Search of human proteins with 49355778

Search of human proteins with 49355778

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor
5 isoform 3 [Homo sapiens]
         (702 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ...  1387   0.0  
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor...  1342   0.0  
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor...   922   0.0  
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]   416   e-116
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]        392   e-109
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...   376   e-104
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ...   374   e-103
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]       317   2e-86
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...    68   3e-11
gi|218505703 von Willebrand factor A domain containing 3A [Homo ...    50   7e-06
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    47   5e-05
gi|110578649 cache domain containing 1 [Homo sapiens]                  45   2e-04
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun...    44   5e-04
gi|118918435 von Willebrand factor A domain containing 3B [Homo ...    43   0.001
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo...    36   0.11 
gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo sa...    36   0.11 
gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo sa...    36   0.11 
gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]            36   0.11 
gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]     35   0.18 
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                 35   0.31 
gi|34452173 integrin alpha X precursor [Homo sapiens]                  33   0.90 
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          32   2.0  
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          32   2.0  
gi|215598561 enhancer of mRNA decapping 3 [Homo sapiens]               30   5.8  
gi|215598545 enhancer of mRNA decapping 3 [Homo sapiens]               30   5.8  
gi|19923613 enhancer of mRNA decapping 3 [Homo sapiens]                30   5.8  
gi|4826988 ribosomal protein L3-like [Homo sapiens]                    30   5.8  
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]               30   10.0 
gi|4504567 interferon regulatory factor 8 [Homo sapiens]               30   10.0 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    30   10.0 

>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 3 [Homo sapiens]
          Length = 702

 Score = 1387 bits (3590), Expect = 0.0
 Identities = 702/702 (100%), Positives = 702/702 (100%)

Query: 1   MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI 60
           MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI
Sbjct: 1   MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI 60

Query: 61  ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD 120
           ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD
Sbjct: 61  ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD 120

Query: 121 RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ 180
           RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ
Sbjct: 121 RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ 180

Query: 181 LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK 240
           LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK
Sbjct: 181 LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK 240

Query: 241 PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL 300
           PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL
Sbjct: 241 PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL 300

Query: 301 DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV 360
           DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV
Sbjct: 301 DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV 360

Query: 361 YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL 420
           YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL
Sbjct: 361 YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL 420

Query: 421 NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT 480
           NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT
Sbjct: 421 NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT 480

Query: 481 PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII 540
           PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII
Sbjct: 481 PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII 540

Query: 541 LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER 600
           LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER
Sbjct: 541 LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER 600

Query: 601 LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG 660
           LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG
Sbjct: 601 LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG 660

Query: 661 PLLKKPYQPRIKISKTSVRGFRREEQIFSNVMKFPFASILEL 702
           PLLKKPYQPRIKISKTSVRGFRREEQIFSNVMKFPFASILEL
Sbjct: 661 PLLKKPYQPRIKISKTSVRGFRREEQIFSNVMKFPFASILEL 702


>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 1 [Homo sapiens]
          Length = 956

 Score = 1342 bits (3474), Expect = 0.0
 Identities = 679/680 (99%), Positives = 679/680 (99%)

Query: 1   MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI 60
           MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI
Sbjct: 1   MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQRLKTKPLMTEFSVKSTI 60

Query: 61  ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD 120
           ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD
Sbjct: 61  ISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGD 120

Query: 121 RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ 180
           RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ
Sbjct: 121 RVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQ 180

Query: 181 LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK 240
           LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK
Sbjct: 181 LSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQNETFANIIFK 240

Query: 241 PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL 300
           PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL
Sbjct: 241 PTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVL 300

Query: 301 DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV 360
           DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV
Sbjct: 301 DSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKV 360

Query: 361 YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL 420
           YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL
Sbjct: 361 YIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKIL 420

Query: 421 NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT 480
           NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT
Sbjct: 421 NNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRT 480

Query: 481 PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII 540
           PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII
Sbjct: 481 PLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFII 540

Query: 541 LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER 600
           LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER
Sbjct: 541 LKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKER 600

Query: 601 LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG 660
           LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG
Sbjct: 601 LRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPG 660

Query: 661 PLLKKPYQPRIKISKTSVRG 680
           PLLKKPYQPRIKISKTSV G
Sbjct: 661 PLLKKPYQPRIKISKTSVDG 680


>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 2 [Homo sapiens]
          Length = 742

