Search of human proteins with 4826876

Search of human proteins with 4826876

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826876 osteomodulin [Homo sapiens]
         (421 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826876 osteomodulin [Homo sapiens]                                885   0.0  
gi|5901992 keratocan [Homo sapiens]                                   257   1e-68
gi|41349454 proline arginine-rich end leucine-rich repeat protei...   248   7e-66
gi|4506041 proline arginine-rich end leucine-rich repeat protein...   248   7e-66
gi|4505047 lumican precursor [Homo sapiens]                           236   2e-62
gi|71040111 fibromodulin precursor [Homo sapiens]                     225   5e-59
gi|41350214 asporin [Homo sapiens]                                    139   6e-33
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...   122   6e-28
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...   122   6e-28
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]    120   2e-27
gi|19743846 decorin isoform a preproprotein [Homo sapiens]            112   8e-25
gi|4503271 decorin isoform a preproprotein [Homo sapiens]             112   8e-25
gi|45505137 podocan [Homo sapiens]                                    110   2e-24
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...   108   1e-23
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                  103   2e-22
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                  103   2e-22
gi|4502403 biglycan preproprotein [Homo sapiens]                      102   9e-22
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom...   101   1e-21
gi|153251229 chondroadherin precursor [Homo sapiens]                   97   2e-20
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                   96   5e-20
gi|20302168 toll-like receptor 8 [Homo sapiens]                        96   5e-20
gi|51317373 netrin-G1 ligand [Homo sapiens]                            92   9e-19
gi|88702793 slit-like 2 [Homo sapiens]                                 92   9e-19
gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo...    89   6e-18
gi|225579152 insulin-like growth factor binding protein, acid la...    89   7e-18
gi|4826772 insulin-like growth factor binding protein, acid labi...    89   7e-18
gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo sapi...    89   7e-18
gi|7657419 opticin precursor [Homo sapiens]                            89   7e-18
gi|122937309 leucine rich repeat containing 4B [Homo sapiens]          88   2e-17
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s...    86   8e-17

>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score =  885 bits (2287), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 1   MGFLSPIYVIFFFFGVKVHCQYETYQWDEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTL 60
           MGFLSPIYVIFFFFGVKVHCQYETYQWDEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTL
Sbjct: 1   MGFLSPIYVIFFFFGVKVHCQYETYQWDEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTL 60

Query: 61  GCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           GCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEI
Sbjct: 61  GCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
           NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN
Sbjct: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
           AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL
Sbjct: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPR 300
           ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPR
Sbjct: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPR 300

Query: 301 NLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTI 360
           NLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTI
Sbjct: 301 NLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTI 360

Query: 361 YYGEQRSTNGQTIQLKTQVFRRFPDDDDESEDHDDPDNAHESPEQEGAEGHFDLHYYENQ 420
           YYGEQRSTNGQTIQLKTQVFRRFPDDDDESEDHDDPDNAHESPEQEGAEGHFDLHYYENQ
Sbjct: 361 YYGEQRSTNGQTIQLKTQVFRRFPDDDDESEDHDDPDNAHESPEQEGAEGHFDLHYYENQ 420

Query: 421 E 421
           E
Sbjct: 421 E 421


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score =  257 bits (657), Expect = 1e-68
 Identities = 135/303 (44%), Positives = 193/303 (63%), Gaps = 10/303 (3%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121
           C  ECFCP +FP+++YC+NR LK IP IP  I  LYLQ N IE +    F NAT L+ IN
Sbjct: 42  CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101

Query: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNA 181
           L+ NKI +  I+ G  ++L  LL L LE N LEE P PLP+SLE+L L  N++S++    
Sbjct: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 161

Query: 182 MDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLE 241
              L NLT+LDL  N L D+  +   F  ++ LMQLN+  N L +MPP LP++ M L L+
Sbjct: 162 FSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 221

Query: 242 NNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIP 299
           NNSI  IPE YF+ +PK+  LR++HNKL D  +P   F++ +I++L + HN+L +   I 
Sbjct: 222 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRIS 281

Query: 300 RNLEHLYLQNNEIEKMNLTVMCPSIDPL--------HYHHLTYIRVDQNKLKEPISSYIF 351
            +L+HL+L +N+I+ +N++V+CPS   L        +  HL Y+R+D N++K PI   + 
Sbjct: 282 AHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALM 341

Query: 352 FCF 354
            CF
Sbjct: 342 TCF 344


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  248 bits (633), Expect = 7e-66
 Identities = 134/311 (43%), Positives = 188/311 (60%), Gaps = 15/311 (4%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121
           C  EC+CP +FPS++YCD+R L+ +P IP  I  LYLQ N I  +   SF NAT L+ IN
Sbjct: 73  CPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWIN 132

Query: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNA 181
           L +N+I+  KID  V  KLP L+ L++E N LEE P  LP++LE+L L  N IS++    
Sbjct: 133 LDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGV 190

Query: 182 MDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLE 241
              L NL +LDL +N L D + K   F  ++ LMQLNL  N L  MPP +P+++  L L+
Sbjct: 191 FSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLD 250

Query: 242 NNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIP 299
           +N I +IP  YF   P L  +R+++NKL D  +P N FN+ N++ L + HN++     I 
Sbjct: 251 SNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAIN 310

Query: 300 RNLEHLYLQNNEIEKMNLTVMCPSIDPLHYH----------HLTYIRVDQNKLKEPISSY 349
             LEHLYL NN IEK+N T +CP+ D + +H          HL Y+R+D N LK PI   
Sbjct: 311 NRLEHLYLNNNSIEKINGTQICPN-DLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369

Query: 350 IFFCFPHIHTI 360
           +  CF  + ++
Sbjct: 370 LMMCFRLLQSV 380


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  248 bits (633), Expect = 7e-66
 Identities = 134/311 (43%), Positives = 188/311 (60%), Gaps = 15/311 (4%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121
           C  EC+CP +FPS++YCD+R L+ +P IP  I  LYLQ N I  +   SF NAT L+ IN
Sbjct: 73  CPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWIN 132

Query: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNA 181
           L +N+I+  KID  V  KLP L+ L++E N LEE P  LP++LE+L L  N IS++    
Sbjct: 133 LDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGV 190

Query: 182 MDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLE 241
              L NL +LDL +N L D + K   F  ++ LMQLNL  N L  MPP +P+++  L L+
Sbjct: 191 FSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLD 250

Query: 242 NNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIP 299
           +N I +IP  YF   P L  +R+++NKL D  +P N FN+ N++ L + HN++     I 
Sbjct: 251 SNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAIN 310

Query: 300 RNLEHLYLQNNEIEKMNLTVMCPSIDPLHYH----------HLTYIRVDQNKLKEPISSY 349
             LEHLYL NN IEK+N T +CP+ D + +H          HL Y+R+D N LK PI   
Sbjct: 311 NRLEHLYLNNNSIEKINGTQICPN-DLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369

Query: 350 IFFCFPHIHTI 360
           +  CF  + ++
Sbjct: 370 LMMCFRLLQSV 380


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score =  236 bits (603), Expect = 2e-62
 Identities = 127/303 (41%), Positives = 191/303 (63%), Gaps = 8/303 (2%)

Query: 47  QNVDYGVP---FHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEI 103
           Q  DY  P   + Q +  C  EC CP ++PS+MYCD  KLK++P +P  I+ LYL+ N+I
Sbjct: 19  QYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQI 78

Query: 104 EAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKS 163
           + +   +F N T L+ + L HN +++ KI   VF+KL  L +LH+ HNNL E   PLPKS
Sbjct: 79  DHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKS 138

Query: 164 LERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNR 223
           LE L L +N+I+KL   + +GLVNLT + L +N L +  +    F  ++ L  L+L  N+
Sbjct: 139 LEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQ 195

Query: 224 LESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPN 281
           +  +P GLP SL+ L L+NN IS+IP++YF +   L  LR+SHN+L D  IP N FN+ +
Sbjct: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSS 255

Query: 282 IVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNK 341
           +VEL + +NKLK    +  NLE+ YL+ N++EK ++   C  + PL Y  + ++R+D N+
Sbjct: 256 LVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNR 315

Query: 342 LKE 344
           + E
Sbjct: 316 ISE 318



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 44/187 (23%), Positives = 85/187 (45%), Gaps = 41/187 (21%)

Query: 223 RLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFN-L 279
           +L+S+P  +P  + YL L NN I  I EK F+ +  L  L + HN L++  I   +F+ L
Sbjct: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115

Query: 280 PNIVELSVGHNKLKQAFY-IPRNLEHL----------------------YLQNNEIEKMN 316
             + +L + HN L ++   +P++LE L                      +LQ+N +++  
Sbjct: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDA 175

Query: 317 LTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIYYGEQRSTNGQTIQLK 376
           ++     +  L Y  L++ ++ +     P+S         + T+Y    + +N     + 
Sbjct: 176 VSAAFKGLKSLEYLDLSFNQIARLPSGLPVS---------LLTLYLDNNKISN-----IP 221

