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Search of human proteins with 48255913
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255913 tripartite motif-containing 16 [Homo sapiens]
(564 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255913 tripartite motif-containing 16 [Homo sapiens] 1156 0.0
gi|82617564 tripartite motif-containing 16-like [Homo sapiens] 697 0.0
gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ... 371 e-102
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 173 3e-43
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 155 9e-38
gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] 145 1e-34
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 122 7e-28
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 119 6e-27
gi|5730009 ret finger protein [Homo sapiens] 112 1e-24
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 99 1e-20
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 92 1e-18
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 91 2e-18
gi|15208660 tripartite motif protein 21 [Homo sapiens] 89 1e-17
gi|38679905 tripartite motif-containing 65 [Homo sapiens] 87 5e-17
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 86 7e-17
gi|148833499 midline 1 [Homo sapiens] 86 9e-17
gi|4557753 midline 1 [Homo sapiens] 86 9e-17
gi|15451852 midline 1 [Homo sapiens] 86 9e-17
gi|223890259 midline 2 isoform 2 [Homo sapiens] 84 3e-16
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 77 4e-14
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 76 9e-14
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur... 76 9e-14
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 75 1e-13
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo... 75 2e-13
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ... 75 2e-13
gi|4557743 Mediterranean fever protein [Homo sapiens] 75 2e-13
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 74 3e-13
>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
Length = 564
Score = 1156 bits (2991), Expect = 0.0
Identities = 564/564 (100%), Positives = 564/564 (100%)
Query: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60
MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS
Sbjct: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60
Query: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120
DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT
Sbjct: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120
Query: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ 180
EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ
Sbjct: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ 180
Query: 181 LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK 240
LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK
Sbjct: 181 LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK 240
Query: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY 300
EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY
Sbjct: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY 300
Query: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360
VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP
Sbjct: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360
Query: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420
EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS
Sbjct: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420
Query: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY 480
QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY
Sbjct: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY 480
Query: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE 540
SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE
Sbjct: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE 540
Query: 541 NAIRIVDLGEEPEKPAPSLVGTAP 564
NAIRIVDLGEEPEKPAPSLVGTAP
Sbjct: 541 NAIRIVDLGEEPEKPAPSLVGTAP 564
>gi|82617564 tripartite motif-containing 16-like [Homo sapiens]
Length = 348
Score = 697 bits (1800), Expect = 0.0
Identities = 339/348 (97%), Positives = 345/348 (99%)
Query: 217 MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAIS 276
MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELE MAAIS
Sbjct: 1 MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELETMAAIS 60
Query: 277 NTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 336
NTVQFLEEYCKFKNTEDITFPSVY+GLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS
Sbjct: 61 NTVQFLEEYCKFKNTEDITFPSVYIGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 120
Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396
KEEEYDIRTQVSA+VQRKYWTSKPEPSTREQFLQY +DITFDPDTAHKYLRLQEENRKVT
Sbjct: 121 KEEEYDIRTQVSAIVQRKYWTSKPEPSTREQFLQYVHDITFDPDTAHKYLRLQEENRKVT 180
Query: 397 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEER 456
NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGID+KGEER
Sbjct: 181 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDQKGEER 240
Query: 457 NSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTM 516
+SCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPF RLGVYIDFPGGILSFYGVEYD+M
Sbjct: 241 SSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGGILSFYGVEYDSM 300
Query: 517 TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP 564
TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP
Sbjct: 301 TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP 348
>gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo
sapiens]
Length = 282
Score = 371 bits (952), Expect = e-102
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60
MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS
Sbjct: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60
Query: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120
DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT
Sbjct: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120
Query: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE 173
EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE
Sbjct: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE 173
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 173 bits (439), Expect = 3e-43
Identities = 147/543 (27%), Positives = 238/543 (43%), Gaps = 73/543 (13%)
Query: 9 PGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDP 68
PGP P +P AP SA P E + A + P
Sbjct: 89 PGPAPALAPEPSAP-------------SALP--------------SVPEPSAPCAPEPWP 121
Query: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNW 128
AGE + V CD C + + A SCL+C+ ++C HL PH+ + L+ H L P++
Sbjct: 122 AGE-EPVRCDACPEGAA-LPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEE 179
Query: 129 RYCPAHHSPLSAFCCPDQQCICQDC-CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKL 187
CP H PL +C ++ C+C+ C QEH GH +V L+ R +EAE + L
Sbjct: 180 SLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAE-------QSKVL 232
Query: 188 KLNENAISRLQAN--QKSVLVSVSEVKAVAEMQ-----FGELLAAVRKAQANVMLFLEEK 240
E+ + L A Q V++ + AVAE + F + AA++ Q V+ F+EE
Sbjct: 233 SAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEG 292
Query: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK-NTEDITFPS- 298
E A L ++ G E + + + +++Q L ++ +++V FL+E + ED P
Sbjct: 293 EAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSVSFLQELLALRLALEDGCGPGP 351
Query: 299 ------VYVGLKDKLSGIRKVITESTVHLIQLL------ENYKKKLQEFSKEEEYDIRTQ 346
+ + +R ++ + V+ + L E+ +KL + E D+ +
Sbjct: 352 GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLEST 411
Query: 347 VSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYP 406
+ R+ FL++AY + D DTA K+L+L K YP
Sbjct: 412 ----------NLLESEAPRDYFLKFAYIVDLDSDTADKFLQL--FGTKGVKRVLCPINYP 459
Query: 407 DLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFS 466
P+RF H QVL + +L YY+EVEI +G+ + + + N S
Sbjct: 460 LSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHS 519
Query: 467 WSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKF 526
LQWNG+ F+ W+ +E PL +GV +++ L+FY V M+L+ + K
Sbjct: 520 CCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRL--KA 577
Query: 527 SEP 529
S P
Sbjct: 578 SRP 580
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 155 bits (392), Expect = 9e-38
Identities = 131/522 (25%), Positives = 225/522 (43%), Gaps = 67/522 (12%)
Query: 74 EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133
+V CD CL + AVK+CL CM ++C+EHLQPH + Q H L PV+D R C
Sbjct: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159
Query: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENA 193
H+ FC +CIC C EH + SL A D EA L+ + ++ A
Sbjct: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRA 219
Query: 194 ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKA 253
+ ++ Q+ V ++ + + ++ E+ A + ++ ++E+E+ S+ + I
Sbjct: 220 LDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQ 279
Query: 254 HLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK--NTEDITFPSVY----------- 300
L + +E++ K+E+E+ + +FLE+ K + +T+ + P V
Sbjct: 280 ILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQ 339
Query: 301 --VGLKDKLSGIRKVITEST--------------------VHLIQLLENYKKK------- 331
+ LK++L + E T V + E KK
Sbjct: 340 STIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPAL 399
Query: 332 ---LQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST-------------REQFLQYAYDI 375
L F E+ Q K +S P ++ R + L+Y +
Sbjct: 400 PSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKV 459
Query: 376 TFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI 435
D +TAH + L E V + Y P RF + QVL +Y+EVE+
Sbjct: 460 ILDYNTAHNKVALSE-CYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518
Query: 436 FGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRR 494
VG+ ++R+G E S + N+ SW ++W + +AW++++E L + R
Sbjct: 519 QKNNFCGVGICYGSMNRQGPE--SRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATR 576
Query: 495 LGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536
+GV ++ G + F+ V D + L++KF F+E +Y AFW+
Sbjct: 577 VGVLLNCDHGFVIFFAVA-DKVHLMYKFRVDFTEALYPAFWV 617
>gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]
Length = 588
Score = 145 bits (366), Expect = 1e-34
Identities = 76/214 (35%), Positives = 120/214 (56%), Gaps = 3/214 (1%)
Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCP 132
+EVLCD C+ + + KAVKSCL C ++CE HL+PH + H L EP++D R CP
Sbjct: 169 EEVLCDSCIGNKQ--KAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCP 226
Query: 133 AHHSPLSAFCCPDQQCICQDCC-QEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNE 191
H + FC DQ CIC C QEH H+ V+++ A+ +KE EL + L+ K+ E
Sbjct: 227 VHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIE 286
Query: 192 NAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGI 251
+ + Q + + + KA+ E F +L+ + K + V LE++EQ A+ Q I
Sbjct: 287 DEAEKWQKEKDRIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVI 346
Query: 252 KAHLEYRSAEMEKSKQELERMAAISNTVQFLEEY 285
L+ R+ + + KQ E++ +IS++V FL+E+
Sbjct: 347 MDALDERAKVLHEDKQTREQLHSISDSVLFLQEF 380
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 122 bits (307), Expect = 7e-28
Identities = 126/464 (27%), Positives = 214/464 (46%), Gaps = 54/464 (11%)
Query: 93 CLTCMVNYCEEHLQPHQ-----VNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQ 147
C C L+P++ V I Q + ++D + CP HH LS FC DQ+
Sbjct: 66 CPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDES--LCPQHHEALSLFCYEDQE 123
Query: 148 CICQDCCQEHS--GHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVL 205
+C C H+ HT+V LD A ++ + +LQ LE+KL+ I+R +++++
Sbjct: 124 AVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQ----EITRCKSSEEK-- 177
Query: 206 VSVSEVKAVAEM-------QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYR 258
E+K + E +F EL + + Q ++ LEE+EQ L + AHL +
Sbjct: 178 -KPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDK 236
Query: 259 SAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITEST 318
++ E+E S E K+T + P + G LS I ++
Sbjct: 237 RRDLAHLAAEVEGKCLQSG----FEMLKDVKSTLEKNIPRKFGG---SLSTICPRDHKAL 289
Query: 319 VHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEP--STREQFLQYAYDIT 376
+ L+ K++ K + ++ T VS +++ + ++ P + R+ Q D+T
Sbjct: 290 LGLV-------KEINRCEKVKTMEV-TSVSIELEKNF-SNFPRQYFALRKILKQLIADVT 340