 Score =  922 bits (2382), Expect = 0.0
 Identities = 461/462 (99%), Positives = 461/462 (99%)

Query: 219 DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 278
           DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG
Sbjct: 5   DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNG 64

Query: 279 YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 338
           YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN
Sbjct: 65  YFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSN 124

Query: 339 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 398
           RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV
Sbjct: 125 RIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 184

Query: 399 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 458
           SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT
Sbjct: 185 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 244

Query: 459 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 518
           RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL
Sbjct: 245 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 304

Query: 519 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 578
           VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS
Sbjct: 305 VDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWS 364

Query: 579 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 638
           YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG
Sbjct: 365 YLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHG 424

Query: 639 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVRG 680
           MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSV G
Sbjct: 425 MSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDG 466


>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
          Length = 1313

 Score =  416 bits (1070), Expect = e-116
 Identities = 246/658 (37%), Positives = 371/658 (56%), Gaps = 31/658 (4%)

Query: 47  TKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKV 106
           TK LMT +S++ST++SRYA T V+  + N  +E  +  F + +P  AFI+NFTM I +KV
Sbjct: 33  TKLLMTSYSMRSTVVSRYAHTLVTSVLFNPHAEAHEAIFDLDLPHLAFISNFTMTINNKV 92

Query: 107 YQGEITEREKKSGDRVKEK---RNKTTEENG--EKGTEIFRASAVIPSKDKAAFFLSYEE 161
           Y  E+  +EK    ++ E+   + KT    G  ++ +E FR S  + +  +  F L+YEE
Sbjct: 93  YIAEV--KEKHQAKKIYEEAHQQGKTAAHVGIRDRESEKFRISTSLAAGTEVTFSLAYEE 150

Query: 162 LLQRRLGKYEHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSG 221
           LLQR  G+Y+  +S+RP QL  RLS++V + E  GI+ + + PL   R R +    +   
Sbjct: 151 LLQRHQGQYQLVVSLRPGQLVKRLSIEVTVSERTGISYVHIPPLRTGRLRTNAHASEVDS 210

Query: 222 PPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFV 281
           PP ST I + ET   I + PT+  Q+ I+ +GI+ DF+++YDV  E  IGD+Q+ + YF+
Sbjct: 211 PP-STRIERGETCVRITYCPTLQDQSSISGSGIMADFLVQYDVVMEDIIGDVQIYDDYFI 269

Query: 282 HYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIK 341
           HYFAP+ LPP+ KNVVFV+D S+SM GTK+ QTK A+  IL DL+  D F+II FS+ + 
Sbjct: 270 HYFAPRGLPPMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVN 329

Query: 342 VWK-DHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDR--SV 398
           VWK    I  T  ++   K Y+H M   G TD+N AL  A  +LN      G G     +
Sbjct: 330 VWKAGGSIQATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRI 389

Query: 399 SLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLT 458
            LI+FLTDG+PT G T    IL+N R+A   +V +F++  G+D DF LL +LSLEN G+ 
Sbjct: 390 PLIIFLTDGEPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIA 449

Query: 459 RRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKL 518
           RR++E+ DA  QL G Y+EI  PLL+D+R++Y    V  +   +FPNYF GSE+++AG++
Sbjct: 450 RRIYEDTDAALQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQV 509

Query: 519 VDRKLD-HLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLW 577
              K +  +H+       +  +   ++      +      G P P        + I RLW
Sbjct: 510 QPGKQELGIHLAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAP-----NVAHFIRRLW 564

Query: 578 SYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAH 637
           +Y+T  ELL +  Q+ D   +  L  +   L++ Y F+TP TS+ +    P+    E   
Sbjct: 565 AYVTIGELLDAHFQARDTTTRHLLAAKVLNLSLEYNFVTPLTSLVM--VQPKQASEETRR 622

Query: 638 GMSAAMGPE---PVVQSVRGAG---TQPGPLLK------KPYQPRIKISKTSVRGFRR 683
             S + GP+   P   S  G G    QP  + K      +P +P+  +S T+    ++
Sbjct: 623 QTSTSAGPDTIMPSSSSRHGLGVSTAQPALVPKVISPKSRPVKPKFYLSSTTTASTKK 680


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score =  392 bits (1007), Expect = e-109
 Identities = 248/647 (38%), Positives = 363/647 (56%), Gaps = 32/647 (4%)

