Guide to the Human Genome
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Search of human proteins with 4826734

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826734 fusion (involved in t(12;16) in malignant
liposarcoma) [Homo sapiens]
         (526 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...  1128   0.0  
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...   464   e-130
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...   459   e-129
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...   458   e-129
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...   457   e-129
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]         407   e-113
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]          404   e-112
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...   152   7e-37
gi|62122917 filaggrin family member 2 [Homo sapiens]                  148   1e-35
gi|57864582 hornerin [Homo sapiens]                                   139   6e-33
gi|55956899 keratin 9 [Homo sapiens]                                  101   1e-21
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...   101   2e-21
gi|55956788 nucleolin [Homo sapiens]                                   98   2e-20
gi|195972866 keratin 10 [Homo sapiens]                                 97   5e-20
gi|109255251 loricrin [Homo sapiens]                                   97   5e-20
gi|119395750 keratin 1 [Homo sapiens]                                  95   1e-19
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    94   3e-19
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    94   3e-19
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    94   4e-19
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              93   7e-19
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...    92   9e-19
gi|109452587 family with sequence similarity 98, member B isofor...    92   1e-18
gi|186928829 dermokine isoform 4 precursor [Homo sapiens]              91   2e-18
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]               91   2e-18
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    91   2e-18
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    91   2e-18
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    91   2e-18
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]              91   3e-18
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    90   6e-18
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    90   6e-18

>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 1128 bits (2917), Expect = 0.0
 Identities = 526/526 (100%), Positives = 526/526 (100%)

Query: 1   MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60
           MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ
Sbjct: 1   MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60

Query: 61  SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120
           SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS
Sbjct: 61  SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120

Query: 121 SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD 180
           SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD
Sbjct: 121 SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD 180

Query: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE 240
           QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE
Sbjct: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE 240

Query: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES 300
           PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES
Sbjct: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES 300

Query: 301 VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS 360
           VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS
Sbjct: 301 VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS 360

Query: 361 GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420
           GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ
Sbjct: 361 GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420

Query: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480
           QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD
Sbjct: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480

Query: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526
           RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY
Sbjct: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score =  464 bits (1193), Expect = e-130
 Identities = 298/623 (47%), Positives = 360/623 (57%), Gaps = 120/623 (19%)

Query: 1   MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
           MAS DY+      A Q Y AY  QP QGY+Q ++Q YGQQSY  Y Q TD        T+
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59

Query: 49  GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91
            YGQ++Y+ SYGQ   TGY T + PQ Y        TG Y +          S ++QS+Y
Sbjct: 60  TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 92  GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151
           G Q +YP YGQQPA ++ + SY SS+Q +SY Q    SYSQQ +YG Q  SYGQQ SY  
Sbjct: 119 GTQPAYPAYGQQPAATAPT-SY-SSTQPTSYDQ---SSYSQQNTYG-QPSSYGQQSSYGQ 172

Query: 152 PQGYGQQ--NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYG 209
              YGQQ    Y   +G         +Y Q  S  S    S G   +  Q      G YG
Sbjct: 173 QSSYGQQPPTSYPPQTG---------SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG 223

Query: 210 QQDRG----GRGRGGSGGGGGGGG-GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK 264
           Q+  G    G  R  SG    G G GG++R  GG    GRGGGRGG G  G  +RGGFNK
Sbjct: 224 QESGGFSGPGENRSMSGPDNRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNK 279

Query: 265 FGGPRDQGSRHD-----SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQ 319
            GGP D+G   D        ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQ
Sbjct: 280 PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ 339

Query: 320 PMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--R 377
           PMI++Y D+ETGK KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++   N  R
Sbjct: 340 PMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMR 399

Query: 378 GGGNGRGGRG-----RGGPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGG 419
           GG   R GRG     RGGP G GG GG     G  GG RGGFP  G         GGG  
Sbjct: 400 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 459

Query: 420 QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG- 465
           Q RAGDW+CPNP C N NF+WR ECNQCKAPKP+G        PG     GGPGG   G 
Sbjct: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519

Query: 466 ------GNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RG 504
                 G  G   RGGRGG DRGG+R GRG DRGGF GGR GG               RG
Sbjct: 520 GGLMDRGGPGGMFRGGRGG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRG 578

Query: 505 G-FGPGKMDSRGEHRQDRRERPY 526
           G  GPGKMD +GEHRQ+RR+RPY
Sbjct: 579 GRGGPGKMD-KGEHRQERRDRPY 600


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score =  459 bits (1180), Expect = e-129
 Identities = 297/661 (44%), Positives = 358/661 (54%), Gaps = 141/661 (21%)

Query: 1   MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
           MAS DY+      A Q Y AY  QP QGY+Q ++Q YGQQSY  Y Q TD        T+
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59

Query: 49  GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91
            YGQ++Y+ SYGQ   TGY T + PQ Y        TG Y +          S ++QS+Y
Sbjct: 60  TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 92  GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129
           G Q +YP YGQQPA                  P S++G Y   S     S+Y  PQ  GS
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178

Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           Y  QP          SY         Q SY QQ +Y  P  YGQQ+ Y   S  G     
Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238

Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
                 G+Y Q  S  S    S G   +  Q      G YGQ+  G  G G +    G  
Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPD 298

Query: 229 GGGYNRSSGGYEPRG--RGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD-----SEQDN 281
             G  R  GG++  G  RGG  GGRGGMG  +RGGFNK GGP D+G   D        ++
Sbjct: 299 NRG--RGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 356

Query: 282 SDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSF 341
           SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+ATVS+
Sbjct: 357 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 416

Query: 342 DDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RGGPMGR 394
           +DPP+AKAA++WFDGK+F G+ +KVS A ++   N  RGG   R GRG     RGGP G 
Sbjct: 417 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 476

Query: 395 GGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENMNFSWR 441
           GG GG     G  GG RGGFP  G         GGG  Q RAGDW+CPNP C N NF+WR
Sbjct: 477 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 536

Query: 442 NECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGRGGYDR 481
            ECNQCKAPKP+G        PG     GGPGG   G       G  G   RGGRGG DR
Sbjct: 537 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG-DR 595

Query: 482 GGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQDRRERP 525
           GG+R GRG DRGGF GGR GG               RGG  GPGKMD +GEHRQ+RR+RP
Sbjct: 596 GGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERRDRP 654

Query: 526 Y 526
           Y
Sbjct: 655 Y 655


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score =  458 bits (1178), Expect = e-129
 Identities = 297/666 (44%), Positives = 359/666 (53%), Gaps = 145/666 (21%)

Query: 1   MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
           MAS DY+      A Q Y AY  QP QGY+Q ++Q YGQQSY  Y Q TD        T+
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59

Query: 49  GYGQSSYS-SYGQ-----SQNTGYGTQSTPQGYGS------TGGYGS----------SQS 86
            YGQ++Y+ SYGQ       +TGY T + PQ Y        TG Y +          S +
Sbjct: 60  TYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYA 119

Query: 87  SQSSYGQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQP 125
           +QS+YG Q +YP YGQQPA                  P S++G Y   S     S+Y  P
Sbjct: 120 AQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYP 179

Query: 126 Q-SGSYSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
           Q  GSY  QP          SY         Q SY QQ +Y  P  YGQQ+ Y   S  G
Sbjct: 180 QVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239

Query: 169 GGGGGG-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGG 223
                      G+Y Q  S  S    S G   +  Q      G YGQ+  G  G G +  
Sbjct: 240 QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRS 299

Query: 224 GGGGGGGGYNRSSGGYEPRG--RGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD----- 276
             G    G  R  GG++  G  RGG  GGRGGMG  +RGGFNK GGP D+G   D     
Sbjct: 300 MSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPV 357

Query: 277 SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGE 336
              ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+
Sbjct: 358 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 417

Query: 337 ATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RG 389
           ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++   N  RGG   R GRG     RG
Sbjct: 418 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 477

Query: 390 GPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENM 436
           GP G GG GG     G  GG RGGFP  G         GGG  Q RAGDW+CPNP C N 
Sbjct: 478 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 537

Query: 437 NFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGR 476
           NF+WR ECNQCKAPKP+G        PG     GGPGG   G       G  G   RGGR
Sbjct: 538 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 597

Query: 477 GGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQD 520
           GG DRGG+R GRG DRGGF GGR GG               RGG  GPGKMD +GEHRQ+
Sbjct: 598 GG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQE 655

Query: 521 RRERPY 526
           RR+RPY
Sbjct: 656 RRDRPY 661


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score =  457 bits (1177), Expect = e-129
 Identities = 300/664 (45%), Positives = 360/664 (54%), Gaps = 146/664 (21%)

Query: 1   MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
           MAS DY+      A Q Y AY  QP QGY+Q ++Q YGQQSY  Y Q TD        T+
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59

Query: 49  GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91
            YGQ++Y+ SYGQ   TGY T + PQ Y        TG Y +          S ++QS+Y
Sbjct: 60  TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 92  GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129
           G Q +YP YGQQPA                  P S++G Y   S     S+Y  PQ  GS
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178

Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           Y  QP          SY         Q SY QQ +Y  P  YGQQ+ Y   S  G     
Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238

Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG----GRGRGGSGGG 224
                 G+Y Q  S  S    S G   +  Q      G YGQ+  G    G  R  SG  
Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPD 298

Query: 225 GGGGG-GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD-----SE 278
             G G GG++R  GG    GRGGGRGG G  G  +RGGFNK GGP D+G   D       
Sbjct: 299 NRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNKPGGPMDEGPDLDLGPPVDP 354

Query: 279 QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 338
            ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+AT
Sbjct: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414

Query: 339 VSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RGGP 391
           VS++DPP+AKAA++WFDGK+F G+ +KVS A ++   N  RGG   R GRG     RGGP
Sbjct: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474

Query: 392 MGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENMNF 438
            G GG GG     G  GG RGGFP  G         GGG  Q RAGDW+CPNP C N NF
Sbjct: 475 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534

Query: 439 SWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGRGG 478
           +WR ECNQCKAPKP+G        PG     GGPGG   G       G  G   RGGRGG
Sbjct: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594

Query: 479 YDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQDRR 522
            DRGG+R GRG DRGGF GGR GG               RGG  GPGKMD +GEHRQ+RR
Sbjct: 595 -DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERR 652

Query: 523 ERPY 526
           +RPY
Sbjct: 653 DRPY 656


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score =  407 bits (1046), Expect = e-113
 Identities = 267/522 (51%), Positives = 299/522 (57%), Gaps = 89/522 (17%)

Query: 12  QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69
           QSY  Y     QGY Q S      QSYSGY Q+TD+S YGQ  S YSSYGQSQ +GY   
Sbjct: 15  QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSQ-SGYS-- 64

Query: 70  STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
              Q YG     G     QSSY QQ  Y   GQQ    S SGS G   ++ SY QP  G 
Sbjct: 65  ---QSYG-----GYENQKQSSYSQQP-YNNQGQQQNMES-SGSQGG--RAPSYDQPDYG- 111

Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
                    QQ SY QQ  Y+  QG Y +Q+ Y+             +Y Q+Q S  S  
Sbjct: 112 ---------QQDSYDQQSGYDQHQGSYDEQSNYDQQHD---------SYSQNQQSYHS-- 151

Query: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248
                Y +  Q        YG+ +RG    GGS GGG        R  GGY+  GRG   
Sbjct: 152 -QRENYSHHTQDDRRDVSRYGEDNRG---YGGSQGGG--------RGRGGYDKDGRGPMT 199

Query: 249 GGRGGMGGSDRGGFNKFGGPRDQGSRHD--SEQDNSDNNTIFVQGLGENVTIESVADYFK 306
           G  GG    DRGGF  FGG RD G R D  SE DNSDNNTIFVQGLGE V+ + V ++FK
Sbjct: 200 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 255

Query: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366
           QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV
Sbjct: 256 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 315

Query: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426
           SFATRR +F RGGG+G G RGRGG  GRGG+        GRGG P          ++GDW
Sbjct: 316 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 358

Query: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483
            CPNP+C NMNF+ RN CNQC  P+P+   P GG   G   GG  G   RGGRGG DRGG
Sbjct: 359 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 417

Query: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521
           Y G   GG  GG R   GG  GDR G G G   S G +  DR
Sbjct: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459



 Score =  111 bits (277), Expect = 2e-24
 Identities = 86/224 (38%), Positives = 98/224 (43%), Gaps = 31/224 (13%)

Query: 52  QSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG 111
           + S  S G  +  GYG +   +G G  GG       +  YG   S  GYG      S+ G
Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGRGGRGG------DRGGYGGDRSGGGYG---GDRSSGG 435

Query: 112 SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS-YGQQQSYNPPQGYG--QQNQYNSSSGGG 168
            Y        YG  +SG       YGG +   YG  +      GYG  +   Y    GG 
Sbjct: 436 GYSGDRSGGGYGGDRSGG-----GYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGY 486

Query: 169 GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
           GG  GGG YG D+      GG  GGYG      GG  GGYG    G R RGG GG  GGG
Sbjct: 487 GGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGGG 538

Query: 229 GGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270
            G     SGGY     GGG GG RGG  G DRGG+  K GG  D
Sbjct: 539 SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 582



 Score =  106 bits (264), Expect = 6e-23
 Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%)

Query: 79  GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120
           GG G  +  +  Y  +  + G G  P       P+ + G+   + ++S            
Sbjct: 328 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 387

Query: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178
             S G  +   Y  +  Y G+    G +  Y   +  G      SS GG  G   GG YG
Sbjct: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447

Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236
            D+S    GG  GGGYG     G GG   GGYG  DRGG G G  GGG GG  GGY    
Sbjct: 448 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 505

Query: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272
           GGY  +  G GG RGG      RGG GG DRGG + +GG R  G
Sbjct: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 548



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%)

Query: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428
           +RGGG G  RGG G  RGG  G  RGGYGG   G GG RGG+    GG GG +  G    
Sbjct: 474 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 529

Query: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488
                                    G GG  GG   G  YG DR GG GG DR      G
Sbjct: 530 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 555

Query: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526
           G  GG RGG  GGDRGG+G GKM  R ++R D+R RPY
Sbjct: 556 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 592



 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 74/205 (36%), Positives = 81/205 (39%), Gaps = 48/205 (23%)

Query: 40  GYSQSTDTSGYG--QSSYSSY-GQSQNTGYGTQSTPQGYGST--GGYGSSQSSQSSYGQQ 94
           GY       GYG  +SS   Y G     GYG   +  GYG    GGYG  +         
Sbjct: 417 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG------- 469

Query: 95  SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154
               GYG         G YG       YG  + G       YGG +  YG          
Sbjct: 470 ----GYG-----GDRGGGYG--GDRGGYGGDRGG------GYGGDRGGYG---------- 502

Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG 214
            G +  Y    GG GG  GG  YG D+S    GG  GGG G     GG  SGGYG  DR 
Sbjct: 503 -GDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGGSG----YGGDRSGGYG-GDRS 554

Query: 215 GRGRGGSGGGG-GGGGGGYNRSSGG 238
           G G GG  GGG GG  GGY    GG
Sbjct: 555 GGGYGGDRGGGYGGDRGGYGGKMGG 579



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 100/373 (26%), Positives = 133/373 (35%), Gaps = 112/373 (30%)

Query: 4   NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58
           + Y QQ+   Q  G+Y  Q    Y QQ    Y Q   S +SQ  + S + Q      S Y
Sbjct: 114 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 170

Query: 59  GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115
           G+  N GY G+Q   +G G     G    + SS G +  +  +G  +   P + + S   
Sbjct: 171 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229

Query: 116 SSQSSSY------------------------------GQPQSGSYSQQPSYGGQQQSYGQ 145
           +S +++                               G+P    Y+ + +  G+ +    
Sbjct: 230 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT--GKPKGEAT 287

Query: 146 QQSYNPPQGYGQQNQYNSSS-------------------GGGGGGG--GGGNYGQDQSSM 184
               +PP      + ++                      GGG GGG  G G Y       
Sbjct: 288 VSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 347

Query: 185 SSGGGSGGG--------YGNQ------------------------DQSGGGGSGGYGQQD 212
             GG    G         GN                         D  G G  G  G + 
Sbjct: 348 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 407

Query: 213 RGGRG--RGG-----SGGGGGG---GGGGY--NRSSGGYEPRGRGGGRGG-RGGMGGSDR 259
           RGGRG  RGG     SGGG GG    GGGY  +RS GGY     GGG GG RGG  G DR
Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 467

Query: 260 GGFNKFGGPRDQG 272
           GG   +GG R  G
Sbjct: 468 GG--GYGGDRGGG 478



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%)

Query: 14  YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72
           YG   +  G G  + S   Y G +S  GY       GYG      YG  +  GYG     
Sbjct: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 477

Query: 73  QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
              G  GGYG  +             GYG         G YG       YG  + G    
Sbjct: 478 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 518

Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
           +  YGG +   G         GYG            GGG GG                GG
Sbjct: 519 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 564

Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218
           GYG      GG  GG        R R
Sbjct: 565 GYGGDRGGYGGKMGGRNDYRNDQRNR 590



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 91/376 (24%), Positives = 123/376 (32%), Gaps = 110/376 (29%)

Query: 4   NDYTQQATQSYGAYPTQPGQG-------------------YSQQSSQPYGQQSY---SGY 41
           + Y+QQ   + G        G                   Y QQS     Q SY   S Y
Sbjct: 76  SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135

Query: 42  SQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTG----GYGSSQSSQSSYGQQSSY 97
            Q  D+  Y Q+  S + Q +N  + TQ   +     G    GYG SQ      G    Y
Sbjct: 136 DQQHDS--YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRG---GY 190

Query: 98  PGYGQQPAPSSTSGSYG--------------SSSQSSSYGQPQSGSYSQQPSYGGQQQSY 143
              G+ P   S+ G  G              + + S S     +  + Q    G      
Sbjct: 191 DKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQV 250

Query: 144 GQ--QQ----SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS----------- 186
           G+  +Q      N   G    N Y     G   G    ++    S+ ++           
Sbjct: 251 GEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG 310

Query: 187 ----------------GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG 230
                           GGGSGG  G + + G  G GG+  Q RGG  + G         G
Sbjct: 311 NIIKVSFATRRPEFMRGGGSGG--GRRGRGGYRGRGGF--QGRGGDPKSGDWVCPNPSCG 366

Query: 231 GYN------------------RSSGG-YEPRGRGGGRG--GRGGMGGSDRGGF------N 263
             N                  R SGG +  RG GG RG  GRGG GG DRGG+       
Sbjct: 367 NMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGGYGGDRSGG 425

Query: 264 KFGGPRDQGSRHDSEQ 279
            +GG R  G  +  ++
Sbjct: 426 GYGGDRSSGGGYSGDR 441



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%)

Query: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420
           D +RGG  G+  GG G GG    GGYGG    GG GG   GG+    GG GG+
Sbjct: 525 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 576



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409
           D + G G  R G G GG  G GGYGG   G GG+ G
Sbjct: 544 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 578


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score =  404 bits (1038), Expect = e-112
 Identities = 264/522 (50%), Positives = 298/522 (57%), Gaps = 92/522 (17%)

Query: 12  QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69
           QSY  Y     QGY Q S      QSYSGY Q+TD+S YGQ  S YSSYGQS +  Y   
Sbjct: 15  QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSYSQSY--- 64

Query: 70  STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
                    GGY + +  QSSY QQ  Y   GQQ    S SGS G   ++ SY QP  G 
Sbjct: 65  ---------GGYENQK--QSSYSQQP-YNNQGQQQNMES-SGSQGG--RAPSYDQPDYG- 108

Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
                    QQ SY QQ  Y+  QG Y +Q+ Y+             +Y Q+Q S  S  
Sbjct: 109 ---------QQDSYDQQSGYDQHQGSYDEQSNYDQQHD---------SYSQNQQSYHS-- 148

Query: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248
                Y +  Q        YG+ +RG    GGS GGG        R  GGY+  GRG   
Sbjct: 149 -QRENYSHHTQDDRRDVSRYGEDNRG---YGGSQGGG--------RGRGGYDKDGRGPMT 196

Query: 249 GGRGGMGGSDRGGFNKFGGPRDQGSRHD--SEQDNSDNNTIFVQGLGENVTIESVADYFK 306
           G  GG    DRGGF  FGG RD G R D  SE DNSDNNTIFVQGLGE V+ + V ++FK
Sbjct: 197 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 252

Query: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366
           QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV
Sbjct: 253 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 312

Query: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426
           SFATRR +F RGGG+G G RGRGG  GRGG+        GRGG P          ++GDW
Sbjct: 313 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 355

Query: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483
            CPNP+C NMNF+ RN CNQC  P+P+   P GG   G   GG  G   RGGRGG DRGG
Sbjct: 356 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 414

Query: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521
           Y G   GG  GG R   GG  GDR G G G   S G +  DR
Sbjct: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456



 Score =  111 bits (277), Expect = 2e-24
 Identities = 86/224 (38%), Positives = 98/224 (43%), Gaps = 31/224 (13%)

Query: 52  QSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG 111
           + S  S G  +  GYG +   +G G  GG       +  YG   S  GYG      S+ G
Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGRGGRGG------DRGGYGGDRSGGGYG---GDRSSGG 432

Query: 112 SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS-YGQQQSYNPPQGYG--QQNQYNSSSGGG 168
            Y        YG  +SG       YGG +   YG  +      GYG  +   Y    GG 
Sbjct: 433 GYSGDRSGGGYGGDRSGG-----GYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGY 483

Query: 169 GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
           GG  GGG YG D+      GG  GGYG      GG  GGYG    G R RGG GG  GGG
Sbjct: 484 GGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGGG 535

Query: 229 GGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270
            G     SGGY     GGG GG RGG  G DRGG+  K GG  D
Sbjct: 536 SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 579



 Score =  106 bits (264), Expect = 6e-23
 Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%)

Query: 79  GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120
           GG G  +  +  Y  +  + G G  P       P+ + G+   + ++S            
Sbjct: 325 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384

Query: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178
             S G  +   Y  +  Y G+    G +  Y   +  G      SS GG  G   GG YG
Sbjct: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444

Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236
            D+S    GG  GGGYG     G GG   GGYG  DRGG G G  GGG GG  GGY    
Sbjct: 445 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 502

Query: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272
           GGY  +  G GG RGG      RGG GG DRGG + +GG R  G
Sbjct: 503 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 545



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%)

Query: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428
           +RGGG G  RGG G  RGG  G  RGGYGG   G GG RGG+    GG GG +  G    
Sbjct: 471 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 526

Query: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488
                                    G GG  GG   G  YG DR GG GG DR      G
Sbjct: 527 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 552

Query: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526
           G  GG RGG  GGDRGG+G GKM  R ++R D+R RPY
Sbjct: 553 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 589



 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 74/205 (36%), Positives = 81/205 (39%), Gaps = 48/205 (23%)

Query: 40  GYSQSTDTSGYG--QSSYSSY-GQSQNTGYGTQSTPQGYGST--GGYGSSQSSQSSYGQQ 94
           GY       GYG  +SS   Y G     GYG   +  GYG    GGYG  +         
Sbjct: 414 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG------- 466

Query: 95  SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154
               GYG         G YG       YG  + G       YGG +  YG          
Sbjct: 467 ----GYG-----GDRGGGYG--GDRGGYGGDRGG------GYGGDRGGYG---------- 499

Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG 214
            G +  Y    GG GG  GG  YG D+S    GG  GGG G     GG  SGGYG  DR 
Sbjct: 500 -GDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGGSG----YGGDRSGGYG-GDRS 551

Query: 215 GRGRGGSGGGG-GGGGGGYNRSSGG 238
           G G GG  GGG GG  GGY    GG
Sbjct: 552 GGGYGGDRGGGYGGDRGGYGGKMGG 576



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 100/373 (26%), Positives = 133/373 (35%), Gaps = 112/373 (30%)

Query: 4   NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58
           + Y QQ+   Q  G+Y  Q    Y QQ    Y Q   S +SQ  + S + Q      S Y
Sbjct: 111 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 167

Query: 59  GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115
           G+  N GY G+Q   +G G     G    + SS G +  +  +G  +   P + + S   
Sbjct: 168 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226

Query: 116 SSQSSSY------------------------------GQPQSGSYSQQPSYGGQQQSYGQ 145
           +S +++                               G+P    Y+ + +  G+ +    
Sbjct: 227 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT--GKPKGEAT 284

Query: 146 QQSYNPPQGYGQQNQYNSSS-------------------GGGGGGG--GGGNYGQDQSSM 184
               +PP      + ++                      GGG GGG  G G Y       
Sbjct: 285 VSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 344

Query: 185 SSGGGSGGG--------YGNQ------------------------DQSGGGGSGGYGQQD 212
             GG    G         GN                         D  G G  G  G + 
Sbjct: 345 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 404

Query: 213 RGGRG--RGG-----SGGGGGG---GGGGY--NRSSGGYEPRGRGGGRGG-RGGMGGSDR 259
           RGGRG  RGG     SGGG GG    GGGY  +RS GGY     GGG GG RGG  G DR
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 464

Query: 260 GGFNKFGGPRDQG 272
           GG   +GG R  G
Sbjct: 465 GG--GYGGDRGGG 475



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%)

Query: 14  YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72
           YG   +  G G  + S   Y G +S  GY       GYG      YG  +  GYG     
Sbjct: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474

Query: 73  QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
              G  GGYG  +             GYG         G YG       YG  + G    
Sbjct: 475 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 515

Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
           +  YGG +   G         GYG            GGG GG                GG
Sbjct: 516 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 561

Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218
           GYG      GG  GG        R R
Sbjct: 562 GYGGDRGGYGGKMGGRNDYRNDQRNR 587



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%)

Query: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420
           D +RGG  G+  GG G GG    GGYGG    GG GG   GG+    GG GG+
Sbjct: 522 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 573



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)

Query: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409
           D + G G  R G G GG  G GGYGG   G GG+ G
Sbjct: 541 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 575


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score =  152 bits (384), Expect = 7e-37
 Identities = 122/333 (36%), Positives = 145/333 (43%), Gaps = 86/333 (25%)

Query: 1   MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
           MAS DY+      A Q Y AY  QP QGY+Q ++Q YGQQSY  Y Q TD        T+
Sbjct: 1   MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59

Query: 49  GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91
            YGQ++Y+ SYGQ   TGY T + PQ Y        TG Y +          S ++QS+Y
Sbjct: 60  TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 92  GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129
           G Q +YP YGQQPA                  P S++G Y   S     S+Y  PQ  GS
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178

Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           Y  QP          SY         Q SY QQ +Y  P  YGQQ+ Y   S  G     
Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238

Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
                 G+Y Q  S  S    S G   +  Q      G YGQ+             GG  
Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES------------GGFS 286

Query: 229 GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
           G G NRS  G + RGRG G   RGGM    RGG
Sbjct: 287 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGG 319



 Score =  103 bits (257), Expect = 4e-22
 Identities = 100/243 (41%), Positives = 121/243 (49%), Gaps = 57/243 (23%)

Query: 7   TQQATQSYGAYP-----TQPGQGYSQ-QSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60
           TQ A  +YG  P     T+P  G    ++SQP  Q S  GY+Q +   GYGQS+YS Y Q
Sbjct: 120 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQP--QSSTGGYNQPS--LGYGQSNYS-YPQ 174

Query: 61  SQNTGYGTQ--STPQGYGSTGGYGSSQSS---QSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
              + Y  Q  + P  Y  T  Y S+Q +   QSSY QQ++Y     QP+      SYG 
Sbjct: 175 VPGS-YPMQPVTAPPSYPPTS-YSSTQPTSYDQSSYSQQNTYG----QPSSYGQQSSYG- 227

Query: 116 SSQSSSYGQ-------PQSGSYSQQPS-YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167
             Q SSYGQ       PQ+GSYSQ PS Y  Q  SYGQQ S+       +Q+  +S    
Sbjct: 228 --QQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSF-------RQDHPSSM--- 275

Query: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-GYGQQDRGGRGRGGSGGGGG 226
                  G YGQ+     SGG SG G  N+  SG    G G G  DRGG  RGG GGG G
Sbjct: 276 -------GVYGQE-----SGGFSGPG-ENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG 322

Query: 227 GGG 229
           G G
Sbjct: 323 GMG 325



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 97/395 (24%), Positives = 140/395 (35%), Gaps = 79/395 (20%)

Query: 38  YSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSY 97
           YS YSQ+       Q  YS+Y      GY    T Q YG        Q S  +YGQ +  
Sbjct: 6   YSTYSQAA-----AQQGYSAYTAQPTQGYA--QTTQAYG--------QQSYGTYGQPTDV 50

Query: 98  PGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQ 157
             Y Q    + T+ +YG ++ ++SYGQP +G Y+   +     Q+Y Q     P QGY  
Sbjct: 51  -SYTQ----AQTTATYGQTAYATSYGQPPTG-YTTPTA----PQAYSQ-----PVQGY-- 93

Query: 158 QNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS---GGGYGNQDQSGGGGSGGYGQQDRG 214
                          G G Y    +++++   S      YG Q          YGQQ   
Sbjct: 94  ---------------GTGAYDTTTATVTTTQASYAAQSAYGTQP-----AYPAYGQQPAA 133

Query: 215 GRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG-S 273
                   G           S+GGY     G G+                   P     +
Sbjct: 134 TAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193

