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Search of human proteins with 48762709
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48762709 SAM domain, SH3 domain and nuclear localization
signals, 1 [Homo sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48762709 SAM domain, SH3 domain and nuclear localization sign... 753 0.0
gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens] 263 2e-70
gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens] 257 1e-68
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 46 5e-05
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 45 8e-05
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 45 8e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 7e-04
gi|55956916 myosin IE [Homo sapiens] 42 7e-04
gi|11321634 CD2-associated protein [Homo sapiens] 42 9e-04
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 40 0.003
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 40 0.003
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 40 0.003
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 40 0.003
gi|24415404 MDN1, midasin homolog [Homo sapiens] 40 0.004
gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a ... 39 0.006
gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens] 39 0.006
gi|50511947 cajalin 2 isoform b [Homo sapiens] 39 0.010
gi|50511945 cajalin 2 isoform a [Homo sapiens] 39 0.010
gi|10047134 cajalin 2 isoform c [Homo sapiens] 39 0.010
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 38 0.013
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 38 0.013
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap... 38 0.017
gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo sap... 38 0.017
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 37 0.022
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 37 0.022
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 37 0.022
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 37 0.022
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ... 37 0.022
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 37 0.022
gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens] 37 0.022
>gi|48762709 SAM domain, SH3 domain and nuclear localization
signals, 1 [Homo sapiens]
Length = 373
Score = 753 bits (1944), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MLKRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTS 60
MLKRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTS
Sbjct: 1 MLKRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTS 60
Query: 61 NNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSL 120
NNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSL
Sbjct: 61 NNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSL 120
Query: 121 KASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYD 180
KASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYD
Sbjct: 121 KASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYD 180
Query: 181 TDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKIKANRRSNS 240
TDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKIKANRRSNS
Sbjct: 181 TDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKIKANRRSNS 240
Query: 241 KKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAE 300
KKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAE
Sbjct: 241 KKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAE 300
Query: 301 NFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGKEDLESENLS 360
NFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGKEDLESENLS
Sbjct: 301 NFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGKEDLESENLS 360
Query: 361 DMVHKIIITEPSD 373
DMVHKIIITEPSD
Sbjct: 361 DMVHKIIITEPSD 373
>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
Length = 1247
Score = 263 bits (671), Expect = 2e-70
Identities = 156/346 (45%), Positives = 216/346 (62%), Gaps = 25/346 (7%)
Query: 20 RSSSFGNFDRFRNNSLSKPDDSTE--AHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTM 77
R+ SFG FD N SL ++++ EGD +S T++ LGKK++++ TM
Sbjct: 404 RTCSFGGFD-LTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPTASRIS-LGKKVKSVKETM 461
Query: 78 KKKVGKKYIKALSEEKDEEDG-ENAHPYRNSDPVIGTHTEKVSLKASDSMDSL---YSGQ 133
