BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|48255913 tripartite motif-containing 16 [Homo sapiens] (564 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|48255913 tripartite motif-containing 16 [Homo sapiens] 1156 0.0 gi|82617564 tripartite motif-containing 16-like [Homo sapiens] 697 0.0 gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ... 371 e-102 gi|54792146 tripartite motif-containing 47 [Homo sapiens] 173 3e-43 gi|68160937 tripartite motif-containing 25 [Homo sapiens] 155 9e-38 gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] 145 1e-34 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 122 7e-28 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 119 6e-27 gi|5730009 ret finger protein [Homo sapiens] 112 1e-24 gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21 gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21 gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ... 101 2e-21 gi|21630277 tripartite motif-containing 11 [Homo sapiens] 99 1e-20 gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 92 1e-18 gi|112421127 tripartite motif-containing 58 [Homo sapiens] 91 2e-18 gi|15208660 tripartite motif protein 21 [Homo sapiens] 89 1e-17 gi|38679905 tripartite motif-containing 65 [Homo sapiens] 87 5e-17 gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 86 7e-17 gi|148833499 midline 1 [Homo sapiens] 86 9e-17 gi|4557753 midline 1 [Homo sapiens] 86 9e-17 gi|15451852 midline 1 [Homo sapiens] 86 9e-17 gi|223890259 midline 2 isoform 2 [Homo sapiens] 84 3e-16 gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 77 4e-14 gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 76 9e-14 gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur... 76 9e-14 gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 75 1e-13 gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo... 75 2e-13 gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ... 75 2e-13 gi|4557743 Mediterranean fever protein [Homo sapiens] 75 2e-13 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 74 3e-13 >gi|48255913 tripartite motif-containing 16 [Homo sapiens] Length = 564 Score = 1156 bits (2991), Expect = 0.0 Identities = 564/564 (100%), Positives = 564/564 (100%) Query: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS Sbjct: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60 Query: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT Sbjct: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120 Query: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ 180 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ Sbjct: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQ 180 Query: 181 LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK 240 LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK Sbjct: 181 LDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEK 240 Query: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY 300 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY Sbjct: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVY 300 Query: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP Sbjct: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360 Query: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS Sbjct: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420 Query: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY 480 QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY Sbjct: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWY 480 Query: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE 540 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE Sbjct: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKE 540 Query: 541 NAIRIVDLGEEPEKPAPSLVGTAP 564 NAIRIVDLGEEPEKPAPSLVGTAP Sbjct: 541 NAIRIVDLGEEPEKPAPSLVGTAP 564 >gi|82617564 tripartite motif-containing 16-like [Homo sapiens] Length = 348 Score = 697 bits (1800), Expect = 0.0 Identities = 339/348 (97%), Positives = 345/348 (99%) Query: 217 MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAIS 276 MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELE MAAIS Sbjct: 1 MQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELETMAAIS 60 Query: 277 NTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 336 NTVQFLEEYCKFKNTEDITFPSVY+GLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS Sbjct: 61 NTVQFLEEYCKFKNTEDITFPSVYIGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 120 Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396 KEEEYDIRTQVSA+VQRKYWTSKPEPSTREQFLQY +DITFDPDTAHKYLRLQEENRKVT Sbjct: 121 KEEEYDIRTQVSAIVQRKYWTSKPEPSTREQFLQYVHDITFDPDTAHKYLRLQEENRKVT 180 Query: 397 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEER 456 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGID+KGEER Sbjct: 181 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDQKGEER 240 Query: 457 NSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTM 516 +SCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPF RLGVYIDFPGGILSFYGVEYD+M Sbjct: 241 SSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFWRLGVYIDFPGGILSFYGVEYDSM 300 Query: 517 TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP 564 TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP Sbjct: 301 TLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP 348 >gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo sapiens] Length = 282 Score = 371 bits (952), Expect = e-102 Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS Sbjct: 1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS 60 Query: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT Sbjct: 61 DSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLT 120 Query: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE 173 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE Sbjct: 121 EPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKE 173 >gi|54792146 tripartite motif-containing 47 [Homo sapiens] Length = 638 Score = 173 bits (439), Expect = 3e-43 Identities = 147/543 (27%), Positives = 238/543 (43%), Gaps = 73/543 (13%) Query: 9 PGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDP 68 PGP P +P AP SA P E + A + P Sbjct: 89 PGPAPALAPEPSAP-------------SALP--------------SVPEPSAPCAPEPWP 121 Query: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNW 128 AGE + V CD C + + A SCL+C+ ++C HL PH+ + L+ H L P++ Sbjct: 122 AGE-EPVRCDACPEGAA-LPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEE 179 Query: 129 RYCPAHHSPLSAFCCPDQQCICQDC-CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKL 187 CP H PL +C ++ C+C+ C QEH GH +V L+ R +EAE + L Sbjct: 180 SLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAE-------QSKVL 232 Query: 188 KLNENAISRLQAN--QKSVLVSVSEVKAVAEMQ-----FGELLAAVRKAQANVMLFLEEK 240 E+ + L A Q V++ + AVAE + F + AA++ Q V+ F+EE Sbjct: 233 SAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEG 292 Query: 241 EQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK-NTEDITFPS- 298 E A L ++ G E + + + +++Q L ++ +++V FL+E + ED P Sbjct: 293 EAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSVSFLQELLALRLALEDGCGPGP 351 Query: 299 ------VYVGLKDKLSGIRKVITESTVHLIQLL------ENYKKKLQEFSKEEEYDIRTQ 346 + + +R ++ + V+ + L E+ +KL + E D+ + Sbjct: 352 GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLEST 411 Query: 347 VSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYP 406 + R+ FL++AY + D DTA K+L+L K YP Sbjct: 412 ----------NLLESEAPRDYFLKFAYIVDLDSDTADKFLQL--FGTKGVKRVLCPINYP 459 Query: 407 DLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFS 466 P+RF H QVL + +L YY+EVEI +G+ + + + N S Sbjct: 460 LSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHS 519 Query: 467 WSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKF 526 LQWNG+ F+ W+ +E PL +GV +++ L+FY V M+L+ + K Sbjct: 520 CCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRL--KA 577 Query: 527 SEP 529 S P Sbjct: 578 SRP 580 >gi|68160937 tripartite motif-containing 25 [Homo sapiens] Length = 630 Score = 155 bits (392), Expect = 9e-38 Identities = 131/522 (25%), Positives = 225/522 (43%), Gaps = 67/522 (12%) Query: 74 EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133 +V CD CL + AVK+CL CM ++C+EHLQPH + Q H L PV+D R C Sbjct: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159 Query: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENA 193 H+ FC +CIC C EH + SL A D EA L+ + ++ A Sbjct: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRA 219 Query: 194 ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKA 253 + ++ Q+ V ++ + + ++ E+ A + ++ ++E+E+ S+ + I Sbjct: 220 LDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQ 279 Query: 254 HLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK--NTEDITFPSVY----------- 300 L + +E++ K+E+E+ + +FLE+ K + +T+ + P V Sbjct: 280 ILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQ 339 Query: 301 --VGLKDKLSGIRKVITEST--------------------VHLIQLLENYKKK------- 331 + LK++L + E T V + E KK Sbjct: 340 STIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPAL 399 Query: 332 ---LQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST-------------REQFLQYAYDI 375 L F E+ Q K +S P ++ R + L+Y + Sbjct: 400 PSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKV 459 Query: 376 TFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI 435 D +TAH + L E V + Y P RF + QVL +Y+EVE+ Sbjct: 460 ILDYNTAHNKVALSE-CYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518 Query: 436 FGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRR 494 VG+ ++R+G E S + N+ SW ++W + +AW++++E L + R Sbjct: 519 QKNNFCGVGICYGSMNRQGPE--SRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATR 576 Query: 495 LGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536 +GV ++ G + F+ V D + L++KF F+E +Y AFW+ Sbjct: 577 VGVLLNCDHGFVIFFAVA-DKVHLMYKFRVDFTEALYPAFWV 617 >gi|17402909 tripartite motif protein TRIM29 [Homo sapiens] Length = 588 Score = 145 bits (366), Expect = 1e-34 Identities = 76/214 (35%), Positives = 120/214 (56%), Gaps = 3/214 (1%) Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCP 132 +EVLCD C+ + + KAVKSCL C ++CE HL+PH + H L EP++D R CP Sbjct: 169 EEVLCDSCIGNKQ--KAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCP 226 Query: 133 AHHSPLSAFCCPDQQCICQDCC-QEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNE 191 H + FC DQ CIC C QEH H+ V+++ A+ +KE EL + L+ K+ E Sbjct: 227 VHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIE 286 Query: 192 NAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGI 251 + + Q + + + KA+ E F +L+ + K + V LE++EQ A+ Q I Sbjct: 287 DEAEKWQKEKDRIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVI 346 Query: 252 KAHLEYRSAEMEKSKQELERMAAISNTVQFLEEY 285 L+ R+ + + KQ E++ +IS++V FL+E+ Sbjct: 347 MDALDERAKVLHEDKQTREQLHSISDSVLFLQEF 380 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 122 bits (307), Expect = 7e-28 Identities = 126/464 (27%), Positives = 214/464 (46%), Gaps = 54/464 (11%) Query: 93 CLTCMVNYCEEHLQPHQ-----VNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQ 147 C C L+P++ V I Q + ++D + CP HH LS FC DQ+ Sbjct: 66 CPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDES--LCPQHHEALSLFCYEDQE 123 Query: 148 CICQDCCQEHS--GHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVL 205 +C C H+ HT+V LD A ++ + +LQ LE+KL+ I+R +++++ Sbjct: 124 AVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQ----EITRCKSSEEK-- 177 Query: 206 VSVSEVKAVAEM-------QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYR 258 E+K + E +F EL + + Q ++ LEE+EQ L + AHL + Sbjct: 178 -KPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDK 236 Query: 259 SAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITEST 318 ++ E+E S E K+T + P + G LS I ++ Sbjct: 237 RRDLAHLAAEVEGKCLQSG----FEMLKDVKSTLEKNIPRKFGG---SLSTICPRDHKAL 289 Query: 319 VHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEP--STREQFLQYAYDIT 376 + L+ K++ K + ++ T VS +++ + ++ P + R+ Q D+T Sbjct: 290 LGLV-------KEINRCEKVKTMEV-TSVSIELEKNF-SNFPRQYFALRKILKQLIADVT 340 Query: 377 FDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIF 436 DP+TAH L L E+ + V PD P RF + VL+ + R+Y+EVE+ Sbjct: 341 LDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEV- 399 Query: 437 GAGTY--VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPL--KAGP 