Query: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333
            + S Q  S + + + Q      T    + Y +Q    + +    QP  +     +TG  
Sbjct: 194 SYSSTQPTSYDQSSYSQ----QNTYGQPSSYGQQSSYGQQSSYGQQPPTSY--PPQTG-- 245

Query: 334 KGEATVSFDDPPSAKAAIDWFDGKEFS---GNPIKVSFATRRADFNRGGGNGRG-GRGRG 389
                 S+   PS  +      G++ S    +P  +    + +    GG +G G  R   
Sbjct: 246 ------SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES----GGFSGPGENRSMS 295

Query: 390 GPMGRG-GYGGGGSGGGGRGGFPSGGGGGGGQQRA 423
           GP  RG G GG   GG  RGG   G GG G Q  +
Sbjct: 296 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGLQSES 330



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 28/52 (53%), Positives = 28/52 (53%), Gaps = 4/52 (7%)

Query: 458 GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGG-DRGGF-RGGRGGGDRGGFG 507
           G  G   GG  G        G D  G RGRGG DRGG  RGGRGGG RGG G
Sbjct: 276 GVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGG-RGGMG 325



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 25/45 (55%), Positives = 26/45 (57%), Gaps = 3/45 (6%)

Query: 456 GGGPGGSHMGGNYGDDRRG-GRGGYDRGGYRGRGGDRGGFRGGRG 499
           GG  G        G D RG GRGG+DRGG   RGG RGG RGG G
Sbjct: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGM-SRGG-RGGGRGGMG 325


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score =  148 bits (373), Expect = 1e-35
 Identities = 160/575 (27%), Positives = 226/575 (39%), Gaps = 83/575 (14%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQ-PYGQQSYSGYSQ----STDTSGYGQSSYSS 57
            S+ + Q  ++S  +   Q G G SQ S    YG +  SG+ Q    S  ++G+GQ  Y S
Sbjct: 528  SSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQ--YGS 585

Query: 58   YGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS---------------YPGYGQ 102
             G  Q++G+G   +  G  S  G   S+S QSSYGQ SS                 G+GQ
Sbjct: 586  -GSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQ 644

Query: 103  QPAPSSTS---GSYGS-SSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158
              + SS S   G YGS S QSS +GQ  SGS        GQ   +GQ +S +    YGQ 
Sbjct: 645  HGSGSSQSTGFGQYGSGSGQSSGFGQHVSGS--------GQSSGFGQHESRSGHSSYGQH 696

Query: 159  NQYNSSSGG----GGGGGGGGNYGQDQSSM---------SSGGGSGGGYGNQDQSGGGGS 205
               +S S G    G   G    +GQ + S           SG G   G+G Q  SG G S
Sbjct: 697  GFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFG-QHGSGSGQS 755

Query: 206  GGYGQ-QDRGGRGRGGSGGGGGGGGGGY----NRSSGGYEPRGRGGGRG---GRGGMGGS 257
             G+GQ + R G+   G    G     GY    +R + G+   G G  +    G+ G G  
Sbjct: 756  SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSG 815

Query: 258  DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKT 317
               GF + G    Q S     +  S  ++    G G +          +  G  +    +
Sbjct: 816  QSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSS----------QSSGYGQHGSSS 865

Query: 318  GQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSG------NPIKVSFATR 371
            GQ          +G+  G          S+          ++SG         + S+   
Sbjct: 866  GQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQH 925

Query: 372  RADFNRGGGNGRGGRGRGGPMGRGGY--GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429
             +  ++  G G+ G   G   G G +  G G S G G+ G  SG   G GQ  +G  K  
Sbjct: 926  GSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGK-S 984

Query: 430  NPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYG-DDRRGGRGGYDRGGYRGRG 488
            +   ++ + S ++   Q  +      G G  GS  G   G    R   G Y   G  G G
Sbjct: 985  SGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSG 1044

Query: 489  GDR-GGF-RGGRGGGDRGGFGP----GKMDSRGEH 517
             D+  GF + G G G   GFG      +  S G+H
Sbjct: 1045 SDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQH 1079



 Score =  144 bits (364), Expect = 2e-34
 Identities = 159/584 (27%), Positives = 225/584 (38%), Gaps = 107/584 (18%)

Query: 11   TQSYGAYPTQPGQG-YSQQSSQPYGQQSYSGYSQ--STDTSGYGQ--------SSYSSYG 59
            +  +G + ++ GQ  Y Q SS   G    SGY Q  S  TSG+GQ        + +  YG
Sbjct: 603  SSGFGQHESRSGQSSYGQHSS---GSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG 659

Query: 60   QS--QNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQ----SSYPGYGQQPAPSSTSGSY 113
                Q++G+G   +  G  S  G   S+S  SSYGQ     S   GYGQ  + S  +  +
Sbjct: 660  SGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGF 719

Query: 114  G----SSSQSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSS 164
            G    SS QSSS+GQ  SGS     + Q  S  GQ   +GQ +S +    YGQ +  +S 
Sbjct: 720  GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 779

Query: 165  SGGGGGGG-----GGGNYGQDQSSMS------SGGGSGGGYGNQDQSGGGGSGGYGQQD- 212
            S G G  G     G G +G   S  +      SG G   G+G Q  SG G S G+GQ + 
Sbjct: 780  SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFG-QHGSGSGQSSGFGQHES 838

Query: 213  ----------------RGGRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGG 253
                              G G+ GS  G   G G +  SSG   G+   G G G+    G
Sbjct: 839  RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFG 898

Query: 254  MGGSDRGGFNKFG-----------GPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
              G+  G ++ FG           G    GS   S      +++    G G++ +    +
Sbjct: 899  QHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQS 958

Query: 303  DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
              F Q G       +G    + +   E+G  K      F    S  +  ++  G+  SG+
Sbjct: 959  SGFGQHG-------SGSGQSSGFGQHESGSGKSS---GFGQHESRSSQSNY--GQHGSGS 1006

Query: 363  PIKVSFATRRADFNR--GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420
                 +    +   +  G G  R   G+    G+ G G   S G G+ G  SG   G GQ
Sbjct: 1007 SQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQ 1066

Query: 421  QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG--GNYGDDRRGGRGG 478
              +               S ++   Q  +      G G  GS+ G    +G  R G    
Sbjct: 1067 YESR--------------SRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQS 1112

Query: 479  YDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGK----MDSRGEH 517
               G Y    G   GF + G G G   GF   +      S G+H
Sbjct: 1113 SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQH 1156



 Score =  122 bits (306), Expect = 8e-28
 Identities = 144/566 (25%), Positives = 207/566 (36%), Gaps = 84/566 (14%)

Query: 20  QPGQGYSQQSSQPYGQQSYSG---YSQSTDTSGYGQSSYSSYGQSQNTGY---------- 66
           Q G G SQ  S   GQ  Y     +S S+ ++ + +      G SQ+T +          
Sbjct: 382 QYGSGGSQSCSN--GQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQS 439

Query: 67  -GTQSTPQGYGSTGGYGSSQSSQS-SYGQQSSYPG----YGQQPAPSSTSGSYGS----S 116
            G +    G G T G   S SSQS  Y Q  S  G    +GQ  + S  S  +G     S
Sbjct: 440 SGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGS 499

Query: 117 SQSSSYGQP-----QSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG 171
            QSS +GQ      QS  + Q  S  GQ   +GQ +S +    YGQ    +S S G G  
Sbjct: 500 GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQY 559

Query: 172 GGGGNYGQDQSSMSSGGGSG-GGYGN---------QDQSGGGGSGGYGQQD-RGGRGRGG 220
           G     G  Q  + SG  +G G YG+         Q  SG G S G+GQ + R G+   G
Sbjct: 560 GSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 619

Query: 221 SGGGGGGGGGGY----NRSSGGYEPRGRGGGRG---GRGGMGGSDRGGFNKFGGPRDQGS 273
               G     GY    +R + G+   G G  +    G+ G G     GF +      Q S
Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSS 679

Query: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333
                +  S +++    G G +          +  G  +    +GQ      +     +L
Sbjct: 680 GFGQHESRSGHSSYGQHGFGSS----------QSSGYGQHGSSSGQT-----SGFGQHEL 724

Query: 334 KGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRG-------GGNGRGGR 386
               + SF    S       F G+  SG+     F    +   +        G +   G 
Sbjct: 725 SSGQSSSFGQHGSGSGQSSGF-GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY 783

Query: 387 GRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ 446
           G+ G     G+G  GSG     GF   G G G  Q AG  +  + + ++  F      + 
Sbjct: 784 GQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSG--QSAGFGQHGSGSGQSSGFGQHESRSH 841

Query: 447 CKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGG 505
             +    G G      +  G +G    G   G+  G +R   G   GF + G G G   G
Sbjct: 842 QSSYGQHGSGSSQSSGY--GQHGSSS-GQTSGF--GQHRSSSGQYSGFGQHGSGSGQSSG 896

Query: 506 FGP-----GKMDSRGEHRQDRRERPY 526
           FG      G+    G+H     +  Y
Sbjct: 897 FGQHGTGSGQYSGFGQHESRSHQSSY 922



 Score =  121 bits (304), Expect = 1e-27
 Identities = 139/527 (26%), Positives = 188/527 (35%), Gaps = 90/527 (17%)

Query: 7    TQQATQSYGAYPTQPGQ--GYSQQSSQP---YGQQSYSGYSQSTDTSGYGQSSYSSYG-- 59
            ++    SYG + +   Q  GY Q  S+    +GQ   SG SQST    YG  S  S G  
Sbjct: 763  SRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHG-SGSSQSTGFGQYGSGSGQSAGFG 821

Query: 60   -----QSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSSTS 110
                   Q++G+G   +     S G +GS  S  S YGQ  S      G+GQ     S+S
Sbjct: 822  QHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQH---RSSS 878

Query: 111  GSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGG- 169
            G Y    Q  S G  QS  + Q  +  GQ   +GQ +S +    YGQ    +S S G G 
Sbjct: 879  GQYSGFGQHGS-GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ 937

Query: 170  -GGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
             G   G  +G  Q    SG  SG G   Q  SG G S G+GQ +       GSG   G G
Sbjct: 938  HGSSSGQTFGFGQHRSGSGQSSGFG---QHGSGSGQSSGFGQHE------SGSGKSSGFG 988

Query: 229  GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288
                  S   Y   G G  +    G  GS  G    FG  R    ++             
Sbjct: 989  QHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQY------------- 1035

Query: 289  VQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAK 348
              G G++ +    +  F Q G       TG    + +   E+   +              
Sbjct: 1036 -SGFGQHGSGSDQSSGFGQHG-------TGSGQSSGFGQYESRSRQSSY----------- 1076

Query: 349  AAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRG 408
                   G+  SG+     +    ++  +  G G+   G G   G G YG G     G G
Sbjct: 1077 -------GQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFG 1129

Query: 409  GFPSGGGGGGG----QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHM 464
               SG G   G    + R+G              S  + C Q ++      G GP  S  
Sbjct: 1130 QHGSGTGKSSGFAQHEYRSGQSSYGQ---HGTGSSQSSGCGQHES------GSGPTTS-- 1178

Query: 465  GGNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGK 510
               +G    G       G +    G   GF + G G G   G G G+
Sbjct: 1179 ---FGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222



 Score =  114 bits (286), Expect = 2e-25
 Identities = 170/641 (26%), Positives = 228/641 (35%), Gaps = 140/641 (21%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ-----SSYSS 57
            S+ + Q  ++S+ +   Q G G SQ S   YGQ      S S  TSG+GQ       YS 
Sbjct: 830  SSGFGQHESRSHQSSYGQHGSGSSQSSG--YGQHG----SSSGQTSGFGQHRSSSGQYSG 883

Query: 58   YGQ-----SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSS 108
            +GQ      Q++G+G   T  G  S  G   S+S QSSYGQ  S      GYGQ  + S 
Sbjct: 884  FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 943

Query: 109  TSGSYGS----SSQSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159
             +  +G     S QSS +GQ  SGS     + Q  S  G+   +GQ +S +    YGQ  
Sbjct: 944  QTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHG 1003

Query: 160  QYNSSSGGGGGGGGG--------------GNY--------GQDQSS----MSSGGGSGGG 193
              +S S G G  G                G Y        G DQSS      +G G   G
Sbjct: 1004 SGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSG 1063

Query: 194  YGN-----------QDQSGGGGSGGYGQ------------QDRGGRGRG------GSGGG 224
            +G            Q  SG   S GYGQ            Q R G G+       GSG G
Sbjct: 1064 FGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG 1123

Query: 225  GGGG----GGGYNRSSGGYEPRGRGG----GRGGRGGMGGSDRGGFNKFGGPRDQGSRHD 276
               G    G G  +SSG  +   R G    G+ G G    S  G      GP     +H 
Sbjct: 1124 QSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHV 1183

Query: 277  SEQDN----------SDNNTIFVQ-----------GLGENVTIESVADYFKQIGI----- 310
            S  DN          S  +T F Q           G GE+  +ES +    +        
Sbjct: 1184 SGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQT 1243

Query: 311  IKTNK--KTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA---IDWFDGKEFSGNPIK 365
            I T +  ++GQ        R T + +   + + D    +K +    +    +  S  P  
Sbjct: 1244 INTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKS 1303

Query: 366  VSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGD 425
             S   RR     G    RG   R G  G G     GS   GR  F S       +  +G 
Sbjct: 1304 GSTVRRRQGTTHGQ---RGDTTRHGHSGHGQSTQTGSRTSGRQRF-SHSDATDSEVHSGV 1359

Query: 426  WKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR 485
               P+            E    +A    G             YG  + G   G+   G+ 
Sbjct: 1360 SHRPHS----------QEQTHSQAGSQHGESESTVHERHETTYG--QTGEATGHGHSGH- 1406

Query: 486  GRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526
            G+   RG    GR G         ++ S G HR   +E+ +
Sbjct: 1407 GQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTH 1447



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 120/533 (22%), Positives = 189/533 (35%), Gaps = 59/533 (11%)

Query: 2   ASNDYTQQATQSYGAYPTQPGQGYSQQS-SQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60
           +S +  ++  +S+ +   + G+ Y   S S  + ++ + G S   +TSG+  +S  S  +
Sbjct: 200 SSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIR 259

Query: 61  SQNTGY--------GTQSTPQGYGSTGGYGSSQSSQSS-----YGQQSSYPGYGQQPAPS 107
            Q  G         G +S   GY ++ G G  Q++ SS     +G Q +   Y Q    S
Sbjct: 260 EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQS 319

Query: 108 STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167
              G  G    S                 GGQ    GQ +S    Q Y Q+      +G 
Sbjct: 320 GIKGGQGHGCVS-----------------GGQPSGCGQPESNPCSQSYSQRGYGARENGQ 362

Query: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227
               GG    G  QSS     GSGG      QS   G   YG   R       +      
Sbjct: 363 PQNCGGQWRTGSSQSSCCGQYGSGG-----SQSCSNGQHEYGSCGRFSNSSSSNEFSKCD 417

Query: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG--GFNKFGGPRDQGSRHDSEQDNSDNN 285
             G  +  S  +E  G G  +       G ++   G  +  G  +  S      D   ++
Sbjct: 418 QYGSGSSQSTSFEQHGTGLSQS-----SGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSS 472

Query: 286 TIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPP 345
           +    G G++ +    +  F Q G       +GQ         + G + G+++  F    
Sbjct: 473 SGKTSGFGQHGSGSGQSSGFGQCG-----SGSGQSS----GFGQHGSVSGQSS-GFGQHG 522

Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405
           S       F   E      + S+    +  ++  G G+ G       G+ G G G S G 
Sbjct: 523 SVSGQSSGFGQHESRSR--QSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGF 580

Query: 406 GRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG 465
           G+ G  SG   G GQ  +G  +  +   ++ + S ++   Q  +      G G  GS   
Sbjct: 581 GQYGSGSGQSSGFGQHGSGSGQ-SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQT 639

Query: 466 GNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGKMDSRGEH 517
             +G    G       G Y    G   GF +   G G   GF  G+ +SR  H
Sbjct: 640 SGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF--GQHESRSGH 690



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 122/514 (23%), Positives = 175/514 (34%), Gaps = 64/514 (12%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85
           +Q+ SQ    +S  G+S S     +G SS     +  N  + + S   G     G GS+ 
Sbjct: 173 NQEGSQKRYHRSSCGHSWSGGKDRHGSSSVE-LRERINKSHISPSRESGEEYESGSGSNS 231

Query: 86  SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145
             +          G+G       TSG   +S+QS    Q    S S     G +  + G 
Sbjct: 232 WERK---------GHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACG- 281

Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG--GGSGGGYGNQDQSGGG 203
              Y+   G G+    +SS      GG G  +   QS   SG  GG G G  +  Q  G 
Sbjct: 282 ---YSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGC 338

Query: 204 G-------SGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS--GGYEPRGRGGGRGGRGGM 254
           G       S  Y Q+  G R  G     GG    G ++SS  G Y   G GG +    G 
Sbjct: 339 GQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQY---GSGGSQSCSNGQ 395

Query: 255 GGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTN 314
                 G        ++ S+ D     S  +T F Q    + T  S +  F+Q  +  + 
Sbjct: 396 HEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQ----HGTGLSQSSGFEQ-HVCGSG 450

Query: 315 KKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRAD 374
           +  GQ            +     ++ +D   S+      F G+  SG+            
Sbjct: 451 QTCGQH-----------ESTSSQSLGYDQHGSSSGKTSGF-GQHGSGS------------ 486

Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGG--GGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPT 432
             +  G G+ G G G   G G +G   G S G G+ G  SG   G GQ  +   +     
Sbjct: 487 -GQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQ 545

Query: 433 CENMNFSWRNECNQCKAPKPDGPGG---GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGG 489
                 S  +   Q  + +  G G    G G S   G YG       G    G   G+  
Sbjct: 546 -HGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSS 604

Query: 490 DRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRE 523
             G      G    G    G   S G  +   R+
Sbjct: 605 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ 638



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 74/288 (25%), Positives = 109/288 (37%), Gaps = 48/288 (16%)

Query: 9    QATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT 68
            Q+TQ       + G G+S+ S      + +SG S +     YGQ+  S +G+S +  +G 
Sbjct: 2089 QSTQRGSRTAGRRGSGHSESSDS----EVHSGVSHTHSGHTYGQAR-SQHGESGSAIHGR 2143

Query: 69   QSTPQG-------YGSTGGYGSSQSSQSSYGQQ-SSYPGYGQQPAPSSTSGSYGSSSQS- 119
            Q T  G       +G +G   S+Q+   + G+Q SS+         S  S ++   + S 
Sbjct: 2144 QGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQ 2203

Query: 120  --SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
              S +GQ  S  + +Q +  GQ     +   Y    GYGQ  Q  S + G  G G   + 
Sbjct: 2204 AGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHY----GYGQSTQRGSRTTGRRGSGHSESS 2259

Query: 178  GQDQSSMSSGGGSG---GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG-----G 229
              +  S  S   SG   G  G+Q +  G    G  +   G  G     G  G G     G
Sbjct: 2260 DSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTG 2319

Query: 230  GGYNRSS--------------------GGYEPRGRGGGRGGRGGMGGS 257
               +R+S                    G Y P     G  G G  GGS
Sbjct: 2320 SRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGS 2367



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 118/572 (20%), Positives = 192/572 (33%), Gaps = 96/572 (16%)

Query: 26   SQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-----------SSYGQSQN----------- 63
            +Q  S+  G++  SG+S+ +D+ GY   S+           S +G+S++           
Sbjct: 1714 TQTGSRTTGRRG-SGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772

Query: 64   -TGYGTQSTPQGYGSTGGYGS-----SQSSQSSYGQQSSYPGYGQQP-APSSTSGSYGSS 116
             TG  T+    G+G +   GS       S  S Y     + G+ Q+P +   T G  GS 
Sbjct: 1773 QTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQ 1832

Query: 117  SQSS----------SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG 166
               S          ++GQ    S   Q  +G   QS G   +     G+ + +     SG
Sbjct: 1833 HGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQS-GSSTTGRRRSGHSESSDSEVHSG 1891

Query: 167  GGGGGGG------GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGY----GQQDRGGR 216
            G     G         +G+ +S++     +  G        G  S G     G +  G R
Sbjct: 1892 GSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRR 1951

Query: 217  GRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG------------------------RGGRG 252
            G G S      G  G + +  G+   G+ G                         R G  
Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSGH-THGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHS 2010

Query: 253  GMGGSDRGGFNKFGGPRDQGSRHDSEQDN----SDNNTIFVQGLGENVTIESVADYFKQI 308
            G G S + G ++  G R  G    S+ +     S  ++    G   +   ES +   ++ 
Sbjct: 2011 GHGQSTQRG-SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERH 2069

Query: 309  GIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSF 368
            G   T+ +TG    + ++       +G  T        ++++    D +  SG     S 
Sbjct: 2070 G--TTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESS----DSEVHSGVSHTHSG 2123

Query: 369  ATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC 428
             T     ++ G +G    GR G +          G  G G     G    G+QR+   + 
Sbjct: 2124 HTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSES 2183

Query: 429  PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG---GNYGDDRRGGRGGYDRGGYR 485
             +    +      +     +A    G  G  G    G   G  GD  R    GY      
Sbjct: 2184 SDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGY------ 2237

Query: 486  GRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
            G+   RG    GR G         ++ S G H
Sbjct: 2238 GQSTQRGSRTTGRRGSGHSESSDSEVHSWGSH 2269



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 50/353 (14%)

Query: 19   TQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-----------SSYGQSQNTGYG 67
            +Q GQG S Q+     ++  S  S+++D+  + + S+           S Y +S +T   
Sbjct: 1250 SQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRR 1309

Query: 68   TQSTPQGY-GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126
             Q T  G  G T  +G S   QS+                S TSG    S   ++  +  
Sbjct: 1310 RQGTTHGQRGDTTRHGHSGHGQSTQ-------------TGSRTSGRQRFSHSDATDSEVH 1356

Query: 127  SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD-QSSMS 185
            SG  S +P    Q  S    Q         ++++      G   G G   +GQ  Q    
Sbjct: 1357 SG-VSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSR 1415

Query: 186  SGGGSGGGYG----------------NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGG 229
            + G  G G+                 +Q+Q+ G     +G+      GR G+  G  G  
Sbjct: 1416 TTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDT 1475

Query: 230  GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFV 289
              +     G   + RG    GR G G S+        G     S H   Q  S +     
Sbjct: 1476 TRHAHYHHGKSTQ-RGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQH----- 1529

Query: 290  QGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 342
             G  E++  +       Q G    +  +G         R TG+ +   + S D
Sbjct: 1530 -GESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTD 1581



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 63/305 (20%), Positives = 111/305 (36%), Gaps = 35/305 (11%)

Query: 6    YTQQATQSYGAYPTQPGQGYS---QQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQ 62
            ++Q+ T S     +Q G+  S   ++    YGQ   +G +     SG+GQS+      + 
Sbjct: 1364 HSQEQTHSQAG--SQHGESESTVHERHETTYGQ---TGEATGHGHSGHGQSTQRGSRTTG 1418

Query: 63   NTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY 122
              G G   +      +GG    QS + ++GQ  S  G            ++G +  ++ +
Sbjct: 1419 RRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRH 1478

Query: 123  GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
                 G  +Q+ S    ++  G  +S +     G  + ++    G   G  G  +G+ +S
Sbjct: 1479 AHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHS----GHTHGQSGSQHGESES 1534

Query: 183  SM---------SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG------ 227
             +          +G  +   Y   +Q+   GS   G+Q         S    GG      
Sbjct: 1535 IIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHS 1594

Query: 228  -----GGGGYNRSSGGYEPRGRGGGRGGRGG--MGGSDRG-GFNKFGGPRDQGSRHDSEQ 279
                 G  G       +    R G   G+ G   G S  G G +   G R  G +  S  
Sbjct: 1595 REHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHS 1654

Query: 280  DNSDN 284
            ++SD+
Sbjct: 1655 ESSDS 1659


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score =  139 bits (350), Expect = 6e-33
 Identities = 150/509 (29%), Positives = 193/509 (37%), Gaps = 52/509 (10%)

Query: 22   GQGYSQQSSQ-PYGQQSYSGYSQSTDT--SGYGQSSYSSYGQS---QNTGYGTQSTPQGY 75
            G G  Q SS  PY  +S SG+S S     SG G SS   + +S   Q++GYG   +  G+
Sbjct: 1015 GSGSGQSSSYGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 1072

Query: 76   GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQP 134
             ST G   S S     GQ SS   +G     SS+ G +GS SSQSS YG+  SGS  Q P
Sbjct: 1073 SSTHGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSP 1126

Query: 135  SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194
             +G  Q+  G +QS  P  G        SSS G  G G G + G      SSG  S    
Sbjct: 1127 GHG--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS--- 1179

Query: 195  GNQDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGG 253
             +Q  SG G S GYGQ   R G+   G   G   G   +    G    +  G GR G G 
Sbjct: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239

Query: 254  MGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT 313
                 RG      G      +H S    S +   +    G +        +    G    
Sbjct: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF---GQHESGSGHSSA 1296

Query: 314  NKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRA 373
              + G    +  +  + G   G+++ +FD   S+      + G   SG+     +    A
Sbjct: 1297 YSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGA 1354

Query: 374  DFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431
               +    GR G G G     G+ G G G S   GR G  SG   G G   +  W+    
Sbjct: 1355 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQ---- 1410

Query: 432  TCENMNFSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGG 489
                      + C Q       G G G   S+   G   G   RG R G   G     G 
Sbjct: 1411 ---------SSGCTQ------HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 1455

Query: 490  DRGGFRGGRGGGDRG-GFGPGKMDSRGEH 517
               G R   G G  G G G     SRG H
Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484



 Score =  136 bits (343), Expect = 4e-32
 Identities = 150/540 (27%), Positives = 214/540 (39%), Gaps = 75/540 (13%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61
            S+ + +Q + S G  P++   G     S  +GQ   SG  +S+    Y  +S +SS    
Sbjct: 2169 SSGHGRQGSGS-GHSPSRGRHGSGSGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 2226

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119
              +G G  S    +GS  G+  SQ    S+ GQ S++   G     SS+ G +GS SSQS
Sbjct: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286

Query: 120  SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178
            SSYGQ  SGS  Q PS G      G   SY     +G  + ++SSSG  G G G    +G
Sbjct: 2287 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 2342

Query: 179  QDQSS--MSSG---GGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN 233
              +SS   SSG    GSG G+ +  +  G  SG   + +R G   G S   G  G G  +
Sbjct: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG--S 2400

Query: 234  RSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFG---------GPRDQGSRHDSEQ 279
            R S G+   G G G+      GR G G      ++ +G         GP + GS H S  
Sbjct: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460

Query: 280  DNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATV 339
             + ++ +    G G++                      G    +  T  + G   G++  
Sbjct: 2461 GHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSTSGQS-- 2496

Query: 340  SFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRGGY 397
            S      A +      G+  SG+     +  + +   +  G+G+ G G R  P  GR G 
Sbjct: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556

Query: 398  GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGG 457
            G G S   G+ G   G   G G   +        + ++ ++S              G G 
Sbjct: 2557 GSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHG----------SGSGH 2599

Query: 458  GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
              G    G   G   RG R G   G     G    G R   G G R G G G+  SRG H
Sbjct: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-RQGSGSGQSPSRGRH 2658



 Score =  133 bits (335), Expect = 3e-31
 Identities = 153/542 (28%), Positives = 211/542 (38%), Gaps = 79/542 (14%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61
            S+ + +Q + S G  P++   G     S  +GQ   SG  +S+    Y  +S +SS    
Sbjct: 1699 SSGHGRQGSGS-GQSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 1756

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119
              +G G  S    +GS  G+  SQ    S+ GQ S++   G     SS+ G +GS SSQS
Sbjct: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816

Query: 120  SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178
            SSYGQ  SGS  Q PS G      G   SY     +G  + ++SSSG  G G G    +G
Sbjct: 1817 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 1872

Query: 179  QDQSS--MSSG---GGSGGGY----------------GNQDQSGGGGSGGYGQQDRGGRG 217
              +SS   SSG    GSG G+                G Q  S  G S  YGQ   G R 
Sbjct: 1873 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQ 1932

Query: 218  RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDS 277
              G G  G G G   + S G +   G G G+    G  GS   G++   GP + GS H S
Sbjct: 1933 SLGHGQHGSGSGQSPSPSRGRH---GSGSGQSSSYGPYGSG-SGWSSSRGPYESGSGHSS 1988

Query: 278  EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 337
               + ++ +    G G++                      G    +  T  + G   G++
Sbjct: 1989 GLGHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSASGQS 2026

Query: 338  TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRG 395
              S      A +      G+  SG+     +  + +   +  G+G+ G G R  P  GR 
Sbjct: 2027 --SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084

Query: 396  GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGP 455
            G G G S   G+ G   G   G G   +        + ++ ++S              G 
Sbjct: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESS-------SGQSSSYSQHG----------SGS 2127

Query: 456  GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515
            G   G    G   G   RG R G   G     G    G R   G G R G G G   SRG
Sbjct: 2128 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG-RQGSGSGHSPSRG 2186

Query: 516  EH 517
             H
Sbjct: 2187 RH 2188



 Score =  130 bits (326), Expect = 4e-30
 Identities = 143/543 (26%), Positives = 191/543 (35%), Gaps = 94/543 (17%)