+K++ KKY ++SE+ DG + P DP H +K LKA S++SL SGQ
Sbjct: 462 RKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDP---EHLDKPKLKAGGSVESLRSSLSGQ 518
Query: 134 SSSSG--ITSCSDGTSNRDSFRLDD----DGPYSGPFCGRARVHTDFTPSPYDTDSLKIK 187
SS SG +++ TSNR+S + +D + PY GPFCGRARVHTDFTPSPYDTDSLK+K
Sbjct: 519 SSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLK 578
Query: 188 KGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKK-IKANRRSNSKKSKTL 246
KGDIIDII K PMG W G+LNNKVG FKFIYVDV+SE+E PK+ + R+ + K++
Sbjct: 579 KGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSV 638
Query: 247 QEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEE 306
++ L+RI+L+E+ T L NGYE L+ K ++E L ELNI +P+ R LL+A E
Sbjct: 639 EDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAV------E 692
Query: 307 IIQEQENEPEPLSLSSDISLNKSQLDDC-PRDSGCYISSGNSDNGK 351
++QE ++ + + ++ L C PRDSGCY SS N +NGK
Sbjct: 693 LLQEYDSNSDQSGSQEKLLVDSQGLSGCSPRDSGCYESSENLENGK 738
Score = 30.8 bits (68), Expect = 2.1
Identities = 19/58 (32%), Positives = 28/58 (48%)
Query: 245 TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENF 302
++ ++L I L Y TL G+ TL + + + L E I R+LLSAA F
Sbjct: 1181 SVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLF 1238
>gi|9506363 SAM and SH3 domain containing 3 [Homo sapiens]
Length = 380
Score = 257 bits (656), Expect = 1e-68
Identities = 166/369 (44%), Positives = 221/369 (59%), Gaps = 20/369 (5%)
Query: 1 MLKRKPSNVSEKEKHQKPK----RSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQ 56
ML+RKPSN SEKE QK K RSSSF +F + + +S + + P + SG
Sbjct: 1 MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVP 60
Query: 57 SK--TSNNGGGLGKKMRA-ISWTMKKKVGKKYIKALSEEKDE--EDGENAHPYRNSDPVI 111
+ +G LGKK RA IS TM +K+GK +KALSEE + E+G +A P +
Sbjct: 61 TPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEG-SASPTSPDYSLD 119
Query: 112 GTHTEKVSLKASDSMDSLYS--GQSSSSGITSCSDGTSNRDSFRLDDDGP-YSGPFCGRA 168
EK++L S+ + + +S+G CS + SF + P Y+GPFCGRA
Sbjct: 120 SPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGS-GSFGEEPPAPQYTGPFCGRA 178
Query: 169 RVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAA 228
RVHTDFTPSPYD DSLK++KGD+I II K P+G W G+LN KVG+FKFIYVDV+ EE
Sbjct: 179 RVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVG 238
Query: 229 PKKIKANRRSNSK--KSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNI 286
+ + R+S K K KTL E LERI L+E+TSTLLLNGY+TLED K+++E+HL ELNI
Sbjct: 239 HAR-PSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNI 297
Query: 287 ENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGN 346
+P R +LL+AAE L+ + E+ E S D PRDSGC+
Sbjct: 298 MDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCF---EG 354
Query: 347 SDNGKEDLE 355
S++G++D E
Sbjct: 355 SESGRDDAE 363
>gi|140161500 ankyrin repeat and sterile alpha motif domain
containing 1 [Homo sapiens]
Length = 1134
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/74 (35%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Query: 244 KTLQEFLERIHLQEYTSTLLLNGYETLEDLKD--IKESHLIELNIENPDDRRRLLSAAEN 301
+++ E+LE I LQ+Y S LLLNG++ + L ++E L ++ I +P RR+LL AA +
Sbjct: 699 QSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARS 758
Query: 302 FLEEEIIQEQENEP 315
+ + + N P
Sbjct: 759 LPKVKALGYDGNSP 772
Score = 34.7 bits (78), Expect = 0.14
Identities = 27/117 (23%), Positives = 57/117 (48%), Gaps = 12/117 (10%)
Query: 245 TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIE-LNIENPDDRRRLLSAAENFL 303
++ +L+ + LQ+Y + L +GY +++ +K++ E L+ L ++ R+R++++ L
Sbjct: 774 SVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIAS----L 829
Query: 304 EEEIIQEQENEPEPLS------LSSDISLNKSQLDDCP-RDSGCYISSGNSDNGKED 353
+ +E +P S L S S SQ D C R + + G++ + D
Sbjct: 830 ADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHD 886
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 45.4 bits (106), Expect = 8e-05
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 167 RARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEE 225
R R F+ P + D L++K GDII+++ + G W G+LN K G F ++ +S E
Sbjct: 63 RRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGE 121
Score = 33.5 bits (75), Expect = 0.32
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 9/63 (14%)
Query: 178 PYDT---DSLKIKKGDIIDIICK--TPMGMWTGMLNNKVGNFKFIYVDVI----SEEEAA 228
