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Search of human proteins with 48375173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48375173 microtubule-associated protein 6 isoform 1 [Homo
sapiens]
(813 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48375173 microtubule-associated protein 6 isoform 1 [Homo sap... 1652 0.0
gi|48375167 microtubule-associated protein 6 isoform 2 [Homo sap... 896 0.0
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 90 1e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 90 1e-17
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 89 1e-17
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 88 3e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 88 3e-17
gi|163965366 nascent polypeptide-associated complex alpha subuni... 85 3e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 81 4e-15
gi|150170670 piccolo isoform 2 [Homo sapiens] 79 2e-14
gi|150378539 piccolo isoform 1 [Homo sapiens] 79 2e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 78 4e-14
gi|13376306 MAP6 domain containing 1 [Homo sapiens] 77 8e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 76 1e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 74 7e-13
gi|110349719 titin isoform N2-A [Homo sapiens] 73 9e-13
gi|160707881 formin 2 [Homo sapiens] 68 4e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 65 3e-10
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 64 7e-10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 62 2e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 62 2e-09
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 62 2e-09
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 62 2e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 2e-09
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 62 2e-09
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 62 2e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 6e-09
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens] 60 8e-09
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens] 60 8e-09
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens] 60 8e-09
>gi|48375173 microtubule-associated protein 6 isoform 1 [Homo
sapiens]
Length = 813
Score = 1652 bits (4278), Expect = 0.0
Identities = 813/813 (100%), Positives = 813/813 (100%)
Query: 1 MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP 60
MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP
Sbjct: 1 MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP 60
Query: 61 SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV 120
SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV
Sbjct: 61 SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV 120
Query: 121 MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI 180
MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI
Sbjct: 121 MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI 180
Query: 181 SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR 240
SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR
Sbjct: 181 SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR 240
Query: 241 KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS 300
KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS
Sbjct: 241 KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS 300
Query: 301 YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI 360
YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI
Sbjct: 301 YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI 360
Query: 361 RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK 420
RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK
Sbjct: 361 RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK 420
Query: 421 PDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQE 480
PDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQE
Sbjct: 421 PDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQE 480
Query: 481 PLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQ 540
PLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQ
Sbjct: 481 PLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQ 540
Query: 541 SPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVS 600
SPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVS
Sbjct: 541 SPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVS 600
Query: 601 APVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKN 660
APVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKN
Sbjct: 601 APVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKN 660
Query: 661 QGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPIL 720
QGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPIL
Sbjct: 661 QGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPIL 720
Query: 721 PVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLK 780
PVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLK
Sbjct: 721 PVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLK 780
Query: 781 TQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
TQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP
Sbjct: 781 TQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
>gi|48375167 microtubule-associated protein 6 isoform 2 [Homo
sapiens]
Length = 439
Score = 896 bits (2316), Expect = 0.0
Identities = 439/439 (100%), Positives = 439/439 (100%)
Query: 1 MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP 60
MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP
Sbjct: 1 MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPP 60
Query: 61 SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV 120
SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV
Sbjct: 61 SARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSV 120
Query: 121 MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI 180
MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI
Sbjct: 121 MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQI 180
Query: 181 SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR 240
SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR
Sbjct: 181 SAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR 240
Query: 241 KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS 300
KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS
Sbjct: 241 KAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSS 300
Query: 301 YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI 360
YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI
Sbjct: 301 YRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRI 360
Query: 361 RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK 420
RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK
Sbjct: 361 RSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK 420
Query: 421 PDDKEQSKEMNNKLAEAKE 439
PDDKEQSKEMNNKLAEAKE
Sbjct: 421 PDDKEQSKEMNNKLAEAKE 439
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 89.7 bits (221), Expect = 1e-17
Identities = 128/549 (23%), Positives = 195/549 (35%), Gaps = 55/549 (10%)
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKP--IKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPT 348
++ S+ +S+ E + +K K K KP KPP + FK T
Sbjct: 140 KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST 199
Query: 349 TADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAA 408
T NKV +I + ++P P + P+ +SK + + + T + K+ +
Sbjct: 200 TQHNKVSTSPKITT--AKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN---- 252
Query: 409 KKKSAEGPSTTKPDDKEQSKEMNNK--LAEAKESLAQPVSDS-SKTQGPVATEPD----- 460
K+ S +G T + QS E + LA + LA+P + + T+GP T P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 312
Query: 461 --KDQGSVVPG-----LLKGQGPMVQEPLKKQGSVVPGPPKDLGPMI---PLPVKDQDHT 510
K+ S P +K +EP P PK+ P P P ++
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE-P 371
Query: 511 VPEPLKNESPVI--SAPV--KDQGPSVPVPPKNQSPMVPAKV--KDQGSVVPE----SLK 560
P K +P SAP K+ P+ P P +P PA K+ P+ + K
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431
Query: 561 DQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPI 620
+ P P+ AP PAP + P + K+ P + P PAP +
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKS-- 488
Query: 621 VPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPV 680
P K+ P + P P+ P + AP + + P K P
Sbjct: 489 APTTTKEPAPTTTKSA----PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 681 KDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQP--PKNQ 738
P+ + AP + P P + K P P + P L P P+
Sbjct: 545 P----TTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 739 GRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVS-PLPR 797
PE L P P P ++P P K P P+ P++P T P P
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 798 VMIPTAPHT 806
TAP T
Sbjct: 659 TPKETAPTT 667
Score = 84.0 bits (206), Expect = 5e-16
Identities = 122/531 (22%), Positives = 176/531 (33%), Gaps = 59/531 (11%)
Query: 298 SSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVID 356
S++ N+ I KPI +P PP+ ETS + + +K TT NK
Sbjct: 198 STTQHNKVSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTS 256
Query: 357 RRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGP 416
S KE +EK S + P + KPT KA+ G A P
Sbjct: 257 TDGKEKTTSA--KETQSIEKTSAKDLAPTSKVLA-KPTPKAET--TTKGPALTTPKEPTP 311
Query: 417 STTKPDDKEQSKEMN-NKLAEAKESLAQPVSDSSKTQGPVATEP----DKDQGSVVPGLL 471
+T K KE + A + +P ++K+ EP K+ P
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--- 368
Query: 472 KGQGPMV-QEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG 530
K P +EP P PK+ P P P P + P + P K+
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 427
Query: 531 PS----VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
P+ P PK +P P K P+ P+ P P + P P K+ P
Sbjct: 428 PTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAP 483
Query: 587 MVSAS----VKDQGPMV--SAPV--KDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKD 638
+ S K+ P SAP K+ P P PAP + P + P K+
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 542
Query: 639 QDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAV 698
P P+ P + AP + + P K+ P+
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTP------------KETAPTTPKKLTPTTPEK 590
Query: 699 VAPV--KNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVP 756
+AP + P PE + P P + P P EP P P P
Sbjct: 591 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAP 649
Query: 757 LKDQDPLVPVPAKDQGPAVPE-----PLKTQGPRDPQLPTVSPLPRVMIPT 802
++P P K+ P P+ LK P P+ P P+ + PT
Sbjct: 650 TTPKEP-APTTPKETAPTTPKGTAPTTLKEPAPTTPK----KPAPKELAPT 695
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/608 (21%), Positives = 187/608 (30%), Gaps = 70/608 (11%)
Query: 60 PSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTS--GPA 117
P+++ +A T A+ A T P PT +EPA+ + + S T+ PA
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 118 DSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP 177
+ + K P + P AP + ++ P + P PK
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 178 VQISAASQASAPILGAPKRRPQSQERWPVQAAAE---AREQEAAPGGAGGLAAGKASGAD 234
A + P PK + + P E +E AP A A
Sbjct: 402 ---PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEP 457
Query: 235 ERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVA 294
T ++ P + E P A P ++A
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA---------PTTP 508
Query: 295 SAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKV 354
S + E T +P KP P + A + PTT
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 564
Query: 355 IDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAE 414
EP PK P+ T PT K + A + E
Sbjct: 565 ----------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPE 613
Query: 415 GPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVA-TEP-DKDQGSVVPGLLK 472
P+ T P++ + A A + +P + K P EP P K
Sbjct: 614 EPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 669
Query: 473 GQGPMVQEPLKKQGSVVP--GPPKDLGPMIPLPVKDQDHTVPEPLKN--ESPVISAPVKD 528
G P LK+ P PK+L P T EP + P + P K
Sbjct: 670 GTAPTT---LKEPAPTTPKKPAPKELAPT----------TTKEPTSTTCDKPAPTTP-KG 715
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P+ P P +P PA +G+ P +LK+ P P K AP AP +GP
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGT-APTTLKEPAPTTP---KKPAPKELAPTTTKGPTS 771
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGP-----MVSAPIKDQDPMV 643
+ S K P + P K+ P P P PAP E P VS P ++P
Sbjct: 772 TTSDK---PAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 827
Query: 644 PEHPKDES 651
DES
Sbjct: 828 IHKSPDES 835
Score = 43.5 bits (101), Expect = 8e-04
Identities = 94/476 (19%), Positives = 140/476 (29%), Gaps = 67/476 (14%)
Query: 371 PPKVEK---PSVQSSKPKKTSA-SHKPTRKAKDKQAVSGQAAKKKSA--EGPSTTKPDDK 424
PP +K PS S K T+ S KP K K K+ + + ++ + E ++
Sbjct: 72 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 425 EQSKEMNNKLAEAKESLAQ-------PVSDSSKTQGPVATEP-----DKDQGSVVPGLLK 472
S K+ +K S A V D+ K + P D+ + G K
Sbjct: 132 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191
Query: 473 GQGPMVQEPLKKQGSVVP----GPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKD 528
P + S P P + P +P P D + E+ V +
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTT 250
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
K ++ K+ S+ S KD P K P
Sbjct: 251 TNKQTSTDGKEKT----TSAKETQSIEKTSAKDLAPTSKVLAK--------------PTP 292
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPK 648
A +GP ++ P K+ P P P P P + SAP ++P P
Sbjct: 293 KAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTT----IKSAPTTPKEPA----PT 343
Query: 649 DESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
+ T P + + EP P + E A + K P
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 709 VPESVKNQDPI----------LPVLVKDQGPTVLQP-PKNQGRIVPEPLKNQVPIVPVPL 757
P+ P P K+ PT +P P P K P P
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 457
Query: 758 KDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
P P P + P+ P + PT + P + T E SP
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513
Score = 37.4 bits (85), Expect = 0.056
Identities = 116/547 (21%), Positives = 166/547 (30%), Gaps = 106/547 (19%)
Query: 38 EHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAA 97
+ P + P P +PA P A +PA A T P PT +EPA
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483
Query: 98 GPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQ 157
+S P +T PA + + K EPS E P+ T +
Sbjct: 484 TTTKSAP------TTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPK 533
Query: 158 KDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEA 217
K P P P P + A + P PK A +E
Sbjct: 534 K-----PAPTTPKEP-APTTPKEPAPTTTKKPAPTTPKE------------PAPTTPKET 575
Query: 218 APGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
AP T +K P + A + P P ++ T PE
Sbjct: 576 AP-----------------TTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPE--- 613
Query: 278 GRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYS 337
+ E + ++ N + P +P P K P ET+ +
Sbjct: 614 -----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAPTTPKETAPT 666
Query: 338 AQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKA 397
KG A PTT EP PK KP+ + P T +PT
Sbjct: 667 TP-KGTA--PTT--------------LKEPAPTTPK--KPAPKELAPTTTK---EPTSTT 704
Query: 398 KDKQAVS---GQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGP 454
DK A + G A P+T K K A +L +P + K P
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK------GTAPTTLKEPAPTTPKKPAP 758
Query: 455 VATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEP 514
P +G P P P K+ P P P P P T PE
Sbjct: 759 KELAPTTTKG---PTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAP------TTPET 808
Query: 515 LKNESPVISAPVKDQGP-SVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQ 573
+ +S P + P ++ P +P + A+ P++L + P+ P +
Sbjct: 809 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL-ENSPKEPGVPTTK 861
Query: 574 APMVPAP 580
P P
Sbjct: 862 TPAATKP 868
Score = 31.2 bits (69), Expect = 4.0
Identities = 76/450 (16%), Positives = 124/450 (27%), Gaps = 36/450 (8%)
Query: 31 TKYSEATEHPGAP--PQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG 88
TK T AP P+ P P +PA P A +PA A T P
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 89 PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDA 148
PT ++PA + P P + + PE E
Sbjct: 553 PTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611
Query: 149 PFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQA 208
P E P P + P P + +A + P PK + + P
Sbjct: 612 PEE------------PTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 209 AAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP------LP 262
+ G A A ++ ++ P + P P
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 263 AAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQ 322
+ T P+ ++E + E T P KP
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 323 YKPPDDKMVHETSYSAQFKGEASKPTTAD---------NKVIDRRRIRSLYSEPFKEPPK 373
P + A + PTT + + + +++ P + P+
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 374 VE---KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
+ P + PK+ T A + + AK K+ E T P+ + +M
Sbjct: 839 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT--TAKDKTTERDLRTTPETTTAAPKM 896
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPD 460
+ A E + ++ TQ T D
Sbjct: 897 TKETATTTEKTTESKITATTTQVTSTTTQD 926
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 89.7 bits (221), Expect = 1e-17
Identities = 128/549 (23%), Positives = 195/549 (35%), Gaps = 55/549 (10%)
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKP--IKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPT 348
++ S+ +S+ E + +K K K KP KPP + FK T
Sbjct: 181 KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST 240
Query: 349 TADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAA 408
T NKV +I + ++P P + P+ +SK + + + T + K+ +
Sbjct: 241 TQHNKVSTSPKITT--AKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN---- 293
Query: 409 KKKSAEGPSTTKPDDKEQSKEMNNK--LAEAKESLAQPVSDS-SKTQGPVATEPD----- 460
K+ S +G T + QS E + LA + LA+P + + T+GP T P
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 353
Query: 461 --KDQGSVVPG-----LLKGQGPMVQEPLKKQGSVVPGPPKDLGPMI---PLPVKDQDHT 510
K+ S P +K +EP P PK+ P P P ++
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE-P 412
Query: 511 VPEPLKNESPVI--SAPV--KDQGPSVPVPPKNQSPMVPAKV--KDQGSVVPE----SLK 560
P K +P SAP K+ P+ P P +P PA K+ P+ + K
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472
Query: 561 DQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPI 620
+ P P+ AP PAP + P + K+ P + P PAP +
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEP-APTTPKEPAPTTTKEPSPTTPKEPAPTTTKS-- 529
Query: 621 VPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPV 680
P K+ P + P P+ P + AP + + P K P
Sbjct: 530 APTTTKEPAPTTTKSA----PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 681 KDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQP--PKNQ 738
P+ + AP + P P + K P P + P L P P+
Sbjct: 586 P----TTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 739 GRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVS-PLPR 797
PE L P P P ++P P K P P+ P++P T P P
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 798 VMIPTAPHT 806
TAP T
Sbjct: 700 TPKETAPTT 708
Score = 84.0 bits (206), Expect = 5e-16
Identities = 122/531 (22%), Positives = 176/531 (33%), Gaps = 59/531 (11%)
Query: 298 SSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVID 356
S++ N+ I KPI +P PP+ ETS + + +K TT NK
Sbjct: 239 STTQHNKVSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTS 297
Query: 357 RRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGP 416
S KE +EK S + P + KPT KA+ G A P
Sbjct: 298 TDGKEKTTSA--KETQSIEKTSAKDLAPTSKVLA-KPTPKAET--TTKGPALTTPKEPTP 352
Query: 417 STTKPDDKEQSKEMN-NKLAEAKESLAQPVSDSSKTQGPVATEP----DKDQGSVVPGLL 471
+T K KE + A + +P ++K+ EP K+ P
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--- 409
Query: 472 KGQGPMV-QEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG 530
K P +EP P PK+ P P P P + P + P K+
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 468
Query: 531 PS----VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
P+ P PK +P P K P+ P+ P P + P P K+ P
Sbjct: 469 PTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAP 524
Query: 587 MVSAS----VKDQGPMV--SAPV--KDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKD 638
+ S K+ P SAP K+ P P PAP + P + P K+
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 583
Query: 639 QDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAV 698
P P+ P + AP + + P K+ P+
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTP------------KETAPTTPKKLTPTTPEK 631
Query: 699 VAPV--KNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVP 756
+AP + P PE + P P + P P EP P P P
Sbjct: 632 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAP 690
Query: 757 LKDQDPLVPVPAKDQGPAVPE-----PLKTQGPRDPQLPTVSPLPRVMIPT 802
++P P K+ P P+ LK P P+ P P+ + PT
Sbjct: 691 TTPKEP-APTTPKETAPTTPKGTAPTTLKEPAPTTPK----KPAPKELAPT 736
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/608 (21%), Positives = 187/608 (30%), Gaps = 70/608 (11%)
Query: 60 PSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTS--GPA 117
P+++ +A T A+ A T P PT +EPA+ + + S T+ PA
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 118 DSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP 177
+ + K P + P AP + ++ P + P PK
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 178 VQISAASQASAPILGAPKRRPQSQERWPVQAAAE---AREQEAAPGGAGGLAAGKASGAD 234
A + P PK + + P E +E AP A A
Sbjct: 443 ---PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEP 498
Query: 235 ERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVA 294
T ++ P + E P A P ++A
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA---------PTTP 549
Query: 295 SAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKV 354
S + E T +P KP P + A + PTT
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 605
Query: 355 IDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAE 414
EP PK P+ T PT K + A + E
Sbjct: 606 ----------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPE 654
Query: 415 GPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVA-TEP-DKDQGSVVPGLLK 472
P+ T P++ + A A + +P + K P EP P K
Sbjct: 655 EPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 710
Query: 473 GQGPMVQEPLKKQGSVVP--GPPKDLGPMIPLPVKDQDHTVPEPLKN--ESPVISAPVKD 528
G P LK+ P PK+L P T EP + P + P K
Sbjct: 711 GTAPTT---LKEPAPTTPKKPAPKELAPT----------TTKEPTSTTCDKPAPTTP-KG 756
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P+ P P +P PA +G+ P +LK+ P P K AP AP +GP
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGT-APTTLKEPAPTTP---KKPAPKELAPTTTKGPTS 812
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGP-----MVSAPIKDQDPMV 643
+ S K P + P K+ P P P PAP E P VS P ++P
Sbjct: 813 TTSDK---PAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 868
Query: 644 PEHPKDES 651
DES
Sbjct: 869 IHKSPDES 876
Score = 43.5 bits (101), Expect = 8e-04
Identities = 94/476 (19%), Positives = 140/476 (29%), Gaps = 67/476 (14%)
Query: 371 PPKVEK---PSVQSSKPKKTSA-SHKPTRKAKDKQAVSGQAAKKKSA--EGPSTTKPDDK 424
PP +K PS S K T+ S KP K K K+ + + ++ + E ++
Sbjct: 113 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 425 EQSKEMNNKLAEAKESLAQ-------PVSDSSKTQGPVATEP-----DKDQGSVVPGLLK 472
S K+ +K S A V D+ K + P D+ + G K
Sbjct: 173 SSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232
Query: 473 GQGPMVQEPLKKQGSVVP----GPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKD 528
P + S P P + P +P P D + E+ V +
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTT 291
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
K ++ K+ S+ S KD P K P
Sbjct: 292 TNKQTSTDGKEKT----TSAKETQSIEKTSAKDLAPTSKVLAK--------------PTP 333
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPK 648
A +GP ++ P K+ P P P P P + SAP ++P P
Sbjct: 334 KAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTT----IKSAPTTPKEPA----PT 384
Query: 649 DESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
+ T P + + EP P + E A + K P
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 709 VPESVKNQDPI----------LPVLVKDQGPTVLQP-PKNQGRIVPEPLKNQVPIVPVPL 757
P+ P P K+ PT +P P P K P P
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 498
Query: 758 KDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
P P P + P+ P + PT + P + T E SP
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554
Score = 37.4 bits (85), Expect = 0.056
Identities = 116/547 (21%), Positives = 166/547 (30%), Gaps = 106/547 (19%)
Query: 38 EHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAA 97
+ P + P P +PA P A +PA A T P PT +EPA
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524
Query: 98 GPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQ 157
+S P +T PA + + K EPS E P+ T +
Sbjct: 525 TTTKSAP------TTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPK 574
Query: 158 KDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEA 217
K P P P P + A + P PK A +E
Sbjct: 575 K-----PAPTTPKEP-APTTPKEPAPTTTKKPAPTTPKE------------PAPTTPKET 616
Query: 218 APGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
AP T +K P + A + P P ++ T PE
Sbjct: 617 AP-----------------TTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPE--- 654
Query: 278 GRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYS 337
+ E + ++ N + P +P P K P ET+ +
Sbjct: 655 -----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAPTTPKETAPT 707
Query: 338 AQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKA 397
KG A PTT EP PK KP+ + P T +PT
Sbjct: 708 TP-KGTA--PTT--------------LKEPAPTTPK--KPAPKELAPTTTK---EPTSTT 745
Query: 398 KDKQAVS---GQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGP 454
DK A + G A P+T K K A +L +P + K P
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK------GTAPTTLKEPAPTTPKKPAP 799
Query: 455 VATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEP 514
P +G P P P K+ P P P P P T PE
Sbjct: 800 KELAPTTTKG---PTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAP------TTPET 849
Query: 515 LKNESPVISAPVKDQGP-SVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQ 573
+ +S P + P ++ P +P + A+ P++L + P+ P +
Sbjct: 850 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL-ENSPKEPGVPTTK 902
Query: 574 APMVPAP 580
P P
Sbjct: 903 TPAATKP 909
Score = 31.2 bits (69), Expect = 4.0
Identities = 76/450 (16%), Positives = 124/450 (27%), Gaps = 36/450 (8%)
Query: 31 TKYSEATEHPGAP--PQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG 88
TK T AP P+ P P +PA P A +PA A T P
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 89 PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDA 148
PT ++PA + P P + + PE E
Sbjct: 594 PTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652
Query: 149 PFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQA 208
P E P P + P P + +A + P PK + + P
Sbjct: 653 PEE------------PTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 209 AAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP------LP 262
+ G A A ++ ++ P + P P
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 263 AAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQ 322
+ T P+ ++E + E T P KP
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 323 YKPPDDKMVHETSYSAQFKGEASKPTTAD---------NKVIDRRRIRSLYSEPFKEPPK 373
P + A + PTT + + + +++ P + P+
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 374 VE---KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
+ P + PK+ T A + + AK K+ E T P+ + +M
Sbjct: 880 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT--TAKDKTTERDLRTTPETTTAAPKM 937
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPD 460
+ A E + ++ TQ T D
Sbjct: 938 TKETATTTEKTTESKITATTTQVTSTTTQD 967
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 89.4 bits (220), Expect = 1e-17
Identities = 118/391 (30%), Positives = 165/391 (42%), Gaps = 55/391 (14%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLP 503
PV+ + PV T PD G VVP + GP V G VVP P D P IP+
Sbjct: 469 PVTSADIPLVPV-TPPD---GPVVP-VTSADGP-VAPVSSADGPVVPVTPAD-SPFIPVT 521
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
D D VP +SPV+S + P++PV P + SP+VP + G VVP + D
Sbjct: 522 TAD-DLIVPVT-PADSPVLSV-TPAESPAIPVTPAD-SPIVPVTPAN-GPVVPVTSADS- 575
Query: 564 PRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPA 623
P +P + P+VP D P+V + D P++S + D P VP + P+VP
Sbjct: 576 PFVPV-IPADGPVVPVTPADS-PVVPVTPADS-PVLSVTLADS-PAVPV-TPADSPVVPV 630
Query: 624 PVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSE------PVKNQGLVVS 677
D GP+V D P VP P D+ ++ P ++ V++ PV + V
Sbjct: 631 TPAD-GPVVPVASADS-PFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVI 688
Query: 678 GPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKN 737
+VP A V P G V + P++PV D + PP
Sbjct: 689 PVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSA---DGPVVPVTSADSPFVPVTPP-- 743
Query: 738 QGRIVP--------EPLKN-QVPIVPV--------PLKDQD-PLVPV-PAKDQGPAVP-- 776
G +VP P+ + P+VPV P+ D P+VPV PA GPAVP
Sbjct: 744 DGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVT 803
Query: 777 ---EPLKTQGPRDPQLPTVSPLPRVMIPTAP 804
P P D + V+P ++P P
Sbjct: 804 SADSPFVPVIPADSPVVPVTPADDPIVPVTP 834
Score = 82.8 bits (203), Expect = 1e-15
Identities = 115/387 (29%), Positives = 153/387 (39%), Gaps = 60/387 (15%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGS-VVPGPPKDLGPMIPL 502
PV + + PV D VVP + GP+V P+ S VVP P D P+IP
Sbjct: 2383 PVVSVTTSDSPVIPVTPTDS-PVVP-VAPADGPVV--PVTSVDSPVVPVTPAD-SPVIP- 2436
Query: 503 PVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKN---------QSPMVPAKVKDQGS 553