Query: 22   GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTPQGY 75
            G G  Q SS  PYG  S SG+S S      G S  S  G       Q++GYG   +  G+
Sbjct: 1485 GSGSGQSSSYSPYG--SGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542

Query: 76   GSTGGYGSSQSSQSSY--------GQQSSY----------PGYGQQPAPSSTS---GSYG 114
             ST G   S S QSS         GQ SS+           GYG+Q + S  S   G  G
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602

Query: 115  SSS-QSSSYGQPQSG-----SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
            S S QS SYG+  SG     S  Q  S  G+   +G  +S +     GQ + Y+    G 
Sbjct: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS-----GQSSSYSQHGSGS 1657

Query: 169  GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228
            G   G G +G      S G   G    +  + G  GS   G +   G GR GSG G    
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS---GSRQSSGHGRQGSGSGQSPS 1714

Query: 229  GGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNT 286
             G +    G     G+ G   GR    G    R G +   G  + GS H S      + +
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774

Query: 287  IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 346
                  G++ +    +  F Q G       TGQ   +                       
Sbjct: 1775 GHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------- 1806

Query: 347  AKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGG 404
                     G+  SG+    S+  + +   +    GR G G G     G+ G G G S  
Sbjct: 1807 ---------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857

Query: 405  GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ-----CKAPKPDGPGGGP 459
             GR G  SG   G G   +  W+    T         +   Q      ++ + +  G   
Sbjct: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917

Query: 460  GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGP-----GKMDSR 514
            G S   G +G   R   G    G   G+       R G G G    +GP     G   SR
Sbjct: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR 1977

Query: 515  GEH 517
            G +
Sbjct: 1978 GPY 1980



 Score =  128 bits (321), Expect = 1e-29
 Identities = 138/533 (25%), Positives = 185/533 (34%), Gaps = 116/533 (21%)

Query: 22   GQGYSQQSSQ-PYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77
            G G  Q SS  PYG  S    S+    SG G SS   + +S   Q++GYG   +  G+ S
Sbjct: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014

Query: 78   TGG-YGSSQSSQSSYGQQSSYPG----YGQQPAPSSTSGSYG----SSSQSSSYGQPQSG 128
            T G +GS+    SS GQ  +  G    +GQ  + SS S  YG     S QS  +GQ  SG
Sbjct: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2074

Query: 129  SYSQQPSYGGQQQSYGQQQS---YNPPQGY-----------GQQNQYNSSSGGGGGGGGG 174
            S  Q PSYG      G+  S   + P  G            GQ + Y+    G G   G 
Sbjct: 2075 S-RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2133

Query: 175  GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234
            G +G      S G   G   G+  + G  GSG    +   G GR GSG G     G +  
Sbjct: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS---RQSSGHGRQGSGSGHSPSRGRHGS 2190

Query: 235  SSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGL 292
             SG     G+ G   GR    G    R G +   G  + GS H S      + +      
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250

Query: 293  GENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAID 352
            G++ +    +  F Q G       TGQ   +                             
Sbjct: 2251 GQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------------- 2276

Query: 353  WFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGF 410
               G+  SG+    S+  + +   +    GR G G G     G+ G G G S   GR G 
Sbjct: 2277 ---GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333

Query: 411  PSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGD 470
             SG   G G   +  W+    T                     G G G   S+       
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYT-------------------QHGSGSGHSSSY------- 2367

Query: 471  DRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRE 523
            ++ G R G                      G+R G   G   S G+H    R+
Sbjct: 2368 EQHGSRSGQS------------------SRGERHGSSSGSSSSYGQHGSGSRQ 2402



 Score =  125 bits (315), Expect = 7e-29
 Identities = 146/560 (26%), Positives = 198/560 (35%), Gaps = 90/560 (16%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDT----SGYGQSSYSSY 58
            S+ Y Q  ++S G        G S  SS  YGQ   SG  QS       SG GQS   S 
Sbjct: 954  SSSYEQHGSRS-GQSSRSEQHGSSSGSSSSYGQHG-SGSRQSLGHGQHGSGSGQSPSPSR 1011

Query: 59   GQ-----SQNTGYGTQSTPQGYGSTGG---YGSSQSS-----QSSYGQQSSYPGYGQQPA 105
            G+      Q++ YG   +  G+ S+ G    GS  SS     +S  GQ S Y  +G    
Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071

Query: 106  PSSTSGSYGSSS-QSSSYGQP-----QSGSYSQQPSYGGQQQSYGQQQSYNPPQ-GYGQQ 158
             SST G +GS+S QSSS GQ      QS S+ Q  S   Q   YG+Q S +    G+GQ+
Sbjct: 1072 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131

Query: 159  NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG------------GGSG 206
               +  S   G  G G           SG G   G+G+ + S G            G S 
Sbjct: 1132 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 1191

Query: 207  GYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265
            GYGQ   R G+   G   G   G   +    G    +  G GR G G      RG     
Sbjct: 1192 GYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 1251

Query: 266  GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325
             G      +H S    S +   +    G +        +    G      + G    +  
Sbjct: 1252 LGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF---GQHESGSGHSSAYSQHGSGSGHFC 1308

Query: 326  TDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGG 385
            +  + G   G+++ +FD   S+      + G   SG+     +    A   +    GR G
Sbjct: 1309 SQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366

Query: 386  RGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443
             G G     G+ G G G S   GR G  SG   G G   +  W+                
Sbjct: 1367 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG------------- 1413

Query: 444  CNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDR 503
            C Q       G G G   S+       ++ G R G                      G+R
Sbjct: 1414 CTQ------HGSGSGHSSSY-------EQHGSRSGQS------------------SRGER 1442

Query: 504  GGFGPGKMDSRGEHRQDRRE 523
             G   G   S G+H    R+
Sbjct: 1443 HGSSSGSSSSYGQHGSGSRQ 1462



 Score =  124 bits (310), Expect = 3e-28
 Identities = 149/530 (28%), Positives = 202/530 (38%), Gaps = 64/530 (12%)

Query: 20   QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGTQSTPQGYGS 77
            Q G G SQ SS  YGQQ S SG S S    G G    SSYGQ    +G+ + S   G GS
Sbjct: 2278 QHGSGSSQSSS--YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335

Query: 78   --TGGYGSSQSSQ----------SSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQ 124
              + G+G  +SS           S  G  SSY  +G +   SS    +GSSS  SSSYGQ
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395

Query: 125  PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184
              SGS   + S G  Q   G  QS +P +G        SSS    G G G  +   +   
Sbjct: 2396 HGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG--WSSSRGPY 2450

Query: 185  SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG-----RGRGGSGGGGGGGGGGYNRSSGGY 239
             SG G   G G+++ S  G S GYGQ           G+ GS  G     G +  SSG  
Sbjct: 2451 ESGSGHSSGLGHRE-SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 2509

Query: 240  EPRGRGG-------GRGGRGGMGGSDRGGFNKFGGPRDQGS--RHDSEQDNSDNNTIFVQ 290
               G+ G       G G +G   G   G   +  G R   S  RH S    S ++     
Sbjct: 2510 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 2569

Query: 291  GLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA 350
            GLGE+        +    G   +  + G    +     + G   G+++       S+ ++
Sbjct: 2570 GLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626

Query: 351  IDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF 410
              +  G+  SG+        + +   +    GR G G G     G +G G      RG +
Sbjct: 2627 SHY--GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 2684

Query: 411  PSGGGGGG--GQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNY 468
             S  G     GQ  +G     +           + C+Q           G  GS  G + 
Sbjct: 2685 ESRLGHSSVFGQHESGSGH--SSAYSQHGSGSGHFCSQ-----------GQHGSTSGQSS 2731

Query: 469  GDDRRGGRGGYDRG-GYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
              D+ G   G     G+RG G  +        G  R G G G+  S G H
Sbjct: 2732 TFDQEGSSTGQSSSYGHRGSGSSQSS------GYGRHGAGSGQSLSHGRH 2775



 Score =  123 bits (309), Expect = 4e-28
 Identities = 153/550 (27%), Positives = 207/550 (37%), Gaps = 92/550 (16%)

Query: 11   TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
            + SYG    Q G G S QSS    Q S SG+S S    G      SS+GQ    G GT  
Sbjct: 749  SSSYG----QHGSG-SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH---GSGTSC 800

Query: 71   TPQ------GYGSTGGYGSSQS-SQSSYGQQSSYPGY-------GQQPAPSSTSGSYGSS 116
            +        G G   G+G  +S S   Y Q  S  G+       G     SS+SG + SS
Sbjct: 801  SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS 860

Query: 117  S-QSSSYGQPQSGSY------------SQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163
            S QSSSYGQ +S S+             Q P +G +    GQ  SY     +G  +  +S
Sbjct: 861  SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR---HGSGSGRSS 917

Query: 164  SSGGGGGGGG-GGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218
            SSG  G G G    +G   SS  S G    GSG G+ +  +  G  SG   + ++ G   
Sbjct: 918  SSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSS 977

Query: 219  GGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFGGPRDQGS 273
            G S   G  G G  +R S G+   G G G+      GR G G      +    GP   GS
Sbjct: 978  GSSSSYGQHGSG--SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY----GPYRSGS 1031

Query: 274  RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333
               S +   ++ +    GLG   +    +  + Q G    +  T           + G  
Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST---------HGQHGST 1082

Query: 334  KGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMG 393
             G+++       S+  +     G+  SG+             ++  G GR G G G   G
Sbjct: 1083 SGQSSSCGQHGASSGQSSS--HGQHGSGS-------------SQSSGYGRQGSGSGQSPG 1127

Query: 394  RGGYGGGG--SGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPK 451
             G  G G   S   GR G  SG     GQ  +G         E+  F   +E +  ++  
Sbjct: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-------LGESSGFG-HHESSSGQSSS 1179

Query: 452  PDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKM 511
                G G G S   G +G   R G+    RG   G         G  G G R   G G+ 
Sbjct: 1180 YSQHGSGSGHSSGYGQHGS--RSGQSS--RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235

Query: 512  DSRGEHRQDR 521
             S   H   R
Sbjct: 1236 GSGSGHSPSR 1245



 Score =  123 bits (309), Expect = 4e-28
 Identities = 155/557 (27%), Positives = 195/557 (35%), Gaps = 143/557 (25%)

Query: 11   TQSYGAYPTQPGQGYSQQSSQPY----GQQSYSGY--SQSTDTSGYGQSSYSS------- 57
            + SYG Y +  G G+S  S  PY    G  S  G+  S+S  +SGYGQ   SS       
Sbjct: 1961 SSSYGPYGS--GSGWSS-SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017

Query: 58   -----YGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSS 108
                  GQS + G    S+ Q   S G +GS  S  S YG+Q S     PG+GQ+ + S 
Sbjct: 2018 QHGSASGQSSSCGQHGASSGQS-SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076

Query: 109  TSGSYG----SSSQSSSYGQP------------------QSGSYSQQPSYGGQQQSYGQQ 146
             S SYG     S +SSS GQ                   QS SYSQ  S  G    YGQ 
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2136

Query: 147  QSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG 206
             S +     G++  + SSS      G    YGQ      SG     G+G Q    G GSG
Sbjct: 2137 GSRSGQSSRGER--HGSSS------GSSSRYGQH----GSGSRQSSGHGRQ----GSGSG 2180

Query: 207  GYGQQDRGGRGRG-GSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265
                + R G G G  S  G  G G G + S G YE                  R G +  
Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYE-----------------SRSGHSSV 2223

Query: 266  GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325
             G  + GS H S      + +      G++ +    +  F Q G       TGQ   +  
Sbjct: 2224 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH-- 2276

Query: 326  TDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGG 385
                                          G+  SG+    S+  + +   +    GR G
Sbjct: 2277 ------------------------------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306

Query: 386  RGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443
             G G     G+ G G G S   GR G  SG   G G   +  W+    T           
Sbjct: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT----------- 2355

Query: 444  CNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGG 501
                      G G G   S+   G   G   RG R G   G     G    G R   G G
Sbjct: 2356 --------QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407

Query: 502  DRG-GFGPGKMDSRGEH 517
              G G G     SRG H
Sbjct: 2408 QHGSGSGQSPSPSRGRH 2424



 Score =  123 bits (309), Expect = 4e-28
 Identities = 121/403 (30%), Positives = 160/403 (39%), Gaps = 27/403 (6%)

Query: 22   GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77
            G G  Q SS  PYG  S    S+    SG G SS   + +S   Q++GYG   +  G+ S
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484

Query: 78   TGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQPSY 136
            T G   S S     GQ SS   +G     SS+ G +GS SSQSS YG+  SGS  Q P +
Sbjct: 2485 THGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGH 2538

Query: 137  GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196
            G  Q+  G +QS  P  G        SSS G  G G G + G      SSG  S     +
Sbjct: 2539 G--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS---YS 2591

Query: 197  QDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMG 255
            Q  SG G S GYGQ   R G+   G   G   G   +    G    +  G GR G G   
Sbjct: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651

Query: 256  GSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNK 315
               RG      G      +H S    S +   +   LG +        +    G      
Sbjct: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF---GQHESGSGHSSAYS 2708

Query: 316  KTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADF 375
            + G    +  +  + G   G+++ +FD   S+      + G   SG+     +    A  
Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGS 2766

Query: 376  NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGG 418
             +   +GR G G G       YG  GSG G   G+   G G G
Sbjct: 2767 GQSLSHGRHGSGSG---QSSSYGQHGSGSGQSSGYSQHGSGSG 2806



 Score =  122 bits (305), Expect = 1e-27
 Identities = 155/564 (27%), Positives = 194/564 (34%), Gaps = 90/564 (15%)

Query: 10   ATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT 68
            AT    +   Q G G SQ S   YGQQ S SG S S    G      SSYGQ   +G G 
Sbjct: 628  ATSGQSSSHGQHGSGSSQSSR--YGQQGSGSGQSPSRGRHGSDFGHSSSYGQ-HGSGSGW 684

Query: 69   QSTPQGYGSTGGYGSSQSSQSSYGQQSSYP----------GY---GQQPAPSSTSGSYGS 115
             S+   +GS  G  S    +S  GQ S Y           GY   G +   SS S  +GS
Sbjct: 685  SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744

Query: 116  SSQ-SSSYGQPQSGSYSQQPSYGGQQQSYGQQ-------QSYNPPQGYGQQNQYNSSSGG 167
            SS  SSSYGQ  SGS+ Q   +G Q    G          S      +GQ     S S  
Sbjct: 745  SSGLSSSYGQHGSGSH-QSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803

Query: 168  GG----GGGGGGNYGQDQSSMSSG----GGSGGGYGNQDQSGG---------------GG 204
             G    G G    +GQ +S    G    G + G + +Q + G                G 
Sbjct: 804  CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863

Query: 205  SGGYGQQDRG-----GRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGGMGG 256
            S  YGQ +       GRGR GSG G   G G     SG    Y   G G GR    G  G
Sbjct: 864  SSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG 923

Query: 257  SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
            S  G  + FG        H S    S   T    G G + + E            +   +
Sbjct: 924  SGSGQSSGFG--------HKSSSGQSSGYTQHGSGSGHSSSYE------------QHGSR 963

Query: 317  TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
            +GQ         + G   G ++        ++ ++        SG     S     +   
Sbjct: 964  SGQSS----RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1019

Query: 377  RGGGNGRGGRGRGGPMGRGGY--GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCE 434
            +    G    G G    RG Y  G G S G G     SG   G GQ  +           
Sbjct: 1020 QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079

Query: 435  NMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRG-GYRGRGGDRGG 493
                   + C Q  A        G  GS    + G  R+G   G   G G RG G  +  
Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 1139

Query: 494  FRGGRGGGDRGGFGPGKMDSRGEH 517
              G      R G G G+  S G+H
Sbjct: 1140 SYG------RHGSGSGRSSSSGQH 1157



 Score =  121 bits (303), Expect = 2e-27
 Identities = 145/539 (26%), Positives = 193/539 (35%), Gaps = 73/539 (13%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS 61
            S+ Y+Q  + S G + +Q   G +   S  + Q+ S +G S S    G G S  SSYGQ 
Sbjct: 1764 SSAYSQHGSGS-GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSS 120
               G G+  +P    S G +GS     SSYGQ  S  G+      SS+SG +GS S QSS
Sbjct: 1823 ---GSGSGQSP----SRGRHGSGSGHSSSYGQHGSGSGW------SSSSGRHGSGSGQSS 1869

Query: 121  SYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGG 175
             +G  +S S     Y+Q  S  G   SY Q  S +     G+Q+  +S S    G  G G
Sbjct: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSG 1929

Query: 176  N----------YGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGG 225
            +           G  QS   S G  G G G     G  GSG      RG    G     G
Sbjct: 1930 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSG 1989

Query: 226  GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GFNKFGGPRDQGSRHDSEQDNS 282
             G     +  S GY   G   G     G  GS  G      + G    Q S H      S
Sbjct: 1990 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGS 2049

Query: 283  DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 342
              ++    G G   +    +    Q G       +G      Y    +G   G ++ S  
Sbjct: 2050 SQSS----GYGRQGSGSGQSPGHGQRG-------SGSRQSPSYGRHGSG--SGRSSSSGQ 2096

Query: 343  DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402
              P    +  +   +  SG     S++   +      G G+ G  R G   RG   G  S
Sbjct: 2097 HGPGLGESSGFGHHESSSGQ--SSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSS 2153

Query: 403  GGGGRGGFPSGG---GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459
            G   R G    G     G G+Q +G    P                   +    G G G 
Sbjct: 2154 GSSSRYGQHGSGSRQSSGHGRQGSGSGHSP-------------------SRGRHGSGSGH 2194

Query: 460  GGSHMGGNYGDDRRGGRGGYD-RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517
              SH     G  R   RG Y+ R G+    G      G      + G G G   S+G+H
Sbjct: 2195 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253



 Score =  119 bits (298), Expect = 7e-27
 Identities = 145/563 (25%), Positives = 207/563 (36%), Gaps = 71/563 (12%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ---SSYSSYG 59
            S+ YTQ  + S   + +  GQ  S+      G++  S    S   S YGQ    S  S G
Sbjct: 475  SSGYTQHGSGS--GHSSGHGQHGSRSGQSSRGERQGSSAGSS---SSYGQHGSGSRQSLG 529

Query: 60   QSQN-TGYGTQSTP-QGYGSTG----------GYGSSQ-SSQSSYGQQSSY-PGYGQQPA 105
             S++ +G G   +P +G   +G          GYGS + SS+  Y   S +  G G Q +
Sbjct: 530  HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES 589

Query: 106  PSSTSGSYG----SSSQSSSYGQ-----PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYG 156
             S  S  YG    SS  SS++GQ      QS S  Q  +  GQ  S+GQ  S     G  
Sbjct: 590  RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGS-----GSS 644

Query: 157  QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSG-----GGGSGGYGQQ 211
            Q ++Y     G G     G +G D    SS G  G G G    +G      G S G+G +
Sbjct: 645  QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHK 704

Query: 212  DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GFNKFGGP 268
               G+  G S  G G      +  S GY   G   G+  R    GS  G    + + G  
Sbjct: 705  SGSGQSSGYSQHGSG------SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758

Query: 269  RDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT--NKKTGQPMINLYT 326
              Q S H  +   S ++   V+    +    S   +        +  + ++G    + + 
Sbjct: 759  SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFG 818

Query: 327  DRETGKLKG-------EATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGG 379
              E+G  +G           S      + +      G+  S +    S+    +  +   
Sbjct: 819  QHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHAS 878

Query: 380  GNGRGGRGRGGPMGRG--GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437
            G GR G G G   G G  G G G S   GR G  SG     G+  +G       + ++  
Sbjct: 879  GRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG-------SGQSSG 931

Query: 438  FSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
            F  ++   Q       G G G   S+   G   G   R  + G   G     G    G R
Sbjct: 932  FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR 991

Query: 496  GGRGGGDRG-GFGPGKMDSRGEH 517
               G G  G G G     SRG H
Sbjct: 992  QSLGHGQHGSGSGQSPSPSRGRH 1014



 Score =  119 bits (297), Expect = 9e-27
 Identities = 143/518 (27%), Positives = 196/518 (37%), Gaps = 78/518 (15%)

Query: 11   TQSYGAYPTQPGQGYSQQSSQPYGQ-QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ 69
            + S G Y ++ G       S  +GQ +S SG+S +    G G   + S GQ  +T  G  
Sbjct: 1268 SSSRGPYESRSGH------SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-GQS 1320

Query: 70   STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTS---GSYGSSS-QSSSYGQP 125
            ST    GS+ G  SS   + S   QSS  GYG+  A S  S   G +GS S  SSSYGQ 
Sbjct: 1321 STFDQEGSSTGQSSSYGHRGSGSSQSS--GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378

Query: 126  QSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMS 185
             SGS     S G      GQ   +    G+ + + + SS     G G G +   +Q    
Sbjct: 1379 GSGS-GWSSSSGRHGSGSGQSSGF----GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSR 1433

Query: 186  SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
            SG  S    G +  S  G S  YGQ   G R   G G  G G G   + S G +   G G
Sbjct: 1434 SGQSS---RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH---GSG 1487

Query: 246  GGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYF 305
             G+       GS   G++   GP + GS H S   + ++ +    G G++          
Sbjct: 1488 SGQSSSYSPYGSG-SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQH---------- 1536

Query: 306  KQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIK 365
                        G    +  T  + G   G+++                 G+  + +   
Sbjct: 1537 ------------GSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQS 1569

Query: 366  VSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGG--SGGGGRGGFPSGGGGGGGQQRA 423
             S     +  ++  G GR G G G   G G  G G   S   GR G  SG     GQ  +
Sbjct: 1570 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1629

Query: 424  GDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG 483
            G         E+  F   +E +  ++      G G G S   G +G  R G     +R G
Sbjct: 1630 G-------LGESSGFG-HHESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHG 1680

Query: 484  YRGRGGDRGGFRGG----RGGGDRGGFGPGKMDSRGEH 517
               R   R G  G       G  R G G G+  SRG H
Sbjct: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718



 Score =  115 bits (287), Expect = 1e-25
 Identities = 146/574 (25%), Positives = 205/574 (35%), Gaps = 71/574 (12%)

Query: 3   SNDYTQQATQSYGAYPT-QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ 60
           S+ Y +Q + S+ +    Q G G  Q  S  YGQ  S SG S S DT G G    S + Q
Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQ--SPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQ 233

Query: 61  -----SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
                 Q++GY    +  G+ S  G   S+S QSS G++     +      SS+ G +GS
Sbjct: 234 HKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGER-----HRSSSGSSSSYGQHGS 288

Query: 116 SSQSSSYGQPQSGSYSQQ-PSY------GGQQQSYGQQ---QSYNPPQGY-----GQQNQ 160
            S+ S  G  + GS S+Q PS+       G   S+GQ     SY+  +G+     GQ + 
Sbjct: 289 GSRQS-LGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSG 347

Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG-----SGGYGQQDRGG 215
           +     G G   G   +G      SS G  G   G    SG  G     S  YGQ +   
Sbjct: 348 FGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS 407

Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGS-- 273
           R   G G    G G      S G+  RG G G+    G  G+  G  +   GP   GS  
Sbjct: 408 RHSSGRGQHSSGSG-----QSPGHGQRGSGSGQSPSSGQHGTGFGR-SSSSGPYVSGSGY 461

Query: 274 -----RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDR 328
                 H+S  ++S   T    G G +        +  + G     ++ G    +  +  
Sbjct: 462 SSGFGHHESSSEHSSGYTQHGSGSGHS---SGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518

Query: 329 ETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGR 388
           + G    ++         +  +     G+  SG+    S+        R    G    G 
Sbjct: 519 QHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGS 578

Query: 389 GGPMGRG----------GYGGGGSGGG-----GRGGFPSGGGGGGGQQRAGDWKCPNPTC 433
           G   G G          GYG  GS  G     G+ G  SG     GQ  A   +  +   
Sbjct: 579 GHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQ 638

Query: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG--GNYGDDRRGGRGGYDRGGYRGRGGDR 491
                S  +   Q  +     P  G  GS  G   +YG    G       G +    G  
Sbjct: 639 HGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQS 698

Query: 492 GGFRGGRGGGDRGGF---GPGKMDSRGEHRQDRR 522
            GF    G G   G+   G G   S G  +   R
Sbjct: 699 SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSR 732



 Score =  114 bits (286), Expect = 2e-25
 Identities = 136/514 (26%), Positives = 187/514 (36%), Gaps = 93/514 (18%)

Query: 25  YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG-YGTQSTPQGYGSTGGYGS 83
           YS QSS  YG+Q+    S S  +SG GQ    S GQS N G +G+ S       T G GS
Sbjct: 172 YSGQSSS-YGEQN----SDSHQSSGRGQCGSGS-GQSPNYGQHGSGSGQSSSNDTHGSGS 225

Query: 84  SQSS-----QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGG 138
            QSS     +SS GQ S Y  +G     SS  G +GS S  SS G+    S     SY G
Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY-G 284

Query: 139 QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG--------GGGGNYGQDQSSMSSGGGS 190
           Q  S  +Q   +  QG G +   +    G G G        G G +Y   +    SG G 
Sbjct: 285 QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQ 344

Query: 191 GGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250
             G+G Q +SG G S GY +                G G G++ S G +   G   G+  
Sbjct: 345 TSGFG-QHESGSGQSSGYSKH---------------GSGSGHSSSQGQH---GSTSGQAS 385

Query: 251 RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI 310
             G  GS     + + G  +  SRH S +    + +    G G+                
Sbjct: 386 SSGQHGSSSRQSSSY-GQHESASRHSSGRGQHSSGSGQSPGHGQR--------------- 429

Query: 311 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT 370
                 +GQ               G+    F    S+        G   SG+     F  
Sbjct: 430 ---GSGSGQ-----------SPSSGQHGTGFGRSSSS--------GPYVSGSGYSSGFGH 467

Query: 371 RRADFNRGGGNGRGGRGRGGPMGRGGYG--GGGSGGGGRGGFPSGGGGGGGQQRAGDWKC 428
             +      G  + G G G   G G +G   G S  G R G  +G     GQ  +G    
Sbjct: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG---- 523

Query: 429 PNPTCENMNFSWRNECNQCKAPKPD----GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGY 484
              + +++  S R+     ++P P       G     S+    YG  R   RG Y+ G  
Sbjct: 524 ---SRQSLGHS-RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579

Query: 485 RGRGGDRGGFRGGRGGG-DRGGFGPGKMDSRGEH 517
              G      R G+  G  + G   G   + G+H
Sbjct: 580 HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH 613



 Score =  110 bits (274), Expect = 4e-24
 Identities = 141/530 (26%), Positives = 193/530 (36%), Gaps = 76/530 (14%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQS-SYS----SYGQSQNTGYGTQSTPQGYGSTGG 80
           S+QS       S SG+S S    G G S SYS      G  Q +G+G   +  G G + G
Sbjct: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHES--GSGQSSG 360

Query: 81  Y---GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQPQSGSYSQQPSY 136
           Y   GS     SS GQ  S  G       +S+SG +GSSS QSSSYGQ +S S   + S 
Sbjct: 361 YSKHGSGSGHSSSQGQHGSTSGQ------ASSSGQHGSSSRQSSSYGQHESAS---RHSS 411

Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196
           G  Q S G  QS     G+GQ+   +  S   G  G G           SG G   G+G+
Sbjct: 412 GRGQHSSGSGQS----PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGH 467

Query: 197 QDQSGGGGSG----GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRG 252
            + S    SG    G G     G G+ GS  G    G     S+G     G+ G  G R 
Sbjct: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGS-GSRQ 526

Query: 253 GMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVT---IESVADYFKQIG 309
            +G S R G      P     RH+S    S +      G G + +    ES + +   +G
Sbjct: 527 SLGHS-RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG 585

Query: 310 IIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFA 369
                          + +  +G+  G          S+        G+  S +    S  
Sbjct: 586 ---------------HQESRSGQSSGYGQHGSSSGHSST------HGQHGSTSGQSSSCG 624

Query: 370 TRRADFNRGGGNGRGGRG--RGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGD-W 426
              A   +   +G+ G G  +    G+ G G G S   GR G   G     GQ  +G  W
Sbjct: 625 QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGW 684

Query: 427 KCPN-----PTCENMNFSWRNECNQCKAPKPDGPGGGPG------GSHMGGNYGDDRRGG 475
              N      + ++  F  ++   Q       G G          GS  G +   ++ G 
Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744

Query: 476 RGGYDRG-GYRGRGGDRGGFRGGRGGGD-------RGGFGPGKMDSRGEH 517
             G     G  G G  +    G +G G        R G   G   S G+H
Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794



 Score =  110 bits (274), Expect = 4e-24
 Identities = 141/556 (25%), Positives = 191/556 (34%), Gaps = 86/556 (15%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQ------STDTSGYGQ----SSYSSYGQSQNTGYGTQST 71
           G G+S    Q     SYS YS+      S  TSG+GQ    S  SS      +G G  S+
Sbjct: 315 GSGHSSSHGQHGSGSSYS-YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373

Query: 72  PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS----SSQSSSYGQPQS 127
              +GST G  SS     S  +QSS   YGQ  + S  S   G     S QS  +GQ  S
Sbjct: 374 QGQHGSTSGQASSSGQHGSSSRQSS--SYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431

Query: 128 GSYSQQPSYGGQQQSYGQQQSYNP-------PQGYGQQNQYNSSSGG------GGGGGGG 174
           GS  Q PS G     +G+  S  P         G+G     +  S G      G G   G
Sbjct: 432 GS-GQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSG 490

