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Search of human proteins with 5032169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032169 telomeric repeat binding factor 2 [Homo sapiens]
(500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032169 telomeric repeat binding factor 2 [Homo sapiens] 992 0.0
gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s... 131 2e-30
gi|189409140 telomeric repeat binding factor 1 isoform 2 [Homo s... 95 2e-19
gi|169212925 PREDICTED: similar to telomeric repeat binding fact... 94 4e-19
gi|89044853 PREDICTED: similar to telomeric repeat binding facto... 91 2e-18
gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Ho... 46 9e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 44 3e-04
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 43 8e-04
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 43 8e-04
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 42 0.001
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 40 0.004
gi|4505293 MYB-related protein B [Homo sapiens] 40 0.006
gi|239747124 PREDICTED: hypothetical protein XP_002343917 [Homo ... 39 0.008
gi|24431975 hypothetical protein LOC26148 [Homo sapiens] 39 0.011
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 39 0.014
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 39 0.014
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 39 0.014
gi|157738619 smoothelin-like 1 [Homo sapiens] 39 0.014
gi|104526627 triadin [Homo sapiens] 38 0.019
gi|153792633 hypothetical protein LOC26049 [Homo sapiens] 38 0.025
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 37 0.032
gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 37 0.032
gi|222537714 taxilin beta [Homo sapiens] 37 0.042
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 37 0.042
gi|213385278 TNF receptor-associated factor 3 interacting protei... 37 0.042
gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens] 37 0.042
gi|20070262 TNF receptor-associated factor 3 interacting protein... 37 0.055
gi|51173735 ras responsive element binding protein 1 isoform 2 [... 37 0.055
gi|51173737 ras responsive element binding protein 1 isoform 1 [... 37 0.055
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 37 0.055
>gi|5032169 telomeric repeat binding factor 2 [Homo sapiens]
Length = 500
Score = 992 bits (2564), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFY 60
MAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFY
Sbjct: 1 MAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFY 60
Query: 61 FHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSF 120
FHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSF
Sbjct: 61 FHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSF 120
Query: 121 DMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKK 180
DMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKK
Sbjct: 121 DMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKK 180
Query: 181 HMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMA 240
HMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMA
Sbjct: 181 HMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMA 240
Query: 241 KKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQD 300
KKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQD
Sbjct: 241 KKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQD 300
Query: 301 SEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTIS 360
SEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTIS
Sbjct: 301 SEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTIS 360
Query: 361 RLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEK 420
RLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEK
Sbjct: 361 RLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEK 420
Query: 421 ETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFV 480
ETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFV
Sbjct: 421 ETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFV 480
Query: 481 NRTAVMIKDRWRTMKRLGMN 500
NRTAVMIKDRWRTMKRLGMN
Sbjct: 481 NRTAVMIKDRWRTMKRLGMN 500
>gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo
sapiens]
Length = 439
Score = 131 bits (329), Expect = 2e-30
Identities = 120/468 (25%), Positives = 201/468 (42%), Gaps = 108/468 (23%)
Query: 40 ERGAGEARLEEAVNR-WVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVS 98