V D V + PV+S D GP VPV + SP+VP D G
Sbjct: 2437 -VTPADSLVVPATPADDPVVSVTPAD-GPVVPVTTADIPVISVTSADSPVVPVTPAD-GL 2493
Query: 554 VVPESLKDQGPRIPEPVKNQAPMVPAPVKD---------EGPMVSASVKDQGPMVSAPVK 604
VVP + D P P+VP D + P+VS + D P+
Sbjct: 2494 VVPVTSADSVVVPATPA--DCPLVPVDPADSPIVLFTPYDNPVVSVT-SDDSPVFPVTPA 2550
Query: 605 DQG--PIVPAPVK------GEGPIVPAPVKDEGPMVSAPIKDQD-PMVPEHPKDESAMAT 655
D P+ PA V G+GP+VP D + P+ D P+ P P D
Sbjct: 2551 DSSVVPVTPAGVPVVPVTPGDGPVVPVTPADS---LVVPVTSADSPVFPVTPADSPVF-- 2605
Query: 656 APIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKN 715
P+ +V VV D VV+ A D VV GPVVP + +
Sbjct: 2606 -PVSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPA---DGPVVPVTPANGPVVPVTSAD 2661
Query: 716 QD--PILP---VLVKDQGPTVLQPP--KNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPA 768
P++P ++V D VL P G +VP+ + P+VPV D DP+VPV
Sbjct: 2662 SPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADD--PVVPVTPGD-DPVVPVTP 2718
Query: 769 KDQGPAVPEPLKTQGPRDPQLPTVSPL 795
D P +P GP P P V P+
Sbjct: 2719 GDD-PVIPVTPADDGPFVPVTPAVGPV 2744
Score = 80.9 bits (198), Expect = 4e-15
Identities = 128/437 (29%), Positives = 168/437 (38%), Gaps = 100/437 (22%)
Query: 444 PVSDSSKTQGPVA--TEPDKDQGSVVPG-----LLKGQGPMVQEPLKKQGSVVPGPPKDL 496
PV + GPV T D V+P L +V G +VP DL
Sbjct: 2643 PVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVP----DL 2698
Query: 497 GPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVP 556
+PV D V + PVI D GP VPV P P+VP D SVVP
Sbjct: 2699 ADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPFVPVTPA-VGPVVPDLTADD-SVVP 2756
Query: 557 ESLKDQGPRIPEPVKNQAP----MVPAPVKDE-----------GPMVSASVKDQGPMVSA 601
+SL D +PV + P +VP V+D GP+V+ S D P+VS
Sbjct: 2757 DSLTD------DPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAAD-CPVVSV 2809
Query: 602 PVKDQGPIVPAPVK---------GEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESA 652
P+ D G +V P G +VP PV D GP+ S P D P+VP D
Sbjct: 2810 PLTD-GLVVLCPPDEVPAVHDSVTNGLVVPDPVID-GPVFSNPSVD-GPIVPVASADNPG 2866
Query: 653 MATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPES 712
+ PI+ +V +P +V S P DV+V D A V GPVVP+
Sbjct: 2867 VPD-PIR-AFPVVPKPSTFSPVVTSTPADWIDVIVTP----ADCADVPVNPVNGPVVPD- 2919
Query: 713 VKNQDPILPVLVKDQ----GP-----TVLQPPKNQGRIVPEPLKN--QVP-------IVP 754
+ P++PV D P V+ P G +V +P + VP + P
Sbjct: 2920 LSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAP 2979
Query: 755 VPLKDQ------------------DPLVPVPAKD---------QGPAVPEPLKTQGPRDP 787
V L + P+VP P+ D G VP PL GP P
Sbjct: 2980 VTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPNPL-LAGPVVP 3038
Query: 788 QLPTVSPLPRVMIPTAP 804
PT PL V++ P
Sbjct: 3039 VTPTDGPLAPVILADCP 3055
Score = 79.0 bits (193), Expect = 2e-14
Identities = 125/410 (30%), Positives = 171/410 (41%), Gaps = 73/410 (17%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-SVVPGPPKDLGPMIPL 502
PV + PV D +VVP L GP+V P+ VVP P + GP+ P+
Sbjct: 1584 PVVSVTIADSPVIPVTPADS-TVVPVTL-ADGPVV--PVTSVDIPVVPVTPAN-GPVAPV 1638
Query: 503 -PVKDQDHTVPEPLKNESPVISA--PVKDQGPS----VPVPPKNQSPMVPAKVKDQGSVV 555
PV D +V + PV SA PV P+ VPV P + SP+VP D V+
Sbjct: 1639 TPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPAD-SPIVPVTPADSPVVL 1697
Query: 556 PESLKDQGPRIPEPVKNQAPMVPAPVKD-----------EGPMVSASVKDQGPMVSAPVK 604
S P IP + +P+VP D +GP+V + D P+ P
Sbjct: 1698 VTSA--DSPVIPVTPAD-SPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPA- 1753
Query: 605 DQGPIVP--------APV-KGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMAT 655
GP+VP APV +GP+VP D P+V D DP VP P D +
Sbjct: 1754 -DGPVVPVTSADGPVAPVSSADGPVVPVTPAD-SPVVPVTTAD-DPTVPVTPADSPVVPV 1810
Query: 656 -------APIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
P+ + S + GLVV D +VVP ++ P PV
Sbjct: 1811 PPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDV-LVVPVSP---TDGILVPDLADDPV 1866
Query: 709 VPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKD--------- 759
V ++ + P++PV D P VL P + G +VP + P+VPV D
Sbjct: 1867 VSVTIAD-SPVIPVTPAD-SPVVLVTPAD-GPVVPVTSVDN-PVVPVTPADNPVIPVTPV 1922
Query: 760 QDPLVPV-PAKDQGPAVP-----EPLKTQGPRDPQLPTVSPLPRVMIPTA 803
DP+VPV PA D P VP P+ + P D + V+P +IP A
Sbjct: 1923 DDPVVPVTPADD--PIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVA 1970
Score = 73.6 bits (179), Expect = 7e-13
Identities = 115/403 (28%), Positives = 163/403 (40%), Gaps = 106/403 (26%)
Query: 475 GPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKD---------QDHTVPEPLKNESPVISAP 525
GP+V + L G VV P P++P+ + D VP+P ++ PV++
Sbjct: 3173 GPVVPD-LTTDGLVVSVTPAG-APVVPVFLTDCPDVTVTPADSPVVPDP-SSDGPVVADS 3229
Query: 526 VKDQGPSVPVPPKNQS--PMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKD 583
+ D G VPV P + S P PA G VVP+ D GP P+P + P+VP D
Sbjct: 3230 LDDDG-LVPVTPADDSVVPDSPAN----GLVVPDPTTD-GPVAPDPSVD-GPVVPVTPAD 3282
Query: 584 EGPMVSASVKD-----------------------------QGPMVSAPVKDQGPIVPAPV 614
P VS ++ D P+++A D + P
Sbjct: 3283 -APTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVTPA 3341
Query: 615 KGEG-PIVPA-----PVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEP 668
E P+ PA PV E P+VS D +VP P D+ + P K +V +P
Sbjct: 3342 DFEDVPVTPANCPDVPVNPESPVVSDLAVDF-LVVPVVPSDDLVVLEPPDKVP--VVPDP 3398
Query: 669 VKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVP---------------ESV 713
+ N GLVVS P+ + D +VV GPV P +SV
Sbjct: 3399 ISN-GLVVSDPITNNTAATDPSV---DGSVVPVSPADGPVAPVTLADCPDVTITPADDSV 3454
Query: 714 KNQDPI------LPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVP 767
+ I +PV + D P V PK+ G +V + L P+VP+P D D + P P
Sbjct: 3455 VSDSKIRAEFEDVPVTIADC-PNVPVNPKS-GPVVSD-LAVDCPVVPIPPPD-DLVAPEP 3510
Query: 768 AKDQGPAVPEPL---------KTQGP--RDPQL-----PTVSP 794
D+ P VP+P+ T GP DP + P VSP
Sbjct: 3511 P-DEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSP 3552
Score = 69.7 bits (169), Expect = 1e-11
Identities = 89/317 (28%), Positives = 136/317 (42%), Gaps = 36/317 (11%)
Query: 475 GPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVP 534
GP+V + L VVP PP D ++ D+ VP+P+ +S V+S P+ D GP V
Sbjct: 3484 GPVVSD-LAVDCPVVPIPPPD--DLVAPEPPDEVPVVPDPI-TDSLVVSDPMTD-GP-VA 3537
Query: 535 VPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKD 594
P +VP V G +V +S+ D I P+ P + D G +V S D
Sbjct: 3538 SDPSIDGIVVPV-VSPSGLLVLDSVADVS--ILPDTSADVPVTPVTLAD-GSVVPDSAPD 3593
Query: 595 QGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMA 654
P+V PV V + +G +VP P D GP+V P D + + P
Sbjct: 3594 C-PVV--PVLPTDGFVVLDLLVDGVVVPNPA-DVGPVVPDPTTDGPDSIKDFPLVPDPWP 3649
Query: 655 TAPI----KNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVP 710
P+ + G +V + + +V P D +V D+ VV + GPVVP
Sbjct: 3650 DCPVVPVTRTDGPVVLDSSADGVVVPVTPGDDSVALVTPT----DNLVVPDLTTDGPVVP 3705
Query: 711 ESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAK- 769
+ + +L L D ++ P + +VP + + P+ P+ D PLVP P+
Sbjct: 3706 DPSADGPVVLVSLADD---LLVPNPPVKDTVVPNSVADN-PVALDPVTDC-PLVPEPSAN 3760
Query: 770 --------DQGPAVPEP 778
D+GP VP+P
Sbjct: 3761 GLVVTDSLDEGPVVPDP 3777
Score = 69.3 bits (168), Expect = 1e-11
Identities = 112/411 (27%), Positives = 158/411 (38%), Gaps = 99/411 (24%)
Query: 453 GPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKD-QDHTV 511
GPV +P D SVV G +V PL G VVP P D GP+ P+ + D D TV
Sbjct: 3004 GPVVPDPSADS-SVVSNPTT-DGLIVPNPLLA-GPVVPVTPTD-GPLAPVILADCPDVTV 3059
Query: 512 ------------------PEPLKNESPVISAPVKDQ----GPS----VPVPPKNQS--PM 543
P+P E V+S P D PS V P + + P+
Sbjct: 3060 TPADGPVVCAFTTGGPVFPDPTA-EGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPV 3118
Query: 544 VPAKVKD------QGSVVPESLKD---------QGPRIPEPVKNQAPMVPAPVKDEGPMV 588
+PA D SVVP+ D P+P ++ P+V P+ D GP+V
Sbjct: 3119 IPADCPDVLVNLVNDSVVPDFTADWTVVSVSPPDDLVAPDP-PDEVPVVLVPITD-GPVV 3176
Query: 589 SASVKDQGPMVSAPVKDQGPIVPA---------PVKGEGPIVPAPVKDEGPMVSAPIKDQ 639
D +V + P+VP + P+VP P D GP+V+ + D
Sbjct: 3177 PDLTTDG--LVVSVTPAGAPVVPVFLTDCPDVTVTPADSPVVPDPSSD-GPVVADSL-DD 3232
Query: 640 DPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVV--VPEHAKV---- 693
D +VP P D+S + +P G +V +P + G V P D VV P A
Sbjct: 3233 DGLVPVTPADDSVVPDSPAN--GLVVPDPTTD-GPVAPDPSVDGPVVPVTPADAPTVSVT 3289
Query: 694 -----------HDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQP------PK 736
D VV+ K GPVV + DP++ D + P P
Sbjct: 3290 LADCPDVTVTPPDGLVVSDSKRGGPVVT-GLSTNDPVITATPADFSDVTVTPADFEDVPV 3348
Query: 737 NQGRIVPEPLKNQVPIVP--------VPLKDQDPLVPVPAKDQGPAVPEPL 779
P+ + P+V VP+ D LV + D+ P VP+P+
Sbjct: 3349 TPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPDPI 3399
Score = 62.8 bits (151), Expect = 1e-09
Identities = 77/258 (29%), Positives = 105/258 (40%), Gaps = 58/258 (22%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLP 503
PV+ + G V PD V +L G +V + L G VVP P D+GP++P P
Sbjct: 3575 PVTPVTLADGSVV--PDSAPDCPVVPVLPTDGFVVLD-LLVDGVVVPNPA-DVGPVVPDP 3630
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
D P+ +K + P++ P D P VPV + P+V D G VVP + D
Sbjct: 3631 TTDG----PDSIK-DFPLVPDPWPDC-PVVPVT-RTDGPVVLDSSAD-GVVVPVTPGDDS 3682
Query: 564 PRIPEPVKN--------QAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKD---------- 605
+ P N P+VP P D GP+V S+ D + + PVKD
Sbjct: 3683 VALVTPTDNLVVPDLTTDGPVVPDPSAD-GPVVLVSLADDLLVPNPPVKDTVVPNSVADN 3741
Query: 606 --------QGPIVPAPVKG---------EGPIVPAPVKDEGPMVSAP---------IKDQ 639
P+VP P EGP+VP P D+ P+V P I
Sbjct: 3742 PVALDPVTDCPLVPEPSANGLVVTDSLDEGPVVPDPSADD-PVVLNPETNGLVVPDISAN 3800
Query: 640 DPMVPEHPKDESAMATAP 657
P+VP+ P D S P
Sbjct: 3801 GPVVPDTPTDGSDATVTP 3818
Score = 61.6 bits (148), Expect = 3e-09
Identities = 112/419 (26%), Positives = 155/419 (36%), Gaps = 84/419 (20%)
Query: 439 ESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGP 498
ES A PV+ + PV D VVP + P+V P VVP P D
Sbjct: 2182 ESPAIPVTPADSPVVPVTPADDP----VVP-VTPADSPIVPVP-PASDPVVPVTPADTPG 2235
Query: 499 MIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPES 558
PV D V +SP++ D P VPV P + SP+ P D G V P +
Sbjct: 2236 S---PVASADGPVVPVTSADSPLVPVTPGDS-PVVPVTPAD-SPVFPVTSAD-GPVFPVT 2289
Query: 559 LKDQGPRIPEPVKNQAPMVPAPVKDEG--PMVSASVKDQGPMVSAPVKDQGPIVPAPVKG 616
L D P P + P+ P D P+ A++ P+V P + G +VP G
Sbjct: 2290 LADD-PVFPVTPADD-PIFPVSPADSPVVPVTPANI----PVVPVPPAN-GSVVPVTSAG 2342
Query: 617 EG--PIVPA-----------------------PVKD--EGPMVSAPIKDQDPMVPEHPKD 649
PI+PA PV D + P+VS D P++P P D
Sbjct: 2343 SPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTSDS-PVIPVTPTD 2401
Query: 650 ESAMATAPIKNQGSMVSE------PVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVK 703
+ AP V+ PV V +VVP A D VV+
Sbjct: 2402 SPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVP--ATPADDPVVSVTP 2459
Query: 704 NQGPVVPE--------SVKNQD-PILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVP 754
GPVVP SV + D P++PV D ++ P + +V P+VP
Sbjct: 2460 ADGPVVPVTTADIPVISVTSADSPVVPVTPADG---LVVPVTSADSVVVPATPADCPLVP 2516
Query: 755 VPLKD---------QDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAP 804
V D +P+V V + D P+ P D + V+P ++P P
Sbjct: 2517 VDPADSPIVLFTPYDNPVVSVTSDD------SPVFPVTPADSSVVPVTPAGVPVVPVTP 2569
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 88.2 bits (217), Expect = 3e-17
Identities = 123/521 (23%), Positives = 183/521 (35%), Gaps = 53/521 (10%)
Query: 318 KAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVIDRRRIRSLYSEPFKEPPKVEK 376
K KP KPP + FK TT NKV +I + ++P P +
Sbjct: 75 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLP- 131
Query: 377 PSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK--L 434
P+ +SK + + + T + K+ + K+ S +G T + QS E + L
Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTN----KQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 435 AEAKESLAQPVSDS-SKTQGPVATEPD-------KDQGSVVPG-----LLKGQGPMVQEP 481
A + LA+P + + T+GP T P K+ S P +K +EP
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 482 LKKQGSVVPGPPKDLGPMI---PLPVKDQDHTVPEPLKNESPVI--SAPV--KDQGPSVP 534
P PK+ P P P ++ P K +P SAP K+ P+ P
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 535 VPPKNQSPMVPAKV--KDQGSVVPE----SLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P +P PA K+ P+ + K+ P P+ AP PAP + P
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-A 365
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPK 648
+ K+ P + P PAP + P K+ P + P P+ P
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS--APTTTKEPAPTTTKSA----PTTPKEPS 419
Query: 649 DESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
+ AP + + P K P P+ + AP + P
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEPAPTTTKKPAPTTPKEPA 475
Query: 709 VPESVKNQDPILPVLVKDQGPTVLQP--PKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPV 766
P + K P P + P L P P+ PE L P P P ++P P
Sbjct: 476 -PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 533
Query: 767 PAKDQGPAVPEPLKTQGPRDPQLPTVS-PLPRVMIPTAPHT 806
K P P+ P++P T P P TAP T
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574
Score = 84.0 bits (206), Expect = 5e-16
Identities = 122/531 (22%), Positives = 176/531 (33%), Gaps = 59/531 (11%)
Query: 298 SSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVID 356
S++ N+ I KPI +P PP+ ETS + + +K TT NK
Sbjct: 105 STTQHNKVSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163
Query: 357 RRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGP 416
S KE +EK S + P + KPT KA+ G A P
Sbjct: 164 TDGKEKTTSA--KETQSIEKTSAKDLAPTSKVLA-KPTPKAET--TTKGPALTTPKEPTP 218
Query: 417 STTKPDDKEQSKEMN-NKLAEAKESLAQPVSDSSKTQGPVATEP----DKDQGSVVPGLL 471
+T K KE + A + +P ++K+ EP K+ P
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--- 275
Query: 472 KGQGPMV-QEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG 530
K P +EP P PK+ P P P P + P + P K+
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 334
Query: 531 PS----VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
P+ P PK +P P K P+ P+ P P + P P K+ P
Sbjct: 335 PTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAP 390
Query: 587 MVSAS----VKDQGPMV--SAPV--KDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKD 638
+ S K+ P SAP K+ P P PAP + P + P K+
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 449
Query: 639 QDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAV 698
P P+ P + AP + + P K+ P+
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTP------------KETAPTTPKKLTPTTPEK 497
Query: 699 VAPV--KNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVP 756
+AP + P PE + P P + P P EP P P P
Sbjct: 498 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAP 556
Query: 757 LKDQDPLVPVPAKDQGPAVPE-----PLKTQGPRDPQLPTVSPLPRVMIPT 802
++P P K+ P P+ LK P P+ P P+ + PT
Sbjct: 557 TTPKEP-APTTPKETAPTTPKGTAPTTLKEPAPTTPK----KPAPKELAPT 602
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/608 (21%), Positives = 187/608 (30%), Gaps = 70/608 (11%)
Query: 60 PSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTS--GPA 117
P+++ +A T A+ A T P PT +EPA+ + + S T+ PA
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 118 DSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP 177
+ + K P + P AP + ++ P + P PK
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 178 VQISAASQASAPILGAPKRRPQSQERWPVQAAAE---AREQEAAPGGAGGLAAGKASGAD 234
A + P PK + + P E +E AP A A
Sbjct: 309 ---PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEP 364
Query: 235 ERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVA 294
T ++ P + E P A P ++A
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA---------PTTP 415
Query: 295 SAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKV 354
S + E T +P KP P + A + PTT
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 471
Query: 355 IDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAE 414
EP PK P+ T PT K + A + E
Sbjct: 472 ----------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPE 520
Query: 415 GPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVA-TEP-DKDQGSVVPGLLK 472
P+ T P++ + A A + +P + K P EP P K
Sbjct: 521 EPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576
Query: 473 GQGPMVQEPLKKQGSVVP--GPPKDLGPMIPLPVKDQDHTVPEPLKN--ESPVISAPVKD 528
G P LK+ P PK+L P T EP + P + P K
Sbjct: 577 GTAPTT---LKEPAPTTPKKPAPKELAPT----------TTKEPTSTTCDKPAPTTP-KG 622
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P+ P P +P PA +G+ P +LK+ P P K AP AP +GP
Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGT-APTTLKEPAPTTP---KKPAPKELAPTTTKGPTS 678
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGP-----MVSAPIKDQDPMV 643
+ S K P + P K+ P P P PAP E P VS P ++P
Sbjct: 679 TTSDK---PAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 734
Query: 644 PEHPKDES 651
DES
Sbjct: 735 IHKSPDES 742
Score = 38.1 bits (87), Expect = 0.033
Identities = 49/239 (20%), Positives = 69/239 (28%), Gaps = 26/239 (10%)
Query: 586 PMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPE 645
P A +GP ++ P K+ P P P P P + SAP ++P
Sbjct: 197 PTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTT----IKSAPTTPKEPA--- 248
Query: 646 HPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQ 705
P + T P + + EP P + E A + K
Sbjct: 249 -PTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 706 GPVVPESVKNQDPI----------LPVLVKDQGPTVLQP-PKNQGRIVPEPLKNQVPIVP 754
P P+ P P K+ PT +P P P K P P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 755 VPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
P P P + P+ P + PT + P + T E SP
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420
Score = 37.4 bits (85), Expect = 0.056
Identities = 116/547 (21%), Positives = 166/547 (30%), Gaps = 106/547 (19%)
Query: 38 EHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAA 97
+ P + P P +PA P A +PA A T P PT +EPA
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390
Query: 98 GPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQ 157
+S P +T PA + + K EPS E P+ T +
Sbjct: 391 TTTKSAP------TTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 158 KDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEA 217
K P P P P + A + P PK A +E
Sbjct: 441 K-----PAPTTPKEP-APTTPKEPAPTTTKKPAPTTPKE------------PAPTTPKET 482
Query: 218 APGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
AP T +K P + A + P P ++ T PE
Sbjct: 483 AP-----------------TTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPE--- 520
Query: 278 GRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYS 337
+ E + ++ N + P +P P K P ET+ +
Sbjct: 521 -----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAPTTPKETAPT 573
Query: 338 AQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKA 397
KG A PTT EP PK KP+ + P T +PT
Sbjct: 574 TP-KGTA--PTT--------------LKEPAPTTPK--KPAPKELAPTTTK---EPTSTT 611
Query: 398 KDKQAVS---GQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGP 454
DK A + G A P+T K K A +L +P + K P
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK------GTAPTTLKEPAPTTPKKPAP 665
Query: 455 VATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEP 514
P +G P P P K+ P P P P P T PE
Sbjct: 666 KELAPTTTKG---PTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAP------TTPET 715
Query: 515 LKNESPVISAPVKDQGP-SVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQ 573
+ +S P + P ++ P +P + A+ P++L + P+ P +
Sbjct: 716 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL-ENSPKEPGVPTTK 768
Query: 574 APMVPAP 580
P P
Sbjct: 769 TPAATKP 775
Score = 31.2 bits (69), Expect = 4.0
Identities = 76/450 (16%), Positives = 124/450 (27%), Gaps = 36/450 (8%)
Query: 31 TKYSEATEHPGAP--PQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG 88
TK T AP P+ P P +PA P A +PA A T P
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 89 PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDA 148
PT ++PA + P P + + PE E
Sbjct: 460 PTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 149 PFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQA 208
P E P P + P P + +A + P PK + + P
Sbjct: 519 PEE------------PTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 209 AAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP------LP 262
+ G A A ++ ++ P + P P
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 263 AAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQ 322
+ T P+ ++E + E T P KP
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 685
Query: 323 YKPPDDKMVHETSYSAQFKGEASKPTTAD---------NKVIDRRRIRSLYSEPFKEPPK 373
P + A + PTT + + + +++ P + P+
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745
Query: 374 VE---KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
+ P + PK+ T A + + AK K+ E T P+ + +M
Sbjct: 746 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT--TAKDKTTERDLRTTPETTTAAPKM 803
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPD 460
+ A E + ++ TQ T D
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQD 833
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 88.2 bits (217), Expect = 3e-17
Identities = 123/521 (23%), Positives = 183/521 (35%), Gaps = 53/521 (10%)
Query: 318 KAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVIDRRRIRSLYSEPFKEPPKVEK 376
K KP KPP + FK TT NKV +I + ++P P +
Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLP- 172
Query: 377 PSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK--L 434
P+ +SK + + + T + K+ + K+ S +G T + QS E + L
Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTN----KQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 435 AEAKESLAQPVSDS-SKTQGPVATEPD-------KDQGSVVPG-----LLKGQGPMVQEP 481
A + LA+P + + T+GP T P K+ S P +K +EP
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 482 LKKQGSVVPGPPKDLGPMI---PLPVKDQDHTVPEPLKNESPVI--SAPV--KDQGPSVP 534
P PK+ P P P ++ P K +P SAP K+ P+ P
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 535 VPPKNQSPMVPAKV--KDQGSVVPE----SLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P +P PA K+ P+ + K+ P P+ AP PAP + P
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP-A 406
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPK 648
+ K+ P + P PAP + P K+ P + P P+ P
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS--APTTTKEPAPTTTKSA----PTTPKEPS 460
Query: 649 DESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
+ AP + + P K P P+ + AP + P
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEPAPTTTKKPAPTTPKEPA 516
Query: 709 VPESVKNQDPILPVLVKDQGPTVLQP--PKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPV 766
P + K P P + P L P P+ PE L P P P ++P P
Sbjct: 517 -PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 574
Query: 767 PAKDQGPAVPEPLKTQGPRDPQLPTVS-PLPRVMIPTAPHT 806
K P P+ P++P T P P TAP T
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615
Score = 84.0 bits (206), Expect = 5e-16
Identities = 122/531 (22%), Positives = 176/531 (33%), Gaps = 59/531 (11%)
Query: 298 SSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVID 356
S++ N+ I KPI +P PP+ ETS + + +K TT NK
Sbjct: 146 STTQHNKVSTSPKITTAKPINPRPSL-PPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204
Query: 357 RRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGP 416
S KE +EK S + P + KPT KA+ G A P
Sbjct: 205 TDGKEKTTSA--KETQSIEKTSAKDLAPTSKVLA-KPTPKAET--TTKGPALTTPKEPTP 259
Query: 417 STTKPDDKEQSKEMN-NKLAEAKESLAQPVSDSSKTQGPVATEP----DKDQGSVVPGLL 471
+T K KE + A + +P ++K+ EP K+ P
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--- 316
Query: 472 KGQGPMV-QEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG 530
K P +EP P PK+ P P P P + P + P K+
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPA 375
Query: 531 PS----VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
P+ P PK +P P K P+ P+ P P + P P K+ P
Sbjct: 376 PTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKEPAP 431
Query: 587 MVSAS----VKDQGPMV--SAPV--KDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKD 638
+ S K+ P SAP K+ P P PAP + P + P K+
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KE 490
Query: 639 QDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAV 698
P P+ P + AP + + P K+ P+
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTP------------KETAPTTPKKLTPTTPEK 538
Query: 699 VAPV--KNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVP 756
+AP + P PE + P P + P P EP P P P
Sbjct: 539 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-TPKEPAP 597
Query: 757 LKDQDPLVPVPAKDQGPAVPE-----PLKTQGPRDPQLPTVSPLPRVMIPT 802
++P P K+ P P+ LK P P+ P P+ + PT
Sbjct: 598 TTPKEP-APTTPKETAPTTPKGTAPTTLKEPAPTTPK----KPAPKELAPT 643
Score = 63.2 bits (152), Expect = 1e-09
Identities = 131/608 (21%), Positives = 187/608 (30%), Gaps = 70/608 (11%)
Query: 60 PSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTS--GPA 117
P+++ +A T A+ A T P PT +EPA+ + + S T+ PA
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 118 DSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP 177
+ + K P + P AP + ++ P + P PK
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 178 VQISAASQASAPILGAPKRRPQSQERWPVQAAAE---AREQEAAPGGAGGLAAGKASGAD 234
A + P PK + + P E +E AP A A
Sbjct: 350 ---PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEP 405
Query: 235 ERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVA 294
T ++ P + E P A P ++A
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA---------PTTP 456
Query: 295 SAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKV 354
S + E T +P KP P + A + PTT
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP---- 512
Query: 355 IDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAE 414
EP PK P+ T PT K + A + E
Sbjct: 513 ----------KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPE 561
Query: 415 GPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVA-TEP-DKDQGSVVPGLLK 472
P+ T P++ + A A + +P + K P EP P K
Sbjct: 562 EPTPTTPEEPAPT----TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617
Query: 473 GQGPMVQEPLKKQGSVVP--GPPKDLGPMIPLPVKDQDHTVPEPLKN--ESPVISAPVKD 528
G P LK+ P PK+L P T EP + P + P K
Sbjct: 618 GTAPTT---LKEPAPTTPKKPAPKELAPT----------TTKEPTSTTCDKPAPTTP-KG 663
Query: 529 QGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV 588
P+ P P +P PA +G+ P +LK+ P P K AP AP +GP
Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGT-APTTLKEPAPTTP---KKPAPKELAPTTTKGPTS 719
Query: 589 SASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGP-----MVSAPIKDQDPMV 643
+ S K P + P K+ P P P PAP E P VS P ++P
Sbjct: 720 TTSDK---PAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 775
Query: 644 PEHPKDES 651
DES
Sbjct: 776 IHKSPDES 783
Score = 38.1 bits (87), Expect = 0.033
Identities = 49/239 (20%), Positives = 69/239 (28%), Gaps = 26/239 (10%)
Query: 586 PMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPE 645
P A +GP ++ P K+ P P P P P + SAP ++P
Sbjct: 238 PTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTT----IKSAPTTPKEPA--- 289
Query: 646 HPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQ 705
P + T P + + EP P + E A + K
Sbjct: 290 -PTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 706 GPVVPESVKNQDPI----------LPVLVKDQGPTVLQP-PKNQGRIVPEPLKNQVPIVP 754
P P+ P P K+ PT +P P P K P P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 755 VPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
P P P + P+ P + PT + P + T E SP
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461
Score = 37.4 bits (85), Expect = 0.056
Identities = 116/547 (21%), Positives = 166/547 (30%), Gaps = 106/547 (19%)
Query: 38 EHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAA 97
+ P + P P +PA P A +PA A T P PT +EPA
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431
Query: 98 GPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQ 157
+S P +T PA + + K EPS E P+ T +
Sbjct: 432 TTTKSAP------TTTKEPAPTTTKSAPTTPK----EPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 158 KDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEA 217
K P P P P + A + P PK A +E
Sbjct: 482 K-----PAPTTPKEP-APTTPKEPAPTTTKKPAPTTPKE------------PAPTTPKET 523
Query: 218 APGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
AP T +K P + A + P P ++ T PE
Sbjct: 524 AP-----------------TTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPE--- 561
Query: 278 GRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYS 337
+ E + ++ N + P +P P K P ET+ +
Sbjct: 562 -----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP--KEPAPTTPKETAPT 614
Query: 338 AQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKA 397
KG A PTT EP PK KP+ + P T +PT
Sbjct: 615 TP-KGTA--PTT--------------LKEPAPTTPK--KPAPKELAPTTTK---EPTSTT 652
Query: 398 KDKQAVS---GQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGP 454
DK A + G A P+T K K A +L +P + K P
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK------GTAPTTLKEPAPTTPKKPAP 706
Query: 455 VATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEP 514
P +G P P P K+ P P P P P T PE
Sbjct: 707 KELAPTTTKG---PTSTTSDKPAPTTP-KETAPTTPKEPAPTTPKKPAP------TTPET 756
Query: 515 LKNESPVISAPVKDQGP-SVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQ 573
+ +S P + P ++ P +P + A+ P++L + P+ P +
Sbjct: 757 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE------PTPKAL-ENSPKEPGVPTTK 809
Query: 574 APMVPAP 580
P P
Sbjct: 810 TPAATKP 816
Score = 31.2 bits (69), Expect = 4.0
Identities = 76/450 (16%), Positives = 124/450 (27%), Gaps = 36/450 (8%)
Query: 31 TKYSEATEHPGAP--PQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG 88
TK T AP P+ P P +PA P A +PA A T P
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 89 PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDA 148
PT ++PA + P P + + PE E
Sbjct: 501 PTTTKKPAPTTPKE-PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 149 PFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQA 208
P E P P + P P + +A + P PK + + P
