BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|50345881 cytoplasmic polyadenylation element binding protein 3 [Homo sapiens] (698 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|50345881 cytoplasmic polyadenylation element binding protein ... 1455 0.0 gi|189027090 cytoplasmic polyadenylation element binding protein... 738 0.0 gi|33188441 cytoplasmic polyadenylation element binding protein ... 726 0.0 gi|33188439 cytoplasmic polyadenylation element binding protein ... 711 0.0 gi|119395725 cytoplasmic polyadenylation element binding protein... 214 2e-55 gi|119395722 cytoplasmic polyadenylation element binding protein... 214 2e-55 gi|119395720 cytoplasmic polyadenylation element binding protein... 214 2e-55 gi|119395718 cytoplasmic polyadenylation element binding protein... 208 1e-53 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 68 3e-11 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 64 4e-10 gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 64 4e-10 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 64 6e-10 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 60 5e-09 gi|150417989 cyclin K isoform 1 [Homo sapiens] 60 5e-09 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 60 9e-09 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 59 1e-08 gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 1e-08 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 59 2e-08 gi|110832843 TBP-associated factor 4 [Homo sapiens] 58 3e-08 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 57 4e-08 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 57 4e-08 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 57 4e-08 gi|146134388 YLP motif containing 1 [Homo sapiens] 57 4e-08 gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 57 8e-08 gi|55750053 atrophin-1 [Homo sapiens] 56 1e-07 gi|55750041 atrophin-1 [Homo sapiens] 56 1e-07 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 56 1e-07 gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 56 1e-07 gi|61966923 forkhead box B2 [Homo sapiens] 56 1e-07 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07 >gi|50345881 cytoplasmic polyadenylation element binding protein 3 [Homo sapiens] Length = 698 Score = 1455 bits (3767), Expect = 0.0 Identities = 698/698 (100%), Positives = 698/698 (100%) Query: 1 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA Sbjct: 1 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60 Query: 61 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE Sbjct: 61 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120 Query: 121 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 180 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ Sbjct: 121 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 180 Query: 181 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS Sbjct: 181 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240 Query: 241 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 300 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV Sbjct: 241 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 300 Query: 301 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 360 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD Sbjct: 301 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 360 Query: 361 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL 420 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL Sbjct: 361 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL 420 Query: 421 SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY 480 SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY Sbjct: 421 SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY 480 Query: 481 FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD 540 FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD Sbjct: 481 FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD 540 Query: 541 GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN 600 GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN Sbjct: 541 GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN 600 Query: 601 QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ 660 QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ Sbjct: 601 QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ 660 Query: 661 YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698 YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS Sbjct: 661 YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698 >gi|189027090 cytoplasmic polyadenylation element binding protein 4 [Homo sapiens] Length = 729 Score = 738 bits (1906), Expect = 0.0 Identities = 418/726 (57%), Positives = 489/726 (67%), Gaps = 94/726 (12%) Query: 1 MQDDLL-MDKSKTQPQPQQQ--QRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALS 57 +QD++L +K+K+Q Q QQ ++QQ P P P T E K EEN + Sbjct: 70 IQDEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPET----EKAKSEENQGDNSSE 125 Query: 58 PAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWS----- 112 NG +K+++ESP+L G + + Q P AS F S WS Sbjct: 126 NG------NGKEKIRIESPVLTGFDYQEATGLGTSTQ-PLTSSASSLTGF-SNWSAAIAP 177 Query: 113 TGTTNAVEDS--FFQGITPV----NGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166 + +T ED+ F QG P NG +LFQNFPHHV+P FGG+FSPQIG +QHH Sbjct: 178 SSSTIINEDASFFHQGGVPAASANNGALLFQNFPHHVSPGFGGSFSPQIG-PLSQHHPHH 236 Query: 167 PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAV 226 P Q +Q QQRRSPASP P+ R+AA + P + + Sbjct: 237 PH----------FQHHHSQHQQQRRSPASPHPPPFTHRNAA--FNQLPHLANN------- 277 Query: 227 AAAAAAAAASSASSSWNTHQSVNAAWSAPSNP-------WGGLQAGRDPRRAVGVGVGVG 279 + S W+++QS + S+ +P WGG Q GRD RR + G+ Sbjct: 278 --------LNKPPSPWSSYQSPSPTPSSSWSPGGGGYGGWGGSQ-GRDHRRGLNGGI--- 325 Query: 280 VGVPSPLNPISPLKKPFSSNVIAPPKFPR-AAPLTSKSWMEDNAFRTDNGNNLLPFQDRS 338 +PLN ISPLKK F+SN I K+ R ++ KSWMED+ R DN + PF DR Sbjct: 326 ----TPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSWMEDSLNRADN---IFPFPDRP 378 Query: 339 RPYDTFNLHSLENSLMDMIRTDHEPLKGK---HYPPSGPPMSFADIMWRNHFAGRMGINF 395 R TF++HSLE+SL+D++R +++ +KG+ YP S + ++ GR Sbjct: 379 R---TFDMHSLESSLIDIMRAENDTIKGRLNYSYPGSD-----SSLLINARTYGR----- 425 Query: 396 HHPGTDNIMALNNAFLDDSHGDQALSSGLSSPTRC---QNGERVERYSRKVFVGGLPPDI 452 G ++ + + FLDD GDQ L SGL SP C QNGERVERYSRKVFVGGLPPDI Sbjct: 426 -RRGQSSLFPMEDGFLDDGRGDQPLHSGLGSP-HCFSHQNGERVERYSRKVFVGGLPPDI 483 Query: 453 DEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLY 512 DEDEITASFRRFGPL+VDWPHKAESKSYFPPKGYAFLLFQ+ESSVQALIDAC+EEDGKLY Sbjct: 484 DEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLY 543 Query: 513 LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL 572 LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL Sbjct: 544 LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL 603 Query: 573 YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLD 632 YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQH +IDKRVEVKPYVLD Sbjct: 604 YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLD 663 Query: 633 DQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRH 692 DQ+CDECQG RCGGKFAPFFCANVTCLQYYCEYCWA+IHSRAGREFHKPLVKEGGDRPRH Sbjct: 664 DQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRH 723 Query: 693 VPFRWS 698 + FRW+ Sbjct: 724 ISFRWN 729 >gi|33188441 cytoplasmic polyadenylation element binding protein 2 isoform A [Homo sapiens] Length = 559 Score = 726 bits (1875), Expect = 0.0 Identities = 391/630 (62%), Positives = 435/630 (69%), Gaps = 110/630 (17%) Query: 104 SPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPV-----------FGGTFS 152 SP + + G +++ +FF +PV+ PH + FGG FS Sbjct: 5 SPDSENGFYPGLPSSMNPAFFPSFSPVS--------PHGCTGLSVPTSGGGGGGFGGPFS 56 Query: 153 PQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP--PQQRRSPASPSQAPYAQRSAAA-- 208 PPPP PA Q PP A P PQ RRSP SP Q +AAA Sbjct: 57 ATA---------VPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFL 107 Query: 209 ----AYGH-QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263 +Y H QP++ P W+ HQS + W S WG + Sbjct: 108 QQRNSYNHHQPLLKQSP---------------------WSNHQS--SGWGTGSMSWGAMH 144 Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNA 322 GRD RR +G+ P +N ISPLKKPFS NVIAPPKF R+ P LT KSW+EDN Sbjct: 145 -GRDHRRTGNMGI------PGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNV 197 Query: 323 FRTDNGNN-LLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPLKGKHYPPSGPPMSFADI 381 FRTDN +N LLP QDRSR YD+ N+HSLENSL+D++R +H+PLKG+ Sbjct: 198 FRTDNNSNTLLPLQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGR-------------- 243 Query: 382 MWRNHFAGRMGINFHHPGTDNIMALN---------NAFLDDSHGDQALSSGLSSPTRC-- 430 +++ HPGTDN++ LN + LDD H DQ L+SPT C Sbjct: 244 -----------LSYPHPGTDNLLMLNGRSSLFPIDDGLLDDGHSDQV--GVLNSPT-CYS 289 Query: 431 --QNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF 488 QNGER+ER+SRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF Sbjct: 290 AHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF 349 Query: 489 LLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR 548 LLFQEESSVQALIDAC+EEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR Sbjct: 350 LLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR 409 Query: 549 KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI 608 KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI Sbjct: 410 KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI 469 Query: 609 SARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWA 668 SARFVQLQH DIDKRVEVKPYVLDDQMCDECQG RCGGKFAPFFCANVTCLQYYCE+CWA Sbjct: 470 SARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWA 529 Query: 669 SIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698 +IHSRAGREFHKPLVKEG DRPR + FRW+ Sbjct: 530 NIHSRAGREFHKPLVKEGADRPRQIHFRWN 559 Score = 32.7 bits (73), Expect = 1.2 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 27/97 (27%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMES---------- 75 P P+S P P S PA P+ +P +P+G + + + Sbjct: 4 PSPDSENGFYPGLPSSMN----------PAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGG 53 Query: 76 -------PLLPGLSFHQPPQQPPPPQEPAAPGASLSP 105 P P + + P QQPPPP P P + SP Sbjct: 54 PFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSP 90 >gi|33188439 cytoplasmic polyadenylation element binding protein 2 isoform B [Homo sapiens] Length = 589 Score = 711 bits (1834), Expect = 0.0 Identities = 391/660 (59%), Positives = 435/660 (65%), Gaps = 140/660 (21%) Query: 104 SPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPV-----------FGGTFS 152 SP + + G +++ +FF +PV+ PH + FGG FS Sbjct: 5 SPDSENGFYPGLPSSMNPAFFPSFSPVS--------PHGCTGLSVPTSGGGGGGFGGPFS 56 Query: 153 PQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP--PQQRRSPASPSQAPYAQRSAAA-- 208 PPPP PA Q PP A P PQ RRSP SP Q +AAA Sbjct: 57 ATA---------VPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFL 107 Query: 209 ----AYGH-QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263 +Y H QP++ P W+ HQS + W S WG + Sbjct: 108 QQRNSYNHHQPLLKQSP---------------------WSNHQS--SGWGTGSMSWGAMH 144 Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNA 322 GRD RR +G+ P +N ISPLKKPFS NVIAPPKF R+ P LT KSW+EDN Sbjct: 145 -GRDHRRTGNMGI------PGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNV 197 Query: 323 FRTDNGNN-LLPFQ------------------------------DRSRPYDTFNLHSLEN 351 FRTDN +N LLP Q DRSR YD+ N+HSLEN Sbjct: 198 FRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLEN 257 Query: 352 SLMDMIRTDHEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALN---- 407 SL+D++R +H+PLKG+ +++ HPGTDN++ LN Sbjct: 258 SLIDIMRAEHDPLKGR-------------------------LSYPHPGTDNLLMLNGRSS 292 Query: 408 -----NAFLDDSHGDQALSSGLSSPTRC----QNGERVERYSRKVFVGGLPPDIDEDEIT 458 + LDD H DQ L+SPT C QNGER+ER+SRKVFVGGLPPDIDEDEIT Sbjct: 293 LFPIDDGLLDDGHSDQV--GVLNSPT-CYSAHQNGERIERFSRKVFVGGLPPDIDEDEIT 349 Query: 459 ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSP 518 ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDAC+EEDGKLYLCVSSP Sbjct: 350 ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSP 409 Query: 519 TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY 578 TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY Sbjct: 410 TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY 469 Query: 579 AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDE 638 AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQH DIDKRVEVKPYVLDDQMCDE Sbjct: 470 AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDE 529 Query: 639 CQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698 CQG RCGGKFAPFFCANVTCLQYYCE+CWA+IHSRAGREFHKPLVKEG DRPR + FRW+ Sbjct: 530 CQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN 589 Score = 32.7 bits (73), Expect = 1.2 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 27/97 (27%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMES---------- 75 P P+S P P S PA P+ +P +P+G + + + Sbjct: 4 PSPDSENGFYPGLPSSMN----------PAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGG 53 Query: 76 -------PLLPGLSFHQPPQQPPPPQEPAAPGASLSP 105 P P + + P QQPPPP P P + SP Sbjct: 