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Search of human proteins with 50312664
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50312664 ubiquitin specific protease 16 isoform b [Homo
sapiens]
(822 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 1671 0.0
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens] 1667 0.0
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens] 1667 0.0
gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens] 553 e-157
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 134 3e-31
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 100 7e-21
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 96 1e-19
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 91 6e-18
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 90 7e-18
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 90 7e-18
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 90 7e-18
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 89 2e-17
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 89 2e-17
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 88 4e-17
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 87 5e-17
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 87 8e-17
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 87 8e-17
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 86 1e-16
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 85 2e-16
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 84 7e-16
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 82 2e-15
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 82 2e-15
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ... 80 8e-15
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ... 80 8e-15
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 1671 bits (4328), Expect = 0.0
Identities = 822/822 (100%), Positives = 822/822 (100%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMA 180
NEVQYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMA
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMA 180
Query: 181 KENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDL 240
KENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDL
Sbjct: 181 KENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDL 240
Query: 241 ALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQ 300
ALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQ
Sbjct: 241 ALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQ 300
Query: 301 ELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGG 360
ELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGG
Sbjct: 301 ELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGG 360
Query: 361 ELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDN 420
ELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDN
Sbjct: 361 ELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDN 420
Query: 421 DSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEY 480
DSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEY
Sbjct: 421 DSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEY 480
Query: 481 EAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNIN 540
EAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNIN
Sbjct: 481 EAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNIN 540
Query: 541 MDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTP 600
MDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTP
Sbjct: 541 MDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTP 600
Query: 601 GTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQ 660
GTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQ
Sbjct: 601 GTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQ 660
Query: 661 CNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILD 720
CNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILD
Sbjct: 661 CNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILD 720
Query: 721 LAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDI 780
LAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDI
Sbjct: 721 LAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDI 780
Query: 781 PQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
PQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 781 PQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 1667 bits (4316), Expect = 0.0
Identities = 822/823 (99%), Positives = 822/823 (99%), Gaps = 1/823 (0%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKP-EKDNGNIELENKKLEKESKNEQEREKKENM 179
NEVQYCSSNQLGQVVDYVRKQASITTPKP EKDNGNIELENKKLEKESKNEQEREKKENM
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
Query: 180 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD
Sbjct: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
Query: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS
Sbjct: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
Query: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 359
QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG
Sbjct: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
Query: 360 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 419
GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD
Sbjct: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
Query: 420 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 479
NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE
Sbjct: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
Query: 480 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 539
YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI
Sbjct: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
Query: 540 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 599
NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT
Sbjct: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
Query: 600 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 659
PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR
Sbjct: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
Query: 660 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 719
QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL
Sbjct: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
Query: 720 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 779
DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD
Sbjct: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
Query: 780 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 1667 bits (4316), Expect = 0.0
Identities = 822/823 (99%), Positives = 822/823 (99%), Gaps = 1/823 (0%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKP-EKDNGNIELENKKLEKESKNEQEREKKENM 179
NEVQYCSSNQLGQVVDYVRKQASITTPKP EKDNGNIELENKKLEKESKNEQEREKKENM
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
Query: 180 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD
Sbjct: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
Query: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS
Sbjct: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
Query: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 359
QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG
Sbjct: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
Query: 360 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 419
GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD
Sbjct: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
Query: 420 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 479
NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE
Sbjct: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
Query: 480 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 539
YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI
Sbjct: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
Query: 540 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 599
NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT
Sbjct: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
Query: 600 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 659
PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR
Sbjct: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
Query: 660 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 719
QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL
Sbjct: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
Query: 720 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 779
DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD
Sbjct: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
Query: 780 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens]
Length = 814
Score = 553 bits (1424), Expect = e-157
Identities = 318/834 (38%), Positives = 479/834 (57%), Gaps = 49/834 (5%)
Query: 4 KRTKGKTVPID-DSSETLEP--VCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
KR+K TVP D DSS+ + C+H+ + ++K+A+ W++C +C + + D
Sbjct: 15 KRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDG 74
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
T + +WLCLKCG QGCG+NS+ QH+LKH+ + R+EPHC++++L W +WCY CD
Sbjct: 75 QLVLTSD---IWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD 131
Query: 121 NEVQ-YCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENM 179
++ +C+ L Q+VD+++K AS T + + K +E+ + + +
Sbjct: 132 EKLSTHCNKKVLAQIVDFLQKHASKT-------------QTSAFSRIMKLCEEKCETDEI 178
Query: 180 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
K N ++V+G++NLGNTCFFNAVMQNL+QT L +L+ E+K S T +KI P
Sbjct: 179 QKGGKCRN----LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSS 234
Query: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
+ +PL + L PGPLT A+ FL+ M+ET+KG ++PK LF+Q+C+KA RFK +QQQDS
Sbjct: 235 DSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDS 294
Query: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK-LDEELKNKVKDYEKKKSMPSFVDRIF 358
QELL YLLD +R EE +R+ ILKAF N T K D+E + KVK Y K+ +F+DRIF
Sbjct: 295 QELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIF 354
Query: 359 GGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSV-NDKNLKKTVEDEDQDSEEE 417
GELTS +MC++C +S V + F+D+SLP+++++ K + N +++ + D D
Sbjct: 355 IGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD---- 410
Query: 418 KDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPED 477
+ + + E P KH K K Q K R+ + N+ + + +
Sbjct: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEM-NGDS 469
Query: 478 SEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMK 537
+ + M+ + +N S++ H E + D + + ES +
Sbjct: 470 LMFASLMNSESRLNESPTDDSEKEASHSE---SNVDADSEPSESESASKQTGLFRSSSGS 526
Query: 538 NINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDE----INIEI 593
+ D L L++ Y E +G+ +++ L L++ + D+ N +
Sbjct: 527 GVQPDGPLYPLSAGKL-----LYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPL 581
Query: 594 LNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLC 653
++ + + + P+ AF TL+ + + ECSIQ CLYQFT E L NKLLC
Sbjct: 582 NISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLC 641
Query: 654 EVCTRRQCNGPKANIKGERK--HVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNK 711
E CT+ + + E+K VYTNA+KQ+LIS P VL LHLKRF QAG +LRKVN+
Sbjct: 642 ENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNR 701
Query: 712 HIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHL 771
H+ FP +LDLAPFC+ CKN A +VLY LYG+VEHSG+MR GHYTAY K RT + L
Sbjct: 702 HVDFPLMLDLAPFCSATCKN-ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKL 760
Query: 772 S-NLVLHGDIP--QDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
S + ++P + + ES GQW H+SDT++Q VP ++ L++QAYLLFYER+L
Sbjct: 761 SEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 134 bits (337), Expect = 3e-31
Identities = 178/829 (21%), Positives = 313/829 (37%), Gaps = 161/829 (19%)
Query: 8 GKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEE 67
GK I + C H+ E K+ L+ CQDCK
Sbjct: 23 GKQEKIPNKMSAFRNHCPHLDSVGEI--TKEDLIQKSLGTCQDCKVQG------------ 68
Query: 68 KPSVWLCL--KCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQY 125
P++W CL +C + GCG SQ H+ H + H L ++L VWCY C EV
Sbjct: 69 -PNLWACLENRCSYVGCGE-SQVDHSTIH---SQETKHYLTVNLTTLRVWCYACSKEVFL 123
Query: 126 CSSNQLGQVVDYVRKQASITTPKPE--KDNGNIELENKKLEKESKNEQEREKKENMAKEN 183
+ +VR+ I + K N L+ + + E ++++ +
Sbjct: 124 DRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARG 183
Query: 184 PPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALT 243
+ GL N+GNTC+ NA +Q LS P L + ++ LA T
Sbjct: 184 ----------LTGLKNIGNTCYMNAALQALSNCPPLTQFF-----------LDCGGLART 222
Query: 244 EPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELL 303
+ + P + +++ G V P LF + F+GY QQD+QE L
Sbjct: 223 D------KKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFL 276
Query: 304 RYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELT 363
R L+D L EELK +V + E+ + + + +
Sbjct: 277 RCLMD-----------------------LLHEELKEQVMEVEEDPQTITTEETMEEDKSQ 313
Query: 364 SMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDNDSY 423
S + C + S + ++++G + ++ N + T+ +D ++ E D
Sbjct: 314 SDVDFQSCESCSNSDRA---------ENENGSRCFSEDNNETTMLIQDDENNSEMSKDWQ 364
Query: 424 IKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEYEAE 483
++ + + + + + + + + Q+ ++ ++ H SEY +
Sbjct: 365 KEKMCNKINKVNSEGEFDKDRDSISETVDLNNQETVKVQI----------HSRASEYITD 414
Query: 484 MSLQGEVNIKSNHISQEGVMHKEYCVNQKDLN---GQA---KMIESVTDNQKSTEEVDMK 537
+ +++ S EGV + K N G A K +S + +K +
Sbjct: 415 VH-SNDLSTPQILPSNEGVNPRLSASPPKSGNLWPGLAPPHKKAQSASPKRKKQHKKYRS 473
Query: 538 NINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKN--LNLNAALHPDEI-NIEIL 594
I+ D +++S + +T + ++ + K L+++ HP I
Sbjct: 474 VISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGSC 533
Query: 595 NDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCE 654
+++ P + AF + F ++Q CL F ++L+ N CE
Sbjct: 534 GEAYAPQGWI----------AFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCE 583
Query: 655 VCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIK 714
C + + N K + P +L +HLKRF+ K++ H+
Sbjct: 584 KCKKLR-----------------NGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 626
Query: 715 FP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVVEHSGTMRSGHYTAYAKARTANSHL 771
FP E LDL PF +A+++ V Y L V+ H GT SGHY AY + ++L
Sbjct: 627 FPLEGLDLQPF-------LAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCR-----NNL 674
Query: 772 SNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 820
+NL W+ D V V + V N++AY+LFY +
Sbjct: 675 NNL-----------------WYEFDDQSVTEVSESTVQNAEAYVLFYRK 706
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 100 bits (248), Expect = 7e-21
Identities = 99/351 (28%), Positives = 144/351 (41%), Gaps = 47/351 (13%)
Query: 70 SVWLCLKCGHQGCGRNSQEQHALKHY------LTPRSEP-------HCLVLSLDNWSVWC 116
S W+CL C CGR HA KHY LT + H + + ++S +C
Sbjct: 37 SPWVCLTCSSVHCGRYVNG-HAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYC 95
Query: 117 YVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKK 176
Y CD+ V + +LG +V VR+ +N + K K +N K
Sbjct: 96 YRCDDFV--VNDTKLG-LVQKVREHLQ------NLENSAFTADRHKKRKLLENSTLNSK- 145