Query: 55  SVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITER 114
           +V S + SR+A T V+ R++NRA+  Q+  FQM++P  AFITNF+M+I    Y G I E+
Sbjct: 39  TVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEK 98

Query: 115 EKK----SGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKY 170
            +     S    K K     +  G +  E F+ S  +    K  F L YEELL+RRLG Y
Sbjct: 99  AEAQAQYSAAVAKGKSAGLVKATG-RNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVY 157

Query: 171 EHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQ 230
           E  + VRPQQL   L +D++I E  GI+ LE      + Q              +    Q
Sbjct: 158 ELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVD-----------ALTTWQ 206

Query: 231 NETFANIIFKPTVVQQARIA--QNGIL-GDFIIRYDVNREQSIGDIQVLNGYFVHYFAPK 287
           N+T A+I FKPT+ QQ +    Q  +L G+ IIRYDV+R  S G IQ+ NGYFVHYFAP+
Sbjct: 207 NKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPE 266

Query: 288 DLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHL 347
            L  +PKNVVFV+D S SM G K++QT++AL  IL DL P+D+F++I FS     W+  L
Sbjct: 267 GLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSL 326

Query: 348 ISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDG 407
           +  + +++   + +   +   GGT+IN A+  A++LL+       + + SVSLI+ LTDG
Sbjct: 327 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDG 386

Query: 408 KPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDA 467
            PTVGET+   I NN REA  G+  +F +G G DV +  LEKL+L+N GL RR+HE+ D+
Sbjct: 387 DPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDS 446

Query: 468 GSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLH 527
             QL  FY E+  PLL+ +  +YP ++V + T+  F   F GSE+++AGKL DR  D L 
Sbjct: 447 ALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLT 506

Query: 528 VEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLS 587
             V+     + I  +T+  V  Q+A      SP+         N +ERLW+YLT ++LL 
Sbjct: 507 ATVSGKLPTQNITFQTESSVAEQEAEFQ---SPK-----YIFHNFMERLWAYLTIQQLLE 558

Query: 588 SWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEP 647
             + + D  +++ LR +A  L+++Y F+TP TSM +  P    D  E++      M  E 
Sbjct: 559 QTVSASD-ADQQALRNQALNLSLAYSFVTPLTSMVVTKP----DDQEQSQVAEKPMEGES 613

Query: 648 VVQSVRGAGTQPGPLLKKPYQPRIKISKTSVRGFRREEQIFSNVMKF 694
             ++V    T     L+    P+ + S +  RG+ R+     + M F
Sbjct: 614 RNRNVHSGSTFFKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNF 660


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score =  376 bits (966), Expect = e-104
 Identities = 210/586 (35%), Positives = 330/586 (56%), Gaps = 34/586 (5%)

Query: 56  VKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITERE 115
           + S + SR+A   V+ R +NRA   +++ F +++P  AFITNFT+ I    Y G + E+E
Sbjct: 50  INSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKE 109

Query: 116 ---KKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEH 172
              K+    V + +     +   +  E F  S  + +  K  F L+YEELL+R  GKYE 
Sbjct: 110 VAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEM 169

Query: 173 SISVRPQQLSGRLSVDVNILESAGIASLEV-LPLHNSRQRGSGRGEDDSGPPPSTVINQN 231
            + V+P+QL     ++V+I E  GI+ L+       +   GS   +  SG          
Sbjct: 170 YLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKK-------- 221

Query: 232 ETFANIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKD 288
               ++ FKP++ QQ        + + GDF I YDVNRE S G++Q++NGYFVH+FAP+ 
Sbjct: 222 ---GHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRE-SPGNVQIVNGYFVHFFAPQG 277

Query: 289 LPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLI 348
           LP +PKNV FV+D S SM G KL QTK+AL  IL D++ +D  + I FS  +  WK+HL+
Sbjct: 278 LPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLV 337

Query: 349 SVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 408
             TP+++++ + ++  M   G T+IN  L R I +LNK      I +RS S+++ LTDG 
Sbjct: 338 QATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGD 397

Query: 409 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAG 468
             VGE+   KI  N R A  G+  ++ +G GN++++  LE ++LEN G  RR++E+ DA 
Sbjct: 398 ANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDAD 457