54 PFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSP 90 >gi|119395725 cytoplasmic polyadenylation element binding protein 1 isoform 1 [Homo sapiens] Length = 561 Score = 214 bits (546), Expect = 2e-55 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%) Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498 YS KVF+GG+P DI E + +FR FG L V+WP K PPKGY +L+F+ E SV+ Sbjct: 309 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 368 Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552 +L+ AC L DG + Y +SS ++ K VQ+ PW L+DS+FV SQ LDP +T+F Sbjct: 369 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 428 Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612 VG + L A LA I++ L+GGV YAGIDTD KYP G+GRV F+NQ+SY+ A+SA F Sbjct: 429 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 487 Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672 V+++ K+V++ PY L+D +C C + PFFC + C +Y+C CW HS Sbjct: 488 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 541 Query: 673 RAGREFHKPLVKEGGDR 689 G H PL++ +R Sbjct: 542 MEGLRHHSPLMRNQKNR 558 >gi|119395722 cytoplasmic polyadenylation element binding protein 1 isoform 3 [Homo sapiens] Length = 486 Score = 214 bits (546), Expect = 2e-55 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%) Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498 YS KVF+GG+P DI E + +FR FG L V+WP K PPKGY +L+F+ E SV+ Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 293 Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552 +L+ AC L DG + Y +SS ++ K VQ+ PW L+DS+FV SQ LDP +T+F Sbjct: 294 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 353 Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612 VG + L A LA I++ L+GGV YAGIDTD KYP G+GRV F+NQ+SY+ A+SA F Sbjct: 354 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 412 Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672 V+++ K+V++ PY L+D +C C + PFFC + C +Y+C CW HS Sbjct: 413 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 466 Query: 673 RAGREFHKPLVKEGGDR 689 G H PL++ +R Sbjct: 467 MEGLRHHSPLMRNQKNR 483 >gi|119395720 cytoplasmic polyadenylation element binding protein 1 isoform 3 [Homo sapiens] Length = 486 Score = 214 bits (546), Expect = 2e-55 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%) Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498 YS KVF+GG+P DI E + +FR FG L V+WP K PPKGY +L+F+ E SV+ Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 293 Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552 +L+ AC L DG + Y +SS ++ K VQ+ PW L+DS+FV SQ LDP +T+F Sbjct: 294 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 353 Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612 VG + L A LA I++ L+GGV YAGIDTD KYP G+GRV F+NQ+SY+ A+SA F Sbjct: 354 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 412 Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672 V+++ K+V++ PY L+D +C C + PFFC + C +Y+C CW HS Sbjct: 413 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 466 Query: 673 RAGREFHKPLVKEGGDR 689 G H PL++ +R Sbjct: 467 MEGLRHHSPLMRNQKNR 483 >gi|119395718 cytoplasmic polyadenylation element binding protein 1 isoform 2 [Homo sapiens] Length = 491 Score = 208 bits (530), Expect = 1e-53 Identities = 115/262 (43%), Positives = 159/262 (60%), Gaps = 18/262 (6%) Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKG-----YAFLLFQE 493 YS KVF+GG+P DI E + +FR FG L V+WP K PPKG Y +L+F+ Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFEL 293 Query: 494 ESSVQALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDP 547 E SV++L+ AC L DG + Y +SS ++ K VQ+ PW L+DS+FV SQ LDP Sbjct: 294 EKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDP 353 Query: 548 RKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAA 607 +T+FVG + L A LA I++ L+GGV YAGIDTD KYP G+GRV F+NQ+SY+ A Sbjct: 354 SRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKA 412 Query: 608 ISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCW 667 +SA FV+++ K+V++ PY L+D +C C + PFFC + C +Y+C CW Sbjct: 413 VSAAFVEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCW 466 Query: 668 ASIHSRAGREFHKPLVKEGGDR 689 HS G H PL++ +R Sbjct: 467 HWRHSMEGLRHHSPLMRNQKNR 488 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 68.2 bits (165), Expect = 3e-11 Identities = 96/318 (30%), Positives = 120/318 (37%), Gaps = 41/318 (12%) Query: 11 KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDK 70 +T P + P P +AP +PL+ TP PE S++ A P APPA P Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLT--TPPPETPSSI-ATPPPQAPPALASPPL 603 Query: 71 MQMESPLLPGLSFHQPPQQPP-----PPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125 + SP L L+ PPQ PP P Q P +P AS S +T S NA+ Q Sbjct: 604 QGLPSPPLSPLAT-PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662 Query: 126 GITPVNGTMLFQNFPHH-VNPVFGGTFSPQIGLAQTQHHQQPP----PPAPAPQ--PAQP 178 F P V F SP + + T Q PP PP P PA P Sbjct: 663 AP--------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714 Query: 179 AQPPQAQPPQQRRSP--ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAAS 236 P A PP Q P A P Q P S A+ P T P +AA S Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVP---PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771 Query: 237 SASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296 +S + + + P+ LQA P + G PS P+SPL P Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF---PGQAPFSPSASLPMSPLATP- 827 Query: 297 SSNVIAPPKFP--RAAPL 312 PP+ P AAPL Sbjct: 828 ------PPQAPPVLAAPL 839 Score = 56.2 bits (134), Expect = 1e-07 Identities = 73/296 (24%), Positives = 114/296 (38%), Gaps = 30/296 (10%) Query: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67 + S T+P P ++R P + S LSS SA P SPA + P+ G Sbjct: 214 EHSTTEPSPAARRR----PSAGGGLQRPASRSLSS--------SATPLSSPARSGPSARG 261 Query: 68 PDKMQME--SPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWS-TGTTNAVEDSFF 124 + P GL +PPQ PP ++ A LS S +T S +GT Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321 Query: 125 QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ--PP 182 TP+ T+ P P+ +P A P PPA P A P+ PP Sbjct: 322 NAATPLPATL--PPSPPLATPL---PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376 Query: 183 QAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSW 242 PP + P P Q P++ S + P+ S +++++ + A S + S Sbjct: 377 MQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS- 433 Query: 243 NTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNP-ISPLKKPFS 297 + A+ ++PS P P + + + + L+P +SPL P + Sbjct: 434 --PRQTQASLTSPSRP--ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485 Score = 51.2 bits (121), Expect = 3e-06 Identities = 59/246 (23%), Positives = 81/246 (32%), Gaps = 21/246 (8%) Query: 28 PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPP 87 P S + P +P ++ P+ A P L +PPA P +P L P Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766 Query: 88 QQPPPPQE--PAAPGASLSPSFGSTWSTGTTNAVED--SFFQGITPVNGTMLFQNFPHHV 143 Q PP P P +P A P +T A+ + F G P + + P Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826 Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRS----------- 192 P +P + A Q PP P +P P +PP P Sbjct: 827 PP----PQAPPVLAAPLL--QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 880 Query: 193 PASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAW 252 P PS++P + S GH TS P + AA+S AAW Sbjct: 881 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940 Query: 253 SAPSNP 258 S P Sbjct: 941 SRGPAP 946 Score = 50.1 bits (118), Expect = 7e-06 Identities = 83/333 (24%), Positives = 114/333 (34%), Gaps = 80/333 (24%) Query: 16 PQQQQRQQQQP-QPESSVSEAP--STPLSSETPKPEENSAVPALSPAAAPPAPN---GPD 69 P+Q Q P +P S+ ++P PLS P + S PA+SP ++P + Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493 Query: 70 KMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITP 129 + SP P S PP + Q AP + +P T Sbjct: 494 SLASHSPQAPLSSLIMPPLET---QSSLAPPSLQTPPASLT------------------- 531 Query: 130 VNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA---------- 179 T +N P P +P T H + PP PAP P A P+ Sbjct: 532 ---TPPLENLPSLAPPPLQTASAP----LTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584 Query: 180 -----QPPQAQP----------PQQRRSPAS--PSQAP--------YAQRSAAAAYGHQP 214 PPQA P P SP + P QAP A S A+ P Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644 Query: 215 IMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274 + T P + +A+A A S S V A +S P++P A P +A Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPS-----PPVQAPFSPPASPPVSPSA-TPPSQAPPS 698 Query: 275 GVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFP 307 + VP P P P S + PP+ P Sbjct: 699 LAAPPLQVP----PSPPASPPMSPSATPPPQAP 727 Score = 40.8 bits (94), Expect = 0.004 Identities = 65/262 (24%), Positives = 100/262 (38%), Gaps = 30/262 (11%) Query: 51 SAVPALSPAAAPPAPNGPDKMQMES-PLLPGLSFHQPPQQPPPPQEPAAPG-ASLSPSFG 108 + +P +P A P G S P G PP + P ++PG AS + G Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127 Query: 109 STWSTGTTNAVEDSFFQG--ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166 G + E++ +G + L + GT SP + + Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187 Query: 167 --PPPAPAPQPAQPAQ-PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSS 223 P PAP+ +P P + P ++ S PS P A+R +A G Q +P+S Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS--PAARRRPSAGGGLQ-----RPASR 240 Query: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPW-GGLQAGRDPRRAVGVGVGVGVGV 282 S +++A SS + S + + A + PS P GLQA R P+ V Sbjct: 241 S---LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ------------V 285 Query: 283 PSPLNPISPLKKPFSSNVIAPP 304 P +P P SS+ +A P Sbjct: 286 TPPRKDAAPALGPLSSSPLATP 307 Score = 40.0 bits (92), Expect = 0.007 Identities = 57/229 (24%), Positives = 77/229 (33%), Gaps = 41/229 (17%) Query: 28 PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPG------- 80 P S + P +PL++ P+ A P L +PPA P P PG Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSG 869 Query: 81 --LSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQN 138 L+ P PPPP +P ++LS + S+ T+ E+ + G Sbjct: 870 PRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEE--------LRG------ 913 Query: 139 FPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP-- 196 + P G SP H PAP A P P P S Sbjct: 914 --YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971 Query: 197 ------SQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239 ++ P + A A P P +S AAA A A ASS S Sbjct: 972 LCTIYETEGPESATPAPGALDPGP----SPGTSGGKAAAGAGAGASSRS 1016 Score = 32.3 bits (72), Expect = 1.5 Identities = 77/361 (21%), Positives = 116/361 (32%), Gaps = 43/361 (11%) Query: 31 SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90 S E + ++E PK SA + P P P G P P Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 91 PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150 P G S S S ST E S P G L + ++ Sbjct: 195 SARPRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 151 FSPQIGLAQTQHHQQPP--PPAPAPQPAQPAQPPQAQPPQQRRSPA--SPSQAPYAQRSA 206 SP + + P P P P+ Q +PPQ PP++ +PA S +P A S Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309 Query: 207 AAAYGH---QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263 + P + P ++ + A A S + S+ S P+ P Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP----- 364 Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF---SSNVIAPPKFPRAAPLTSKSWMED 320 P +A + P L I P++ P S ++ APP +PL S Sbjct: 365 ----PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP-----SPLALSSLQAT 415 Query: 321 NAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIR-----TDHEPLKGKHYPPSGPP 375 + + P + + T + + SL R D PL+ P+ PP Sbjct: 416 TSLGS-------PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468 Query: 376 M 376 + Sbjct: 469 L 469 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 64.3 bits (155), Expect = 4e-10 Identities = 70/309 (22%), Positives = 107/309 (34%), Gaps = 29/309 (9%) Query: 25 QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84 +P P + P P +P + +P + P P P GP +Q + P +S Sbjct: 48 RPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM 107 Query: 85 QPP---QQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF------QGITPVNGTML 135 PP PP APG P W T + ++ T +G + Sbjct: 108 PPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKV 167 Query: 136 FQNFPHHVNPVFGGTFSPQI-----------GLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184 Q + P+ Q AQ Q Q A A AQ QA Sbjct: 168 IQQ--SELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 225 Query: 185 QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244 Q Q ++ A Q A Q + S P++SS A + + ++S+ SS+ +T Sbjct: 226 QAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTST 285 Query: 245 HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGV-GVGVGVPSP-LNPISPLKKPFSSNVIA 302 + + S P + P AV V V V P+P P+ + +P + Sbjct: 286 TTTATSVAQTVSTP---TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL-- 340 Query: 303 PPKFPRAAP 311 PP P + P Sbjct: 341 PPAVPHSVP 349 Score = 51.6 bits (122), Expect = 2e-06 Identities = 60/254 (23%), Positives = 96/254 (37%), Gaps = 17/254 (6%) Query: 5 LLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPA 64 +L +++ Q Q Q Q + Q Q Q ++ ++A + + + + + A + A A Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 234 Query: 65 PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124 + Q+++ + + P PA P S S S + ST +T S Sbjct: 235 AQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA-PAVSTSTSSSTPSSTTSTTTTATSVA 293 Query: 125 QGI-TPVNGTMLFQNFPHHVNPVFG-GTFSPQIGLAQT--QHHQQPPPPA-----PAPQP 175 Q + TP + P T +P QT Q H Q PPA P P Sbjct: 294 QTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT 353 Query: 176 AQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAA 235 A PA PP PP + P P P G P + A+AA+ A A Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLP------GVLPGMAPPIVPMIHPQVAIAASPATLAG 407 Query: 236 SSASSSWNTHQSVN 249 ++A S W +++ + Sbjct: 408 ATAVSEWTEYKTAD 421 >gi|21327715 transcription elongation regulator 1 isoform 1 [Homo sapiens] Length = 1098 Score = 64.3 bits (155), Expect = 4e-10 Identities = 70/309 (22%), Positives = 107/309 (34%), Gaps = 29/309 (9%) Query: 25 QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84 +P P + P P +P + +P + P P P GP +Q + P +S Sbjct: 48 RPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM 107 Query: 85 QPP---QQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF------QGITPVNGTML 135 PP PP APG P W T + ++ T +G + Sbjct: 108 PPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKV 167 Query: 136 FQNFPHHVNPVFGGTFSPQI-----------GLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184 Q + P+ Q AQ Q Q A A AQ QA Sbjct: 168 IQQ--SELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 225 Query: 185 QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244 Q Q ++ A Q A Q + S P++SS A + + ++S+ SS+ +T Sbjct: 226 QAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTST 285 Query: 245 HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGV-GVGVGVPSP-LNPISPLKKPFSSNVIA 302 + + S P + P AV V V V P+P P+ + +P + Sbjct: 286 TTTATSVAQTVSTP---TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL-- 340 Query: 303 PPKFPRAAP 311 PP P + P Sbjct: 341 PPAVPHSVP 349 Score = 48.9 bits (115), Expect = 2e-05 Identities = 63/269 (23%), Positives = 99/269 (36%), Gaps = 26/269 (9%) Query: 5 LLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPA 64 +L +++ Q Q Q Q + Q Q Q ++ ++A + + + + + A + A A Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 234 Query: 65 PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124 + Q+++ + + P PA P S S S + ST +T S Sbjct: 235 AQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA-PAVSTSTSSSTPSSTTSTTTTATSVA 293 Query: 125 QGI-TPVNGTMLFQNFPHHVNPVFG-GTFSPQIGLAQT--QHHQQPPPPA-----PAPQP 175 Q + TP + P T +P QT Q H Q PPA P P Sbjct: 294 QTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT 353 Query: 176 AQPAQPPQAQPPQQRRSPASP-----------SQAPYAQRSAAAAYGHQPIM----TSKP 220 A PA PP PP + P P PY + A G P M Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMI 413 Query: 221 SSSSAVAAAAAAAAASSASSSWNTHQSVN 249 A+AA+ A A ++A S W +++ + Sbjct: 414 HPQVAIAASPATLAGATAVSEWTEYKTAD 442 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 63.5 bits (153), Expect = 6e-10 Identities = 71/257 (27%), Positives = 99/257 (38%), Gaps = 38/257 (14%) Query: 14 PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDK--- 70 P+P+++Q+ Q P + SE ++ P NS VP LSP + P P++ Sbjct: 523 PKPERKQQPQLPRPPTTGGSEGAG---AAPCPPNPANSWVPGLSPGGSRRPPRSPERTLS 579 Query: 71 ------MQMESPLLPGLSFHQPP-----QQPPPPQEPA---APGASLSPSFGSTWSTGTT 116 Q +P LP PP QPP P+ +PGAS+S S S S+ + Sbjct: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 Query: 117 NAVED-SFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQP 175 A D S Q +TP+ + PH P FSP ++ + P APA P Sbjct: 640 PAPSDRSGPQILTPLGDRFVIP--PH---PKVPAPFSPPPSKPRSPNPAAPALAAPAVVP 694 Query: 176 -------AQPAQPPQAQ---PPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSA 225 A P PP Q P Q S Q+P S +Y P T KP Sbjct: 695 GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSP--PPSPPPSYHPPPPPTKKPEVVVE 752 Query: 226 VAAAAAAAAASSASSSW 242 +A+ A +W Sbjct: 753 APSASETAEEPLQDPNW 769 Score = 48.1 bits (113), Expect = 3e-05 Identities = 80/360 (22%), Positives = 125/360 (34%), Gaps = 43/360 (11%) Query: 23 QQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLS 82 Q P P+++++ +P+ S+ P S P+ P PP P ++ +E+P + Sbjct: 705 QSPPTPQTTLTPLQESPVISKDQSPPP-SPPPSYHP---PPPPTKKPEVVVEAPSASETA 760 Query: 83 FHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFP 140 +P Q P PPP PA LS + E++FF +P P Sbjct: 761 -EEPLQDPNWPPPPPPAPEEQDLSMA--------DFPPPEEAFFSVASPEPAGP--SGSP 809 Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200 V+ + S Q PPP PAP PA A A+ PQ+ S P Sbjct: 810 ELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP 869 Query: 201 YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWG 260 + A + + S A A A SA ++++ S P Sbjct: 870 PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQK-PLRRALSGRASPVPAPSS 928 Query: 261 GLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKSWMED 320 GL A +A + G+ P P P A P +S Sbjct: 929 GLHAA-VRLKACSLAASEGLSSAQPNGP------------------PEAEPRPPQSPAST 969 Query: 321 NAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHE---PLKGKHYPPSGPPMS 377 +F G+ L + RP L+ +L+ +R+ E P K P + PP++ Sbjct: 970 ASFIFSKGSRKLQLE---RPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVA 1026 Score = 42.4 bits (98), Expect = 0.001 Identities = 81/329 (24%), Positives = 111/329 (33%), Gaps = 68/329 (20%) Query: 10 SKTQPQPQQQQRQQQQPQP---ESSVSEAPSTP-----LSSETPKPEENSAVPAL--SPA 59 S+T +P Q P P E +S A P S +P+P S P L SPA Sbjct: 757 SETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPA 816 Query: 60 AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPG--ASLSPSFGSTWSTGTTN 117 A+ + +Q++ P P PP P P +APG A L S G Sbjct: 817 ASSSSATA---LQIQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP 869 Query: 118 AVEDSFFQGITPVNGTML---FQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAP- 173 ED +TP M+ P G +PQ L + + P PAP+ Sbjct: 870 PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSG 929 Query: 174 ------------------QPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI 215 AQP PP+A+P P Q+P + S + G + + Sbjct: 930 LHAAVRLKACSLAASEGLSSAQPNGPPEAEP--------RPPQSPASTASFIFSKGSRKL 981 Query: 216 MTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVG 275 +P S A A S S P P + P+ V Sbjct: 982 QLERPVSPETQADLQRNLVAELRSISEQR---------PPQAP------KKSPKAPPPVA 1026 Query: 276 VGVGVGVPSPLNPISPLKKPFSSNVIAPP 304 VGVP P +P P +P + APP Sbjct: 1027 RKPSVGVPPPASPSYPRAEPLT----APP 1051 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 60.5 bits (145), Expect = 5e-09 Identities = 94/358 (26%), Positives = 118/358 (32%), Gaps = 94/358 (26%) Query: 161 QHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP---SQAPYAQRSAAAAYGHQPIMT 217 Q QQPPP P PQ P QPP P Q++ P P S P + A G + + Sbjct: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG---VGS 123 Query: 218 SKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSA------PSNPWGGL-----QAGR 266 + P+SSSA A + A S T A SA P+ P G+ QAG Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG 183 Query: 267 DPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKSWMEDNAFRTD 326 P V G G G P P + PK P P T Sbjct: 184 PPPPPAAV-PGPGPGPKQGPGPGGPK----GGKMPGGPK-PGGGP----------GLSTP 227 Query: 327 NGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPLKGKHY---PPSGPPMSFADIMW 383 G+ P + P R H P +H+ PP GP Sbjct: 228 GGHPKPPHRGGGEPRGG--------------RQHHPPYHQQHHQGPPPGGP--------- 264 Query: 384 RNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQALSSGLSSPTRCQNGERVERYSRKV 443 GR + + DS G +A S L P GE+ ++ Sbjct: 265 ----GGR----------------SEEKISDSEGFKANLSLLRRP-----GEKTYTQRCRL 299 Query: 444 FVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALI 501 FVG LP DI EDE F ++G E F KG F + ES A I Sbjct: 300 FVGNLPADITEDEFKRLFAKYG----------EPGEVFINKGKGFGFIKLESRALAEI 347 Score = 57.8 bits (138), Expect = 3e-08 Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 20/177 (11%) Query: 14 PQPQQQQRQQQQPQPESS----VSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69 P PQ Q+QQ P P+ S V++ P + P +SA PA P + P +GP Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148 Query: 70 KMQMESPLLPGLSFHQPPQQPP-------PPQ---EPAAPGASLSPSFGSTWSTGTTNAV 119 P + PP PP PPQ P P A P G G Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208 Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLA-----QTQHHQQPPPPAP 171 G P G L H P GG P+ G QHHQ PPP P Sbjct: 209 GGKMPGGPKPGGGPGLSTPGGHPKPPHRGGG-EPRGGRQHHPPYHQQHHQGPPPGGP 264 Score = 49.7 bits (117), Expect = 9e-06 Identities = 47/193 (24%), Positives = 60/193 (31%), Gaps = 20/193 (10%) Query: 14 PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM 73 P P Q + P P P+ P ++ P P PP P Q Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93 Query: 74 ESPLLPGLSFHQPPQQPPPPQEPAAP----GASLSPSFGSTWSTGTTNAVEDSFFQGITP 129 HQ Q PPPPQ+ + P G +P GS ++ G P Sbjct: 94 ----------HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143 Query: 130 VNGTMLFQNFPHHVNPVFGGT---FSPQIGLAQTQHHQQPPPPAPAPQPAQ---PAQPPQ 183 +G P V G P G+ T PPP PA P P Q P Sbjct: 144 GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203 Query: 184 AQPPQQRRSPASP 196 P+ + P P Sbjct: 204 PGGPKGGKMPGGP 216 Score = 40.0 bits (92), Expect = 0.007 Identities = 43/157 (27%), Positives = 50/157 (31%), Gaps = 22/157 (14%) Query: 62 PPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPA--APGASLSPSFGSTWSTGTTNAV 119 PP P P Q + QPP Q PPPQ+P P P ++ Sbjct: 58 PPIPPPPPHQQQQ----------QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107 Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179 + QG P G P T G P P P P PA + Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG--------SGPGPTPTPPPAVTS 159 Query: 180 QPPQAQPPQQRRS--PASPSQAPYAQRSAAAAYGHQP 214 PP A PP S P +P QA AA G P Sbjct: 160 APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 60.5 bits (145), Expect = 5e-09 Identities = 50/190 (26%), Positives = 72/190 (37%), Gaps = 13/190 (6%) Query: 16 PQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAP---NGPDKMQ 72 P+++ + + P P+ E PL P P+ + A A PP P K+Q Sbjct: 341 PKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQ 400 Query: 73 MESPLLPGLSFHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPV 130 + P P HQPP P PPP P++ +S + S++ +G S + P Sbjct: 401 IPPPAHPA-PVHQPPPLPHRPPPPPPSSYMTGMSTT--SSYMSGEGYQSLQSMMKTEGPS 457 Query: 131 NGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQR 190 G + P P + P + PPPPA P PA P P PP Sbjct: 458 YGAL-----PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPT 512 Query: 191 RSPASPSQAP 200 +P P P Sbjct: 513 YNPNFPPPPP 522 Score = 53.5 bits (127), Expect = 6e-07 Identities = 58/232 (25%), Positives = 79/232 (34%), Gaps = 51/232 (21%) Query: 10 SKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSP-----AAAPPA 64 S++ Q QQ+ QQP + ++ P P S + P + +SP AA PP Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKP-SPQPSSPRQVKRAVVVSPKEENKAAEPPP 352 Query: 65 PNGPDKMQMESPLLPGLSFHQPPQQPPP------PQEPAAPGASLS-------------- 104 P P K++ P LP H PP + PP EP P + Sbjct: 353 PKIP-KIETTHPPLP--PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409 Query: 105 ------------PSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGG--- 149 P S++ TG + S+ G G Q+ P +G Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTT--SSYMSG----EGYQSLQSMMKTEGPSYGALPP 463 Query: 150 TFSPQIGLAQTQHHQQP-PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200 + P L H P PPP P P P PP PP P P+ P Sbjct: 464 AYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515 Score = 35.8 bits (81), Expect = 0.14 Identities = 58/261 (22%), Positives = 81/261 (31%), Gaps = 31/261 (11%) Query: 47 PEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS 106 P + P+L P P Q P P + PQQP Q+PA SP Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQ---QKDPQQPAQQQQPAQQPKKPSPQ 326 Query: 107 FGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166 S V +P + P P+I +T H P Sbjct: 327 PSSPRQVKRAVVV--------SPKEENKAAEPPP------------PKIPKIETTHPPLP 366 Query: 167 PP-PAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQ--RSAAAAYGHQPIMTSKPSSS 223 P P P +P A +A+PP P + P Q A A HQP Sbjct: 367 PAHPPPDRKPPLAAALGEAEPP----GPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP 422 Query: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVP 283 ++ + +S+ S +QS+ + +G L P + V P Sbjct: 423 PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNP 482 Query: 284 SPLNPISPLKKPFSSNVIAPP 304 P P+ P F I PP Sbjct: 483 PP-PPVPPPPASFPPPAIPPP 502 Score = 33.9 bits (76), Expect = 0.52 Identities = 46/183 (25%), Positives = 64/183 (34%), Gaps = 34/183 (18%) Query: 156 GLAQTQHH-----QQPP-----PPAPAPQPAQ------PAQPPQAQP--PQQRRSPASPS 197 G Q HH QQPP P P Q +Q P+QP Q P P Q++ PA Sbjct: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320 Query: 198 QAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSN 257 + P Q S+ +++ K + AA TH + A P Sbjct: 321 KKPSPQPSSPRQVKRAVVVSPKEENK------AAEPPPPKIPKIETTHPPLPPAHPPPDR 374 Query: 258 --PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSK 315 P +P V V +P P +P +P+ +P PP R P Sbjct: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHP-APVHQP-------PPLPHRPPPPPPS 