gaps = 94/562 (16%)

Query: 1843 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            QQ+  P+ +P TP    G+   +P  P    +PQ     S P   P              
Sbjct: 436  QQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQP-------------- 481

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPM 1962
             Q + P P  +  PP P   P  ++          T   MA +Q      Q QMPP    
Sbjct: 482  -QQSSPYPGGSYGPPGPQRYPIGIQ--------GRTPGAMAGMQY----PQQQMPPQYGQ 528

Query: 1963 APMGMNPPPMTRGPSGHLEPGMGPTGMQQ-QPPWSQGGLPQPQQLQSGMPRPAMMSVAQH 2021
                       +G SG+ + G  P   QQ QPP      PQ Q L S           Q 
Sbjct: 529  -----------QGVSGYCQQGQQPYYSQQPQPPHLP---PQAQYLPS--------QSQQR 566

Query: 2022 GQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLL 2081
             QP     Q G G     PL PG  + + L NL++  R  S P     +  +       L
Sbjct: 567  YQPQQDMSQEGYGTRSQPPLAPGKPNHEDL-NLIQQERPSSLPDLSGSIDDLPTGTEATL 625

Query: 2082 AAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQ 2141
            ++ +    +  +  +       P  P   P L   ++PG  G   +P     +P+ +   
Sbjct: 626  SSAVSASGSTSSQGDQSNPAQSPFSPHASPHLS--SIPG--GPSPSPV---GSPVGSNQS 678

Query: 2142 RAG--LPQQQPQQQLQP-PMGGMSPQAQQMNMNHNTMPSQ--FRDILRRQQMMQQQQQQG 2196
            R+G   P   P  Q+ P P G  S  +    ++ + MP +  F    +R   M Q   Q 
Sbjct: 679  RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738

Query: 2197 AGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEA--- 2253
             GP + P  +   Q     G+    Q      +  Q  Q G  G   + P   G  +   
Sbjct: 739  TGPSMSPHPSPGGQMH--AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASY 796

Query: 2254 -----GASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVR 2308
                 G  + A  Q   Q     P QP    P   M      S  +Q +  P ++S+   
Sbjct: 797  SGPGPGMGISANNQMHGQ----GPSQPCGAVPLGRM-----PSAGMQNRPFPGNMSSMTP 847

Query: 2309 SPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPD 2368
            S    P    Q  P    P P +  +        Q ++      AA +    QG F   +
Sbjct: 848  SS---PGMSQQGGPGMGPPMPTVNRK-------AQEAAAAVMQAAANSAQSRQGSFPGMN 897

Query: 2369 QNSMLSQLASNPGMANLHGASA 2390
            Q+ +++  +S+P    ++ +S+
Sbjct: 898  QSGLMA--SSSPYSQPMNNSSS 917



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 110/448 (24%), Positives = 157/448 (35%), Gaps = 73/448 (16%)

Query: 54   GLTNGGDINQLQTSLGMVQDAASKHKQLS---ELLRSGSSPNLNMGVGGPGQVMASQAQQ 110
            G  N  D+N +Q      Q+  S    LS   + L +G+   L+  V   G   +SQ  Q
Sbjct: 589  GKPNHEDLNLIQ------QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST-SSQGDQ 641

Query: 111  SSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMN-------SPVNQPAM 163
            S+P         +SP +     SP++     GP+  P  S    N       SP + P  
Sbjct: 642  SNPA--------QSPFSPHA--SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGS 691

Query: 164  GMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPL 223
             M         PG  +  +    +    M    G   G Q     NP M   G   T P 
Sbjct: 692  QMPP-----QPPGSQSESSSHPALSQSPMPQERGFMAGTQR----NPQMAQYGPQQTGPS 742

Query: 224  QQGSPQMGGQ-------------TGLRGPQPLKMGMMNNPNPYGSP--YTQNPGQQIGAS 268
                P  GGQ             +G  GPQ  + G   N   Y  P  Y+  P       
Sbjct: 743  MSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGN---YSRPPAYSGVPSASYSGP 799

Query: 269  GLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGM----G 324
            G G+ I     +     P +    AVP G MP+ G Q  P       +TP + GM    G
Sbjct: 800  GPGMGISANNQMHGQ-GP-SQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857

Query: 325  SGAHTADPEKRKLIQQQLVLLLH--AHKCQRREQANGEVRQCNL-----PHCRTMKNVLN 377
             G     P   +  Q+    ++   A+  Q R+ +   + Q  L     P+ + M N  +
Sbjct: 858  PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917

Query: 378  HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAG-DKRNQQPILTGAPVG 436
             M       S   A   SS   +      +  +  + LPLK  G ++   QP        
Sbjct: 918  LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQP----ESKS 973

Query: 437  LGNPSSLGVGQQSAP-NLSTVSQIDPSS 463
              + SS G+ Q   P NL   S + PSS
Sbjct: 974  KDSYSSQGISQPPTPGNLPVPSPMSPSS 1001



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 192/919 (20%), Positives = 289/919 (31%), Gaps = 185/919 (20%)

Query: 88   GSSPNLNMGVGG-PGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQG 146
            GS+   + G GG  G        Q SPG+G+++S   +     G   P        PN  
Sbjct: 177  GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236

Query: 147  PTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQ 206
                 G      ++P  G   G   G   G    G G G        G++ A        
Sbjct: 237  CNHYPG-----YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 207  YPNPGMGSAG------NLLTEPLQQGSPQM-----GGQTGL------------------- 236
                G G  G       +L+ P QQG   M     GG   L                   
Sbjct: 292  AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351

Query: 237  ---RGPQPLKMGMMNNPNP-----------YGSPYTQNP-----------------GQQI 265
                G  P    ++ +P+P           Y SP    P                 GQQ 
Sbjct: 352  QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411

Query: 266  GAS-GLGLQIQTKTVLSNNLSPFAMDKK---AVPGGGMPNMGQQPAPQVQQPGLVTPVAQ 321
             A  GLG  +  +   ++     A  +      PG   P MG+     +    +  P   
Sbjct: 412  AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLY 471

Query: 322  GMGSGAHTADPEKRKLI--------QQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMK 373
            GMGS  H+   +              Q+  + +          A  +  Q  +P     +
Sbjct: 472  GMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR--TPGAMAGMQYPQQQMPPQYGQQ 529

Query: 374  NVLNHMTHCQSG------KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQ 427
             V     +CQ G      +  Q  H     Q +   ++  R+     +  +  G  R+Q 
Sbjct: 530  GVSG---YCQQGQQPYYSQQPQPPHLPPQAQYLPS-QSQQRYQPQQDMSQEGYG-TRSQP 584

Query: 428  PILTGAP-------VGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERA---YAALGLPYQV 477
            P+  G P       +    PSSL     S  +L T ++   SS   A    ++ G     
Sbjct: 585  PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNP 644

Query: 478  NQMPTQPQVQAK-NQQNQQPGQSPQGMRPMSNMS----ASPMGVNGG-VGVQTPSLLSDS 531
             Q P  P      +     P  SP G    SN S     SP  + G  +  Q P   S+S
Sbjct: 645  AQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSES 704

Query: 532  MLHSAINSQNPMMSENASVPSLGPMPTAAQ--PSTTGIRKQWHEDITQDLRNHLVHKLVQ 589
              H A+ SQ+PM  E   +      P  AQ  P  TG                       
Sbjct: 705  SSHPAL-SQSPMPQERGFMAGTQRNPQMAQYGPQQTG----------------------P 741

Query: 590  AIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRR 649
            ++ P P P       + +            ++ +N+   Y   +++  Y  Q        
Sbjct: 742  SMSPHPSPGGQMHAGISS------------FQQSNSSGTYGPQMSQ--YGPQGNY----- 782

Query: 650  TRLQKQNMLPNAA------GMVPVSMNPGPNMGQPQP-GMTSNGPLPDPSMIRGSVPNQM 702
            +R    + +P+A+      GM   + N     G  QP G    G +P   M     P  M
Sbjct: 783  SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 703  MPRITPQSGLNQFGQMSMAQP-PIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQ 761
                    G++Q G   M  P P V R+          A   +     G  P M Q    
Sbjct: 843  SSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLM 902

Query: 762  GQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVN-SPIMPPGSQGSHIHCP 820
                P +Q  +   ++ N    P S    ++ A ++SS+  V  + +M PG         
Sbjct: 903  ASSSPYSQPMNNSSSLMNTQAPPYS----MAPAMVNSSAASVGLADMMSPGES------- 951

Query: 821  QLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPP--------- 871
            +LP P          P        +  S G  QPP    P  +P P  M P         
Sbjct: 952  KLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT---PGNLPVPSPMSPSSASISSFH 1008

Query: 872  GPQSQALHPPP-RQTPTPP 889
            G +S ++  P   +TP+ P
Sbjct: 1009 GDESDSISSPGWPKTPSSP 1027



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 123/572 (21%), Positives = 193/572 (33%), Gaps = 123/572 (21%)

Query: 1888 PRTQAAGPVSQGKAAGQVTPPTP--------PQTAQPPLPGPPPAAVEMAMQIQRAA--E 1937
            P+ Q   P + G   G  TP +         P   +PP P   P      MQ  R++   
Sbjct: 1158 PKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTIS 1217

Query: 1938 TQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWS- 1996
                 + V     P ++ M P  P       P  M R P    EP   P G  ++ P S 
Sbjct: 1218 VHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMP---YEPNKDPFGGMRKVPGSS 1274

Query: 1997 -----QGGLPQP--QQLQSGMPRPAMMSVAQ------------------HGQPLNMAPQP 2031
                 QG +P    Q + +  P  AM ++                    +GQ       P
Sbjct: 1275 EPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQY-PGQGP 1333

Query: 2032 GLGQVGISPLKPGTVSQQA-LQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAA 2090
              GQ      +PG   QQ   +  +  +  P +   +  + ++ +++ Q       Q   
Sbjct: 1334 PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ--QEMYNQYGG 1391

Query: 2091 KYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP 2150
             Y+  + +PI GQ   P  +  +Q    PGQ                  +Q  G+    P
Sbjct: 1392 SYSGPDRRPIQGQYPYPYSRERMQG---PGQ------------------IQTHGI----P 1426

Query: 2151 QQQLQPPMGGMSPQAQQMNM--NHNTMPSQFRDILRRQQMMQQQQQQGAGPGIG---PGM 2205
             Q +  P+   S +  Q NM    N MP  +           Q +Q   GP      PGM
Sbjct: 1427 PQMMGGPLQSSSSEGPQQNMWAARNDMPYPY-----------QNRQGPGGPTQAPPYPGM 1475

Query: 2206 ANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLL 2265
               +    P          QR+ H  Q         + Q    + + A            
Sbjct: 1476 NRTDDMMVP---------DQRINHESQW-----PSHVSQRQPYMSSSAS----------- 1510

Query: 2266 QQQMGSPVQPNPMSPQQHMLPN---QAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP 2322
             Q +  P QP+  +P    LPN   +A SP    + + N +S   +SP  +PS + Q   
Sbjct: 1511 MQPITRPPQPSYQTPPS--LPNHISRAPSPASFQRSLENRMSPS-KSPF-LPSMKMQKVM 1566

Query: 2323 PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGH------FASPDQNSMLSQL 2376
            P    S    P P P  +  + + P PG V A    ++Q          +P+   ++  L
Sbjct: 1567 PTVPTSQVTGPPPQPPPIRREITFP-PGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSL 1625

Query: 2377 ASNPGMANLHGASATDLGLSTDNSDLNSNLSQ 2408
             S     +       ++ L  D++    NLSQ
Sbjct: 1626 KSGLLAESTWALDTINILLYDDSTVATFNLSQ 1657



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 118/587 (20%), Positives = 186/587 (31%), Gaps = 128/587 (21%)

Query: 471  LGLPYQVNQMPTQPQVQAKNQQNQQPGQSP----QGMRPMSNM----SASPMGVNGGVGV 522
            + +P  + +MP +P         + PG S     QG  P S+M    + SP G    +G+
Sbjct: 1246 MSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGM 1305

Query: 523  ----QTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQWHEDITQD 578
                Q P   S    H     Q P     +  P  G       P     ++         
Sbjct: 1306 GQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH-------- 1357

Query: 579  LRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIY 638
                     +  ++  P                A++ EGDMY       +Y     E   
Sbjct: 1358 ---------MDGMYGPP----------------AKRHEGDMYNM-----QYSSQQQEMYN 1387

Query: 639  KIQKELEEKRRTRLQKQNMLP------NAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPS 692
            +         R  +Q Q   P         G +     P   MG P    +S GP  +  
Sbjct: 1388 QYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMW 1447

Query: 693  MIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYG 752
              R  +P     R                Q P  P Q PP  + G       + P     
Sbjct: 1448 AARNDMPYPYQNR----------------QGPGGPTQAPP--YPGMNRTDDMMVPDQRIN 1489

Query: 753  PRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGS 812
               Q PS+  Q  P               ++ S+   P+++    S   P + P      
Sbjct: 1490 HESQWPSHVSQRQPY--------------MSSSASMQPITRPPQPSYQTPPSLPN----- 1530

Query: 813  QGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPG 872
                 H  + P PA  Q S     S + +P    PS+  Q+   T   + V  PP  PP 
Sbjct: 1531 -----HISRAPSPASFQRSLENRMSPSKSPFL--PSMKMQKVMPTVPTSQVTGPPPQPPP 1583

Query: 873  PQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLL 932
             + +   PP     + P  +  +++       P A +     +S     ++    T  +L
Sbjct: 1584 IRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINIL 1643

Query: 933  PPQPAT----PLSQPAVSIEGQVS------------------NPPSTSSTEVNSQAIAEK 970
                +T     LSQ +  +E  V                     PS  + + N+   A K
Sbjct: 1644 LYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNA---ARK 1700

Query: 971  QPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERST 1017
              SQ +  ++  E +  E  D   ED  E + ED   E TE++E+S+
Sbjct: 1701 DDSQSLADDSGKEEEDAECIDDDEED-EEDEEED--SEKTESDEKSS 1744



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 80/396 (20%), Positives = 139/396 (35%), Gaps = 38/396 (9%)

Query: 662  AGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQ--MMPRITPQSGLNQFGQMS 719
            +G +  +  PG  M  PQP  + +     P++ +  +P +   M        + Q+G   
Sbjct: 680  SGPISPASIPGSQM-PPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738

