BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] (526 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 1128 0.0 gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 464 e-130 gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 459 e-129 gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 458 e-129 gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 457 e-129 gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 407 e-113 gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 404 e-112 gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 152 7e-37 gi|62122917 filaggrin family member 2 [Homo sapiens] 148 1e-35 gi|57864582 hornerin [Homo sapiens] 139 6e-33 gi|55956899 keratin 9 [Homo sapiens] 101 1e-21 gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 101 2e-21 gi|55956788 nucleolin [Homo sapiens] 98 2e-20 gi|195972866 keratin 10 [Homo sapiens] 97 5e-20 gi|109255251 loricrin [Homo sapiens] 97 5e-20 gi|119395750 keratin 1 [Homo sapiens] 95 1e-19 gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 94 3e-19 gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 94 3e-19 gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 94 4e-19 gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 93 7e-19 gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 92 9e-19 gi|109452587 family with sequence similarity 98, member B isofor... 92 1e-18 gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 91 2e-18 gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 91 2e-18 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 91 2e-18 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 91 2e-18 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 91 2e-18 gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 91 3e-18 gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 90 6e-18 gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 90 6e-18 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 1128 bits (2917), Expect = 0.0 Identities = 526/526 (100%), Positives = 526/526 (100%) Query: 1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ Sbjct: 1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60 Query: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS Sbjct: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 Query: 121 SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD 180 SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD Sbjct: 121 SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD 180 Query: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE 240 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE Sbjct: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE 240 Query: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES 300 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES Sbjct: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES 300 Query: 301 VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS 360 VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS Sbjct: 301 VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS 360 Query: 361 GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420 GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ Sbjct: 361 GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420 Query: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD Sbjct: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480 Query: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY Sbjct: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526 >gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo sapiens] Length = 600 Score = 464 bits (1193), Expect = e-130 Identities = 298/623 (47%), Positives = 360/623 (57%), Gaps = 120/623 (19%) Query: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48 MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+ Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59 Query: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91 YGQ++Y+ SYGQ TGY T + PQ Y TG Y + S ++QS+Y Sbjct: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118 Query: 92 GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151 G Q +YP YGQQPA ++ + SY SS+Q +SY Q SYSQQ +YG Q SYGQQ SY Sbjct: 119 GTQPAYPAYGQQPAATAPT-SY-SSTQPTSYDQ---SSYSQQNTYG-QPSSYGQQSSYGQ 172 Query: 152 PQGYGQQ--NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYG 209 YGQQ Y +G +Y Q S S S G + Q G YG Sbjct: 173 QSSYGQQPPTSYPPQTG---------SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG 223 Query: 210 QQDRG----GRGRGGSGGGGGGGG-GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK 264 Q+ G G R SG G G GG++R GG GRGGGRGG G G +RGGFNK Sbjct: 224 QESGGFSGPGENRSMSGPDNRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNK 279 Query: 265 FGGPRDQGSRHD-----SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQ 319 GGP D+G D ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQ Sbjct: 280 PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ 339 Query: 320 PMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--R 377 PMI++Y D+ETGK KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N R Sbjct: 340 PMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMR 399 Query: 378 GGGNGRGGRG-----RGGPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGG 419 GG R GRG RGGP G GG GG G GG RGGFP G GGG Sbjct: 400 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 459 Query: 420 QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG- 465 Q RAGDW+CPNP C N NF+WR ECNQCKAPKP+G PG GGPGG G Sbjct: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519 Query: 466 ------GNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RG 504 G G RGGRGG DRGG+R GRG DRGGF GGR GG RG Sbjct: 520 GGLMDRGGPGGMFRGGRGG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRG 578 Query: 505 G-FGPGKMDSRGEHRQDRRERPY 526 G GPGKMD +GEHRQ+RR+RPY Sbjct: 579 GRGGPGKMD-KGEHRQERRDRPY 600 >gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo sapiens] Length = 655 Score = 459 bits (1180), Expect = e-129 Identities = 297/661 (44%), Positives = 358/661 (54%), Gaps = 141/661 (21%) Query: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48 MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+ Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59 Query: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91 YGQ++Y+ SYGQ TGY T + PQ Y TG Y + S ++QS+Y Sbjct: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118 Query: 92 GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129 G Q +YP YGQQPA P S++G Y S S+Y PQ GS Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178 Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 Y QP SY Q SY QQ +Y P YGQQ+ Y S G Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238 Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 G+Y Q S S S G + Q G YGQ+ G G G + G Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPD 298 Query: 229 GGGYNRSSGGYEPRG--RGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD-----SEQDN 281 G R GG++ G RGG GGRGGMG +RGGFNK GGP D+G D ++ Sbjct: 299 NRG--RGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 356 Query: 282 SDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSF 341 SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+ATVS+ Sbjct: 357 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 416 Query: 342 DDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RGGPMGR 394 +DPP+AKAA++WFDGK+F G+ +KVS A ++ N RGG R GRG RGGP G Sbjct: 417 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 476 Query: 395 GGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENMNFSWR 441 GG GG G GG RGGFP G GGG Q RAGDW+CPNP C N NF+WR Sbjct: 477 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 536 Query: 442 NECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGRGGYDR 481 ECNQCKAPKP+G PG GGPGG G G G RGGRGG DR Sbjct: 537 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG-DR 595 Query: 482 GGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQDRRERP 525 GG+R GRG DRGGF GGR GG RGG GPGKMD +GEHRQ+RR+RP Sbjct: 596 GGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERRDRP 654 Query: 526 Y 526 Y Sbjct: 655 Y 655 >gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo sapiens] Length = 661 Score = 458 bits (1178), Expect = e-129 Identities = 297/666 (44%), Positives = 359/666 (53%), Gaps = 145/666 (21%) Query: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48 MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+ Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59 Query: 49 GYGQSSYS-SYGQ-----SQNTGYGTQSTPQGYGS------TGGYGS----------SQS 86 YGQ++Y+ SYGQ +TGY T + PQ Y TG Y + S + Sbjct: 60 TYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYA 119 Query: 87 SQSSYGQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQP 125 +QS+YG Q +YP YGQQPA P S++G Y S S+Y P Sbjct: 120 AQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYP 179 Query: 126 Q-SGSYSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168 Q GSY QP SY Q SY QQ +Y P YGQQ+ Y S G Sbjct: 180 QVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 239 Query: 169 GGGGGG-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGG 223 G+Y Q S S S G + Q G YGQ+ G G G + Sbjct: 240 QQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRS 299 Query: 224 GGGGGGGGYNRSSGGYEPRG--RGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD----- 276 G G R GG++ G RGG GGRGGMG +RGGFNK GGP D+G D Sbjct: 300 MSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPV 357 Query: 277 SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGE 336 ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+ Sbjct: 358 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 417 Query: 337 ATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RG 389 ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N RGG R GRG RG Sbjct: 418 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 477 Query: 390 GPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENM 436 GP G GG GG G GG RGGFP G GGG Q RAGDW+CPNP C N Sbjct: 478 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 537 Query: 437 NFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGR 476 NF+WR ECNQCKAPKP+G PG GGPGG G G G RGGR Sbjct: 538 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 597 Query: 477 GGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQD 520 GG DRGG+R GRG DRGGF GGR GG RGG GPGKMD +GEHRQ+ Sbjct: 598 GG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQE 655 Query: 521 RRERPY 526 RR+RPY Sbjct: 656 RRDRPY 661 >gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sapiens] Length = 656 Score = 457 bits (1177), Expect = e-129 Identities = 300/664 (45%), Positives = 360/664 (54%), Gaps = 146/664 (21%) Query: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48 MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+ Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59 Query: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91 YGQ++Y+ SYGQ TGY T + PQ Y TG Y + S ++QS+Y Sbjct: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118 Query: 92 GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129 G Q +YP YGQQPA P S++G Y S S+Y PQ GS Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178 Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 Y QP SY Q SY QQ +Y P YGQQ+ Y S G Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238 Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG----GRGRGGSGGG 224 G+Y Q S S S G + Q G YGQ+ G G R SG Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPD 298 Query: 225 GGGGG-GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD-----SE 278 G G GG++R GG GRGGGRGG G G +RGGFNK GGP D+G D Sbjct: 299 NRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNKPGGPMDEGPDLDLGPPVDP 354 Query: 279 QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 338 ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+AT Sbjct: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414 Query: 339 VSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RGGP 391 VS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N RGG R GRG RGGP Sbjct: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474 Query: 392 MGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENMNF 438 G GG GG G GG RGGFP G GGG Q RAGDW+CPNP C N NF Sbjct: 475 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534 Query: 439 SWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGRGG 478 +WR ECNQCKAPKP+G PG GGPGG G G G RGGRGG Sbjct: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594 Query: 479 YDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQDRR 522 DRGG+R GRG DRGGF GGR GG RGG GPGKMD +GEHRQ+RR Sbjct: 595 -DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERR 652 Query: 523 ERPY 526 +RPY Sbjct: 653 DRPY 656 >gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] Length = 592 Score = 407 bits (1046), Expect = e-113 Identities = 267/522 (51%), Positives = 299/522 (57%), Gaps = 89/522 (17%) Query: 12 QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69 QSY Y QGY Q S QSYSGY Q+TD+S YGQ S YSSYGQSQ +GY Sbjct: 15 QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSQ-SGYS-- 64 Query: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129 Q YG G QSSY QQ Y GQQ S SGS G ++ SY QP G Sbjct: 65 ---QSYG-----GYENQKQSSYSQQP-YNNQGQQQNMES-SGSQGG--RAPSYDQPDYG- 111 Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188 QQ SY QQ Y+ QG Y +Q+ Y+ +Y Q+Q S S Sbjct: 112 ---------QQDSYDQQSGYDQHQGSYDEQSNYDQQHD---------SYSQNQQSYHS-- 151 Query: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248 Y + Q YG+ +RG GGS GGG R GGY+ GRG Sbjct: 152 -QRENYSHHTQDDRRDVSRYGEDNRG---YGGSQGGG--------RGRGGYDKDGRGPMT 199 Query: 249 GGRGGMGGSDRGGFNKFGGPRDQGSRHD--SEQDNSDNNTIFVQGLGENVTIESVADYFK 306 G GG DRGGF FGG RD G R D SE DNSDNNTIFVQGLGE V+ + V ++FK Sbjct: 200 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 255 Query: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366 QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV Sbjct: 256 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 315 Query: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426 SFATRR +F RGGG+G G RGRGG GRGG+ GRGG P ++GDW Sbjct: 316 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 358 Query: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483 CPNP+C NMNF+ RN CNQC P+P+ P GG G GG G RGGRGG DRGG Sbjct: 359 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 417 Query: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521 Y G GG GG R GG GDR G G G S G + DR Sbjct: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 459 Score = 111 bits (277), Expect = 2e-24 Identities = 86/224 (38%), Positives = 98/224 (43%), Gaps = 31/224 (13%) Query: 52 QSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG 111 + S S G + GYG + +G G GG + YG S GYG S+ G Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGRGGRGG------DRGGYGGDRSGGGYG---GDRSSGG 435 Query: 112 SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS-YGQQQSYNPPQGYG--QQNQYNSSSGGG 168 Y YG +SG YGG + YG + GYG + Y GG Sbjct: 436 GYSGDRSGGGYGGDRSGG-----GYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGY 486 Query: 169 GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 GG GGG YG D+ GG GGYG GG GGYG G R RGG GG GGG Sbjct: 487 GGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGGG 538 Query: 229 GGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270 G SGGY GGG GG RGG G DRGG+ K GG D Sbjct: 539 SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 582 Score = 106 bits (264), Expect = 6e-23 Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%) Query: 79 GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120 GG G + + Y + + G G P P+ + G+ + ++S Sbjct: 328 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 387 Query: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178 S G + Y + Y G+ G + Y + G SS GG G GG YG Sbjct: 388 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 447 Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236 D+S GG GGGYG G GG GGYG DRGG G G GGG GG GGY Sbjct: 448 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 505 Query: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272 GGY + G GG RGG RGG GG DRGG + +GG R G Sbjct: 506 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 548 Score = 94.7 bits (234), Expect = 2e-19 Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%) Query: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428 +RGGG G RGG G RGG G RGGYGG G GG RGG+ GG GG + G Sbjct: 474 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 529 Query: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488 G GG GG G YG DR GG GG DR G Sbjct: 530 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 555 Query: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526 G GG RGG GGDRGG+G GKM R ++R D+R RPY Sbjct: 556 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 592 Score = 85.9 bits (211), Expect = 8e-17 Identities = 74/205 (36%), Positives = 81/205 (39%), Gaps = 48/205 (23%) Query: 40 GYSQSTDTSGYG--QSSYSSY-GQSQNTGYGTQSTPQGYGST--GGYGSSQSSQSSYGQQ 94 GY GYG +SS Y G GYG + GYG GGYG + Sbjct: 417 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG------- 469 Query: 95 SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154 GYG G YG YG + G YGG + YG Sbjct: 470 ----GYG-----GDRGGGYG--GDRGGYGGDRGG------GYGGDRGGYG---------- 502 Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG 214 G + Y GG GG GG YG D+S GG GGG G GG SGGYG DR Sbjct: 503 -GDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGGSG----YGGDRSGGYG-GDRS 554 Query: 215 GRGRGGSGGGG-GGGGGGYNRSSGG 238 G G GG GGG GG GGY GG Sbjct: 555 GGGYGGDRGGGYGGDRGGYGGKMGG 579 Score = 67.0 bits (162), Expect = 4e-11 Identities = 100/373 (26%), Positives = 133/373 (35%), Gaps = 112/373 (30%) Query: 4 NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58 + Y QQ+ Q G+Y Q Y QQ Y Q S +SQ + S + Q S Y Sbjct: 114 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 170 Query: 59 GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115 G+ N GY G+Q +G G G + SS G + + +G + P + + S Sbjct: 171 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 229 Query: 116 SSQSSSY------------------------------GQPQSGSYSQQPSYGGQQQSYGQ 145 +S +++ G+P Y+ + + G+ + Sbjct: 230 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT--GKPKGEAT 287 Query: 146 QQSYNPPQGYGQQNQYNSSS-------------------GGGGGGG--GGGNYGQDQSSM 184 +PP + ++ GGG GGG G G Y Sbjct: 288 VSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 347 Query: 185 SSGGGSGGG--------YGNQ------------------------DQSGGGGSGGYGQQD 212 GG G GN D G G G G + Sbjct: 348 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 407 Query: 213 RGGRG--RGG-----SGGGGGG---GGGGY--NRSSGGYEPRGRGGGRGG-RGGMGGSDR 259 RGGRG RGG SGGG GG GGGY +RS GGY GGG GG RGG G DR Sbjct: 408 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 467 Query: 260 GGFNKFGGPRDQG 272 GG +GG R G Sbjct: 468 GG--GYGGDRGGG 478 Score = 60.5 bits (145), Expect = 4e-09 Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%) Query: 14 YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72 YG + G G + S Y G +S GY GYG YG + GYG Sbjct: 418 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 477 Query: 73 QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132 G GGYG + GYG G YG YG + G Sbjct: 478 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 518 Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192 + YGG + G GYG GGG GG GG Sbjct: 519 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 564 Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218 GYG GG GG R R Sbjct: 565 GYGGDRGGYGGKMGGRNDYRNDQRNR 590 Score = 55.1 bits (131), Expect = 2e-07 Identities = 91/376 (24%), Positives = 123/376 (32%), Gaps = 110/376 (29%) Query: 4 NDYTQQATQSYGAYPTQPGQG-------------------YSQQSSQPYGQQSY---SGY 41 + Y+QQ + G G Y QQS Q SY S Y Sbjct: 76 SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNY 135 Query: 42 SQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTG----GYGSSQSSQSSYGQQSSY 97 Q D+ Y Q+ S + Q +N + TQ + G GYG SQ G Y Sbjct: 136 DQQHDS--YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRG---GY 190 Query: 98 PGYGQQPAPSSTSGSYG--------------SSSQSSSYGQPQSGSYSQQPSYGGQQQSY 143 G+ P S+ G G + + S S + + Q G Sbjct: 191 DKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQV 250 Query: 144 GQ--QQ----SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS----------- 186 G+ +Q N G N Y G G ++ S+ ++ Sbjct: 251 GEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHG 310 Query: 187 ----------------GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG 230 GGGSGG G + + G G GG+ Q RGG + G G Sbjct: 311 NIIKVSFATRRPEFMRGGGSGG--GRRGRGGYRGRGGF--QGRGGDPKSGDWVCPNPSCG 366 Query: 231 GYN------------------RSSGG-YEPRGRGGGRG--GRGGMGGSDRGGF------N 263 N R SGG + RG GG RG GRGG GG DRGG+ Sbjct: 367 NMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGGYGGDRSGG 425 Query: 264 KFGGPRDQGSRHDSEQ 279 +GG R G + ++ Sbjct: 426 GYGGDRSSGGGYSGDR 441 Score = 38.9 bits (89), Expect = 0.012 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Query: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420 D +RGG G+ GG G GG GGYGG GG GG GG+ GG GG+ Sbjct: 525 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 576 Score = 33.5 bits (75), Expect = 0.49 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409 D + G G R G G GG G GGYGG G GG+ G Sbjct: 544 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 578 >gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] Length = 589 Score = 404 bits (1038), Expect = e-112 Identities = 264/522 (50%), Positives = 298/522 (57%), Gaps = 92/522 (17%) Query: 12 QSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ--SSYSSYGQSQNTGYGTQ 69 QSY Y QGY Q S QSYSGY Q+TD+S YGQ S YSSYGQS + Y Sbjct: 15 QSYSTYGNPGSQGYGQAS------QSYSGYGQTTDSS-YGQNYSGYSSYGQSYSQSY--- 64 Query: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129 GGY + + QSSY QQ Y GQQ S SGS G ++ SY QP G Sbjct: 65 ---------GGYENQK--QSSYSQQP-YNNQGQQQNMES-SGSQGG--RAPSYDQPDYG- 108 Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQG-YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188 QQ SY QQ Y+ QG Y +Q+ Y+ +Y Q+Q S S Sbjct: 109 ---------QQDSYDQQSGYDQHQGSYDEQSNYDQQHD---------SYSQNQQSYHS-- 148 Query: 189 GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGR 248 Y + Q YG+ +RG GGS GGG R GGY+ GRG Sbjct: 149 -QRENYSHHTQDDRRDVSRYGEDNRG---YGGSQGGG--------RGRGGYDKDGRGPMT 196 Query: 249 GGRGGMGGSDRGGFNKFGGPRDQGSRHD--SEQDNSDNNTIFVQGLGENVTIESVADYFK 306 G GG DRGGF FGG RD G R D SE DNSDNNTIFVQGLGE V+ + V ++FK Sbjct: 197 GSSGG----DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK 252 Query: 307 QIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366 QIGIIKTNKKTG+PMINLYTD++TGK KGEATVSFDDPPSAKAAIDWFDGKEF GN IKV Sbjct: 253 QIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKV 312 Query: 367 SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDW 426 SFATRR +F RGGG+G G RGRGG GRGG+ GRGG P ++GDW Sbjct: 313 SFATRRPEFMRGGGSGGGRRGRGGYRGRGGF-------QGRGGDP----------KSGDW 355 Query: 427 KCPNPTCENMNFSWRNECNQCKAPKPDG--PGGGP-GGSHMGGNYGDDRRGGRGGYDRGG 483 CPNP+C NMNF+ RN CNQC P+P+ P GG G GG G RGGRGG DRGG Sbjct: 356 VCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGG-DRGG 414 Query: 484 YRG--RGGDRGGFRGGRGG--GDRGGFGPGKMDSRGEHRQDR 521 Y G GG GG R GG GDR G G G S G + DR Sbjct: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDR 456 Score = 111 bits (277), Expect = 2e-24 Identities = 86/224 (38%), Positives = 98/224 (43%), Gaps = 31/224 (13%) Query: 52 QSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG 111 + S S G + GYG + +G G GG + YG S GYG S+ G Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGRGGRGG------DRGGYGGDRSGGGYG---GDRSSGG 432 Query: 112 SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS-YGQQQSYNPPQGYG--QQNQYNSSSGGG 168 Y YG +SG YGG + YG + GYG + Y GG Sbjct: 433 GYSGDRSGGGYGGDRSGG-----GYGGDRGGGYGGDRG----GGYGGDRGGGYGGDRGGY 483 Query: 169 GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 GG GGG YG D+ GG GGYG GG GGYG G R RGG GG GGG Sbjct: 484 GGDRGGG-YGGDRGGY---GGDRGGYGGDRGGYGGDRGGYG----GDRSRGGYGGDRGGG 535 Query: 229 GGGYNRSSGGYEPRGRGGGRGG-RGGMGGSDRGGF-NKFGGPRD 270 G SGGY GGG GG RGG G DRGG+ K GG D Sbjct: 536 SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRND 579 Score = 106 bits (264), Expect = 6e-23 Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 33/224 (14%) Query: 79 GGYGSSQSSQSSYGQQSSYPGYGQQP------APSSTSGSYGSSSQSS------------ 120 GG G + + Y + + G G P P+ + G+ + ++S Sbjct: 325 GGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDS 384 Query: 121 --SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178 S G + Y + Y G+ G + Y + G SS GG G GG YG Sbjct: 385 RPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYG 444 Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGS--GGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS 236 D+S GG GGGYG G GG GGYG DRGG G G GGG GG GGY Sbjct: 445 GDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG-DRGGYG-GDRGGGYGGDRGGYGGDR 502 Query: 237 GGY--EPRGRGGGRGG------RGGMGGSDRGGFNKFGGPRDQG 272 GGY + G GG RGG RGG GG DRGG + +GG R G Sbjct: 503 GGYGGDRGGYGGDRGGYGGDRSRGGYGG-DRGGGSGYGGDRSGG 545 Score = 94.7 bits (234), Expect = 2e-19 Identities = 70/158 (44%), Positives = 77/158 (48%), Gaps = 46/158 (29%) Query: 376 NRGGGNG--RGGRG--RGGPMG--RGGYGGGGSG-GGGRGGFPSGGGGGGGQQRAGDWKC 428 +RGGG G RGG G RGG G RGGYGG G GG RGG+ GG GG + G Sbjct: 471 DRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG---- 526 Query: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488 G GG GG G YG DR GG GG DR G Sbjct: 527 -------------------------GYGGDRGG---GSGYGGDRSGGYGG-DRS-----G 552 Query: 489 GDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526 G GG RGG GGDRGG+G GKM R ++R D+R RPY Sbjct: 553 GGYGGDRGGGYGGDRGGYG-GKMGGRNDYRNDQRNRPY 589 Score = 85.9 bits (211), Expect = 8e-17 Identities = 74/205 (36%), Positives = 81/205 (39%), Gaps = 48/205 (23%) Query: 40 GYSQSTDTSGYG--QSSYSSY-GQSQNTGYGTQSTPQGYGST--GGYGSSQSSQSSYGQQ 94 GY GYG +SS Y G GYG + GYG GGYG + Sbjct: 414 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGG------- 466 Query: 95 SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154 GYG G YG YG + G YGG + YG Sbjct: 467 ----GYG-----GDRGGGYG--GDRGGYGGDRGG------GYGGDRGGYG---------- 499 Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG 214 G + Y GG GG GG YG D+S GG GGG G GG SGGYG DR Sbjct: 500 -GDRGGYGGDRGGYGGDRGG--YGGDRSRGGYGGDRGGGSG----YGGDRSGGYG-GDRS 551 Query: 215 GRGRGGSGGGG-GGGGGGYNRSSGG 238 G G GG GGG GG GGY GG Sbjct: 552 GGGYGGDRGGGYGGDRGGYGGKMGG 576 Score = 67.0 bits (162), Expect = 4e-11 Identities = 100/373 (26%), Positives = 133/373 (35%), Gaps = 112/373 (30%) Query: 4 NDYTQQA--TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQS---SYSSY 58 + Y QQ+ Q G+Y Q Y QQ Y Q S +SQ + S + Q S Y Sbjct: 111 DSYDQQSGYDQHQGSYDEQ--SNYDQQHDS-YSQNQQSYHSQRENYSHHTQDDRRDVSRY 167 Query: 59 GQSQNTGY-GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG--QQPAPSSTSGSYGS 115 G+ N GY G+Q +G G G + SS G + + +G + P + + S Sbjct: 168 GE-DNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESD 226 Query: 116 SSQSSSY------------------------------GQPQSGSYSQQPSYGGQQQSYGQ 145 +S +++ G+P Y+ + + G+ + Sbjct: 227 NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDT--GKPKGEAT 284 Query: 146 QQSYNPPQGYGQQNQYNSSS-------------------GGGGGGG--GGGNYGQDQSSM 184 +PP + ++ GGG GGG G G Y Sbjct: 285 VSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQ 344 Query: 185 SSGGGSGGG--------YGNQ------------------------DQSGGGGSGGYGQQD 212 GG G GN D G G G G + Sbjct: 345 GRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 404 Query: 213 RGGRG--RGG-----SGGGGGG---GGGGY--NRSSGGYEPRGRGGGRGG-RGGMGGSDR 259 RGGRG RGG SGGG GG GGGY +RS GGY GGG GG RGG G DR Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDR 464 Query: 260 GGFNKFGGPRDQG 272 GG +GG R G Sbjct: 465 GG--GYGGDRGGG 475 Score = 60.5 bits (145), Expect = 4e-09 Identities = 55/206 (26%), Positives = 63/206 (30%), Gaps = 34/206 (16%) Query: 14 YGAYPTQPGQGYSQQSSQPY-GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72 YG + G G + S Y G +S GY GYG YG + GYG Sbjct: 415 YGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGG 474 Query: 73 QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132 G GGYG + GYG G YG YG + G Sbjct: 475 GYGGDRGGYGGDRGG-----------GYG------GDRGGYGGDR--GGYGGDRGGYGGD 515 Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192 + YGG + G GYG GGG GG GG Sbjct: 516 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR--------------GG 561 Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGR 218 GYG GG GG R R Sbjct: 562 GYGGDRGGYGGKMGGRNDYRNDQRNR 587 Score = 38.9 bits (89), Expect = 0.012 Identities = 25/53 (47%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Query: 374 DFNRGG--GNGRGGRGRGGPMGRGGYGG----GGSGGGGRGGFPSGGGGGGGQ 420 D +RGG G+ GG G GG GGYGG GG GG GG+ GG GG+ Sbjct: 522 DRSRGGYGGDRGGGSGYGGDRS-GGYGGDRSGGGYGGDRGGGYGGDRGGYGGK 573 Score = 33.5 bits (75), Expect = 0.49 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 374 DFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG 409 D + G G R G G GG G GGYGG G GG+ G Sbjct: 541 DRSGGYGGDRSGGGYGGDRG-GGYGGDRGGYGGKMG 575 >gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo sapiens] Length = 354 Score = 152 bits (384), Expect = 7e-37 Identities = 122/333 (36%), Positives = 145/333 (43%), Gaps = 86/333 (25%) Query: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48 MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+ Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59 Query: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS------TGGYGS----------SQSSQSSY 91 YGQ++Y+ SYGQ TGY T + PQ Y TG Y + S ++QS+Y Sbjct: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118 Query: 92 GQQSSYPGYGQQPA------------------PSSTSGSYGSSSQS---SSYGQPQ-SGS 129 G Q +YP YGQQPA P S++G Y S S+Y PQ GS Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178 Query: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 Y QP SY Q SY QQ +Y P YGQQ+ Y S G Sbjct: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238 Query: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 G+Y Q S S S G + Q G YGQ+ GG Sbjct: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES------------GGFS 286 Query: 229 GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 G G NRS G + RGRG G RGGM RGG Sbjct: 287 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGG 319 Score = 103 bits (257), Expect = 4e-22 Identities = 100/243 (41%), Positives = 121/243 (49%), Gaps = 57/243 (23%) Query: 7 TQQATQSYGAYP-----TQPGQGYSQ-QSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60 TQ A +YG P T+P G ++SQP Q S GY+Q + GYGQS+YS Y Q Sbjct: 120 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQP--QSSTGGYNQPS--LGYGQSNYS-YPQ 174 Query: 61 SQNTGYGTQ--STPQGYGSTGGYGSSQSS---QSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 + Y Q + P Y T Y S+Q + QSSY QQ++Y QP+ SYG Sbjct: 175 VPGS-YPMQPVTAPPSYPPTS-YSSTQPTSYDQSSYSQQNTYG----QPSSYGQQSSYG- 227 Query: 116 SSQSSSYGQ-------PQSGSYSQQPS-YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167 Q SSYGQ PQ+GSYSQ PS Y Q SYGQQ S+ +Q+ +S Sbjct: 228 --QQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSF-------RQDHPSSM--- 275 Query: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-GYGQQDRGGRGRGGSGGGGG 226 G YGQ+ SGG SG G N+ SG G G G DRGG RGG GGG G Sbjct: 276 -------GVYGQE-----SGGFSGPG-ENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG 322 Query: 227 GGG 229 G G Sbjct: 323 GMG 325 Score = 48.1 bits (113), Expect = 2e-05 Identities = 97/395 (24%), Positives = 140/395 (35%), Gaps = 79/395 (20%) Query: 38 YSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSY 97 YS YSQ+ Q YS+Y GY T Q YG Q S +YGQ + Sbjct: 6 YSTYSQAA-----AQQGYSAYTAQPTQGYA--QTTQAYG--------QQSYGTYGQPTDV 50 Query: 98 PGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQ 157 Y Q + T+ +YG ++ ++SYGQP +G Y+ + Q+Y Q P QGY Sbjct: 51 -SYTQ----AQTTATYGQTAYATSYGQPPTG-YTTPTA----PQAYSQ-----PVQGY-- 93 Query: 158 QNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS---GGGYGNQDQSGGGGSGGYGQQDRG 214 G G Y +++++ S YG Q YGQQ Sbjct: 94 ---------------GTGAYDTTTATVTTTQASYAAQSAYGTQP-----AYPAYGQQPAA 133 Query: 215 GRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG-S 273 G S+GGY G G+ P + Sbjct: 134 TAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193 Query: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333 + S Q S + + + Q T + Y +Q + + QP + +TG Sbjct: 194 SYSSTQPTSYDQSSYSQ----QNTYGQPSSYGQQSSYGQQSSYGQQPPTSY--PPQTG-- 245 Query: 334 KGEATVSFDDPPSAKAAIDWFDGKEFS---GNPIKVSFATRRADFNRGGGNGRG-GRGRG 389 S+ PS + G++ S +P + + + GG +G G R Sbjct: 246 ------SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES----GGFSGPGENRSMS 295 Query: 390 GPMGRG-GYGGGGSGGGGRGGFPSGGGGGGGQQRA 423 GP RG G GG GG RGG G GG G Q + Sbjct: 296 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGLQSES 330 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/52 (53%), Positives = 28/52 (53%), Gaps = 4/52 (7%) Query: 458 GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGG-DRGGF-RGGRGGGDRGGFG 507 G G GG G G D G RGRGG DRGG RGGRGGG RGG G Sbjct: 276 GVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGG-RGGMG 325 Score = 39.7 bits (91), Expect = 0.007 Identities = 25/45 (55%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 456 GGGPGGSHMGGNYGDDRRG-GRGGYDRGGYRGRGGDRGGFRGGRG 499 GG G G D RG GRGG+DRGG RGG RGG RGG G Sbjct: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGM-SRGG-RGGGRGGMG 325 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 148 bits (373), Expect = 1e-35 Identities = 160/575 (27%), Positives = 226/575 (39%), Gaps = 83/575 (14%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQ-PYGQQSYSGYSQ----STDTSGYGQSSYSS 57 S+ + Q ++S + Q G G SQ S YG + SG+ Q S ++G+GQ Y S Sbjct: 528 SSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQ--YGS 585 Query: 58 YGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS---------------YPGYGQ 102 G Q++G+G + G S G S+S QSSYGQ SS G+GQ Sbjct: 586 -GSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQ 644 Query: 103 QPAPSSTS---GSYGS-SSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158 + SS S G YGS S QSS +GQ SGS GQ +GQ +S + YGQ Sbjct: 645 HGSGSSQSTGFGQYGSGSGQSSGFGQHVSGS--------GQSSGFGQHESRSGHSSYGQH 696 Query: 159 NQYNSSSGG----GGGGGGGGNYGQDQSSM---------SSGGGSGGGYGNQDQSGGGGS 205 +S S G G G +GQ + S SG G G+G Q SG G S Sbjct: 697 GFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFG-QHGSGSGQS 755 Query: 206 GGYGQ-QDRGGRGRGGSGGGGGGGGGGY----NRSSGGYEPRGRGGGRG---GRGGMGGS 257 G+GQ + R G+ G G GY +R + G+ G G + G+ G G Sbjct: 756 SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSG 815 Query: 258 DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKT 317 GF + G Q S + S ++ G G + + G + + Sbjct: 816 QSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSS----------QSSGYGQHGSSS 865 Query: 318 GQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSG------NPIKVSFATR 371 GQ +G+ G S+ ++SG + S+ Sbjct: 866 GQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQH 925 Query: 372 RADFNRGGGNGRGGRGRGGPMGRGGY--GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429 + ++ G G+ G G G G + G G S G G+ G SG G GQ +G K Sbjct: 926 GSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGK-S 984 Query: 430 NPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYG-DDRRGGRGGYDRGGYRGRG 488 + ++ + S ++ Q + G G GS G G R G Y G G G Sbjct: 985 SGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSG 1044 Query: 489 GDR-GGF-RGGRGGGDRGGFGP----GKMDSRGEH 517 D+ GF + G G G GFG + S G+H Sbjct: 1045 SDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQH 1079 Score = 144 bits (364), Expect = 2e-34 Identities = 159/584 (27%), Positives = 225/584 (38%), Gaps = 107/584 (18%) Query: 11 TQSYGAYPTQPGQG-YSQQSSQPYGQQSYSGYSQ--STDTSGYGQ--------SSYSSYG 59 + +G + ++ GQ Y Q SS G SGY Q S TSG+GQ + + YG Sbjct: 603 SSGFGQHESRSGQSSYGQHSS---GSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG 659 Query: 60 QS--QNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQ----SSYPGYGQQPAPSSTSGSY 113 Q++G+G + G S G S+S SSYGQ S GYGQ + S + + Sbjct: 660 SGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGF 719 Query: 114 G----SSSQSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSS 164 G SS QSSS+GQ SGS + Q S GQ +GQ +S + YGQ + +S Sbjct: 720 GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 779 Query: 165 SGGGGGGG-----GGGNYGQDQSSMS------SGGGSGGGYGNQDQSGGGGSGGYGQQD- 212 S G G G G G +G S + SG G G+G Q SG G S G+GQ + Sbjct: 780 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFG-QHGSGSGQSSGFGQHES 838 Query: 213 ----------------RGGRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGG 253 G G+ GS G G G + SSG G+ G G G+ G Sbjct: 839 RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFG 898 Query: 254 MGGSDRGGFNKFG-----------GPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVA 302 G+ G ++ FG G GS S +++ G G++ + + Sbjct: 899 QHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQS 958 Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362 F Q G +G + + E+G K F S + ++ G+ SG+ Sbjct: 959 SGFGQHG-------SGSGQSSGFGQHESGSGKSS---GFGQHESRSSQSNY--GQHGSGS 1006 Query: 363 PIKVSFATRRADFNR--GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ 420 + + + G G R G+ G+ G G S G G+ G SG G GQ Sbjct: 1007 SQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQ 1066 Query: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG--GNYGDDRRGGRGG 478 + S ++ Q + G G GS+ G +G R G Sbjct: 1067 YESR--------------SRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQS 1112 Query: 479 YDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGK----MDSRGEH 517 G Y G GF + G G G GF + S G+H Sbjct: 1113 SGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQH 1156 Score = 122 bits (306), Expect = 8e-28 Identities = 144/566 (25%), Positives = 207/566 (36%), Gaps = 84/566 (14%) Query: 20 QPGQGYSQQSSQPYGQQSYSG---YSQSTDTSGYGQSSYSSYGQSQNTGY---------- 66 Q G G SQ S GQ Y +S S+ ++ + + G SQ+T + Sbjct: 382 QYGSGGSQSCSN--GQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQS 439 Query: 67 -GTQSTPQGYGSTGGYGSSQSSQS-SYGQQSSYPG----YGQQPAPSSTSGSYGS----S 116 G + G G T G S SSQS Y Q S G +GQ + S S +G S Sbjct: 440 SGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGS 499 Query: 117 SQSSSYGQP-----QSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG 171 QSS +GQ QS + Q S GQ +GQ +S + YGQ +S S G G Sbjct: 500 GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQY 559 Query: 172 GGGGNYGQDQSSMSSGGGSG-GGYGN---------QDQSGGGGSGGYGQQD-RGGRGRGG 220 G G Q + SG +G G YG+ Q SG G S G+GQ + R G+ G Sbjct: 560 GSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 619 Query: 221 SGGGGGGGGGGY----NRSSGGYEPRGRGGGRG---GRGGMGGSDRGGFNKFGGPRDQGS 273 G GY +R + G+ G G + G+ G G GF + Q S Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSS 679 Query: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333 + S +++ G G + + G + +GQ + +L Sbjct: 680 GFGQHESRSGHSSYGQHGFGSS----------QSSGYGQHGSSSGQT-----SGFGQHEL 724 Query: 334 KGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRG-------GGNGRGGR 386 + SF S F G+ SG+ F + + G + G Sbjct: 725 SSGQSSSFGQHGSGSGQSSGF-GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY 783 Query: 387 GRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ 446 G+ G G+G GSG GF G G G Q AG + + + ++ F + Sbjct: 784 GQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSG--QSAGFGQHGSGSGQSSGFGQHESRSH 841 Query: 447 CKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGG 505 + G G + G +G G G+ G +R G GF + G G G G Sbjct: 842 QSSYGQHGSGSSQSSGY--GQHGSSS-GQTSGF--GQHRSSSGQYSGFGQHGSGSGQSSG 896 Query: 506 FGP-----GKMDSRGEHRQDRRERPY 526 FG G+ G+H + Y Sbjct: 897 FGQHGTGSGQYSGFGQHESRSHQSSY 922 Score = 121 bits (304), Expect = 1e-27 Identities = 139/527 (26%), Positives = 188/527 (35%), Gaps = 90/527 (17%) Query: 7 TQQATQSYGAYPTQPGQ--GYSQQSSQP---YGQQSYSGYSQSTDTSGYGQSSYSSYG-- 59 ++ SYG + + Q GY Q S+ +GQ SG SQST YG S S G Sbjct: 763 SRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHG-SGSSQSTGFGQYGSGSGQSAGFG 821 Query: 60 -----QSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSSTS 110 Q++G+G + S G +GS S S YGQ S G+GQ S+S Sbjct: 822 QHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQH---RSSS 878 Query: 111 GSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGG- 169 G Y Q S G QS + Q + GQ +GQ +S + YGQ +S S G G Sbjct: 879 GQYSGFGQHGS-GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ 937 Query: 170 -GGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 G G +G Q SG SG G Q SG G S G+GQ + GSG G G Sbjct: 938 HGSSSGQTFGFGQHRSGSGQSSGFG---QHGSGSGQSSGFGQHE------SGSGKSSGFG 988 Query: 229 GGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288 S Y G G + G GS G FG R ++ Sbjct: 989 QHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQY------------- 1035 Query: 289 VQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAK 348 G G++ + + F Q G TG + + E+ + Sbjct: 1036 -SGFGQHGSGSDQSSGFGQHG-------TGSGQSSGFGQYESRSRQSSY----------- 1076 Query: 349 AAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRG 408 G+ SG+ + ++ + G G+ G G G G YG G G G Sbjct: 1077 -------GQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFG 1129 Query: 409 GFPSGGGGGGG----QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHM 464 SG G G + R+G S + C Q ++ G GP S Sbjct: 1130 QHGSGTGKSSGFAQHEYRSGQSSYGQ---HGTGSSQSSGCGQHES------GSGPTTS-- 1178 Query: 465 GGNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGK 510 +G G G + G GF + G G G G G G+ Sbjct: 1179 ---FGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222 Score = 114 bits (286), Expect = 2e-25 Identities = 170/641 (26%), Positives = 228/641 (35%), Gaps = 140/641 (21%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ-----SSYSS 57 S+ + Q ++S+ + Q G G SQ S YGQ S S TSG+GQ YS Sbjct: 830 SSGFGQHESRSHQSSYGQHGSGSSQSSG--YGQHG----SSSGQTSGFGQHRSSSGQYSG 883 Query: 58 YGQ-----SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSS 108 +GQ Q++G+G T G S G S+S QSSYGQ S GYGQ + S Sbjct: 884 FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 943 Query: 109 TSGSYGS----SSQSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159 + +G S QSS +GQ SGS + Q S G+ +GQ +S + YGQ Sbjct: 944 QTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHG 1003 Query: 160 QYNSSSGGGGGGGGG--------------GNY--------GQDQSS----MSSGGGSGGG 193 +S S G G G G Y G DQSS +G G G Sbjct: 1004 SGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSG 1063 Query: 194 YGN-----------QDQSGGGGSGGYGQ------------QDRGGRGRG------GSGGG 224 +G Q SG S GYGQ Q R G G+ GSG G Sbjct: 1064 FGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG 1123 Query: 225 GGGG----GGGYNRSSGGYEPRGRGG----GRGGRGGMGGSDRGGFNKFGGPRDQGSRHD 276 G G G +SSG + R G G+ G G S G GP +H Sbjct: 1124 QSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHV 1183 Query: 277 SEQDN----------SDNNTIFVQ-----------GLGENVTIESVADYFKQIGI----- 310 S DN S +T F Q G GE+ +ES + + Sbjct: 1184 SGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQT 1243 Query: 311 IKTNK--KTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA---IDWFDGKEFSGNPIK 365 I T + ++GQ R T + + + + D +K + + + S P Sbjct: 1244 INTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKS 1303 Query: 366 VSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGD 425 S RR G RG R G G G GS GR F S + +G Sbjct: 1304 GSTVRRRQGTTHGQ---RGDTTRHGHSGHGQSTQTGSRTSGRQRF-SHSDATDSEVHSGV 1359 Query: 426 WKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR 485 P+ E +A G YG + G G+ G+ Sbjct: 1360 SHRPHS----------QEQTHSQAGSQHGESESTVHERHETTYG--QTGEATGHGHSGH- 1406 Query: 486 GRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY 526 G+ RG GR G ++ S G HR +E+ + Sbjct: 1407 GQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTH 1447 Score = 80.5 bits (197), Expect = 3e-15 Identities = 120/533 (22%), Positives = 189/533 (35%), Gaps = 59/533 (11%) Query: 2 ASNDYTQQATQSYGAYPTQPGQGYSQQS-SQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ 60 +S + ++ +S+ + + G+ Y S S + ++ + G S +TSG+ +S S + Sbjct: 200 SSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIR 259 Query: 61 SQNTGY--------GTQSTPQGYGSTGGYGSSQSSQSS-----YGQQSSYPGYGQQPAPS 107 Q G G +S GY ++ G G Q++ SS +G Q + Y Q S Sbjct: 260 EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQS 319 Query: 108 STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG 167 G G S GGQ GQ +S Q Y Q+ +G Sbjct: 320 GIKGGQGHGCVS-----------------GGQPSGCGQPESNPCSQSYSQRGYGARENGQ 362 Query: 168 GGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227 GG G QSS GSGG QS G YG R + Sbjct: 363 PQNCGGQWRTGSSQSSCCGQYGSGG-----SQSCSNGQHEYGSCGRFSNSSSSNEFSKCD 417 Query: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG--GFNKFGGPRDQGSRHDSEQDNSDNN 285 G + S +E G G + G ++ G + G + S D ++ Sbjct: 418 QYGSGSSQSTSFEQHGTGLSQS-----SGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSS 472 Query: 286 TIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPP 345 + G G++ + + F Q G +GQ + G + G+++ F Sbjct: 473 SGKTSGFGQHGSGSGQSSGFGQCG-----SGSGQSS----GFGQHGSVSGQSS-GFGQHG 522 Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405 S F E + S+ + ++ G G+ G G+ G G G S G Sbjct: 523 SVSGQSSGFGQHESRSR--QSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGF 580 Query: 406 GRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG 465 G+ G SG G GQ +G + + ++ + S ++ Q + G G GS Sbjct: 581 GQYGSGSGQSSGFGQHGSGSGQ-SSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQT 639 Query: 466 GNYGDDRRGGRGGYDRGGYRGRGGDRGGF-RGGRGGGDRGGFGPGKMDSRGEH 517 +G G G Y G GF + G G GF G+ +SR H Sbjct: 640 SGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF--GQHESRSGH 690 Score = 63.2 bits (152), Expect = 6e-10 Identities = 122/514 (23%), Positives = 175/514 (34%), Gaps = 64/514 (12%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85 +Q+ SQ +S G+S S +G SS + N + + S G G GS+ Sbjct: 173 NQEGSQKRYHRSSCGHSWSGGKDRHGSSSVE-LRERINKSHISPSRESGEEYESGSGSNS 231 Query: 86 SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145 + G+G TSG +S+QS Q S S G + + G Sbjct: 232 WERK---------GHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACG- 281 Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG--GGSGGGYGNQDQSGGG 203 Y+ G G+ +SS GG G + QS SG GG G G + Q G Sbjct: 282 ---YSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGC 338 Query: 204 G-------SGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSS--GGYEPRGRGGGRGGRGGM 254 G S Y Q+ G R G GG G ++SS G Y G GG + G Sbjct: 339 GQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQY---GSGGSQSCSNGQ 395 Query: 255 GGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTN 314 G ++ S+ D S +T F Q + T S + F+Q + + Sbjct: 396 HEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQ----HGTGLSQSSGFEQ-HVCGSG 450 Query: 315 KKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRAD 374 + GQ + ++ +D S+ F G+ SG+ Sbjct: 451 QTCGQH-----------ESTSSQSLGYDQHGSSSGKTSGF-GQHGSGS------------ 486 Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGG--GGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPT 432 + G G+ G G G G G +G G S G G+ G SG G GQ + + Sbjct: 487 -GQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQ 545 Query: 433 CENMNFSWRNECNQCKAPKPDGPGG---GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGG 489 S + Q + + G G G G S G YG G G G+ Sbjct: 546 -HGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSS 604 Query: 490 DRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRE 523 G G G G S G + R+ Sbjct: 605 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ 638 Score = 57.8 bits (138), Expect = 2e-08 Identities = 74/288 (25%), Positives = 109/288 (37%), Gaps = 48/288 (16%) Query: 9 QATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT 68 Q+TQ + G G+S+ S + +SG S + YGQ+ S +G+S + +G Sbjct: 2089 QSTQRGSRTAGRRGSGHSESSDS----EVHSGVSHTHSGHTYGQAR-SQHGESGSAIHGR 2143 Query: 69 QSTPQG-------YGSTGGYGSSQSSQSSYGQQ-SSYPGYGQQPAPSSTSGSYGSSSQS- 119 Q T G +G +G S+Q+ + G+Q SS+ S S ++ + S Sbjct: 2144 QGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQ 2203 Query: 120 --SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177 S +GQ S + +Q + GQ + Y GYGQ Q S + G G G + Sbjct: 2204 AGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHY----GYGQSTQRGSRTTGRRGSGHSESS 2259 Query: 178 GQDQSSMSSGGGSG---GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG-----G 229 + S S SG G G+Q + G G + G G G G G G Sbjct: 2260 DSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTG 2319 Query: 230 GGYNRSS--------------------GGYEPRGRGGGRGGRGGMGGS 257 +R+S G Y P G G G GGS Sbjct: 2320 SRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGS 2367 Score = 54.7 bits (130), Expect = 2e-07 Identities = 118/572 (20%), Positives = 192/572 (33%), Gaps = 96/572 (16%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-----------SSYGQSQN----------- 63 +Q S+ G++ SG+S+ +D+ GY S+ S +G+S++ Sbjct: 1714 TQTGSRTTGRRG-SGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772 Query: 64 -TGYGTQSTPQGYGSTGGYGS-----SQSSQSSYGQQSSYPGYGQQP-APSSTSGSYGSS 116 TG T+ G+G + GS S S Y + G+ Q+P + T G GS Sbjct: 1773 QTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQ 1832 Query: 117 SQSS----------SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG 166 S ++GQ S Q +G QS G + G+ + + SG Sbjct: 1833 HGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQS-GSSTTGRRRSGHSESSDSEVHSG 1891 Query: 167 GGGGGGG------GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGY----GQQDRGGR 216 G G +G+ +S++ + G G S G G + G R Sbjct: 1892 GSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRR 1951 Query: 217 GRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG------------------------RGGRG 252 G G S G G + + G+ G+ G R G Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSGH-THGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHS 2010 Query: 253 GMGGSDRGGFNKFGGPRDQGSRHDSEQDN----SDNNTIFVQGLGENVTIESVADYFKQI 308 G G S + G ++ G R G S+ + S ++ G + ES + ++ Sbjct: 2011 GHGQSTQRG-SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERH 2069 Query: 309 GIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSF 368 G T+ +TG + ++ +G T ++++ D + SG S Sbjct: 2070 G--TTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESS----DSEVHSGVSHTHSG 2123 Query: 369 ATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKC 428 T ++ G +G GR G + G G G G G+QR+ + Sbjct: 2124 HTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSES 2183 Query: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG---GNYGDDRRGGRGGYDRGGYR 485 + + + +A G G G G G GD R GY Sbjct: 2184 SDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGY------ 2237 Query: 486 GRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517 G+ RG GR G ++ S G H Sbjct: 2238 GQSTQRGSRTTGRRGSGHSESSDSEVHSWGSH 2269 Score = 46.6 bits (109), Expect = 6e-05 Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 50/353 (14%) Query: 19 TQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSY-----------SSYGQSQNTGYG 67 +Q GQG S Q+ ++ S S+++D+ + + S+ S Y +S +T Sbjct: 1250 SQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRR 1309 Query: 68 TQSTPQGY-GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126 Q T G G T +G S QS+ S TSG S ++ + Sbjct: 1310 RQGTTHGQRGDTTRHGHSGHGQSTQ-------------TGSRTSGRQRFSHSDATDSEVH 1356 Query: 127 SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD-QSSMS 185 SG S +P Q S Q ++++ G G G +GQ Q Sbjct: 1357 SG-VSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSR 1415 Query: 186 SGGGSGGGYG----------------NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGG 229 + G G G+ +Q+Q+ G +G+ GR G+ G G Sbjct: 1416 TTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDT 1475 Query: 230 GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFV 289 + G + RG GR G G S+ G S H Q S + Sbjct: 1476 TRHAHYHHGKSTQ-RGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQH----- 1529 Query: 290 QGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 342 G E++ + Q G + +G R TG+ + + S D Sbjct: 1530 -GESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTD 1581 Score = 43.5 bits (101), Expect = 5e-04 Identities = 63/305 (20%), Positives = 111/305 (36%), Gaps = 35/305 (11%) Query: 6 YTQQATQSYGAYPTQPGQGYS---QQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQ 62 ++Q+ T S +Q G+ S ++ YGQ +G + SG+GQS+ + Sbjct: 1364 HSQEQTHSQAG--SQHGESESTVHERHETTYGQ---TGEATGHGHSGHGQSTQRGSRTTG 1418 Query: 63 NTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY 122 G G + +GG QS + ++GQ S G ++G + ++ + Sbjct: 1419 RRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRH 1478 Query: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G +Q+ S ++ G +S + G + ++ G G G +G+ +S Sbjct: 1479 AHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHS----GHTHGQSGSQHGESES 1534 Query: 183 SM---------SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG------ 227 + +G + Y +Q+ GS G+Q S GG Sbjct: 1535 IIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHS 1594 Query: 228 -----GGGGYNRSSGGYEPRGRGGGRGGRGG--MGGSDRG-GFNKFGGPRDQGSRHDSEQ 279 G G + R G G+ G G S G G + G R G + S Sbjct: 1595 REHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHS 1654 Query: 280 DNSDN 284 ++SD+ Sbjct: 1655 ESSDS 1659 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 139 bits (350), Expect = 6e-33 Identities = 150/509 (29%), Positives = 193/509 (37%), Gaps = 52/509 (10%) Query: 22 GQGYSQQSSQ-PYGQQSYSGYSQSTDT--SGYGQSSYSSYGQS---QNTGYGTQSTPQGY 75 G G Q SS PY +S SG+S S SG G SS + +S Q++GYG + G+ Sbjct: 1015 GSGSGQSSSYGPY--RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 1072 Query: 76 GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQP 134 ST G S S GQ SS +G SS+ G +GS SSQSS YG+ SGS Q P Sbjct: 1073 SSTHGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSP 1126 Query: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194 +G Q+ G +QS P G SSS G G G G + G SSG S Sbjct: 1127 GHG--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS--- 1179 Query: 195 GNQDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGG 253 +Q SG G S GYGQ R G+ G G G + G + G GR G G Sbjct: 1180 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS 1239 Query: 254 MGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT 313 RG G +H S S + + G + + G Sbjct: 1240 GHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF---GQHESGSGHSSA 1296 Query: 314 NKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRA 373 + G + + + G G+++ +FD S+ + G SG+ + A Sbjct: 1297 YSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGA 1354 Query: 374 DFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431 + GR G G G G+ G G G S GR G SG G G + W+ Sbjct: 1355 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQ---- 1410 Query: 432 TCENMNFSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGG 489 + C Q G G G S+ G G RG R G G G Sbjct: 1411 ---------SSGCTQ------HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 1455 Query: 490 DRGGFRGGRGGGDRG-GFGPGKMDSRGEH 517 G R G G G G G SRG H Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484 Score = 136 bits (343), Expect = 4e-32 Identities = 150/540 (27%), Positives = 214/540 (39%), Gaps = 75/540 (13%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61 S+ + +Q + S G P++ G S +GQ SG +S+ Y +S +SS Sbjct: 2169 SSGHGRQGSGS-GHSPSRGRHGSGSGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 2226 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119 +G G S +GS G+ SQ S+ GQ S++ G SS+ G +GS SSQS Sbjct: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286 Query: 120 SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178 SSYGQ SGS Q PS G G SY +G + ++SSSG G G G +G Sbjct: 2287 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 2342 Query: 179 QDQSS--MSSG---GGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN 233 +SS SSG GSG G+ + + G SG + +R G G S G G G + Sbjct: 2343 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG--S 2400 Query: 234 RSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFG---------GPRDQGSRHDSEQ 279 R S G+ G G G+ GR G G ++ +G GP + GS H S Sbjct: 2401 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGL 2460 Query: 280 DNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATV 339 + ++ + G G++ G + T + G G++ Sbjct: 2461 GHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSTSGQS-- 2496 Query: 340 SFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRGGY 397 S A + G+ SG+ + + + + G+G+ G G R P GR G Sbjct: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556 Query: 398 GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGG 457 G G S G+ G G G G + + ++ ++S G G Sbjct: 2557 GSGRSSSSGQHGSGLGESSGFGHHESS-------SGQSSSYSQHG----------SGSGH 2599 Query: 458 GPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517 G G G RG R G G G G R G G R G G G+ SRG H Sbjct: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-RQGSGSGQSPSRGRH 2658 Score = 133 bits (335), Expect = 3e-31 Identities = 153/542 (28%), Positives = 211/542 (38%), Gaps = 79/542 (14%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGY-GQSSYSSYGQS 61 S+ + +Q + S G P++ G S +GQ SG +S+ Y +S +SS Sbjct: 1699 SSGHGRQGSGS-GQSPSRGRHGSGLGHSSSHGQHG-SGSGRSSSRGPYESRSGHSSVFGQ 1756 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQ-SSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQS 119 +G G S +GS G+ SQ S+ GQ S++ G SS+ G +GS SSQS Sbjct: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816 Query: 120 SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG-GGGGGGGGGNYG 178 SSYGQ SGS Q PS G G SY +G + ++SSSG G G G +G Sbjct: 1817 SSYGQQGSGS-GQSPSRGRHGSGSGHSSSYGQ---HGSGSGWSSSSGRHGSGSGQSSGFG 1872 Query: 179 QDQSS--MSSG---GGSGGGY----------------GNQDQSGGGGSGGYGQQDRGGRG 217 +SS SSG GSG G+ G Q S G S YGQ G R Sbjct: 1873 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQ 1932 Query: 218 RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDS 277 G G G G G + S G + G G G+ G GS G++ GP + GS H S Sbjct: 1933 SLGHGQHGSGSGQSPSPSRGRH---GSGSGQSSSYGPYGSG-SGWSSSRGPYESGSGHSS 1988 Query: 278 EQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEA 337 + ++ + G G++ G + T + G G++ Sbjct: 1989 GLGHRESRSGQSSGYGQH----------------------GSSSGHSSTHGQHGSASGQS 2026 Query: 338 TVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG-RGGP-MGRG 395 S A + G+ SG+ + + + + G+G+ G G R P GR Sbjct: 2027 --SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084 Query: 396 GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGP 455 G G G S G+ G G G G + + ++ ++S G Sbjct: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESS-------SGQSSSYSQHG----------SGS 