Query: 377 FDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIF 436
DP+TAH L L E+ + V PD P RF + VL+ + R+Y+EVE+
Sbjct: 341 LDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEV- 399
Query: 437 GAGTY--VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPL--KAGP 491
G T+ VG+ + RKGE +G W ++ WNG ++ A + TPL K P
Sbjct: 400 GDKTHWAVGVCRDSVSRKGELTPLPETG---YWRVRLWNGDKYAATTTPF-TPLHIKVKP 455
Query: 492 FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFW 535
+R+G+++D+ G LSFY V + ++ F F+E ++ F+
Sbjct: 456 -KRVGIFLDYEAGTLSFYNV--TDRSHIYTFTDTFTEKLWPLFY 496
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 119 bits (299), Expect = 6e-27
Identities = 123/462 (26%), Positives = 202/462 (43%), Gaps = 80/462 (17%)
Query: 93 CLTCMVNYCEEHLQPHQ-----VNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQ 147
C C L+P++ V I Q + ++D + CP HH LS FC DQ+
Sbjct: 66 CPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDES--LCPQHHEALSLFCYEDQE 123
Query: 148 CICQDCCQEHS--GHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVL 205
+C C H+ HT+V LD A ++ + +LQ LE+KL+ I+R +++++
Sbjct: 124 AVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQ----EITRCKSSEEK-- 177
Query: 206 VSVSEVKAVAEM-------QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYR 258
E+K + E +F EL + + Q ++ LEE+EQ L + AHL +
Sbjct: 178 -KPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDK 236
Query: 259 SAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITEST 318
+++L +AA E S + LKD S + K T
Sbjct: 237 -------RRDLAHLAA---------------EVEGKCLQSGFEMLKDVKSTLEKCEKVKT 274
Query: 319 VHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFD 378
+ + + +K F R+Y+ + R+ Q D+T D
Sbjct: 275 MEVTSVSIELEKNFSNFP----------------RQYF------ALRKILKQLIADVTLD 312
Query: 379 PDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGA 438
P+TAH L L E+ + V PD P RF + VL+ + R+Y+EVE+ G
Sbjct: 313 PETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEV-GD 371
Query: 439 GTY--VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPL--KAGPFR 493
T+ VG+ + RKGE +G W ++ WNG ++ A + TPL K P +
Sbjct: 372 KTHWAVGVCRDSVSRKGELTPLPETG---YWRVRLWNGDKYAATTTPF-TPLHIKVKP-K 426
Query: 494 RLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFW 535
R+G+++D+ G LSFY V + ++ F F+E ++ F+
Sbjct: 427 RVGIFLDYEAGTLSFYNV--TDRSHIYTFTDTFTEKLWPLFY 466
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 112 bits (279), Expect = 1e-24
Identities = 121/478 (25%), Positives = 213/478 (44%), Gaps = 63/478 (13%)
Query: 92 SCLTCMVNYCEEHLQP--HQVNI-KLQSHLLTEPVKDHNWRY--CPAHHSPLSAFCCPDQ 146
SC C + + H++P H N+ +L L TE C H PL +C DQ
Sbjct: 52 SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQ 111
Query: 147 QCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQ-KS 203
IC C +EH GH+++ L+ A + ++Q QLD +++K + R Q Q ++
Sbjct: 112 MPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQ-NQLDHLKRVK-DLKKRRRAQGEQARA 169
Query: 204 VLVSVSEVKAVAEM-QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIK-------AHL 255
L+S+++++ + +F +L ++++ + ++ LEE + A + NG +HL
Sbjct: 170 ELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHL 229
Query: 256 EYRSAEMEKSKQELER--MAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKV 313
A++E+ +Q+ R + I +T+ E I P ++ D I +
Sbjct: 230 SSLIAQLEEKQQQPTRELLQDIGDTLS---------RAERIRIPEPWITPPDLQEKIH-I 279
Query: 314 ITESTVHLIQLLENYKKKLQ-EFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYA 372
+ + L + L+ + +K+Q + K +E RE L Y+
Sbjct: 280 FAQKCLFLTESLKQFTEKMQSDMEKIQEL-----------------------REAQL-YS 315
Query: 373 YDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFE 432
D+T DPDTA+ L L + R+V + + PD P RF + VL R+Y+E
Sbjct: 316 VDVTLDPDTAYPSLILSDNLRQVRYSY-LQQDLPDNPERFNLFPCVLGSPCFIAGRHYWE 374
Query: 433 VEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPLKAG 490
VE+ + +G+ + RKG ++ +G W++ W GKE+ A S M
Sbjct: 375 VEVGDKAKWTIGVCEDSVCRKGGVTSAPQNG---FWAVSLWYGKEYWALTSPMTALPLRT 431
Query: 491 PFRRLGVYIDFPGGILSFYGV--EYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIV 546
P +R+G+++D+ G +SFY V T T H C P ++ + K A I+
Sbjct: 432 PLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLII 489
>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 101 bits (252), Expect = 2e-21
Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%)
Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175
+E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++
Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72
Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229
+C QL ++++ ++ E+A +L+AN +S K + +F EL + +
Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125
Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279
+A F+++ Q L QA+ + L+ R + + ++R+ A + T
Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185
Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336
Q +++ P + +K G+ + + EST+ I+L E+ +L + S
Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243
Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396
T+ +++ + P P R L+YA T DPDT H LRL + V
Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290
Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453
P P L RF QVL++ R+Y+EV++ GAG +VG + R+G
Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348
Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512
+ + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V
Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408
Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536
M+ +H F F EP+Y A L
Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431
>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 101 bits (252), Expect = 2e-21
Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%)
Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175
+E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++
Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72
Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229
+C QL ++++ ++ E+A +L+AN +S K + +F EL + +
Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125
Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279
+A F+++ Q L QA+ + L+ R + + ++R+ A + T
Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185
Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336
Q +++ P + +K G+ + + EST+ I+L E+ +L + S
Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243
Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396
T+ +++ + P P R L+YA T DPDT H LRL + V
Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290
Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453
P P L RF QVL++ R+Y+EV++ GAG +VG + R+G
Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348
Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512
+ + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V
Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408
Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536
M+ +H F F EP+Y A L
Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431
>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
Length = 442
Score = 101 bits (252), Expect = 2e-21
Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%)
Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175
+E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++
Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72
Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229
+C QL ++++ ++ E+A +L+AN +S K + +F EL + +
Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125
Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279
+A F+++ Q L QA+ + L+ R + + ++R+ A + T
Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185
Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336
Q +++ P + +K G+ + + EST+ I+L E+ +L + S
Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243
Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396
T+ +++ + P P R L+YA T DPDT H LRL + V
Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290
Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453
P P L RF QVL++ R+Y+EV++ GAG +VG + R+G
Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348
Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512
+ + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V
Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408
Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536
M+ +H F F EP+Y A L
Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 99.0 bits (245), Expect = 1e-20
Identities = 110/445 (24%), Positives = 188/445 (42%), Gaps = 73/445 (16%)
Query: 78 DFCLDDTRRV----KAVKSCLTCMVNYCEEHLQPHQVNIKL-QSHLLTEPVKDHNWRYCP 132
+FC + RR + +C C + +L+P++ K+ + P CP
Sbjct: 34 NFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCP 93
Query: 133 AHHSPLSAFCCPDQQCICQDCCQ--EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLN 190
AH PL+AFC + + +C C + EH H + L A D +A+L+ + L ++++
Sbjct: 94 AHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQ-- 151
Query: 191 ENAISRLQANQKSVLVS--VSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248
+ + + QA++ VL V + +F L + + + ++ LEE+E L +
Sbjct: 152 DALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRL 211
Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLS 308
AHL +SA + + ELE +
Sbjct: 212 REGAAHLGQQSAHLAELIAELEGRCQLP-------------------------------- 239
Query: 309 GIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQF 368
+ LL++ K L+ D++ Q VV + T P E
Sbjct: 240 ------------ALGLLQDIKDALRRVQ-----DVKLQPPEVVPMELRTVCRVPGLVETL 282
Query: 369 LQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHR 428
++ D+T DPDTA+ L L E+ R V PD P RF VL Q+ R
Sbjct: 283 RRFRGDVTLDPDTANPELILSEDRRSV-QRGDLRQALPDSPERFDPGPCVLGQERFTSGR 341
Query: 429 YYFEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDME--- 484
+Y+EVE+ ++ +G+ + ++RK E+ +GN F W L + G ++Y+ E
Sbjct: 342 HYWEVEVGDRTSWALGVCRENVNRK--EKGELSAGNGF-WILVFLG----SYYNSSERAL 394
Query: 485 TPLKAGPFRRLGVYIDFPGGILSFY 509
PL+ P RR+G+++D+ G LSFY
Sbjct: 395 APLRDPP-RRVGIFLDYEAGHLSFY 418
>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
Length = 630
Score = 92.0 bits (227), Expect = 1e-18
Identities = 113/453 (24%), Positives = 173/453 (38%), Gaps = 89/453 (19%)
Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQC------TQLD 182
CP H L FC D++ IC C + H H++V L+ ++ +A+LQ L+
Sbjct: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286
Query: 183 LERKLKLNENA-ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKE 241
+K+K E ++ L++ KS L +V+ +FG L + + QA + L E
Sbjct: 287 AVQKMKAKEERRVTELKSQMKSELAAVAS-------EFGRLTRFLAEEQAGLERRLREMH 339
Query: 242 QAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYV 301
+A L +A + L ++A++ + E + + + F E++ V
Sbjct: 340 EAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEV 399
Query: 302 GLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPE 361
D + +D T A+V++
Sbjct: 400 WSPDPC-----------------------------QPHSHDFLTD--AIVRKM------- 421
Query: 362 PSTREQFLQYA-YDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420
F Q A D+T DPDTAH L L + R V D P RF VL
Sbjct: 422 ---SRMFCQAARVDLTLDPDTAHPALMLSPDRRGV-RLAERRQEVADHPKRFSADCCVLG 477
Query: 421 QQSLYLHRYYFEVEIFGA-GTYVGLTCKGIDRK---GEERNSCISGNNFS---------- 466
Q R+Y+EVE+ G G VG + K G +S SG+ S
Sbjct: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537
Query: 467 ------------WSLQWNGKEFTAWYSDMETPLKAGPF-RRLGVYIDFPGGILSFYGVEY 513
W + NGK + A S +T L RR GVY+D+ G L FY E
Sbjct: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE- 596
Query: 514 DTMTLVHKFACKF-SEPVYAAFWLSKKENAIRI 545
T+ VH F+ F E V+ F + K I++
Sbjct: 597 -TLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 91.3 bits (225), Expect = 2e-18
Identities = 123/477 (25%), Positives = 184/477 (38%), Gaps = 87/477 (18%)
Query: 68 PAGEG--KEVLCDFCLDDTRRVKAVKS----CLTCMVNYCEEH----------------L 105
P GE ++ C CLD + +V CL C+ +CE+
Sbjct: 5 PPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPF 64
Query: 106 QPHQVNIKLQSHLLTEPVK------DHNWRYCPAHHSPLSAFCCPDQQCICQDCCQ--EH 157
+P Q L E V+ R C H LS FC D+ +C C EH
Sbjct: 65 RPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEH 124
Query: 158 SGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEM 217