Query: 377 TQVFRRF 383
            + F+RF
Sbjct: 222 DEYFKRF 228


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score =  225 bits (574), Expect = 5e-59
 Identities = 127/331 (38%), Positives = 195/331 (58%), Gaps = 16/331 (4%)

Query: 21  QYETYQWDEDYDQEPDDDYQTGFPFRQNVD------YGVPFHQYTLGCVSECFCPTNFPS 74
           Q  TY   + YD  P   Y+T  P+   VD      YG P       C  EC CP NFP+
Sbjct: 34  QQSTYY--DPYDPYP---YETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPT 88

Query: 75  SMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDY 134
           +MYCDNR LK +P +P  ++ +Y Q N+I ++    F NAT L  I L  N+I S K+  
Sbjct: 89  AMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148

Query: 135 GVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
            VF+KL +L +L+L+HNNL   P PLP+SL  L L +N+IS++  NA++GL NLT L L 
Sbjct: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQ 208

Query: 195 YNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFD 254
           +N + +          +  L+ L+L  N L  +P GLPS+L  L +E+N++ ++P+ YF 
Sbjct: 209 HNEIQE---VGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFR 265

Query: 255 KLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEI 312
             PKL  +R+SHN L +  +  N FN  +++EL + +N+L++   +  NLE+LYLQ N I
Sbjct: 266 GAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRI 325

Query: 313 EKMNLTVMCPSIDPLHYHHLTYIRVDQNKLK 343
            + +++  C  +D +++  L  +R+D N++K
Sbjct: 326 NEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score =  139 bits (349), Expect = 6e-33
 Identities = 95/324 (29%), Positives = 168/324 (51%), Gaps = 18/324 (5%)

Query: 28  DEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIP 87
           D+D D + DD+  + FP R+   +  PF  + + C   C C   +   ++C +  L ++P
Sbjct: 42  DDDDDDDDDDEDNSLFPTREPRSHFFPFDLFPM-CPFGCQC---YSRVVHCSDLGLTSVP 97

Query: 88  -NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQL 146
            NIP   + L LQ N+I+ +  N F   T L  + L++NK+   KI    F     L +L
Sbjct: 98  TNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHPKAFLTTKKLRRL 155

Query: 147 HLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDK 206
           +L HN L E P  LPKSL  L +  N++ K+Q +   G+  L +L++  N L ++ ++  
Sbjct: 156 YLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPG 215

Query: 207 IFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSH 266
            F  +  +  + +   +L S+P GLP +L+ L L+ N IS++  + F +  +L  L + +
Sbjct: 216 AFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGN 274

Query: 267 NKLQDIPY-NIFNLPNIVELSVGHNKLKQAFYIPRNLEHL------YLQNNEIEKMNLTV 319
           NK+ DI   ++ N+P + E+ + +NKLK+   IP  L  L      +L +N I ++ +  
Sbjct: 275 NKITDIENGSLANIPRVREIHLENNKLKK---IPSGLPELKYLQIIFLHSNSIARVGVND 331

Query: 320 MCPSIDPLHYHHLTYIRVDQNKLK 343
            CP++  +     + I +  N +K
Sbjct: 332 FCPTVPKMKKSLYSAISLFNNPVK 355


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  122 bits (306), Expect = 6e-28
 Identities = 81/258 (31%), Positives = 134/258 (51%), Gaps = 12/258 (4%)

Query: 45  FRQNVDYGVPFHQYTLGCVSECFCPTNFPSSM---------YCDNRKLKTIP-NIPMHIQ 94
           F  ++  G+P    TL   +        PS +         Y  +  L   P N+P +++
Sbjct: 48  FLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVK 107

Query: 95  QLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE 154
           +L+LQ N I  +T +S     +L+E++L  N + +  I+ G F     L  L L  N+L 
Sbjct: 108 ELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLS 167

Query: 155 EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKL 214
             P+ LP+++E L L  N IS + + ++ GL +L  L L  N L++  L DK+F  +  L
Sbjct: 168 TIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNL 227

Query: 215 MQLNLCSNRLESMPPGLP-SSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIP 273
            +L+L  N L + P  LP ++L  L L++N I+ +P   F  L +L+ L MS+N L ++P
Sbjct: 228 TELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP 287

Query: 274 YNIF-NLPNIVELSVGHN 290
             IF +L NI +L + +N
Sbjct: 288 QGIFDDLDNITQLILRNN 305



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 83/271 (30%), Positives = 122/271 (45%), Gaps = 40/271 (14%)

Query: 54  PFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFI 112
           P       C S C C   F   +YC++R L +IP  IP     LYLQ N+I         
Sbjct: 23  PLSVMAKSCPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQIN-------- 71

Query: 113 NATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQ---LHLEHNNLEEFPFPLPKSLERLLL 169
                               + G+ + L NLL+   ++L HN+L+EFP  LPK ++ L L
Sbjct: 72  --------------------NAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHL 111

Query: 170 GYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPP 229
             N I  +  +++  +  L  L L  N +    +++  F     L  L L  N L ++P 
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171

Query: 230 GLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN---IFNLPNIVELS 286
           GLP ++  L L++N IS+I       L  L  L +  N L +        FNL N+ ELS
Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231

Query: 287 VGHNKLKQA-FYIP-RNLEHLYLQNNEIEKM 315
           +  N L  A   +P  NL  LYLQ+N I ++
Sbjct: 232 LVRNSLTAAPVNLPGTNLRKLYLQDNHINRV 262


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  122 bits (306), Expect = 6e-28
 Identities = 81/258 (31%), Positives = 134/258 (51%), Gaps = 12/258 (4%)

Query: 45  FRQNVDYGVPFHQYTLGCVSECFCPTNFPSSM---------YCDNRKLKTIP-NIPMHIQ 94
           F  ++  G+P    TL   +        PS +         Y  +  L   P N+P +++
Sbjct: 48  FLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVK 107

Query: 95  QLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLE 154
           +L+LQ N I  +T +S     +L+E++L  N + +  I+ G F     L  L L  N+L 
Sbjct: 108 ELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLS 167

Query: 155 EFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKL 214
             P+ LP+++E L L  N IS + + ++ GL +L  L L  N L++  L DK+F  +  L
Sbjct: 168 TIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNL 227

Query: 215 MQLNLCSNRLESMPPGLP-SSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIP 273
            +L+L  N L + P  LP ++L  L L++N I+ +P   F  L +L+ L MS+N L ++P
Sbjct: 228 TELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLP 287

Query: 274 YNIF-NLPNIVELSVGHN 290
             IF +L NI +L + +N
Sbjct: 288 QGIFDDLDNITQLILRNN 305



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 83/271 (30%), Positives = 122/271 (45%), Gaps = 40/271 (14%)

Query: 54  PFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFI 112
           P       C S C C   F   +YC++R L +IP  IP     LYLQ N+I         
Sbjct: 23  PLSVMAKSCPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQIN-------- 71

Query: 113 NATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQ---LHLEHNNLEEFPFPLPKSLERLLL 169
                               + G+ + L NLL+   ++L HN+L+EFP  LPK ++ L L
Sbjct: 72  --------------------NAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHL 111

Query: 170 GYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPP 229
             N I  +  +++  +  L  L L  N +    +++  F     L  L L  N L ++P 
Sbjct: 112 QENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW 171

Query: 230 GLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN---IFNLPNIVELS 286
           GLP ++  L L++N IS+I       L  L  L +  N L +        FNL N+ ELS
Sbjct: 172 GLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELS 231

Query: 287 VGHNKLKQA-FYIP-RNLEHLYLQNNEIEKM 315
           +  N L  A   +P  NL  LYLQ+N I ++
Sbjct: 232 LVRNSLTAAPVNLPGTNLRKLYLQDNHINRV 262


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score =  120 bits (301), Expect = 2e-27
 Identities = 103/384 (26%), Positives = 177/384 (46%), Gaps = 19/384 (4%)

Query: 32  DQEPDDDYQTGFPFRQNVDYGVPFH-QYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIP 90
           D+E ++D   G  FR      +P   + TL   S C        ++ C N  L  IP + 
Sbjct: 285 DEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSLSYR---TISCINAMLTQIPPLT 341

Query: 91  M-HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLE 149
              I  L L  N I ++   +F    +L+ ++LS N I S  I    F  L  L++L+++
Sbjct: 342 APQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMD 401

Query: 150 HNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFA 209
            NNL + P  LP +LE L +  N +  +   ++  L  L  L+L  N L ++ +    F 
Sbjct: 402 GNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFK 461

Query: 210 KMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKL 269
            ++ L  L L  N+   +P GLP S+  L LENN I  I E  F+   K++ + + +NK+
Sbjct: 462 PLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKI 521

Query: 270 QD---IPYNIFNLPNIVELSVGHNKLKQA-FYIPRNLEHLYLQNNEIEKMNLTVMCPSID 325
           ++    P    N  N+  + + +NKL     Y+P++L HL L  N+IE++   V      
Sbjct: 522 EENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEP 581