2127 Query: 456 GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515 G G G G RG R G G G G R G G R G G G SRG Sbjct: 2128 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG-RQGSGSGHSPSRG 2186 Query: 516 EH 517 H Sbjct: 2187 RH 2188 Score = 130 bits (326), Expect = 4e-30 Identities = 143/543 (26%), Positives = 191/543 (35%), Gaps = 94/543 (17%) Query: 22 GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTPQGY 75 G G Q SS PYG S SG+S S G S S G Q++GYG + G+ Sbjct: 1485 GSGSGQSSSYSPYG--SGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH 1542 Query: 76 GSTGGYGSSQSSQSSY--------GQQSSY----------PGYGQQPAPSSTS---GSYG 114 ST G S S QSS GQ SS+ GYG+Q + S S G G Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602 Query: 115 SSS-QSSSYGQPQSG-----SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168 S S QS SYG+ SG S Q S G+ +G +S + GQ + Y+ G Sbjct: 1603 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS-----GQSSSYSQHGSGS 1657 Query: 169 GGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGG 228 G G G +G S G G + + G GS G + G GR GSG G Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS---GSRQSSGHGRQGSGSGQSPS 1714 Query: 229 GGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNT 286 G + G G+ G GR G R G + G + GS H S + + Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1774 Query: 287 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPS 346 G++ + + F Q G TGQ + Sbjct: 1775 GHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------- 1806 Query: 347 AKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGG 404 G+ SG+ S+ + + + GR G G G G+ G G G S Sbjct: 1807 ---------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857 Query: 405 GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQ-----CKAPKPDGPGGGP 459 GR G SG G G + W+ T + Q ++ + + G Sbjct: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917 Query: 460 GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGP-----GKMDSR 514 G S G +G R G G G+ R G G G +GP G SR Sbjct: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR 1977 Query: 515 GEH 517 G + Sbjct: 1978 GPY 1980 Score = 128 bits (321), Expect = 1e-29 Identities = 138/533 (25%), Positives = 185/533 (34%), Gaps = 116/533 (21%) Query: 22 GQGYSQQSSQ-PYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77 G G Q SS PYG S S+ SG G SS + +S Q++GYG + G+ S Sbjct: 1955 GSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2014 Query: 78 TGG-YGSSQSSQSSYGQQSSYPG----YGQQPAPSSTSGSYG----SSSQSSSYGQPQSG 128 T G +GS+ SS GQ + G +GQ + SS S YG S QS +GQ SG Sbjct: 2015 THGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2074 Query: 129 SYSQQPSYGGQQQSYGQQQS---YNPPQGY-----------GQQNQYNSSSGGGGGGGGG 174 S Q PSYG G+ S + P G GQ + Y+ G G G Sbjct: 2075 S-RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2133 Query: 175 GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234 G +G S G G G+ + G GSG + G GR GSG G G + Sbjct: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS---RQSSGHGRQGSGSGHSPSRGRHGS 2190 Query: 235 SSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGL 292 SG G+ G GR G R G + G + GS H S + + Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250 Query: 293 GENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAID 352 G++ + + F Q G TGQ + Sbjct: 2251 GQHGSTSGQSSTFDQEG-----SSTGQSSSH----------------------------- 2276 Query: 353 WFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRG--GPMGRGGYGGGGSGGGGRGGF 410 G+ SG+ S+ + + + GR G G G G+ G G G S GR G Sbjct: 2277 ---GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333 Query: 411 PSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGD 470 SG G G + W+ T G G G S+ Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYT-------------------QHGSGSGHSSSY------- 2367 Query: 471 DRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRE 523 ++ G R G G+R G G S G+H R+ Sbjct: 2368 EQHGSRSGQS------------------SRGERHGSSSGSSSSYGQHGSGSRQ 2402 Score = 125 bits (315), Expect = 7e-29 Identities = 146/560 (26%), Positives = 198/560 (35%), Gaps = 90/560 (16%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDT----SGYGQSSYSSY 58 S+ Y Q ++S G G S SS YGQ SG QS SG GQS S Sbjct: 954 SSSYEQHGSRS-GQSSRSEQHGSSSGSSSSYGQHG-SGSRQSLGHGQHGSGSGQSPSPSR 1011 Query: 59 GQ-----SQNTGYGTQSTPQGYGSTGG---YGSSQSS-----QSSYGQQSSYPGYGQQPA 105 G+ Q++ YG + G+ S+ G GS SS +S GQ S Y +G Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071 Query: 106 PSSTSGSYGSSS-QSSSYGQP-----QSGSYSQQPSYGGQQQSYGQQQSYNPPQ-GYGQQ 158 SST G +GS+S QSSS GQ QS S+ Q S Q YG+Q S + G+GQ+ Sbjct: 1072 HSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1131 Query: 159 NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG------------GGSG 206 + S G G G SG G G+G+ + S G G S Sbjct: 1132 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 1191 Query: 207 GYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265 GYGQ R G+ G G G + G + G GR G G RG Sbjct: 1192 GYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG 1251 Query: 266 GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325 G +H S S + + G + + G + G + Sbjct: 1252 LGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF---GQHESGSGHSSAYSQHGSGSGHFC 1308 Query: 326 TDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGG 385 + + G G+++ +FD S+ + G SG+ + A + GR G Sbjct: 1309 SQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGSGQSPSRGRHG 1366 Query: 386 RGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443 G G G+ G G G S GR G SG G G + W+ Sbjct: 1367 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG------------- 1413 Query: 444 CNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDR 503 C Q G G G S+ ++ G R G G+R Sbjct: 1414 CTQ------HGSGSGHSSSY-------EQHGSRSGQS------------------SRGER 1442 Query: 504 GGFGPGKMDSRGEHRQDRRE 523 G G S G+H R+ Sbjct: 1443 HGSSSGSSSSYGQHGSGSRQ 1462 Score = 124 bits (310), Expect = 3e-28 Identities = 149/530 (28%), Positives = 202/530 (38%), Gaps = 64/530 (12%) Query: 20 QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGTQSTPQGYGS 77 Q G G SQ SS YGQQ S SG S S G G SSYGQ +G+ + S G GS Sbjct: 2278 QHGSGSSQSSS--YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335 Query: 78 --TGGYGSSQSSQ----------SSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQ 124 + G+G +SS S G SSY +G + SS +GSSS SSSYGQ Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395 Query: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184 SGS + S G Q G QS +P +G SSS G G G + + Sbjct: 2396 HGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG--WSSSRGPY 2450 Query: 185 SSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG-----RGRGGSGGGGGGGGGGYNRSSGGY 239 SG G G G+++ S G S GYGQ G+ GS G G + SSG Sbjct: 2451 ESGSGHSSGLGHRE-SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 2509 Query: 240 EPRGRGG-------GRGGRGGMGGSDRGGFNKFGGPRDQGS--RHDSEQDNSDNNTIFVQ 290 G+ G G G +G G G + G R S RH S S ++ Sbjct: 2510 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 2569 Query: 291 GLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAA 350 GLGE+ + G + + G + + G G+++ S+ ++ Sbjct: 2570 GLGES---SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626 Query: 351 IDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF 410 + G+ SG+ + + + GR G G G G +G G RG + Sbjct: 2627 SHY--GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 2684 Query: 411 PSGGGGGG--GQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNY 468 S G GQ +G + + C+Q G GS G + Sbjct: 2685 ESRLGHSSVFGQHESGSGH--SSAYSQHGSGSGHFCSQ-----------GQHGSTSGQSS 2731 Query: 469 GDDRRGGRGGYDRG-GYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517 D+ G G G+RG G + G R G G G+ S G H Sbjct: 2732 TFDQEGSSTGQSSSYGHRGSGSSQSS------GYGRHGAGSGQSLSHGRH 2775 Score = 123 bits (309), Expect = 4e-28 Identities = 153/550 (27%), Positives = 207/550 (37%), Gaps = 92/550 (16%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70 + SYG Q G G S QSS Q S SG+S S G SS+GQ G GT Sbjct: 749 SSSYG----QHGSG-SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH---GSGTSC 800 Query: 71 TPQ------GYGSTGGYGSSQS-SQSSYGQQSSYPGY-------GQQPAPSSTSGSYGSS 116 + G G G+G +S S Y Q S G+ G SS+SG + SS Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS 860 Query: 117 S-QSSSYGQPQSGSY------------SQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNS 163 S QSSSYGQ +S S+ Q P +G + GQ SY +G + +S Sbjct: 861 SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGR---HGSGSGRSS 917 Query: 164 SSGGGGGGGG-GGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218 SSG G G G +G SS S G GSG G+ + + G SG + ++ G Sbjct: 918 SSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSS 977 Query: 219 GGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG-----GRGGMGGSDRGGFNKFGGPRDQGS 273 G S G G G +R S G+ G G G+ GR G G + GP GS Sbjct: 978 GSSSSYGQHGSG--SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY----GPYRSGS 1031 Query: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333 S + ++ + GLG + + + Q G + T + G Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST---------HGQHGST 1082 Query: 334 KGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMG 393 G+++ S+ + G+ SG+ ++ G GR G G G G Sbjct: 1083 SGQSSSCGQHGASSGQSSS--HGQHGSGS-------------SQSSGYGRQGSGSGQSPG 1127 Query: 394 RGGYGGGG--SGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPK 451 G G G S GR G SG GQ +G E+ F +E + ++ Sbjct: 1128 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-------LGESSGFG-HHESSSGQSSS 1179 Query: 452 PDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKM 511 G G G S G +G R G+ RG G G G G R G G+ Sbjct: 1180 YSQHGSGSGHSSGYGQHGS--RSGQSS--RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235 Query: 512 DSRGEHRQDR 521 S H R Sbjct: 1236 GSGSGHSPSR 1245 Score = 123 bits (309), Expect = 4e-28 Identities = 155/557 (27%), Positives = 195/557 (35%), Gaps = 143/557 (25%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPY----GQQSYSGY--SQSTDTSGYGQSSYSS------- 57 + SYG Y + G G+S S PY G S G+ S+S +SGYGQ SS Sbjct: 1961 SSSYGPYGS--GSGWSS-SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 2017 Query: 58 -----YGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSS 108 GQS + G S+ Q S G +GS S S YG+Q S PG+GQ+ + S Sbjct: 2018 QHGSASGQSSSCGQHGASSGQS-SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076 Query: 109 TSGSYG----SSSQSSSYGQP------------------QSGSYSQQPSYGGQQQSYGQQ 146 S SYG S +SSS GQ QS SYSQ S G YGQ Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2136 Query: 147 QSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG 206 S + G++ + SSS G YGQ SG G+G Q G GSG Sbjct: 2137 GSRSGQSSRGER--HGSSS------GSSSRYGQH----GSGSRQSSGHGRQ----GSGSG 2180 Query: 207 GYGQQDRGGRGRG-GSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265 + R G G G S G G G G + S G YE R G + Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYE-----------------SRSGHSSV 2223 Query: 266 GGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325 G + GS H S + + G++ + + F Q G TGQ + Sbjct: 2224 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG-----SSTGQSSSH-- 2276 Query: 326 TDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGG 385 G+ SG+ S+ + + + GR G Sbjct: 2277 ------------------------------GQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306 Query: 386 RGRG--GPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443 G G G+ G G G S GR G SG G G + W+ T Sbjct: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT----------- 2355 Query: 444 CNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGG 501 G G G S+ G G RG R G G G G R G G Sbjct: 2356 --------QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407 Query: 502 DRG-GFGPGKMDSRGEH 517 G G G SRG H Sbjct: 2408 QHGSGSGQSPSPSRGRH 2424 Score = 123 bits (309), Expect = 4e-28 Identities = 121/403 (30%), Positives = 160/403 (39%), Gaps = 27/403 (6%) Query: 22 GQGYSQQSS-QPYGQQSYSGYSQSTDTSGYGQSSYSSYGQS---QNTGYGTQSTPQGYGS 77 G G Q SS PYG S S+ SG G SS + +S Q++GYG + G+ S Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484 Query: 78 TGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSSSYGQPQSGSYSQQPSY 136 T G S S GQ SS +G SS+ G +GS SSQSS YG+ SGS Q P + Sbjct: 2485 THGQHGSTS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGH 2538 Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196 G Q+ G +QS P G SSS G G G G + G SSG S + Sbjct: 2539 G--QRGSGSRQS--PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS---YS 2591 Query: 197 QDQSGGGGSGGYGQQ-DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMG 255 Q SG G S GYGQ R G+ G G G + G + G GR G G Sbjct: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651 Query: 256 GSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNK 315 RG G +H S S + + LG + + G Sbjct: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVF---GQHESGSGHSSAYS 2708 Query: 316 KTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADF 375 + G + + + G G+++ +FD S+ + G SG+ + A Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSSTGQSSSY-GHRGSGSSQSSGYGRHGAGS 2766 Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGG 418 + +GR G G G YG GSG G G+ G G G Sbjct: 2767 GQSLSHGRHGSGSG---QSSSYGQHGSGSGQSSGYSQHGSGSG 2806 Score = 122 bits (305), Expect = 1e-27 Identities = 155/564 (27%), Positives = 194/564 (34%), Gaps = 90/564 (15%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT 68 AT + Q G G SQ S YGQQ S SG S S G SSYGQ +G G Sbjct: 628 ATSGQSSSHGQHGSGSSQSSR--YGQQGSGSGQSPSRGRHGSDFGHSSSYGQ-HGSGSGW 684 Query: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYP----------GY---GQQPAPSSTSGSYGS 115 S+ +GS G S +S GQ S Y GY G + SS S +GS Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744 Query: 116 SSQ-SSSYGQPQSGSYSQQPSYGGQQQSYGQQ-------QSYNPPQGYGQQNQYNSSSGG 167 SS SSSYGQ SGS+ Q +G Q G S +GQ S S Sbjct: 745 SSGLSSSYGQHGSGSH-QSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803 Query: 168 GG----GGGGGGNYGQDQSSMSSG----GGSGGGYGNQDQSGG---------------GG 204 G G G +GQ +S G G + G + +Q + G G Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863 Query: 205 SGGYGQQDRG-----GRGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGGMGG 256 S YGQ + GRGR GSG G G G SG Y G G GR G G Sbjct: 864 SSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG 923 Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316 S G + FG H S S T G G + + E + + Sbjct: 924 SGSGQSSGFG--------HKSSSGQSSGYTQHGSGSGHSSSYE------------QHGSR 963 Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376 +GQ + G G ++ ++ ++ SG S + Sbjct: 964 SGQSS----RSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1019 Query: 377 RGGGNGRGGRGRGGPMGRGGY--GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCE 434 + G G G RG Y G G S G G SG G GQ + Sbjct: 1020 QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079 Query: 435 NMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRG-GYRGRGGDRGG 493 + C Q A G GS + G R+G G G G RG G + Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 1139 Query: 494 FRGGRGGGDRGGFGPGKMDSRGEH 517 G R G G G+ S G+H Sbjct: 1140 SYG------RHGSGSGRSSSSGQH 1157 Score = 121 bits (303), Expect = 2e-27 Identities = 145/539 (26%), Positives = 193/539 (35%), Gaps = 73/539 (13%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS 61 S+ Y+Q + S G + +Q G + S + Q+ S +G S S G G S SSYGQ Sbjct: 1764 SSAYSQHGSGS-GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS-SSQSS 120 G G+ +P S G +GS SSYGQ S G+ SS+SG +GS S QSS Sbjct: 1823 ---GSGSGQSP----SRGRHGSGSGHSSSYGQHGSGSGW------SSSSGRHGSGSGQSS 1869 Query: 121 SYGQPQSGS-----YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGG 175 +G +S S Y+Q S G SY Q S + G+Q+ +S S G G G Sbjct: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSG 1929 Query: 176 N----------YGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGG 225 + G QS S G G G G G GSG RG G G Sbjct: 1930 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSG 1989 Query: 226 GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GFNKFGGPRDQGSRHDSEQDNS 282 G + S GY G G G GS G + G Q S H S Sbjct: 1990 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGS 2049 Query: 283 DNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD 342 ++ G G + + Q G +G Y +G G ++ S Sbjct: 2050 SQSS----GYGRQGSGSGQSPGHGQRG-------SGSRQSPSYGRHGSG--SGRSSSSGQ 2096 Query: 343 DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402 P + + + SG S++ + G G+ G R G RG G S Sbjct: 2097 HGPGLGESSGFGHHESSSGQ--SSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHGSSS 2153 Query: 403 GGGGRGGFPSGG---GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459 G R G G G G+Q +G P + G G G Sbjct: 2154 GSSSRYGQHGSGSRQSSGHGRQGSGSGHSP-------------------SRGRHGSGSGH 2194 Query: 460 GGSHMGGNYGDDRRGGRGGYD-RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEH 517 SH G R RG Y+ R G+ G G + G G G S+G+H Sbjct: 2195 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253 Score = 119 bits (298), Expect = 7e-27 Identities = 145/563 (25%), Positives = 207/563 (36%), Gaps = 71/563 (12%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQ---SSYSSYG 59 S+ YTQ + S + + GQ S+ G++ S S S YGQ S S G Sbjct: 475 SSGYTQHGSGS--GHSSGHGQHGSRSGQSSRGERQGSSAGSS---SSYGQHGSGSRQSLG 529 Query: 60 QSQN-TGYGTQSTP-QGYGSTG----------GYGSSQ-SSQSSYGQQSSY-PGYGQQPA 105 S++ +G G +P +G +G GYGS + SS+ Y S + G G Q + Sbjct: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES 589 Query: 106 PSSTSGSYG----SSSQSSSYGQ-----PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYG 156 S S YG SS SS++GQ QS S Q + GQ S+GQ S G Sbjct: 590 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGS-----GSS 644 Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSG-----GGGSGGYGQQ 211 Q ++Y G G G +G D SS G G G G +G G S G+G + Sbjct: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHK 704 Query: 212 DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRG---GFNKFGGP 268 G+ G S G G + S GY G G+ R GS G + + G Sbjct: 705 SGSGQSSGYSQHGSG------SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758 Query: 269 RDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKT--NKKTGQPMINLYT 326 Q S H + S ++ V+ + S + + + ++G + + Sbjct: 759 SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFG 818 Query: 327 DRETGKLKG-------EATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGG 379 E+G +G S + + G+ S + S+ + + Sbjct: 819 QHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHAS 878 Query: 380 GNGRGGRGRGGPMGRG--GYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437 G GR G G G G G G G G S GR G SG G+ +G + ++ Sbjct: 879 GRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG-------SGQSSG 931 Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSH--MGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 F ++ Q G G G S+ G G R + G G G G R Sbjct: 932 FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR 991 Query: 496 GGRGGGDRG-GFGPGKMDSRGEH 517 G G G G G SRG H Sbjct: 992 QSLGHGQHGSGSGQSPSPSRGRH 1014 Score = 119 bits (297), Expect = 9e-27 Identities = 143/518 (27%), Positives = 196/518 (37%), Gaps = 78/518 (15%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYGQ-QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ 69 + S G Y ++ G S +GQ +S SG+S + G G + S GQ +T G Sbjct: 1268 SSSRGPYESRSGH------SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS-GQS 1320 Query: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTS---GSYGSSS-QSSSYGQP 125 ST GS+ G SS + S QSS GYG+ A S S G +GS S SSSYGQ Sbjct: 1321 STFDQEGSSTGQSSSYGHRGSGSSQSS--GYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378 Query: 126 QSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMS 185 SGS S G GQ + G+ + + + SS G G G + +Q Sbjct: 1379 GSGS-GWSSSSGRHGSGSGQSSGF----GHHESSSWQSSGCTQHGSGSGHSSSYEQHGSR 1433 Query: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245 SG S G + S G S YGQ G R G G G G G + S G + G G Sbjct: 1434 SGQSS---RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH---GSG 1487 Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYF 305 G+ GS G++ GP + GS H S + ++ + G G++ Sbjct: 1488 SGQSSSYSPYGSG-SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQH---------- 1536 Query: 306 KQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIK 365 G + T + G G+++ G+ + + Sbjct: 1537 ------------GSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQS 1569 Query: 366 VSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGG--SGGGGRGGFPSGGGGGGGQQRA 423 S + ++ G GR G G G G G G G S GR G SG GQ + Sbjct: 1570 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1629 Query: 424 GDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG 483 G E+ F +E + ++ G G G S G +G R G +R G Sbjct: 1630 G-------LGESSGFG-HHESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQSSRGERHG 1680 Query: 484 YRGRGGDRGGFRGG----RGGGDRGGFGPGKMDSRGEH 517 R R G G G R G G G+ SRG H Sbjct: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718 Score = 115 bits (287), Expect = 1e-25 Identities = 146/574 (25%), Positives = 205/574 (35%), Gaps = 71/574 (12%) Query: 3 SNDYTQQATQSYGAYPT-QPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ 60 S+ Y +Q + S+ + Q G G Q S YGQ S SG S S DT G G S + Q Sbjct: 176 SSSYGEQNSDSHQSSGRGQCGSGSGQ--SPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQ 233 Query: 61 -----SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Q++GY + G+ S G S+S QSS G++ + SS+ G +GS Sbjct: 234 HKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGER-----HRSSSGSSSSYGQHGS 288 Query: 116 SSQSSSYGQPQSGSYSQQ-PSY------GGQQQSYGQQ---QSYNPPQGY-----GQQNQ 160 S+ S G + GS S+Q PS+ G S+GQ SY+ +G+ GQ + Sbjct: 289 GSRQS-LGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSG 347 Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG-----SGGYGQQDRGG 215 + G G G +G SS G G G SG G S YGQ + Sbjct: 348 FGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS 407 Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGS-- 273 R G G G G S G+ RG G G+ G G+ G + GP GS Sbjct: 408 RHSSGRGQHSSGSG-----QSPGHGQRGSGSGQSPSSGQHGTGFGR-SSSSGPYVSGSGY 461 Query: 274 -----RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDR 328 H+S ++S T G G + + + G ++ G + + Sbjct: 462 SSGFGHHESSSEHSSGYTQHGSGSGHS---SGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518 Query: 329 ETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGR 388 + G ++ + + G+ SG+ S+ R G G Sbjct: 519 QHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGS 578 Query: 389 GGPMGRG----------GYGGGGSGGG-----GRGGFPSGGGGGGGQQRAGDWKCPNPTC 433 G G G GYG GS G G+ G SG GQ A + + Sbjct: 579 GHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQ 638 Query: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMG--GNYGDDRRGGRGGYDRGGYRGRGGDR 491 S + Q + P G GS G +YG G G + G Sbjct: 639 HGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQS 698 Query: 492 GGFRGGRGGGDRGGF---GPGKMDSRGEHRQDRR 522 GF G G G+ G G S G + R Sbjct: 699 SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSR 732 Score = 114 bits (286), Expect = 2e-25 Identities = 136/514 (26%), Positives = 187/514 (36%), Gaps = 93/514 (18%) Query: 25 YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG-YGTQSTPQGYGSTGGYGS 83 YS QSS YG+Q+ S S +SG GQ S GQS N G +G+ S T G GS Sbjct: 172 YSGQSSS-YGEQN----SDSHQSSGRGQCGSGS-GQSPNYGQHGSGSGQSSSNDTHGSGS 225 Query: 84 SQSS-----QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGG 138 QSS +SS GQ S Y +G SS G +GS S SS G+ S SY G Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY-G 284 Query: 139 QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG--------GGGGNYGQDQSSMSSGGGS 190 Q S +Q + QG G + + G G G G G +Y + SG G Sbjct: 285 QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQ 344 Query: 191 GGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250 G+G Q +SG G S GY + G G G++ S G + G G+ Sbjct: 345 TSGFG-QHESGSGQSSGYSKH---------------GSGSGHSSSQGQH---GSTSGQAS 385 Query: 251 RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGI 310 G GS + + G + SRH S + + + G G+ Sbjct: 386 SSGQHGSSSRQSSSY-GQHESASRHSSGRGQHSSGSGQSPGHGQR--------------- 429 Query: 311 IKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT 370 +GQ G+ F S+ G SG+ F Sbjct: 430 ---GSGSGQ-----------SPSSGQHGTGFGRSSSS--------GPYVSGSGYSSGFGH 467 Query: 371 RRADFNRGGGNGRGGRGRGGPMGRGGYG--GGGSGGGGRGGFPSGGGGGGGQQRAGDWKC 428 + G + G G G G G +G G S G R G +G GQ +G Sbjct: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSG---- 523 Query: 429 PNPTCENMNFSWRNECNQCKAPKPD----GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGY 484 + +++ S R+ ++P P G S+ YG R RG Y+ G Sbjct: 524 ---SRQSLGHS-RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579 Query: 485 RGRGGDRGGFRGGRGGG-DRGGFGPGKMDSRGEH 517 G R G+ G + G G + G+H Sbjct: 580 HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQH 613 Score = 110 bits (274), Expect = 4e-24 Identities = 141/530 (26%), Positives = 193/530 (36%), Gaps = 76/530 (14%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQS-SYS----SYGQSQNTGYGTQSTPQGYGSTGG 80 S+QS S SG+S S G G S SYS G Q +G+G + G G + G Sbjct: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHES--GSGQSSG 360 Query: 81 Y---GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSS-QSSSYGQPQSGSYSQQPSY 136 Y GS SS GQ S G +S+SG +GSSS QSSSYGQ +S S + S Sbjct: 361 YSKHGSGSGHSSSQGQHGSTSGQ------ASSSGQHGSSSRQSSSYGQHESAS---RHSS 411 Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196 G Q S G QS G+GQ+ + S G G G SG G G+G+ Sbjct: 412 GRGQHSSGSGQS----PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGH 467 Query: 197 QDQSGGGGSG----GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRG 252 + S SG G G G G+ GS G G S+G G+ G G R Sbjct: 468 HESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGS-GSRQ 526 Query: 253 GMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVT---IESVADYFKQIG 309 +G S R G P RH+S S + G G + + ES + + +G Sbjct: 527 SLGHS-RHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG 585 Query: 310 IIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFA 369 + + +G+ G S+ G+ S + S Sbjct: 586 ---------------HQESRSGQSSGYGQHGSSSGHSST------HGQHGSTSGQSSSCG 624 Query: 370 TRRADFNRGGGNGRGGRG--RGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGD-W 426 A + +G+ G G + G+ G G G S GR G G GQ +G W Sbjct: 625 QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGW 684 Query: 427 KCPN-----PTCENMNFSWRNECNQCKAPKPDGPGGGPG------GSHMGGNYGDDRRGG 475 N + ++ F ++ Q G G GS G + ++ G Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGS 744 Query: 476 RGGYDRG-GYRGRGGDRGGFRGGRGGGD-------RGGFGPGKMDSRGEH 517 G G G G + G +G G R G G S G+H Sbjct: 745 SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794 Score = 110 bits (274), Expect = 4e-24 Identities = 141/556 (25%), Positives = 191/556 (34%), Gaps = 86/556 (15%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQ------STDTSGYGQ----SSYSSYGQSQNTGYGTQST 71 G G+S Q SYS YS+ S TSG+GQ S SS +G G S+ Sbjct: 315 GSGHSSSHGQHGSGSSYS-YSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSS 373 Query: 72 PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS----SSQSSSYGQPQS 127 +GST G SS S +QSS YGQ + S S G S QS +GQ S Sbjct: 374 QGQHGSTSGQASSSGQHGSSSRQSS--SYGQHESASRHSSGRGQHSSGSGQSPGHGQRGS 431 Query: 128 GSYSQQPSYGGQQQSYGQQQSYNP-------PQGYGQQNQYNSSSGG------GGGGGGG 174 GS Q PS G +G+ S P G+G + S G G G G Sbjct: 432 GS-GQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSG 490 Query: 175 GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234 +S SS G G S G S YGQ G R G G G G + Sbjct: 491 HGQHGSRSGQSSRGERQG-------SSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543 Query: 235 SSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGE 294 S G +E R G G G G + GP + GS H S + ++ + G G+ Sbjct: 544 SRGRHESGSRQSSSYGPHGYG----SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ 599 Query: 295 NVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWF 354 + G T+ + G + + G G+++ + + + Sbjct: 600 ---------HGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRY- 649 Query: 355 DGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYG---------GGGSGGG 405 G++ SG+ S +DF G+ G G G G +G G SG G Sbjct: 650 -GQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSG 708 Query: 406 GRGGFPSGGGG---GGGQQRAGDWKCPNPTCENMNFS--WRNECNQCKAPKPDGPGGGPG 460 G+ G G G ++ G + E S + Q + G G Sbjct: 709 QSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQ 768 Query: 461 GSHMGGNYGDDRRGGRGGYDR---------------GGYRGRGGDRGGFRGGRGGGDRG- 504 GS G + R G G+ G Y G GF G +G Sbjct: 769 GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGY 828 Query: 505 ---GFGPGKMDSRGEH 517 G G S+G H Sbjct: 829 SQHGSASGHFSSQGRH 844 Score = 94.7 bits (234), Expect = 2e-19 Identities = 95/307 (30%), Positives = 127/307 (41%), Gaps = 48/307 (15%) Query: 3 SNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ-SYSGYSQST--------DTSGYGQ- 52 S+ Y +Q + S G P +G + S YG+ S SG S S+ ++SG+G Sbjct: 2522 SSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 2580 Query: 53 -------SSYSSYGQSQ--NTGYGTQSTPQGYGSTGG-YGSSQSSQSSYGQQSS----YP 98 SSYS +G ++GYG + G S G +GSS S S YGQ S Sbjct: 2581 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 2640 Query: 99 GYGQQPAPSSTS---GSYGSS-SQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQ- 153 G+G+Q + S S G +GS SSS+GQ SGS + S G + G + + Sbjct: 2641 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS-GRSSSRGPYESRLGHSSVFGQHES 2699 Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-----GY 208 G G + Y+ G G G +G S+ G G G