Guide to the Human Genome
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Search of human proteins with 4885585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap...   691   0.0  
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap...   684   0.0  
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s...   485   e-137
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s...   485   e-137
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]             121   1e-27
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]             121   1e-27
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa...   111   1e-24
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ...   100   2e-21
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo...    91   2e-18
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]      87   3e-17
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]           58   1e-08
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]     56   5e-08
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]     56   5e-08
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]              48   1e-05
gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo...    48   1e-05
gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens]            37   0.026
gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens]            37   0.026
gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens]              37   0.026
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]     35   0.13 
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]     35   0.13 
gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]          31   1.9  
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    30   4.1  
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    30   4.1  
gi|189027141 abhydrolase domain containing 6 [Homo sapiens]            28   9.2  
gi|104526627 triadin [Homo sapiens]                                    28   9.2  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                28   9.2  

>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
           sapiens]
          Length = 346

 Score =  691 bits (1784), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300
           FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
Sbjct: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300

Query: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346
           PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
Sbjct: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346


>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
           sapiens]
          Length = 346

 Score =  684 bits (1765), Expect = 0.0
 Identities = 342/346 (98%), Positives = 343/346 (99%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGD FGYHGYTFANLGEHEFVEE+T 
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETD 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVS GVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSHGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300
           FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
Sbjct: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300

Query: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346
           PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
Sbjct: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346


>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
           sapiens]
          Length = 266

 Score =  485 bits (1248), Expect = e-137
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQ 244
           FLLQ
Sbjct: 241 FLLQ 244


>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
           sapiens]
          Length = 299

 Score =  485 bits (1248), Expect = e-137
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQ 244
           FLLQ
Sbjct: 241 FLLQ 244


>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score =  121 bits (303), Expect = 1e-27
 Identities = 105/389 (26%), Positives = 158/389 (40%), Gaps = 65/389 (16%)

Query: 9   GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           G  ++ +   Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D 
Sbjct: 45  GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
                 D  +QF +R   +G+NRAE S  R   LN  V V   T  +    E F + F  
Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLV---EDFLSGFQV 161

Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEK---------- 178
           V LT    +  ++V + CH   IK    D  G  G  F + GE   + +           
Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221

Query: 179 TKVAKVSQGVEDGPDTKRAKLDSSE----------------------------------- 203
           + V K + GV    D  R   +S +                                   
Sbjct: 222 SMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTS 281

Query: 204 ------------TTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRT 251
                          V KK+ F  +  +L          A   R    +   Q L +F  
Sbjct: 282 NFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCA 341

Query: 252 DKGRDPSSDTYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAVV 306
             GR P     E+ +EL+   +     +L  +  + L ED +R        ++AP+ A +
Sbjct: 342 QHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFI 401

Query: 307 GGILAQEIVKALSQRDPPHNNFFFFDGMK 335
           GG+ AQE++KA S +  P   + +FD ++
Sbjct: 402 GGLAAQEVMKACSGKFMPIMQWLYFDALE 430



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
           +YD Q+ ++G + Q++L   +  LVG   +G E+ KN  + G+       + + D + + 
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509

Query: 73  PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
             +   QFL R   V + +++ +    + +NP + V         DTE I    + FF  
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567

Query: 126 FDAVCLTCCSRDVIVKVDQIC 146
            D V     + D  + +D+ C
Sbjct: 568 LDGVANALDNVDARMYMDRRC 588


>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score =  121 bits (303), Expect = 1e-27
 Identities = 105/389 (26%), Positives = 158/389 (40%), Gaps = 65/389 (16%)

Query: 9   GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           G  ++ +   Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D 
Sbjct: 45  GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
                 D  +QF +R   +G+NRAE S  R   LN  V V   T  +    E F + F  
Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLV---EDFLSGFQV 161

Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEK---------- 178
           V LT    +  ++V + CH   IK    D  G  G  F + GE   + +           
Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221

Query: 179 TKVAKVSQGVEDGPDTKRAKLDSSE----------------------------------- 203
           + V K + GV    D  R   +S +                                   
Sbjct: 222 SMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTS 281

Query: 204 ------------TTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRT 251
                          V KK+ F  +  +L          A   R    +   Q L +F  
Sbjct: 282 NFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCA 341

Query: 252 DKGRDPSSDTYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAVV 306
             GR P     E+ +EL+   +     +L  +  + L ED +R        ++AP+ A +
Sbjct: 342 QHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFI 401