E AG EAV W+L F RAFR R DFR+ R+ +A++
Sbjct: 61 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL 120
Query: 99 RLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVK 158
R + + Q L+RI G+ LD F+ + +TPLESA+ + I+ E + + E + L+K
Sbjct: 121 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEH---DKLHEEIQNLIK 177
Query: 159 EAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQ 218
A+ +C++N F++A ++ ++ + ++ LL II +K+ H Q+FSY
Sbjct: 178 IQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMM 237
Query: 219 QKMLRFLESHLDD-AEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLR 277
+K+ ++ L + + +L+ A K ++S+ + T ++ +P+ VE
Sbjct: 238 EKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQD--KPSGNDVE----------- 284
Query: 278 NPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENE 337
M +A T D ++A E
Sbjct: 285 --------METEANLDTRKSVSDKQSAV------------------------------TE 306
Query: 338 SSAPADGEGGSELQPKNKRMTISRL---VLEEDSQSTEPSAGLNSS----QEAASAPPSK 390
SS EG L +K + +S+L ++D E G S +E+ A S+
Sbjct: 307 SS-----EGTVSLLRSHKNLFLSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESR 361
Query: 391 -PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQK 449
P +QP+ EK + +++ W+
Sbjct: 362 IPVSKSQPVTPEK------------HRARKRQAWL------------------------- 384
Query: 450 WTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRL 497
W EE + +++GV+KYGEGNW+ I +Y F NRT+VM+KDRWRTMK+L
Sbjct: 385 W--EEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKL 430
>gi|189409140 telomeric repeat binding factor 1 isoform 2 [Homo
sapiens]
Length = 419
Score = 94.7 bits (234), Expect = 2e-19
Identities = 64/229 (27%), Positives = 116/229 (50%), Gaps = 7/229 (3%)
Query: 40 ERGAGEARLEEAVNR-WVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVS 98
E AG EAV W+L F RAFR R DFR+ R+ +A++
Sbjct: 61 EEDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHGLSSLTACQL 120
Query: 99 RLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVK 158
R + + Q L+RI G+ LD F+ + +TPLESA+ + I+ E + + E + L+K
Sbjct: 121 RTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSIEKEH---DKLHEEIQNLIK 177
Query: 159 EAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQ 218
A+ +C++N F++A ++ ++ + ++ LL II +K+ H Q+FSY
Sbjct: 178 IQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFKSKLLMIISQKDTFHSFFQHFSYNHMM 237
Query: 219 QKMLRFLESHLDD-AEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVE 266
+K+ ++ L + + +L+ A K ++S+ + T ++ +P+ VE
Sbjct: 238 EKIKSYVNYVLSEKSSTFLMKAAAKVVESKRTRTITSQD--KPSGNDVE 284
Score = 72.8 bits (177), Expect = 7e-13
Identities = 31/52 (59%), Positives = 42/52 (80%)
Query: 446 KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRL 497
K+Q W EE + +++GV+KYGEGNW+ I +Y F NRT+VM+KDRWRTMK+L
Sbjct: 359 KRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKL 410
>gi|169212925 PREDICTED: similar to telomeric repeat binding factor
(NIMA-interacting) 1 [Homo sapiens]
Length = 405
Score = 93.6 bits (231), Expect = 4e-19
Identities = 57/213 (26%), Positives = 109/213 (51%), Gaps = 4/213 (1%)
Query: 45 EARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVM 104
EA E W+L+F RAFR R DF + R+ +A++ R + +
Sbjct: 53 EAEAEAVAAGWMLEFLCFSLCRAFRDGRSEDFCRTRNSAEAIIHGLSSLTAYQLRTIYIC 112
Query: 105 QCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVII 164
Q L+RI G+ LD F+ + +TPLESA+ + I+ + + + E + L+K A+ +
Sbjct: 113 QFLTRIAAGKTLDAQFENDERITPLESALIIWGSIEKKH---DKLQEEIQNLIKIQAIAV 169
Query: 165 CIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRF 224
C++N F++A ++ ++ + L++ LL II +K+ H Q+FSY +K+ +
Sbjct: 170 CMENGNFKEAEEVFERLFGDPNSYMPLKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSY 229
Query: 225 LESHLDD-AEPYLLTMAKKALKSESAASSTGKE 256
+ L + + +L+ A K ++S+ + T ++
Sbjct: 230 VNYVLSEKSSTFLMKAAAKVVESKRTRTITSQD 262
Score = 67.4 bits (163), Expect = 3e-11
Identities = 28/52 (53%), Positives = 40/52 (76%)
Query: 446 KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRL 497
K+Q W EE + +++G++KYGEGNW+ I +Y F NRT+V +KDRWRT K+L
Sbjct: 345 KRQAWLQEEDKNLRSGMRKYGEGNWSKILLHYKFNNRTSVTLKDRWRTTKKL 396
>gi|89044853 PREDICTED: similar to telomeric repeat binding factor
(NIMA-interacting) 1 [Homo sapiens]
Length = 405
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/213 (26%), Positives = 108/213 (50%), Gaps = 4/213 (1%)
Query: 45 EARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVM 104
EA E W+L+F RAF R DF + R+ +A++ R + +