Query: 720  MAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTN 779
               P + P  +P  Q H  ++     N    YGP+M Q   QG +       S+    + 
Sbjct: 739  TG-PSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNY-------SRPPAYSG 790

Query: 780  IPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRT 839
            +P A  SG  P      +++      P  P G+    +   ++P   + QN P P    +
Sbjct: 791  VPSASYSGPGP-GMGISANNQMHGQGPSQPCGA----VPLGRMPSAGM-QNRPFPGNMSS 844

Query: 840  PTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP 899
             TP  + P +  Q  P    P P     A      + A+      +        P   Q 
Sbjct: 845  MTP--SSPGMSQQGGPGMGPPMPTVNRKAQ---EAAAAVMQAAANSAQSRQGSFPGMNQS 899

Query: 900  SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959
             L A+ S   P  QP +  S+  +   P   + P    +  S  +V +   +S   S   
Sbjct: 900  GLMASSS---PYSQPMNNSSSLMNTQAPPYSMAPAMVNS--SAASVGLADMMSPGESKLP 954

Query: 960  TEVNSQAIAEKQPSQEVKME---AKMEVDQPEPADT--QPEDISESKVEDCKMESTETEE 1014
              + +    E  P  E K +   +   + QP        P  +S S          E++ 
Sbjct: 955  LPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDS 1014

Query: 1015 RSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFK 1050
             S+            PS+  + SS   G+   K+++
Sbjct: 1015 ISS------PGWPKTPSSPKSSSSTTTGEKITKVYE 1044



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 79/357 (22%), Positives = 121/357 (33%), Gaps = 71/357 (19%)

Query: 653  QKQNMLPNAAGMVPVSMNPGPNMGQPQ-PGMTSNGPLPDPSMIRGSVPNQMMPRITPQSG 711
            Q+   +P+  G +P   N  P  G  + PG +      +P M +G +PN  M  +  QS 
Sbjct: 1243 QQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSS------EPFMTQGQMPNSSMQDMYNQSP 1296

Query: 712  LNQFGQMSMAQPPIVP-------RQTPPLQHHGQLAQPGALNPPMGYGPRM--QQPSNQ- 761
                  + M Q    P       R  P  Q +     P    P  G+ P +  QQP+ + 
Sbjct: 1297 SGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKR 1356

Query: 762  ---GQFLPQT----------QFPSQ--------GMNVTNIPLAPSSGQAPVSQA------ 794
               G + P            Q+ SQ        G + +     P  GQ P   +      
Sbjct: 1357 HMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1416

Query: 795  --QMSSSSCP---VNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT--PHHTPP 847
              Q+ +   P   +  P+    S+G     PQ    A   + P P  +R     P   PP
Sbjct: 1417 PGQIQTHGIPPQMMGGPLQSSSSEG-----PQQNMWAARNDMPYPYQNRQGPGGPTQAPP 1471

Query: 848  SIGAQQPPATTIPA---------PVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQ 898
              G  +     +P          P       P    S ++ P  R  P  P+ Q P  + 
Sbjct: 1472 YPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITR--PPQPSYQTPPSLP 1529

Query: 899  PSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPP 955
              +  APS    Q+   ++ S + S   P+  +    P  P SQ    + G    PP
Sbjct: 1530 NHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQ----VTGPPPQPP 1582



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 117/562 (20%), Positives = 180/562 (32%), Gaps = 119/562 (21%)

Query: 1842 GQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKA 1901
            G+++G P P   +  + + Q  + P TP     P P  P+S         A+     G  
Sbjct: 961  GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSS---------ASISSFHGDE 1011

Query: 1902 AGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTP 1961
            +  ++ P  P+T   P         E   ++        +   V  +   ++ +  P++ 
Sbjct: 1012 SDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSS 1071

Query: 1962 MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSV-AQ 2020
            +  +G  P  + R      E G G   + +   W +        L  G    A  S+  Q
Sbjct: 1072 LPAVGKKPLDLFRLYVCVKEIG-GLAQVNKNKKWRE----LATNLNVGTSSSAASSLKKQ 1126

Query: 2021 HGQPL---------NMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVL 2071
            + Q L            P P +   G       T  Q  LQ        P SP       
Sbjct: 1127 YIQYLFAFECKIERGEEPPPEVFSTG------DTKKQPKLQ--------PPSP------- 1165

Query: 2072 SILHANPQLLAAFIKQRAAKYANSNPQPIPG--QPGMPQGQPGLQPPTMPGQQ----GVH 2125
                AN   L     Q      +++   +PG  +P  P   P  Q   M G +     VH
Sbjct: 1166 ----ANSGSLQG--PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVH 1219

Query: 2126 ---------SNPAMQNMN---PMQAGVQRAGLPQQQPQQQLQPPMGGMS--PQAQQMNMN 2171
                     S P   +M    P Q G+    +  + P +  + P GGM   P + +  M 
Sbjct: 1220 DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMT 1279

Query: 2172 HNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGM-------ANHNQFQQPQGVGYPPQ-- 2222
               MP+         Q M  Q   GA   +G G        A++++  +P G  YP Q  
Sbjct: 1280 QGQMPNS------SMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGP 1333

Query: 2223 ----------------QQQRMQHHMQQM-------QQGNM--GQIGQLPQALGAEAGASL 2257
                            QQ   + HM  M        +G+M   Q     Q +  + G S 
Sbjct: 1334 PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1393

Query: 2258 QAYQQRLLQQQMGSPV----QPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPV 2313
                +R +Q Q   P        P   Q H +P Q     LQ         N   +   +
Sbjct: 1394 SGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDM 1453

Query: 2314 PSPRPQSQ----PPHSSPSPRM 2331
            P P    Q    P  + P P M
Sbjct: 1454 PYPYQNRQGPGGPTQAPPYPGM 1475



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 79/318 (24%), Positives = 103/318 (32%), Gaps = 71/318 (22%)

Query: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL 2154
            S+P   P  P  PQ Q         GQQ        ++M    A    A  P     QQ 
Sbjct: 383  SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYA----AASPAWAAAQQR 438

Query: 2155 QPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP 2214
              P   MSP      M  +        +++R Q+             G G   H+Q QQ 
Sbjct: 439  SHP--AMSPGTPGPTMGRSQGSPMDPMVMKRPQLY------------GMGSNPHSQPQQS 484

Query: 2215 Q---GVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGS 2271
                G  Y P   QR    +Q          G+ P   GA AG                 
Sbjct: 485  SPYPGGSYGPPGPQRYPIGIQ----------GRTP---GAMAGMQY-------------- 517

Query: 2272 PVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRM 2331
                    PQQ M P         GQQ  +    Q    QP  S +PQ  PPH  P  + 
Sbjct: 518  --------PQQQMPPQY-------GQQGVSGYCQQ--GQQPYYSQQPQ--PPHLPPQAQY 558

Query: 2332 QPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASAT 2391
             P  S     PQ      G       P+  G     D N +  +  S+  + +L G S  
Sbjct: 559  LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS--LPDLSG-SID 615

Query: 2392 DLGLSTDNSDLNSNLSQS 2409
            DL   T+ + L+S +S S
Sbjct: 616  DLPTGTE-ATLSSAVSAS 632



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 44/198 (22%), Positives = 78/198 (39%), Gaps = 40/198 (20%)

Query: 629 YYHLLAEKIYKIQKELEEKRRTRLQKQ---------NMLPNAAGMVPVSMNPGPNMGQPQ 679
           ++H L +++ + Q++ +++++ + Q+Q         N L  A G  P    PGP+M QPQ
Sbjct: 44  HHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAP---QPGPDMEQPQ 100

Query: 680 PGMTSNG-------PLPDPSMIRGSVPNQMMPRITPQSGLNQ----FGQMSMAQPPIV-- 726
            G   +        P   P + +    +   P++   +G        G +   QPP+   
Sbjct: 101 HGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP 160

Query: 727 -----PRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIP 781
                P   P   ++   A P +  P    GP   Q   Q          S GM + +  
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ---------QSPGMGMMHSA 211

Query: 782 LAPSSGQAPVSQAQMSSS 799
            A ++G AP S   + +S
Sbjct: 212 SAAAAG-APGSMDPLQNS 228



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 83/407 (20%), Positives = 122/407 (29%), Gaps = 41/407 (10%)

Query: 670  NPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQ 729
            N  P+   P        P P      GS P    P   P        Q + A      +Q
Sbjct: 351  NQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQ 410

Query: 730  TPPLQHHGQL--AQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSG 787
                   G+   AQ  A +P      +   P+      P T  P+ G +  + P+ P   
Sbjct: 411  AAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMS----PGTPGPTMGRSQGS-PMDPMVM 465

Query: 788  QAPVSQAQMSSS-SCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP 846
            + P      S+  S P  S   P GS G     PQ     +   +P  +          P
Sbjct: 466  KRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAGMQYPQQQMP 523

Query: 847  PSIGAQ------QPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS 900
            P  G Q      Q       +  P PP +PP  Q        R  P    +Q     +  
Sbjct: 524  PQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQ 583

Query: 901  LPAAPSADQPQQQPRSQQSTAASVPTPTAPL--LPPQPATPLSQP-----AVSIEGQVSN 953
             P AP     +     QQ   +S+P  +  +  LP      LS       + S +G  SN
Sbjct: 584  PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643

Query: 954  P----------------PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQ--PEPADTQPE 995
            P                P   S       +   Q        A +   Q  P+P  +Q E
Sbjct: 644  PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703

Query: 996  DISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042
              S   +    M         T+   ++ +   Q +  +    P+PG
Sbjct: 704  SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 82/347 (23%), Positives = 110/347 (31%), Gaps = 83/347 (23%)

Query: 8   PGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTS 67
           P PP ++    S PALS S                +P       E G   G   N     
Sbjct: 695 PQPPGSQSESSSHPALSQS---------------PMPQ------ERGFMAGTQRNPQMAQ 733

Query: 68  LGMVQDAAS----------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGL 117
            G  Q   S           H  +S   +S SS     G  GP      Q  Q  P    
Sbjct: 734 YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSS-----GTYGP------QMSQYGPQGNY 782

Query: 118 INSMVKSPMTQAGLTSPNMGMGTSGPN----QGPTQ-----------STGMMNSPV--NQ 160
                 S +  A  + P  GMG S  N    QGP+Q           S GM N P   N 
Sbjct: 783 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 161 PAM-----GMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSA 215
            +M     GM+     GM P M             VM  +  + + RQ      PGM  +
Sbjct: 843 SSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG---SFPGMNQS 899

Query: 216 GNL-----LTEPLQQGSPQMGGQTGLRGPQPLKMGMMN-NPNPYGSPYTQNPGQQIGASG 269
           G +      ++P+   S  M  Q     P  +   M+N +    G     +PG+    S 
Sbjct: 900 GLMASSSPYSQPMNNSSSLMNTQA---PPYSMAPAMVNSSAASVGLADMMSPGE----SK 952

Query: 270 LGLQIQTKTVLSNNLSPFAMDKKAVPGGGM---PNMGQQPAPQVQQP 313
           L L ++          P +  K +    G+   P  G  P P    P
Sbjct: 953 LPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSP 999



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 51/229 (22%), Positives = 79/229 (34%), Gaps = 42/229 (18%)

Query: 1846 GLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQV 1905
            G+PS + + P    G         Q  SQP    P    P         P +       +
Sbjct: 790  GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS----M 845

Query: 1906 TPPTPPQTAQ------PPLPGPPPAAVEMAMQIQRAAETQRQ--------------MAHV 1945
            TP +P  + Q      PP+P     A E A  + +AA    Q              MA  
Sbjct: 846  TPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS 905

Query: 1946 QIFQRPIQH-------QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQG 1998
              + +P+ +       Q PP + MAP  +N    + G +  + PG     +  +    + 
Sbjct: 906  SPYSQPMNNSSSLMNTQAPPYS-MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 964

Query: 1999 GLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVS 2047
            G PQP+              +   Q ++  P PG   V  SP+ P + S
Sbjct: 965  GTPQPESKSKD---------SYSSQGISQPPTPGNLPVP-SPMSPSSAS 1003



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 45/190 (23%), Positives = 62/190 (32%), Gaps = 29/190 (15%)

Query: 2209 NQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQ 2268
            NQFQQ Q      QQQQ+ Q H         G  G  PQ      G  ++  Q    +  
Sbjct: 53   NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ-----PGPDMEQPQHGGAKDS 107

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSP- 2327
                    P  P      ++  +P   G+          R   P        QPP + P 
Sbjct: 108  AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGG------RYEHPGLGALGTQQPPVAVPG 161

Query: 2328 ---SPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384
                P   P+ + ++ S   +S  PG    +A P    H               +PGM  
Sbjct: 162  GGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGGQ-----------QSPGMGM 207

Query: 2385 LHGASATDLG 2394
            +H ASA   G
Sbjct: 208  MHSASAAAAG 217


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 117/433 (27%), Positives = 153/433 (35%), Gaps = 100/433 (23%)

Query: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVA 2019
            +P AP    PPP ++  S     G    G Q        GL +    Q     PA  +  
Sbjct: 384  SPSAP----PPPPSQPQSQAAAAGAAAGGQQAAAGM---GLGKDMGAQYAAASPAWAAAQ 436

Query: 2020 QHGQPLNM--APQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
            Q   P      P P +G+   SP+ P  + +  L  +       S+P          H+ 
Sbjct: 437  QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM------GSNP----------HSQ 480

Query: 2078 PQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM- 2136
            PQ        +++ Y   +  P PG    P G  G  P  M G Q        Q M P  
Sbjct: 481  PQ--------QSSPYPGGSYGP-PGPQRYPIGIQGRTPGAMAGMQY-----PQQQMPPQY 526

Query: 2137 -QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQ 2195
             Q GV       QQP    QP    + PQAQ +       PSQ +   +R Q  Q   Q+
Sbjct: 527  GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL-------PSQSQ---QRYQPQQDMSQE 576

Query: 2196 GAG----PGIGPGMANH---NQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQA 2248
            G G    P + PG  NH   N  QQ +    P                   G I  LP  
Sbjct: 577  GYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS----------------GSIDDLPTG 620

Query: 2249 LGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVR 2308
              A   +++ A      Q    +P Q +P SP          SPHL    IP        
Sbjct: 621  TEATLSSAVSASGSTSSQGDQSNPAQ-SPFSPHA--------SPHLSS--IPGG-----P 664