Sbjct: 560 PEE------------PTPTTPEEP-APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 209 AAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP------LP 262
+ G A A ++ ++ P + P P
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 263 AAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQ 322
+ T P+ ++E + E T P KP
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 726
Query: 323 YKPPDDKMVHETSYSAQFKGEASKPTTAD---------NKVIDRRRIRSLYSEPFKEPPK 373
P + A + PTT + + + +++ P + P+
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786
Query: 374 VE---KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
+ P + PK+ T A + + AK K+ E T P+ + +M
Sbjct: 787 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT--TAKDKTTERDLRTTPETTTAAPKM 844
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPD 460
+ A E + ++ TQ T D
Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQD 874
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 84.7 bits (208), Expect = 3e-16
Identities = 177/785 (22%), Positives = 243/785 (30%), Gaps = 98/785 (12%)
Query: 46 PPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAP-GPTGEREPAAGPGRSGP 104
P P ++P A + + QG D+ A P P P G P+A S
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 105 GPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWP 164
G L T P SV+ + P P P S R T K A P
Sbjct: 877 GVTLPPKET--PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 165 LPRRGDHP------------------WIPKPVQISAASQASAPILGAPKRRPQSQERWPV 206
P+ P W P P + S P +PK P P
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP- 993
Query: 207 QAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQA 266
P GG A GA P + + TP P +
Sbjct: 994 ------------PSPKGGPATPSPKGAPT--------PPAVTPPSPKGSPAATPFPKGAS 1033
Query: 267 QVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPP 326
A P + +G AA L + A+ + S P P P P
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS---P 1090
Query: 327 DDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPK- 385
+ A A+ P+ + + P PP K + + PK
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHK--GAPTTPAATPPS-PKGGLATPPPKG 1147
Query: 386 --KTSASHKPTRKA-----KDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAK 438
T A+ P+ K K A + AA S +G T P K K
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPK 1206
Query: 439 ESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQG--PMVQEPLKKQGSVVPGPPKDL 496
LA P + T P AT P G P KG P P K G P P
Sbjct: 1207 GGLATPSPKGAPTT-PAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 497 GPMIPLPVKDQDHTVPEPLKNE-SPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVV 555
P P + P K +P + P +G PPK +P PA
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-APTPPA-------AT 1316
Query: 556 PESLKDQGPRIPEPVKNQAPMVPAPVKDEG-PMVSASVKDQGPMVSAPVKDQGPIVPAPV 614
P S K P P P P P +G P + A+ P GP P+
Sbjct: 1317 PPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATT---------PSSKGGPTTPSSK 1366
Query: 615 KGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGL 674
+G P P GP ++ P + P +P D ++ A P+ + + + PV +G
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-PVTREG- 1424
Query: 675 VVSGPVKDQDVVVPEHAKVH-DSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQ 733
+ P K D+ P V A GP P S DP LP + P+ +
Sbjct: 1425 -AATPSKG-DLTPPAVTPVSLKKAPATSAPKGGPATPSS--KGDPTLPAVTP---PSPKE 1477
Query: 734 PPKNQGRIVPEPLKNQVPIVPVPLKDQD-PLVPVPAKDQGPAVPEPLKTQGPRDPQLPTV 792
PP + ++ + P P P+ P V + + PA P RDP PT
Sbjct: 1478 PPAPK-QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP-----SSRRDPIAPTA 1531
Query: 793 SPLPR 797
+ L +
Sbjct: 1532 TLLSK 1536
Score = 78.2 bits (191), Expect = 3e-14
Identities = 195/870 (22%), Positives = 266/870 (30%), Gaps = 143/870 (16%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P P P PA+ PPS + T +G A AT P+P + P
Sbjct: 998 GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-ATPPSPKGSPAATPLPKGA 1056
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDF 160
+ P L S GPA ++ P P P + P AP
Sbjct: 1057 PTTPAATLPSPK-GGPATPSLKGAPTPPAATPPSPKGGPATP-SPKGAPMPPAATPPSPK 1114
Query: 161 RAWPLPRRGDHPWIPKPVQISA-ASQASAPILGAPKR------RPQSQERWPVQAAAEAR 213
P P P S A+ P GAP P+ P A
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 214 EQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGP 273
P GGLA GA P G TP P A P
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPK---------GGLATPSPKGAPTTPAATP 1225
Query: 274 EAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHE 333
+ +G A + A+ S + P K P PP K
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSP------KGGPATPPPKGAPTPPAATPPSLKGGLA 1279
Query: 334 TSYSAQFKGEA--------SKPTTADNKVIDRRRIRSLYS---EPFKEPPK--VEKPSVQ 380
T A P T+ K + S P PPK P+V
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Query: 381 SSKPKKTSASHKPTRKAK-------DKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK 433
PK T T +K K+ + AA GP+ T P K + + +
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK-RGPAIPSP 1398
Query: 434 LAEAKESLAQPVSDSSKTQGPVATEP-------DKDQGSVVPGLLKGQGPMVQEPLKKQG 486
+ P+S PV E D +V P LK + P P K G
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK-KAPATSAP--KGG 1455
Query: 487 SVVPG-----------PPKDLGPMIPLPVKDQDH-----TVPEPLKNESPVISAPVKDQG 530
P PP P P V P P+ +P + A +
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG--APTLPAVIPSSP 1513
Query: 531 PSVPVPPKNQ-SPMVPAKV----KDQGSVVP-ESLKDQGPRIPEPVKNQAPMVPAPVKDE 584
VP P ++ P+ P K ++ P E+L +P P K P +P P E
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT--PAIPTP--KE 1569
Query: 585 GPMVSASVKDQGPMVSAPVKDQG----------PIVPAPVKGEGPIVPA---PVKDEGPM 631
P +S + P P +G P V +P E P PA P ++GP
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 632 VSAP--IKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVS-GPVKDQDVVV- 687
AP P+ P KD + G+ V P ++GL GP ++V+V
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV--PQASKGLPAKKGPTALKEVLVA 1687
Query: 688 --PEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEP 745
PE + + AP + +GP +S PI P P G P
Sbjct: 1688 PAPESTPI----ITAPTR-KGPQTKKSSATSPPICP-----------DPSAKNGSKGPLS 1731
Query: 746 LKNQVPIVPVP------LKDQD-------PLVPVPAKDQGP--------AVPEPLKTQGP 784
P++PV K +D PL P +K P +P+P
Sbjct: 1732 TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS 1791
Query: 785 RDPQLPTVSPLPRVMIPT-APHTEYIESSP 813
P P PL +PT P +++ SSP
Sbjct: 1792 AAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821
Score = 69.3 bits (168), Expect = 1e-11
Identities = 197/906 (21%), Positives = 279/906 (30%), Gaps = 170/906 (18%)
Query: 22 ADIAVPLVFTKYSEATEHPGAPPQPPPPQQQA------QPALAPPSARAVAIETQPAQGE 75
A +A ++ + ++ P PP PP + ALAP ++ T+ +
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
Query: 76 LDAVARAT----GPAPGPTG------EREPAAGPGRSGPGPGLG--SGSTSGPADSVMRQ 123
A ++ T +P P G + P G +GP +G S S S + +
Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPE 838
Query: 124 DYRAWKVQRPEPSC-------RPRSEYQPSDA-----------PFERETQYQKDFRAWPL 165
+ +++ + P+ P+ PS P E T + P
Sbjct: 839 NSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL---PF 895
Query: 166 PRRGDHPWIPKPVQISAASQASA--------------PILGAPKRRPQSQERWPVQAA-- 209
P+ G P P P Q A S S+ P +PK P P
Sbjct: 896 PKEG--PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 210 --------AEAREQEAAPGGAGGLAAGKASGADERDTRR----KAGPAW----------- 246
A P GG A GA K GPA
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 247 IVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFR 306
+ + TP P + A P + +G AA L + A+ + S
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 307 AWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSE 366
P P P P + A A+ P+ + +
Sbjct: 1074 PSLKGAPTPPAATPPS---PKGGPATPSPKGAPMPPAATPPSPKGGLATPPH--KGAPTT 1128
Query: 367 PFKEPPKVEKPSVQSSKPK---KTSASHKPTRKA-----KDKQAVSGQAAKKKSAEGPST 418
P PP K + + PK T A+ P+ K K A + AA S +G
Sbjct: 1129 PAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 419 TKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKG--QGP 476
T P K K LA P + T P AT P G P KG P
Sbjct: 1188 T-PSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGLATPS-PKGAPTTP 1244
Query: 477 MVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKN-ESPVISAPVKDQGPSVPV 535
P K G P P P P + P K +P + P +G
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 536 PPKNQSPMVPAKVKDQGSVVPESLKDQG----PRIPEPVKNQAPMVPA-----------P 580
PPK +P PA P + +G P + P P +PA P
Sbjct: 1305 PPKG-APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 581 VKDEGPMVSASVKDQ--GPMVSAPVKDQGPIVPAPVKGEGPIVPA------------PVK 626
EGP A+ GP ++ P +GP +P+P KG+ P PA PV
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP-KGD-PTSPAVIPLSPKKAPATPVT 1421
Query: 627 DEG----------PMVSAPIKDQDPMVPEHPKDESAM------ATAPIKNQGSMVSEPVK 670
EG P P+ + PK A T P S P
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 671 NQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILP--VLVKDQG 728
Q S P K P A AV+ + P P S +DPI P L+ +
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTL-PAVIPSSPKEVPATPSS--RRDPIAPTATLLSKKT 1538
Query: 729 PTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQ 788
P L P + ++P P + VP + P +P P + PA P + P
Sbjct: 1539 PATLAPKE---ALIP-------PAMTVPSPKKTPAIPTP--KEAPATPSSKEASSP---- 1582
Query: 789 LPTVSP 794
P V+P
Sbjct: 1583 -PAVTP 1587
Score = 65.1 bits (157), Expect = 3e-10
Identities = 169/771 (21%), Positives = 240/771 (31%), Gaps = 127/771 (16%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P P PA PPS + P A P GP A
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRP-RSEYQPSDAPFERETQYQKD 159
+ P L G + P V P P P S + + P K
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAV----VTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 160 FRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAA- 218
P P+ P P ++ S P L P P S+ ++ E AA
Sbjct: 1323 SPGTPPPKGA-----PTPPAVTPPSPKGTPTL--PATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 219 PGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRG 278
P GG A S K GPA + +G +P + + AT P G
Sbjct: 1376 PSHKGGPAMTPPS--------PKRGPA--IPSPKGDPTSPAVIPLSPKKAPAT-PVTREG 1424
Query: 279 RAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSA 338
A P K P P K TS
Sbjct: 1425 AAT-------------------------------PSKGDLTPPAVTPVSLKKAPATSAP- 1452
Query: 339 QFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAK 398
KG + P++ + + + P + P K SS PKK A+ P A
Sbjct: 1453 --KGGPATPSSKGDPTL------PAVTPPSPKEPPAPKQVATSSSPKKAPATPAP-MGAP 1503
Query: 399 DKQAVSGQAAKKKSAEGPSTTK----PDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGP 454
AV + K+ A PS+ + P SK+ LA KE+L P +
Sbjct: 1504 TLPAVIPSSPKEVPAT-PSSRRDPIAPTATLLSKKTPATLA-PKEALIPPAMTVPSPKKT 1561
Query: 455 VATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEP 514
A P + P + P P +G+ P P + L P P P P
Sbjct: 1562 PAI-PTPKEAPATPSSKEASSPPAVTPSTYKGA--PSPKELLIP--PAVTSPSPKEAPTP 1616
Query: 515 LKNESPVISAPVKDQGPSVPVP--PKNQSPMVPAKVKD-----------QGSVVPESLKD 561
P ++ P ++GP+ P P P+ P+ +KD G+ VP++ K
Sbjct: 1617 -----PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671
Query: 562 QGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIV 621
+ + + PAP + P+++A + +GP PI P P G
Sbjct: 1672 LPAKKGPTALKEVLVAPAP--ESTPIITAPTR-KGPQTKKSSATSPPICPDPSAKNGS-- 1726
Query: 622 PAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVK 681
P+ P P++ +D KD S P+ S S P+
Sbjct: 1727 KGPLSTVAPAPLLPVQ-KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF------- 1778
Query: 682 DQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQG-- 739
+ V+P+ SA +P + P+ P V P L G + P K
Sbjct: 1779 --EKVLPKPESASVSAAPSPPVSL-PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 740 -------RIVPEPLKNQVPIVPVPLKDQDPLVPVPA-KDQGPAVPEPLKTQ 782
I PEP+ VP Q LV +P K G VP P Q
Sbjct: 1836 DEDELLPLIPPEPISGGVPF-------QSVLVNMPTPKSAGIPVPTPSAKQ 1879
Score = 65.1 bits (157), Expect = 3e-10
Identities = 176/743 (23%), Positives = 252/743 (33%), Gaps = 147/743 (19%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELD-AVARATGPAPGP-TGEREPAA 97
P P PPP+ P A P + + T P +G + AV P GP T + A
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 98 GPGRSGPGPGLGSGSTSGP--ADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERE-- 153
P + P GS T P A + + K P+ P S+ P+ P +E
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT-TPSSKEGP 1369
Query: 154 -----TQYQKDFRAW--PLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPV 206
T K A P P+RG P IP P + S A P+ +PK+ P + PV
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRG--PAIPSP-KGDPTSPAVIPL--SPKKAPAT----PV 1420
Query: 207 --QAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAA 264
+ AA + + P ++ KA + K GPA TP
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPAT----SAPKGGPA-------------TPSSKG 1463
Query: 265 QAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKP----IKAK 320
+ A P + + A + A SSS + P P
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQV----------ATSSSPKK--------APATPAPMGAPTL 1505
Query: 321 PQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQ 380
P P K V T S + P ++ ++ +L + PP + PS
Sbjct: 1506 PAVIPSSPKEVPATPSSRR------DPIAPTATLLSKKTPATLAPKEALIPPAMTVPS-- 1557
Query: 381 SSKPKKTSASHKPTRKAKDKQAV-SGQAAKKKSAEGPSTTK--PDDKEQSKEMNNKLAEA 437
PKKT A P K+ A S + A A PST K P KE
Sbjct: 1558 ---PKKTPAIPTP----KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610
Query: 438 KESLAQP-VSDSSKTQGPVATEPDKDQGS--VVPGLLKGQGPMVQEPLKKQGSVVPGPPK 494
KE+ P V+ S +GP P S V P LK K G+ VP K
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670
Query: 495 DL-GPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGS 553
L P +K+ + P +P+I+AP + +GP P+ P GS
Sbjct: 1671 GLPAKKGPTALKE---VLVAPAPESTPIITAPTR-KGPQTKKSSATSPPICPDPSAKNGS 1726
Query: 554 VVPESLKDQGPRIP--EPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVP 611
P S P +P + A A +GP+ K P+ +A + ++P
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE---KVLP 1783
Query: 612 APVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKN 671
P P+ P VS P+ VP P + + ++P
Sbjct: 1784 KPESASVSAAPS------PPVSLPLAPSP--VPTLPPKQQFLPSSP-------------- 1821
Query: 672 QGLVVSGPVK-----DQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKD 726
GLV+ P K D+D ++P + PE + P VLV
Sbjct: 1822 -GLVLESPSKPLAPADEDELLP------------------LIPPEPISGGVPFQSVLVN- 1861
Query: 727 QGPTVLQPPKNQGRIVPEPLKNQ 749
+ PK+ G VP P Q
Sbjct: 1862 -----MPTPKSAGIPVPTPSAKQ 1879
Score = 43.5 bits (101), Expect = 8e-04
Identities = 129/583 (22%), Positives = 185/583 (31%), Gaps = 106/583 (18%)
Query: 25 AVPLVFTKYSEATEHP-GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARAT 83
AV V K + AT P G P P PA+ PPS + Q A A AT
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 84 G--------PAPGPTGERE-PAAGPGRSGP-GPGLGSGSTSGPADSVMRQDYRAWKVQRP 133
PA P+ +E PA R P P S PA ++ + P
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 134 EPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGA 193
P P P +AP T K+ + P + P P ++ ++P +
Sbjct: 1557 SPKKTPAIP-TPKEAP---ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP---S 1609
Query: 194 PKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEG 253
PK P P + A P G + + + +D+
Sbjct: 1610 PKEAPTP----PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS--------------- 1650
Query: 254 LGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKP 313
T + ++ AT P+A +G A VA A S+
Sbjct: 1651 ----PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST------------- 1693
Query: 314 VKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPK 373
PI P K P K K A+ P + L +
Sbjct: 1694 --PIITAPTRKGPQTK-----------KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740
Query: 374 VEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK 433
V+K S +++K K ASH P A + A P T +K K +
Sbjct: 1741 VQKDSSKTAKGK--DASHSPK---------GPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 434 LAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPP 493
++ A + PVS PV T P K Q L G +++ P K + P
Sbjct: 1790 VSAAP---SPPVS-LPLAPSPVPTLPPKQQ-----FLPSSPGLVLESPSK---PLAPADE 1837
Query: 494 KDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGP-SVPVPPKNQSPMVPAKVKDQG 552
+L P+IP PEP+ P S V P S +P S P ++G
Sbjct: 1838 DELLPLIP----------PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKG 1887
Query: 553 SVVPESLKDQGPRIPE-----PVKNQAPMVPAPVKDEGPMVSA 590
S + P + E QA + A DE P+ A
Sbjct: 1888 SGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
Score = 43.1 bits (100), Expect = 0.001
Identities = 78/315 (24%), Positives = 117/315 (37%), Gaps = 39/315 (12%)
Query: 520 PVISAPVKDQGPSVP--VPPKNQSPMVPAKVKDQGSVVPESLKDQGPR-IPEPV------ 570
PV+++ K GP+ P P S + P GSV + L GP + +P
Sbjct: 284 PVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSV--QLLGQTGPSALSDPTVKTISV 341
Query: 571 ---------KNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPV--KGEGP 619
+Q ++P P+ +V A+V P+V AP D+GP + + G
Sbjct: 342 DHSSTGASYPSQRSVIP-PLPSRNEVVPATVA-AFPVV-APSVDKGPSTISSITCSPSGS 398
Query: 620 IVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGP 679
+ A P S +K +P +A P+ + G+ V N + + P
Sbjct: 399 LNVATSFSLSPTTSLILKSSPNATYHYP----LVAQMPVSSVGT-TPLVVTNPCTIAAAP 453
Query: 680 VKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQG 739
+V V P+ N P P ++ P+ P Q T L+ P +
Sbjct: 454 TTTFEVATC----VSPPMSSGPISNIEPTSPAALV-MAPVAPKEPSTQVATTLRIPVSPP 508
Query: 740 RIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQG-PAVPEPLKTQGPRDPQLPTVSPLPRV 798
PE LKN V V Q L VPA +G P P +D PTV PL +
Sbjct: 509 LPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKD---PTVLPLVQA 565
Query: 799 MIPTAPHTEYIESSP 813
+P + SSP
Sbjct: 566 APKNSPSFQSTSSSP 580
Score = 40.8 bits (94), Expect = 0.005
Identities = 119/556 (21%), Positives = 171/556 (30%), Gaps = 91/556 (16%)
Query: 309 TDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPF 368
T + I P P+D +S +F PT D + + SL PF
Sbjct: 495 TQVATTLRIPVSPPLPDPEDLKNLPSSVLVKF------PTQKDLQTVPA----SLEGAPF 544
Query: 369 ---------KEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGP--- 416
K+ P V P VQ++ K S S + T + + KKS P
Sbjct: 545 SPAQAGLTTKKDPTV-LPLVQAAP--KNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI 601
Query: 417 -----STTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEP--DKDQGSVVPG 469
S T P S + + A A P+ SS VA P D V P
Sbjct: 602 GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT 661
Query: 470 LLKGQGPMVQEPLK-KQGSVVPGP---PKDLGPMIPLPVKDQDHTVPEPLKNESPVISAP 525
KG +G+V P P G + LP+ VP +N PV +P
Sbjct: 662 TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL------VPTASEN-CPVAPSP 714
Query: 526 VKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPA------ 579
Q P+ +P +P V +P + G + + + + + + P
Sbjct: 715 ---QNTCAPLATLVLAPEIPKSVPSPS--LPPAGTPPGTKKVDGISHTSALAPVASSPKE 769
Query: 580 -PVKDEGPMVSASVK-------DQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPM 631
P +D G +AS K D + V Q P GP P G +
Sbjct: 770 CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI-----GNL 824
Query: 632 VSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHA 691
S + +PE+ +P P P+ + V +P
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
Query: 692 KVHDSAVVAPVKNQGPVVPE-------SVKNQDPI----------LPVLVKDQG----PT 730
S V P +GP P S+ + P +P +G P
Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944
Query: 731 VLQPPKNQGRIVPEPLKNQVPIVPVPLKDQD-PLVPVP-AKDQGPAVPEPLKTQGPRDPQ 788
P G P P P P + P P P PA P GP P
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 789 LPTVSPLPRVMIPTAP 804
P +P P + P +P
Sbjct: 1005 -PKGAPTPPAVTPPSP 1019
Score = 32.0 bits (71), Expect = 2.4
Identities = 87/428 (20%), Positives = 144/428 (33%), Gaps = 80/428 (18%)
Query: 451 TQGPVATEPDKDQGSVVPGLLKGQGPM-VQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDH 509
T+ ATE + Q +L + V L + G +P P PL +Q
Sbjct: 6 TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
Query: 510 TVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKD--QGSVVPESLKDQGPRIP 567
P P S + P Q S P +P P + + + P +L P I
Sbjct: 66 PFPSPSTIASTPLEVPF-PQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 568 EPVK----NQAPMV---------------PAPVKDEGPMVSASVKDQGPMVSAPVKDQGP 608
+K + AP+ P + P V+ + +SAP+ P
Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP 184
Query: 609 ----------IVPAPVKGEGP---IVPAPVKDEGPMVSAPIKDQDPMVPE-HPKDESAMA 654
+VP P P + P PM S I+ +P+ P A+A
Sbjct: 185 KTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMAS--IQSGVASLPQTTPTTTLAIA 242
Query: 655 TAPIKNQ--GSMVSEPVKNQGLVVSGPVK----------------------------DQD 684
+ +K+ S++ P L + GPV D
Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFP 302
Query: 685 VVVPEH-AKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVP 743
+ + H A +H S+ V+ G P ++ DP + + D T P + I P
Sbjct: 303 ISLGSHLAPLHQSS-FGSVQLLGQTGPSAL--SDPTVKTISVDHSSTGASYPSQRSVIPP 359
Query: 744 EPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPT---VSPLPRVMI 800
P +N+V VP V P+ D+GP+ + + T +SP +++
Sbjct: 360 LPSRNEV----VPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLIL 415
Query: 801 PTAPHTEY 808
++P+ Y
Sbjct: 416 KSSPNATY 423
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 80.9 bits (198), Expect = 4e-15
Identities = 115/351 (32%), Positives = 135/351 (38%), Gaps = 41/351 (11%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLP 503
P +K QGP + P K QG G + QGP P K QG G K GP P P
Sbjct: 40 PPQGGNKPQGP-PSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGP--PPP 95
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
K Q P+ K+ SP S P K QGP PP+ + + QG P K QG
Sbjct: 96 GKPQGPP-PQGDKSRSPR-SPPGKPQGP----PPQGGN-------QPQGPPPPPG-KPQG 141
Query: 564 PRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPA 623
P K Q P P P K +GP K + S P K QGP + +GP P
Sbjct: 142 PPPQGGNKPQGP--PPPGKPQGPPPQGDNKSRSSR-SPPGKPQGPPPQGGNQPQGP-PPP 197
Query: 624 PVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQ 683
P K +GP K Q P P P+ K+Q + S P K QG G + Q
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN--KSQSAR-SPPGKPQGPPPQGGNQPQ 254
Query: 684 DVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVP 743
P P K QGP K Q P P K QGP K++ P
Sbjct: 255 GPPPP------------PGKPQGPPPQGGNKPQGP--PPPGKPQGPPPQGGSKSRSSRSP 300
Query: 744 EPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSP 794
P K Q P + Q P P P K QGP K QGP P P P
Sbjct: 301 -PGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 349
Score = 78.6 bits (192), Expect = 2e-14
Identities = 111/372 (29%), Positives = 128/372 (34%), Gaps = 53/372 (14%)
Query: 444 PVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLP 503
P K QGP +K QG PG K QGP Q + PG P+ GP P
Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDKSRSPRSPPGKPQ--GPP-PQG 125
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV--------KDQGSVV 555
P P K + P K QGP P P+ P K K QG
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185
Query: 556 PESLKDQGPRIPEPVKNQAPMV---------PAPVKDEGPMVSASVKDQGPMVSAPVKDQ 606
+ QGP P P K Q P P P K +GP K Q S P K Q
Sbjct: 186 QGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR-SPPGKPQ 243
Query: 607 GPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVS 666
GP + +GP P P K +GP K Q P P P+ + + S S
Sbjct: 244 GPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR---SSRS 299
Query: 667 EPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKD 726
P K QG G + Q P P K QGP K Q P P K
Sbjct: 300 PPGKPQGPPPQGGNQPQGPPPP------------PGKPQGPPPQGGNKPQGP--PPPGKP 345
Query: 727 QGP---------TVLQPP-KNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVP 776
QGP + PP K QG E Q P P Q P P + QGP P
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Query: 777 EPLKTQGPRDPQ 788
P + R PQ
Sbjct: 406 -PQGGRPSRPPQ 416
Score = 53.5 bits (127), Expect = 8e-07
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 9/257 (3%)
Query: 366 EPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKE 425
+P PP+ + S +SS+ P + Q K + KP
Sbjct: 158 KPQGPPPQGDNKS-RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216
Query: 426 QSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQ 485
+ + S K QGP ++ QG P K QGP Q K Q
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGNKPQ 275
Query: 486 GSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVP 545
G PG P+ GP K + P P K + P + QGP P P K Q P
Sbjct: 276 GPPPPGKPQ--GPPPQGGSKSRSSRSP-PGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQ 331
Query: 546 AKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKD 605
K QG P K QGP K+++ P P K +GP QGP A
Sbjct: 332 GGNKPQGPPPPG--KPQGPPPQGGSKSRSARSP-PGKPQGPPQQEGNNPQGPPPPAGGNP 388
Query: 606 QGPIVPAPVKGEGPIVP 622
Q P P + +GP P
Sbjct: 389 QQPQAPPAGQPQGPPRP 405
Score = 52.8 bits (125), Expect = 1e-06
Identities = 72/279 (25%), Positives = 87/279 (31%), Gaps = 38/279 (13%)
Query: 316 PIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVE 375
P KPQ PP +S S K + P + +P PP
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN--------------QPQGPPPPPG 199
Query: 376 KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLA 435
KP Q P+ + P K + K +SA P Q
Sbjct: 200 KP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG-- 255
Query: 436 EAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
P K QGP +K QG PG K QGP Q K + S P P K
Sbjct: 256 --------PPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGGSKSRSSRSP-PGKP 304
Query: 496 LGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV------- 548
GP P P P K + P K QGP P P+ P +K
Sbjct: 305 QGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPP 363
Query: 549 -KDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
K QG E QGP P Q P P + +GP
Sbjct: 364 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402
Score = 49.7 bits (117), Expect = 1e-05
Identities = 80/271 (29%), Positives = 89/271 (32%), Gaps = 68/271 (25%)
Query: 527 KDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
K QGP P P K Q P + QG P K QGP K Q P P P K +GP
Sbjct: 46 KPQGPPSP-PGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGNKPQGP--PPPGKPQGP 101
Query: 587 MVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
K + P S P K QGP + +GP P P K +GP K Q P P
Sbjct: 102 PPQGD-KSRSPR-SPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGK 158
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
P QG G K + P P K QG
Sbjct: 159 P------------------------QGPPPQGDNKSRSSRSP------------PGKPQG 182
Query: 707 PVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPV 766
P P NQ QGP P P K Q P K Q P P
Sbjct: 183 P--PPQGGNQP---------QGPP------------PPPGKPQGPPPQGGNKPQGP--PP 217
Query: 767 PAKDQGPAVPEPLKTQGPRDPQLPTVSPLPR 797
P K QGP K+Q R P P P+
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Score = 44.7 bits (104), Expect = 4e-04
Identities = 61/257 (23%), Positives = 84/257 (32%), Gaps = 29/257 (11%)
Query: 34 SEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGER 93
S ++ P PQ PPPQ QP PP P G G GP +
Sbjct: 170 SRSSRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228
Query: 94 EPAAGPGRSGPG-----PGLGSGSTSGPADSVMRQD----YRAWKVQRPEPSCRPRSEYQ 144
+ + RS PG P G GP + K Q P P +P+
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-P 287
Query: 145 PSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP----VQISAASQASAPILGAPKRRPQS 200
P R ++ P P+ G+ P P P Q + P P +PQ
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 347
Query: 201 QERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP 260
P Q +++R + P GK G +++ GP A G +
Sbjct: 348 P---PPQGGSKSRSARSPP--------GKPQGPPQQEGNNPQGPP---PPAGGNPQQPQA 393
Query: 261 LPAAQAQVQATGPEAGR 277
PA Q Q P+ GR
Sbjct: 394 PPAGQPQGPPRPPQGGR 410
Score = 36.6 bits (83), Expect = 0.096
Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 19/198 (9%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQG-----ELDAVARATGPAPGPTGERE 94
P PQ PPPQ QP PP + P QG + GP P R
Sbjct: 53 PPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 110
Query: 95 PAAGPGRSGPGPGLGSGSTSGPADSVMRQD----YRAWKVQRPEPSCRPRSEYQPSDAPF 150
P + PG+ P G GP + K Q P P +P+ P
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PPQGDNK 169
Query: 151 ERETQYQKDFRAWPLPRRGDHPWIPKP----VQISAASQASAPILGAPKRRPQSQERWPV 206
R ++ P P+ G+ P P P Q + P P +PQ P
Sbjct: 170 SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP---PP 226
Query: 207 QAAAEAREQEAAPGGAGG 224
Q +++ + PG G
Sbjct: 227 QGDNKSQSARSPPGKPQG 244
Score = 35.8 bits (81), Expect = 0.16
Identities = 49/205 (23%), Positives = 67/205 (32%), Gaps = 20/205 (9%)
Query: 34 SEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQG-----ELDAVARATGPAP- 87
S + P PQ PPPQ QP PP + P QG + GP P
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQ 165
Query: 88 GPTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQD----YRAWKVQRPEPSCRPRSEY 143
G R + PG+ P G GP + K Q P P +P+
Sbjct: 166 GDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP- 224
Query: 144 QPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP----VQISAASQASAPILGAPKRRPQ 199
P + + P P+ G+ P P P Q + P P +PQ
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 284
Query: 200 SQERWPVQAAAEAREQEAAPGGAGG 224
P Q +++R + PG G
Sbjct: 285 GP---PPQGGSKSRSSRSPPGKPQG 306
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 78.6 bits (192), Expect = 2e-14
Identities = 170/721 (23%), Positives = 244/721 (33%), Gaps = 146/721 (20%)
Query: 36 ATEHPG--APPQPP----PPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPA--- 86
++E PG A QPP P QQ PA PP+ + + Q L + A+A GP
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPA-KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 87 ---PGPTGEREPAAGPGRSGP---GPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPR 140
PGP AGPG++ GP GPA +Q A +P P +P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA----KPPPQ-QPG 495
