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Search of human proteins with 48255918
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255918 RAR-related orphan receptor C isoform b [Homo
sapiens]
(497 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 1018 0.0
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 1013 0.0
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 458 e-129
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 457 e-128
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 456 e-128
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 456 e-128
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 437 e-122
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 220 2e-57
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso... 130 4e-30
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso... 130 4e-30
gi|116284373 peroxisome proliferative activated receptor gamma i... 116 4e-26
gi|20336229 peroxisome proliferative activated receptor gamma is... 116 4e-26
gi|116284368 peroxisome proliferative activated receptor gamma i... 116 4e-26
gi|116284370 peroxisome proliferative activated receptor gamma i... 116 4e-26
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 116 5e-26
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 115 9e-26
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 115 9e-26
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 115 9e-26
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 114 2e-25
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 113 5e-25
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 113 5e-25
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 113 5e-25
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso... 112 6e-25
gi|11415052 retinoid X receptor, beta [Homo sapiens] 111 1e-24
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom... 111 1e-24
gi|50348666 peroxisome proliferative activated receptor, alpha [... 111 2e-24
gi|7549811 peroxisome proliferative activated receptor, alpha [H... 111 2e-24
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 110 2e-24
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 109 5e-24
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 109 5e-24
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 1018 bits (2633), Expect = 0.0
Identities = 497/497 (100%), Positives = 497/497 (100%)
Query: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN
Sbjct: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
Query: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH
Sbjct: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
Query: 181 LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE 240
LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE
Sbjct: 181 LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE 240
Query: 241 APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA
Sbjct: 241 APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
Query: 301 HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK 360
HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK
Sbjct: 301 HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK 360
Query: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ
Sbjct: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
Query: 421 LQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL 480
LQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL
Sbjct: 421 LQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL 480
Query: 481 YKELFSTETESPVGLSK 497
YKELFSTETESPVGLSK
Sbjct: 481 YKELFSTETESPVGLSK 497
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 1013 bits (2619), Expect = 0.0
Identities = 494/495 (99%), Positives = 495/495 (100%)
Query: 3 TQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 62
+QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC
Sbjct: 24 SQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 83
Query: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 122
QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG
Sbjct: 84 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 143
Query: 123 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 182
ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE
Sbjct: 144 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 203
Query: 183 YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 242
YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP
Sbjct: 204 YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 263
Query: 243 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH 302
YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH
Sbjct: 264 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH 323
Query: 303 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG 362
LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG
Sbjct: 324 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG 383
Query: 363 GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 422
GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ
Sbjct: 384 GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 443
Query: 423 YNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYK 482
YNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYK
Sbjct: 444 YNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYK 503
Query: 483 ELFSTETESPVGLSK 497
ELFSTETESPVGLSK
Sbjct: 504 ELFSTETESPVGLSK 518
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 458 bits (1178), Expect = e-129
