Guide to the Human Genome
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Search of human proteins with 50345881

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50345881 cytoplasmic polyadenylation element binding protein
3 [Homo sapiens]
         (698 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50345881 cytoplasmic polyadenylation element binding protein ...  1455   0.0  
gi|189027090 cytoplasmic polyadenylation element binding protein...   738   0.0  
gi|33188441 cytoplasmic polyadenylation element binding protein ...   726   0.0  
gi|33188439 cytoplasmic polyadenylation element binding protein ...   711   0.0  
gi|119395725 cytoplasmic polyadenylation element binding protein...   214   2e-55
gi|119395722 cytoplasmic polyadenylation element binding protein...   214   2e-55
gi|119395720 cytoplasmic polyadenylation element binding protein...   214   2e-55
gi|119395718 cytoplasmic polyadenylation element binding protein...   208   1e-53
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    68   3e-11
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    64   4e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    64   4e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              64   6e-10
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    60   5e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         60   5e-09
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             60   9e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       59   1e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    59   1e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    59   2e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    58   3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          57   4e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          57   4e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          57   4e-08
gi|146134388 YLP motif containing 1 [Homo sapiens]                     57   4e-08
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]              57   8e-08
gi|55750053 atrophin-1 [Homo sapiens]                                  56   1e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  56   1e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    56   1e-07
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  56   1e-07
gi|61966923 forkhead box B2 [Homo sapiens]                             56   1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   2e-07

>gi|50345881 cytoplasmic polyadenylation element binding protein 3
           [Homo sapiens]
          Length = 698

 Score = 1455 bits (3767), Expect = 0.0
 Identities = 698/698 (100%), Positives = 698/698 (100%)

Query: 1   MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60
           MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA
Sbjct: 1   MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60

Query: 61  APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120
           APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE
Sbjct: 61  APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120

Query: 121 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 180
           DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ
Sbjct: 121 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 180

Query: 181 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240
           PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS
Sbjct: 181 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240

Query: 241 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 300
           SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV
Sbjct: 241 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 300

Query: 301 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 360
           IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD
Sbjct: 301 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 360

Query: 361 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL 420
           HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL
Sbjct: 361 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQAL 420

Query: 421 SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY 480
           SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY
Sbjct: 421 SSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSY 480

Query: 481 FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD 540
           FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD
Sbjct: 481 FPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMD 540

Query: 541 GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN 600
           GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN
Sbjct: 541 GSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSN 600

Query: 601 QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ 660
           QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ
Sbjct: 601 QQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQ 660

Query: 661 YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698
           YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS
Sbjct: 661 YYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698


>gi|189027090 cytoplasmic polyadenylation element binding protein 4
           [Homo sapiens]
          Length = 729

 Score =  738 bits (1906), Expect = 0.0
 Identities = 418/726 (57%), Positives = 489/726 (67%), Gaps = 94/726 (12%)

Query: 1   MQDDLL-MDKSKTQPQPQQQ--QRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALS 57
           +QD++L  +K+K+Q Q QQ   ++QQ  P P       P T    E  K EEN    +  
Sbjct: 70  IQDEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPET----EKAKSEENQGDNSSE 125

Query: 58  PAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWS----- 112
                   NG +K+++ESP+L G  + +        Q P    AS    F S WS     
Sbjct: 126 NG------NGKEKIRIESPVLTGFDYQEATGLGTSTQ-PLTSSASSLTGF-SNWSAAIAP 177

Query: 113 TGTTNAVEDS--FFQGITPV----NGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166
           + +T   ED+  F QG  P     NG +LFQNFPHHV+P FGG+FSPQIG   +QHH   
Sbjct: 178 SSSTIINEDASFFHQGGVPAASANNGALLFQNFPHHVSPGFGGSFSPQIG-PLSQHHPHH 236

Query: 167 PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAV 226
           P            Q   +Q  QQRRSPASP   P+  R+AA  +   P + +        
Sbjct: 237 PH----------FQHHHSQHQQQRRSPASPHPPPFTHRNAA--FNQLPHLANN------- 277

Query: 227 AAAAAAAAASSASSSWNTHQSVNAAWSAPSNP-------WGGLQAGRDPRRAVGVGVGVG 279
                    +   S W+++QS +   S+  +P       WGG Q GRD RR +  G+   
Sbjct: 278 --------LNKPPSPWSSYQSPSPTPSSSWSPGGGGYGGWGGSQ-GRDHRRGLNGGI--- 325

Query: 280 VGVPSPLNPISPLKKPFSSNVIAPPKFPR-AAPLTSKSWMEDNAFRTDNGNNLLPFQDRS 338
               +PLN ISPLKK F+SN I   K+ R ++    KSWMED+  R DN   + PF DR 
Sbjct: 326 ----TPLNSISPLKKNFASNHIQLQKYARPSSAFAPKSWMEDSLNRADN---IFPFPDRP 378

Query: 339 RPYDTFNLHSLENSLMDMIRTDHEPLKGK---HYPPSGPPMSFADIMWRNHFAGRMGINF 395
           R   TF++HSLE+SL+D++R +++ +KG+    YP S      + ++      GR     
Sbjct: 379 R---TFDMHSLESSLIDIMRAENDTIKGRLNYSYPGSD-----SSLLINARTYGR----- 425

Query: 396 HHPGTDNIMALNNAFLDDSHGDQALSSGLSSPTRC---QNGERVERYSRKVFVGGLPPDI 452
              G  ++  + + FLDD  GDQ L SGL SP  C   QNGERVERYSRKVFVGGLPPDI
Sbjct: 426 -RRGQSSLFPMEDGFLDDGRGDQPLHSGLGSP-HCFSHQNGERVERYSRKVFVGGLPPDI 483

Query: 453 DEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLY 512
           DEDEITASFRRFGPL+VDWPHKAESKSYFPPKGYAFLLFQ+ESSVQALIDAC+EEDGKLY
Sbjct: 484 DEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACIEEDGKLY 543

Query: 513 LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL 572
           LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL
Sbjct: 544 LCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRL 603

Query: 573 YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLD 632
           YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQH +IDKRVEVKPYVLD
Sbjct: 604 YGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLD 663

Query: 633 DQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRH 692
           DQ+CDECQG RCGGKFAPFFCANVTCLQYYCEYCWA+IHSRAGREFHKPLVKEGGDRPRH
Sbjct: 664 DQLCDECQGARCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRH 723

Query: 693 VPFRWS 698
           + FRW+
Sbjct: 724 ISFRWN 729


>gi|33188441 cytoplasmic polyadenylation element binding protein 2
           isoform A [Homo sapiens]
          Length = 559

 Score =  726 bits (1875), Expect = 0.0
 Identities = 391/630 (62%), Positives = 435/630 (69%), Gaps = 110/630 (17%)

Query: 104 SPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPV-----------FGGTFS 152
           SP   + +  G  +++  +FF   +PV+        PH    +           FGG FS
Sbjct: 5   SPDSENGFYPGLPSSMNPAFFPSFSPVS--------PHGCTGLSVPTSGGGGGGFGGPFS 56

Query: 153 PQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP--PQQRRSPASPSQAPYAQRSAAA-- 208
                        PPPP PA    Q   PP A P  PQ RRSP SP      Q +AAA  
Sbjct: 57  ATA---------VPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFL 107

Query: 209 ----AYGH-QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263
               +Y H QP++   P                     W+ HQS  + W   S  WG + 
Sbjct: 108 QQRNSYNHHQPLLKQSP---------------------WSNHQS--SGWGTGSMSWGAMH 144

Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNA 322
            GRD RR   +G+      P  +N ISPLKKPFS NVIAPPKF R+ P LT KSW+EDN 
Sbjct: 145 -GRDHRRTGNMGI------PGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNV 197

Query: 323 FRTDNGNN-LLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPLKGKHYPPSGPPMSFADI 381
           FRTDN +N LLP QDRSR YD+ N+HSLENSL+D++R +H+PLKG+              
Sbjct: 198 FRTDNNSNTLLPLQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGR-------------- 243

Query: 382 MWRNHFAGRMGINFHHPGTDNIMALN---------NAFLDDSHGDQALSSGLSSPTRC-- 430
                      +++ HPGTDN++ LN         +  LDD H DQ     L+SPT C  
Sbjct: 244 -----------LSYPHPGTDNLLMLNGRSSLFPIDDGLLDDGHSDQV--GVLNSPT-CYS 289

Query: 431 --QNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF 488
             QNGER+ER+SRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF
Sbjct: 290 AHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAF 349

Query: 489 LLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR 548
           LLFQEESSVQALIDAC+EEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR
Sbjct: 350 LLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPR 409

Query: 549 KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI 608
           KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI
Sbjct: 410 KTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAI 469

Query: 609 SARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWA 668
           SARFVQLQH DIDKRVEVKPYVLDDQMCDECQG RCGGKFAPFFCANVTCLQYYCE+CWA
Sbjct: 470 SARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWA 529

Query: 669 SIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698
           +IHSRAGREFHKPLVKEG DRPR + FRW+
Sbjct: 530 NIHSRAGREFHKPLVKEGADRPRQIHFRWN 559



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 27/97 (27%)

Query: 26  PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMES---------- 75
           P P+S     P  P S            PA  P+ +P +P+G   + + +          
Sbjct: 4   PSPDSENGFYPGLPSSMN----------PAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGG 53

Query: 76  -------PLLPGLSFHQPPQQPPPPQEPAAPGASLSP 105
                  P  P  + + P QQPPPP  P  P +  SP
Sbjct: 54  PFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSP 90


>gi|33188439 cytoplasmic polyadenylation element binding protein 2
           isoform B [Homo sapiens]
          Length = 589

 Score =  711 bits (1834), Expect = 0.0
 Identities = 391/660 (59%), Positives = 435/660 (65%), Gaps = 140/660 (21%)

Query: 104 SPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPV-----------FGGTFS 152
           SP   + +  G  +++  +FF   +PV+        PH    +           FGG FS
Sbjct: 5   SPDSENGFYPGLPSSMNPAFFPSFSPVS--------PHGCTGLSVPTSGGGGGGFGGPFS 56

Query: 153 PQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP--PQQRRSPASPSQAPYAQRSAAA-- 208
                        PPPP PA    Q   PP A P  PQ RRSP SP      Q +AAA  
Sbjct: 57  ATA---------VPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFL 107

Query: 209 ----AYGH-QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263
               +Y H QP++   P                     W+ HQS  + W   S  WG + 
Sbjct: 108 QQRNSYNHHQPLLKQSP---------------------WSNHQS--SGWGTGSMSWGAMH 144

Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNA 322
            GRD RR   +G+      P  +N ISPLKKPFS NVIAPPKF R+ P LT KSW+EDN 
Sbjct: 145 -GRDHRRTGNMGI------PGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNV 197

Query: 323 FRTDNGNN-LLPFQ------------------------------DRSRPYDTFNLHSLEN 351
           FRTDN +N LLP Q                              DRSR YD+ N+HSLEN
Sbjct: 198 FRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLEN 257

Query: 352 SLMDMIRTDHEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALN---- 407
           SL+D++R +H+PLKG+                         +++ HPGTDN++ LN    
Sbjct: 258 SLIDIMRAEHDPLKGR-------------------------LSYPHPGTDNLLMLNGRSS 292

Query: 408 -----NAFLDDSHGDQALSSGLSSPTRC----QNGERVERYSRKVFVGGLPPDIDEDEIT 458
                +  LDD H DQ     L+SPT C    QNGER+ER+SRKVFVGGLPPDIDEDEIT
Sbjct: 293 LFPIDDGLLDDGHSDQV--GVLNSPT-CYSAHQNGERIERFSRKVFVGGLPPDIDEDEIT 349

Query: 459 ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSP 518
           ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDAC+EEDGKLYLCVSSP
Sbjct: 350 ASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSP 409

Query: 519 TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY 578
           TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY
Sbjct: 410 TIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCY 469

Query: 579 AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDE 638
           AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQH DIDKRVEVKPYVLDDQMCDE
Sbjct: 470 AGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDE 529

Query: 639 CQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 698
           CQG RCGGKFAPFFCANVTCLQYYCE+CWA+IHSRAGREFHKPLVKEG DRPR + FRW+
Sbjct: 530 CQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN 589



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 27/97 (27%)

Query: 26  PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMES---------- 75
           P P+S     P  P S            PA  P+ +P +P+G   + + +          
Sbjct: 4   PSPDSENGFYPGLPSSMN----------PAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGG 53

Query: 76  -------PLLPGLSFHQPPQQPPPPQEPAAPGASLSP 105
                  P  P  + + P QQPPPP  P  P +  SP
Sbjct: 54  PFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSP 90


>gi|119395725 cytoplasmic polyadenylation element binding protein 1
           isoform 1 [Homo sapiens]
          Length = 561

 Score =  214 bits (546), Expect = 2e-55
 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%)

Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498
           YS KVF+GG+P DI E  +  +FR FG L V+WP K       PPKGY +L+F+ E SV+
Sbjct: 309 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 368

Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552
           +L+ AC    L  DG  + Y  +SS  ++ K VQ+ PW L+DS+FV   SQ LDP +T+F
Sbjct: 369 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 428

Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612
           VG +   L A  LA I++ L+GGV YAGIDTD   KYP G+GRV F+NQ+SY+ A+SA F
Sbjct: 429 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 487

Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672
           V+++     K+V++ PY L+D +C       C  +  PFFC +  C +Y+C  CW   HS
Sbjct: 488 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 541

Query: 673 RAGREFHKPLVKEGGDR 689
             G   H PL++   +R
Sbjct: 542 MEGLRHHSPLMRNQKNR 558


>gi|119395722 cytoplasmic polyadenylation element binding protein 1
           isoform 3 [Homo sapiens]
          Length = 486

 Score =  214 bits (546), Expect = 2e-55
 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%)

Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498
           YS KVF+GG+P DI E  +  +FR FG L V+WP K       PPKGY +L+F+ E SV+
Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 293

Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552
           +L+ AC    L  DG  + Y  +SS  ++ K VQ+ PW L+DS+FV   SQ LDP +T+F
Sbjct: 294 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 353

Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612
           VG +   L A  LA I++ L+GGV YAGIDTD   KYP G+GRV F+NQ+SY+ A+SA F
Sbjct: 354 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 412

Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672
           V+++     K+V++ PY L+D +C       C  +  PFFC +  C +Y+C  CW   HS
Sbjct: 413 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 466

Query: 673 RAGREFHKPLVKEGGDR 689
             G   H PL++   +R
Sbjct: 467 MEGLRHHSPLMRNQKNR 483


>gi|119395720 cytoplasmic polyadenylation element binding protein 1
           isoform 3 [Homo sapiens]
          Length = 486

 Score =  214 bits (546), Expect = 2e-55
 Identities = 115/257 (44%), Positives = 159/257 (61%), Gaps = 13/257 (5%)

Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQ 498
           YS KVF+GG+P DI E  +  +FR FG L V+WP K       PPKGY +L+F+ E SV+
Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVR 293

Query: 499 ALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIF 552
           +L+ AC    L  DG  + Y  +SS  ++ K VQ+ PW L+DS+FV   SQ LDP +T+F
Sbjct: 294 SLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVF 353

Query: 553 VGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARF 612
           VG +   L A  LA I++ L+GGV YAGIDTD   KYP G+GRV F+NQ+SY+ A+SA F
Sbjct: 354 VGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKAVSAAF 412

Query: 613 VQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHS 672
           V+++     K+V++ PY L+D +C       C  +  PFFC +  C +Y+C  CW   HS
Sbjct: 413 VEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCWHWRHS 466

Query: 673 RAGREFHKPLVKEGGDR 689
             G   H PL++   +R
Sbjct: 467 MEGLRHHSPLMRNQKNR 483


>gi|119395718 cytoplasmic polyadenylation element binding protein 1
           isoform 2 [Homo sapiens]
          Length = 491

 Score =  208 bits (530), Expect = 1e-53
 Identities = 115/262 (43%), Positives = 159/262 (60%), Gaps = 18/262 (6%)

Query: 439 YSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKG-----YAFLLFQE 493
           YS KVF+GG+P DI E  +  +FR FG L V+WP K       PPKG     Y +L+F+ 
Sbjct: 234 YSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFEL 293

Query: 494 ESSVQALIDAC----LEEDG--KLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDP 547
           E SV++L+ AC    L  DG  + Y  +SS  ++ K VQ+ PW L+DS+FV   SQ LDP
Sbjct: 294 EKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDP 353

Query: 548 RKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAA 607
            +T+FVG +   L A  LA I++ L+GGV YAGIDTD   KYP G+GRV F+NQ+SY+ A
Sbjct: 354 SRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKH-KYPIGSGRVTFNNQRSYLKA 412

Query: 608 ISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCW 667
           +SA FV+++     K+V++ PY L+D +C       C  +  PFFC +  C +Y+C  CW
Sbjct: 413 VSAAFVEIKTTKFTKKVQIDPY-LEDSLCH-----ICSSQPGPFFCRDQVCFKYFCRSCW 466

Query: 668 ASIHSRAGREFHKPLVKEGGDR 689
              HS  G   H PL++   +R
Sbjct: 467 HWRHSMEGLRHHSPLMRNQKNR 488


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 96/318 (30%), Positives = 120/318 (37%), Gaps = 41/318 (12%)

Query: 11  KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDK 70
           +T   P      +  P P     +AP +PL+  TP PE  S++ A  P  APPA   P  
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLT--TPPPETPSSI-ATPPPQAPPALASPPL 603

Query: 71  MQMESPLLPGLSFHQPPQQPP-----PPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125
             + SP L  L+   PPQ PP     P Q P +P AS   S  +T S    NA+     Q
Sbjct: 604 QGLPSPPLSPLAT-PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662

Query: 126 GITPVNGTMLFQNFPHH-VNPVFGGTFSPQIGLAQTQHHQQPP----PPAPAPQ--PAQP 178
                     F   P   V   F    SP +  + T   Q PP    PP   P   PA P
Sbjct: 663 AP--------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714

Query: 179 AQPPQAQPPQQRRSP--ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAAS 236
              P A PP Q   P  A P Q P    S  A+    P  T  P     +AA       S
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVP---PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771

Query: 237 SASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296
             +S   +  +     + P+     LQA   P  +     G     PS   P+SPL  P 
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF---PGQAPFSPSASLPMSPLATP- 827

Query: 297 SSNVIAPPKFP--RAAPL 312
                 PP+ P   AAPL
Sbjct: 828 ------PPQAPPVLAAPL 839



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 73/296 (24%), Positives = 114/296 (38%), Gaps = 30/296 (10%)

Query: 8   DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67
           + S T+P P  ++R    P     +    S  LSS        SA P  SPA + P+  G
Sbjct: 214 EHSTTEPSPAARRR----PSAGGGLQRPASRSLSS--------SATPLSSPARSGPSARG 261

Query: 68  PDKMQME--SPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWS-TGTTNAVEDSFF 124
             +       P   GL   +PPQ  PP ++ A     LS S  +T S +GT         
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321

Query: 125 QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ--PP 182
              TP+  T+     P    P+     +P    A       P PPA  P  A P+   PP
Sbjct: 322 NAATPLPATL--PPSPPLATPL---PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 183 QAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSW 242
              PP  +  P  P Q P++  S +      P+  S   +++++ +    A  S  + S 
Sbjct: 377 MQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS- 433

Query: 243 NTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNP-ISPLKKPFS 297
              +   A+ ++PS P         P     + +     + + L+P +SPL  P +
Sbjct: 434 --PRQTQASLTSPSRP--ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 59/246 (23%), Positives = 81/246 (32%), Gaps = 21/246 (8%)

Query: 28  PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPP 87
           P S  +  P +P ++  P+     A P L    +PPA           P +P L    P 
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766

Query: 88  QQPPPPQE--PAAPGASLSPSFGSTWSTGTTNAVED--SFFQGITPVNGTMLFQNFPHHV 143
           Q PP P    P +P A   P      +T    A+    + F G  P + +      P   
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826

Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRS----------- 192
            P      +P +  A     Q PP P  +P    P +PP   P                 
Sbjct: 827 PP----PQAPPVLAAPLL--QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 880

Query: 193 PASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAW 252
           P  PS++P +  S     GH    TS P       +     AA+S            AAW
Sbjct: 881 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940

Query: 253 SAPSNP 258
           S    P
Sbjct: 941 SRGPAP 946



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 83/333 (24%), Positives = 114/333 (34%), Gaps = 80/333 (24%)

Query: 16  PQQQQRQQQQP-QPESSVSEAP--STPLSSETPKPEENSAVPALSPAAAPPAPN---GPD 69
           P+Q Q     P +P S+  ++P    PLS     P + S  PA+SP ++P   +      
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 70  KMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITP 129
            +   SP  P  S   PP +    Q   AP +  +P    T                   
Sbjct: 494 SLASHSPQAPLSSLIMPPLET---QSSLAPPSLQTPPASLT------------------- 531

Query: 130 VNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA---------- 179
              T   +N P    P      +P      T H + PP PAP P  A P+          
Sbjct: 532 ---TPPLENLPSLAPPPLQTASAP----LTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584

Query: 180 -----QPPQAQP----------PQQRRSPAS--PSQAP--------YAQRSAAAAYGHQP 214
                 PPQA P          P    SP +  P QAP         A  S  A+    P
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644

Query: 215 IMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274
           + T  P + +A+A     A  S   S       V A +S P++P     A   P +A   
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPS-----PPVQAPFSPPASPPVSPSA-TPPSQAPPS 698

Query: 275 GVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFP 307
                + VP    P  P   P S +   PP+ P
Sbjct: 699 LAAPPLQVP----PSPPASPPMSPSATPPPQAP 727



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 65/262 (24%), Positives = 100/262 (38%), Gaps = 30/262 (11%)

Query: 51  SAVPALSPAAAPPAPNGPDKMQMES-PLLPGLSFHQPPQQPPPPQEPAAPG-ASLSPSFG 108
           + +P  +P A P    G       S P   G     PP +   P   ++PG AS +   G
Sbjct: 68  ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127

Query: 109 STWSTGTTNAVEDSFFQG--ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166
                G   + E++  +G        + L        +    GT SP +         + 
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 167 --PPPAPAPQPAQPAQ-PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSS 223
             P PAP+ +P  P + P ++       S   PS  P A+R  +A  G Q     +P+S 
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS--PAARRRPSAGGGLQ-----RPASR 240

Query: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPW-GGLQAGRDPRRAVGVGVGVGVGV 282
           S    +++A   SS + S  + +    A + PS P   GLQA R P+            V
Sbjct: 241 S---LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ------------V 285

Query: 283 PSPLNPISPLKKPFSSNVIAPP 304
             P    +P   P SS+ +A P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATP 307



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 57/229 (24%), Positives = 77/229 (33%), Gaps = 41/229 (17%)

Query: 28   PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPG------- 80
            P S  +  P +PL++  P+     A P L    +PPA   P       P  PG       
Sbjct: 812  PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSG 869

Query: 81   --LSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQN 138
              L+    P  PPPP    +P ++LS    +  S+  T+  E+        + G      
Sbjct: 870  PRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEE--------LRG------ 913

Query: 139  FPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP-- 196
              +   P  G   SP         H       PAP  A    P    P      P S   
Sbjct: 914  --YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971

Query: 197  ------SQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239
                  ++ P +   A  A    P     P +S   AAA A A ASS S
Sbjct: 972  LCTIYETEGPESATPAPGALDPGP----SPGTSGGKAAAGAGAGASSRS 1016



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 77/361 (21%), Positives = 116/361 (32%), Gaps = 43/361 (11%)

Query: 31  SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90
           S  E  +   ++E PK    SA      +   P P  P           G     P   P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTEVGLPRPAP 194

Query: 91  PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150
                P   G   S S  S  ST      E S      P  G  L +     ++      
Sbjct: 195 SARPRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 151 FSPQIGLAQTQHHQQPP--PPAPAPQPAQPAQPPQAQPPQQRRSPA--SPSQAPYAQRSA 206
            SP       +   + P  P  P P+  Q  +PPQ  PP++  +PA    S +P A  S 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 207 AAAYGH---QPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQ 263
           +         P   + P  ++   +   A     A  S +   S+    S P+ P     
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP----- 364

Query: 264 AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF---SSNVIAPPKFPRAAPLTSKSWMED 320
               P +A        +  P  L  I P++ P    S ++ APP     +PL   S    
Sbjct: 365 ----PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP-----SPLALSSLQAT 415

Query: 321 NAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIR-----TDHEPLKGKHYPPSGPP 375
            +  +       P    +  + T +    + SL    R      D  PL+     P+ PP
Sbjct: 416 TSLGS-------PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468

Query: 376 M 376
           +
Sbjct: 469 L 469


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 70/309 (22%), Positives = 107/309 (34%), Gaps = 29/309 (9%)

Query: 25  QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84
           +P P   +   P  P      +P  +  +P + P    P P GP  +Q    + P +S  
Sbjct: 48  RPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM 107

Query: 85  QPP---QQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF------QGITPVNGTML 135
            PP     PP      APG    P     W    T   +  ++         T  +G  +
Sbjct: 108 PPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKV 167

Query: 136 FQNFPHHVNPVFGGTFSPQI-----------GLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184
            Q     + P+       Q              AQ Q   Q    A A   AQ     QA
Sbjct: 168 IQQ--SELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 225

Query: 185 QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244
           Q   Q ++ A        Q    A    Q +  S P++SS   A + + ++S+ SS+ +T
Sbjct: 226 QAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTST 285

Query: 245 HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGV-GVGVGVPSP-LNPISPLKKPFSSNVIA 302
             +  +     S P       + P  AV V    V V  P+P   P+  + +P    +  
Sbjct: 286 TTTATSVAQTVSTP---TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL-- 340

Query: 303 PPKFPRAAP 311
           PP  P + P
Sbjct: 341 PPAVPHSVP 349



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 60/254 (23%), Positives = 96/254 (37%), Gaps = 17/254 (6%)

Query: 5   LLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPA 64
           +L  +++ Q Q Q Q + Q Q Q ++  ++A +   +    + +  +   A + A A   
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 234

Query: 65  PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124
                + Q+++ +   +         P    PA P  S S S  +  ST +T     S  
Sbjct: 235 AQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA-PAVSTSTSSSTPSSTTSTTTTATSVA 293

Query: 125 QGI-TPVNGTMLFQNFPHHVNPVFG-GTFSPQIGLAQT--QHHQQPPPPA-----PAPQP 175
           Q + TP        +      P     T +P     QT  Q H Q  PPA     P P  
Sbjct: 294 QTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT 353

Query: 176 AQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAA 235
           A PA PP   PP +   P  P   P          G  P +        A+AA+ A  A 
Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLP------GVLPGMAPPIVPMIHPQVAIAASPATLAG 407

Query: 236 SSASSSWNTHQSVN 249
           ++A S W  +++ +
Sbjct: 408 ATAVSEWTEYKTAD 421


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 70/309 (22%), Positives = 107/309 (34%), Gaps = 29/309 (9%)

Query: 25  QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84
           +P P   +   P  P      +P  +  +P + P    P P GP  +Q    + P +S  
Sbjct: 48  RPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSM 107

Query: 85  QPP---QQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF------QGITPVNGTML 135
            PP     PP      APG    P     W    T   +  ++         T  +G  +
Sbjct: 108 PPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKV 167

Query: 136 FQNFPHHVNPVFGGTFSPQI-----------GLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184
            Q     + P+       Q              AQ Q   Q    A A   AQ     QA
Sbjct: 168 IQQ--SELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 225

Query: 185 QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244
           Q   Q ++ A        Q    A    Q +  S P++SS   A + + ++S+ SS+ +T
Sbjct: 226 QAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTST 285

Query: 245 HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGV-GVGVGVPSP-LNPISPLKKPFSSNVIA 302
             +  +     S P       + P  AV V    V V  P+P   P+  + +P    +  
Sbjct: 286 TTTATSVAQTVSTP---TTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL-- 340

Query: 303 PPKFPRAAP 311
           PP  P + P
Sbjct: 341 PPAVPHSVP 349



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 63/269 (23%), Positives = 99/269 (36%), Gaps = 26/269 (9%)