Query: 326 PLHYHHLTYIRVDQNKLKEPISSY--------IFFCFPHIHTIYYGEQRSTNGQTIQLKT 377
            L Y +L++ ++  + + + +S Y        +F     + +I  G Q       ++L  
Sbjct: 582 GLEYLYLSFNKLADDGM-DRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNN 640

Query: 378 QVFRR-FPDDDDESEDHDDPDNAH 400
              R   P++   +E+ DD +  H
Sbjct: 641 NKIRNILPEEICNAEEDDDSNLEH 664



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 71/275 (25%), Positives = 119/275 (43%), Gaps = 42/275 (15%)

Query: 79  DNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
           D   L  IP+ +P  +++L +  N ++A+   S  +   L  + L  N +    ++   F
Sbjct: 401 DGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAF 460

Query: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNY 197
             L +L  L L  N     P  LP S+E L L  N+I ++     +    + ++ L YN 
Sbjct: 461 KPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNK 520

Query: 198 LHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKL- 256
           + ++ +    +   E L  ++L  N+L  +P  LP SL++L L  N I  IP   F  + 
Sbjct: 521 IEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHME 580

Query: 257 PKL------------------------HTLR---MSHNKLQDIPYNIFNLPNIVELSVGH 289
           P L                        H+LR   + HN L+ IP  I  +  +  L + +
Sbjct: 581 PGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNN 640

Query: 290 NKLKQAFYIPR-----------NLEHLYLQNNEIE 313
           NK++    +P            NLEHL+L+NN I+
Sbjct: 641 NKIRNI--LPEEICNAEEDDDSNLEHLHLENNYIK 673


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  112 bits (279), Expect = 8e-25
 Identities = 83/269 (30%), Positives = 132/269 (49%), Gaps = 16/269 (5%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C C       + C +  L  +P ++P     L LQ N+I  +    F N  +L  +
Sbjct: 54  CPFRCQCHLRV---VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
            L +NKI   K+  G F  L  L +L+L  N L+E P  +PK+L+ L    NEI+K++  
Sbjct: 111 ILVNNKIS--KVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKV 168

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
             +GL  + +++L  N L  S +++  F  M+KL  + +    + S+P GLP SL  L L
Sbjct: 169 TFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHL 228

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPY-NIFNLPNIVELSVGHNKLKQAFYIP 299
           + N IS +       L  L  L +S N +  +   ++ N P++ EL + +NKL +   +P
Sbjct: 229 DGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTR---VP 285

Query: 300 RNL-EH-----LYLQNNEIEKMNLTVMCP 322
             L EH     +YL NN I  +  +  CP
Sbjct: 286 GGLAEHKYIQVVYLHNNNISVVGSSDFCP 314


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  112 bits (279), Expect = 8e-25
 Identities = 83/269 (30%), Positives = 132/269 (49%), Gaps = 16/269 (5%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C C       + C +  L  +P ++P     L LQ N+I  +    F N  +L  +
Sbjct: 54  CPFRCQCHLRV---VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
            L +NKI   K+  G F  L  L +L+L  N L+E P  +PK+L+ L    NEI+K++  
Sbjct: 111 ILVNNKIS--KVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKV 168

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
             +GL  + +++L  N L  S +++  F  M+KL  + +    + S+P GLP SL  L L
Sbjct: 169 TFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHL 228

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPY-NIFNLPNIVELSVGHNKLKQAFYIP 299
           + N IS +       L  L  L +S N +  +   ++ N P++ EL + +NKL +   +P
Sbjct: 229 DGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTR---VP 285

Query: 300 RNL-EH-----LYLQNNEIEKMNLTVMCP 322
             L EH     +YL NN I  +  +  CP
Sbjct: 286 GGLAEHKYIQVVYLHNNNISVVGSSDFCP 314


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score =  110 bits (275), Expect = 2e-24
 Identities = 64/191 (33%), Positives = 99/191 (51%), Gaps = 1/191 (0%)

Query: 80  NRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           N  L+ +P+ +P  ++ L +  N+I  +    F     L+E+NLS+N+I S ++    F 
Sbjct: 416 NNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFR 475

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
           KL  L  L L  N L   P  LP+++  L +  NE++ L   A+ G+  L  L L  N L
Sbjct: 476 KLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRL 535

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
               L  + +  +  L  L++  N+L  +P GLP SL YL L+NN IS++P   FD  P 
Sbjct: 536 RSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPN 595

Query: 259 LHTLRMSHNKL 269
           L  + +  NKL
Sbjct: 596 LKGIFLRFNKL 606



 Score =  104 bits (260), Expect = 1e-22
 Identities = 85/308 (27%), Positives = 139/308 (45%), Gaps = 14/308 (4%)

Query: 60  LGCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLK 118
           + C  +C C       + C    L+  P ++P H   L LQ N++E +          L+
Sbjct: 114 VSCPRDCACSQE--GVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLE 171

Query: 119 EINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQ 178
            +NL +N++ S+ +    F  L NL  L+L +N L   P  LP +L  +    N ++K+ 
Sbjct: 172 TLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIY 231

Query: 179 TNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYL 238
                   NL  + L  N L D+ L D +F     +  L L SN L  +P  LP +L  L
Sbjct: 232 GLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKL 291

Query: 239 SLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN---IFNLPNIVELSVGHNKLKQA 295
            L+NN +  IP   F +L  L  L + +N L D   +    + L ++  L +  N L + 
Sbjct: 292 HLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRV 351

Query: 296 -FYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEP-ISSYIFFC 353
              +PR+L  L+L+ N I  ++  V+ P         L Y+ +  N+L+E  I    F  
Sbjct: 352 PAGLPRSLVLLHLEKNAIRSVDANVLTP------IRSLEYLLLHSNQLREQGIHPLAFQG 405

Query: 354 FPHIHTIY 361
              +HT++
Sbjct: 406 LKRLHTVH 413



 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 71/257 (27%), Positives = 127/257 (49%), Gaps = 5/257 (1%)

Query: 61  GCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKE 119
           G  +E F   +    +   +  L  +P  +P  +  L+L+ N I +V AN       L+ 
Sbjct: 326 GLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEY 385

Query: 120 INLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT 179
           + L  N+++ Q I    F  L  L  +HL +N LE  P  LP+ +  L++ +N+I+ +  
Sbjct: 386 LLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGR 445

Query: 180 NAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLS 239
                   L  L+L YN +    +    F K+  L  L+L  NRL ++PPGLP ++  L 
Sbjct: 446 EDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLK 505

Query: 240 LENNSISSIPEKYFDKLPKLHTLRMSHNKLQDI---PYNIFNLPNIVELSVGHNKLKQ-A 295
           ++ N ++++       + +L  L ++ N+L+     P    +L ++  L +  N+L +  
Sbjct: 506 VKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 565

Query: 296 FYIPRNLEHLYLQNNEI 312
             +P +LE+LYLQNN+I
Sbjct: 566 EGLPESLEYLYLQNNKI 582



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 67/235 (28%), Positives = 120/235 (51%), Gaps = 5/235 (2%)

Query: 83  LKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLP 141
           L+ +P ++P  + +L+L+ N++E +   +F   + L+E+ L +N +  + +D   F KL 
Sbjct: 277 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLS 336

Query: 142 NLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDS 201
           +L  L L  NNL   P  LP+SL  L L  N I  +  N +  + +L  L L  N L + 
Sbjct: 337 SLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQ 396

Query: 202 LLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHT 261
            +    F  +++L  ++L +N LE +P GLP  +  L + +N I+ I  + F     L  
Sbjct: 397 GIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEE 456

Query: 262 LRMSHNKL--QDIPYNIF-NLPNIVELSVGHNKLKQ-AFYIPRNLEHLYLQNNEI 312
           L +S+N++    +  + F  L  +  L +  N+L      +PRN+  L ++ NE+
Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNEL 511



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 1/149 (0%)

Query: 75  SMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKID 133
           S+     +L T+P  +P ++  L ++ NE+ A+   + +    L+E+ L+ N+++S+ + 
Sbjct: 482 SLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALG 541

Query: 134 YGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 193
              +  L +L  L +  N L E P  LP+SLE L L  N+IS +  NA D   NL  + L
Sbjct: 542 PRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFL 601

Query: 194 CYNYLHDSLLKDKIFAKMEKLMQLNLCSN 222
            +N L    + D  F +++ L  L++  N
Sbjct: 602 RFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score =  108 bits (269), Expect = 1e-23
 Identities = 67/205 (32%), Positives = 111/205 (54%), Gaps = 2/205 (0%)

Query: 88  NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLH 147
           N+P  +++L+LQ N +  +  +S      L++++L  N + +  I+   FA    L  L 
Sbjct: 124 NLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLF 183

Query: 148 LEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 207
           L  N+L   P  LP +LE L L  N IS +  +A  GL +L  L L  N L +  + D  
Sbjct: 184 LSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDT 243

Query: 208 FAKMEKLMQLNLCSNRLESMPPGLPSS-LMYLSLENNSISSIPEKYFDKLPKLHTLRMSH 266
           F++++ L +L+L  N L + P  LPS+ L  L L++N+IS IP     K+ +L  L +S+
Sbjct: 244 FSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSN 303