PY+ D L IK+GDI+ +I K +G W G LN + G F +V ++ +E
Sbjct: 240 PYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNR 299
Query: 229 PKK 231
PKK
Sbjct: 300 PKK 302
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 45.4 bits (106), Expect = 8e-05
Identities = 21/59 (35%), Positives = 33/59 (55%)
Query: 167 RARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEE 225
R R F+ P + D L++K GDII+++ + G W G+LN K G F ++ +S E
Sbjct: 100 RRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGE 158
Score = 38.5 bits (88), Expect = 0.010
Identities = 44/182 (24%), Positives = 74/182 (40%), Gaps = 13/182 (7%)
Query: 182 DSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEE--------EAAPKKIK 233
D L I G+II I K G W G +N + G F +V I +E +A K +
Sbjct: 16 DELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMKKDPLTNKAPEKPLH 75
Query: 234 ANRRSNS-KKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDD- 291
NS S+T+ +R + + + +D ++K +IE+ E +
Sbjct: 76 EVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGW 135
Query: 292 RRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGK 351
+L+ I+E E + L +S D L+KS L + +G G+S + K
Sbjct: 136 WEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSSLRE---TTGSESDGGDSSSTK 192
Query: 352 ED 353
+
Sbjct: 193 SE 194
Score = 33.5 bits (75), Expect = 0.32
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 9/63 (14%)
Query: 178 PYDT---DSLKIKKGDIIDIICK--TPMGMWTGMLNNKVGNFKFIYVDVI----SEEEAA 228
PY+ D L IK+GDI+ +I K +G W G LN + G F +V ++ +E
Sbjct: 277 PYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNR 336
Query: 229 PKK 231
PKK
Sbjct: 337 PKK 339
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 42.4 bits (98), Expect = 7e-04
Identities = 37/156 (23%), Positives = 60/156 (38%), Gaps = 1/156 (0%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
S+ S K K S + D ++S S DS++ + ++ S S +S++
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
+ S SE D D ++ +SD ++ S +SDS
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735
Query: 127 DSLYSGQSS-SSGITSCSDGTSNRDSFRLDDDGPYS 161
DS S SS SS ++ SD + + DS D S
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771
Score = 42.0 bits (97), Expect = 9e-04
Identities = 74/373 (19%), Positives = 134/373 (35%), Gaps = 35/373 (9%)
Query: 7 SNVSEKEKHQKPKRSSSFG----NFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNN 62
SN ++ + SSS G N D ++N DS A + D + S + SN
Sbjct: 471 SNGNDDANSESDNNSSSRGDASYNSDESKDNG--NGSDSKGAEDDDSDSTSDTNNSDSNG 528
Query: 63 GGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKA 122
G G S + K K S+ D + ++++ +SD ++ S
Sbjct: 529 NGNNGNDDNDKSDSGKGK---------SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579
Query: 123 SDS--MDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYD 180
SDS DS S S SS ++ SD + + DS D S ++ +D + S
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK 639
Query: 181 TDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKIKANRRSNS 240
+DS D D + + ++ + S+ ++ ++ S+S
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-------SDSSSSSDSSNSSDSSDS 692
Query: 241 KKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAE 300
S E + + S+ D D S+ + + N D ++++
Sbjct: 693 SDSSNSSESSDSSDSSDSDSS----------DSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 301 NFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGKEDLESENLS 360
+ + ++ S +S S + S D DS S +S N + +S N S
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD-SSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 361 DMVHKIIITEPSD 373
D + ++ SD
Sbjct: 802 DSSNSSDSSDSSD 814
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/155 (22%), Positives = 59/155 (38%), Gaps = 4/155 (2%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
S+ S+ RS S + D ++ S DS+++ + + ++ S + S +SN+
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
S SE + D N+ NS + S +S+S
Sbjct: 905 SSD----SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 127 DSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYS 161
DS S SS S + SD +++ DS D S
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995
Score = 38.1 bits (87), Expect = 0.013
Identities = 30/128 (23%), Positives = 50/128 (39%)
Query: 21 SSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTMKKK 80