Query: 469 SQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHV 528
            QL GFY+E+  PLL+ + ++YP ++++  T+  + ++++GSEI++AG+LVD  ++    
Sbjct: 458 LQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKA 517

Query: 529 EVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGD---TNHIERLWSYLTTKEL 585
           +V    +   +    +V ++  +               E D    N+IERLW+YLT ++L
Sbjct: 518 DVKGHGATNDLTFTEEVDMKEMEKALQ-----------ERDYIFGNYIERLWAYLTIEQL 566

Query: 586 LSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMD 631
           L     +  E EKE L  RA  L++ Y F+TP TSM +  P    D
Sbjct: 567 LEKRKNAHGE-EKENLTARALDLSLKYHFVTPLTSMVVTKPEDNED 611


>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
           sapiens]
          Length = 946

 Score =  374 bits (960), Expect = e-103
 Identities = 210/575 (36%), Positives = 331/575 (57%), Gaps = 28/575 (4%)

Query: 54  FSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITE 113
           + V+STI SR A T +  +++N + + Q++ F +QIP  AFI+NF+M +  K ++  I E
Sbjct: 75  YKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKE 134

Query: 114 REKKSGDRVKEKRNKTTE---ENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKY 170
           +        + +    T     +     E FR    +    K  F L Y+E+  R+LG Y
Sbjct: 135 KTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSY 194

Query: 171 EHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQ 230
           EH I ++P +L+  L VDV ++E  G+  L V          +  G  D  P    VI++
Sbjct: 195 EHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHV--------PDTFEGHFDGVP----VISK 242

Query: 231 NETFANIIFKPTVVQQARIAQN----GILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAP 286
            +  A++ FKPTV QQ RI  N     + G+ ++ YDV RE+  G+++V NGYFVH+FAP
Sbjct: 243 GQQKAHVSFKPTVAQQ-RICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAP 301

Query: 287 KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDH 346
            +L P+PKN++FV+D S SM G K++QT +A+ TIL DLR +D FS+I F+  I+ W++ 
Sbjct: 302 DNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRND 361

Query: 347 LISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTD 406
           LIS T   + D K YI  + P+GGT+IN AL RAI +LN+      +   SVSLI+ ++D
Sbjct: 362 LISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSD 421

Query: 407 GKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEED 466
           G PTVGE    KI  N +E  +  + +F++G+G DVD+  L++LS EN G+ +R++  +D
Sbjct: 422 GDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQD 481

Query: 467 AGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHL 526
             SQL  FY+++ TPLL +++ +YP +SV   T+  F NYF GSEI++AGK    KLD +
Sbjct: 482 TSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQI 541

Query: 527 HVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELL 586
              +TA+++   ++L+T   +      +D         D   D +   +LW+YLT  +LL
Sbjct: 542 ESVITATSANTQLVLET---LAQMDDLQDFLSK-----DKHADPDFTRKLWAYLTINQLL 593

Query: 587 SSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSM 621
           +    +     K R+ +    +++ +  +TP TS+
Sbjct: 594 AERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSL 628


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score =  317 bits (813), Expect = 2e-86
 Identities = 194/590 (32%), Positives = 316/590 (53%), Gaps = 37/590 (6%)

Query: 56  VKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITERE 115
           V   + SR+A   V+ +++N A+E +++ F ++IP  AFI++F +      + G+I ++ 
Sbjct: 58  VNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKV 117

Query: 116 ---KKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEH 172
              K+         N        +  E F     +  + K  F L+YEE+L+R   +YE 
Sbjct: 118 TAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEI 177

Query: 173 SISVRPQQLSGRLSVDVNILESAGIASLEV----LPLHNSRQRGSGRGEDDSGPPPSTVI 228
            I V+P+QL     +DV+I E  GI+ L+     LP   + Q          G       
Sbjct: 178 VIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKG------- 230

Query: 229 NQNETFANIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFA 285
                  +++F+PTV QQ      + + + G F + YDV+R++ I D+ V N +F H+FA
Sbjct: 231 -------HVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFA 282

Query: 286 PKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKD 345
           P++L  + KNVVFV+D S SM G K++QTK+AL  IL D++P D F ++ F  R++ WK 
Sbjct: 283 PQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKG 342

Query: 346 HLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLT 405
            L+  +  +++  + ++   S    T++NG L R I +LN+            S+++ LT
Sbjct: 343 SLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLT 402