491 G T+ VG+ + RKGE +G W ++ WNG ++ A + TPL K P Sbjct: 400 GDKTHWAVGVCRDSVSRKGELTPLPETG---YWRVRLWNGDKYAATTTPF-TPLHIKVKP 455 Query: 492 FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFW 535 +R+G+++D+ G LSFY V + ++ F F+E ++ F+ Sbjct: 456 -KRVGIFLDYEAGTLSFYNV--TDRSHIYTFTDTFTEKLWPLFY 496 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 119 bits (299), Expect = 6e-27 Identities = 123/462 (26%), Positives = 202/462 (43%), Gaps = 80/462 (17%) Query: 93 CLTCMVNYCEEHLQPHQ-----VNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQ 147 C C L+P++ V I Q + ++D + CP HH LS FC DQ+ Sbjct: 66 CPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDES--LCPQHHEALSLFCYEDQE 123 Query: 148 CICQDCCQEHS--GHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVL 205 +C C H+ HT+V LD A ++ + +LQ LE+KL+ I+R +++++ Sbjct: 124 AVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQ----EITRCKSSEEK-- 177 Query: 206 VSVSEVKAVAEM-------QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYR 258 E+K + E +F EL + + Q ++ LEE+EQ L + AHL + Sbjct: 178 -KPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDK 236 Query: 259 SAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITEST 318 +++L +AA E S + LKD S + K T Sbjct: 237 -------RRDLAHLAA---------------EVEGKCLQSGFEMLKDVKSTLEKCEKVKT 274 Query: 319 VHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFD 378 + + + +K F R+Y+ + R+ Q D+T D Sbjct: 275 MEVTSVSIELEKNFSNFP----------------RQYF------ALRKILKQLIADVTLD 312 Query: 379 PDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGA 438 P+TAH L L E+ + V PD P RF + VL+ + R+Y+EVE+ G Sbjct: 313 PETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEV-GD 371 Query: 439 GTY--VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPL--KAGPFR 493 T+ VG+ + RKGE +G W ++ WNG ++ A + TPL K P + Sbjct: 372 KTHWAVGVCRDSVSRKGELTPLPETG---YWRVRLWNGDKYAATTTPF-TPLHIKVKP-K 426 Query: 494 RLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFW 535 R+G+++D+ G LSFY V + ++ F F+E ++ F+ Sbjct: 427 RVGIFLDYEAGTLSFYNV--TDRSHIYTFTDTFTEKLWPLFY 466 >gi|5730009 ret finger protein [Homo sapiens] Length = 513 Score = 112 bits (279), Expect = 1e-24 Identities = 121/478 (25%), Positives = 213/478 (44%), Gaps = 63/478 (13%) Query: 92 SCLTCMVNYCEEHLQP--HQVNI-KLQSHLLTEPVKDHNWRY--CPAHHSPLSAFCCPDQ 146 SC C + + H++P H N+ +L L TE C H PL +C DQ Sbjct: 52 SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQ 111 Query: 147 QCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQ-KS 203 IC C +EH GH+++ L+ A + ++Q QLD +++K + R Q Q ++ Sbjct: 112 MPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQ-NQLDHLKRVK-DLKKRRRAQGEQARA 169 Query: 204 VLVSVSEVKAVAEM-QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIK-------AHL 255 L+S+++++ + +F +L ++++ + ++ LEE + A + NG +HL Sbjct: 170 ELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHL 229 Query: 256 EYRSAEMEKSKQELER--MAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKV 313 A++E+ +Q+ R + I +T+ E I P ++ D I + Sbjct: 230 SSLIAQLEEKQQQPTRELLQDIGDTLS---------RAERIRIPEPWITPPDLQEKIH-I 279 Query: 314 ITESTVHLIQLLENYKKKLQ-EFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYA 372 + + L + L+ + +K+Q + K +E RE L Y+ Sbjct: 280 FAQKCLFLTESLKQFTEKMQSDMEKIQEL-----------------------REAQL-YS 315 Query: 373 YDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFE 432 D+T DPDTA+ L L + R+V + + PD P RF + VL R+Y+E Sbjct: 316 VDVTLDPDTAYPSLILSDNLRQVRYSY-LQQDLPDNPERFNLFPCVLGSPCFIAGRHYWE 374 Query: 433 VEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQ-WNGKEFTAWYSDMETPLKAG 490 VE+ + +G+ + RKG ++ +G W++ W GKE+ A S M Sbjct: 375 VEVGDKAKWTIGVCEDSVCRKGGVTSAPQNG---FWAVSLWYGKEYWALTSPMTALPLRT 431 Query: 491 PFRRLGVYIDFPGGILSFYGV--EYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIV 546 P +R+G+++D+ G +SFY V T T H C P ++ + K A I+ Sbjct: 432 PLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLII 489 >gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 101 bits (252), Expect = 2e-21 Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%) Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175 +E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++ Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72 Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229 +C QL ++++ ++ E+A +L+AN +S K + +F EL + + Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125 Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279 +A F+++ Q L QA+ + L+ R + + ++R+ A + T Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185 Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336 Q +++ P + +K G+ + + EST+ I+L E+ +L + S Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243 Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396 T+ +++ + P P R L+YA T DPDT H LRL + V Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290 Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453 P P L RF QVL++ R+Y+EV++ GAG +VG + R+G Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348 Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512 + + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408 Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536 M+ +H F F EP+Y A L Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431 >gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 101 bits (252), Expect = 2e-21 Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%) Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175 +E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++ Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72 Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229 +C QL ++++ ++ E+A +L+AN +S K + +F EL + + Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125 Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279 +A F+++ Q L QA+ + L+ R + + ++R+ A + T Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185 Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336 Q +++ P + +K G+ + + EST+ I+L E+ +L + S Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243 Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396 T+ +++ + P P R L+YA