Query: 177 ENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIE 236
+ K N S I GL NLGNTCF NA++Q+LS KE+ V++
Sbjct: 146 --LLKVN---GSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPA----VELR 196
Query: 237 PPDLALTEPLEINLEPPGPLTLA--MSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGY 294
A + ++L + L + + + +P+ LF V K F+GY
Sbjct: 197 NGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGY 256
Query: 295 QQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKK---KSMP 351
QQQD+ E +RYLLD + E L+ N + +N K
Sbjct: 257 QQQDAHEFMRYLLDHLHLE---------LQGGFNGVSRSAILQENSTLSASNKCCINGAS 307
Query: 352 SFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKN 402
+ V IFGG L + + C C T S + FLDLSL + K+S N +N
Sbjct: 308 TVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQEN 358
Score = 80.9 bits (198), Expect = 4e-15
Identities = 62/213 (29%), Positives = 93/213 (43%), Gaps = 52/213 (24%)
Query: 611 DPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKG 670
D + F + ++ N CS++ CL FT E+L + +C C ++Q
Sbjct: 343 DIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQ---------- 392
Query: 671 ERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKC 729
+ K+ I P VL LHLKRF + KV+ +++FP LD +KC
Sbjct: 393 -------KSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLD------MKC 439
Query: 730 KNVAEENT---RVLYSLYGVVEHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFE 785
+ EN+ LY L VV H G+ + SGHYTAYA
Sbjct: 440 YLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYA----------------------- 476
Query: 786 MESKGQWFHISDTHVQAVPTTKVLNSQAYLLFY 818
+G+WFH +D+ V V+ ++AY+LFY
Sbjct: 477 -THEGRWFHFNDSTVTLTDEETVVKAKAYILFY 508
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 95.9 bits (237), Expect = 1e-19
Identities = 64/193 (33%), Positives = 99/193 (51%), Gaps = 14/193 (7%)
Query: 196 GLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGP 255
GLSNLGNTCF N+ +Q LS TP L E K +L PL + G
Sbjct: 261 GLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQ--------EELNFDNPLGMR----GE 308
Query: 256 LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEH 315
+ + ++ + +M K VTP+ +QV + A +F GYQQQD QELL +LLDG+ E+
Sbjct: 309 IAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLH-EDL 367
Query: 316 QRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVS 375
R+ K ++ + D+ + + + K++ VD IF G S ++C +C +S
Sbjct: 368 NRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVD-IFHGLFKSTLVCPECAKIS 426
Query: 376 LVHESFLDLSLPV 388
+ + F L+LP+
Sbjct: 427 VTFDPFCYLTLPL 439
Score = 67.4 bits (163), Expect = 5e-11
Identities = 49/190 (25%), Positives = 78/190 (41%), Gaps = 46/190 (24%)
Query: 632 IQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPV 691
++ C+ FT EKL + C C Q A K++ + PPV
Sbjct: 759 LKDCIELFTTKEKLGAEDPWYCPNCKEHQ-----------------QATKKLDLWSLPPV 801
Query: 692 LTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHS 750
L +HLKRF + + K++ + FP LD++ F + Y+L V H
Sbjct: 802 LVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFL------INPNAGPCRYNLIAVSNHY 855
Query: 751 GTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLN 810
G M GHYTA+AK + G+W++ D+ V ++++
Sbjct: 856 GGMGGGHYTAFAKNK----------------------DDGKWYYFDDSSVSTASEDQIVS 893
Query: 811 SQAYLLFYER 820
AY+LFY+R
Sbjct: 894 KAAYVLFYQR 903
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 90.5 bits (223), Expect = 6e-18
Identities = 104/431 (24%), Positives = 167/431 (38%), Gaps = 67/431 (15%)
Query: 8 GKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEE 67
GK I + C H+ E K+ L+ CQDCK
Sbjct: 23 GKQEKIPNKMSAFRNHCPHLDSVGEI--TKEDLIQKSLGTCQDCKVQG------------ 68
Query: 68 KPSVWLCL--KCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQY 125
P++W CL +C + GCG SQ H+ H + H L ++L VWCY C EV
Sbjct: 69 -PNLWACLENRCSYVGCGE-SQVDHSTIH---SQETKHYLTVNLTTLRVWCYACSKEVFL 123
Query: 126 CSSNQLGQVVDYVRKQASITTPKPE--KDNGNIELENKKLEKESKNEQEREKKENMAKEN 183
+ +VR+ I + K N L+ + + E ++++ +
Sbjct: 124 DRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARG 183
Query: 184 PPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALT 243
+ GL N+GNTC+ NA +Q LS P L + ++ LA T
Sbjct: 184 ----------LTGLKNIGNTCYMNAALQALSNCPPLTQFF-----------LDCGGLART 222
Query: 244 EPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELL 303
+ + P + +++ G V P LF + F+GY QQD+QE L
Sbjct: 223 D------KKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFL 276
Query: 304 RYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVK-DYEKKKSMPSFVDRIFGGEL 362
R L+D + E ++V + +TE+ EE K++ D++ +S S DR
Sbjct: 277 RCLMDLLHEELKEQVMEVEEDPQTITTEETMEEDKSQSDVDFQSCESC-SNSDRAENENG 335
Query: 363 TSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKK---TVEDEDQDSEEEKD 419
+ D T L+ DD++ + D +K + + + E +KD
Sbjct: 336 SRCFSEDNNETTMLIQ-----------DDENNSEMSKDWQKEKMCNKINKVNSEGEFDKD 384
Query: 420 NDSYIKERSDI 430
DS I E D+
Sbjct: 385 RDS-ISETVDL 394
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 49/193 (25%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
++Q CL F ++L+ N CE C + + N K + P
Sbjct: 568 TLQDCLAAFFARDELKGDNMYSCEKCKKLR-----------------NGVKFCKVQNFPE 610
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVV 747
+L +HLKRF+ K++ H+ FP E LDL PF +A+++ V Y L V+
Sbjct: 611 ILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPF-------LAKDSPAQIVTYDLLSVI 663
Query: 748 EHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTK 807
H GT SGHY AY + ++L+NL W+ D V V +
Sbjct: 664 CHHGTASSGHYIAYCR-----NNLNNL-----------------WYEFDDQSVTEVSEST 701
Query: 808 VLNSQAYLLFYER 820
V N++AY+LFY +
Sbjct: 702 VQNAEAYVLFYRK 714
Score = 36.6 bits (83), Expect = 0.097
Identities = 18/47 (38%), Positives = 26/47 (55%)
Query: 342 KDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
K ++ K S + IF G + S + C C VS+ E+F DLSLP+
Sbjct: 463 KRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPI 509
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 90.1 bits (222), Expect = 7e-18
Identities = 98/402 (24%), Positives = 159/402 (39%), Gaps = 65/402 (16%)
Query: 37 KKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCL--KCGHQGCGRNSQEQHALKH 94
K+ L+ CQDCK P++W CL +C + GCG SQ H+ H
Sbjct: 19 KEDLIQKSLGTCQDCKVQG-------------PNLWACLENRCSYVGCGE-SQVDHSTIH 64
Query: 95 YLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPE--KD 152
+ H L ++L VWCY C EV + +VR+ I + K
Sbjct: 65 ---SQETKHYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQENSVQDFKI 121
Query: 153 NGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQN 212
N L+ + + E ++++ + + GL N+GNTC+ NA +Q
Sbjct: 122 PSNTTLKTPLVAVFDDLDIEADEEDELRARG----------LTGLKNIGNTCYMNAALQA 171
Query: 213 LSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKK 272
LS P L + ++ LA T+ + P + +++
Sbjct: 172 LSNCPPLTQFF-----------LDCGGLARTD------KKPAICKSYLKLMTELWHKSRP 214
Query: 273 GVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK 332
G V P LF + F+GY QQD+QE LR L+D + E ++V + +TE+
Sbjct: 215 GSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVMEVEEDPQTITTEE 274
Query: 333 LDEELKNKVK-DYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDD 391
EE K++ D++ +S S DR + D T L+ DD
Sbjct: 275 TMEEDKSQSDVDFQSCESC-SNSDRAENENGSRCFSEDNNETTMLIQ-----------DD 322
Query: 392 QSGKKSVNDKNLKK---TVEDEDQDSEEEKDNDSYIKERSDI 430
++ + D +K + + + E +KD DS I E D+
Sbjct: 323 ENNSEMSKDWQKEKMCNKINKVNSEGEFDKDRDS-ISETVDL 363
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 49/193 (25%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
++Q CL F ++L+ N CE C + + N K + P