Query: 141 SEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQS 200
S PS P + Q+ A P P++ P KP S +P +
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQ---PGSTKPPSQQPGSA-----------KPSA 541
Query: 201 QERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP 260
Q+ P + +A+ + + G+G K K P+ +GL P
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVSPSAKQPPS------QGLPKTICP 590
Query: 261 LPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIK-------- 312
L ++ PE + + + + E + W +
Sbjct: 591 L-CNTTELLLHVPEKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 313 -PVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEP 371
+ P+ + PQ P K T+ SA K T+ K ++ S EP K P
Sbjct: 648 GDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 372 PKVEKPSVQSS------KPKKTSASHKPTR-------KAKDKQAVSGQAAKKKSAEGPST 418
P V++P++ S +P + + KP +DK V+ K+ P+T
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 419 ---------TKPD---DKEQSKEMNN-----KLAEAKES-----------------LAQP 444
TKPD K QS+ K AK S + +P
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 445 VSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPV 504
SDS P + K Q V P K + Q + + P P P P P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884
Query: 505 KDQDHTVPEPLKNESPVI-SAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
Q TVP P ++ P S S+ PK+Q P P + V L G
Sbjct: 885 AGQ--TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ-PTTPQET------VTGKLFGFG 935
Query: 564 PRIPEPVKNQAPMV--PAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIV 621
I N P P GP PM AP Q P P K G
Sbjct: 936 ASIFSQASNLISTAGQPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Query: 622 PAPVKDEGPMVSAPIKDQ---------DPMVPEHP---KDESAMATAPIKNQGSMVSEPV 669
PAP K S P+K + +P + P + E+ PIK+ S+ +EP
Sbjct: 988 PAPAK------SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
Query: 670 K 670
K
Sbjct: 1042 K 1042
Score = 70.1 bits (170), Expect = 8e-12
Identities = 154/656 (23%), Positives = 231/656 (35%), Gaps = 133/656 (20%)
Query: 217 AAPGGAGG--------LAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQA-- 266
AA GGA G + AG + + + A ++ RA+GL P AA++
Sbjct: 21 AAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS 80
Query: 267 -----QVQATGP--EAGR----GRAAADALNRQIREEV--------ASAVSSSYRNEFRA 307
++ ++ P ++GR GR A L++ + + S+ E ++
Sbjct: 81 MHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
Query: 308 WTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFK-------GEASKP-TTADNKVIDRRR 359
TD+K P + + + +S +F EAS+ TT KV+ + +
Sbjct: 141 RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ 200
Query: 360 IRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTT 419
+ E +PP ++P PK+ P ++ +++S Q +K ++ P T
Sbjct: 201 GKP---EGIIKPPLQQQPP--KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTG 255
Query: 420 KPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQ 479
KP Q + AK L + S Q + SV P L P +Q
Sbjct: 256 KP---IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE-----SVKPSLPSPSKPPIQ 307
Query: 480 EPLK-KQGSVVPGPPKDL-GPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPP 537
+P K + PG K GP P Q + +PL + + PV Q P PP
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKP---PAQPSGLTKPLAQQPGTVKPPV--QPPGTTKPP 362
Query: 538 KNQSPMVPAK--VKDQGSVVPESLKDQGPRIPEPVKNQAPMV-PAPVKDEGPMVSASVKD 594
P+ PAK + GS P S + GP+ Q P V P + GP + +
Sbjct: 363 --AQPLGPAKPPAQQTGSEKPSS-EQPGPK----ALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 595 QGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMA 654
P A Q P + +P K GP PV+ GP + P P SA
Sbjct: 416 GTPKPLA----QQPGLQSPAKAPGP-TKTPVQQPGP-------GKIPAQQAGPGKTSAQQ 463
Query: 655 TAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVK 714
T P K + GP K P + GP P
Sbjct: 464 TGPTKPPSQL------------PGPAK------------------PPPQQPGPAKPPP-- 491
Query: 715 NQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLK-------NQVPIVPVPLKDQDPLVPVP 767
Q P Q + PP+ G P P + +Q P P Q P P
Sbjct: 492 -QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ----PSP 546
Query: 768 AKDQGPAVPEPLKTQGPRDP-QLPTVSP---------LPRVMIPTAPHTEYIESSP 813
AK +P+ G P Q PTVSP LP+ + P TE + P
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Score = 67.0 bits (162), Expect = 7e-11
Identities = 185/834 (22%), Positives = 285/834 (34%), Gaps = 156/834 (18%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQ------------GELDAVARATGPAP 87
PG PP P +++QP A P A+ + AQ G A+ GPA
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Query: 88 GP---TGEREPAA---GPGRSGPGPGLGS--GSTSGPADSVMRQDYRAWKVQRPEPSCRP 139
P TG +P++ GP PG+G GPA +Q V P+P +
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ------VGTPKPLAQQ 424
Query: 140 RSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQ 199
P+ AP +T Q+ P P + P Q + + SA G K P
Sbjct: 425 PGLQSPAKAPGPTKTPVQQ-----PGPGK-------IPAQQAGPGKTSAQQTGPTK--PP 470
Query: 200 SQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQT 259
SQ P A+ Q+ P G A ++ K P Q
Sbjct: 471 SQLPGP----AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP-------------QQ 513
Query: 260 PLPAAQAQVQ--ATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPI 317
P PA + Q +T P + + +A + + + ++ S+ ++ + KP++P
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG---KPLQPP 570
Query: 318 KAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKP 377
P K P + + +T P +++ ++ ++ + V
Sbjct: 571 TVSPSAKQPPSQGLPKTIC----------PLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 378 SVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEA 437
+ P T + K+A+ G A P + P K ++ + A +
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLA-------PVPSSPQPKLKTAPVTTTSAVS 673
Query: 438 KESLAQPVSDSSKTQGP-----VATEPDKDQGSVVPGLLKGQ-GPMVQEPLKKQGSVVPG 491
K S + K P A EP K V L G ++P + P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 492 PPKDLGPMIP-----LPVKDQDHTVPEPLKNESPVI---SAPVKDQGPSVPVPPKNQSPM 543
PPK+ P +P PV D P+ +K + ++ SA K PS V + +
Sbjct: 734 PPKE--PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT 791
Query: 544 VPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDE------GPMVSASVKDQGP 597
P +K + +S G ++ P ++A +P P D GP + + Q
Sbjct: 792 TP-PLKTDSAKPSQSFPPTGEKV-SPFDSKA--IPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 598 MV---SAPVKDQGPIVP----APVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDE 650
V P K Q + P P+ P P P G V P Q P E +
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP--QQSPKPQEQSRRF 905
Query: 651 SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPE----HAKVHDSAVVAPVKNQG 706
S N GS+ P S P Q+ V + A + A + G
Sbjct: 906 SL-------NLGSITDAP-------KSQPTTPQETVTGKLFGFGASIFSQASNL-ISTAG 950
Query: 707 PVVPESVKNQD-PILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVP 765
P S P+ Q PT PPK+ G+ P P K+ +PV + + P
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS----IPVKKETKAPAAE 1006
Query: 766 --VPAKDQGPAV--------PEPLK-----TQGPRDPQLPT---VSPLPRVMIP 801
P +Q P V P P+K T P+ LPT SP P P
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 64.3 bits (155), Expect = 4e-10
Identities = 173/794 (21%), Positives = 260/794 (32%), Gaps = 155/794 (19%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG------PTGERE 94
G P Q P Q A P A +T+ A + + P+P PT +
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP 314
Query: 95 PAAGPG--RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFER 152
PA PG +S PGP SG + +Q +P + +P ++ P +
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 153 ETQYQKDFRAWPLPRR-GDHPWIPK-PVQISAASQASAPILGAPKRRPQSQE---RWPVQ 207
+T +K P P+ P + K P Q ++ +G PK P +Q+ + P +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK--PLAQQPGLQSPAK 432
Query: 208 AAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPA-AQA 266
A + P G G + A ++AGP + G + LP A+
Sbjct: 433 APGPTKTPVQQP-GPGKIPA------------QQAGPGKTSAQQTGPTKPPSQLPGPAKP 479
Query: 267 QVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPP 326
Q GP + A KP +P P
Sbjct: 480 PPQQPGPAKPPPQQPGSA------------------------------KPPSQQPGSTKP 509
Query: 327 DDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSV-QSSKPK 385
+ S Q G P+ ++P + P KPS QS+KP
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGS-----------AKPSAQQPSPAKPSAQQSTKPV 558
Query: 386 KTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPV 445
+ S KP + VS A + S P T P L E L +
Sbjct: 559 SQTGSGKPLQ----PPTVSPSAKQPPSQGLPKTICP------------LCNTTELL---L 599
Query: 446 SDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDL--GPMIPLP 503
K TE S L G P K+ + K G + P+P
Sbjct: 600 HVPEKANFNTCTECQTTVCS-----LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
Q P+ S V + + Q S P K+ +P K
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTS---PKKDAAP-----------------KQDL 694
Query: 564 PRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVP-----APVKGEG 618
+ PEP K P+V P P A + +S P + P VP APV +
Sbjct: 695 SKAPEP-KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 619 PIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESA--MATAPIKNQGSMVSEPVKNQGLVV 676
P P VK +VS+ P +P A T P+K + S+ G V
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 677 SGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPK 736
S P + + P DS +++ + GP K Q + PV K+ +P K
Sbjct: 814 S-PFDSKAIPRP----ASDSKIIS---HPGP--SSESKGQKQVDPVQKKE------EPKK 857
Query: 737 NQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDP------QLP 790
Q ++ P+P P+ P P P G VP P ++ P++ L
Sbjct: 858 AQTKMSPKPDAK-------PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 791 TVSPLPRVMIPTAP 804
+++ P+ PT P
Sbjct: 911 SITDAPKSQ-PTTP 923
Score = 40.0 bits (92), Expect = 0.009
Identities = 115/540 (21%), Positives = 187/540 (34%), Gaps = 78/540 (14%)
Query: 42 APPQPP----PPQQQAQPALAPPSARAVAIETQ-PAQGELDAVARATGPAPGPTGEREPA 96
AP QPP PP+ Q AP + V ET+ PA +L+ A E++P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP- 1027
Query: 97 AGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPE---PSCRPRSEYQPSDAP---- 149
P T+ P +V+ K +PE P C+ D P
Sbjct: 1028 -------PPIKDSKSLTAEPQKAVLPTKLE--KSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 150 -FERETQYQKDFRAWPLPRRGD-HPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQ 207
E + Q P P + W+ Q A + P + P+
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 208 AAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQ 267
E+ Q+ A L + E++ + +A + + E L E+ P P
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQ-----EQEVKTEAEKVILEKVKETLSMEKIP-PMVTTD 1192
Query: 268 VQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD 327
+ + + +A+A + + EE E + ++ K KP+ + + P D
Sbjct: 1193 QKQEESKLEKDKASALQEKKPLPEE-----KKLIPEEEKIRSEEK--KPLLEEKKPTPED 1245
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKT 387
K++ E SA E K ++V + E K +V +VQ K +T
Sbjct: 1246 KKLLPEAKTSAP---EEQKHDLLKSQV-------QIAEE--KLEGRVAPKTVQEGKQPQT 1293
Query: 388 SASHKPTRKAKDKQAVSGQAAK--KKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPV 445
P+ + + K K+ + P T KPD E KE K
Sbjct: 1294 KMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEK--------EDDK 1345
Query: 446 SDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVK 505
SD+S +Q P + + D G G+ G + S++P KD+ +
Sbjct: 1346 SDTSSSQQPKSPQGLSDTGYSSDGISSSLGEI--------PSLIPTDEKDILKGLKKDSF 1397
Query: 506 DQDHTVPEP---LKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQ 562
Q+ + P K ES V+S + + S K++ P +V PE KDQ
Sbjct: 1398 SQESSPSSPSDLAKLESTVLS--ILEAQASTLADEKSEKKTQPHEVS------PEQPKDQ 1449
Score = 32.7 bits (73), Expect = 1.4
Identities = 67/286 (23%), Positives = 97/286 (33%), Gaps = 44/286 (15%)
Query: 372 PKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMN 431
PK E P + + P +KAK K++ G + KE+
Sbjct: 2279 PKPEGPVADTVSTDLLISEKDPVKKAK-----------KETGNGIILEVLEAYRDKKELE 2327
Query: 432 NKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVV---PGLLKGQGPMVQEPLKKQGSV 488
+ K SL++ V D + V P K+Q S G GQ +K S
Sbjct: 2328 AE--RTKSSLSETVFDHPPSS--VIALPMKEQLSTTYFTSGETFGQ--------EKPASQ 2375
Query: 489 VP-GPPKDLGPMIPLPVKDQDHTVPEPLKNESPV-ISAPVKDQGPSVPVPPKNQSPMVPA 546
+P G P + LP K P P S + ISA P P PP P P
Sbjct: 2376 LPSGSPS----VSSLPAK------PRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 547 KVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQG-PMVSAPVKD 605
+ S P L + + PV P+ A E +A ++ G P+
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE---TTAVLRSNGLPVTRICTTA 2482
Query: 606 QGPIVPAPVKGEGPIV--PAPVKDEGPMVSAPIKDQDPMVPEHPKD 649
P+ P P +V P + P+ P+ Q P + P D
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 78.6 bits (192), Expect = 2e-14
Identities = 170/721 (23%), Positives = 244/721 (33%), Gaps = 146/721 (20%)
Query: 36 ATEHPG--APPQPP----PPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPA--- 86
++E PG A QPP P QQ PA PP+ + + Q L + A+A GP
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPA-KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 87 ---PGPTGEREPAAGPGRSGP---GPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPR 140
PGP AGPG++ GP GPA +Q A +P P +P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA----KPPPQ-QPG 495
Query: 141 SEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQS 200
S PS P + Q+ A P P++ P KP S +P +
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQ---PGSTKPPSQQPGSA-----------KPSA 541
Query: 201 QERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP 260
Q+ P + +A+ + + G+G K K P+ +GL P
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSG-----KPLQPPTVSPSAKQPPS------QGLPKTICP 590
Query: 261 LPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIK-------- 312
L ++ PE + + + + E + W +
Sbjct: 591 L-CNTTELLLHVPEKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 313 -PVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEP 371
+ P+ + PQ P K T+ SA K T+ K ++ S EP K P
Sbjct: 648 GDLAPVPSSPQ---PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 372 PKVEKPSVQSS------KPKKTSASHKPTR-------KAKDKQAVSGQAAKKKSAEGPST 418
P V++P++ S +P + + KP +DK V+ K+ P+T
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 419 ---------TKPD---DKEQSKEMNN-----KLAEAKES-----------------LAQP 444
TKPD K QS+ K AK S + +P
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 445 VSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPV 504
SDS P + K Q V P K + Q + + P P P P P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884
Query: 505 KDQDHTVPEPLKNESPVI-SAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
Q TVP P ++ P S S+ PK+Q P P + V L G
Sbjct: 885 AGQ--TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ-PTTPQET------VTGKLFGFG 935
Query: 564 PRIPEPVKNQAPMV--PAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIV 621
I N P P GP PM AP Q P P K G
Sbjct: 936 ASIFSQASNLISTAGQPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Query: 622 PAPVKDEGPMVSAPIKDQ---------DPMVPEHP---KDESAMATAPIKNQGSMVSEPV 669
PAP K S P+K + +P + P + E+ PIK+ S+ +EP
Sbjct: 988 PAPAK------SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
Query: 670 K 670
K
Sbjct: 1042 K 1042
Score = 70.1 bits (170), Expect = 8e-12
Identities = 154/656 (23%), Positives = 231/656 (35%), Gaps = 133/656 (20%)
Query: 217 AAPGGAGG--------LAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQA-- 266
AA GGA G + AG + + + A ++ RA+GL P AA++
Sbjct: 21 AAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS 80
Query: 267 -----QVQATGP--EAGR----GRAAADALNRQIREEV--------ASAVSSSYRNEFRA 307
++ ++ P ++GR GR A L++ + + S+ E ++
Sbjct: 81 MHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
Query: 308 WTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFK-------GEASKP-TTADNKVIDRRR 359
TD+K P + + + +S +F EAS+ TT KV+ + +
Sbjct: 141 RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ 200
Query: 360 IRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTT 419
+ E +PP ++P PK+ P ++ +++S Q +K ++ P T
Sbjct: 201 GKP---EGIIKPPLQQQPP--KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTG 255
Query: 420 KPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQ 479
KP Q + AK L + S Q + SV P L P +Q
Sbjct: 256 KP---IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE-----SVKPSLPSPSKPPIQ 307
Query: 480 EPLK-KQGSVVPGPPKDL-GPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPP 537
+P K + PG K GP P Q + +PL + + PV Q P PP
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKP---PAQPSGLTKPLAQQPGTVKPPV--QPPGTTKPP 362
Query: 538 KNQSPMVPAK--VKDQGSVVPESLKDQGPRIPEPVKNQAPMV-PAPVKDEGPMVSASVKD 594
P+ PAK + GS P S + GP+ Q P V P + GP + +
Sbjct: 363 --AQPLGPAKPPAQQTGSEKPSS-EQPGPK----ALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 595 QGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMA 654
P A Q P + +P K GP PV+ GP + P P SA
Sbjct: 416 GTPKPLA----QQPGLQSPAKAPGP-TKTPVQQPGP-------GKIPAQQAGPGKTSAQQ 463
Query: 655 TAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVK 714
T P K + GP K P + GP P
Sbjct: 464 TGPTKPPSQL------------PGPAK------------------PPPQQPGPAKPPP-- 491
Query: 715 NQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLK-------NQVPIVPVPLKDQDPLVPVP 767
Q P Q + PP+ G P P + +Q P P Q P P
Sbjct: 492 -QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ----PSP 546
Query: 768 AKDQGPAVPEPLKTQGPRDP-QLPTVSP---------LPRVMIPTAPHTEYIESSP 813
AK +P+ G P Q PTVSP LP+ + P TE + P
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Score = 67.0 bits (162), Expect = 7e-11
Identities = 185/834 (22%), Positives = 285/834 (34%), Gaps = 156/834 (18%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQ------------GELDAVARATGPAP 87
PG PP P +++QP A P A+ + AQ G A+ GPA
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Query: 88 GP---TGEREPAA---GPGRSGPGPGLGS--GSTSGPADSVMRQDYRAWKVQRPEPSCRP 139
P TG +P++ GP PG+G GPA +Q V P+P +
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ------VGTPKPLAQQ 424
Query: 140 RSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQ 199
P+ AP +T Q+ P P + P Q + + SA G K P
Sbjct: 425 PGLQSPAKAPGPTKTPVQQ-----PGPGK-------IPAQQAGPGKTSAQQTGPTK--PP 470
Query: 200 SQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQT 259
SQ P A+ Q+ P G A ++ K P Q
Sbjct: 471 SQLPGP----AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP-------------QQ 513
Query: 260 PLPAAQAQVQ--ATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPI 317
P PA + Q +T P + + +A + + + ++ S+ ++ + KP++P
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG---KPLQPP 570
Query: 318 KAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKP 377
P K P + + +T P +++ ++ ++ + V
Sbjct: 571 TVSPSAKQPPSQGLPKTIC----------PLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 378 SVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEA 437
+ P T + K+A+ G A P + P K ++ + A +
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLA-------PVPSSPQPKLKTAPVTTTSAVS 673
Query: 438 KESLAQPVSDSSKTQGP-----VATEPDKDQGSVVPGLLKGQ-GPMVQEPLKKQGSVVPG 491
K S + K P A EP K V L G ++P + P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 492 PPKDLGPMIP-----LPVKDQDHTVPEPLKNESPVI---SAPVKDQGPSVPVPPKNQSPM 543
PPK+ P +P PV D P+ +K + ++ SA K PS V + +
Sbjct: 734 PPKE--PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT 791
Query: 544 VPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDE------GPMVSASVKDQGP 597
P +K + +S G ++ P ++A +P P D GP + + Q
Sbjct: 792 TP-PLKTDSAKPSQSFPPTGEKV-SPFDSKA--IPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 598 MV---SAPVKDQGPIVP----APVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDE 650
V P K Q + P P+ P P P G V P Q P E +
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP--QQSPKPQEQSRRF 905
Query: 651 SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPE----HAKVHDSAVVAPVKNQG 706
S N GS+ P S P Q+ V + A + A + G
Sbjct: 906 SL-------NLGSITDAP-------KSQPTTPQETVTGKLFGFGASIFSQASNL-ISTAG 950
Query: 707 PVVPESVKNQD-PILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVP 765
P S P+ Q PT PPK+ G+ P P K+ +PV + + P
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS----IPVKKETKAPAAE 1006
Query: 766 --VPAKDQGPAV--------PEPLK-----TQGPRDPQLPT---VSPLPRVMIP 801
P +Q P V P P+K T P+ LPT SP P P
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 64.3 bits (155), Expect = 4e-10
Identities = 173/794 (21%), Positives = 260/794 (32%), Gaps = 155/794 (19%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPG------PTGERE 94
G P Q P Q A P A +T+ A + + P+P PT +
Sbjct: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP 314
Query: 95 PAAGPG--RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFER 152
PA PG +S PGP SG + +Q +P + +P ++ P +
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 153 ETQYQKDFRAWPLPRR-GDHPWIPK-PVQISAASQASAPILGAPKRRPQSQE---RWPVQ 207
+T +K P P+ P + K P Q ++ +G PK P +Q+ + P +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK--PLAQQPGLQSPAK 432
Query: 208 AAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPA-AQA 266
A + P G G + A ++AGP + G + LP A+
Sbjct: 433 APGPTKTPVQQP-GPGKIPA------------QQAGPGKTSAQQTGPTKPPSQLPGPAKP 479
Query: 267 QVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPP 326
Q GP + A KP +P P
Sbjct: 480 PPQQPGPAKPPPQQPGSA------------------------------KPPSQQPGSTKP 509
Query: 327 DDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSV-QSSKPK 385
+ S Q G P+ ++P + P KPS QS+KP
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGS-----------AKPSAQQPSPAKPSAQQSTKPV 558
Query: 386 KTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPV 445
+ S KP + VS A + S P T P L E L +
Sbjct: 559 SQTGSGKPLQ----PPTVSPSAKQPPSQGLPKTICP------------LCNTTELL---L 599
Query: 446 SDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDL--GPMIPLP 503
K TE S L G P K+ + K G + P+P
Sbjct: 600 HVPEKANFNTCTECQTTVCS-----LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654
Query: 504 VKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQG 563
Q P+ S V + + Q S P K+ +P K
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTS---PKKDAAP-----------------KQDL 694
Query: 564 PRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVP-----APVKGEG 618
+ PEP K P+V P P A + +S P + P VP APV +
Sbjct: 695 SKAPEP-KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 619 PIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESA--MATAPIKNQGSMVSEPVKNQGLVV 676
P P VK +VS+ P +P A T P+K + S+ G V
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 677 SGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPK 736
S P + + P DS +++ + GP K Q + PV K+ +P K
Sbjct: 814 S-PFDSKAIPRP----ASDSKIIS---HPGP--SSESKGQKQVDPVQKKE------EPKK 857
Query: 737 NQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDP------QLP 790
Q ++ P+P P+ P P P G VP P ++ P++ L
Sbjct: 858 AQTKMSPKPDAK-------PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 791 TVSPLPRVMIPTAP 804
+++ P+ PT P
Sbjct: 911 SITDAPKSQ-PTTP 923
Score = 40.0 bits (92), Expect = 0.009
Identities = 115/540 (21%), Positives = 187/540 (34%), Gaps = 78/540 (14%)
Query: 42 APPQPP----PPQQQAQPALAPPSARAVAIETQ-PAQGELDAVARATGPAPGPTGEREPA 96
AP QPP PP+ Q AP + V ET+ PA +L+ A E++P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP- 1027
Query: 97 AGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPE---PSCRPRSEYQPSDAP---- 149
P T+ P +V+ K +PE P C+ D P
Sbjct: 1028 -------PPIKDSKSLTAEPQKAVLPTKLE--KSPKPESTCPLCKTELNIGSKDPPNFNT 1078
Query: 150 -FERETQYQKDFRAWPLPRRGD-HPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQ 207
E + Q P P + W+ Q A + P + P+
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
Query: 208 AAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQ 267
E+ Q+ A L + E++ + +A + + E L E+ P P
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQ-----EQEVKTEAEKVILEKVKETLSMEKIP-PMVTTD 1192
Query: 268 VQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD 327
+ + + +A+A + + EE E + ++ K KP+ + + P D
Sbjct: 1193 QKQEESKLEKDKASALQEKKPLPEE-----KKLIPEEEKIRSEEK--KPLLEEKKPTPED 1245
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKT 387
K++ E SA E K ++V + E K +V +VQ K +T
Sbjct: 1246 KKLLPEAKTSAP---EEQKHDLLKSQV-------QIAEE--KLEGRVAPKTVQEGKQPQT 1293
Query: 388 SASHKPTRKAKDKQAVSGQAAK--KKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPV 445
P+ + + K K+ + P T KPD E KE K
Sbjct: 1294 KMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEK--------EDDK 1345
Query: 446 SDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVK 505
SD+S +Q P + + D G G+ G + S++P KD+ +
Sbjct: 1346 SDTSSSQQPKSPQGLSDTGYSSDGISSSLGEI--------PSLIPTDEKDILKGLKKDSF 1397
Query: 506 DQDHTVPEP---LKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQ 562
Q+ + P K ES V+S + + S K++ P +V PE KDQ
Sbjct: 1398 SQESSPSSPSDLAKLESTVLS--ILEAQASTLADEKSEKKTQPHEVS------PEQPKDQ 1449
Score = 32.7 bits (73), Expect = 1.4
Identities = 67/286 (23%), Positives = 97/286 (33%), Gaps = 44/286 (15%)
Query: 372 PKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMN 431
PK E P + + P +KAK K++ G + KE+
Sbjct: 2279 PKPEGPVADTVSTDLLISEKDPVKKAK-----------KETGNGIILEVLEAYRDKKELE 2327
Query: 432 NKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVV---PGLLKGQGPMVQEPLKKQGSV 488
+ K SL++ V D + V P K+Q S G GQ +K S
Sbjct: 2328 AE--RTKSSLSETVFDHPPSS--VIALPMKEQLSTTYFTSGETFGQ--------EKPASQ 2375
Query: 489 VP-GPPKDLGPMIPLPVKDQDHTVPEPLKNESPV-ISAPVKDQGPSVPVPPKNQSPMVPA 546
+P G P + LP K P P S + ISA P P PP P P
Sbjct: 2376 LPSGSPS----VSSLPAK------PRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 547 KVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQG-PMVSAPVKD 605
+ S P L + + PV P+ A E +A ++ G P+
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE---TTAVLRSNGLPVTRICTTA 2482
Query: 606 QGPIVPAPVKGEGPIV--PAPVKDEGPMVSAPIKDQDPMVPEHPKD 649
P+ P P +V P + P+ P+ Q P + P D
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 77.8 bits (190), Expect = 4e-14
Identities = 185/856 (21%), Positives = 281/856 (32%), Gaps = 123/856 (14%)
Query: 37 TEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGP------- 89
T P P+PPPP PA A A+ +P + AT P P
Sbjct: 26 TPRPPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 90 --TGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSD 147
T R PA+ P SG G + P + RA RP P + +
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGP--VSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 148 APFE-RETQYQKDFRAWPLPRR---GDHPWIPKPVQISAASQASAPILGAPKRRPQSQER 203
+ T+ K RR G P P P ++ S+A+ +G P+ P ++ R
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPR 199
Query: 204 WP-------VQAAAEAREQEAAPG-----GAGGLAAGKASGADERDTRRKAGPAWIVRRA 251
P V +A+E E +P AGG AS + + PA A
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 252 EGLGHEQTP-LPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAV----SSSYRNEFR 306
G TP PA +Q + G +A R R++ A A+ SS
Sbjct: 260 RG-----TPRAPAHPSQPKPKGLQALRPPQVTPP-----RKDAAPALGPLSSSPLATPSP 309
Query: 307 AWTDIKPVKP-----------IKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVI 355
+ T +PV P + P P S + S P T ++
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 356 DRRRIRSLYSEPFKEPPKVE------------KPSVQS-------SKPKKTSASHKPTRK 396
S+ + P + PP ++ PS+Q+ S + T++ PT +
Sbjct: 370 P-----SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 397 AKDK---QAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQG 453
A + A S P++T PD ++ + ++ P S
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA--VSPLSS 482
Query: 454 PVATEPDKDQGSVVPGLLKGQGP---MVQEPLKKQGSVVP----GPPKDLGPMIPLPVKD 506
P+ P + S+ Q P ++ PL+ Q S+ P PP L P+++
Sbjct: 483 PLTIHPLQALSSLASH--SPQAPLSSLIMPPLETQSSLAPPSLQTPPASL---TTPPLEN 537
Query: 507 QDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRI 566
P PL+ S ++ P + P P P Q+P P+ + P S+ P+
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLET-PPCPAPCPLQAP--PSPLTTPPPETPSSIATPPPQA 594
Query: 567 PEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPA-----PVKGEGPIV 621
P P P+ P P+ + P ++ P P PA P+ P
Sbjct: 595 P-PALASPPLQGLPSPPLSPLATPP-PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 622 PAPVKDE------GPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLV 675
P + P S P+ Q P P S AT P + S+ + P++
Sbjct: 653 PNALAVHLLQAPFSPPPSPPV--QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 676 VSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPP 735
+ P P A +A V P P + P V P + PP
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 736 KNQGRIVPEPLKNQVPIVP----VPLKDQDPLVPVPAKDQGPAVPE---PLKTQGPRDPQ 788
+ PL P P P P P Q P P P+ PQ
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Query: 789 LPTVSPLPRVMIPTAP 804
P V P + +P +P
Sbjct: 831 APPVLAAPLLQVPPSP 846
Score = 57.8 bits (138), Expect = 4e-08
Identities = 139/648 (21%), Positives = 212/648 (32%), Gaps = 76/648 (11%)
Query: 186 ASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAG----GLAAGKASGADERDTRRK 241
A AP L P RP R P A A G G AG GA ++ +
Sbjct: 19 ARAPGLLTP--RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 242 AGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSY 301
AGP R+ G PA++ P +GRG A A N VSS
Sbjct: 77 AGPT----RSAGTSSRN---PASRP------PASGRGERAPPAKNTS-----PGPVSSPG 118
Query: 302 RNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKG---EASKPTTADNKVIDRR 358
R K ++ + K SA G + S PT R
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
Query: 359 RIRSLYSE---PFKEPPKVEKPSVQSSKPKKTSASH----KPTRKAKDKQAVSGQAAKKK 411
R R+ +E P P +P + + +SAS +P+ A+ + + G +
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 412 SAEGPSTTKP-DDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGL 470
S S+ P +S A +QP + P P + + G
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 471 LKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG 530
L P + VP P P+ P PL SP SAP Q
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP--SAPPSLQ- 355