Query: 267 NKLQDIPYNIF-NLPNIVELSVGHN 290
           N L  +P  +F +L N+ +L + +N
Sbjct: 304 NNLTTLPRGLFDDLGNLAQLLLRNN 328



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 83/257 (32%), Positives = 125/257 (48%), Gaps = 34/257 (13%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C S C C   F   +YC++R L +IP +IP     LYLQ                     
Sbjct: 54  CPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQ--------------------- 89

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
              +N+I +  I   +  K+ N+  ++L  N+L+EFP  LP+SL  L L  N +  +  +
Sbjct: 90  ---NNQINNAGIPQDLKTKV-NVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARD 145

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
           ++  +  L  L L  N +    +++  FA  ++L  L L  N L S+P GLP +L  L L
Sbjct: 146 SLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRL 205

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKL--QDIPYNIFN-LPNIVELSVGHNKL-KQAF 296
           ++N IS+IP   F  L  L  L +  N L  Q I  + F+ L N+ ELS+  N L     
Sbjct: 206 DDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPL 265

Query: 297 YIP-RNLEHLYLQNNEI 312
            +P  +L+ LYLQ+N I
Sbjct: 266 NLPSAHLQKLYLQDNAI 282


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score =  103 bits (258), Expect = 2e-22
 Identities = 78/259 (30%), Positives = 120/259 (46%), Gaps = 7/259 (2%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C CP     ++ CD   L+  P NI    Q L LQ N+++ +  N     + L+ +
Sbjct: 44  CPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
           NL +N I S+ +    F  L  L  L + HN L   P  LP+SL    L  N++ ++   
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 161

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
                  L  + L  N L ++ L    F   E +  L+L +N+L  +PP LP SL  L L
Sbjct: 162 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 221

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN---IFNLPNIVELSVGHNKLKQA-F 296
           +NN IS +P     +  +L  L + HN+L D   +      L ++  L + HN+L     
Sbjct: 222 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 281

Query: 297 YIPRNLEHLYLQNNEIEKM 315
            +PR L  L+L  N I ++
Sbjct: 282 GLPRTLAILHLGRNRIRQV 300



 Score =  100 bits (250), Expect = 2e-21
 Identities = 74/260 (28%), Positives = 126/260 (48%), Gaps = 5/260 (1%)

Query: 61  GCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKE 119
           G   + F  +   +++   N +L  +P ++P  +++L+LQ N I  V   +    T L+E
Sbjct: 183 GLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRE 242

Query: 120 INLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT 179
           + L HN++    +D   F+KL +L  L L HN L   P  LP++L  L LG N I +++ 
Sbjct: 243 LYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEA 302

Query: 180 NAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLS 239
             + G   L  L L +N L  S L       +  L  L+L  N L+ +PP LP  L  L 
Sbjct: 303 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV 362

Query: 240 LENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIF-NLPNIVELSVGHNKL-KQA 295
           L +N ++++  +     P L  L +++N+L    + +  F  L  +  L +  N+L +  
Sbjct: 363 LPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 422

Query: 296 FYIPRNLEHLYLQNNEIEKM 315
             +P  L  L LQ N++  +
Sbjct: 423 MGLPTGLRTLQLQRNQLRML 442



 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)

Query: 80  NRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           + +L T+P  +P  +  L+L  N I  V A     A  L+ + L HN++ S  +  G   
Sbjct: 273 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALR 332

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
            L  L  LHL  N L+  P  LP+ L  L+L +N ++ L    +     LT L+L YN L
Sbjct: 333 PLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRL 392

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
             + +  + F ++  L  L+L  N+L  +P GLP+ L  L L+ N +  +  +    L +
Sbjct: 393 ASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQ 452

Query: 259 LHTLRMSHNKLQ 270
           L  L ++HN+L+
Sbjct: 453 LRELSLAHNRLR 464



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 76/267 (28%), Positives = 117/267 (43%), Gaps = 9/267 (3%)

Query: 80  NRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           + KL   P  +P  ++   L  N++  +   +F     L+ + L +N++ +  +    F 
Sbjct: 131 HNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFR 190

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
               +  L L +N L   P  LP SLERL L  N ISK+   A+     L  L L +N L
Sbjct: 191 GSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQL 250

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
            DS L    F+K+  L  L+L  N+L ++P GLP +L  L L  N I  +          
Sbjct: 251 TDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARG 310

Query: 259 LHTLRMSHNKL--QDIPYNIFN-LPNIVELSVGHNKLKQA-FYIPRNLEHLYLQNNEIEK 314
           L  L + HN+L    +P      L  +  L +  N L +    +PR L  L L +N +  
Sbjct: 311 LRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAA 370

Query: 315 MNL--TVMCPSIDPLH--YHHLTYIRV 337
           +     V  P +  L+  Y+ L   RV
Sbjct: 371 LGARDLVATPGLTELNLAYNRLASARV 397



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 21/86 (24%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 89  IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLH- 147
           +P  ++ L LQ N++  +          L+E++L+HN+++   I  G + +L  L   H 
Sbjct: 425 LPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHR 484

Query: 148 -LEHNNLEEFPFP-LPKSLERLLLGY 171
            + H      P P LP  +  +L+ +
Sbjct: 485 LVSHTVPRAPPSPCLPCHVPNILVSW 510


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score =  103 bits (258), Expect = 2e-22
 Identities = 78/259 (30%), Positives = 120/259 (46%), Gaps = 7/259 (2%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C CP     ++ CD   L+  P NI    Q L LQ N+++ +  N     + L+ +
Sbjct: 46  CPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 103

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
           NL +N I S+ +    F  L  L  L + HN L   P  LP+SL    L  N++ ++   
Sbjct: 104 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 163

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
                  L  + L  N L ++ L    F   E +  L+L +N+L  +PP LP SL  L L
Sbjct: 164 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 223

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYN---IFNLPNIVELSVGHNKLKQA-F 296
           +NN IS +P     +  +L  L + HN+L D   +      L ++  L + HN+L     
Sbjct: 224 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 283

Query: 297 YIPRNLEHLYLQNNEIEKM 315
            +PR L  L+L  N I ++
Sbjct: 284 GLPRTLAILHLGRNRIRQV 302



 Score =  100 bits (250), Expect = 2e-21
 Identities = 74/260 (28%), Positives = 126/260 (48%), Gaps = 5/260 (1%)

Query: 61  GCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKE 119
           G   + F  +   +++   N +L  +P ++P  +++L+LQ N I  V   +    T L+E
Sbjct: 185 GLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRE 244

Query: 120 INLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT 179
           + L HN++    +D   F+KL +L  L L HN L   P  LP++L  L LG N I +++ 
Sbjct: 245 LYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEA 304

Query: 180 NAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLS 239
             + G   L  L L +N L  S L       +  L  L+L  N L+ +PP LP  L  L 
Sbjct: 305 ARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALV 364

Query: 240 LENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIF-NLPNIVELSVGHNKL-KQA 295
           L +N ++++  +     P L  L +++N+L    + +  F  L  +  L +  N+L +  
Sbjct: 365 LPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 424

Query: 296 FYIPRNLEHLYLQNNEIEKM 315
             +P  L  L LQ N++  +
Sbjct: 425 MGLPTGLRTLQLQRNQLRML 444



 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)

Query: 80  NRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           + +L T+P  +P  +  L+L  N I  V A     A  L+ + L HN++ S  +  G   
Sbjct: 275 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALR 334

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
            L  L  LHL  N L+  P  LP+ L  L+L +N ++ L    +     LT L+L YN L
Sbjct: 335 PLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRL 394

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
             + +  + F ++  L  L+L  N+L  +P GLP+ L  L L+ N +  +  +    L +
Sbjct: 395 ASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQ 454

Query: 259 LHTLRMSHNKLQ 270
           L  L ++HN+L+
Sbjct: 455 LRELSLAHNRLR 466



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 76/267 (28%), Positives = 117/267 (43%), Gaps = 9/267 (3%)

Query: 80  NRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           + KL   P  +P  ++   L  N++  +   +F     L+ + L +N++ +  +    F 
Sbjct: 133 HNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFR 192

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
               +  L L +N L   P  LP SLERL L  N ISK+   A+     L  L L +N L
Sbjct: 193 GSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQL 252

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
            DS L    F+K+  L  L+L  N+L ++P GLP +L  L L  N I  +          
Sbjct: 253 TDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARG 312

Query: 259 LHTLRMSHNKL--QDIPYNIFN-LPNIVELSVGHNKLKQA-FYIPRNLEHLYLQNNEIEK 314
           L  L + HN+L    +P      L  +  L +  N L +    +PR L  L L +N +  
Sbjct: 313 LRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAA 372

Query: 315 MNL--TVMCPSIDPLH--YHHLTYIRV 337
           +     V  P +  L+  Y+ L   RV
Sbjct: 373 LGARDLVATPGLTELNLAYNRLASARV 399