Sbjct: 537 TLQDCLAAFFARDELKGDNMYSCEKCKKLR-----------------NGVKFCKVQNFPE 579
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVV 747
+L +HLKRF+ K++ H+ FP E LDL PF +A+++ V Y L V+
Sbjct: 580 ILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPF-------LAKDSPAQIVTYDLLSVI 632
Query: 748 EHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTK 807
H GT SGHY AY + ++L+NL W+ D V V +
Sbjct: 633 CHHGTASSGHYIAYCR-----NNLNNL-----------------WYEFDDQSVTEVSEST 670
Query: 808 VLNSQAYLLFYER 820
V N++AY+LFY +
Sbjct: 671 VQNAEAYVLFYRK 683
Score = 36.6 bits (83), Expect = 0.097
Identities = 18/47 (38%), Positives = 26/47 (55%)
Query: 342 KDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
K ++ K S + IF G + S + C C VS+ E+F DLSLP+
Sbjct: 432 KRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPI 478
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 90.1 bits (222), Expect = 7e-18
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 14/204 (6%)
Query: 185 PMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTE 244
P +S Q + GL NLGNTCF N+ +Q LS T L + + + I + P
Sbjct: 292 PPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNP------- 344
Query: 245 PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLR 304
L G + A ++ + +M + V P+ +QV + A +F GYQQQDSQELL
Sbjct: 345 -----LGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLA 399
Query: 305 YLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTS 364
+LLDG+ E+ RV K ++ + D + + + + ++ VD F G S
Sbjct: 400 FLLDGLH-EDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVD-TFHGLFKS 457
Query: 365 MIMCDQCRTVSLVHESFLDLSLPV 388
++C +C VS+ + F L+LP+
Sbjct: 458 TLVCPECAKVSVTFDPFCYLTLPL 481
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 48/192 (25%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
+++ C+ FT E L + + C C + Q A K+ + P
Sbjct: 777 ALRDCIELFTTMETLGEHDPWYCPNCKKHQ-----------------QATKKFDLWSLPK 819
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPF-CTLKCKNVAEENTRVLYSLYGVVE 748
+L +HLKRF + K++ ++FP L+++ F C L + +Y L V
Sbjct: 820 ILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPY-------VYDLIAVSN 872
Query: 749 HSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 808
H G M GHYTAYAK + G+W++ D++V ++
Sbjct: 873 HYGAMGVGHYTAYAKNKL----------------------NGKWYYFDDSNVSLASEDQI 910
Query: 809 LNSQAYLLFYER 820
+ AY+LFY+R
Sbjct: 911 VTKAAYVLFYQR 922
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 90.1 bits (222), Expect = 7e-18
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 14/204 (6%)
Query: 185 PMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTE 244
P +S Q + GL NLGNTCF N+ +Q LS T L + + + I + P
Sbjct: 245 PPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNP------- 297
Query: 245 PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLR 304
L G + A ++ + +M + V P+ +QV + A +F GYQQQDSQELL
Sbjct: 298 -----LGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLA 352
Query: 305 YLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTS 364
+LLDG+ E+ RV K ++ + D + + + + ++ VD F G S
Sbjct: 353 FLLDGLH-EDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVD-TFHGLFKS 410
Query: 365 MIMCDQCRTVSLVHESFLDLSLPV 388
++C +C VS+ + F L+LP+
Sbjct: 411 TLVCPECAKVSVTFDPFCYLTLPL 434
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 48/192 (25%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
+++ C+ FT E L + + C C + Q A K+ + P
Sbjct: 730 ALRDCIELFTTMETLGEHDPWYCPNCKKHQ-----------------QATKKFDLWSLPK 772
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPF-CTLKCKNVAEENTRVLYSLYGVVE 748
+L +HLKRF + K++ ++FP L+++ F C L + +Y L V
Sbjct: 773 ILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPY-------VYDLIAVSN 825
Query: 749 HSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 808
H G M GHYTAYAK + G+W++ D++V ++
Sbjct: 826 HYGAMGVGHYTAYAKNKL----------------------NGKWYYFDDSNVSLASEDQI 863
Query: 809 LNSQAYLLFYER 820
+ AY+LFY+R
Sbjct: 864 VTKAAYVLFYQR 875
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 88.6 bits (218), Expect = 2e-17
Identities = 70/254 (27%), Positives = 112/254 (44%), Gaps = 32/254 (12%)
Query: 146 TPKPEKDNGNIE-------LENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLS 198
TPKPE + + + + + +S E+E E+K+ C GL
Sbjct: 452 TPKPETHLASPKPTCMVPPMPHSPVSGDSVEEEEEEEKK-----------VCLPGFTGLV 500
Query: 199 NLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTL 258
NLGNTCF N+V+Q+LS T LR+ + I P L G L +
Sbjct: 501 NLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNP------------LGTGGRLAI 548
Query: 259 AMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRV 318
+ L + + P +L + V KA +F GY Q D+QE + +LLDG+ E+ R+
Sbjct: 549 GFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLH-EDLNRI 607
Query: 319 SKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVH 378
+S + DE + + K ++ SF+ +F G+ S ++C C VS+
Sbjct: 608 QNKPYTETVDSDGRPDEVVAEEAWQRHKMRN-DSFIVDLFQGQYKSKLVCPVCAKVSITF 666
Query: 379 ESFLDLSLPVLDDQ 392
+ FL L +P+ Q
Sbjct: 667 DPFLYLPVPLPQKQ 680
Score = 70.9 bits (172), Expect = 5e-12
Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 47/214 (21%)
Query: 610 EDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIK 669
EDP +A E ++ CL FTR E L C C + +
Sbjct: 1044 EDPGSA------GEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHR--------- 1088
Query: 670 GERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLR-KVNKHIKFP-EILDLAPFCTL 727
A KQ+L+ P VL + LKRF F R K+N ++FP LDL+ FC
Sbjct: 1089 --------EASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIG 1140
Query: 728 KCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQD-FEM 786
+ +E Y LY V+ H G M GHYTA A+ +P D
Sbjct: 1141 Q-----KEEQLPSYDLYAVINHYGGMIGGHYTACAR----------------LPNDRSSQ 1179
Query: 787 ESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 820
S W D+ V V ++V+ AY+LFY R
Sbjct: 1180 RSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRR 1213
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 19/205 (9%)
Query: 186 MNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP 245
MNS + GL NLGNTCF N+++Q LS T LR+ + + AL E
Sbjct: 258 MNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEE 317
Query: 246 LEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRY 305
++ T+ S + VV+P E +Q+ + A RF GY QQD+QE LR+
Sbjct: 318 FAKLIQ-----TIWTS--------SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRF 364
Query: 306 LLDGMRAEEHQRVSKGILKAFGN--STEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELT 363
LLDG+ H V++ L+ N + + L ++ K + + + S + +F G+L
Sbjct: 365 LLDGL----HNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLK 420
Query: 364 SMIMCDQCRTVSLVHESFLDLSLPV 388
S + C C S V + F DLSLP+
Sbjct: 421 SSLTCTDCGYCSTVFDPFWDLSLPI 445
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/193 (31%), Positives = 83/193 (43%), Gaps = 49/193 (25%)
Query: 629 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 688
E ++ C+ FT+ + L K C C +C G K IK + I
Sbjct: 452 EVTLMDCMRLFTKEDVLDGDEKPTC--C---RCRGRKRCIK------------KFSIQRF 494
Query: 689 PPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR-VLYSLYGV 746
P +L LHLKRF ++ K+ + FP LDL F A ENT +Y+LY V
Sbjct: 495 PKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF--------ASENTNHAVYNLYAV 546
Query: 747 VEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 806
HSGT GHYTAY ++ G+W +D+ V + ++
Sbjct: 547 SNHSGTTMGGHYTAYCRS----------------------PGTGEWHTFNDSSVTPMSSS 584
Query: 807 KVLNSQAYLLFYE 819
+V S AYLLFYE
Sbjct: 585 QVRTSDAYLLFYE 597