GSG GY Sbjct: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 2759 Query: 209 GQQDRGG-----RGRGGSGGGGGGGGGGYNRSSG---GYEPRGRGGGRGGRGGMGGSDRG 260 G+ G GR GSG G G + SG GY G G G+ G +G Sbjct: 2760 GRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYC----KG 2815 Query: 261 GFNKFGG 267 G N GG Sbjct: 2816 GSNHDGG 2822 Score = 92.4 bits (228), Expect = 9e-19 Identities = 124/483 (25%), Positives = 170/483 (35%), Gaps = 69/483 (14%) Query: 54 SYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY-GQQSSYPGYGQQPAPSSTSGS 112 S+SS+ +N Y T S Q + GQ +SY G SS+ G Sbjct: 128 SHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQ------SSSYGE 181 Query: 113 YGSSS-QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG 171 S S QSS GQ SGS GQ +YGQ S G GQ SSS G Sbjct: 182 QNSDSHQSSGRGQCGSGS--------GQSPNYGQHGS-----GSGQ-----SSSNDTHGS 223 Query: 172 GGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQ-------DRGGRGRGGSGGG 224 G G + G Q SSG SG +Q SG G S GYGQ RG R R SG Sbjct: 224 GSGQSSGFSQHKSSSGQSSGY---SQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSS 280 Query: 225 GG-GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283 G G +R S G+ +G G + GS G + G GS + + + + Sbjct: 281 SSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSG-SGHSSSHGQHGSGSSYSYSRGHYE 339 Query: 284 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 343 + + G G++ + + + K G + + + G G+A+ S Sbjct: 340 SGSGQTSGFGQHESGSGQSSGY---------SKHGSGSGHSSSQGQHGSTSGQASSSGQH 390 Query: 344 PPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSG 403 S++ + + G+ S + + + G+G+ G G G G +G G Sbjct: 391 GSSSRQSSSY--GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGR 448 Query: 404 GGGRGGFPSGGG--GGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGG 461 G + SG G G G + +E + G G G Sbjct: 449 SSSSGPYVSGSGYSSGFGHHESS-----------------SEHSSGYTQHGSGSGHSSGH 491 Query: 462 SHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG-GFGPGKMDSRGEHRQD 520 G G RG R G G G G R G G G G SRG H Sbjct: 492 GQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESG 551 Query: 521 RRE 523 R+ Sbjct: 552 SRQ 554 Score = 90.1 bits (222), Expect = 4e-18 Identities = 86/267 (32%), Positives = 107/267 (40%), Gaps = 38/267 (14%) Query: 11 TQSYGAYPTQPGQG--YSQQSS-----QPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQS- 61 + +G + + GQ YSQ S YGQ S SG S + G S S YGQ Sbjct: 2574 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG 2633 Query: 62 ----QNTGYGTQSTPQGYG-STGGYGSSQSSQSSYGQQSSYPGYGQQPAP-------SST 109 Q++G+G Q + G S G +GS SS+GQ S G P SS Sbjct: 2634 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSV 2693 Query: 110 SGSYGSSS-QSSSYGQPQSGS-----YSQQPSYGGQQQSYGQQ-QSYNPPQGYGQQNQYN 162 G + S S SS+Y Q SGS Q S GQ ++ Q+ S YG + + Sbjct: 2694 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS 2753 Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ------QDRGGR 216 S S G G G G SG G YG Q SG G S GY Q QD Sbjct: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYG-QHGSGSGQSSGYSQHGSGSGQDGYSY 2812 Query: 217 GRGGSGGGGGGGGG---GYNRSSGGYE 240 +GGS GG G + S+ YE Sbjct: 2813 CKGGSNHDGGSSGSYFLSFPSSTSPYE 2839 Score = 50.1 bits (118), Expect = 5e-06 Identities = 47/140 (33%), Positives = 56/140 (40%), Gaps = 14/140 (10%) Query: 19 TQPGQGYSQQSSQPYGQQ-SYSGYSQSTDTSGYGQSSYSSYGQ-----SQNTGYGTQSTP 72 +Q G G SQ GQ S SG S + D G SSYG SQ++GYG Sbjct: 2708 SQHGSGSGHFCSQ--GQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAG 2765 Query: 73 QGYG-STGGYGSSQSSQSSYGQQSS----YPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS 127 G S G +GS SSYGQ S GY Q + S G Y S++ S Sbjct: 2766 SGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG-YSYCKGGSNHDGGSS 2824 Query: 128 GSYSQQPSYGGQQQSYGQQQ 147 GSY Y Q+Q Sbjct: 2825 GSYFLSFPSSTSPYEYVQEQ 2844 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 101 bits (252), Expect = 1e-21 Identities = 74/197 (37%), Positives = 87/197 (44%), Gaps = 39/197 (19%) Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ 160 GQ+ SS +G G + S GSY + S GG SYG Sbjct: 461 GQEDFESSGAGKIGLGGRGGS-----GGSYGRG-SRGGSGGSYG---------------- 498 Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGG 220 GGG GGG GG G S GGSGG YG SGGG GGYG GG G Sbjct: 499 -----GGGSGGGYGGGSG-------SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGS 546 Query: 221 SGGGGGGGGGGY--NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSE 278 GG GG GG Y SGG G GGG G RGG GGS GG + FGG + G + Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS-HGGGSGFGG--ESGGSYGGG 603 Query: 279 QDNSDNNTIFVQGLGEN 295 ++ S + + G G++ Sbjct: 604 EEASGSGGGYGGGSGKS 620 Score = 99.0 bits (245), Expect = 1e-20 Identities = 57/124 (45%), Positives = 63/124 (50%), Gaps = 14/124 (11%) Query: 156 GQQNQYNSSSGG----GGGGGGGGNYGQDQSSMSSG----GGSGGGYGNQDQSGGGGSGG 207 G Q + SS G GG GG GG+YG+ S G GGSGGGYG S GG G Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519 Query: 208 YGQQDRGGRGRGGSGGGG--GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265 YG GG G GG GGG GG GGG++ SGG G GG GG G GG GG+ Sbjct: 520 YG----GGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG 575 Query: 266 GGPR 269 G R Sbjct: 576 SGSR 579 Score = 97.4 bits (241), Expect = 3e-20 Identities = 72/176 (40%), Positives = 76/176 (43%), Gaps = 31/176 (17%) Query: 74 GYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133 G G GG G S S G SY G G SGS G S SYG GS S Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSG--GSYG---GGSGSGG 528 Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193 S GG G G ++ SGGG GG GGNYG SGGGSGGG Sbjct: 529 GSGGGY--------------GGGSGGGHSGGSGGGHSGGSGGNYG---GGSGSGGGSGGG 571 Query: 194 YGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG 249 YG S GG G +G GG G GG GG GGG + S GGY GGG G Sbjct: 572 YGGGSGSRGGSGGSHG----GGSGFGGESGGSYGGGEEASGSGGGY-----GGGSG 618 Score = 86.3 bits (212), Expect = 6e-17 Identities = 57/133 (42%), Positives = 62/133 (46%), Gaps = 25/133 (18%) Query: 159 NQYNSSSGGGGGG--GGGGNYGQDQSSMSSGGGSGG--------GYGNQDQS-------- 200 + Y S SGGGGGG G GG+ S SS GG GG GYG Sbjct: 8 SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67 Query: 201 ------GGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM 254 GGG GG+ GG GGS G GG GGGY+ SSGG+ GG GG GG Sbjct: 68 SFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYS-SSGGFGGGFGGGSGGGFGGG 126 Query: 255 GGSDRGGFNKFGG 267 GS GGF FGG Sbjct: 127 YGSGFGGFGGFGG 139 Score = 86.3 bits (212), Expect = 6e-17 Identities = 67/159 (42%), Positives = 75/159 (47%), Gaps = 27/159 (16%) Query: 74 GYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133 G G GG GS S +SSY + SS G G SS+SG G SS+ G S YS Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS-- 72 Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGG-GGGGGGNYGQDQSSMSSGGGSGG 192 YGG G +++SS GGG GGG G G SS GG GG Sbjct: 73 --YGG-----------------GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGG 113 Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231 G+G SGGG GGYG G G GG GGG GGG GG Sbjct: 114 GFGG--GSGGGFGGGYGS---GFGGFGGFGGGAGGGDGG 147 Score = 84.3 bits (207), Expect = 2e-16 Identities = 60/149 (40%), Positives = 69/149 (46%), Gaps = 17/149 (11%) Query: 119 SSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGG------G 172 SSSY G GG +S ++ G G +++SSSG GGG G Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRS--SYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64 Query: 173 GGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGY 232 GGG++G S GGGSGGG+ GG G G G G G SGG GGG GGG Sbjct: 65 GGGSFGY-----SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG- 118 Query: 233 NRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 SGG G G G GG GG GG GG Sbjct: 119 ---SGGGFGGGYGSGFGGFGGFGGGAGGG 144 Score = 82.8 bits (203), Expect = 7e-16 Identities = 55/136 (40%), Positives = 63/136 (46%), Gaps = 19/136 (13%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG--FPSGGGGGGGQQRAGDWKCPNPTC 433 +R GG G GG G GG + R Y S GGG GG F S G GGG R C Sbjct: 12 SRSGGGGGGGLGSGGSI-RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV----CGRGGG 66 Query: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493 + +S+ G GGG S +GG +G RG GG GGY GG GG Sbjct: 67 GSFGYSYGG-----------GSGGGFSASSLGGGFGGGSRGF-GGASGGGYSSSGGFGGG 114 Query: 494 FRGGRGGGDRGGFGPG 509 F GG GGG GG+G G Sbjct: 115 FGGGSGGGFGGGYGSG 130 Score = 79.0 bits (193), Expect = 1e-14 Identities = 55/132 (41%), Positives = 57/132 (43%), Gaps = 17/132 (12%) Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 RGG G GRG G G G YGGGGSGGG GG S GG GG Sbjct: 478 RGGSGGSYGRGSRGGSG-GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG----------- 525 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRG-GRGGYDRGGYRGRGGDRGGFR 495 S G GG GG H GG+ G+ G G GG GGY G G RGG Sbjct: 526 --SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSG 583 Query: 496 GGRGGGDRGGFG 507 G GGG GFG Sbjct: 584 GSHGGG--SGFG 593 Score = 73.6 bits (179), Expect = 4e-13 Identities = 53/135 (39%), Positives = 59/135 (43%), Gaps = 20/135 (14%) Query: 378 GGGNGRG-GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 GGG+G G G G G G GG GGGSG GG G GGG GGG + N Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNY 558 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496 G GGG GG + GG+ RGG GG GG G GG+ GG G Sbjct: 559 GGG-------------SGSGGGSGGGYGGGS---GSRGGSGG-SHGGGSGFGGESGGSYG 601 Query: 497 G--RGGGDRGGFGPG 509 G G GG+G G Sbjct: 602 GGEEASGSGGGYGGG 616 Score = 68.6 bits (166), Expect = 1e-11 Identities = 61/174 (35%), Positives = 72/174 (41%), Gaps = 21/174 (12%) Query: 51 GQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTS 110 GQ + S G + G G + G G + G GS S SYG S GYG S Sbjct: 461 GQEDFESSGAGK-IGLGGRG---GSGGSYGRGSRGGSGGSYGGGGSGGGYGG--GSGSRG 514 Query: 111 GSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG 170 GS GS S G G Y S GG G S YG + SGGG G Sbjct: 515 GSGGSYGGGSGSGGGSGGGYGGG-SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573 Query: 171 GGG------GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR 218 GG GG++G GG SGG YG +++ G G GGYG GG G+ Sbjct: 574 GGSGSRGGSGGSHG---GGSGFGGESGGSYGGGEEASGSG-GGYG----GGSGK 619 Score = 65.9 bits (159), Expect = 9e-11 Identities = 53/160 (33%), Positives = 59/160 (36%), Gaps = 51/160 (31%) Query: 360 SGNPIKVSFATRRADFNRGGGNGRGGR---------------GRGGPMGRGGYGGGGSGG 404 SG I+ S++ F+ GG G GGR GRGG G GY GG G Sbjct: 24 SGGSIRSSYSR----FSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG-GSFGYSYGGGSG 78 Query: 405 GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHM 464 GG GGG GGG + G G GG Sbjct: 79 GGFSASSLGGGFGGGSRGFG-------------------------------GASGGGYSS 107 Query: 465 GGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG 504 G +G GG GG GGY G GGF GG GGGD G Sbjct: 108 SGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGG 147 Score = 64.3 bits (155), Expect = 3e-10 Identities = 58/185 (31%), Positives = 68/185 (36%), Gaps = 41/185 (22%) Query: 22 GQGYSQQSSQPYGQQSYSG----YSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGS 77 G G S YG+ S G Y GYG S S G + G G+ S G GS Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS---GGGS 530 Query: 78 TGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137 GGYG S G + G + G+YG S S G Sbjct: 531 GGGYGGGSGGGHSGGSGGGHSG--------GSGGNYGGGSGSG----------------G 566 Query: 138 GQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG--GGNYGQDQSSMSSGGGSGGGYG 195 G YG G G + S GGG G GG GG+YG + + SGGG GGG G Sbjct: 567 GSGGGYG--------GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618 Query: 196 NQDQS 200 S Sbjct: 619 KSSHS 623 Score = 61.2 bits (147), Expect = 2e-09 Identities = 48/131 (36%), Positives = 50/131 (38%), Gaps = 44/131 (33%) Query: 385 GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNEC 444 G G+ G GRGG GG G G RGG SGG GGG Sbjct: 469 GAGKIGLGGRGG-SGGSYGRGSRGG--SGGSYGGG------------------------- 500 Query: 445 NQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRG 504 G GGG GG G RGG GG GG GG GG+ GG GGG G Sbjct: 501 ---------GSGGGYGG-------GSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544 Query: 505 GFGPGKMDSRG 515 G G G G Sbjct: 545 GSGGGHSGGSG 555 Score = 52.0 bits (123), Expect = 1e-06 Identities = 46/164 (28%), Positives = 65/164 (39%), Gaps = 16/164 (9%) Query: 27 QQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQS 86 +Q S Y +S G + G +SSYS + S G G + + S+ GYG S Sbjct: 4 RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGR-----FSSSSGYGGGSS 58 Query: 87 SQSSYGQQSSYP-----GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQ 141 G S+ G G + SS G +G S+ +G G YS +GG Sbjct: 59 RVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRG--FGGASGGGYSSSGGFGG--- 113 Query: 142 SYGQQQSYNPPQGYGQQ-NQYNSSSGGGGGGGGGGNYGQDQSSM 184 +G GYG + GG GGG GG ++S+M Sbjct: 114 GFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTM 157 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/53 (50%), Positives = 31/53 (58%), Gaps = 5/53 (9%) Query: 376 NRGGGNGRGGRGRGGPMG----RGGYGGGGSGGGGRGGFPSGGGGGGGQQRAG 424 N GGG+G GG GG G RGG GG GG G GG SGG GGG++ +G Sbjct: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGG-ESGGSYGGGEEASG 608 Score = 43.5 bits (101), Expect = 5e-04 Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 8/111 (7%) Query: 13 SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST- 71 SYG G G S YG S G+S + G+ S +YG +G G+ Sbjct: 519 SYGG-----GSGSGGGSGGGYGGGSGGGHSGGSG-GGHSGGSGGNYGGGSGSGGGSGGGY 572 Query: 72 PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY 122 G GS GG G S S +G +S YG S + G YG S SS+ Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESG-GSYGGGEEASGSGGGYGGGSGKSSH 622 Score = 43.1 bits (100), Expect = 6e-04 Identities = 23/48 (47%), Positives = 27/48 (56%), Gaps = 2/48 (4%) Query: 378 GGGNGRGGRGRGGPMGRGGYGG--GGSGGGGRGGFPSGGGGGGGQQRA 423 GGG+G G G G G+GG GGS GGG SGGG GGG ++ Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/65 (44%), Positives = 29/65 (44%), Gaps = 9/65 (13%) Query: 218 RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR----GGMGGSD-----RGGFNKFGGP 268 R G GGGGG G GG RSS GGG GGR G GG RGG FG Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72 Query: 269 RDQGS 273 GS Sbjct: 73 YGGGS 77 Score = 36.2 bits (82), Expect = 0.076 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 14/72 (19%) Query: 445 NQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGG-YDRGGYRGRGGDRGGFRGGRGGGDR 503 N + + D G G +GG RGG GG Y RG G GG GG GG Sbjct: 456 NLLEGGQEDFESSGAGKIGLGG------RGGSGGSYGRGSRGGSGGSYGG------GGSG 503 Query: 504 GGFGPGKMDSRG 515 GG+G G SRG Sbjct: 504 GGYGGGS-GSRG 514 Score = 35.4 bits (80), Expect = 0.13 Identities = 47/183 (25%), Positives = 58/183 (31%), Gaps = 67/183 (36%) Query: 13 SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTP 72 SY + + G G + S G Y G S G G S SYG G+ S Sbjct: 31 SYSRFSSSGGGGGGGRFSSSSG---YGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLG 87 Query: 73 QGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132 G+G GG S +G +S G YS Sbjct: 88 GGFG--GG-----------------------------SRGFGGAS---------GGGYSS 107 Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192 +GG G+G SGGG GGG G +G GGG+GG Sbjct: 108 SGGFGG---------------GFG------GGSGGGFGGGYGSGFG---GFGGFGGGAGG 143 Query: 193 GYG 195 G G Sbjct: 144 GDG 146 Score = 34.7 bits (78), Expect = 0.22 Identities = 28/85 (32%), Positives = 30/85 (35%), Gaps = 18/85 (21%) Query: 444 CNQCKAPKPDGPGGGPGG---------------SHMGGNYGDDRRGGRGGYDRGGYR--G 486 C Q + GGG GG S GG G R GY G R G Sbjct: 3 CRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCG 62 Query: 487 RGGDRGGFRGGRGGGDRGGFGPGKM 511 RGG G F GGG GGF + Sbjct: 63 RGGG-GSFGYSYGGGSGGGFSASSL 86 Score = 33.5 bits (75), Expect = 0.49 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 8/42 (19%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGG 417 + GGG+G GG G YGGG G GG+ GGG G Sbjct: 585 SHGGGSGFGGE------SGGSYGGGEEASGSGGGY--GGGSG 618 >gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sapiens] Length = 378 Score = 101 bits (251), Expect = 2e-21 Identities = 89/272 (32%), Positives = 121/272 (44%), Gaps = 41/272 (15%) Query: 268 PRDQGSRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325 P+ SR DS + + IFV G+ E+ ++ DYF++ G I+T I + Sbjct: 107 PKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIET--------IEVM 158 Query: 326 TDRETGKLKGEATVSFDDPPSA-KAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGN-GR 383 DR++GK +G A V+FDD + K + + +G+ +V A + + G GR Sbjct: 159 EDRQSGKKRGFAFVTFDDHDTVDKIVVQKYH--TINGHNCEVKKALSKQEMQSAGSQRGR 216 Query: 384 GGRGRGGPMGRGGYGGGGSGG-------GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 GG G G MGRGG GGG G GGRGG+ GGGG G GD + Sbjct: 217 GG-GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGG 275 Query: 437 NFSWRNECNQCKAPKPDGP-----------GGGPGGSHMGGNYGDDRRGGRGGY-DRGGY 484 N+ + GP GGG G + GGN+G GG G Y D G Y Sbjct: 276 NYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNY 335 Query: 485 RGR-----GGDRGGFRGGRGGGD--RGGFGPG 509 G+ G +GG GGR G GG+G G Sbjct: 336 SGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSG 367 Score = 84.0 bits (206), Expect = 3e-16 Identities = 58/154 (37%), Positives = 71/154 (46%), Gaps = 20/154 (12%) Query: 135 SYGGQQQSYGQQQSYNPPQGYG-----QQNQYNSSSGGGGG-GGGGGNYGQDQSSMSSGG 188 ++GG ++G+ ++ GYG + Y GG G GG GGNYG S GG Sbjct: 229 NFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGG 288 Query: 189 GSGGGYGNQDQSGG-GGSGGYGQQDRGGRGRGGSGGGGGGGGGGYN-------RSSGGYE 240 GGG G +Q GG GG GGY + G G GGG GGGG YN + Y Sbjct: 289 YGGGGPGYGNQGGGYGGGGGYDGYNEG----GNFGGGNYGGGGNYNDFGNYSGQQQSNYG 344 Query: 241 PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR 274 P +GG GGR G GG+ GG GSR Sbjct: 345 PM-KGGSFGGRSS-GSPYGGGYGSGGGSGGYGSR 376 Score = 81.3 bits (199), Expect = 2e-15 Identities = 53/138 (38%), Positives = 61/138 (44%), Gaps = 12/138 (8%) Query: 153 QGYGQQNQYNSSSG-----GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207 Q G Q SG GG GGGGGN+G+ + GG GGG G++ GGG G Sbjct: 208 QSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGY 267 Query: 208 YGQQDRGGRGRGGSG----GGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFN 263 G GG GG G GG GGGG GY GGY G GGG G G G + Sbjct: 268 NGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGY---GGGGGYDGYNEGGNFGGGNYG 324 Query: 264 KFGGPRDQGSRHDSEQDN 281 G D G+ +Q N Sbjct: 325 GGGNYNDFGNYSGQQQSN 342 Score = 76.3 bits (186), Expect = 7e-14 Identities = 50/120 (41%), Positives = 60/120 (50%), Gaps = 12/120 (10%) Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG--GSGGGYGNQDQSGGGGSGGYGQQDRG 214 +Q ++ S G GGG G G+ + GG G GG +G + GGGG G G G Sbjct: 204 KQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGG 263 Query: 215 GRGRGGSGGGGG--GGGGGYNRSSGGYEPRG-----RGGGRGGRGGMGGSDRGGFNKFGG 267 G G GG GG GGG GY+ S GGY G +GGG GG GG G + GG FGG Sbjct: 264 DGGYNGFGGDGGNYGGGPGYS-SRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGG--NFGG 320 Score = 73.9 bits (180), Expect = 3e-13 Identities = 58/188 (30%), Positives = 77/188 (40%), Gaps = 29/188 (15%) Query: 57 SYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSS 116 S G + G G+ + G+ GG G + ++G + Y G G + GSYG Sbjct: 209 SAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGG-----GGSRGSYGGG 263 Query: 117 SQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN 176 G Y+ +GG +YG Y+ GYG + GGG GGGGG + Sbjct: 264 D----------GGYN---GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYD 310 Query: 177 YGQDQSSMSSGGGSGGG--------YGNQDQSGGGG--SGGYGQQDRGGRGRGGSGGGGG 226 G ++ GG GGG Y Q QS G G +G + G GG G GGG Sbjct: 311 -GYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGG 369 Query: 227 GGGGGYNR 234 GG G R Sbjct: 370 SGGYGSRR 377 Score = 73.9 bits (180), Expect = 3e-13 Identities = 65/185 (35%), Positives = 79/185 (42%), Gaps = 45/185 (24%) Query: 49 GYGQSSYSSYGQSQNTGYGTQSTPQG--YGSTGGY-GSSQSSQSSY-GQQSSYPGYGQQP 104 G G S + G+ N G G + +G +G GGY G S+ SY G Y G+G Sbjct: 215 GRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFG--- 271 Query: 105 APSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSS 164 G+YG SS G G P YG Q YG Y+ GY + + Sbjct: 272 ---GDGGNYGGGPGYSSRGGYGGGG----PGYGNQGGGYGGGGGYD---GYNEGGNF--- 318 Query: 165 SGGGGGGGGGGNY-------GQDQSS-----------MSSGGGSGGGYGNQDQSGGGGSG 206 GGG GGGGNY GQ QS+ SSG GGGYG+ GGGSG Sbjct: 319 --GGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGS-----GGGSG 371 Query: 207 GYGQQ 211 GYG + Sbjct: 372 GYGSR 376 Score = 69.7 bits (169), Expect = 6e-12 Identities = 44/92 (47%), Positives = 46/92 (50%), Gaps = 4/92 (4%) Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGG--GGYNRSS 236 Q+ S S G GGG GN GG GG G RGG G G GGGGGG G Y Sbjct: 205 QEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGD 264 Query: 237 GGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGP 268 GGY G GG G GG G S RGG+ GGP Sbjct: 265 GGYNGFGGDGGNYG-GGPGYSSRGGYGG-GGP 294 Score = 54.7 bits (130), Expect = 2e-07 Identities = 49/170 (28%), Positives = 67/170 (39%), Gaps = 41/170 (24%) Query: 13 SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDT--SGYGQSSYSSYGQSQNTGYGTQS 70 ++G G G + S G Y+G+ G G SS YG GYG Q Sbjct: 242 NFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGG-GPGYGNQG 300 Query: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSY 130 GYG GGY Y + ++ G G+YG G+Y Sbjct: 301 G--GYGGGGGY-------DGYNEGGNFGG-----------GNYGG-----------GGNY 329 Query: 131 SQQPSYGGQQQSYGQQQSYNPPQG--YGQQNQYNSSSGGGGGGGGGGNYG 178 + +Y GQQQS +Y P +G +G ++ + GG G GGG G YG Sbjct: 330 NDFGNYSGQQQS-----NYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYG 374 Score = 50.4 bits (119), Expect = 4e-06 Identities = 54/204 (26%), Positives = 70/204 (34%), Gaps = 48/204 (23%) Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR----GGFNKFGGPRDQ 271 RGRGG G G GG + G + G GGRGG GG GG R GG + G Sbjct: 214 RGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGD 273 Query: 272 GSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETG 331 G + S G G Y ++ G Sbjct: 274 GGNYGGGPGYSSRGGYGGGGPG-------------------------------YGNQGGG 302 Query: 332 KLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFAT----RRADFNRGGGNGRGGRG 387 G +++ + F G + G F +++++ G GGR Sbjct: 303 YGGGGGYDGYNEGGN-------FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRS 355 Query: 388 RGGPMGRGGYG-GGGSGGGGRGGF 410 G P G GGYG GGGSGG G F Sbjct: 356 SGSPYG-GGYGSGGGSGGYGSRRF 378 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/47 (53%), Positives = 29/47 (61%), Gaps = 5/47 (10%) Query: 475 GRGGYDRGGYRGRGGDRGGFRG--GRGG--GDRGGFGPGKMDSRGEH 517 GRGG G + GRGG+ GG G GRGG G RGG+G G SRG + Sbjct: 215 GRGG-GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSY 260 Score = 40.0 bits (92), Expect = 0.005 Identities = 27/69 (39%), Positives = 29/69 (42%), Gaps = 28/69 (40%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGS-------------------GG--GGR-------GG 409 GGG G G GG G G YGGGG+ GG GGR GG Sbjct: 304 GGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGG 363 Query: 410 FPSGGGGGG 418 + SGGG GG Sbjct: 364 YGSGGGSGG 372 Score = 35.8 bits (81), Expect = 0.099 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 24 GYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGS 83 GY++ + +G +Y G D Y S+YG + +G +S+ YG GGYGS Sbjct: 311 GYNEGGN--FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYG--GGYGS 366 Query: 84 SQSSQSSYGQQ 94 S YG + Sbjct: 367 GGGS-GGYGSR 376 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 98.2 bits (243), Expect = 2e-20 Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 15/158 (9%) Query: 271 QGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330 QG R + + T+FV+GL E+ T E++ + F G + TDRET Sbjct: 558 QGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD-----------GSVRARIVTDRET 606 Query: 331 GKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGG-GNGRGGRG-- 387 G KG V F+ AKAA + + E GN + + +A + + GG G GRGG G Sbjct: 607 GSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGR 666 Query: 388 RGGPMGRGGYGGGGSGG-GGRGGFPSGGGGGGGQQRAG 424 GG GRGG+GG G GG GGRGGF G GGGG + G Sbjct: 667 GGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQG 704 Score = 58.2 bits (139), Expect = 2e-08 Identities = 62/231 (26%), Positives = 87/231 (37%), Gaps = 25/231 (10%) Query: 281 NSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVS 340 + ++ T+ + L + T E++ + F++ IK + + GK KG A + Sbjct: 482 SGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQN------------QNGKSKGYAFIE 529 Query: 341 FDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGG 400 F AK A++ + +E G I++ R N + +G Sbjct: 530 FASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLK 589 Query: 401 GSGGGG--------RGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKP 452 S G R S G G D K E+ PK Sbjct: 590 ESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKG 649 Query: 453 DGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG--GDRGGFRGGRGGG 501 +G GG GG G RGGRGG+ G RGRG G RGGFRGGRGGG Sbjct: 650 EGGFGGRGGGRGGFGGRGGGRGGRGGF---GGRGRGGFGGRGGFRGGRGGG 697 Score = 56.2 bits (134), Expect = 7e-08 Identities = 30/54 (55%), Positives = 31/54 (57%), Gaps = 10/54 (18%) Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPR 269 +G GG GG GGG GG GRGGGRGGRGG GG RGGF GG R Sbjct: 648 KGEGGFGGRGGGRGGF----------GGRGGGRGGRGGFGGRGRGGFGGRGGFR 691 Score = 55.8 bits (133), Expect = 9e-08 Identities = 34/64 (53%), Positives = 38/64 (59%), Gaps = 16/64 (25%) Query: 192 GGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251 GG+G + GGG GG+G RGG GRGG GG GG G GG+ GRGG RGGR Sbjct: 651 GGFGGR----GGGRGGFG--GRGG-GRGGRGGFGGRGRGGFG---------GRGGFRGGR 694 Query: 252 GGMG 255 GG G Sbjct: 695 GGGG 698 Score = 50.1 bits (118), Expect = 5e-06 Identities = 30/63 (47%), Positives = 32/63 (50%), Gaps = 15/63 (23%) Query: 167 GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG 226 GG GG GGG G GG GGG G + GG G GG+G GRGG GG G Sbjct: 651 GGFGGRGGGRGGF--------GGRGGGRGGRGGFGGRGRGGFG-------GRGGFRGGRG 695 Query: 227 GGG 229 GGG Sbjct: 696 GGG 698 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGG 231 G D + GG GG G + GG G G G+ GGRGRGG GG GG GG GG Sbjct: 637 GNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGG 696 Query: 232 YNRSSGGYEPRGR 244 G ++P+G+ Sbjct: 697 ----GGDHKPQGK 705 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/57 (47%), Positives = 32/57 (56%), Gaps = 12/57 (21%) Query: 166 GGGGGGGGGGNYGQDQSSMSSGGGSGG--GYGNQDQSGGGGSGGYGQQDRGGRGRGG 220 G GG GGG G +G GGG GG G+G + + G GG GG+ RGGRG GG Sbjct: 652 GFGGRGGGRGGFG------GRGGGRGGRGGFGGRGRGGFGGRGGF----RGGRGGGG 698 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 96.7 bits (239), Expect = 5e-20 Identities = 59/123 (47%), Positives = 64/123 (52%), Gaps = 11/123 (8%) Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS-GGGYGNQDQSGGGGSGGYGQQD 212 GYG + SSGGG GGG GG+ G SSGGGS GGGYG GG SGG+G Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG-----GGSSSGGHGGSS 526 Query: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272 GG G G SGGGGGG GGG SSGG GGG GG GG G +G Sbjct: 527 SGGYGGGSSGGGGGGYGGG---SSGG--GSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581 Query: 273 SRH 275 R+ Sbjct: 582 PRY 584 Score = 93.2 bits (230), Expect = 5e-19 Identities = 62/143 (43%), Positives = 69/143 (48%), Gaps = 20/143 (13%) Query: 150 NPPQGYGQQNQYNSSSGGGGGGGG--GGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207 N Q Y + SSGGGG GGG GG YG GG SGGG SGGG GG Sbjct: 444 NEIQTYRSLLEGEGSSGGGGRGGGSFGGGYG--------GGSSGGG-----SSGGGHGGG 490 Query: 208 YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGY---EPRGRGGGR--GGRGGMGGSDRGGF 262 +G GG G G SGGG GGG G SSGG+ G GGG GG GG GG GG Sbjct: 491 HGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG 550 Query: 263 NKFGGPRDQGSRHDSEQDNSDNN 285 + GG GS + +S + Sbjct: 551 SSSGGGYGGGSSSGGHKSSSSGS 573 Score = 81.3 bits (199), Expect = 2e-15 Identities = 52/132 (39%), Positives = 54/132 (40%), Gaps = 17/132 (12%) Query: 107 SSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG 166 SS G G S YG SG S +GG G Y S Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGH-------------GGSSGGGYGGGSS 504 Query: 167 GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG 226 GGG GGG YG SS GG S GGYG S GGG GGYG GG G G GGG Sbjct: 505 GGGSSGGG--YGGGSSSGGHGGSSSGGYGG--GSSGGGGGGYGGGSSGGGSSSGGGYGGG 560 Query: 227 GGGGGYNRSSGG 238 GG+ SS G Sbjct: 561 SSSGGHKSSSSG 572 Score = 79.0 bits (193), Expect = 1e-14 Identities = 53/136 (38%), Positives = 58/136 (42%), Gaps = 23/136 (16%) Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSM-------------SSGGGSGGGYGNQDQSG 201 Y Y+SS GGGGGGGG G SS+ SSGG SGG + G Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGG 64 Query: 202 G---GGSGGYGQQD-------RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGR 251 G G SGGYG RG G GG GG GG + G + GGG G Sbjct: 65 GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGG 124 Query: 252 GGMGGSDRGGFNKFGG 267 GG GG GGF GG Sbjct: 125 GGFGGGFGGGFGGDGG 140 Score = 76.3 bits (186), Expect = 7e-14 Identities = 55/142 (38%), Positives = 58/142 (40%), Gaps = 36/142 (25%) Query: 379 GGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF--PSGGGGGGGQQRAGDWKCPNPTCENM 436 GG GRGG GG G G GGG SGGG GG SGGG GGG G Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG------------ 507 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496 GGG GG G +G GG GG GG G GG