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 21/86 (24%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 89  IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLH- 147
           +P  ++ L LQ N++  +          L+E++L+HN+++   I  G + +L  L   H 
Sbjct: 427 LPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHR 486

Query: 148 -LEHNNLEEFPFP-LPKSLERLLLGY 171
            + H      P P LP  +  +L+ +
Sbjct: 487 LVSHTVPRAPPSPCLPCHVPNILVSW 512


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score =  102 bits (253), Expect = 9e-22
 Identities = 89/307 (28%), Positives = 140/307 (45%), Gaps = 20/307 (6%)

Query: 27  WDEDYDQEP---DDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKL 83
           WD   D  P   +D+  +G      +D       Y+  C   C C       + C +  L
Sbjct: 25  WDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRV---VQCSDLGL 81

Query: 84  KTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPN 142
           K++P  I      L LQ N+I  +  + F    HL  + L +NKI   KI    F+ L  
Sbjct: 82  KSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKIS--KIHEKAFSPLRK 139

Query: 143 LLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSL 202
           L +L++  N+L E P  LP SL  L +  N I K+      GL N+  +++  N L +S 
Sbjct: 140 LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSG 199

Query: 203 LKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTL 262
            +   F  + KL  L +   +L  +P  LP +L  L L++N I +I  +   +  KL+ L
Sbjct: 200 FEPGAFDGL-KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRL 258

Query: 263 RMSHNKLQDIPYNIFN-LPNIVELSVGHNKLKQAFYIPRNLEHL------YLQNNEIEKM 315
            + HN+++ I     + LP + EL + +NKL +   +P  L  L      YL +N I K+
Sbjct: 259 GLGHNQIRMIENGSLSFLPTLRELHLDNNKLAR---VPSGLPDLKLLQVVYLHSNNITKV 315

Query: 316 NLTVMCP 322
            +   CP
Sbjct: 316 GVNDFCP 322



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 11/194 (5%)

Query: 153 LEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKME 212
           L+  P  +      L L  N+IS+L+ +   GL +L  L L  N +  S + +K F+ + 
Sbjct: 81  LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI--SKIHEKAFSPLR 138

Query: 213 KLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDI 272
           KL +L +  N L  +PP LPSSL+ L + +N I  +P+  F  L  ++ + M  N L++ 
Sbjct: 139 KLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENS 198

Query: 273 PY--NIFNLPNIVELSVGHNKLKQ-AFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHY 329
            +    F+   +  L +   KL      +P  L  L+L +N+I+ + L       D L Y
Sbjct: 199 GFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE------DLLRY 252

Query: 330 HHLTYIRVDQNKLK 343
             L  + +  N+++
Sbjct: 253 SKLYRLGLGHNQIR 266


>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
           sapiens]
          Length = 660

 Score =  101 bits (251), Expect = 1e-21
 Identities = 65/219 (29%), Positives = 115/219 (52%), Gaps = 3/219 (1%)

Query: 75  SMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKID 133
           ++Y    +L   P N+P +++ L+LQ N I+ ++  +      L+E++L  N I +  ++
Sbjct: 92  TVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVE 151

Query: 134 YGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 193
            G F +  +L  L L  N+L   P  LP  L+ L +  N I+ +   A   L +L  L +
Sbjct: 152 DGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIV 211

Query: 194 CYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSS-LMYLSLENNSISSIPEKY 252
             N L +  + +  F+ + KL + ++  N L   PP LP + L+ L L++N I+ IP   
Sbjct: 212 DGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTA 271

Query: 253 FDKLPKLHTLRMSHNKLQDIPYNIF-NLPNIVELSVGHN 290
           F  L KL  L +S+N+L+ +   +F NL N+ +L+  +N
Sbjct: 272 FSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 82/276 (29%), Positives = 116/276 (42%), Gaps = 56/276 (20%)

Query: 60  LGCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLK 118
           L C S C C  NF   +YC+ R L ++P  IP  +  LYL  N+I               
Sbjct: 34  LACPSVCRCDRNF---VYCNERSLTSVPLGIPEGVTVLYLHNNQIN-------------- 76

Query: 119 EINLSHNKIKSQKIDYGVFAKLPNLLQLH---LEHNNLEEFPFPLPKSLERLLLGYNEIS 175
                         + G  A+L N+  +H   L  N L+EFP  LPK++  L L  N I 
Sbjct: 77  --------------NAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQ 122

Query: 176 KLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSL 235
            +   A+  L+ L  L L  N +    ++D  F +   L  L L  N L S+P GLP  L
Sbjct: 123 TISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDL 182

Query: 236 MYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGH-NKLKQ 294
             L ++ N I+ I +  F  L  L  L +  N L +          I E +  H  KLK+
Sbjct: 183 QELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTN--------KGIAEGTFSHLTKLKE 234

Query: 295 AFYIPRNLEH------------LYLQNNEIEKMNLT 318
              +  +L H            LYLQ+N+I  + LT
Sbjct: 235 FSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLT 270



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 30/140 (21%)

Query: 220 CSNR-LESMPPGLPSSLMYLSLENNSISS--IPEKYFDKLPKLHTLRMSHNKLQDIPYNI 276
           C+ R L S+P G+P  +  L L NN I++   P +    +  +HT+ +  N+L + P N 
Sbjct: 49  CNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAE-LHNVQSVHTVYLYGNQLDEFPMN- 106

Query: 277 FNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCP--SIDPLHY--HHL 332
                                +P+N+  L+LQ N I+ ++   +     ++ LH   + +
Sbjct: 107 ---------------------LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSI 145

Query: 333 TYIRVDQNKLKEPISSYIFF 352
           + + V+    +E IS  + F
Sbjct: 146 STVGVEDGAFREAISLKLLF 165


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 78/278 (28%), Positives = 131/278 (47%), Gaps = 17/278 (6%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121
           C   C C ++    + CD   L+ IP +    + L LQ N    + ANSF    +L  ++
Sbjct: 23  CPQNCHCHSDL-QHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLH 81

Query: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEF---PFPLPKSLERLLLGYNEISKLQ 178
           L H +I+  ++  G F  L  L+ L+L HN++       F     L  L L +N++++L 
Sbjct: 82  LQHCQIR--EVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELP 139

Query: 179 TNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYL 238
              +  LVNL +L L  N + +  L+   F   + L  L L  N L S+ PG    +  L
Sbjct: 140 RGLLSPLVNLFILQLNNNKIRE--LRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENL 197

Query: 239 S---LENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNL--PNIVELSVGHNKLK 293
           +   ++ N +SS P     KL  +  L++SHN L+ IP N F      +  L + +  L+
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257

Query: 294 Q----AFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPL 327
           +    AF     L+H++L+NN + ++       S++ L
Sbjct: 258 KFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETL 295


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 59/192 (30%), Positives = 96/192 (50%), Gaps = 1/192 (0%)

Query: 80  NRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFA 138
           + +L T+P  +P  +  L+L  N I  V A     A  L+ + L HN++ S  +  G   
Sbjct: 184 HNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALR 243

Query: 139 KLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 198
            L  L  LHL  N L+  P  LP+ L  L+L +N ++ L    +     LT L+L YN L
Sbjct: 244 PLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRL 303

Query: 199 HDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPK 258
             + +  + F ++  L  L+L  N+L  +P GLP+ L  L L+ N +  +  +    L +
Sbjct: 304 ASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQ 363

Query: 259 LHTLRMSHNKLQ 270
           L  L ++HN+L+
Sbjct: 364 LRELSLAHNRLR 375



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 66/228 (28%), Positives = 108/228 (47%), Gaps = 4/228 (1%)

Query: 92  HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN 151
           H+   + + N I  V   +    T L+E+ L HN++    +D   F+KL +L  L L HN
Sbjct: 126 HLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHN 185

Query: 152 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 211
            L   P  LP++L  L LG N I +++   + G   L  L L +N L  S L       +
Sbjct: 186 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 245

Query: 212 EKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD 271
             L  L+L  N L+ +PP LP  L  L L +N ++++  +     P L  L +++N+L  
Sbjct: 246 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305

Query: 272 --IPYNIF-NLPNIVELSVGHNKL-KQAFYIPRNLEHLYLQNNEIEKM 315
             + +  F  L  +  L +  N+L +    +P  L  L LQ N++  +
Sbjct: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRML 353



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 80/285 (28%), Positives = 118/285 (41%), Gaps = 29/285 (10%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C CP     ++ CD   L+  P NI    Q L LQ N+++ +  N     + L+ +
Sbjct: 44  CPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTN 180
           NL +N I S+ +    F  L  L  L + HN                    N ISK+   
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRG 143

Query: 181 AMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSL 240
           A+     L  L L +N L DS L    F+K+  L  L+L  N+L ++P GLP +L  L L
Sbjct: 144 ALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHL 203

Query: 241 ENNSISSIPEKYFDKLPKLHTLRMSHNKL--QDIPYNIFN-LPNIVELSVGHNKLKQA-F 296
             N I  +          L  L + HN+L    +P      L  +  L +  N L +   
Sbjct: 204 GRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPP 263