Query: 531 PSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSA 590
++P PP P + P SL+ P I P +P + AP P+ +
Sbjct: 356 -TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP-IQVPHSLTSPSLQAP---PSPLALS 410
Query: 591 SVKDQGPMVSAPVKDQGPIV---PAPVKGE--GPIVPAPVKDEGPMVSAPIKDQDPMVPE 645
S++ + S ++ + P + P PA + P + AP+ +P
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS-----LPA 465
Query: 646 HPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQ 705
P +++++ A S +S P+ L + P S ++ P++ Q
Sbjct: 466 SPPLQTSLSPAV-----SPLSSPLTIHPLQALSSLASHSPQAPL-----SSLIMPPLETQ 515
Query: 706 GPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVP 765
+ P S++ L P +N + P PL+ + P + P P
Sbjct: 516 SSLAPPSLQTPPASLTT----------PPLENLPSLAPPPLQTASAPLTTPHLETPPC-P 564
Query: 766 VPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP 813
P Q P P PL T P P P +P + + S P
Sbjct: 565 APCPLQAP--PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Score = 35.4 bits (80), Expect = 0.21
Identities = 69/342 (20%), Positives = 106/342 (30%), Gaps = 65/342 (19%)
Query: 519 SPVISAP--VKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQ-----GPRIPEPVK 571
+P AP + + P P PP +P + G+V + L ++ G IPE
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 572 NQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGP-IVPAPVKGEGPIVPAPVKDEGP 630
P A P +G + P K+ P V +P + G P P+ +G
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGER-APPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 631 MVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVP-- 688
+SA E PK + A A G P + + +V +P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP--SPAMARRSRAAGTEVGLPRP 192
Query: 689 -----------------EHAKVHDSAVVAPVKNQGPVVPESVKN---------------- 715
A H + +P + P ++
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 716 -----------QDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLV 764
+ P P K +G L+PP+ V P K+ P + PL
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-----VTPPRKDAAPALG-PLSSSPLAT 306
Query: 765 PVPAKDQGPAVPEPLKTQGPRDPQLPTVSPL--PRVMIPTAP 804
P P+ + VP P P LP PL P + P +P
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Score = 33.5 bits (75), Expect = 0.81
Identities = 79/354 (22%), Positives = 113/354 (31%), Gaps = 44/354 (12%)
Query: 313 PVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPP 372
P+ P+ A P + P+ VH A F S P A + + P + PP
Sbjct: 641 PLSPL-ATPSPQAPNALAVH--LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 373 KVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNN 432
+ P +Q S P+ + A + P + P +
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 433 KLAEAKESLAQPVSD-SSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPG 491
A L P S +S P+A P + P L + P P
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQ----APPALATPPLQALPSPPASFPGQAPF 813
Query: 492 PPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQ 551
P PM PL P PV++AP+ PS P P Q+P P
Sbjct: 814 SPSASLPMSPLAT---------PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 552 GSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVP 611
SV GPR+ + AP P P P S S GP + A P
Sbjct: 865 TSV-------SGPRLTLAL---APGPPPP-----PSRSPSSTLSGPDL-AGHSSSATSTP 908
Query: 612 APVKG--EGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGS 663
++G GP EG ++P D + + HP S P+ +G+
Sbjct: 909 EELRGYDSGP--------EGGAAASPPPDAE-LAACHPAAWSRGPAPPLAFRGA 953
Score = 32.3 bits (72), Expect = 1.8
Identities = 54/213 (25%), Positives = 70/213 (32%), Gaps = 26/213 (12%)
Query: 36 ATEHPGAPPQ------PPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGP 89
AT P APP PP A P L P G +A A GP P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP-- 882
Query: 90 TGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQP-SDA 148
P+ P + GP L S+S + + Y + S P +E A
Sbjct: 883 ----PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938
Query: 149 PFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQA 208
+ R FR P PW P A SA L + P
Sbjct: 939 AWSRGPAPPLAFRGAP---GAPLPWPP------ATGPGSADGLCTIYETEGPESATP--- 986
Query: 209 AAEAREQEAAPGGAGG-LAAGKASGADERDTRR 240
A A + +PG +GG AAG +GA R ++
Sbjct: 987 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/83 (25%), Positives = 30/83 (36%), Gaps = 9/83 (10%)
Query: 24 IAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARAT 83
+AV L+ +S P P PP P+ PPS ++ P Q
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ---------V 706
Query: 84 GPAPGPTGEREPAAGPGRSGPGP 106
P+P + P+A P P P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPP 729
Score = 31.2 bits (69), Expect = 4.0
Identities = 39/162 (24%), Positives = 56/162 (34%), Gaps = 13/162 (8%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREP---A 96
P P PP P APP A ++ P+ ++ + P P R P A
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP-----RVPPLLA 762
Query: 97 AGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQY 156
A P + P P + P Q A + P + + P APF
Sbjct: 763 APPLQVPPSP--PASLPMSPLAKPPPQAPPALATPPLQALPSPPASF-PGQAPFSPSASL 819
Query: 157 QKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRP 198
A P P+ P + P+ S ++P L AP+R P
Sbjct: 820 PMSPLATPPPQA--PPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Score = 30.4 bits (67), Expect = 6.9
Identities = 50/197 (25%), Positives = 62/197 (31%), Gaps = 24/197 (12%)
Query: 27 PLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQGELDAVARATG 84
PL T H PP P P QA P+ PP +I T P Q A A+
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA---PPALASP 601
Query: 85 PAPG-PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPE--------- 134
P G P+ P A P P P L P P+
Sbjct: 602 PLQGLPSPPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 135 ---PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPIL 191
P P S P APF A P P + P+Q+ + AS P+
Sbjct: 661 LQAPFSPPPS--PPVQAPFSPPASPPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPM- 716
Query: 192 GAPKRRPQSQERWPVQA 208
+P P Q P+ A
Sbjct: 717 -SPSATPPPQAPPPLAA 732
>gi|13376306 MAP6 domain containing 1 [Homo sapiens]
Length = 199
Score = 76.6 bits (187), Expect = 8e-14
Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 20/156 (12%)
Query: 1 MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEA-TEHPG----APPQPPPPQQQAQP 55
MAWPCI+R CC+AR WNQLD++D+AVPL YS+ +E PG A + PP
Sbjct: 1 MAWPCISRLCCLARRWNQLDRSDVAVPLTLHGYSDLDSEEPGTGGAASRRGQPPAGARDS 60
Query: 56 ALAPPSA---RAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPG----- 107
P R + T PA G D G PG G R ++ + P PG
Sbjct: 61 GRDVPLTQYQRDFGLWTTPA-GPKDP---PPGRGPGAGGRRGKSSAQSSAPPAPGARGVY 116
Query: 108 ---LGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPR 140
+G + + RQ+++AW +P S + +
Sbjct: 117 VLPIGDADAAAAVTTSYRQEFQAWTGVKPSRSTKTK 152
Score = 40.8 bits (94), Expect = 0.005
Identities = 16/30 (53%), Positives = 23/30 (76%)
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKPIKAKP 321
+ A+AV++SYR EF+AWT +KP + K KP
Sbjct: 124 DAAAAVTTSYRQEFQAWTGVKPSRSTKTKP 153
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 75.9 bits (185), Expect = 1e-13
Identities = 122/522 (23%), Positives = 202/522 (38%), Gaps = 62/522 (11%)
Query: 177 PVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADER 236
PV+ A S A A + + ++ + P +A + A+E+ +P A + E+
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA---------KSPEK 569
Query: 237 DTRRKAGPAWIVRRAEGLGHEQTPLPA-AQAQVQATGPEAGRGRAAADALNRQIREEVAS 295
+ + +A+ E+ PA A++ +A P ++ A+A ++EE S
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAKS 628
Query: 296 AVSSSYRNEFRAWTDIKPVKPIKAKPQYK-----------PPDDKMVHETSYSAQFKGEA 344
+ ++ T + P KAK K P + + K EA
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 345 SKPTTADNKVIDR----RRIRSLYSEPFKEPPKVEKPSVQSSK-PKKTSASHKPTRKAKD 399
P A + V + + +S E K P K + P + +K P+K + K K+ +
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 400 KQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAE-AKESLAQPVSDSSKTQGPV--- 455
K A S + AK + P P KE+++ +K E AK + + V K + P+
Sbjct: 749 K-AKSPEKAKTLDVKSPEAKTP-AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 456 ATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPL 515
A P+K+ +P + + P V+E K Q V PPK K ++ P
Sbjct: 807 AKAPEKE----IPKKEEVKSP-VKEEEKPQEVKVKEPPK----------KAEEEKAPATP 851
Query: 516 KNESPVISAPVKDQGPSVPVP-PKNQSPMVPAKVKDQGSVVPESLKDQG---PRIPEPVK 571
K E S K++ P P PK + PA K + S V E+ K++ ++P P K
Sbjct: 852 KTEEKKDSK--KEEAPKKEAPKPKVEEKKEPAVEKPKESKV-EAKKEEAEDKKKVPTPEK 908
Query: 572 NQAPMVPAPVKDEGPMVSASVKDQGP---MVSAPVKDQGPIVPAPVKGEGPIVPAPVKDE 628
+AP +D P V + P P K AP K + A +E
Sbjct: 909 -EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967
Query: 629 GPMVSAPIKDQDPMV---PEHPKDESAMATAPIKNQGSMVSE 667
P A K+ D + P PK E A ++ + S E
Sbjct: 968 KPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 72.4 bits (176), Expect = 2e-12
Identities = 124/564 (21%), Positives = 210/564 (37%), Gaps = 83/564 (14%)
Query: 199 QSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQ 258
Q++E + E E+EA G+ A+ + K+ PA E +
Sbjct: 460 QTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEK--EAK 517
Query: 259 TPLPA-AQAQVQATGPEAGRGRAAADALNRQ-----IREEVASA--VSSSYRNEFRAWTD 310
+P+ A++ +A PE ++ A+ + + +EE S S + E ++ +
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577
Query: 311 IKPVKPIK--AKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDR----------R 358
+K + K AK + K P + E + S K EA P A + V +
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSP-VKEEAKSPAEAKSPVKEEAKSPAEVKSPE 636
Query: 359 RIRSLYSEPFKEPPKVEKPSVQSSK-PKKTSASHKPTRKA--KDKQAVSGQAAKKKSAEG 415
+ +S E K P K + P + +K P+K + K K+ K K V +A + A+
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696
Query: 416 PSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKT----QGPV---ATEPDKDQGSVVP 468
P + E++K + A++ E PV + +KT + PV A P+K +
Sbjct: 697 PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756
Query: 469 GLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPV------- 521
L + P + P K++ P PVK++ V P K +SP+
Sbjct: 757 KTLDVKSPEAKTPAKEEAR---SPADKFPEKAKSPVKEE---VKSPEKAKSPLKEDAKAP 810
Query: 522 ---------ISAPVKD----QGPSVPVPPK----NQSPMVPAKVKDQGSVVPESLKDQGP 564
+ +PVK+ Q V PPK ++P P + + S E+ K + P
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP 870
Query: 565 RIPEPVKNQAPMVPAPVKDEGPMVSASVKDQ----GPMVSAPVK-------------DQG 607
+ P+ + + P V P + + +D+ P AP K +
Sbjct: 871 K-PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929
Query: 608 PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSE 667
P K + P PA K+ P K++ PE A A K S+
Sbjct: 930 KKEPDDAKAKEPSKPAEKKEAAP-EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK 988
Query: 668 PVKNQGLVVSGPVKDQDVVVPEHA 691
P K + S +D PE A
Sbjct: 989 P-KAEKAEKSSSTDQKDSKPPEKA 1011
Score = 58.2 bits (139), Expect = 3e-08
Identities = 97/422 (22%), Positives = 161/422 (38%), Gaps = 56/422 (13%)
Query: 367 PFKEPPKVEK-PSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKE 425
PF P + K PSV + K+ K K+ +K+ V + +++ T+ ++KE
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKS-EKETVIVEEQTEETQVTEEVTEEEEKE 477
Query: 426 QSKEMNNKLAEAKESLAQPVSDSSKTQ-GPVATEPDKDQGSVVPGLLKGQGPMVQEPLKK 484
+E + +E A+ + +K+ A P+K+ S V + + P + +K
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE--EAKSPAEAKSPEK 535
Query: 485 QGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMV 544
+ + P K P K++ + PE E +P + + P P +
Sbjct: 536 EEAKSPAEVKS-PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 545 PAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVK 604
PA+ K PE K PVK +A PA K +PVK
Sbjct: 595 PAEAKS-----PEKAKS-------PVKEEAKS-PAEAK------------------SPVK 623
Query: 605 DQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSM 664
++ PA VK +P K+E +P K + P E E A + P+K +
Sbjct: 624 EEAKS-PAEVKSPEK-AKSPTKEEA---KSPEKAKSPEKEEAKSPEKAKS--PVKAEAK- 675
Query: 665 VSEPVKNQGLVVSGPVKDQDVVVPEHAK--VHDSAVVAPVKNQGPVVPESVKNQDPILPV 722
P K PVK + PE AK V + A +P K + PV E+ + PV
Sbjct: 676 --SPEK-----AKSPVK-AEAKSPEKAKSPVKEEAK-SPEKAKSPVKEEAKSPEKAKSPV 726
Query: 723 LVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQ 782
+ + P + P + PE K+ + +K + P + + PA P K +
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786
Query: 783 GP 784
P
Sbjct: 787 SP 788
Score = 33.5 bits (75), Expect = 0.81
Identities = 80/394 (20%), Positives = 142/394 (36%), Gaps = 69/394 (17%)
Query: 47 PPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGE------------RE 94
P ++ P A +A A + A+ + A A++ A P E +E
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 95 PAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRA-WKVQRPEPSCRPRSEYQPSDAPFERE 153
A P ++ P T A S ++++ ++ K + PE + + + P + E
Sbjct: 715 EAKSPEKA-KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Query: 154 TQYQKDFRAWPLPRRGDHPW-----IPKPVQISAASQASAPILGAPKRR----PQSQERW 204
+ D P + P P+ + A AP PK+ P +E
Sbjct: 774 ARSPAD----KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 205 P----VQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP 260
P V+ + E+E AP A K +++D++++ P ++ P
Sbjct: 830 PQEVKVKEPPKKAEEEKAP------ATPKTE--EKKDSKKEEAPK-----------KEAP 870
Query: 261 LPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAK 320
P + + + + + A + +++V + + + D KP + K +
Sbjct: 871 KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA-KVEVKEDAKPKE--KTE 927
Query: 321 PQYKPPDDKMVHETSYSAQFKGEA-SKPTTADNKVID-----------RRRIRSLYSEPF 368
K PDD E S A+ K A K T + K + ++L EP
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 369 KEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQA 402
K PK EK SS +K S P + +DK A
Sbjct: 988 K--PKAEKAEKSSSTDQKDSKP--PEKATEDKAA 1017
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 73.6 bits (179), Expect = 7e-13
Identities = 111/364 (30%), Positives = 134/364 (36%), Gaps = 67/364 (18%)
Query: 439 ESLAQPVSDS---SKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
E ++Q S S QGP +K QG P K QGP Q K QG PG P+
Sbjct: 21 EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPG-KPQGPPPQGGNKPQGPPPPGKPQG 79
Query: 496 LGPMIPLPVKDQDHTVPEPL-KNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSV 554
P P D+ + P K + P + QGP P P K Q P + QG
Sbjct: 80 -----PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNRPQGPP 133
Query: 555 VPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPV 614
P K QGP P+ K+++P P P K +GP + QGP P K QGP
Sbjct: 134 PPG--KPQGPP-PQGDKSRSPRSP-PGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGK 188
Query: 615 KGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGL 674
K +GP P P K +GP P+ K S+ S P K QG
Sbjct: 189 KPQGP--PPPGKPQGPP------------PQGDKSRSSQ------------SPPGKPQGP 222
Query: 675 VVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGP----- 729
G + Q P P K QGP K Q P P K QGP
Sbjct: 223 PPQGGNQPQGPPPP------------PGKPQGPPPQGGNKPQGP--PPPGKPQGPPAQGG 268
Query: 730 ----TVLQPP-KNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGP 784
+ PP K QG E Q P P Q P P + QGP P P +
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQGGRPS 327
Query: 785 RDPQ 788
R PQ
Sbjct: 328 RPPQ 331
Score = 60.1 bits (144), Expect = 8e-09
Identities = 86/268 (32%), Positives = 100/268 (37%), Gaps = 49/268 (18%)
Query: 527 KDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGP 586
K QGP P P K Q P K QG P K QGP P+ K+++P P P K +GP
Sbjct: 46 KPQGPPPP-PGKPQGPPPQGGNKPQGPPPPG--KPQGPP-PQGDKSRSPRSP-PGKPQGP 100
Query: 587 MVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
+ QGP P K QGP + +GP P P K +GP P+
Sbjct: 101 PPQGGNQPQGPP-PPPGKPQGPPPQGGNRPQGP--PPPGKPQGPP------------PQG 145
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
K S S P K QG G + Q P P K QG
Sbjct: 146 DKSRSPR------------SPPGKPQGPPPQGGNQPQGPPPP------------PGKPQG 181
Query: 707 PVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPV 766
P K Q P P K QGP Q K++ P P K Q P + Q P P
Sbjct: 182 PPPQGGKKPQGP--PPPGKPQGPPP-QGDKSRSSQSP-PGKPQGPPPQGGNQPQGP-PPP 236
Query: 767 PAKDQGPAVPEPLKTQGPRDPQLPTVSP 794
P K QGP K QGP P P P
Sbjct: 237 PGKPQGPPPQGGNKPQGPPPPGKPQGPP 264
Score = 58.2 bits (139), Expect = 3e-08
Identities = 71/258 (27%), Positives = 93/258 (36%), Gaps = 14/258 (5%)
Query: 366 EPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKE 425
+P PP+ +K S P K P + Q K + +P
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133
Query: 426 QSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQ 485
+ + +S + P S K QGP ++ QG P K QGP Q K Q
Sbjct: 134 PPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGKKPQ 191
Query: 486 GSVVPGPPKDLGPMIPLPVKDQDHTVPEPL-KNESPVISAPVKDQGPSVPVPPKNQSPMV 544
G PG P+ P P D+ + P K + P + QGP P P K Q P
Sbjct: 192 GPPPPGKPQG-----PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPP 245
Query: 545 PAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVK 604
K QG P K QGP K+Q+ P P K +GP QGP A
Sbjct: 246 QGGNKPQGPPPPG--KPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGN 302
Query: 605 DQGPIVPAPVKGEGPIVP 622
Q P P + +GP P
Sbjct: 303 PQQPQAPPAGQPQGPPRP 320
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/257 (24%), Positives = 85/257 (33%), Gaps = 31/257 (12%)
Query: 34 SEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQG-----ELDAVARATGPAPG 88
S + P PQ PPPQ QP PP + P QG + GP P
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQ 144
Query: 89 PTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQD----YRAWKVQRPEPSCRPRSEYQ 144
R P + PG+ P G GP + K Q P P +P+
Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG--P 202
Query: 145 PSDAPFERETQYQKDFRAWPLPRRGDHPWIPKP----VQISAASQASAPILGAPKRRPQS 200
P R +Q P P+ G+ P P P Q + P P +PQ
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 262
Query: 201 QERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTP 260
P Q ++++ + P GK G +++ GP A G +
Sbjct: 263 P---PAQGGSKSQSARSPP--------GKPQGPPQQEGNNPQGPP---PPAGGNPQQPQA 308
Query: 261 LPAAQAQVQATGPEAGR 277
PA Q Q P+ GR
Sbjct: 309 PPAGQPQGPPRPPQGGR 325
Score = 45.8 bits (107), Expect = 2e-04
Identities = 64/215 (29%), Positives = 77/215 (35%), Gaps = 38/215 (17%)
Query: 582 KDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDP 641
++E P + A QGP K QGP P P K +GP K +GP P
Sbjct: 25 QEESPSLIAG-NPQGPSPQGGNKPQGP-PPPPGKPQGPPPQGGNKPQGP--------PPP 74
Query: 642 MVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAP 701
P+ P + + +P S P K QG G + Q P P
Sbjct: 75 GKPQGPPPQGDKSRSPR-------SPPGKPQGPPPQGGNQPQGPPPP------------P 115
Query: 702 VKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPE--PLKNQVPIVPVPLKD 759
K QGP + Q P P K QGP PP+ P P K Q P +
Sbjct: 116 GKPQGPPPQGGNRPQGP--PPPGKPQGP----PPQGDKSRSPRSPPGKPQGPPPQGGNQP 169
Query: 760 QDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSP 794
Q P P P K QGP K QGP P P P
Sbjct: 170 QGP-PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
Score = 45.4 bits (106), Expect = 2e-04
Identities = 58/210 (27%), Positives = 71/210 (33%), Gaps = 14/210 (6%)
Query: 371 PPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDK--EQSK 428
PP KP P + S P Q Q + P KP + K
Sbjct: 132 PPPPGKPQ---GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Query: 429 EMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSV 488
+ K P D S++ + P K QG G + QGP P K QG
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSS---QSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPP 244
Query: 489 VPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV 548
G K GP P P K Q K++S S P K QGP Q P PA
Sbjct: 245 PQGGNKPQGP--PPPGKPQGPPAQGGSKSQS-ARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Query: 549 KDQGSVVPESLKDQGPRIPEPVKNQAPMVP 578
Q P + + QGP P P + P P
Sbjct: 302 NPQQPQAPPAGQPQGP--PRPPQGGRPSRP 329
Score = 37.7 bits (86), Expect = 0.043
Identities = 43/188 (22%), Positives = 63/188 (33%), Gaps = 22/188 (11%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGP 99
P PQ PPPQ +P PP + + P QG+ ++ P P + P
Sbjct: 53 PPGKPQGPPPQGGNKPQGPPPPGKP---QGPPPQGD-----KSRSPRSPPGKPQGPPPQG 104
Query: 100 GRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKD 159
G GP G GP + Q P P +P+ P R +
Sbjct: 105 GNQPQGPPPPPGKPQGPPPQ------GGNRPQGPPPPGKPQG--PPPQGDKSRSPRSPPG 156
Query: 160 FRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRR---PQSQERWPVQAAAEAREQE 216
P P+ G+ P P P P G K + P + + P ++R +
Sbjct: 157 KPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213
Query: 217 AAPGGAGG 224
+ PG G
Sbjct: 214 SPPGKPQG 221
Score = 35.4 bits (80), Expect = 0.21
Identities = 35/97 (36%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 701 PVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQ 760
P K QGP P+ K++ P P K QGP + QG P P K Q P + Q
Sbjct: 74 PGKPQGPP-PQGDKSRSPRSPP-GKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGNRPQ 130
Query: 761 DPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPR 797
P P P K QGP P+ K++ PR P P P+
Sbjct: 131 GP--PPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQ 164
Score = 33.5 bits (75), Expect = 0.81
Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 18/128 (14%)
Query: 34 SEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGER 93
S +++ P PQ PPPQ QP PP + P QG + GP P +
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGG----NKPQGPPPPGKPQG 262
Query: 94 EPAAG-----PGRSGPGPGLGSGSTSG-------PADSVMRQDYRAWKVQRPEPSCRPRS 141
PA G RS PG G G P Q +A +P+ RP
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322
Query: 142 EYQPSDAP 149
+PS P
Sbjct: 323 GGRPSRPP 330
Score = 31.2 bits (69), Expect = 4.0
Identities = 34/93 (36%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 705 QGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLV 764
QGP K Q P P K QGP K QG P P K Q P P K + P
Sbjct: 37 QGPSPQGGNKPQGPPPPP-GKPQGPPPQGGNKPQGP--PPPGKPQGP-PPQGDKSRSPRS 92
Query: 765 PVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPR 797
P P K QGP + QGP P P P+
Sbjct: 93 P-PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 124
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 73.2 bits (178), Expect = 9e-13
Identities = 139/613 (22%), Positives = 236/613 (38%), Gaps = 111/613 (18%)
Query: 289 IREEVASAVSSSYRNEFRAWT--DIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASK 346
+ EE S E+ + + + +P + QY+ +++ ++ E K
Sbjct: 9732 LEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEK 9791
Query: 347 PTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSK-----PKKTS-----ASHKPTRK 396
P K + + + +P P KV K +V K PKK +P +
Sbjct: 9792 PIPV--KPVPEEPVPT---KPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKV 9846
Query: 397 AKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVA 456
++K +S +K+ P+ P K + K+ ++ +A PV + P
Sbjct: 9847 FEEKIRISITKREKEQVTEPAAKVPM-KPKRVVAEEKVPVPRKEVAPPVR---VPEVPKE 9902
Query: 457 TEPDKDQGS------VVPGLLKGQGPMV--QEPLKKQGSVVPGPPKDLGPMIPLPVKDQD 508
EP++ V L++ + + +E + VVP P + + PV ++
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEK 9962
Query: 509 HTVPEPLKNESPVISAPVKDQGP--SVPV-------PPKNQSPMVPAKVKDQGSV---VP 556
VP P K E+P P + P VPV PP + P VP K + V VP
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVP 10022
Query: 557 ESLKDQGPRIPE----PVKNQAPMVPAPVKDEGPMVSAS------VKDQGPMVSAPVKDQ 606
+ ++ ++PE PV + VPAP K E P + ++ P K +
Sbjct: 10023 KKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVE 10082
Query: 607 GPIVPAPVKGEGPIVPAPV---KDEGPMVSAPIKDQDPMVPEH----PKDESAM----AT 655
P P K E VP PV ++E + I ++ ++PE P++E +
Sbjct: 10083 APPPKVPKKREP--VPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEV 10140
Query: 656 APIKNQGSMVSEPVKNQGLVVSGP---VKDQDVV------------VPE-HAKVHDSAVV 699
P + + E V + V V +++V+ VPE KV + VV
Sbjct: 10141 LPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVV 10200
Query: 700 APVKNQG-----PVVPESVKNQDPILP----VL-----------------VKDQGPTVLQ 733
P K + P VP+ V+ + ILP VL + ++ P++ +
Sbjct: 10201 IPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEE 10260
Query: 734 PPKNQGRIVPEPLKNQVP--IVPVPLKDQDPLVPVPAKDQGPAVPEPL-KTQGP--RDPQ 788
+ VPE +K VP PVP K + P V K VP P+ K + P + P+
Sbjct: 10261 VEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPE 10320
Query: 789 LPTVSPLPRVMIP 801
+P P +V++P
Sbjct: 10321 VPKKVPEKKVLVP 10333
Score = 67.4 bits (163), Expect = 5e-11
Identities = 118/464 (25%), Positives = 177/464 (38%), Gaps = 70/464 (15%)
Query: 370 EPPKVEKPSVQSSKPKKTSASHKPTRKAK-DKQAVSGQAAKKKSAEGPSTTKPDDKEQSK 428
E PK P + P PT+ + K AV + + P + P+ E+ +
Sbjct: 10611 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPE 10670
Query: 429 E--MNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVV------PGLLKGQGPMVQE 480
E + AE E +P + T P P+K +VV P + + P
Sbjct: 10671 EVALEEPPAEVVEE-PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVV 10729
Query: 481 PLKKQGSVVPGPPKDLGPMIPLPVKD--QDHTVPEPLKNESP------VISAPVKDQGPS 532
P KK VVP P+ +P K+ + V P K E P V PV ++ P+
Sbjct: 10730 PEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789
Query: 533 VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPV-KDEGPMVSAS 591
VPVP + +SP P +V ++ PE + + PE K P PV ++E P V
Sbjct: 10790 VPVPERAESP--PPEVYEE----PEEIAPEEEIAPEEEK------PVPVAEEEEPEVPPP 10837
Query: 592 VKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDES 651
+ P P K VP K E P P + E + +K + P P P E
Sbjct: 10838 AVPEEPKKIIPEKK----VPVIKKPEAP-PPKEPEPEKVIEKPKLKPRPPPPPPAPPKED 10892
Query: 652 A------MATAPIKN--QGSMVSEPVKNQGLVVSGPVKDQDVVVPEH-AKVHDSAVVAPV 702
+ P K + V E V+ L V G K ++PE + + V+ V
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSV 10952
Query: 703 KNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKN-QVPIV-------- 753
+ P E +P L K + P V +PP P+P++ +VP V
Sbjct: 10953 LRKRP--EEEEPKVEP--KKLEKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIP 11002
Query: 754 -PVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLP 796
P + + P +P+PA + P +KT P P V P P
Sbjct: 11003 EPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP-----PPVEPEP 11041
Score = 67.0 bits (162), Expect = 7e-11
Identities = 144/621 (23%), Positives = 226/621 (36%), Gaps = 92/621 (14%)
Query: 194 PKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRR-KAGPAWIVRRAE 252
P+ P S+E P + + +E AP + A ++ +A PA + ++
Sbjct: 10241 PEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKK-- 10298
Query: 253 GLGHEQTPLPAAQAQVQ-ATGPEAGRG-----------RAAADALNRQIREEVASAVSSS 300
+ E+ P+P + + A PE + A A R + EE VS +
Sbjct: 10299 -IPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEE---KVSVA 10354
Query: 301 YRNEFRAWTDIKPVKPIKAKPQYKPPDDKM--VHETSYSAQFKGEASKPTTADNKVIDRR 358
+R E ++ ++ ++A+ + P +++ V E +F ++V +
Sbjct: 10355 FRQEVVVKERLE-LEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEH 10413
Query: 359 RIRSLYS--EPFKEPPKVEKPSVQSSKPKKTSASHK--PTRKAKDKQAVSGQAAKKKSAE 414
R+ ++ E F E +VE + PK S K P +K K K+ A+
Sbjct: 10414 RVEKVHRVIEVF-EAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVV----PRKEPPAK 10468
Query: 415 GPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQ 474
P K K + + E P + + P P+K VP K +
Sbjct: 10469 VPEVPK-------KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP--VPPAKKPE 10519
Query: 475 GPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVP 534
P P K VP PK++ P +PV P P K E P P + P
Sbjct: 10520 AP----PPK-----VPEAPKEVVPEKKVPV-------PPPKKPEVPPTKVP---EVPKAA 10560
Query: 535 VPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKD 594
VP K +P K + VPE+ K+ P P PVK V + K+
Sbjct: 10561 VPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVK-----VPEAPKE 10615
Query: 595 QGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKD----- 649
P P VP P K E P P E P V+ P K +P P+
Sbjct: 10616 VVPEKKVP-------VPPPKKPEVPPTKVP---EVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 650 -ESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPV 708
E A + +V EP V+ P K A V + PVK P
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVK--VPE 10723
Query: 709 VPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPE-----PLKNQVPIVPVPLKDQDPL 763
VP+ V + + V+ K + P+ +VPE P K +VP VP + P+
Sbjct: 10724 VPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV 10783
Query: 764 VPVPAKDQGPAVPEPLKTQGP 784
+ ++ PAVP P + + P
Sbjct: 10784 L-----EEKPAVPVPERAESP 10799
Score = 65.1 bits (157), Expect = 3e-10
Identities = 121/532 (22%), Positives = 199/532 (37%), Gaps = 90/532 (16%)
Query: 313 PVKPIKAKPQYKPPD-----DKMVHETSYSAQFKGEASKPTTADNKV----IDRRRI-RS 362
PV P K KP+ PP ++V E + P T +V + +++ +
Sbjct: 10511 PVPPAK-KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA 10569
Query: 363 LYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKK----KSAEGPST 418
+ +P PP+V + + KK A+ P +K + +A K+ K P
Sbjct: 10570 IPPKPESPPPEVPEAPKEVVPEKKVPAA--PPKKPEVTPVKVPEAPKEVVPEKKVPVPPP 10627
Query: 419 TKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMV 478
KP+ K+A ++ + + + ++ P E ++ P +V
Sbjct: 10628 KKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP-----PAEVV 10682
Query: 479 QEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPK 538
+EP V PPK P+P K V + K E P + P + P VP K
Sbjct: 10683 EEPEPAAPPQVTVPPKK-----PVPEKKAPAVVAK--KPELPPVKVP---EVPKEVVPEK 10732
Query: 539 NQSPMVPAKVKDQGSVVPESLKDQGP---------------RIPE----PVKNQAPMVPA 579
+VP K + + VPE K+ P ++PE PV + P VP
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPV 10792
Query: 580 PVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPV---KGEGPIVPAPVKDEGPMVSAP- 635
P + E P + P AP ++ P PV + E P VP P E P P
Sbjct: 10793 PERAESPPPEVY---EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPE 10849
Query: 636 -----IKDQDPMVPEHPKDESAMATAPIKNQG-----SMVSEPVKNQGLVVSGPVKDQDV 685
IK + P+ P+ E + +K + + E VK + + K +
Sbjct: 10850 KKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK-- 10907