Sbjct: 53 EAEAEAVAAGWMLEFLCFSLCRAFPDGRSEDFCRTRNSAEAIIHGLSSLTAYQLRTIYIC 112
Query: 105 QCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVII 164
Q L+RI G+ LD F+ + +TPLESA+ + I+ + + + E + L+K A+ +
Sbjct: 113 QFLTRIAAGKTLDAQFENDERITPLESALIIWGSIEKKH---DKLQEEIQNLIKIQAIAV 169
Query: 165 CIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRF 224
C++N F++A ++ ++ + L++ LL II +K+ H Q+FSY +K+ +
Sbjct: 170 CMENGNFKEAEEVFERLFGDPNSYMPLKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSY 229
Query: 225 LESHLDD-AEPYLLTMAKKALKSESAASSTGKE 256
+ L + + +L+ A K ++S+ + T ++
Sbjct: 230 VNYVLSEKSSTFLMKAAAKVVESKRTRTITSQD 262
Score = 68.6 bits (166), Expect = 1e-11
Identities = 29/52 (55%), Positives = 40/52 (76%)
Query: 446 KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRL 497
K+Q W EE + +++GV+KYGEGNW+ I +Y F NRT+V +KDRWRT K+L
Sbjct: 345 KRQAWLQEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVTLKDRWRTTKKL 396
>gi|28559071 DNA cytosine methyltransferase 3 alpha isoform c [Homo
sapiens]
Length = 166
Score = 45.8 bits (107), Expect = 9e-05
Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 22/151 (14%)
Query: 247 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAF--KTLSGAQDSEAA 304
E GKE++Q P + P R+ ++PP G A K+ S AQDS A+
Sbjct: 27 EEQEEPRGKEERQE-PSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGAS 85
Query: 305 FAKLDQKDLVLPTQALPASPALKNKRPRKDEN------ESSAPADGEGGSELQPKNKRMT 358
+ LP K P+ +E + APA+GEG +E P+ R
Sbjct: 86 -------------ELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAV 132
Query: 359 ISRLVLEEDSQSTEPSAGLNSSQEAASAPPS 389
+ ++ + AG +S+ AAS+ P+
Sbjct: 133 ENGCCTPKEGRGAPAEAGESSAPGAASSGPT 163
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 43.9 bits (102), Expect = 3e-04
Identities = 49/211 (23%), Positives = 81/211 (38%), Gaps = 38/211 (18%)
Query: 239 MAKKALKSESAASST-GKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSG 297
+AKKA K S++ S E+++ GP K PA+++ PP KAA K
Sbjct: 74 VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG-------KAAAKASES 126
Query: 298 AQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRM 357
+ E++ ++ P Q A K P K S + +D E PKN++
Sbjct: 127 SSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE-PPKNQKP 185
Query: 358 TISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGV 417
I+ + ++ ++ APP P PK+ GK SS+
Sbjct: 186 KITPVTVKAQTK----------------APPK---------PARAAPKIANGKAASSSSS 220
Query: 418 EEKETWVEEDELFQVQAAPDEDSTTNITKKQ 448
+ ++ E + A P + + KKQ
Sbjct: 221 SSSSSSSDDSEEEKAAATPKK----TVPKKQ 247
Score = 38.9 bits (89), Expect = 0.011
Identities = 51/237 (21%), Positives = 85/237 (35%), Gaps = 47/237 (19%)
Query: 240 AKKALKSESAASSTGKEDKQPAP----GPVEKPPREPARQLRNP----------PTTIGM 285
AKKA +S S +S + + AP G + +PA ++P P G
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 286 MTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGE 345
L + S ++S ++ + +K + A AL + + + +D +
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 346 GGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAAS-APPSKPTVLNQPLPGEKNP 404
S EE+ + T SA Q+ A A PSKP
Sbjct: 475 SSSS---------------EEEEEKTSKSAVKKKPQKVAGGAAPSKPA------------ 507
Query: 405 KVPKGKWNSSNGVEEKETWVEEDELFQVQA-----APDEDSTTNITKKQKWTVEESE 456
KGK SSN ++ EE+E + + AP + T+ +T + + SE
Sbjct: 508 SAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSE 564
Score = 32.7 bits (73), Expect = 0.79
Identities = 45/209 (21%), Positives = 78/209 (37%), Gaps = 29/209 (13%)
Query: 242 KALKSESAASSTGKEDKQP-------APGPVEKPPREPARQLRNPPTTIG--MMTLKAAF 292
K KS + S + ED+ P P V+ + P + R P + ++
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSS 221
Query: 293 KTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQP 352
+ S + DSE A K V Q + +P P + +SS+ D E
Sbjct: 222 SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR---KSSSSEDSSSDEE--- 275
Query: 353 KNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWN 412
EE + + G SS SAPP K ++ Q P +K + + +
Sbjct: 276 ------------EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQ--PPKKAVEKQQPVES 321
Query: 413 SSNGVEEKETWVEEDELFQVQAAPDEDST 441
S + +E ++ EE++ +A + +T
Sbjct: 322 SEDSSDESDSSSEEEKKPPTKAVVSKATT 350
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 42.7 bits (99), Expect = 8e-04
Identities = 49/210 (23%), Positives = 84/210 (40%), Gaps = 17/210 (8%)
Query: 230 DDAEPYLLTMAKKALKSESAASSTGKE--DKQPAPG--PVEKP---PREPARQLRNPPTT 282