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 87.8 bits (216), Expect = 4e-17
Identities = 66/208 (31%), Positives = 100/208 (48%), Gaps = 19/208 (9%)
Query: 183 NPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLAL 242
N NS + GL NLGNTCF N+++Q LS T LR+ + + AL
Sbjct: 46 NKAKNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTAL 105
Query: 243 TEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQEL 302
E ++ T+ S + VV+P E +Q+ + A RF GY QQD+QE
Sbjct: 106 VEEFAKLIQ-----TIWTS--------SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEF 152
Query: 303 LRYLLDGMRAEEHQRVSKGILKAFGN--STEKLDEELKNKVKDYEKKKSMPSFVDRIFGG 360
LR+LLDG+ H V++ L+ N + + L ++ K + + + S + +F G
Sbjct: 153 LRFLLDGL----HNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVG 208
Query: 361 ELTSMIMCDQCRTVSLVHESFLDLSLPV 388
+L S + C C S V + F DLSLP+
Sbjct: 209 QLKSSLTCTDCGYCSTVFDPFWDLSLPI 236
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/193 (31%), Positives = 83/193 (43%), Gaps = 49/193 (25%)
Query: 629 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 688
E ++ C+ FT+ + L K C C +C G K IK + I
Sbjct: 243 EVTLMDCMRLFTKEDVLDGDEKPTC--C---RCRGRKRCIK------------KFSIQRF 285
Query: 689 PPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR-VLYSLYGV 746
P +L LHLKRF ++ K+ + FP LDL F A ENT +Y+LY V
Sbjct: 286 PKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF--------ASENTNHAVYNLYAV 337
Query: 747 VEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 806
HSGT GHYTAY ++ G+W +D+ V + ++
Sbjct: 338 SNHSGTTMGGHYTAYCRS----------------------PGTGEWHTFNDSSVTPMSSS 375
Query: 807 KVLNSQAYLLFYE 819
+V S AYLLFYE
Sbjct: 376 QVRTSDAYLLFYE 388
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 87.4 bits (215), Expect = 5e-17
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 49/220 (22%)
Query: 609 NEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANI 668
+++PE A T++ R+ S+ CL FTR E L + K+ C C
Sbjct: 527 SQNPERADSTVS-RDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQS---------- 575
Query: 669 KGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLK 728
Y + KQ+ + P V HLKRF+ G RK+N I FP LD+ PF
Sbjct: 576 -------YQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLAST 628
Query: 729 CKNVAEEN--------TRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDI 780
++ +E YSL+ V+ H GT+ SGHYT++ +
Sbjct: 629 KESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIR----------------- 671
Query: 781 PQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 820
+ K QWF D + +L S+ YLLFY +
Sbjct: 672 ------QQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHK 705
Score = 80.5 bits (197), Expect = 6e-15
Identities = 84/340 (24%), Positives = 132/340 (38%), Gaps = 49/340 (14%)
Query: 74 CLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQ 133
CL C GC E+H KH T + H L + L + ++C++C + V Q+ +
Sbjct: 249 CLSCVFFGC---FTEKHIHKHAETKQ---HHLAVDLYHGVIYCFMCKDYVYDKDIEQIAK 302
Query: 134 VVD--YVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQ 191
+R S +T + E+K+ E+K E+E K K+ S
Sbjct: 303 ETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETK---EQEPKLVKPKKKRRKKSVYT 359
Query: 192 ITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLE 251
+ ++GL NLGNTCF N ++Q L+ P+L++ K I
Sbjct: 360 VGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKC-----------------IMTS 402
Query: 252 PPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMR 311
P L MS + M + P +L + A GY+QQD+ E L +LD +
Sbjct: 403 PSLCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVL- 461
Query: 312 AEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQC 371
H + G +E N +D+IF G L S + C C
Sbjct: 462 -HRHSKDDSG------------GQEANN-------PNCCNCIIDQIFTGGLQSDVTCQAC 501
Query: 372 RTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDED 411
+VS + D+SL + + S N + TV +D
Sbjct: 502 HSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDD 541
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 86.7 bits (213), Expect = 8e-17
Identities = 58/211 (27%), Positives = 86/211 (40%), Gaps = 49/211 (23%)
Query: 619 LANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTN 678
+ N E + ++ CL +FTR E L + K+ C C H Y
Sbjct: 349 VVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGC-----------------HSYQE 391
Query: 679 AKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKN------- 731
+ KQ+ + P V HLKRF+ + RK+ ++ FP LD+ PF ++
Sbjct: 392 STKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQ 451
Query: 732 --VAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESK 789
N YSL+ VV H GT+ SGHYT++ + + K
Sbjct: 452 QPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIR-----------------------QHK 488
Query: 790 GQWFHISDTHVQAVPTTKVLNSQAYLLFYER 820
QWF D + VL+S+ YLLFY +
Sbjct: 489 DQWFKCDDAIITKASIKDVLDSEGYLLFYHK 519
Score = 80.9 bits (198), Expect = 4e-15
Identities = 82/322 (25%), Positives = 126/322 (39%), Gaps = 77/322 (23%)
Query: 74 CLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQ 133
CL C GC ++H +H +++ H L + L ++C++C
Sbjct: 76 CLYCVFFGC---FTKKHIHEH---AKAKRHNLAIDLMYGGIYCFLCQ------------- 116
Query: 134 VVDYVR-KQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPP---MNSP 189
DY+ K I + ++ ++ +K ++E E + K NP + S
Sbjct: 117 --DYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELE----LLKHNPKRRKITSN 170
Query: 190 CQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEIN 249
C I ++GL NLGNTCF N ++Q L+ TP+LR D L++
Sbjct: 171 CTIGLRGLINLGNTCFMNCIVQALTHTPLLR------------------DFFLSDRHRCE 212
Query: 250 LEPPGP-LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLD 308
++ P L MS E + P +L V A GY+QQD+ E L LD
Sbjct: 213 MQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALD 272
Query: 309 GMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPS----FVDRIFGGELTS 364
+ R KG D KK + P+ +D+IF G L S
Sbjct: 273 VL-----HRHCKG--------------------DDNGKKANNPNHCNCIIDQIFTGGLQS 307
Query: 365 MIMCDQCRTVSLVHESFLDLSL 386
+ C C VS + F D+SL
Sbjct: 308 DVTCQVCHGVSTTIDPFWDISL 329
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 86.7 bits (213), Expect = 8e-17
Identities = 84/310 (27%), Positives = 140/310 (45%), Gaps = 34/310 (10%)
Query: 79 HQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYV 138
+ GC Q + YL+ R L + ++ +W Y +N + ++Y+
Sbjct: 638 YTGCFSRMQTIKEIHEYLSQR-----LRIKEEDMRLWLYNSENYLTLLDDED--HKLEYL 690
Query: 139 RKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLS 198
+ Q ++ + IE+ NK + +E N +K + P + GLS
Sbjct: 691 KIQ--------DEQHLVIEVRNKDMSWP----EEMSFIANSSKIDRH-KVPTEKGATGLS 737
Query: 199 NLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTL 258
NLGNTCF N+ +Q +S T L + +SG + +L T P+ + G +
Sbjct: 738 NLGNTCFMNSSIQCVSNTQPLTQYF----ISGRHLY----ELNRTNPIGMK----GHMAK 785
Query: 259 AMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRV 318
+ E+ + V P +L + K A RF G+QQQDSQELL +LLDG+ E+ RV
Sbjct: 786 CYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLDGLH-EDLNRV 844
Query: 319 SKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVH 378
+ +S + D E+ + D +++ VD +F G+L S + C C +S+
Sbjct: 845 HEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVD-LFHGQLRSQVKCKTCGHISVRF 903
Query: 379 ESFLDLSLPV 388
+ F LSLP+
Sbjct: 904 DPFNFLSLPL 913
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 25/88 (28%)
Query: 735 ENTRV--LYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQW 792
E+TR+ +Y+LY + HSG + GHY YAK +W
Sbjct: 1502 EDTRIKPIYNLYAISCHSGILGGGHYVTYAK-----------------------NPNCKW 1538
Query: 793 FHISDTHVQAVPTTKVLNSQAYLLFYER 820
+ +D+ + + ++ AY+LFYE+