Query: 686 VVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEP 745
VPE +V + + P+K VP K +LP + P+ + +V +
Sbjct: 10908 -VPEKPQVPEKVELTPLK-----VPGGEKKVRKLLPE----------RKPEPKEEVVLKS 10951
Query: 746 LKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPR 797
+ + P P + L V + PAVPEP + + ++PTV+ R
Sbjct: 10952 VLRKRPEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRER 10999
Score = 61.2 bits (147), Expect = 4e-09
Identities = 90/325 (27%), Positives = 135/325 (41%), Gaps = 65/325 (20%)
Query: 505 KDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSV-------VPE 557
++ + + EP E P+ PV P PVP K ++P PAKV + +P+
Sbjct: 9780 EEHEEYITEP---EKPIPVKPV----PEEPVPTKPKAP--PAKVLKKAVPEEKVPVPIPK 9830
Query: 558 SLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGE 617
LK P++PE P V +E +S + +++ + K P+ P V E
Sbjct: 9831 KLKPPPPKVPEE--------PKKVFEEKIRISITKREKEQVTEPAAKV--PMKPKRVVAE 9880
Query: 618 GPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAP----IKNQGSMVSEP---VK 670
VP P K+ P V P ++ + PE E + T ++ + + E +
Sbjct: 9881 EK-VPVPRKEVAPPVRVPEVPKE-LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT 9938
Query: 671 NQGLVVSGPVKDQDVV---VPEHAKVHDSAVVAPVKNQGPV--VPESVKNQDPILPVLVK 725
+ +V PVK +V VPE K V P K + P VPE K + +PVL+
Sbjct: 9939 EEEVVPVIPVKVPEVPRKPVPEEKK----PVPVPKKKEAPPAKVPEVPKKPEEKVPVLI- 9993
Query: 726 DQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGP--AVPEPLKTQG 783
P +PP + VPE K VP VP VPVP K + P VPE K
Sbjct: 9994 ---PKKEKPPPAK---VPEVPKKPVPEEKVP-------VPVPKKVEAPPAKVPEVPKKPV 10040
Query: 784 PRDPQLPTVSP----LPRVMIPTAP 804
P + ++P +P P +P P
Sbjct: 10041 P-EKKVPVPAPKKVEAPPAKVPEVP 10064
Score = 57.8 bits (138), Expect = 4e-08
Identities = 123/607 (20%), Positives = 205/607 (33%), Gaps = 93/607 (15%)
Query: 44 PQPPPPQQQAQPALAPPSARAVAIETQ-----PAQGELDAVARATGPAPGPTGEREPAAG 98
P PP + + P P + + V E + P + E+ P ++ P A
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAI 10654
Query: 99 PGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQK 158
P P P + V ++ A V+ PEP+ P+ P E++
Sbjct: 10655 P----PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVV 10710
Query: 159 DFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAA 218
+ P + P +PK V + P++ PK+ + P E++ A
Sbjct: 10711 AKKPELPPVKV--PEVPKEV----VPEKKVPLV-VPKKPEAPPAKVPEVPKEVVPEKKVA 10763
Query: 219 PGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRG 278
+ K ++ + + RAE E P A + PE +
Sbjct: 10764 VPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKP 10823
Query: 279 RAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSA 338
A+ EE + E + K V IK KP+ PP + +
Sbjct: 10824 VPVAE-------EEEPEVPPPAVPEEPKKIIPEKKVPVIK-KPEAPPPKEPEPEKVIEKP 10875
Query: 339 QFKGEASKPTTADNKVIDRRRIRSLYSEPFKE-PPKVEKPSVQSSKPKKTSASHKPTRKA 397
+ K P A K + +I L + P K+ P K + P P K K RK
Sbjct: 10876 KLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKL 10935
Query: 398 KDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVAT 457
++ KP+ KE+ + +
Sbjct: 10936 LPER------------------KPEPKEE----------------------VVLKSVLRK 10955
Query: 458 EPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKN 517
P++++ V P L E +KK P PPK + + V ++ +PEP K
Sbjct: 10956 RPEEEEPKVEPKKL--------EKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK- 11006
Query: 518 ESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMV 577
V + P++P+P P A+VK ++ P ++ + I PV P+V
Sbjct: 11007 --------VPEIKPAIPLPAPEPKPKPEAEVK---TIKPPPVEPEPTPIAAPV--TVPVV 11053
Query: 578 PAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIK 637
+ + P A+ K +GP+ P K P+P++ E + E P AP
Sbjct: 11054 GKKAEAKAPKEEAA-KPKGPIKGVPKK-----TPSPIEAERRKLRPGSGGEKPPDEAPFT 11107
Query: 638 DQDPMVP 644
Q VP
Sbjct: 11108 YQLKAVP 11114
Score = 54.7 bits (130), Expect = 3e-07
Identities = 114/512 (22%), Positives = 177/512 (34%), Gaps = 75/512 (14%)
Query: 313 PVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPF---- 368
P+ + P+ K P K + T + K +A K ++ R I P
Sbjct: 8964 PIPLLLPTPEEKKPPPKRIEVTKKAV--KKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Query: 369 -KEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKK------SAEGPST--- 418
K P ++ S T K +K K+ QA K+ S E P
Sbjct: 9022 AKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELE 9081
Query: 419 ----TKPDDKEQSKEMNNKLAEAKESLAQPVSDS------------SKTQGPVATEPDKD 462
T+P ++ +E + E K + V + + +G E + +
Sbjct: 9082 VEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWE 9141
Query: 463 QGSVVPGLLKGQGPMVQE------PLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLK 516
+ +++ Q + +E P K P PPK +I PV ++ ++
Sbjct: 9142 EAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPK----VIKKPVIEKIEKTSRRME 9197
Query: 517 NES------PVISAPVKDQGPS-VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEP 569
E P +S + Q PS PV + VPA V + V+ E E
Sbjct: 9198 EEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPA-VHTKKMVISEEKMFFASHTEEE 9256
Query: 570 VKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEG 629
V P V + E + A K P P + P PAP E VP P K E
Sbjct: 9257 VSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVP---ELPEKPAPE--EVAPVPIPKKVEP 9311
Query: 630 PMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPE 689
P P VPE PK P+ + P K V PV ++ + VP
Sbjct: 9312 PA---------PKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPE-VPKKPVPEEKIPVPV 9361
Query: 690 HAKVHDSAVVAPVKNQGPVVPESV-------KNQDPILPVLVKDQGPTVLQP-PKNQGRI 741
K P +G V E + ++ P +P + K + P +P P+ + +
Sbjct: 9362 AKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEV 9421
Query: 742 VPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGP 773
P P +P PVP ++ VPVP + P
Sbjct: 9422 PPPPKVPALPKKPVP--EEKVAVPVPVAKKAP 9451
Score = 53.5 bits (127), Expect = 8e-07
Identities = 91/403 (22%), Positives = 156/403 (38%), Gaps = 57/403 (14%)
Query: 319 AKPQYKPPDDKMVHETSYSAQFKGEASKPTT----ADNKVIDRRRIRSLYSEPFKEPP-K 373
A PQ P K V E A + P +V+ +++ + + + PP K
Sbjct: 10689 APPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAK 10748
Query: 374 VEKPSVQSSKPKKTSASHKP-TRKAKDKQAVSGQAAKKKSA----EGPSTTKPDDKEQSK 428
V + + KK + KP AK + ++K A E + P+ E+ +
Sbjct: 10749 VPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 429 EMNNKLAEA-KESLAQPVSDSSKTQGPVATEPDKDQGSV----VPGLLKGQGPMVQEP-- 481
E+ + A +E PV++ + + P P++ + + VP + K + P +EP
Sbjct: 10809 EIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 482 --LKKQGSVVPGPPKDLGPMIPLPVKD-------QDHTVPEPLKNESPVISAPVKDQGPS 532
+ ++ + P PP P P P K+ Q +P+ E P + V+
Sbjct: 10869 EKVIEKPKLKPRPP----PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLK 10924
Query: 533 VPVPPKNQSPMVPA-KVKDQGSVVPESLKDQGPRIPEP---------VKNQAPMVPAPVK 582
VP K ++P K + + VV +S+ + P EP VK A P P K
Sbjct: 10925 VPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPK 10984
Query: 583 DEGPMVSASVKDQGPMVSAPVK--DQGPIVPAPVKGEGP--------IVPAPVKDEGPMV 632
+ +V + + P K + P +P P P I P PV+ E +
Sbjct: 10985 PVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI 11044
Query: 633 SAPIKDQDPMVPEH-----PKDESAMATAPIKNQGSMVSEPVK 670
+AP+ P+V + PK+E+A PIK P++
Sbjct: 11045 AAPVTV--PVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIE 11085
Score = 51.2 bits (121), Expect = 4e-06
Identities = 106/476 (22%), Positives = 188/476 (39%), Gaps = 71/476 (14%)
Query: 366 EPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTK--PDD 423
+P P KVE P + PKK P ++++ + + + P + P++
Sbjct: 10073 KPTPVPKKVEAPPPKV--PKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE 10130
Query: 424 KEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGL-----LKGQGPMV 478
+E E L E +E + + + E + V+P + + P +
Sbjct: 10131 EEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEI 10190
Query: 479 QEPLKKQGSVVP----GPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVP 534
++ + ++ V+P PP + P +P V+++ +P+ E V+ V ++ P
Sbjct: 10191 KKKVTEKKVVIPKKEEAPPAKV-PEVPKKVEEKRIILPK----EEEVLPVEVTEEPEEEP 10245
Query: 535 VPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPV--KDEGPMVSASV 592
+ + + P P +++ V P PR+PE +K P P PV K E P S
Sbjct: 10246 IS-EEEIPEEPPSIEEVEEVAP-------PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSK 10297
Query: 593 KDQGPMVSAPV-KDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDES 651
K V PV K + P PA V P VP V ++ +V P K+ P E
Sbjct: 10298 KIPEEKVPVPVQKKEAP--PAKV----PEVPKKVPEKKVLV--PKKEAVPPAKGRTVLEE 10349
Query: 652 AMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHD----------SAVVAP 701
++ A Q +V E ++ + VV V++ +PE + H+ V
Sbjct: 10350 KVSVA--FRQEVVVKERLELE--VVEAEVEE----IPEEEEFHEVEEYFEEGEFHEVEEF 10401
Query: 702 VKNQGPVVPES--VKNQDPILPVLVKDQGPTVLQP------PKNQGRIVPEPLKNQVPIV 753
+K + V E V+ ++ V ++ +P P+ +I+P + P
Sbjct: 10402 IKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIP---PKKPPTK 10458
Query: 754 PVPLKDQDPLVP-VPAK---DQGPAVPEPLKTQGPRDPQ-LPTVSPLPRVMIPTAP 804
VP K+ VP VP K ++ VPE + + P+ LP +P +P P
Sbjct: 10459 VVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPP 10514
Score = 50.1 bits (118), Expect = 8e-06
Identities = 80/321 (24%), Positives = 128/321 (39%), Gaps = 39/321 (12%)
Query: 371 PPKV-EKPSVQSSKPKKTSASHKPTRKAKDKQAVSG--QAAKKKSAEGPSTTKPDDKEQS 427
PPKV +KP ++ K +KTS R ++K V+ + +KK + PS T +E+
Sbjct: 9177 PPKVIKKPVIE--KIEKTSR-----RMEEEKVQVTKVPEVSKKIVPQKPSRTPV--QEEV 9227
Query: 428 KEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGS 487
E+ K+ + S+ + A+ +++ VP + K + +E + S
Sbjct: 9228 IEVKVPAVHTKKMVI------SEEKMFFASHTEEEVSVTVPEVQKEI--VTEEKIHVAIS 9279
Query: 488 VVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAK 547
PP + + P ++ VP P K E P AP + P PVP + + VP K
Sbjct: 9280 KRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPP---APKVPEVPKKPVPEEKKPVPVPKK 9336
Query: 548 VKDQGSVVPESLKDQGP--RIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKD 605
VPE K P +IP PV + PA V P V V + + ++
Sbjct: 9337 EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKV----PEVQKGVVTEEKITIVTQRE 9392
Query: 606 QGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMV 665
+ P P VP K + P P+ ++ VP PK A+ P+ + V
Sbjct: 9393 ESP---------PPAVPEIPKKKVPEERKPVPRKEEEVPPPPK-VPALPKKPVPEEKVAV 9442
Query: 666 SEPVKNQGLVVSGPVKDQDVV 686
PV + V + VV
Sbjct: 9443 PVPVAKKAPPPRAEVSKKTVV 9463
Score = 47.8 bits (112), Expect = 4e-05
Identities = 109/487 (22%), Positives = 180/487 (36%), Gaps = 58/487 (11%)
Query: 313 PVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEP- 371
P K IK KP +K+ + + K + +K K++ ++ R+ E E
Sbjct: 9177 PPKVIK-----KPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVK 9231
Query: 372 -PKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
P V + S+ K ASH + V + ++ + + + + E+
Sbjct: 9232 VPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPEL 9291
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVP 490
K A E +A PV K + P P+ + V P ++P+
Sbjct: 9292 PEK--PAPEEVA-PVPIPKKVEPPAPKVPEVPKKPV---------PEEKKPVPVPKKEPA 9339
Query: 491 GPPKDLGPMIPL-PVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVK 549
PPK P +P PV ++ VP K E+P P +G V + + +V + +
Sbjct: 9340 APPKV--PEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG----VVTEEKITIVTQREE 9393
Query: 550 DQGSVVPESLKDQGPRIPEPVKNQA------PMVPA----PVKDEGPMVSASVKDQGPMV 599
VPE K + P +PV + P VPA PV +E V V + P
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPP 9453
Query: 600 SAPVKDQGPIVPAPVKGEGPI---VPAPVKDEGPMVSAPIK------DQDPMVPEHPKDE 650
A V + + E + VP V+ VSA + ++ + + ++E
Sbjct: 9454 RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEE 9513
Query: 651 SAMATAPIKNQGSMVSEP----VKNQGLVVSGPVKDQDVVVPEHAK---VHDSAVVAPVK 703
+ ++ EP V+ + ++S V+ + V E + V + A ++
Sbjct: 9514 REEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIE 9573
Query: 704 NQGPV-VPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDP 762
P VPE+ K P V + PPK VPE K VP VP K
Sbjct: 9574 EPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK-----VPEEPKKPVPEKKVPPKVIKM 9628
Query: 763 LVPVPAK 769
P+PAK
Sbjct: 9629 EEPLPAK 9635
Score = 44.7 bits (104), Expect = 4e-04
Identities = 141/659 (21%), Positives = 239/659 (36%), Gaps = 117/659 (17%)
Query: 164 PLPRRGDHPWIP-----KPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAA 218
P P+ + P P KPV + A+ P + ++P +E+ PV A +++EA
Sbjct: 9312 PAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVA---KKKEAP 9368
Query: 219 PGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRG 278
P + G + +E+ T IV + E++P PA PE +
Sbjct: 9369 PAKVPEVQKGVVT--EEKIT--------IVTQ-----REESPPPAV--------PEIPKK 9405
Query: 279 RAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSA 338
+ + +EE ++ P + A P+ P++K+ +
Sbjct: 9406 KVPEERKPVPRKEE-----------------EVPPPPKVPALPKKPVPEEKVAVPVPVAK 9448
Query: 339 QF---KGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPT- 394
+ + E SK T V++ +R + F P +VE + S ++ S S +
Sbjct: 9449 KAPPPRAEVSKKT-----VVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503
Query: 395 ------RKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQ--SKEMNNKLAEAKESLAQPVS 446
R+ + ++ + + + E P ++K SK + + AE E + +
Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIV 9563
Query: 447 DSSKT-------------QGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPP 493
K + P P+K + VP K P V E KK PP
Sbjct: 9564 LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP 9623
Query: 494 KDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGS 553
K + PLP K + + + E V+ A K + PPK + P P + +
Sbjct: 9624 KVIKMEEPLPAKVTERHM--QITQEEKVLVAVTKKE-----APPKARVPEEPKRAVPEEK 9676
Query: 554 VVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAP 613
V LK + R EP PA V + V VK++ + AP ++ PI
Sbjct: 9677 V----LKLKPKREEEP--------PAKVTEFRKRV---VKEEKVSIEAPKREPQPIKEVT 9721
Query: 614 VKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATA---PIKNQGSMVSEPVK 670
+ E +++E V + ++ ++ + E T + E +
Sbjct: 9722 IMEEKERA-YTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYE 9780
Query: 671 NQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPT 730
++ P K V V P K VPE K PI P +K P
Sbjct: 9781 EHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEE-KVPVPI-PKKLKPPPPK 9838
Query: 731 VLQPPKN--QGRI---VPEPLKNQV--PIVPVPLKDQ----DPLVPVPAKDQGPAVPEP 778
V + PK + +I + + K QV P VP+K + + VPVP K+ P V P
Sbjct: 9839 VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVP 9897
Score = 39.7 bits (91), Expect = 0.011
Identities = 51/223 (22%), Positives = 87/223 (39%), Gaps = 25/223 (11%)
Query: 588 VSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
V V ++ P K P P K ++ PV ++ S ++++ V + P
Sbjct: 9152 VQKEVYEESHERKVPAKVPEKKAPPPPK----VIKKPVIEKIEKTSRRMEEEKVQVTKVP 9207
Query: 648 KDESAMATAPIKNQGSMVSEPVKNQGLVVSGP-VKDQDVVVPEHAKVHDSAVVAPVKNQG 706
E + P K + PV+ + + V P V + +V+ E S V
Sbjct: 9208 --EVSKKIVPQKPSRT----PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTV 9261
Query: 707 PVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPV 766
P V + + ++ I + K ++PP + +P +V VP+P K + P V
Sbjct: 9262 PEVQKEIVTEEKIHVAISKR-----VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKV 9316
Query: 767 PAKDQGPA------VPEPLKTQG--PRDPQLPTVSPLPRVMIP 801
P + P VP P K P+ P++P P+P IP
Sbjct: 9317 PEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPK-KPVPEEKIP 9358
Score = 37.4 bits (85), Expect = 0.056
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 531 PSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSA 590
P +P PK++SP P + + + + P PV++ P+PV+ P
Sbjct: 255 PRIPPKPKSRSP-TPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARI 313
Query: 591 SVKDQGPMVSAPVKD-QGPIV----PAPVKGEGPIVPAPVKDEGPMVSA 634
S ++P++ + P++ A GP VP P K EG + S+
Sbjct: 314 S--------TSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASS 354
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 67.8 bits (164), Expect = 4e-11
Identities = 82/339 (24%), Positives = 116/339 (34%), Gaps = 31/339 (9%)
Query: 475 GPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVP 534
G + P G+ +P PP G IPLP +P P I P G +P
Sbjct: 939 GAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998
Query: 535 VPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKD 594
PP +P G+ +P G IP P P+ A + P+ A +
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPP 1054
Query: 595 QGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPM----VPEHPKDE 650
P+ A + P+ A + P+ A + P+ A I P+ +P P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114
Query: 651 SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVP 710
A P G+ + P G + P V +P + + + P G +P
Sbjct: 1115 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP 1174
Query: 711 ESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKD 770
P LP G + PP G +P P P+P P P+P
Sbjct: 1175 -----PPPPLP------GVGIPPPPPLPGVGIPPP-------PPLPGAGIPPPPPLPGMG 1216
Query: 771 QGPAVPEPLKTQG---PRDPQLPTVSP--LPRVMIPTAP 804
PA PL G P P LP P LP+V T P
Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255
Score = 53.9 bits (128), Expect = 6e-07
Identities = 76/322 (23%), Positives = 107/322 (33%), Gaps = 23/322 (7%)
Query: 464 GSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVIS 523
G +P L G G PL G+ +P PP G IP P +P P I
Sbjct: 963 GIPLPPPLPGAGIPPPPPLP--GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 524 APVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKD 583
P G +P PP +P G+ +P G IP P P+ A +
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPP 1076
Query: 584 EGPMVSASVKDQGPMVSAPVKDQGPIV------PAPVKGEGPIVPAPVKDEGPMVSAPIK 637
P+ A + P+ A + P+ P P+ G G P P+ G P+
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136
Query: 638 DQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSA 697
+P P P G+ + P G + P V +P +
Sbjct: 1137 GAG--IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194
Query: 698 VVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPL 757
+ P G +P P LP + P PP G I P PL +P+ PL
Sbjct: 1195 IPPPPPLPGAGIP-----PPPPLPGMGIPPAPAPPLPPPGTG-IPPPPL---LPVSGPPL 1245
Query: 758 KDQDPLVPVPAKDQGPAVPEPL 779
Q +P +P PL
Sbjct: 1246 LPQVGSSTLPTPQVCGFLPPPL 1267
Score = 45.1 bits (105), Expect = 3e-04
Identities = 175/834 (20%), Positives = 271/834 (32%), Gaps = 148/834 (17%)
Query: 45 QPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGP 104
+P PQQ PPS + + P+ L A A +P T P AGPG
Sbjct: 286 EPREPQQ-------PPSPGGLPVSEAPS---LPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335
Query: 105 G-PGLGSGSTSGPADSVMRQDY------RAWKVQRPEPSCR-----PRSEYQPSDAPFER 152
G P G+G T + +D W + E + + P E Q DAP
Sbjct: 336 GAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAA 395
Query: 153 E-----TQYQKDFRAWPLPR----RGDHPWIPKPVQISAASQASAPILGAPKRRPQ-SQE 202
Q+ F+ +PL + + P + S +P + KRRP+ S
Sbjct: 396 SLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRI---KRRPEPSLS 452
Query: 203 RWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLP 262
R A A GGLAAG + AD W E LG +TP
Sbjct: 453 RGSRTALASVAAPAKKHRADGGLAAGLSRSAD-----------W----TEELG-ARTPRV 496
Query: 263 AAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQ 322
A + G + G + AL + A A + ++N F T +
Sbjct: 497 GGSAHLLERGVASDSGGGVSPAL--AAKASGAPAAADGFQNVFTGRTLL----------- 543
Query: 323 YKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEP----PKVEKPS 378
E +S Q G + +++I + +S+ F+EP + S
Sbjct: 544 ----------EKLFSQQENGPPEEAEKFCSRIIAMGLLLP-FSDCFREPCNQNAQTNAAS 592
Query: 379 VQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAK 438
+ +A +PT + GQ ++ + GP + PD++ + ++ + A
Sbjct: 593 FDQDQLYTWAAVSQPTHSLDYSE---GQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAV 649
Query: 439 ESLAQPVSDSSKTQGPVATEPDKDQGSVVPGL-------------LKGQGPMVQEPLKKQ 485
Q SD+ Q V + Q +V+ L L+ Q P + +
Sbjct: 650 SETPQKRSDA--VQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASG 707
Query: 486 GSVVPGPPKDLGPM----IPLPVKDQDH-------TVPEPLKNESPVISAPVKDQGPSVP 534
+ G + + L K+ H ++ E V++ P D P P
Sbjct: 708 HQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRP 767
Query: 535 VPPKNQSPMVPAKVKDQGSVV--PESLKDQ-GPRIPEPVKNQAPMVPAPVKDEG------ 585
P K + S++ P + Q P +Q P P+ + G
Sbjct: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGS 827
Query: 586 -PMVSASVKDQGP---MVSAPVKDQGPIVPAP----------VKGEGPIVPAPVKDEGPM 631
P S S + Q VS+ K+ I P + G G + P P G
Sbjct: 828 QPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMT 887
Query: 632 VSAPIKDQDPMVPEHPKDES-AMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEH 690
V P P E P+ G P+ G++ P+ +P
Sbjct: 888 VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG--IPPP 945
Query: 691 AKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQV 750
+ +A+ P G +P P LP G + PP G +P P
Sbjct: 946 PPLPGAAIPPPPPLPGAGIP-----LPPPLP------GAGIPPPPPLPGAGIPPPPPLPG 994
Query: 751 PIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAP 804
+P P +P P G +P P G P P PLP IP P
Sbjct: 995 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPP 1045
Score = 31.2 bits (69), Expect = 4.0
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 7/86 (8%)
Query: 27 PLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPA 86
PL T+ S + G P PPPP P + P+ + AI P + + P
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPP----LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 87 PG---PTGEREPAAGPGRSGPGPGLG 109
PG P P AG P PG G
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAG 941
Score = 30.8 bits (68), Expect = 5.3
Identities = 26/84 (30%), Positives = 28/84 (33%), Gaps = 6/84 (7%)
Query: 41 GAPPQPPPPQQQAQPA----LAPPSARAVAIETQPAQGE--LDAVARATGPAPGPTGERE 94
G PP PP P PA L PP P G L V +T P P G
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLP 1264
Query: 95 PAAGPGRSGPGPGLGSGSTSGPAD 118
P G G G GS P +
Sbjct: 1265 PPLPSGLFGLGMNQDKGSRKQPIE 1288
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 64.7 bits (156), Expect = 3e-10
Identities = 168/853 (19%), Positives = 285/853 (33%), Gaps = 149/853 (17%)
Query: 44 PQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSG 103
PQP PP QA P P + ++T P + T P P + PA P
Sbjct: 211 PQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ 269
Query: 104 PGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAW 163
P + + + P+P + + +D
Sbjct: 270 SHPPIIAAT--------------------PQPVKTKKGVKRKADTTTPTTID-------- 301
Query: 164 PLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAG 223
P+ P PK ++ ++S P+ K P SQ+ + +++ EQ G
Sbjct: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI- 360
Query: 224 GLAAGKASGADERDTRRKAGPAW------------------IVRRAEGLGHEQTPLPAAQ 265
E ++ A AW I++ + ++ L A +
Sbjct: 361 ---------LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEARE 411
Query: 266 AQ-VQATGPEAGRGRAAADALNRQIREEVASA--VSSSYRNEFRAWTDIKPVKPIKA--K 320
+ Q G + + N E VA A + + F D +P +P+ A
Sbjct: 412 YRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPD-EPEEPVVAVSS 470
Query: 321 PQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFK----------- 369
P PP + +S + + ++ D+ +R + + E K
Sbjct: 471 PAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQ 530
Query: 370 ----EPPKVEKPSVQSSKPK-----------KTSASHKPTRKAKDKQAVSGQAAKKKSA- 413
+P K EK + K K K+ A P +K K + + +KK+ A
Sbjct: 531 PQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAP 590
Query: 414 ---EGPSTTKPDDKEQSKEMN-----------NKLAEAK----ESLAQPVSDSSKTQGPV 455
+ P T + +++++ K M+ NKL K + Q S K P
Sbjct: 591 MKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPD 650
Query: 456 ATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-------SVVPGPPKDLGPMIPLPVKDQD 508
E D + ++ P L+ V L+K+ V+ G K G +
Sbjct: 651 EIEIDFE--TLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSE 708
Query: 509 HTVPEPLKNESPVISAPVKDQGPSVPVPPKN-----QSPMVPAKVKDQGSVVPESLKDQG 563
+ + +E+ + K P + Q PA V Q P+ Q
Sbjct: 709 SSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQ----QP 764
Query: 564 PRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPA 623
P P P + Q P P P + ++K P P + V P +P
Sbjct: 765 PPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP----------PFIATQVPVLEPQLPG 814
Query: 624 PVKDEGPMVSAPIKD-QDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGL--VVSGPV 680
V D + PI P +P H +T P NQ ++VS P + L S P
Sbjct: 815 SVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPS 874
Query: 681 KDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGR 740
+ P+ A+ V+P Q P++P+ Q P VL++D+ P Q +
Sbjct: 875 NRAAALPPKPAR---PPAVSPALTQTPLLPQPPMAQPP--QVLLEDEEPPAPPLTSMQMQ 929
Query: 741 IVPEPLKN---QVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPR 797
+ + L+ P++P P P+P P+V + L+ Q P P P P P+
Sbjct: 930 LYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH-PSVQQQLQQQPPPPPP-PQPQPPPQ 987
Query: 798 VMIPTAPHTEYIE 810
P +++
Sbjct: 988 QQHQPPPRPVHLQ 1000
Score = 61.6 bits (148), Expect = 3e-09
Identities = 103/481 (21%), Positives = 168/481 (34%), Gaps = 61/481 (12%)
Query: 312 KPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEP 371
K P+K+KP PP + E E + + NK+ + R ++ +EP
Sbjct: 586 KEPAPMKSKP---PPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP 642
Query: 372 PKVEKPSVQSSKPKKTSASH---KPTRKAKDKQAVSGQAAKKKSAE--------GPSTTK 420
S+++S P + KP+ + ++ V+ KK+ + G S K
Sbjct: 643 ------SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMK 696
Query: 421 PDDKEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQE 480
+S+ + + E ++ SK +G E K + + P+ Q+
Sbjct: 697 GFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQ 756
Query: 481 PLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGP------SVP 534
P P PP+ P P P + Q P P P +AP P VP
Sbjct: 757 P--------PPPPQQ--PPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP 806
Query: 535 VPPKNQSPMVPAKVKDQGSVVPESL-----KDQGPRIPEPVKNQAP------MVPAPVKD 583
V P +P V D + + + P +P+P ++ P V +P
Sbjct: 807 V----LEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
Query: 584 EGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMV 643
+ + + P K P +P + P++P P + P V ++D++P
Sbjct: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL--LEDEEPPA 920
Query: 644 PEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHD--SAVVAP 701
P P M + Q P+ V S P + P H V P
Sbjct: 921 P--PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP--PPPLPPPPHPSVQQQLQQQPPP 976
Query: 702 VKNQGPVVPESVKNQDPILPVLVKDQ--GPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKD 759
P P ++Q P PV ++ + QPP QG+ P P Q P P P K
Sbjct: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKP 1036
Query: 760 Q 760
Q
Sbjct: 1037 Q 1037
Score = 49.3 bits (116), Expect = 1e-05
Identities = 88/357 (24%), Positives = 126/357 (35%), Gaps = 64/357 (17%)
Query: 474 QGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSV 533
Q P P V PP + P + + P K P +P Q P +
Sbjct: 841 QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL 900
Query: 534 PVPPKNQSPMV-------PA----------------KVKDQGSVVPESLKDQG---PRIP 567
P PP Q P V PA KV+ ++P S+K Q P +P
Sbjct: 901 PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP-SVKVQSQPPPPLP 959
Query: 568 EP----VKNQAPMVPAPVKDEGPMVSASVKDQGP-------------MVSAPVKDQGPIV 610
P V+ Q P P P + Q P + P QG
Sbjct: 960 PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019
Query: 611 PAPVKGEGPIVPAPVKDEGPMV---SAPIKDQDPMVPEHPKDESA--MATAPIKNQGSMV 665
P P G+ P P P K + + S DP H ++ + M +P +Q +
Sbjct: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
Query: 666 ---SEPVKN-----QGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQD 717
S P +N Q L + V+ Q +VV + K+H S ++ + PE K+ +
Sbjct: 1080 THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH-SPIIRSEPFSPSLRPEPPKHPE 1138
Query: 718 PILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKD---QDPLVPV-PAKD 770
I + Q P + P + GR V P + P P KD Q+P PV P KD
Sbjct: 1139 SIKAPVHLPQRPEM--KPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKD 1193
Score = 38.9 bits (89), Expect = 0.019
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 13/68 (19%)
Query: 40 PGAPPQP-PPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAG 98
P PPQP PPPQQQ QP P + + T Q P P G++ P
Sbjct: 976 PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQ------------PPPPQGQQPPHPP 1023
Query: 99 PGRSGPGP 106
PG+ P P
Sbjct: 1024 PGQQPPPP 1031
Score = 38.1 bits (87), Expect = 0.033
Identities = 54/215 (25%), Positives = 78/215 (36%), Gaps = 32/215 (14%)
Query: 366 EPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKE 425
+P PP + P Q +KP++ H R K +G E PS +
Sbjct: 1018 QPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL-----REAPSPLMIHSPQ 1072
Query: 426 QSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQ-EPLKK 484
S+ + + QP + V +P VV K P+++ EP
Sbjct: 1073 MSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQP-----LVVVKEEKIHSPIIRSEPFSP 1127
Query: 485 QGSVVPGPPK---DLGPMIPLPVK------DQDHTVPEPLKNESPVISAPVKD---QGPS 532
S+ P PPK + + LP + D V P + +P AP KD Q P
Sbjct: 1128 --SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPK 1185
Query: 533 VPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIP 567
PV PK K+K+ GS SL + P P
Sbjct: 1186 TPVAPKKD-----LKIKNMGSWA--SLVQKHPTTP 1213
Score = 35.0 bits (79), Expect = 0.28
Identities = 58/248 (23%), Positives = 90/248 (36%), Gaps = 37/248 (14%)
Query: 27 PLVFTKYSEATEHPGA--PPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARA-T 83
P+ F+ + + P PP PPP QQ P A P + + P + D +
Sbjct: 1001 PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ-QVIQHHHSPRHHKSDPYSTGHL 1059
Query: 84 GPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSVM--RQDYRAWKVQRPEPSCRPRS 141
AP P P +S S P +V +Q+ RA V +P+P +
Sbjct: 1060 REAPSPLMIHSPQMSQFQS-------LTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKE 1112
Query: 142 EYQPSDAPFERETQYQKDFRAWPLPRRGDHP-WIPKPVQISAASQASAPILGAPKRRPQS 200
E +P R + R P HP I PV + + +G P RP
Sbjct: 1113 E--KIHSPIIRSEPFSPSLR----PEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPE 1166