D A+P + MA+ A S S++SS+ + K+P G P EKP PR + PP++
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSS 300
Query: 283 IGM------MTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDEN 336
+ + +K A+ E + +++ L + +R R D
Sbjct: 301 SSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRG 360
Query: 337 ESSAPADGEGGSEL----QPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPT 392
E+ + G G EL +P KR R S +EP A L + ++ P +
Sbjct: 361 EAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSS 420
Query: 393 VLNQPLPGEKNPKVPKGKWNSSNGVEEKET 422
PG+K +V + + V+ + T
Sbjct: 421 TEPARKPGQKEKRVRPEEKQQAKPVKVERT 450
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 42.7 bits (99), Expect = 8e-04
Identities = 49/210 (23%), Positives = 84/210 (40%), Gaps = 17/210 (8%)
Query: 230 DDAEPYLLTMAKKALKSESAASSTGKE--DKQPAPG--PVEKP---PREPARQLRNPPTT 282
D A+P + MA+ A S S++SS+ + K+P G P EKP PR + PP++
Sbjct: 241 DGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSS 300
Query: 283 IGM------MTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDEN 336
+ + +K A+ E + +++ L + +R R D
Sbjct: 301 SSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRG 360
Query: 337 ESSAPADGEGGSEL----QPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPT 392
E+ + G G EL +P KR R S +EP A L + ++ P +
Sbjct: 361 EAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSS 420
Query: 393 VLNQPLPGEKNPKVPKGKWNSSNGVEEKET 422
PG+K +V + + V+ + T
Sbjct: 421 TEPARKPGQKEKRVRPEEKQQAKPVKVERT 450
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Query: 299 QDSEAAFAKLDQKDL---VLPTQALPASPALKNKRPRKD-ENESSAPADGEGGSELQPKN 354
++ E+A + D++ L + ++ + K P K E E P E P
Sbjct: 876 KNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPV---ANRECDPAE 932
Query: 355 KRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSS 414
+ +++LE D+Q EP G + AS+P +P V LPG + VP G +
Sbjct: 933 LEEKVPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGG 992
Query: 415 NG 416
G
Sbjct: 993 RG 994
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/220 (25%), Positives = 80/220 (36%), Gaps = 29/220 (13%)
Query: 215 ETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTG-KEDKQPAPGPVEKPPREPA 273
+T QQK L H DA T AL+ E + K D P+ P E A
Sbjct: 1304 DTSQQKSAGLLMVHTVDA-----TKLDNALQEEDEKAEVEMKPDSSPSEVPEGVSETEGA 1358
Query: 274 RQLRNPP--TTIGMMTLKAAFKTLSGA----QDSEAAFAKLDQKDLVLPTQALPASPALK 327
Q+ P TT+ T+ A + A +D + + T+ LP
Sbjct: 1359 LQISAAPEPTTVPGRTIVAVGSMEEAVILPFRIPPPPLASVDLDEDFIFTEPLPPPLEFA 1418
Query: 328 NKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAP 387
N D+ +S PA +S LV ++ S T S LNSSQ SA
Sbjct: 1419 NSFDIPDDRAASVPA----------------LSDLVKQKKSD-TPQSPSLNSSQPTNSAD 1461
Query: 388 PSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEED 427
KP L+ LP P + +G+EE ++ D
Sbjct: 1462 SKKPASLSNCLPASFLPPPESFDAVADSGIEEVDSRSSSD 1501
>gi|4505293 MYB-related protein B [Homo sapiens]
Length = 700
Score = 39.7 bits (91), Expect = 0.006
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 427 DELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVM 486
DEL D + K KWT EE E ++A V+++G+ +W ++ ++P NRT
Sbjct: 11 DELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFP--NRTDQQ 68
Query: 487 IKDRW 491
+ RW
Sbjct: 69 CQYRW 73
Score = 30.8 bits (68), Expect = 3.0
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 447 KQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRW 491
K WT EE + V V+KYG W I+K+ R ++RW
Sbjct: 83 KGPWTKEEDQKVIELVKKYGTKQWTLIAKH--LKGRLGKQCRERW 125
>gi|239747124 PREDICTED: hypothetical protein XP_002343917 [Homo
sapiens]
Length = 130
Score = 39.3 bits (90), Expect = 0.008
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 46 ARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQ 105
A+ E W+L F RAFR R DF +IR+ +A++ R + + Q
Sbjct: 52 AKAEAVAAGWMLDFLRFSLCRAFRDGRSEDFCRIRNRAEAIIHGLSSLTAYQLRTIYICQ 111
Query: 106 CLSRIEEGENLDCSFD 121
L+RI G+ LD F+
Sbjct: 112 FLTRIAAGKTLDAQFE 127
>gi|24431975 hypothetical protein LOC26148 [Homo sapiens]
Length = 1247
Score = 38.9 bits (89), Expect = 0.011
Identities = 87/427 (20%), Positives = 163/427 (38%), Gaps = 88/427 (20%)
Query: 112 EGENLD--CSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSR-KLVKEAAVIICIKN 168
EGE+ D C + + T ++S L+ K EA R +L ++ C++N
Sbjct: 464 EGEDGDVKCLSEKDTYDTSIDSLEENLDKKKKGKKFPEASDRCLRSQLSDSSSADRCLRN 523
Query: 169 KEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKML--RFLE 226