426 Query: 316 SWM 318 S+M Sbjct: 427 SYM 429 Score = 31.6 bits (70), Expect = 2.6 Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 7/90 (7%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSF-- 83 P P A P + P P P +P PP P P + PGL Sbjct: 483 PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP 542 Query: 84 --HQPPQQPP---PPQEPAAPGASLSPSFG 108 + PP PP PP P P + P G Sbjct: 543 ASYPPPAVPPGGQPPVPPPIPPPGMPPVGG 572 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 59.7 bits (143), Expect = 9e-09 Identities = 79/291 (27%), Positives = 110/291 (37%), Gaps = 51/291 (17%) Query: 31 SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90 S E P++P ++ P PEE + SPAAA P P P P PP++P Sbjct: 995 STPEEPASPAAA-VPTPEEPT-----SPAAAVPTPEEPTSPAAAVP---------PPEEP 1039 Query: 91 -------PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI---TPVNGTMLFQNFP 140 P P+EP +P A++ T E+ TP T P Sbjct: 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1099 Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPA-PQPAQPAQPPQAQP-PQQRRSPASPSQ 198 P SP A ++P PA A P P +PA P A P P++ PA Sbjct: 1100 TPEEPT-----SPA---AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151 Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258 P SAA A + T + S+S A A A +AS A+ + + A S P+ Sbjct: 1152 TPEESASAAVA-----VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206 Query: 259 --WGGLQAGRDPRRAVGVG---VGVGVGVPSPLNPISP------LKKPFSS 298 L+ P +V + V +P P SP L++P SS Sbjct: 1207 AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257 Score = 53.1 bits (126), Expect = 8e-07 Identities = 69/285 (24%), Positives = 98/285 (34%), Gaps = 32/285 (11%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPA----LSPAAAPPAPNGPDKMQMESPLLPGL 81 P PE S A + P E P +AVP SPAAA P P E P P Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTP--------EEPASPAA 1122 Query: 82 SFHQP--PQQP----PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI---TPVNG 132 + P P P P P+EPA P ++ S + E+S TP Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182 Query: 133 TMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQA-QPPQQRR 191 P P + P A P +PA A P++ Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242 Query: 192 SPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAA 251 SPA+ S+AAA ++T + SS A + AS A++ N + + A Sbjct: 1243 SPAAAVPTLEEPTSSAAA-----VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297 Query: 252 WSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296 + P+ + A P V + P+ +SP+ PF Sbjct: 1298 AAVPTPEVAAIPAASVPTPEV---PAIPAAAVPPMEEVSPIGVPF 1339 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 59.3 bits (142), Expect = 1e-08 Identities = 63/243 (25%), Positives = 89/243 (36%), Gaps = 25/243 (10%) Query: 15 QPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQME 74 Q QQQQ+QQQQ Q ++ ++ P + P+P + A+P + P + Sbjct: 248 QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307 Query: 75 SPLLPGLSFHQPPQ---QPPPPQEPAAPGASLSPS----FGSTWSTGTTNAVEDSFFQGI 127 P+ PPQ QP Q A PG L F V+ Q Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367 Query: 128 TPVNGTMLFQNFPHHVN------PVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP 181 T V Q V P+ SP G PPPP P+PQP QP+ Sbjct: 368 TAVQTAQAAQMVAPGVQVSQSSLPMLS---SPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424 Query: 182 PQA--------QPPQQRRSPA-SPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAA 232 P + P SP+ PSQ+P R+ P + P + S+V + A + Sbjct: 425 PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484 Query: 233 AAA 235 + A Sbjct: 485 SQA 487 Score = 35.4 bits (80), Expect = 0.18 Identities = 37/136 (27%), Positives = 49/136 (36%), Gaps = 22/136 (16%) Query: 5 LLMDKSKTQPQPQQQQRQQQQPQ------PESSVSEAPSTPLSSETPKPEENSAVPALSP 58 +++ + QPQ QQQQ Q Q P VS++ LSS +P + + P Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411 Query: 59 AAAPPAPNGPDKM---QMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGT 115 P P P + S P S P P P Q P + +P S S G Sbjct: 412 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV---TARTPQNFSVPSPGP 468 Query: 116 TNAVEDSFFQGITPVN 131 N TPVN Sbjct: 469 LN----------TPVN 474 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 59.3 bits (142), Expect = 1e-08 Identities = 76/318 (23%), Positives = 108/318 (33%), Gaps = 26/318 (8%) Query: 11 KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPA-----LSPAAAPPAP 65 K P P + P + + TP ++ P P+ A P+ PAA PP+P Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996 Query: 66 NGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125 G P P P PP +P A+ P ST T + + S Sbjct: 997 KG-------GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS--P 1047 Query: 126 GITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPP--APA-PQPAQPAQPP 182 TP+ +P GG +P + A T PP P PA P P PP Sbjct: 1048 AATPLPKGAPTTPAATLPSPK-GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106 Query: 183 QAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSW 242 A PP + A+P AA + + + P + AA + ++ Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166 Query: 243 NTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV------GVGVPSPLN-PISPLKKP 295 + + P +P GGL A P+ A G+ PSP P +P P Sbjct: 1167 PPKGAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225 Query: 296 FSSNVIAPPKFPRAAPLT 313 S P+ AP T Sbjct: 1226 PSPKGGLATPSPKGAPTT 1243 Score = 57.4 bits (137), Expect = 4e-08 Identities = 82/325 (25%), Positives = 115/325 (35%), Gaps = 46/325 (14%) Query: 23 QQQPQPESSVSEAPSTPLS--SETPKPEENSAVP-------------ALSPAAAPPAPNG 67 Q + P S P TP+ S P E S +P A + + PP+P G Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863 Query: 68 PDKMQMESPLLP-GLSFHQPPQQPP---------PPQEPAAPGASLSPSFGSTWSTGTTN 117 +PL P G++ PP++ P P + PA P +P+ T S+ Sbjct: 864 APTPSAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT-SSSPKK 920 Query: 118 AVEDSFFQGITPVNGTMLFQNFPHHVNPVF--GGTFSPQIGLAQTQHHQQPPPP--APA- 172 A +GI P + + P P GG +P A T PP P PA Sbjct: 921 ARATPAPKGI-PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979 Query: 173 PQPAQPAQPPQAQPPQQRRSPASPSQ--APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230 P P PP A PP + PA+PS AP + P T P +S AA Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039 Query: 231 AAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPIS 290 + S +++ AP+ P L + P+ G P P S Sbjct: 1040 PPSPKGSPAAT-------PLPKGAPTTPAATLPS---PKGGPATPSLKGAPTPPAATPPS 1089 Query: 291 PLKKPFSSNVIAPPKFPRAAPLTSK 315 P P + + P P A P + K Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPK 1114 Score = 51.6 bits (122), Expect = 2e-06 Identities = 83/310 (26%), Positives = 110/310 (35%), Gaps = 41/310 (13%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQ 85 P P+++ + + L+ E PK + P+L PA PP D + S L P S Sbjct: 712 PSPQNTCAPLATLVLAPEIPKSVPS---PSLPPAGTPPGTKKVDGISHTSALAPVAS--- 765 Query: 86 PPQQPPPPQEPAAPGASL---------SPS-FGSTWSTGTTNAVEDSFFQG-ITPVNGTM 134 P++ P A+ AS SPS G + S T G TP+ Sbjct: 766 SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG--- 822 Query: 135 LFQNFPHHVNPVFGGTFSPQIGLA--------QTQHHQQPPPP--APAPQPAQPAQPPQA 184 N V+PV +F P+ L+ T H PP P AP P P P Sbjct: 823 ---NLSSPVSPV-EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878 Query: 185 QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244 P + S P+ + A Q S SSS A A A AS S Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938 Query: 245 HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPL-NPISPLKKPFSSNVIAP 303 + AA P +P GG A P+ A PSP P +P K + A Sbjct: 939 APTPPAA--TPPSPKGG-PATPSPKWA---PTPPAATPPSPKGGPATPSPKGAPTPPAAT 992 Query: 304 PKFPRAAPLT 313 P P+ P T Sbjct: 993 PPSPKGGPAT 1002 Score = 50.4 bits (119), Expect = 5e-06 Identities = 81/322 (25%), Positives = 109/322 (33%), Gaps = 40/322 (12%) Query: 26 PQPESSVSEAPSTPLS--------SETPKP--------EENSAVPALSPAAAPPAPNGPD 69 P P+ + + + TPLS ETP P +E A PA A A + Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918 Query: 70 KMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGST-WSTGTTNAVEDSFFQGIT 128 K +P G+ P+ P P P P+ S W+ A S G Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-- 976 Query: 129 PVNGTMLFQNFPHHVNPVF--GGTFSPQIGLAQTQHHQQPPPP----APAPQPAQPAQPP 182 P + P P GG +P A T PP P A P P + PP Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036 Query: 183 QAQPPQQRRSPAS---PSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239 A PP + SPA+ P AP + + P S + + AA + A+ Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT 1096 Query: 240 SSWNTHQSVNAAWSAPSNPWGGL-----QAGRDPRRAVGVGVGVGVGVPSPLN-PISPLK 293 S AA P +P GGL + A G+ P P P +P Sbjct: 1097 PSPKGAPMPPAA--TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154 Query: 294 KPFS--SNVIAPPKFPRAAPLT 313 P S + PP P+ AP T Sbjct: 1155 TPPSPKGGLATPP--PKGAPTT 1174 Score = 50.4 bits (119), Expect = 5e-06 Identities = 74/315 (23%), Positives = 106/315 (33%), Gaps = 35/315 (11%) Query: 26 PQPESSVSEAPSTPLSSE----TPKPEENSAVPALSPA------AAPPAPNGPDKMQMES 75 P P+ + + +TP S + TP P+ PA +P A PP P+ + Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294 Query: 76 PLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTML 135 P G PP+ P P P SP T AV +G TP Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-TP------ 1347 Query: 136 FQNFPHHVNPVFGGTFSPQ-----IGLAQTQHHQQPP---PPAPAPQPAQPAQPPQAQPP 187 P GG +P A T H+ P PP+P PA P+ P+ P Sbjct: 1348 --TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPT 1403 Query: 188 QQRRSPASPSQAPYA----QRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243 P SP +AP + +A + G P S A +A + SS Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463 Query: 244 THQSVNAAWSAPSNPWGGLQ--AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVI 301 +P P Q P++A +G + P SP + P + + Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523 Query: 302 APPKFPRAAPLTSKS 316 P P A L+ K+ Sbjct: 1524 RDPIAPTATLLSKKT 1538 Score = 48.1 bits (113), Expect = 3e-05 Identities = 68/299 (22%), Positives = 101/299 (33%), Gaps = 57/299 (19%) Query: 26 PQPESSVSEAPSTPLSSE----TPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGL 81 P P+ + + +TP S + TP P+ +PAA PP+P G P P Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKG----APTTPAATPPSPKG-------GPATP-- 1258 Query: 82 SFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPH 141 PP+ P P PAA SL + G N P Sbjct: 1259 ----PPKGAPTP--PAATPPSLKGGLATPPHKGAPN----------------------PA 1290 Query: 142 HVNPVFGGTFSPQIGLAQTQHHQQPPPPA---PAPQPAQPAQPPQAQPPQQRRSPASPSQ 198 V P SP+ G A + P PPA P+P+ + PP+ P +P SP Sbjct: 1291 VVTPP-----SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345 Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258 P + ++ G +SK + A + + S ++ + P++P Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405 Query: 259 WGGLQAGRDPRRAVGVGV-GVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316 P++A V G PS + P P S P+ P T S Sbjct: 1406 ---AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461 Score = 46.6 bits (109), Expect = 8e-05 Identities = 71/322 (22%), Positives = 104/322 (32%), Gaps = 26/322 (8%) Query: 14 PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM 73 P P+Q P+ +P P+ PA +P + P P Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962 Query: 74 ESPLLPGLSFHQP---PQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPV 130 +P P + P P P P P P A+ G + A +P Sbjct: 963 PTP--PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP- 1019 Query: 131 NGTMLFQNFPHHVN-PVFGGTFSPQIGLAQTQHHQQPPP------PAPAPQPAQPA---- 179 G+ FP + P SP+ A T + P P+P PA P+ Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079 Query: 180 -QPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSA 238 PP A PP + PA+PS AA + + + P + AA + Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139 Query: 239 SSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV------GVGVPSPLN-PISP 291 ++ + + P +P GGL A P+ A G+ PSP P +P Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198 Query: 292 LKKPFSSNVIAPPKFPRAAPLT 313 P S P+ AP T Sbjct: 1199 AATPPSPKGGLATPSPKGAPTT 1220 Score = 42.7 bits (99), Expect = 0.001 Identities = 42/194 (21%), Positives = 67/194 (34%), Gaps = 40/194 (20%) Query: 12 TQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPK-----PEENSAVPALSPAAAPPAPN 66 T P P++ +Q SS +AP+TP P P VPA + P Sbjct: 1471 TPPSPKEPPAPKQVAT-SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529 Query: 67 GPDKMQMESP--LLPGLSFHQPPQQPPPPQE-PAAPGASLSPSFGSTWSTGTTNAVEDSF 123 + ++P L P + P P P++ PA P +P+ S+ + AV S Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589 Query: 124 FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183 ++G ++ PP +P P + PP Sbjct: 1590 YKGAPSPKELLI-------------------------------PPAVTSPSPKEAPTPPA 1618 Query: 184 AQPPQQRRSPASPS 197 PP + PA+P+ Sbjct: 1619 VTPPSPEKGPATPA 1632 Score = 42.4 bits (98), Expect = 0.001 Identities = 59/252 (23%), Positives = 87/252 (34%), Gaps = 43/252 (17%) Query: 11 KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVP-----ALSPAAAPPAP 65 K P P + P +S + TP ++ P P+ + P PA PP+P Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343 Query: 66 NGPDKMQMESPLLPG----------------LSFHQ--PPQQPPPPQE-PAAPGASLSPS 