Query: 406 DGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEE 465
           DG PT G T   +IL N R A RG+  ++ +G G++VDF  LE +S+EN G  +R++E+ 
Sbjct: 403 DGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDH 462

Query: 466 DAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDH 525
           DA  QL GFY ++  PLL D+ + YP  +V+  T+     Y+ GSEI++AG++ D K   
Sbjct: 463 DATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSS 522

Query: 526 LHVEVTA-SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKE 584
              +V A    ++F I         +K  ++          G    NH+ERLW+YLT +E
Sbjct: 523 FKADVQAHGEGQEFSITCLVDEEEMKKLLRE---------RGHMLENHVERLWAYLTIQE 573

Query: 585 LLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLE 634
           LL+  ++ D E E+  L  +A  +++ Y F+TP TSM +RG +   DGL+
Sbjct: 574 LLAKRMKVDRE-ERANLSSQALQMSLDYGFVTPLTSMSIRG-MADQDGLK 621


>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
           sapiens]
          Length = 1215

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 19/244 (7%)

Query: 297 VFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIR 356
           +F++D S+SM G  + + KDA+   L  L P   F+IIGF +  K       + + DS+ 
Sbjct: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422

Query: 357 DGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETH 415
                I  M +  GGT+I   L+  IR       H G       L+  +TDG       +
Sbjct: 423 MACDDIQRMKADMGGTNILSPLKWVIR----QPVHRG----HPRLLFVITDG----AVNN 470

Query: 416 TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFY 475
           T K+L   R  A    C ++ GIG +V  RL++ L+  + G    + E E    +++   
Sbjct: 471 TGKVLELVRNHAFSTRC-YSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529

Query: 476 DEIRTPLLSDIRID--YPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTAS 533
            +   P+LSD+ ++  +P ++ V  +     + F G  ++  G + D     LH+    S
Sbjct: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCDAS---LHISNPRS 586

Query: 534 NSKK 537
           + ++
Sbjct: 587 DKRR 590


>gi|218505703 von Willebrand factor A domain containing 3A [Homo
            sapiens]
          Length = 1184

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 15/162 (9%)

Query: 292  LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--DRFSIIGFSNRIKVWKDHLIS 349
            L   V  +LD+S SM G  L+Q K  L  ++ +   +  D F+++ F+   + W+D L+ 
Sbjct: 956  LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVE 1014

Query: 350  VTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
             T  +  +   ++ H+   G T I  AL +A                 +  +  LTDGKP
Sbjct: 1015 TTDAACHEAMQWVTHLQAQGSTSILQALLKAFSF------------HDLEGLYLLTDGKP 1062

Query: 410  TVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLS 451
                +  L  +   RE    +V   ++   +      L KL+
Sbjct: 1063 DTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 17/219 (7%)

Query: 293 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 352
           PK+VV ++D S SM G +L   K  + +IL  L   D F+II ++  +   +  L     
Sbjct: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313

Query: 353 DSIRDGK----VYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 408
            + R  K     ++  +   G   ++ AL  A  +L+ +  H+G G      I+ +TDG 
Sbjct: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDF-NHTGQGSICSQAIMLITDGA 372

Query: 409 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 467
               +T   K     R     +V IFT  IG +  F   L+ ++  N G   ++    D 
Sbjct: 373 VDTYDTIFAKYNWPDR-----KVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADV 427

Query: 468 GSQLIGFYDEIRTPLLSDIRID------YPPSSVVQATK 500
              ++ +   +  P + D   D      Y  S++ QA K
Sbjct: 428 QENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQK 466


>gi|110578649 cache domain containing 1 [Homo sapiens]
          Length = 1223

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 17/183 (9%)

Query: 291 PLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV------WK 344
           P  K++V +LD  AS+  T+L+  KDA   IL  +   D+ S++  ++ ++       +K
Sbjct: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYK 232

Query: 345 DHLISVTPDSIRDGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 403
             L   T ++ R    ++  + S    T      Q+A +L+     ++     +  +I++
Sbjct: 233 TFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIY 292

Query: 404 LTDGKPTVGETH-----TLKILNNTREAARGQVCIFTIGIGND-----VDFRLLEKLSLE 453
           L+ G  +   +      TL+++N         V I T  + ND      +   L  L+ +
Sbjct: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352