+ + +S L+ + K+P+ + R K HP T + +L F
Sbjct: 524 QSSDSSSACLEIKVPKNPSAK----------RSKKEGHP------GGTTPKGLLPDSFHT 567
Query: 227 SHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQL---RNPPTTI 283
L+D E + +E G +Q ++K +E ++ R+P TT
Sbjct: 568 ETLEDTEKPSVNERPSEKDAEQEGEGGGIITRQTLKNMLDKEVKELRGEIFPSRDPITTA 627
Query: 284 GMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPAD 343
G + L G + +K+D+K+ +P++++ A K + E P
Sbjct: 628 G--------QPLPGERLEIYVQSKMDEKNAHIPSESI----ACKRDPEQAKEEPGHIPTQ 675
Query: 344 --GEGGSELQPKNKRMTISRLVLEEDSQSTEP--SAGLNS--SQEAASAPPSKP------ 391
E +E+ +N + ++D +S P S GL+S S +AA AP S P
Sbjct: 676 HVEEAVNEVDNENTQ--------QKDDESDAPCSSLGLSSSGSGDAARAPKSVPRPKRLT 727
Query: 392 ------------------TVLNQPLPGEKNPKVPKGKWNSSNG----VEEKETWVEEDEL 429
V ++ + NP +PK S +G ++ +T V+E
Sbjct: 728 SSTYNLRHAHSLGSLDASKVTSEKEAAQVNPIMPKENGASESGDPLDEDDVDTVVDEQPK 787
Query: 430 FQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKD 489
F A +E+ ++ + W++ ++K G+ P + +K+
Sbjct: 788 FMEWCAEEENQELIANFNAQYMKVQKGWIQ--LEKEGQPT--------PRARNKSDKLKE 837
Query: 490 RWRTMKR 496
W++ KR
Sbjct: 838 IWKSKKR 844
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 38.5 bits (88), Expect = 0.014
Identities = 32/151 (21%), Positives = 64/151 (42%), Gaps = 10/151 (6%)
Query: 330 RPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAA----- 384
RP ++E D +E + + K+ + E+ ++T+ ++ + E
Sbjct: 507 RPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQ 566
Query: 385 SAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNI 444
+ P + T +Q G + ++ + N + E+ + P+ ST +
Sbjct: 567 ATPRGRKTANSQ---GRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPV 623
Query: 445 TKKQKWTVEESEWVKAGVQKYGEGNWAAISK 475
+ +WT EE E K G+ ++G NWAAI+K
Sbjct: 624 -ETSRWTEEEMEVAKKGLVEHGR-NWAAIAK 652
>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/138 (25%), Positives = 54/138 (39%), Gaps = 22/138 (15%)
Query: 247 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAF--KTLSGAQDSEAA 304
E GKE++Q P + P R+ ++PP G A K+ S AQDS A+
Sbjct: 27 EEQEEPRGKEERQE-PSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGAS 85
Query: 305 FAKLDQKDLVLPTQALPASPALKNKRPRKDEN------ESSAPADGEGGSELQPKNKRMT 358
+ LP K P+ +E + APA+GEG +E P+ R
Sbjct: 86 -------------ELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAV 132
Query: 359 ISRLVLEEDSQSTEPSAG 376
+ ++ + AG
Sbjct: 133 ENGCCTPKEGRGAPAEAG 150
>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/138 (25%), Positives = 54/138 (39%), Gaps = 22/138 (15%)
Query: 247 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAF--KTLSGAQDSEAA 304
E GKE++Q P + P R+ ++PP G A K+ S AQDS A+
Sbjct: 27 EEQEEPRGKEERQE-PSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPSMAQDSGAS 85
Query: 305 FAKLDQKDLVLPTQALPASPALKNKRPRKDEN------ESSAPADGEGGSELQPKNKRMT 358
+ LP K P+ +E + APA+GEG +E P+ R
Sbjct: 86 -------------ELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAV 132
Query: 359 ISRLVLEEDSQSTEPSAG 376
+ ++ + AG
Sbjct: 133 ENGCCTPKEGRGAPAEAG 150
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 38.5 bits (88), Expect = 0.014
Identities = 52/251 (20%), Positives = 90/251 (35%), Gaps = 32/251 (12%)
Query: 246 SESAASSTGKEDKQPAP---GPVEKPPREPARQLRNPPTTIGMMTLKA-AFKTLSGAQDS 301
+E + GK + P G EK P E G+ +K + + G +D+
Sbjct: 49 AEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDA 108
Query: 302 EAAFAKLD--QKDLVLPTQALPASPALKNKRPRKDENESSA-----------PADGEGGS 348
EA K D +++ + +Q + P++ E + S A E G
Sbjct: 109 EAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQ 168
Query: 349 ELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEK------ 402
+ ++ + +EE+ T +E ++ P K T +K
Sbjct: 169 KADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDE 228
Query: 403 ---NPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVK 459
PK P GK + +G +E+ EE E + +A P S ++Q+ VE+
Sbjct: 229 AKAEPKEPDGKEEAKHGAKEEADAKEEAEDAE-EAEPGSPS-----EEQEQDVEKEPEGG 282
Query: 460 AGVQKYGEGNW 470
AGV W
Sbjct: 283 AGVIPSSPEEW 293
Score = 33.1 bits (74), Expect = 0.60
Identities = 48/182 (26%), Positives = 74/182 (40%), Gaps = 27/182 (14%)
Query: 242 KALKSESAASSTGKED----KQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSG 297
KA E A + +E+ K+ + P EK E A+ + KA K G
Sbjct: 181 KATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKA--ESQKAVVEDEAKAEPKEPDG 238
Query: 298 AQDS-----EAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSA---PADGEGGSE 349