GG G Sbjct: 508 -----------------SSGGGYGGGSSSGGHGGSSSGGYGGGSSGG--GGGGYGGGSSG 548 Query: 497 GRGGGDRGGFGPGKMDSRGEHR 518 G G GG+G G S G H+ Sbjct: 549 G-GSSSGGGYGGG--SSSGGHK 567 Score = 71.2 bits (173), Expect = 2e-12 Identities = 55/145 (37%), Positives = 57/145 (39%), Gaps = 37/145 (25%) Query: 377 RGGGN---GRGGRGRGGPMGRGGYGGG--GSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431 RGGG+ G GG GG GG+GGG GS GGG GG SGGG GG G Sbjct: 464 RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG------- 516 Query: 432 TCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDR 491 GG GGS GG G GG GGY GG G G Sbjct: 517 ----------------------SSSGGHGGSSSGGYGGGSSGGGGGGYG-GGSSGGGSSS 553 Query: 492 GGFRGGRGGGDRGGFGPGKMDSRGE 516 GG G GG GG S GE Sbjct: 554 GG--GYGGGSSSGGHKSSSSGSVGE 576 Score = 68.9 bits (167), Expect = 1e-11 Identities = 60/188 (31%), Positives = 70/188 (37%), Gaps = 53/188 (28%) Query: 36 QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQS 95 Q+Y + +SG G S+G GYG S+ G S GG+G S G Sbjct: 447 QTYRSLLEGEGSSGGGGRGGGSFGG----GYGGGSSGGG-SSGGGHGGGHGGSSGGGYGG 501 Query: 96 SYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGY 155 G G S+ G YG S S +G SG GY Sbjct: 502 GSSGGG------SSGGGYGGGSSSGGHGGSSSG-------------------------GY 530 Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG 215 G SSGGGGGG GGG+ G G SGGGYG GG SGG+ G Sbjct: 531 G-----GGSSGGGGGGYGGGSSG-------GGSSSGGGYG-----GGSSSGGHKSSSSGS 573 Query: 216 RGRGGSGG 223 G S G Sbjct: 574 VGESSSKG 581 Score = 66.6 bits (161), Expect = 5e-11 Identities = 59/166 (35%), Positives = 69/166 (41%), Gaps = 29/166 (17%) Query: 75 YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQP 134 Y S+ Y SS+S G G SS+ GS G S + GS+S+ Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS---GGSFSRGS 61 Query: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGGGSGG 192 S GG + SSGG GG G GGG++ S S GG GG Sbjct: 62 SGGGC---------------------FGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGG 100 Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGG-GGGGGGGYNRSSG 237 +G S GGGS G G GG G GG GGG GGG GG SG Sbjct: 101 SFGGG--SFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSG 144 Score = 63.2 bits (152), Expect = 6e-10 Identities = 51/155 (32%), Positives = 58/155 (37%), Gaps = 36/155 (23%) Query: 364 IKVSFATRRADFNRGGGNGRGGRGRGGPM-------GRGGYGGGGSGGGGRGGFPSGGGG 416 ++ S + + GGG G GG G GG + +G GGG S GG GG S G Sbjct: 3 VRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62 Query: 417 GGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPG--GGPGGSHMGGNYGDDRRG 474 GGG C G G GG GG G+YG G Sbjct: 63 GGG---------------------------CFGGSSGGYGGLGGFGGGSFRGSYGSSSFG 95 Query: 475 GRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPG 509 G G GG GG GG G GG GGFG G Sbjct: 96 GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 4/79 (5%) Query: 359 FSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGG 418 F G + S+ + + GG G G G GG G G +GGGG GGGG GG GG GG Sbjct: 80 FGGGSFRGSYGSSSFGGSYGGSFGGGSFG-GGSFGGGSFGGGGFGGGGFGGGFGGGFGGD 138 Query: 419 GQQRAGDWKCPNPTCENMN 437 G +G+ K T +N+N Sbjct: 139 GGLLSGNEKV---TMQNLN 154 Score = 50.4 bits (119), Expect = 4e-06 Identities = 52/161 (32%), Positives = 62/161 (38%), Gaps = 41/161 (25%) Query: 378 GGGNGRGGRGR-------------GGPMGRGGYGGG----GSGGGGRGGFPSGGGGGGGQ 420 GGG G GG G GG GG+ GG GS GGG G SGG GG G Sbjct: 20 GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGG 79 Query: 421 QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD 480 G ++ + + +F GG GG GG G G + Sbjct: 80 FGGGSFR---GSYGSSSFG-------------GSYGGSFGGGSFGGG-----SFGGGSFG 118 Query: 481 RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDR 521 GG+ G GG GGF GG GG GG G ++ DR Sbjct: 119 GGGF-GGGGFGGGFGGGFGGD--GGLLSGNEKVTMQNLNDR 156 Score = 47.8 bits (112), Expect = 3e-05 Identities = 36/108 (33%), Positives = 44/108 (40%), Gaps = 5/108 (4%) Query: 34 GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQS----SQS 89 G S G S G+G SS YG + G + G S+GG+G S S S Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGS 534 Query: 90 SYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137 S G Y G G SS+ G YG S S + SGS + S G Sbjct: 535 SGGGGGGYGG-GSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581 Score = 44.3 bits (103), Expect = 3e-04 Identities = 39/101 (38%), Positives = 45/101 (44%), Gaps = 15/101 (14%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSS-YGQSQNTGYGTQSTPQGYGSTGG 80 G G+ S YG S G S GYG S S +G S + GYG GS+GG Sbjct: 488 GGGHGGSSGGGYGGGSSGGGSSG---GGYGGGSSSGGHGGSSSGGYGG-------GSSGG 537 Query: 81 YGSSQSSQSSYGQQSSYPGYGQQPA----PSSTSGSYGSSS 117 G SS G SS GYG + SS+SGS G SS Sbjct: 538 GGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESS 578 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/172 (28%), Positives = 57/172 (33%), Gaps = 78/172 (45%) Query: 33 YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG 92 + +SG S S +SG G +G S GYG GG+G Sbjct: 47 FSSGGFSGGSFSRGSSGGG-----CFGGSSG----------GYGGLGGFGG--------- 82 Query: 93 QQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152 S GSYGSSS SYG G S+GG Sbjct: 83 --------------GSFRGSYGSSSFGGSYGGSFGGG-----SFGG-------------- 109 Query: 153 QGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG 204 + S GGGG GGGG GGG GGG+G G GG Sbjct: 110 ------GSFGGGSFGGGGFGGGG----------FGGGFGGGFG-----GDGG 140 Score = 42.0 bits (97), Expect = 0.001 Identities = 45/152 (29%), Positives = 57/152 (37%), Gaps = 16/152 (10%) Query: 41 YSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYG-STGGYGSSQSSQSSYGQQ---SS 96 YS S G G G + + G G S+GG+ S+ S G S Sbjct: 11 YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70 Query: 97 YPGYGQQPA--PSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154 GYG S GSYGSSS SYG G S+GG G G Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG---------G 121 Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS 186 +G + GGG GG GG G ++ +M + Sbjct: 122 FGGGG-FGGGFGGGFGGDGGLLSGNEKVTMQN 152 Score = 29.3 bits (64), Expect = 9.2 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 6/78 (7%) Query: 14 YGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ 73 YG + G G S G G +SG G SS YG ++G G +S+ Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG-GHKSS-- 569 Query: 74 GYGSTGGYGSSQSSQSSY 91 S+G G S S Y Sbjct: 570 ---SSGSVGESSSKGPRY 584 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 96.7 bits (239), Expect = 5e-20 Identities = 113/361 (31%), Positives = 128/361 (35%), Gaps = 100/361 (27%) Query: 164 SSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGG 223 +SGGGGGGGG SGGG G +G GGGSGG G G G SGG Sbjct: 19 TSGGGGGGGG------------SGGGGCGFFG------GGGSGG----GSSGSGCGYSGG 56 Query: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283 GG GGG SSGG GG GG GG GG G GG G Sbjct: 57 GGYSGGGCGGGSSGG-------GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGG 109 Query: 284 NNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD 343 + F G G + S F G G G + F Sbjct: 110 GSGCFSSGGGGSSGGGSGC--FSSGG---------------------GGSSGGGSGCFSS 146 Query: 344 PPSAKAAIDWFDGKEFSGNPIKV-SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402 G FSG ++ S+ + + GGG+G G GG GY GGGS Sbjct: 147 -----------GGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG-SVCGYSGGGS 194 Query: 403 GGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462 G GG G GG G + +C AP+P GG GG Sbjct: 195 GCGG------GSSGGSGSGYVSSQQVTQTSC---------------APQPSYGGGSSGGG 233 Query: 463 HMGGNYGDDRRGGRGGYD--RGGYRGRGGD----------RGGFRGGRGGGDR-GGFGPG 509 GG+ G GG GG GG G G GG GG GGG GG G G Sbjct: 234 GSGGS-GCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292 Query: 510 K 510 K Sbjct: 293 K 293 Score = 93.2 bits (230), Expect = 5e-19 Identities = 107/332 (32%), Positives = 121/332 (36%), Gaps = 60/332 (18%) Query: 102 QQPAPS------STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGY 155 +QP P TSG G S G G + S GG S G Y+ GY Sbjct: 6 KQPTPQPPVDCVKTSGGGGGGGGSGGGG---CGFFGGGGSGGG---SSGSGCGYSGGGGY 59 Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSM--SSGGGSGGGYGNQDQSGGGGSG----GYG 209 SSGGGGGGG GG G S+ S GGGS GG SGGGGSG G G Sbjct: 60 SGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGG 119 Query: 210 QQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM--GGSDRGGFNKFGG 267 GG G SGGGG GGG SSGG G+ GG+ GGS GG F Sbjct: 120 GSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSS 179 Query: 268 PRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTD 327 GS S G G + S + Y + +T Sbjct: 180 GGGGGSVCGYSGGGS--------GCGGGSSGGSGSGYVSSQQVTQT-------------- 217 Query: 328 RETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRG 387 S PS G SG F++ + G G G G G Sbjct: 218 ------------SCAPQPSYGGGSSGGGGSGGSG-----CFSSGGGGGSSGCGGGSSGIG 260 Query: 388 RGGPM-GRGGYGGGGSGGGGRGGFPSGGGGGG 418 G + G G GGGS GGG GG GG G G Sbjct: 261 SGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292 Score = 84.7 bits (208), Expect = 2e-16 Identities = 85/272 (31%), Positives = 94/272 (34%), Gaps = 34/272 (12%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG--QSQNTGYGTQSTPQGYGSTGGY-- 81 S Q QP Q S G G S G +G G+ + GY GGY Sbjct: 2 SYQKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG 61 Query: 82 ----GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG 137 G S G G G S GS G S S G SG +S G Sbjct: 62 GGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSS----G 117 Query: 138 GQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQ 197 G S G ++ G S GGGG G Q +SSGG SGGG G Sbjct: 118 GGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCF 177 Query: 198 DQSGGGGSG-GY--GQQDRGGRGRGGSGGG-------------------GGGGGGGYNRS 235 GGGGS GY G GG GGSG G GG GGG + Sbjct: 178 SSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237 Query: 236 SGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267 SG + G GG G GG G G GG Sbjct: 238 SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269 Score = 84.0 bits (206), Expect = 3e-16 Identities = 83/249 (33%), Positives = 88/249 (35%), Gaps = 39/249 (15%) Query: 51 GQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSST- 109 G SS S G S GY G GG G G Y G G S Sbjct: 44 GGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGC 103 Query: 110 -SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP-----------QGYGQ 157 S G S SS G SG S S GG S G ++ Q YG Sbjct: 104 FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGG 163 Query: 158 QNQYNSSSGGGG----GGGGGGNYGQDQSSMSSGGGSGGGYGNQ---------------- 197 + SS GG G GGGGG G GGGS GG G+ Sbjct: 164 VSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQP 223 Query: 198 ----DQSGGGGSGGYGQ-QDRGGRGRGGSGGGGGGGGGGYNRSSGGYE-PRGRGGGRGGR 251 SGGGGSGG G GG G G GGG G G G S GG G GG GG Sbjct: 224 SYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG 283 Query: 252 GGMGGSDRG 260 +GGS G Sbjct: 284 SSVGGSGSG 292 Score = 74.3 bits (181), Expect = 3e-13 Identities = 77/223 (34%), Positives = 86/223 (38%), Gaps = 28/223 (12%) Query: 34 GQQSYSGYSQSTDTSGYGQSSYSSYGQ-SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG 92 G S G S + G G +SS G S G G S+ G S GG G S + Sbjct: 93 GGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFS 152 Query: 93 QQS----SYPGYGQQPAPSSTSGSYGSSSQSSSY-GQPQSGSYSQQPSYGGQQQSYGQQQ 147 Q+ SY G + SG + S S G GS S GG Y Q Sbjct: 153 GQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQ 212 Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG- 206 Q + SSGGGG GG G SSGGG GG G GGG SG Sbjct: 213 QVTQTSCAPQPSYGGGSSGGGGSGGSG--------CFSSGGG-GGSSG----CGGGSSGI 259 Query: 207 GYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG 249 G G GG G G GGGGGG SS G G G G+G Sbjct: 260 GSGCIISGGGSVCGGGSSGGGGGG----SSVG----GSGSGKG 294 Score = 65.9 bits (159), Expect = 9e-11 Identities = 70/206 (33%), Positives = 81/206 (39%), Gaps = 60/206 (29%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT-GYGTQSTPQGYGSTGG 80 G G+S Q+ Q QSY G S S +SG G +SS G + GY + G GS+GG Sbjct: 148 GGGFSGQAVQC---QSYGGVS-SGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGG 203 Query: 81 YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQ 140 GS S Q S P QP SYG SG GG Sbjct: 204 SGSGYVSSQQVTQTSCAP----QP----------------SYGGGSSG--------GG-- 233 Query: 141 QSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQS 200 G G ++S GGG G GGG+ G + SGGGS Sbjct: 234 -------------GSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS--------VC 272 Query: 201 GGGGSGGYGQQDRGGRGRGGSGGGGG 226 GGG SGG G GG GGSG G G Sbjct: 273 GGGSSGGGG----GGSSVGGSGSGKG 294 Score = 64.7 bits (156), Expect = 2e-10 Identities = 55/149 (36%), Positives = 62/149 (41%), Gaps = 20/149 (13%) Query: 378 GGGNGRGGRGRGGPMGRGGY-GGGGSGGGGRGGFPSGGGG------GGGQQRAGDWKCPN 430 GGG G GG G GG G Y GGGGS GGG G F SGGGG GGG G C Sbjct: 72 GGGGGIGGCG-GGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGC-- 128 Query: 431 PTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYR--GRG 488 + G GG G + +YG GG G G + G G Sbjct: 129 -----FSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGG 183 Query: 489 GDRGGFRGGR---GGGDRGGFGPGKMDSR 514 G G+ GG GGG GG G G + S+ Sbjct: 184 GSVCGYSGGGSGCGGGSSGGSGSGYVSSQ 212 Score = 58.5 bits (140), Expect = 1e-08 Identities = 56/174 (32%), Positives = 68/174 (39%), Gaps = 30/174 (17%) Query: 378 GGGNGRGGRGRGGPMGR-------GGYGGGGSGGGGRGGFPSGGGGG------GGQQRAG 424 GGG+G G GG G+ GG GGS GGG G F SGGGGG GG G Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197 Query: 425 DWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG- 483 ++ S + C AP+P GG GG GG+ GG G GG Sbjct: 198 GGSSGGSGSGYVS-SQQVTQTSC-APQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGG 255 Query: 484 ---------YRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGE---HRQDRRERP 525 G G GG G GGG G G +G H+ +++ P Sbjct: 256 SSGIGSGCIISGGGSVCGG--GSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAP 307 Score = 46.6 bits (109), Expect = 6e-05 Identities = 33/80 (41%), Positives = 33/80 (41%), Gaps = 16/80 (20%) Query: 446 QCKAPKPDGP--------GGGPGGSHMGGNYGDDRRGGRG--------GYDRGGYRGRGG 489 Q K P P P GGG GG GG G GG G GY GG GG Sbjct: 4 QKKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGG 63 Query: 490 DRGGFRGGRGGGDRGGFGPG 509 GG GG GGG GG G G Sbjct: 64 CGGGSSGGGGGGGIGGCGGG 83 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 95.1 bits (235), Expect = 1e-19 Identities = 70/177 (39%), Positives = 75/177 (42%), Gaps = 37/177 (20%) Query: 92 GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151 G++S G S S S+ + S S G G S SYG SYG Sbjct: 488 GEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGS------ 541 Query: 152 PQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQ 211 GGGGGGG G+YG SS SGGGS G G GGGG G YG Sbjct: 542 ---------------GGGGGGGRGSYGSGGSSYGSGGGSYGSGG-----GGGGHGSYGSG 581 Query: 212 DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG-RGGRGGMGGSDRGGFNKFGG 267 G RGGSGGGGGG GG RG GGG GG G GS GG GG Sbjct: 582 SSSGGYRGGSGGGGGGSSGG----------RGSGGGSSGGSIGGRGSSSGGVKSSGG 628 Score = 92.8 bits (229), Expect = 7e-19 Identities = 62/145 (42%), Positives = 73/145 (50%), Gaps = 18/145 (12%) Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGG 220 + + SGGG GGGGG YG SS SGGGS G SGGGG GG G GG G Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG-------SGGGGGGGRGSYGSGGSSYGS 561 Query: 221 SGG--GGGGGGGGY-----NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGS 273 GG G GGGGGG+ SSGGY RG G G GG G GG GG + G +GS Sbjct: 562 GGGSYGSGGGGGGHGSYGSGSSSGGY--RG-GSGGGGGGSSGGRGSGGGSSGGSIGGRGS 618 Query: 274 RHDSEQDNSDNNTI-FVQGLGENVT 297 + + ++++ FV VT Sbjct: 619 SSGGVKSSGGSSSVKFVSTTYSGVT 643 Score = 76.6 bits (187), Expect = 5e-14 Identities = 58/164 (35%), Positives = 75/164 (45%), Gaps = 27/164 (16%) Query: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129 S+ GY S GG+ S + +Y ++++ SST S G + SS G GS Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTT---------SSSTRRSGGGGGRFSSCGGG-GGS 55 Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGG 189 + G +G + N G + + + GGG G G GG YG GG Sbjct: 56 F-------GAGGGFGSRSLVN--LGGSKSISISVARGGGRGSGFGGGYG-------GGGF 99 Query: 190 SGGGYGNQDQSGGG-GSGGYGQQDRGGRGRGGSGGGGGGGGGGY 232 GGG+G GGG G GG+G GG G GG G GGGG GGGY Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY 143 Score = 75.9 bits (185), Expect = 9e-14 Identities = 60/161 (37%), Positives = 66/161 (40%), Gaps = 53/161 (32%) Query: 364 IKVSFATRRADFNRGG--GNGRGGRGRGGPM---GRGGYGGGGSGGGGRGGFPSGG---G 415 + VS +T + GG G G GG G GG G G YG GG GGGGRG + SGG G Sbjct: 501 VSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYG 560 Query: 416 GGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGG 475 GGG G GGG GG G+YG Sbjct: 561 SGGGSY--------------------------------GSGGGGGGH---GSYG------ 579 Query: 476 RGGYDRGGYR-GRGGDRGGFRGGRGGGDRGGFGPGKMDSRG 515 G GGYR G GG GG GGRG G GG G + RG Sbjct: 580 -SGSSSGGYRGGSGGGGGGSSGGRGSG--GGSSGGSIGGRG 617 Score = 74.3 bits (181), Expect = 3e-13 Identities = 46/106 (43%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Query: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGG 215 G +++S GGGG G GG +G S+ + GGS + + GG GSG G GG Sbjct: 41 GGGGRFSSCGGGGGSFGAGGGFGS--RSLVNLGGSKSISISVARGGGRGSGFGGGYGGGG 98 Query: 216 RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 G GG GGGG GGGG GG+ G GGG G GG GG GG Sbjct: 99 FGGGGFGGGGFGGGG---IGGGGFGGFGSGGGGFGGGGFGGGGYGG 141 Score = 66.6 bits (161), Expect = 5e-11 Identities = 45/125 (36%), Positives = 57/125 (45%), Gaps = 14/125 (11%) Query: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSS--GGGSGGGYGNQDQSGG--GGSGGYGQ 210 + ++ Y S G G G NY + +S S+ GG GG + + GG G GG+G Sbjct: 5 FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64 Query: 211 QDRGGRGRGGS--------GGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGF 262 + G S GG G G GGGY GG+ G GGG G GG+GG GGF Sbjct: 65 RSLVNLGGSKSISISVARGGGRGSGFGGGY--GGGGFGGGGFGGGGFGGGGIGGGGFGGF 122 Query: 263 NKFGG 267 GG Sbjct: 123 GSGGG 127 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/122 (35%), Positives = 44/122 (36%), Gaps = 26/122 (21%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437 G G G G G GG GRG YG GGS G GG GGGGGG G Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG------------- 579 Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGG 497 GG GGS GG RG GG G GRG GG + Sbjct: 580 -------------SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSS 626 Query: 498 RG 499 G Sbjct: 627 GG 628 Score = 63.5 bits (153), Expect = 4e-10 Identities = 55/146 (37%), Positives = 56/146 (38%), Gaps = 36/146 (24%) Query: 76 GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135 G GGYGS SS S G YG GSYGS SSYG GSY Sbjct: 520 GGGGGYGSGGSSYGSGGGS-----YGSGGGGGGGRGSYGSGG--SSYGSG-GGSYGSGGG 571 Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYG 195 GG SYG S Y SGGGGGG GG GSGGG Sbjct: 572 -GGGHGSYGSGSS---------SGGYRGGSGGGGGGSSGGR------------GSGGG-- 607 Query: 196 NQDQSGGGGSGGYGQQDRGGRGRGGS 221 S GG GG G G + GGS Sbjct: 608 ----SSGGSIGGRGSSSGGVKSSGGS 629 Score = 62.4 bits (150), Expect = 1e-09 Identities = 50/141 (35%), Positives = 62/141 (43%), Gaps = 7/141 (4%) Query: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNP 431 R+ + GGG G G R GGG G F S GGGGG G + + Sbjct: 8 RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFG--SR 65 Query: 432 TCENMNFSWRNECNQCKAP-KPDGPGGGPGGSHM-GGNYGDDRRGGRGGYDRGGYRGRGG 489 + N+ S + + + G GGG GG GG +G GG GG GG+ G G Sbjct: 66 SLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGG-GGIGGGGFGGFGS 124 Query: 490 DRGGFRGG--RGGGDRGGFGP 508 GGF GG GGG GG+GP Sbjct: 125 GGGGFGGGGFGGGGYGGGYGP 145 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/56 (53%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTC 433 GGG G GG G GG G GG GGGG GG G GG GGGG GG G + P C Sbjct: 96 GGGFGGGGFGGGG-FGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGY---GPVC 147 Score = 45.8 bits (107), Expect = 1e-04 Identities = 46/128 (35%), Positives = 50/128 (39%), Gaps = 7/128 (5%) Query: 7 TQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGY 66 T T S G G GY S YG S G S G G+ SY S G S +G Sbjct: 507 TSHTTISGGGSRGGGGGGYGSGGSS-YG--SGGGSYGSGGGGGGGRGSYGSGGSSYGSGG 563 Query: 67 GTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSS---SQSSSYG 123 G+ + G G G YGS SS Y S G G S GS G S SSS G Sbjct: 564 GSYGSGGGGGGHGSYGSG-SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622 Query: 124 QPQSGSYS 131 SG S Sbjct: 623 VKSSGGSS 630 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/70 (41%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 454 GPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDR-----GGFRGGRGGGDRGGFGP 508 G G G GGS G G GG GG RG Y G GG G + G GGG G +G Sbjct: 522 GGGYGSGGSSYGSGGGSYGSGGGGGGGRGSY-GSGGSSYGSGGGSYGSGGGGGGHGSYGS 580 Query: 509 GKMDSRGEHR 518 G S G +R Sbjct: 581 G--SSSGGYR 588 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/115 (34%), Positives = 45/115 (39%), Gaps = 35/115 (30%) Query: 181 QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG------GGGGGYNR 234 Q S SG SGGG+ + G +G Q R GGGG GGGGG Sbjct: 4 QFSSRSGYRSGGGFSS------GSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFG 57 Query: 235 SSGGYEPR---------------GRGGGRG-------GRGGMGGSDRGGFNKFGG 267 + GG+ R RGGGRG G GG GG GG FGG Sbjct: 58 AGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGG-GGFGG 111 Score = 41.6 bits (96), Expect = 0.002 Identities = 43/151 (28%), Positives = 47/151 (31%), Gaps = 45/151 (29%) Query: 40 GYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPG 99 GY + G G SY S G S YGS GG SYG G Sbjct: 524 GYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG---------SYGSGGGGGG 574 Query: 100 YGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159 + GSYGS S S Y G GG S G+ Sbjct: 575 H----------GSYGSGSSSGGYRGGSGG--------GGGGSSGGR-------------- 602 Query: 160 QYNSSSGGGGGGGGGGNYGQDQSSMSSGGGS 190 SGGG GG G G + S GGS Sbjct: 603 ----GSGGGSSGGSIGGRGSSSGGVKSSGGS 629 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/111 (33%), Positives = 44/111 (39%), Gaps = 7/111 (6%) Query: 14 YGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG-YGTQSTP 72 YG+ + G G S G Y + G G SY S G G YG+ S+ Sbjct: 525 YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584 Query: 73 QGY--GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS 121 GY GS GG G S + S G S G S+SG SS SSS Sbjct: 585 GGYRGGSGGGGGGSSGGRGSGGGSSG----GSIGGRGSSSGGVKSSGGSSS 631 Score = 38.5 bits (88), Expect = 0.015 Identities = 24/46 (52%), Positives = 26/46 (56%), Gaps = 9/46 (19%) Query: 378 GGGNGRGGRGRGG----PMGRGGYGGGG-SGGGGRGGF----PSGG 414 GGG G GG G GG G GG+GGGG GGG GG+ P GG Sbjct: 106 GGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151 Score = 30.0 bits (66), Expect = 5.4 Identities = 22/62 (35%), Positives = 23/62 (37%), Gaps = 4/62 (6%) Query: 213 RGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272 R G GG G G Y R + R GGG GG S GG FG G Sbjct: 8 RSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGG----GGRFSSCGGGGGSFGAGGGFG 63 Query: 273 SR 274 SR Sbjct: 64 SR 65 >gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo sapiens] Length = 898 Score = 94.0 bits (232), Expect = 3e-19 Identities = 83/263 (31%), Positives = 103/263 (39%), Gaps = 56/263 (21%) Query: 33 YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGY-----GSTGGYGSSQSS 87 +G ++ GY + G G SY G S GY + G+ G GG G S Sbjct: 661 FGGANHGGYMNA----GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 716 Query: 88 QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY-GQQ 146 SY Q +Y P P +G QP G Q+PSYG QS+ GQQ Sbjct: 717 YGSYYQGDNY----NSPVPPKHAGKK----------QPHGGQ--QKPSYGSGYQSHQGQQ 760 Query: 147 QSYN--------PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQD 198 QSYN PPQG +Q YN G G+Y S S GGG G Y + Sbjct: 761 QSYNQSPYSNYGPPQG--KQKGYNH---------GQGSYSYSNSYNSPGGGGGSDYNYES 809 Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258 + GSGG R G G G GG YN S G G GGG +G GG Sbjct: 810 KFNYSGSGG----------RSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 858 Query: 259 RGGFNKFGGPRDQGSRHDSEQDN 281 + +N G ++ S Q + Sbjct: 859 QSNYNSPGSGQNYSGPPSSYQSS 881 Score = 93.2 bits (230), Expect = 5e-19 Identities = 84/250 (33%), Positives = 104/250 (41%), Gaps = 56/250 (22%) Query: 49 GYGQSSYSSYGQSQNTGYGTQSTPQGYG---STGGYGSSQSSQSSYGQQSSYPGYGQQPA 105 G+G +++ Y + GYG+ GYG +T GY S+ G S G G Sbjct: 660 GFGGANHGGY-MNAGAGYGSY----GYGGNSATAGYSQFYSNGGHSGNASGGGGGG---- 710 Query: 106 PSSTSGSYGSSSQSSSYGQPQSGSYS--QQPSYGGQQQSY--------GQQQSYN----- 150 S YGS Q +Y P ++ +QP G Q+ SY GQQQSYN Sbjct: 711 -GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 769 Query: 151 ---PPQG-----------YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196 PPQG Y N YNS GGGGG NY + SGG SGG Sbjct: 770 NYGPPQGKQKGYNHGQGSYSYSNSYNSP---GGGGGSDYNYESKFNYSGSGGRSGG---- 822 Query: 197 QDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGGYNRSSGGYEPRGRGGGRGGRGGM 254 S G G Y GG G GGSGGG G GGY++S+ Y G G G Sbjct: 823 --NSYGSGGASYNPGSHGGYG-GGSGGGSSYQGKQGGYSQSN--YNSPGSGQNYSGPPSS 877 Query: 255 GGSDRGGFNK 264 S +GG+ + Sbjct: 878 YQSSQGGYGR 887 Score = 68.2 bits (165), Expect = 2e-11 Identities = 76/234 (32%), Positives = 88/234 (37%), Gaps = 51/234 (21%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG------QSSYSSYGQSQN 63 A YG+Y GY S+ Q YS S + SG G S Y SY Q N Sbjct: 672 AGAGYGSY------GYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDN 725 Query: 64 TG-------------YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ-QPAPSST 109 +G Q P YGS GY S Q Q SY Q S Y YG Q Sbjct: 726 YNSPVPPKHAGKKQPHGGQQKPS-YGS--GYQSHQGQQQSYNQ-SPYSNYGPPQGKQKGY 781 Query: 110 SGSYGSSSQSSSYGQPQSG-----SYSQQPSYGGQQ-----QSYGQQ-QSYNPPQ--GYG 156 + GS S S+SY P G +Y + +Y G SYG SYNP GYG Sbjct: 782 NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYG 841 Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210 + SS G GG NY + GSG Y S GGYG+ Sbjct: 842 GGSGGGSSYQGKQGGYSQSNY--------NSPGSGQNYSGPPSSYQSSQGGYGR 887 Score = 62.8 bits (151), Expect = 8e-10 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 72/317 (22%) Query: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G P+ + P +G + + PP G+ + G G G GG N+G + Sbjct: 614 GGPKFAAKPHNPGFGMGGPMHNEVPP--PPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN 671 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 + G GYG+ G + GY Q G G + GGGGGGGGG S GY Sbjct: 672 A-------GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGG----SSGYGSY 720 Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNS-DNNTIFVQGLGENVTIE 299 +G +N P+ G + H +Q S + QG ++ Sbjct: 721 YQG--------------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQS 766 Query: 300 SVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD---DPPSAKAAIDW-FD 355 ++Y G P ++ G G+ + S+ + P D+ ++ Sbjct: 767 PYSNY-------------GPPQ-----GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 808 Query: 356 GK-EFSGNPIKVSFATRRADFNRGGGNGRGGRGRG-GPMGRGGYGGGGSGG----GGRGG 409 K +SG+ R GGN G G P GGYGGG GG G +GG Sbjct: 809 SKFNYSGSG------------GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG 856 Query: 410 FPSG--GGGGGGQQRAG 424 + G GQ +G Sbjct: 857 YSQSNYNSPGSGQNYSG 873 Score = 61.2 bits (147), Expect = 2e-09 Identities = 63/240 (26%), Positives = 86/240 (35%), Gaps = 43/240 (17%) Query: 98 PGYGQQPAPSST-----SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152 P + + P P + GS + +G G Y + G G + Sbjct: 632 PMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS 691 Query: 153 QGYGQQNQYNSSSGGGGGGGGG----GNYGQDQSSMS------------SGGGSGGGYGN 196 Q Y ++SGGGGGGGGG G+Y Q + S GG YG+ Sbjct: 692 QFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS 751 Query: 197 QDQSGGGGSGGYGQQDRG------GRGRGGSGG------------GGGGGGGGYNRSSGG 238 QS G Y Q G+ +G + G GGGGG YN S Sbjct: 752 GYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYES-K 810 Query: 239 YEPRGRGGGRGGRG-GMGGS--DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295 + G GG GG G GG+ + G +GG GS + +Q + G G+N Sbjct: 811 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 870 Score = 53.9 bits (128), Expect = 4e-07 Identities = 46/142 (32%), Positives = 56/142 (39%), Gaps = 28/142 (19%) Query: 6 YTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSY------- 58 Y Q +YG P QG +Q +GQ SYS YS S ++ G G S +Y Sbjct: 763 YNQSPYSNYG-----PPQG--KQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYS 814 Query: 59 ---GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 G+S YG+ GS GGYG SSY Q GY Q +Y S Sbjct: 815 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQ--------SNYNS 864 Query: 116 SSQSSSYGQPQSGSYSQQPSYG 137 +Y P S S Q YG Sbjct: 865 PGSGQNYSGPPSSYQSSQGGYG 886 Score = 50.1 bits (118), Expect = 5e-06 Identities = 58/217 (26%), Positives = 68/217 (31%), Gaps = 83/217 (38%) Query: 377 RGGGNGRGGRGRGGPMGRG-GYGGGGSGG-------------GGRGGFPSGGGGG----- 417 RG G G GG GG M G GYG G GG GG G SGGGGG Sbjct: 655 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 714 Query: 418 ---------------------------GGQQRAG---------------------DWKCP 429 GGQQ+ ++ P Sbjct: 715 SGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP 774 Query: 430 NPTCENMN-----FSWRNECNQCKAPKPDGPGGGPGGSHMGGNY-GDDRRGGRGGYDRGG 483 + N +S+ N N P G GG NY G R G Y GG Sbjct: 775 QGKQKGYNHGQGSYSYSNSYNS-----PGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG 829 Query: 484 YRGRGGDRGGFRGGRGGGD-----RGGFGPGKMDSRG 515 G GG+ GG GGG +GG+ +S G Sbjct: 830 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 866 Score = 39.3 bits (90), Expect = 0.009 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 5 DYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT 64 +Y+ +S G G Y+ S YG S G S GY QS+Y+S G QN Sbjct: 812 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 871 Query: 65 GYGTQSTPQGYGSTGGYGSSQSSQSSY 91 G S+ Q S GGYG + +Y Sbjct: 872 S-GPPSSYQ--SSQGGYGRNADHSMNY 895 Score = 30.4 bits (67), Expect = 4.2 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 449 APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG-YRGRGGDRGGFRGGRGGGDRGGFG 507 A KP PG G GG GRG RGG RGRG RG GG G G Sbjct: 619 AAKPHNPGFGMGGPMHNEVPPPPNLRGRG---RGGSIRGRGRGRGFGGANHGGYMNAGAG 675 Query: 508 PG 509 G Sbjct: 676 YG 677 >gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo sapiens] Length = 894 Score = 94.0 bits (232), Expect = 3e-19 Identities = 83/263 (31%), Positives = 103/263 (39%), Gaps = 56/263 (21%) Query: 33 YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGY-----GSTGGYGSSQSS 87 +G ++ GY + G G SY G S GY + G+ G GG G S Sbjct: 657 FGGANHGGYMNA----GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 712 Query: 88 QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY-GQQ 146 SY Q +Y P P +G QP G Q+PSYG QS+ GQQ Sbjct: 713 YGSYYQGDNY----NSPVPPKHAGKK----------QPHGGQ--QKPSYGSGYQSHQGQQ 756 Query: 147 QSYN--------PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQD 198 QSYN PPQG +Q YN G G+Y S S GGG G Y + Sbjct: 757 QSYNQSPYSNYGPPQG--KQKGYNH---------GQGSYSYSNSYNSPGGGGGSDYNYES 805 Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258 + GSGG R G G G GG YN S G G GGG +G GG Sbjct: 806 KFNYSGSGG----------RSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854 Query: 259 RGGFNKFGGPRDQGSRHDSEQDN 281 + +N G ++ S Q + Sbjct: 855 QSNYNSPGSGQNYSGPPSSYQSS 877 Score = 93.2 bits (230), Expect = 5e-19 Identities = 84/250 (33%), Positives = 104/250 (41%), Gaps = 56/250 (22%) Query: 49 GYGQSSYSSYGQSQNTGYGTQSTPQGYG---STGGYGSSQSSQSSYGQQSSYPGYGQQPA 105 G+G +++ Y + GYG+ GYG +T GY S+ G S G G Sbjct: 656 GFGGANHGGY-MNAGAGYGSY----GYGGNSATAGYSQFYSNGGHSGNASGGGGGG---- 706 Query: 106 PSSTSGSYGSSSQSSSYGQPQSGSYS--QQPSYGGQQQSY--------GQQQSYN----- 150 S YGS Q +Y P ++ +QP G Q+ SY GQQQSYN Sbjct: 707 -GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 765 Query: 151 ---PPQG-----------YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196 PPQG Y N YNS GGGGG NY + SGG SGG Sbjct: 766 NYGPPQGKQKGYNHGQGSYSYSNSYNSP---GGGGGSDYNYESKFNYSGSGGRSGG---- 818 Query: 197 QDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGGYNRSSGGYEPRGRGGGRGGRGGM 254 S G G Y GG G GGSGGG G GGY++S+ Y G G G Sbjct: 819 --NSYGSGGASYNPGSHGGYG-GGSGGGSSYQGKQGGYSQSN--YNSPGSGQNYSGPPSS 873 Query: 255 GGSDRGGFNK 264 S +GG+ + Sbjct: 874 YQSSQGGYGR 883 Score = 68.2 bits (165), Expect = 2e-11 Identities = 76/234 (32%), Positives = 88/234 (37%), Gaps = 51/234 (21%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG------QSSYSSYGQSQN 63 A YG+Y GY S+ Q YS S + SG G S Y SY Q N Sbjct: 668 AGAGYGSY------GYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDN 721 Query: 64 TG-------------YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ-QPAPSST 109 +G Q P YGS GY S Q Q SY Q S Y YG Q Sbjct: 722 YNSPVPPKHAGKKQPHGGQQKPS-YGS--GYQSHQGQQQSYNQ-SPYSNYGPPQGKQKGY 777 Query: 110 SGSYGSSSQSSSYGQPQSG-----SYSQQPSYGGQQ-----QSYGQQ-QSYNPPQ--GYG 156 + GS S S+SY P G +Y + +Y G SYG SYNP GYG Sbjct: 778 NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYG 837 Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210 + SS G GG NY + GSG Y S GGYG+ Sbjct: 838 GGSGGGSSYQGKQGGYSQSNY--------NSPGSGQNYSGPPSSYQSSQGGYGR 883 Score = 62.8 bits (151), Expect = 8e-10 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 72/317 (22%) Query: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G P+ + P +G + + PP G+ + G G G GG N+G + Sbjct: 610 GGPKFAAKPHNPGFGMGGPMHNEVPP--PPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN 667 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 + G GYG+ G + GY Q G G + GGGGGGGGG S GY Sbjct: 668 A-------GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGG----SSGYGSY 716 Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNS-DNNTIFVQGLGENVTIE 299 +G +N P+ G + H +Q S + QG ++ Sbjct: 717 YQG--------------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQS 762 Query: 300 SVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD---DPPSAKAAIDW-FD 355 ++Y G P ++ G G+ + S+ + P D+ ++ Sbjct: 763 PYSNY-------------GPPQ-----GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 804 Query: 356 GK-EFSGNPIKVSFATRRADFNRGGGNGRGGRGRG-GPMGRGGYGGGGSGG----GGRGG 409 K +SG+ R GGN G G P GGYGGG GG G +GG Sbjct: 805 SKFNYSGSG------------GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG 852 Query: 410 FPSG--GGGGGGQQRAG 424 + G GQ +G Sbjct: 853 YSQSNYNSPGSGQNYSG 869 Score = 61.2 bits (147), Expect = 2e-09 Identities = 63/240 (26%), Positives = 86/240 (35%), Gaps = 43/240 (17%) Query: 98 PGYGQQPAPSST-----SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152 P + + P P + GS + +G G Y + G G + Sbjct: 628 PMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS 687 Query: 153 QGYGQQNQYNSSSGGGGGGGGG----GNYGQDQSSMS------------SGGGSGGGYGN 196 Q Y ++SGGGGGGGGG G+Y Q + S GG YG+ Sbjct: 688 QFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS 747 Query: 197 QDQSGGGGSGGYGQQDRG------GRGRGGSGG------------GGGGGGGGYNRSSGG 238 QS G Y Q G+ +G + G GGGGG YN S Sbjct: 748 GYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYES-K 806 Query: 239 YEPRGRGGGRGGRG-GMGGS--DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295 + G GG GG G GG+ + G +GG GS + +Q + G G+N Sbjct: 807 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 866 Score = 53.9 bits (128), Expect = 4e-07 Identities = 46/142 (32%), Positives = 56/142 (39%), Gaps = 28/142 (19%) Query: 6 YTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSY------- 58 Y Q +YG P QG +Q +GQ SYS YS S ++ G G S +Y Sbjct: 759 YNQSPYSNYG-----PPQG--KQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYS 810 Query: 59 ---GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 G+S YG+ GS GGYG SSY Q GY Q +Y S Sbjct: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQ--------SNYNS 860 Query: 116 SSQSSSYGQPQSGSYSQQPSYG 137 +Y P S S Q YG Sbjct: 861 PGSGQNYSGPPSSYQSSQGGYG 882 Score = 50.1 bits (118), Expect = 5e-06 Identities = 58/217 (26%), Positives = 68/217 (31%), Gaps = 83/217 (38%) Query: 377 RGGGNGRGGRGRGGPMGRG-GYGGGGSGG-------------GGRGGFPSGGGGG----- 417 RG G G GG GG M G GYG G GG GG G SGGGGG Sbjct: 651 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 710 Query: 418 ---------------------------GGQQRAG---------------------DWKCP 429 GGQQ+ ++ P Sbjct: 711 SGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP 770 Query: 430 NPTCENMN-----FSWRNECNQCKAPKPDGPGGGPGGSHMGGNY-GDDRRGGRGGYDRGG 483 + N +S+ N N P G GG NY G R G Y GG Sbjct: 771 QGKQKGYNHGQGSYSYSNSYNS-----PGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG 825 Query: 484 YRGRGGDRGGFRGGRGGGD-----RGGFGPGKMDSRG 515 G GG+ GG GGG +GG+ +S G Sbjct: 826 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 862 Score = 39.3 bits (90), Expect = 0.009 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 5 DYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT 64 +Y+ +S G G Y+ S YG S G S GY QS+Y+S G QN Sbjct: 808 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867 Query: 65 GYGTQSTPQGYGSTGGYGSSQSSQSSY 91 G S+ Q S GGYG + +Y Sbjct: 868 S-GPPSSYQ--SSQGGYGRNADHSMNY 891 Score = 30.4 bits (67), Expect = 4.2 Identities = 25/62 (40%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 449 APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGG-YRGRGGDRGGFRGGRGGGDRGGFG 507 A KP PG G GG GRG RGG RGRG RG GG G G Sbjct: 615 AAKPHNPGFGMGGPMHNEVPPPPNLRGRG---RGGSIRGRGRGRGFGGANHGGYMNAGAG 671 Query: 508 PG 509 G Sbjct: 672 YG 673 >gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens] Length = 305 Score = 93.6 bits (231), Expect = 4e-19 Identities = 80/240 (33%), Positives = 109/240 (45%), Gaps = 41/240 (17%) Query: 273 SRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRET 330 SR DS + + +FV GL +V + ++F Q G ++ + + D+++ Sbjct: 84 SREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE--------IIADKQS 135 Query: 331 GKLKGEATVSFDDPPSA-KAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG------- 382 GK +G V F + +A KAA+ F G+ ++V A + D GGG G Sbjct: 136 GKKRGFGFVYFQNHDAADKAAVVKFH--PIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRG 193 Query: 383 -RGGRGRGGP-----MGRGGYGG----GGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPT 432 RGGRGRGG + +GG GG GG GGGG GG+ + GGGGGG G + Sbjct: 194 GRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGS----DYG 249 Query: 433 CENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRG 492 F ++ P G GGG GGS GG R G Y RGGY G GG G Sbjct: 250 NGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGG------RSNSGPY-RGGYGGGGGYGG 302 Score = 81.6 bits (200), Expect = 2e-15 Identities = 52/114 (45%), Positives = 59/114 (51%), Gaps = 13/114 (11%) Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR--GG 220 SS GG GG G GG G+DQ+ +S GGG GGY + GGGG GGY GG G GG Sbjct: 190 SSRGGRGGRGRGG--GRDQNGLSKGGG--GGYNSYGGYGGGGGGGYNAYGGGGGGSSYGG 245 Query: 221 SG-GGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM------GGSDRGGFNKFGG 267 S G G GG G Y++ Y P GGG GG G G RGG+ GG Sbjct: 246 SDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGG 299 Score = 80.9 bits (198), Expect = 3e-15 Identities = 57/133 (42%), Positives = 64/133 (48%), Gaps = 19/133 (14%) Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN-YGQDQSSMSS 186 GS S + GG+ + G+ Q+ G G YNS G GGGGGGG N YG Sbjct: 187 GSRSSRGGRGGRGRGGGRDQNGLSKGGGGG---YNSYGGYGGGGGGGYNAYG-------- 235 Query: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG--GYNRSSGGYEPRGR 244 GGG G YG D G G G Q + G SGGGGGGGG G +SG Y Sbjct: 236 GGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYR---- 291 Query: 245 GGGRGGRGGMGGS 257 GG GG GG GGS Sbjct: 292 -GGYGGGGGYGGS 303 Score = 63.2 bits (152), Expect = 6e-10 Identities = 39/86 (45%), Positives = 43/86 (50%), Gaps = 15/86 (17%) Query: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGS----GGGGGGGGGGYNRSSGGYEP 241 SGGG GG ++ GG G GG Q+ +G GG GG GGGGGGGYN GG Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG--- 237 Query: 242 RGRGGGRGGRGGMGGSDRG-GFNKFG 266 GG GGSD G GF FG Sbjct: 238 -------GGGSSYGGSDYGNGFGGFG 256 Score = 60.5 bits (145), Expect = 4e-09 Identities = 51/141 (36%), Positives = 61/141 (43%), Gaps = 29/141 (20%) Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ--- 133 S GG G S+SS+ G + G Q G Y S YG G Y+ Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYG---GYGGGGGGGYNAYGGG 237 Query: 134 ---PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG----GGGGGGGGGNYGQDQSSMSS 186 SYGG YG N G+G +Q+ SS G GGGGGGGG ++G S+ Sbjct: 238 GGGSSYGGS--DYG-----NGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWG----GRSN 286 Query: 187 GGGSGGGYGNQDQSGGGGSGG 207 G GGYG GGGG GG Sbjct: 287 SGPYRGGYG-----GGGGYGG 302 Score = 52.8 bits (125), Expect = 8e-07 Identities = 33/82 (40%), Positives = 37/82 (45%), Gaps = 12/82 (14%) Query: 200 SGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR 259 SGGGG G RGG GG G GGG N S +G GGG GG GG Sbjct: 181 SGGGGGGSRSS-------RGGRGGRGRGGGRDQNGLS-----KGGGGGYNSYGGYGGGGG 228 Query: 260 GGFNKFGGPRDQGSRHDSEQDN 281 GG+N +GG S S+ N Sbjct: 229 GGYNAYGGGGGGSSYGGSDYGN 250 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/72 (41%), Positives = 33/72 (45%), Gaps = 16/72 (22%) Query: 450 PKPD---GPGGGPGGSHMGGNYGDDRRGGR----------GGYDR-GGYRGRGGDRGGFR 495 PK D G GGG S GG G R GGR GGY+ GGY G GG GG+ Sbjct: 175 PKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGG--GGYN 232 Query: 496 GGRGGGDRGGFG 507 GGG +G Sbjct: 233 AYGGGGGGSSYG 244 Score = 35.8 bits (81), Expect = 0.099 Identities = 19/33 (57%), Positives = 20/33 (60%), Gaps = 3/33 (9%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGF 410 GGG+ GGR GP RGGYGGGG G G F Sbjct: 276 GGGSSWGGRSNSGPY-RGGYGGGG--GYGGSSF 305 Score = 33.1 bits (74), Expect = 0.64 Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 13/85 (15%) Query: 13 SYGAYPTQPGQGYSQQSS----QPYGQQSYS-------GYSQSTDTSGYGQSSYSSYGQS 61 SYG Y G GY+ YG Y YSQ + G +S G Sbjct: 219 SYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGG 278 Query: 62 QNTGYGTQSTPQ--GYGSTGGYGSS 84 + G + S P GYG GGYG S Sbjct: 279 SSWGGRSNSGPYRGGYGGGGGYGGS 303 >gi|186928825 dermokine isoform 3 precursor [Homo sapiens] Length = 416 Score = 92.8 bits (229), Expect = 7e-19 Identities = 76/244 (31%), Positives = 100/244 (40%), Gaps = 38/244 (15%) Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126 ++GG+G S GQ PG P P +++GS+G + Q + +GQ P Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203 Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G+ +Q QP YG + S + NPP S SGGG GGG+ Q Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 S SSG GS G N SGG SG GG G SG GG G + SS G Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 243 GRGGGRGGRGGMGGSDRG-----------GFNKFGGPRDQGSRHDSEQDNSDNNTIFVQG 291 G GG GG G G G + G R QG + + + + N + + G Sbjct: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL-LGG 370 Query: 292 LGEN 295 G+N Sbjct: 371 SGDN 374 Score = 66.2 bits (160), Expect = 7e-11 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%) Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427 G G GG+G+G P G G GY G +G G G P G GG GG G Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211 Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485 P ++ S +NE C P P G GGG G G G G G + G Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269 Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516 G G GG GG GG G G + DS E Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303 Score = 54.7 bits (130), Expect = 2e-07 Identities = 60/196 (30%), Positives = 72/196 (36%), Gaps = 20/196 (10%) Query: 32 PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89 P+GQ G T+T G Q Y S S T P G G G S +S Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246 Query: 90 SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147 G QS G G + S+SG SSS SSS G S + GG + G + Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304 Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGG 207 S+ G SSSG GG GGG + + G G Q G G S Sbjct: 305 SWGSSTG--------SSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356 Query: 208 YGQ-QDRGGRGRGGSG 222 + G R GGSG Sbjct: 357 MREISKEGNRLLGGSG 372 Score = 54.3 bits (129), Expect = 3e-07 Identities = 60/197 (30%), Positives = 79/197 (40%), Gaps = 24/197 (12%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70 T + GA QPG G + S+Q G + SG G S +S G G G+QS Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252 Query: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQSG 128 G GS G + SS S SS G SS + GS G S SS+G S Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG---SS 309 Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSG- 187 + S ++GG G + P G + + + SG G G G + + S Sbjct: 310 TGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMREISKEGNR 366 Query: 188 --GGSGGGYGNQDQSGG 202 GGSG Y N + S G Sbjct: 367 LLGGSGDNYRNSETSPG 383 Score = 50.4 bits (119), Expect = 4e-06 Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%) Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211 G+G + + G G GG G S ++ G G G + G G + G + Sbjct: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99 Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256 G +G G G G +G +E G G G +GG+GG Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159 Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316 +G G P G +S N G G N + TN + Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209 Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376 + R + + +G + PPS G SG Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247 Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 G +G G G G G GG S G GG SGG GG +G + + Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496 SW + G G G GGN G + G ++ G RG G +G Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347 Query: 497 GRGGG 501 RG G Sbjct: 348 FRGQG 352 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%) Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414 GN G G +G P G+GG GG + G G PSG Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237 Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468 GGG G + N N + + GG GGS + GG+ Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297 Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505 GD G G G G GG G + G ++ G Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334 Score = 43.1 bits (100), Expect = 6e-04 Identities = 91/396 (22%), Positives = 129/396 (32%), Gaps = 51/396 (12%) Query: 78 TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136 +G G QS + S G G+G A S G + G S + Q Sbjct: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73 Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188 G +++ G P G+G + + G G G G+ + G Sbjct: 74 -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130 Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245 G G G + SGG G G Q GG+G+G GG G GY +S G Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189 Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302 G G+GG GG G N G G R ++ + N G G + S Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSS---NSGG 246 Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362 Q G + +G N G G ++ S ++ + + SG+ Sbjct: 247 GSGSQSG----SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGS 302 Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGG-------- 414 +T + N GG GG G + G GSG G GF G Sbjct: 303 ESSWGSSTGSSSGNHGGSG--GGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREI 360 Query: 415 --------GGGGGQQRAGDWKCPNPTCENMNFSWRN 442 GG G R + +P N + W+N Sbjct: 361 SKEGNRLLGGSGDNYRNSE---TSPGMFNFDTFWKN 393 >gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b [Homo sapiens] Length = 372 Score = 92.4 bits (228), Expect = 9e-19 Identities = 69/188 (36%), Positives = 86/188 (45%), Gaps = 29/188 (15%) Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGG 174 +S+ SS G+ SG++ GG+ +G ++ + + + S GGGG GG G Sbjct: 187 ASASSSQRGRSGSGNFG-----GGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSG 241 Query: 175 GNY------------GQDQSSMSSGGGSGG-GYGNQDQSGGGGSGGYGQQDRGGRG--RG 219 Y G S S G GSGG GYGNQ SG GGSG Y + GG G G Sbjct: 242 DGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQG-SGYGGSGSYDSYNNGGGGGFGG 300 Query: 220 GSGGGGGGGG-----GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR 274 GSG GGGG G YN S + P +GG GGR G GG F PR+QG Sbjct: 301 GSGSNFGGGGSYNDFGNYNNQSSNFGPM-KGGNFGGRS--SGPYGGGGQYFAKPRNQGGY 357 Query: 275 HDSEQDNS 282 S +S Sbjct: 358 GGSSSSSS 365 Score = 85.9 bits (211), Expect = 8e-17 Identities = 85/271 (31%), Positives = 117/271 (43%), Gaps = 41/271 (15%) Query: 268 PRDQGSRHDSEQDNSDNNT--IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLY 325 P+ SR DS++ + IFV G+ E+ + DYF+Q G I+ +I + Sbjct: 86 PKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIE--------VIEIM 137 Query: 326 TDRETGKLKGEATVSFDDPPSA-KAAIDWFDG---------KEFSGNPIKVSFATRRA-- 373 TDR +GK +G A V+FDD S K I + K S + + +++R Sbjct: 138 TDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRS 197 Query: 374 ---DFNRGGGNGRGGR---GRGGPM-GRGGYGG----GGSGGGGRG--GFPSGGG-GGGG 419 +F G G G GG GRGG GRGG+GG GG GG G G GF + GG GGGG Sbjct: 198 GSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGG 257 Query: 420 QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY 479 +G + + + GGG G G N+G GG Sbjct: 258 PGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFG----GGGSYN 313 Query: 480 DRGGYRGRGGDRGGFRGGR-GGGDRGGFGPG 509 D G Y + + G +GG GG G +G G Sbjct: 314 DFGNYNNQSSNFGPMKGGNFGGRSSGPYGGG 344 Score = 82.4 bits (202), Expect = 9e-16 Identities = 67/210 (31%), Positives = 83/210 (39%), Gaps = 45/210 (21%) Query: 44 STDTSGYGQSSYSSYGQSQNTGYGTQST---PQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100 S +S G+S ++G + G+G + GG+G S+ G Y G+ Sbjct: 188 SASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGF 247 Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ 160 G G YG S G GS Q YG Q YG G G + Sbjct: 248 GND-------GGYGGGGPGYSGGSRGYGSGGQ--GYGNQGSGYG---------GSGSYDS 289 Query: 161 YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG---GGYGNQDQSGGGGSGGYGQQDRGGRG 217 YN+ GGG GGG G N+G GGGS G Y NQ + G GG + GGR Sbjct: 290 YNNGGGGGFGGGSGSNFG--------GGGSYNDFGNYNNQSSNFGPMKGG----NFGGRS 337 Query: 218 RGGSGGGG---------GGGGGGYNRSSGG 238 G GGGG GG GG + SS G Sbjct: 338 SGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367 Score = 66.2 bits (160), Expect = 7e-11 Identities = 66/232 (28%), Positives = 80/232 (34%), Gaps = 50/232 (21%) Query: 1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQ--SYSGYSQSTDTSGYGQSSYSSY 58 MAS +Q+ G + G G+ + G G+ S GYG S Sbjct: 186 MASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS----- 240 Query: 59 GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQ 118 GY G+G+ GGYG PGY + GS G S Sbjct: 241 ----GDGY------NGFGNDGGYGGGG------------PGY--------SGGSRGYGSG 270 Query: 119 SSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYG 178 YG SG YGG G SYN G G S+ GGGG GNY Sbjct: 271 GQGYGNQGSG-------YGGS----GSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYN 319 Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGG 230 S+ G GG +G + GG G Y + R G GGS G G Sbjct: 320 NQSSNF--GPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/99 (44%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 179 QDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG---GGGGYNRS 235 Q+ +S SS G GN GGG GG+G D GRG SG GG G GGGGY S Sbjct: 184 QEMASASSSQRGRSGSGN---FGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 240 Query: 236 SGGYEPRGRGGGRGGRG-GMGGSDRGGFNKFGGPRDQGS 273 GY G GG GG G G G RG + G +QGS Sbjct: 241 GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGS 279 Score = 53.5 bits (127), Expect = 5e-07 Identities = 41/127 (32%), Positives = 47/127 (37%), Gaps = 14/127 (11%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMN 437 GGG G G RG G GYG GSG GG G + S GGGG G N Sbjct: 255 GGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGG---------SGSN 305 Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGG 497 F N GP GGN+G G GG G Y + ++GG+ G Sbjct: 306 FGGGGSYNDFGNYNNQSSNFGP---MKGGNFGGRSSGPYGG--GGQYFAKPRNQGGYGGS 360 Query: 498 RGGGDRG 504 G Sbjct: 361 SSSSSYG 367 Score = 31.6 bits (70), Expect = 1.9 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 51/116 (43%) Query: 375 FNRGGGNGRGGRGRGGPMGRGG--------------YG---GGGSGGGGRGGFPSGGGGG 417 +N GGG G GG G G G GG +G GG GG G + GG Sbjct: 290 YNNGGGGGFGG-GSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPY-----GG 343 Query: 418 GGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRR 473 GGQ A RN+ GG GGS +YG RR Sbjct: 344 GGQYFAKP---------------RNQ-------------GGYGGSSSSSSYGSGRR 371 >gi|109452587 family with sequence similarity 98, member B isoform 1 [Homo sapiens] Length = 433 Score = 92.0 bits (227), Expect = 1e-18 Identities = 55/118 (46%), Positives = 62/118 (52%), Gaps = 21/118 (17%) Query: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210 PP+ Q + G GG GGGGG GGG GGG GGGG GG+G Sbjct: 319 PPEMPPWQKRQEGGGGRGGWGGGGG-----------GGGRGGG------GGGGGRGGWG- 360 Query: 211 QDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG-SDRGGFNKFGG 267 GG G GG GGGGGG GGG GG++ RG GGRGG GG GG RG + +GG Sbjct: 361 --GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGG 416 Score = 90.9 bits (224), Expect = 3e-18 Identities = 63/132 (47%), Positives = 64/132 (48%), Gaps = 36/132 (27%) Query: 379 GGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGG-GGGQQRAGDWKCPNPTCENMN 437 GG GRGG G GG G GG GGGG GGGGRGG+ GGGG GGG G W Sbjct: 331 GGGGRGGWGGGG--GGGGRGGGG-GGGGRGGWGGGGGGWGGGGGGGGGW----------- 376 Query: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY-DRGGYRGRG-GDRGGFR 495 GG GG GG G GGRGGY RGGY GRG GD G Sbjct: 377 -------------------GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417 Query: 496 GGRGGGDRGGFG 507 GG GGG GG G Sbjct: 418 GGGGGGGGGGGG 429 Score = 85.9 bits (211), Expect = 8e-17 Identities = 54/129 (41%), Positives = 66/129 (51%), Gaps = 19/129 (14%) Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191 + P + +Q+ G + + G G + G GG GGGGG +G GGG G Sbjct: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWG-------GGGGGG 373 Query: 192 GGYGNQDQSGGGGSGGY-GQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250 GG+G GGGG GG+ G+ D G GRGG GG GG GG GY +P G GGG GG Sbjct: 374 GGWGG---GGGGGRGGFQGRGDYG--GRGGYGGRGGYGGRGYG------DPYGGGGGGGG 422 Query: 251 RGGMGGSDR 259 GG GG R Sbjct: 423 GGGGGGGYR 431 Score = 73.6 bits (179), Expect = 4e-13 Identities = 45/89 (50%), Positives = 48/89 (53%), Gaps = 12/89 (13%) Query: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGG 246 GGG GG+G GGGG GG RGG G GG GG GGGGGG+ GG G GG Sbjct: 331 GGGGRGGWG-----GGGGGGG-----RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG-GG 379 Query: 247 GRGGRGG-MGGSDRGGFNKFGGPRDQGSR 274 G GGRGG G D GG +GG G R Sbjct: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/76 (51%), Positives = 39/76 (51%), Gaps = 8/76 (10%) Query: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258 Q GGGG RGG G GG GGG GGGGGG R G G GGG GG GG GG Sbjct: 329 QEGGGG--------RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380 Query: 259 RGGFNKFGGPRDQGSR 274 GG F G D G R Sbjct: 381 GGGRGGFQGRGDYGGR 396 Score = 57.8 bits (138), Expect = 2e-08 Identities = 32/54 (59%), Positives = 33/54 (61%), Gaps = 9/54 (16%) Query: 378 GGGNGRGG-------RGRGGPMGRGGYGGGGSGG--GGRGGFPSGGGGGGGQQR 422 GGG GRGG GRGG GRGGYGG G G GG GG GGGGGGG +R Sbjct: 379 GGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432 Score = 55.8 bits (133), Expect = 9e-08 Identities = 36/82 (43%), Positives = 42/82 (51%), Gaps = 10/82 (12%) Query: 445 NQCKAPKPDGP--------GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496 N+ + P P+ P GGG GG GG G R GG GG RGG+ G GG GG G Sbjct: 313 NEIEPPPPEMPPWQKRQEGGGGRGG-WGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371 Query: 497 GRGG-GDRGGFGPGKMDSRGEH 517 G GG G GG G G RG++ Sbjct: 372 GGGGWGGGGGGGRGGFQGRGDY 393 Score = 55.8 bits (133), Expect = 9e-08 Identities = 45/115 (39%), Positives = 47/115 (40%), Gaps = 50/115 (43%) Query: 403 GGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462 GGGGRGG+ GGGGGGG G GGG GG Sbjct: 331 GGGGRGGW--GGGGGGG----------------------------------GRGGGGGG- 353 Query: 463 HMGGNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGDRGGF-GPGKMDSRG 515 GGRGG+ GG G GG GG GG GGG RGGF G G RG Sbjct: 354 -----------GGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRG 397 Score = 49.3 bits (116), Expect = 9e-06 Identities = 31/66 (46%), Positives = 33/66 (50%), Gaps = 18/66 (27%) Query: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGG----------GGSGG-GGRGGF-------PSG 413 R + GGG GG G GG G GG GG GG GG GGRGG+ P G Sbjct: 356 RGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415 Query: 414 GGGGGG 419 GGGGGG Sbjct: 416 GGGGGG 421 Score = 40.0 bits (92), Expect = 0.005 Identities = 33/126 (26%), Positives = 41/126 (32%), Gaps = 21/126 (16%) Query: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128 Q +G G GG+G G G + G G +G G Sbjct: 326 QKRQEGGGGRGGWGGGG-------------GGGGRGGGGGGGGRGGWGGGGGGWGGGGGG 372 Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188 GG + + + Y GYG + Y G GGGGG G GG Sbjct: 373 GGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG--------GG 424 Query: 189 GSGGGY 194 G GGGY Sbjct: 425 GGGGGY 430 >gi|186928829 dermokine isoform 4 precursor [Homo sapiens] Length = 386 Score = 91.3 bits (225), Expect = 2e-18 Identities = 73/226 (32%), Positives = 95/226 (42%), Gaps = 28/226 (12%) Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126 ++GG+G S GQ PG P P +++GS+G + Q + +GQ P Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203 Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G+ +Q QP YG + S + NPP S SGGG GGG+ Q Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 S SSG GS G N SGG SG GG G SG GG G + SS G Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288 G GG GG G + G K G +GS Q++ + +F Sbjct: 312 SSSGNHGGSGG-GNGHKPGCEK-PGNEARGSGESGIQNSETSPGMF 355 Score = 66.2 bits (160), Expect = 7e-11 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%) Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427 G G GG+G+G P G G GY G +G G G P G GG GG G Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211 Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485 P ++ S +NE C P P G GGG G G G G G + G Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269 Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516 G G GG GG GG G G + DS E Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303 Score = 56.6 bits (135), Expect = 5e-08 Identities = 67/278 (24%), Positives = 97/278 (34%), Gaps = 39/278 (14%) Query: 43 QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98 +ST T+ G++ G + + G G + G+ G S Q ++ + G P Sbjct: 29 ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87 Query: 99 GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145 