106 G + +P G H+ P PP P+ PA P P+ Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403 Query: 107 FGSTWSTGTTNAVEDSFFQ--GITPVNGTMLFQNFPHHVNPV----FGGTFSPQIGLAQT 160 + A + TP G + P V PV T +P+ G A Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLT----PPAVTPVSLKKAPATSAPKGGPATP 1459 Query: 161 QHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKP 220 + P PA P P +PP P+Q + +SP +AP + A G + P Sbjct: 1460 S--SKGDPTLPAVTPPSPKEPP---APKQVATSSSPKKAP----ATPAPMGAPTLPAVIP 1510 Query: 221 SSSSAVAAAAAA 232 SS V A ++ Sbjct: 1511 SSPKEVPATPSS 1522 Score = 42.4 bits (98), Expect = 0.001 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 35/210 (16%) Query: 36 PSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPP-- 93 P +P PK S+ P +PA PAP G +P LP + P + P P Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPAT--PAPMG-------APTLPAVIPSSPKEVPATPSS 1522 Query: 94 -QEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFS 152 ++P AP A+L T T A +++ V P + Sbjct: 1523 RRDPIAPTATLLSK-----KTPATLAPKEALIPPAMTVPSPKKTPAIP-----------T 1566 Query: 153 PQIGLAQTQHHQQPPPPAP-------APQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRS 205 P+ A + PPA AP P + PP P + +P P+ P + Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626 Query: 206 AAAAYGHQPIMTSKPSSSSAVAAAAAAAAA 235 A + TS P + S++ + + A+ Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656 Score = 36.2 bits (82), Expect = 0.11 Identities = 57/240 (23%), Positives = 72/240 (30%), Gaps = 58/240 (24%) Query: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET--PKPEENSAVPALSPA-----A 60 D SKT + P S + P T + E PKPE S A SP A Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803 Query: 61 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120 P P P K Q P PGL P +P AP A E Sbjct: 1804 PSPVPTLPPKQQF-LPSSPGLVLESP-------SKPLAP------------------ADE 1837 Query: 121 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA- 179 D I P P+ GG + L + P P P QP Sbjct: 1838 DELLPLIPP--------------EPISGGVPFQSV-LVNMPTPKSAGIPVPTPSAKQPVT 1882 Query: 180 ---------QPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230 P+ ++ + AQ +AAA +P+ +K S S A A Sbjct: 1883 KNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA 1942 Score = 34.3 bits (77), Expect = 0.40 Identities = 75/341 (21%), Positives = 115/341 (33%), Gaps = 59/341 (17%) Query: 4 DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET--------------PKPEE 49 + L+ + T P P+ + P P+ EAP+TP S E P P+E Sbjct: 1546 EALIPPAMTVPSPK---KTPAIPTPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598 Query: 50 NSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSF-G 108 + PA P+P E+P P ++ PP P PA G SP Sbjct: 1599 L----LIPPAVTSPSPK-------EAPTPPAVT---PPSPEKGPATPAPKGTPTSPPVTP 1644 Query: 109 STWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNP-------VFGGTFSPQIGLAQTQ 161 S+ T+ + G T + + P P V S I A T+ Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQAS---KGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701 Query: 162 HHQQ-------PPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQP 214 Q PP P P ++ P + P + A+ A+ P Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761 Query: 215 IMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAP-SNPWGGLQAGRDPRRAVG 273 + + +S+ + AAA S+ SV+AA S P S P P + Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESA-----SVSAAPSPPVSLPLAPSPVPTLPPKQQF 1816 Query: 274 VGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTS 314 + G+ + SP P++P + +I P P S Sbjct: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857 Score = 32.0 bits (71), Expect = 2.0 Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%) Query: 166 PPPPAPAPQPAQPAQPPQAQP-PQQRRSPASPSQAPYAQRSAAAAY---------GHQPI 215 PPP +PAPQ + QA P P ++P + P+ Q S+ A P Sbjct: 46 PPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN 105 Query: 216 MTSKPSSSSAVAAAAAAAA 234 + P S +A+A A+ A Sbjct: 106 LIGPPISPAALALASPMIA 124 Score = 29.6 bits (65), Expect = 9.9 Identities = 75/301 (24%), Positives = 106/301 (35%), Gaps = 75/301 (24%) Query: 31 SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPL--------LPGLS 82 S S +P PLS PE A +L P P G M SPL + S Sbjct: 575 STSSSPEIPLS-----PEATLAKKSLGE----PLPIGKPASSMTSPLGVNSSASVIKTDS 625 Query: 83 FHQPPQQPPP-------------PQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG--- 126 + P P P E A P A ++P+ ST TT A F +G Sbjct: 626 YAGPDSAGPLLKSSLITPTVAAFPLESADP-AGVAPTTAKGTSTYTTTA--SPFLEGTVS 682 Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP 186 + P N +PV GT + L + P AP+PQ Sbjct: 683 LAPKN------------HPVKEGTLTT---LPLVPTASENCPVAPSPQNTCAPLATLVLA 727 Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAA--------SSA 238 P+ +S SPS P P T K S +A A A++ S A Sbjct: 728 PEIPKSVPSPSLPP----------AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777 Query: 239 SSSWNTHQSVNAAWSAPSNPWG---GLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKP 295 S++ ++ ++ +PS P G Q R P + G +G S +P+SP++ Sbjct: 778 SATASSKGTLTYLADSPS-PLGVSVSPQTKRPPTKKGSAGPDTPIGNLS--SPVSPVEAS 834 Query: 296 F 296 F Sbjct: 835 F 835 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 58.5 bits (140), Expect = 2e-08 Identities = 77/302 (25%), Positives = 102/302 (33%), Gaps = 40/302 (13%) Query: 14 PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPAL---------SPAAAPPA 64 P P + + P SVS PS P P P+ +P + P A+ PA Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851 Query: 65 PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124 P P Q PL P QPP+ P PP P ++ S S+ ++ A S F Sbjct: 852 PTAPGPPQ--PPLRPQ---SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906 Query: 125 QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184 Q FP P T P + L + PP P P+ Q P Sbjct: 907 Q-----------LQFPPSQGPHKSPTPPPTLHLVP----EPAAPPPPPPRTFQMVTTPFP 951 Query: 185 QPPQQRRSPASPSQAP---YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSS 241 PQ + Q P Q A A TS +S A+ + A S + + Sbjct: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011 Query: 242 WNTHQSVNAAWSAPSNP-----WGGLQAGRDPRRAVGVGVGVGVGVPSPL---NPISPLK 293 +H A +A P A P V G G PS L + +S LK Sbjct: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071 Query: 294 KP 295 KP Sbjct: 1072 KP 1073 Score = 49.3 bits (116), Expect = 1e-05 Identities = 58/209 (27%), Positives = 79/209 (37%), Gaps = 44/209 (21%) Query: 28 PESSVSEAPSTPLSSET---PKPEENSAVPALSP---AAAP---PAPNGPDKMQMESPLL 78 P + AP+TP++ P+ ++ A PA +P AAAP P P+ + ++PL Sbjct: 727 PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL- 785 Query: 79 PGLSFHQPPQQPP-PPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQ 137 G S H P P PP P + S+S P + L Sbjct: 786 -GDSPHLPSPHPTRPPSRPPSRPQSVS-----------------------RPPSEPPLHP 821 Query: 138 NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP---PQAQPPQQRRSPA 194 P P G F + Q Q PP PAP P QP PQ+QPP+ PA Sbjct: 822 CPPPQAPPTLPGIF-----VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA 876 Query: 195 SPSQAPYAQRSAAAAYGHQPIMTSKPSSS 223 P P + SA A+ P+ S Sbjct: 877 -PHLPPSSTSSAVASSSETSSRLPAPTPS 904 Score = 48.9 bits (115), Expect = 2e-05 Identities = 54/206 (26%), Positives = 71/206 (34%), Gaps = 45/206 (21%) Query: 15 QPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM- 73 QPQ QQ Q P P+++ +TP S V P+A P A D +QM Sbjct: 641 QPQAQQ-PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF 699 Query: 74 ------ESPLL---PGLSF-------HQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTN 117 + PL P LS PP Q P P P A GA L P + + Sbjct: 700 LPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS----QAS 755 Query: 118 AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP---PPPAPAPQ 174 P+ G G + SP + HQ P P P+P Sbjct: 756 PAPAPQIPAAAPLKGP--------------GPSSSPSL------PHQAPLGDSPHLPSPH 795 Query: 175 PAQPAQPPQAQPPQQRRSPASPSQAP 200 P +P P ++P R P+ P P Sbjct: 796 PTRPPSRPPSRPQSVSRPPSEPPLHP 821 Score = 47.0 bits (110), Expect = 6e-05 Identities = 80/304 (26%), Positives = 105/304 (34%), Gaps = 38/304 (12%) Query: 28 PESSVS--EAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQ 85 P S+V+ P + TP A P L+ AP AP + +PL GL Q Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA-----VSTPLPLGL---Q 640 Query: 86 PPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNP 145 PQ PPQ P A+ + S G ++ E T + + Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQ--DSLQM 698 Query: 146 VFGGTFSPQIGLAQTQHHQQP-------PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQ 198 S Q A+ H P PPPA P PA P PQ S ASP+ Sbjct: 699 FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAP 758 Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTH---------QSVN 249 AP Q AAA P+ PSSS ++ A + S T QSV+ Sbjct: 759 AP--QIPAAA-----PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS 811 Query: 250 AAWSAPSNPWGGLQAGRDPRRAVGVGVGVG-VGVPSPLNPISPLKKPFSSNVIAPPKFPR 308 S P P + P G+ V +GVP P + +P + P P Sbjct: 812 RPPSEP--PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP 869 Query: 309 AAPL 312 PL Sbjct: 870 EGPL 873 Score = 39.7 bits (91), Expect = 0.010 Identities = 54/244 (22%), Positives = 87/244 (35%), Gaps = 30/244 (12%) Query: 1 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60 +Q+ L + + P P Q +P+S E P P P ++ + ++ Sbjct: 837 IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSS 896 Query: 61 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPP---PQEPAAPGASLSPSFGSTWSTGTTN 117 PAP P Q++ P P H+ P PP EPAAP +F + Sbjct: 897 RLPAPT-PSDFQLQFP--PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPAL 953 Query: 118 AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQ 177 + + V ++ Q N G +PQ + P +PA Sbjct: 954 PQPKALLERFHQVPSGIILQ------NKAGGAPAAPQTSTS------LGPLTSPAASVLV 1001 Query: 178 PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237 Q P +P +PS AP + AA G P++ P+ + A A+ + Sbjct: 1002 SGQAPSG-------TPTAPSHAP--APAPMAATGLPPLL---PAENKAFASNLPTLNVAK 1049 Query: 238 ASSS 241 A+SS Sbjct: 1050 AASS 1053 Score = 38.1 bits (87), Expect = 0.028 Identities = 50/217 (23%), Positives = 83/217 (38%), Gaps = 32/217 (14%) Query: 1 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPL--SSETPKPEENSAVPALSP 58 M D + + + KT +Q +++P S S + P+ SSE + + + + +P Sbjct: 1174 MIDRMFIQEEKTT-LALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAP 1232 Query: 59 AAAP-PAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTN 117 A+ P P+ P K+ + G P A +SLS S S+ + + + Sbjct: 1233 GASTQPPPHLPTKLVIRHGGAGG----------SPSVTWARASSSLSSSSSSSSAASSLD 1282 Query: 118 AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH-------HQQPPPPA 170 A ED G P + + + GL++ H HQ PPPPA Sbjct: 1283 ADED----GPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPA 1338 Query: 171 PAPQPAQPAQPPQAQPPQQRRS-------PASPSQAP 200 P +PP PP + + PA+P + P Sbjct: 1339 TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKP 1375 Score = 36.6 bits (83), Expect = 0.081 Identities = 96/401 (23%), Positives = 126/401 (31%), Gaps = 116/401 (28%) Query: 13 QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAV----PALSPAAAPPAPNGP 68 +P QQ + Q + +A + S P P + V PA + AAPP P G Sbjct: 383 EPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGA 442 Query: 69 DKMQMESPLL-PGLSFHQPPQQPPPPQE----PAAPGASLSPSFGSTWST--GTTNAVED 121 M LL G S P Q P Q P AP L + + G A Sbjct: 443 LSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAA 502 Query: 122 SFFQGITPVNGTMLFQNF--PHHVNPVFG---------------------GTFSPQIGLA 158 G N + QN P + PV F + LA Sbjct: 503 PHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLA 562 Query: 159 --QTQHHQQPPPPAPAP------------------------QPAQPA------------Q 180 QP P PA QPA PA Q Sbjct: 563 AGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQ 622 Query: 181 P-PQAQP------------PQQRRSP-------ASPSQAPYAQRSAAAAYGHQPIMTSKP 220 P PQA P PQ ++ P A+P QA Q S A + I+ +P Sbjct: 623 PAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682 Query: 221 SSSSAVAAAAAAA--------AASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAV 272 S++ A + + S+ H SV A+ + P +DP A Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP-----PAQDPAPAT 737 Query: 273 GVGVGVGVGVPSPLNPISPLKKPFSSNVIAP-PKFPRAAPL 312 V G G+G +P + SP AP P+ P AAPL Sbjct: 738 PVAKGAGLGPQAPDSQASP----------APAPQIPAAAPL 768 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 58.2 bits (139), Expect = 3e-08 Identities = 76/265 (28%), Positives = 104/265 (39%), Gaps = 32/265 (12%) Query: 24 QQPQPESS----VSEAPSTPLSSETPKPEENSAVPALSPAAAP------PAPNGPDKMQM 73 Q+P P S V P+ P + P PE ++ A PAAA PAP GP K Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162 Query: 74 ESPLL----PGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITP 129 + L PG P P P +PA PGA+ + + GS + +A + ++ Sbjct: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLN-GSAALLNSHHAAAPA----VSL 217 Query: 130 VN-GTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQ 188 VN G P P P +G A P P AP+P A P A PP Sbjct: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP-----PAPAAPSPPAAPAPAAPAAAPPP 272 Query: 189 QRRSPASPSQAP-YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS 247 +PA+ ++ P + AA P ++ S+ A A A AA A S Sbjct: 273 PPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG 332 Query: 248 