Identities = 243/492 (49%), Positives = 318/492 (64%), Gaps = 41/492 (8%)
Query: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
M+ QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRN
Sbjct: 9 MKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 68
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 69 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ---------- 118
Query: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
Q P + P P + GL + +Y +
Sbjct: 119 ---------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG------------ 151
Query: 181 LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE 240
++PE KA+ S + Q +PD+ GL + + + + SF +
Sbjct: 152 --HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGET 209
Query: 241 APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
+P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 210 SPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCA 269
Query: 301 HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK 360
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GK
Sbjct: 270 IKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGK 329
Query: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
Y ++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+
Sbjct: 330 YASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEK 389
Query: 421 LQYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFP 478
LQ ++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FP
Sbjct: 390 LQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFP 449
Query: 479 PLYKELFSTETE 490
PLYKELF++E E
Sbjct: 450 PLYKELFTSEFE 461
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 457 bits (1176), Expect = e-128
Identities = 243/492 (49%), Positives = 317/492 (64%), Gaps = 41/492 (8%)
Query: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
M QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRN
Sbjct: 97 MNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 156
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 157 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ---------- 206
Query: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
Q P + P P + GL + +Y +
Sbjct: 207 ---------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG------------ 239
Query: 181 LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE 240
++PE KA+ S + Q +PD+ GL + + + + SF +
Sbjct: 240 --HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGET 297
Query: 241 APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
+P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 298 SPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCA 357
Query: 301 HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK 360
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GK
Sbjct: 358 IKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGK 417
Query: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
Y ++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+
Sbjct: 418 YASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEK 477
Query: 421 LQYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFP 478
LQ ++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FP
Sbjct: 478 LQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFP 537
Query: 479 PLYKELFSTETE 490
PLYKELF++E E
Sbjct: 538 PLYKELFTSEFE 549
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 456 bits (1173), Expect = e-128
Identities = 242/491 (49%), Positives = 317/491 (64%), Gaps = 41/491 (8%)
Query: 2 RTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNR 61
+ QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRNR
Sbjct: 90 KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNR 149
Query: 62 CQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQ 121
CQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 150 CQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ----------- 198
Query: 122 GADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHL 181
Q P + P P + GL + +Y +
Sbjct: 199 --------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG------------- 231
Query: 182 EYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEA 241
++PE KA+ S + Q +PD+ GL + + + + SF + +
Sbjct: 232 -HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETS 290
Query: 242 PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAH 301
P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 291 PTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAI 350
Query: 302 HLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKY 361
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GKY
Sbjct: 351 KITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKY 410
Query: 362 GGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQL 421
++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+L
Sbjct: 411 ASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKL 470
Query: 422 QYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPP 479
Q ++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FPP
Sbjct: 471 QQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 530
Query: 480 LYKELFSTETE 490
LYKELF++E E
Sbjct: 531 LYKELFTSEFE 541
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 456 bits (1172), Expect = e-128
Identities = 242/490 (49%), Positives = 317/490 (64%), Gaps = 41/490 (8%)
Query: 3 TQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 62
+QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRNRC
Sbjct: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
Query: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 122
QHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ------------ 173
Query: 123 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 182
Q P + P P + GL + +Y +
Sbjct: 174 -------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG-------------- 206
Query: 183 YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 242
++PE KA+ S + Q +PD+ GL + + + + SF + +P
Sbjct: 207 HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSP 266
Query: 243 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH 302
S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 267 TVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIK 326
Query: 303 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG 362
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GKY
Sbjct: 327 ITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYA 386
Query: 363 GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 422
++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+LQ
Sbjct: 387 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 446
Query: 423 YNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL 480
++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FPPL
Sbjct: 447 QKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPL 506
Query: 481 YKELFSTETE 490
YKELF++E E
Sbjct: 507 YKELFTSEFE 516
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 437 bits (1124), Expect = e-122
Identities = 242/497 (48%), Positives = 327/497 (65%), Gaps = 53/497 (10%)
Query: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
MR QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA+YSC RQ+NC IDRT+RN
Sbjct: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
Query: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSL+AEVQK Q+ Q+Q+Q+ +G
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ------SGE 114
Query: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
A Y+ + +G L + + SG+ Y+N H
Sbjct: 115 AEALARVYSSSISNGLSNLNN---------------ETSGT---YANG-----------H 145
Query: 181 LEYSPERGKAEGRESFYSTGS-QLTPDRCGLRF---EEHRHPGLGELGQGPDSYGSPSFR 236
+ P K+EG +Y+ S Q +PD+ GL ++ + + +L P+ + SF
Sbjct: 146 VIDLP---KSEG---YYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFN 199
Query: 237 STPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMW 296
+ AP ++TEI+ + Q++ KS+ ETCQ +E+L + + EE+ YQ KS +W
Sbjct: 200 NGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALW 259
Query: 297 ERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVF 356
++CA +T AIQYVVEFAKR++GFMELCQNDQI+LLK+G +EVVLVRMCRA+N N TV
Sbjct: 260 QQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVL 319
Query: 357 FEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKR 416
FEGKYGGM++F+ALG +L++ FDF+ +L +L +E+EIAL+++ VLI+ R L E R
Sbjct: 320 FEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPR 379
Query: 417 KVEQLQYNLELAFHHHLCKTHRQ-----SILAKLPPKGKLRSLCSQHVERLQIFQHLHPI 471
KV++LQ + A H + K H ++AK+P + ++C+ H E+LQ+F+ HP
Sbjct: 380 KVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP---TITAVCNLHGEKLQVFKQSHPE 436
Query: 472 VVQAAFPPLYKELFSTE 488
+V FPPLYKELF+ +
Sbjct: 437 IVNTLFPPLYKELFNPD 453
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 220 bits (561), Expect = 2e-57
Identities = 163/499 (32%), Positives = 245/499 (49%), Gaps = 56/499 (11%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYS-CTRQQNCPIDRTSRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS + N Y C + +NC I R +RNRCQ C
Sbjct: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQK--QLQQRQQQQQEPVVKTP------- 116
R +KCL++GMSRDAV+FGR+ K+++ + AE+Q L Q Q P+ +P
Sbjct: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPG 248
Query: 117 -----PAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAK 171
P A L P P S P + +A +Y+++ K
Sbjct: 249 PMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHD--K 306
Query: 172 AGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSY- 230
G + + + ++ A + + G P+ + + L L Q P SY
Sbjct: 307 LGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYP 366
Query: 231 ---------------GSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQR 275
S R P YA+ ++ S R+ + LL
Sbjct: 367 PTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEG-----KAPANSPRQGNSKNV--LLACP 419
Query: 276 SNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAG 335
N++ G +++ E+WE + T A++ VVEFAK + GF +L Q+DQ+ LLKAG
Sbjct: 420 MNMYPH----GRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAG 475
Query: 336 AMEVVLVRMCRAYNADNRTVFFEGK--YGGMELFRALGCSELISSIFDFSHSLSALHFSE 393
EV++VR +N ++TV F + Y EL A+G +L+S++FDFS L++L +E
Sbjct: 476 TFEVLMVRFASLFNVKDQTVMFLSRTTYSLQEL-GAMGMGDLLSAMFDFSEKLNSLALTE 534
Query: 394 DEIALYTALVLINAHRPGLQEKRKVEQLQYNL-----ELAFHHHLCKTHR-QSILAKLPP 447
+E+ L+TA+VL++A R G++ VEQLQ L L + +T R +L KLP
Sbjct: 535 EELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLP- 593
Query: 448 KGKLRSLCSQHVERLQIFQ 466
LR+L + H E+L F+
Sbjct: 594 --DLRTLNNMHSEKLLSFR 610
>gi|224177493 nuclear receptor subfamily 1, group D, member 2
isoform 2 [Homo sapiens]
Length = 504
Score = 130 bits (326), Expect = 4e-30
Identities = 78/185 (42%), Positives = 114/185 (61%), Gaps = 5/185 (2%)
Query: 290 KSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYN 349
KS E+WE + T A++ VVEFAKR+ GF +L Q+DQ+ LLKAG EV++VR ++
Sbjct: 321 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD 380
Query: 350 ADNRTV-FFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAH 408