Query: 2309 SPQPVPSPRPQSQP------PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQG 2362
            SP PV SP   +Q       P S P  +M PQP     S   SS HP L +    P E+G
Sbjct: 665  SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG---SQSESSSHPAL-SQSPMPQERG 720

Query: 2363 HFASPDQNSMLSQ 2375
              A   +N  ++Q
Sbjct: 721  FMAGTQRNPQMAQ 733



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 128/562 (22%), Positives = 196/562 (34%), Gaps = 94/562 (16%)

Query: 1843 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAA 1902
            QQ+  P+ +P TP    G+   +P  P    +PQ     S P   P              
Sbjct: 436  QQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQP-------------- 481

Query: 1903 GQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPM 1962
             Q + P P  +  PP P   P  ++          T   MA +Q      Q QMPP    
Sbjct: 482  -QQSSPYPGGSYGPPGPQRYPIGIQ--------GRTPGAMAGMQY----PQQQMPPQYGQ 528

Query: 1963 APMGMNPPPMTRGPSGHLEPGMGPTGMQQ-QPPWSQGGLPQPQQLQSGMPRPAMMSVAQH 2021
                       +G SG+ + G  P   QQ QPP      PQ Q L S           Q 
Sbjct: 529  -----------QGVSGYCQQGQQPYYSQQPQPPHLP---PQAQYLPS--------QSQQR 566

Query: 2022 GQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLL 2081
             QP     Q G G     PL PG  + + L NL++  R  S P     +  +       L
Sbjct: 567  YQPQQDMSQEGYGTRSQPPLAPGKPNHEDL-NLIQQERPSSLPDLSGSIDDLPTGTEATL 625

Query: 2082 AAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQ 2141
            ++ +    +  +  +       P  P   P L   ++PG  G   +P     +P+ +   
Sbjct: 626  SSAVSASGSTSSQGDQSNPAQSPFSPHASPHLS--SIPG--GPSPSPV---GSPVGSNQS 678

Query: 2142 RAG--LPQQQPQQQLQP-PMGGMSPQAQQMNMNHNTMPSQ--FRDILRRQQMMQQQQQQG 2196
            R+G   P   P  Q+ P P G  S  +    ++ + MP +  F    +R   M Q   Q 
Sbjct: 679  RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738

Query: 2197 AGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEA--- 2253
             GP + P  +   Q     G+    Q      +  Q  Q G  G   + P   G  +   
Sbjct: 739  TGPSMSPHPSPGGQMH--AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASY 796

Query: 2254 -----GASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVR 2308
                 G  + A  Q   Q     P QP    P   M      S  +Q +  P ++S+   
Sbjct: 797  SGPGPGMGISANNQMHGQ----GPSQPCGAVPLGRM-----PSAGMQNRPFPGNMSSMTP 847

Query: 2309 SPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPD 2368
            S    P    Q  P    P P +  +        Q ++      AA +    QG F   +
Sbjct: 848  SS---PGMSQQGGPGMGPPMPTVNRK-------AQEAAAAVMQAAANSAQSRQGSFPGMN 897

Query: 2369 QNSMLSQLASNPGMANLHGASA 2390
            Q+ +++  +S+P    ++ +S+
Sbjct: 898  QSGLMA--SSSPYSQPMNNSSS 917



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 202/1014 (19%), Positives = 323/1014 (31%), Gaps = 210/1014 (20%)

Query: 88   GSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGP 147
            G S N  M   GP Q   +      P  G+ N      M+    +SP M     GP  GP
Sbjct: 804  GISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ-QGGPGMGP 862

Query: 148  TQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPN-----QVMNGSIGAGRGR 202
               T    +     A+      +A    G     N  G+M +     Q MN S       
Sbjct: 863  PMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSL---- 918

Query: 203  QNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPG 262
             N Q P   M  A  + +     G   M      + P PLK     +    G+P  ++  
Sbjct: 919  MNTQAPPYSMAPA-MVNSSAASVGLADMMSPGESKLPLPLKA----DGKEEGTPQPESKS 973

Query: 263  QQIGASG-----------LGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQ-- 309
            ++  +S            LG + + K  +   L+   M+++  P   +P +G++P     
Sbjct: 974  KKSSSSTTTGEKITKVYELGNEPERKLWVDRYLT--FMEERGSPVSSLPAVGKKPLDLFR 1031

Query: 310  ----VQQPGLVTPVAQG-----------MGSGAHTADPEKRKLIQQQLVLLLHAHKCQRR 354
                V++ G +  V +            +G+ +  A   K++ IQ    L     K +R 
Sbjct: 1032 LYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQY---LFAFECKIERG 1088

Query: 355  EQANGEV-------RQCNL-PHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNC 406
            E+   EV       +Q  L P        L      QS  S  +A      +        
Sbjct: 1089 EEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK-------- 1140

Query: 407  TRHDCPVCLPLKNAGDKRNQQPILTG---APVGLGNPSSLGVGQQSAPNLSTVSQIDPSS 463
                     P   A     Q   + G   + + + +P S  V   S P  ++++   P  
Sbjct: 1141 ---------PPTPASTPHGQMTPMQGGRSSTISVHDPFS-DVSDSSFPKRNSMTPNAPYQ 1190

Query: 464  IERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSP----QGMRPMSNM----SASPMG 515
                   + +P  + +MP +P         + PG S     QG  P S+M    + SP G
Sbjct: 1191 -----QGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSG 1245

Query: 516  VNGGVGV----QTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTGIRKQW 571
                +G+    Q P   S    H     Q P     +  P  G       P     ++  
Sbjct: 1246 AMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH- 1304

Query: 572  HEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYH 631
                            +  ++  P                A++ EGDMY       +Y  
Sbjct: 1305 ----------------MDGMYGPP----------------AKRHEGDMYNM-----QYSS 1327

Query: 632  LLAEKIYKIQKELEEKRRTRLQKQNMLP------NAAGMVPVSMNPGPNMGQPQPGMTSN 685
               E   +         R  +Q Q   P         G +     P   MG P    +S 
Sbjct: 1328 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1387

Query: 686  GPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGAL 745
            GP  +    R  +P     R                Q P  P Q PP  + G       +
Sbjct: 1388 GPQQNMWAARNDMPYPYQNR----------------QGPGGPTQAPP--YPGMNRTDDMM 1429

Query: 746  NPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNS 805
             P        Q PS+  Q  P               ++ S+   P+++    S   P + 
Sbjct: 1430 VPDQRINHESQWPSHVSQRQPY--------------MSSSASMQPITRPPQPSYQTPPSL 1475

Query: 806  PIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPT 865
            P           H  + P PA  Q S     S + +P    PS+  Q+   T   + V  
Sbjct: 1476 PN----------HISRAPSPASFQRSLENRMSPSKSPFL--PSMKMQKVMPTVPTSQVTG 1523

Query: 866  PPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP 925
            PP  PP  + +   PP     + P  +  +++       P A +     +S     ++  
Sbjct: 1524 PPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWA 1583

Query: 926  TPTAPLLPPQPAT----PLSQPAVSIEGQVS------------------NPPSTSSTEVN 963
              T  +L    +T     LSQ +  +E  V                     PS  + + N
Sbjct: 1584 LDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHN 1643

Query: 964  SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERST 1017
            +   A K  SQ +  ++  E +  E  D   ED  E + ED   E TE++E+S+
Sbjct: 1644 A---ARKDDSQSLADDSGKEEEDAECIDDDEED-EEDEEED--SEKTESDEKSS 1691



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 168/750 (22%), Positives = 244/750 (32%), Gaps = 147/750 (19%)

Query: 87  SGSSPNLNMGVGGPGQVMASQA----QQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSG 142
           SG++P LN  +  P  +M S      + SSP           P +QA       G   + 
Sbjct: 355 SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAP--PPPPSQPQSQAAAAGAAAGGQQAA 412

Query: 143 PNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGR 202
              G  +  G   +  +          +  M+PG           P   M  S G+    
Sbjct: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGT----------PGPTMGRSQGSPMDP 462

Query: 203 QNMQYPNP-GMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNP 261
             M+ P   GMGS  N  ++P QQ SP  GG  G  GPQ   +G+     P      Q P
Sbjct: 463 MVMKRPQLYGMGS--NPHSQP-QQSSPYPGGSYGPPGPQRYPIGIQGR-TPGAMAGMQYP 518

Query: 262 GQQI-------GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPG 314
            QQ+       G SG   Q Q +   S    P  +  +A           QP   + Q G
Sbjct: 519 QQQMPPQYGQQGVSGYCQQGQ-QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 577

Query: 315 LVTPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKN 374
             T     +  G    + E   LIQQ+                    R  +LP      +
Sbjct: 578 YGTRSQPPLAPG--KPNHEDLNLIQQE--------------------RPSSLPDLSGSID 615

Query: 375 VLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAP 434
            L   T      +   +   SS+   S+         P   P        +  P L+  P
Sbjct: 616 DLPTGTEATLSSAVSASGSTSSQGDQSN---------PAQSPF-----SPHASPHLSSIP 661

Query: 435 VGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQ 494
              G PS   VG     N S    I P+SI             +QMP QP          
Sbjct: 662 ---GGPSPSPVGSPVGSNQSRSGPISPASIPG-----------SQMPPQP---------- 697

Query: 495 QPG-QSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSE---NASV 550
            PG QS     P   +S SPM    G    T               +NP M++     + 
Sbjct: 698 -PGSQSESSSHPA--LSQSPMPQERGFMAGT--------------QRNPQMAQYGPQQTG 740

Query: 551 PSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPD-----PAALKDRRM 605
           PS+ P P+       GI      + +      +     Q  +  P      P+A      
Sbjct: 741 PSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSA------ 794

Query: 606 ENLVAYARKVEGDMYESANN----RAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNA 661
               +Y+    G M  SANN    +       A  + ++     + R       +M P++
Sbjct: 795 ----SYSGPGPG-MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849

Query: 662 AGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA 721
            GM   S   GP MG P P +         ++++ +  N    R     G+NQ G M+ +
Sbjct: 850 PGM---SQQGGPGMGPPMPTVNRKAQEAAAAVMQAAA-NSAQSRQGSFPGMNQSGLMASS 905

Query: 722 QPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIP 781
            P      + P+ +   L    A  PP    P M   S     L     P  G +   +P
Sbjct: 906 SP-----YSQPMNNSSSLMNTQA--PPYSMAPAMVNSSAASVGLADMMSP--GESKLPLP 956

Query: 782 LAPSSGQ----APVSQAQMSSSSCPVNSPI 807
           L     +     P S+++ SSSS      I
Sbjct: 957 LKADGKEEGTPQPESKSKKSSSSTTTGEKI 986



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 123/572 (21%), Positives = 193/572 (33%), Gaps = 123/572 (21%)

Query: 1888 PRTQAAGPVSQGKAAGQVTPPTP--------PQTAQPPLPGPPPAAVEMAMQIQRAA--E 1937
            P+ Q   P + G   G  TP +         P   +PP P   P      MQ  R++   
Sbjct: 1105 PKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTIS 1164

Query: 1938 TQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWS- 1996
                 + V     P ++ M P  P       P  M R P    EP   P G  ++ P S 
Sbjct: 1165 VHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMP---YEPNKDPFGGMRKVPGSS 1221

Query: 1997 -----QGGLPQP--QQLQSGMPRPAMMSVAQ------------------HGQPLNMAPQP 2031
                 QG +P    Q + +  P  AM ++                    +GQ       P
Sbjct: 1222 EPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQY-PGQGP 1280

Query: 2032 GLGQVGISPLKPGTVSQQA-LQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAA 2090
              GQ      +PG   QQ   +  +  +  P +   +  + ++ +++ Q       Q   
Sbjct: 1281 PSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ--QEMYNQYGG 1338

Query: 2091 KYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP 2150
             Y+  + +PI GQ   P  +  +Q    PGQ                  +Q  G+    P
Sbjct: 1339 SYSGPDRRPIQGQYPYPYSRERMQG---PGQ------------------IQTHGI----P 1373

Query: 2151 QQQLQPPMGGMSPQAQQMNM--NHNTMPSQFRDILRRQQMMQQQQQQGAGPGIG---PGM 2205
             Q +  P+   S +  Q NM    N MP  +           Q +Q   GP      PGM
Sbjct: 1374 PQMMGGPLQSSSSEGPQQNMWAARNDMPYPY-----------QNRQGPGGPTQAPPYPGM 1422

Query: 2206 ANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLL 2265
               +    P          QR+ H  Q         + Q    + + A            
Sbjct: 1423 NRTDDMMVP---------DQRINHESQW-----PSHVSQRQPYMSSSAS----------- 1457

Query: 2266 QQQMGSPVQPNPMSPQQHMLPN---QAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQP 2322
             Q +  P QP+  +P    LPN   +A SP    + + N +S   +SP  +PS + Q   
Sbjct: 1458 MQPITRPPQPSYQTPPS--LPNHISRAPSPASFQRSLENRMSPS-KSPF-LPSMKMQKVM 1513

Query: 2323 PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGH------FASPDQNSMLSQL 2376
            P    S    P P P  +  + + P PG V A    ++Q          +P+   ++  L
Sbjct: 1514 PTVPTSQVTGPPPQPPPIRREITFP-PGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSL 1572

Query: 2377 ASNPGMANLHGASATDLGLSTDNSDLNSNLSQ 2408
             S     +       ++ L  D++    NLSQ
Sbjct: 1573 KSGLLAESTWALDTINILLYDDSTVATFNLSQ 1604



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 97/404 (24%), Positives = 139/404 (34%), Gaps = 67/404 (16%)

Query: 54  GLTNGGDINQLQTSLGMVQDAASKHKQLS---ELLRSGSSPNLNMGVGGPGQVMASQAQQ 110
           G  N  D+N +Q      Q+  S    LS   + L +G+   L+  V   G   +SQ  Q
Sbjct: 589 GKPNHEDLNLIQ------QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST-SSQGDQ 641

Query: 111 SSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMN-------SPVNQPAM 163
           S+P         +SP +     SP++     GP+  P  S    N       SP + P  
Sbjct: 642 SNPA--------QSPFSPHA--SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGS 691