Query: 297 YIPRNLEHLYLQNNEIEKMNL--TVMCPSIDPLH--YHHLTYIRV 337
            +PR L  L L +N +  +     V  P +  L+  Y+ L   RV
Sbjct: 264 ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARV 308



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 21/86 (24%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 89  IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLH- 147
           +P  ++ L LQ N++  +          L+E++L+HN+++   I  G + +L  L   H 
Sbjct: 336 LPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHR 395

Query: 148 -LEHNNLEEFPFP-LPKSLERLLLGY 171
            + H      P P LP  +  +L+ +
Sbjct: 396 LVSHTVPRAPPSPCLPCHVPNILVSW 421


>gi|20302168 toll-like receptor 8 [Homo sapiens]
          Length = 1041

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 79/259 (30%), Positives = 121/259 (46%), Gaps = 24/259 (9%)

Query: 78  CDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNK---------- 126
           C NR+L+ +P  +  ++ +L L  N I  +T  SF    +L +INL+HN           
Sbjct: 49  CSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPG 108

Query: 127 IKSQKIDY--GVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDG 184
           I+S  ++   G F  L NL +L LE N L + P  LP+SL  L L  N I  +    +  
Sbjct: 109 IQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISR 168

Query: 185 LVNLTMLDLCYNYLHDSL-----LKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLS 239
           L+NL  L L +N   + +     ++D +F  +  L  L+L  N L  +PP LPSSL  L 
Sbjct: 169 LINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLF 228

Query: 240 LENNSISSIPEKYFDKLPKLHTLRMSHN--KLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
           L N  I  I E+ F  L  L  L +S N  +  + P+          +++     + AF 
Sbjct: 229 LSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINID----RFAFQ 284

Query: 298 IPRNLEHLYLQNNEIEKMN 316
               L +L L +  + K+N
Sbjct: 285 NLTQLRYLNLSSTSLRKIN 303



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 84/314 (26%), Positives = 134/314 (42%), Gaps = 43/314 (13%)

Query: 79  DNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLS----HNKI-KSQKI 132
           ++ +L  IP+ +P  + +L L  N I  +T        +LK + L+     NK+ +   I
Sbjct: 133 EDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNI 192

Query: 133 DYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLD 192
           + GVF  L NL  L L  N+L   P  LP SL +L L   +I  +      GL+NLT+LD
Sbjct: 193 EDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLD 252

Query: 193 L------CYNYLHDSLLKD-KIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSI 245
           L      C+N     +  D      +++    NL             + L YL+L + S+
Sbjct: 253 LSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNL-------------TQLRYLNLSSTSL 299

Query: 246 SSIPEKYFDKLPKLHTLRMSHNKL-QDIPYNIF--NLPNIVELSVGHNKLK----QAFYI 298
             I   +F  +P L  L +  N L  +I    F   LP +  L +  N +K    Q   I
Sbjct: 300 RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINI 359

Query: 299 PRN------LEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFF 352
            RN      L  L+L+    +++      P    +   +L+ I +  N +K+ I   +F 
Sbjct: 360 SRNFSKLLSLRALHLRGYVFQELREDDFQPL---MQLPNLSTINLGINFIKQ-IDFKLFQ 415

Query: 353 CFPHIHTIYYGEQR 366
            F ++  IY  E R
Sbjct: 416 NFSNLEIIYLSENR 429



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/201 (27%), Positives = 85/201 (42%), Gaps = 42/201 (20%)

Query: 113 NATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYN 172
           N T+LK +NLSHN I +    Y            +LE  +L E  F    S  RL + +N
Sbjct: 582 NFTNLKVLNLSHNNIYTLTDKY------------NLESKSLVELVF----SGNRLDILWN 625

Query: 173 EISKLQTNAMDGLVNLTMLDLCYN--------------------YLHDSLLKD---KIFA 209
           +      +   GL NLT LDL  N                    +++D++LK     +  
Sbjct: 626 DDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ 685

Query: 210 KMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSH 266
           +  +L  L+L  N+L  +   L    SSL  L L +N IS +P  +  ++  L  L +S 
Sbjct: 686 QFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSS 745

Query: 267 NKLQDIPYNIFNLPNIVELSV 287
           N L+ I  +        +LS+
Sbjct: 746 NLLKTINKSALETKTTTKLSM 766



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 60/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)

Query: 87  PNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQL 146
           P    + + L L  N I  +  N F N   +  +NLS N   +Q +    F+ +P++  L
Sbjct: 477 PQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANS-NAQVLSGTEFSAIPHVKYL 535

Query: 147 HLEHNNLE---EFPFPLPKSLERLLLGYN----EISKL--QTNAMDGLVNLTMLDLCYNY 197
            L +N L+            LE L L YN     I+ +      +    NL +L+L +N 
Sbjct: 536 DLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNN 595

Query: 198 LHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLP 257
           ++   L DK   + + L++L    NRL+         +++   +N  IS      F  L 
Sbjct: 596 IY--TLTDKYNLESKSLVELVFSGNRLD---------ILWNDDDNRYIS-----IFKGLK 639

Query: 258 KLHTLRMSHNKLQDIPYNIF-NLP-NIVELSVGHNKLK 293
            L  L +S N+L+ IP   F NLP ++ EL +  N LK
Sbjct: 640 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLK 677



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 10/143 (6%)

Query: 79  DNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINA-THLKEINLSHNKIKSQKIDYGVF 137
           DNR +     +  ++ +L L  N ++ +   +F+N    L E++++ N +K    ++ + 
Sbjct: 628 DNRYISIFKGLK-NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF--FNWTLL 684

Query: 138 AKLPNLLQLHLEHNNLEEFPFPLP---KSLERLLLGYNEISKLQTNAMDGLVNLTMLDLC 194
            + P L  L L  N L      L     SL  LLL +N IS L +  +  + +L  LDL 
Sbjct: 685 QQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLS 744

Query: 195 YNYL---HDSLLKDKIFAKMEKL 214
            N L   + S L+ K   K+  L
Sbjct: 745 SNLLKTINKSALETKTTTKLSML 767



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 60/235 (25%), Positives = 99/235 (42%), Gaps = 31/235 (13%)

Query: 88  NIPMHIQQLYLQFNEIEA-VTANSFINAT-HLKEINLSHNKIKS---QKIDYGV-FAKLP 141
           N+P H++ L L+FN +   + + +F+     L+ ++LS N IK    Q I+    F+KL 
Sbjct: 309 NMP-HLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLL 367

Query: 142 NLLQLHLEHNNLEEF------PFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCY 195
           +L  LHL     +E       P     +L  + LG N I ++         NL ++ L  
Sbjct: 368 SLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSE 427

Query: 196 N------------YLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL-PSSLMY---LS 239
           N            Y + S  +  I  +     + +  SN      P + P    Y   L 
Sbjct: 428 NRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALD 487

Query: 240 LENNSISSIPEKYFDKLPKLHTLRMSHN-KLQDIPYNIFN-LPNIVELSVGHNKL 292
           L  NSI  I    F+ LP +  L +S N   Q +    F+ +P++  L + +N+L
Sbjct: 488 LSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRL 542


>gi|51317373 netrin-G1 ligand [Homo sapiens]
          Length = 640

 Score = 92.0 bits (227), Expect = 9e-19
 Identities = 81/259 (31%), Positives = 121/259 (46%), Gaps = 14/259 (5%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C S C C   F S + C  + L+ +P+ I  + + L L  N+I+ +  NSF +  HL+ +
Sbjct: 47  CPSVCSCSNQF-SKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEIL 105

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKL 177
            LS N I++  I+ G F  L NL  L L  N L   P   F     L+ L L  N I  +
Sbjct: 106 QLSRNHIRT--IEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESI 163

Query: 178 QTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLP-SSLM 236
            + A + + +L  LDL       S + +  F  +  L  LNL    L  +P   P   L 
Sbjct: 164 PSYAFNRIPSLRRLDL-GELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLD 222

Query: 237 YLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIF-NLPNIVELSVGHNKL--- 292
            L L  N +S+I    F  L  L  L M  +++Q I  N F NL ++VE+++ HN L   
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLL 282

Query: 293 -KQAFYIPRNLEHLYLQNN 310
               F    +LE ++L +N
Sbjct: 283 PHDLFTPLHHLERIHLHHN 301


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 92.0 bits (227), Expect = 9e-19
 Identities = 83/267 (31%), Positives = 128/267 (47%), Gaps = 17/267 (6%)

Query: 61  GCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKE 119
           GC S C C    P +++C  R+  T+P ++P     LY+  N I  + A SF     L+ 
Sbjct: 23  GCPSGCQCSQ--PQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQL 80

Query: 120 INLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISK 176
           ++LS N+I S  +  GVF  L NL  L L  N L E     F   + LERL LG N I  
Sbjct: 81  LDLSQNQIAS--LPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRH 138