A RTV F GK ++ ++G +L++S+F+FS L+AL S++E++L+TA+VL++A
Sbjct: 381 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD 440
Query: 409 RPGLQEKRKVEQLQYNLELAFHHHLCKTH--RQSILAKLPPK-GKLRSLCSQHVERLQIF 465
R G++ VE LQ L A + K H SI KL K LRSL + H E L F
Sbjct: 441 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF 500
Query: 466 QHLHP 470
+ +HP
Sbjct: 501 K-VHP 504
Score = 122 bits (306), Expect = 8e-28
Identities = 54/103 (52%), Positives = 73/103 (70%), Gaps = 1/103 (0%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYS-CTRQQNCPIDRTSRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS + N Y C + +NC I R +RNRCQ C
Sbjct: 25 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 84
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQ 108
R +KCL++GMSRDAV+FGR+ K+++ + E+Q ++ Q
Sbjct: 85 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ 127
>gi|224177491 nuclear receptor subfamily 1, group D, member 2
isoform 1 [Homo sapiens]
Length = 579
Score = 130 bits (326), Expect = 4e-30
Identities = 78/185 (42%), Positives = 114/185 (61%), Gaps = 5/185 (2%)
Query: 290 KSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYN 349
KS E+WE + T A++ VVEFAKR+ GF +L Q+DQ+ LLKAG EV++VR ++
Sbjct: 396 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD 455
Query: 350 ADNRTV-FFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAH 408
A RTV F GK ++ ++G +L++S+F+FS L+AL S++E++L+TA+VL++A
Sbjct: 456 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD 515
Query: 409 RPGLQEKRKVEQLQYNLELAFHHHLCKTH--RQSILAKLPPK-GKLRSLCSQHVERLQIF 465
R G++ VE LQ L A + K H SI KL K LRSL + H E L F
Sbjct: 516 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF 575
Query: 466 QHLHP 470
+ +HP
Sbjct: 576 K-VHP 579
Score = 122 bits (306), Expect = 8e-28
Identities = 54/103 (52%), Positives = 73/103 (70%), Gaps = 1/103 (0%)
Query: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYS-CTRQQNCPIDRTSRNRCQHC 65
V+ CK+CGD +SG HYGV CEGCKGFFRRS + N Y C + +NC I R +RNRCQ C
Sbjct: 100 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 159
Query: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQ 108
R +KCL++GMSRDAV+FGR+ K+++ + E+Q ++ Q
Sbjct: 160 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ 202
>gi|116284373 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 116 bits (291), Expect = 4e-26
Identities = 51/96 (53%), Positives = 68/96 (70%), Gaps = 1/96 (1%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRL 67
I C++CGDK+SG HYGV CEGCKGFFRR+ R Y NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC-DLNCRIHKKSRNKCQYCRF 167
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ 103
QKCLA+GMS +A++FGRM + +++ L AE+ + Q
Sbjct: 168 QKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQ 203
Score = 89.0 bits (219), Expect = 9e-18
Identities = 56/202 (27%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 295 MWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRT 354
+++ C EA+Q + E+AK + GF+ L NDQ+ LLK G E++ + N D
Sbjct: 281 IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVL 340
Query: 355 VFFEGKYGGMELFRAL--GCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGL 412
+ + E ++L + + F+F+ +AL + ++A++ A+++++ RPGL
Sbjct: 341 ISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGL 400
Query: 413 QEKRKVEQLQYNLELAFHHHLCKTHRQS--ILAKLPPK-GKLRSLCSQHVERLQIFQ--- 466
+ +E +Q NL A L H +S + AKL K LR + ++HV+ LQ+ +
Sbjct: 401 LNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE 460
Query: 467 ---HLHPIVVQAAFPPLYKELF 485
LHP++ + +YK+L+
Sbjct: 461 TDMSLHPLLQE-----IYKDLY 477
>gi|20336229 peroxisome proliferative activated receptor gamma
isoform 2 [Homo sapiens]
Length = 505
Score = 116 bits (291), Expect = 4e-26
Identities = 51/96 (53%), Positives = 68/96 (70%), Gaps = 1/96 (1%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRL 67
I C++CGDK+SG HYGV CEGCKGFFRR+ R Y NC I + SRN+CQ+CR
Sbjct: 137 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC-DLNCRIHKKSRNKCQYCRF 195
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ 103
QKCLA+GMS +A++FGRM + +++ L AE+ + Q
Sbjct: 196 QKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQ 231
Score = 89.0 bits (219), Expect = 9e-18
Identities = 56/202 (27%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 295 MWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRT 354
+++ C EA+Q + E+AK + GF+ L NDQ+ LLK G E++ + N D
Sbjct: 309 IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVL 368
Query: 355 VFFEGKYGGMELFRAL--GCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGL 412
+ + E ++L + + F+F+ +AL + ++A++ A+++++ RPGL
Sbjct: 369 ISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGL 428
Query: 413 QEKRKVEQLQYNLELAFHHHLCKTHRQS--ILAKLPPK-GKLRSLCSQHVERLQIFQ--- 466
+ +E +Q NL A L H +S + AKL K LR + ++HV+ LQ+ +
Sbjct: 429 LNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE 488
Query: 467 ---HLHPIVVQAAFPPLYKELF 485
LHP++ + +YK+L+
Sbjct: 489 TDMSLHPLLQE-----IYKDLY 505
>gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 116 bits (291), Expect = 4e-26
Identities = 51/96 (53%), Positives = 68/96 (70%), Gaps = 1/96 (1%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRL 67
I C++CGDK+SG HYGV CEGCKGFFRR+ R Y NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC-DLNCRIHKKSRNKCQYCRF 167
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ 103
QKCLA+GMS +A++FGRM + +++ L AE+ + Q
Sbjct: 168 QKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQ 203
Score = 89.0 bits (219), Expect = 9e-18