Query: 5   LLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPA 64
           +L  +++ Q Q Q Q + Q Q Q ++  ++A +   +    + +  +   A + A A   
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 234

Query: 65  PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124
                + Q+++ +   +         P    PA P  S S S  +  ST +T     S  
Sbjct: 235 AQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA-PAVSTSTSSSTPSSTTSTTTTATSVA 293

Query: 125 QGI-TPVNGTMLFQNFPHHVNPVFG-GTFSPQIGLAQT--QHHQQPPPPA-----PAPQP 175
           Q + TP        +      P     T +P     QT  Q H Q  PPA     P P  
Sbjct: 294 QTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT 353

Query: 176 AQPAQPPQAQPPQQRRSPASP-----------SQAPYAQRSAAAAYGHQPIM----TSKP 220
           A PA PP   PP +   P  P              PY +  A    G  P M        
Sbjct: 354 AIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMI 413

Query: 221 SSSSAVAAAAAAAAASSASSSWNTHQSVN 249
               A+AA+ A  A ++A S W  +++ +
Sbjct: 414 HPQVAIAASPATLAGATAVSEWTEYKTAD 442


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 71/257 (27%), Positives = 99/257 (38%), Gaps = 38/257 (14%)

Query: 14  PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDK--- 70
           P+P+++Q+ Q    P +  SE      ++  P    NS VP LSP  +   P  P++   
Sbjct: 523 PKPERKQQPQLPRPPTTGGSEGAG---AAPCPPNPANSWVPGLSPGGSRRPPRSPERTLS 579

Query: 71  ------MQMESPLLPGLSFHQPP-----QQPPPPQEPA---APGASLSPSFGSTWSTGTT 116
                  Q  +P LP      PP      QPP P+      +PGAS+S S  S  S+ + 
Sbjct: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639

Query: 117 NAVED-SFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQP 175
            A  D S  Q +TP+    +    PH   P     FSP     ++ +   P   APA  P
Sbjct: 640 PAPSDRSGPQILTPLGDRFVIP--PH---PKVPAPFSPPPSKPRSPNPAAPALAAPAVVP 694

Query: 176 -------AQPAQPPQAQ---PPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSA 225
                  A P  PP  Q    P Q     S  Q+P    S   +Y   P  T KP     
Sbjct: 695 GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSP--PPSPPPSYHPPPPPTKKPEVVVE 752

Query: 226 VAAAAAAAAASSASSSW 242
             +A+  A       +W
Sbjct: 753 APSASETAEEPLQDPNW 769



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 80/360 (22%), Positives = 125/360 (34%), Gaps = 43/360 (11%)

Query: 23   QQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLS 82
            Q  P P+++++    +P+ S+   P   S  P+  P   PP P    ++ +E+P     +
Sbjct: 705  QSPPTPQTTLTPLQESPVISKDQSPPP-SPPPSYHP---PPPPTKKPEVVVEAPSASETA 760

Query: 83   FHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFP 140
              +P Q P  PPP  PA     LS +             E++FF   +P          P
Sbjct: 761  -EEPLQDPNWPPPPPPAPEEQDLSMA--------DFPPPEEAFFSVASPEPAGP--SGSP 809

Query: 141  HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200
              V+     + S      Q      PPP  PAP PA  A    A+ PQ+     S    P
Sbjct: 810  ELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP 869

Query: 201  YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWG 260
              +   A       +   +  S  A   A   A   SA       ++++   S    P  
Sbjct: 870  PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQK-PLRRALSGRASPVPAPSS 928

Query: 261  GLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKSWMED 320
            GL A     +A  +    G+    P  P                  P A P   +S    
Sbjct: 929  GLHAA-VRLKACSLAASEGLSSAQPNGP------------------PEAEPRPPQSPAST 969

Query: 321  NAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHE---PLKGKHYPPSGPPMS 377
             +F    G+  L  +   RP        L+ +L+  +R+  E   P   K  P + PP++
Sbjct: 970  ASFIFSKGSRKLQLE---RPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVA 1026



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 81/329 (24%), Positives = 111/329 (33%), Gaps = 68/329 (20%)

Query: 10   SKTQPQPQQQQRQQQQPQP---ESSVSEAPSTP-----LSSETPKPEENSAVPAL--SPA 59
            S+T  +P Q       P P   E  +S A   P      S  +P+P   S  P L  SPA
Sbjct: 757  SETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPA 816

Query: 60   AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPG--ASLSPSFGSTWSTGTTN 117
            A+  +      +Q++ P  P      PP  P P    +APG  A L        S G   
Sbjct: 817  ASSSSATA---LQIQPPGSPD----PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP 869

Query: 118  AVEDSFFQGITPVNGTML---FQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAP- 173
              ED     +TP    M+       P        G  +PQ  L +    +  P PAP+  
Sbjct: 870  PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSG 929

Query: 174  ------------------QPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI 215
                                AQP  PP+A+P         P Q+P +  S   + G + +
Sbjct: 930  LHAAVRLKACSLAASEGLSSAQPNGPPEAEP--------RPPQSPASTASFIFSKGSRKL 981

Query: 216  MTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVG 275
               +P S    A       A   S S             P  P       + P+    V 
Sbjct: 982  QLERPVSPETQADLQRNLVAELRSISEQR---------PPQAP------KKSPKAPPPVA 1026

Query: 276  VGVGVGVPSPLNPISPLKKPFSSNVIAPP 304
                VGVP P +P  P  +P +    APP
Sbjct: 1027 RKPSVGVPPPASPSYPRAEPLT----APP 1051


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 94/358 (26%), Positives = 118/358 (32%), Gaps = 94/358 (26%)

Query: 161 QHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP---SQAPYAQRSAAAAYGHQPIMT 217
           Q  QQPPP  P PQ   P QPP    P Q++ P  P   S  P   +    A G   + +
Sbjct: 67  QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG---VGS 123

Query: 218 SKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSA------PSNPWGGL-----QAGR 266
           + P+SSSA  A    + A   S    T     A  SA      P+ P  G+     QAG 
Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG 183

Query: 267 DPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKSWMEDNAFRTD 326
            P     V  G G G      P  P        +   PK P   P             T 
Sbjct: 184 PPPPPAAV-PGPGPGPKQGPGPGGPK----GGKMPGGPK-PGGGP----------GLSTP 227

Query: 327 NGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPLKGKHY---PPSGPPMSFADIMW 383
            G+   P +    P                 R  H P   +H+   PP GP         
Sbjct: 228 GGHPKPPHRGGGEPRGG--------------RQHHPPYHQQHHQGPPPGGP--------- 264

Query: 384 RNHFAGRMGINFHHPGTDNIMALNNAFLDDSHGDQALSSGLSSPTRCQNGERVERYSRKV 443
                GR                +   + DS G +A  S L  P     GE+      ++
Sbjct: 265 ----GGR----------------SEEKISDSEGFKANLSLLRRP-----GEKTYTQRCRL 299

Query: 444 FVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALI 501
           FVG LP DI EDE    F ++G          E    F  KG  F   + ES   A I
Sbjct: 300 FVGNLPADITEDEFKRLFAKYG----------EPGEVFINKGKGFGFIKLESRALAEI 347



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 20/177 (11%)

Query: 14  PQPQQQQRQQQQPQPESS----VSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69
           P PQ  Q+QQ  P P+ S    V++ P       +  P  +SA PA  P +  P  +GP 
Sbjct: 89  PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148

Query: 70  KMQMESPLLPGLSFHQPPQQPP-------PPQ---EPAAPGASLSPSFGSTWSTGTTNAV 119
                 P +       PP  PP       PPQ    P  P A   P  G     G     
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208

Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLA-----QTQHHQQPPPPAP 171
                 G  P  G  L     H   P  GG   P+ G         QHHQ PPP  P
Sbjct: 209 GGKMPGGPKPGGGPGLSTPGGHPKPPHRGGG-EPRGGRQHHPPYHQQHHQGPPPGGP 264



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 47/193 (24%), Positives = 60/193 (31%), Gaps = 20/193 (10%)

Query: 14  PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM 73
           P P     Q + P         P  P+    P  ++    P   P   PP    P   Q 
Sbjct: 34  PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93

Query: 74  ESPLLPGLSFHQPPQQPPPPQEPAAP----GASLSPSFGSTWSTGTTNAVEDSFFQGITP 129
                     HQ  Q PPPPQ+ + P    G   +P  GS     ++         G  P
Sbjct: 94  ----------HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143

Query: 130 VNGTMLFQNFPHHVNPVFGGT---FSPQIGLAQTQHHQQPPPPAPAPQPAQ---PAQPPQ 183
            +G       P  V     G      P  G+  T      PPP PA  P     P Q P 
Sbjct: 144 GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203

Query: 184 AQPPQQRRSPASP 196
              P+  + P  P
Sbjct: 204 PGGPKGGKMPGGP 216



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 43/157 (27%), Positives = 50/157 (31%), Gaps = 22/157 (14%)

Query: 62  PPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPA--APGASLSPSFGSTWSTGTTNAV 119
           PP P  P   Q +          QPP Q PPPQ+P    P     P           ++ 
Sbjct: 58  PPIPPPPPHQQQQ----------QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107

Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179
           +    QG  P  G            P    T     G          P P P P PA  +
Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG--------SGPGPTPTPPPAVTS 159

Query: 180 QPPQAQPPQQRRS--PASPSQAPYAQRSAAAAYGHQP 214
            PP A PP    S  P +P QA       AA  G  P
Sbjct: 160 APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 50/190 (26%), Positives = 72/190 (37%), Gaps = 13/190 (6%)

Query: 16  PQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAP---NGPDKMQ 72
           P+++ +  + P P+    E    PL    P P+    + A    A PP P       K+Q
Sbjct: 341 PKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQ 400

Query: 73  MESPLLPGLSFHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPV 130
           +  P  P    HQPP  P  PPP  P++    +S +  S++ +G       S  +   P 
Sbjct: 401 IPPPAHPA-PVHQPPPLPHRPPPPPPSSYMTGMSTT--SSYMSGEGYQSLQSMMKTEGPS 457

Query: 131 NGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQR 190
            G +     P    P     + P +          PPPPA  P PA P   P   PP   
Sbjct: 458 YGAL-----PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPT 512

Query: 191 RSPASPSQAP 200
            +P  P   P
Sbjct: 513 YNPNFPPPPP 522



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 58/232 (25%), Positives = 79/232 (34%), Gaps = 51/232 (21%)

Query: 10  SKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSP-----AAAPPA 64
           S++    Q QQ+  QQP  +   ++ P  P S +   P +      +SP     AA PP 
Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKP-SPQPSSPRQVKRAVVVSPKEENKAAEPPP 352

Query: 65  PNGPDKMQMESPLLPGLSFHQPPQQPPP------PQEPAAPGASLS-------------- 104
           P  P K++   P LP    H PP + PP        EP  P  +                
Sbjct: 353 PKIP-KIETTHPPLP--PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409

Query: 105 ------------PSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGG--- 149
                       P   S++ TG +     S+  G     G    Q+      P +G    
Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTT--SSYMSG----EGYQSLQSMMKTEGPSYGALPP 463

Query: 150 TFSPQIGLAQTQHHQQP-PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200
            + P   L    H   P PPP P P P     PP   PP     P  P+  P
Sbjct: 464 AYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP 515



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 58/261 (22%), Positives = 81/261 (31%), Gaps = 31/261 (11%)

Query: 47  PEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS 106
           P +    P+L P    P        Q   P  P     + PQQP   Q+PA      SP 
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQ---QKDPQQPAQQQQPAQQPKKPSPQ 326

Query: 107 FGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP 166
             S         V        +P       +  P            P+I   +T H   P
Sbjct: 327 PSSPRQVKRAVVV--------SPKEENKAAEPPP------------PKIPKIETTHPPLP 366

Query: 167 PP-PAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQ--RSAAAAYGHQPIMTSKPSSS 223
           P  P P  +P   A   +A+PP     P   +  P  Q    A  A  HQP         
Sbjct: 367 PAHPPPDRKPPLAAALGEAEPP----GPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP 422

Query: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVP 283
              ++     + +S+  S   +QS+ +        +G L     P   +     V    P
Sbjct: 423 PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNP 482

Query: 284 SPLNPISPLKKPFSSNVIAPP 304
            P  P+ P    F    I PP
Sbjct: 483 PP-PPVPPPPASFPPPAIPPP 502



 Score = 33.9 bits (76), Expect = 0.52
 Identities = 46/183 (25%), Positives = 64/183 (34%), Gaps = 34/183 (18%)

Query: 156 GLAQTQHH-----QQPP-----PPAPAPQPAQ------PAQPPQAQP--PQQRRSPASPS 197
           G  Q  HH     QQPP     P  P  Q +Q      P+QP Q  P  P Q++ PA   
Sbjct: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320

Query: 198 QAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSN 257
           + P  Q S+        +++ K  +       AA            TH  +  A   P  
Sbjct: 321 KKPSPQPSSPRQVKRAVVVSPKEENK------AAEPPPPKIPKIETTHPPLPPAHPPPDR 374

Query: 258 --PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSK 315
             P        +P   V       V +P P +P +P+ +P       PP   R  P    
Sbjct: 375 KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHP-APVHQP-------PPLPHRPPPPPPS 426

Query: 316 SWM 318
           S+M
Sbjct: 427 SYM 429



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 7/90 (7%)

Query: 26  PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSF-- 83
           P P      A   P +   P P      P  +P   PP P  P    +     PGL    
Sbjct: 483 PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP 542

Query: 84  --HQPPQQPP---PPQEPAAPGASLSPSFG 108
             + PP  PP   PP  P  P   + P  G
Sbjct: 543 ASYPPPAVPPGGQPPVPPPIPPPGMPPVGG 572


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 79/291 (27%), Positives = 110/291 (37%), Gaps = 51/291 (17%)

Query: 31   SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90
            S  E P++P ++  P PEE +     SPAAA P P  P       P         PP++P
Sbjct: 995  STPEEPASPAAA-VPTPEEPT-----SPAAAVPTPEEPTSPAAAVP---------PPEEP 1039

Query: 91   -------PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI---TPVNGTMLFQNFP 140
                   P P+EP +P A++      T         E+         TP   T      P
Sbjct: 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1099