S S + D ++ S DS+++ + ++ S + S +S++ + S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Query: 81 VGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSLYSGQSSSSGIT 140
SE D D N+ +S + S +SDS DS S SS S +
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 141 SCSDGTSN 148
S S +SN
Sbjct: 1133 SDSSDSSN 1140
Score = 36.2 bits (82), Expect = 0.049
Identities = 38/178 (21%), Positives = 63/178 (35%), Gaps = 21/178 (11%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
S+ S+ SS N ++S S DS+++ + +N S S S++
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
S+ D D N+ +S + S +SDS
Sbjct: 738 SNS--------------------SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 127 DSLYSGQSS-SSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYDTDS 183
DS S S+ SS + SD +++ DS D S + +D + S +DS
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Score = 36.2 bits (82), Expect = 0.049
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 1/155 (0%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
SN S+ S + +R +++ S DS+++ ++ S + +++SN+
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
+ S + + S D + N+ NS + S +S+S
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 127 DSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYS 161
DS S SS+S +S S+ + + DS D S
Sbjct: 955 DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Score = 35.4 bits (80), Expect = 0.083
Identities = 32/142 (22%), Positives = 54/142 (38%), Gaps = 1/142 (0%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
SN S+ S S + + ++ S DS+E+ + S + S +S++
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
+ S + + S D D N+ +S + S +SDS
Sbjct: 949 DSSNSSDS-SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 127 DSLYSGQSSSSGITSCSDGTSN 148
DS S SS+S +S S +SN
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSN 1029
Score = 34.7 bits (78), Expect = 0.14
Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 24/142 (16%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGL 66
SN S+ SS N N+S S +S+++ + ++ S + S +S++
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 67 GKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSM 126
+ S S+ D D N+ NS S +SDS
Sbjct: 999 DSSNSSDS---------------SDSSDSSDSSNSSDSSNSSD---------SSNSSDSS 1034
Query: 127 DSLYSGQSSSSGITSCSDGTSN 148
DS S SS S +S S +SN
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSN 1056
Score = 33.5 bits (75), Expect = 0.32
Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 8/153 (5%)
Query: 4 RKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPD----DSTEAHEGDPTNGSGEQSKT 59
+ S+ S+ SS + D +NS S D DS+++ + D ++ S +
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 60 SNNGGGLGKKMRAISWTMKKKVGKKYIKALSEEK-DEEDGENAHPYRNSDPVIGTHTEKV 118
++ S + + + S+ K D D ++ NSD +++
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 119 SLKASDSMDSLYSGQSSSSGITSCSDGTSNRDS 151
S +SDS DS S SSSS ++ SD + + DS
Sbjct: 666 S-DSSDSSDS--SDSSSSSDSSNSSDSSDSSDS 695
Score = 32.7 bits (73), Expect = 0.54
Identities = 33/159 (20%), Positives = 57/159 (35%), Gaps = 5/159 (3%)
Query: 3 KRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLS--KPDDSTEAHEGDPTNGSGEQSKTS 60
K +P N S + ++D F + S+ P+ S E++ D N + + +S
Sbjct: 429 KSEPGNKVGHSNTGSDSNSDGYDSYD-FDDKSMQGDDPNSSDESNGNDDANSESDNNSSS 487
Query: 61 NNGGGLGKKMRAISWTMKKKVGKKY--IKALSEEKDEEDGENAHPYRNSDPVIGTHTEKV 118
+ G + + S+ + + N + + + + K
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547
Query: 119 SLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDD 157
SDS DS S SS S + SD S+ DS D D
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD 586
Score = 32.7 bits (73), Expect = 0.54
Identities = 36/185 (19%), Positives = 71/185 (38%), Gaps = 17/185 (9%)
Query: 7 SNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTN--------GSGEQSK 58
S+ S+ + S+S + D ++ S DS++ + D +N S + S
Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Query: 59 TSNNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKV 118
+SN+ S S+ + D +++ +SD +++
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDS---------SDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 119 SLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSP 178