Query: 454 NCG 456
           N G
Sbjct: 353 NSG 355


>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
           [Homo sapiens]
          Length = 1137

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 42/196 (21%), Positives = 89/196 (45%), Gaps = 11/196 (5%)

Query: 293 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRI----KVWKDHLI 348
           PK++V ++D S SM G ++   K  + TIL  L   D  +II +++ +      +K  L+
Sbjct: 289 PKDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILV 348

Query: 349 SVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 408
               D+    K+ +  +   G   ++ AL+ A ++L ++   +  G      I+ ++DG 
Sbjct: 349 QADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQF-QEAKQGSLCNQAIMLISDG- 406

Query: 409 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 467
             V +   +    N  +    +V +FT  IG +V F   ++ ++  N G   ++    D 
Sbjct: 407 -AVEDYEPVFEKYNWPDC---KVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADT 462

Query: 468 GSQLIGFYDEIRTPLL 483
              ++ +   +  P++
Sbjct: 463 QENVMEYLHVLSRPMV 478


>gi|118918435 von Willebrand factor A domain containing 3B [Homo
           sapiens]
          Length = 1294

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)

Query: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHD-LRPQDRFSIIGFSNRIKVWKDHLISV 350
           L  + +++L  ++  + +KL   KD +   + + L+ + +F+ + F  +   W++ L  V
Sbjct: 504 LHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEV 563

Query: 351 TPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
             D++   + +I  +     T+   AL+ A              D+    I  LTDG+P
Sbjct: 564 NEDNLEQAQSWIRDIKIGSSTNTLSALKTAF------------ADKETQAIYLLTDGRP 610


>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
           sapiens]
          Length = 1242

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 72/326 (22%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 286 PKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRI----- 340
           P  L    + ++F+LDSS+          KDA+   +  L PQ   ++  F   +     
Sbjct: 345 PGHLGTATRELLFLLDSSSVA-------HKDAIVLAVKSLPPQTLINLAVFGTLVQPLFP 397

Query: 341 --KVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSV 398
             +   D  + +  +SI   +V      P+G  D+  AL  A+        H     +  
Sbjct: 398 ESRPCSDDAVQLICESIETLQV------PSGPPDVLAALDWAVG----QPQHRAYPRQ-- 445

Query: 399 SLIVFLTDGKPTVGETH-TLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGL 457
             +  LT   P    TH TL+++   R  AR     F+ G+G     +LL+ LS  + G 
Sbjct: 446 --LFLLTAASPMAATTHRTLELMRWHRGTAR----CFSFGLGPTCH-QLLQGLSALSRGQ 498

Query: 458 TRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQA--TKTLFPNYFNGSEIIIA 515
              +   +     L+    +   P LSDI +D+     V+A  T    P  + G +++  
Sbjct: 499 AYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEALLTPREIPALYPGDQLLGY 558

Query: 516 GKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIER 575
             L   ++D             +      V   P++A       P     G   T   E 
Sbjct: 559 CSLF--RVDGFRSRPPGGQEPGWQSSGGSVFPSPEEA-------PSAASPGTEPTGTSEP 609

Query: 576 LWSYLTTKELLSSWLQSDDEPEKERL 601
           L +   + EL S W   D E   + L
Sbjct: 610 LGTGTVSAELSSPWAARDSEQSTDAL 635


>gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo
           sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 5/156 (3%)

Query: 73  MLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVY--QGEITEREKKSGDRVKEKRNKTT 130
           M  +  E Q  E    +    ++TN   + G + +       ER +++ ++ K+K+ +  
Sbjct: 1   METKGGEGQSREVDATVEGNTYVTNVHNVFGPQNHPDSSSTPERCEETSEKPKKKKKQKP 60

Query: 131 EENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVN 190
           +E  ++ TE    S   P K K+    S EEL+   L +   S S+  ++ S   +  VN
Sbjct: 61  QEVPQEKTEDPSISFSKPKKKKS---FSKEELMSSDLEETAGSTSLLKRKKSSPKTETVN 117

Query: 191 ILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPST 226
             E AG  S+       S++     G +++    S+
Sbjct: 118 DPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS 153


>gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo
           sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 5/156 (3%)