Query: 141  HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPA-PQPAQPAQPPQAQP-PQQRRSPASPSQ 198
                P      SP    A     ++P  PA A P P +PA P  A P P++   PA    
Sbjct: 1100 TPEEPT-----SPA---AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151

Query: 199  APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258
             P    SAA A     + T + S+S A A    A +AS A+      +  + A S P+  
Sbjct: 1152 TPEESASAAVA-----VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206

Query: 259  --WGGLQAGRDPRRAVGVG---VGVGVGVPSPLNPISP------LKKPFSS 298
                 L+    P  +V        +   V +P  P SP      L++P SS
Sbjct: 1207 AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 69/285 (24%), Positives = 98/285 (34%), Gaps = 32/285 (11%)

Query: 26   PQPESSVSEAPSTPLSSETPKPEENSAVPA----LSPAAAPPAPNGPDKMQMESPLLPGL 81
            P PE   S A + P   E   P   +AVP      SPAAA P P        E P  P  
Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTP--------EEPASPAA 1122

Query: 82   SFHQP--PQQP----PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI---TPVNG 132
            +   P  P  P    P P+EPA P  ++     S  +       E+S        TP   
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182

Query: 133  TMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQA-QPPQQRR 191
                        P       P          +   P A  P   +PA    A   P++  
Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242

Query: 192  SPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAA 251
            SPA+         S+AAA     ++T +  SS A +       AS A++  N  +  + A
Sbjct: 1243 SPAAAVPTLEEPTSSAAA-----VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297

Query: 252  WSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296
             + P+     + A   P   V     +      P+  +SP+  PF
Sbjct: 1298 AAVPTPEVAAIPAASVPTPEV---PAIPAAAVPPMEEVSPIGVPF 1339


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 63/243 (25%), Positives = 89/243 (36%), Gaps = 25/243 (10%)

Query: 15  QPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQME 74
           Q QQQQ+QQQQ Q ++  ++ P      + P+P  + A+P           + P     +
Sbjct: 248 QQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQ 307

Query: 75  SPLLPGLSFHQPPQ---QPPPPQEPAAPGASLSPS----FGSTWSTGTTNAVEDSFFQGI 127
            P+        PPQ   QP   Q  A PG  L       F           V+    Q  
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367

Query: 128 TPVNGTMLFQNFPHHVN------PVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP 181
           T V      Q     V       P+     SP  G         PPPP P+PQP QP+  
Sbjct: 368 TAVQTAQAAQMVAPGVQVSQSSLPMLS---SPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424

Query: 182 PQA--------QPPQQRRSPA-SPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAA 232
           P +         P     SP+  PSQ+P   R+        P   + P + S+V + A +
Sbjct: 425 PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484

Query: 233 AAA 235
           + A
Sbjct: 485 SQA 487



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 37/136 (27%), Positives = 49/136 (36%), Gaps = 22/136 (16%)

Query: 5   LLMDKSKTQPQPQQQQRQQQQPQ------PESSVSEAPSTPLSSETPKPEENSAVPALSP 58
           +++ +   QPQ QQQQ   Q  Q      P   VS++    LSS +P  +  +      P
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411

Query: 59  AAAPPAPNGPDKM---QMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGT 115
               P P  P       + S   P  S   P   P P Q P     + +P   S  S G 
Sbjct: 412 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV---TARTPQNFSVPSPGP 468

Query: 116 TNAVEDSFFQGITPVN 131
            N          TPVN
Sbjct: 469 LN----------TPVN 474


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 76/318 (23%), Positives = 108/318 (33%), Gaps = 26/318 (8%)

Query: 11   KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPA-----LSPAAAPPAP 65
            K  P P        +  P +   +   TP ++  P P+   A P+       PAA PP+P
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 66   NGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125
             G        P  P       P    PP    +P A+  P   ST    T  + + S   
Sbjct: 997  KG-------GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS--P 1047

Query: 126  GITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPP--APA-PQPAQPAQPP 182
              TP+             +P  GG  +P +  A T     PP P   PA P P     PP
Sbjct: 1048 AATPLPKGAPTTPAATLPSPK-GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106

Query: 183  QAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSW 242
             A PP  +   A+P         AA     +  + + P   +    AA   +     ++ 
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166

Query: 243  NTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV------GVGVPSPLN-PISPLKKP 295
                +     + P +P GGL A   P+ A             G+  PSP   P +P   P
Sbjct: 1167 PPKGAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225

Query: 296  FSSNVIAPPKFPRAAPLT 313
             S         P+ AP T
Sbjct: 1226 PSPKGGLATPSPKGAPTT 1243



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 82/325 (25%), Positives = 115/325 (35%), Gaps = 46/325 (14%)

Query: 23   QQQPQPESSVSEAPSTPLS--SETPKPEENSAVP-------------ALSPAAAPPAPNG 67
            Q +  P    S  P TP+   S    P E S +P             A + +  PP+P G
Sbjct: 804  QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863

Query: 68   PDKMQMESPLLP-GLSFHQPPQQPP---------PPQEPAAPGASLSPSFGSTWSTGTTN 117
                   +PL P G++   PP++ P         P + PA P    +P+   T S+    
Sbjct: 864  APTPSAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT-SSSPKK 920

Query: 118  AVEDSFFQGITPVNGTMLFQNFPHHVNPVF--GGTFSPQIGLAQTQHHQQPPPP--APA- 172
            A      +GI P + +      P    P    GG  +P    A T     PP P   PA 
Sbjct: 921  ARATPAPKGI-PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 173  PQPAQPAQPPQAQPPQQRRSPASPSQ--APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230
            P P     PP A PP  +  PA+PS   AP        +    P  T  P  +S   AA 
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 231  AAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPIS 290
              +   S +++            AP+ P   L +   P+         G   P    P S
Sbjct: 1040 PPSPKGSPAAT-------PLPKGAPTTPAATLPS---PKGGPATPSLKGAPTPPAATPPS 1089

Query: 291  PLKKPFSSNVIAPPKFPRAAPLTSK 315
            P   P + +    P  P A P + K
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPK 1114



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 83/310 (26%), Positives = 110/310 (35%), Gaps = 41/310 (13%)

Query: 26   PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQ 85
            P P+++ +   +  L+ E PK   +   P+L PA  PP     D +   S L P  S   
Sbjct: 712  PSPQNTCAPLATLVLAPEIPKSVPS---PSLPPAGTPPGTKKVDGISHTSALAPVAS--- 765

Query: 86   PPQQPPPPQEPAAPGASL---------SPS-FGSTWSTGTTNAVEDSFFQG-ITPVNGTM 134
             P++ P     A+  AS          SPS  G + S  T          G  TP+    
Sbjct: 766  SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG--- 822

Query: 135  LFQNFPHHVNPVFGGTFSPQIGLA--------QTQHHQQPPPP--APAPQPAQPAQPPQA 184
               N    V+PV   +F P+  L+         T H   PP P  AP P    P  P   
Sbjct: 823  ---NLSSPVSPV-EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878

Query: 185  QPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNT 244
              P +     S    P+ +   A     Q    S  SSS   A A  A     AS S   
Sbjct: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938

Query: 245  HQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPL-NPISPLKKPFSSNVIAP 303
              +  AA   P +P GG  A   P+ A           PSP   P +P  K   +   A 
Sbjct: 939  APTPPAA--TPPSPKGG-PATPSPKWA---PTPPAATPPSPKGGPATPSPKGAPTPPAAT 992

Query: 304  PKFPRAAPLT 313
            P  P+  P T
Sbjct: 993  PPSPKGGPAT 1002



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 81/322 (25%), Positives = 109/322 (33%), Gaps = 40/322 (12%)

Query: 26   PQPESSVSEAPSTPLS--------SETPKP--------EENSAVPALSPAAAPPAPNGPD 69
            P P+ + + +  TPLS         ETP P        +E  A PA   A A    +   
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918

Query: 70   KMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGST-WSTGTTNAVEDSFFQGIT 128
            K    +P   G+     P+  P P     P     P+  S  W+     A   S   G  
Sbjct: 919  KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-- 976

Query: 129  PVNGTMLFQNFPHHVNPVF--GGTFSPQIGLAQTQHHQQPPPP----APAPQPAQPAQPP 182
            P   +      P    P    GG  +P    A T     PP P    A  P P   + PP
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036

Query: 183  QAQPPQQRRSPAS---PSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239
             A PP  + SPA+   P  AP    +   +    P   S   + +  AA   +     A+
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT 1096

Query: 240  SSWNTHQSVNAAWSAPSNPWGGL-----QAGRDPRRAVGVGVGVGVGVPSPLN-PISPLK 293
             S        AA   P +P GGL     +       A       G+  P P   P +P  
Sbjct: 1097 PSPKGAPMPPAA--TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 294  KPFS--SNVIAPPKFPRAAPLT 313
             P S    +  PP  P+ AP T
Sbjct: 1155 TPPSPKGGLATPP--PKGAPTT 1174



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 74/315 (23%), Positives = 106/315 (33%), Gaps = 35/315 (11%)

Query: 26   PQPESSVSEAPSTPLSSE----TPKPEENSAVPALSPA------AAPPAPNGPDKMQMES 75
            P P+ + +   +TP S +    TP P+     PA +P       A PP    P+   +  
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 76   PLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTML 135
            P   G     PP+  P P     P    SP         T  AV     +G TP      
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG-TP------ 1347

Query: 136  FQNFPHHVNPVFGGTFSPQ-----IGLAQTQHHQQPP---PPAPAPQPAQPAQPPQAQPP 187
                P       GG  +P         A T  H+  P   PP+P   PA P+  P+  P 
Sbjct: 1348 --TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPT 1403

Query: 188  QQRRSPASPSQAPYA----QRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243
                 P SP +AP      + +A  + G        P S     A +A     +  SS  
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 244  THQSVNAAWSAPSNPWGGLQ--AGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVI 301
                      +P  P    Q      P++A      +G      + P SP + P + +  
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523

Query: 302  APPKFPRAAPLTSKS 316
              P  P A  L+ K+
Sbjct: 1524 RDPIAPTATLLSKKT 1538



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 68/299 (22%), Positives = 101/299 (33%), Gaps = 57/299 (19%)

Query: 26   PQPESSVSEAPSTPLSSE----TPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGL 81
            P P+ + +   +TP S +    TP P+        +PAA PP+P G        P  P  
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKG----APTTPAATPPSPKG-------GPATP-- 1258

Query: 82   SFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPH 141
                PP+  P P  PAA   SL     +    G  N                      P 
Sbjct: 1259 ----PPKGAPTP--PAATPPSLKGGLATPPHKGAPN----------------------PA 1290

Query: 142  HVNPVFGGTFSPQIGLAQTQHHQQPPPPA---PAPQPAQPAQPPQAQPPQQRRSPASPSQ 198
             V P      SP+ G A +     P PPA   P+P+ +    PP+  P     +P SP  
Sbjct: 1291 VVTPP-----SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 199  APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258
             P    +  ++ G     +SK   +   A  +     +    S     ++ +    P++P
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405

Query: 259  WGGLQAGRDPRRAVGVGV-GVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316
                     P++A    V   G   PS  +   P   P S         P+  P T  S
Sbjct: 1406 ---AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 71/322 (22%), Positives = 104/322 (32%), Gaps = 26/322 (8%)

Query: 14   PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM 73
            P P+Q                 P+      +P P+     PA +P +    P  P     
Sbjct: 903  PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962

Query: 74   ESPLLPGLSFHQP---PQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPV 130
             +P  P  +   P   P  P P   P  P A+     G   +     A         +P 
Sbjct: 963  PTP--PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP- 1019

Query: 131  NGTMLFQNFPHHVN-PVFGGTFSPQIGLAQTQHHQQPPP------PAPAPQPAQPA---- 179
             G+     FP   + P      SP+   A T   +  P       P+P   PA P+    
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 180  -QPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSA 238
              PP A PP  +  PA+PS        AA     +  + + P   +    AA   +    
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 239  SSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV------GVGVPSPLN-PISP 291
             ++     +     + P +P GGL A   P+ A             G+  PSP   P +P
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 292  LKKPFSSNVIAPPKFPRAAPLT 313
               P S         P+ AP T
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTT 1220



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/194 (21%), Positives = 67/194 (34%), Gaps = 40/194 (20%)

Query: 12   TQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPK-----PEENSAVPALSPAAAPPAPN 66
            T P P++    +Q     SS  +AP+TP     P      P     VPA   +   P   
Sbjct: 1471 TPPSPKEPPAPKQVAT-SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529

Query: 67   GPDKMQMESP--LLPGLSFHQPPQQPPPPQE-PAAPGASLSPSFGSTWSTGTTNAVEDSF 123
                +  ++P  L P  +   P    P P++ PA P    +P+  S+    +  AV  S 
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589

Query: 124  FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183
            ++G       ++                               PP   +P P +   PP 
Sbjct: 1590 YKGAPSPKELLI-------------------------------PPAVTSPSPKEAPTPPA 1618

Query: 184  AQPPQQRRSPASPS 197
              PP   + PA+P+
Sbjct: 1619 VTPPSPEKGPATPA 1632



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 59/252 (23%), Positives = 87/252 (34%), Gaps = 43/252 (17%)

Query: 11   KTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVP-----ALSPAAAPPAP 65
            K  P P        +  P +S  +   TP ++  P P+ +   P        PA  PP+P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343

Query: 66   NGPDKMQMESPLLPG----------------LSFHQ--PPQQPPPPQE-PAAPGASLSPS 106
             G   +   +P   G                   H+  P   PP P+  PA P     P+
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 107  FGSTWSTGTTNAVEDSFFQ--GITPVNGTMLFQNFPHHVNPV----FGGTFSPQIGLAQT 160
              +        A      +    TP  G +     P  V PV       T +P+ G A  
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLT----PPAVTPVSLKKAPATSAPKGGPATP 1459

Query: 161  QHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKP 220
                +  P  PA  P  P +PP    P+Q  + +SP +AP    +  A  G   +    P
Sbjct: 1460 S--SKGDPTLPAVTPPSPKEPP---APKQVATSSSPKKAP----ATPAPMGAPTLPAVIP 1510

Query: 221  SSSSAVAAAAAA 232
            SS   V A  ++
Sbjct: 1511 SSPKEVPATPSS 1522