Identities = 56/202 (27%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 295 MWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRT 354
+++ C EA+Q + E+AK + GF+ L NDQ+ LLK G E++ + N D
Sbjct: 281 IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVL 340
Query: 355 VFFEGKYGGMELFRAL--GCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGL 412
+ + E ++L + + F+F+ +AL + ++A++ A+++++ RPGL
Sbjct: 341 ISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGL 400
Query: 413 QEKRKVEQLQYNLELAFHHHLCKTHRQS--ILAKLPPK-GKLRSLCSQHVERLQIFQ--- 466
+ +E +Q NL A L H +S + AKL K LR + ++HV+ LQ+ +
Sbjct: 401 LNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE 460
Query: 467 ---HLHPIVVQAAFPPLYKELF 485
LHP++ + +YK+L+
Sbjct: 461 TDMSLHPLLQE-----IYKDLY 477
>gi|116284370 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 116 bits (291), Expect = 4e-26
Identities = 51/96 (53%), Positives = 68/96 (70%), Gaps = 1/96 (1%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRL 67
I C++CGDK+SG HYGV CEGCKGFFRR+ R Y NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC-DLNCRIHKKSRNKCQYCRF 167
Query: 68 QKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ 103
QKCLA+GMS +A++FGRM + +++ L AE+ + Q
Sbjct: 168 QKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQ 203
Score = 89.0 bits (219), Expect = 9e-18
Identities = 56/202 (27%), Positives = 104/202 (51%), Gaps = 16/202 (7%)
Query: 295 MWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRT 354
+++ C EA+Q + E+AK + GF+ L NDQ+ LLK G E++ + N D
Sbjct: 281 IFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVL 340
Query: 355 VFFEGKYGGMELFRAL--GCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGL 412
+ + E ++L + + F+F+ +AL + ++A++ A+++++ RPGL
Sbjct: 341 ISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGL 400
Query: 413 QEKRKVEQLQYNLELAFHHHLCKTHRQS--ILAKLPPK-GKLRSLCSQHVERLQIFQ--- 466
+ +E +Q NL A L H +S + AKL K LR + ++HV+ LQ+ +
Sbjct: 401 LNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTE 460
Query: 467 ---HLHPIVVQAAFPPLYKELF 485
LHP++ + +YK+L+
Sbjct: 461 TDMSLHPLLQE-----IYKDLY 477
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 116 bits (290), Expect = 5e-26
Identities = 51/86 (59%), Positives = 64/86 (74%)
Query: 4 QIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQ 63
Q + I C +CGDKSSG HYG TCEGCK FF+RS R N +Y+C +NCPID+ RN+CQ
Sbjct: 73 QQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQ 132
Query: 64 HCRLQKCLALGMSRDAVKFGRMSKKQ 89
+CRL+KCL +GM R+AV+ GRM Q
Sbjct: 133 YCRLKKCLKVGMRREAVQRGRMPPTQ 158
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 115 bits (288), Expect = 9e-26
Identities = 50/82 (60%), Positives = 61/82 (74%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRL 67
I C +CGDKSSG HYG TCEGCK FF+RS R N Y+C +NCPID+ RN+CQ+CRL
Sbjct: 84 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRL 143
Query: 68 QKCLALGMSRDAVKFGRMSKKQ 89
+KCL +GM R+AV+ GRM Q
Sbjct: 144 KKCLKVGMRREAVQRGRMPPTQ 165
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 115 bits (288), Expect = 9e-26
Identities = 49/81 (60%), Positives = 63/81 (77%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV +CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 78 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 137
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS++AV+ R KK+
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKK 158
Score = 79.3 bits (194), Expect = 7e-15
Identities = 56/188 (29%), Positives = 91/188 (48%), Gaps = 21/188 (11%)
Query: 243 YASLTEIEHLVQSVCKSYRET----CQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWER 298
Y ++E L+ V K+++ET CQL ++ ++ + +W++
Sbjct: 169 YELSPQLEELITKVSKAHQETFPSLCQL----------GKYTTNSSADHRVQLDLGLWDK 218
Query: 299 CAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFE 358
+ T+ I +VEFAKRL GF L DQI LLKA ++++++R+C Y + T+ F
Sbjct: 219 FSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFS 278
Query: 359 GKYGGMELFRA----LGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQE 414
G+ L R G L +F F+ L L + E L +A+ LI R L+E
Sbjct: 279 ---DGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEE 335
Query: 415 KRKVEQLQ 422
KV++LQ
Sbjct: 336 PEKVDKLQ 343
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 115 bits (288), Expect = 9e-26
Identities = 49/81 (60%), Positives = 63/81 (77%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV +CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 89 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 148
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS++AV+ R KK+
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKK 169
Score = 79.3 bits (194), Expect = 7e-15
Identities = 56/188 (29%), Positives = 91/188 (48%), Gaps = 21/188 (11%)
Query: 243 YASLTEIEHLVQSVCKSYRET----CQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWER 298
Y ++E L+ V K+++ET CQL ++ ++ + +W++
Sbjct: 180 YELSPQLEELITKVSKAHQETFPSLCQL----------GKYTTNSSADHRVQLDLGLWDK 229
Query: 299 CAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFE 358
+ T+ I +VEFAKRL GF L DQI LLKA ++++++R+C Y + T+ F
Sbjct: 230 FSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFS 289
Query: 359 GKYGGMELFRA----LGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQE 414
G+ L R G L +F F+ L L + E L +A+ LI R L+E
Sbjct: 290 ---DGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEE 346
Query: 415 KRKVEQLQ 422
KV++LQ
Sbjct: 347 PEKVDKLQ 354
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 114 bits (285), Expect = 2e-25