Query: 73  MLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVY--QGEITEREKKSGDRVKEKRNKTT 130
           M  +  E Q  E    +    ++TN   + G + +       ER +++ ++ K+K+ +  
Sbjct: 1   METKGGEGQSREVDATVEGNTYVTNVHNVFGPQNHPDSSSTPERCEETSEKPKKKKKQKP 60

Query: 131 EENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVN 190
           +E  ++ TE    S   P K K+    S EEL+   L +   S S+  ++ S   +  VN
Sbjct: 61  QEVPQEKTEDPSISFSKPKKKKS---FSKEELMSSDLEETAGSTSLLKRKKSSPKTETVN 117

Query: 191 ILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPST 226
             E AG  S+       S++     G +++    S+
Sbjct: 118 DPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS 153


>gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 166

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 5/156 (3%)

Query: 73  MLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVY--QGEITEREKKSGDRVKEKRNKTT 130
           M  +  E Q  E    +    ++TN   + G + +       ER +++ ++ K+K+ +  
Sbjct: 1   METKGGEGQSREVDATVEGNTYVTNVHNVFGPQNHPDSSSTPERCEETSEKPKKKKKQKP 60

Query: 131 EENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEHSISVRPQQLSGRLSVDVN 190
           +E  ++ TE    S   P K K+    S EEL+   L +   S S+  ++ S   +  VN
Sbjct: 61  QEVPQEKTEDPSISFSKPKKKKS---FSKEELMSSDLEETAGSTSLLKRKKSSPKTETVN 117

Query: 191 ILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPST 226
             E AG  S+       S++     G +++    S+
Sbjct: 118 DPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSS 153


>gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]
          Length = 393

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 8/97 (8%)

Query: 574 ERLWSYLTTKELLSSWLQSDDEPEKERLRQRA--QALAVSYRFLT---PFTSMKLRGPVP 628
           ++ W Y    E LS    S+  P + RL +R   QALA+++   +   P T +  +GP  
Sbjct: 140 KKAWIYC---ESLSGPAPSEPTPGRGRLCRRGCVQALALAFALRSWRPPGTEVTSQGPRQ 196

Query: 629 RMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKK 665
                 +   + AA+GP+P   ++R     PG L  K
Sbjct: 197 PSSSGAKRRRLRAALGPQPTRSALRFPSASPGSLKAK 233


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 37/166 (22%), Positives = 77/166 (46%), Gaps = 19/166 (11%)

Query: 289 LPPLPKNVVFVLDSSASMVGTKLRQTKDALFTIL--HDLRPQD-RFSIIGFSNRIKV-WK 344
           LPP+P ++VF++D S S+  +  +Q KD L +++   ++ P   +  +  +S   +  W 
Sbjct: 173 LPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWD 232

Query: 345 DHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFL 404
            + +S     +      +  +   GG    G     +   N   A +G+   +  +++ +
Sbjct: 233 LNSLSTKEQVL----AAVRRLRYKGGNTFTGLALTHVLGQNLQPA-AGLRPEAAKVVILV 287

Query: 405 TDGKPTVGETHT-LKILNNTREAARGQVCIFTIGIGN--DVDFRLL 447
           TDGK +  + HT  ++L +        V +F +G+ N  + + RLL
Sbjct: 288 TDGK-SQDDVHTAARVLKDL------GVNVFAVGVKNADEAELRLL 326


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 33.1 bits (74), Expect = 0.90
 Identities = 35/157 (22%), Positives = 73/157 (46%), Gaps = 14/157 (8%)

Query: 287 KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDL-RPQDRFSIIGFSNRIK---V 342
           ++ P   +++VF++D S S+         + +  ++    RP  +FS++ FSN+ +    
Sbjct: 143 QECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPSTQFSLMQFSNKFQTHFT 202

Query: 343 WKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIV 402
           +++   S  P S+      +H +   G T    A+Q  +  L  + A  G    +  +++
Sbjct: 203 FEEFRRSSNPLSL---LASVHQLQ--GFTYTATAIQNVVHRL--FHASYGARRDAAKILI 255

Query: 403 FLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIG 439
            +TDGK   G++   K +    +AA   +  + IG+G
Sbjct: 256 VITDGKKE-GDSLDYKDVIPMADAA--GIIRYAIGVG 289


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 10/135 (7%)

Query: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--------DRFSIIGFSNRIKVW 343
           LP+   F+LD    +      Q ++ + + L D   +        D F    FS    VW
Sbjct: 251 LPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVW 310