H L A + +LQ L+L RK +L + +K+V+ K EM
Sbjct: 125 RTHRTAPLQEAAGSYQVKLQMA-LELMRK-ELEDALTQEANVGKKTVIW-----KEKVEM 177
Query: 218 QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQEL-ERMAAIS 276
Q K + FL ++EQ L + ++A + +SK L ++ A+
Sbjct: 178 QRQRFRLEFEKHRG----FLAQEEQRQLRR---LEAEERATLQRLRESKSRLVQQSKALK 230
Query: 277 NTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 336
L+E C+ +GL L G+R V++ S EN +L+
Sbjct: 231 ELADELQERCQ----------RPALGL---LEGVRGVLSRSKAVTRLEAENIPMELK--- 274
Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396
T+ P RE ++ D+ DP TAH L L + R V
Sbjct: 275 --------------------TACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQ 314
Query: 397 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGL-TCKG-IDRKGE 454
+ PW P+ P RF W +L QS R+Y+EV + G G GL C+ + RKGE
Sbjct: 315 DGEPW-RDVPNNPERFDTWPCILGLQSFSSGRHYWEV-LVGEGAEWGLGVCQDTLPRKGE 372
Query: 455 ERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGV 511
S +G W L+ G E+ S L+ R +G+++D+ G +SFY V
Sbjct: 373 TTPSPENGVWALWLLK--GNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNV 427
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 89.0 bits (219), Expect = 1e-17
Identities = 103/450 (22%), Positives = 189/450 (42%), Gaps = 62/450 (13%)
Query: 93 CLTCMVNYCEEHLQPHQVNIKLQSHLLT---EPVKDHNWRYCPAHHSPLSAFCCPDQQCI 149
C C + ++L+P++ + ++L E + C H L FC D + +
Sbjct: 51 CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKAL 110
Query: 150 CQDCCQ--EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVS 207
C C Q +H H +V L+ A ++ + +LQ +L RK +L E + + +
Sbjct: 111 CWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKL-------EVEIAIK 163
Query: 208 VSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQ 267
++ K E Q + A + Q N FL E+EQ L + K E EK +
Sbjct: 164 RADWKKTVETQKSRIHAEFVQ-QKN---FLVEEEQRQLQELE--KDEREQLRILGEKEAK 217
Query: 268 ELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLEN 327
++ A+ + L+ C E + + + +++ E+
Sbjct: 218 LAQQSQALQELISELDRRCHSSALE---------------------LLQEVIIVLERSES 256
Query: 328 YKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLR 387
+ K + + E +R+ P ++ A IT DPDTA+ +L
Sbjct: 257 WNLKDLDITSPE---LRSVCHV------------PGLKKMLRTCAVHITLDPDTANPWLI 301
Query: 388 LQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTY-VGLTC 446
L E+ R+V + P RF + VL Q + ++Y+EV++ G + +G+
Sbjct: 302 LSEDRRQV-RLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR 360
Query: 447 KGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAG-PFRRLGVYIDFPGGI 505
+ RKG S SG W WN +++ A + +TPL P ++G+++D+ G+
Sbjct: 361 DSVRRKGHFLLSSKSGFWTIW--LWNKQKYEAG-TYPQTPLHLQVPPCQVGIFLDYEAGM 417
Query: 506 LSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534
+SFY + D +L++ F+ C F+ P+ F
Sbjct: 418 VSFYNIT-DHGSLIYSFSECAFTGPLRPFF 446
>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
Length = 517
Score = 86.7 bits (213), Expect = 5e-17
Identities = 100/416 (24%), Positives = 170/416 (40%), Gaps = 29/416 (6%)
Query: 131 CPAHHSPLSAFCCPDQQCICQDCC-QEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKL 189
CP H PL FC + +C+C C +E H LDA R +EA+L+ + +++
Sbjct: 95 CPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQ 154
Query: 190 NENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQAN 249
E + L+ + S + + +F LL A+ + +E + AL+QA
Sbjct: 155 AEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQAR 214
Query: 250 G----IKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKD 305
++ HLE + + ++ LE++ + FL+E + P +G
Sbjct: 215 DEEQRLRVHLEAVARHGCRIRELLEQV----DEQTFLQE-------SQLLQPPGPLG--- 260
Query: 306 KLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST- 364
L+ ++ + L QLL L E + A V+ P PST
Sbjct: 261 PLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAP-GPLAPVPSTV 319
Query: 365 ---REQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421
R + Q ++TFDP +A+++ L ++++V + + P P F W QV
Sbjct: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCR--QSRGPGGPGSFELW-QVQCA 376
Query: 422 QSLYLHRYYFEVEIFGAGTYVGLTCKGIDR-KGEERNSCISGNNFSWSLQWNGKEFTAWY 480
QS +Y+EV +G++ + R + I SW L AW+
Sbjct: 377 QSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWH 436
Query: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536
+ L R LG+ +D G L+FY +E T L + F F++P+ FWL
Sbjct: 437 NGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPL-YTFHALFNQPLTPVFWL 491
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 86.3 bits (212), Expect = 7e-17
Identities = 100/423 (23%), Positives = 176/423 (41%), Gaps = 51/423 (12%)
Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLK 188
C H P +C D + IC C +EH H ++ LD A ++ + L+ L+++L+
Sbjct: 130 CGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELE 189
Query: 189 LNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248
E S + K +L ++ + +F L A + + + ++ LEE + +
Sbjct: 190 DCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQ 249
Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEY----CKFKNTEDITFPSVYVGLK 304
N A L ++ K +++ A + + FL+E+ + N +V +K
Sbjct: 250 NENLAQLGVEITQLSKLSSQIQETAQKPD-LDFLQEFKSTLSRCSNVPGPKPTTVSSEMK 308
Query: 305 DKLSGIRKVITESTVHLIQLLENYKKKLQ-EFSKEEEYDIRTQVSAVVQRKYWTSKPEPS 363
+K+ + + T L +L+ +K+ L+ E KEE+ ++
Sbjct: 309 NKVWNV----SLKTFVLKGMLKKFKEDLRGELEKEEKVEL-------------------- 344
Query: 364 TREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQS 423
T DPDTA+ L L + + V P+ P RF +VL+
Sbjct: 345 ------------TLDPDTANPRLILSLDLKGV-RLGERAQDLPNHPCRFDTNTRVLASCG 391
Query: 424 LYLHRYYFEVEIFGA-GTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSD 482
R+++EVE+ G G+ + + RKG + G W+LQ NG ++ A S
Sbjct: 392 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEG---VWALQLNGGQYWAVTSP 448
Query: 483 METPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENA 542
+PL G R+ V +D G +SFY VE M ++ F F E V+ F +
Sbjct: 449 ERSPLSCGHLSRVRVALDLEVGAVSFYAVE--DMRHLYTFRVNFQERVFPLFSVCSTGTY 506
Query: 543 IRI 545
+RI
Sbjct: 507 LRI 509
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 85.9 bits (211), Expect = 9e-17
Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%)
Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129
++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R
Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173
Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186
C H ++ +C D Q IC C H H + +L + L+ +L ++
Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233
Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237
E +++L + V V+ S +A + L+ +++ + VM
Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293
Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286
+ +Q A + ++ + + E+ E ++ +K ER++ + + Q L
Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353
Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335
+T D TF + K L IR+ + ++ I + +
Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412
Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374
S E +Y I T + VV Q Y + T+ F+ A +
Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472
Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421
DP +AH+ L++ +N V P RF
Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531
Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479
++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L +
Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587
Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536
++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F +
Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643
Query: 537 SKK 539
K
Sbjct: 644 WNK 646
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 85.9 bits (211), Expect = 9e-17
Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%)
Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129
++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R
Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173
Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186
C H ++ +C D Q IC C H H + +L + L+ +L ++
Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233
Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237
E +++L + V V+ S +A + L+ +++ + VM
Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293
Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286
+ +Q A + ++ + + E+ E ++ +K ER++ + + Q L
Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353
Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335
+T D TF + K L IR+ + ++ I + +
Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412
Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374
S E +Y I T + VV Q Y + T+ F+ A +
Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472
Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421
DP +AH+ L++ +N V P RF
Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531
Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479
++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L +
Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587
Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536
++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F +
Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643
Query: 537 SKK 539
K
Sbjct: 644 WNK 646
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 85.9 bits (211), Expect = 9e-17
Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%)
Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129
++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R
Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173
Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186
C H ++ +C D Q IC C H H + +L + L+ +L ++
Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233
Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237
E +++L + V V+ S +A + L+ +++ + VM
Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293
Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286
+ +Q A + ++ + + E+ E ++ +K ER++ + + Q L
Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353
Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335
+T D TF + K L IR+ + ++ I + +
Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412
Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374
S E +Y I T + VV Q Y + T+ F+ A +
Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472
Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421
DP +AH+ L++ +N V P RF
Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531
Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479
++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L +
Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587
Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536
++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F +
Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643
Query: 537 SKK 539
K
Sbjct: 644 WNK 646
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 84.0 bits (206), Expect = 3e-16
Identities = 125/550 (22%), Positives = 214/550 (38%), Gaps = 93/550 (16%)
Query: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHN 127
A + + C FC D R AVK+C+TC V+YC+ L+ N K SH L EPV D +
Sbjct: 131 AMSSERIACQFCEQDPPR-DAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTH 189
Query: 128 WR--YCPAH-HSPLSAFCCPDQQCICQDC--CQEHSGHTIVSL----------------D 166
R C H + ++ +C D Q IC C H H + SL +
Sbjct: 190 LRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
Query: 167 AARRDKEAELQ-------CTQLDLE---RKLKLNENA---ISRLQANQKSVLVSVSEVKA 213
+R+ E E Q C Q+++ + KL E + +Q ++ + V + E K
Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
Query: 214 VAEMQFGELLAAVRKA--QANVML-----FLEEKEQAA-LSQANGIKAHLEYRSAEMEKS 265
+ + + +A R+ ++ V++ L+E +QA L A I + +A +
Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVL 369
Query: 266 KQELERMAAISN-TVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQ- 323
++ A N + F E + + +T P+ ++ + I TVH I
Sbjct: 370 IPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI---TVHWISD 426
Query: 324 ---LLENYKKKLQEFSKEEEY-------DIRTQVSAVVQRKYWTSKPEPSTREQFLQYAY 373
+ +Y+ + F+ + + D V + Q Y + TR F+ A
Sbjct: 427 DEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAI 486
Query: 374 D------------------ITFDPDTAHKYLRLQEEN---RKVTNTTPWEHPYPDLPSRF 412