Identities = 49/84 (58%), Positives = 63/84 (75%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 80 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQ 139
Query: 69 KCLALGMSRDAVKFGRMSKKQRDS 92
KC +GMS+++V+ R KK+ S
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKETS 163
Score = 85.9 bits (211), Expect = 8e-17
Identities = 71/263 (26%), Positives = 126/263 (47%), Gaps = 29/263 (11%)
Query: 243 YASLTEIEHLVQSVCKSYRET----CQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWER 298
Y E++ L + + K+++ET CQL ++ ++ + +W++
Sbjct: 171 YEMTAELDDLTEKIRKAHQETFPSLCQL----------GKYTTNSSADHRVRLDLGLWDK 220
Query: 299 CAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFE 358
+ T+ I +VEFAKRL GF L DQI LLKA ++++++R+C Y + T+ F
Sbjct: 221 FSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFS 280
Query: 359 GKYGGMELFRA----LGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQE 414
G+ L R G L +F F++ L L + E L +A+ LI R L+E
Sbjct: 281 ---DGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEE 337
Query: 415 KRKVEQLQYNLELAFHHHLCKTH--RQSILAKLPPK-GKLRSLCSQHVERLQIFQHLHPI 471
KV++LQ L A ++ K + + K+ K LRS+ ++ ER+ + +
Sbjct: 338 PTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLK----M 393
Query: 472 VVQAAFPPLYKELF-STETESPV 493
+ + PPL +E+ ++E P+
Sbjct: 394 EIPGSMPPLIQEMLENSEGHEPL 416
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 113 bits (282), Expect = 5e-25
Identities = 48/81 (59%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 83.2 bits (204), Expect = 5e-16
Identities = 76/281 (27%), Positives = 131/281 (46%), Gaps = 35/281 (12%)
Query: 222 ELGQGPDSYGSPSFRSTPEAP-------YASLTEIEHLVQSVCKSYRET----CQLRLED 270
E+G +S + + E P Y E+ L++ V K+++ET CQL
Sbjct: 150 EVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLG--- 206
Query: 271 LLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIV 330
+ +N S + V+ ++W++ + T+ I VEFAK+L GF L DQI
Sbjct: 207 --KYTTNNSSEQRVS-----LDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQIT 259
Query: 331 LLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA----LGCSELISSIFDFSHSL 386
LLKA ++++++R+C Y + T+ F G+ L R G L +F F++ L
Sbjct: 260 LLKAACLDILILRICTRYTPEQDTMTFS---DGLTLNRTQMHNAGFGPLTDLVFAFANQL 316
Query: 387 SALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTH--RQSILAK 444
L + E L +A+ LI R L++ +V+ LQ L A ++ K R + K
Sbjct: 317 LPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPK 376
Query: 445 LPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKEL 484
+ K LRS+ ++ ER+ + + + + PPL +E+
Sbjct: 377 MLMKITDLRSISAKGAERVITLK----MEIPGSMPPLIQEM 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 113 bits (282), Expect = 5e-25
Identities = 48/81 (59%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 82 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 141
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 142 KCFEVGMSKESVRNDRNKKKK 162
Score = 83.2 bits (204), Expect = 5e-16
Identities = 76/281 (27%), Positives = 131/281 (46%), Gaps = 35/281 (12%)
Query: 222 ELGQGPDSYGSPSFRSTPEAP-------YASLTEIEHLVQSVCKSYRET----CQLRLED 270
E+G +S + + E P Y E+ L++ V K+++ET CQL
Sbjct: 145 EVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLG--- 201
Query: 271 LLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIV 330
+ +N S + V+ ++W++ + T+ I VEFAK+L GF L DQI
Sbjct: 202 --KYTTNNSSEQRVS-----LDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQIT 254
Query: 331 LLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA----LGCSELISSIFDFSHSL 386
LLKA ++++++R+C Y + T+ F G+ L R G L +F F++ L
Sbjct: 255 LLKAACLDILILRICTRYTPEQDTMTFS---DGLTLNRTQMHNAGFGPLTDLVFAFANQL 311
Query: 387 SALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTH--RQSILAK 444
L + E L +A+ LI R L++ +V+ LQ L A ++ K R + K
Sbjct: 312 LPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPK 371
Query: 445 LPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKEL 484
+ K LRS+ ++ ER+ + + + + PPL +E+
Sbjct: 372 MLMKITDLRSISAKGAERVITLK----MEIPGSMPPLIQEM 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 113 bits (282), Expect = 5e-25
Identities = 48/81 (59%), Positives = 62/81 (76%)
Query: 9 PCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQ 68
PC +C DKSSG HYGV CEGCKGFFRRS + N Y+C R +NC I++ +RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 69 KCLALGMSRDAVKFGRMSKKQ 89
KC +GMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 83.2 bits (204), Expect = 5e-16
Identities = 76/281 (27%), Positives = 131/281 (46%), Gaps = 35/281 (12%)
Query: 222 ELGQGPDSYGSPSFRSTPEAP-------YASLTEIEHLVQSVCKSYRET----CQLRLED 270
E+G +S + + E P Y E+ L++ V K+++ET CQL
Sbjct: 150 EVGMSKESVRNDRNKKKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLG--- 206
Query: 271 LLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIV 330
+ +N S + V+ ++W++ + T+ I VEFAK+L GF L DQI
Sbjct: 207 --KYTTNNSSEQRVS-----LDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQIT 259
Query: 331 LLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA----LGCSELISSIFDFSHSL 386
LLKA ++++++R+C Y + T+ F G+ L R G L +F F++ L
Sbjct: 260 LLKAACLDILILRICTRYTPEQDTMTFS---DGLTLNRTQMHNAGFGPLTDLVFAFANQL 316
Query: 387 SALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTH--RQSILAK 444
L + E L +A+ LI R L++ +V+ LQ L A ++ K R + K
Sbjct: 317 LPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPK 376
Query: 445 LPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKEL 484
+ K LRS+ ++ ER+ + + + + PPL +E+
Sbjct: 377 MLMKITDLRSISAKGAERVITLK----MEIPGSMPPLIQEM 413
>gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
Length = 603
Score = 112 bits (281), Expect = 6e-25
Identities = 109/450 (24%), Positives = 195/450 (43%), Gaps = 44/450 (9%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C +CGDK+SG HYG +TCEGCKGFF+RS R N YSC ++C I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 70 CLALGMSRDAVKFGR----MSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADT 125
C+A GM +D+V+ R +S+++ + A +K ++ + P+ TP
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRK--DLRSPLTATPTFVTDSES- 229
Query: 126 LTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAK-AGLNGASCHLEYS 184
T + GL D + + P + + +L S S +L+ A + + +L +
Sbjct: 230 -TRSTGLLDSGMFMNIHPSGVKTES---AVLMTSDKAESCQGDLSTLANVVTSLANLGKT 285
Query: 185 PERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYG---SPSFRSTPEA 241
+ + S + S C F+E + G++ + D+ +P + ++
Sbjct: 286 KDLSQNSNEMSMIESLSNDDTSLC--EFQEMQTN--GDVSRAFDTLAKALNPGESTACQS 341
Query: 242 PYASLTEIEHLVQSVCK-SYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
A + HL+ +Y E E L S++ R + + +
Sbjct: 342 SVAGMEGSVHLITGDSSINYTEK-----EGPLLSDSHVAFRLTMPSPMPEYL------NV 390
Query: 301 HHLTEAIQYV----VEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVF 356
H++ E+ + + +A + F L Q + I L+KA E+ + + + + N
Sbjct: 391 HYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATI 450
Query: 357 FEG---------KYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINA 407
+ M R E I + +F +S+ L E A A+VL +
Sbjct: 451 LATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSP 510
Query: 408 HRPGLQEKRKVEQLQYNLELAFHHHLCKTH 437
P L+ ++E+ Q + F ++ KT+
Sbjct: 511 DHPSLENMEQIEKFQEKAYVEFQDYITKTY 540
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 111 bits (278), Expect = 1e-24
Identities = 59/146 (40%), Positives = 80/146 (54%), Gaps = 14/146 (9%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C ICGD+SSG HYGV +CEGCKGFF+R+ R + YSC ++C +D+ RNRCQ+CR QK
Sbjct: 205 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQK 264
Query: 70 CLALGMSRDAVKFGRMSKKQRD----SLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADT 125
CLA GM R+AV+ R K +D ++ R + + V + G +G
Sbjct: 265 CLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEG--- 321
Query: 126 LTYTLGLPDGQLPLGSSPDLPEASAC 151
P G GSSP+ P + C
Sbjct: 322 -------PGGTGGSGSSPNDPVTNIC 340
Score = 40.8 bits (94), Expect = 0.003
Identities = 36/161 (22%), Positives = 70/161 (43%), Gaps = 14/161 (8%)
Query: 310 VVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA 369
+VE+AKR+ F L +DQ++LL+AG E+++ + D R G+ + R
Sbjct: 350 LVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHR-SIDVRDGILLAT--GLHVHRN 406
Query: 370 LGCSELISSIFD-----FSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYN 424
S + +IFD + + + E+ A++L N GL +VE L+
Sbjct: 407 SAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREK 466
Query: 425 LELAFHHHLCKTHRQ------SILAKLPPKGKLRSLCSQHV 459
+ + + + + + +L +LP + C +H+
Sbjct: 467 VYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHL 507
>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
sapiens]
Length = 615
Score = 111 bits (278), Expect = 1e-24
Identities = 123/488 (25%), Positives = 205/488 (42%), Gaps = 38/488 (7%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C +CGDK+SG HYG ++CEGCKGFF+RS R N YSC Q+C I++ RNRCQ CRL+K
Sbjct: 136 CVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKK 195
Query: 70 CLALGMSRDAVKFGRMS---KKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTL 126
CL +GM ++V+ R ++++ S A +++ R + + P++ TP A D
Sbjct: 196 CLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIR-KDLRSPLIATPTFVAD-KDGA 253
Query: 127 TYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNL--AKAGLNGASCHLEYS 184
T L G L P + E +L A+ S S A + + +L S
Sbjct: 254 RQTGLLDPGMLVNIQQPLIREDGT----VLLATDSKAETSQGALGTLANVVTSLANLSES 309
Query: 185 PERGKAEGRESFYSTGSQLTP--DRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 242
G + + S++T D L G D+ G S
Sbjct: 310 LNNGDTSEIQPEDQSASEITRAFDTLAKALNTTDSSSSPSLADGIDTSGGGSIHVISRDQ 369
Query: 243 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNI-FSREEVTGYQRKSMWEMWERCAH 301
+ E+E + S T +L + + + N+ + E + SM W R
Sbjct: 370 STPIIEVEGPLLS---DTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSM--HWARS-- 422
Query: 302 HLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADN-RTVFFEGK 360
A Q + + + + C N+ L A +V+ + A ++ + E K
Sbjct: 423 --IPAFQALGQDCN--TSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDK 478
Query: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
G + + + E I + +F +S++ L E A A+VL + PGL ++E+
Sbjct: 479 LSGDRIKQVM---EHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEK 535
Query: 421 LQYNLELAFHHHLCKTHRQS------ILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQ 474
Q ++ ++ KT+ + IL +LP LR + S E L + + +
Sbjct: 536 FQEKAQMELQDYVQKTYSEDTYRLARILVRLP---ALRLMSSNITEELFFTGLIGNVSID 592
Query: 475 AAFPPLYK 482
+ P + K
Sbjct: 593 SIIPYILK 600
>gi|50348666 peroxisome proliferative activated receptor, alpha
[Homo sapiens]
Length = 468
Score = 111 bits (277), Expect = 2e-24
Identities = 49/91 (53%), Positives = 66/91 (72%), Gaps = 3/91 (3%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAY-SCTRQQNCPIDRTSRNRCQHCR 66
I C+ICGDK+SG HYGV CEGCKGFFRR+ R Y C R +C I + +RN+CQ+CR
Sbjct: 100 IECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDR--SCKIQKKNRNKCQYCR 157
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLHAEV 97
KCL++GMS +A++FGRM + ++ L AE+
Sbjct: 158 FHKCLSVGMSHNAIRFGRMPRSEKAKLKAEI 188