+++ E A AK + +D +A P SP+ + ++ + E E A P+ E E
Sbjct: 239 KEEAKHGAKEEADAKEEAEDA---EEAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPE 295
Query: 350 LQPKNKRMTISRLVLEED---SQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKV 406
P + +S L D S T PSA +S + +PP P+ GEK K
Sbjct: 296 -SPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPS------SGEKKEKA 348
Query: 407 PK 408
P+
Sbjct: 349 PE 350
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 38.1 bits (87), Expect = 0.019
Identities = 65/292 (22%), Positives = 118/292 (40%), Gaps = 62/292 (21%)
Query: 233 EPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAF 292
+P T+AK+ K+++A S K K+ G EK + A+ +K
Sbjct: 195 KPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAK-------------VKEVQ 241
Query: 293 KTLSGAQDSE----AAFAKLDQKDLV--------------------------LPTQAL-- 320
KT S ++ E AA +K +QKD LPT+
Sbjct: 242 KTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASR 301
Query: 321 --PASPALKNK--RPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAG 376
PASPAL+ K +K E + ++ + +++ K+++ T + +E +++E G
Sbjct: 302 PTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQG 361
Query: 377 L--NSSQEAA--------SAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEE 426
++Q AA S KP + QP G+K K K + + +E ++
Sbjct: 362 TVKIAAQAAAKKDEKKEDSKKTKKPAEVEQP-KGKKQEKKEKHVEPAKSPKKEHSVPSDK 420
Query: 427 DELFQVQAAPDEDSTTNITKKQKWTVEE--SEWVKAGVQKYGEGNWAAISKN 476
+ + A +E +I K EE ++ V+ ++K G ++I K+
Sbjct: 421 QVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKD 472
>gi|153792633 hypothetical protein LOC26049 [Homo sapiens]
Length = 670
Score = 37.7 bits (86), Expect = 0.025
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 18/115 (15%)
Query: 327 KNKRPRKDENESSAPADGEGGSELQPKN-----KRMTISRLVLEEDSQSTEPSAGL---- 377
++ RP + DGE SEL+P N + S + EEDS S L
Sbjct: 401 RDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQP 460
Query: 378 -NSSQEAASAPP-----SKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEE 426
NSS+++ + P SKP ++ P +K P++P + G +++ +EE
Sbjct: 461 FNSSEDSTNLVPLVVESSKPPEVDAP---DKTPRIPDSEMLMDEGTSDEKGHMEE 512
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 37.4 bits (85), Expect = 0.032
Identities = 50/234 (21%), Positives = 84/234 (35%), Gaps = 20/234 (8%)
Query: 272 PARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAA----FAKLDQKDLVLPTQALPASPALK 327
P + PP I M ++ KT + +E + + +K PTQ +P + ALK
Sbjct: 552 PMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRPTQKIPETKALK 611
Query: 328 NKRPRKDENESSAPADGEGGSELQPKNK---------RMTISRLVLEEDSQSTEPSAGLN 378
+K E S + +++ +T S +E + +P G N
Sbjct: 612 HKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRN 671
Query: 379 SSQEAASAPPSKPTVLNQPLPGEKNPK------VPKGKWNSSNGVEEKETWVEEDELFQV 432
+ AP +P N PL EK VPK + ++ +++E Q+
Sbjct: 672 KATAHKPAPRKEPRP-NIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQI 730
Query: 433 QAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVM 486
+ P + T K K S + + G N +IS P + VM
Sbjct: 731 KVLPPCIISGGNTAKSKEICGASLTLSTLMSSSGSNNNLSISNEEPTFSPIPVM 784
>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
190kDa [Homo sapiens]
Length = 1469
Score = 37.4 bits (85), Expect = 0.032
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 446 KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTM 494
KK +W ++E E + ++KYG G+WA I+ P +R+ +W+ M
Sbjct: 452 KKGRWNLKEEEQLIELIEKYGVGHWAKIASELP--HRSGSQCLSKWKIM 498
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 37.0 bits (84), Expect = 0.042
Identities = 62/276 (22%), Positives = 108/276 (39%), Gaps = 32/276 (11%)
Query: 138 MIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRND--- 194
+++ + TL E + + ++ + +E +K +K +KK + KD T K R +
Sbjct: 355 VLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKK-LEKDTATWKARFENCN 413
Query: 195 --LLNIIREKNLAHPVIQNFSYETFQQKMLRF--LESHLDDAEPYLLTMAKKALKSESAA 250
LL++I EK L YE F K+ R L L + L + A SE
Sbjct: 414 KALLDMIEEKALRAK-----EYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDD 468
Query: 251 SSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQ 310
S D++P V A ++ + T + L AF + + + +K Q
Sbjct: 469 QSQHNSDEEPESN-VSVDQEIDAEEVNSVQTAV--KNLATAFMIIHHPESTPHQ-SKETQ 524
Query: 311 KDLVLPTQALPASPALKNKRPRKDENESSAP-------ADGEGGSELQPKNKRMTISRLV 363
++ ++ A+ + P +S +P A+ EGGS+ +P +K S
Sbjct: 525 PEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASN-SPAG 583