T DPDT H LRL + V Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290 Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453 P P L RF QVL++ R+Y+EV++ GAG +VG + R+G Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348 Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512 + + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408 Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536 M+ +H F F EP+Y A L Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431 >gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo sapiens] Length = 442 Score = 101 bits (252), Expect = 2e-21 Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%) Query: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175 +E V+ WR CP H ++ FC ++C+C C H GH + ++L+AA ++ Sbjct: 14 SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72 Query: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229 +C QL ++++ ++ E+A +L+AN +S K + +F EL + + Sbjct: 73 QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125 Query: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279 +A F+++ Q L QA+ + L+ R + + ++R+ A + T Sbjct: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185 Query: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336 Q +++ P + +K G+ + + EST+ I+L E+ +L + S Sbjct: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243 Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396 T+ +++ + P P R L+YA T DPDT H LRL + V Sbjct: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290 Query: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453 P P L RF QVL++ R+Y+EV++ GAG +VG + R+G Sbjct: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348 Query: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512 + + N SW L+ E+ A++ + L+ RLGV++D+ G+L+FY V Sbjct: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408 Query: 513 YDTMTLVHKFACKFSEPVYAAFWL 536 M+ +H F F EP+Y A L Sbjct: 409 -GGMSHLHTFRATFQEPLYPALRL 431 >gi|21630277 tripartite motif-containing 11 [Homo sapiens] Length = 468 Score = 99.0 bits (245), Expect = 1e-20 Identities = 110/445 (24%), Positives = 188/445 (42%), Gaps = 73/445 (16%) Query: 78 DFCLDDTRRV----KAVKSCLTCMVNYCEEHLQPHQVNIKL-QSHLLTEPVKDHNWRYCP 132 +FC + RR + +C C + +L+P++ K+ + P CP Sbjct: 34 NFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCP 93 Query: 133 AHHSPLSAFCCPDQQCICQDCCQ--EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLN 190 AH PL+AFC + + +C C + EH H + L A D +A+L+ + L ++++ Sbjct: 94 AHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQ-- 151 Query: 191 ENAISRLQANQKSVLVS--VSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248 + + + QA++ VL V + +F L + + + ++ LEE+E L + Sbjct: 152 DALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRL 211 Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLS 308 AHL +SA + + ELE + Sbjct: 212 REGAAHLGQQSAHLAELIAELEGRCQLP-------------------------------- 239 Query: 309 GIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQF 368 + LL++ K L+ D++ Q VV + T P E Sbjct: 240 ------------ALGLLQDIKDALRRVQ-----DVKLQPPEVVPMELRTVCRVPGLVETL 282 Query: 369 LQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHR 428 ++ D+T DPDTA+ L L E+ R V PD P RF VL Q+ R Sbjct: 283 RRFRGDVTLDPDTANPELILSEDRRSV-QRGDLRQALPDSPERFDPGPCVLGQERFTSGR 341 Query: 429 YYFEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDME--- 484 +Y+EVE+ ++ +G+ + ++RK E+ +GN F W L + G ++Y+ E Sbjct: 342 HYWEVEVGDRTSWALGVCRENVNRK--EKGELSAGNGF-WILVFLG----SYYNSSERAL 394 Query: 485 TPLKAGPFRRLGVYIDFPGGILSFY 509 PL+ P RR+G+++D+ G LSFY Sbjct: 395 APLRDPP-RRVGIFLDYEAGHLSFY 418 >gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] Length = 630 Score = 92.0 bits (227), Expect = 1e-18 Identities = 113/453 (24%), Positives = 173/453 (38%), Gaps = 89/453 (19%) Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQC------TQLD 182 CP H L FC D++ IC C + H H++V L+ ++ +A+LQ L+ Sbjct: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286 Query: 183 LERKLKLNENA-ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKE 241 +K+K E ++ L++ KS L +V+ +FG L + + QA + L E Sbjct: 287 AVQKMKAKEERRVTELKSQMKSELAAVAS-------EFGRLTRFLAEEQAGLERRLREMH 339 Query: 242 QAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYV 301 +A L +A + L ++A++ + E + + + F E++ V Sbjct: 340 EAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEV 399 Query: 302 GLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPE 361 D + +D T A+V++ Sbjct: 400 WSPDPC-----------------------------QPHSHDFLTD--AIVRKM------- 421 Query: 362 PSTREQFLQYA-YDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420 F Q A D+T DPDTAH L L + R V D P RF VL Sbjct: 422 ---SRMFCQAARVDLTLDPDTAHPALMLSPDRRGV-RLAERRQEVADHPKRFSADCCVLG 477 Query: 421 QQSLYLHRYYFEVEIFGA-GTYVGLTCKGIDRK---GEERNSCISGNNFS---------- 466 Q R+Y+EVE+ G G VG + K G +S SG+ S Sbjct: 478 AQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRL 537 Query: 467 ------------WSLQWNGKEFTAWYSDMETPLKAGPF-RRLGVYIDFPGGILSFYGVEY 513 W + NGK + A S +T L RR GVY+D+ G L FY E Sbjct: 538 HLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE- 596 Query: 514 DTMTLVHKFACKF-SEPVYAAFWLSKKENAIRI 545 T+ VH F+ F E V+ F + K I++ Sbjct: 597 -TLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628 >gi|112421127 tripartite motif-containing 58 [Homo sapiens] Length = 486 Score = 91.3 bits (225), Expect = 2e-18 Identities = 123/477 (25%), Positives = 184/477 (38%), Gaps = 87/477 (18%) Query: 68 PAGEG--KEVLCDFCLDDTRRVKAVKS----CLTCMVNYCEEH----------------L 105 P GE ++ C CLD + +V CL C+ +CE+ Sbjct: 5 PPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPF 64 Query: 106 QPHQVNIKLQSHLLTEPVK------DHNWRYCPAHHSPLSAFCCPDQQCICQDCCQ--EH 157 +P Q L E V+ R C H LS FC D+ +C C EH Sbjct: 65 RPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEH 124 Query: 158 SGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEM 217 H L A + +LQ L+L RK +L + +K+V+ K EM Sbjct: 125 RTHRTAPLQEAAGSYQVKLQMA-LELMRK-ELEDALTQEANVGKKTVIW-----KEKVEM 177 Query: 218 QFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQEL-ERMAAIS 276 Q K + FL ++EQ L + ++A + +SK L ++ A+ Sbjct: 178 