S ++ S +S S S+SS + SD +++ DS D S + +D + S
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 179 YDTDS 183
+DS
Sbjct: 984 DSSDS 988
Score = 32.3 bits (72), Expect = 0.71
Identities = 27/128 (21%), Positives = 52/128 (40%)
Query: 21 SSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTMKKK 80
S+S + D ++ S +S+++ + ++ S + S +S++ + S
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 81 VGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSLYSGQSSSSGIT 140
S+ D D ++ +S + S +SDS DS S +SS S +
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240
Query: 141 SCSDGTSN 148
S S +SN
Sbjct: 1241 SDSSDSSN 1248
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 42.4 bits (98), Expect = 7e-04
Identities = 22/43 (51%), Positives = 23/43 (53%)
Query: 180 DTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVI 222
DTD L DIIDII + P G WTG L K G F YV I
Sbjct: 1066 DTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 42.0 bits (97), Expect = 9e-04
Identities = 20/42 (47%), Positives = 27/42 (64%)
Query: 178 PYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYV 219
P + D L++K GDIIDI + G W+G LNNK+G F +V
Sbjct: 121 PQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFV 162
Score = 31.2 bits (69), Expect = 1.6
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 182 DSLKIKKGDIIDIICKTP--MGMWTGMLNNKVGNFK---FIYVDVISEEEAAPKK 231
D L K+G+II +I K G W G LN K G F + ++ + ++ PKK
Sbjct: 286 DELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKK 340
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 12/81 (14%)
Query: 154 LDDDGPYSGPFCGRARVH------------TDFTPSPYDTDSLKIKKGDIIDIICKTPMG 201
L G P C R R H +F+ SP D LK++ G+I+++I + G
Sbjct: 60 LRGSGEARRPRCARRRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIEDG 119
Query: 202 MWTGMLNNKVGNFKFIYVDVI 222
W G N ++G F +V+++
Sbjct: 120 WWLGKKNGQLGAFPSNFVELL 140
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 40.4 bits (93), Expect = 0.003
Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 123 SDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYDTD 182
S S+ + + Q++ G S + R S ++ S +AR + T + D
Sbjct: 122 SSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQT----NED 177
Query: 183 SLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVI--SEEEAAPKKIKANRRSNS 240
L + KGDII + G W G LN + G F YV I SE +PK +K +
Sbjct: 178 ELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPL 237
Query: 241 KKSKTLQEFLERIHLQEYTSTLLLNGYET----LEDLKDIKESHLIELNIENPDDRRRLL 296
K+ Y + +L N +T ++L+ + ++L L N +
Sbjct: 238 TKN--------------YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVT 283
Query: 297 SAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDC 334
S NF EE+ Q+ + L S N+ ++ C
Sbjct: 284 SLLGNF--EEVCTFQQTLCQALEECSKFPENQHKVGGC 319
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 18/164 (10%)
Query: 3 KRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSK---------PDDSTEAHEGDPTNGS 53
KRK +KE+ ++ N + F + + P+ TE T
Sbjct: 1483 KRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTI 1542
Query: 54 GEQSKTSNNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGT 113
G + + G GK+ I+ T K+ +K ++ E + ++ P S P
Sbjct: 1543 GISATWTTLAGSHGKRNNTITTTSSKRKNRK--NKITPENVQIIFDDPLPISYSQP---- 1596
Query: 114 HTEKVSLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDD 157
EKV+ ++ S S SG S + I+SCSD +SN +S R D+
Sbjct: 1597 --EKVNGESKSSSTS-ESGDSDNMRISSCSDESSNSNSSRKSDN 1637
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 18/164 (10%)
Query: 3 KRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSK---------PDDSTEAHEGDPTNGS 53
KRK +KE+ ++ N + F + + P+ TE T
Sbjct: 1232 KRKEKRRKKKEEQRRKLEEIEAKNKENFELQAAQEKEKLKVEDEPEVLTEPPSATTTTTI 1291
Query: 54 GEQSKTSNNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGT 113
G + + G GK+ I+ T K+ +K ++ E + ++ P S P
Sbjct: 1292 GISATWTTLAGSHGKRNNTITTTSSKRKNRK--NKITPENVQIIFDDPLPISYSQP---- 1345
Query: 114 HTEKVSLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDD 157
EKV+ ++ S S SG S + I+SCSD +SN +S R D+
Sbjct: 1346 --EKVNGESKSSSTS-ESGDSDNMRISSCSDESSNSNSSRKSDN 1386
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 20/175 (11%)
Query: 11 EKEKHQKPKRSSSFGNFDRFRNNSLSKPDD-STEAHEGDPTNGSGEQSKTSNNGGGLGKK 69
EK+K +S G +N++ +D + H+G+ + K+ + GG L K