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 48/210 (22%), Positives = 75/210 (35%), Gaps = 35/210 (16%)

Query: 36   PSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPP-- 93
            P +P     PK    S+ P  +PA   PAP G       +P LP +    P + P  P  
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPAT--PAPMG-------APTLPAVIPSSPKEVPATPSS 1522

Query: 94   -QEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFS 152
             ++P AP A+L         T  T A +++       V         P           +
Sbjct: 1523 RRDPIAPTATLLSK-----KTPATLAPKEALIPPAMTVPSPKKTPAIP-----------T 1566

Query: 153  PQIGLAQTQHHQQPPPPAP-------APQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRS 205
            P+   A     +   PPA        AP P +   PP    P  + +P  P+  P +   
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626

Query: 206  AAAAYGHQPIMTSKPSSSSAVAAAAAAAAA 235
              A    +   TS P + S++  +  + A+
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 57/240 (23%), Positives = 72/240 (30%), Gaps = 58/240 (24%)

Query: 8    DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET--PKPEENSAVPALSPA-----A 60
            D SKT          +    P  S +  P T  + E   PKPE  S   A SP      A
Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803

Query: 61   APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 120
              P P  P K Q   P  PGL    P        +P AP                  A E
Sbjct: 1804 PSPVPTLPPKQQF-LPSSPGLVLESP-------SKPLAP------------------ADE 1837

Query: 121  DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA- 179
            D     I P               P+ GG     + L      +    P P P   QP  
Sbjct: 1838 DELLPLIPP--------------EPISGGVPFQSV-LVNMPTPKSAGIPVPTPSAKQPVT 1882

Query: 180  ---------QPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230
                            P+     ++ +    AQ +AAA    +P+  +K S S   A  A
Sbjct: 1883 KNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA 1942



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 75/341 (21%), Positives = 115/341 (33%), Gaps = 59/341 (17%)

Query: 4    DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET--------------PKPEE 49
            + L+  + T P P+   +    P P+    EAP+TP S E               P P+E
Sbjct: 1546 EALIPPAMTVPSPK---KTPAIPTPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 50   NSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSF-G 108
                  + PA   P+P        E+P  P ++   PP     P  PA  G   SP    
Sbjct: 1599 L----LIPPAVTSPSPK-------EAPTPPAVT---PPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 109  STWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNP-------VFGGTFSPQIGLAQTQ 161
            S+     T+    +   G T    +   +  P    P       V     S  I  A T+
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQAS---KGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701

Query: 162  HHQQ-------PPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQP 214
               Q        PP  P P     ++ P +        P     +  A+   A+     P
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761

Query: 215  IMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAP-SNPWGGLQAGRDPRRAVG 273
            +   +  +S+ + AAA         S+     SV+AA S P S P         P +   
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESA-----SVSAAPSPPVSLPLAPSPVPTLPPKQQF 1816

Query: 274  VGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTS 314
            +    G+ + SP  P++P  +     +I P       P  S
Sbjct: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 10/79 (12%)

Query: 166 PPPPAPAPQPAQPAQPPQAQP-PQQRRSPASPSQAPYAQRSAAAAY---------GHQPI 215
           PPP +PAPQ    +   QA P P      ++P + P+ Q S+  A             P 
Sbjct: 46  PPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN 105

Query: 216 MTSKPSSSSAVAAAAAAAA 234
           +   P S +A+A A+   A
Sbjct: 106 LIGPPISPAALALASPMIA 124



 Score = 29.6 bits (65), Expect = 9.9
 Identities = 75/301 (24%), Positives = 106/301 (35%), Gaps = 75/301 (24%)

Query: 31  SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPL--------LPGLS 82
           S S +P  PLS     PE   A  +L      P P G     M SPL        +   S
Sbjct: 575 STSSSPEIPLS-----PEATLAKKSLGE----PLPIGKPASSMTSPLGVNSSASVIKTDS 625

Query: 83  FHQPPQQPPP-------------PQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG--- 126
           +  P    P              P E A P A ++P+     ST TT A    F +G   
Sbjct: 626 YAGPDSAGPLLKSSLITPTVAAFPLESADP-AGVAPTTAKGTSTYTTTA--SPFLEGTVS 682

Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQP 186
           + P N            +PV  GT +    L       +  P AP+PQ            
Sbjct: 683 LAPKN------------HPVKEGTLTT---LPLVPTASENCPVAPSPQNTCAPLATLVLA 727

Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAA--------SSA 238
           P+  +S  SPS  P             P  T K    S  +A A  A++        S A
Sbjct: 728 PEIPKSVPSPSLPP----------AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777

Query: 239 SSSWNTHQSVNAAWSAPSNPWG---GLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKP 295
           S++ ++  ++     +PS P G     Q  R P +    G    +G  S  +P+SP++  
Sbjct: 778 SATASSKGTLTYLADSPS-PLGVSVSPQTKRPPTKKGSAGPDTPIGNLS--SPVSPVEAS 834

Query: 296 F 296
           F
Sbjct: 835 F 835


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 77/302 (25%), Positives = 102/302 (33%), Gaps = 40/302 (13%)

Query: 14   PQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPAL---------SPAAAPPA 64
            P P   +   + P    SVS  PS P     P P+    +P +          P A+ PA
Sbjct: 792  PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851

Query: 65   PNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFF 124
            P  P   Q   PL P     QPP+ P PP     P ++ S    S+ ++    A   S F
Sbjct: 852  PTAPGPPQ--PPLRPQ---SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906

Query: 125  QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQA 184
            Q             FP    P    T  P + L      +   PP P P+  Q    P  
Sbjct: 907  Q-----------LQFPPSQGPHKSPTPPPTLHLVP----EPAAPPPPPPRTFQMVTTPFP 951

Query: 185  QPPQQRRSPASPSQAP---YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSS 241
              PQ +       Q P     Q  A  A       TS    +S  A+   +  A S + +
Sbjct: 952  ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011

Query: 242  WNTHQSVNAAWSAPSNP-----WGGLQAGRDPRRAVGVGVGVGVGVPSPL---NPISPLK 293
              +H    A  +A   P          A   P   V      G G PS L   + +S LK
Sbjct: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071

Query: 294  KP 295
            KP
Sbjct: 1072 KP 1073



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 58/209 (27%), Positives = 79/209 (37%), Gaps = 44/209 (21%)

Query: 28  PESSVSEAPSTPLSSET---PKPEENSAVPALSP---AAAP---PAPNGPDKMQMESPLL 78
           P  +   AP+TP++      P+  ++ A PA +P   AAAP   P P+    +  ++PL 
Sbjct: 727 PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPL- 785

Query: 79  PGLSFHQPPQQPP-PPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQ 137
            G S H P   P  PP  P +   S+S                        P +   L  
Sbjct: 786 -GDSPHLPSPHPTRPPSRPPSRPQSVS-----------------------RPPSEPPLHP 821

Query: 138 NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP---PQAQPPQQRRSPA 194
             P    P   G F     + Q Q    PP   PAP    P QP   PQ+QPP+    PA
Sbjct: 822 CPPPQAPPTLPGIF-----VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA 876

Query: 195 SPSQAPYAQRSAAAAYGHQPIMTSKPSSS 223
            P   P +  SA A+          P+ S
Sbjct: 877 -PHLPPSSTSSAVASSSETSSRLPAPTPS 904



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 54/206 (26%), Positives = 71/206 (34%), Gaps = 45/206 (21%)

Query: 15  QPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQM- 73
           QPQ QQ   Q P P+++     +TP  S          V    P+A P A    D +QM 
Sbjct: 641 QPQAQQ-PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF 699

Query: 74  ------ESPLL---PGLSF-------HQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTN 117
                 + PL    P LS          PP Q P P  P A GA L P    +      +
Sbjct: 700 LPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS----QAS 755

Query: 118 AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP---PPPAPAPQ 174
                      P+ G               G + SP +       HQ P    P  P+P 
Sbjct: 756 PAPAPQIPAAAPLKGP--------------GPSSSPSL------PHQAPLGDSPHLPSPH 795

Query: 175 PAQPAQPPQAQPPQQRRSPASPSQAP 200
           P +P   P ++P    R P+ P   P
Sbjct: 796 PTRPPSRPPSRPQSVSRPPSEPPLHP 821



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 80/304 (26%), Positives = 105/304 (34%), Gaps = 38/304 (12%)

Query: 28  PESSVS--EAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQ 85
           P S+V+    P   +   TP      A P L+   AP AP       + +PL  GL   Q
Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA-----VSTPLPLGL---Q 640

Query: 86  PPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNP 145
            PQ   PPQ P    A+   +     S G  ++ E            T +       +  
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQ--DSLQM 698

Query: 146 VFGGTFSPQIGLAQTQHHQQP-------PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQ 198
                 S Q   A+  H   P       PPPA  P PA P        PQ   S ASP+ 
Sbjct: 699 FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAP 758

Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTH---------QSVN 249
           AP  Q  AAA     P+    PSSS ++   A    +    S   T          QSV+
Sbjct: 759 AP--QIPAAA-----PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS 811

Query: 250 AAWSAPSNPWGGLQAGRDPRRAVGVGVGVG-VGVPSPLNPISPLKKPFSSNVIAPPKFPR 308
              S P  P       + P    G+ V    +GVP P +  +P         + P   P 
Sbjct: 812 RPPSEP--PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP 869

Query: 309 AAPL 312
             PL
Sbjct: 870 EGPL 873



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 54/244 (22%), Positives = 87/244 (35%), Gaps = 30/244 (12%)

Query: 1    MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 60
            +Q+ L +    + P P      Q   +P+S   E P  P     P    ++   +   ++
Sbjct: 837  IQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSS 896

Query: 61   APPAPNGPDKMQMESPLLPGLSFHQPPQQPPP---PQEPAAPGASLSPSFGSTWSTGTTN 117
              PAP  P   Q++ P  P    H+ P  PP      EPAAP      +F    +     
Sbjct: 897  RLPAPT-PSDFQLQFP--PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPAL 953

Query: 118  AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQ 177
                +  +    V   ++ Q      N   G   +PQ   +        P  +PA     
Sbjct: 954  PQPKALLERFHQVPSGIILQ------NKAGGAPAAPQTSTS------LGPLTSPAASVLV 1001

Query: 178  PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237
              Q P         +P +PS AP    +  AA G  P++   P+ + A A+       + 
Sbjct: 1002 SGQAPSG-------TPTAPSHAP--APAPMAATGLPPLL---PAENKAFASNLPTLNVAK 1049

Query: 238  ASSS 241
            A+SS
Sbjct: 1050 AASS 1053



 Score = 38.1 bits (87), Expect = 0.028
 Identities = 50/217 (23%), Positives = 83/217 (38%), Gaps = 32/217 (14%)

Query: 1    MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPL--SSETPKPEENSAVPALSP 58
            M D + + + KT      +Q  +++P    S S +   P+  SSE  +   +  + + +P
Sbjct: 1174 MIDRMFIQEEKTT-LALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAP 1232

Query: 59   AAAP-PAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTN 117
             A+  P P+ P K+ +      G           P    A   +SLS S  S+ +  + +
Sbjct: 1233 GASTQPPPHLPTKLVIRHGGAGG----------SPSVTWARASSSLSSSSSSSSAASSLD 1282

Query: 118  AVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH-------HQQPPPPA 170
            A ED    G  P       + +              + GL++  H       HQ PPPPA
Sbjct: 1283 ADED----GPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPA 1338

Query: 171  PAPQPAQPAQPPQAQPPQQRRS-------PASPSQAP 200
                   P +PP   PP  + +       PA+P + P
Sbjct: 1339 TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKP 1375



 Score = 36.6 bits (83), Expect = 0.081
 Identities = 96/401 (23%), Positives = 126/401 (31%), Gaps = 116/401 (28%)

Query: 13  QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAV----PALSPAAAPPAPNGP 68
           +P    QQ +  Q     +  +A    + S  P P   + V    PA +  AAPP P G 
Sbjct: 383 EPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGA 442

Query: 69  DKMQMESPLL-PGLSFHQPPQQPPPPQE----PAAPGASLSPSFGSTWST--GTTNAVED 121
               M   LL  G S   P Q   P Q     P AP   L     +  +   G   A   
Sbjct: 443 LSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAA 502

Query: 122 SFFQGITPVNGTMLFQNF--PHHVNPVFG---------------------GTFSPQIGLA 158
               G    N  +  QN   P  + PV                         F   + LA
Sbjct: 503 PHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLA 562

Query: 159 --QTQHHQQPPPPAPAP------------------------QPAQPA------------Q 180
                   QP P  PA                         QPA PA            Q
Sbjct: 563 AGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQ 622

Query: 181 P-PQAQP------------PQQRRSP-------ASPSQAPYAQRSAAAAYGHQPIMTSKP 220
           P PQA P            PQ ++ P       A+P QA   Q S   A   + I+  +P
Sbjct: 623 PAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682

Query: 221 SSSSAVAAAAAAA--------AASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAV 272
            S++  A     +         +    S+   H SV A+    + P       +DP  A 
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP-----PAQDPAPAT 737

Query: 273 GVGVGVGVGVPSPLNPISPLKKPFSSNVIAP-PKFPRAAPL 312
            V  G G+G  +P +  SP          AP P+ P AAPL
Sbjct: 738 PVAKGAGLGPQAPDSQASP----------APAPQIPAAAPL 768


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 76/265 (28%), Positives = 104/265 (39%), Gaps = 32/265 (12%)

Query: 24  QQPQPESS----VSEAPSTPLSSETPKPEENSAVPALSPAAAP------PAPNGPDKMQM 73
           Q+P P S     V   P+ P +   P PE ++   A  PAAA       PAP GP K   
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162

Query: 74  ESPLL----PGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITP 129
            + L     PG      P   P P +PA PGA+ + + GS     + +A   +    ++ 
Sbjct: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLN-GSAALLNSHHAAAPA----VSL 217

Query: 130 VN-GTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQ 188
           VN G       P    P       P +G A       P P AP+P  A     P A PP 
Sbjct: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP-----PAPAAPSPPAAPAPAAPAAAPPP 272

Query: 189 QRRSPASPSQAP-YAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS 247
              +PA+ ++ P +      AA    P   ++   S+  A A A AA   A  S      
Sbjct: 273 PPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG 332