Query: 201 QERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRKAGPAW--IVRRAEGLGHEQ 258
Q P A + +Q+ P K A ++D + K +W +V++ H
Sbjct: 1167 QNA-PPPGAPDKDKQKQEP---------KTPVAPKKDLKIKNMGSWASLVQK-----HPT 1211
Query: 259 TPLPAAQA 266
TP A++
Sbjct: 1212 TPSSTAKS 1219
Score = 31.6 bits (70), Expect = 3.1
Identities = 53/216 (24%), Positives = 73/216 (33%), Gaps = 40/216 (18%)
Query: 27 PLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPA 86
P++ E H PP+ P Q A+ P A A+ QP++ A A PA
Sbjct: 826 PILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
Query: 87 PGPTGEREPAAGPGRSG----PGPGLG---------SGSTSGPADSVMRQDY--RAWKVQ 131
R PA P + P P + + P S+ Q Y + KVQ
Sbjct: 886 ------RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQ 939
Query: 132 RPE---PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIP------------- 175
P PS + +S+ P P Q+ + P P P P
Sbjct: 940 PPTPLLPSVKVQSQ-PPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
Query: 176 -KPVQISAASQASAPILG-APKRRPQSQERWPVQAA 209
+P+Q S Q P G P P Q+ P Q A
Sbjct: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPA 1034
Score = 30.8 bits (68), Expect = 5.3
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 7/81 (8%)
Query: 734 PPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQ-LPTV 792
PP+ Q P P Q P P D +V P P P+PL+T P PQ P
Sbjct: 205 PPQTQTP-QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP--PQPLQTPPPVPPQPQPPP 261
Query: 793 SPLPRVMIPTAPHTEYIESSP 813
+P P+ P H I ++P
Sbjct: 262 APAPQ---PVQSHPPIIAATP 279
Score = 30.0 bits (66), Expect = 9.0
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 38 EHPGAPPQ---PPPPQQQAQPALAPPSARAVAIETQPA 72
+ P PPQ PPPP QQ Q PP ++ + PA
Sbjct: 755 QQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 63.5 bits (153), Expect = 7e-10
Identities = 123/526 (23%), Positives = 172/526 (32%), Gaps = 140/526 (26%)
Query: 371 PPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEM 430
PP+ E+P T + T A D SGQ G + Q M
Sbjct: 586 PPEPEEPEADQHLLPPTLPT-SATSLASDSTFDSGQ--------GSTVYSDSQSSQQSVM 636
Query: 431 NNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVP 490
LA+A S AQ V ++GPV + G+ +Q + P
Sbjct: 637 LGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAY-----------------QQPTAAP 679
Query: 491 GPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQ--GPSVPVPPKNQSPMVPAKV 548
G P P P Q H P+P + +PV+ P GP P PP Q P +
Sbjct: 680 GLPVGSVPAPACPPSLQQH-FPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLA--- 735
Query: 549 KDQGSVVPESLKDQGPRIP-EPVKNQAPMVPAPVKDEG----------PMVSASVKDQGP 597
Q + +P+ L Q P +P +PV P AP G P Q P
Sbjct: 736 --QPTPLPQVLAPQ-PVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVP 792
Query: 598 MVSAPVKDQGPIVP-APVKGEGPIVP-------APVKDEG--------PMVSAPIKDQDP 641
P+ PI P A + G P +P PV P ++AP+ P
Sbjct: 793 PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASP 852
Query: 642 MVP------EHPKDE-----------SAMATAPI--------------KNQGSMVSEPVK 670
+P HP +A AT P+ + +PV
Sbjct: 853 ALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVY 912
Query: 671 NQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPT 730
P DV H V + P Q + P+ P+LP P
Sbjct: 913 PAAFPQMAPT---DVPPSPHHTVQNMRATPP---QPALPPQPTLPPQPVLP-------PQ 959
Query: 731 VLQPPKNQGRIVPEPLKNQVPIVPV-------PLKDQDPLVPVPAKDQGPAVPE---PLK 780
PP Q + P+P + P++P P+ P +PV + P +PE P
Sbjct: 960 PTLPP--QPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAA 1017
Query: 781 TQGPR-------------DPQLPTVS---------PLPRVMIPTAP 804
T G + Q+PTV PLP V++P AP
Sbjct: 1018 TPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAP 1063
Score = 54.3 bits (129), Expect = 4e-07
Identities = 59/209 (28%), Positives = 87/209 (41%), Gaps = 37/209 (17%)
Query: 610 VPAPVKGEGPIVPAPVK---------DEGPMVSAPIKDQDPMVPEHPKDESAMATAPI-- 658
V +P K GP VP V+ P P DQ + P P +++A+
Sbjct: 558 VGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFD 617
Query: 659 KNQGSMV-SEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKN-- 715
QGS V S+ +Q V+ G + D P A+ V +P ++GPV+P+S+ +
Sbjct: 618 SGQGSTVYSDSQSSQQSVMLGSLAD---AAPSPAQ----CVCSPPVSEGPVLPQSLPSLG 670
Query: 716 ---QDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQG 772
Q P L P PP Q P+P + P++P P P+P G
Sbjct: 671 AYQQPTAAPGLPVGSVPAPACPPSLQQHF-PDPAMSFAPVLP------PPSTPMPT---G 720
Query: 773 PAVPEPLKTQGPRDPQLPTVSPLPRVMIP 801
P P P G + P L +PLP+V+ P
Sbjct: 721 PGQPAP---PGQQPPPLAQPTPLPQVLAP 746
Score = 40.4 bits (93), Expect = 0.007
Identities = 113/524 (21%), Positives = 175/524 (33%), Gaps = 117/524 (22%)
Query: 31 TKYSEATEHPGAPPQPPPPQQQA--QPALAPPSARAVAIETQPAQGELD-AVARATGPAP 87
T+ + A P PP P P QPAL P+ A A G + A ++ P
Sbjct: 1465 TRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA-----AVGAVSLATSQLPSPPL 1519
Query: 88 GPTGEREPAAGPGRSGPGPGLGSG---STSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQ 144
GPT +P + G GP G ST D +R ++ P S + +
Sbjct: 1520 GPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRT--LLYQEHVPTSSASAGTPVE 1577
Query: 145 PSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERW 204
D F E P RGD P ++ A P+ PK + +
Sbjct: 1578 VGDRDFTLE------------PLRGDQP----RSEVCGGDLALPPV---PKEAVSGRVQL 1618
Query: 205 PVQAAAEAREQEAAPGGAGGLAAGKASGAD-----------ERDTRRKAGPAWIVRRAEG 253
P Q E + E AP + G +S +RD R+ A + +V
Sbjct: 1619 P-QPLVE--KSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVP- 1674
Query: 254 LGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKP 313
+ P A+V+ T + G ++
Sbjct: 1675 ---QDVPAFVRPARVEPTDRDGGEAGESS------------------------------- 1700
Query: 314 VKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPK 373
A+P PP D G+AS P T + + R R +
Sbjct: 1701 -----AEP---PPSDM--------GTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKT 1744
Query: 374 VEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK 433
V + SV S++ + T AS R + +A PS+ PD K +
Sbjct: 1745 VGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEA--------PSS--PDVKLAVRRAQTA 1794
Query: 434 LAEAKESLAQPVSDSSKTQGPVATEPDKDQ------GSVVPGLLKGQGPMVQEPLKKQGS 487
+ + + +PVS S +GP A P + Q GSV +K +Q P + GS
Sbjct: 1795 -SSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRP-SRAGS 1852
Query: 488 VVPGPPKDLGPMIPLPVKDQDHTVPEPLK--NESPVISAPVKDQ 529
+ P P +G +P H+ + N+S + A +K +
Sbjct: 1853 LGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKE 1896
Score = 32.0 bits (71), Expect = 2.4
Identities = 47/211 (22%), Positives = 74/211 (35%), Gaps = 22/211 (10%)
Query: 611 PAPVKGEG--PIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEP 668
PAP E P+ + + E SAP KDQ + S +A+ + +Q + P
Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQ----LSSKEQPSFLASQQLLSQAGPSNPP 1377
Query: 669 -VKNQGLVVSGP---VKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQ-DPILPVL 723
L S P QD P + + + A + GP P+ + ++ + P+
Sbjct: 1378 GAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLA 1437
Query: 724 VKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQG 783
+ P +QP + P P P P + P PEP G
Sbjct: 1438 ETHEAPLAVQPL----------VVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSG 1487
Query: 784 PRDPQLPTVSP-LPRVMIPTAPHTEYIESSP 813
P L +P LP + + T + S P
Sbjct: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPP 1518
Score = 31.6 bits (70), Expect = 3.1
Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 23/75 (30%)
Query: 40 PGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGP 99
PGAPP P LAP S A+ D A AT P EPA+G
Sbjct: 1377 PGAPPAP----------LAPSSPPVTALPQ-------DGAAPATSTMP------EPASGT 1413
Query: 100 GRSGPGPGLGSGSTS 114
GPG G TS
Sbjct: 1414 ASQAGGPGTPQGLTS 1428
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 62.4 bits (150), Expect = 2e-09
Identities = 73/356 (20%), Positives = 150/356 (42%), Gaps = 63/356 (17%)
Query: 314 VKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTA--DNKVIDRRRIRSLYSEPFKEP 371
V+ K K Q+K ++ ++ ET + K E + TA + + + + +E +E
Sbjct: 441 VEAPKLKVQHKFVEE-IIEETKVEDE-KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 498
Query: 372 PKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMN 431
P+ E+ V + K + + + + +K+ GQ +++ EG + + ++ KE +
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 558
Query: 432 NKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPG 491
++ E ++ + +++ + E ++ S +E K+ V
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS-------------EEVATKEELVA-- 603
Query: 492 PPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG----PSVPVPPKNQSPMVPAK 547
D V +P K +SPV +PV+++G P PV K +SP+ +
Sbjct: 604 ----------------DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 647
Query: 548 VKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQG 607
V+++G K P+ P K ++P+ +PV++ K + P+ +PV++
Sbjct: 648 VEEKG-------KSPVPKSPVEEKGKSPVSKSPVEE---------KAKSPVPKSPVEE-- 689
Query: 608 PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKD--ESAMATAPIKNQ 661
A K E ++E + AP +++ E PKD E A +P+K +
Sbjct: 690 ----AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 741
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 62.4 bits (150), Expect = 2e-09
Identities = 73/356 (20%), Positives = 150/356 (42%), Gaps = 63/356 (17%)
Query: 314 VKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTA--DNKVIDRRRIRSLYSEPFKEP 371
V+ K K Q+K ++ ++ ET + K E + TA + + + + +E +E
Sbjct: 65 VEAPKLKVQHKFVEE-IIEETKVEDE-KSEMEEALTAITEELAVSMKEEKKEAAEEKEEE 122
Query: 372 PKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMN 431
P+ E+ V + K + + + + +K+ GQ +++ EG + + ++ KE +
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS 182
Query: 432 NKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPG 491
++ E ++ + +++ + E ++ S +E K+ V
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS-------------EEVATKEELVA-- 227
Query: 492 PPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQG----PSVPVPPKNQSPMVPAK 547
D V +P K +SPV +PV+++G P PV K +SP+ +
Sbjct: 228 ----------------DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 271
Query: 548 VKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQG 607
V+++G K P+ P K ++P+ +PV++ K + P+ +PV++
Sbjct: 272 VEEKG-------KSPVPKSPVEEKGKSPVSKSPVEE---------KAKSPVPKSPVEE-- 313
Query: 608 PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKD--ESAMATAPIKNQ 661
A K E ++E + AP +++ E PKD E A +P+K +
Sbjct: 314 ----AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 62.4 bits (150), Expect = 2e-09
Identities = 165/717 (23%), Positives = 248/717 (34%), Gaps = 122/717 (17%)
Query: 22 ADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVAR 81
A + V TK S A + AP + Q + PP+ RA E + E + +
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESE 280
Query: 82 ATGPAPGPTGER--------EPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRP 133
PA + + A+ P + PG G + + G A +V Q K +P
Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQT----KAGKP 335
Query: 134 EPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQAS--APIL 191
E SE + SD+ E ET K L + K Q+ AAS + +P
Sbjct: 336 EEDSESSSE-ESSDS--EEETPAAKAL----LQAKAS----GKTSQVGAASAPAKESPRK 384
Query: 192 GAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRK-AGPAWIVRR 250
GA P +A A RE+++ ++ ++ +E + K +G A VR
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQS------SSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 251 AEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTD 310
A E AA A + TGP AA + +Q + +S+ S E A +
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP-----AAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
Query: 311 IKPVKPIKAKPQYKPPD----------------------------DKMVHETSYSAQFKG 342
VKP+ PQ KP K ++ S++
Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
Query: 343 EASK---PTT---ADNKVIDRRRIRSLYSEPFKEPPKVEKP---SVQSSKPKKTSASHKP 393
++S PT A K + S P K PP+ P V++ KP S S +
Sbjct: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
Query: 394 TRKAKDKQAVSG--QAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKT 451
+ + D + AA+ K A TK K+ + + K+A + P + T
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
Query: 452 QGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-SVVPGPPKDLGPMIPLPVKDQDHT 510
P + P G+ P +K G +V G K +G L VK
Sbjct: 674 -SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK--GLQVK----- 725
Query: 511 VPEPLKNESPVISAPVK---DQGPSVPVPPKNQSPMV----PAKVKDQGSVVPESLKDQG 563
S PVK QG + PV P P V K +D S ES ++
Sbjct: 726 ----------AASVPVKGSLGQG-TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 564 PRIPEPVKN--------------QAPMVPAPVKDEGPMVSAS--VKDQGP-MVSAPVKD- 605
P VK +AP + G +V+A+ K + P V PV++
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 606 QGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQG 662
Q V A P V V + P +D E +E A A +K G
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Score = 57.8 bits (138), Expect = 4e-08
Identities = 141/724 (19%), Positives = 225/724 (31%), Gaps = 172/724 (23%)
Query: 52 QAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSG 111
+ +P++ P +A ++ T+ ++ AR PAPG G+ P G P
Sbjct: 213 EGKPSVKPAQVKASSVSTK------ESPARKAAPAPGKVGDVTPQVKGGALPPAK----- 261
Query: 112 STSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH 171
RA K + S SE + +AP +Q +
Sbjct: 262 --------------RAKKPEEESESSEEGSESE-EEAPAGTRSQVKAS------------ 294
Query: 172 PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKAS 231
K +Q+ AAS AP G P + A PG AG +A+ +
Sbjct: 295 ---EKILQVRAAS---APAKGTPGKGATP----------------APPGKAGAVASQTKA 332
Query: 232 GADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIRE 291
G E D+ + E+TP A Q +A+G + G A+A A +E
Sbjct: 333 GKPEEDSESSS-------EESSDSEEETPAAKALLQAKASGKTSQVGAASAPA-----KE 380
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTAD 351
+ P P K P E S S+ + ++ + A
Sbjct: 381 SPRKGAA--------------PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 352 NKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKK 411
K P + P+V S + + + A+ P RK A +++
Sbjct: 427 AK-------------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 412 SAEGPSTTKPDDKEQSKEMN-------NKLAEAKESLAQPVSDSSKTQGPVAT------- 457
+ S D+E MN K + K + + K GPV
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 458 --------EPDKDQGS--------------VVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
E D + S V P K G ++Q K S GPP+
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ--AKPTSSPAKGPPQK 591
Query: 496 LGPMI-------PLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV 548
GP+ P+ + + +E + P++ +P Q+ P K
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKT 648
Query: 549 KDQGS--VVPESLKDQGPRIPEPVKNQAPMVPA-------PVKDEGPMVSASVKDQGPMV 599
S V P + Q PR + A PA P +D + +++ +
Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGL 708
Query: 600 SAPVKD--------QGPIVPAPVKGE-----GPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
+ V Q PVKG P++P V A K +D E
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-KQEDSESSEE 767
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
D A +P + + S+ K P + P KV +A A ++
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP--GKVVTAAAQAKQRSPS 825
Query: 707 PVVP 710
V P
Sbjct: 826 KVKP 829
Score = 48.9 bits (115), Expect = 2e-05
Identities = 151/714 (21%), Positives = 237/714 (33%), Gaps = 112/714 (15%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P + + + A A+ A G+ V A+ PA + A PG
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDF 160
++GP +A +R E S +S + SD+ E Q +
Sbjct: 393 KTGPAVA------------------KAQAGKREEDS---QSSSEESDSEEEAPAQAKPSG 431
Query: 161 RAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPG 220
+A V+ ++A +P GA P ++ P A + +QE
Sbjct: 432 KA-------------PQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQE---- 472
Query: 221 GAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAG---R 277
S ++E D+ R+A A + + LG PA+ + G AG
Sbjct: 473 ------EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 278 GRAAADALNRQI----REEVASAVSSSYRNEFRAWTDIKPVKP------IKAKPQYKPPD 327
G+ + Q+ + +S+ SS ++ T + P + ++AKP P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSE--PFKEPPKVEKPSVQ----S 381
+ Q K E KP DN S SE P KP+++
Sbjct: 587 GPPQKAGPVAVQVKAE--KP--MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 382 SKPKKT----SASHKPTR---KAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKL 434
+ PKKT SA P R +A K + A A T +P + S E ++
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS- 701
Query: 435 AEAKESLAQPVSDSSKT----QGPVATEPDKDQ-GSVVPGLLKGQ-GPMVQE--PLKKQG 486
E K LA V + Q A+ P K G +L G+ GP V + K++
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 487 SVVPGPPKDLGPMIPLPV-------KDQDHTVPEPLKNESP--VISAPVKDQGPSVPVPP 537
S D P K Q P + S ISAP K +
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 538 KNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGP 597
++ S + P Q S V P + + V A P +D G S ++
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Query: 598 MVSAPVKDQG----------PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
A VK G P +P KG P P GP + K D
Sbjct: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT---GPSAAQAGKQDDSGSSSEE 938
Query: 648 KDE-----SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDS 696
D +A+ +A + + +P ++ + P + Q P A+ +S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
Score = 38.1 bits (87), Expect = 0.033
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 52/255 (20%)
Query: 214 EQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQT-------------- 259
+QEA P A G+ + K G ++ P + +G G+ Q
Sbjct: 1207 KQEAKPQQAAGMLSPKTGG---KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLL 1263
Query: 260 --PLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPV--- 314
P P +AQVQA+ L + +E V ++ + + W K
Sbjct: 1264 GQPWPLNEAQVQAS---------VVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1314
Query: 315 -KPIKAKPQYKPPD--------DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYS 365
+P P+ K + V S KG+A K A V +++ SL S
Sbjct: 1315 DQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA-KRDKASGDVKEKKGKGSLGS 1373
Query: 366 EPFKEPPKVEKPSVQS-------SKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPST 418
+ K+ P+ E S PK K ++ KDK+ + KKK A+ ST
Sbjct: 1374 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE----KKEKKKKAKKAST 1429
Query: 419 TKPDDKEQSKEMNNK 433
+ Q K+ K
Sbjct: 1430 KDSESPSQKKKKKKK 1444
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.4 bits (150), Expect = 2e-09
Identities = 165/717 (23%), Positives = 248/717 (34%), Gaps = 122/717 (17%)
Query: 22 ADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVAR 81
A + V TK S A + AP + Q + PP+ RA E + E + +
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESE 280
Query: 82 ATGPAPGPTGER--------EPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRP 133
PA + + A+ P + PG G + + G A +V Q K +P
Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQT----KAGKP 335
Query: 134 EPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQAS--APIL 191
E SE + SD+ E ET K L + K Q+ AAS + +P
Sbjct: 336 EEDSESSSE-ESSDS--EEETPAAKAL----LQAKAS----GKTSQVGAASAPAKESPRK 384
Query: 192 GAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRK-AGPAWIVRR 250
GA P +A A RE+++ ++ ++ +E + K +G A VR
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQS------SSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 251 AEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTD 310
A E AA A + TGP AA + +Q + +S+ S E A +
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP-----AAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
Query: 311 IKPVKPIKAKPQYKPPD----------------------------DKMVHETSYSAQFKG 342
VKP+ PQ KP K ++ S++
Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
Query: 343 EASK---PTT---ADNKVIDRRRIRSLYSEPFKEPPKVEKP---SVQSSKPKKTSASHKP 393
++S PT A K + S P K PP+ P V++ KP S S +
Sbjct: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
Query: 394 TRKAKDKQAVSG--QAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKT 451
+ + D + AA+ K A TK K+ + + K+A + P + T
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
Query: 452 QGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-SVVPGPPKDLGPMIPLPVKDQDHT 510
P + P G+ P +K G +V G K +G L VK
Sbjct: 674 -SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK--GLQVK----- 725
Query: 511 VPEPLKNESPVISAPVK---DQGPSVPVPPKNQSPMV----PAKVKDQGSVVPESLKDQG 563
S PVK QG + PV P P V K +D S ES ++
Sbjct: 726 ----------AASVPVKGSLGQG-TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 564 PRIPEPVKN--------------QAPMVPAPVKDEGPMVSAS--VKDQGP-MVSAPVKD- 605
P VK +AP + G +V+A+ K + P V PV++
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 606 QGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQG 662
Q V A P V V + P +D E +E A A +K G
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Score = 57.8 bits (138), Expect = 4e-08
Identities = 141/724 (19%), Positives = 225/724 (31%), Gaps = 172/724 (23%)
Query: 52 QAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSG 111
+ +P++ P +A ++ T+ ++ AR PAPG G+ P G P
Sbjct: 213 EGKPSVKPAQVKASSVSTK------ESPARKAAPAPGKVGDVTPQVKGGALPPAK----- 261
Query: 112 STSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH 171
RA K + S SE + +AP +Q +
Sbjct: 262 --------------RAKKPEEESESSEEGSESE-EEAPAGTRSQVKAS------------ 294
Query: 172 PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKAS 231
K +Q+ AAS AP G P + A PG AG +A+ +
Sbjct: 295 ---EKILQVRAAS---APAKGTPGKGATP----------------APPGKAGAVASQTKA 332
Query: 232 GADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIRE 291
G E D+ + E+TP A Q +A+G + G A+A A +E
Sbjct: 333 GKPEEDSESSS-------EESSDSEEETPAAKALLQAKASGKTSQVGAASAPA-----KE 380
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTAD 351
+ P P K P E S S+ + ++ + A
Sbjct: 381 SPRKGAA--------------PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 352 NKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKK 411
K P + P+V S + + + A+ P RK A +++
Sbjct: 427 AK-------------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 412 SAEGPSTTKPDDKEQSKEMN-------NKLAEAKESLAQPVSDSSKTQGPVAT------- 457
+ S D+E MN K + K + + K GPV
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 458 --------EPDKDQGS--------------VVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
E D + S V P K G ++Q K S GPP+
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ--AKPTSSPAKGPPQK 591
Query: 496 LGPMI-------PLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV 548
GP+ P+ + + +E + P++ +P Q+ P K
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKT 648
Query: 549 KDQGS--VVPESLKDQGPRIPEPVKNQAPMVPA-------PVKDEGPMVSASVKDQGPMV 599
S V P + Q PR + A PA P +D + +++ +
Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGL 708
Query: 600 SAPVKD--------QGPIVPAPVKGE-----GPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
+ V Q PVKG P++P V A K +D E
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-KQEDSESSEE 767
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
D A +P + + S+ K P + P KV +A A ++
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP--GKVVTAAAQAKQRSPS 825
Query: 707 PVVP 710
V P
Sbjct: 826 KVKP 829
Score = 48.9 bits (115), Expect = 2e-05
Identities = 151/714 (21%), Positives = 237/714 (33%), Gaps = 112/714 (15%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P + + + A A+ A G+ V A+ PA + A PG
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDF 160
++GP +A +R E S +S + SD+ E Q +
Sbjct: 393 KTGPAVA------------------KAQAGKREEDS---QSSSEESDSEEEAPAQAKPSG 431
Query: 161 RAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPG 220
+A V+ ++A +P GA P ++ P A + +QE
Sbjct: 432 KA-------------PQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQE---- 472
Query: 221 GAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAG---R 277
S ++E D+ R+A A + + LG PA+ + G AG
Sbjct: 473 ------EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 278 GRAAADALNRQI----REEVASAVSSSYRNEFRAWTDIKPVKP------IKAKPQYKPPD 327
G+ + Q+ + +S+ SS ++ T + P + ++AKP P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSE--PFKEPPKVEKPSVQ----S 381
+ Q K E KP DN S SE P KP+++
Sbjct: 587 GPPQKAGPVAVQVKAE--KP--MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 382 SKPKKT----SASHKPTR---KAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKL 434
+ PKKT SA P R +A K + A A T +P + S E ++
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS- 701
Query: 435 AEAKESLAQPVSDSSKT----QGPVATEPDKDQ-GSVVPGLLKGQ-GPMVQE--PLKKQG 486
E K LA V + Q A+ P K G +L G+ GP V + K++
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 487 SVVPGPPKDLGPMIPLPV-------KDQDHTVPEPLKNESP--VISAPVKDQGPSVPVPP 537
S D P K Q P + S ISAP K +
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 538 KNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGP 597
++ S + P Q S V P + + V A P +D G S ++
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Query: 598 MVSAPVKDQG----------PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
A VK G P +P KG P P GP + K D
Sbjct: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT---GPSAAQAGKQDDSGSSSEE 938
Query: 648 KDE-----SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDS 696
D +A+ +A + + +P ++ + P + Q P A+ +S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
Score = 38.9 bits (89), Expect = 0.019
Identities = 102/457 (22%), Positives = 154/457 (33%), Gaps = 99/457 (21%)
Query: 25 AVPLVFTKYSEATEHPGAPPQPPPPQQQAQ---PALAPPSARAVAIET----QPAQGELD 77
A+ ++ K SEA + P A QP A PA +P S A T +P E+
Sbjct: 1076 ALKVLAQKASEA-QPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ 1134
Query: 78 AVARATGPAPGPTGEREPAAGPGRSGPGP-GLGSGSTSGPADSVMRQDYRAWKVQRPEPS 136
+A + + ++G G GP G S T GP S
Sbjct: 1135 QATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPS----------------- 1177
Query: 137 CRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKR 196
R+E + E + D A P + P A SQAS K
Sbjct: 1178 ---RTETLVEETAAESS---EDDVVA---PSQSLLSGYMTPGLTPANSQAS-------KA 1221
Query: 197 RPQSQERWPVQAAAEARE-----QEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRA 251
P+ V + A++ QEA P A G+ + K G ++ P +
Sbjct: 1222 TPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG---KEAASGTTPQKSRKPK 1278
Query: 252 EGLGHEQT----------------PLPAAQAQVQATGPEAGRGRAAADALNRQIREEVAS 295
+G G+ Q P P +AQVQA+ L + +E
Sbjct: 1279 KGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQAS---------VVKVLTELLEQERKK 1329
Query: 296 AVSSSYRNEFRAWTDIKPV----KPIKAKPQYKPPD--------DKMVHETSYSAQFKGE 343
V ++ + + W K +P P+ K + V S KG+
Sbjct: 1330 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1389
Query: 344 ASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQS-------SKPKKTSASHKPTRK 396
A K A V +++ SL S+ K+ P+ E S PK K ++
Sbjct: 1390 A-KRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1448
Query: 397 AKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNK 433
KDK+ + KKK A+ ST + Q K+ K
Sbjct: 1449 KKDKE----KKEKKKKAKKASTKDSESPSQKKKKKKK 1481
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 62.4 bits (150), Expect = 2e-09
Identities = 165/717 (23%), Positives = 248/717 (34%), Gaps = 122/717 (17%)
Query: 22 ADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVAR 81
A + V TK S A + AP + Q + PP+ RA E + E + +
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESE 280
Query: 82 ATGPAPGPTGER--------EPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRP 133
PA + + A+ P + PG G + + G A +V Q K +P
Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQT----KAGKP 335
Query: 134 EPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQAS--APIL 191
E SE + SD+ E ET K L + K Q+ AAS + +P
Sbjct: 336 EEDSESSSE-ESSDS--EEETPAAKAL----LQAKAS----GKTSQVGAASAPAKESPRK 384
Query: 192 GAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRK-AGPAWIVRR 250
GA P +A A RE+++ ++ ++ +E + K +G A VR
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQS------SSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 251 AEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTD 310
A E AA A + TGP AA + +Q + +S+ S E A +
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP-----AAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
Query: 311 IKPVKPIKAKPQYKPPD----------------------------DKMVHETSYSAQFKG 342
VKP+ PQ KP K ++ S++
Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
Query: 343 EASK---PTT---ADNKVIDRRRIRSLYSEPFKEPPKVEKP---SVQSSKPKKTSASHKP 393
++S PT A K + S P K PP+ P V++ KP S S +
Sbjct: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
Query: 394 TRKAKDKQAVSG--QAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKT 451
+ + D + AA+ K A TK K+ + + K+A + P + T
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
Query: 452 QGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-SVVPGPPKDLGPMIPLPVKDQDHT 510
P + P G+ P +K G +V G K +G L VK
Sbjct: 674 -SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK--GLQVK----- 725
Query: 511 VPEPLKNESPVISAPVK---DQGPSVPVPPKNQSPMV----PAKVKDQGSVVPESLKDQG 563
S PVK QG + PV P P V K +D S ES ++
Sbjct: 726 ----------AASVPVKGSLGQG-TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 564 PRIPEPVKN--------------QAPMVPAPVKDEGPMVSAS--VKDQGP-MVSAPVKD- 605
P VK +AP + G +V+A+ K + P V PV++
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 606 QGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQG 662
Q V A P V V + P +D E +E A A +K G
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Score = 57.8 bits (138), Expect = 4e-08
Identities = 141/724 (19%), Positives = 225/724 (31%), Gaps = 172/724 (23%)
Query: 52 QAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSG 111
+ +P++ P +A ++ T+ ++ AR PAPG G+ P G P
Sbjct: 213 EGKPSVKPAQVKASSVSTK------ESPARKAAPAPGKVGDVTPQVKGGALPPAK----- 261