Query: 364 LEEDSQSTEPSAGLNSSQ-------EAASAPPSKPT 392
L ++Q G + Q EA+ P PT
Sbjct: 584 LGAETQCEGLPVGAQADQASWKPEAEASGQAPQAPT 619
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 37.0 bits (84), Expect = 0.042
Identities = 56/294 (19%), Positives = 105/294 (35%), Gaps = 20/294 (6%)
Query: 125 ELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSK 184
E T L S++ V + +K E E R +E KNK+ K +K+
Sbjct: 511 EKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKD-----KNKDKSKEKDKVKEKEKD 565
Query: 185 DPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKML-------RFLESHLDDAEPYLL 237
T ++ + ++E+ + +E K+ + E H D +
Sbjct: 566 KETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREK 625
Query: 238 TMAKKALKSESAASSTGKEDKQPAPG-PVEKPPREPARQLRNPPTTIGMMTLKAAFKTLS 296
K + + G+EDK AP P+ PP+E A L +P T + + + +
Sbjct: 626 GKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVL 685
Query: 297 GA---QDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPK 353
++ E K +KD + K K+ ++ E E E E + K
Sbjct: 686 PEKLFEEKEKVKEKEKKKD---KKEKKKKKEKEKEKKEKEREKEKREREKREKEKE-KHK 741
Query: 354 NKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVP 407
++++ + + L + + + Q+ P +P P + PK P
Sbjct: 742 HEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTP 795
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 37.0 bits (84), Expect = 0.042
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 10/145 (6%)
Query: 315 LPTQALPASPALKNKRPRKD--ENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTE 372
+ T+A + +KR K+ E +S++ A+G+ G Q K++ V E E
Sbjct: 332 ISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSE-------VPETPEIPNE 384
Query: 373 PSAGLNSSQEAASAPPSKPTVLNQP-LPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQ 431
S+ + SA P+ P V Q + + + GK S+ E + EED+ F
Sbjct: 385 LSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFV 444
Query: 432 VQAAPDEDSTTNITKKQKWTVEESE 456
V+AAP + I +EE E
Sbjct: 445 VEAAPQLSEMSEIEMVTAVELEEEE 469
>gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens]
Length = 413
Score = 37.0 bits (84), Expect = 0.042
Identities = 61/274 (22%), Positives = 107/274 (39%), Gaps = 38/274 (13%)
Query: 97 VSRLLRVMQCLSRI-EEGENLDCSFDMEAELTPL--ESAINVLEMIKTEFTLTEAVVESS 153
++ L Q S I +G +L ME EL + E+ LE+ +TE + A+ E
Sbjct: 134 IADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEIL 193
Query: 154 RKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIR-----EKNLAHPV 208
++ K ++ + + E +KI K+ + + ++L + L +R E
Sbjct: 194 TQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRL--ETLQSVRPCFMDEYEKTEEE 251
Query: 209 IQNFSYETFQQKM--LRFLESHLDD-----------AEPYLLTMAKKALKSESAASSTGK 255
+Q Y+T+ +K L +LE L+D A+ L + K + E +G
Sbjct: 252 LQK-QYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGS 310
Query: 256 EDKQPAP--GPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSG------------AQDS 301
D E R+L P T + M+ K + G +++S
Sbjct: 311 NDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEES 370
Query: 302 EAAFAKLDQKDLVLPTQALPASPALKNKRPRKDE 335
E D +D L +++ SP N+R RK E
Sbjct: 371 EIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSE 404
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 36.6 bits (83), Expect = 0.055
Identities = 47/221 (21%), Positives = 89/221 (40%), Gaps = 25/221 (11%)
Query: 244 LKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEA 303
+ + ++ S T K K+ + VE + I +L + ++ + E
Sbjct: 332 ISTRASKSLTTKTSKRRSKNSVEGRKED----------NISAKSLDSIVSGINNEPNQET 381
Query: 304 AFAKLDQKDLVLPTQALP----ASPALKNKRPR---KDENESSAPADGEGGSELQPKNKR 356
+++ K+ + + ++ AS +N +P K + +S++ A+G+ G Q K++
Sbjct: 382 TTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSE- 440
Query: 357 MTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQP-LPGEKNPKVPKGKWNSSN 415
V E E S+ + SA P+ P V Q + + + GK S+
Sbjct: 441 ------VPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNV 494
Query: 416 GVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESE 456
E + EED+ F V+AAP + I +EE E
Sbjct: 495 ITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEE 535
>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
sapiens]
Length = 1687
Score = 36.6 bits (83), Expect = 0.055
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 251 SSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQ 310
+ST +E QPAP EKPP PA + + P K A +T G D E+A K