Query: 164 GMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPL 223
            M         PG  +  +    +    M    G   G Q     NP M   G   T P 
Sbjct: 692 QMPP-----QPPGSQSESSSHPALSQSPMPQERGFMAGTQR----NPQMAQYGPQQTGPS 742

Query: 224 QQGSPQMGGQ-------------TGLRGPQPLKMGMMNNPNPYGSP--YTQNPGQQIGAS 268
               P  GGQ             +G  GPQ  + G   N   Y  P  Y+  P       
Sbjct: 743 MSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGN---YSRPPAYSGVPSASYSGP 799

Query: 269 GLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGM----G 324
           G G+ I     +     P +    AVP G MP+ G Q  P       +TP + GM    G
Sbjct: 800 GPGMGISANNQMHGQ-GP-SQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857

Query: 325 SGAHTADPEKRKLIQQQLVLLLH--AHKCQRREQANGEVRQCNL-----PHCRTMKNVLN 377
            G     P   +  Q+    ++   A+  Q R+ +   + Q  L     P+ + M N  +
Sbjct: 858 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917

Query: 378 HMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAG 421
            M       S   A   SS   +      +  +  + LPLK  G
Sbjct: 918 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADG 961



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 54/198 (27%), Positives = 80/198 (40%), Gaps = 31/198 (15%)

Query: 698 VPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG----QLAQPGAL-------- 745
           +P+Q   R  PQ  ++Q G  + +QPP+ P +     H      Q  +P +L        
Sbjct: 559 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKP---NHEDLNLIQQERPSSLPDLSGSID 615

Query: 746 NPPMGYGPRMQQP-------SNQG-QFLP-QTQF-PSQGMNVTNIPLAPSSGQAPVSQAQ 795
           + P G    +          S+QG Q  P Q+ F P    ++++IP  PS          
Sbjct: 616 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGS 675

Query: 796 MSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPP 855
             S S P+ SP   PGSQ      P  P  +  ++S  P  S++P P       G Q+ P
Sbjct: 676 NQSRSGPI-SPASIPGSQ-----MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 729

Query: 856 ATTIPAPVPTPPAMPPGP 873
                 P  T P+M P P
Sbjct: 730 QMAQYGPQQTGPSMSPHP 747



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 75/360 (20%), Positives = 126/360 (35%), Gaps = 52/360 (14%)

Query: 662  AGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQ--MMPRITPQSGLNQFGQMS 719
            +G +  +  PG  M  PQP  + +     P++ +  +P +   M        + Q+G   
Sbjct: 680  SGPISPASIPGSQM-PPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738

Query: 720  MAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTN 779
               P + P  +P  Q H  ++     N    YGP+M Q   QG +       S+    + 
Sbjct: 739  TG-PSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNY-------SRPPAYSG 790

Query: 780  IPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRT 839
            +P A  SG  P      +++      P  P G+    +   ++P   + QN P P    +
Sbjct: 791  VPSASYSGPGP-GMGISANNQMHGQGPSQPCGA----VPLGRMPSAGM-QNRPFPGNMSS 844

Query: 840  PTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQP 899
             TP  + P +  Q  P    P P     A      + A+      +        P   Q 
Sbjct: 845  MTP--SSPGMSQQGGPGMGPPMPTVNRKAQ---EAAAAVMQAAANSAQSRQGSFPGMNQS 899

Query: 900  SLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSS 959
             L A+ S   P  QP +  S+  +   P                        S  P+  +
Sbjct: 900  GLMASSS---PYSQPMNNSSSLMNTQAP----------------------PYSMAPAMVN 934

Query: 960  TEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTEL 1019
            +   S  +A+     E K+   ++ D  E    QPE  S+         ST T E+ T++
Sbjct: 935  SSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKK-----SSSSTTTGEKITKV 989



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 172/831 (20%), Positives = 261/831 (31%), Gaps = 165/831 (19%)

Query: 88  GSSPNLNMGVGG-PGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNMGMGTSGPNQG 146
           GS+   + G GG  G        Q SPG+G+++S   +     G   P        PN  
Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236

Query: 147 PTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQ 206
                G      ++P  G   G   G   G    G G G        G++ A        
Sbjct: 237 CNHYPG-----YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291

Query: 207 YPNPGMGSAG------NLLTEPLQQGSPQM-----GGQTGL------------------- 236
               G G  G       +L+ P QQG   M     GG   L                   
Sbjct: 292 AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351

Query: 237 ---RGPQPLKMGMMNNPNP-----------YGSPYTQNP-----------------GQQI 265
               G  P    ++ +P+P           Y SP    P                 GQQ 
Sbjct: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411

Query: 266 GAS-GLGLQIQTKTVLSNNLSPFAMDKK---AVPGGGMPNMGQQPAPQVQQPGLVTPVAQ 321
            A  GLG  +  +   ++     A  +      PG   P MG+     +    +  P   
Sbjct: 412 AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLY 471

Query: 322 GMGSGAHTADPEKRKLI--------QQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMK 373
           GMGS  H+   +              Q+  + +          A  +  Q  +P     +
Sbjct: 472 GMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR--TPGAMAGMQYPQQQMPPQYGQQ 529

Query: 374 NVLNHMTHCQSG------KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQ 427
            V     +CQ G      +  Q  H     Q +   ++  R+     +  +  G  R+Q 
Sbjct: 530 GVSG---YCQQGQQPYYSQQPQPPHLPPQAQYLPS-QSQQRYQPQQDMSQEGYG-TRSQP 584

Query: 428 PILTGAP-------VGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERA---YAALGLPYQV 477
           P+  G P       +    PSSL     S  +L T ++   SS   A    ++ G     
Sbjct: 585 PLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNP 644

Query: 478 NQMPTQPQVQAK-NQQNQQPGQSPQGMRPMSNMS----ASPMGVNGG-VGVQTPSLLSDS 531
            Q P  P      +     P  SP G    SN S     SP  + G  +  Q P   S+S
Sbjct: 645 AQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSES 704

Query: 532 MLHSAINSQNPMMSENASVPSLGPMPTAAQ--PSTTGIRKQWHEDITQDLRNHLVHKLVQ 589
             H A+ SQ+PM  E   +      P  AQ  P  TG                       
Sbjct: 705 SSHPAL-SQSPMPQERGFMAGTQRNPQMAQYGPQQTG----------------------P 741

Query: 590 AIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRR 649
           ++ P P P       + +            ++ +N+   Y   +++  Y  Q        
Sbjct: 742 SMSPHPSPGGQMHAGISS------------FQQSNSSGTYGPQMSQ--YGPQGNY----- 782

Query: 650 TRLQKQNMLPNAA------GMVPVSMNPGPNMGQPQP-GMTSNGPLPDPSMIRGSVPNQM 702
           +R    + +P+A+      GM   + N     G  QP G    G +P   M     P  M
Sbjct: 783 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 703 MPRITPQSGLNQFGQMSMAQP-PIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQ 761
                   G++Q G   M  P P V R+          A   +     G  P M Q    
Sbjct: 843 SSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLM 902

Query: 762 GQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVN-SPIMPPG 811
               P +Q  +   ++ N    P S    ++ A ++SS+  V  + +M PG
Sbjct: 903 ASSSPYSQPMNNSSSLMNTQAPPYS----MAPAMVNSSAASVGLADMMSPG 949



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 135/634 (21%), Positives = 198/634 (31%), Gaps = 140/634 (22%)

Query: 1846 GLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQV 1905
            G+PS + + P    G         Q  SQP    P    P         P +       +
Sbjct: 790  GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS----M 845

Query: 1906 TPPTPPQTAQ------PPLPGPPPAAVEMAMQIQRAAETQRQ--------------MAHV 1945
            TP +P  + Q      PP+P     A E A  + +AA    Q              MA  
Sbjct: 846  TPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS 905

Query: 1946 QIFQRPIQH-------QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQG 1998
              + +P+ +       Q PP + MAP  +N    + G +  + PG     +  +    + 
Sbjct: 906  SPYSQPMNNSSSLMNTQAPPYS-MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEE 964

Query: 1999 GLPQPQ--------------------QLQSGMPRPAMMS-----VAQHGQPLNMAPQPGL 2033
            G PQP+                    +L +   R   +      + + G P++  P  G 
Sbjct: 965  GTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGK 1024

Query: 2034 GQV-------------GISPLKPGTVSQQALQNL-LRTLRSPSSPLQQQQVLSILHANPQ 2079
              +             G++ +      ++   NL + T  S +S L++Q +        Q
Sbjct: 1025 KPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYI--------Q 1076

Query: 2080 LLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAM-----QNMN 2134
             L AF            P P     G  + QP LQPP+ P   G    P        N  
Sbjct: 1077 YLFAF---ECKIERGEEPPPEVFSTGDTKKQPKLQPPS-PANSGSLQGPQTPQSTGSNSM 1132

Query: 2135 PMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF--RDILRRQQMMQQQ 2192
                G  +   P   P  Q+ P  GG S      +   +   S F  R+ +      QQ 
Sbjct: 1133 AEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQG 1192

Query: 2193 QQQGAGPGIGPGMANHNQF---QQPQGVGYPPQQQQRMQHHMQQ----------MQQGNM 2239
                   G  P   N + F   ++  G   P   Q +M +   Q          M    M
Sbjct: 1193 MSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGM 1252

Query: 2240 GQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPV-QPNPMSPQQHMLPNQAQ-SPHLQGQ 2297
            GQ  Q P   GA      + Y Q+   Q  G P  QP     Q  + P Q     H+ G 
Sbjct: 1253 GQRQQFP--YGASYDRRHEPYGQQYPGQ--GPPSGQPPYGGHQPGLYPQQPNYKRHMDGM 1308

Query: 2298 QIP------------------NSLSNQVRSPQPVPSPRP-QSQPPHSSPSPRMQ--PQPS 2336
              P                    + NQ       P  RP Q Q P+     RMQ   Q  
Sbjct: 1309 YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQ 1368

Query: 2337 PHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQN 2370
             H + PQ              P++      P QN
Sbjct: 1369 THGIPPQ----------MMGGPLQSSSSEGPQQN 1392



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 79/318 (24%), Positives = 103/318 (32%), Gaps = 71/318 (22%)

Query: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL 2154
            S+P   P  P  PQ Q         GQQ        ++M    A    A  P     QQ 
Sbjct: 383  SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYA----AASPAWAAAQQR 438

Query: 2155 QPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP 2214
              P   MSP      M  +        +++R Q+             G G   H+Q QQ 
Sbjct: 439  SHP--AMSPGTPGPTMGRSQGSPMDPMVMKRPQLY------------GMGSNPHSQPQQS 484

Query: 2215 Q---GVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGS 2271
                G  Y P   QR    +Q          G+ P   GA AG                 
Sbjct: 485  SPYPGGSYGPPGPQRYPIGIQ----------GRTP---GAMAGMQY-------------- 517

Query: 2272 PVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRM 2331
                    PQQ M P         GQQ  +    Q    QP  S +PQ  PPH  P  + 
Sbjct: 518  --------PQQQMPPQY-------GQQGVSGYCQQ--GQQPYYSQQPQ--PPHLPPQAQY 558

Query: 2332 QPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASAT 2391
             P  S     PQ      G       P+  G     D N +  +  S+  + +L G S  
Sbjct: 559  LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS--LPDLSG-SID 615

Query: 2392 DLGLSTDNSDLNSNLSQS 2409
            DL   T+ + L+S +S S
Sbjct: 616  DLPTGTE-ATLSSAVSAS 632



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 44/198 (22%), Positives = 78/198 (39%), Gaps = 40/198 (20%)

Query: 629 YYHLLAEKIYKIQKELEEKRRTRLQKQ---------NMLPNAAGMVPVSMNPGPNMGQPQ 679
           ++H L +++ + Q++ +++++ + Q+Q         N L  A G  P    PGP+M QPQ
Sbjct: 44  HHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAP---QPGPDMEQPQ 100

Query: 680 PGMTSNG-------PLPDPSMIRGSVPNQMMPRITPQSGLNQ----FGQMSMAQPPIV-- 726
            G   +        P   P + +    +   P++   +G        G +   QPP+   
Sbjct: 101 HGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP 160

Query: 727 -----PRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIP 781
                P   P   ++   A P +  P    GP   Q   Q          S GM + +  
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ---------QSPGMGMMHSA 211

Query: 782 LAPSSGQAPVSQAQMSSS 799
            A ++G AP S   + +S
Sbjct: 212 SAAAAG-APGSMDPLQNS 228



 Score = 38.5 bits (88), Expect = 0.081
 Identities = 83/407 (20%), Positives = 122/407 (29%), Gaps = 41/407 (10%)

Query: 670  NPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQ 729
            N  P+   P        P P      GS P    P   P        Q + A      +Q
Sbjct: 351  NQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQ 410

Query: 730  TPPLQHHGQL--AQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSG 787
                   G+   AQ  A +P      +   P+      P T  P+ G +  + P+ P   
Sbjct: 411  AAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMS----PGTPGPTMGRSQGS-PMDPMVM 465

Query: 788  QAPVSQAQMSSS-SCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP 846
            + P      S+  S P  S   P GS G     PQ     +   +P  +          P
Sbjct: 466  KRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAGMQYPQQQMP 523

Query: 847  PSIGAQ------QPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS 900
            P  G Q      Q       +  P PP +PP  Q        R  P    +Q     +  
Sbjct: 524  PQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQ 583

Query: 901  LPAAPSADQPQQQPRSQQSTAASVPTPTAPL--LPPQPATPLSQP-----AVSIEGQVSN 953
             P AP     +     QQ   +S+P  +  +  LP      LS       + S +G  SN
Sbjct: 584  PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643

Query: 954  P----------------PSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQ--PEPADTQPE 995
            P                P   S       +   Q        A +   Q  P+P  +Q E
Sbjct: 644  PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703

Query: 996  DISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042
              S   +    M         T+   ++ +   Q +  +    P+PG
Sbjct: 704  SSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 68/279 (24%), Positives = 89/279 (31%), Gaps = 75/279 (26%)

Query: 8   PGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTS 67
           P PP ++    S PALS S                +P       E G   G   N     
Sbjct: 695 PQPPGSQSESSSHPALSQS---------------PMPQ------ERGFMAGTQRNPQMAQ 733

Query: 68  LGMVQDAAS----------KHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGL 117
            G  Q   S           H  +S   +S SS     G  GP      Q  Q  P    
Sbjct: 734 YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSS-----GTYGP------QMSQYGPQGNY 782