Query: 307 GGILAQEIVKALSQRDPPHNNFFFFDGMK 335
           GG+ AQE++KA S +  P   + +FD ++
Sbjct: 402 GGLAAQEVMKACSGKFMPIMQWLYFDALE 430



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
           +YD Q+ ++G + Q++L   +  LVG   +G E+ KN  + G+       + + D + + 
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509

Query: 73  PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
             +   QFL R   V + +++ +    + +NP + V         DTE I    + FF  
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567

Query: 126 FDAVCLTCCSRDVIVKVDQIC 146
            D V     + D  + +D+ C
Sbjct: 568 LDGVANALDNVDARMYMDRRC 588


>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
           sapiens]
          Length = 1012

 Score =  111 bits (277), Expect = 1e-24
 Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)

Query: 19  YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
           Y RQ+ + G  A +R++ +RVL+ GL+GLGAE+AKNL+L GV  LT+ D       D  A
Sbjct: 15  YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74

Query: 79  QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
           QFL+    + R+RAEAS E    LN  V V V T DI    E     F  V LT    + 
Sbjct: 75  QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131

Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189
            +KV  +CHK+ + F   D  G  G  F + GE   V++ T+   ++  ++
Sbjct: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)

Query: 17  AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
           ++YD QI ++G   Q++LR    LLVG   +G E+ K   L G+      GLT++D + +
Sbjct: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472

Query: 72  TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
              +   QFL R+  VGR +AE +   A+ LNP + V   T  ++   E     +FF++ 
Sbjct: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532

Query: 127 DAV 129
           D V
Sbjct: 533 DGV 535



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 12/36 (33%), Positives = 27/36 (75%)

Query: 299 MAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
           ++P+ A++G + AQE++KA+S++  P + + +FD +
Sbjct: 357 LSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDAL 392


>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
           sapiens]
          Length = 534

 Score =  100 bits (248), Expect = 2e-21
 Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
           +YDRQ+RLWG   Q+ L ++ V L+     G EI KNL+L G+   T++D  QV+ ED G
Sbjct: 12  KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71

Query: 78  AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
             F ++  S+G+NRAEA++E  Q LN  V    V+   E++     SFF +F  V  T  
Sbjct: 72  NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131

Query: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
                +++  +   + I       +G  GY    + EH  +E
Sbjct: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 15/167 (8%)

Query: 181 VAKVSQGVEDGPDT---KRAKLDSSETTMVKKKVVFC-PVKEALEVDW-SSEKAKAALKR 235
           VAK+ Q +   P++   K  KL  S +  ++  VV C  + E   +D  + ++  +++  
Sbjct: 361 VAKLLQSIGQAPESISEKELKLLCSNSAFLR--VVRCRSLAEEYGLDTINKDEIISSMDN 418

Query: 236 TTSD---YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLL 287
             ++   Y +L+ + +F   +GR P    Y  EED   L       L   G+S    D  
Sbjct: 419 PDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDY 478

Query: 288 PEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
             +F RY  +E   + A +GG  AQE++K ++++    NN + + GM
Sbjct: 479 VHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 525


>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
           sapiens]
          Length = 528

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%)

Query: 22  QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
           + RLWG   Q+ L ++ V L+     G EI KNL+L G+   T++D  QV+ ED G  F 
Sbjct: 10  EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69

Query: 82  IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
           ++  S+G+NRAEA++E  Q LN  V    V+   E++     SFF +F  V  T      
Sbjct: 70  LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129

Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
            +++  +   + I       +G  GY    + EH  +E
Sbjct: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 15/167 (8%)

Query: 181 VAKVSQGVEDGPDT---KRAKLDSSETTMVKKKVVFC-PVKEALEVDW-SSEKAKAALKR 235
           VAK+ Q +   P++   K  KL  S +  ++  VV C  + E   +D  + ++  +++  
Sbjct: 355 VAKLLQSIGQAPESISEKELKLLCSNSAFLR--VVRCRSLAEEYGLDTINKDEIISSMDN 412

Query: 236 TTSD---YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLL 287
             ++   Y +L+ + +F   +GR P    Y  EED   L       L   G+S    D  
Sbjct: 413 PDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDY 472

Query: 288 PEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
             +F RY  +E   + A +GG  AQE++K ++++    NN + + GM
Sbjct: 473 VHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 519