Query: 248 VNAAWSAPSNPWGGLQAGRDPRRAV 272
             AA  AP     G++A   P+R V
Sbjct: 333 AAAAAPAP-----GVKA-ESPKRVV 351



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 53/222 (23%), Positives = 86/222 (38%), Gaps = 15/222 (6%)

Query: 25  QPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFH 84
           QP P ++ + AP+  + +E+PK      V A  PAA   A +GP        + P +   
Sbjct: 328 QPGPGAAAA-APAPGVKAESPK----RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382

Query: 85  QPPQQPPPPQEPAAPGASLSPSFGSTWS--TGTTNAVEDSFFQGITPVNGTMLFQNFPHH 142
            P     PP  P  P      + G+     + T  A        +TP          P +
Sbjct: 383 LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQN 442

Query: 143 VNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQP-AQPPQAQPPQQRRSPASPSQA 199
              +      P + L ++++ Q    P  A A   AQ  AQP     P+    PA+P+ A
Sbjct: 443 PTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPR----PATPTSA 498

Query: 200 PYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSS 241
           P  Q S   A G  PI+  + + ++ +   + A      S++
Sbjct: 499 PPVQISTVQAPG-TPIIARQVTPTTIIKQVSQAQTTVQPSAT 539



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 43/149 (28%), Positives = 55/149 (36%), Gaps = 14/149 (9%)

Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQP----PQAQ-PPQQRRSPASPSQ 198
           N V  G+ +   G       +  P  AP P PA  A+P    PQ   PP  RR       
Sbjct: 60  NHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGP 119

Query: 199 APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNP 258
           AP A +        +P       S + V AAAA AA    + +     +  AA +A + P
Sbjct: 120 APPAAKL-------RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172

Query: 259 WGGLQAGRDPRRAVGVGVGVGVGVPSPLN 287
             G   G  P    G G   G G    LN
Sbjct: 173 GPG--PGPGPGPGPGPGKPAGPGAAQTLN 199



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 50/210 (23%), Positives = 65/210 (30%), Gaps = 57/210 (27%)

Query: 23  QQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLS 82
           Q  P   ++   AP+ P     P P    A PA +P   PPAP                +
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAP----AAPAAAPPPPPPAP---------------AT 279

Query: 83  FHQPPQQP--PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFP 140
             +PP  P  PP   PA P  + + + GS                G  P           
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSA---------------GAAPAPA-------- 316

Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAP 200
               P  GG               QP P A A  PA   +    +   Q   PA+ + A 
Sbjct: 317 ----PAAGGPAGVS---------GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363

Query: 201 YAQRSAAAAYGHQPIMTSKPSSSSAVAAAA 230
               S AA+    P M     S +AV   A
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAAVPPPA 393



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 7/87 (8%)

Query: 19  QQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLL 78
           QQ QQQ P P S  + A +  + S + +         ++ A  PP       + +  P  
Sbjct: 676 QQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPV------LSLTQPTQ 729

Query: 79  PGLSFHQPPQQPPPPQEPAAPGASLSP 105
            G+     P  P   Q+P  PGA + P
Sbjct: 730 VGVGKQGQP-TPLVIQQPPKPGALIRP 755


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%)

Query: 8   DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62
           D         QQQ  Q QP   Q  + V+ APS+  P + + P P    +  A+ P  +P
Sbjct: 166 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 225

Query: 63  PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116
            A   P++ Q  +  +P     Q     PQ+PP P  P   +P   L P  GS       
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 285

Query: 117 NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169
           +  +        P   ++       H  P       PQ       +G +    +      
Sbjct: 286 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345

Query: 170 APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224
            PA Q A Q  QPP+ QP    P        P   P  Q  A  A+ H P + S PS  S
Sbjct: 346 LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 404

Query: 225 AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271
            + A      A    SS +TH   +A               S+P+ P G  Q+   P   
Sbjct: 405 -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463

Query: 272 VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316
                      P+ L+ ++P + PF+ +   P   P   P T  S
Sbjct: 464 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 500



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%)

Query: 18  QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74
           Q   Q QQP  E  +   P  PL+    KP   + +P L    A   PP  +GP    M 
Sbjct: 350 QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406

Query: 75  SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126
           + L P         LS H PP   PPP +   P +   PS       G T +        
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 456

Query: 127 ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182
                     QN P            P      T  HQ  P P  A  P  P  PP    
Sbjct: 457 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495

Query: 183 -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211
                 + PP     P + +Q P    S AAA G
Sbjct: 496 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 523


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%)

Query: 8    DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62
            D         QQQ  Q QP   Q  + V+ APS+  P + + P P    +  A+ P  +P
Sbjct: 720  DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779

Query: 63   PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116
             A   P++ Q  +  +P     Q     PQ+PP P  P   +P   L P  GS       
Sbjct: 780  TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839

Query: 117  NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169
            +  +        P   ++       H  P       PQ       +G +    +      
Sbjct: 840  SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 170  APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224
             PA Q A Q  QPP+ QP    P        P   P  Q  A  A+ H P + S PS  S
Sbjct: 900  LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 958

Query: 225  AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271
             + A      A    SS +TH   +A               S+P+ P G  Q+   P   
Sbjct: 959  -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 272  VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316
                       P+ L+ ++P + PF+ +   P   P   P T  S
Sbjct: 1018 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 1054



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%)

Query: 18   QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74
            Q   Q QQP  E  +   P  PL+    KP   + +P L    A   PP  +GP    M 
Sbjct: 904  QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 75   SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126
            + L P         LS H PP   PPP +   P +   PS       G T +        
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 1010

Query: 127  ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182
                      QN P            P      T  HQ  P P  A  P  P  PP    
Sbjct: 1011 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 183  -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211
                  + PP     P + +Q P    S AAA G
Sbjct: 1050 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 1077


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 46/345 (13%)

Query: 8    DKSKTQPQPQQQQRQQQQP---QPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAP 62
            D         QQQ  Q QP   Q  + V+ APS+  P + + P P    +  A+ P  +P
Sbjct: 720  DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779

Query: 63   PAPNGPDKMQMESPLLPGLSFHQP----PQQPPPPQEP--AAPGASLSPSFGSTWSTGTT 116
             A   P++ Q  +  +P     Q     PQ+PP P  P   +P   L P  GS       
Sbjct: 780  TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839

Query: 117  NAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQ-------IGLAQTQHHQQPPPP 169
            +  +        P   ++       H  P       PQ       +G +    +      
Sbjct: 840  SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 170  APAPQPA-QPAQPPQAQP----PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSS 224
             PA Q A Q  QPP+ QP    P        P   P  Q  A  A+ H P + S PS  S
Sbjct: 900  LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL-SGPSPFS 958

Query: 225  AVAAAAAAAAASSASSSWNTHQSVNA-------------AWSAPSNPWGGLQAGRDPRRA 271
             + A      A    SS +TH   +A               S+P+ P G  Q+   P   
Sbjct: 959  -MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 272  VGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKS 316
                       P+ L+ ++P + PF+ +   P   P   P T  S
Sbjct: 1018 AS-------HPPTGLHQVAP-QPPFAQHPFVPGGPPPITPPTCPS 1054



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 58/214 (27%), Positives = 70/214 (32%), Gaps = 60/214 (28%)

Query: 18   QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74
            Q   Q QQP  E  +   P  PL+    KP   + +P L    A   PP  +GP    M 
Sbjct: 904  QSALQSQQPPREQPL---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 75   SPLLP--------GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQG 126
            + L P         LS H PP   PPP +   P +   PS       G T +        
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQ-LMPQSQPLPS-SPAQPPGLTQS-------- 1010

Query: 127  ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPP---- 182
                      QN P            P      T  HQ  P P  A  P  P  PP    
Sbjct: 1011 ----------QNLP-----------PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 183  -----QAQPPQQRRSPASPSQAPYAQRSAAAAYG 211
                  + PP     P + +Q P    S AAA G
Sbjct: 1050 PTCPSTSTPP---AGPGTSAQPPC---SGAAASG 1077


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 68/263 (25%), Positives = 96/263 (36%), Gaps = 43/263 (16%)

Query: 14  PQPQQQQRQQQQPQPESSVSEAPSTPLSS--------------ETPKPEENSAVPALSPA 59
           P P      +  P P  S S  P+ P SS              +  +  +      L P 
Sbjct: 20  PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPH 79

Query: 60  AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119
             PP P  P       P++PG  +     QPPPP  P  PG +LS      +     +  
Sbjct: 80  HLPPPPLPPP------PVMPGGGYGD--WQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131

Query: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179
            D    G+ P+         P    PV  G++ P      +Q +  PP P P+  P   +
Sbjct: 132 RDGP-PGLVPME-----LESPPESPPVPPGSYMPP-----SQSYMPPPQPPPSYYPPTSS 180

Query: 180 QP--PQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237
           QP  P AQP        SPSQ+P +Q   A    +    +S  S  S   +   ++ AS 
Sbjct: 181 QPYLPPAQP--------SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232

Query: 238 ASSSWNTHQSVNAAWSAPSNPWG 260
           +  S    +S   A   PS P G
Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPG 255



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 62/262 (23%), Positives = 89/262 (33%), Gaps = 30/262 (11%)

Query: 7   MDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPN 66
           M  +++  Q +    Q  + Q   ++S  P     S+ P P      P L P+  PP   
Sbjct: 489 MKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPP--- 545

Query: 67  GPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSF-GSTWSTGTTNAVEDSFFQ 125
                 +  P LP      PP  PPP   P+ P +   P    S  S G    +      
Sbjct: 546 ------VMPPALPATV--PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLS 597

Query: 126 GITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQ 185
              P          P    P    T  P +          PPP  P P   Q   P    
Sbjct: 598 SAGPP---------PVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTA 648

Query: 186 PPQQRRSPASPSQAPYAQRSA----AAAYGHQPIMTSKPSSSSA-----VAAAAAAAAAS 236
            P    S +  SQ P   R A      ++G  P  T  P   SA     V + A  + ++
Sbjct: 649 APVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSA 708

Query: 237 SASSSWNTHQSVNAAWSAPSNP 258
              SS+++ Q +  + +APS P
Sbjct: 709 LPYSSFSSDQGLGESSAAPSQP 730



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 61/233 (26%), Positives = 86/233 (36%), Gaps = 54/233 (23%)

Query: 80  GLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQ-- 137
           G S H PP   PPP   A P AS  P +    S+ T  A   S F      +   L Q  
Sbjct: 9   GGSSHYPPPPVPPPPPVALPEASPGPGYS---SSTTPAAPSSSGFMSFREQHLAQLQQLQ 65

Query: 138 ----------NFPHHVNP--------VFGGTFS----------PQIGLA----------- 158
                       PHH+ P        + GG +           P  G A           
Sbjct: 66  QMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH 125

Query: 159 QTQHHQQPPPPAPAPQ-----PAQPAQPPQA-QPPQQRRSPASPSQAPYAQRSAAAAY-- 210
           Q  HHQ+  PP   P      P  P  PP +  PP Q   P       Y   +++  Y  
Sbjct: 126 QMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP 185

Query: 211 GHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS--VNAAWSAPSNPWGG 261
             QP  +  P S S +A   + +++SS+S S+ +H    + ++ ++PS P  G
Sbjct: 186 PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG 238



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 46/205 (22%), Positives = 69/205 (33%), Gaps = 28/205 (13%)

Query: 18   QQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAA---PPAPNGPDKMQME 74
            ++Q++Q Q   +       +  L  +  + +  S+ P + P      PP P G     + 
Sbjct: 1467 REQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIV 1526

Query: 75   SPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS----FGSTWSTGTTNAVEDSFFQGITPV 130
             P  P      P  +PP P  P  P   L P        T +       EDSF+ G+   
Sbjct: 1527 RPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFY-GLWDT 1585

Query: 131  NGTM-LFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQ 189
            N    L   F      +      P   +     H   PPP P P       PP ++PP  
Sbjct: 1586 NDEQGLNSEFKSETAAIPSAPVLPPPPV-----HSSIPPPGPVPM----GMPPMSKPPPV 1636

Query: 190  RR----------SPASPSQAPYAQR 204
            ++          S     Q PY +R
Sbjct: 1637 QQTVDYGHGRDISTNKVEQIPYGER 1661



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 24/215 (11%)

Query: 13  QPQPQQQQRQQQQPQPESSVSEAPSTP----------LSSETPKPEENSAVPALSPAAAP 62
           QP P Q    Q    P  S S + S+           L S    P   S   + S   AP
Sbjct: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP 247

Query: 63  PAPNGPDKMQ---MESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119
           P P+ P   +    + PL  G       QQ   P+    P           W      ++
Sbjct: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD--PSTMTPQEQQQYWYRQHLLSL 305

Query: 120 EDSFFQGITP-VNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQP 178
           +      +     G ++ ++ P  V        + Q+  + +      PPP     P  P
Sbjct: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365

Query: 179 AQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQ 213
            + PQ++ P++         A   Q  AAAA+  Q
Sbjct: 366 PEEPQSEDPEE--------DARLKQLQAAAAHWQQ 392



 Score = 33.9 bits (76), Expect = 0.52
 Identities = 40/185 (21%), Positives = 65/185 (35%), Gaps = 31/185 (16%)

Query: 167 PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAV 226
           PPP   P    P+ P    PP    S +S    P     + ++ G  P++     SS+A 
Sbjct: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615

Query: 227 AAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPL 286
                    SSA+               P  P  G+  G  P+              +P+
Sbjct: 616 PPVMPLPPLSSAT-------------PPPGIPPPGVPQGIPPQLTA-----------APV 651

Query: 287 NPISPL------KKPFSSNVIAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRP 340
            P S        +KP  + +  P  F  A P T    ++ +A  ++  N+  P    + P
Sbjct: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQ-SAGPSEQVNSKAPLSKSALP 710

Query: 341 YDTFN 345
           Y +F+
Sbjct: 711 YSSFS 715



 Score = 29.6 bits (65), Expect = 9.9
 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 15/99 (15%)