Sbjct: 1539 YCYNDSSCKELHPDEIDTDSAYILFYEQ 1566
Score = 38.9 bits (89), Expect = 0.020
Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 22/115 (19%)
Query: 602 TKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQC 661
T VV+E A E N D C L FT E+L + C C
Sbjct: 1210 TSQERVVDEHESVEQSRRAQAEPINLDSC-----LRAFTSEEELGENEMYYCSKCK---- 1260
Query: 662 NGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP 716
+ A K++ + PP+L +HLKRFQ K K +KFP
Sbjct: 1261 -------------THCLATKKLDLWRLPPILIIHLKRFQFVNGRWIKSQKIVKFP 1302
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 86.3 bits (212), Expect = 1e-16
Identities = 64/200 (32%), Positives = 100/200 (50%), Gaps = 14/200 (7%)
Query: 189 PCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEI 248
P + GLSNLGNTCF N+ +Q +S T L + +SG + +L T P+ +
Sbjct: 526 PTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYF----ISGRHLY----ELNRTNPIGM 577
Query: 249 NLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLD 308
G + + E+ + V P +L + K A +F G+QQQDSQELL +LLD
Sbjct: 578 K----GHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLD 633
Query: 309 GMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMC 368
G+ E+ RV + +S + D E+ + D +++ VD +F G+L S + C
Sbjct: 634 GLH-EDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVD-LFHGQLRSQVKC 691
Query: 369 DQCRTVSLVHESFLDLSLPV 388
C +S+ + F LSLP+
Sbjct: 692 KTCGHISVRFDPFNFLSLPL 711
Score = 37.7 bits (86), Expect = 0.044
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 25/88 (28%)
Query: 735 ENTRV--LYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQW 792
E+T + +Y+LY + HSG + GHY YAK +W
Sbjct: 1304 EDTHIKPIYNLYAISCHSGILSGGHYITYAK-----------------------NPNCKW 1340
Query: 793 FHISDTHVQAVPTTKVLNSQAYLLFYER 820
+ +D+ + + ++ AY+LFYE+
Sbjct: 1341 YCYNDSSCEELHPDEIDTDSAYILFYEQ 1368
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
++ CL FT E+L ++ C C + A K++ + PP
Sbjct: 1032 NLDSCLRAFTSEEELGESEMYYCSKCK-----------------THCLATKKLDLWRLPP 1074
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKF 715
L +HLKRFQ K K ++F
Sbjct: 1075 FLIIHLKRFQFVNDQWIKSQKIVRF 1099
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 626 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 685
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 686 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 744
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 745 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 804
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 805 TTKVLNSQAYLLFY 818
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 71.6 bits (174), Expect = 3e-12
Identities = 66/263 (25%), Positives = 108/263 (41%), Gaps = 25/263 (9%)
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
SS + Q + K+ TP ++N K K E R + NP
Sbjct: 718 SSPDITQAIQEEEKRKPTVTPTVNREN--------KPTCYPKAEISRLSASQIRNLNPVF 769
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
+ GL NLGNTC+ N+++Q L P L + I +
Sbjct: 770 GGSGP-ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------- 819
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYL 306
L G + + + + ++PK+ + K +F GY QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 307 LDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSM 365
+DG+ + ++ ++ K N + LD + K ++K K + S + +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKST 933
Query: 366 IMCDQCRTVSLVHESFLDLSLPV 388
+ C C S E+F+ LSLP+
Sbjct: 934 VQCLTCHKKSRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 395 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 454
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 455 RQQKIQGKVLHLNDICTIDHPEDSEYE 481
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 626 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 685
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 686 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 744
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 745 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 804
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 805 TTKVLNSQAYLLFY 818
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 71.6 bits (174), Expect = 3e-12
Identities = 66/263 (25%), Positives = 108/263 (41%), Gaps = 25/263 (9%)
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
SS + Q + K+ TP ++N K K E R + NP
Sbjct: 718 SSPDITQAIQEEEKRKPTVTPTVNREN--------KPTCYPKAEISRLSASQIRNLNPVF 769
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
+ GL NLGNTC+ N+++Q L P L + I +
Sbjct: 770 GGSGP-ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------- 819
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYL 306
L G + + + + ++PK+ + K +F GY QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 307 LDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSM 365
+DG+ + ++ ++ K N + LD + K ++K K + S + +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKST 933
Query: 366 IMCDQCRTVSLVHESFLDLSLPV 388
+ C C S E+F+ LSLP+
Sbjct: 934 VQCLTCHKKSRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 395 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 454
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 455 RQQKIQGKVLHLNDICTIDHPEDSEYE 481
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 626 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 685
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 686 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 744
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 745 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 804
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 805 TTKVLNSQAYLLFY 818
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 71.6 bits (174), Expect = 3e-12
Identities = 66/263 (25%), Positives = 108/263 (41%), Gaps = 25/263 (9%)
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
SS + Q + K+ TP ++N K K E R + NP
Sbjct: 718 SSPDITQAIQEEEKRKPTVTPTVNREN--------KPTCYPKAEISRLSASQIRNLNPVF 769
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
+ GL NLGNTC+ N+++Q L P L + I +
Sbjct: 770 GGSGP-ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------- 819
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYL 306
L G + + + + ++PK+ + K +F GY QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 307 LDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSM 365
+DG+ + ++ ++ K N + LD + K ++K K + S + +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKST 933
Query: 366 IMCDQCRTVSLVHESFLDLSLPV 388
+ C C S E+F+ LSLP+
Sbjct: 934 VQCLTCHKKSRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 395 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 454
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 455 RQQKIQGKVLHLNDICTIDHPEDSEYE 481
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 85.1 bits (209), Expect = 2e-16
Identities = 67/233 (28%), Positives = 107/233 (45%), Gaps = 16/233 (6%)
Query: 156 IELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQ 215
I +E +K + + Q NM++E+ Q + GL+NLGNTCF N+ +Q LS
Sbjct: 272 IIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKG--QPGICGLTNLGNTCFMNSALQCLSN 329
Query: 216 TPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVV 275
P L E + +L PL + G + A + + + +
Sbjct: 330 VPQLTEYF--------LNNCYLEELNFRNPLGMK----GEIAEAYADLVKQAWSGHHRSI 377
Query: 276 TPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDE 335
P ++V A +F GYQQ DSQELL +LLDG+ E+ RV K ++ + D+
Sbjct: 378 VPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLH-EDLNRVKKKEYVELCDAAGRPDQ 436