>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
          Length = 1052

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 60/172 (34%), Positives = 85/172 (49%), Gaps = 5/172 (2%)

Query: 13  EEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVT 72
           E + A Y RQ  + G  A +++  S V L G+ GLG EIAKNL+LAG+K +T+ D E+  
Sbjct: 38  EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97

Query: 73  PEDPGAQFLIRTGSV--GRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-SFFTQFDAV 129
             D G  F +    V   RNRAEA L+    LNP V V   +    +  + SF  ++  V
Sbjct: 98  AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157

Query: 130 CLTCCSRDVIVKVDQICHKN--SIKFFTGDVFGYHGYTFANLGEHEFVEEKT 179
            LT     +  K++  C      IKF + DV G     F + G+   V + T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTT 209



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 34/131 (25%), Positives = 67/131 (51%), Gaps = 15/131 (11%)

Query: 218 EALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVL 277
           + L VD+S+ +A   +      +  +  L +F+    R P+    ++DSE LL++   + 
Sbjct: 310 KCLIVDFSNPEAPLEI------HTAMLALDQFQEKYSRKPNVGC-QQDSEELLKLATSIS 362

Query: 278 DSLGISPDLLPEDFVRYCF----SEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDG 333
           ++L   PD+   D V +        ++P+ A VGG+ +QE++KA++ +  P   + +   
Sbjct: 363 ETLEEKPDV-NADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLY--- 418

Query: 334 MKGNGIVECLG 344
           ++   IVE LG
Sbjct: 419 LEAADIVESLG 429



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 31/145 (21%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGV-----KG-LTMLDHEQVTPEDPGAQFLIRTG 85
           ++L+   + LVG   +G E+ KN  L GV     KG +T+ D + +   +   QFL R  
Sbjct: 456 QKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPH 515

Query: 86  SVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPES-----FFTQFDAVCLTCCSRDVIV 140
            + + ++  + +    +N  + +      +    E+     F+T+ D +     + +   
Sbjct: 516 HIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARR 575

Query: 141 KVDQICHKNSIKFFTGDVFGYHGYT 165
            VD  C  N          G  G+T
Sbjct: 576 YVDSRCLANLRPLLDSGTMGTKGHT 600


>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
          Length = 640

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 4/138 (2%)

Query: 29  EAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVG 88
           E  + +   RVL+VG  G+G E+ KNL+L G   + ++D + +   +   QFL +   VG
Sbjct: 10  ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVG 69

Query: 89  RNRAEASLERAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQI 145
           R++A+ + E      P  ++ V   D    P+    FF QF  V     +R     V+++
Sbjct: 70  RSKAQVAKESVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRM 128

Query: 146 CHKNSIKFFTGDVFGYHG 163
           C    +        GY G
Sbjct: 129 CLAADVPLIESGTAGYLG 146


>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
          Length = 449

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%)

Query: 34  LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93
           L   +VL++G  GLG E+ KNL L+G + + ++D + +   +   QFL R   +GR +AE
Sbjct: 53  LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 112

Query: 94  ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140
            + E   +  P  +V      I+   ++F+ QF  +    C  D I+
Sbjct: 113 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 156


>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
          Length = 463

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%)

Query: 34  LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93
           L   +VL++G  GLG E+ KNL L+G + + ++D + +   +   QFL R   +GR +AE
Sbjct: 67  LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126

Query: 94  ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140
            + E   +  P  +V      I+   ++F+ QF  +    C  D I+
Sbjct: 127 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 170


>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
          Length = 460

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 2/99 (2%)

Query: 11  ISEEEAAQYDRQIRL--WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           +S +E  +Y RQ+ L   G+  Q RL  + VL+VG  GLG  +A+ L  AGV  L ++D+
Sbjct: 55  LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVD 107
           + V   +   Q L      G+ +A ++    + LN  V+
Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVE 153


>gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo
           sapiens]
          Length = 445

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 15/167 (8%)

Query: 181 VAKVSQGVEDGPDT---KRAKLDSSETTMVKKKVVFC-PVKEALEVDW-SSEKAKAALKR 235
           VAK+ Q +   P++   K  KL  S +  ++  VV C  + E   +D  + ++  +++  
Sbjct: 272 VAKLLQSIGQAPESISEKELKLLCSNSAFLR--VVRCRSLAEEYGLDTINKDEIISSMDN 329