VNAAWSAPSNPWGGLQAGRDPRRAV 272 AA AP G++A P+R V Sbjct: 333 AAAAAPAP-----GVKA-ESPKRVV 351 Score = 43.5 bits (101), Expect = 7e-04 Identities = 53/222 (23%), Positives = 86/222 (38%), Gaps = 15/222 (6%) Query: 25 QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84 QP P ++ + AP+ + +E+PK V A PAA A +GP + P + Sbjct: 328 QPGPGAAAA-APAPGVKAESPK----RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382 Query: 85 QPPQQPPPPQEPAAPGASLSPSFGSTWS--TGTTNAVEDSFFQGITPVNGTMLFQNFPHH 142 P PP P P + G+ + T A +TP P + Sbjct: 383 LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQN 442 Query: 143 VNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQP-AQPPQAQPPQQRRSPASPSQA 199 + P + L ++++ Q P A A AQ AQP P+ PA+P+ A Sbjct: 443 PTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPR----PATPTSA 498 Query: 200 PYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSS 241 P Q S A G PI+ + + ++ + + A S++ Sbjct: 499 PPVQISTVQAPG-TPIIARQVTPTTIIKQVSQAQTTVQPSAT 539 Score = 38.9 bits (89), Expect = 0.016 Identities = 43/149 (28%), Positives = 55/149 (36%), Gaps = 14/149 (9%) Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP----PQAQ-PPQQRRSPASPSQ 198 N V G+ + G + P AP P PA A+P PQ PP RR Sbjct: 60 NHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGP 119 Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258 AP A + +P S + V AAAA AA + + + AA +A + P Sbjct: 120 APPAAKL-------RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172 Query: 259 WGGLQAGRDPRRAVGVGVGVGVGVPSPLN 287 G G P G G G G LN Sbjct: 173 GPG--PGPGPGPGPGPGKPAGPGAAQTLN 199 Score = 34.3 bits (77), Expect = 0.40 Identities = 50/210 (23%), Positives = 65/210 (30%), Gaps = 57/210 (27%) Query: 23 QQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLS 82 Q P ++ AP+ P P P A PA +P PPAP + Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAP----AAPAAAPPPPPPAP---------------AT 279 Query: 83 FHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFP 140 +PP P PP PA P + + + GS G P Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSA---------------GAAPAPA-------- 316 Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200 P GG QP P A A PA + + Q PA+ + A Sbjct: 317 ----PAAGGPAGVS---------GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363 Query: 201 YAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230 S AA+ P M S +AV A Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVPPPA 393 Score = 32.0 bits (71), Expect = 2.0 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 7/87 (8%) Query: 19 QQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLL 78 QQ QQQ P P S + A + + S + + ++ A PP + + P Sbjct: 676 QQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPV------LSLTQPTQ 729 Query: 79 PGLSFHQPPQQPPPPQEPAAPGASLSP 105 G+ P P Q+P PGA + P Sbjct: 730 VGVGKQGQP-TPLVIQQPPKPGALIRP 755 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 57.4 bits (137), Expect = 4e-08 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%) Query: 8 DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62 D QQQ Q QP Q + V+ APS+ P + + P P + A+ P +P Sbjct: 166 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 225 Query: 63 PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116 A P++ Q + +P Q PQ+PP P P +P L P GS Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 285 Query: 117 NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169 + + P ++ H P PQ +G + + Sbjct: 286 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345 Query: 170 APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224 PA Q A Q QPP+ QP P P P Q A A+ H P + S PS S Sbjct: 346 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 404 Query: 225 AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271 + A A SS +TH +A S+P+ P G Q+ P Sbjct: 405 -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463 Query: 272 VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316 P+ L+ ++P + PF+ + P P P T S Sbjct: 464 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 500 Score = 41.2 bits (95), Expect = 0.003 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%) Query: 18 QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74 Q Q QQP E + P PL+ KP + +P L A PP +GP M Sbjct: 350 QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406 Query: 75 SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126 + L P LS H PP PPP + P + PS G T + Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 456 Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182 QN P P T HQ P P A P P PP Sbjct: 457 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495 Query: 183 -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211 + PP P + +Q P S AAA G Sbjct: 496 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 523 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 57.4 bits (137), Expect = 4e-08 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%) Query: 8 DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62 D QQQ Q QP Q + V+ APS+ P + + P P + A+ P +P Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 63 PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116 A P++ Q + +P Q PQ+PP P P +P L P GS Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839 Query: 117 NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169 + + P ++ H P PQ +G + + Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899 Query: 170 APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224 PA Q A Q QPP+ QP P P P Q A A+ H P + S PS S Sbjct: 900 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 958 Query: 225 AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271 + A A SS +TH +A S+P+ P G Q+ P Sbjct: 959 -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017 Query: 272 VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316 P+ L+ ++P + PF+ + P P P T S Sbjct: 1018 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 1054 Score = 41.2 bits (95), Expect = 0.003 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%) Query: 18 QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74 Q Q QQP E + P PL+ KP + +P L A PP +GP M Sbjct: 904 QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 75 SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126 + L P LS H PP PPP + P + PS G T + Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 1010 Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182 QN P P T HQ P P A P P PP Sbjct: 1011 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 183 -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211 + PP P + +Q P S AAA G Sbjct: 1050 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 1077 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 57.4 bits (137), Expect = 4e-08 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%) Query: 8 DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62 D QQQ Q QP Q + V+ APS+ P + + P P + A+ P +P Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 63 PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116 A P++ Q + +P Q PQ+PP P P +P L P GS Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839 Query: 117 NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169 + + P ++ H P PQ +G + + Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899 Query: 170 APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224 PA Q A Q QPP+ QP P P P Q A A+ H P + S PS S Sbjct: 900 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 958 Query: 225 AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271 + A A SS +TH +A S+P+ P G Q+ P Sbjct: 959 -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017 Query: 272 VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316 P+ L+ ++P + PF+ + P P P T S Sbjct: 1018 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 1054 Score = 41.2 bits (95), Expect = 0.003 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%) Query: 18 QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74 Q Q QQP E + P PL+ KP + +P L A PP +GP M Sbjct: 904 QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 75 SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126 + L P LS H PP PPP + P + PS G T + Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 1010 Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182 QN P P T HQ P P A P P PP Sbjct: 1011 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 183 -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211 + PP P + +Q P S AAA G Sbjct: 1050 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 1077 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 57.4 bits (137), Expect = 4e-08 Identities = 68/263 (25%), Positives = 96/263 (36%), Gaps = 43/263 (16%) Query: 14 PQPQQQQRQQQQPQPESSVSEAPSTPLSS--------------ETPKPEENSAVPALSPA 59 P P + P P S S P+ P SS + + + L P Sbjct: 20 PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPH 79 Query: 60 AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119 PP P P P++PG + QPPPP P PG +LS + + Sbjct: 80 HLPPPPLPPP------PVMPGGGYGD--WQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131 Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179 D G+ P+ P PV G++ P +Q + PP P P+ P + Sbjct: 132 RDGP-PGLVPME-----LESPPESPPVPPGSYMPP-----SQSYMPPPQPPPSYYPPTSS 180 Query: 180 QP--PQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237 QP P AQP SPSQ+P +Q A + +S S S + ++ AS Sbjct: 181 QPYLPPAQP--------SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232 Query: 238 ASSSWNTHQSVNAAWSAPSNPWG 260 + S +S A PS P G Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPG 255 Score = 50.4 bits (119), Expect = 5e-06 Identities = 62/262 (23%), Positives = 89/262 (33%), Gaps = 30/262 (11%) Query: 7 MDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPN 66 M +++ Q + Q + Q ++S P S+ P P P L P+ PP Sbjct: 489 MKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPP--- 545 Query: 67 GPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSF-GSTWSTGTTNAVEDSFFQ 125 + P LP PP PPP P+ P + P S S G + Sbjct: 546 ------VMPPALPATV--PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLS 597 Query: 126 GITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQ 185 P P P T P + PPP P P Q P Sbjct: 598 SAGPP---------PVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTA 648 Query: 186 PPQQRRSPASPSQAPYAQRSA----AAAYGHQPIMTSKPSSSSA-----VAAAAAAAAAS 236 P S + SQ P R A ++G P T P SA V + A + ++ Sbjct: 649 APVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSA 708 Query: 237 SASSSWNTHQSVNAAWSAPSNP 258 SS+++ Q + + +APS P Sbjct: 709 LPYSSFSSDQGLGESSAAPSQP 730 Score = 50.1 bits (118), Expect = 7e-06 Identities = 61/233 (26%), Positives = 86/233 (36%), Gaps = 54/233 (23%) Query: 80 GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQ-- 137 G S H PP PPP A P AS P + S+ T A S F + L Q Sbjct: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYS---SSTTPAAPSSSGFMSFREQHLAQLQQLQ 65 Query: 138 ----------NFPHHVNP--------VFGGTFS----------PQIGLA----------- 158 PHH+ P + GG + P G A Sbjct: 66 QMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH 125 Query: 159 QTQHHQQPPPPAPAPQ-----PAQPAQPPQA-QPPQQRRSPASPSQAPYAQRSAAAAY-- 210 Q HHQ+ PP P P P PP + PP Q P Y +++ Y Sbjct: 126 QMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP 185 Query: 211 GHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS--VNAAWSAPSNPWGG 261 QP + P S S +A + +++SS+S S+ +H + ++ ++PS P G Sbjct: 186 PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG 238 Score = 39.3 bits (90), Expect = 0.012 Identities = 46/205 (22%), Positives = 69/205 (33%), Gaps = 28/205 (13%) Query: 18 QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74 ++Q++Q Q + + L + + + S+ P + P PP P G + Sbjct: 1467 REQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIV 1526 Query: 75 SPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS----FGSTWSTGTTNAVEDSFFQGITPV 130 P P P +PP P P P L P T + EDSF+ G+ Sbjct: 1527 RPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFY-GLWDT 1585 Query: 131 NGTM-LFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQ 189 N L F + P + H PPP P P PP ++PP Sbjct: 1586 NDEQGLNSEFKSETAAIPSAPVLPPPPV-----HSSIPPPGPVPM----GMPPMSKPPPV 1636 Query: 190 RR----------SPASPSQAPYAQR 204 ++ S Q PY +R Sbjct: 1637 QQTVDYGHGRDISTNKVEQIPYGER 1661 Score = 34.7 bits (78), Expect = 0.31 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 24/215 (11%) Query: 13 QPQPQQQQRQQQQPQPESSVSEAPSTP----------LSSETPKPEENSAVPALSPAAAP 62 QP P Q Q P S S + S+ L S P S + S AP Sbjct: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP 247 Query: 63 PAPNGPDKMQ---MESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119 P P+ P + + PL G QQ P+ P W ++ Sbjct: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD--PSTMTPQEQQQYWYRQHLLSL 305 Query: 120 EDSFFQGITP-VNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQP 178 + + G ++ ++ P V + Q+ + + PPP P P Sbjct: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365 Query: 179 AQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQ 213 + PQ++ P++ A Q AAAA+ Q Sbjct: 366 PEEPQSEDPEE--------DARLKQLQAAAAHWQQ 392 Score = 33.9 bits (76), Expect = 0.52 Identities = 40/185 (21%), Positives = 65/185 (35%), Gaps = 31/185 (16%) Query: 167 PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAV 226 PPP P P+ P PP S +S P + ++ G P++ SS+A Sbjct: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615 Query: 227 AAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPL 286 SSA+ P P G+ G P+ +P+ Sbjct: 616 PPVMPLPPLSSAT-------------PPPGIPPPGVPQGIPPQLTA-----------APV 651 Query: 287 NPISPL------KKPFSSNVIAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRP 340 P S +KP + + P F A P T ++ +A ++ N+ P + P Sbjct: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQ-SAGPSEQVNSKAPLSKSALP 710 Query: 341 YDTFN 345 Y +F+ Sbjct: 711 YSSFS 715 Score = 29.6 bits (65), Expect = 9.9 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 15/99 (15%) Query: 8 DKSKTQPQPQQQQRQQQ-----QPQPESSVSEAPSTPL-SSETPKP-EENSAVPALSPAA 60 D S PQ QQQ +Q Q + + + P+ + +TP+P +E VPA S Sbjct: 284 DPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV- 342 Query: 61 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAP 99 P+ E P LP + PP PP + P Sbjct: 343 -------PESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374 >gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] Length = 609 Score = 56.6 bits (135), Expect = 8e-08 Identities = 59/186 (31%), Positives = 77/186 (41%), Gaps = 39/186 (20%) Query: 9 KSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAP-PAPNG 67 K++ Q Q QQQQ+QQQQ Q + + S AP VP + PA P PAP G Sbjct: 425 KAQQQQQQQQQQQQQQQQQQQQAASVAP----------------VPTMPPALQPFPAPVG 468 Query: 68 P-DKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS-----FGSTWSTGTTNAVED 121 P D + ++ PP PP PA PG P G T S NA Sbjct: 469 PFDAAPAQ------VAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCS 522 Query: 122 SFFQGITPVNGTMLFQ--NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179 + + P T+L + FP P G+ A+ + + P PP PAP PA Sbjct: 523 A--AQLQPQPATLLGKAGAFPPPAIPSAPGS------QARPRPNGAPWPPEPAPAPAPEL 574 Query: 180 QPPQAQ 185 P +AQ Sbjct: 575 DPFEAQ 580 Score = 30.4 bits (67), Expect = 5.8 Identities = 63/259 (24%), Positives = 79/259 (30%), Gaps = 47/259 (18%) Query: 59 AAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNA 118 +A PAP P P G S P PP PG +PS W + Sbjct: 373 SAGAPAPGPP-------PATTGTSAWGEPSVPPAAA--FQPGHKRTPSEAERWLEEVSQV 423 Query: 119 VEDSFFQ------------------GITPVNGTM--LFQNFPHHVNPVFGGTFSPQIGLA 158 + Q + PV TM Q FP V P + L Sbjct: 424 AKAQQQQQQQQQQQQQQQQQQQQAASVAPVP-TMPPALQPFPAPVGPFDAAPAQVAVFL- 481 Query: 159 QTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTS 218 PPP P P PA P PP R + + + +A QP Sbjct: 482 --------PPPHMQP-PFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQP---- 528 Query: 219 KPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV 278 +P++ A A A SA S + A W P P DP A + Sbjct: 529 QPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPW--PPEPAPAPAPELDPFEAQWAALEG 586 Query: 279 GVGVPSPLNPIS-PLKKPF 296 V P NP S L+K F Sbjct: 587 KATVEKPSNPFSGDLQKTF 605 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 56.2 bits (134), Expect = 1e-07 Identities = 99/431 (22%), Positives = 142/431 (32%), Gaps = 102/431 (23%) Query: 4 DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET---PKPEENSAVPALSPAA 60 D+ D T P + S +S+ P+ P P P+ + P A+ Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182 Query: 61 APPAPNGPDKMQMESPLLPGLS--FHQPPQQPPP----------------PQEPAAPGAS 102 P P+ +P+ P S F PP PPP P P GA+ Sbjct: 183 FEPHPS-VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241 Query: 103 LS---PSFGSTWSTGTTN-AVEDSFFQGI-------TPVNGTMLFQ-----NFPH----- 141 S P+ G TT +V S G TPV G L NFPH Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301 Query: 142 ----HVNPVFGGTFSPQ-IGLAQTQHHQQPP----------PPAPAPQPAQPAQPPQAQP 186 + P+ + SP +G H P PP P P A P + P Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-APSPHSLP 360 Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQ 246 P +PA P + PY SSS+ ++AAA++++SS+SSS + Sbjct: 361 PASSSAPAPPMRFPY--------------------SSSSSSSAAASSSSSSSSSSASPFP 400 Query: 247 SVNAAWSAPSN--PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPP 304 + A S P + P L P P P P + +S PP Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQP--------------PKYTQPSLPSQAVWSQGPPPPP 446 Query: 305 KFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPL 364 + R L + S F G P T + H + + + Sbjct: 447 PYGR---LLANSNAHPGPFPPSTGAQ----STAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 365 KGKHYPPSGPP 375 + +H+ SGPP Sbjct: 500 QQQHHGNSGPP 510 Score = 50.8 bits (120), Expect = 4e-06 Identities = 71/287 (24%), Positives = 98/287 (34%), Gaps = 39/287 (13%) Query: 13 QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQ 72 Q Q QQQQ+QQQQ Q + P P P E + P A P+ + Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS------LG 537 Query: 73 MESPLLPGLSFHQPPQQPPPPQE-------PAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125 P PG P PPP + P P S S + S+ S G+ S Q Sbjct: 538 SLRPYPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592 Query: 126 GITPVNGTMLFQNFP------HHVNPVFGGTFSPQIGLAQTQHHQQPPP---PAPAPQPA 176 G P F P ++ V S G +T PPP AP+P Sbjct: 593 G--PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPPYGKRAPSPGAY 649 Query: 177 QPAQPP---QAQPPQQRRSP------ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227 + A PP PP R SP P + + G P+ + PS ++ Sbjct: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709 Query: 228 AAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274 AA A+ S+ Q + P +P ++ P + V V Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756 Score = 40.8 bits (94), Expect = 0.004 Identities = 55/235 (23%), Positives = 76/235 (32%), Gaps = 41/235 (17%) Query: 14 PQPQQQQRQQQQ----PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69 P P Q Q P SS + + ST S S P +P PP P Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609 Query: 70 KMQMESPLLP-------GLSFHQPPQQPPPPQEPAAPGA-------SLSPSFGSTWSTGT 115 S ++ G PP PP + +PGA P ++ TGT Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669 Query: 116 TNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTF---SPQIGLAQTQHHQQPPPPAPA 172 ++G +P P GTF SP +G P+ Sbjct: 670 PPG-----YRGTSP---------------PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709 Query: 173 PQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227 P PA PA P Q ++ PA + P + A + P + PS +S A Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764 Score = 30.8 bits (68), Expect = 4.4 Identities = 53/225 (23%), Positives = 80/225 (35%), Gaps = 26/225 (11%) Query: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67 +K + + + ++ +R + Q + E PS P E SAV + P P P Sbjct: 824 EKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPAL 883 Query: 68 PDKMQMESP--LLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWST--GTTNAVEDSF 123 + P + PG H P P +P G ++ + S + A E Sbjct: 884 RTLSEYARPHVMSPGNRNH-PFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDL 942 Query: 124 FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHH----QQPPPPAPAPQPAQPA 179 + P F+ P + P+ G P GL H QP PP P P P+ Sbjct: 943 RDRLKPG-----FEVKPSELEPLHG---VPGPGLDPFPRHGGLALQPGPPGLHPFPFHPS 994 Query: 180 QPP-QAQPPQQRRSPASPSQAPYAQRSAA--------AAYGHQPI 215 P + + PA YA+R AA AA G+ P+ Sbjct: 995 LGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPL 1039 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 56.2 bits (134), Expect = 1e-07 Identities = 99/431 (22%), Positives = 142/431 (32%), Gaps = 102/431 (23%) Query: 4 DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET---PKPEENSAVPALSPAA 60 D+ D T P + S +S+ P+ P P P+ + P A+ Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182 Query: 61 APPAPNGPDKMQMESPLLPGLS--FHQPPQQPPP----------------PQEPAAPGAS 102 P P+ +P+ P S F PP PPP P P GA+ Sbjct: 183 FEPHPS-VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241 Query: 103 LS---PSFGSTWSTGTTN-AVEDSFFQGI-------TPVNGTMLFQ-----NFPH----- 141 S P+ G TT +V S G TPV G L NFPH Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301 Query: 142 ----HVNPVFGGTFSPQ-IGLAQTQHHQQPP----------PPAPAPQPAQPAQPPQAQP 186 + P+ + SP +G H P PP P P A P + P Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-APSPHSLP 360 Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQ 246 P +PA P + PY SSS+ ++AAA++++SS+SSS + Sbjct: 361 PASSSAPAPPMRFPY--------------------SSSSSSSAAASSSSSSSSSSASPFP 400 Query: 247 SVNAAWSAPSN--PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPP 304 + A S P + P L P P P P + +S PP Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQP--------------PKYTQPSLPSQAVWSQGPPPPP 446 Query: 305 KFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPL 364 + R L + S F G P T + H + + + Sbjct: 447 PYGR---LLANSNAHPGPFPPSTGAQ----STAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 365 KGKHYPPSGPP 375 + +H+ SGPP Sbjct: 500 QQQHHGNSGPP 510 Score = 50.8 bits (120), Expect = 4e-06 Identities = 71/287 (24%), Positives = 98/287 (34%), Gaps = 39/287 (13%) Query: 13 QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQ 72 Q Q QQQQ+QQQQ Q + P P P E + P A P+ + Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS------LG 537 Query: 73 MESPLLPGLSFHQPPQQPPPPQE-------PAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125 P PG P PPP + P P S S + S+ S G+ S Q Sbjct: 538 SLRPYPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592 Query: 126 GITPVNGTMLFQNFP------HHVNPVFGGTFSPQIGLAQTQHHQQPPP---PAPAPQPA 176 G P F P ++ V S G +T PPP AP+P Sbjct: 593 G--PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPPYGKRAPSPGAY 649 Query: 177 QPAQPP---QAQPPQQRRSP------ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227 + A PP PP R SP P + + G P+ + PS ++ Sbjct: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709 Query: 228 AAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274 AA A+ S+ Q + P +P ++ P + V V Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756 Score = 40.8 bits (94), Expect = 0.004 Identities = 55/235 (23%), Positives = 76/235 (32%), Gaps = 41/235 (17%) Query: 14 PQPQQQQRQQQQ----PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69 P P Q Q P SS + + ST S S P +P PP P Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609 Query: 70 KMQMESPLLP-------GLSFHQPPQQPPPPQEPAAPGA-------SLSPSFGSTWSTGT 115 S ++ G PP PP + +PGA P ++ TGT Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669 Query: 116 TNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTF---SPQIGLAQTQHHQQPPPPAPA 172 ++G +P P GTF SP +G P+ Sbjct: 670 PPG-----YRGTSP---------------PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709 Query: 173 PQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227 P PA PA P Q ++ PA + P + A + P + PS +S A Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764 Score = 30.8 bits (68), Expect = 4.4 Identities = 53/225 (23%), Positives = 80/225 (35%), Gaps = 26/225 (11%) Query: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67 +K + + + ++ +R + Q + E PS P E SAV + P P P Sbjct: 824 EKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPAL 883 Query: 68 PDKMQMESP--LLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWST--GTTNAVEDSF 123 + P + PG H P P +P G ++ + S + A E Sbjct: 884 RTLSEYARPHVMSPGNRNH-PFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDL 942 Query: 124 FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHH----QQPPPPAPAPQPAQPA 179 + P F+ P + P+ G P GL H QP PP P P P+ Sbjct: 943 RDRLKPG-----FEVKPSELEPLHG---VPGPGLDPFPRHGGLALQPGPPGLHPFPFHPS 994 Query: 180 QPP-QAQPPQQRRSPASPSQAPYAQRSAA--------AAYGHQPI 215 P + + PA YA+R AA AA G+ P+ Sbjct: 995 LGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPL 1039 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 56.2 bits (134), Expect = 1e-07 Identities = 74/299 (24%), Positives = 96/299 (32%), Gaps = 26/299 (8%) Query: 10 SKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAP--PAPNG 67 +K Q P + Q P + + P P + P P+ + + SP P P P G Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104 Query: 68 PDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI 127 ++ Q P PG PPQ PQ P PG P S + QG Sbjct: 105 GNQPQGPPPP-PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP--QGP 161 Query: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQ--PAQ-------- 177 P G N P P G PQ Q Q PPP PQ P Q Sbjct: 162 PPQGG-----NQPQGPPPPPG---KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213 Query: 178 -PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAAS 236 P PQ PPQ P P P + G++P P A + + S Sbjct: 214 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQS 273 Query: 237 SASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKP 295 + S + P P AG +P++ G G P P P + P Sbjct: 274 ARSPPGKPQGPPQQEGNNPQGP--PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 52/176 (29%), Positives = 69/176 (39%), Gaps = 17/176 (9%) Query: 13 QPQ-PQQQQRQQQQPQPESSVS-EAPSTPLSSETPKPEENSAVPALSPAAAP--PAPNGP 68 QPQ P + Q P P+ + P P + P P+ + + + SP P P P G Sbjct: 168 QPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG 227 Query: 69 DKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSP-SFGSTWSTGTTNAVEDSFFQGI 127 ++ Q P PG PPQ PQ P PG P + G + S + QG Sbjct: 228 NQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP--QGP 