Query: 336 ELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
E+ + K+++ VD F G S ++C C VS+ + F LS+P+
Sbjct: 437 EVAQEAWQNHKRRNDSVIVD-TFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPL 488
Score = 70.1 bits (170), Expect = 8e-12
Identities = 53/190 (27%), Positives = 77/190 (40%), Gaps = 42/190 (22%)
Query: 632 IQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPV 691
+Q C+ FT E L N C C + Q A K++ + + P +
Sbjct: 781 LQECIELFTTVETLEKENPWYCPSCKQHQL-----------------ATKKLDLWMLPEI 823
Query: 692 LTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEHS 750
L +HLKRF F+ K++ ++FP I DL F + E N + Y L V H
Sbjct: 824 LIIHLKRFSYTKFSREKLDTLVEFP-IRDL-DFSEFVIQPQNESNPELYKYDLIAVSNHY 881
Query: 751 GTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLN 810
G MR GHYT +A + GQW + D V V ++ +
Sbjct: 882 GGMRDGHYTTFACNK----------------------DSGQWHYFDDNSVSPVNENQIES 919
Query: 811 SQAYLLFYER 820
AY+LFY+R
Sbjct: 920 KAAYVLFYQR 929
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 83.6 bits (205), Expect = 7e-16
Identities = 55/199 (27%), Positives = 80/199 (40%), Gaps = 49/199 (24%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
++ CL +FTR E L + K+ C C Y + KQ+ ++ P
Sbjct: 262 TLTDCLRRFTRPEHLGSSAKIKCGSCQS-----------------YQESTKQLTMNKLPV 304
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKN---------VAEENTRVLY 741
V H KRF+ + RK+ +I FP LD+ PF ++ N Y
Sbjct: 305 VACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKY 364
Query: 742 SLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQ 801
SL+ VV H GT+ SGHYT++ + K QWF D +
Sbjct: 365 SLFAVVNHQGTLESGHYTSFIR-----------------------HHKDQWFKCDDAVIT 401
Query: 802 AVPTTKVLNSQAYLLFYER 820
VL+S+ YLLFY +
Sbjct: 402 KASIKDVLDSEGYLLFYHK 420
Score = 62.8 bits (151), Expect = 1e-09
Identities = 68/274 (24%), Positives = 105/274 (38%), Gaps = 51/274 (18%)
Query: 117 YVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKK 176
YV D +++ + + G+ + + QAS +T + L K E+ +
Sbjct: 5 YVYDKDIEQIAKEEQGEAL---KLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELLG 61
Query: 177 ENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIE 236
N + + S I ++GL NLGNTCF N ++Q L+ TP+LR+ + ++
Sbjct: 62 HNPRRRR--ITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHR---CEMP 116
Query: 237 PPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQ 296
P+L L MS E+ P +L V A GY+Q
Sbjct: 117 SPELC--------------LVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQ 162
Query: 297 QDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPS---- 352
QD+ E L LD + R KG D K + P+
Sbjct: 163 QDAHEFLIAALDVL-----HRHCKG--------------------DDVGKAANNPNHCNC 197
Query: 353 FVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSL 386
+D+IF G L S + C C VS + D+SL
Sbjct: 198 IIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISL 231
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 82.4 bits (202), Expect = 2e-15
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 630 CSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAP 689
C + L +FT E L + +C+ QCN + + V T A+KQ++I P
Sbjct: 515 CLVTEMLAKFTETEAL-EGKIYVCD-----QCNSKRRRFSS-KPVVLTEAQKQLMICHLP 567
Query: 690 PVLTLHLKRFQQAGFNLR-KVNKHIKFPEILDLAPFCTLK-CKNVAEENTRVLYSLYGVV 747
VL LHLKRF+ +G N R K+ H+ F EIL++ P+C + K++ E +Y L VV
Sbjct: 568 QVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPE--CFIYDLSAVV 625
Query: 748 EHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 806
H G SGHYTAY + E G W H +D+ +
Sbjct: 626 MHHGKGFGSGHYTAYC---------------------YNSEG-GFWVHCNDSKLSMCTMD 663
Query: 807 KVLNSQAYLLFY 818
+V +QAY+LFY
Sbjct: 664 EVCKAQAYILFY 675
Score = 63.9 bits (154), Expect = 6e-10
Identities = 73/301 (24%), Positives = 117/301 (38%), Gaps = 75/301 (24%)
Query: 134 VVDYVRKQASITTP-KPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQI 192
+++ V Q TP P KD K+ S+NE ++ ++ K P +
Sbjct: 224 IIEIVSVQVPAQTPASPAKD---------KVLSTSENEISQKVSDSSVKRRPIVTPG--- 271
Query: 193 TVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIV--------KIEPPDLALTE 244
V GL NLGNTC+ N+V+Q LS + R+ ++ ++ + + P + T
Sbjct: 272 -VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 245 PLEIN---------------------------------LEPPGPLTLAMS------QFLN 265
++N ++P P + +S
Sbjct: 331 VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQ 390
Query: 266 EMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKA 325
M K +V+P + V + F+GY QQD+QE L LLD ++ E L+
Sbjct: 391 VMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LET 441
Query: 326 FGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLS 385
G S L + K+ K + + V+ IF G+L S + C C S E F DLS
Sbjct: 442 TGTSLPALIPTSQRKL-----IKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
Query: 386 L 386
L
Sbjct: 497 L 497
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 20/100 (20%)
Query: 24 CRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCG 83
C+H+ + L+ +L +W+ C DC T S+W CL C H CG
Sbjct: 7 CKHVGQ-LQLAQDHSSLNPQKWH-CVDCNTTE--------------SIWACLSCSHVACG 50
Query: 84 RNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV 123
R E+HALKH+ + H + L ++ V+CY+CD+ V
Sbjct: 51 RYI-EEHALKHF---QESSHPVALEVNEMYVFCYLCDDYV 86
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 82.4 bits (202), Expect = 2e-15
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 630 CSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAP 689
C + L +FT E L + +C+ QCN + + V T A+KQ++I P
Sbjct: 515 CLVTEMLAKFTETEAL-EGKIYVCD-----QCNSKRRRFSS-KPVVLTEAQKQLMICHLP 567
Query: 690 PVLTLHLKRFQQAGFNLR-KVNKHIKFPEILDLAPFCTLK-CKNVAEENTRVLYSLYGVV 747
VL LHLKRF+ +G N R K+ H+ F EIL++ P+C + K++ E +Y L VV
Sbjct: 568 QVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPE--CFIYDLSAVV 625
Query: 748 EHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 806
H G SGHYTAY + E G W H +D+ +
Sbjct: 626 MHHGKGFGSGHYTAYC---------------------YNSEG-GFWVHCNDSKLSMCTMD 663
Query: 807 KVLNSQAYLLFY 818
+V +QAY+LFY
Sbjct: 664 EVCKAQAYILFY 675
Score = 63.9 bits (154), Expect = 6e-10
Identities = 73/301 (24%), Positives = 117/301 (38%), Gaps = 75/301 (24%)
Query: 134 VVDYVRKQASITTP-KPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQI 192
+++ V Q TP P KD K+ S+NE ++ ++ K P +
Sbjct: 224 IIEIVSVQVPAQTPASPAKD---------KVLSTSENEISQKVSDSSVKRRPIVTPG--- 271
Query: 193 TVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIV--------KIEPPDLALTE 244
V GL NLGNTC+ N+V+Q LS + R+ ++ ++ + + P + T
Sbjct: 272 -VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 245 PLEIN---------------------------------LEPPGPLTLAMS------QFLN 265
++N ++P P + +S
Sbjct: 331 VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQ 390
Query: 266 EMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKA 325
M K +V+P + V + F+GY QQD+QE L LLD ++ E L+
Sbjct: 391 VMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LET 441
Query: 326 FGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLS 385
G S L + K+ K + + V+ IF G+L S + C C S E F DLS
Sbjct: 442 TGTSLPALIPTSQRKL-----IKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
Query: 386 L 386
L
Sbjct: 497 L 497
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 20/100 (20%)
Query: 24 CRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCG 83
C+H+ + L+ +L +W+ C DC T S+W CL C H CG
Sbjct: 7 CKHVGQ-LQLAQDHSSLNPQKWH-CVDCNTTE--------------SIWACLSCSHVACG 50
Query: 84 RNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV 123
R E+HALKH+ + H + L ++ V+CY+CD+ V
Sbjct: 51 RYI-EEHALKHF---QESSHPVALEVNEMYVFCYLCDDYV 86
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 749