Query: 175 GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234
                 +S  SS G   G       S  G S  YGQ   G R   G    G G G   + 
Sbjct: 491 HGQHGSRSGQSSRGERQG-------SSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543

Query: 235 SSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGE 294
           S G +E   R     G  G G     G +   GP + GS H S   + ++ +    G G+
Sbjct: 544 SRGRHESGSRQSSSYGPHGYG----SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ 599

Query: 295 NVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWF 354
                    +    G   T+ + G       +  + G   G+++        +  +  + 
Sbjct: 600 ---------HGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY- 649

Query: 355 DGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYG---------GGGSGGG 405
            G++ SG+    S     +DF      G+ G G G     G +G         G  SG G
Sbjct: 650 -GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSG 708

Query: 406 GRGGFPSGGGG---GGGQQRAGDWKCPNPTCENMNFS--WRNECNQCKAPKPDGPGGGPG 460
              G+   G G     G ++ G     +   E    S    +   Q  +      G G  
Sbjct: 709 QSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768

Query: 461 GSHMGGNYGDDRRGGRGGYDR---------------GGYRGRGGDRGGFRGGRGGGDRG- 504
           GS  G +    R G   G+                 G Y    G   GF     G  +G 
Sbjct: 769 GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGY 828

Query: 505 ---GFGPGKMDSRGEH 517
              G   G   S+G H
Sbjct: 829 SQHGSASGHFSSQGRH 844



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 95/307 (30%), Positives = 127/307 (41%), Gaps = 48/307 (15%)

Query: 3    SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQST--------DTSGYGQ- 52
            S+ Y +Q + S G  P    +G   + S  YG+  S SG S S+        ++SG+G  
Sbjct: 2522 SSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580

Query: 53   -------SSYSSYGQSQ--NTGYGTQSTPQGYGSTGG-YGSSQSSQSSYGQQSS----YP 98
                   SSYS +G     ++GYG   +  G  S G  +GSS  S S YGQ  S      
Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640

Query: 99   GYGQQPAPSSTS---GSYGSS-SQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQ- 153
            G+G+Q + S  S   G +GS    SSS+GQ  SGS  +  S G  +   G    +   + 
Sbjct: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRLGHSSVFGQHES 2699

Query: 154  GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-----GY 208
            G G  + Y+    G G     G +G      S+    G   G     G  GSG     GY
Sbjct: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 2759

Query: 209  GQQDRGG-----RGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGGMGGSDRG 260
            G+   G       GR GSG G     G +   SG   GY   G G G+ G        +G
Sbjct: 2760 GRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYC----KG 2815

Query: 261  GFNKFGG 267
            G N  GG
Sbjct: 2816 GSNHDGG 2822



 Score = 92.4 bits (228), Expect = 9e-19
 Identities = 124/483 (25%), Positives = 170/483 (35%), Gaps = 69/483 (14%)

Query: 54  SYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY-GQQSSYPGYGQQPAPSSTSGS 112
           S+SS+   +N  Y           T       S Q  + GQ +SY G       SS+ G 
Sbjct: 128 SHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQ------SSSYGE 181

Query: 113 YGSSS-QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG 171
             S S QSS  GQ  SGS        GQ  +YGQ  S     G GQ     SSS    G 
Sbjct: 182 QNSDSHQSSGRGQCGSGS--------GQSPNYGQHGS-----GSGQ-----SSSNDTHGS 223

Query: 172 GGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQ-------DRGGRGRGGSGGG 224
           G G + G  Q   SSG  SG    +Q  SG G S GYGQ         RG R R  SG  
Sbjct: 224 GSGQSSGFSQHKSSSGQSSGY---SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSS 280

Query: 225 GG-GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283
              G  G  +R S G+  +G G  +       GS   G +   G    GS +   + + +
Sbjct: 281 SSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG-SGHSSSHGQHGSGSSYSYSRGHYE 339

Query: 284 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 343
           + +    G G++ +    +  +          K G    +  +  + G   G+A+ S   
Sbjct: 340 SGSGQTSGFGQHESGSGQSSGY---------SKHGSGSGHSSSQGQHGSTSGQASSSGQH 390

Query: 344 PPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSG 403
             S++ +  +  G+  S +          +   +  G+G+ G G G     G +G G   
Sbjct: 391 GSSSRQSSSY--GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGR 448

Query: 404 GGGRGGFPSGGG--GGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGG 461
               G + SG G   G G   +                  +E +        G G   G 
Sbjct: 449 SSSSGPYVSGSGYSSGFGHHESS-----------------SEHSSGYTQHGSGSGHSSGH 491

Query: 462 SHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG-GFGPGKMDSRGEHRQD 520
              G   G   RG R G   G     G    G R   G    G G G     SRG H   
Sbjct: 492 GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESG 551

Query: 521 RRE 523
            R+
Sbjct: 552 SRQ 554



 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 86/267 (32%), Positives = 107/267 (40%), Gaps = 38/267 (14%)

Query: 11   TQSYGAYPTQPGQG--YSQQSS-----QPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS- 61
            +  +G + +  GQ   YSQ  S       YGQ  S SG S   +  G    S S YGQ  
Sbjct: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG 2633

Query: 62   ----QNTGYGTQSTPQGYG-STGGYGSSQSSQSSYGQQSSYPGYGQQPAP-------SST 109
                Q++G+G Q +  G   S G +GS     SS+GQ  S  G      P       SS 
Sbjct: 2634 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSV 2693

Query: 110  SGSYGSSS-QSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQ-QSYNPPQGYGQQNQYN 162
             G + S S  SS+Y Q  SGS       Q  S  GQ  ++ Q+  S      YG +   +
Sbjct: 2694 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS 2753

Query: 163  SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ------QDRGGR 216
            S S G G  G G           SG G    YG Q  SG G S GY Q      QD    
Sbjct: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYG-QHGSGSGQSSGYSQHGSGSGQDGYSY 2812

Query: 217  GRGGSGGGGGGGGG---GYNRSSGGYE 240
             +GGS   GG  G     +  S+  YE
Sbjct: 2813 CKGGSNHDGGSSGSYFLSFPSSTSPYE 2839



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 47/140 (33%), Positives = 56/140 (40%), Gaps = 14/140 (10%)

Query: 19   TQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTP 72
            +Q G G     SQ  GQ  S SG S + D  G      SSYG      SQ++GYG     
Sbjct: 2708 SQHGSGSGHFCSQ--GQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 2765

Query: 73   QGYG-STGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS 127
             G   S G +GS     SSYGQ  S      GY Q  + S   G Y      S++    S
Sbjct: 2766 SGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG-YSYCKGGSNHDGGSS 2824

Query: 128  GSYSQQPSYGGQQQSYGQQQ 147
            GSY            Y Q+Q
Sbjct: 2825 GSYFLSFPSSTSPYEYVQEQ 2844


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  101 bits (252), Expect = 1e-21
 Identities = 74/197 (37%), Positives = 87/197 (44%), Gaps = 39/197 (19%)

Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ 160
           GQ+   SS +G  G   +  S      GSY +  S GG   SYG                
Sbjct: 461 GQEDFESSGAGKIGLGGRGGS-----GGSYGRG-SRGGSGGSYG---------------- 498

Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGG 220
                GGG GGG GG  G       S GGSGG YG    SGGG  GGYG    GG   G 
Sbjct: 499 -----GGGSGGGYGGGSG-------SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGS 546

Query: 221 SGGGGGGGGGGY--NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSE 278
            GG  GG GG Y     SGG    G GGG G RGG GGS  GG + FGG  + G  +   
Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS-HGGGSGFGG--ESGGSYGGG 603

Query: 279 QDNSDNNTIFVQGLGEN 295
           ++ S +   +  G G++
Sbjct: 604 EEASGSGGGYGGGSGKS 620



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 57/124 (45%), Positives = 63/124 (50%), Gaps = 14/124 (11%)

Query: 156 GQQNQYNSSSGG----GGGGGGGGNYGQDQSSMSSG----GGSGGGYGNQDQSGGGGSGG 207
           G Q  + SS  G    GG GG GG+YG+     S G    GGSGGGYG    S GG  G 
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519

Query: 208 YGQQDRGGRGRGGSGGGG--GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265
           YG    GG G GG  GGG  GG GGG++  SGG    G GG  GG  G GG   GG+   
Sbjct: 520 YG----GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG 575

Query: 266 GGPR 269
            G R
Sbjct: 576 SGSR 579



 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 72/176 (40%), Positives = 76/176 (43%), Gaps = 31/176 (17%)

Query: 74  GYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133
           G G  GG G S    S  G   SY G G        SGS G S    SYG    GS S  
Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSG--GSYG---GGSGSGG 528

Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193
            S GG               G G    ++  SGGG  GG GGNYG       SGGGSGGG
Sbjct: 529 GSGGGY--------------GGGSGGGHSGGSGGGHSGGSGGNYG---GGSGSGGGSGGG 571

Query: 194 YGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG 249
           YG    S GG  G +G    GG G GG  GG  GGG   + S GGY     GGG G
Sbjct: 572 YGGGSGSRGGSGGSHG----GGSGFGGESGGSYGGGEEASGSGGGY-----GGGSG 618



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 57/133 (42%), Positives = 62/133 (46%), Gaps = 25/133 (18%)

Query: 159 NQYNSSSGGGGGG--GGGGNYGQDQSSMSSGGGSGG--------GYGNQDQS-------- 200
           + Y S SGGGGGG  G GG+     S  SS GG GG        GYG             
Sbjct: 8   SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67

Query: 201 ------GGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM 254
                 GGG  GG+     GG   GGS G GG  GGGY+ SSGG+     GG  GG GG 
Sbjct: 68  SFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYS-SSGGFGGGFGGGSGGGFGGG 126

Query: 255 GGSDRGGFNKFGG 267
            GS  GGF  FGG
Sbjct: 127 YGSGFGGFGGFGG 139



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 67/159 (42%), Positives = 75/159 (47%), Gaps = 27/159 (16%)

Query: 74  GYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133
           G G  GG GS  S +SSY + SS  G G     SS+SG  G SS+    G   S  YS  
Sbjct: 15  GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS-- 72

Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGG-GGGGGGNYGQDQSSMSSGGGSGG 192
             YGG                 G    +++SS GGG GGG  G  G      SS GG GG
Sbjct: 73  --YGG-----------------GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGG 113

Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231
           G+G    SGGG  GGYG    G  G GG GGG GGG GG
Sbjct: 114 GFGG--GSGGGFGGGYGS---GFGGFGGFGGGAGGGDGG 147



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 60/149 (40%), Positives = 69/149 (46%), Gaps = 17/149 (11%)

Query: 119 SSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG------G 172
           SSSY     G        GG  +S      ++   G G   +++SSSG GGG       G
Sbjct: 7   SSSYLSRSGGGGGGGLGSGGSIRS--SYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64

Query: 173 GGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGY 232
           GGG++G      S GGGSGGG+      GG G G  G     G G   SGG GGG GGG 
Sbjct: 65  GGGSFGY-----SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG- 118

Query: 233 NRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
              SGG    G G G GG GG GG   GG
Sbjct: 119 ---SGGGFGGGYGSGFGGFGGFGGGAGGG 144



 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 55/136 (40%), Positives = 63/136 (46%), Gaps = 19/136 (13%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG--FPSGGGGGGGQQRAGDWKCPNPTC 433
           +R GG G GG G GG + R  Y    S GGG GG  F S  G GGG  R     C     
Sbjct: 12  SRSGGGGGGGLGSGGSI-RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV----CGRGGG 66

Query: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493
            +  +S+             G GGG   S +GG +G   RG  GG   GGY   GG  GG
Sbjct: 67  GSFGYSYGG-----------GSGGGFSASSLGGGFGGGSRGF-GGASGGGYSSSGGFGGG 114

Query: 494 FRGGRGGGDRGGFGPG 509
           F GG GGG  GG+G G
Sbjct: 115 FGGGSGGGFGGGYGSG 130



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 55/132 (41%), Positives = 57/132 (43%), Gaps = 17/132 (12%)

Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
           RGG  G  GRG  G  G G YGGGGSGGG  GG  S GG GG                  
Sbjct: 478 RGGSGGSYGRGSRGGSG-GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG----------- 525

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRG-GRGGYDRGGYRGRGGDRGGFR 495
             S              G  GG GG H GG+ G+   G G GG   GGY G  G RGG  
Sbjct: 526 --SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSG 583

Query: 496 GGRGGGDRGGFG 507
           G  GGG   GFG
Sbjct: 584 GSHGGG--SGFG 593



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 53/135 (39%), Positives = 59/135 (43%), Gaps = 20/135 (14%)

Query: 378 GGGNGRG-GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
           GGG+G G G G G   G GG  GGGSG GG  G   GGG GGG            +  N 
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNY 558

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
                            G GGG GG + GG+     RGG GG   GG  G GG+ GG  G
Sbjct: 559 GGG-------------SGSGGGSGGGYGGGS---GSRGGSGG-SHGGGSGFGGESGGSYG 601

Query: 497 G--RGGGDRGGFGPG 509
           G     G  GG+G G
Sbjct: 602 GGEEASGSGGGYGGG 616



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 61/174 (35%), Positives = 72/174 (41%), Gaps = 21/174 (12%)

Query: 51  GQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTS 110
           GQ  + S G  +  G G +    G G + G GS   S  SYG   S  GYG      S  
Sbjct: 461 GQEDFESSGAGK-IGLGGRG---GSGGSYGRGSRGGSGGSYGGGGSGGGYGG--GSGSRG 514

Query: 111 GSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG 170
           GS GS    S  G    G Y    S GG     G   S      YG  +     SGGG G
Sbjct: 515 GSGGSYGGGSGSGGGSGGGYGGG-SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573

Query: 171 GGG------GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218
           GG       GG++G        GG SGG YG  +++ G G GGYG    GG G+
Sbjct: 574 GGSGSRGGSGGSHG---GGSGFGGESGGSYGGGEEASGSG-GGYG----GGSGK 619



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 53/160 (33%), Positives = 59/160 (36%), Gaps = 51/160 (31%)

Query: 360 SGNPIKVSFATRRADFNRGGGNGRGGR---------------GRGGPMGRGGYGGGGSGG 404
           SG  I+ S++     F+  GG G GGR               GRGG  G  GY  GG  G
Sbjct: 24  SGGSIRSSYSR----FSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG-GSFGYSYGGGSG 78

Query: 405 GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHM 464
           GG      GGG GGG +  G                               G   GG   
Sbjct: 79  GGFSASSLGGGFGGGSRGFG-------------------------------GASGGGYSS 107

Query: 465 GGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG 504
            G +G    GG GG   GGY    G  GGF GG GGGD G
Sbjct: 108 SGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGG 147



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 58/185 (31%), Positives = 68/185 (36%), Gaps = 41/185 (22%)

Query: 22  GQGYSQQSSQPYGQQSYSG----YSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGS 77
           G G    S   YG+ S  G    Y       GYG  S S  G   + G G+ S   G GS
Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS---GGGS 530

Query: 78  TGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137
            GGYG       S G    + G         + G+YG  S S                 G
Sbjct: 531 GGGYGGGSGGGHSGGSGGGHSG--------GSGGNYGGGSGSG----------------G 566

Query: 138 GQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG--GGNYGQDQSSMSSGGGSGGGYG 195
           G    YG         G G +     S GGG G GG  GG+YG  + +  SGGG GGG G
Sbjct: 567 GSGGGYG--------GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618

Query: 196 NQDQS 200
               S
Sbjct: 619 KSSHS 623



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 48/131 (36%), Positives = 50/131 (38%), Gaps = 44/131 (33%)

Query: 385 GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNEC 444
           G G+ G  GRGG  GG  G G RGG  SGG  GGG                         
Sbjct: 469 GAGKIGLGGRGG-SGGSYGRGSRGG--SGGSYGGG------------------------- 500

Query: 445 NQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG 504
                    G GGG GG       G   RGG GG   GG    GG  GG+ GG GGG  G
Sbjct: 501 ---------GSGGGYGG-------GSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544

Query: 505 GFGPGKMDSRG 515
           G G G     G
Sbjct: 545 GSGGGHSGGSG 555



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 46/164 (28%), Positives = 65/164 (39%), Gaps = 16/164 (9%)

Query: 27  QQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQS 86
           +Q S  Y  +S  G      + G  +SSYS +  S   G G +     + S+ GYG   S
Sbjct: 4   RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGR-----FSSSSGYGGGSS 58

Query: 87  SQSSYGQQSSYP-----GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQ 141
                G   S+      G G   + SS  G +G  S+   +G    G YS    +GG   
Sbjct: 59  RVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRG--FGGASGGGYSSSGGFGG--- 113

Query: 142 SYGQQQSYNPPQGYGQQ-NQYNSSSGGGGGGGGGGNYGQDQSSM 184
            +G         GYG     +    GG GGG GG     ++S+M
Sbjct: 114 GFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTM 157



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 27/53 (50%), Positives = 31/53 (58%), Gaps = 5/53 (9%)

Query: 376 NRGGGNGRGGRGRGGPMG----RGGYGGGGSGGGGRGGFPSGGGGGGGQQRAG 424
           N GGG+G GG   GG  G    RGG GG   GG G GG  SGG  GGG++ +G
Sbjct: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG-ESGGSYGGGEEASG 608



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 13  SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST- 71
           SYG      G G    S   YG  S  G+S  +   G+   S  +YG    +G G+    
Sbjct: 519 SYGG-----GSGSGGGSGGGYGGGSGGGHSGGSG-GGHSGGSGGNYGGGSGSGGGSGGGY 572

Query: 72  PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY 122
             G GS GG G S    S +G +S    YG     S + G YG  S  SS+
Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESG-GSYGGGEEASGSGGGYGGGSGKSSH 622



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 2/48 (4%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGG--GGSGGGGRGGFPSGGGGGGGQQRA 423
           GGG+G  G   G   G  G+GG  GGS GGG     SGGG GGG  ++
Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 9/65 (13%)

Query: 218 RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR----GGMGGSD-----RGGFNKFGGP 268
           R G GGGGG G GG  RSS        GGG GGR     G GG       RGG   FG  
Sbjct: 13  RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72

Query: 269 RDQGS 273
              GS
Sbjct: 73  YGGGS 77



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 14/72 (19%)

Query: 445 NQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGG-YDRGGYRGRGGDRGGFRGGRGGGDR 503
           N  +  + D    G G   +GG      RGG GG Y RG   G GG  GG      GG  
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGG------RGGSGGSYGRGSRGGSGGSYGG------GGSG 503

Query: 504 GGFGPGKMDSRG 515
           GG+G G   SRG
Sbjct: 504 GGYGGGS-GSRG 514



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 47/183 (25%), Positives = 58/183 (31%), Gaps = 67/183 (36%)

Query: 13  SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72
           SY  + +  G G   + S   G   Y G S      G G S   SYG     G+   S  
Sbjct: 31  SYSRFSSSGGGGGGGRFSSSSG---YGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLG 87

Query: 73  QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
            G+G  GG                             S  +G +S          G YS 
Sbjct: 88  GGFG--GG-----------------------------SRGFGGAS---------GGGYSS 107

Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
              +GG               G+G        SGGG GGG G  +G        GGG+GG
Sbjct: 108 SGGFGG---------------GFG------GGSGGGFGGGYGSGFG---GFGGFGGGAGG 143

Query: 193 GYG 195
           G G
Sbjct: 144 GDG 146



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 28/85 (32%), Positives = 30/85 (35%), Gaps = 18/85 (21%)

Query: 444 CNQCKAPKPDGPGGGPGG---------------SHMGGNYGDDRRGGRGGYDRGGYR--G 486
           C Q  +      GGG GG               S  GG  G  R     GY  G  R  G
Sbjct: 3   CRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCG 62

Query: 487 RGGDRGGFRGGRGGGDRGGFGPGKM 511
           RGG  G F    GGG  GGF    +
Sbjct: 63  RGGG-GSFGYSYGGGSGGGFSASSL 86



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 8/42 (19%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGG 417
           + GGG+G GG         G YGGG    G  GG+  GGG G
Sbjct: 585 SHGGGSGFGGE------SGGSYGGGEEASGSGGGY--GGGSG 618


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score =  101 bits (251), Expect = 2e-21
 Identities = 89/272 (32%), Positives = 121/272 (44%), Gaps = 41/272 (15%)

Query: 268 PRDQGSRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325
           P+   SR DS +  +      IFV G+ E+    ++ DYF++ G I+T        I + 
Sbjct: 107 PKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIET--------IEVM 158

Query: 326 TDRETGKLKGEATVSFDDPPSA-KAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGN-GR 383
            DR++GK +G A V+FDD  +  K  +  +     +G+  +V  A  + +    G   GR
Sbjct: 159 EDRQSGKKRGFAFVTFDDHDTVDKIVVQKYH--TINGHNCEVKKALSKQEMQSAGSQRGR 216

Query: 384 GGRGRGGPMGRGGYGGGGSGG-------GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
           GG G G  MGRGG  GGG G        GGRGG+  GGGG  G    GD        +  
Sbjct: 217 GG-GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGG 275

Query: 437 NFSWRNECNQCKAPKPDGP-----------GGGPGGSHMGGNYGDDRRGGRGGY-DRGGY 484
           N+      +        GP           GGG  G + GGN+G    GG G Y D G Y
Sbjct: 276 NYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNY 335

Query: 485 RGR-----GGDRGGFRGGRGGGD--RGGFGPG 509
            G+     G  +GG  GGR  G    GG+G G
Sbjct: 336 SGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSG 367



 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 58/154 (37%), Positives = 71/154 (46%), Gaps = 20/154 (12%)

Query: 135 SYGGQQQSYGQQQSYNPPQGYG-----QQNQYNSSSGGGGG-GGGGGNYGQDQSSMSSGG 188
           ++GG   ++G+  ++    GYG      +  Y    GG  G GG GGNYG      S GG
Sbjct: 229 NFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGG 288

Query: 189 GSGGGYGNQDQSGG-GGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN-------RSSGGYE 240
             GGG G  +Q GG GG GGY   + G    G  GGG  GGGG YN       +    Y 
Sbjct: 289 YGGGGPGYGNQGGGYGGGGGYDGYNEG----GNFGGGNYGGGGNYNDFGNYSGQQQSNYG 344

Query: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR 274
           P  +GG  GGR   G    GG+   GG    GSR
Sbjct: 345 PM-KGGSFGGRSS-GSPYGGGYGSGGGSGGYGSR 376



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 53/138 (38%), Positives = 61/138 (44%), Gaps = 12/138 (8%)

Query: 153 QGYGQQNQYNSSSG-----GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207
           Q  G Q      SG     GG  GGGGGN+G+  +    GG  GGG G++   GGG  G 
Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGY 267

Query: 208 YGQQDRGGRGRGGSG----GGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFN 263
            G    GG   GG G    GG GGGG GY    GGY   G GGG  G    G    G + 
Sbjct: 268 NGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGY---GGGGGYDGYNEGGNFGGGNYG 324

Query: 264 KFGGPRDQGSRHDSEQDN 281
             G   D G+    +Q N
Sbjct: 325 GGGNYNDFGNYSGQQQSN 342



 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 50/120 (41%), Positives = 60/120 (50%), Gaps = 12/120 (10%)

Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG--GSGGGYGNQDQSGGGGSGGYGQQDRG 214
           +Q   ++ S  G GGG G   G+  +    GG  G GG +G +   GGGG G  G    G
Sbjct: 204 KQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGG 263

Query: 215 GRGRGGSGGGGG--GGGGGYNRSSGGYEPRG-----RGGGRGGRGGMGGSDRGGFNKFGG 267
             G  G GG GG  GGG GY+ S GGY   G     +GGG GG GG  G + GG   FGG
Sbjct: 264 DGGYNGFGGDGGNYGGGPGYS-SRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGG--NFGG 320



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 58/188 (30%), Positives = 77/188 (40%), Gaps = 29/188 (15%)

Query: 57  SYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSS 116
           S G  +  G G+ +     G+ GG G +     ++G +  Y G G       + GSYG  
Sbjct: 209 SAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGG-----GGSRGSYGGG 263

Query: 117 SQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN 176
                      G Y+    +GG   +YG    Y+   GYG       + GGG GGGGG +
Sbjct: 264 D----------GGYN---GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYD 310

Query: 177 YGQDQSSMSSGGGSGGG--------YGNQDQSGGGG--SGGYGQQDRGGRGRGGSGGGGG 226
            G ++     GG  GGG        Y  Q QS  G    G +G +  G    GG G GGG
Sbjct: 311 -GYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGG 369

Query: 227 GGGGGYNR 234
            GG G  R
Sbjct: 370 SGGYGSRR 377



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 65/185 (35%), Positives = 79/185 (42%), Gaps = 45/185 (24%)

Query: 49  GYGQSSYSSYGQSQNTGYGTQSTPQG--YGSTGGY-GSSQSSQSSY-GQQSSYPGYGQQP 104
           G G  S +  G+  N G G  +  +G  +G  GGY G    S+ SY G    Y G+G   
Sbjct: 215 GRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFG--- 271

Query: 105 APSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSS 164
                 G+YG     SS G    G     P YG Q   YG    Y+   GY +   +   
Sbjct: 272 ---GDGGNYGGGPGYSSRGGYGGGG----PGYGNQGGGYGGGGGYD---GYNEGGNF--- 318

Query: 165 SGGGGGGGGGGNY-------GQDQSS-----------MSSGGGSGGGYGNQDQSGGGGSG 206
             GGG  GGGGNY       GQ QS+            SSG   GGGYG+     GGGSG
Sbjct: 319 --GGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGS-----GGGSG 371

Query: 207 GYGQQ 211
           GYG +
Sbjct: 372 GYGSR 376



 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 44/92 (47%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGG--GGYNRSS 236
           Q+  S  S  G GGG GN    GG   GG G   RGG   G  G GGGGGG  G Y    
Sbjct: 205 QEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGD 264

Query: 237 GGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGP 268
           GGY   G  GG  G GG G S RGG+   GGP
Sbjct: 265 GGYNGFGGDGGNYG-GGPGYSSRGGYGG-GGP 294



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 49/170 (28%), Positives = 67/170 (39%), Gaps = 41/170 (24%)

Query: 13  SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDT--SGYGQSSYSSYGQSQNTGYGTQS 70
           ++G      G G   + S   G   Y+G+         G G SS   YG     GYG Q 
Sbjct: 242 NFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGG-GPGYGNQG 300

Query: 71  TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSY 130
              GYG  GGY         Y +  ++ G           G+YG             G+Y
Sbjct: 301 G--GYGGGGGY-------DGYNEGGNFGG-----------GNYGG-----------GGNY 329

Query: 131 SQQPSYGGQQQSYGQQQSYNPPQG--YGQQNQYNSSSGGGGGGGGGGNYG 178
           +   +Y GQQQS     +Y P +G  +G ++  +   GG G GGG G YG
Sbjct: 330 NDFGNYSGQQQS-----NYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYG 374



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 54/204 (26%), Positives = 70/204 (34%), Gaps = 48/204 (23%)

Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR----GGFNKFGGPRDQ 271
           RGRGG  G   G GG +    G +   G  GGRGG GG GG  R    GG   + G    
Sbjct: 214 RGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGD 273

Query: 272 GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETG 331
           G  +      S        G G                               Y ++  G
Sbjct: 274 GGNYGGGPGYSSRGGYGGGGPG-------------------------------YGNQGGG 302

Query: 332 KLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT----RRADFNRGGGNGRGGRG 387
              G     +++  +       F G  + G      F      +++++    G   GGR 
Sbjct: 303 YGGGGGYDGYNEGGN-------FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRS 355

Query: 388 RGGPMGRGGYG-GGGSGGGGRGGF 410
            G P G GGYG GGGSGG G   F
Sbjct: 356 SGSPYG-GGYGSGGGSGGYGSRRF 378



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/47 (53%), Positives = 29/47 (61%), Gaps = 5/47 (10%)

Query: 475 GRGGYDRGGYRGRGGDRGGFRG--GRGG--GDRGGFGPGKMDSRGEH 517
           GRGG   G + GRGG+ GG  G  GRGG  G RGG+G G   SRG +
Sbjct: 215 GRGG-GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSY 260



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/69 (39%), Positives = 29/69 (42%), Gaps = 28/69 (40%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGS-------------------GG--GGR-------GG 409
           GGG G  G   GG  G G YGGGG+                   GG  GGR       GG
Sbjct: 304 GGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGG 363

Query: 410 FPSGGGGGG 418
           + SGGG GG
Sbjct: 364 YGSGGGSGG 372



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 5/71 (7%)

Query: 24  GYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGS 83
           GY++  +  +G  +Y G     D   Y     S+YG  +   +G +S+   YG  GGYGS
Sbjct: 311 GYNEGGN--FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYG--GGYGS 366

Query: 84  SQSSQSSYGQQ 94
              S   YG +
Sbjct: 367 GGGS-GGYGSR 376


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 15/158 (9%)

Query: 271 QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
           QG R      +  + T+FV+GL E+ T E++ + F            G     + TDRET
Sbjct: 558 QGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD-----------GSVRARIVTDRET 606

Query: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGG-GNGRGGRG-- 387
           G  KG   V F+    AKAA +  +  E  GN + + +A  + +   GG G GRGG G  
Sbjct: 607 GSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGR 666