Query: 118 INSMVKSPMTQAGLTSPNMGMGTSGPN----QGPTQ-----------STGMMNSPV--NQ 160
                 S +  A  + P  GMG S  N    QGP+Q           S GM N P   N 
Sbjct: 783 SRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNM 842

Query: 161 PAM-----GMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSA 215
            +M     GM+     GM P M             VM  +  + + RQ      PGM  +
Sbjct: 843 SSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG---SFPGMNQS 899

Query: 216 GNL-----LTEPLQQGSPQMGGQTGLRGPQPLKMGMMNN 249
           G +      ++P+   S  M  Q     P  +   M+N+
Sbjct: 900 GLMASSSPYSQPMNNSSSLMNTQA---PPYSMAPAMVNS 935



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 45/190 (23%), Positives = 62/190 (32%), Gaps = 29/190 (15%)

Query: 2209 NQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQ 2268
            NQFQQ Q      QQQQ+ Q H         G  G  PQ      G  ++  Q    +  
Sbjct: 53   NQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQ-----PGPDMEQPQHGGAKDS 107

Query: 2269 MGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSP- 2327
                    P  P      ++  +P   G+          R   P        QPP + P 
Sbjct: 108  AAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGG------RYEHPGLGALGTQQPPVAVPG 161

Query: 2328 ---SPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMAN 2384
                P   P+ + ++ S   +S  PG    +A P    H               +PGM  
Sbjct: 162  GGGGPAAVPEFNNYYGSAAPASGGPG---GRAGPCFDQHGGQ-----------QSPGMGM 207

Query: 2385 LHGASATDLG 2394
            +H ASA   G
Sbjct: 208  MHSASAAAAG 217


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 138/541 (25%), Positives = 177/541 (32%), Gaps = 72/541 (13%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            Q G   P P   T P  QQ   P  PQ        P  S  P        G         
Sbjct: 386  QMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445

Query: 1904 QVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963
              T   PP   Q P             Q  +     +Q  H Q  Q P   Q P  TP A
Sbjct: 446  SYTQQIPPYGQQGP---------SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496

Query: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQ-QQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG 2022
                   P ++ P   L+    P   Q  QPP  Q   P P Q  +    P   S   + 
Sbjct: 497  QPSYQQQPQSQPP--QLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP--QSQPPYS 552

Query: 2023 QPLNMAP-------QPGLGQVGISPLKPGTVSQQALQNLLRTLR-SPSSPLQQQQVLSIL 2074
            QP   +P       QP    +      P   SQQ+ Q      R  P   L Q    S  
Sbjct: 553  QPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612

Query: 2075 HANPQLLAAFIKQRAAKYA-NSNPQPIPGQPG----MPQG-----QPGLQPPTMPGQQGV 2124
             + P + ++   Q     +  S P  +P   G    +P G      PG+    +   QG 
Sbjct: 613  SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGE 672

Query: 2125 HSNPAMQNMNPMQA----GVQ-RAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179
             SNPA    +P  +    G++  +  P   P    Q   G +SP A   N      PS  
Sbjct: 673  QSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732

Query: 2180 RDILRRQQMMQQQQQQGAG-PGIGPGMANHNQFQQPQ-GVGYPPQQQQRMQHH--MQQMQ 2235
             D +    M Q    Q  G     P M    Q+  PQ G    P+Q    Q H  M   Q
Sbjct: 733  SDSIMHPSMNQSSIAQDRGYMQRNPQMP---QYSSPQPGSALSPRQPSGGQIHTGMGSYQ 789

Query: 2236 QGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPN-QAQSPHL 2294
            Q +MG  G  PQ  G + G             Q G P QPN      + LPN    S  +
Sbjct: 790  QNSMGSYG--PQ--GGQYG------------PQGGYPRQPN-----YNALPNANYPSAGM 828

Query: 2295 QGQQIPNSLSNQVRSPQPVP--SPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSS---PHP 2349
             G   P     Q+     +P     P  +  H+S   R    P+  ++ PQ  S   P P
Sbjct: 829  AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPY-GPNMANMPPQVGSGMCPPP 887

Query: 2350 G 2350
            G
Sbjct: 888  G 888



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 103/416 (24%), Positives = 137/416 (32%), Gaps = 96/416 (23%)

Query: 680  PGMTSNGPLPDPSMIRGSVPNQMMPRITPQ--SGLNQFGQMSMAQPPIVPRQTPPLQHHG 737
            PG +  G  P     + S P   M ++ PQ   G N + Q     PP     + P Q HG
Sbjct: 364  PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQ--GPP-----SGPQQGHG 416

Query: 738  QLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMS 797
               QP     P  Y   MQ                                    +AQ +
Sbjct: 417  YPGQPYGSQTPQRYPMTMQ-----------------------------------GRAQSA 441

Query: 798  SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857
                     I P G QG   +  Q   P  +Q SP P                 QQPP +
Sbjct: 442  MGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHP---------------QQQQPPYS 486

Query: 858  TIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ 917
              P P  TP A P   Q     PP  Q+  PP +Q     QPS P  P    P   P SQ
Sbjct: 487  QQP-PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ-----QPSQP--PHQQSPAPYP-SQ 537

Query: 918  QSTAASVPTPTAPLLPPQPATPL-----SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ- 971
            QST    P    P   PQ  +P       QPA S   Q +  P   S +    A ++++ 
Sbjct: 538  QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597

Query: 972  -PSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQP 1030
             P QE+  ++        P+ T     S+   ED  +          +L   I   +D P
Sbjct: 598  PPPQELSQDSFGSQASSAPSMTS----SKGGQEDMNLSLQSRPSSLPDLSGSI---DDLP 650

Query: 1031 STSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
                T+ + +PG S   I   +              + +P   PF     P L GI
Sbjct: 651  --MGTEGALSPGVSTSGISSSQG------------EQSNPAQSPFSPHTSPHLPGI 692



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 137/532 (25%), Positives = 182/532 (34%), Gaps = 120/532 (22%)

Query: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMA 1929
            QP  QP P+P  S     P+T  +   S  +  G + PPTP  T    +P  P  +   +
Sbjct: 1127 QPKIQP-PSPAGSGSMQGPQTPQSTSSSMAEG-GDLKPPTPASTPHSQIPPLPGMSRSNS 1184

Query: 1930 MQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGM 1989
            + IQ A            FQ+  ++ M P     P  MN   M    S   EP   P G 
Sbjct: 1185 VGIQDAFNDGSDST----FQK--RNSMTPNPGYQP-SMNTSDMMGRMS--YEPNKDPYGS 1235

Query: 1990 QQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLK------- 2042
             ++ P S   +   Q    GM           G P + A  PGLG V + P +       
Sbjct: 1236 MRKAPGSDPFMSSGQGPNGGM-----------GDPYSRAAGPGLGNVAMGPRQHYPYGGP 1284

Query: 2043 ------------PGTVSQQALQ-NLLRT-----LRSPSS--PLQQQQVLSILHANPQLLA 2082
                         G +S  A Q NL+ +     + SPS   P QQQQ             
Sbjct: 1285 YDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQ------------ 1332

Query: 2083 AFIKQRAAKYANSNPQPIPGQPGMPQGQP-GLQPPTMPGQQ---------GVHSNPAMQN 2132
               +QR   Y N          G P G P   Q  TM  QQ         G +  PA ++
Sbjct: 1333 ---QQRHDSYGNQF-----STQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRH 1384

Query: 2133 MNPM--------QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILR 2184
               M        Q   Q+  LP  QPQ   Q      SPQ    N   N  P+       
Sbjct: 1385 EGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATE 1444

Query: 2185 RQQMMQQQQQQ----GAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMG 2240
            R+     Q Q     G      P   N  Q   PQ +G P      +Q   +  QQG M 
Sbjct: 1445 RRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGP------IQASAEVAQQGTMW 1498

Query: 2241 QIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQP--NPMSPQQHMLPNQAQSPHLQGQQ 2298
            Q            G +   Y     Q    +P  P  + ++    ML    ++ H +G  
Sbjct: 1499 Q------------GRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANH-EGSW 1545

Query: 2299 IPNSLSNQVRSPQ-PVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHP 2349
              +        P  PVP   P ++PP S+     QP PS  +  PQ SSP P
Sbjct: 1546 PSHGTRQPPYGPSAPVP---PMTRPPPSN----YQPPPSMQNHIPQVSSPAP 1590



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 240/1144 (20%), Positives = 392/1144 (34%), Gaps = 202/1144 (17%)

Query: 19   SSPALSASASDGTDFG--------SLFDLEHDLPDELINSTELGLTNGGDINQLQTSLGM 70
            S+P++++S     D          SL DL   + D+L   TE  L+ G   + + +S G 
Sbjct: 614  SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSI-DDLPMGTEGALSPGVSTSGISSSQGE 672

Query: 71   VQDAA----SKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPM 126
              + A    S H         G SP+    VG P  V  S++   SP     N M   P 
Sbjct: 673  QSNPAQSPFSPHTSPHLPGIRGPSPS---PVGSPASVAQSRSGPLSPAAVPGNQMPPRPP 729

Query: 127  T--QAGLTSPNMGMGTSGPNQGPTQSTGMM---NSPV-------NQPAMG-MNTGMNAGM 173
            +     +  P+M   +   ++G  Q    M   +SP         QP+ G ++TGM +  
Sbjct: 730  SGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQ 789

Query: 174  NPGMLAAG------NGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQGS 227
               M + G        QG  P Q    ++       N  YP+ GM    N    P+  G 
Sbjct: 790  QNSMGSYGPQGGQYGPQGGYPRQPNYNAL------PNANYPSAGMAGGIN----PMGAGG 839

Query: 228  PQMGGQTGLRGPQPLKMGMMNNPN----PYGSPYTQNPGQQIGAS------GLGLQIQTK 277
             QM GQ G+     L  G M++ +    PYG P   N   Q+G+       G+  + Q +
Sbjct: 840  -QMHGQPGIPPYGTLPPGRMSHASMGNRPYG-PNMANMPPQVGSGMCPPPGGMNRKTQ-E 896

Query: 278  TVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQP---------GLVTPVAQGMGSGAH 328
            T ++ +++  ++  +     G PNM Q        P         G++ P       G  
Sbjct: 897  TAVAMHVAANSIQNRPP---GYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGT 953

Query: 329  TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSC 388
             A+         +++ L    K     + N +         ++ K+  +  T+ +  K  
Sbjct: 954  MANNSAGMAASPEMMGLGDV-KLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLY 1012

Query: 389  QVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPSSLGVGQ- 447
            ++      +  +  +   T         L   G K      L  +   +G  + +   + 
Sbjct: 1013 ELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKK 1072

Query: 448  --QSAPNLST-VSQIDPSSIERAYA----ALGLPYQVNQMPTQPQVQAKNQQNQQPGQSP 500
              + A NL+   S    SS+++ Y     A     +  + P      A + +  QP   P
Sbjct: 1073 WRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQP 1132

Query: 501  QGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSA-INSQNPMMSENASVPSLGPMPTA 559
                       SP G     G QTP   S SM     +    P  + ++ +P   P+P  
Sbjct: 1133 P----------SPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIP---PLPGM 1179

Query: 560  AQPSTTGIRKQWHE--DITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 617
            ++ ++ GI+  +++  D T   RN +          TP+P                    
Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSM----------TPNPG------------------- 1210

Query: 618  DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVP-VSMNPGPNMG 676
              Y+ + N ++   ++    Y+  K+     R           A G  P +S   GPN G
Sbjct: 1211 --YQPSMNTSD---MMGRMSYEPNKDPYGSMR----------KAPGSDPFMSSGQGPNGG 1255

Query: 677  QPQPGMTSNGP-LPDPSMIRGSVPNQMMP------RITPQSGLNQFGQMSMAQPPIVPRQ 729
               P   + GP L + +M     P Q  P      R+  + G+   G MS   P   P  
Sbjct: 1256 MGDPYSRAAGPGLGNVAM----GPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQ--PNL 1309

Query: 730  TPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQA 789
             P     G  +       P  Y P+ QQ   Q       QF +QG   +  P    S Q 
Sbjct: 1310 MPSNPDSGMYS-------PSRYPPQQQQQQQQRHDSYGNQFSTQG-TPSGSPFP--SQQT 1359

Query: 790  PVSQAQMSSSSCPVNSPIMPP-----------------GSQGSHIHCPQLPQPALHQNSP 832
             + Q Q  +   P++    PP                 G        P  PQPA  Q + 
Sbjct: 1360 TMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAA 1419

Query: 833  SPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPR-QTPTPPTT 891
             P P +     +          PAT   A    P     GPQ+Q      R +   PP T
Sbjct: 1420 QPSPQQDVYNQY------GNAYPATATAATERRPAG---GPQNQFPFQFGRDRVSAPPGT 1470

Query: 892  QLPQQVQPSLPAAP---SADQPQQ----QPRSQQST--AASVPTPTAPLLPPQPATPLSQ 942
               Q + P +   P   SA+  QQ    Q R+  +   A    T +AP  P       + 
Sbjct: 1471 NAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTD 1530

Query: 943  PAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKV 1002
              +  + + ++  S  S            P   +          P         +S    
Sbjct: 1531 EMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAP 1590

Query: 1003 EDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQS---KKKIFKPEELRQALM 1059
                ME+  +  +S  L + +K ++  P   A+  +PAP Q    ++ I  P    +A  
Sbjct: 1591 LPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQ 1650

Query: 1060 PTLE 1063
            P L+
Sbjct: 1651 PVLK 1654



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 137/566 (24%), Positives = 175/566 (30%), Gaps = 87/566 (15%)

Query: 1875 PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQR 1934
            P+P   N++    P     G  S G  A       PP +A   LP   P A        R
Sbjct: 109  PRPALNNNLTE--PPGGGGGGSSDGVGA-------PPHSAAAALP---PPAYGFGQPYGR 156

Query: 1935 AAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP- 1993
            +       A     Q+    Q P +  +            G  G LEP  GP        
Sbjct: 157  SPSAVAAAAAAVFHQQHGGQQSPGLAALQS----------GGGGGLEPYAGPQQNSHDHG 206

Query: 1994 -PWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQ 2052
             P  Q     P +     P PA    +  G        PG G    +  KP   S  +  
Sbjct: 207  FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGT------PGSGAAAAAGSKPPPSSSASAS 260