QRQRFRLEFEKHRG----FLAQEEQRQLRR---LEAEERATLQRLRESKSRLVQQSKALK 230 Query: 277 NTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFS 336 L+E C+ +GL L G+R V++ S EN +L+ Sbjct: 231 ELADELQERCQ----------RPALGL---LEGVRGVLSRSKAVTRLEAENIPMELK--- 274 Query: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396 T+ P RE ++ D+ DP TAH L L + R V Sbjct: 275 --------------------TACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQ 314 Query: 397 NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGL-TCKG-IDRKGE 454 + PW P+ P RF W +L QS R+Y+EV + G G GL C+ + RKGE Sbjct: 315 DGEPW-RDVPNNPERFDTWPCILGLQSFSSGRHYWEV-LVGEGAEWGLGVCQDTLPRKGE 372 Query: 455 ERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGV 511 S +G W L+ G E+ S L+ R +G+++D+ G +SFY V Sbjct: 373 TTPSPENGVWALWLLK--GNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNV 427 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 89.0 bits (219), Expect = 1e-17 Identities = 103/450 (22%), Positives = 189/450 (42%), Gaps = 62/450 (13%) Query: 93 CLTCMVNYCEEHLQPHQVNIKLQSHLLT---EPVKDHNWRYCPAHHSPLSAFCCPDQQCI 149 C C + ++L+P++ + ++L E + C H L FC D + + Sbjct: 51 CPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKAL 110 Query: 150 CQDCCQ--EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVS 207 C C Q +H H +V L+ A ++ + +LQ +L RK +L E + + + Sbjct: 111 CWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKL-------EVEIAIK 163 Query: 208 VSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQ 267 ++ K E Q + A + Q N FL E+EQ L + K E EK + Sbjct: 164 RADWKKTVETQKSRIHAEFVQ-QKN---FLVEEEQRQLQELE--KDEREQLRILGEKEAK 217 Query: 268 ELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLEN 327 ++ A+ + L+ C E + + + +++ E+ Sbjct: 218 LAQQSQALQELISELDRRCHSSALE---------------------LLQEVIIVLERSES 256 Query: 328 YKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLR 387 + K + + E +R+ P ++ A IT DPDTA+ +L Sbjct: 257 WNLKDLDITSPE---LRSVCHV------------PGLKKMLRTCAVHITLDPDTANPWLI 301 Query: 388 LQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTY-VGLTC 446 L E+ R+V + P RF + VL Q + ++Y+EV++ G + +G+ Sbjct: 302 LSEDRRQV-RLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR 360 Query: 447 KGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAG-PFRRLGVYIDFPGGI 505 + RKG S SG W WN +++ A + +TPL P ++G+++D+ G+ Sbjct: 361 DSVRRKGHFLLSSKSGFWTIW--LWNKQKYEAG-TYPQTPLHLQVPPCQVGIFLDYEAGM 417 Query: 506 LSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534 +SFY + D +L++ F+ C F+ P+ F Sbjct: 418 VSFYNIT-DHGSLIYSFSECAFTGPLRPFF 446 >gi|38679905 tripartite motif-containing 65 [Homo sapiens] Length = 517 Score = 86.7 bits (213), Expect = 5e-17 Identities = 100/416 (24%), Positives = 170/416 (40%), Gaps = 29/416 (6%) Query: 131 CPAHHSPLSAFCCPDQQCICQDCC-QEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKL 189 CP H PL FC + +C+C C +E H LDA R +EA+L+ + +++ Sbjct: 95 CPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQ 154 Query: 190 NENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQAN 249 E + L+ + S + + +F LL A+ + +E + AL+QA Sbjct: 155 AEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQAR 214 Query: 250 G----IKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKD 305 ++ HLE + + ++ LE++ + FL+E + P +G Sbjct: 215 DEEQRLRVHLEAVARHGCRIRELLEQV----DEQTFLQE-------SQLLQPPGPLG--- 260 Query: 306 KLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST- 364 L+ ++ + L QLL L E + A V+ P PST Sbjct: 261 PLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAP-GPLAPVPSTV 319 Query: 365 ---REQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421 R + Q ++TFDP +A+++ L ++++V + + P P F W QV Sbjct: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCR--QSRGPGGPGSFELW-QVQCA 376 Query: 422 QSLYLHRYYFEVEIFGAGTYVGLTCKGIDR-KGEERNSCISGNNFSWSLQWNGKEFTAWY 480 QS +Y+EV +G++ + R + I SW L AW+ Sbjct: 377 QSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWH 436 Query: 481 SDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536 + L R LG+ +D G L+FY +E T L + F F++P+ FWL Sbjct: 437 NGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPL-YTFHALFNQPLTPVFWL 491 >gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] Length = 511 Score = 86.3 bits (212), Expect = 7e-17 Identities = 100/423 (23%), Positives = 176/423 (41%), Gaps = 51/423 (12%) Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLK 188 C H P +C D + IC C +EH H ++ LD A ++ + L+ L+++L+ Sbjct: 130 CGQHGEPFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELE 189 Query: 189 LNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248 E S + K +L ++ + +F L A + + + ++ LEE + + Sbjct: 190 DCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQ 249 Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEY----CKFKNTEDITFPSVYVGLK 304 N A L ++ K +++ A + + FL+E+ + N +V +K Sbjct: 250 NENLAQLGVEITQLSKLSSQIQETAQKPD-LDFLQEFKSTLSRCSNVPGPKPTTVSSEMK 308 Query: 305 DKLSGIRKVITESTVHLIQLLENYKKKLQ-EFSKEEEYDIRTQVSAVVQRKYWTSKPEPS 363 +K+ + + T L +L+ +K+ L+ E KEE+ ++ Sbjct: 309 NKVWNV----SLKTFVLKGMLKKFKEDLRGELEKEEKVEL-------------------- 344 Query: 364 TREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQS 423 T DPDTA+ L L + + V P+ P RF +VL+ Sbjct: 345 ------------TLDPDTANPRLILSLDLKGV-RLGERAQDLPNHPCRFDTNTRVLASCG 391 Query: 424 LYLHRYYFEVEIFGA-GTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSD 482 R+++EVE+ G G+ + + RKG + G W+LQ NG ++ A S Sbjct: 392 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEG---VWALQLNGGQYWAVTSP 448 Query: 483 METPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENA 542 +PL G R+ V +D G +SFY VE M ++ F F E V+ F + Sbjct: 449 ERSPLSCGHLSRVRVALDLEVGAVSFYAVE--DMRHLYTFRVNFQERVFPLFSVCSTGTY 506 Query: 543 IRI 545 +RI Sbjct: 507 LRI 509 >gi|148833499 midline 1 [Homo sapiens] Length = 667 Score = 85.9 bits (211), Expect = 9e-17 Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%) Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129 ++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173 Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186 C H ++ +C D Q IC C H H + +L + L+ +L ++ Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233 Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237 E +++L + V V+ S +A + L+ +++ + VM Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293 Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286 + +Q A + ++ + + E+ E ++ +K ER++ + + Q L Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353 Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335 +T D TF + K L IR+ + ++ I + + Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412 Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374 S E +Y I T + VV Q Y + T+ F+ A + Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472 Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421 DP +AH+ L++ +N V P RF Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531 Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479 ++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L + Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587 Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536 ++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F + Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643 Query: 537 SKK 539 K Sbjct: 644 WNK 646 >gi|4557753 midline 1 [Homo sapiens] Length = 667 Score = 85.9 bits (211), Expect = 9e-17 Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%) Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129 ++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173 Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186 C H ++ +C D Q IC C H H + +L + L+ +L ++ Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233 Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237 E +++L + V V+ S +A + L+ +++ + VM Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293 Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286 + +Q A + ++ + + E+ E ++ +K ER++ + + Q L Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353 Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335 +T D TF + K L IR+ + ++ I + + Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412 Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374 S E +Y I T + VV Q Y + T+ F+ A + Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472 Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421 DP +AH+ L++ +N V P RF Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531 Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479 ++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L + Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587 Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536 ++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F + Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643 Query: 537 SKK 539 K Sbjct: 644 WNK 646 >gi|15451852 midline 1 [Homo sapiens] Length = 667 Score = 85.9 bits (211), Expect = 9e-17 Identities = 119/543 (21%), Positives = 213/543 (39%), Gaps = 87/543 (16%) Query: 73 KEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHNWR-- 129 ++VLC FC D + AVK+C+TC V+YC+E L+ N K H L EP+ D + R Sbjct: 115 EKVLCQFCDQDPAQ-DAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGL 173 Query: 130 YCPAHHSP-LSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERK 186 C H ++ +C D Q IC C H H + +L + L+ +L ++ Sbjct: 174 MCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKR 233 Query: 187 LKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA---------QANVMLFL 237 E +++L + V V+ S +A + L+ +++ + VM Sbjct: 234 NTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLR 293 Query: 238 EEKEQAA-----LSQANGIKAHLEYRSAE------MEKSKQELERMAAISNTVQFLEEYC 286 + +Q A + ++ + + E+ E ++ +K ER++ + + Q L Sbjct: 294 KLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEI 353 Query: 287 KFKNTEDITFPSVYVGLKDKLS-----------GIRKVITESTVHLIQLLENYKKKLQEF 335 +T D TF + K L IR+ + ++ I + + Sbjct: 354 NLNDTFD-TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVV 412 Query: 336 SKEEEYDIRTQVSAVV----------------QRKYWTSKPEPSTREQFLQYAYD----- 374 S E +Y I T + VV Q Y + T+ F+ A + Sbjct: 413 SYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSR 472 Query: 375 -------------ITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQ 421 DP +AH+ L++ +N V P RF Sbjct: 473 SSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES-SSKKSHTPERFTSQGSYGVA 531 Query: 422 QSLYLH--RYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAW 479 ++++ R+Y+EV I G+ Y G+ K ++ I N+ SW+L + Sbjct: 532 GNVFIDSGRHYWEVVISGSTWYA----IGLAYKSAPKHEWIGKNSASWALCRCNNNWVVR 587 Query: 480 YSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVH--KFACKFSEPVYAAFWL 536 ++ E P++ P RR+G+ +D+ G ++F YD + +H F F++PV F + Sbjct: 588 HNSKEIPIEPAPHLRRVGILLDYDNGSIAF----YDALNSIHLYTFDVAFAQPVCPTFTV 643 Query: 537 SKK 539 K Sbjct: 644 WNK 646 >gi|223890259 midline 2 isoform 2 [Homo sapiens] Length = 705 Score = 84.0 bits (206), Expect = 3e-16 Identities = 125/550 (22%), Positives = 214/550 (38%), Gaps = 93/550 (16%) Query: 69 AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIK-LQSHLLTEPVKDHN 127 A + + C FC D R AVK+C+TC V+YC+ L+ N K SH L EPV D + Sbjct: 131 AMSSERIACQFCEQDPPR-DAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTH 189 Query: 128 WR--YCPAH-HSPLSAFCCPDQQCICQDC--CQEHSGHTIVSL----------------D 166 R C H + ++ +C D Q IC C H H + SL + Sbjct: 190 LRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249 Query: 167 AARRDKEAELQ-------CTQLDLE---RKLKLNENA---ISRLQANQKSVLVSVSEVKA 213 +R+ E E Q C Q+++ + KL E + +Q ++ + V + E K Sbjct: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309 Query: 214 VAEMQFGELLAAVRKA--QANVML-----FLEEKEQAA-LSQANGIKAHLEYRSAEMEKS 265 + + + +A R+ ++ V++ L+E +QA L A I + +A + Sbjct: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVL 369 Query: 266 KQELERMAAISN-TVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQ- 323 ++ A N + F E + + +T P+ ++ + I TVH I Sbjct: 370 IPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI---TVHWISD 426 Query: 324 ---LLENYKKKLQEFSKEEEY-------DIRTQVSAVVQRKYWTSKPEPSTREQFLQYAY 373 + +Y+ + F+ + + D V + Q Y + TR F+ A Sbjct: 427 DEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAI 486 Query: 374 D------------------ITFDPDTAHKYLRLQEEN---RKVTNTTPWEHPYPDLPSRF 412 + DP HK L++ + K ++ H P RF Sbjct: 