Score = 80.9 bits (198), Expect = 3e-15
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 9/224 (4%)
Query: 268 LEDLLRQRSNIFSREEVTGYQRKSMW-EMWERCAHHLTEAIQYVVEFAKRLSGFMELCQN 326
+E L + ++ G Q K ++ C E + + EFAK + GF L N
Sbjct: 244 METLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLN 303
Query: 327 DQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALG--CSELISSIFDFSH 384
DQ+ LLK G E + + N D V + + E ++L +++ FDF+
Sbjct: 304 DQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAM 363
Query: 385 SLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILA- 443
+AL + +I+L+ A ++ RPGL +E++Q + HL H I
Sbjct: 364 KFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLF 423
Query: 444 --KLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELF 485
L LR L ++H + +QI + AA PL +E++
Sbjct: 424 PKLLQKMADLRQLVTEHAQLVQIIKKTES---DAALHPLLQEIY 464
>gi|7549811 peroxisome proliferative activated receptor, alpha [Homo
sapiens]
Length = 468
Score = 111 bits (277), Expect = 2e-24
Identities = 49/91 (53%), Positives = 66/91 (72%), Gaps = 3/91 (3%)
Query: 8 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAY-SCTRQQNCPIDRTSRNRCQHCR 66
I C+ICGDK+SG HYGV CEGCKGFFRR+ R Y C R +C I + +RN+CQ+CR
Sbjct: 100 IECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDR--SCKIQKKNRNKCQYCR 157
Query: 67 LQKCLALGMSRDAVKFGRMSKKQRDSLHAEV 97
KCL++GMS +A++FGRM + ++ L AE+
Sbjct: 158 FHKCLSVGMSHNAIRFGRMPRSEKAKLKAEI 188
Score = 80.9 bits (198), Expect = 3e-15
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 9/224 (4%)
Query: 268 LEDLLRQRSNIFSREEVTGYQRKSMW-EMWERCAHHLTEAIQYVVEFAKRLSGFMELCQN 326
+E L + ++ G Q K ++ C E + + EFAK + GF L N
Sbjct: 244 METLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLN 303
Query: 327 DQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALG--CSELISSIFDFSH 384
DQ+ LLK G E + + N D V + + E ++L +++ FDF+
Sbjct: 304 DQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAM 363
Query: 385 SLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILA- 443
+AL + +I+L+ A ++ RPGL +E++Q + HL H I
Sbjct: 364 KFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLF 423
Query: 444 --KLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELF 485
L LR L ++H + +QI + AA PL +E++
Sbjct: 424 PKLLQKMADLRQLVTEHAQLVQIIKKTES---DAALHPLLQEIY 464
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 110 bits (276), Expect = 2e-24
Identities = 59/143 (41%), Positives = 83/143 (58%), Gaps = 9/143 (6%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C ICGD+SSG HYGV +CEGCKGFF+R+ R + Y+C ++C ID+ RNRCQ+CR QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADT-LTY 128
CLA+GM R+AV+ R K R+ EV+ + E +++ A +T +
Sbjct: 195 CLAMGMKREAVQEERQRGKDRN--ENEVESTSSANEDMPVERILEAELAVEPKTETYVEA 252
Query: 129 TLGLPDGQLPLGSSPDLPEASAC 151
+GL SSP+ P + C
Sbjct: 253 NMGLNP------SSPNDPVTNIC 269
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 18/163 (11%)
Query: 310 VVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRA 369
+VE+AKR+ F EL +DQ++LL+AG E+++ A + G+ + R
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLA---TGLHVHRN 335
Query: 370 LGCSELISSIFD-----FSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYN 424
S + +IFD + + + E+ A+VL N GL +VE L+
Sbjct: 336 SAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREK 395
Query: 425 LELAFHHHLCKTHR--------QSILAKLPPKGKLRSLCSQHV 459
+ + + CK H+ +L +LP + C +H+
Sbjct: 396 VYASLEAY-CK-HKYPEQPGRFAKLLLRLPALRSIGLKCLEHL 436
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 109 bits (273), Expect = 5e-24
Identities = 50/108 (46%), Positives = 71/108 (65%), Gaps = 4/108 (3%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C +CGD ++ HYGV TCEGCKGFF+R+ + NA Y C +NCP+D+ RNRCQ+CR QK
Sbjct: 303 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 362
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPP 117
CL++GM ++ V+ + K +R L ++ + LQQ Q P +PP
Sbjct: 363 CLSVGMVKEVVRTDSL-KGRRGRLPSKPKSPLQQEPSQPSPP---SPP 406
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/167 (27%), Positives = 88/167 (52%), Gaps = 13/167 (7%)
Query: 303 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRM-CRAYNADNRTVFFEG-K 360
LT +I +A+++ GF +L + DQ +L+++ +E+ ++R+ R+ A+++ VF G
Sbjct: 452 LTASIDVSRSWAEKIPGFTDLPKEDQTLLIESAFLELFVLRLSIRSNTAEDKFVFCNGLV 511
Query: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
++ R G E + SI DFS +L +L+ +A +AL +I R GL+E ++VE+
Sbjct: 512 LHRLQCLRGFG--EWLDSIKDFSLNLQSLNLDIQALACLSALSMI-TERHGLKEPKRVEE 568
Query: 421 LQYNLELAFHHHLCKTH-----RQSILAKLPPKGKLRSLCSQHVERL 462
L + + H K +L L +LR +C+ ++R+
Sbjct: 569 LCNKITSSLKDHQSKGQALEPTESKVLGALV---ELRKICTLGLQRI 612
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 109 bits (273), Expect = 5e-24
Identities = 50/108 (46%), Positives = 71/108 (65%), Gaps = 4/108 (3%)
Query: 10 CKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQK 69
C +CGD ++ HYGV TCEGCKGFF+R+ + NA Y C +NCP+D+ RNRCQ+CR QK
Sbjct: 292 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQK 351
Query: 70 CLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPP 117
CL++GM ++ V+ + K +R L ++ + LQQ Q P +PP
Sbjct: 352 CLSVGMVKEVVRTDSL-KGRRGRLPSKPKSPLQQEPSQPSPP---SPP 395
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,048,411
Number of Sequences: 37866
Number of extensions: 1030467
Number of successful extensions: 5967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 4891
Number of HSP's gapped (non-prelim): 811
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.