Query: 236 TTSD---YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLL 287
             ++   Y +L+ + +F   +GR P    Y  EED   L       L   G+S    D  
Sbjct: 330 PDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDY 389

Query: 288 PEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
             +F RY  +E   + A +GG  AQE++K ++++    NN + + GM
Sbjct: 390 VHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 436


>gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens]
          Length = 623

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 318 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 377

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 378 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 434

Query: 155 TGD 157
             D
Sbjct: 435 LMD 437


>gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens]
          Length = 676

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473

Query: 155 TGD 157
             D
Sbjct: 474 LMD 476


>gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens]
          Length = 703

 Score = 37.0 bits (84), Expect = 0.026
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473

Query: 155 TGD 157
             D
Sbjct: 474 LMD 476


>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
          Length = 348

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
           +++R   V +VG+ G+G+  A+ L   G+  L + D+++V   +    F  +    G ++
Sbjct: 13  EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 71

Query: 92  AEASLERAQNLNPMVDVKVDTEDI 115
            +A+    +N+NP V  +V   +I
Sbjct: 72  VQAAEHTLRNINPDVLFEVHNYNI 95


>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
          Length = 404

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
           +++R   V +VG+ G+G+  A+ L   G+  L + D+++V   +    F  +    G ++
Sbjct: 69  EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127

Query: 92  AEASLERAQNLNPMVDVKVDTEDI 115
            +A+    +N+NP V  +V   +I
Sbjct: 128 VQAAEHTLRNINPDVLFEVHNYNI 151


>gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
          Length = 535

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 168 NLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEV-DWSS 226
           NL E + V       +++Q +EDGP  +R K+  +    V K     PV   LE   W S
Sbjct: 137 NLSEQDIVSSDLAYLRLAQHLEDGP--RRVKVSHAFLPRVPKVQSNGPVSICLEAGTWRS 194

Query: 227 -EKAKAALK 234
            EKA AA++
Sbjct: 195 LEKATAAIQ 203


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 175 VEEKTKVAKVSQGV--EDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAA 232
           VEEK K  K    +  ED    K   +D+S T++ K K    P  E  +++ +  + + +
Sbjct: 215 VEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMK-RSRPTSEGSDIESTEPQKQCS 273

Query: 233 LKRTTSDYFLLQVLLKFRTDKGRDPSSDTYE 263
            K+   D      L + RT K +  SS+  E
Sbjct: 274 KKKKKRDRVEASSLPEVRTGKRKRSSSEDAE 304


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 175 VEEKTKVAKVSQGV--EDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAA 232
           VEEK K  K    +  ED    K   +D+S T++ K K    P  E  +++ +  + + +
Sbjct: 215 VEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMK-RSRPTSEGSDIESTEPQKQCS 273

Query: 233 LKRTTSDYFLLQVLLKFRTDKGRDPSSDTYE 263
            K+   D      L + RT K +  SS+  E
Sbjct: 274 KKKKKRDRVEASSLPEVRTGKRKRSSSEDAE 304


>gi|189027141 abhydrolase domain containing 6 [Homo sapiens]
          Length = 337

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 10/77 (12%)

Query: 257 PSSDTYEEDSELLLQIR----NDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQ 312
           P+   Y  D++ + +++    +  ++ + + P   PE+      SEM  +C+ V   + Q
Sbjct: 173 PAGLQYSTDNQFVQRLKELQGSAAVEKIPLIPST-PEEM-----SEMLQLCSYVRFKVPQ 226

Query: 313 EIVKALSQRDPPHNNFF 329
           +I++ L     PHNNF+
Sbjct: 227 QILQGLVDVRIPHNNFY 243


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 14/36 (38%), Positives = 23/36 (63%)

Query: 175 VEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 210
           V +  K A+VS+ VED P +K+AK  + + +  K+K
Sbjct: 648 VTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQK 683


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 28.5 bits (62), Expect = 9.2
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 256 DPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIV 315
           D SS   +ED E + Q   +++D+  + PD      VRY  S+       +G   +QE V
Sbjct: 44  DTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRY--SDRPTTAFELGLFGSQEEV 101

Query: 316 KALSQR 321
           KA ++R
Sbjct: 102 KAAARR 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,878,216
Number of Sequences: 37866
Number of extensions: 540967
Number of successful extensions: 1532
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1489
Number of HSP's gapped (non-prelim): 40
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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