Query: 388 RGGPMGRGGYGGGGSGG-GGRGGFPSGGGGGGGQQRAG 424
            GG  GRGG+GG G GG GGRGGF  G GGGG  +  G
Sbjct: 667 GGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQG 704



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 62/231 (26%), Positives = 87/231 (37%), Gaps = 25/231 (10%)

Query: 281 NSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVS 340
           + ++ T+ +  L  + T E++ + F++   IK  +             + GK KG A + 
Sbjct: 482 SGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQN------------QNGKSKGYAFIE 529

Query: 341 FDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGG 400
           F     AK A++  + +E  G  I++     R   N      +    +G           
Sbjct: 530 FASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLK 589

Query: 401 GSGGGG--------RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKP 452
            S  G         R    S G G        D K      E+              PK 
Sbjct: 590 ESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKG 649

Query: 453 DGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG--GDRGGFRGGRGGG 501
           +G  GG GG   G       RGGRGG+   G RGRG  G RGGFRGGRGGG
Sbjct: 650 EGGFGGRGGGRGGFGGRGGGRGGRGGF---GGRGRGGFGGRGGFRGGRGGG 697



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 30/54 (55%), Positives = 31/54 (57%), Gaps = 10/54 (18%)

Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPR 269
           +G GG GG GGG GG            GRGGGRGGRGG GG  RGGF   GG R
Sbjct: 648 KGEGGFGGRGGGRGGF----------GGRGGGRGGRGGFGGRGRGGFGGRGGFR 691



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 34/64 (53%), Positives = 38/64 (59%), Gaps = 16/64 (25%)

Query: 192 GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251
           GG+G +    GGG GG+G   RGG GRGG GG GG G GG+          GRGG RGGR
Sbjct: 651 GGFGGR----GGGRGGFG--GRGG-GRGGRGGFGGRGRGGFG---------GRGGFRGGR 694

Query: 252 GGMG 255
           GG G
Sbjct: 695 GGGG 698



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 30/63 (47%), Positives = 32/63 (50%), Gaps = 15/63 (23%)

Query: 167 GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG 226
           GG GG GGG  G         GG GGG G +   GG G GG+G       GRGG  GG G
Sbjct: 651 GGFGGRGGGRGGF--------GGRGGGRGGRGGFGGRGRGGFG-------GRGGFRGGRG 695

Query: 227 GGG 229
           GGG
Sbjct: 696 GGG 698



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGG 231
           G     D +     GG GG  G +   GG G G  G+   GGRGRGG GG GG  GG GG
Sbjct: 637 GNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGG 696

Query: 232 YNRSSGGYEPRGR 244
                G ++P+G+
Sbjct: 697 ----GGDHKPQGK 705



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 27/57 (47%), Positives = 32/57 (56%), Gaps = 12/57 (21%)

Query: 166 GGGGGGGGGGNYGQDQSSMSSGGGSGG--GYGNQDQSGGGGSGGYGQQDRGGRGRGG 220
           G GG GGG G +G        GGG GG  G+G + + G GG GG+    RGGRG GG
Sbjct: 652 GFGGRGGGRGGFG------GRGGGRGGRGGFGGRGRGGFGGRGGF----RGGRGGGG 698


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 59/123 (47%), Positives = 64/123 (52%), Gaps = 11/123 (8%)

Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS-GGGYGNQDQSGGGGSGGYGQQD 212
           GYG  +    SSGGG GGG GG+ G      SSGGGS GGGYG     GG  SGG+G   
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG-----GGSSSGGHGGSS 526

Query: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272
            GG G G SGGGGGG GGG   SSGG      GGG GG    GG         G    +G
Sbjct: 527 SGGYGGGSSGGGGGGYGGG---SSGG--GSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581

Query: 273 SRH 275
            R+
Sbjct: 582 PRY 584



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 62/143 (43%), Positives = 69/143 (48%), Gaps = 20/143 (13%)

Query: 150 NPPQGYGQQNQYNSSSGGGGGGGG--GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207
           N  Q Y    +   SSGGGG GGG  GG YG        GG SGGG      SGGG  GG
Sbjct: 444 NEIQTYRSLLEGEGSSGGGGRGGGSFGGGYG--------GGSSGGG-----SSGGGHGGG 490

Query: 208 YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGY---EPRGRGGGR--GGRGGMGGSDRGGF 262
           +G    GG G G SGGG  GGG G   SSGG+      G GGG   GG GG GG   GG 
Sbjct: 491 HGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG 550

Query: 263 NKFGGPRDQGSRHDSEQDNSDNN 285
           +  GG    GS     + +S  +
Sbjct: 551 SSSGGGYGGGSSSGGHKSSSSGS 573



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 52/132 (39%), Positives = 54/132 (40%), Gaps = 17/132 (12%)

Query: 107 SSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG 166
           SS  G  G  S    YG   SG  S    +GG               G      Y   S 
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGH-------------GGSSGGGYGGGSS 504

Query: 167 GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG 226
           GGG  GGG  YG   SS   GG S GGYG    S GGG GGYG    GG    G G GGG
Sbjct: 505 GGGSSGGG--YGGGSSSGGHGGSSSGGYGG--GSSGGGGGGYGGGSSGGGSSSGGGYGGG 560

Query: 227 GGGGGYNRSSGG 238
              GG+  SS G
Sbjct: 561 SSSGGHKSSSSG 572



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 53/136 (38%), Positives = 58/136 (42%), Gaps = 23/136 (16%)

Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSM-------------SSGGGSGGGYGNQDQSG 201
           Y     Y+SS  GGGGGGGG   G   SS+             SSGG SGG +      G
Sbjct: 5   YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64

Query: 202 G---GGSGGYGQQD-------RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251
           G   G SGGYG          RG  G    GG  GG  GG +   G +     GGG  G 
Sbjct: 65  GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGG 124

Query: 252 GGMGGSDRGGFNKFGG 267
           GG GG   GGF   GG
Sbjct: 125 GGFGGGFGGGFGGDGG 140



 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 55/142 (38%), Positives = 58/142 (40%), Gaps = 36/142 (25%)

Query: 379 GGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF--PSGGGGGGGQQRAGDWKCPNPTCENM 436
           GG GRGG   GG  G G  GGG SGGG  GG    SGGG GGG    G            
Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG------------ 507

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
                              GGG GG    G +G    GG GG   GG  G GG  GG  G
Sbjct: 508 -----------------SSGGGYGGGSSSGGHGGSSSGGYGGGSSGG--GGGGYGGGSSG 548

Query: 497 GRGGGDRGGFGPGKMDSRGEHR 518
           G G    GG+G G   S G H+
Sbjct: 549 G-GSSSGGGYGGG--SSSGGHK 567



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 55/145 (37%), Positives = 57/145 (39%), Gaps = 37/145 (25%)

Query: 377 RGGGN---GRGGRGRGGPMGRGGYGGG--GSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431
           RGGG+   G GG   GG    GG+GGG  GS GGG GG  SGGG  GG    G       
Sbjct: 464 RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG------- 516

Query: 432 TCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDR 491
                                    GG GGS  GG  G    GG GGY  GG  G G   
Sbjct: 517 ----------------------SSSGGHGGSSSGGYGGGSSGGGGGGYG-GGSSGGGSSS 553

Query: 492 GGFRGGRGGGDRGGFGPGKMDSRGE 516
           GG  G  GG   GG       S GE
Sbjct: 554 GG--GYGGGSSSGGHKSSSSGSVGE 576



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 60/188 (31%), Positives = 70/188 (37%), Gaps = 53/188 (28%)

Query: 36  QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQS 95
           Q+Y    +   +SG G     S+G     GYG  S+  G  S GG+G      S  G   
Sbjct: 447 QTYRSLLEGEGSSGGGGRGGGSFGG----GYGGGSSGGG-SSGGGHGGGHGGSSGGGYGG 501

Query: 96  SYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGY 155
              G G      S+ G YG  S S  +G   SG                         GY
Sbjct: 502 GSSGGG------SSGGGYGGGSSSGGHGGSSSG-------------------------GY 530

Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG 215
           G       SSGGGGGG GGG+ G        G  SGGGYG     GG  SGG+     G 
Sbjct: 531 G-----GGSSGGGGGGYGGGSSG-------GGSSSGGGYG-----GGSSSGGHKSSSSGS 573

Query: 216 RGRGGSGG 223
            G   S G
Sbjct: 574 VGESSSKG 581



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 59/166 (35%), Positives = 69/166 (41%), Gaps = 29/166 (17%)

Query: 75  YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQP 134
           Y S+  Y SS+S     G      G       SS+ GS G    S  +     GS+S+  
Sbjct: 5   YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS---GGSFSRGS 61

Query: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGGGSGG 192
           S GG                      +  SSGG GG  G GGG++     S S GG  GG
Sbjct: 62  SGGGC---------------------FGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGG 100

Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGG-GGGGGGGYNRSSG 237
            +G    S GGGS G G    GG G GG GGG GGG GG     SG
Sbjct: 101 SFGGG--SFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSG 144



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 51/155 (32%), Positives = 58/155 (37%), Gaps = 36/155 (23%)

Query: 364 IKVSFATRRADFNRGGGNGRGGRGRGGPM-------GRGGYGGGGSGGGGRGGFPSGGGG 416
           ++ S +   +    GGG G GG G GG +        +G  GGG S GG  GG  S G  
Sbjct: 3   VRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62

Query: 417 GGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPG--GGPGGSHMGGNYGDDRRG 474
           GGG                           C      G G  GG GG    G+YG    G
Sbjct: 63  GGG---------------------------CFGGSSGGYGGLGGFGGGSFRGSYGSSSFG 95

Query: 475 GRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPG 509
           G  G   GG    GG  GG   G GG   GGFG G
Sbjct: 96  GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 359 FSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGG 418
           F G   + S+ +     + GG  G G  G GG  G G +GGGG GGGG GG   GG GG 
Sbjct: 80  FGGGSFRGSYGSSSFGGSYGGSFGGGSFG-GGSFGGGSFGGGGFGGGGFGGGFGGGFGGD 138

Query: 419 GQQRAGDWKCPNPTCENMN 437
           G   +G+ K    T +N+N
Sbjct: 139 GGLLSGNEKV---TMQNLN 154



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 52/161 (32%), Positives = 62/161 (38%), Gaps = 41/161 (25%)

Query: 378 GGGNGRGGRGR-------------GGPMGRGGYGGG----GSGGGGRGGFPSGGGGGGGQ 420
           GGG G GG G              GG    GG+ GG    GS GGG  G  SGG GG G 
Sbjct: 20  GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGG 79

Query: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480
              G ++    +  + +F                 GG  GG   GG        G G + 
Sbjct: 80  FGGGSFR---GSYGSSSFG-------------GSYGGSFGGGSFGGG-----SFGGGSFG 118

Query: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDR 521
            GG+ G GG  GGF GG GG   GG   G      ++  DR
Sbjct: 119 GGGF-GGGGFGGGFGGGFGGD--GGLLSGNEKVTMQNLNDR 156



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 5/108 (4%)

Query: 34  GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQS----SQS 89
           G  S  G S      G+G SS   YG   + G  +     G  S+GG+G S S      S
Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGS 534

Query: 90  SYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137
           S G    Y G G     SS+ G YG  S S  +    SGS  +  S G
Sbjct: 535 SGGGGGGYGG-GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/101 (38%), Positives = 45/101 (44%), Gaps = 15/101 (14%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSS-YGQSQNTGYGTQSTPQGYGSTGG 80
           G G+   S   YG  S  G S      GYG  S S  +G S + GYG        GS+GG
Sbjct: 488 GGGHGGSSGGGYGGGSSGGGSSG---GGYGGGSSSGGHGGSSSGGYGG-------GSSGG 537

Query: 81  YGSSQSSQSSYGQQSSYPGYGQQPA----PSSTSGSYGSSS 117
            G      SS G  SS  GYG   +     SS+SGS G SS
Sbjct: 538 GGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESS 578



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 49/172 (28%), Positives = 57/172 (33%), Gaps = 78/172 (45%)

Query: 33  YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG 92
           +    +SG S S  +SG G      +G S            GYG  GG+G          
Sbjct: 47  FSSGGFSGGSFSRGSSGGG-----CFGGSSG----------GYGGLGGFGG--------- 82

Query: 93  QQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152
                          S  GSYGSSS   SYG    G      S+GG              
Sbjct: 83  --------------GSFRGSYGSSSFGGSYGGSFGGG-----SFGG-------------- 109

Query: 153 QGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG 204
                   +   S GGGG GGGG           GGG GGG+G     G GG
Sbjct: 110 ------GSFGGGSFGGGGFGGGG----------FGGGFGGGFG-----GDGG 140



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/152 (29%), Positives = 57/152 (37%), Gaps = 16/152 (10%)

Query: 41  YSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYG-STGGYGSSQSSQSSYGQQ---SS 96
           YS S    G G       G   +    +     G G S+GG+     S+ S G      S
Sbjct: 11  YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70

Query: 97  YPGYGQQPA--PSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154
             GYG        S  GSYGSSS   SYG    G      S+GG     G         G
Sbjct: 71  SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG---------G 121

Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS 186
           +G    +    GGG GG GG   G ++ +M +
Sbjct: 122 FGGGG-FGGGFGGGFGGDGGLLSGNEKVTMQN 152



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 6/78 (7%)

Query: 14  YGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ 73
           YG   +  G G S       G     G      +SG G SS   YG   ++G G +S+  
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG-GHKSS-- 569

Query: 74  GYGSTGGYGSSQSSQSSY 91
              S+G  G S S    Y
Sbjct: 570 ---SSGSVGESSSKGPRY 584


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 113/361 (31%), Positives = 128/361 (35%), Gaps = 100/361 (27%)

Query: 164 SSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGG 223
           +SGGGGGGGG            SGGG  G +G      GGGSGG       G G G SGG
Sbjct: 19  TSGGGGGGGG------------SGGGGCGFFG------GGGSGG----GSSGSGCGYSGG 56

Query: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283
           GG  GGG    SSGG       GG GG GG GG   G     GG    G           
Sbjct: 57  GGYSGGGCGGGSSGG-------GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGG 109

Query: 284 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 343
            +  F  G G +    S    F   G                     G   G  +  F  
Sbjct: 110 GSGCFSSGGGGSSGGGSGC--FSSGG---------------------GGSSGGGSGCFSS 146

Query: 344 PPSAKAAIDWFDGKEFSGNPIKV-SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402
                       G  FSG  ++  S+    +  + GGG+G    G GG     GY GGGS
Sbjct: 147 -----------GGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG-SVCGYSGGGS 194

Query: 403 GGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462
           G GG      G  GG G       +    +C               AP+P   GG  GG 
Sbjct: 195 GCGG------GSSGGSGSGYVSSQQVTQTSC---------------APQPSYGGGSSGGG 233

Query: 463 HMGGNYGDDRRGGRGGYD--RGGYRGRGGD----------RGGFRGGRGGGDR-GGFGPG 509
             GG+ G    GG GG     GG  G G             GG  GG GGG   GG G G
Sbjct: 234 GSGGS-GCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292

Query: 510 K 510
           K
Sbjct: 293 K 293



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 107/332 (32%), Positives = 121/332 (36%), Gaps = 60/332 (18%)

Query: 102 QQPAPS------STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGY 155
           +QP P        TSG  G    S   G    G +    S GG   S G    Y+   GY
Sbjct: 6   KQPTPQPPVDCVKTSGGGGGGGGSGGGG---CGFFGGGGSGGG---SSGSGCGYSGGGGY 59

Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSM--SSGGGSGGGYGNQDQSGGGGSG----GYG 209
                   SSGGGGGGG GG  G    S+  S GGGS GG      SGGGGSG    G G
Sbjct: 60  SGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGG 119

Query: 210 QQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM--GGSDRGGFNKFGG 267
               GG G   SGGGG  GGG    SSGG    G+       GG+  GGS  GG   F  
Sbjct: 120 GSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSS 179

Query: 268 PRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTD 327
               GS        S        G G   +  S + Y     + +T              
Sbjct: 180 GGGGGSVCGYSGGGS--------GCGGGSSGGSGSGYVSSQQVTQT-------------- 217

Query: 328 RETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG 387
                       S    PS         G   SG      F++     + G G G  G G
Sbjct: 218 ------------SCAPQPSYGGGSSGGGGSGGSG-----CFSSGGGGGSSGCGGGSSGIG 260

Query: 388 RGGPM-GRGGYGGGGSGGGGRGGFPSGGGGGG 418
            G  + G G   GGGS GGG GG   GG G G
Sbjct: 261 SGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 85/272 (31%), Positives = 94/272 (34%), Gaps = 34/272 (12%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG--QSQNTGYGTQSTPQGYGSTGGY-- 81
           S Q  QP  Q        S    G G S     G      +G G+  +  GY   GGY  
Sbjct: 2   SYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG 61

Query: 82  ----GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137
               G S       G      G G     S   GS G  S   S G   SG +S     G
Sbjct: 62  GGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS----G 117

Query: 138 GQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQ 197
           G   S G    ++   G          S GGGG  G     Q    +SSGG SGGG G  
Sbjct: 118 GGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCF 177

Query: 198 DQSGGGGSG-GY--GQQDRGGRGRGGSGGG-------------------GGGGGGGYNRS 235
              GGGGS  GY  G    GG   GGSG G                   GG  GGG +  
Sbjct: 178 SSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237

Query: 236 SGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267
           SG +   G GG  G  GG  G   G     GG
Sbjct: 238 SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269



 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 83/249 (33%), Positives = 88/249 (35%), Gaps = 39/249 (15%)

Query: 51  GQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSST- 109
           G SS S  G S   GY       G    GG G         G    Y G G      S  
Sbjct: 44  GGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGC 103

Query: 110 -SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP-----------QGYGQ 157
            S   G S   SS G   SG  S   S GG   S G    ++             Q YG 
Sbjct: 104 FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGG 163

Query: 158 QNQYNSSSGGGG----GGGGGGNYGQDQSSMSSGGGSGGGYGNQ---------------- 197
            +   SS GG G    GGGGG   G        GGGS GG G+                 
Sbjct: 164 VSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQP 223

Query: 198 ----DQSGGGGSGGYGQ-QDRGGRGRGGSGGGGGGGGGGYNRSSGGYE-PRGRGGGRGGR 251
                 SGGGGSGG G     GG G  G GGG  G G G   S GG     G  GG GG 
Sbjct: 224 SYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG 283

Query: 252 GGMGGSDRG 260
             +GGS  G
Sbjct: 284 SSVGGSGSG 292



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 77/223 (34%), Positives = 86/223 (38%), Gaps = 28/223 (12%)

Query: 34  GQQSYSGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG 92
           G  S  G S    + G G   +SS G  S   G G  S+  G  S GG G   S    + 
Sbjct: 93  GGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFS 152

Query: 93  QQS----SYPGYGQQPAPSSTSGSYGSSSQSSSY-GQPQSGSYSQQPSYGGQQQSYGQQQ 147
            Q+    SY G     +    SG + S     S  G    GS     S GG    Y   Q
Sbjct: 153 GQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQ 212

Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG- 206
                    Q +    SSGGGG GG G          SSGGG GG  G     GGG SG 
Sbjct: 213 QVTQTSCAPQPSYGGGSSGGGGSGGSG--------CFSSGGG-GGSSG----CGGGSSGI 259

Query: 207 GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG 249
           G G    GG    G G  GGGGGG    SS G    G G G+G
Sbjct: 260 GSGCIISGGGSVCGGGSSGGGGGG----SSVG----GSGSGKG 294



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 70/206 (33%), Positives = 81/206 (39%), Gaps = 60/206 (29%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT-GYGTQSTPQGYGSTGG 80
           G G+S Q+ Q    QSY G S S  +SG G   +SS G   +  GY    +  G GS+GG
Sbjct: 148 GGGFSGQAVQC---QSYGGVS-SGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGG 203

Query: 81  YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQ 140
            GS   S     Q S  P    QP                SYG   SG        GG  
Sbjct: 204 SGSGYVSSQQVTQTSCAP----QP----------------SYGGGSSG--------GG-- 233

Query: 141 QSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQS 200
                        G G    ++S  GGG  G GGG+ G     + SGGGS          
Sbjct: 234 -------------GSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS--------VC 272

Query: 201 GGGGSGGYGQQDRGGRGRGGSGGGGG 226
           GGG SGG G    GG   GGSG G G
Sbjct: 273 GGGSSGGGG----GGSSVGGSGSGKG 294



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 55/149 (36%), Positives = 62/149 (41%), Gaps = 20/149 (13%)

Query: 378 GGGNGRGGRGRGGPMGRGGY-GGGGSGGGGRGGFPSGGGG------GGGQQRAGDWKCPN 430
           GGG G GG G GG  G   Y GGGGS GGG G F SGGGG      GGG    G   C  
Sbjct: 72  GGGGGIGGCG-GGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGC-- 128

Query: 431 PTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR--GRG 488
                 +                G GG  G +    +YG    GG  G   G +   G G
Sbjct: 129 -----FSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGG 183

Query: 489 GDRGGFRGGR---GGGDRGGFGPGKMDSR 514
           G   G+ GG    GGG  GG G G + S+
Sbjct: 184 GSVCGYSGGGSGCGGGSSGGSGSGYVSSQ 212



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/174 (32%), Positives = 68/174 (39%), Gaps = 30/174 (17%)

Query: 378 GGGNGRGGRGRGGPMGR-------GGYGGGGSGGGGRGGFPSGGGGG------GGQQRAG 424
           GGG+G    G GG  G+       GG   GGS GGG G F SGGGGG      GG    G
Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197

Query: 425 DWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG- 483
                      ++ S +     C AP+P   GG  GG   GG+      GG G    GG 
Sbjct: 198 GGSSGGSGSGYVS-SQQVTQTSC-APQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGG 255

Query: 484 ---------YRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGE---HRQDRRERP 525
                      G G   GG  G  GGG  G    G    +G    H+  +++ P
Sbjct: 256 SSGIGSGCIISGGGSVCGG--GSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAP 307



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 33/80 (41%), Positives = 33/80 (41%), Gaps = 16/80 (20%)

Query: 446 QCKAPKPDGP--------GGGPGGSHMGGNYGDDRRGGRG--------GYDRGGYRGRGG 489
           Q K P P  P        GGG GG   GG  G    GG G        GY  GG    GG
Sbjct: 4   QKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGG 63

Query: 490 DRGGFRGGRGGGDRGGFGPG 509
             GG  GG GGG  GG G G
Sbjct: 64  CGGGSSGGGGGGGIGGCGGG 83


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 70/177 (39%), Positives = 75/177 (42%), Gaps = 37/177 (20%)

Query: 92  GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151
           G++S   G        S S S+ + S   S G    G  S   SYG    SYG       
Sbjct: 488 GEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGS------ 541

Query: 152 PQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQ 211
                          GGGGGGG G+YG   SS  SGGGS G  G     GGGG G YG  
Sbjct: 542 ---------------GGGGGGGRGSYGSGGSSYGSGGGSYGSGG-----GGGGHGSYGSG 581

Query: 212 DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG-RGGRGGMGGSDRGGFNKFGG 267
              G  RGGSGGGGGG  GG          RG GGG  GG  G  GS  GG    GG
Sbjct: 582 SSSGGYRGGSGGGGGGSSGG----------RGSGGGSSGGSIGGRGSSSGGVKSSGG 628



 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 62/145 (42%), Positives = 73/145 (50%), Gaps = 18/145 (12%)

Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGG 220
           + + SGGG  GGGGG YG   SS  SGGGS G       SGGGG GG G    GG   G 
Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG-------SGGGGGGGRGSYGSGGSSYGS 561

Query: 221 SGG--GGGGGGGGY-----NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGS 273
            GG  G GGGGGG+       SSGGY  RG G G GG G  GG   GG +  G    +GS
Sbjct: 562 GGGSYGSGGGGGGHGSYGSGSSSGGY--RG-GSGGGGGGSSGGRGSGGGSSGGSIGGRGS 618

Query: 274 RHDSEQDNSDNNTI-FVQGLGENVT 297
                + +  ++++ FV      VT
Sbjct: 619 SSGGVKSSGGSSSVKFVSTTYSGVT 643



 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 58/164 (35%), Positives = 75/164 (45%), Gaps = 27/164 (16%)

Query: 70  STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
           S+  GY S GG+ S  +   +Y ++++          SST  S G   + SS G    GS
Sbjct: 6   SSRSGYRSGGGFSSGSAGIINYQRRTT---------SSSTRRSGGGGGRFSSCGGG-GGS 55

Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGG 189
           +       G    +G +   N   G  +    + + GGG G G GG YG        GG 
Sbjct: 56  F-------GAGGGFGSRSLVN--LGGSKSISISVARGGGRGSGFGGGYG-------GGGF 99

Query: 190 SGGGYGNQDQSGGG-GSGGYGQQDRGGRGRGGSGGGGGGGGGGY 232
            GGG+G     GGG G GG+G    GG G GG G GGGG GGGY
Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY 143



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 60/161 (37%), Positives = 66/161 (40%), Gaps = 53/161 (32%)

Query: 364 IKVSFATRRADFNRGG--GNGRGGRGRGGPM---GRGGYGGGGSGGGGRGGFPSGG---G 415
           + VS +T     + GG  G G GG G GG     G G YG GG GGGGRG + SGG   G
Sbjct: 501 VSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYG 560

Query: 416 GGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGG 475
            GGG                                  G GGG GG    G+YG      
Sbjct: 561 SGGGSY--------------------------------GSGGGGGGH---GSYG------ 579

Query: 476 RGGYDRGGYR-GRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515
             G   GGYR G GG  GG  GGRG G  GG   G +  RG
Sbjct: 580 -SGSSSGGYRGGSGGGGGGSSGGRGSG--GGSSGGSIGGRG 617



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 46/106 (43%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG 215
           G   +++S  GGGG  G GG +G    S+ + GGS     +  + GG GSG  G    GG
Sbjct: 41  GGGGRFSSCGGGGGSFGAGGGFGS--RSLVNLGGSKSISISVARGGGRGSGFGGGYGGGG 98

Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
            G GG GGGG GGGG      GG+   G GGG  G GG GG   GG
Sbjct: 99  FGGGGFGGGGFGGGG---IGGGGFGGFGSGGGGFGGGGFGGGGYGG 141



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 45/125 (36%), Positives = 57/125 (45%), Gaps = 14/125 (11%)

Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS--GGGSGGGYGNQDQSGG--GGSGGYGQ 210
           +  ++ Y S  G   G  G  NY +  +S S+   GG GG + +    GG  G  GG+G 
Sbjct: 5   FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64

Query: 211 QDRGGRGRGGS--------GGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGF 262
           +     G   S        GG G G GGGY    GG+   G GGG  G GG+GG   GGF
Sbjct: 65  RSLVNLGGSKSISISVARGGGRGSGFGGGY--GGGGFGGGGFGGGGFGGGGIGGGGFGGF 122

Query: 263 NKFGG 267
              GG
Sbjct: 123 GSGGG 127



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 43/122 (35%), Positives = 44/122 (36%), Gaps = 26/122 (21%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437
           G G G  G G GG  GRG YG GGS  G  GG    GGGGGG    G             
Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG------------- 579

Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGG 497
                             GG  GGS  GG      RG  GG   G   GRG   GG +  
Sbjct: 580 -------------SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSS 626

Query: 498 RG 499
            G
Sbjct: 627 GG 628



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 55/146 (37%), Positives = 56/146 (38%), Gaps = 36/146 (24%)

Query: 76  GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135
           G  GGYGS  SS  S G       YG         GSYGS    SSYG    GSY     
Sbjct: 520 GGGGGYGSGGSSYGSGGGS-----YGSGGGGGGGRGSYGSGG--SSYGSG-GGSYGSGGG 571

Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYG 195
            GG   SYG   S            Y   SGGGGGG  GG             GSGGG  
Sbjct: 572 -GGGHGSYGSGSS---------SGGYRGGSGGGGGGSSGGR------------GSGGG-- 607

Query: 196 NQDQSGGGGSGGYGQQDRGGRGRGGS 221
               S GG  GG G    G +  GGS
Sbjct: 608 ----SSGGSIGGRGSSSGGVKSSGGS 629



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 50/141 (35%), Positives = 62/141 (43%), Gaps = 7/141 (4%)

Query: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431
           R+ +  GGG   G  G      R         GGG G F S GGGGG     G +   + 
Sbjct: 8   RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFG--SR 65

Query: 432 TCENMNFSWRNECNQCKAP-KPDGPGGGPGGSHM-GGNYGDDRRGGRGGYDRGGYRGRGG 489
           +  N+  S     +  +   +  G GGG GG    GG +G    GG GG   GG+ G G 
Sbjct: 66  SLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGG-GGIGGGGFGGFGS 124

Query: 490 DRGGFRGG--RGGGDRGGFGP 508
             GGF GG   GGG  GG+GP
Sbjct: 125 GGGGFGGGGFGGGGYGGGYGP 145



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 30/56 (53%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTC 433
           GGG G GG G GG  G GG GGGG GG G GG   GGGG GG    G +    P C
Sbjct: 96  GGGFGGGGFGGGG-FGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY---GPVC 147



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 46/128 (35%), Positives = 50/128 (39%), Gaps = 7/128 (5%)

Query: 7   TQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGY 66
           T   T S G      G GY    S  YG  S  G   S    G G+ SY S G S  +G 
Sbjct: 507 TSHTTISGGGSRGGGGGGYGSGGSS-YG--SGGGSYGSGGGGGGGRGSYGSGGSSYGSGG 563