Query: 344 KDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 403
              L +V PD++ +   + + +S +  T + G    +   L  Y     +G R + L  +
Sbjct: 311 NSQLDAVCPDTMNNPLSH-YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW 369

Query: 404 -LTDGKPTVGETHTL 417
              DG P +   HTL
Sbjct: 370 DGPDGMPVIYHGHTL 384


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 10/135 (7%)

Query: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--------DRFSIIGFSNRIKVW 343
           LP+   F+LD    +      Q ++ + + L D   +        D F    FS    VW
Sbjct: 251 LPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVW 310

Query: 344 KDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 403
              L +V PD++ +   + + +S +  T + G    +   L  Y     +G R + L  +
Sbjct: 311 NSQLDAVCPDTMNNPLSH-YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCW 369

Query: 404 -LTDGKPTVGETHTL 417
              DG P +   HTL
Sbjct: 370 DGPDGMPVIYHGHTL 384


>gi|215598561 enhancer of mRNA decapping 3 [Homo sapiens]
          Length = 508

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 116 KKSGDRVKEKRNKTTEENGEKGTEI----FRASAVIPSKDKAAFFLSYEELLQRRLGKYE 171
           KKSG +  + +NK  E  G+   EI    F     +   DKAA F   +   +RR G   
Sbjct: 175 KKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTY-ERRSGTRS 233

Query: 172 HSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHN 207
             I   P +   R   D NILES  I    ++  HN
Sbjct: 234 RGI---PNERPTRYRHDENILESEPIVYRRIIVPHN 266


>gi|215598545 enhancer of mRNA decapping 3 [Homo sapiens]
          Length = 508

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 116 KKSGDRVKEKRNKTTEENGEKGTEI----FRASAVIPSKDKAAFFLSYEELLQRRLGKYE 171
           KKSG +  + +NK  E  G+   EI    F     +   DKAA F   +   +RR G   
Sbjct: 175 KKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTY-ERRSGTRS 233

Query: 172 HSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHN 207
             I   P +   R   D NILES  I    ++  HN
Sbjct: 234 RGI---PNERPTRYRHDENILESEPIVYRRIIVPHN 266


>gi|19923613 enhancer of mRNA decapping 3 [Homo sapiens]
          Length = 508

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 116 KKSGDRVKEKRNKTTEENGEKGTEI----FRASAVIPSKDKAAFFLSYEELLQRRLGKYE 171
           KKSG +  + +NK  E  G+   EI    F     +   DKAA F   +   +RR G   
Sbjct: 175 KKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTY-ERRSGTRS 233

Query: 172 HSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHN 207
             I   P +   R   D NILES  I    ++  HN
Sbjct: 234 RGI---PNERPTRYRHDENILESEPIVYRRIIVPHN 266


>gi|4826988 ribosomal protein L3-like [Homo sapiens]
          Length = 407

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 3/81 (3%)

Query: 356 RDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGET- 414
           R  K +I  +   GGT          RL  +   HS      V  ++ +T G+   G T 
Sbjct: 174 RQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTS 233

Query: 415 --HTLKILNNTREAARGQVCI 433
             HT K+   T +  R   CI
Sbjct: 234 RWHTKKLPRKTHKGLRKVACI 254


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 13/46 (28%), Positives = 25/46 (54%)

Query: 290  PPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIG 335
            P  P  +VF LD+S  +      +T+D + +I++DL  ++    +G
Sbjct: 1753 PAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVG 1798


>gi|4504567 interferon regulatory factor 8 [Homo sapiens]
          Length = 426

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 19/51 (37%), Positives = 24/51 (47%)

Query: 102 IGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDK 152
           I   +Y G I E E+KS  R+  K     + N E    IF+A AV   K K
Sbjct: 18  IDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 200  LEVLPLHNSRQRGSGRGE-DDSGPPPSTVINQNETFANIIFKPT 242
            +EV+ + NSR RG G G  D++G  PS  +   E+ A     P+
Sbjct: 1914 VEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,913,737
Number of Sequences: 37866
Number of extensions: 1244473
Number of successful extensions: 3934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3886
Number of HSP's gapped (non-prelim): 38
length of query: 702
length of database: 18,247,518
effective HSP length: 109
effective length of query: 593
effective length of database: 14,120,124
effective search space: 8373233532
effective search space used: 8373233532
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.