Sbjct: 4708 EKDKEDPDSKSDIKGE-----DNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKH 4762
Query: 70 MRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSL 129
M ++ K+ ++ EE+DEE+ +N + + G E L A D D+L
Sbjct: 4763 MGDLNGEEADKLDERLWGDDDEEEDEEEEDN----KTEETGPGMDEEDSELVAKD--DNL 4816
Query: 130 YSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYDTDSL 184
SG S+ S D ++ DD G G +++ YD + +
Sbjct: 4817 DSGNSNKD--KSQQDKKEEKEEAEADDGGQ------GEDKINEQIDERDYDENEV 4863
>gi|41327712 v-crk sarcoma virus CT10 oncogene homolog isoform a
[Homo sapiens]
Length = 304
Score = 39.3 bits (90), Expect = 0.006
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 5/137 (3%)
Query: 92 EKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSLYSGQSSSSG---ITSCSDGTSN 148
+K EE NA +I + AS S+ +L G S + G
Sbjct: 163 DKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYA 222
Query: 149 RDSFRLDDDGPYSGPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLN 208
+ S +GP ARV P+ YD +L ++ G+++ + G W G N
Sbjct: 223 QPSVNTPLPNLQNGPIY--ARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECN 280
Query: 209 NKVGNFKFIYVDVISEE 225
K G+F F +V ++ ++
Sbjct: 281 GKRGHFPFTHVRLLDQQ 297
>gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]
Length = 173
Score = 39.3 bits (90), Expect = 0.006
Identities = 19/59 (32%), Positives = 32/59 (54%)
Query: 248 EFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEE 306
E+L+ + L +Y + + NGY+ LE K I + L + + P RRR+L A E++
Sbjct: 8 EWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVRRLREQD 66
>gi|50511947 cajalin 2 isoform b [Homo sapiens]
Length = 510
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 245 TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIE-LNIENPDDRRRLLSAAENFL 303
++ E+L+ I L +YT L+NGY +++ LK I E LI L I R+R+L++ + L
Sbjct: 114 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRL 173
Query: 304 EEE 306
++
Sbjct: 174 HDD 176
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/59 (28%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 244 KTLQEFLERIHLQEYTSTLLLNGYETLEDLKD--IKESHLIELNIENPDDRRRLLSAAE 300
+T+ ++LE I L +Y + L+ NG++ ++ + +++ L+E+ I N R+R+L A +
Sbjct: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 245 TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIE-LNIENPDDRRRLLSAAENFL 303
++ E+L+ I L +YT L+NGY +++ LK I E LI L I R+R+L++ + L
Sbjct: 888 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRL 947
Query: 304 EEE 306
++
Sbjct: 948 HDD 950
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/59 (28%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 244 KTLQEFLERIHLQEYTSTLLLNGYETLEDLKD--IKESHLIELNIENPDDRRRLLSAAE 300
+T+ ++LE I L +Y + L+ NG++ ++ + +++ L+E+ I N R+R+L A +
Sbjct: 813 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 871
>gi|10047134 cajalin 2 isoform c [Homo sapiens]
Length = 414
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/63 (34%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Query: 245 TLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIE-LNIENPDDRRRLLSAAENFL 303
++ E+L+ I L +YT L+NGY +++ LK I E LI L I R+R+L++ + L
Sbjct: 114 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRL 173
Query: 304 EEE 306
++
Sbjct: 174 HDD 176
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/59 (28%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 244 KTLQEFLERIHLQEYTSTLLLNGYETLEDLKD--IKESHLIELNIENPDDRRRLLSAAE 300
+T+ ++LE I L +Y + L+ NG++ ++ + +++ L+E+ I N R+R+L A +
Sbjct: 39 QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 38.1 bits (87), Expect = 0.013
Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
Query: 268 ETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLN 327
E++ ++D++ LI+L + N D + ++ EN ++E E E E + + + S N
Sbjct: 995 ESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGEN------LEEDEEEEEGGAETEEQSGN 1048
Query: 328 KSQLDDCPRDSGCYISSGNSDNGKEDLESEN 358
+S++++ + G S N D+ E+ E EN
Sbjct: 1049 ESEVNEPEEEEG----SDNDDDEGEEEEEEN 1075
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 38.1 bits (87), Expect = 0.013
Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
Query: 268 ETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLN 327
E++ ++D++ LI+L + N D + ++ EN ++E E E E + + + S N