Query: 2053 NLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPG 2112
                   S SS   QQ+  ++    P        Q  A    +     P      QG PG
Sbjct: 261  -------SSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG 313

Query: 2113 LQPPTMPGQQGVHSNPA---MQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN 2169
                  P   G    PA    Q      A    A       Q+    PM   S       
Sbjct: 314  GDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP 373

Query: 2170 MNHNTMPSQFRDILRRQQMMQ----QQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQ 2225
            +     PS   D + + +           Q  GP  GP    H    QP G   P +   
Sbjct: 374  LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-QQGHGYPGQPYGSQTPQRYPM 432

Query: 2226 RMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHML 2285
             MQ   Q    G +    Q+P           Q  Q     QQ   P Q  P   QQ   
Sbjct: 433  TMQGRAQSAM-GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQP-- 489

Query: 2286 PNQAQSPHLQG--QQIPNSLSNQVRSPQPVPSPRPQSQPPHS-SPSP--------RMQPQ 2334
               +Q+PH Q   QQ P S   Q++S QP  S +P SQPPH  SP+P        +  PQ
Sbjct: 490  --PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQ 546

Query: 2335 PSPHHVSPQTSSPH---------------------PGLVAAQANPMEQGHFASP---DQN 2370
              P +  PQ  SP+                     P    +Q     Q  F  P    Q+
Sbjct: 547  SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606

Query: 2371 SMLSQLASNPGMANLHGASATDLGLS 2396
            S  SQ +S P M +  G    D+ LS
Sbjct: 607  SFGSQASSAPSMTSSKGGQ-EDMNLS 631



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 132/552 (23%), Positives = 172/552 (31%), Gaps = 74/552 (13%)

Query: 1869 PQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG-PPPAAVE 1927
            PQ  S     P +    Y P   A  P +   A       TP   A       PPP++  
Sbjct: 198  PQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSA 257

Query: 1928 MAMQIQRAAETQR--QMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMG 1985
             A     +   QR   M              P  TP     +  P   RG  G+  PG  
Sbjct: 258  SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGY--PGGD 315

Query: 1986 PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGT 2045
             +G  Q     +G      Q        A  + A  G                +P+ PG+
Sbjct: 316  YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH---------APMSPGS 366

Query: 2046 VSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPG 2105
             S    Q L RT + PSSP+ Q   +      PQ           +   S PQ   G PG
Sbjct: 367  -SGGGGQPLARTPQ-PSSPMDQMGKM-----RPQPYGGTNPYSQQQGPPSGPQQGHGYPG 419

Query: 2106 MPQGQ--PGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP----QQQLQPPMG 2159
             P G   P   P TM G+       A   M  +    Q     QQ P    QQ   P   
Sbjct: 420  QPYGSQTPQRYPMTMQGR-------AQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472

Query: 2160 GMSPQAQQMNMNHNTMPSQ----FRDILRRQQMMQQQQQQGAGPGIG--PGMANHNQFQQ 2213
              SP  QQ    ++  P       +   ++Q   Q  Q Q + P     P    H Q   
Sbjct: 473  QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA 532

Query: 2214 PQGVGYPPQQQQRMQHHMQQ----MQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQM 2269
            P    YP QQ    QH   Q      Q       Q PQ       +   AY Q   QQ  
Sbjct: 533  P----YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ 588

Query: 2270 GSPVQ----PNPMSPQQHMLPNQAQSP-------------HLQGQQIPNSLSNQVRSPQP 2312
             +       P P    Q    +QA S              +L  Q  P+SL +   S   
Sbjct: 589  QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD 648

Query: 2313 VP-------SPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFA 2365
            +P       SP   +    SS   +  P  SP   SP TS   PG+     +P+      
Sbjct: 649  LPMGTEGALSPGVSTSGISSSQGEQSNPAQSPF--SPHTSPHLPGIRGPSPSPVGSPASV 706

Query: 2366 SPDQNSMLSQLA 2377
            +  ++  LS  A
Sbjct: 707  AQSRSGPLSPAA 718



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 75/300 (25%), Positives = 107/300 (35%), Gaps = 34/300 (11%)

Query: 666 PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ--------SGLNQFGQ 717
           P S  P       QP          P +     P    P   P         S  +   Q
Sbjct: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 718 MSMAQPPIVP--RQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFP---- 771
              +QPP      Q+P  Q   Q   P  L+    Y P+ Q   +Q     Q +FP    
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY-PQPQSQQSQQTAYSQQRFPPPQE 602

Query: 772 -SQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
            SQ    +    APS   +   Q  M+ S    + P   P   GS    P   + AL   
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSL--QSRPSSLPDLSGSIDDLPMGTEGALSPG 660

Query: 831 -SPSPV---------PSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPP---GPQSQA 877
            S S +         P+++P   HT P +   + P+   P+PV +P ++     GP S A
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS---PSPVGSPASVAQSRSGPLSPA 717

Query: 878 LHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA 937
             P  +  P PP+ Q    + PS+  +  A       R+ Q    S P P + L P QP+
Sbjct: 718 AVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPS 777



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 103/435 (23%), Positives = 142/435 (32%), Gaps = 65/435 (14%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYL---PRTQAAGPVSQGK 1900
            QQ    P   +P     QQ TT Q PQ  SQP  + P +  PY    P+  A   +SQ  
Sbjct: 520  QQPSQPPHQQSPAPYPSQQSTTQQHPQ--SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577

Query: 1901 AAGQVTPPTPPQTAQPPLPGPPPAAVEM---AMQIQRAAETQRQMAHVQIFQRPIQHQMP 1957
            A  Q       QTA      PPP  +       Q   A          +     +Q + P
Sbjct: 578  AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR-P 636

Query: 1958 PMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ---------QPPWSQGGLPQPQQLQS 2008
               P     ++  PM  G  G L PG+  +G+           Q P+S    P    ++ 
Sbjct: 637  SSLPDLSGSIDDLPM--GTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG 694

Query: 2009 GMPRP--AMMSVAQ-HGQPLN--------MAPQPGLGQVGISPLKPGTVSQQALQNLLRT 2057
              P P  +  SVAQ    PL+        M P+P  GQ   S + P        Q+    
Sbjct: 695  PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSD-SIMHPSMNQSSIAQDRGYM 753

Query: 2058 LRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGM--PQGQPGLQP 2115
             R+P  P           +  Q     I      Y  ++      Q G   PQG    QP
Sbjct: 754  QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813

Query: 2116 PTMPGQQGVHSNPAMQN-MNPMQAGVQRAGLPQQQPQQQLQP------------------ 2156
                     + +  M   +NPM AG Q  G P   P   L P                  
Sbjct: 814  NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMA 873

Query: 2157 ------------PMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPG 2204
                        P GGM+ + Q+  +  +   +  ++       M Q    G GP  G G
Sbjct: 874  NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQG 933

Query: 2205 MANHNQFQQPQGVGY 2219
            + +      PQG  Y
Sbjct: 934  INSMAGMINPQGPPY 948



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 138/626 (22%), Positives = 208/626 (33%), Gaps = 107/626 (17%)

Query: 434  PVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPT---QPQVQAKN 490
            P G   PS  G GQQ            P   +  Y+        +  P+   QPQ Q   
Sbjct: 453  PYGQQGPS--GYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510

Query: 491  QQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASV 550
             Q+ QP  S Q  +P    S +P           PS  S +  H    SQ P     A  
Sbjct: 511  LQSSQPPYSQQPSQPPHQQSPAPY----------PSQQSTTQQHP--QSQPPYSQPQAQS 558

Query: 551  PSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVA 610
            P     P    PST                        QA +P P        +     A
Sbjct: 559  PYQQQQPQQPAPSTLS---------------------QQAAYPQP------QSQQSQQTA 591

Query: 611  YARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMV---PV 667
            Y+++      E + +        A  +   +   E+   +   + + LP+ +G +   P+
Sbjct: 592  YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM 651

Query: 668  ----SMNPGPNMG--------QPQPGMTSNGPLPDPSM--IRGSVPNQM-MPRITPQSGL 712
                +++PG +          Q  P  +   P   P +  IRG  P+ +  P    QS  
Sbjct: 652  GTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS-- 709

Query: 713  NQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPS--NQGQFLPQTQF 770
             + G +S A  P    Q PP    GQ      ++P M      Q      +   +PQ   
Sbjct: 710  -RSGPLSPAAVP--GNQMPPRPPSGQ--SDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSS 764

Query: 771  PSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
            P  G  ++  P  PS GQ          +S     P    G  G     P+  QP  +  
Sbjct: 765  PQPGSALS--PRQPSGGQIHTGMGSYQQNSMGSYGP--QGGQYGPQGGYPR--QPNYNAL 818

Query: 831  SPSPVPSRTPTPHHTPPSIGAQQ------PPATTIPAPVPTPPAM---PPGPQSQALHPP 881
              +  PS        P   G Q       PP  T+P    +  +M   P GP    + P 
Sbjct: 819  PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878

Query: 882  PRQTPTPPTTQLPQQVQPSLPAA-PSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPL 940
                  PP   + ++ Q +  A   +A+  Q +P    +        T P        P 
Sbjct: 879  VGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGP--------PY 930

Query: 941  SQPAVSIEGQVS--NPP-STSSTEVNSQAIAEKQPSQ----EVKMEAKMEVDQPEPADTQ 993
             Q   S+ G ++   PP S   T  N+ A     P      +VK+    +++    AD  
Sbjct: 931  GQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMN--NKADGT 988

Query: 994  PEDISESKVEDCKMESTETEERSTEL 1019
            P+  S+SK       ST T E+ T+L
Sbjct: 989  PKTESKSKKSS---SSTTTNEKITKL 1011



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 119/508 (23%), Positives = 170/508 (33%), Gaps = 94/508 (18%)

Query: 137 GMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSI 196
           G GT  P   PT +  ++ SP +        G +    P    AG G   M +Q    + 
Sbjct: 283 GGGTPQPTATPTLNQ-LLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341

Query: 197 GAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPL----KMGMMNNPNP 252
            A              G+       P+  GS   GGQ   R PQP     +MG M  P P
Sbjct: 342 AAAAAAA------ASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM-RPQP 394

Query: 253 YG--SPYTQNPGQQIG-ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGG-------MPNM 302
           YG  +PY+Q  G   G   G G   Q     +    P  M  +A    G       +P  
Sbjct: 395 YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454

Query: 303 GQQ------------------PAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVL 344
           GQQ                  P PQ QQP    P +Q   S    A P  ++  Q Q   
Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQP----PYSQQPPSQTPHAQPSYQQQPQSQPPQ 510

Query: 345 LLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNH------------MTHCQSGKSCQVAH 392
           L  +     ++ +    +Q   P+         H             +  Q  +  Q A 
Sbjct: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 393 CASSRQII-----SHWKNCT-----RHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPS- 441
              S+Q       S     T     R   P  L   + G + +  P +T +  G  + + 
Sbjct: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630

Query: 442 SLGVGQQSAPNLS---------TVSQIDP----SSIERAYAALGLPYQVNQMP-TQPQVQ 487
           SL     S P+LS         T   + P    S I  +      P Q    P T P + 
Sbjct: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690

Query: 488 AKNQQNQQPGQSPQGMRPMSNMSASPMGVNGG-VGVQTPSLLSDSMLHSAIN-------- 538
                +  P  SP  +    +   SP  V G  +  + PS  SDS++H ++N        
Sbjct: 691 GIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDR 750

Query: 539 ---SQNPMMSENASVPSLGPMPTAAQPS 563
               +NP M + +S P  G   +  QPS
Sbjct: 751 GYMQRNPQMPQYSS-PQPGSALSPRQPS 777



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 66/282 (23%), Positives = 95/282 (33%), Gaps = 50/282 (17%)

Query: 677  QPQPGMTSNGPLPDPSM-----------IRGSVPNQMMPRITPQSGLN-QFGQMSMAQPP 724
            QPQP        P P                +   +  P   PQ+    QFG+  ++ PP
Sbjct: 1409 QPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPP 1468

Query: 725  IVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAP 784
                        G  AQ     PP   G  +Q  +   Q    T +  +     N     
Sbjct: 1469 ------------GTNAQQNM--PPQMMGGPIQASAEVAQ--QGTMWQGRNDMTYNYANRQ 1512

Query: 785  SSGQAPVSQA----QMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTP 840
            S+G AP   A      +      +      GS  SH       QP    ++P P  +R P
Sbjct: 1513 STGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSH----GTRQPPYGPSAPVPPMTRPP 1568

Query: 841  TPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGP-QSQALHPPPRQ----TPTPPTTQLPQ 895
              ++ PP       P  + PAP+P P      P +S  LH   +      P P +   P 
Sbjct: 1569 PSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPA 1628

Query: 896  QVQPSL--------PAAPSADQPQQQPRSQQSTAASVPTPTA 929
             VQP +        P +  A QP  + R ++ T   + TP A
Sbjct: 1629 PVQPPMIRRDITFPPGSVEATQPVLKQR-RRLTMKDIGTPEA 1669



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 68/284 (23%), Positives = 95/284 (33%), Gaps = 64/284 (22%)

Query: 1816 QQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQ- 1874
            QQ     QQ Q  +R M           +  + S   +T      QQ   P  PQP SQ 
Sbjct: 1357 QQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQ 1416

Query: 1875 --PQPTP------------PNSMPPYLPRTQAAGPVSQ-----GKAAGQVTPPTPPQTAQ 1915
               QP+P            P +      R  A GP +Q     G+      P T  Q   
Sbjct: 1417 QAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNM 1476

Query: 1916 PP--LPGPPPAAVEMAMQ---IQRAAETQRQMAHVQIF----QRPIQH------------ 1954
            PP  + GP  A+ E+A Q    Q   +     A+ Q      Q P  H            
Sbjct: 1477 PPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTD 1536

Query: 1955 --------------QMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGL 2000
                          + PP  P AP+    PPMTR P  + +P   P  MQ   P      
Sbjct: 1537 QRANHEGSWPSHGTRQPPYGPSAPV----PPMTRPPPSNYQP---PPSMQNHIPQVSSPA 1589

Query: 2001 PQPQQLQSGMPRPAMMSVAQHGQPLNMA-PQPGLGQVGISPLKP 2043
            P P+ +++    P+       G  +  A P      +  +P++P
Sbjct: 1590 PLPRPMEN-RTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQP 1632