Query: 67  GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSS---SQSSSYG 123
           G+  +  G G  G YGS  SS   Y   S   G G      S  GS G S     SSS G
Sbjct: 564 GSYGSGGGGGGHGSYGSG-SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622

Query: 124 QPQSGSYS 131
              SG  S
Sbjct: 623 VKSSGGSS 630



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 29/70 (41%), Positives = 32/70 (45%), Gaps = 8/70 (11%)

Query: 454 GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDR-----GGFRGGRGGGDRGGFGP 508
           G G G GGS  G   G    GG GG  RG Y G GG       G +  G GGG  G +G 
Sbjct: 522 GGGYGSGGSSYGSGGGSYGSGGGGGGGRGSY-GSGGSSYGSGGGSYGSGGGGGGHGSYGS 580

Query: 509 GKMDSRGEHR 518
           G   S G +R
Sbjct: 581 G--SSSGGYR 588



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/115 (34%), Positives = 45/115 (39%), Gaps = 35/115 (30%)

Query: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG------GGGGGYNR 234
           Q S  SG  SGGG+ +      G +G    Q R         GGGG      GGGGG   
Sbjct: 4   QFSSRSGYRSGGGFSS------GSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFG 57

Query: 235 SSGGYEPR---------------GRGGGRG-------GRGGMGGSDRGGFNKFGG 267
           + GG+  R                RGGGRG       G GG GG   GG   FGG
Sbjct: 58  AGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG-GGFGG 111



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 43/151 (28%), Positives = 47/151 (31%), Gaps = 45/151 (29%)

Query: 40  GYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPG 99
           GY     + G G  SY S G          S    YGS GG         SYG      G
Sbjct: 524 GYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG---------SYGSGGGGGG 574

Query: 100 YGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159
           +          GSYGS S S  Y     G        GG   S G+              
Sbjct: 575 H----------GSYGSGSSSGGYRGGSGG--------GGGGSSGGR-------------- 602

Query: 160 QYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS 190
                SGGG  GG  G  G     + S GGS
Sbjct: 603 ----GSGGGSSGGSIGGRGSSSGGVKSSGGS 629



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 37/111 (33%), Positives = 44/111 (39%), Gaps = 7/111 (6%)

Query: 14  YGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG-YGTQSTP 72
           YG+  +  G G     S   G      Y     + G G  SY S G     G YG+ S+ 
Sbjct: 525 YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584

Query: 73  QGY--GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS 121
            GY  GS GG G S   + S G  S     G      S+SG   SS  SSS
Sbjct: 585 GGYRGGSGGGGGGSSGGRGSGGGSSG----GSIGGRGSSSGGVKSSGGSSS 631



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 24/46 (52%), Positives = 26/46 (56%), Gaps = 9/46 (19%)

Query: 378 GGGNGRGGRGRGG----PMGRGGYGGGG-SGGGGRGGF----PSGG 414
           GGG G GG G GG      G GG+GGGG  GGG  GG+    P GG
Sbjct: 106 GGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 22/62 (35%), Positives = 23/62 (37%), Gaps = 4/62 (6%)

Query: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272
           R G   GG    G  G   Y R +     R  GGG    GG   S  GG   FG     G
Sbjct: 8   RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGG----GGRFSSCGGGGGSFGAGGGFG 63

Query: 273 SR 274
           SR
Sbjct: 64  SR 65


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 83/263 (31%), Positives = 103/263 (39%), Gaps = 56/263 (21%)

Query: 33  YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGY-----GSTGGYGSSQSS 87
           +G  ++ GY  +    G G  SY   G S   GY    +  G+     G  GG G   S 
Sbjct: 661 FGGANHGGYMNA----GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 716

Query: 88  QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY-GQQ 146
             SY Q  +Y      P P   +G            QP  G   Q+PSYG   QS+ GQQ
Sbjct: 717 YGSYYQGDNY----NSPVPPKHAGKK----------QPHGGQ--QKPSYGSGYQSHQGQQ 760

Query: 147 QSYN--------PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQD 198
           QSYN        PPQG  +Q  YN          G G+Y    S  S GGG G  Y  + 
Sbjct: 761 QSYNQSPYSNYGPPQG--KQKGYNH---------GQGSYSYSNSYNSPGGGGGSDYNYES 809

Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258
           +    GSGG          R G G   G GG  YN  S G    G GGG   +G  GG  
Sbjct: 810 KFNYSGSGG----------RSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 858

Query: 259 RGGFNKFGGPRDQGSRHDSEQDN 281
           +  +N  G  ++      S Q +
Sbjct: 859 QSNYNSPGSGQNYSGPPSSYQSS 881



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 84/250 (33%), Positives = 104/250 (41%), Gaps = 56/250 (22%)

Query: 49  GYGQSSYSSYGQSQNTGYGTQSTPQGYG---STGGYGSSQSSQSSYGQQSSYPGYGQQPA 105
           G+G +++  Y  +   GYG+     GYG   +T GY    S+    G  S   G G    
Sbjct: 660 GFGGANHGGY-MNAGAGYGSY----GYGGNSATAGYSQFYSNGGHSGNASGGGGGG---- 710

Query: 106 PSSTSGSYGSSSQSSSYGQPQSGSYS--QQPSYGGQQQSY--------GQQQSYN----- 150
               S  YGS  Q  +Y  P    ++  +QP  G Q+ SY        GQQQSYN     
Sbjct: 711 -GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 769

Query: 151 ---PPQG-----------YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196
              PPQG           Y   N YNS    GGGGG   NY    +   SGG SGG    
Sbjct: 770 NYGPPQGKQKGYNHGQGSYSYSNSYNSP---GGGGGSDYNYESKFNYSGSGGRSGG---- 822

Query: 197 QDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGGYNRSSGGYEPRGRGGGRGGRGGM 254
              S G G   Y     GG G GGSGGG    G  GGY++S+  Y   G G    G    
Sbjct: 823 --NSYGSGGASYNPGSHGGYG-GGSGGGSSYQGKQGGYSQSN--YNSPGSGQNYSGPPSS 877

Query: 255 GGSDRGGFNK 264
             S +GG+ +
Sbjct: 878 YQSSQGGYGR 887



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 76/234 (32%), Positives = 88/234 (37%), Gaps = 51/234 (21%)

Query: 10  ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG------QSSYSSYGQSQN 63
           A   YG+Y      GY   S+     Q YS    S + SG G       S Y SY Q  N
Sbjct: 672 AGAGYGSY------GYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDN 725

Query: 64  TG-------------YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ-QPAPSST 109
                          +G Q  P  YGS  GY S Q  Q SY Q S Y  YG  Q      
Sbjct: 726 YNSPVPPKHAGKKQPHGGQQKPS-YGS--GYQSHQGQQQSYNQ-SPYSNYGPPQGKQKGY 781

Query: 110 SGSYGSSSQSSSYGQPQSG-----SYSQQPSYGGQQ-----QSYGQQ-QSYNPPQ--GYG 156
           +   GS S S+SY  P  G     +Y  + +Y G        SYG    SYNP    GYG
Sbjct: 782 NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYG 841

Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210
             +   SS  G  GG    NY        +  GSG  Y     S     GGYG+
Sbjct: 842 GGSGGGSSYQGKQGGYSQSNY--------NSPGSGQNYSGPPSSYQSSQGGYGR 887



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 72/317 (22%)

Query: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
           G P+  +    P +G     + +     PP   G+    +    G G G GG N+G   +
Sbjct: 614 GGPKFAAKPHNPGFGMGGPMHNEVPP--PPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN 671

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           +       G GYG+    G   + GY Q    G   G + GGGGGGGGG    S GY   
Sbjct: 672 A-------GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGG----SSGYGSY 720

Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNS-DNNTIFVQGLGENVTIE 299
            +G                +N    P+  G +  H  +Q  S  +     QG  ++    
Sbjct: 721 YQG--------------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQS 766

Query: 300 SVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD---DPPSAKAAIDW-FD 355
             ++Y             G P       ++ G   G+ + S+    + P      D+ ++
Sbjct: 767 PYSNY-------------GPPQ-----GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 808

Query: 356 GK-EFSGNPIKVSFATRRADFNRGGGNGRGGRGRG-GPMGRGGYGGGGSGG----GGRGG 409
            K  +SG+              R GGN  G  G    P   GGYGGG  GG    G +GG
Sbjct: 809 SKFNYSGSG------------GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG 856

Query: 410 FPSG--GGGGGGQQRAG 424
           +        G GQ  +G
Sbjct: 857 YSQSNYNSPGSGQNYSG 873



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 63/240 (26%), Positives = 86/240 (35%), Gaps = 43/240 (17%)

Query: 98  PGYGQQPAPSST-----SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152
           P + + P P +       GS     +   +G    G Y    +  G     G   +    
Sbjct: 632 PMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS 691

Query: 153 QGYGQQNQYNSSSGGGGGGGGG----GNYGQDQSSMS------------SGGGSGGGYGN 196
           Q Y       ++SGGGGGGGGG    G+Y Q  +  S             GG     YG+
Sbjct: 692 QFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS 751

Query: 197 QDQSGGGGSGGYGQQDRG------GRGRGGSGG------------GGGGGGGGYNRSSGG 238
             QS  G    Y Q          G+ +G + G             GGGGG  YN  S  
Sbjct: 752 GYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYES-K 810

Query: 239 YEPRGRGGGRGGRG-GMGGS--DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295
           +   G GG  GG   G GG+  + G    +GG    GS +  +Q     +     G G+N
Sbjct: 811 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 870



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 46/142 (32%), Positives = 56/142 (39%), Gaps = 28/142 (19%)

Query: 6   YTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSY------- 58
           Y Q    +YG     P QG  +Q    +GQ SYS YS S ++ G G  S  +Y       
Sbjct: 763 YNQSPYSNYG-----PPQG--KQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYS 814

Query: 59  ---GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
              G+S    YG+       GS GGYG      SSY  Q    GY Q         +Y S
Sbjct: 815 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQ--------SNYNS 864

Query: 116 SSQSSSYGQPQSGSYSQQPSYG 137
                +Y  P S   S Q  YG
Sbjct: 865 PGSGQNYSGPPSSYQSSQGGYG 886



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 58/217 (26%), Positives = 68/217 (31%), Gaps = 83/217 (38%)

Query: 377 RGGGNGRGGRGRGGPMGRG-GYGGGGSGG-------------GGRGGFPSGGGGG----- 417
           RG G G GG   GG M  G GYG  G GG             GG  G  SGGGGG     
Sbjct: 655 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 714

Query: 418 ---------------------------GGQQRAG---------------------DWKCP 429
                                      GGQQ+                       ++  P
Sbjct: 715 SGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP 774

Query: 430 NPTCENMN-----FSWRNECNQCKAPKPDGPGGGPGGSHMGGNY-GDDRRGGRGGYDRGG 483
               +  N     +S+ N  N      P G GG         NY G   R G   Y  GG
Sbjct: 775 QGKQKGYNHGQGSYSYSNSYNS-----PGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG 829

Query: 484 YRGRGGDRGGFRGGRGGGD-----RGGFGPGKMDSRG 515
                G  GG+ GG GGG      +GG+     +S G
Sbjct: 830 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 866



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 5   DYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT 64
           +Y+    +S G      G  Y+  S   YG  S  G S      GY QS+Y+S G  QN 
Sbjct: 812 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 871

Query: 65  GYGTQSTPQGYGSTGGYGSSQSSQSSY 91
             G  S+ Q   S GGYG +     +Y
Sbjct: 872 S-GPPSSYQ--SSQGGYGRNADHSMNY 895



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%)

Query: 449 APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG-YRGRGGDRGGFRGGRGGGDRGGFG 507
           A KP  PG G GG             GRG   RGG  RGRG  RG      GG    G G
Sbjct: 619 AAKPHNPGFGMGGPMHNEVPPPPNLRGRG---RGGSIRGRGRGRGFGGANHGGYMNAGAG 675

Query: 508 PG 509
            G
Sbjct: 676 YG 677


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 83/263 (31%), Positives = 103/263 (39%), Gaps = 56/263 (21%)

Query: 33  YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGY-----GSTGGYGSSQSS 87
           +G  ++ GY  +    G G  SY   G S   GY    +  G+     G  GG G   S 
Sbjct: 657 FGGANHGGYMNA----GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 712

Query: 88  QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY-GQQ 146
             SY Q  +Y      P P   +G            QP  G   Q+PSYG   QS+ GQQ
Sbjct: 713 YGSYYQGDNY----NSPVPPKHAGKK----------QPHGGQ--QKPSYGSGYQSHQGQQ 756

Query: 147 QSYN--------PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQD 198
           QSYN        PPQG  +Q  YN          G G+Y    S  S GGG G  Y  + 
Sbjct: 757 QSYNQSPYSNYGPPQG--KQKGYNH---------GQGSYSYSNSYNSPGGGGGSDYNYES 805

Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258
           +    GSGG          R G G   G GG  YN  S G    G GGG   +G  GG  
Sbjct: 806 KFNYSGSGG----------RSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854

Query: 259 RGGFNKFGGPRDQGSRHDSEQDN 281
           +  +N  G  ++      S Q +
Sbjct: 855 QSNYNSPGSGQNYSGPPSSYQSS 877



 Score = 93.2 bits (230), Expect = 5e-19
 Identities = 84/250 (33%), Positives = 104/250 (41%), Gaps = 56/250 (22%)

Query: 49  GYGQSSYSSYGQSQNTGYGTQSTPQGYG---STGGYGSSQSSQSSYGQQSSYPGYGQQPA 105
           G+G +++  Y  +   GYG+     GYG   +T GY    S+    G  S   G G    
Sbjct: 656 GFGGANHGGY-MNAGAGYGSY----GYGGNSATAGYSQFYSNGGHSGNASGGGGGG---- 706

Query: 106 PSSTSGSYGSSSQSSSYGQPQSGSYS--QQPSYGGQQQSY--------GQQQSYN----- 150
               S  YGS  Q  +Y  P    ++  +QP  G Q+ SY        GQQQSYN     
Sbjct: 707 -GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 765

Query: 151 ---PPQG-----------YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196
              PPQG           Y   N YNS    GGGGG   NY    +   SGG SGG    
Sbjct: 766 NYGPPQGKQKGYNHGQGSYSYSNSYNSP---GGGGGSDYNYESKFNYSGSGGRSGG---- 818

Query: 197 QDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGGYNRSSGGYEPRGRGGGRGGRGGM 254
              S G G   Y     GG G GGSGGG    G  GGY++S+  Y   G G    G    
Sbjct: 819 --NSYGSGGASYNPGSHGGYG-GGSGGGSSYQGKQGGYSQSN--YNSPGSGQNYSGPPSS 873

Query: 255 GGSDRGGFNK 264
             S +GG+ +
Sbjct: 874 YQSSQGGYGR 883



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 76/234 (32%), Positives = 88/234 (37%), Gaps = 51/234 (21%)

Query: 10  ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG------QSSYSSYGQSQN 63
           A   YG+Y      GY   S+     Q YS    S + SG G       S Y SY Q  N
Sbjct: 668 AGAGYGSY------GYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDN 721

Query: 64  TG-------------YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ-QPAPSST 109
                          +G Q  P  YGS  GY S Q  Q SY Q S Y  YG  Q      
Sbjct: 722 YNSPVPPKHAGKKQPHGGQQKPS-YGS--GYQSHQGQQQSYNQ-SPYSNYGPPQGKQKGY 777

Query: 110 SGSYGSSSQSSSYGQPQSG-----SYSQQPSYGGQQ-----QSYGQQ-QSYNPPQ--GYG 156
           +   GS S S+SY  P  G     +Y  + +Y G        SYG    SYNP    GYG
Sbjct: 778 NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYG 837

Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210
             +   SS  G  GG    NY        +  GSG  Y     S     GGYG+
Sbjct: 838 GGSGGGSSYQGKQGGYSQSNY--------NSPGSGQNYSGPPSSYQSSQGGYGR 883



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 72/317 (22%)

Query: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
           G P+  +    P +G     + +     PP   G+    +    G G G GG N+G   +
Sbjct: 610 GGPKFAAKPHNPGFGMGGPMHNEVPP--PPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN 667

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           +       G GYG+    G   + GY Q    G   G + GGGGGGGGG    S GY   
Sbjct: 668 A-------GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGG----SSGYGSY 716

Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNS-DNNTIFVQGLGENVTIE 299
            +G                +N    P+  G +  H  +Q  S  +     QG  ++    
Sbjct: 717 YQG--------------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQS 762

Query: 300 SVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD---DPPSAKAAIDW-FD 355
             ++Y             G P       ++ G   G+ + S+    + P      D+ ++
Sbjct: 763 PYSNY-------------GPPQ-----GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 804

Query: 356 GK-EFSGNPIKVSFATRRADFNRGGGNGRGGRGRG-GPMGRGGYGGGGSGG----GGRGG 409
            K  +SG+              R GGN  G  G    P   GGYGGG  GG    G +GG
Sbjct: 805 SKFNYSGSG------------GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG 852

Query: 410 FPSG--GGGGGGQQRAG 424
           +        G GQ  +G
Sbjct: 853 YSQSNYNSPGSGQNYSG 869



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 63/240 (26%), Positives = 86/240 (35%), Gaps = 43/240 (17%)

Query: 98  PGYGQQPAPSST-----SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152
           P + + P P +       GS     +   +G    G Y    +  G     G   +    
Sbjct: 628 PMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS 687

Query: 153 QGYGQQNQYNSSSGGGGGGGGG----GNYGQDQSSMS------------SGGGSGGGYGN 196
           Q Y       ++SGGGGGGGGG    G+Y Q  +  S             GG     YG+
Sbjct: 688 QFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS 747

Query: 197 QDQSGGGGSGGYGQQDRG------GRGRGGSGG------------GGGGGGGGYNRSSGG 238
             QS  G    Y Q          G+ +G + G             GGGGG  YN  S  
Sbjct: 748 GYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYES-K 806

Query: 239 YEPRGRGGGRGGRG-GMGGS--DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295
           +   G GG  GG   G GG+  + G    +GG    GS +  +Q     +     G G+N
Sbjct: 807 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 866



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 46/142 (32%), Positives = 56/142 (39%), Gaps = 28/142 (19%)

Query: 6   YTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSY------- 58
           Y Q    +YG     P QG  +Q    +GQ SYS YS S ++ G G  S  +Y       
Sbjct: 759 YNQSPYSNYG-----PPQG--KQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYS 810

Query: 59  ---GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
              G+S    YG+       GS GGYG      SSY  Q    GY Q         +Y S
Sbjct: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQ--------SNYNS 860

Query: 116 SSQSSSYGQPQSGSYSQQPSYG 137
                +Y  P S   S Q  YG
Sbjct: 861 PGSGQNYSGPPSSYQSSQGGYG 882



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 58/217 (26%), Positives = 68/217 (31%), Gaps = 83/217 (38%)

Query: 377 RGGGNGRGGRGRGGPMGRG-GYGGGGSGG-------------GGRGGFPSGGGGG----- 417
           RG G G GG   GG M  G GYG  G GG             GG  G  SGGGGG     
Sbjct: 651 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 710

Query: 418 ---------------------------GGQQRAG---------------------DWKCP 429
                                      GGQQ+                       ++  P
Sbjct: 711 SGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP 770

Query: 430 NPTCENMN-----FSWRNECNQCKAPKPDGPGGGPGGSHMGGNY-GDDRRGGRGGYDRGG 483
               +  N     +S+ N  N      P G GG         NY G   R G   Y  GG
Sbjct: 771 QGKQKGYNHGQGSYSYSNSYNS-----PGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG 825

Query: 484 YRGRGGDRGGFRGGRGGGD-----RGGFGPGKMDSRG 515
                G  GG+ GG GGG      +GG+     +S G
Sbjct: 826 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 862



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 5   DYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT 64
           +Y+    +S G      G  Y+  S   YG  S  G S      GY QS+Y+S G  QN 
Sbjct: 808 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867

Query: 65  GYGTQSTPQGYGSTGGYGSSQSSQSSY 91
             G  S+ Q   S GGYG +     +Y
Sbjct: 868 S-GPPSSYQ--SSQGGYGRNADHSMNY 891



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%)

Query: 449 APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG-YRGRGGDRGGFRGGRGGGDRGGFG 507
           A KP  PG G GG             GRG   RGG  RGRG  RG      GG    G G
Sbjct: 615 AAKPHNPGFGMGGPMHNEVPPPPNLRGRG---RGGSIRGRGRGRGFGGANHGGYMNAGAG 671

Query: 508 PG 509
            G
Sbjct: 672 YG 673


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 80/240 (33%), Positives = 109/240 (45%), Gaps = 41/240 (17%)

Query: 273 SRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330
           SR DS +  +      +FV GL  +V    + ++F Q G ++  +        +  D+++
Sbjct: 84  SREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE--------IIADKQS 135

Query: 331 GKLKGEATVSFDDPPSA-KAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG------- 382
           GK +G   V F +  +A KAA+  F      G+ ++V  A  + D   GGG G       
Sbjct: 136 GKKRGFGFVYFQNHDAADKAAVVKFH--PIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRG 193

Query: 383 -RGGRGRGGP-----MGRGGYGG----GGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPT 432
            RGGRGRGG      + +GG GG    GG GGGG GG+ + GGGGGG    G     +  
Sbjct: 194 GRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGS----DYG 249

Query: 433 CENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRG 492
                F   ++      P   G GGG GGS  GG      R   G Y RGGY G GG  G
Sbjct: 250 NGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGG------RSNSGPY-RGGYGGGGGYGG 302



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 52/114 (45%), Positives = 59/114 (51%), Gaps = 13/114 (11%)

Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR--GG 220
           SS GG GG G GG  G+DQ+ +S GGG  GGY +    GGGG GGY     GG G   GG
Sbjct: 190 SSRGGRGGRGRGG--GRDQNGLSKGGG--GGYNSYGGYGGGGGGGYNAYGGGGGGSSYGG 245

Query: 221 SG-GGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM------GGSDRGGFNKFGG 267
           S  G G GG G Y++    Y P   GGG GG G         G  RGG+   GG
Sbjct: 246 SDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGG 299



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 57/133 (42%), Positives = 64/133 (48%), Gaps = 19/133 (14%)

Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN-YGQDQSSMSS 186
           GS S +   GG+ +  G+ Q+     G G    YNS  G GGGGGGG N YG        
Sbjct: 187 GSRSSRGGRGGRGRGGGRDQNGLSKGGGGG---YNSYGGYGGGGGGGYNAYG-------- 235

Query: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG--GYNRSSGGYEPRGR 244
           GGG G  YG  D   G G  G   Q +   G   SGGGGGGGG   G   +SG Y     
Sbjct: 236 GGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYR---- 291

Query: 245 GGGRGGRGGMGGS 257
            GG GG GG GGS
Sbjct: 292 -GGYGGGGGYGGS 303



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 39/86 (45%), Positives = 43/86 (50%), Gaps = 15/86 (17%)

Query: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGS----GGGGGGGGGGYNRSSGGYEP 241
           SGGG GG   ++   GG G GG   Q+   +G GG     GG GGGGGGGYN   GG   
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG--- 237

Query: 242 RGRGGGRGGRGGMGGSDRG-GFNKFG 266
                  GG    GGSD G GF  FG
Sbjct: 238 -------GGGSSYGGSDYGNGFGGFG 256



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 51/141 (36%), Positives = 61/141 (43%), Gaps = 29/141 (20%)

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ--- 133
           S GG G S+SS+   G +    G  Q        G Y S      YG    G Y+     
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYG---GYGGGGGGGYNAYGGG 237

Query: 134 ---PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG----GGGGGGGGGNYGQDQSSMSS 186
               SYGG    YG     N   G+G  +Q+ SS G    GGGGGGGG ++G      S+
Sbjct: 238 GGGSSYGGS--DYG-----NGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWG----GRSN 286

Query: 187 GGGSGGGYGNQDQSGGGGSGG 207
            G   GGYG     GGGG GG
Sbjct: 287 SGPYRGGYG-----GGGGYGG 302



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 33/82 (40%), Positives = 37/82 (45%), Gaps = 12/82 (14%)

Query: 200 SGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR 259
           SGGGG G           RGG GG G GGG   N  S     +G GGG    GG GG   
Sbjct: 181 SGGGGGGSRSS-------RGGRGGRGRGGGRDQNGLS-----KGGGGGYNSYGGYGGGGG 228

Query: 260 GGFNKFGGPRDQGSRHDSEQDN 281
           GG+N +GG     S   S+  N
Sbjct: 229 GGYNAYGGGGGGSSYGGSDYGN 250



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/72 (41%), Positives = 33/72 (45%), Gaps = 16/72 (22%)

Query: 450 PKPD---GPGGGPGGSHMGGNYGDDRRGGR----------GGYDR-GGYRGRGGDRGGFR 495
           PK D   G GGG   S  GG  G  R GGR          GGY+  GGY G GG  GG+ 
Sbjct: 175 PKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGG--GGYN 232

Query: 496 GGRGGGDRGGFG 507
              GGG    +G
Sbjct: 233 AYGGGGGGSSYG 244



 Score = 35.8 bits (81), Expect = 0.099
 Identities = 19/33 (57%), Positives = 20/33 (60%), Gaps = 3/33 (9%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF 410
           GGG+  GGR   GP  RGGYGGGG  G G   F
Sbjct: 276 GGGSSWGGRSNSGPY-RGGYGGGG--GYGGSSF 305



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 13/85 (15%)

Query: 13  SYGAYPTQPGQGYSQQSS----QPYGQQSYS-------GYSQSTDTSGYGQSSYSSYGQS 61
           SYG Y    G GY+          YG   Y         YSQ   + G  +S     G  
Sbjct: 219 SYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGG 278

Query: 62  QNTGYGTQSTPQ--GYGSTGGYGSS 84
            + G  + S P   GYG  GGYG S
Sbjct: 279 SSWGGRSNSGPYRGGYGGGGGYGGS 303


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 76/244 (31%), Positives = 100/244 (40%), Gaps = 38/244 (15%)

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
           ++GG+G   S     GQ    PG    P     P +++GS+G + Q + +GQ      P 
Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203

Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
            G+ +Q    QP YG  + S   +   NPP          S SGGG    GGG+  Q   
Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           S SSG GS G   N   SGG  SG       GG   G SG  GG  G   + SS G    
Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311

Query: 243 GRGGGRGGRGGMGGSDRG-----------GFNKFGGPRDQGSRHDSEQDNSDNNTIFVQG 291
              G  GG GG  G   G           G +   G R QG   +  + + + N + + G
Sbjct: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL-LGG 370

Query: 292 LGEN 295
            G+N
Sbjct: 371 SGDN 374



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)

Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
           G   G GG+G+G P G G     GY G  +G  G    G P G GG GG    G      
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211

Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
              P   ++  S +NE   C  P P G GGG    G   G   G    G  G  + G   
Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269

Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
           G    G   GG  GG  GG  G  G  + DS  E
Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 60/196 (30%), Positives = 72/196 (36%), Gaps = 20/196 (10%)

Query: 32  PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89
           P+GQ    G     T+T G   Q  Y S   S      T   P G G     G S +S  
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246

Query: 90  SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147
             G QS   G G     +  S+SG   SSS SSS G     S     + GG +   G + 
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304

Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207
           S+    G        SSSG  GG GGG  +        +     G  G Q   G G S  
Sbjct: 305 SWGSSTG--------SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356

Query: 208 YGQ-QDRGGRGRGGSG 222
             +    G R  GGSG
Sbjct: 357 MREISKEGNRLLGGSG 372



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 60/197 (30%), Positives = 79/197 (40%), Gaps = 24/197 (12%)

Query: 11  TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
           T + GA   QPG G  + S+Q  G         +   SG G  S +S G     G G+QS
Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252

Query: 71  TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQSG 128
              G GS G   +  SS  S    SS    G     SS  + GS G S   SS+G   S 
Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG---SS 309

Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG- 187
           + S   ++GG     G +     P   G + + +  SG  G  G G +    + S     
Sbjct: 310 TGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMREISKEGNR 366

Query: 188 --GGSGGGYGNQDQSGG 202
             GGSG  Y N + S G
Sbjct: 367 LLGGSGDNYRNSETSPG 383



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%)

Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
           G+G  +  +   G   G   GG  G   S ++  G     G G +   G G +   G + 
Sbjct: 40  GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99

Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
                  G +G   G               G   G    +G +E  G  G  G +GG+GG
Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
             +G     G P   G   +S      N      G G N    +            TN +
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209

Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
                    + R + + +G      + PPS         G   SG               
Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247

Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
            G  +G  G G  G    G   GG S G   GG  SGG  GG    +G  +  +      
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
             SW +           G   G  G   GGN      G + G ++ G   RG    G +G
Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347

Query: 497 GRGGG 501
            RG G
Sbjct: 348 FRGQG 352



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%)

Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414
           GN  G  G   +G P G+GG GG  + G    G                       PSG 
Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237

Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468
           GGG      G       +    N    N  +   +      GG  GGS      + GG+ 
Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297

Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505
           GD       G   G   G  G  GG  G + G ++ G
Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 91/396 (22%), Positives = 129/396 (32%), Gaps = 51/396 (12%)

Query: 78  TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
           +G  G  QS + S G       G+G   A S   G         + G   S +  Q    
Sbjct: 18  SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73

Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188
            G +++ G      P  G+G  +   +  G      G  G   G+    +   G      
Sbjct: 74  -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130

Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
              G  G  G  + SGG G  G  Q   GG+G+G  GG G     GY  +S G       
Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189

Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
           G   G+GG GG    G N  G     G    R  ++ +   N      G G +    S  
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS---NSGG 246

Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
               Q G    +  +G    N       G   G ++       S  ++ +    +  SG+
Sbjct: 247 GSGSQSG----SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302

Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGG-------- 414
                 +T  +  N GG    GG G      + G    GSG  G  GF   G        
Sbjct: 303 ESSWGSSTGSSSGNHGGSG--GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360

Query: 415 --------GGGGGQQRAGDWKCPNPTCENMNFSWRN 442
                   GG G   R  +    +P   N +  W+N
Sbjct: 361 SKEGNRLLGGSGDNYRNSE---TSPGMFNFDTFWKN 393


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score = 92.4 bits (228), Expect = 9e-19
 Identities = 69/188 (36%), Positives = 86/188 (45%), Gaps = 29/188 (15%)

Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGG 174
           +S+ SS  G+  SG++      GG+   +G   ++     +  +  +  S GGGG GG G
Sbjct: 187 ASASSSQRGRSGSGNFG-----GGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSG 241

Query: 175 GNY------------GQDQSSMSSGGGSGG-GYGNQDQSGGGGSGGYGQQDRGGRG--RG 219
             Y            G   S  S G GSGG GYGNQ  SG GGSG Y   + GG G   G
Sbjct: 242 DGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQG-SGYGGSGSYDSYNNGGGGGFGG 300

Query: 220 GSGGGGGGGG-----GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR 274
           GSG   GGGG     G YN  S  + P  +GG  GGR    G   GG   F  PR+QG  
Sbjct: 301 GSGSNFGGGGSYNDFGNYNNQSSNFGPM-KGGNFGGRS--SGPYGGGGQYFAKPRNQGGY 357

Query: 275 HDSEQDNS 282
             S   +S
Sbjct: 358 GGSSSSSS 365



 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 85/271 (31%), Positives = 117/271 (43%), Gaps = 41/271 (15%)

Query: 268 PRDQGSRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325
           P+   SR DS++  +      IFV G+ E+     + DYF+Q G I+        +I + 
Sbjct: 86  PKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIM 137

Query: 326 TDRETGKLKGEATVSFDDPPSA-KAAIDWFDG---------KEFSGNPIKVSFATRRA-- 373
           TDR +GK +G A V+FDD  S  K  I  +           K  S   +  + +++R   
Sbjct: 138 TDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRS 197

Query: 374 ---DFNRGGGNGRGGR---GRGGPM-GRGGYGG----GGSGGGGRG--GFPSGGG-GGGG 419
              +F  G G G GG    GRGG   GRGG+GG    GG GG G G  GF + GG GGGG
Sbjct: 198 GSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGG 257

Query: 420 QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY 479
              +G  +      +                  +  GGG  G   G N+G    GG    
Sbjct: 258 PGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFG----GGGSYN 313

Query: 480 DRGGYRGRGGDRGGFRGGR-GGGDRGGFGPG 509
           D G Y  +  + G  +GG  GG   G +G G
Sbjct: 314 DFGNYNNQSSNFGPMKGGNFGGRSSGPYGGG 344



 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 67/210 (31%), Positives = 83/210 (39%), Gaps = 45/210 (21%)

Query: 44  STDTSGYGQSSYSSYGQSQNTGYGTQST---PQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100
           S  +S  G+S   ++G  +  G+G          +   GG+G S+      G    Y G+
Sbjct: 188 SASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGF 247

Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ 160
           G         G YG      S G    GS  Q   YG Q   YG         G G  + 
Sbjct: 248 GND-------GGYGGGGPGYSGGSRGYGSGGQ--GYGNQGSGYG---------GSGSYDS 289

Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG---GGYGNQDQSGGGGSGGYGQQDRGGRG 217
           YN+  GGG GGG G N+G        GGGS    G Y NQ  + G   GG    + GGR 
Sbjct: 290 YNNGGGGGFGGGSGSNFG--------GGGSYNDFGNYNNQSSNFGPMKGG----NFGGRS 337

Query: 218 RGGSGGGG---------GGGGGGYNRSSGG 238
            G  GGGG         GG GG  + SS G
Sbjct: 338 SGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 66/232 (28%), Positives = 80/232 (34%), Gaps = 50/232 (21%)

Query: 1   MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ--SYSGYSQSTDTSGYGQSSYSSY 58
           MAS   +Q+     G +    G G+    +   G       G+  S    GYG S     
Sbjct: 186 MASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS----- 240

Query: 59  GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQ 118
                 GY       G+G+ GGYG               PGY        + GS G  S 
Sbjct: 241 ----GDGY------NGFGNDGGYGGGG------------PGY--------SGGSRGYGSG 270

Query: 119 SSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178
              YG   SG       YGG     G   SYN   G G      S+ GGGG     GNY 
Sbjct: 271 GQGYGNQGSG-------YGGS----GSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYN 319

Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG 230
              S+   G   GG +G +     GG G Y  + R   G GGS      G G
Sbjct: 320 NQSSNF--GPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 44/99 (44%), Positives = 49/99 (49%), Gaps = 7/99 (7%)

Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG---GGGGYNRS 235
           Q+ +S SS      G GN    GGG  GG+G  D  GRG   SG GG G   GGGGY  S
Sbjct: 184 QEMASASSSQRGRSGSGN---FGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 240

Query: 236 SGGYEPRGRGGGRGGRG-GMGGSDRGGFNKFGGPRDQGS 273
             GY   G  GG GG G G  G  RG  +   G  +QGS
Sbjct: 241 GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGS 279



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 41/127 (32%), Positives = 47/127 (37%), Gaps = 14/127 (11%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437
           GGG G  G  RG   G  GYG  GSG GG G + S   GGGG    G            N
Sbjct: 255 GGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGG---------SGSN 305

Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGG 497
           F      N            GP     GGN+G    G  GG   G Y  +  ++GG+ G 
Sbjct: 306 FGGGGSYNDFGNYNNQSSNFGP---MKGGNFGGRSSGPYGG--GGQYFAKPRNQGGYGGS 360

Query: 498 RGGGDRG 504
                 G
Sbjct: 361 SSSSSYG 367



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 51/116 (43%)

Query: 375 FNRGGGNGRGGRGRGGPMGRGG--------------YG---GGGSGGGGRGGFPSGGGGG 417
           +N GGG G GG G G   G GG              +G   GG  GG   G +     GG
Sbjct: 290 YNNGGGGGFGG-GSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPY-----GG 343

Query: 418 GGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRR 473
           GGQ  A                 RN+             GG GGS    +YG  RR
Sbjct: 344 GGQYFAKP---------------RNQ-------------GGYGGSSSSSSYGSGRR 371


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 55/118 (46%), Positives = 62/118 (52%), Gaps = 21/118 (17%)

Query: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210
           PP+    Q +     G GG GGGGG           GGG GGG       GGGG GG+G 
Sbjct: 319 PPEMPPWQKRQEGGGGRGGWGGGGG-----------GGGRGGG------GGGGGRGGWG- 360

Query: 211 QDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG-SDRGGFNKFGG 267
              GG G GG GGGGGG GGG     GG++ RG  GGRGG GG GG   RG  + +GG
Sbjct: 361 --GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGG 416



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 63/132 (47%), Positives = 64/132 (48%), Gaps = 36/132 (27%)

Query: 379 GGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGG-GGGQQRAGDWKCPNPTCENMN 437
           GG GRGG G GG  G GG GGGG GGGGRGG+  GGGG GGG    G W           
Sbjct: 331 GGGGRGGWGGGG--GGGGRGGGG-GGGGRGGWGGGGGGWGGGGGGGGGW----------- 376

Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY-DRGGYRGRG-GDRGGFR 495
                              GG GG   GG  G    GGRGGY  RGGY GRG GD  G  
Sbjct: 377 -------------------GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417

Query: 496 GGRGGGDRGGFG 507
           GG GGG  GG G
Sbjct: 418 GGGGGGGGGGGG 429



 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 54/129 (41%), Positives = 66/129 (51%), Gaps = 19/129 (14%)

Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191
           + P +  +Q+  G +  +    G G +       G GG GGGGG +G        GGG G
Sbjct: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWG-------GGGGGG 373

Query: 192 GGYGNQDQSGGGGSGGY-GQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250
           GG+G     GGGG GG+ G+ D G  GRGG GG GG GG GY       +P G GGG GG
Sbjct: 374 GGWGG---GGGGGRGGFQGRGDYG--GRGGYGGRGGYGGRGYG------DPYGGGGGGGG 422

Query: 251 RGGMGGSDR 259
            GG GG  R
Sbjct: 423 GGGGGGGYR 431



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 45/89 (50%), Positives = 48/89 (53%), Gaps = 12/89 (13%)

Query: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGG 246
           GGG  GG+G     GGGG GG     RGG G GG  GG GGGGGG+    GG    G GG
Sbjct: 331 GGGGRGGWG-----GGGGGGG-----RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG-GG 379

Query: 247 GRGGRGG-MGGSDRGGFNKFGGPRDQGSR 274
           G GGRGG  G  D GG   +GG    G R
Sbjct: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 39/76 (51%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258
           Q GGGG        RGG G GG GGG GGGGGG  R   G    G GGG GG GG GG  
Sbjct: 329 QEGGGG--------RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380

Query: 259 RGGFNKFGGPRDQGSR 274
            GG   F G  D G R
Sbjct: 381 GGGRGGFQGRGDYGGR 396



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 32/54 (59%), Positives = 33/54 (61%), Gaps = 9/54 (16%)

Query: 378 GGGNGRGG-------RGRGGPMGRGGYGGGGSGG--GGRGGFPSGGGGGGGQQR 422
           GGG GRGG        GRGG  GRGGYGG G G   GG GG   GGGGGGG +R
Sbjct: 379 GGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 36/82 (43%), Positives = 42/82 (51%), Gaps = 10/82 (12%)

Query: 445 NQCKAPKPDGP--------GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
           N+ + P P+ P        GGG GG   GG  G  R GG GG  RGG+ G GG  GG  G
Sbjct: 313 NEIEPPPPEMPPWQKRQEGGGGRGG-WGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371

Query: 497 GRGG-GDRGGFGPGKMDSRGEH 517
           G GG G  GG G G    RG++
Sbjct: 372 GGGGWGGGGGGGRGGFQGRGDY 393



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 45/115 (39%), Positives = 47/115 (40%), Gaps = 50/115 (43%)

Query: 403 GGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462
           GGGGRGG+  GGGGGGG                                  G GGG GG 
Sbjct: 331 GGGGRGGW--GGGGGGG----------------------------------GRGGGGGG- 353

Query: 463 HMGGNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGDRGGF-GPGKMDSRG 515
                      GGRGG+  GG   G GG  GG  GG GGG RGGF G G    RG
Sbjct: 354 -----------GGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRG 397



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 31/66 (46%), Positives = 33/66 (50%), Gaps = 18/66 (27%)

Query: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGG----------GGSGG-GGRGGF-------PSG 413
           R  +  GGG   GG G GG  G GG GG          GG GG GGRGG+       P G
Sbjct: 356 RGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415

Query: 414 GGGGGG 419
           GGGGGG
Sbjct: 416 GGGGGG 421



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 33/126 (26%), Positives = 41/126 (32%), Gaps = 21/126 (16%)

Query: 69  QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128
           Q   +G G  GG+G                G G +       G  G       +G    G
Sbjct: 326 QKRQEGGGGRGGWGGGG-------------GGGGRGGGGGGGGRGGWGGGGGGWGGGGGG 372

Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
                   GG +  +  +  Y    GYG +  Y     G   GGGGG  G        GG
Sbjct: 373 GGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG--------GG 424

Query: 189 GSGGGY 194
           G GGGY
Sbjct: 425 GGGGGY 430


>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
          Length = 386

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 73/226 (32%), Positives = 95/226 (42%), Gaps = 28/226 (12%)

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
           ++GG+G   S     GQ    PG    P     P +++GS+G + Q + +GQ      P 
Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203

Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
            G+ +Q    QP YG  + S   +   NPP          S SGGG    GGG+  Q   
Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           S SSG GS G   N   SGG  SG       GG   G SG  GG  G   + SS G    
Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311

Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288
              G  GG GG G   + G  K  G   +GS     Q++  +  +F
Sbjct: 312 SSSGNHGGSGG-GNGHKPGCEK-PGNEARGSGESGIQNSETSPGMF 355



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)

Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
           G   G GG+G+G P G G     GY G  +G  G    G P G GG GG    G      
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211

Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
              P   ++  S +NE   C  P P G GGG    G   G   G    G  G  + G   
Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269

Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
           G    G   GG  GG  GG  G  G  + DS  E
Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 67/278 (24%), Positives = 97/278 (34%), Gaps = 39/278 (14%)

Query: 43  QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98
           +ST T+  G++     G + + G G     +  G+ G   S    Q ++ + G      P
Sbjct: 29  ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87

Query: 99  GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145
           G+G   A  +  G    +  ++ +                  GS+   P + G  ++ G 
Sbjct: 88  GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147

Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198
              +    G G Q Q N    G     G  G   G++G +      G G  GG  N   +
Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207

Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGG--GGGGGGYNRSSGGYEPRG---RGG 246
             G     GYG      +  G       GSGGG    GGG G    S G    G    G 
Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267

Query: 247 GRGG--RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
             GG   G   G   GG +        GSR DS  ++S
Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 52/175 (29%), Positives = 67/175 (38%), Gaps = 17/175 (9%)

Query: 32  PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89
           P+GQ    G     T+T G   Q  Y S   S      T   P G G     G S +S  
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246

Query: 90  SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147
             G QS   G G     +  S+SG   SSS SSS G     S     + GG +   G + 
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304

Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202
           S      +G     +S + GG GGG G   G ++    + G    G  N + S G
Sbjct: 305 S------WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 16/161 (9%)

Query: 11  TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
           T + GA   QPG G  + S+Q  G         +   SG G  S +S G     G G+QS
Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252

Query: 71  TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQ-S 127
              G GS G   +  SS  S    SS    G     SS  + GS G S   SS+G    S
Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312

Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
            S +   S GG     G ++  N  +G G+    NS +  G
Sbjct: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 79/359 (22%), Positives = 110/359 (30%), Gaps = 69/359 (19%)

Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
           G+G  +  +   G   G   GG  G   S ++  G     G G +   G G +   G + 
Sbjct: 40  GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99

Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
                  G +G   G               G   G    +G +E  G  G  G +GG+GG
Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
             +G     G P   G   +S      N      G G N    +            TN +
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209

Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
                    + R + + +G      + PPS         G   SG               
Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247

Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
            G  +G  G G  G    G   GG S G   GG  SGG  GG    +G  +  +      
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
             SW +           G   G  G   GGN      G + G ++ G   RG    G +
Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQ 346



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%)

Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414
           GN  G  G   +G P G+GG GG  + G    G                       PSG 
Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237

Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468
           GGG      G       +    N    N  +   +      GG  GGS      + GG+ 
Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297

Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505
           GD       G   G   G  G  GG  G + G ++ G
Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 83/381 (21%), Positives = 120/381 (31%), Gaps = 51/381 (13%)

Query: 78  TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
           +G  G  QS + S G       G+G   A S   G         + G   S +  Q    
Sbjct: 18  SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73

Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188
            G +++ G      P  G+G  +   +  G      G  G   G+    +   G      
Sbjct: 74  -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130

Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
              G  G  G  + SGG G  G  Q   GG+G+G  GG G     GY  +S G       
Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189

Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
           G   G+GG GG    G N  G     G    R  ++ +   N      G G + +     
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247

Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
                     +  ++G        D   G   G ++       S+  +     G   SG 
Sbjct: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--SGG 295

Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422
                        +RG        G       G +GG G G G + G    G    G   
Sbjct: 296 -------------SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342

Query: 423 AGDWKC-PNPTCENMNFSWRN 442
           +G      +P   N +  W+N
Sbjct: 343 SGIQNSETSPGMFNFDTFWKN 363


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 73/226 (32%), Positives = 95/226 (42%), Gaps = 28/226 (12%)

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
           ++GG+G   S     GQ    PG    P     P +++GS+G + Q + +GQ      P 
Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203

Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
            G+ +Q    QP YG  + S   +   NPP          S SGGG    GGG+  Q   
Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           S SSG GS G   N   SGG  SG       GG   G SG  GG  G   + SS G    
Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311

Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288
              G  GG GG G   + G  K  G   +GS     Q++  +  +F
Sbjct: 312 SSSGNHGGSGG-GNGHKPGCEK-PGNEARGSGESGIQNSETSPGMF 355



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)

Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
           G   G GG+G+G P G G     GY G  +G  G    G P G GG GG    G      
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211

Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
              P   ++  S +NE   C  P P G GGG    G   G   G    G  G  + G   
Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269

Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
           G    G   GG  GG  GG  G  G  + DS  E
Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 67/278 (24%), Positives = 97/278 (34%), Gaps = 39/278 (14%)

Query: 43  QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98
           +ST T+  G++     G + + G G     +  G+ G   S    Q ++ + G      P
Sbjct: 29  ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87

Query: 99  GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145
           G+G   A  +  G    +  ++ +                  GS+   P + G  ++ G 
Sbjct: 88  GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147

Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198
              +    G G Q Q N    G     G  G   G++G +      G G  GG  N   +
Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207

Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGG--GGGGGGYNRSSGGYEPRG---RGG 246
             G     GYG      +  G       GSGGG    GGG G    S G    G    G 
Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267

Query: 247 GRGG--RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
             GG   G   G   GG +        GSR DS  ++S
Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 52/175 (29%), Positives = 67/175 (38%), Gaps = 17/175 (9%)

Query: 32  PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89
           P+GQ    G     T+T G   Q  Y S   S      T   P G G     G S +S  
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246

Query: 90  SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147
             G QS   G G     +  S+SG   SSS SSS G     S     + GG +   G + 
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304

Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202
           S      +G     +S + GG GGG G   G ++    + G    G  N + S G
Sbjct: 305 S------WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 16/161 (9%)

Query: 11  TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70
           T + GA   QPG G  + S+Q  G         +   SG G  S +S G     G G+QS
Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252

Query: 71  TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQ-S 127
              G GS G   +  SS  S    SS    G     SS  + GS G S   SS+G    S
Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312

Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168
            S +   S GG     G ++  N  +G G+    NS +  G
Sbjct: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 79/359 (22%), Positives = 110/359 (30%), Gaps = 69/359 (19%)

Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
           G+G  +  +   G   G   GG  G   S ++  G     G G +   G G +   G + 
Sbjct: 40  GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99

Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
                  G +G   G               G   G    +G +E  G  G  G +GG+GG
Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
             +G     G P   G   +S      N      G G N    +            TN +
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209

Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
                    + R + + +G      + PPS         G   SG               
Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247

Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
            G  +G  G G  G    G   GG S G   GG  SGG  GG    +G  +  +      
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
             SW +           G   G  G   GGN      G + G ++ G   RG    G +
Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQ 346



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%)

Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414
           GN  G  G   +G P G+GG GG  + G    G                       PSG 
Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237

Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468
           GGG      G       +    N    N  +   +      GG  GGS      + GG+ 
Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297

Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505
           GD       G   G   G  G  GG  G + G ++ G
Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 83/381 (21%), Positives = 120/381 (31%), Gaps = 51/381 (13%)

Query: 78  TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136
           +G  G  QS + S G       G+G   A S   G         + G   S +  Q    
Sbjct: 18  SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73

Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188
            G +++ G      P  G+G  +   +  G      G  G   G+    +   G      
Sbjct: 74  -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130

Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245
              G  G  G  + SGG G  G  Q   GG+G+G  GG G     GY  +S G       
Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189

Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302
           G   G+GG GG    G N  G     G    R  ++ +   N      G G + +     
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247

Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362
                     +  ++G        D   G   G ++       S+  +     G   SG 
Sbjct: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--SGG 295

Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422
                        +RG        G       G +GG G G G + G    G    G   
Sbjct: 296 -------------SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342

Query: 423 AGDWKC-PNPTCENMNFSWRN 442
           +G      +P   N +  W+N
Sbjct: 343 SGIQNSETSPGMFNFDTFWKN 363


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 23  QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74
           Q   QQ  Q   QQ     S +    G G  +           +G ++++  G Q+ P G
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117

Query: 75  YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114
                  G    +    G+ +     +PG G    QQP  +   G             YG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177

Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156
           S++ +S     ++G    Q  +GGQQ             + G   S +P Q    GY   
Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213
           Q N Y   S    GGGGGGGGG           GGGSGGG G     GG G+GG G    
Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281

Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259
                  +   GGGGGGGY  SS GY     PR +GGG   G GG G         GS  
Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341

Query: 260 GGFNKFGGPRDQGS 273
           GGF +F G     S
Sbjct: 342 GGFQRFAGQNQHPS 355



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435
           N   G  R G G GG  G GG GGGGSGGGG GG    GG G G   A            
Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284

Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
                        A    G GGG GGS  G       R   GG   G     GG      
Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333

Query: 496 GGRGGGDRGGF 506
               G   GGF
Sbjct: 334 KAAAGSAAGGF 344



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%)

Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419
           ++R G  G GG G GG  G GG GGGG  G G  G              +GGGGGGG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85
           SQ   QP G QS        ++S +   S S   Q +    GTQ  PQ            
Sbjct: 704 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 743

Query: 86  SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145
              + YG Q + P     P+P     +  SS Q S+     SG+Y      G Q   YG 
Sbjct: 744 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 791

Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199
           Q +Y+ P  Y      + S  G G G    N  +GQ  S    ++  G     G  N+  
Sbjct: 792 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 851

Query: 200 SGGGGS---GGYGQQDRGGRGRG 219
            G   S      G   +GG G G
Sbjct: 852 PGNMSSMTPSSPGMSQQGGPGMG 874



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%)

Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438
           G      GGP GR G      GG    G G   S      G   + D        +N + 
Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230

Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494
            + N +CN        G GGG GG   GG       GG GG   GG  G GG   G    
Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283

Query: 495 --------RGGRGGGDRGGFGPG 509
                    GG GGG  GG   G
Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 74/289 (25%), Positives = 91/289 (31%), Gaps = 59/289 (20%)

Query: 6   YTQQATQSYGAYPTQPGQ---------GYSQQSSQPYGQQSYSGY-SQSTDTSGYGQSSY 55
           Y QQ  Q Y +   QP             SQQ  QP    S  GY ++S      G+ ++
Sbjct: 547 YCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH 606

Query: 56  SSY---------------GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQ------ 94
                             G   +   GT++T     S  G  SSQ  QS+  Q       
Sbjct: 607 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 666

Query: 95  ----SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYN 150
               SS PG    P+PS      GS+   S    P S   SQ P      QS   + S +
Sbjct: 667 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS---ESSSH 720

Query: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS------MSSGGGSGGGYGNQDQSGGGG 204
           P        Q      G         YG  Q+        S GG    G  +  QS   G
Sbjct: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780

Query: 205 SGG-----YGQQDRGGRGRGGSG-------GGGGGGGGGYNRSSGGYEP 241
           + G     YG Q    R    SG       G G G G   N    G  P
Sbjct: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGP 829



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%)

Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191
           QQ +   QQQ   QQQ     Q   QQ+  ++++  GG GGG    G D      GG   
Sbjct: 50  QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106

Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226
              G Q    G                 G    G+ +  G G  G+         GGGG 
Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166

Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
                +N   G   P    GG GGR G      GG
Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%)

Query: 21  PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78
           PG G    +   +     S    S    G     +  +G  Q+ G G    ++    G+ 
Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219

Query: 79  GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124
           G     Q+S   Y   Q + YPGY +  A     G  G    S   G             
Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279

Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179
               + + +   + GG    YG   +     GYG  +      GG   G GGGG  +  +
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201
             +  ++GG       NQ  SG
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%)

Query: 4   NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55
           N+Y   A  + G    + G  + Q   Q   Q    G   S   +  G        Q+S+
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229

Query: 56  SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
             Y  SQ   Y   S P   G  GG G         G      G G   A  + +G+  +
Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283

Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170
           ++ +++      G       YGG    YG     +QQ      G G     + S    G 
Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200
             GG     GQ+Q                   M S GGS   Y +           Q Q+
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223
              G+   GQQ   G G G   G
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%)

Query: 4    NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61
            N  T  A    G + P   G+   + +  P+G  +   G S+   T G   +S      +
Sbjct: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1253

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120
            Q+      +   G      YG+S   +   YGQQ  YPG G               S   
Sbjct: 1254 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1298

Query: 121  SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170
             YG  Q G Y QQP+Y       YG      +   YN      QQ  YN   G   G
Sbjct: 1299 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1355



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410
           GGG G GG G GG  G GG G G            +GGGG GG+                
Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316

Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437
                  P GGG             GG Q+ AG  + P+     +N
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 37/150 (24%), Positives = 45/150 (30%), Gaps = 23/150 (15%)

Query: 15  GAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST--- 71
           G+ P    Q  S      YG      Y         G  +   Y Q Q++G  T      
Sbjct: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533

Query: 72  --PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
             P  YG  G         S Y QQ   P Y QQP P              +   P    
Sbjct: 534 LMPPQYGQQG--------VSGYCQQGQQPYYSQQPQPPHL--------PPQAQYLPSQSQ 577

Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159
              QP     Q+ YG +    PP   G+ N
Sbjct: 578 QRYQPQQDMSQEGYGTRS--QPPLAPGKPN 605



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%)

Query: 22  GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76
           GQG SQ   + P G+   +G             + SS G SQ  G G      +  +   
Sbjct: 826 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 885

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135
                    ++ S+  +Q S+PG  Q    +S+S      + SSS    Q+  YS  P+
Sbjct: 886 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 944



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 45/190 (23%), Positives = 57/190 (30%), Gaps = 19/190 (10%)

Query: 10  ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60
           A  + G +    GQ      + P   Q  +  S    + G     YSS           Q
Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396

Query: 61  SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113
           SQ    G  +  Q   +  G G    +Q +         QQ S+P         +   S 
Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456

Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           GS        +PQ       P    QQ S     SY PP   G Q       G   G   
Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513

Query: 174 GGNYGQDQSS 183
           G  Y Q Q S
Sbjct: 514 GMQYPQQQDS 523



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%)

Query: 25   YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80
            YS Q  + Y Q   S YS        GQ  Y  Y + +  G G   T    PQ  G    
Sbjct: 1338 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1391

Query: 81   YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129
             G  QSS S   QQ+ +      P P       G  +Q+  Y              +   
Sbjct: 1392 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1450

Query: 130  YSQQPSYGGQQQSY-----GQQQSYNPPQ 153
             SQ PS+  Q+Q Y       Q    PPQ
Sbjct: 1451 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1479


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 23  QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74
           Q   QQ  Q   QQ     S +    G G  +           +G ++++  G Q+ P G
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117

Query: 75  YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114
                  G    +    G+ +     +PG G    QQP  +   G             YG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177

Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156
           S++ +S     ++G    Q  +GGQQ             + G   S +P Q    GY   
Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213
           Q N Y   S    GGGGGGGGG           GGGSGGG G     GG G+GG G    
Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281

Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259
                  +   GGGGGGGY  SS GY     PR +GGG   G GG G         GS  
Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341

Query: 260 GGFNKFGGPRDQGS 273
           GGF +F G     S
Sbjct: 342 GGFQRFAGQNQHPS 355



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435
           N   G  R G G GG  G GG GGGGSGGGG GG    GG G G   A            
Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284

Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
                        A    G GGG GGS  G       R   GG   G     GG      
Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333

Query: 496 GGRGGGDRGGF 506
               G   GGF
Sbjct: 334 KAAAGSAAGGF 344



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%)

Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419
           ++R G  G GG G GG  G GG GGGG  G G  G              +GGGGGGG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85
           SQ   QP G QS        ++S +   S S   Q +    GTQ  PQ            
Sbjct: 691 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 730

Query: 86  SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145
              + YG Q + P     P+P     +  SS Q S+     SG+Y      G Q   YG 
Sbjct: 731 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 778

Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199
           Q +Y+ P  Y      + S  G G G    N  +GQ  S    ++  G     G  N+  
Sbjct: 779 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 838

Query: 200 SGGGGS---GGYGQQDRGGRGRG 219
            G   S      G   +GG G G
Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMG 861



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%)

Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438
           G      GGP GR G      GG    G G   S      G   + D        +N + 
Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230

Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494
            + N +CN        G GGG GG   GG       GG GG   GG  G GG   G    
Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283

Query: 495 --------RGGRGGGDRGGFGPG 509
                    GG GGG  GG   G
Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 81/313 (25%), Positives = 92/313 (29%), Gaps = 80/313 (25%)

Query: 1   MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPY-----------------GQQSYSGYSQ 43
           MA   Y QQ  Q    Y  Q   GY QQ  QPY                   QS   Y  
Sbjct: 512 MAGMQYPQQ--QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP 569

Query: 44  STDTS--GYGQSSYSSY-------------------------GQSQNTGYGTQSTPQGYG 76
             D S  GYG  S                             G   +   GT++T     
Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629

Query: 77  STGGYGSSQSSQSSYGQQ----------SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126
           S  G  SSQ  QS+  Q           SS PG    P+PS      GS+   S    P 
Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPA 686

Query: 127 SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS--- 183
           S   SQ P      QS   + S +P        Q      G         YG  Q+    
Sbjct: 687 SIPGSQMPPQPPGSQS---ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743

Query: 184 ---MSSGGGSGGGYGNQDQSGGGGSGG-----YGQQDRGGRGRGGSG-------GGGGGG 228
               S GG    G  +  QS   G+ G     YG Q    R    SG       G G G 
Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803