Query: 177 LQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGL--PSS 234
           +Q  A D L  L  L L      D+ L+     ++ +L+ L+L  N L ++ PG+   ++
Sbjct: 139 IQPGAFDTLDRLLELKL-----QDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTAN 193

Query: 235 LMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQ 294
           +  L L    +  + E  F +L  LH L +S N+L+ +P  I  L  +  L +  N  + 
Sbjct: 194 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN-TRI 252

Query: 295 AFYIPRNLEHL-YLQNNEIEKMNLTVM 320
           A   P +L  L  LQ  ++  ++L  +
Sbjct: 253 AQLRPEDLAGLAALQELDVSNLSLQAL 279



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 15/118 (12%)

Query: 230 GLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIF-NLPNIVELSVG 288
           GLP  L  L L  N I+S+P   F  L  L  L ++ N+L +I    F  L  +  L +G
Sbjct: 74  GLPG-LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLG 132

Query: 289 HNKLKQ----AFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKL 342
            N+++     AF     L  L LQ+NE+          ++ PL    L  + +  N L
Sbjct: 133 KNRIRHIQPGAFDTLDRLLELKLQDNELR---------ALPPLRLPRLLLLDLSHNSL 181


>gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo
           sapiens]
          Length = 754

 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 83/289 (28%), Positives = 135/289 (46%), Gaps = 21/289 (7%)

Query: 59  TLGCVSECF------CPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFI 112
           ++    ECF      C     + + C N  LK++P I  ++  L L+ N+I ++    FI
Sbjct: 99  SVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFI 158

Query: 113 NATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLER---LLL 169
             T LK+I L HN I+   I    F  L NL  L+L HN +      + K L +   L+L
Sbjct: 159 KYTKLKKIFLQHNCIR--HISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLIL 216

Query: 170 GYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPP 229
             N I+++      GL +L  L +  NYL    L  ++ A+M +L  ++L  NR++ +  
Sbjct: 217 DDNPITRISQRLFTGLNSLFFLSMVNNYL--EALPKQMCAQMPQLNWVDLEGNRIKYLTN 274

Query: 230 GL---PSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIF-NLPNIVEL 285
                  SL  L L  N I  +PEK F  L  L  L +S N + ++  ++F +L  + +L
Sbjct: 275 STFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKL 334

Query: 286 SVGHNKL----KQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYH 330
           ++  N L    K  F   + L+ L L+  EI  +N  +  P  +  H +
Sbjct: 335 NLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIY 383


>gi|225579152 insulin-like growth factor binding protein, acid
           labile subunit isoform 1 precursor [Homo sapiens]
          Length = 643

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 81/284 (28%), Positives = 128/284 (45%), Gaps = 19/284 (6%)

Query: 47  QNVDYGVPFHQYTLGCVSECFCPTNFPS---SMYCDNRKLKTIPN-IPMHIQQLYLQFNE 102
           +  D G P       C + C C  +  +   S++C +R L  +P+ +P   Q L+L  N 
Sbjct: 64  EGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNN 123

Query: 103 IEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP---FP 159
           + +V   +F N + L  +NL   ++ S  ++      L NL  LHLE N L       F 
Sbjct: 124 LSSVPPAAFQNLSSLGFLNLQGGQLGS--LEPQALLGLENLCHLHLERNQLRSLALGTFA 181

Query: 160 LPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNL 219
              +L  L L  N +S+L+    +GL +L  L+L +N L  ++L D  F  +  L +L L
Sbjct: 182 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL--AVLPDAAFRGLGSLRELVL 239

Query: 220 CSNRLESMPPGLPS---SLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDI-PYN 275
             NRL  + P L S    L  L L  N++ +I    F +LP+L  L +  N +  + P  
Sbjct: 240 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 299

Query: 276 IFNLPNIVELSVGHNK----LKQAFYIPRNLEHLYLQNNEIEKM 315
              L  +  L + HN+    L+  F     L  L L +N I  +
Sbjct: 300 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 343



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 59/277 (21%)

Query: 93  IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN- 151
           +Q+LYL  N I AV   +F+    L+ ++LSHN++     D   F  L  L  L L HN 
Sbjct: 282 LQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLED--TFPGLLGLRVLRLSHNA 339

Query: 152 --NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSL------- 202
             +L    F     LE L LG+N I +L   + +GL  L +L L +N L +         
Sbjct: 340 IASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGL 399

Query: 203 ---------------LKDKIFAKMEKLMQLNLCSNRLESMPP----GLP----------- 232
                          L +++F  + KL  L+L  + L  + P    GL            
Sbjct: 400 TNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNG 459

Query: 233 ------------SSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFN-L 279
                       + L+ L L +N ++ +P + F  L KL  L +S N+L ++P +    L
Sbjct: 460 LVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 519

Query: 280 PNIVELSVGHNKLK---QAFYIP-RNLEHLYLQNNEI 312
                L V HN+L+    +   P   L +L L+NN +
Sbjct: 520 QRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSL 556



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 17/163 (10%)

Query: 208 FAKMEKLMQLNLCSNRLESMPP----GLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLR 263
           F  +  L  LNL   +L S+ P    GL  +L +L LE N + S+    F   P L +L 
Sbjct: 132 FQNLSSLGFLNLQGGQLGSLEPQALLGL-ENLCHLHLERNQLRSLALGTFAHTPALASLG 190

Query: 264 MSHNKLQDIPYNIF-NLPNIVELSVGHNKL----KQAFYIPRNLEHLYLQNNEIEKMNLT 318
           +S+N+L  +   +F  L ++ +L++G N L      AF    +L  L L  N +  +   
Sbjct: 191 LSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPA 250

Query: 319 VMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIY 361
           +     +      L  + + +N L+  I + +F   P +  +Y
Sbjct: 251 LFSGLAE------LRELDLSRNALR-AIKANVFVQLPRLQKLY 286


>gi|4826772 insulin-like growth factor binding protein, acid labile
           subunit isoform 2 precursor [Homo sapiens]
          Length = 605

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 81/284 (28%), Positives = 128/284 (45%), Gaps = 19/284 (6%)

Query: 47  QNVDYGVPFHQYTLGCVSECFCPTNFPS---SMYCDNRKLKTIPN-IPMHIQQLYLQFNE 102
           +  D G P       C + C C  +  +   S++C +R L  +P+ +P   Q L+L  N 
Sbjct: 26  EGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNN 85

Query: 103 IEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP---FP 159
           + +V   +F N + L  +NL   ++ S  ++      L NL  LHLE N L       F 
Sbjct: 86  LSSVPPAAFQNLSSLGFLNLQGGQLGS--LEPQALLGLENLCHLHLERNQLRSLALGTFA 143

Query: 160 LPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNL 219
              +L  L L  N +S+L+    +GL +L  L+L +N L  ++L D  F  +  L +L L
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL--AVLPDAAFRGLGSLRELVL 201

Query: 220 CSNRLESMPPGLPS---SLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDI-PYN 275
             NRL  + P L S    L  L L  N++ +I    F +LP+L  L +  N +  + P  
Sbjct: 202 AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGA 261

Query: 276 IFNLPNIVELSVGHNK----LKQAFYIPRNLEHLYLQNNEIEKM 315
              L  +  L + HN+    L+  F     L  L L +N I  +
Sbjct: 262 FLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 305



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 59/277 (21%)

Query: 93  IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN- 151
           +Q+LYL  N I AV   +F+    L+ ++LSHN++     D   F  L  L  L L HN 
Sbjct: 244 LQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLED--TFPGLLGLRVLRLSHNA 301

Query: 152 --NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSL------- 202
             +L    F     LE L LG+N I +L   + +GL  L +L L +N L +         
Sbjct: 302 IASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGL 361

Query: 203 ---------------LKDKIFAKMEKLMQLNLCSNRLESMPP----GLP----------- 232
                          L +++F  + KL  L+L  + L  + P    GL            
Sbjct: 362 TNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNG 421

Query: 233 ------------SSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFN-L 279
                       + L+ L L +N ++ +P + F  L KL  L +S N+L ++P +    L
Sbjct: 422 LVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 481

Query: 280 PNIVELSVGHNKLK---QAFYIP-RNLEHLYLQNNEI 312
                L V HN+L+    +   P   L +L L+NN +
Sbjct: 482 QRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSL 518



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 17/163 (10%)

Query: 208 FAKMEKLMQLNLCSNRLESMPP----GLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLR 263
           F  +  L  LNL   +L S+ P    GL  +L +L LE N + S+    F   P L +L 
Sbjct: 94  FQNLSSLGFLNLQGGQLGSLEPQALLGL-ENLCHLHLERNQLRSLALGTFAHTPALASLG 152

Query: 264 MSHNKLQDIPYNIF-NLPNIVELSVGHNKL----KQAFYIPRNLEHLYLQNNEIEKMNLT 318
           +S+N+L  +   +F  L ++ +L++G N L      AF    +L  L L  N +  +   
Sbjct: 153 LSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPA 212