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 75/337 (22%), Positives = 110/337 (32%), Gaps = 92/337 (27%)

Query: 86  RSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNM---GMGTS- 141
           ++ S+P++    GG   +  S   + S    L  S+   PM   G  SP +   G+ +S 
Sbjct: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQ 670

Query: 142 GPNQGPTQS-------------TGMMNSPVNQPAMGMNT--------GMNAGMNPGMLAA 180
           G    P QS              G   SPV  PA    +         +     P    +
Sbjct: 671 GEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730

Query: 181 GNGQGIMPNQVMNGSIGAGRG-----RQNMQYPNPGMGSA---------------GNLLT 220
           G    IM   +   SI   RG      Q  QY +P  GSA               G+   
Sbjct: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQ 790

Query: 221 EPLQQGSPQMGGQTGLRGPQPLK-------------MGMMNNPNPYGS-----------P 256
             +    PQ GGQ G +G  P +              GM    NP G+           P
Sbjct: 791 NSMGSYGPQ-GGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849

Query: 257 YTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA--------- 307
           Y   P  ++  + +G +     +   N+ P        P GGM    Q+ A         
Sbjct: 850 YGTLPPGRMSHASMGNRPYGPNMA--NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANS 907

Query: 308 --------PQVQQPGLV---TPVAQGMGSGAHTADPE 333
                   P + Q G++    P  QG+ S A   +P+
Sbjct: 908 IQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQ 944



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 71/321 (22%), Positives = 101/321 (31%), Gaps = 30/321 (9%)

Query: 11   PSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGDINQLQTS--L 68
            P ++ P L  P +S S S G       D  +D  D           N G    + TS  +
Sbjct: 1169 PHSQIPPL--PGMSRSNSVGIQ-----DAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221

Query: 69   GMVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQ 128
            G +    +K    S     GS P ++ G G  G +    ++ + PGLG +    +     
Sbjct: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPY 1281

Query: 129  AG-----LTSP------NMGMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGM 177
             G      T P      NM  G   PN  P+     M SP   P            + G 
Sbjct: 1282 GGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGN 1341

Query: 178  LAAGNGQGIMPNQVMNGSIGAGRGRQNMQ------YPNPGMGSAGNLLTEPLQ--QGSPQ 229
              +  G           +    + +QN +      Y  P     G + + P    QG PQ
Sbjct: 1342 QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQ 1401

Query: 230  MGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAM 289
               Q     PQP        P+P    Y Q  G    A+      +       N  PF  
Sbjct: 1402 Q-QQLPPAQPQPASQQQAAQPSPQQDVYNQY-GNAYPATATAATERRPAGGPQNQFPFQF 1459

Query: 290  DKKAVPGGGMPNMGQQPAPQV 310
             +  V      N  Q   PQ+
Sbjct: 1460 GRDRVSAPPGTNAQQNMPPQM 1480


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 138/541 (25%), Positives = 177/541 (32%), Gaps = 72/541 (13%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
            Q G   P P   T P  QQ   P  PQ        P  S  P        G         
Sbjct: 386  QMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445

Query: 1904 QVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMA 1963
              T   PP   Q P             Q  +     +Q  H Q  Q P   Q P  TP A
Sbjct: 446  SYTQQIPPYGQQGP---------SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA 496

Query: 1964 PMGMNPPPMTRGPSGHLEPGMGPTGMQ-QQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG 2022
                   P ++ P   L+    P   Q  QPP  Q   P P Q  +    P   S   + 
Sbjct: 497  QPSYQQQPQSQPP--QLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP--QSQPPYS 552

Query: 2023 QPLNMAP-------QPGLGQVGISPLKPGTVSQQALQNLLRTLR-SPSSPLQQQQVLSIL 2074
            QP   +P       QP    +      P   SQQ+ Q      R  P   L Q    S  
Sbjct: 553  QPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612

Query: 2075 HANPQLLAAFIKQRAAKYA-NSNPQPIPGQPG----MPQG-----QPGLQPPTMPGQQGV 2124
             + P + ++   Q     +  S P  +P   G    +P G      PG+    +   QG 
Sbjct: 613  SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGE 672

Query: 2125 HSNPAMQNMNPMQA----GVQ-RAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179
             SNPA    +P  +    G++  +  P   P    Q   G +SP A   N      PS  
Sbjct: 673  QSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQ 732

Query: 2180 RDILRRQQMMQQQQQQGAG-PGIGPGMANHNQFQQPQ-GVGYPPQQQQRMQHH--MQQMQ 2235
             D +    M Q    Q  G     P M    Q+  PQ G    P+Q    Q H  M   Q
Sbjct: 733  SDSIMHPSMNQSSIAQDRGYMQRNPQMP---QYSSPQPGSALSPRQPSGGQIHTGMGSYQ 789

Query: 2236 QGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPN-QAQSPHL 2294
            Q +MG  G  PQ  G + G             Q G P QPN      + LPN    S  +
Sbjct: 790  QNSMGSYG--PQ--GGQYG------------PQGGYPRQPN-----YNALPNANYPSAGM 828

Query: 2295 QGQQIPNSLSNQVRSPQPVP--SPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSS---PHP 2349
             G   P     Q+     +P     P  +  H+S   R    P+  ++ PQ  S   P P
Sbjct: 829  AGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPY-GPNMANMPPQVGSGMCPPP 887

Query: 2350 G 2350
            G
Sbjct: 888  G 888



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 103/416 (24%), Positives = 137/416 (32%), Gaps = 96/416 (23%)

Query: 680  PGMTSNGPLPDPSMIRGSVPNQMMPRITPQ--SGLNQFGQMSMAQPPIVPRQTPPLQHHG 737
            PG +  G  P     + S P   M ++ PQ   G N + Q     PP     + P Q HG
Sbjct: 364  PGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQ--GPP-----SGPQQGHG 416

Query: 738  QLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMS 797
               QP     P  Y   MQ                                    +AQ +
Sbjct: 417  YPGQPYGSQTPQRYPMTMQ-----------------------------------GRAQSA 441

Query: 798  SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPAT 857
                     I P G QG   +  Q   P  +Q SP P                 QQPP +
Sbjct: 442  MGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHP---------------QQQQPPYS 486

Query: 858  TIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQ 917
              P P  TP A P   Q     PP  Q+  PP +Q     QPS P  P    P   P SQ
Sbjct: 487  QQP-PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQ-----QPSQP--PHQQSPAPYP-SQ 537

Query: 918  QSTAASVPTPTAPLLPPQPATPL-----SQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQ- 971
            QST    P    P   PQ  +P       QPA S   Q +  P   S +    A ++++ 
Sbjct: 538  QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597

Query: 972  -PSQEVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQP 1030
             P QE+  ++        P+ T     S+   ED  +          +L   I   +D P
Sbjct: 598  PPPQELSQDSFGSQASSAPSMTS----SKGGQEDMNLSLQSRPSSLPDLSGSI---DDLP 650

Query: 1031 STSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1086
                T+ + +PG S   I   +              + +P   PF     P L GI
Sbjct: 651  --MGTEGALSPGVSTSGISSSQG------------EQSNPAQSPFSPHTSPHLPGI 692



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 137/566 (24%), Positives = 175/566 (30%), Gaps = 87/566 (15%)

Query: 1875 PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQR 1934
            P+P   N++    P     G  S G  A       PP +A   LP   P A        R
Sbjct: 109  PRPALNNNLTE--PPGGGGGGSSDGVGA-------PPHSAAAALP---PPAYGFGQPYGR 156

Query: 1935 AAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP- 1993
            +       A     Q+    Q P +  +            G  G LEP  GP        
Sbjct: 157  SPSAVAAAAAAVFHQQHGGQQSPGLAALQS----------GGGGGLEPYAGPQQNSHDHG 206

Query: 1994 -PWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQ 2052
             P  Q     P +     P PA    +  G        PG G    +  KP   S  +  
Sbjct: 207  FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGT------PGSGAAAAAGSKPPPSSSASAS 260

Query: 2053 NLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPG 2112
                   S SS   QQ+  ++    P        Q  A    +     P      QG PG
Sbjct: 261  -------SSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPG 313

Query: 2113 LQPPTMPGQQGVHSNPA---MQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN 2169
                  P   G    PA    Q      A    A       Q+    PM   S       
Sbjct: 314  GDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP 373

Query: 2170 MNHNTMPSQFRDILRRQQMMQ----QQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQ 2225
            +     PS   D + + +           Q  GP  GP    H    QP G   P +   
Sbjct: 374  LARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGP-QQGHGYPGQPYGSQTPQRYPM 432

Query: 2226 RMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHML 2285
             MQ   Q    G +    Q+P           Q  Q     QQ   P Q  P   QQ   
Sbjct: 433  TMQGRAQSAM-GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQP-- 489

Query: 2286 PNQAQSPHLQG--QQIPNSLSNQVRSPQPVPSPRPQSQPPHS-SPSP--------RMQPQ 2334
               +Q+PH Q   QQ P S   Q++S QP  S +P SQPPH  SP+P        +  PQ
Sbjct: 490  --PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQHPQ 546

Query: 2335 PSPHHVSPQTSSPH---------------------PGLVAAQANPMEQGHFASP---DQN 2370
              P +  PQ  SP+                     P    +Q     Q  F  P    Q+
Sbjct: 547  SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606

Query: 2371 SMLSQLASNPGMANLHGASATDLGLS 2396
            S  SQ +S P M +  G    D+ LS
Sbjct: 607  SFGSQASSAPSMTSSKGGQ-EDMNLS 631



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 132/552 (23%), Positives = 172/552 (31%), Gaps = 74/552 (13%)

Query: 1869 PQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG-PPPAAVE 1927
            PQ  S     P +    Y P   A  P +   A       TP   A       PPP++  
Sbjct: 198  PQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSA 257

Query: 1928 MAMQIQRAAETQR--QMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMG 1985
             A     +   QR   M              P  TP     +  P   RG  G+  PG  
Sbjct: 258  SASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGY--PGGD 315

Query: 1986 PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGT 2045
             +G  Q     +G      Q        A  + A  G                +P+ PG+
Sbjct: 316  YSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH---------APMSPGS 366

Query: 2046 VSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPG 2105
             S    Q L RT + PSSP+ Q   +      PQ           +   S PQ   G PG
Sbjct: 367  -SGGGGQPLARTPQ-PSSPMDQMGKM-----RPQPYGGTNPYSQQQGPPSGPQQGHGYPG 419

Query: 2106 MPQGQ--PGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP----QQQLQPPMG 2159
             P G   P   P TM G+       A   M  +    Q     QQ P    QQ   P   
Sbjct: 420  QPYGSQTPQRYPMTMQGR-------AQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472

Query: 2160 GMSPQAQQMNMNHNTMPSQ----FRDILRRQQMMQQQQQQGAGPGIG--PGMANHNQFQQ 2213
              SP  QQ    ++  P       +   ++Q   Q  Q Q + P     P    H Q   
Sbjct: 473  QQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPA 532

Query: 2214 PQGVGYPPQQQQRMQHHMQQ----MQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQM 2269
            P    YP QQ    QH   Q      Q       Q PQ       +   AY Q   QQ  
Sbjct: 533  P----YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQ 588

Query: 2270 GSPVQ----PNPMSPQQHMLPNQAQSP-------------HLQGQQIPNSLSNQVRSPQP 2312
             +       P P    Q    +QA S              +L  Q  P+SL +   S   
Sbjct: 589  QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDD 648

Query: 2313 VP-------SPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFA 2365
            +P       SP   +    SS   +  P  SP   SP TS   PG+     +P+      
Sbjct: 649  LPMGTEGALSPGVSTSGISSSQGEQSNPAQSPF--SPHTSPHLPGIRGPSPSPVGSPASV 706

Query: 2366 SPDQNSMLSQLA 2377
            +  ++  LS  A
Sbjct: 707  AQSRSGPLSPAA 718



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 75/300 (25%), Positives = 107/300 (35%), Gaps = 34/300 (11%)

Query: 666 PVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQ--------SGLNQFGQ 717
           P S  P       QP          P +     P    P   P         S  +   Q
Sbjct: 484 PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 718 MSMAQPPIVP--RQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFP---- 771
              +QPP      Q+P  Q   Q   P  L+    Y P+ Q   +Q     Q +FP    
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY-PQPQSQQSQQTAYSQQRFPPPQE 602

Query: 772 -SQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
            SQ    +    APS   +   Q  M+ S    + P   P   GS    P   + AL   
Sbjct: 603 LSQDSFGSQASSAPSMTSSKGGQEDMNLSL--QSRPSSLPDLSGSIDDLPMGTEGALSPG 660

Query: 831 -SPSPV---------PSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPP---GPQSQA 877
            S S +         P+++P   HT P +   + P+   P+PV +P ++     GP S A
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS---PSPVGSPASVAQSRSGPLSPA 717

Query: 878 LHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPA 937
             P  +  P PP+ Q    + PS+  +  A       R+ Q    S P P + L P QP+
Sbjct: 718 AVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPS 777



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 103/435 (23%), Positives = 142/435 (32%), Gaps = 65/435 (14%)

Query: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYL---PRTQAAGPVSQGK 1900
            QQ    P   +P     QQ TT Q PQ  SQP  + P +  PY    P+  A   +SQ  
Sbjct: 520  QQPSQPPHQQSPAPYPSQQSTTQQHPQ--SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577

Query: 1901 AAGQVTPPTPPQTAQPPLPGPPPAAVEM---AMQIQRAAETQRQMAHVQIFQRPIQHQMP 1957
            A  Q       QTA      PPP  +       Q   A          +     +Q + P
Sbjct: 578  AYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSR-P 636

Query: 1958 PMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ---------QPPWSQGGLPQPQQLQS 2008
               P     ++  PM  G  G L PG+  +G+           Q P+S    P    ++ 
Sbjct: 637  SSLPDLSGSIDDLPM--GTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG 694

Query: 2009 GMPRP--AMMSVAQ-HGQPLN--------MAPQPGLGQVGISPLKPGTVSQQALQNLLRT 2057
              P P  +  SVAQ    PL+        M P+P  GQ   S + P        Q+    
Sbjct: 695  PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSD-SIMHPSMNQSSIAQDRGYM 753