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 750 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 809
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 810 NSQAYLLFYER 820
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 42/275 (15%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYC 126
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV +
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEV-FL 92
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
++ K + +P P + + E ES++E + K +
Sbjct: 93 EQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVAD-EGESESEDDDLKPRGLT------ 145
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 146 ---------GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP------- 186
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQELLRY 305
L + + ++E+ K+ V P L + F+GY QQD+QE LR
Sbjct: 187 --------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRC 238
Query: 306 LLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 340
L+D + E + V + ++ D + K +
Sbjct: 239 LMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.074
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 346 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 749
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 750 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 809
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 810 NSQAYLLFYER 820
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 42/275 (15%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYC 126
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV +
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEV-FL 92
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
++ K + +P P + + E ES++E + K +
Sbjct: 93 EQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVAD-EGESESEDDDLKPRGLT------ 145
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 146 ---------GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP------- 186
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQELLRY 305
L + + ++E+ K+ V P L + F+GY QQD+QE LR
Sbjct: 187 --------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRC 238
Query: 306 LLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 340
L+D + E + V + ++ D + K +
Sbjct: 239 LMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.074
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 346 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 749
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 750 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 809
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 810 NSQAYLLFYER 820
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 42/275 (15%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYC 126
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV +
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEV-FL 92
Query: 127 SSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPM 186
++ K + +P P + + E ES++E + K +
Sbjct: 93 EQRLAAPLLGSSSKFSEQDSPPPSHPLKAVPIAVAD-EGESESEDDDLKPRGLT------ 145
Query: 187 NSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPL 246
G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 146 ---------GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP------- 186
Query: 247 EINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQELLRY 305
L + + ++E+ K+ V P L + F+GY QQD+QE LR
Sbjct: 187 --------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRC 238
Query: 306 LLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 340
L+D + E + V + ++ D + K +
Sbjct: 239 LMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.074
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 346 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 388
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 8e-15
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 51/190 (26%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
S+Q L Q + E+L N C VC +R A K + + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQR-----------------APASKTLTLHTSAK 274
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEH 749
VL L LKRF N K+ K++++PE LD+ P+ ++++NT L Y LY V+ H
Sbjct: 275 VLILVLKRFSDVTGN--KIAKNVQYPECLDMQPY-------MSQQNTGPLVYVLYAVLVH 325
Query: 750 SG-TMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 808
+G + +GHY +Y KA+ +GQW+ + D V A T V
Sbjct: 326 AGWSCHNGHYFSYVKAQ-----------------------EGQWYKMDDAEVTAASITSV 362
Query: 809 LNSQAYLLFY 818
L+ QAY+LFY
Sbjct: 363 LSQQAYVLFY 372
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/236 (22%), Positives = 96/236 (40%), Gaps = 52/236 (22%)
Query: 181 KENPPMNSPCQITV-KGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
+E P++S V GL N+GNTC+ NA +Q L+ TP L + + S T + +
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHK--- 121
Query: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
G + M + V+ P + A F +Q+D+
Sbjct: 122 --------------GCMLCTMQAHITRALHNPGHVIQPSQAL------AAGFHRGKQEDA 161
Query: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 359
E L + +D M+ KA +++D K+ + + +IFG
Sbjct: 162 HEFLMFTVDAMK------------KACLPGHKQVDHHSKD-----------TTLIHQIFG 198
Query: 360 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSE 415
G S I C C +S + +LD++L + QS +++ L++ V+ E+ + E
Sbjct: 199 GYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQA-----LEQLVKPEELNGE 249
>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 8e-15
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 51/190 (26%)
Query: 631 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 690
S+Q L Q + E+L N C VC +R A K + + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQR-----------------APASKTLTLHTSAK 274
Query: 691 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEH 749
VL L LKRF N K+ K++++PE LD+ P+ ++++NT L Y LY V+ H
Sbjct: 275 VLILVLKRFSDVTGN--KIAKNVQYPECLDMQPY-------MSQQNTGPLVYVLYAVLVH 325
Query: 750 SG-TMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 808
+G + +GHY +Y KA+ +GQW+ + D V A T V
Sbjct: 326 AGWSCHNGHYFSYVKAQ-----------------------EGQWYKMDDAEVTAASITSV 362
Query: 809 LNSQAYLLFY 818
L+ QAY+LFY
Sbjct: 363 LSQQAYVLFY 372
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/243 (22%), Positives = 99/243 (40%), Gaps = 52/243 (21%)
Query: 174 EKKENMAKENPPMNSPCQITV-KGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTI 232
E ++ +E P++S V GL N+GNTC+ NA +Q L+ TP L + + S T
Sbjct: 58 EARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTC 117
Query: 233 VKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFK 292
+ + G + M + V+ P + A F
Sbjct: 118 HRHK-----------------GCMLCTMQAHITRALHNPGHVIQPSQAL------AAGFH 154
Query: 293 GYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPS 352
+Q+D+ E L + +D M+ KA +++D K+ +
Sbjct: 155 RGKQEDAHEFLMFTVDAMK------------KACLPGHKQVDHPSKD-----------TT 191
Query: 353 FVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQ 412
+ +IFGG S I C C +S + +LD++L + QS +++ L++ V+ E+
Sbjct: 192 LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQA-----LEQLVKPEEL 246
Query: 413 DSE 415
+ E
Sbjct: 247 NGE 249
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,859,064
Number of Sequences: 37866
Number of extensions: 1579360
Number of successful extensions: 10809
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 259
Number of HSP's that attempted gapping in prelim test: 8595
Number of HSP's gapped (non-prelim): 1904
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.