+ DP HK L++ + K ++ H P RF
Sbjct: 487 NQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSH----TPERF 542
Query: 413 LHWRQVLSQQSLYLHR--YYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQ 470
+ ++++ +Y+EV + G+ T+ + GI K +N I N SW
Sbjct: 543 SGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAI---GIAYKSAPKNEWIGKNASSWVFS 598
Query: 471 WNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEP 529
F +++ E + P +RLGV +D+ +LSFY + +H F F P
Sbjct: 599 RCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFY--DPANSLHLHTFDVTFILP 656
Query: 530 VYAAFWLSKK 539
V F + K
Sbjct: 657 VCPTFTIWNK 666
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 77.0 bits (188), Expect = 4e-14
Identities = 104/431 (24%), Positives = 166/431 (38%), Gaps = 81/431 (18%)
Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLK 188
C H PL FC DQ+ +C C QEH H + +D A +L +Q +L K+K
Sbjct: 87 CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMK 146
Query: 189 LNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248
++ Q + + ++ K + Q + K FL E+E L +
Sbjct: 147 -------KVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHN----FLVEEEDLFLQRL 195
Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLS 308
N E E++K++L NT++ L ++
Sbjct: 196 N----------KEEEETKKKLNE-----NTLK----------------------LNQTIA 218
Query: 309 GIRKVITE----STVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST 364
++K+I E S ++LL+N K+ L ++ E D+ + AV K T P
Sbjct: 219 SLKKLILEVGEKSQAPTLELLQNPKEVL---TRSEIQDVNYSLEAV---KVKTVCQIPLM 272
Query: 365 REQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTP----------------WEHPYPD- 407
+E ++ + DTAH L +E R V NT W +P
Sbjct: 273 KEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTA 332
Query: 408 LPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSW 467
RF H VL + ++Y+EVE + C+ D G S +S + W
Sbjct: 333 FVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCRE-DVMGITDRSKMSPDVGIW 391
Query: 468 SLQWNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKF 526
++ W+ + TP + P R+GVY+D G +SFY D + L H F+C
Sbjct: 392 AIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSA-VDGVHL-HTFSCSS 449
Query: 527 SEPVYAAFWLS 537
+ FWLS
Sbjct: 450 VSRLRPFFWLS 460
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 75.9 bits (185), Expect = 9e-14
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Query: 371 YAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYY 430
+A D+T DPDTAH +L L E+++ V P+ RF W VL +++ R+Y
Sbjct: 301 HAVDVTLDPDTAHPHLFLYEDSKSV-RLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHY 359
Query: 431 FEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK- 488
+EVE+ + +G+ + + +KG + ++ N W+++ G + A + + TPL
Sbjct: 360 WEVEVGDRTDWAIGVCRENVMKKGFDP---MTPENGFWAVELYGNGYWA-LTPLRTPLPL 415
Query: 489 AGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL-SKKENAIRIVD 547
AGP RR+G+++D+ G +SFY + D + FS P+ F L S + + I
Sbjct: 416 AGPPRRVGIFLDYESGDISFYNMN-DGSDIYTFSNVTFSGPLRPFFCLWSSGKKPLTICP 474
Query: 548 LGEEPEK 554
+ + PE+
Sbjct: 475 IADGPER 481
>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
[Homo sapiens]
Length = 527
Score = 75.9 bits (185), Expect = 9e-14
Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 37/254 (14%)
Query: 305 DKLSGIRKVIT-----ESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSK 359
+KL +K+++ E I L E K+++Q KEEE ++ ++ ++ W
Sbjct: 270 NKLQKEKKILSGEKEFERETREIALKELEKERVQ---KEEELQVKEKLQEELR---W--- 320
Query: 360 PEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEH---PYPDLPSRFLHWR 416
R FL +A D+ DPDTAH L L E+ R V P+ H PD P RF
Sbjct: 321 -----RRTFL-HAVDVVLDPDTAHPDLFLSEDRRSV-RRCPFRHLGESVPDNPERFDSQP 373
Query: 417 QVLSQQSLYLHRYYFEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKE 475
VL ++S ++Y+EVE+ + VG+ ++RKGE I N F W+L+ + +
Sbjct: 374 CVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEV--LLIPQNGF-WTLEMHKGQ 430
Query: 476 FTAWYS-DMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVY 531
+ A S D PLK R+GV++D+ G +SFY + + H + C FS PV
Sbjct: 431 YRAVSSPDRILPLKES-LCRVGVFLDYEAGDVSFYNMRDRS----HIYTCPRSAFSVPVR 485
Query: 532 AAFWLSKKENAIRI 545
F L +++ I I
Sbjct: 486 PFFRLGCEDSPIFI 499
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 75.5 bits (184), Expect = 1e-13
Identities = 100/436 (22%), Positives = 167/436 (38%), Gaps = 65/436 (14%)
Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLD-----L 183
C H PL FC DQ+ +C C QEH H + +D A +D L
Sbjct: 87 CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRL 146
Query: 184 ERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQA 243
R L + +L +Q++++ + +V + +++ K ++ M E +
Sbjct: 147 IRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL 206
Query: 244 ALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGL 303
L+ + E E++K++L NT++ L
Sbjct: 207 HNFLVEEEDLFLQRLNKEEEETKKKLN-----ENTLK----------------------L 239
Query: 304 KDKLSGIRKVITE----STVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSK 359
++ ++K+I E S ++LL+N K+ L ++ E D+ + AV K T
Sbjct: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVL---TRSEIQDVNYSLEAV---KVKTVC 293
Query: 360 PEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTP----------------WEH 403
P +E ++ + DTAH L +E R V NT W +
Sbjct: 294 QIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 353
Query: 404 PYPD-LPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISG 462
P RF H VL + ++Y+EVE + C+ D G S +S
Sbjct: 354 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCRE-DVMGITDRSKMSP 412
Query: 463 NNFSWSLQWNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHK 521
+ W++ W+ + TP + P R+GVY+D G +SFY D + L H
Sbjct: 413 DVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSA-VDGVHL-HT 470
Query: 522 FACKFSEPVYAAFWLS 537
F+C + FWLS
Sbjct: 471 FSCSSVSRLRPFFWLS 486
>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
sapiens]
Length = 407
Score = 75.1 bits (183), Expect = 2e-13
Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 28/231 (12%)
Query: 322 IQLLENYKKKLQEFSK--EEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDP 379
I+ L+ KK L K +EE +I Q+ ++ W R FL +A D+ DP