Query: 8   DKSKTQPQPQQQQRQQQ-----QPQPESSVSEAPSTPL-SSETPKP-EENSAVPALSPAA 60
           D S   PQ QQQ   +Q     Q + +  +      P+ + +TP+P +E   VPA S   
Sbjct: 284 DPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV- 342

Query: 61  APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAP 99
                  P+    E P LP  +   PP  PP   +   P
Sbjct: 343 -------PESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 59/186 (31%), Positives = 77/186 (41%), Gaps = 39/186 (20%)

Query: 9   KSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAP-PAPNG 67
           K++ Q Q QQQQ+QQQQ Q + + S AP                VP + PA  P PAP G
Sbjct: 425 KAQQQQQQQQQQQQQQQQQQQQAASVAP----------------VPTMPPALQPFPAPVG 468

Query: 68  P-DKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPS-----FGSTWSTGTTNAVED 121
           P D    +      ++   PP    PP  PA PG    P       G T S    NA   
Sbjct: 469 PFDAAPAQ------VAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCS 522

Query: 122 SFFQGITPVNGTMLFQ--NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPA 179
           +    + P   T+L +   FP    P   G+       A+ + +  P PP PAP PA   
Sbjct: 523 A--AQLQPQPATLLGKAGAFPPPAIPSAPGS------QARPRPNGAPWPPEPAPAPAPEL 574

Query: 180 QPPQAQ 185
            P +AQ
Sbjct: 575 DPFEAQ 580



 Score = 30.4 bits (67), Expect = 5.8
 Identities = 63/259 (24%), Positives = 79/259 (30%), Gaps = 47/259 (18%)

Query: 59  AAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNA 118
           +A  PAP  P       P   G S    P  PP       PG   +PS    W    +  
Sbjct: 373 SAGAPAPGPP-------PATTGTSAWGEPSVPPAAA--FQPGHKRTPSEAERWLEEVSQV 423

Query: 119 VEDSFFQ------------------GITPVNGTM--LFQNFPHHVNPVFGGTFSPQIGLA 158
            +    Q                   + PV  TM    Q FP  V P         + L 
Sbjct: 424 AKAQQQQQQQQQQQQQQQQQQQQAASVAPVP-TMPPALQPFPAPVGPFDAAPAQVAVFL- 481

Query: 159 QTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTS 218
                   PPP   P P  PA P    PP  R      + +     +  +A   QP    
Sbjct: 482 --------PPPHMQP-PFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQP---- 528

Query: 219 KPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGV 278
           +P++    A A    A  SA  S    +   A W  P  P        DP  A    +  
Sbjct: 529 QPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPW--PPEPAPAPAPELDPFEAQWAALEG 586

Query: 279 GVGVPSPLNPIS-PLKKPF 296
              V  P NP S  L+K F
Sbjct: 587 KATVEKPSNPFSGDLQKTF 605


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 99/431 (22%), Positives = 142/431 (32%), Gaps = 102/431 (23%)

Query: 4   DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET---PKPEENSAVPALSPAA 60
           D+  D   T P        +      S +S+ P+ P        P P+   + P    A+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182

Query: 61  APPAPNGPDKMQMESPLLPGLS--FHQPPQQPPP----------------PQEPAAPGAS 102
             P P+        +P+ P  S  F  PP  PPP                P  P   GA+
Sbjct: 183 FEPHPS-VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241

Query: 103 LS---PSFGSTWSTGTTN-AVEDSFFQGI-------TPVNGTMLFQ-----NFPH----- 141
            S   P+ G      TT  +V  S   G        TPV G  L       NFPH     
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301

Query: 142 ----HVNPVFGGTFSPQ-IGLAQTQHHQQPP----------PPAPAPQPAQPAQPPQAQP 186
                + P+   + SP  +G      H   P          PP P   P   A  P + P
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-APSPHSLP 360

Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQ 246
           P    +PA P + PY                    SSS+ ++AAA++++SS+SSS +   
Sbjct: 361 PASSSAPAPPMRFPY--------------------SSSSSSSAAASSSSSSSSSSASPFP 400

Query: 247 SVNAAWSAPSN--PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPP 304
           +  A  S P +  P   L     P              P    P  P +  +S     PP
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQP--------------PKYTQPSLPSQAVWSQGPPPPP 446

Query: 305 KFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPL 364
            + R   L + S      F    G           P  T + H  +       +   +  
Sbjct: 447 PYGR---LLANSNAHPGPFPPSTGAQ----STAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 365 KGKHYPPSGPP 375
           + +H+  SGPP
Sbjct: 500 QQQHHGNSGPP 510



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 71/287 (24%), Positives = 98/287 (34%), Gaps = 39/287 (13%)

Query: 13  QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQ 72
           Q Q QQQQ+QQQQ Q +         P     P P E  +     P A  P+      + 
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS------LG 537

Query: 73  MESPLLPGLSFHQPPQQPPPPQE-------PAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125
              P  PG     P   PPP  +       P  P  S S +  S+ S G+      S  Q
Sbjct: 538 SLRPYPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592

Query: 126 GITPVNGTMLFQNFP------HHVNPVFGGTFSPQIGLAQTQHHQQPPP---PAPAPQPA 176
           G  P      F   P        ++ V     S   G  +T     PPP    AP+P   
Sbjct: 593 G--PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPPYGKRAPSPGAY 649

Query: 177 QPAQPP---QAQPPQQRRSP------ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227
           + A PP      PP  R          SP   P   +  +   G  P+  + PS   ++ 
Sbjct: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709

Query: 228 AAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274
              AA A+    S+    Q     +  P +P    ++   P + V V
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 55/235 (23%), Positives = 76/235 (32%), Gaps = 41/235 (17%)

Query: 14  PQPQQQQRQQQQ----PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69
           P P  Q    Q     P   SS + + ST   S        S  P  +P   PP P    
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609

Query: 70  KMQMESPLLP-------GLSFHQPPQQPPPPQEPAAPGA-------SLSPSFGSTWSTGT 115
                S ++        G     PP  PP  +   +PGA          P    ++ TGT
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669

Query: 116 TNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTF---SPQIGLAQTQHHQQPPPPAPA 172
                   ++G +P               P   GTF   SP +G            P+  
Sbjct: 670 PPG-----YRGTSP---------------PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709

Query: 173 PQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227
           P PA PA  P     Q ++ PA   + P +    A +    P +   PS +S  A
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764



 Score = 30.8 bits (68), Expect = 4.4
 Identities = 53/225 (23%), Positives = 80/225 (35%), Gaps = 26/225 (11%)

Query: 8    DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67
            +K + + + ++ +R  +  Q   +  E PS       P  E  SAV  + P   P  P  
Sbjct: 824  EKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPAL 883

Query: 68   PDKMQMESP--LLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWST--GTTNAVEDSF 123
                +   P  + PG   H P   P    +P   G ++   + S  +       A E   
Sbjct: 884  RTLSEYARPHVMSPGNRNH-PFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDL 942

Query: 124  FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHH----QQPPPPAPAPQPAQPA 179
               + P      F+  P  + P+ G    P  GL     H     QP PP   P P  P+
Sbjct: 943  RDRLKPG-----FEVKPSELEPLHG---VPGPGLDPFPRHGGLALQPGPPGLHPFPFHPS 994

Query: 180  QPP-QAQPPQQRRSPASPSQAPYAQRSAA--------AAYGHQPI 215
              P + +       PA      YA+R AA        AA G+ P+
Sbjct: 995  LGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPL 1039


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 99/431 (22%), Positives = 142/431 (32%), Gaps = 102/431 (23%)

Query: 4   DLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSET---PKPEENSAVPALSPAA 60
           D+  D   T P        +      S +S+ P+ P        P P+   + P    A+
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182

Query: 61  APPAPNGPDKMQMESPLLPGLS--FHQPPQQPPP----------------PQEPAAPGAS 102
             P P+        +P+ P  S  F  PP  PPP                P  P   GA+
Sbjct: 183 FEPHPS-VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241

Query: 103 LS---PSFGSTWSTGTTN-AVEDSFFQGI-------TPVNGTMLFQ-----NFPH----- 141
            S   P+ G      TT  +V  S   G        TPV G  L       NFPH     
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301

Query: 142 ----HVNPVFGGTFSPQ-IGLAQTQHHQQPP----------PPAPAPQPAQPAQPPQAQP 186
                + P+   + SP  +G      H   P          PP P   P   A  P + P
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-APSPHSLP 360

Query: 187 PQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQ 246
           P    +PA P + PY                    SSS+ ++AAA++++SS+SSS +   
Sbjct: 361 PASSSAPAPPMRFPY--------------------SSSSSSSAAASSSSSSSSSSASPFP 400

Query: 247 SVNAAWSAPSN--PWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPP 304
           +  A  S P +  P   L     P              P    P  P +  +S     PP
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQP--------------PKYTQPSLPSQAVWSQGPPPPP 446

Query: 305 KFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPL 364
            + R   L + S      F    G           P  T + H  +       +   +  
Sbjct: 447 PYGR---LLANSNAHPGPFPPSTGAQ----STAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 365 KGKHYPPSGPP 375
           + +H+  SGPP
Sbjct: 500 QQQHHGNSGPP 510



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 71/287 (24%), Positives = 98/287 (34%), Gaps = 39/287 (13%)

Query: 13  QPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQ 72
           Q Q QQQQ+QQQQ Q +         P     P P E  +     P A  P+      + 
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS------LG 537

Query: 73  MESPLLPGLSFHQPPQQPPPPQE-------PAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125
              P  PG     P   PPP  +       P  P  S S +  S+ S G+      S  Q
Sbjct: 538 SLRPYPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592

Query: 126 GITPVNGTMLFQNFP------HHVNPVFGGTFSPQIGLAQTQHHQQPPP---PAPAPQPA 176
           G  P      F   P        ++ V     S   G  +T     PPP    AP+P   
Sbjct: 593 G--PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPPYGKRAPSPGAY 649

Query: 177 QPAQPP---QAQPPQQRRSP------ASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227
           + A PP      PP  R          SP   P   +  +   G  P+  + PS   ++ 
Sbjct: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709

Query: 228 AAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGV 274
              AA A+    S+    Q     +  P +P    ++   P + V V
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 55/235 (23%), Positives = 76/235 (32%), Gaps = 41/235 (17%)

Query: 14  PQPQQQQRQQQQ----PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPD 69
           P P  Q    Q     P   SS + + ST   S        S  P  +P   PP P    
Sbjct: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609

Query: 70  KMQMESPLLP-------GLSFHQPPQQPPPPQEPAAPGA-------SLSPSFGSTWSTGT 115
                S ++        G     PP  PP  +   +PGA          P    ++ TGT
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669

Query: 116 TNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTF---SPQIGLAQTQHHQQPPPPAPA 172
                   ++G +P               P   GTF   SP +G            P+  
Sbjct: 670 PPG-----YRGTSP---------------PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709

Query: 173 PQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVA 227
           P PA PA  P     Q ++ PA   + P +    A +    P +   PS +S  A
Sbjct: 710 PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764



 Score = 30.8 bits (68), Expect = 4.4
 Identities = 53/225 (23%), Positives = 80/225 (35%), Gaps = 26/225 (11%)

Query: 8    DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67
            +K + + + ++ +R  +  Q   +  E PS       P  E  SAV  + P   P  P  
Sbjct: 824  EKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPAL 883

Query: 68   PDKMQMESP--LLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWST--GTTNAVEDSF 123
                +   P  + PG   H P   P    +P   G ++   + S  +       A E   
Sbjct: 884  RTLSEYARPHVMSPGNRNH-PFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDL 942

Query: 124  FQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHH----QQPPPPAPAPQPAQPA 179
               + P      F+  P  + P+ G    P  GL     H     QP PP   P P  P+
Sbjct: 943  RDRLKPG-----FEVKPSELEPLHG---VPGPGLDPFPRHGGLALQPGPPGLHPFPFHPS 994

Query: 180  QPP-QAQPPQQRRSPASPSQAPYAQRSAA--------AAYGHQPI 215
              P + +       PA      YA+R AA        AA G+ P+
Sbjct: 995  LGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPL 1039


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 74/299 (24%), Positives = 96/299 (32%), Gaps = 26/299 (8%)

Query: 10  SKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAP--PAPNG 67
           +K Q  P    + Q  P    +  + P  P   + P P+ + +    SP   P  P P G
Sbjct: 45  NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104

Query: 68  PDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI 127
            ++ Q   P  PG     PPQ    PQ P  PG    P      S    +       QG 
Sbjct: 105 GNQPQGPPPP-PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP--QGP 161

Query: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQ--PAQ-------- 177
            P  G     N P    P  G    PQ    Q     Q PPP   PQ  P Q        
Sbjct: 162 PPQGG-----NQPQGPPPPPG---KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213

Query: 178 -PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAAS 236
            P   PQ  PPQ    P  P   P   +      G++P     P       A   + + S
Sbjct: 214 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQS 273

Query: 237 SASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKP 295
           + S             + P  P     AG +P++      G   G P P     P + P
Sbjct: 274 ARSPPGKPQGPPQQEGNNPQGP--PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 52/176 (29%), Positives = 69/176 (39%), Gaps = 17/176 (9%)

Query: 13  QPQ-PQQQQRQQQQPQPESSVS-EAPSTPLSSETPKPEENSAVPALSPAAAP--PAPNGP 68
           QPQ P     + Q P P+     + P  P   + P P+ + +  + SP   P  P P G 
Sbjct: 168 QPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG 227

Query: 69  DKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSP-SFGSTWSTGTTNAVEDSFFQGI 127
           ++ Q   P  PG     PPQ    PQ P  PG    P + G + S    +       QG 
Sbjct: 228 NQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP--QGP 284

Query: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183
               G     N P    P  GG  +PQ    Q     QP  P   PQ  +P++PPQ
Sbjct: 285 PQQEG-----NNPQGPPPPAGG--NPQ--QPQAPPAGQPQGPPRPPQGGRPSRPPQ 331



 Score = 30.8 bits (68), Expect = 4.4
 Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 14/63 (22%)

Query: 152 SPQIGLAQTQHHQQPPPPAPA------------PQPAQPAQPPQAQPPQ--QRRSPASPS 197
           +PQ    Q  +  Q PPP P             PQ   P   PQ  PPQ  + RSP SP 
Sbjct: 35  NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94