Query: 2058 LRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGM--PQGQPGLQP 2115
             R+P  P           +  Q     I      Y  ++      Q G   PQG    QP
Sbjct: 754  QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813

Query: 2116 PTMPGQQGVHSNPAMQN-MNPMQAGVQRAGLPQQQPQQQLQP------------------ 2156
                     + +  M   +NPM AG Q  G P   P   L P                  
Sbjct: 814  NYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMA 873

Query: 2157 ------------PMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPG 2204
                        P GGM+ + Q+  +  +   +  ++       M Q    G GP  G G
Sbjct: 874  NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQG 933

Query: 2205 MANHNQFQQPQGVGY 2219
            + +      PQG  Y
Sbjct: 934  INSMAGMINPQGPPY 948



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 138/626 (22%), Positives = 208/626 (33%), Gaps = 107/626 (17%)

Query: 434  PVGLGNPSSLGVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPT---QPQVQAKN 490
            P G   PS  G GQQ            P   +  Y+        +  P+   QPQ Q   
Sbjct: 453  PYGQQGPS--GYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQ 510

Query: 491  QQNQQPGQSPQGMRPMSNMSASPMGVNGGVGVQTPSLLSDSMLHSAINSQNPMMSENASV 550
             Q+ QP  S Q  +P    S +P           PS  S +  H    SQ P     A  
Sbjct: 511  LQSSQPPYSQQPSQPPHQQSPAPY----------PSQQSTTQQHP--QSQPPYSQPQAQS 558

Query: 551  PSLGPMPTAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVA 610
            P     P    PST                        QA +P P        +     A
Sbjct: 559  PYQQQQPQQPAPSTLS---------------------QQAAYPQP------QSQQSQQTA 591

Query: 611  YARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMV---PV 667
            Y+++      E + +        A  +   +   E+   +   + + LP+ +G +   P+
Sbjct: 592  YSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPM 651

Query: 668  ----SMNPGPNMG--------QPQPGMTSNGPLPDPSM--IRGSVPNQM-MPRITPQSGL 712
                +++PG +          Q  P  +   P   P +  IRG  P+ +  P    QS  
Sbjct: 652  GTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS-- 709

Query: 713  NQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPS--NQGQFLPQTQF 770
             + G +S A  P    Q PP    GQ      ++P M      Q      +   +PQ   
Sbjct: 710  -RSGPLSPAAVP--GNQMPPRPPSGQ--SDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSS 764

Query: 771  PSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
            P  G  ++  P  PS GQ          +S     P    G  G     P+  QP  +  
Sbjct: 765  PQPGSALS--PRQPSGGQIHTGMGSYQQNSMGSYGP--QGGQYGPQGGYPR--QPNYNAL 818

Query: 831  SPSPVPSRTPTPHHTPPSIGAQQ------PPATTIPAPVPTPPAM---PPGPQSQALHPP 881
              +  PS        P   G Q       PP  T+P    +  +M   P GP    + P 
Sbjct: 819  PNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ 878

Query: 882  PRQTPTPPTTQLPQQVQPSLPAA-PSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPL 940
                  PP   + ++ Q +  A   +A+  Q +P    +        T P        P 
Sbjct: 879  VGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGP--------PY 930

Query: 941  SQPAVSIEGQVS--NPP-STSSTEVNSQAIAEKQPSQ----EVKMEAKMEVDQPEPADTQ 993
             Q   S+ G ++   PP S   T  N+ A     P      +VK+    +++    AD  
Sbjct: 931  GQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMN--NKADGT 988

Query: 994  PEDISESKVEDCKMESTETEERSTEL 1019
            P+  S+SK       ST T E+ T+L
Sbjct: 989  PKTESKSKKSS---SSTTTNEKITKL 1011



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 119/508 (23%), Positives = 170/508 (33%), Gaps = 94/508 (18%)

Query: 137 GMGTSGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAGMNPGMLAAGNGQGIMPNQVMNGSI 196
           G GT  P   PT +  ++ SP +        G +    P    AG G   M +Q    + 
Sbjct: 283 GGGTPQPTATPTLNQ-LLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341

Query: 197 GAGRGRQNMQYPNPGMGSAGNLLTEPLQQGSPQMGGQTGLRGPQPL----KMGMMNNPNP 252
            A              G+       P+  GS   GGQ   R PQP     +MG M  P P
Sbjct: 342 AAAAAAA------ASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM-RPQP 394

Query: 253 YG--SPYTQNPGQQIG-ASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGG-------MPNM 302
           YG  +PY+Q  G   G   G G   Q     +    P  M  +A    G       +P  
Sbjct: 395 YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPY 454

Query: 303 GQQ------------------PAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVL 344
           GQQ                  P PQ QQP    P +Q   S    A P  ++  Q Q   
Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQP----PYSQQPPSQTPHAQPSYQQQPQSQPPQ 510

Query: 345 LLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNH------------MTHCQSGKSCQVAH 392
           L  +     ++ +    +Q   P+         H             +  Q  +  Q A 
Sbjct: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAP 570

Query: 393 CASSRQII-----SHWKNCT-----RHDCPVCLPLKNAGDKRNQQPILTGAPVGLGNPS- 441
              S+Q       S     T     R   P  L   + G + +  P +T +  G  + + 
Sbjct: 571 STLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630

Query: 442 SLGVGQQSAPNLS---------TVSQIDP----SSIERAYAALGLPYQVNQMP-TQPQVQ 487
           SL     S P+LS         T   + P    S I  +      P Q    P T P + 
Sbjct: 631 SLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLP 690

Query: 488 AKNQQNQQPGQSPQGMRPMSNMSASPMGVNGG-VGVQTPSLLSDSMLHSAIN-------- 538
                +  P  SP  +    +   SP  V G  +  + PS  SDS++H ++N        
Sbjct: 691 GIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDR 750

Query: 539 ---SQNPMMSENASVPSLGPMPTAAQPS 563
               +NP M + +S P  G   +  QPS
Sbjct: 751 GYMQRNPQMPQYSS-PQPGSALSPRQPS 777



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 92/385 (23%), Positives = 130/385 (33%), Gaps = 74/385 (19%)

Query: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTP---PQTAQPPLPGPPPAAV 1926
            QP  QP P+P  S     P+T  +   S  +  G + PPTP   P +  PPLPG    + 
Sbjct: 1127 QPKIQP-PSPAGSGSMQGPQTPQSTSSSMAEG-GDLKPPTPASTPHSQIPPLPG---MSR 1181

Query: 1927 EMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGP 1986
              ++ IQ A            FQ+  ++ M P     P  MN   M    S   EP   P
Sbjct: 1182 SNSVGIQDAFNDGSD----STFQK--RNSMTPNPGYQP-SMNTSDMMGRMS--YEPNKDP 1232

Query: 1987 TGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTV 2046
             G  ++ P S   +   Q    GM           G P + A  PGLG V + P      
Sbjct: 1233 YGSMRKAPGSDPFMSSGQGPNGGM-----------GDPYSRAAGPGLGNVAMGP------ 1275

Query: 2047 SQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQP--IPGQP 2104
                     R       P  +      +   P +            +   PQP  +P  P
Sbjct: 1276 ---------RQHYPYGGPYDR------VRTEPGI------GPEGNMSTGAPQPNLMPSNP 1314

Query: 2105 GMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQP---QQQLQPPMGGM 2161
                  P   PP    QQ    + +  N    Q     +  P QQ    QQQ Q      
Sbjct: 1315 DSGMYSPSRYPPQQQ-QQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQV----S 1369

Query: 2162 SPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP---QGVG 2218
            SP      M + T PS      +   +    + Q AGP +          Q P   + + 
Sbjct: 1370 SPAPLPRPMENRTSPS------KSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDIT 1423

Query: 2219 YPPQQQQRMQHHMQQMQQGNMGQIG 2243
            +PP   +  Q  ++Q ++  M  IG
Sbjct: 1424 FPPGSVEATQPVLKQRRRLTMKDIG 1448



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 74/368 (20%), Positives = 112/368 (30%), Gaps = 68/368 (18%)

Query: 2108 QGQPGLQPPTMPGQQGVHS--NPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQ- 2164
            + QP +QPP+  G   +     P   + +  + G  +   P   P  Q+ PP+ GMS   
Sbjct: 1125 KSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQI-PPLPGMSRSN 1183

Query: 2165 --------------------------AQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAG 2198
                                        Q +MN + M  +      +      ++  G+ 
Sbjct: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSD 1243

Query: 2199 PGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQ 2258
            P +  G   +     P      P          Q    G      +    +G E   S  
Sbjct: 1244 PFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTG 1303

Query: 2259 AYQQRLLQQQMGSPV-QPNPMSPQQHMLPNQAQ---------------SPHLQGQQIPNS 2302
            A Q  L+     S +  P+   PQQ     Q                 SP    Q     
Sbjct: 1304 APQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQ 1363

Query: 2303 LSNQVRSPQPVPSPRPQSQPPHSSP----SPRMQPQPSP---HHVSPQTSSPH------- 2348
               QV SP P+P P      P  SP      +MQ    P    H++P    P        
Sbjct: 1364 QQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDIT 1423

Query: 2349 --PGLVAAQANPMEQGH------FASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNS 2400
              PG V A    ++Q          +P+   ++  L S     +       ++ L  DNS
Sbjct: 1424 FPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNS 1483

Query: 2401 DLNSNLSQ 2408
             +  NLSQ
Sbjct: 1484 IMTFNLSQ 1491



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 71/314 (22%), Positives = 103/314 (32%), Gaps = 43/314 (13%)

Query: 670  NPGPNMGQPQPGMTSNGPLPDPSMI-RGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPR 728
            +P P++        S   +  PS    GS+     P+ T  S + + G +    P   P 
Sbjct: 1112 DPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAEGGDLKPPTPASTPH 1170

Query: 729  -QTPPLQHHGQLAQPG-----------------ALNPPMGYGPRMQQPSNQGQFLPQTQF 770
             Q PPL    +    G                 ++ P  GY P M      G+   +   
Sbjct: 1171 SQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNK 1230

Query: 771  PSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN 830
               G          S  +AP S   MSS   P N  +  P S+ +    P L   A+   
Sbjct: 1231 DPYG----------SMRKAPGSDPFMSSGQGP-NGGMGDPYSRAAG---PGLGNVAMGPR 1276

Query: 831  SPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPT 890
               P          T P IG +   +T  P P   P     G  S + +PP +Q      
Sbjct: 1277 QHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQR 1335

Query: 891  -----TQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAV 945
                  Q   Q  PS    PS      Q + Q S+ A +P P      P  +  L     
Sbjct: 1336 HDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHS--- 1392

Query: 946  SIEGQVSNPPSTSS 959
             ++ Q + PP  +S
Sbjct: 1393 GMKMQKAGPPVPAS 1406



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 75/337 (22%), Positives = 110/337 (32%), Gaps = 92/337 (27%)

Query: 86  RSGSSPNLNMGVGGPGQVMASQAQQSSPGLGLINSMVKSPMTQAGLTSPNM---GMGTS- 141
           ++ S+P++    GG   +  S   + S    L  S+   PM   G  SP +   G+ +S 
Sbjct: 611 QASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQ 670

Query: 142 GPNQGPTQS-------------TGMMNSPVNQPAMGMNT--------GMNAGMNPGMLAA 180
           G    P QS              G   SPV  PA    +         +     P    +
Sbjct: 671 GEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPS 730

Query: 181 GNGQGIMPNQVMNGSIGAGRG-----RQNMQYPNPGMGSA---------------GNLLT 220
           G    IM   +   SI   RG      Q  QY +P  GSA               G+   
Sbjct: 731 GQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQ 790

Query: 221 EPLQQGSPQMGGQTGLRGPQPLK-------------MGMMNNPNPYGS-----------P 256
             +    PQ GGQ G +G  P +              GM    NP G+           P
Sbjct: 791 NSMGSYGPQ-GGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPP 849

Query: 257 YTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA--------- 307
           Y   P  ++  + +G +     +   N+ P        P GGM    Q+ A         
Sbjct: 850 YGTLPPGRMSHASMGNRPYGPNMA--NMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANS 907

Query: 308 --------PQVQQPGLV---TPVAQGMGSGAHTADPE 333
                   P + Q G++    P  QG+ S A   +P+
Sbjct: 908 IQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQ 944



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 88/384 (22%), Positives = 126/384 (32%), Gaps = 62/384 (16%)

Query: 686  GPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGAL 745
            G  P P +   +   +  P+I P S     G  SM Q P  P+ T        +A+ G L
Sbjct: 1110 GEDPPPDIFAAADSKKSQPKIQPPSPA---GSGSM-QGPQTPQSTS-----SSMAEGGDL 1160

Query: 746  NPPMGYG-PRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVN 804
             PP     P  Q P            P  GM+ +N     S G          S+    N
Sbjct: 1161 KPPTPASTPHSQIP------------PLPGMSRSN-----SVGIQDAFNDGSDSTFQKRN 1203

Query: 805  SPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVP 864
            S    PG Q S      + + +   N   P  S    P   P     Q P         P
Sbjct: 1204 SMTPNPGYQPSMNTSDMMGRMSYEPNK-DPYGSMRKAPGSDPFMSSGQGPNGGMGD---P 1259

Query: 865  TPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQ--VQPSLPAAPSADQPQQQPRSQQSTAA 922
               A  PG  + A+ P        P  ++  +  + P    +  A QP   P +  S   
Sbjct: 1260 YSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMY 1319

Query: 923  SVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKM 982
            S         PPQ      Q   S   Q S   + S +   SQ     Q  Q+V   A +
Sbjct: 1320 SPSR-----YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPL 1374

Query: 983  EVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPG 1042
                P P                 ME+  +  +S  L + +K ++  P   A+  +PAP 
Sbjct: 1375 ----PRP-----------------MENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413

Query: 1043 QS---KKKIFKPEELRQALMPTLE 1063
            Q    ++ I  P    +A  P L+
Sbjct: 1414 QPPMIRRDITFPPGSVEATQPVLK 1437


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119,751,848
Number of Sequences: 37866
Number of extensions: 7699630
Number of successful extensions: 112248
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 743
Number of HSP's successfully gapped in prelim test: 2548
Number of HSP's that attempted gapping in prelim test: 36932
Number of HSP's gapped (non-prelim): 40364
length of query: 2414
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2295
effective length of database: 13,741,464
effective search space: 31536659880
effective search space used: 31536659880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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