487 NQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSH----TPERF 542 Query: 413 LHWRQVLSQQSLYLHR--YYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQ 470 + ++++ +Y+EV + G+ T+ + GI K +N I N SW Sbjct: 543 SGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAI---GIAYKSAPKNEWIGKNASSWVFS 598 Query: 471 WNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEP 529 F +++ E + P +RLGV +D+ +LSFY + +H F F P Sbjct: 599 RCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFY--DPANSLHLHTFDVTFILP 656 Query: 530 VYAAFWLSKK 539 V F + K Sbjct: 657 VCPTFTIWNK 666 >gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sapiens] Length = 474 Score = 77.0 bits (188), Expect = 4e-14 Identities = 104/431 (24%), Positives = 166/431 (38%), Gaps = 81/431 (18%) Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLK 188 C H PL FC DQ+ +C C QEH H + +D A +L +Q +L K+K Sbjct: 87 CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMK 146 Query: 189 LNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQA 248 ++ Q + + ++ K + Q + K FL E+E L + Sbjct: 147 -------KVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHN----FLVEEEDLFLQRL 195 Query: 249 NGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLS 308 N E E++K++L NT++ L ++ Sbjct: 196 N----------KEEEETKKKLNE-----NTLK----------------------LNQTIA 218 Query: 309 GIRKVITE----STVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST 364 ++K+I E S ++LL+N K+ L ++ E D+ + AV K T P Sbjct: 219 SLKKLILEVGEKSQAPTLELLQNPKEVL---TRSEIQDVNYSLEAV---KVKTVCQIPLM 272 Query: 365 REQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTP----------------WEHPYPD- 407 +E ++ + DTAH L +E R V NT W +P Sbjct: 273 KEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTA 332 Query: 408 LPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSW 467 RF H VL + ++Y+EVE + C+ D G S +S + W Sbjct: 333 FVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCRE-DVMGITDRSKMSPDVGIW 391 Query: 468 SLQWNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKF 526 ++ W+ + TP + P R+GVY+D G +SFY D + L H F+C Sbjct: 392 AIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSA-VDGVHL-HTFSCSS 449 Query: 527 SEPVYAAFWLS 537 + FWLS Sbjct: 450 VSRLRPFFWLS 460 >gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] Length = 526 Score = 75.9 bits (185), Expect = 9e-14 Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%) Query: 371 YAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYY 430 +A D+T DPDTAH +L L E+++ V P+ RF W VL +++ R+Y Sbjct: 301 HAVDVTLDPDTAHPHLFLYEDSKSV-RLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHY 359 Query: 431 FEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK- 488 +EVE+ + +G+ + + +KG + ++ N W+++ G + A + + TPL Sbjct: 360 WEVEVGDRTDWAIGVCRENVMKKGFDP---MTPENGFWAVELYGNGYWA-LTPLRTPLPL 415 Query: 489 AGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL-SKKENAIRIVD 547 AGP RR+G+++D+ G +SFY + D + FS P+ F L S + + I Sbjct: 416 AGPPRRVGIFLDYESGDISFYNMN-DGSDIYTFSNVTFSGPLRPFFCLWSSGKKPLTICP 474 Query: 548 LGEEPEK 554 + + PE+ Sbjct: 475 IADGPER 481 >gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor [Homo sapiens] Length = 527 Score = 75.9 bits (185), Expect = 9e-14 Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 37/254 (14%) Query: 305 DKLSGIRKVIT-----ESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSK 359 +KL +K+++ E I L E K+++Q KEEE ++ ++ ++ W Sbjct: 270 NKLQKEKKILSGEKEFERETREIALKELEKERVQ---KEEELQVKEKLQEELR---W--- 320 Query: 360 PEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEH---PYPDLPSRFLHWR 416 R FL +A D+ DPDTAH L L E+ R V P+ H PD P RF Sbjct: 321 -----RRTFL-HAVDVVLDPDTAHPDLFLSEDRRSV-RRCPFRHLGESVPDNPERFDSQP 373 Query: 417 QVLSQQSLYLHRYYFEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKE 475 VL ++S ++Y+EVE+ + VG+ ++RKGE I N F W+L+ + + Sbjct: 374 CVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEV--LLIPQNGF-WTLEMHKGQ 430 Query: 476 FTAWYS-DMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVY 531 + A S D PLK R+GV++D+ G +SFY + + H + C FS PV Sbjct: 431 YRAVSSPDRILPLKES-LCRVGVFLDYEAGDVSFYNMRDRS----HIYTCPRSAFSVPVR 485 Query: 532 AAFWLSKKENAIRI 545 F L +++ I I Sbjct: 486 PFFRLGCEDSPIFI 499 >gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo sapiens] Length = 500 Score = 75.5 bits (184), Expect = 1e-13 Identities = 100/436 (22%), Positives = 167/436 (38%), Gaps = 65/436 (14%) Query: 131 CPAHHSPLSAFCCPDQQCICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLD-----L 183 C H PL FC DQ+ +C C QEH H + +D A +D L Sbjct: 87 CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRL 146 Query: 184 ERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQA 243 R L + +L +Q++++ + +V + +++ K ++ M E + Sbjct: 147 IRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL 206 Query: 244 ALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGL 303 L+ + E E++K++L NT++ L Sbjct: 207 HNFLVEEEDLFLQRLNKEEEETKKKLN-----ENTLK----------------------L 239 Query: 304 KDKLSGIRKVITE----STVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSK 359 ++ ++K+I E S ++LL+N K+ L ++ E D+ + AV K T Sbjct: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVL---TRSEIQDVNYSLEAV---KVKTVC 293 Query: 360 PEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTP----------------WEH 403 P +E ++ + DTAH L +E R V NT W + Sbjct: 294 QIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 353 Query: 404 PYPD-LPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISG 462 P RF H VL + ++Y+EVE + C+ D G S +S Sbjct: 354 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCRE-DVMGITDRSKMSP 412 Query: 463 NNFSWSLQWNGKEFTAWYSDMETPLKAGP-FRRLGVYIDFPGGILSFYGVEYDTMTLVHK 521 + W++ W+ + TP + P R+GVY+D G +SFY D + L H Sbjct: 413 DVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSA-VDGVHL-HT 470 Query: 522 FACKFSEPVYAAFWLS 537 F+C + FWLS Sbjct: 471 FSCSSVSRLRPFFWLS 486 >gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo sapiens] Length = 407 Score = 75.1 bits (183), Expect = 2e-13 Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 28/231 (12%) Query: 322 IQLLENYKKKLQEFSK--EEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDP 379 I+ L+ KK L K +EE +I Q+ ++ W R FL +A D+ DP Sbjct: 170 IKKLQREKKILSGEKKVEQEEKEIAQQLQEELR---W--------RRTFL-HAADVVLDP 217 Query: 380 DTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAG 439 DTAH L L E+ R V P+ PD P RF VL +S ++Y+EVE+ Sbjct: 218 DTAHPELFLSEDRRSV-RRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVM 276 Query: 440 TY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYS-DMETPLKAGPFRRLGV 497 + VG+ ++RKGE I N F W+L+ G ++ A S + PLK R+GV Sbjct: 277 VWTVGVCRHSVERKGEV--LLIPQNGF-WTLEMFGNQYRALSSPERILPLKES-LCRVGV 332 Query: 498 YIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVYAAFWLSKKENAIRI 545 ++D+ G +SFY + + H + C F+ PV F L ++ I I Sbjct: 333 FLDYEAGDVSFYNMRDRS----HIYTCPRSAFTVPVRPFFRLGSDDSPIFI 379 >gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo sapiens] Length = 523 Score = 75.1 bits (183), Expect = 2e-13 Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 28/231 (12%) Query: 322 IQLLENYKKKLQEFSK--EEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDP 379 I+ L+ KK L K +EE +I Q+ ++ W R FL +A D+ DP Sbjct: 286 IKKLQREKKILSGEKKVEQEEKEIAQQLQEELR---W--------RRTFL-HAADVVLDP 333 Query: 380 DTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAG 439 DTAH L L E+ R V P+ PD P RF VL +S ++Y+EVE+ Sbjct: 334 DTAHPELFLSEDRRSV-RRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVM 392 Query: 440 TY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYS-DMETPLKAGPFRRLGV 497 + VG+ ++RKGE I N F W+L+ G ++ A S + PLK R+GV Sbjct: 393 VWTVGVCRHSVERKGEV--LLIPQNGF-WTLEMFGNQYRALSSPERILPLKES-LCRVGV 448 Query: 498 YIDFPGGILSFYGVEYDTMTLVHKFAC---KFSEPVYAAFWLSKKENAIRI 545 ++D+ G +SFY + + H + C F+ PV F L ++ I I Sbjct: 449 FLDYEAGDVSFYNMRDRS----HIYTCPRSAFTVPVRPFFRLGSDDSPIFI 495 >gi|4557743 Mediterranean fever protein [Homo sapiens] Length = 781 Score = 74.7 bits (182), Expect = 2e-13 Identities = 118/537 (21%), Positives = 213/537 (39%), Gaps = 93/537 (17%) Query: 30 PSPDSGSASPVEEEDVGSSEKL-GR--ETEEQDSDSAEQGDP------------------ 68 P+PD G+++ ++E + GR +T A++GDP Sbjct: 281 PTPDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSG 340 Query: 69 ---AGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKD 125 A + C C D R K+ S + C+ HL+ Q+ Sbjct: 341 HPQASGSRSPGCPRCQDSHER-KSPGSLSPQPLPQCKRHLKQVQL--------------- 384 Query: 126 HNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLER 185 +C H P+ C QEH GH + ++ + + ++Q LE Sbjct: 385 ---LFCEDHDEPICLIC---------SLSQEHQGHRVRPIEEVALEHKKKIQ---KQLEH 429 Query: 186 KLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAA-VRKAQANVMLFLEEKEQAA 244 KL ++ + S E KAV+ ++ E L V++ V FLE++E Sbjct: 430 LKKLRKSGEEQR---------SYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFF 480 Query: 245 LSQANGIKAHL-EYRSAEMEKSKQELERMAAISNTVQFLE---EYCKFKNTEDITFPSVY 300 ++ + + + R A + Q++ + A+ ++ E E+ ++ DI + Sbjct: 481 VASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKT 540 Query: 301 VGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKP 360 V + +K + +++ + IQLL + +++ +K +R+++ + P Sbjct: 541 VPVPEKWTTPQEIKQK-----IQLLHQKSEFVEKSTKYFSETLRSEMEMF-------NVP 588 Query: 361 EPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLS 420 E + +A ++ D +TA+ L ++ + V WE PD P RF VL Sbjct: 589 ELIGAQA---HAVNVILDAETAYPNLIFSDDLKSVRLGNKWER-LPDGPQRFDSCIIVLG 644 Query: 421 QQSLYLHRYYFEVEIFGAGTYVGLTCK-GIDRKGEERNSCISGNNFSWS-LQWNGKEFTA 478 S R Y+EVE+ ++ CK I RKG N +S N W + E+ A Sbjct: 645 SPSFLSGRRYWEVEVGDKTAWILGACKTSISRKG---NMTLSPENGYWVVIMMKENEYQA 701 Query: 479 WYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534 L P +R+G+++D+ G +SFY V + ++ FA C FS P+ F Sbjct: 702 SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNV--TARSHIYTFASCSFSGPLQPIF 756 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 74.3 bits (181), Expect = 3e-13 Identities = 101/472 (21%), Positives = 187/472 (39%), Gaps = 83/472 (17%) Query: 92 SCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWR---YCPAHHSPLSAFCCPDQQC 148 SC C ++Y EHLQ +Q + L + N + C H L FC D++ Sbjct: 55 SCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKV 114 Query: 149 ICQDC--CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLV 206 IC C QEH GH V + ++ + +LQ L+++ + E + ++ + S Sbjct: 115 ICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKY 174 Query: 207 SVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSK 266 V + + +F +L + + + + LEE+E+ L ++ AE E + Sbjct: 175 QVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLD---------KFAEAEDELVQ 225 Query: 267 QELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLE 326 Q+ + + + + V+ ++ + +D +SGI K S + ++ + Sbjct: 226 QK-QLVRELISDVECRSQWSTMELLQD-------------MSGIMK---WSEIWRLKKPK 268 Query: 327 NYKKKLQEFSKEEEYDIRTQV--SAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHK 384 KKL+ + Q+ R YW D+T + + Sbjct: 269 MVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWV----------------DVTLNSVNLNL 312 Query: 385 YLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYV-G 443 L L E+ R+V + W P + ++ VL Q ++Y+EV++ ++ G Sbjct: 313 NLVLSEDQRQVISVPIW-------PFQCYNY-GVLGSQYFSSGKHYWEVDVSKKTAWILG 364 Query: 444 LTCKGIDRKGE-ERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFR--------- 493 + C+ R + C + N + F W ++ K G F Sbjct: 365 VYCRTYSRHMKYVVRRCANRQNLYTKYR---PLFGYWVIGLQNKCKYGVFEESLSSDPEV 421 Query: 494 ----------RLGVYIDFPGGILSFYGVEYDTMTLVHKFA-CKFSEPVYAAF 534 R+GV++D+ GI+SF+ V +L++KF+ C FS+PVY F Sbjct: 422 LTLSMAVPPCRVGVFLDYEAGIVSFFNVT-SHGSLIYKFSKCCFSQPVYPYF 472 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,521,729 Number of Sequences: 37866 Number of extensions: 1188821 Number of successful extensions: 10115 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 128 Number of HSP's successfully gapped in prelim test: 290 Number of HSP's that attempted gapping in prelim test: 9156 Number of HSP's gapped (non-prelim): 1046 length of query: 564 length of database: 18,247,518 effective HSP length: 108 effective length of query: 456 effective length of database: 14,157,990 effective search space: 6456043440 effective search space used: 6456043440 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.