Sbjct: 170 IKKLQREKKILSGEKKVEQEEKEIAQQLQEELR---W--------RRTFL-HAADVVLDP 217
Query: 380 DTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAG 439
DTAH L L E+ R V P+ PD P RF VL +S ++Y+EVE+
Sbjct: 218 DTAHPELFLSEDRRSV-RRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVM 276
Query: 440 TY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYS-DMETPLKAGPFRRLGV 497
+ VG+ ++RKGE I N F W+L+ G ++ A S + PLK R+GV
Sbjct: 277 VWTVGVCRHSVERKGEV--LLIPQNGF-WTLEMFGNQYRALSSPERILPLKES-LCRVGV 332
Query: 498 YIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVYAAFWLSKKENAIRI 545
++D+ G +SFY + + H + C F+ PV F L ++ I I
Sbjct: 333 FLDYEAGDVSFYNMRDRS----HIYTCPRSAFTVPVRPFFRLGSDDSPIFI 379
>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
sapiens]
Length = 523
Score = 75.1 bits (183), Expect = 2e-13
Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 28/231 (12%)
Query: 322 IQLLENYKKKLQEFSK--EEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDP 379
I+ L+ KK L K +EE +I Q+ ++ W R FL +A D+ DP
Sbjct: 286 IKKLQREKKILSGEKKVEQEEKEIAQQLQEELR---W--------RRTFL-HAADVVLDP 333
Query: 380 DTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAG 439
DTAH L L E+ R V P+ PD P RF VL +S ++Y+EVE+
Sbjct: 334 DTAHPELFLSEDRRSV-RRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVM 392
Query: 440 TY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYS-DMETPLKAGPFRRLGV 497
+ VG+ ++RKGE I N F W+L+ G ++ A S + PLK R+GV
Sbjct: 393 VWTVGVCRHSVERKGEV--LLIPQNGF-WTLEMFGNQYRALSSPERILPLKES-LCRVGV 448
Query: 498 YIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVYAAFWLSKKENAIRI 545
++D+ G +SFY + + H + C F+ PV F L ++ I I
Sbjct: 449 FLDYEAGDVSFYNMRDRS----HIYTCPRSAFTVPVRPFFRLGSDDSPIFI 495
>gi|4557743 Mediterranean fever protein [Homo sapiens]
Length = 781
Score = 74.7 bits (182), Expect = 2e-13
Identities = 118/537 (21%), Positives = 213/537 (39%), Gaps = 93/537 (17%)
Query: 30 PSPDSGSASPVEEEDVGSSEKL-GR--ETEEQDSDSAEQGDP------------------ 68
P+PD G+++ ++E + GR +T A++GDP
Sbjct: 281 PTPDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSG 340
Query: 69 ---AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKD 125
A + C C D R K+ S + C+ HL+ Q+
Sbjct: 341 HPQASGSRSPGCPRCQDSHER-KSPGSLSPQPLPQCKRHLKQVQL--------------- 384
Query: 126 HNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLER 185
+C H P+ C QEH GH + ++ + + ++Q LE
Sbjct: 385 ---LFCEDHDEPICLIC---------SLSQEHQGHRVRPIEEVALEHKKKIQ---KQLEH 429
Query: 186 KLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAA-VRKAQANVMLFLEEKEQAA 244
KL ++ + S E KAV+ ++ E L V++ V FLE++E
Sbjct: 430 LKKLRKSGEEQR---------SYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF 480
Query: 245 LSQANGIKAHL-EYRSAEMEKSKQELERMAAISNTVQFLE---EYCKFKNTEDITFPSVY 300
++ + + + R A + Q++ + A+ ++ E E+ ++ DI +
Sbjct: 481 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT 540
Query: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360
V + +K + +++ + IQLL + +++ +K +R+++ + P
Sbjct: 541 VPVPEKWTTPQEIKQK-----IQLLHQKSEFVEKSTKYFSETLRSEMEMF-------NVP 588
Query: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420
E + +A ++ D +TA+ L ++ + V WE PD P RF VL
Sbjct: 589 ELIGAQA---HAVNVILDAETAYPNLIFSDDLKSVRLGNKWER-LPDGPQRFDSCIIVLG 644
Query: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCK-GIDRKGEERNSCISGNNFSWS-LQWNGKEFTA 478
S R Y+EVE+ ++ CK I RKG N +S N W + E+ A
Sbjct: 645 SPSFLSGRRYWEVEVGDKTAWILGACKTSISRKG---NMTLSPENGYWVVIMMKENEYQA 701
Query: 479 WYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534
L P +R+G+++D+ G +SFY V + ++ FA C FS P+ F
Sbjct: 702 SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNV--TARSHIYTFASCSFSGPLQPIF 756
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 74.3 bits (181), Expect = 3e-13
Identities = 101/472 (21%), Positives = 187/472 (39%), Gaps = 83/472 (17%)
Query: 92 SCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWR---YCPAHHSPLSAFCCPDQQC 148
SC C ++Y EHLQ +Q + L + N + C H L FC D++
Sbjct: 55 SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKV 114
Query: 149 ICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLV 206
IC C QEH GH V + ++ + +LQ L+++ + E + ++ + S
Sbjct: 115 ICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKY 174
Query: 207 SVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSK 266
V + + +F +L + + + + LEE+E+ L ++ AE E +
Sbjct: 175 QVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLD---------KFAEAEDELVQ 225
Query: 267 QELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLE 326
Q+ + + + + V+ ++ + +D +SGI K S + ++ +
Sbjct: 226 QK-QLVRELISDVECRSQWSTMELLQD-------------MSGIMK---WSEIWRLKKPK 268
Query: 327 NYKKKLQEFSKEEEYDIRTQV--SAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHK 384
KKL+ + Q+ R YW D+T + +
Sbjct: 269 MVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV----------------DVTLNSVNLNL 312
Query: 385 YLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYV-G 443
L L E+ R+V + W P + ++ VL Q ++Y+EV++ ++ G
Sbjct: 313 NLVLSEDQRQVISVPIW-------PFQCYNY-GVLGSQYFSSGKHYWEVDVSKKTAWILG 364
Query: 444 LTCKGIDRKGE-ERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFR--------- 493
+ C+ R + C + N + F W ++ K G F
Sbjct: 365 VYCRTYSRHMKYVVRRCANRQNLYTKYR---PLFGYWVIGLQNKCKYGVFEESLSSDPEV 421
Query: 494 ----------RLGVYIDFPGGILSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534
R+GV++D+ GI+SF+ V +L++KF+ C FS+PVY F
Sbjct: 422 LTLSMAVPPCRVGVFLDYEAGIVSFFNVT-SHGSLIYKFSKCCFSQPVYPYF 472
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,521,729
Number of Sequences: 37866
Number of extensions: 1188821
Number of successful extensions: 10115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 290
Number of HSP's that attempted gapping in prelim test: 9156
Number of HSP's gapped (non-prelim): 1046
length of query: 564
length of database: 18,247,518
effective HSP length: 108
effective length of query: 456
effective length of database: 14,157,990
effective search space: 6456043440
effective search space used: 6456043440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.