G+G A + G + ++ + GS+ P + G ++ G Sbjct: 88 GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147 Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198 + G G Q Q N G G G G++G + G G GG N + Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207 Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGG--GGGGGGYNRSSGGYEPRG---RGG 246 G GYG + G GSGGG GGG G S G G G Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267 Query: 247 GRGG--RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282 GG G G GG + GSR DS ++S Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305 Score = 52.8 bits (125), Expect = 8e-07 Identities = 52/175 (29%), Positives = 67/175 (38%), Gaps = 17/175 (9%) Query: 32 PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89 P+GQ G T+T G Q Y S S T P G G G S +S Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246 Query: 90 SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147 G QS G G + S+SG SSS SSS G S + GG + G + Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304 Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202 S +G +S + GG GGG G G ++ + G G N + S G Sbjct: 305 S------WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353 Score = 49.3 bits (116), Expect = 9e-06 Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 16/161 (9%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70 T + GA QPG G + S+Q G + SG G S +S G G G+QS Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252 Query: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQ-S 127 G GS G + SS S SS G SS + GS G S SS+G S Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312 Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168 S + S GG G ++ N +G G+ NS + G Sbjct: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353 Score = 43.5 bits (101), Expect = 5e-04 Identities = 79/359 (22%), Positives = 110/359 (30%), Gaps = 69/359 (19%) Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211 G+G + + G G GG G S ++ G G G + G G + G + Sbjct: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99 Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256 G +G G G G +G +E G G G +GG+GG Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159 Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316 +G G P G +S N G G N + TN + Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209 Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376 + R + + +G + PPS G SG Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247 Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 G +G G G G G GG S G GG SGG GG +G + + Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 SW + G G G GGN G + G ++ G RG G + Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQ 346 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%) Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414 GN G G +G P G+GG GG + G G PSG Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237 Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468 GGG G + N N + + GG GGS + GG+ Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297 Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505 GD G G G G GG G + G ++ G Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334 Score = 42.7 bits (99), Expect = 8e-04 Identities = 83/381 (21%), Positives = 120/381 (31%), Gaps = 51/381 (13%) Query: 78 TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136 +G G QS + S G G+G A S G + G S + Q Sbjct: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73 Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188 G +++ G P G+G + + G G G G+ + G Sbjct: 74 -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130 Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245 G G G + SGG G G Q GG+G+G GG G GY +S G Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189 Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302 G G+GG GG G N G G R ++ + N G G + + Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247 Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362 + ++G D G G ++ S+ + G SG Sbjct: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--SGG 295 Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422 +RG G G +GG G G G + G G G Sbjct: 296 -------------SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342 Query: 423 AGDWKC-PNPTCENMNFSWRN 442 +G +P N + W+N Sbjct: 343 SGIQNSETSPGMFNFDTFWKN 363 >gi|33504489 dermokine isoform 2 precursor [Homo sapiens] Length = 476 Score = 91.3 bits (225), Expect = 2e-18 Identities = 73/226 (32%), Positives = 95/226 (42%), Gaps = 28/226 (12%) Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126 ++GG+G S GQ PG P P +++GS+G + Q + +GQ P Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203 Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G+ +Q QP YG + S + NPP S SGGG GGG+ Q Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 S SSG GS G N SGG SG GG G SG GG G + SS G Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIF 288 G GG GG G + G K G +GS Q++ + +F Sbjct: 312 SSSGNHGGSGG-GNGHKPGCEK-PGNEARGSGESGIQNSETSPGMF 355 Score = 66.2 bits (160), Expect = 7e-11 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%) Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427 G G GG+G+G P G G GY G +G G G P G GG GG G Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211 Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485 P ++ S +NE C P P G GGG G G G G G + G Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269 Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516 G G GG GG GG G G + DS E Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303 Score = 56.6 bits (135), Expect = 5e-08 Identities = 67/278 (24%), Positives = 97/278 (34%), Gaps = 39/278 (14%) Query: 43 QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98 +ST T+ G++ G + + G G + G+ G S Q ++ + G P Sbjct: 29 ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87 Query: 99 GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145 G+G A + G + ++ + GS+ P + G ++ G Sbjct: 88 GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147 Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198 + G G Q Q N G G G G++G + G G GG N + Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207 Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGG--GGGGGGYNRSSGGYEPRG---RGG 246 G GYG + G GSGGG GGG G S G G G Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267 Query: 247 GRGG--RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282 GG G G GG + GSR DS ++S Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305 Score = 52.8 bits (125), Expect = 8e-07 Identities = 52/175 (29%), Positives = 67/175 (38%), Gaps = 17/175 (9%) Query: 32 PYGQQSYSGYSQ-STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQS 89 P+GQ G T+T G Q Y S S T P G G G S +S Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG-----GGSSNSGG 246 Query: 90 SYGQQSSYPGYGQQPAPS--STSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ 147 G QS G G + S+SG SSS SSS G S + GG + G + Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES 304 Query: 148 SYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202 S +G +S + GG GGG G G ++ + G G N + S G Sbjct: 305 S------WGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353 Score = 49.3 bits (116), Expect = 9e-06 Identities = 51/161 (31%), Positives = 66/161 (40%), Gaps = 16/161 (9%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQS 70 T + GA QPG G + S+Q G + SG G S +S G G G+QS Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEG-------CTNPPPSGSGGGSSNSGG-----GSGSQS 252 Query: 71 TPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSS--TSGSYGSSSQSSSYGQPQ-S 127 G GS G + SS S SS G SS + GS G S SS+G S Sbjct: 253 GSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312 Query: 128 GSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG 168 S + S GG G ++ N +G G+ NS + G Sbjct: 313 SSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPG 353 Score = 43.5 bits (101), Expect = 5e-04 Identities = 79/359 (22%), Positives = 110/359 (30%), Gaps = 69/359 (19%) Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211 G+G + + G G GG G S ++ G G G + G G + G + Sbjct: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99 Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256 G +G G G G +G +E G G G +GG+GG Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159 Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316 +G G P G +S N G G N + TN + Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209 Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376 + R + + +G + PPS G SG Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247 Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 G +G G G G G GG S G GG SGG GG +G + + Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 SW + G G G GGN G + G ++ G RG G + Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQ 346 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%) Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414 GN G G +G P G+GG GG + G G PSG Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237 Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468 GGG G + N N + + GG GGS + GG+ Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297 Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505 GD G G G G GG G + G ++ G Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334 Score = 42.7 bits (99), Expect = 8e-04 Identities = 83/381 (21%), Positives = 120/381 (31%), Gaps = 51/381 (13%) Query: 78 TGGYGSSQSSQSSYGQQSSYP-GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSY 136 +G G QS + S G G+G A S G + G S + Q Sbjct: 18 SGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQ---- 73 Query: 137 GGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGG--GGGGGNYGQDQSSMSSGG------ 188 G +++ G P G+G + + G G G G+ + G Sbjct: 74 -GTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRG 130 Query: 189 ---GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245 G G G + SGG G G Q GG+G+G GG G GY +S G Sbjct: 131 SWQGVPGHNGAWETSGGHGIFG-SQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQ 189 Query: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQG---SRHDSEQDNSDNNTIFVQGLGENVTIESVA 302 G G+GG GG G N G G R ++ + N G G + + Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGG-- 247 Query: 303 DYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGN 362 + ++G D G G ++ S+ + G SG Sbjct: 248 ----------SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGN--SGG 295 Query: 363 PIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422 +RG G G +GG G G G + G G G Sbjct: 296 -------------SRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342 Query: 423 AGDWKC-PNPTCENMNFSWRN 442 +G +P N + W+N Sbjct: 343 SGIQNSETSPGMFNFDTFWKN 363 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 91.3 bits (225), Expect = 2e-18 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%) Query: 23 QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74 Q QQ Q QQ S + G G + +G ++++ G Q+ P G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 75 YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114 G + G+ + +PG G QQP + G YG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177 Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156 S++ +S ++G Q +GGQQ + G S +P Q GY Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213 Q N Y S GGGGGGGGG GGGSGGG G GG G+GG G Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281 Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259 + GGGGGGGY SS GY PR +GGG G GG G GS Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 Query: 260 GGFNKFGGPRDQGS 273 GGF +F G S Sbjct: 342 GGFQRFAGQNQHPS 355 Score = 53.1 bits (126), Expect = 6e-07 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435 N G R G G GG G GG GGGGSGGGG GG GG G G A Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284 Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 A G GGG GGS G R GG G GG Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333 Query: 496 GGRGGGDRGGF 506 G GGF Sbjct: 334 KAAAGSAAGGF 344 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%) Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419 ++R G G GG G GG G GG GGGG G G G +GGGGGGG Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299 Score = 46.6 bits (109), Expect = 6e-05 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85 SQ QP G QS ++S + S S Q + GTQ PQ Sbjct: 704 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 743 Query: 86 SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145 + YG Q + P P+P + SS Q S+ SG+Y G Q YG Sbjct: 744 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 791 Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199 Q +Y+ P Y + S G G G N +GQ S ++ G G N+ Sbjct: 792 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 851 Query: 200 SGGGGS---GGYGQQDRGGRGRG 219 G S G +GG G G Sbjct: 852 PGNMSSMTPSSPGMSQQGGPGMG 874 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%) Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438 G GGP GR G GG G G S G + D +N + Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230 Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494 + N +CN G GGG GG GG GG GG GG G GG G Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283 Query: 495 --------RGGRGGGDRGGFGPG 509 GG GGG GG G Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306 Score = 45.8 bits (107), Expect = 1e-04 Identities = 74/289 (25%), Positives = 91/289 (31%), Gaps = 59/289 (20%) Query: 6 YTQQATQSYGAYPTQPGQ---------GYSQQSSQPYGQQSYSGY-SQSTDTSGYGQSSY 55 Y QQ Q Y + QP SQQ QP S GY ++S G+ ++ Sbjct: 547 YCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH 606 Query: 56 SSY---------------GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQ------ 94 G + GT++T S G SSQ QS+ Q Sbjct: 607 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 666 Query: 95 ----SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYN 150 SS PG P+PS GS+ S P S SQ P QS + S + Sbjct: 667 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS---ESSSH 720 Query: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS------MSSGGGSGGGYGNQDQSGGGG 204 P Q G YG Q+ S GG G + QS G Sbjct: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780 Query: 205 SGG-----YGQQDRGGRGRGGSG-------GGGGGGGGGYNRSSGGYEP 241 + G YG Q R SG G G G G N G P Sbjct: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGP 829 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%) Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191 QQ + QQQ QQQ Q QQ+ ++++ GG GGG G D GG Sbjct: 50 QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106 Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226 G Q G G G+ + G G G+ GGGG Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 +N G P GG GGR G GG Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199 Score = 40.4 bits (93), Expect = 0.004 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%) Query: 21 PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78 PG G + + S S G + +G Q+ G G ++ G+ Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 79 GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124 G Q+S Y Q + YPGY + A G G S G Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279 Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179 + + + + GG YG + GYG + GG G GGGG + + Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334 Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201 + ++GG NQ SG Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356 Score = 39.7 bits (91), Expect = 0.007 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%) Query: 4 NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55 N+Y A + G + G + Q Q Q G S + G Q+S+ Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229 Query: 56 SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Y SQ Y S P G GG G G G G A + +G+ + Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283 Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170 ++ +++ G YGG YG +QQ G G + S G Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339 Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200 GG GQ+Q M S GGS Y + Q Q+ Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399 Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223 G+ GQQ G G G G Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422 Score = 38.1 bits (87), Expect = 0.020 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%) Query: 4 NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61 N T A G + P G+ + + P+G + G S+ T G +S + Sbjct: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1253 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 Q+ + G YG+S + YGQQ YPG G S Sbjct: 1254 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1298 Query: 121 SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170 YG Q G Y QQP+Y YG + YN QQ YN G G Sbjct: 1299 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1355 Score = 37.4 bits (85), Expect = 0.034 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410 GGG G GG G GG G GG G G +GGGG GG+ Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316 Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437 P GGG GG Q+ AG + P+ +N Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Score = 33.5 bits (75), Expect = 0.49 Identities = 37/150 (24%), Positives = 45/150 (30%), Gaps = 23/150 (15%) Query: 15 GAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST--- 71 G+ P Q S YG Y G + Y Q Q++G T Sbjct: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533 Query: 72 --PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129 P YG G S Y QQ P Y QQP P + P Sbjct: 534 LMPPQYGQQG--------VSGYCQQGQQPYYSQQPQPPHL--------PPQAQYLPSQSQ 577 Query: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQN 159 QP Q+ YG + PP G+ N Sbjct: 578 QRYQPQQDMSQEGYGTRS--QPPLAPGKPN 605 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 22 GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76 GQG SQ + P G+ +G + SS G SQ G G + + Sbjct: 826 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 885 Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135 ++ S+ +Q S+PG Q +S+S + SSS Q+ YS P+ Sbjct: 886 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 944 Score = 32.0 bits (71), Expect = 1.4 Identities = 45/190 (23%), Positives = 57/190 (30%), Gaps = 19/190 (10%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60 A + G + GQ + P Q + S + G YSS Q Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396 Query: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113 SQ G + Q + G G +Q + QQ S+P + S Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456 Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 GS +PQ P QQ S SY PP G Q G G Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513 Query: 174 GGNYGQDQSS 183 G Y Q Q S Sbjct: 514 GMQYPQQQDS 523 Score = 30.8 bits (68), Expect = 3.2 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%) Query: 25 YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80 YS Q + Y Q S YS GQ Y Y + + G G T PQ G Sbjct: 1338 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1391 Query: 81 YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129 G QSS S QQ+ + P P G +Q+ Y + Sbjct: 1392 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1450 Query: 130 YSQQPSYGGQQQSY-----GQQQSYNPPQ 153 SQ PS+ Q+Q Y Q PPQ Sbjct: 1451 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1479 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 91.3 bits (225), Expect = 2e-18 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%) Query: 23 QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74 Q QQ Q QQ S + G G + +G ++++ G Q+ P G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 75 YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114 G + G+ + +PG G QQP + G YG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177 Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156 S++ +S ++G Q +GGQQ + G S +P Q GY Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213 Q N Y S GGGGGGGGG GGGSGGG G GG G+GG G Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281 Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259 + GGGGGGGY SS GY PR +GGG G GG G GS Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 Query: 260 GGFNKFGGPRDQGS 273 GGF +F G S Sbjct: 342 GGFQRFAGQNQHPS 355 Score = 53.1 bits (126), Expect = 6e-07 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435 N G R G G GG G GG GGGGSGGGG GG GG G G A Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284 Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 A G GGG GGS G R GG G GG Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333 Query: 496 GGRGGGDRGGF 506 G GGF Sbjct: 334 KAAAGSAAGGF 344 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%) Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419 ++R G G GG G GG G GG GGGG G G G +GGGGGGG Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299 Score = 46.6 bits (109), Expect = 6e-05 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85 SQ QP G QS ++S + S S Q + GTQ PQ Sbjct: 691 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 730 Query: 86 SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145 + YG Q + P P+P + SS Q S+ SG+Y G Q YG Sbjct: 731 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 778 Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199 Q +Y+ P Y + S G G G N +GQ S ++ G G N+ Sbjct: 779 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 838 Query: 200 SGGGGS---GGYGQQDRGGRGRG 219 G S G +GG G G Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMG 861 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%) Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438 G GGP GR G GG G G S G + D +N + Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230 Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494 + N +CN G GGG GG GG GG GG GG G GG G Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283 Query: 495 --------RGGRGGGDRGGFGPG 509 GG GGG GG G Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306 Score = 44.7 bits (104), Expect = 2e-04 Identities = 81/313 (25%), Positives = 92/313 (29%), Gaps = 80/313 (25%) Query: 1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPY-----------------GQQSYSGYSQ 43 MA Y QQ Q Y Q GY QQ QPY QS Y Sbjct: 512 MAGMQYPQQ--QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP 569 Query: 44 STDTS--GYGQSSYSSY-------------------------GQSQNTGYGTQSTPQGYG 76 D S GYG S G + GT++T Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629 Query: 77 STGGYGSSQSSQSSYGQQ----------SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126 S G SSQ QS+ Q SS PG P+PS GS+ S P Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPA 686 Query: 127 SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS--- 183 S SQ P QS + S +P Q G YG Q+ Sbjct: 687 SIPGSQMPPQPPGSQS---ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743 Query: 184 ---MSSGGGSGGGYGNQDQSGGGGSGG-----YGQQDRGGRGRGGSG-------GGGGGG 228 S GG G + QS G+ G YG Q R SG G G G Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803 Query: 229 GGGYNRSSGGYEP 241 G N G P Sbjct: 804 GISANNQMHGQGP 816 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%) Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191 QQ + QQQ QQQ Q QQ+ ++++ GG GGG G D GG Sbjct: 50 QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106 Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226 G Q G G G+ + G G G+ GGGG Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 +N G P GG GGR G GG Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199 Score = 40.4 bits (93), Expect = 0.004 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%) Query: 21 PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78 PG G + + S S G + +G Q+ G G ++ G+ Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 79 GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124 G Q+S Y Q + YPGY + A G G S G Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279 Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179 + + + + GG YG + GYG + GG G GGGG + + Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334 Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201 + ++GG NQ SG Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356 Score = 39.7 bits (91), Expect = 0.007 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%) Query: 4 NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55 N+Y A + G + G + Q Q Q G S + G Q+S+ Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229 Query: 56 SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Y SQ Y S P G GG G G G G A + +G+ + Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283 Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170 ++ +++ G YGG YG +QQ G G + S G Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339 Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200 GG GQ+Q M S GGS Y + Q Q+ Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399 Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223 G+ GQQ G G G G Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422 Score = 38.1 bits (87), Expect = 0.020 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%) Query: 4 NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61 N T A G + P G+ + + P+G + G S+ T G +S + Sbjct: 1234 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1293 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 Q+ + G YG+S + YGQQ YPG G S Sbjct: 1294 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1338 Query: 121 SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170 YG Q G Y QQP+Y YG + YN QQ YN G G Sbjct: 1339 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1395 Score = 37.4 bits (85), Expect = 0.034 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410 GGG G GG G GG G GG G G +GGGG GG+ Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316 Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437 P GGG GG Q+ AG + P+ +N Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Score = 35.0 bits (79), Expect = 0.17 Identities = 49/206 (23%), Positives = 61/206 (29%), Gaps = 19/206 (9%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60 A + G + GQ + P Q + S + G YSS Q Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396 Query: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113 SQ G + Q + G G +Q + QQ S+P + S Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456 Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 GS +PQ P QQ S SY PP G Q G G Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513 Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQ 199 G Y Q Q G GY Q Q Sbjct: 514 GMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Score = 33.5 bits (75), Expect = 0.49 Identities = 42/169 (24%), Positives = 54/169 (31%), Gaps = 38/169 (22%) Query: 18 PTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST------ 71 P+QP + + GQQ+ +G D ++ ++ +Q + S Sbjct: 392 PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT 451 Query: 72 ----------------PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG---- 111 PQ YG G SQ QSS SY G Q P G Sbjct: 452 MGRSQGSPMDPMVMKRPQLYGM-GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510 Query: 112 -----SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQS--YNPPQ 153 Y YGQ Y QQ GQQ Y QQ + PPQ Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGYCQQ----GQQPYYSQQPQPPHLPPQ 555 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 22 GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76 GQG SQ + P G+ +G + SS G SQ G G + + Sbjct: 813 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872 Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135 ++ S+ +Q S+PG Q +S+S + SSS Q+ YS P+ Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 931 Score = 30.8 bits (68), Expect = 3.2 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%) Query: 25 YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80 YS Q + Y Q S YS GQ Y Y + + G G T PQ G Sbjct: 1378 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1431 Query: 81 YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129 G QSS S QQ+ + P P G +Q+ Y + Sbjct: 1432 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1490 Query: 130 YSQQPSYGGQQQSY-----GQQQSYNPPQ 153 SQ PS+ Q+Q Y Q PPQ Sbjct: 1491 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1519 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 91.3 bits (225), Expect = 2e-18 Identities = 95/314 (30%), Positives = 120/314 (38%), Gaps = 79/314 (25%) Query: 23 QGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS--------YSSYGQSQNTGYGTQSTPQG 74 Q QQ Q QQ S + G G + +G ++++ G Q+ P G Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117 Query: 75 YGSTGGYGSSQSSQSSYGQQSS----YPGYG----QQPAPSSTSGS------------YG 114 G + G+ + +PG G QQP + G YG Sbjct: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG 177 Query: 115 SSSQSSSYGQPQSGSYSQQPSYGGQQQ------------SYGQQQSYNPPQ----GY--G 156 S++ +S ++G Q +GGQQ + G S +P Q GY Sbjct: 178 SAAPASGGPGGRAGPCFDQ--HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235 Query: 157 QQNQYNSSS---GGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213 Q N Y S GGGGGGGGG GGGSGGG G GG G+GG G Sbjct: 236 QCNHYPGYSRPGAGGGGGGGGG----------GGGGSGGGGG----GGGAGAGGAGAGAV 281 Query: 214 GGRGRGGSGGGGGGGGGGYNRSSGGY----EPRGRGGG-RGGRGGMG---------GSDR 259 + GGGGGGGY SS GY PR +GGG G GG G GS