Sbjct: 995 ESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGEN------LEEDEEEEEGGAETEEQSGN 1048
Query: 328 KSQLDDCPRDSGCYISSGNSDNGKEDLESEN 358
+S++++ + G S N D+ E+ E EN
Sbjct: 1049 ESEVNEPEEEEG----SDNDDDEGEEEEEEN 1075
>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
sapiens]
Length = 506
Score = 37.7 bits (86), Expect = 0.017
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 182 DSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVD 220
D L ++KGDI+ I K G W G LN K G+F YV+
Sbjct: 455 DELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVE 493
>gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo
sapiens]
Length = 428
Score = 37.7 bits (86), Expect = 0.017
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 182 DSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVD 220
D L ++KGDI+ I K G W G LN K G+F YV+
Sbjct: 377 DELNLEKGDIVIIHEKKEEGWWFGSLNGKKGHFPAAYVE 415
>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 170 VHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAP 229
V F + D L KGD+I + G W G LN + G F YV
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---------- 60
Query: 230 KKIKANRRSNSKKSKTLQ 247
+++KA+ + S KS TL+
Sbjct: 61 REVKASEKPVSPKSGTLK 78
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 170 VHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAP 229
V F + D L KGD+I + G W G LN + G F YV
Sbjct: 139 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---------- 188
Query: 230 KKIKANRRSNSKKSKTLQ 247
+++KA+ + S KS TL+
Sbjct: 189 REVKASEKPVSPKSGTLK 206
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 170 VHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAP 229
V F + D L KGD+I + G W G LN + G F YV
Sbjct: 189 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---------- 238
Query: 230 KKIKANRRSNSKKSKTLQ 247
+++KA+ + S KS TL+
Sbjct: 239 REVKASEKPVSPKSGTLK 256
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 170 VHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAP 229
V F + D L KGD+I + G W G LN + G F YV
Sbjct: 168 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---------- 217
Query: 230 KKIKANRRSNSKKSKTLQ 247
+++KA+ + S KS TL+
Sbjct: 218 REVKASEKPVSPKSGTLK 235
>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 37.4 bits (85), Expect = 0.022
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 170 VHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAP 229
V F + D L KGD+I + G W G LN + G F YV
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV---------- 60
Query: 230 KKIKANRRSNSKKSKTLQ 247
+++KA+ + S KS TL+
Sbjct: 61 REVKASEKPVSPKSGTLK 78
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 37.4 bits (85), Expect = 0.022
Identities = 34/135 (25%), Positives = 49/135 (36%), Gaps = 5/135 (3%)
Query: 32 NNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTMKKKVGKKYIKALSE 91
++S S S+ + G T G E K N GG G R S + + S
Sbjct: 2563 SSSGSSSSSSSSSSSGSETEGEEEGDK--NGDGGCGTGGRNCSAASSRAASPASSSSSSS 2620
Query: 92 EKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSLYSGQSSSSGITSCSDGTSNRDS 151
++ +S + + S +S S S S SSSS +S S T++ DS
Sbjct: 2621 SSSSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677
Query: 152 FRLDDDGPYSGPFCG 166
DD P G
Sbjct: 2678 SCSSDDEAAPAPTAG 2692
>gi|153791893 zinc finger, BED-type containing 4 [Homo sapiens]
Length = 1171
Score = 37.4 bits (85), Expect = 0.022
Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%)
Query: 228 APKKIKANRRSNSKKSKTLQEFLERIHLQEYTSTLLLN---GYETLEDLKDIKESHLIEL 284
A K +A R S + TL + + +H+ +L G +T+ L+ +KE+ + L
Sbjct: 936 ALKPFEAASREMSTQMSTLSQVIPMVHILNRKVEMLFEETMGIDTM--LRSLKEAMVSRL 993
Query: 285 NIENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISS 344
+ D R + + + + E+E E L ++ L S +D C S
Sbjct: 994 SATLHDPRYVFATLLDPRYKASLFTEEEAEQYKQDLIRELELMNSTSEDVAASHRCDAGS 1053
Query: 345 GNSDNGKEDLESENLSDMVHKIIITEPSD 373
+ D+ E ENL +V K+ +P +
Sbjct: 1054 PSKDSAAE----ENLWSLVAKVKKKDPRE 1078
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,464,408
Number of Sequences: 37866
Number of extensions: 756141
Number of successful extensions: 2975
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 2751
Number of HSP's gapped (non-prelim): 272
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.