Query: 319 VMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIY 361
           +     +      L  + + +N L+  I + +F   P +  +Y
Sbjct: 213 LFSGLAE------LRELDLSRNALR-AIKANVFVQLPRLQKLY 248


>gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo
           sapiens]
          Length = 322

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 64/217 (29%), Positives = 97/217 (44%), Gaps = 29/217 (13%)

Query: 66  CFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHN 125
           C   T   +++YCD+ +L  IP +P +    Y +FN I+ +  N F + + LK I+L+ N
Sbjct: 118 CLLCTCISTTVYCDDHELDAIPPLPKNTAYFYSRFNRIKKINKNDFASLSDLKRIDLTSN 177

Query: 126 KIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGL 185
            I   +ID   F KLP L +L L  N + + P  LP                        
Sbjct: 178 LI--SEIDEDAFRKLPQLRELVLRDNKIRQLP-ELP------------------------ 210

Query: 186 VNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSI 245
             LT +D+  N L    +K + F  M  L  L L  N L+ +P  LP +L  L L+NN+I
Sbjct: 211 TTLTFIDISNNRLGRKGIKQEAFKDMYDLHHLYLTDNNLDHIPLPLPENLRALHLQNNNI 270

Query: 246 SSIPEKYFDKLPKLHTLR--MSHNKLQDIPYNIFNLP 280
             + E  F  +  L  +R  +   +L   P N+   P
Sbjct: 271 LEMHEDTFCNVKNLTYIRKALEDIRLDGNPINLSKTP 307



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 58/216 (26%), Positives = 100/216 (46%), Gaps = 31/216 (14%)

Query: 146 LHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKD 205
           ++ + + L+  P PLPK+       +N I K+  N    L +L  +DL  N + +  + +
Sbjct: 128 VYCDDHELDAIP-PLPKNTAYFYSRFNRIKKINKNDFASLSDLKRIDLTSNLISE--IDE 184

Query: 206 KIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSIS--SIPEKYFDKLPKLHTLR 263
             F K+ +L +L L  N++  +P  LP++L ++ + NN +    I ++ F  +  LH L 
Sbjct: 185 DAFRKLPQLRELVLRDNKIRQLPE-LPTTLTFIDISNNRLGRKGIKQEAFKDMYDLHHLY 243

Query: 264 MSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPS 323
           ++ N L  IP     LP                 +P NL  L+LQNN I +M+    C +
Sbjct: 244 LTDNNLDHIP-----LP-----------------LPENLRALHLQNNNILEMHEDTFC-N 280

Query: 324 IDPLHY--HHLTYIRVDQNKLKEPISSYIFFCFPHI 357
           +  L Y    L  IR+D N +    +   + C P +
Sbjct: 281 VKNLTYIRKALEDIRLDGNPINLSKTPQAYMCLPRL 316


>gi|7657419 opticin precursor [Homo sapiens]
          Length = 332

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 74/218 (33%), Positives = 96/218 (44%), Gaps = 32/218 (14%)

Query: 66  CFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHN 125
           C C     SS+YCD+  L+ IP +P     LY +FN I  + A  F   T LK I+LS+N
Sbjct: 131 CVC---LGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNN 187

Query: 126 KIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGL 185
            I S  ID   F  L  L  L L  N LE  P  LP  +E                    
Sbjct: 188 LISS--IDNDAFRLLHALQDLILPENQLEALPV-LPSGIE-------------------- 224

Query: 186 VNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSI 245
                LD+  N L  S ++   F  MEKL  L L  N L+S+P  LP SL  + L+NN I
Sbjct: 225 ----FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLI 280

Query: 246 SSIPEKYF-DKLPKLHTLRMSHN-KLQDIPYNIFNLPN 281
            ++    F D     HT R   + +L   P N+   P+
Sbjct: 281 ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPS 318



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 63/212 (29%), Positives = 94/212 (44%), Gaps = 35/212 (16%)

Query: 152 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 211
           +LE+ P PLP+    L   +N IS+++     GL  L  +DL  N +  S + +  F  +
Sbjct: 144 DLEDIP-PLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLI--SSIDNDAFRLL 200

Query: 212 EKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISS--IPEKYFDKLPKLHTLRMSHNKL 269
             L  L L  N+LE++P  LPS + +L +  N + S  I    F  + KL  L +S N L
Sbjct: 201 HALQDLILPENQLEALPV-LPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLL 259

Query: 270 QDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHY 329
             IP  +                      P +L  ++LQNN IE M   V C   DP  +
Sbjct: 260 DSIPGPL----------------------PLSLRSVHLQNNLIETMQRDVFC---DPEEH 294

Query: 330 HH----LTYIRVDQNKLKEPISSYIFFCFPHI 357
            H    L  IR+D N +   +    +FC P +
Sbjct: 295 KHTRRQLEDIRLDGNPINLSLFPSAYFCLPRL 326


>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
          Length = 713

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 78/262 (29%), Positives = 118/262 (45%), Gaps = 40/262 (15%)

Query: 62  CVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINATHLKEI 120
           C   C C +N  S + C  R L  +P +IP++ + L LQ N I+ +  ++F +  HL+ +
Sbjct: 57  CPVACSC-SNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEIL 115

Query: 121 NLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFP----------------------- 157
            LS N ++  KI+ G F  LP+L  L L  N L   P                       
Sbjct: 116 QLSKNLVR--KIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESI 173

Query: 158 ----FPLPKSLERLLLG-YNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKME 212
               F    SL RL LG    +  +   A +GLVNL  L+L    L D          + 
Sbjct: 174 PSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDI----PNLTALV 229

Query: 213 KLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKL 269
           +L +L L  NRL+ + PG     +SL  L L +  +++I    FD L  L  L +SHN L
Sbjct: 230 RLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNL 289

Query: 270 QDIPYNIFN-LPNIVELSVGHN 290
             +P+++F  L  +  + + HN
Sbjct: 290 MSLPHDLFTPLHRLERVHLNHN 311



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 6/103 (5%)

Query: 219 LCSNR-LESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIF 277
           +C+ R L  +P  +P +  YL+L+ N I  I    F  L  L  L++S N ++ I    F
Sbjct: 71  ICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAF 130

Query: 278 N-LPNIVELSVGHNKLK----QAFYIPRNLEHLYLQNNEIEKM 315
           N LP++  L +  N+L     QAF     L  L+L+NN IE +
Sbjct: 131 NGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESI 173


>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
           sapiens]
          Length = 587

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 87/321 (27%), Positives = 135/321 (42%), Gaps = 70/321 (21%)

Query: 52  GVPFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANS 110
           G+ +H    GC SEC C     S + C   ++  +P  +P +   L +    I  +  + 
Sbjct: 25  GLAYH----GCPSECTCSR--ASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESP 78

Query: 111 FINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPK---SLERL 167
           F+N + L  + +  N++   +I  G F  L +L  L L +N L+  P  L +   SLE L
Sbjct: 79  FLNISALIALRIEKNELS--RITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESL 136

Query: 168 LLGYNEISKLQT------------------------NAMDGLVNLTMLDLCYNYLHDSLL 203
           LL  N++ ++Q                          A D LV LT L+L  N L  + +
Sbjct: 137 LLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSL--THI 194

Query: 204 KDKIFAKMEKLMQLNLCSNRLESMP------------------------PGL---PSSLM 236
             ++F  +  L  L L  NRL  +P                        PGL     +L 
Sbjct: 195 SPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQ 254

Query: 237 YLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFN-LPNIVELSVGHNKLK-- 293
            L L NN IS +P   F +LP+L+ L +  N L+++   IF  +PN+ EL +  N +   
Sbjct: 255 RLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSL 314

Query: 294 --QAFYIPRNLEHLYLQNNEI 312
               F   R L+ L L  N+I
Sbjct: 315 PDNVFSNLRQLQVLILSRNQI 335



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 61/208 (29%), Positives = 110/208 (52%), Gaps = 13/208 (6%)

Query: 91  MHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEH 150
           +++Q+L LQ N+I  ++   F N  +L+ + LS+N I   ++   +F +LP L +L L  
Sbjct: 227 VNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSIFMQLPQLNRLTLFG 284

Query: 151 NNLEEFPF----PLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDK 206
           N+L+E       P+P +L  L L  N IS L  N    L  L +L L  N +  S +   
Sbjct: 285 NSLKELSLGIFGPMP-NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQI--SFISPG 341

Query: 207 IFAKMEKLMQLNLCSNRLESMPPG---LPSSLMYLSLENNSISSIPEKYFDKLPKLHTLR 263
            F  + +L +L+L +N L+ +      + ++L  +SL+NN +  +P   F  +  L  ++
Sbjct: 342 AFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQ 401

Query: 264 MSHNKLQDIPYNIF-NLPNIVELSVGHN 290
           + +N+L+++P  IF +L  + EL +  N
Sbjct: 402 LQNNQLENLPLGIFDHLGKLCELRLYDN 429


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,237,635
Number of Sequences: 37866
Number of extensions: 804999
Number of successful extensions: 5574
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 3185
Number of HSP's gapped (non-prelim): 1083
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.