Query: 229 GGGYNRSSGGYEP 241
           G   N    G  P
Sbjct: 804 GISANNQMHGQGP 816



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%)

Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191
           QQ +   QQQ   QQQ     Q   QQ+  ++++  GG GGG    G D      GG   
Sbjct: 50  QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106

Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226
              G Q    G                 G    G+ +  G G  G+         GGGG 
Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166

Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
                +N   G   P    GG GGR G      GG
Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%)

Query: 21  PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78
           PG G    +   +     S    S    G     +  +G  Q+ G G    ++    G+ 
Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219

Query: 79  GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124
           G     Q+S   Y   Q + YPGY +  A     G  G    S   G             
Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279

Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179
               + + +   + GG    YG   +     GYG  +      GG   G GGGG  +  +
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201
             +  ++GG       NQ  SG
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%)

Query: 4   NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55
           N+Y   A  + G    + G  + Q   Q   Q    G   S   +  G        Q+S+
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229

Query: 56  SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
             Y  SQ   Y   S P   G  GG G         G      G G   A  + +G+  +
Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283

Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170
           ++ +++      G       YGG    YG     +QQ      G G     + S    G 
Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200
             GG     GQ+Q                   M S GGS   Y +           Q Q+
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223
              G+   GQQ   G G G   G
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%)

Query: 4    NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61
            N  T  A    G + P   G+   + +  P+G  +   G S+   T G   +S      +
Sbjct: 1234 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1293

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120
            Q+      +   G      YG+S   +   YGQQ  YPG G               S   
Sbjct: 1294 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1338

Query: 121  SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170
             YG  Q G Y QQP+Y       YG      +   YN      QQ  YN   G   G
Sbjct: 1339 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1395



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410
           GGG G GG G GG  G GG G G            +GGGG GG+                
Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316

Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437
                  P GGG             GG Q+ AG  + P+     +N
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 49/206 (23%), Positives = 61/206 (29%), Gaps = 19/206 (9%)

Query: 10  ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60
           A  + G +    GQ      + P   Q  +  S    + G     YSS           Q
Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396

Query: 61  SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113
           SQ    G  +  Q   +  G G    +Q +         QQ S+P         +   S 
Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456

Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           GS        +PQ       P    QQ S     SY PP   G Q       G   G   
Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513

Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQ 199
           G  Y Q Q     G     GY  Q Q
Sbjct: 514 GMQYPQQQMPPQYGQQGVSGYCQQGQ 539



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 42/169 (24%), Positives = 54/169 (31%), Gaps = 38/169 (22%)

Query: 18  PTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST------ 71
           P+QP    +   +   GQQ+ +G     D      ++  ++  +Q   +   S       
Sbjct: 392 PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT 451

Query: 72  ----------------PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG---- 111
                           PQ YG  G    SQ  QSS     SY   G Q  P    G    
Sbjct: 452 MGRSQGSPMDPMVMKRPQLYGM-GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510

Query: 112 -----SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQS--YNPPQ 153
                 Y        YGQ     Y QQ    GQQ  Y QQ    + PPQ
Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGYCQQ----GQQPYYSQQPQPPHLPPQ 555



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%)

Query: 22  GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76
           GQG SQ   + P G+   +G             + SS G SQ  G G      +  +   
Sbjct: 813 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135
                    ++ S+  +Q S+PG  Q    +S+S      + SSS    Q+  YS  P+
Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 931



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%)

Query: 25   YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80
            YS Q  + Y Q   S YS        GQ  Y  Y + +  G G   T    PQ  G    
Sbjct: 1378 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1431

Query: 81   YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129
             G  QSS S   QQ+ +      P P       G  +Q+  Y              +   
Sbjct: 1432 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1490

Query: 130  YSQQPSYGGQQQSY-----GQQQSYNPPQ 153
             SQ PS+  Q+Q Y       Q    PPQ
Sbjct: 1491 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1519


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 23  QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74
           Q   QQ  Q   QQ     S +    G G  +           +G ++++  G Q+ P G
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117

Query: 75  YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114
                  G    +    G+ +     +PG G    QQP  +   G             YG
Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177

Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156
           S++ +S     ++G    Q  +GGQQ             + G   S +P Q    GY   
Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235

Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213
           Q N Y   S    GGGGGGGGG           GGGSGGG G     GG G+GG G    
Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281

Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259
                  +   GGGGGGGY  SS GY     PR +GGG   G GG G         GS  
Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341

Query: 260 GGFNKFGGPRDQGS 273
           GGF +F G     S
Sbjct: 342 GGFQRFAGQNQHPS 355



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435
           N   G  R G G GG  G GG GGGGSGGGG GG    GG G G   A            
Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284

Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495
                        A    G GGG GGS  G       R   GG   G     GG      
Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333

Query: 496 GGRGGGDRGGF 506
               G   GGF
Sbjct: 334 KAAAGSAAGGF 344



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%)

Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419
           ++R G  G GG G GG  G GG GGGG  G G  G              +GGGGGGG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%)

Query: 26  SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85
           SQ   QP G QS        ++S +   S S   Q +    GTQ  PQ            
Sbjct: 691 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 730

Query: 86  SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145
              + YG Q + P     P+P     +  SS Q S+     SG+Y      G Q   YG 
Sbjct: 731 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 778

Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199
           Q +Y+ P  Y      + S  G G G    N  +GQ  S    ++  G     G  N+  
Sbjct: 779 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 838

Query: 200 SGGGGS---GGYGQQDRGGRGRG 219
            G   S      G   +GG G G
Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMG 861



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%)

Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438
           G      GGP GR G      GG    G G   S      G   + D        +N + 
Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230

Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494
            + N +CN        G GGG GG   GG       GG GG   GG  G GG   G    
Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283

Query: 495 --------RGGRGGGDRGGFGPG 509
                    GG GGG  GG   G
Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 81/313 (25%), Positives = 92/313 (29%), Gaps = 80/313 (25%)

Query: 1   MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPY-----------------GQQSYSGYSQ 43
           MA   Y QQ  Q    Y  Q   GY QQ  QPY                   QS   Y  
Sbjct: 512 MAGMQYPQQ--QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP 569

Query: 44  STDTS--GYGQSSYSSY-------------------------GQSQNTGYGTQSTPQGYG 76
             D S  GYG  S                             G   +   GT++T     
Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629

Query: 77  STGGYGSSQSSQSSYGQQ----------SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126
           S  G  SSQ  QS+  Q           SS PG    P+PS      GS+   S    P 
Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPA 686

Query: 127 SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS--- 183
           S   SQ P      QS   + S +P        Q      G         YG  Q+    
Sbjct: 687 SIPGSQMPPQPPGSQS---ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743

Query: 184 ---MSSGGGSGGGYGNQDQSGGGGSGG-----YGQQDRGGRGRGGSG-------GGGGGG 228
               S GG    G  +  QS   G+ G     YG Q    R    SG       G G G 
Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803

Query: 229 GGGYNRSSGGYEP 241
           G   N    G  P
Sbjct: 804 GISANNQMHGQGP 816



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%)

Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191
           QQ +   QQQ   QQQ     Q   QQ+  ++++  GG GGG    G D      GG   
Sbjct: 50  QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106

Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226
              G Q    G                 G    G+ +  G G  G+         GGGG 
Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166

Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
                +N   G   P    GG GGR G      GG
Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%)

Query: 21  PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78
           PG G    +   +     S    S    G     +  +G  Q+ G G    ++    G+ 
Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219

Query: 79  GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124
           G     Q+S   Y   Q + YPGY +  A     G  G    S   G             
Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279

Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179
               + + +   + GG    YG   +     GYG  +      GG   G GGGG  +  +
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334

Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201
             +  ++GG       NQ  SG
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%)

Query: 4   NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55
           N+Y   A  + G    + G  + Q   Q   Q    G   S   +  G        Q+S+
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229

Query: 56  SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115
             Y  SQ   Y   S P   G  GG G         G      G G   A  + +G+  +
Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283

Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170
           ++ +++      G       YGG    YG     +QQ      G G     + S    G 
Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200
             GG     GQ+Q                   M S GGS   Y +           Q Q+
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223
              G+   GQQ   G G G   G
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%)

Query: 4    NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61
            N  T  A    G + P   G+   + +  P+G  +   G S+   T G   +S      +
Sbjct: 1181 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1240

Query: 62   QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120
            Q+      +   G      YG+S   +   YGQQ  YPG G               S   
Sbjct: 1241 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1285

Query: 121  SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170
             YG  Q G Y QQP+Y       YG      +   YN      QQ  YN   G   G
Sbjct: 1286 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1342



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%)

Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410
           GGG G GG G GG  G GG G G            +GGGG GG+                
Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316

Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437
                  P GGG             GG Q+ AG  + P+     +N
Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 49/206 (23%), Positives = 61/206 (29%), Gaps = 19/206 (9%)

Query: 10  ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60
           A  + G +    GQ      + P   Q  +  S    + G     YSS           Q
Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396

Query: 61  SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113
           SQ    G  +  Q   +  G G    +Q +         QQ S+P         +   S 
Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456

Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
           GS        +PQ       P    QQ S     SY PP   G Q       G   G   
Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513

Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQ 199
           G  Y Q Q     G     GY  Q Q
Sbjct: 514 GMQYPQQQMPPQYGQQGVSGYCQQGQ 539



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 42/169 (24%), Positives = 54/169 (31%), Gaps = 38/169 (22%)

Query: 18  PTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST------ 71
           P+QP    +   +   GQQ+ +G     D      ++  ++  +Q   +   S       
Sbjct: 392 PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT 451

Query: 72  ----------------PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG---- 111
                           PQ YG  G    SQ  QSS     SY   G Q  P    G    
Sbjct: 452 MGRSQGSPMDPMVMKRPQLYGM-GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510

Query: 112 -----SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQS--YNPPQ 153
                 Y        YGQ     Y QQ    GQQ  Y QQ    + PPQ
Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGYCQQ----GQQPYYSQQPQPPHLPPQ 555



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%)

Query: 22  GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76
           GQG SQ   + P G+   +G             + SS G SQ  G G      +  +   
Sbjct: 813 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135
                    ++ S+  +Q S+PG  Q    +S+S      + SSS    Q+  YS  P+
Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 931



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%)

Query: 25   YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80
            YS Q  + Y Q   S YS        GQ  Y  Y + +  G G   T    PQ  G    
Sbjct: 1325 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1378

Query: 81   YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129
             G  QSS S   QQ+ +      P P       G  +Q+  Y              +   
Sbjct: 1379 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1437

Query: 130  YSQQPSYGGQQQSY-----GQQQSYNPPQ 153
             SQ PS+  Q+Q Y       Q    PPQ
Sbjct: 1438 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1466


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 67/198 (33%), Positives = 83/198 (41%), Gaps = 26/198 (13%)

Query: 77  STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126
           ++GG+G   S     GQ    PG    P     P +++GS+G + Q + +GQ      P 
Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203

Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182
            G+ +Q    QP YG  + S   +   NPP          S SGGG    GGG+  Q   
Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251

Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242
           S SSG GS G   N   SGG  SG       GG   G SG  GG  G   + SS G    
Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311

Query: 243 GRGGGRGGRGGMGGSDRG 260
              G  GG GG  G   G
Sbjct: 312 SSSGNHGGSGGGNGHKPG 329



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 73/246 (29%), Positives = 87/246 (35%), Gaps = 39/246 (15%)

Query: 15  GAYPTQPGQGYSQQSSQPYGQ-QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ 73
           GA+ T  G G         GQ Q   G   +    GY  +S  S+G +       Q  P 
Sbjct: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP------QGAPW 193

Query: 74  GYGSTGGYGS-SQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132
           G G  GG  +   ++Q +  Q    PGYG   A +   G        S  G   SG  S 
Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQ----PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249

Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192
             S      S G   + +   G        SSSG   GG             SSGG SGG
Sbjct: 250 SQSGSSGSGSNGDNNNGSSSGG--------SSSGSSSGG-------------SSGGSSGG 288

Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP--RGRGGGRGG 250
             GN     GG  G  G +   G   G S G  GG GGG     G  +P    RG G  G
Sbjct: 289 SSGN----SGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344

Query: 251 RGGMGG 256
             G  G
Sbjct: 345 IQGFRG 350



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 69/284 (24%), Positives = 92/284 (32%), Gaps = 51/284 (17%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQST-DTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGG 80
           G+   +++    G +      Q T +  G G      +G +   G          G+TG 
Sbjct: 52  GKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111

Query: 81  YGSSQS-------SQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133
               Q+       + +  G     PG+      S   G +GS       GQ   G     
Sbjct: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTP 171

Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS----------- 182
             +G    S G          +G   Q   +  G GG GG  N+G +             
Sbjct: 172 WVHGYPGNSAGS---------FGMNPQ--GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220

Query: 183 --------------SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRG-----GSGG 223
                         S S GG S  G G+  QSG  GSG  G  + G    G      SGG
Sbjct: 221 RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280

Query: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267
             GG  GG + +SGG   RG  G     G   GS  G     GG
Sbjct: 281 SSGGSSGGSSGNSGG--SRGDSGSESSWGSSTGSSSGNHGGSGG 322



 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%)

Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427
           G   G GG+G+G P G G     GY G  +G  G    G P G GG GG    G      
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211

Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485
              P   ++  S +NE   C  P P G GGG    G   G   G    G  G  + G   
Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269

Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516
           G    G   GG  GG  GG  G  G  + DS  E
Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 65/278 (23%), Positives = 95/278 (34%), Gaps = 39/278 (14%)

Query: 43  QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98
           +ST T+  G++     G + + G G     +  G+ G   S    Q ++ + G      P
Sbjct: 29  ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87

Query: 99  GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145
           G+G   A  +  G    +  ++ +                  GS+   P + G  ++ G 
Sbjct: 88  GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147

Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198
              +    G G Q Q N    G     G  G   G++G +      G G  GG  N   +
Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207

Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGGGGGGGGYNRSSG-------GYEPRGR 244
             G     GYG      +  G       GSGGG    GGG    SG       G    G 
Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267

Query: 245 GGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282
             G    G   G   GG +        GSR DS  ++S
Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%)

Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211
           G+G  +  +   G   G   GG  G   S ++  G     G G +   G G +   G + 
Sbjct: 40  GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99

Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256
                  G +G   G               G   G    +G +E  G  G  G +GG+GG
Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159

Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316
             +G     G P   G   +S      N      G G N    +            TN +
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209

Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376
                    + R + + +G      + PPS         G   SG               
Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247

Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
            G  +G  G G  G    G   GG S G   GG  SGG  GG    +G  +  +      
Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302

Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
             SW +           G   G  G   GGN      G + G ++ G   RG    G +G
Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347

Query: 497 GRGGG 501
            RG G
Sbjct: 348 FRGQG 352



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%)

Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414
           GN  G  G   +G P G+GG GG  + G    G                       PSG 
Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237

Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468
           GGG      G       +    N    N  +   +      GG  GGS      + GG+ 
Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297

Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505
           GD       G   G   G  G  GG  G + G ++ G
Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 29/183 (15%)

Query: 11  TQSYGAYPTQPGQGYSQQSSQPYG----QQSYSGYSQSTDTSGYG-QSSYSSYGQSQNTG 65
           T + GA   QPG G  + S+Q  G      S SG   S    G G QS  S  G + +  
Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264

Query: 66  YGTQSTPQGYGST-GGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ 124
            G+ S     GS+ GG     S  SS                 ++ GS G S   SS+G 
Sbjct: 265 NGSSSGGSSSGSSSGGSSGGSSGGSS----------------GNSGGSRGDSGSESSWG- 307

Query: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184
             S + S   ++GG     G +     P   G + + +  SG  G  G G +     S  
Sbjct: 308 --SSTGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMRNSET 362

Query: 185 SSG 187
           S G
Sbjct: 363 SPG 365


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 76/240 (31%), Positives = 103/240 (42%), Gaps = 52/240 (21%)

Query: 287 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD-PP 345
           +FV G+ E+     + DYF++ G I T        I + TDR++GK +G   V+FDD  P
Sbjct: 114 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 165

Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGR-GRGGPMGRGGYGGGGS 402
             K  +  +     +G+  +V  A  R +    +   +GRGG  G G   G GG  G G 
Sbjct: 166 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGP 223

Query: 403 GG---GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459
           G    GG  G+ SG G G G                                 +G GGGP
Sbjct: 224 GSNFRGGSDGYGSGRGFGDGY--------------------------------NGYGGGP 251

Query: 460 GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQ 519
           GG + GG+ G    GGRGGY  GG  G G   GG+ GG      G +G G  +  G + Q
Sbjct: 252 GGGNFGGSPG--YGGGRGGYGGGG-PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQ 308



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 53/130 (40%), Positives = 61/130 (46%), Gaps = 21/130 (16%)

Query: 157 QQNQYNSSSGGGGGG-----GGGGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGG 207
           Q+ Q + S  GG  G     GGGGN+G    S   GG    GSG G+G+     GGG GG
Sbjct: 194 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG 253

Query: 208 --YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265
             +G    G  G GG  GG GGGG GY    GGY     GGG    GG G    G +N F
Sbjct: 254 GNFG----GSPGYGGGRGGYGGGGPGYGNQGGGY-----GGGYDNYGG-GNYGSGNYNDF 303

Query: 266 GGPRDQGSRH 275
           G    Q S +
Sbjct: 304 GNYNQQPSNY 313



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 58/173 (33%), Positives = 69/173 (39%), Gaps = 25/173 (14%)

Query: 103 QPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYN 162
           Q   SS SG  G+      +G  + G  +  P  G   +  G    Y   +G+G  + YN
Sbjct: 194 QEVQSSRSGRGGNFG----FGDSRGGGGNFGPGPGSNFR--GGSDGYGSGRGFG--DGYN 245

Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222
              GG GGG  GG+ G        GGG G GYGNQ   GGG  GGY        G G  G
Sbjct: 246 GYGGGPGGGNFGGSPGYGGGRGGYGGG-GPGYGNQ---GGGYGGGYDNY-----GGGNYG 296

Query: 223 GGGGGGGGGYNRSSGGYEPRGRG--------GGRGGRGGMGGSDRGGFNKFGG 267
            G     G YN+    Y P   G        GG  G G  G    GG   +GG
Sbjct: 297 SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 55/161 (34%), Positives = 62/161 (38%), Gaps = 18/161 (11%)

Query: 118 QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
           QSS  G+  +  +      GG               GYG    +     G GGG GGGN+
Sbjct: 197 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNF 256

Query: 178 GQDQSSMSSGGGSGG------GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231
           G    S   GGG GG      GYGNQ   GGG  GGY        G G  G G     G 
Sbjct: 257 G---GSPGYGGGRGGYGGGGPGYGNQ---GGGYGGGYDNY-----GGGNYGSGNYNDFGN 305

Query: 232 YNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272
           YN+    Y P  + G  GG   MGG   GG    GG    G
Sbjct: 306 YNQQPSNYGPM-KSGNFGGSRNMGGPYGGGNYGPGGSGGSG 345



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 46/115 (40%), Positives = 54/115 (46%), Gaps = 18/115 (15%)

Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGR 216
           +  +  SS  G GG  G G+      S   GG  G G G+  +   GGS GYG     G 
Sbjct: 192 EMQEVQSSRSGRGGNFGFGD------SRGGGGNFGPGPGSNFR---GGSDGYGSGRGFGD 242

Query: 217 GRGGSGGGGGGG--GG--GYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267
           G  G GGG GGG  GG  GY    GGY     GGG  G G  GG   GG++ +GG
Sbjct: 243 GYNGYGGGPGGGNFGGSPGYGGGRGGY-----GGGGPGYGNQGGGYGGGYDNYGG 292



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 66/200 (33%), Positives = 79/200 (39%), Gaps = 53/200 (26%)

Query: 69  QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128
           QS+  G G   G+G S+    ++G     PG    P  +   GS G  S    +G   +G
Sbjct: 197 QSSRSGRGGNFGFGDSRGGGGNFG-----PG----PGSNFRGGSDGYGS-GRGFGDGYNG 246

Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
            Y   P  G    ++G    Y                GGG GG GGG  G      + GG
Sbjct: 247 -YGGGPGGG----NFGGSPGY----------------GGGRGGYGGGGPGYG----NQGG 281

Query: 189 GSGGGYGNQDQSGGG--GSGGYG-------QQDRGGRGRGGSGGGGGGGGGGYNRSSGGY 239
           G GGGY   D  GGG  GSG Y        Q    G  + G+ GG    GG Y    G Y
Sbjct: 282 GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY--GGGNY 336

Query: 240 EPRGRGGGRGGRGGMGGSDR 259
            P    GG GG GG GG  R
Sbjct: 337 GP----GGSGGSGGYGGRSR 352



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 51/171 (29%), Positives = 65/171 (38%), Gaps = 26/171 (15%)

Query: 43  QSTDTSGYGQSSYSSYGQSQNTG--YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100
           Q   +S  G+     +G S+  G  +G        G + GYGS +      G    Y GY
Sbjct: 194 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGR------GFGDGYNGY 247

Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ----SYNPPQGYG 156
           G  P   +  GS G       YG    G  +Q   YGG   +YG       +YN    Y 
Sbjct: 248 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYN 307

Query: 157 QQ-NQYNSSSGGGGGGG-------GGGNYGQDQSSMSSGGGSGGGYGNQDQ 199
           QQ + Y     G  GG        GGGNYG        G G  GGYG + +
Sbjct: 308 QQPSNYGPMKSGNFGGSRNMGGPYGGGNYG------PGGSGGSGGYGGRSR 352



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 51/162 (31%), Positives = 63/162 (38%), Gaps = 22/162 (13%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81
           G G S+     +G    S +   +D  GYG  S   +G   N GYG       +G + GY
Sbjct: 208 GFGDSRGGGGNFGPGPGSNFRGGSD--GYG--SGRGFGDGYN-GYGGGPGGGNFGGSPGY 262

Query: 82  GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYS------QQPS 135
           G  +      G     PGYG Q       G YG    +   G   SG+Y+      QQPS
Sbjct: 263 GGGRGGYGGGG-----PGYGNQ------GGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 311

Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
             G  +S     S N    YG  N     SGG GG GG   Y
Sbjct: 312 NYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 353



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 20/31 (64%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 380 GNGRGGRGRGGPMGRGGYGGGGSGG-GGRGG 409
           GN  G R  GGP G G YG GGSGG GG GG
Sbjct: 319 GNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 15/30 (50%), Positives = 15/30 (50%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405
           N GG    GG   GG  G GG GG G  GG
Sbjct: 320 NFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 76/240 (31%), Positives = 103/240 (42%), Gaps = 52/240 (21%)

Query: 287 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD-PP 345
           +FV G+ E+     + DYF++ G I T        I + TDR++GK +G   V+FDD  P
Sbjct: 102 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 153

Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGR-GRGGPMGRGGYGGGGS 402
             K  +  +     +G+  +V  A  R +    +   +GRGG  G G   G GG  G G 
Sbjct: 154 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGP 211

Query: 403 GG---GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459
           G    GG  G+ SG G G G                                 +G GGGP
Sbjct: 212 GSNFRGGSDGYGSGRGFGDGY--------------------------------NGYGGGP 239

Query: 460 GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQ 519
           GG + GG+ G    GGRGGY  GG  G G   GG+ GG      G +G G  +  G + Q
Sbjct: 240 GGGNFGGSPG--YGGGRGGYGGGG-PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQ 296



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 53/130 (40%), Positives = 61/130 (46%), Gaps = 21/130 (16%)

Query: 157 QQNQYNSSSGGGGGG-----GGGGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGG 207
           Q+ Q + S  GG  G     GGGGN+G    S   GG    GSG G+G+     GGG GG
Sbjct: 182 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG 241

Query: 208 --YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265
             +G    G  G GG  GG GGGG GY    GGY     GGG    GG G    G +N F
Sbjct: 242 GNFG----GSPGYGGGRGGYGGGGPGYGNQGGGY-----GGGYDNYGG-GNYGSGNYNDF 291

Query: 266 GGPRDQGSRH 275
           G    Q S +
Sbjct: 292 GNYNQQPSNY 301



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 58/173 (33%), Positives = 69/173 (39%), Gaps = 25/173 (14%)

Query: 103 QPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYN 162
           Q   SS SG  G+      +G  + G  +  P  G   +  G    Y   +G+G  + YN
Sbjct: 182 QEVQSSRSGRGGNFG----FGDSRGGGGNFGPGPGSNFR--GGSDGYGSGRGFG--DGYN 233

Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222
              GG GGG  GG+ G        GGG G GYGNQ   GGG  GGY        G G  G
Sbjct: 234 GYGGGPGGGNFGGSPGYGGGRGGYGGG-GPGYGNQ---GGGYGGGYDNY-----GGGNYG 284

Query: 223 GGGGGGGGGYNRSSGGYEPRGRG--------GGRGGRGGMGGSDRGGFNKFGG 267
            G     G YN+    Y P   G        GG  G G  G    GG   +GG
Sbjct: 285 SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 55/161 (34%), Positives = 62/161 (38%), Gaps = 18/161 (11%)

Query: 118 QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
           QSS  G+  +  +      GG               GYG    +     G GGG GGGN+
Sbjct: 185 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNF 244

Query: 178 GQDQSSMSSGGGSGG------GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231
           G    S   GGG GG      GYGNQ   GGG  GGY        G G  G G     G 
Sbjct: 245 G---GSPGYGGGRGGYGGGGPGYGNQ---GGGYGGGYDNY-----GGGNYGSGNYNDFGN 293

Query: 232 YNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272
           YN+    Y P  + G  GG   MGG   GG    GG    G
Sbjct: 294 YNQQPSNYGPM-KSGNFGGSRNMGGPYGGGNYGPGGSGGSG 333



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 46/115 (40%), Positives = 54/115 (46%), Gaps = 18/115 (15%)

Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGR 216
           +  +  SS  G GG  G G+      S   GG  G G G+  +   GGS GYG     G 
Sbjct: 180 EMQEVQSSRSGRGGNFGFGD------SRGGGGNFGPGPGSNFR---GGSDGYGSGRGFGD 230

Query: 217 GRGGSGGGGGGG--GG--GYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267
           G  G GGG GGG  GG  GY    GGY     GGG  G G  GG   GG++ +GG
Sbjct: 231 GYNGYGGGPGGGNFGGSPGYGGGRGGY-----GGGGPGYGNQGGGYGGGYDNYGG 280



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 66/200 (33%), Positives = 79/200 (39%), Gaps = 53/200 (26%)

Query: 69  QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128
           QS+  G G   G+G S+    ++G     PG    P  +   GS G  S    +G   +G
Sbjct: 185 QSSRSGRGGNFGFGDSRGGGGNFG-----PG----PGSNFRGGSDGYGS-GRGFGDGYNG 234

Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
            Y   P  G    ++G    Y                GGG GG GGG  G      + GG
Sbjct: 235 -YGGGPGGG----NFGGSPGY----------------GGGRGGYGGGGPGYG----NQGG 269

Query: 189 GSGGGYGNQDQSGGG--GSGGYG-------QQDRGGRGRGGSGGGGGGGGGGYNRSSGGY 239
           G GGGY   D  GGG  GSG Y        Q    G  + G+ GG    GG Y    G Y
Sbjct: 270 GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY--GGGNY 324

Query: 240 EPRGRGGGRGGRGGMGGSDR 259
            P    GG GG GG GG  R
Sbjct: 325 GP----GGSGGSGGYGGRSR 340



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 51/171 (29%), Positives = 65/171 (38%), Gaps = 26/171 (15%)

Query: 43  QSTDTSGYGQSSYSSYGQSQNTG--YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100
           Q   +S  G+     +G S+  G  +G        G + GYGS +      G    Y GY
Sbjct: 182 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGR------GFGDGYNGY 235

Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ----SYNPPQGYG 156
           G  P   +  GS G       YG    G  +Q   YGG   +YG       +YN    Y 
Sbjct: 236 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYN 295

Query: 157 QQ-NQYNSSSGGGGGGG-------GGGNYGQDQSSMSSGGGSGGGYGNQDQ 199
           QQ + Y     G  GG        GGGNYG        G G  GGYG + +
Sbjct: 296 QQPSNYGPMKSGNFGGSRNMGGPYGGGNYG------PGGSGGSGGYGGRSR 340



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 51/162 (31%), Positives = 63/162 (38%), Gaps = 22/162 (13%)

Query: 22  GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81
           G G S+     +G    S +   +D  GYG  S   +G   N GYG       +G + GY
Sbjct: 196 GFGDSRGGGGNFGPGPGSNFRGGSD--GYG--SGRGFGDGYN-GYGGGPGGGNFGGSPGY 250

Query: 82  GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYS------QQPS 135
           G  +      G     PGYG Q       G YG    +   G   SG+Y+      QQPS
Sbjct: 251 GGGRGGYGGGG-----PGYGNQ------GGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 299

Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
             G  +S     S N    YG  N     SGG GG GG   Y
Sbjct: 300 NYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 341



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 20/31 (64%), Positives = 20/31 (64%), Gaps = 1/31 (3%)

Query: 380 GNGRGGRGRGGPMGRGGYGGGGSGG-GGRGG 409
           GN  G R  GGP G G YG GGSGG GG GG
Sbjct: 307 GNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 15/30 (50%), Positives = 15/30 (50%)

Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405
           N GG    GG   GG  G GG GG G  GG
Sbjct: 308 NFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.135    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,911,207
Number of Sequences: 37866
Number of extensions: 2186574
Number of successful extensions: 76870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 910
Number of HSP's successfully gapped in prelim test: 752
Number of HSP's that attempted gapping in prelim test: 12634
Number of HSP's gapped (non-prelim): 22568
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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