Sbjct: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341 Query: 260 GGFNKFGGPRDQGS 273 GGF +F G S Sbjct: 342 GGFQRFAGQNQHPS 355 Score = 53.1 bits (126), Expect = 6e-07 Identities = 45/131 (34%), Positives = 45/131 (34%), Gaps = 24/131 (18%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCEN 435 N G R G G GG G GG GGGGSGGGG GG GG G G A Sbjct: 238 NHYPGYSRPGAGGGG--GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAA----------- 284 Query: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFR 495 A G GGG GGS G R GG G GG Sbjct: 285 --------AAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG---PGGGGAASLS 333 Query: 496 GGRGGGDRGGF 506 G GGF Sbjct: 334 KAAAGSAAGGF 344 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/57 (43%), Positives = 28/57 (49%), Gaps = 12/57 (21%) Query: 375 FNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGG------------FPSGGGGGGG 419 ++R G G GG G GG G GG GGGG G G G +GGGGGGG Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299 Score = 46.6 bits (109), Expect = 6e-05 Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 41/203 (20%) Query: 26 SQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQ 85 SQ QP G QS ++S + S S Q + GTQ PQ Sbjct: 691 SQMPPQPPGSQS--------ESSSHPALSQSPMPQERGFMAGTQRNPQ------------ 730 Query: 86 SSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQ 145 + YG Q + P P+P + SS Q S+ SG+Y G Q YG Sbjct: 731 --MAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN----SSGTY------GPQMSQYGP 778 Query: 146 QQSYNPPQGYGQQNQYNSSSGGGGGGGGGGN--YGQDQS----SMSSGGGSGGGYGNQDQ 199 Q +Y+ P Y + S G G G N +GQ S ++ G G N+ Sbjct: 779 QGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPF 838 Query: 200 SGGGGS---GGYGQQDRGGRGRG 219 G S G +GG G G Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMG 861 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/143 (30%), Positives = 49/143 (34%), Gaps = 28/143 (19%) Query: 382 GRGGRGRGGPMGRGGY---GGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNF 438 G GGP GR G GG G G S G + D +N + Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD------PLQNSHE 230 Query: 439 SWRN-ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF--- 494 + N +CN G GGG GG GG GG GG GG G GG G Sbjct: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGGG-------GGSGGGGGGGGAGAGGAGAGAVAA 283 Query: 495 --------RGGRGGGDRGGFGPG 509 GG GGG GG G Sbjct: 284 AAAAAAAAAGGGGGGGYGGSSAG 306 Score = 44.7 bits (104), Expect = 2e-04 Identities = 81/313 (25%), Positives = 92/313 (29%), Gaps = 80/313 (25%) Query: 1 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPY-----------------GQQSYSGYSQ 43 MA Y QQ Q Y Q GY QQ QPY QS Y Sbjct: 512 MAGMQYPQQ--QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP 569 Query: 44 STDTS--GYGQSSYSSY-------------------------GQSQNTGYGTQSTPQGYG 76 D S GYG S G + GT++T Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629 Query: 77 STGGYGSSQSSQSSYGQQ----------SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQ 126 S G SSQ QS+ Q SS PG P+PS GS+ S P Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPA 686 Query: 127 SGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSS--- 183 S SQ P QS + S +P Q G YG Q+ Sbjct: 687 SIPGSQMPPQPPGSQS---ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743 Query: 184 ---MSSGGGSGGGYGNQDQSGGGGSGG-----YGQQDRGGRGRGGSG-------GGGGGG 228 S GG G + QS G+ G YG Q R SG G G G Sbjct: 744 SPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGM 803 Query: 229 GGGYNRSSGGYEP 241 G N G P Sbjct: 804 GISANNQMHGQGP 816 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 30/155 (19%) Query: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191 QQ + QQQ QQQ Q QQ+ ++++ GG GGG G D GG Sbjct: 50 QQLNQFQQQQQQQQQQQQQQQQ---QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKD 106 Query: 192 GGYGNQDQSGGG----------------GSGGYGQQDRGGRGRGGS---------GGGGG 226 G Q G G G+ + G G G+ GGGG Sbjct: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166 Query: 227 GGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261 +N G P GG GGR G GG Sbjct: 167 AAVPEFNNYYGSAAP--ASGGPGGRAGPCFDQHGG 199 Score = 40.4 bits (93), Expect = 0.004 Identities = 45/202 (22%), Positives = 67/202 (33%), Gaps = 26/202 (12%) Query: 21 PGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQ--STPQGYGST 78 PG G + + S S G + +G Q+ G G ++ G+ Sbjct: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219 Query: 79 GGYGSSQSSQSSY--GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ------------ 124 G Q+S Y Q + YPGY + A G G S G Sbjct: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279 Query: 125 --PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGG---GGGGGGGGNYGQ 179 + + + + GG YG + GYG + GG G GGGG + + Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSA-----GYGVLSSPRQQGGGMMMGPGGGGAASLSK 334 Query: 180 DQSSMSSGGGSGGGYGNQDQSG 201 + ++GG NQ SG Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSG 356 Score = 39.7 bits (91), Expect = 0.007 Identities = 61/263 (23%), Positives = 83/263 (31%), Gaps = 56/263 (21%) Query: 4 NDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG--------QSSY 55 N+Y A + G + G + Q Q Q G S + G Q+S+ Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQ---QSPGMGMMHSASAAAAGAPGSMDPLQNSH 229 Query: 56 SSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Y SQ Y S P G GG G G G G A + +G+ + Sbjct: 230 EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG------GGGGAGAGGAGAGAVAA 283 Query: 116 SSQSSSYGQPQSGSYSQQPSYGGQQQSYG-----QQQSYNPPQGYGQQNQYNSSSGGGGG 170 ++ +++ G YGG YG +QQ G G + S G Sbjct: 284 AAAAAAAAAGGGGG----GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339 Query: 171 GGGGGNY--GQDQSS-----------------MSSGGGSGGGYGN-----------QDQS 200 GG GQ+Q M S GGS Y + Q Q+ Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399 Query: 201 GGGGSGGYGQQDRGGRGRGGSGG 223 G+ GQQ G G G G Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMG 422 Score = 38.1 bits (87), Expect = 0.020 Identities = 46/177 (25%), Positives = 61/177 (34%), Gaps = 25/177 (14%) Query: 4 NDYTQQATQSYG-AYPTQPGQGYSQQSSQPYG-QQSYSGYSQSTDTSGYGQSSYSSYGQS 61 N T A G + P G+ + + P+G + G S+ T G +S + Sbjct: 1181 NSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYN 1240 Query: 62 QNTGYGTQSTPQGYGSTGGYGSSQSSQSS-YGQQSSYPGYGQQPAPSSTSGSYGSSSQSS 120 Q+ + G YG+S + YGQQ YPG G S Sbjct: 1241 QSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQ--YPGQGPP-------------SGQP 1285 Query: 121 SYGQPQSGSYSQQPSYGGQQQS-YG------QQQSYNPPQGYGQQNQYNSSSGGGGG 170 YG Q G Y QQP+Y YG + YN QQ YN G G Sbjct: 1286 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1342 Score = 37.4 bits (85), Expect = 0.034 Identities = 31/106 (29%), Positives = 37/106 (34%), Gaps = 46/106 (43%) Query: 378 GGGNGRGGRGRGGPMGRGGYGGGG-----------SGGGGRGGF---------------- 410 GGG G GG G GG G GG G G +GGGG GG+ Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQ 316 Query: 411 -------PSGGGG------------GGGQQRAGDWKCPNPTCENMN 437 P GGG GG Q+ AG + P+ +N Sbjct: 317 GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN 362 Score = 35.0 bits (79), Expect = 0.17 Identities = 49/206 (23%), Positives = 61/206 (29%), Gaps = 19/206 (9%) Query: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYG---------Q 60 A + G + GQ + P Q + S + G YSS Q Sbjct: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396 Query: 61 SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYG-------QQSSYPGYGQQPAPSSTSGSY 113 SQ G + Q + G G +Q + QQ S+P + S Sbjct: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456 Query: 114 GSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173 GS +PQ P QQ S SY PP G Q G G Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTPGAMA 513 Query: 174 GGNYGQDQSSMSSGGGSGGGYGNQDQ 199 G Y Q Q G GY Q Q Sbjct: 514 GMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Score = 33.5 bits (75), Expect = 0.49 Identities = 42/169 (24%), Positives = 54/169 (31%), Gaps = 38/169 (22%) Query: 18 PTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST------ 71 P+QP + + GQQ+ +G D ++ ++ +Q + S Sbjct: 392 PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT 451 Query: 72 ----------------PQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSG---- 111 PQ YG G SQ QSS SY G Q P G Sbjct: 452 MGRSQGSPMDPMVMKRPQLYGM-GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG 510 Query: 112 -----SYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQS--YNPPQ 153 Y YGQ Y QQ GQQ Y QQ + PPQ Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGYCQQ----GQQPYYSQQPQPPHLPPQ 555 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 22 GQGYSQQ-SSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGT----QSTPQGYG 76 GQG SQ + P G+ +G + SS G SQ G G + + Sbjct: 813 GQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872 Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPS 135 ++ S+ +Q S+PG Q +S+S + SSS Q+ YS P+ Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPA 931 Score = 30.8 bits (68), Expect = 3.2 Identities = 41/149 (27%), Positives = 51/149 (34%), Gaps = 27/149 (18%) Query: 25 YSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQST----PQGYGSTGG 80 YS Q + Y Q S YS GQ Y Y + + G G T PQ G Sbjct: 1325 YSSQQQEMYNQYGGS-YSGPDRRPIQGQYPYP-YSRERMQGPGQIQTHGIPPQMMG---- 1378 Query: 81 YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY-----------GQPQSGS 129 G QSS S QQ+ + P P G +Q+ Y + Sbjct: 1379 -GPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINH 1437 Query: 130 YSQQPSYGGQQQSY-----GQQQSYNPPQ 153 SQ PS+ Q+Q Y Q PPQ Sbjct: 1438 ESQWPSHVSQRQPYMSSSASMQPITRPPQ 1466 >gi|186928827 dermokine isoform 5 precursor [Homo sapiens] Length = 398 Score = 90.9 bits (224), Expect = 3e-18 Identities = 67/198 (33%), Positives = 83/198 (41%), Gaps = 26/198 (13%) Query: 77 STGGYGSSQSSQSSYGQQSSYPGYGQQP----APSSTSGSYGSSSQSSSYGQ------PQ 126 ++GG+G S GQ PG P P +++GS+G + Q + +GQ P Sbjct: 144 TSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPN 203 Query: 127 SGSYSQ----QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 G+ +Q QP YG + S + NPP S SGGG GGG+ Q Sbjct: 204 FGTNTQGAVAQPGYGSVRASNQNEGCTNPPP---------SGSGGGSSNSGGGSGSQ--- 251 Query: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 S SSG GS G N SGG SG GG G SG GG G + SS G Sbjct: 252 SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 243 GRGGGRGGRGGMGGSDRG 260 G GG GG G G Sbjct: 312 SSSGNHGGSGGGNGHKPG 329 Score = 74.3 bits (181), Expect = 3e-13 Identities = 73/246 (29%), Positives = 87/246 (35%), Gaps = 39/246 (15%) Query: 15 GAYPTQPGQGYSQQSSQPYGQ-QSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQ 73 GA+ T G G GQ Q G + GY +S S+G + Q P Sbjct: 140 GAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNP------QGAPW 193 Query: 74 GYGSTGGYGS-SQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQ 132 G G GG + ++Q + Q PGYG A + G S G SG S Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQ----PGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249 Query: 133 QPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGG 192 S S G + + G SSSG GG SSGG SGG Sbjct: 250 SQSGSSGSGSNGDNNNGSSSGG--------SSSGSSSGG-------------SSGGSSGG 288 Query: 193 GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP--RGRGGGRGG 250 GN GG G G + G G S G GG GGG G +P RG G G Sbjct: 289 SSGN----SGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344 Query: 251 RGGMGG 256 G G Sbjct: 345 IQGFRG 350 Score = 66.2 bits (160), Expect = 7e-11 Identities = 69/284 (24%), Positives = 92/284 (32%), Gaps = 51/284 (17%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQST-DTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGG 80 G+ +++ G + Q T + G G +G + G G+TG Sbjct: 52 GKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGH 111 Query: 81 YGSSQS-------SQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQ 133 Q+ + + G PG+ S G +GS GQ G Sbjct: 112 EIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTP 171 Query: 134 PSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS----------- 182 +G S G +G Q + G GG GG N+G + Sbjct: 172 WVHGYPGNSAGS---------FGMNPQ--GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSV 220 Query: 183 --------------SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRG-----GSGG 223 S S GG S G G+ QSG GSG G + G G SGG Sbjct: 221 RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG 280 Query: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267 GG GG + +SGG RG G G GS G GG Sbjct: 281 SSGGSSGGSSGNSGG--SRGDSGSESSWGSSTGSSSGNHGGSGG 322 Score = 66.2 bits (160), Expect = 7e-11 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 17/154 (11%) Query: 378 GGGNGRGGRGRGGPMGRG-----GYGGGGSGGGGRG--GFPSGGGGGGGQQRAG---DWK 427 G G GG+G+G P G G GY G +G G G P G GG GG G Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211 Query: 428 CPNPTCENMNFSWRNECNQCKAPKPDGPGGGPG--GSHMGGNYGDDRRGGRGGYDRGGYR 485 P ++ S +NE C P P G GGG G G G G G + G Sbjct: 212 VAQPGYGSVRASNQNE--GCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSS 269 Query: 486 G---RGGDRGGFRGGRGGGDRGGFGPGKMDSRGE 516 G G GG GG GG G G + DS E Sbjct: 270 GGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303 Score = 59.7 bits (143), Expect = 6e-09 Identities = 65/278 (23%), Positives = 95/278 (34%), Gaps = 39/278 (14%) Query: 43 QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSS---QSSQSSYGQQ-SSYP 98 +ST T+ G++ G + + G G + G+ G S Q ++ + G P Sbjct: 29 ESTGTN-IGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVP 87 Query: 99 GYGQQPAPSSTSGSYGSSSQSSSY-------------GQPQSGSYSQQPSYGGQQQSYGQ 145 G+G A + G + ++ + GS+ P + G ++ G Sbjct: 88 GFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGG 147 Query: 146 QQSYNPPQGYGQQNQYNSSSGG-----GGGGGGGGNYGQDQSSMSSGGGSGGGYGN--QD 198 + G G Q Q N G G G G++G + G G GG N + Sbjct: 148 HGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTN 207 Query: 199 QSGGGGSGGYGQQDRGGRGRG-------GSGGGGGGGGGGYNRSSG-------GYEPRGR 244 G GYG + G GSGGG GGG SG G G Sbjct: 208 TQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGS 267 Query: 245 GGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNS 282 G G G GG + GSR DS ++S Sbjct: 268 SSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESS 305 Score = 50.4 bits (119), Expect = 4e-06 Identities = 83/365 (22%), Positives = 114/365 (31%), Gaps = 69/365 (18%) Query: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQS-SMSSGGGSGGGYGNQDQSGGGGSGGYGQQ- 211 G+G + + G G GG G S ++ G G G + G G + G + Sbjct: 40 GHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRV 99 Query: 212 DRGGRGRGGSGGGGG---------------GGGGGYNRSSGGYEPRGRGGGRGGRGGMGG 256 G +G G G G +G +E G G G +GG+GG Sbjct: 100 GEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGG 159 Query: 257 SDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKK 316 +G G P G +S N G G N + TN + Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFG----------TNTQ 209 Query: 317 TGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN 376 + R + + +G + PPS G SG Sbjct: 210 GAVAQPGYGSVRASNQNEG----CTNPPPSGSGG-----GSSNSGG-------------G 247 Query: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436 G +G G G G G GG S G GG SGG GG +G + + Sbjct: 248 SGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGG-SSGGSSGGSSGNSGGSRGDS----GS 302 Query: 437 NFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496 SW + G G G GGN G + G ++ G RG G +G Sbjct: 303 ESSWGSS---------TGSSSGNHGGSGGGN------GHKPGCEKPGNEARGSGESGIQG 347 Query: 497 GRGGG 501 RG G Sbjct: 348 FRGQG 352 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 31/157 (19%) Query: 380 GNGRGGRG---RGGPMGRGGYGGGGSGGGGRGGF----------------------PSGG 414 GN G G +G P G+GG GG + G G PSG Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237 Query: 415 GGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS------HMGGNY 468 GGG G + N N + + GG GGS + GG+ Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297 Query: 469 GDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGG 505 GD G G G G GG G + G ++ G Sbjct: 298 GDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPG 334 Score = 39.7 bits (91), Expect = 0.007 Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 29/183 (15%) Query: 11 TQSYGAYPTQPGQGYSQQSSQPYG----QQSYSGYSQSTDTSGYG-QSSYSSYGQSQNTG 65 T + GA QPG G + S+Q G S SG S G G QS S G + + Sbjct: 206 TNTQGAV-AQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNN 264 Query: 66 YGTQSTPQGYGST-GGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQ 124 G+ S GS+ GG S SS ++ GS G S SS+G Sbjct: 265 NGSSSGGSSSGSSSGGSSGGSSGGSS----------------GNSGGSRGDSGSESSWG- 307 Query: 125 PQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184 S + S ++GG G + P G + + + SG G G G + S Sbjct: 308 --SSTGSSSGNHGGSGGGNGHKPGCEKP---GNEARGSGESGIQGFRGQGVSSNMRNSET 362 Query: 185 SSG 187 S G Sbjct: 363 SPG 365 >gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform B1 [Homo sapiens] Length = 353 Score = 89.7 bits (221), Expect = 6e-18 Identities = 76/240 (31%), Positives = 103/240 (42%), Gaps = 52/240 (21%) Query: 287 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD-PP 345 +FV G+ E+ + DYF++ G I T I + TDR++GK +G V+FDD P Sbjct: 114 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 165 Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGR-GRGGPMGRGGYGGGGS 402 K + + +G+ +V A R + + +GRGG G G G GG G G Sbjct: 166 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGP 223 Query: 403 GG---GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459 G GG G+ SG G G G +G GGGP Sbjct: 224 GSNFRGGSDGYGSGRGFGDGY--------------------------------NGYGGGP 251 Query: 460 GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQ 519 GG + GG+ G GGRGGY GG G G GG+ GG G +G G + G + Q Sbjct: 252 GGGNFGGSPG--YGGGRGGYGGGG-PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQ 308 Score = 75.5 bits (184), Expect = 1e-13 Identities = 53/130 (40%), Positives = 61/130 (46%), Gaps = 21/130 (16%) Query: 157 QQNQYNSSSGGGGGG-----GGGGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGG 207 Q+ Q + S GG G GGGGN+G S GG GSG G+G+ GGG GG Sbjct: 194 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG 253 Query: 208 --YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265 +G G G GG GG GGGG GY GGY GGG GG G G +N F Sbjct: 254 GNFG----GSPGYGGGRGGYGGGGPGYGNQGGGY-----GGGYDNYGG-GNYGSGNYNDF 303 Query: 266 GGPRDQGSRH 275 G Q S + Sbjct: 304 GNYNQQPSNY 313 Score = 70.5 bits (171), Expect = 4e-12 Identities = 58/173 (33%), Positives = 69/173 (39%), Gaps = 25/173 (14%) Query: 103 QPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYN 162 Q SS SG G+ +G + G + P G + G Y +G+G + YN Sbjct: 194 QEVQSSRSGRGGNFG----FGDSRGGGGNFGPGPGSNFR--GGSDGYGSGRGFG--DGYN 245 Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222 GG GGG GG+ G GGG G GYGNQ GGG GGY G G G Sbjct: 246 GYGGGPGGGNFGGSPGYGGGRGGYGGG-GPGYGNQ---GGGYGGGYDNY-----GGGNYG 296 Query: 223 GGGGGGGGGYNRSSGGYEPRGRG--------GGRGGRGGMGGSDRGGFNKFGG 267 G G YN+ Y P G GG G G G GG +GG Sbjct: 297 SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349 Score = 70.1 bits (170), Expect = 5e-12 Identities = 55/161 (34%), Positives = 62/161 (38%), Gaps = 18/161 (11%) Query: 118 QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177 QSS G+ + + GG GYG + G GGG GGGN+ Sbjct: 197 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNF 256 Query: 178 GQDQSSMSSGGGSGG------GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231 G S GGG GG GYGNQ GGG GGY G G G G G Sbjct: 257 G---GSPGYGGGRGGYGGGGPGYGNQ---GGGYGGGYDNY-----GGGNYGSGNYNDFGN 305 Query: 232 YNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272 YN+ Y P + G GG MGG GG GG G Sbjct: 306 YNQQPSNYGPM-KSGNFGGSRNMGGPYGGGNYGPGGSGGSG 345 Score = 65.9 bits (159), Expect = 9e-11 Identities = 46/115 (40%), Positives = 54/115 (46%), Gaps = 18/115 (15%) Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGR 216 + + SS G GG G G+ S GG G G G+ + GGS GYG G Sbjct: 192 EMQEVQSSRSGRGGNFGFGD------SRGGGGNFGPGPGSNFR---GGSDGYGSGRGFGD 242 Query: 217 GRGGSGGGGGGG--GG--GYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267 G G GGG GGG GG GY GGY GGG G G GG GG++ +GG Sbjct: 243 GYNGYGGGPGGGNFGGSPGYGGGRGGY-----GGGGPGYGNQGGGYGGGYDNYGG 292 Score = 65.9 bits (159), Expect = 9e-11 Identities = 66/200 (33%), Positives = 79/200 (39%), Gaps = 53/200 (26%) Query: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128 QS+ G G G+G S+ ++G PG P + GS G S +G +G Sbjct: 197 QSSRSGRGGNFGFGDSRGGGGNFG-----PG----PGSNFRGGSDGYGS-GRGFGDGYNG 246 Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188 Y P G ++G Y GGG GG GGG G + GG Sbjct: 247 -YGGGPGGG----NFGGSPGY----------------GGGRGGYGGGGPGYG----NQGG 281 Query: 189 GSGGGYGNQDQSGGG--GSGGYG-------QQDRGGRGRGGSGGGGGGGGGGYNRSSGGY 239 G GGGY D GGG GSG Y Q G + G+ GG GG Y G Y Sbjct: 282 GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY--GGGNY 336 Query: 240 EPRGRGGGRGGRGGMGGSDR 259 P GG GG GG GG R Sbjct: 337 GP----GGSGGSGGYGGRSR 352 Score = 62.4 bits (150), Expect = 1e-09 Identities = 51/171 (29%), Positives = 65/171 (38%), Gaps = 26/171 (15%) Query: 43 QSTDTSGYGQSSYSSYGQSQNTG--YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100 Q +S G+ +G S+ G +G G + GYGS + G Y GY Sbjct: 194 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGR------GFGDGYNGY 247 Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ----SYNPPQGYG 156 G P + GS G YG G +Q YGG +YG +YN Y Sbjct: 248 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYN 307 Query: 157 QQ-NQYNSSSGGGGGGG-------GGGNYGQDQSSMSSGGGSGGGYGNQDQ 199 QQ + Y G GG GGGNYG G G GGYG + + Sbjct: 308 QQPSNYGPMKSGNFGGSRNMGGPYGGGNYG------PGGSGGSGGYGGRSR 352 Score = 55.5 bits (132), Expect = 1e-07 Identities = 51/162 (31%), Positives = 63/162 (38%), Gaps = 22/162 (13%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81 G G S+ +G S + +D GYG S +G N GYG +G + GY Sbjct: 208 GFGDSRGGGGNFGPGPGSNFRGGSD--GYG--SGRGFGDGYN-GYGGGPGGGNFGGSPGY 262 Query: 82 GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYS------QQPS 135 G + G PGYG Q G YG + G SG+Y+ QQPS Sbjct: 263 GGGRGGYGGGG-----PGYGNQ------GGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 311 Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177 G +S S N YG N SGG GG GG Y Sbjct: 312 NYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 353 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/31 (64%), Positives = 20/31 (64%), Gaps = 1/31 (3%) Query: 380 GNGRGGRGRGGPMGRGGYGGGGSGG-GGRGG 409 GN G R GGP G G YG GGSGG GG GG Sbjct: 319 GNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/30 (50%), Positives = 15/30 (50%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405 N GG GG GG G GG GG G GG Sbjct: 320 NFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349 >gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2 [Homo sapiens] Length = 341 Score = 89.7 bits (221), Expect = 6e-18 Identities = 76/240 (31%), Positives = 103/240 (42%), Gaps = 52/240 (21%) Query: 287 IFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDD-PP 345 +FV G+ E+ + DYF++ G I T I + TDR++GK +G V+FDD P Sbjct: 102 LFVGGIKEDTEEHHLRDYFEEYGKIDT--------IEIITDRQSGKKRGFGFVTFDDHDP 153 Query: 346 SAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGR-GRGGPMGRGGYGGGGS 402 K + + +G+ +V A R + + +GRGG G G G GG G G Sbjct: 154 VDKIVLQKYH--TINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGP 211 Query: 403 GG---GGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGP 459 G GG G+ SG G G G +G GGGP Sbjct: 212 GSNFRGGSDGYGSGRGFGDGY--------------------------------NGYGGGP 239 Query: 460 GGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQ 519 GG + GG+ G GGRGGY GG G G GG+ GG G +G G + G + Q Sbjct: 240 GGGNFGGSPG--YGGGRGGYGGGG-PGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQ 296 Score = 75.5 bits (184), Expect = 1e-13 Identities = 53/130 (40%), Positives = 61/130 (46%), Gaps = 21/130 (16%) Query: 157 QQNQYNSSSGGGGGG-----GGGGNYGQDQSSMSSGG----GSGGGYGNQDQSGGGGSGG 207 Q+ Q + S GG G GGGGN+G S GG GSG G+G+ GGG GG Sbjct: 182 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGG 241 Query: 208 --YGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKF 265 +G G G GG GG GGGG GY GGY GGG GG G G +N F Sbjct: 242 GNFG----GSPGYGGGRGGYGGGGPGYGNQGGGY-----GGGYDNYGG-GNYGSGNYNDF 291 Query: 266 GGPRDQGSRH 275 G Q S + Sbjct: 292 GNYNQQPSNY 301 Score = 70.5 bits (171), Expect = 4e-12 Identities = 58/173 (33%), Positives = 69/173 (39%), Gaps = 25/173 (14%) Query: 103 QPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYN 162 Q SS SG G+ +G + G + P G + G Y +G+G + YN Sbjct: 182 QEVQSSRSGRGGNFG----FGDSRGGGGNFGPGPGSNFR--GGSDGYGSGRGFG--DGYN 233 Query: 163 SSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSG 222 GG GGG GG+ G GGG G GYGNQ GGG GGY G G G Sbjct: 234 GYGGGPGGGNFGGSPGYGGGRGGYGGG-GPGYGNQ---GGGYGGGYDNY-----GGGNYG 284 Query: 223 GGGGGGGGGYNRSSGGYEPRGRG--------GGRGGRGGMGGSDRGGFNKFGG 267 G G YN+ Y P G GG G G G GG +GG Sbjct: 285 SGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337 Score = 70.1 bits (170), Expect = 5e-12 Identities = 55/161 (34%), Positives = 62/161 (38%), Gaps = 18/161 (11%) Query: 118 QSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177 QSS G+ + + GG GYG + G GGG GGGN+ Sbjct: 185 QSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNF 244 Query: 178 GQDQSSMSSGGGSGG------GYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGG 231 G S GGG GG GYGNQ GGG GGY G G G G G Sbjct: 245 G---GSPGYGGGRGGYGGGGPGYGNQ---GGGYGGGYDNY-----GGGNYGSGNYNDFGN 293 Query: 232 YNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQG 272 YN+ Y P + G GG MGG GG GG G Sbjct: 294 YNQQPSNYGPM-KSGNFGGSRNMGGPYGGGNYGPGGSGGSG 333 Score = 65.9 bits (159), Expect = 9e-11 Identities = 46/115 (40%), Positives = 54/115 (46%), Gaps = 18/115 (15%) Query: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGR 216 + + SS G GG G G+ S GG G G G+ + GGS GYG G Sbjct: 180 EMQEVQSSRSGRGGNFGFGD------SRGGGGNFGPGPGSNFR---GGSDGYGSGRGFGD 230 Query: 217 GRGGSGGGGGGG--GG--GYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGG 267 G G GGG GGG GG GY GGY GGG G G GG GG++ +GG Sbjct: 231 GYNGYGGGPGGGNFGGSPGYGGGRGGY-----GGGGPGYGNQGGGYGGGYDNYGG 280 Score = 65.9 bits (159), Expect = 9e-11 Identities = 66/200 (33%), Positives = 79/200 (39%), Gaps = 53/200 (26%) Query: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128 QS+ G G G+G S+ ++G PG P + GS G S +G +G Sbjct: 185 QSSRSGRGGNFGFGDSRGGGGNFG-----PG----PGSNFRGGSDGYGS-GRGFGDGYNG 234 Query: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188 Y P G ++G Y GGG GG GGG G + GG Sbjct: 235 -YGGGPGGG----NFGGSPGY----------------GGGRGGYGGGGPGYG----NQGG 269 Query: 189 GSGGGYGNQDQSGGG--GSGGYG-------QQDRGGRGRGGSGGGGGGGGGGYNRSSGGY 239 G GGGY D GGG GSG Y Q G + G+ GG GG Y G Y Sbjct: 270 GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPY--GGGNY 324 Query: 240 EPRGRGGGRGGRGGMGGSDR 259 P GG GG GG GG R Sbjct: 325 GP----GGSGGSGGYGGRSR 340 Score = 62.4 bits (150), Expect = 1e-09 Identities = 51/171 (29%), Positives = 65/171 (38%), Gaps = 26/171 (15%) Query: 43 QSTDTSGYGQSSYSSYGQSQNTG--YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGY 100 Q +S G+ +G S+ G +G G + GYGS + G Y GY Sbjct: 182 QEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGR------GFGDGYNGY 235 Query: 101 GQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQ----SYNPPQGYG 156 G P + GS G YG G +Q YGG +YG +YN Y Sbjct: 236 GGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYN 295 Query: 157 QQ-NQYNSSSGGGGGGG-------GGGNYGQDQSSMSSGGGSGGGYGNQDQ 199 QQ + Y G GG GGGNYG G G GGYG + + Sbjct: 296 QQPSNYGPMKSGNFGGSRNMGGPYGGGNYG------PGGSGGSGGYGGRSR 340 Score = 55.5 bits (132), Expect = 1e-07 Identities = 51/162 (31%), Positives = 63/162 (38%), Gaps = 22/162 (13%) Query: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81 G G S+ +G S + +D GYG S +G N GYG +G + GY Sbjct: 196 GFGDSRGGGGNFGPGPGSNFRGGSD--GYG--SGRGFGDGYN-GYGGGPGGGNFGGSPGY 250 Query: 82 GSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYS------QQPS 135 G + G PGYG Q G YG + G SG+Y+ QQPS Sbjct: 251 GGGRGGYGGGG-----PGYGNQ------GGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPS 299 Query: 136 YGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177 G +S S N YG N SGG GG GG Y Sbjct: 300 NYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 341 Score = 40.8 bits (94), Expect = 0.003 Identities = 20/31 (64%), Positives = 20/31 (64%), Gaps = 1/31 (3%) Query: 380 GNGRGGRGRGGPMGRGGYGGGGSGG-GGRGG 409 GN G R GGP G G YG GGSGG GG GG Sbjct: 307 GNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337 Score = 31.2 bits (69), Expect = 2.4 Identities = 15/30 (50%), Positives = 15/30 (50%) Query: 376 NRGGGNGRGGRGRGGPMGRGGYGGGGSGGG 405 N GG GG GG G GG GG G GG Sbjct: 308 NFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.135 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,911,207 Number of Sequences: 37866 Number of extensions: 2186574 Number of successful extensions: 76870 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 910 Number of HSP's successfully gapped in prelim test: 752 Number of HSP's that attempted gapping in prelim test: 12634 Number of HSP's gapped (non-prelim): 22568 length of query: 526 length of database: 18,247,518 effective HSP length: 107 effective length of query: 419 effective length of database: 14,195,856 effective search space: 5948063664 effective search space used: 5948063664 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.