Query: 198 QAP 200
             P
Sbjct: 95  GKP 97


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 69/269 (25%), Positives = 94/269 (34%), Gaps = 42/269 (15%)

Query: 7   MDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKP-----EENSAVPALSPAAA 61
           +D    +  P+ ++R   + +   S  E  S P S E  KP       N A PA+  AA 
Sbjct: 132 LDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAM--AAP 189

Query: 62  PPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGAS--------LSPS-FGSTWS 112
              P    ++ +    +PG      P  PPP   P APG            PS F   ++
Sbjct: 190 QLGPGQTTQLPLSESSVPGA-----PHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFT 244

Query: 113 TGTTNAVEDSFFQGITPVNGTMLFQNFPHHV---------NPVFGGTFSPQIGLAQTQHH 163
           T   N   ++  QG          QN P             P      +P  G  Q+Q  
Sbjct: 245 THLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPP 304

Query: 164 QQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTS----- 218
             PPPP PAP  A PA PP+  PP+      +P+    A         H    T+     
Sbjct: 305 PLPPPPPPAPGSAPPALPPEG-PPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANN 363

Query: 219 ------KPSSSSAVAAAAAAAAASSASSS 241
                  PSS+   A    AAA  +   S
Sbjct: 364 PLPPGGDPSSAPGPALLGEAAAPGNGQRS 392



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 58/233 (24%), Positives = 74/233 (31%), Gaps = 50/233 (21%)

Query: 3   DDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPS--TPLSSETPKPEENSAVPALSPAA 60
           D +L    +  P+ +  Q  +  P PE      PS  TP S   P P      P  +P A
Sbjct: 261 DSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPA 320

Query: 61  APPA----------------------------PNGPDKMQMESPLLPGLSFHQPPQQPPP 92
            PP                             PN P      +PL PG     P   P P
Sbjct: 321 LPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPG---GDPSSAPGP 377

Query: 93  P--QEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150
               E AAPG       GS   +       +   Q +  +   +L         P   G 
Sbjct: 378 ALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSG---ETEPFLKG- 433

Query: 151 FSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQ 203
             P  G        +  PPA AP P  P QPP A PP   +    P Q+  +Q
Sbjct: 434 --PPGGAG------EGGPPAQAPPP--PQQPPTA-PPSGLKKYEEPLQSMISQ 475



 Score = 36.6 bits (83), Expect = 0.081
 Identities = 50/207 (24%), Positives = 66/207 (31%), Gaps = 28/207 (13%)

Query: 10   SKTQPQPQQQQRQQQQPQPESSVSEAPSTPL---SSETPKPEENSAVPALSPAAAPPAPN 66
            S   P P Q        Q  S  +   STPL   + +T    ++  +P       PP P 
Sbjct: 1073 SSPDPTPSQNPLSLMMTQM-SKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQ 1131

Query: 67   G---------PDKMQM-----ESPL---LPGLS--FHQPPQQPPPPQEPAAPGASLSPSF 107
            G         P +M +     +SP+   LPG     H+PP    P   P      L P+ 
Sbjct: 1132 GSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNA 1191

Query: 108  GSTWSTGTTNAV-----EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH 162
              T      + +      DS      PV  +     FP  +    G       G      
Sbjct: 1192 QGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGL 1251

Query: 163  HQQPPPPAPAPQPAQPAQPPQAQPPQQ 189
             Q  P     P    P QPP   PPQQ
Sbjct: 1252 QQHYPSGMALPPEDLPNQPPGPMPPQQ 1278



 Score = 33.9 bits (76), Expect = 0.52
 Identities = 48/204 (23%), Positives = 72/204 (35%), Gaps = 33/204 (16%)

Query: 26   PQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGP----DKMQMESPLL--- 78
            P P    S  P  P +  T  P +NS + A     +  AP GP     +M    P L   
Sbjct: 1176 PSPTPLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQP 1235

Query: 79   -------------PGLSFHQPPQQPPPPQE-PAAPGASLSPSFGSTWSTGTTNAVEDSFF 124
                         PGL  H P     PP++ P  P   + P             + D++ 
Sbjct: 1236 HGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQ-QHLMGKAMAGRMGDAYP 1294

Query: 125  QGITPVNGTMLFQ-NFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQ 183
             G+ P   ++L        + P   G   P+  L++    ++P        P    QPP+
Sbjct: 1295 PGVLPGVASVLNDPELSEVIRPTPTGI--PEFDLSRIIPSEKPSSTLQY-FPKSENQPPK 1351

Query: 184  AQPP-------QQRRSPASPSQAP 200
            AQPP       Q   +  +PS+ P
Sbjct: 1352 AQPPNLHLMNLQNMMAEQTPSRPP 1375


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 43/109 (39%), Positives = 51/109 (46%), Gaps = 12/109 (11%)

Query: 141 HHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQ-- 198
           HH +P       P        +  Q PP AP P P  P+QPPQ QPPQQ + P  PS   
Sbjct: 158 HHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQ-QPPQQSQ-PQQPSHPG 215

Query: 199 --------APYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239
                   A  A  +AAAA G    ++  P      AAAAAAAAA+S S
Sbjct: 216 KMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTS 264



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 38/91 (41%), Positives = 44/91 (48%), Gaps = 15/91 (16%)

Query: 158 AQTQHHQQPPPPAPAPQPAQP-------AQPPQA-QPPQQRRSPASPSQAPYAQRSAAAA 209
           A   HH  PP P P P P  P        QPP A QPP     P  PSQ P  Q+    +
Sbjct: 154 AHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPPTAPQPP-----PHLPSQPP--QQPPQQS 206

Query: 210 YGHQPIMTSKPSSSSAVAAAAAAAAASSASS 240
              QP    K   ++AVAAAAAAAAA++  S
Sbjct: 207 QPQQPSHPGKMQEAAAVAAAAAAAAAAAVGS 237



 Score = 34.3 bits (77), Expect = 0.40
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 54  PALSPAAAPPAPNGPDKMQMESPLLPGLSFH---QPPQQPP---PPQEPAAPG 100
           P   P   PP P+       + P  P    H   QPPQQPP    PQ+P+ PG
Sbjct: 163 PQPPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPG 215


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 81/304 (26%), Positives = 111/304 (36%), Gaps = 49/304 (16%)

Query: 8   DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67
           + S T+P P  ++R    P     +    S  LSS        SA P  SPA + P+  G
Sbjct: 205 EHSTTEPSPAARRR----PSAGGGLQRPASRSLSS--------SATPLSSPARSGPSARG 252

Query: 68  PDK--MQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQ 125
             +       P   GL   +PP Q  PP++ AAP  +L P   S  +T + +A       
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPP-QVTPPRKDAAP--ALGPLSSSPLATPSPSAPPSP--- 306

Query: 126 GITPVNGTMLFQNFPH-HVNPVFGGTFSPQIGLAQTQHHQQPPPP-APAPQPAQPAQPPQ 183
                +     Q  P     P    T S      Q  H   P PP +P   P   A P  
Sbjct: 307 -----SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 184 AQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243
           A PP Q  +P SP  +P             P+ T  P + +A+A     A  S   S   
Sbjct: 362 ALPPLQ--APPSPPASPPL----------SPLATPSPQAPNALAVHLLQAPFSPPPS--- 406

Query: 244 THQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAP 303
               V A +S P++P     A   P +A        + VP    P  P   P S +   P
Sbjct: 407 --PPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP----PSPPASPPMSPSATPP 459

Query: 304 PKFP 307
           P+ P
Sbjct: 460 PQAP 463



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 71/243 (29%), Positives = 90/243 (37%), Gaps = 42/243 (17%)

Query: 16  PQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGP---DKMQ 72
           P Q       P  +++ S  PS PLS     P +     AL P  APP+P        + 
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382

Query: 73  MESPLLP-GLSFH--QPPQQPPPP---QEPAAPGAS--LSPSFGSTWSTGTTNAVEDSFF 124
             SP  P  L+ H  Q P  PPP    Q P +P AS  +SPS                  
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS------------------ 424

Query: 125 QGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAP----QPAQPAQ 180
               P          P  V P      SP +  + T   Q PPP A  P    +P   A 
Sbjct: 425 -ATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481

Query: 181 PPQAQPPQQR--RSPAS-PSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASS 237
           P  A PP Q     PAS P QAP+   S +A+    P+ T  P +   +AA       S 
Sbjct: 482 PALATPPLQALPSPPASFPGQAPF---SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538

Query: 238 ASS 240
            +S
Sbjct: 539 PAS 541



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 65/246 (26%), Positives = 84/246 (34%), Gaps = 26/246 (10%)

Query: 34  EAP-STPLSSETPKPEENSAVPALSPAAAPP--APNGPDKMQMESPLLPGLSFHQPPQQP 90
           +AP S P S     P    A P +SP+A PP  AP       ++ P  P  S    P   
Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457

Query: 91  PPPQEP---AAPGASLS---PSFGSTWSTGTTNAVED--SFFQGITPVNGTMLFQNFPHH 142
           PPPQ P   AAP   L+   P      +T    A+    + F G  P + +      P  
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517

Query: 143 VNPVFGGTFSPQIGLAQTQHHQQPPPPA----------PAPQPAQPAQPPQAQPPQQRRS 192
             P      +P + LA       P PPA          P P P      P+         
Sbjct: 518 TPP----PQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 193 PASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAW 252
           P  PS++P +  S     GH    TS P       +     AA+S            AAW
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632

Query: 253 SAPSNP 258
           S    P
Sbjct: 633 SRGPAP 638



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 72/276 (26%), Positives = 108/276 (39%), Gaps = 30/276 (10%)

Query: 55  ALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPG-ASLSPSFGSTWST 113
           A  P +AP A  GP +     P   G     PP +   P   ++PG AS +   G     
Sbjct: 68  ATIPESAPRA--GPTRTSR--PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123

Query: 114 GTTNAVEDSFFQG--ITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQP--PPP 169
           G   + E++  +G        + L        +    GT SP +         +   P P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183

Query: 170 APAPQPAQPAQ-PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAA 228
           AP+ +P  P + P ++       S   PS  P A+R  +A  G Q     +P+S S    
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPS--PAARRRPSAGGGLQ-----RPASRS---L 233

Query: 229 AAAAAAASSASSSWNTHQSVNAAWSAPSNPW-GGLQAGRDPR---------RAVGVGVGV 278
           +++A   SS + S  + +    A + PS P   GLQA R P+          A+G     
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293

Query: 279 GVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTS 314
            +  PSP  P SP   P    + +PP  P +   TS
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 57/229 (24%), Positives = 77/229 (33%), Gaps = 41/229 (17%)

Query: 28  PESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPG------- 80
           P S  +  P +PL++  P+     A P L    +PPA   P       P  PG       
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSG 561

Query: 81  --LSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQN 138
             L+    P  PPPP    +P ++LS    +  S+  T+  E+        + G      
Sbjct: 562 PRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEE--------LRG------ 605

Query: 139 FPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASP-- 196
             +   P  G   SP         H       PAP  A    P    P      P S   
Sbjct: 606 --YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663

Query: 197 ------SQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239
                 ++ P +   A  A    P     P +S   AAA A A ASS S
Sbjct: 664 LCTIYETEGPESATPAPGALDPGP----SPGTSGGKAAAGAGAGASSRS 708



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 67/304 (22%), Positives = 105/304 (34%), Gaps = 44/304 (14%)

Query: 26  PQPESSVSEAPST--PLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSF 83
           P+P  S    P T  P  S +   E ++  P+ +    P A  G     ++ P    LS 
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-----LQRPASRSLSS 235

Query: 84  HQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHV 143
              P   P    P+A G   +P+  S          +    Q + P   T   ++    +
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQ--------PKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 144 NPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQ----PAQPAQPP------------QAQPP 187
            P+     +       T     PP P+  P     P+ PA PP            QA   
Sbjct: 288 GPLSSSPLA-------TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340

Query: 188 QQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQS 247
                P SP   P  Q   A A    P + + PS  ++   +  A  +  A ++   H  
Sbjct: 341 FLPSPPLSPLATPPPQAPPALAL---PPLQAPPSPPASPPLSPLATPSPQAPNALAVH-L 396

Query: 248 VNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFP 307
           + A +S P +P   +QA   P  +  V         +P +  +P  +   S   +PP  P
Sbjct: 397 LQAPFSPPPSP--PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454

Query: 308 RAAP 311
            A P
Sbjct: 455 SATP 458



 Score = 37.0 bits (84), Expect = 0.062
 Identities = 72/301 (23%), Positives = 105/301 (34%), Gaps = 32/301 (10%)

Query: 31  SVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNGPDKMQMESPLLPGLSFHQPPQQP 90
           S  E  +   ++E PK    SA      +   P P  P           G     P   P
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSG--PTPGTPSPAMARRSRAAGTEVGLPRPAP 185

Query: 91  PPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGT 150
                P   G   S S  S  ST      E S      P  G  L +     ++      
Sbjct: 186 SARPRPPTEGPRKSVSSASEHST-----TEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240

Query: 151 FSPQIGLAQTQHHQQPP--PPAPAPQPAQPAQPPQAQPPQQRRSPA--SPSQAPYAQRSA 206
            SP       +   + P  P  P P+  Q  +PPQ  PP++  +PA    S +P A  S 
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300

Query: 207 AAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGR 266
           +A     P  ++ PS  +  +  A   + ++ S    T Q+ ++    PS P   L A  
Sbjct: 301 SA----PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS--FLPSPPLSPL-ATP 353

Query: 267 DPRRAVGVGVGVGVGVPSP--LNPISPL--KKPFSSNVIA----------PPKFPRAAPL 312
            P+    + +      PSP    P+SPL    P + N +A          PP  P  AP 
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413

Query: 313 T 313
           +
Sbjct: 414 S 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,659,206
Number of Sequences: 37866
Number of extensions: 2207721
Number of successful extensions: 52616
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 745
Number of HSP's successfully gapped in prelim test: 1656
Number of HSP's that attempted gapping in prelim test: 21142
Number of HSP's gapped (non-prelim): 17789
length of query: 698
length of database: 18,247,518
effective HSP length: 109
effective length of query: 589
effective length of database: 14,120,124
effective search space: 8316753036
effective search space used: 8316753036
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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