Query: 112 STSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH 171
RA K + S SE + +AP +Q +
Sbjct: 262 --------------RAKKPEEESESSEEGSESE-EEAPAGTRSQVKAS------------ 294
Query: 172 PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKAS 231
K +Q+ AAS AP G P + A PG AG +A+ +
Sbjct: 295 ---EKILQVRAAS---APAKGTPGKGATP----------------APPGKAGAVASQTKA 332
Query: 232 GADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIRE 291
G E D+ + E+TP A Q +A+G + G A+A A +E
Sbjct: 333 GKPEEDSESSS-------EESSDSEEETPAAKALLQAKASGKTSQVGAASAPA-----KE 380
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTAD 351
+ P P K P E S S+ + ++ + A
Sbjct: 381 SPRKGAA--------------PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 352 NKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKK 411
K P + P+V S + + + A+ P RK A +++
Sbjct: 427 AK-------------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 412 SAEGPSTTKPDDKEQSKEMN-------NKLAEAKESLAQPVSDSSKTQGPVAT------- 457
+ S D+E MN K + K + + K GPV
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 458 --------EPDKDQGS--------------VVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
E D + S V P K G ++Q K S GPP+
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ--AKPTSSPAKGPPQK 591
Query: 496 LGPMI-------PLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV 548
GP+ P+ + + +E + P++ +P Q+ P K
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKT 648
Query: 549 KDQGS--VVPESLKDQGPRIPEPVKNQAPMVPA-------PVKDEGPMVSASVKDQGPMV 599
S V P + Q PR + A PA P +D + +++ +
Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGL 708
Query: 600 SAPVKD--------QGPIVPAPVKGE-----GPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
+ V Q PVKG P++P V A K +D E
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-KQEDSESSEE 767
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
D A +P + + S+ K P + P KV +A A ++
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP--GKVVTAAAQAKQRSPS 825
Query: 707 PVVP 710
V P
Sbjct: 826 KVKP 829
Score = 48.9 bits (115), Expect = 2e-05
Identities = 151/714 (21%), Positives = 237/714 (33%), Gaps = 112/714 (15%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P + + + A A+ A G+ V A+ PA + A PG
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDF 160
++GP +A +R E S +S + SD+ E Q +
Sbjct: 393 KTGPAVA------------------KAQAGKREEDS---QSSSEESDSEEEAPAQAKPSG 431
Query: 161 RAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPG 220
+A V+ ++A +P GA P ++ P A + +QE
Sbjct: 432 KA-------------PQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQE---- 472
Query: 221 GAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAG---R 277
S ++E D+ R+A A + + LG PA+ + G AG
Sbjct: 473 ------EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 278 GRAAADALNRQI----REEVASAVSSSYRNEFRAWTDIKPVKP------IKAKPQYKPPD 327
G+ + Q+ + +S+ SS ++ T + P + ++AKP P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSE--PFKEPPKVEKPSVQ----S 381
+ Q K E KP DN S SE P KP+++
Sbjct: 587 GPPQKAGPVAVQVKAE--KP--MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 382 SKPKKT----SASHKPTR---KAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKL 434
+ PKKT SA P R +A K + A A T +P + S E ++
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS- 701
Query: 435 AEAKESLAQPVSDSSKT----QGPVATEPDKDQ-GSVVPGLLKGQ-GPMVQE--PLKKQG 486
E K LA V + Q A+ P K G +L G+ GP V + K++
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 487 SVVPGPPKDLGPMIPLPV-------KDQDHTVPEPLKNESP--VISAPVKDQGPSVPVPP 537
S D P K Q P + S ISAP K +
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 538 KNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGP 597
++ S + P Q S V P + + V A P +D G S ++
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Query: 598 MVSAPVKDQG----------PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
A VK G P +P KG P P GP + K D
Sbjct: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT---GPSAAQAGKQDDSGSSSEE 938
Query: 648 KDE-----SAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDS 696
D +A+ +A + + +P ++ + P + Q P A+ +S
Sbjct: 939 SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 992
Score = 38.1 bits (87), Expect = 0.033
Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 52/255 (20%)
Query: 214 EQEAAPGGAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQT-------------- 259
+QEA P A G+ + K G ++ P + +G G+ Q
Sbjct: 1206 KQEAKPQQAAGMLSPKTGG---KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLL 1262
Query: 260 --PLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPV--- 314
P P +AQVQA+ L + +E V ++ + + W K
Sbjct: 1263 GQPWPLNEAQVQAS---------VVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG 1313
Query: 315 -KPIKAKPQYKPPD--------DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYS 365
+P P+ K + V S KG+A K A V +++ SL S
Sbjct: 1314 DQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKA-KRDKASGDVKEKKGKGSLGS 1372
Query: 366 EPFKEPPKVEKPSVQS-------SKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPST 418
+ K+ P+ E S PK K ++ KDK+ + KKK A+ ST
Sbjct: 1373 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE----KKEKKKKAKKAST 1428
Query: 419 TKPDDKEQSKEMNNK 433
+ Q K+ K
Sbjct: 1429 KDSESPSQKKKKKKK 1443
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 62.4 bits (150), Expect = 2e-09
Identities = 165/717 (23%), Positives = 248/717 (34%), Gaps = 122/717 (17%)
Query: 22 ADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVAR 81
A + V TK S A + AP + Q + PP+ RA E + E + +
Sbjct: 221 AQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESE 280
Query: 82 ATGPAPGPTGER--------EPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRP 133
PA + + A+ P + PG G + + G A +V Q K +P
Sbjct: 281 EEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG-ATPAPPGKAGAVASQT----KAGKP 335
Query: 134 EPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQAS--APIL 191
E SE + SD+ E ET K L + K Q+ AAS + +P
Sbjct: 336 EEDSESSSE-ESSDS--EEETPAAKAL----LQAKAS----GKTSQVGAASAPAKESPRK 384
Query: 192 GAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKASGADERDTRRK-AGPAWIVRR 250
GA P +A A RE+++ ++ ++ +E + K +G A VR
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQS------SSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 251 AEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTD 310
A E AA A + TGP AA + +Q + +S+ S E A +
Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGP-----AAAQVQVGKQEEDSRSSSEESDSDREALAAMN 493
Query: 311 IKPVKPIKAKPQYKPPD----------------------------DKMVHETSYSAQFKG 342
VKP+ PQ KP K ++ S++
Sbjct: 494 AAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESS 553
Query: 343 EASK---PTT---ADNKVIDRRRIRSLYSEPFKEPPKVEKP---SVQSSKPKKTSASHKP 393
++S PT A K + S P K PP+ P V++ KP S S +
Sbjct: 554 DSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 613
Query: 394 TRKAKDKQAVSG--QAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVSDSSKT 451
+ + D + AA+ K A TK K+ + + K+A + P + T
Sbjct: 614 SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673
Query: 452 QGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQG-SVVPGPPKDLGPMIPLPVKDQDHT 510
P + P G+ P +K G +V G K +G L VK
Sbjct: 674 -SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGK--GLQVK----- 725
Query: 511 VPEPLKNESPVISAPVK---DQGPSVPVPPKNQSPMV----PAKVKDQGSVVPESLKDQG 563
S PVK QG + PV P P V K +D S ES ++
Sbjct: 726 ----------AASVPVKGSLGQG-TAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774
Query: 564 PRIPEPVKN--------------QAPMVPAPVKDEGPMVSAS--VKDQGP-MVSAPVKD- 605
P VK +AP + G +V+A+ K + P V PV++
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNP 834
Query: 606 QGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQG 662
Q V A P V V + P +D E +E A A +K G
Sbjct: 835 QNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSG 891
Score = 57.8 bits (138), Expect = 4e-08
Identities = 141/724 (19%), Positives = 225/724 (31%), Gaps = 172/724 (23%)
Query: 52 QAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSG 111
+ +P++ P +A ++ T+ ++ AR PAPG G+ P G P
Sbjct: 213 EGKPSVKPAQVKASSVSTK------ESPARKAAPAPGKVGDVTPQVKGGALPPAK----- 261
Query: 112 STSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH 171
RA K + S SE + +AP +Q +
Sbjct: 262 --------------RAKKPEEESESSEEGSESE-EEAPAGTRSQVKAS------------ 294
Query: 172 PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGAGGLAAGKAS 231
K +Q+ AAS AP G P + A PG AG +A+ +
Sbjct: 295 ---EKILQVRAAS---APAKGTPGKGATP----------------APPGKAGAVASQTKA 332
Query: 232 GADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGRGRAAADALNRQIRE 291
G E D+ + E+TP A Q +A+G + G A+A A +E
Sbjct: 333 GKPEEDSESSS-------EESSDSEEETPAAKALLQAKASGKTSQVGAASAPA-----KE 380
Query: 292 EVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTAD 351
+ P P K P E S S+ + ++ + A
Sbjct: 381 SPRKGAA--------------PAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 352 NKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKK 411
K P + P+V S + + + A+ P RK A +++
Sbjct: 427 AK-------------PSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 412 SAEGPSTTKPDDKEQSKEMN-------NKLAEAKESLAQPVSDSSKTQGPVAT------- 457
+ S D+E MN K + K + + K GPV
Sbjct: 474 DSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT 533
Query: 458 --------EPDKDQGS--------------VVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
E D + S V P K G ++Q K S GPP+
Sbjct: 534 PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ--AKPTSSPAKGPPQK 591
Query: 496 LGPMI-------PLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKV 548
GP+ P+ + + +E + P++ +P Q+ P K
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP---QTKACPKKT 648
Query: 549 KDQGS--VVPESLKDQGPRIPEPVKNQAPMVPA-------PVKDEGPMVSASVKDQGPMV 599
S V P + Q PR + A PA P +D + +++ +
Sbjct: 649 NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGL 708
Query: 600 SAPVKD--------QGPIVPAPVKGE-----GPIVPAPVKDEGPMVSAPIKDQDPMVPEH 646
+ V Q PVKG P++P V A K +D E
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE-KQEDSESSEE 767
Query: 647 PKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQG 706
D A +P + + S+ K P + P KV +A A ++
Sbjct: 768 ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP--GKVVTAAAQAKQRSPS 825
Query: 707 PVVP 710
V P
Sbjct: 826 KVKP 829
Score = 47.0 bits (110), Expect = 7e-05
Identities = 145/671 (21%), Positives = 220/671 (32%), Gaps = 107/671 (15%)
Query: 41 GAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPAAGPG 100
G P + + + A A+ A G+ V A+ PA + A PG
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
Query: 101 RSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDF 160
++GP +A +R E S +S + SD+ E Q +
Sbjct: 393 KTGPAVA------------------KAQAGKREEDS---QSSSEESDSEEEAPAQAKPSG 431
Query: 161 RAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPG 220
+A V+ ++A +P GA P ++ P A + +QE
Sbjct: 432 KA-------------PQVRAASAPAKESPRKGAAPAPP--RKTGPAAAQVQVGKQE---- 472
Query: 221 GAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAG---R 277
S ++E D+ R+A A + + LG PA+ + G AG
Sbjct: 473 ------EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 278 GRAAADALNRQI----REEVASAVSSSYRNEFRAWTDIKPVKP------IKAKPQYKPPD 327
G+ + Q+ + +S+ SS ++ T + P + ++AKP P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 328 DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSE--PFKEPPKVEKPSVQ----S 381
+ Q K E KP DN S SE P KP+++
Sbjct: 587 GPPQKAGPVAVQVKAE--KP--MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 382 SKPKKT----SASHKPTR---KAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKL 434
+ PKKT SA P R +A K + A A T +P + S E ++
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDS- 701
Query: 435 AEAKESLAQPVSDSSKT----QGPVATEPDKDQ-GSVVPGLLKGQ-GPMVQE--PLKKQG 486
E K LA V + Q A+ P K G +L G+ GP V + K++
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQED 761
Query: 487 SVVPGPPKDLGPMIPLPV-------KDQDHTVPEPLKNESP--VISAPVKDQGPSVPVPP 537
S D P K Q P + S ISAP K +
Sbjct: 762 SESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQ 821
Query: 538 KNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGP 597
++ S + P Q S V P + + V A P +D G S ++
Sbjct: 822 RSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEA 881
Query: 598 MVSAPVKDQG----------PIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
A VK G P +P KG P P GP + K D
Sbjct: 882 ETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT---GPSAAQAGKQDDSGSSSEE 938
Query: 648 KDESAMATAPI 658
D A A +
Sbjct: 939 SDSDGEAPAAV 949
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 62.4 bits (150), Expect = 2e-09
Identities = 107/496 (21%), Positives = 184/496 (37%), Gaps = 75/496 (15%)
Query: 374 VEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAE--GPSTTKPDDKEQSKEMN 431
+ +P S+K K+ + HK + K + Q A + E + ++ +++K+
Sbjct: 167 ISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETKKGP 226
Query: 432 NKLAE--AKESLAQPV-SDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSV 488
L E +E + PV + S + + E + P K Q P+V+E K
Sbjct: 227 PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPA--KIQPPLVEEATAKAE-- 282
Query: 489 VPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAP--VKDQGPSVPVPPKNQSPMV-- 544
P P ++ H +P E+P A V + V PP ++P+V
Sbjct: 283 ------------PRPA-EETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEF 329
Query: 545 PAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMV--SASVKDQGPMVSAP 602
PA+++ + S++ +P P ++P P + P S SV+ G + +P
Sbjct: 330 PAEIQPPSAEESPSVELLAEILP-PSAEESPSEEPPAEILPPPAEKSPSVELLGE-IRSP 387
Query: 603 VKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEH-PKDE-------SAMA 654
+ PI P+ EG + AP K E P V + D P++PE P++E +AM
Sbjct: 388 SAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAME 447
Query: 655 T----APIKNQGSMVSE------------------PVKNQGLVVSGPVKDQDVVVPEHAK 692
T AP + Q + E P P+ ++ HA+
Sbjct: 448 TPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAE 507
Query: 693 VHD------SAVVAPVKNQ------GPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGR 740
V +A A + Q P + Q P+ ++ P +Q P +G
Sbjct: 508 VQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGV 567
Query: 741 IVPE-PLKNQVPI-VPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPT-VSPLPR 797
+ E PL+ Q P ++ + + A + A P + Q P + P V P P
Sbjct: 568 SIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPA 627
Query: 798 VMIPTAPHTEYIESSP 813
P E +P
Sbjct: 628 EEAPAEVQPPPAEEAP 643
Score = 54.7 bits (130), Expect = 3e-07
Identities = 96/508 (18%), Positives = 181/508 (35%), Gaps = 77/508 (15%)
Query: 339 QFKGEASKPTTADNKVIDRRRIRSLYSEP---FKEPPKVEKPSVQSS----KPKKTSASH 391
+ + E + P + + +++ S EP K P K++ P V+ + +P+ +H
Sbjct: 233 ELREEVTVPVVQEGSAV--KKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETH 290
Query: 392 ----KPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKES------L 441
T + D +A + A + P + E E+ AE S +
Sbjct: 291 VQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEI 350
Query: 442 AQPVSDSSKTQGPVAT--EPDKDQGSVVPGLLKGQGPMVQ------EPLKKQGSVVPGPP 493
P ++ S ++ P A P ++ V L + + P Q +PL +G++ P
Sbjct: 351 LPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPA 410
Query: 494 KDLGPMIPLPVKDQDHTVPEPL-KNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQG 552
K P + + D +PE + E+ + + P+ P + QSP+ ++
Sbjct: 411 KVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEA 470
Query: 553 SVVPESLKDQGPRIPE-PVKNQAPM------------VPAPVKDEGPMVSASVKDQG-PM 598
S + L P E P + ++P+ V +P+ +E AS + Q
Sbjct: 471 SAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAA 530
Query: 599 VSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPI 658
+ AP + +P+ E AP + + P ++ P+ + P E A
Sbjct: 531 IEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA---- 586
Query: 659 KNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDP 718
++ + A SA AP + Q P E+ P
Sbjct: 587 ----------------------EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQP 624
Query: 719 ILPVLVKDQGPTVLQPPKNQ---GRIVPEPLKN-QVPIVPVPLKDQDPLVPVPAKDQGPA 774
++ P +QPP + + P P + + P P ++ V P ++ PA
Sbjct: 625 ----PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 680
Query: 775 VPEPLKT-QGPRDPQLPTVSPLPRVMIP 801
+ L + P + L V P +P
Sbjct: 681 EVQSLPAEETPIEETLAAVHSPPADDVP 708
Score = 52.0 bits (123), Expect = 2e-06
Identities = 100/511 (19%), Positives = 177/511 (34%), Gaps = 45/511 (8%)
Query: 161 RAWPLPRRGDHPWI-PKPVQISAASQASAPILGAPKRRPQSQERWP-VQAAAEAREQEAA 218
+A P P H + P + A A+A + K +P E P V+ AE + A
Sbjct: 280 KAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAE 339
Query: 219 PGGAGGLAA------GKASGADERDTRRKAGPAWIVRRAEGLGHEQTP-LPAAQAQVQAT 271
+ L A + S ++E PA E LG ++P A +VQ
Sbjct: 340 ESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPL 399
Query: 272 GPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKA-KPQYKPPDDKM 330
E A A + E +A D++P+ P +A + + +
Sbjct: 400 PAEGALEEAPAKVEPPTVEETLA---------------DVQPLLPEEAPREEARELQLST 444
Query: 331 VHETSYS---AQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKT 387
ET +F+ K TTA+ + + + + + P + P + + ++
Sbjct: 445 AMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA 504
Query: 388 SAS-HKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAEAKESLAQPVS 446
A P + + S + + E P+ P + + EA + P +
Sbjct: 505 HAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSA 564
Query: 447 DSS-------KTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGP- 498
+ Q P E ++ S LL +E + V PP + P
Sbjct: 565 KGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE----VQPPPAEEAPA 620
Query: 499 -MIPLPVKDQDHTVPEPLKNESPV-ISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVP 556
+ P P ++ V P E+P + P ++ P+ PP + PA+V+ +
Sbjct: 621 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE--APAEVQPPPAEEA 678
Query: 557 ESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKG 616
+ P P++ V +P D+ P ASV P + ++ PI A +
Sbjct: 679 PAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEV 738
Query: 617 EGPIVPAPVKDEGPMVSAPIKDQDPMVPEHP 647
P +DE + + + Q P V P
Sbjct: 739 SPPPSEQTPEDEALVENVSTEFQSPQVAGIP 769
Score = 33.5 bits (75), Expect = 0.81
Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 4/99 (4%)
Query: 20 DKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAV 79
++A A+ L+ + A E P PPP ++A + PP A E QP E +A
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEVQ--PPPAEEAPAEVQPPPAEEAPAEVQPPPAE-EAP 643
Query: 80 ARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPAD 118
A P P E P P + PA+
Sbjct: 644 AEVQ-PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE 681
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 60.5 bits (145), Expect = 6e-09
Identities = 144/628 (22%), Positives = 206/628 (32%), Gaps = 95/628 (15%)
Query: 37 TEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGPTGEREPA 96
T P P+PPPP PA A A+ +P + AT P E P
Sbjct: 26 TPRPPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGIGGATIP------ESAPR 76
Query: 97 AGPGRSGPGPGLGSGSTSGPADSV----MRQDYRAWKVQRPEPSCRPRSEYQPSDAPFE- 151
AGP R+ P G G + PA + + RA RP P + +
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 152 RETQYQKDFRAWPLPRR---GDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWP--- 205
+ T+ K RR G P P P ++ S+A+ +G P+ P ++ R P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEG 195
Query: 206 ----VQAAAEAREQEAAPG-----GAGGLAAGKASGADERDTRRKAGPAWIVRRAEGLGH 256
V +A+E E +P AGG AS + + PA A G
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG--- 252
Query: 257 EQTP-LPAAQAQVQATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVK 315
TP PA +Q + G +A R R++ A A+ + + P
Sbjct: 253 --TPRAPAHPSQPKPKGLQALRPPQVTPP-----RKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 316 PIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVE 375
P A P + S + G S A + + + L + P + PP +
Sbjct: 306 P-SAPPSLQTLPSPPATPPSQATTSLG--SPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 376 KPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLA 435
P +Q+ S P QA + A A P + P Q A
Sbjct: 363 LPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQA--PFSPPPSPPVQ--------A 411
Query: 436 EAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKD 495
+ PVS P AT P + S+ P +Q P S P
Sbjct: 412 PFSPPASPPVS-------PSATPPSQAPPSLA-------APPLQVPPSPPASPPMSPSAT 457
Query: 496 LGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVV 555
P P P+ PL+ P AP P++ PP P PA Q
Sbjct: 458 PPPQAPPPL------AAPPLQLAKPPPQAP-----PALATPPLQALPSPPASFPGQAPFS 506
Query: 556 PESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVK 615
P + P + P P++ AP+ P AS P + AP + P V
Sbjct: 507 PSASLPMSP-LATPPPQAPPVLAAPLLQVPPSPPAS-----PTLQAPRRPPTPGPDTSVS 560
Query: 616 G--------EGPIVPAPVKDEGPMVSAP 635
G GP P P + +S P
Sbjct: 561 GPRLTLALAPGP-PPPPSRSPSSTLSGP 587
Score = 44.3 bits (103), Expect = 5e-04
Identities = 97/464 (20%), Positives = 158/464 (34%), Gaps = 78/464 (16%)
Query: 377 PSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDDKEQSKEMNNKLAE 436
P ++ + AS + R K G + A G TT+P Q
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG--TTRPGPLGQK----GLRIS 128
Query: 437 AKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVV--PGPPK 494
A+E++A+ + + + ++ +D PG P + + G+ V P P
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGT---PSPAMARRSRAAGTEVGLPRPAP 185
Query: 495 DLGPMIPL--PVKD----QDHTVPEP---------------------LKNESPVISAPVK 527
P P P K +H+ EP L + + +S+P +
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 528 DQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPM 587
GPS P+ +P P++ K +G ++L+ P++ P K+ AP + GP+
Sbjct: 246 S-GPSARGTPR--APAHPSQPKPKGL---QALRP--PQVTPPRKDAAPAL-------GPL 290
Query: 588 VSASVKDQGPMVSAPVKDQGP--IVPAPVKGEGPIVPAPVKDEGPMVSA-----PIKDQD 640
S+ + P SAP P + P P A P + A P
Sbjct: 291 SSSPLATPSP--SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 641 PMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAVVA 700
P+ P+ A+A P++ S + P + P+ P VH + A
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLS-------PLATPSPQAPNALAVH--LLQA 399
Query: 701 PVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQ 760
P P S Q P P P+ P + + PL QVP P
Sbjct: 400 PFSP-----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPM 452
Query: 761 DPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAP 804
P P + P PL+ P P ++ P +P+ P
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Score = 41.2 bits (95), Expect = 0.004
Identities = 87/398 (21%), Positives = 125/398 (31%), Gaps = 61/398 (15%)
Query: 445 VSDSSKTQGPVATE--PDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPL 502
+ +S+ GP T P +G P V P + G+ PGP G I
Sbjct: 70 IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI-- 127
Query: 503 PVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVP-PKNQSPMVPAKVKDQGSVV--PESL 559
+ TV E+P SA P P SP + + + G+ V P
Sbjct: 128 ---SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 560 KDQGPRIP--------EPVKNQAPMVPAPVKDEGPMV--------SASVKDQGPMVSAPV 603
PR P + P+P P S S+ +S+P
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244
Query: 604 KD--------QGPIVPAPVKGEG------PIVPAPVKDE----GPMVSAPIKDQDPMVPE 645
+ + P P+ K +G P V P KD GP+ S+P+ P P
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304
Query: 646 HPKDESAM-------ATAPIKNQGSMVSEPVKNQGLVVSGPVKDQDVVVPEHAKVHDSAV 698
P ++ AT P + S+ S ++ + P P A A+
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA---PPAL 361
Query: 699 VAPVKNQGPVVPESVKNQDPILPVLV-KDQGPTVLQPPKNQGRIVPEPLKN-QVPIVPVP 756
P P P S P+ P+ Q P L Q P P Q P P
Sbjct: 362 ALPPLQAPPSPPAS----PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417
Query: 757 LKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSP 794
P P++ PL+ P P P +SP
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSP 454
Score = 36.2 bits (82), Expect = 0.13
Identities = 40/176 (22%), Positives = 57/176 (32%), Gaps = 17/176 (9%)
Query: 24 IAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARAT 83
+AV L+ +S P P PP P+ PPS ++ P Q
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ---------V 442
Query: 84 GPAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEY 143
P+P + P+A P P P + P + P P
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPP-----LAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 144 Q-PSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRP 198
P APF A P P+ P + P+ S ++P L AP+R P
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQA--PPVLAAPLLQVPPSPPASPTLQAPRRPP 551
Score = 31.2 bits (69), Expect = 4.0
Identities = 45/184 (24%), Positives = 58/184 (31%), Gaps = 22/184 (11%)
Query: 36 ATEHPGAPPQPPPP---QQQAQPALAPPSARAVAIETQPAQG--------ELDAVARATG 84
AT P APP P P Q P PPS ++ + Q L +A
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 85 PAPGPTGEREPAAGPGRSGPGPGLGSGSTSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQ 144
AP P P P P L +T P + P PS
Sbjct: 356 QAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-------P 407
Query: 145 PSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERW 204
P APF A P P + P+Q+ + AS P+ +P P Q
Sbjct: 408 PVQAPFSPPASPPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPM--SPSATPPPQAPP 464
Query: 205 PVQA 208
P+ A
Sbjct: 465 PLAA 468
Score = 31.2 bits (69), Expect = 4.0
Identities = 68/281 (24%), Positives = 93/281 (33%), Gaps = 56/281 (19%)
Query: 36 ATEHPGAPPQ------PPPPQQQAQPALAPPSARAVAIETQPAQGELDAVARATGPAPGP 89
AT P APP PP A P L P G +A A GP P P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 90 TGEREPAA---GPGRSG----------------PGPGLGSGSTSGPADSVMRQDYRAWKV 130
+ R P++ GP +G GP G + S P D+ + + A
Sbjct: 577 S--RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE-GGAAASPPPDAELAACHPAAWS 633
Query: 131 QRPEPSCRPRSE------YQPSDAPFERE---TQYQKDFRAWPLPRRGDHPWIPKPVQIS 181
+ P P R + P+ P + T Y+ + P G P P S
Sbjct: 634 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP-GTS 692
Query: 182 AASQASAPILGAPKRRPQSQE--RWPVQAAAEAREQ------------EAAPGGAGGLAA 227
A+ GA R P+ P+ A + Q E A GG+GG
Sbjct: 693 GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG 752
Query: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQV 268
G G R A + R AE L +PL ++A +
Sbjct: 753 GAEGGGVTGGARAALSDAELGRWAELL----SPLDESRASI 789
>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 60.1 bits (144), Expect = 8e-09
Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%)
Query: 16 WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73
W +L P + + PG PQP Q +P + PP V + P +
Sbjct: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
Query: 74 GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117
L A ARA G P+P E PA+ SG PGP G GS
Sbjct: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191
Query: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171
+ + + R PE P CR S P + +K R PLPR
Sbjct: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
Query: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227
P S++ A P +P R P + P A E R +P A GG ++
Sbjct: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308
Query: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
G SG D + A PA A G P + + A GP + R
Sbjct: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358
>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 60.1 bits (144), Expect = 8e-09
Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%)
Query: 16 WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73
W +L P + + PG PQP Q +P + PP V + P +
Sbjct: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
Query: 74 GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117
L A ARA G P+P E PA+ SG PGP G GS
Sbjct: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191
Query: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171
+ + + R PE P CR S P + +K R PLPR
Sbjct: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
Query: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227
P S++ A P +P R P + P A E R +P A GG ++
Sbjct: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308
Query: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
G SG D + A PA A G P + + A GP + R
Sbjct: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358
>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 60.1 bits (144), Expect = 8e-09
Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%)
Query: 16 WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73
W +L P + + PG PQP Q +P + PP V + P +
Sbjct: 74 WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
Query: 74 GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117
L A ARA G P+P E PA+ SG PGP G GS
Sbjct: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191
Query: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171
+ + + R PE P CR S P + +K R PLPR
Sbjct: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
Query: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227
P S++ A P +P R P + P A E R +P A GG ++
Sbjct: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308
Query: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277
G SG D + A PA A G P + + A GP + R
Sbjct: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,890,004
Number of Sequences: 37866
Number of extensions: 2766076
Number of successful extensions: 28234
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 245
Number of HSP's successfully gapped in prelim test: 1590
Number of HSP's that attempted gapping in prelim test: 16063
Number of HSP's gapped (non-prelim): 10603
length of query: 813
length of database: 18,247,518
effective HSP length: 111
effective length of query: 702
effective length of database: 14,044,392
effective search space: 9859163184
effective search space used: 9859163184
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.