284 Query: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183 G N P P GG +PQ Q QP P PQ +P++PPQ Sbjct: 285 PQQEG-----NNPQGPPPPAGG--NPQ--QPQAPPAGQPQGPPRPPQGGRPSRPPQ 331 Score = 30.8 bits (68), Expect = 4.4 Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 14/63 (22%) Query: 152 SPQIGLAQTQHHQQPPPPAPA------------PQPAQPAQPPQAQPPQ--QRRSPASPS 197 +PQ Q + Q PPP P PQ P PQ PPQ + RSP SP Sbjct: 35 NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94 Query: 198 QAP 200 P Sbjct: 95 GKP 97 >gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] Length = 1499 Score = 56.2 bits (134), Expect = 1e-07 Identities = 69/269 (25%), Positives = 94/269 (34%), Gaps = 42/269 (15%) Query: 7 MDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKP-----EENSAVPALSPAAA 61 +D + P+ ++R + + S E S P S E KP N A PA+ AA Sbjct: 132 LDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAM--AAP 189 Query: 62 PPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGAS--------LSPS-FGSTWS 112 P ++ + +PG P PPP P APG PS F ++ Sbjct: 190 QLGPGQTTQLPLSESSVPGA-----PHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFT 244 Query: 113 TGTTNAVEDSFFQGITPVNGTMLFQNFPHHV---------NPVFGGTFSPQIGLAQTQHH 163 T N ++ QG QN P P +P G Q+Q Sbjct: 245 THLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPP 304 Query: 164 QQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTS----- 218 PPPP PAP A PA PP+ PP+ +P+ A H T+ Sbjct: 305 PLPPPPPPAPGSAPPALPPEG-PPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANN 363 Query: 219 ------KPSSSSAVAAAAAAAAASSASSS 241 PSS+ A AAA + S Sbjct: 364 PLPPGGDPSSAPGPALLGEAAAPGNGQRS 392 Score = 40.8 bits (94), Expect = 0.004 Identities = 58/233 (24%), Positives = 74/233 (31%), Gaps = 50/233 (21%) Query: 3 DDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPS--TPLSSETPKPEENSAVPALSPAA 60 D +L + P+ + Q + P PE PS TP S P P P +P A Sbjct: 261 DSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPA 320 Query: 61 APPA----------------------------PNGPDKMQMESPLLPGLSFHQPPQQPPP 92 PP PN P +PL PG P P P Sbjct: 321 LPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPG---GDPSSAPGP 377 Query: 93 P--QEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150 E AAPG GS + + Q + + +L P G Sbjct: 378 ALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSG---ETEPFLKG- 433 Query: 151 FSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQ 203 P G + PPA AP P P QPP A PP + P Q+ +Q Sbjct: 434 --PPGGAG------EGGPPAQAPPP--PQQPPTA-PPSGLKKYEEPLQSMISQ 475 Score = 36.6 bits (83), Expect = 0.081 Identities = 50/207 (24%), Positives = 66/207 (31%), Gaps = 28/207 (13%) Query: 10 SKTQPQPQQQQRQQQQPQPESSVSEAPSTPL---SSETPKPEENSAVPALSPAAAPPAPN 66 S P P Q Q S + STPL + +T ++ +P PP P Sbjct: 1073 SSPDPTPSQNPLSLMMTQM-SKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQ 1131 Query: 67 G---------PDKMQM-----ESPL---LPGLS--FHQPPQQPPPPQEPAAPGASLSPSF 107 G P +M + +SP+ LPG H+PP P P L P+ Sbjct: 1132 GSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNA 1191 Query: 108 GSTWSTGTTNAV-----EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH 162 T + + DS PV + FP + G G Sbjct: 1192 QGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGL 1251 Query: 163 HQQPPPPAPAPQPAQPAQPPQAQPPQQ 189 Q P P P QPP PPQQ Sbjct: 1252 QQHYPSGMALPPEDLPNQPPGPMPPQQ 1278 Score = 33.9 bits (76), Expect = 0.52 Identities = 48/204 (23%), Positives = 72/204 (35%), Gaps = 33/204 (16%) Query: 26 PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGP----DKMQMESPLL--- 78 P P S P P + T P +NS + A + AP GP +M P L Sbjct: 1176 PSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQP 1235 Query: 79 -------------PGLSFHQPPQQPPPPQE-PAAPGASLSPSFGSTWSTGTTNAVEDSFF 124 PGL H P PP++ P P + P + D++ Sbjct: 1236 HGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQ-QHLMGKAMAGRMGDAYP 1294 Query: 125 QGITPVNGTMLFQ-NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183 G+ P ++L + P G P+ L++ ++P P QPP+ Sbjct: 1295 PGVLPGVASVLNDPELSEVIRPTPTGI--PEFDLSRIIPSEKPSSTLQY-FPKSENQPPK 1351 Query: 184 AQPP-------QQRRSPASPSQAP 200 AQPP Q + +PS+ P Sbjct: 1352 AQPPNLHLMNLQNMMAEQTPSRPP 1375 >gi|61966923 forkhead box B2 [Homo sapiens] Length = 432 Score = 56.2 bits (134), Expect = 1e-07 Identities = 43/109 (39%), Positives = 51/109 (46%), Gaps = 12/109 (11%) Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQ-- 198 HH +P P + Q PP AP P P P+QPPQ QPPQQ + P PS Sbjct: 158 HHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQ-QPPQQSQ-PQQPSHPG 215 Query: 199 --------APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239 A A +AAAA G ++ P AAAAAAAAA+S S Sbjct: 216 KMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTS 264 Score = 54.3 bits (129), Expect = 4e-07 Identities = 38/91 (41%), Positives = 44/91 (48%), Gaps = 15/91 (16%) Query: 158 AQTQHHQQPPPPAPAPQPAQP-------AQPPQA-QPPQQRRSPASPSQAPYAQRSAAAA 209 A HH PP P P P P P QPP A QPP P PSQ P Q+ + Sbjct: 154 AHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPP-----PHLPSQPP--QQPPQQS 206 Query: 210 YGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240 QP K ++AVAAAAAAAAA++ S Sbjct: 207 QPQQPSHPGKMQEAAAVAAAAAAAAAAAVGS 237 Score = 34.3 bits (77), Expect = 0.40 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 6/53 (11%) Query: 54 PALSPAAAPPAPNGPDKMQMESPLLPGLSFH---QPPQQPP---PPQEPAAPG 100 P P PP P+ + P P H QPPQQPP PQ+P+ PG Sbjct: 163 PQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPG 215 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 55.5 bits (132), Expect = 2e-07 Identities = 81/304 (26%), Positives = 111/304 (36%), Gaps = 49/304 (16%) Query: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67 + S T+P P ++R P + S LSS SA P SPA + P+ G Sbjct: 205 EHSTTEPSPAARRR----PSAGGGLQRPASRSLSS--------SATPLSSPARSGPSARG 252 Query: 68 PDK--MQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125 + P GL +PP Q PP++ AAP +L P S +T + +A Sbjct: 253 TPRAPAHPSQPKPKGLQALRPP-QVTPPRKDAAP--ALGPLSSSPLATPSPSAPPSP--- 306 Query: 126 GITPVNGTMLFQNFPH-HVNPVFGGTFSPQIGLAQTQHHQQPPPP-APAPQPAQPAQPPQ 183 + Q P P T S Q H P PP +P P A P Sbjct: 307 -----SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361 Query: 184 AQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243 A PP Q +P SP +P P+ T P + +A+A A S S Sbjct: 362 ALPPLQ--APPSPPASPPL----------SPLATPSPQAPNALAVHLLQAPFSPPPS--- 406 Query: 244 THQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAP 303 V A +S P++P A P +A + VP P P P S + P Sbjct: 407 --PPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP----PSPPASPPMSPSATPP 459 Query: 304 PKFP 307 P+ P Sbjct: 460 PQAP 463 Score = 55.5 bits (132), Expect = 2e-07 Identities = 71/243 (29%), Positives = 90/243 (37%), Gaps = 42/243 (17%) Query: 16 PQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGP---DKMQ 72 P Q P +++ S PS PLS P + AL P APP+P + Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382 Query: 73 MESPLLP-GLSFH--QPPQQPPPP---QEPAAPGAS--LSPSFGSTWSTGTTNAVEDSFF 124 SP P L+ H Q P PPP Q P +P AS +SPS Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS------------------ 424 Query: 125 QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAP----QPAQPAQ 180 P P V P SP + + T Q PPP A P +P A Sbjct: 425 -ATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481 Query: 181 PPQAQPPQQR--RSPAS-PSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237 P A PP Q PAS P QAP+ S +A+ P+ T P + +AA S Sbjct: 482 PALATPPLQALPSPPASFPGQAPF---SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 Query: 238 ASS 240 +S Sbjct: 539 PAS 541 Score = 49.3 bits (116), Expect = 1e-05 Identities = 65/246 (26%), Positives = 84/246 (34%), Gaps = 26/246 (10%) Query: 34 EAP-STPLSSETPKPEENSAVPALSPAAAPP--APNGPDKMQMESPLLPGLSFHQPPQQP 90 +AP S P S P A P +SP+A PP AP ++ P P S P Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457 Query: 91 PPPQEP---AAPGASLS---PSFGSTWSTGTTNAVED--SFFQGITPVNGTMLFQNFPHH 142 PPPQ P AAP L+ P +T A+ + F G P + + P Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 Query: 143 VNPVFGGTFSPQIGLAQTQHHQQPPPPA----------PAPQPAQPAQPPQAQPPQQRRS 192 P +P + LA P PPA P P P P+ Sbjct: 518 TPP----PQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 Query: 193 PASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAW 252 P PS++P + S GH TS P + AA+S AAW Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632 Query: 253 SAPSNP 258 S P Sbjct: 633 SRGPAP 638 Score = 44.7 bits (104), Expect = 3e-04 Identities = 72/276 (26%), Positives = 108/276 (39%), Gaps = 30/276 (10%) Query: 55 ALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPG-ASLSPSFGSTWST 113 A P +AP A GP + P G PP + P ++PG AS + G Sbjct: 68 ATIPESAPRA--GPTRTSR--PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 Query: 114 GTTNAVEDSFFQG--ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP--PPP 169 G + E++ +G + L + GT SP + + P P Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183 Query: 170 APAPQPAQPAQ-PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAA 228 AP+ +P P + P ++ S PS P A+R +A G Q +P+S S Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPS--PAARRRPSAGGGLQ-----RPASRS---L 233 Query: 229 AAAAAAASSASSSWNTHQSVNAAWSAPSNPW-GGLQAGRDPR---------RAVGVGVGV 278 +++A SS + S + + A + PS P GLQA R P+ A+G Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 Query: 279 GVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTS 314 + PSP P SP P + +PP P + TS Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 Score = 40.0 bits (92), Expect = 0.007 Identities = 57/229 (24%), Positives = 77/229 (33%), Gaps = 41/229 (17%) Query: 28 PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPG------- 80 P S + P +PL++ P+ A P L +PPA P P PG Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSG 561 Query: 81 --LSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQN 138 L+ P PPPP +P ++LS + S+ T+ E+ + G Sbjct: 562 PRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEE--------LRG------ 605 Query: 139 FPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP-- 196 + P G SP H PAP A P P P S Sbjct: 606 --YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663 Query: 197 ------SQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239 ++ P + A A P P +S AAA A A ASS S Sbjct: 664 LCTIYETEGPESATPAPGALDPGP----SPGTSGGKAAAGAGAGASSRS 708 Score = 39.7 bits (91), Expect = 0.010 Identities = 67/304 (22%), Positives = 105/304 (34%), Gaps = 44/304 (14%) Query: 26 PQPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSF 83 P+P S P T P S + E ++ P+ + P A G ++ P LS Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-----LQRPASRSLSS 235 Query: 84 HQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHV 143 P P P+A G +P+ S + Q + P T ++ + Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQ--------PKPKGLQALRPPQVTPPRKDAAPAL 287 Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQ----PAQPAQPP------------QAQPP 187 P+ + T PP P+ P P+ PA PP QA Sbjct: 288 GPLSSSPLA-------TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340 Query: 188 QQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS 247 P SP P Q A A P + + PS ++ + A + A ++ H Sbjct: 341 FLPSPPLSPLATPPPQAPPALAL---PPLQAPPSPPASPPLSPLATPSPQAPNALAVH-L 396 Query: 248 VNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFP 307 + A +S P +P +QA P + V +P + +P + S +PP P Sbjct: 397 LQAPFSPPPSP--PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454 Query: 308 RAAP 311 A P Sbjct: 455 SATP 458 Score = 37.0 bits (84), Expect = 0.062 Identities = 72/301 (23%), Positives = 105/301 (34%), Gaps = 32/301 (10%) Query: 31 SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90 S E + ++E PK SA + P P P G P P Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTEVGLPRPAP 185 Query: 91 PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150 P G S S S ST E S P G L + ++ Sbjct: 186 SARPRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 Query: 151 FSPQIGLAQTQHHQQPP--PPAPAPQPAQPAQPPQAQPPQQRRSPA--SPSQAPYAQRSA 206 SP + + P P P P+ Q +PPQ PP++ +PA S +P A S Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300 Query: 207 AAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGR 266 +A P ++ PS + + A + ++ S T Q+ ++ PS P L A Sbjct: 301 SA----PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS--FLPSPPLSPL-ATP 353 Query: 267 DPRRAVGVGVGVGVGVPSP--LNPISPL--KKPFSSNVIA----------PPKFPRAAPL 312 P+ + + PSP P+SPL P + N +A PP P AP Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413 Query: 313 T 313 + Sbjct: 414 S 414 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,659,206 Number of Sequences: 37866 Number of extensions: 2207721 Number of successful extensions: 52616 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 745 Number of HSP's successfully gapped in prelim test: 1656 Number of HSP's that attempted gapping in prelim test: 21142 Number of HSP's gapped (non-prelim): 17789 length of query: 698 length of database: 18,247,518 effective HSP length: 109 effective length of query: 589 effective length of database: 14,120,124 effective search space: 8316753036 effective search space used: 8316753036 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.