Sbjct: 1428 ASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEET-EGPSDGESAAEKRSS 1486
Query: 311 K---DLVLPTQALPASPALKNKRPRK 333
+ D P P S A K + +K
Sbjct: 1487 EKSDDDKKPKTDSPKSVASKADKRKK 1512
Score = 32.0 bits (71), Expect = 1.3
Identities = 41/184 (22%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 246 SESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA----QDS 301
S +++ T + K PGP A ++G KAA A ++S
Sbjct: 1073 SSVSSAPTLLKTKVADPGPASTGSNTTASD------SLGGSVPKAATTATPAATTSPKES 1126
Query: 302 EAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISR 361
A + PT+ PA + K R R S P GG +L + +I +
Sbjct: 1127 SEPPAPASSPEAASPTEQGPAGTSKKRGRKR---GMRSRPRANSGGVDLDSSGEFASIEK 1183
Query: 362 LVLEEDSQSTEP---SAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVE 418
++ D+ P +A N+ E A AP ++ K+ + K NS
Sbjct: 1184 MLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCL 1243
Query: 419 EKET 422
+K T
Sbjct: 1244 QKIT 1247
>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
sapiens]
Length = 1742
Score = 36.6 bits (83), Expect = 0.055
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 251 SSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQ 310
+ST +E QPAP EKPP PA + + P K A +T G D E+A K
Sbjct: 1483 ASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEET-EGPSDGESAAEKRSS 1541
Query: 311 K---DLVLPTQALPASPALKNKRPRK 333
+ D P P S A K + +K
Sbjct: 1542 EKSDDDKKPKTDSPKSVASKADKRKK 1567
Score = 32.0 bits (71), Expect = 1.3
Identities = 41/184 (22%), Positives = 66/184 (35%), Gaps = 16/184 (8%)
Query: 246 SESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGA----QDS 301
S +++ T + K PGP A ++G KAA A ++S
Sbjct: 1073 SSVSSAPTLLKTKVADPGPASTGSNTTASD------SLGGSVPKAATTATPAATTSPKES 1126
Query: 302 EAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISR 361
A + PT+ PA + K R R S P GG +L + +I +
Sbjct: 1127 SEPPAPASSPEAASPTEQGPAGTSKKRGRKR---GMRSRPRANSGGVDLDSSGEFASIEK 1183
Query: 362 LVLEEDSQSTEP---SAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVE 418
++ D+ P +A N+ E A AP ++ K+ + K NS
Sbjct: 1184 MLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCL 1243
Query: 419 EKET 422
+K T
Sbjct: 1244 QKIT 1247
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 36.6 bits (83), Expect = 0.055
Identities = 45/192 (23%), Positives = 75/192 (39%), Gaps = 22/192 (11%)
Query: 218 QQKMLRFLESHLDDAEPYLLTMAKKALKSES------------AASSTGKEDKQPAPGPV 265
+QK +LE +D P LT + + E+ A SS KE+ +PA
Sbjct: 1112 KQKTQAYLEPESEDLIPSHLTSEVEKGEREASSSVAAIPAALPAQSSIVKEETKPASPHS 1171
Query: 266 EKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPA 325
P PA + PT +TLKAA D + A +K+ ++++V +Q A +
Sbjct: 1172 VLPDSVPAIKKEQEPT--AALTLKAA--------DEQMALSKVRKEEIVPDSQEATAHVS 1221
Query: 326 LKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAAS 385
K + N + ++ + K+ +LVL S+ + N +
Sbjct: 1222 QDQKMEPQPPNVPESEMKYSVLPDMVDEPKKGVKPKLVLNVTSELEQRKLSKNEPEVIKP 1281
Query: 386 APPSKPTVLNQP 397
P K T L+ P
Sbjct: 1282 YSPLKETSLSGP 1293
Score = 33.9 bits (76), Expect = 0.35
Identities = 60/298 (20%), Positives = 106/298 (35%), Gaps = 52/298 (17%)
Query: 167 KNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLE 226
+ KE K S++ K S D T + ++ + E+ LA P + S ET
Sbjct: 2759 EEKEQFKESELWKGG-SVDITKESMKEGFPSKESERTLARPFDETKSSET---------- 2807
Query: 227 SHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQL---RNPPTTI 283
PYLL+ K + A+ K+ P P R + ++ + +
Sbjct: 2808 ------PPYLLSPVKPQTLASGASPEINAVKKKEMPRSELTPERHTVHTIQTSKDDTSDV 2861
Query: 284 GMMTLKAAFKTLSGAQDSEA----AFAKLDQKDLVLPTQALPASPALKNKRPRKDENESS 339
++ + L A+D+ + AK + + T A A + NK K+ ++
Sbjct: 2862 PKQSVLVSKHHLEAAEDTRVKEPLSSAKSNYAQFISNTSASNADKMVSNKEMPKEPEDTY 2921
Query: 340 APADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPT-VLNQPL 398
A ED T AGL+ Q+ A + S+ +LN
Sbjct: 2922 AKG-----------------------EDFTVTSKPAGLSEDQKTAFSIISEGCEILNIHA 2958
Query: 399 PGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESE 456
P + S +++K ++EE F+ PD+ T K K +E+ +
Sbjct: 2959 PAF----ISSIDQEESEQMQDKLEYLEEKASFKTIPLPDDSETVACHKTLKSRLEDEK 3012
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,167,231
Number of Sequences: 37866
Number of extensions: 1006927
Number of successful extensions: 7103
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 288
Number of HSP's that attempted gapping in prelim test: 6430
Number of HSP's gapped (non-prelim): 961
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.