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Search of human proteins with 48255907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255907 transgelin [Homo sapiens]
(201 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255907 transgelin [Homo sapiens] 409 e-115
gi|48255905 transgelin [Homo sapiens] 409 e-115
gi|56549135 transgelin 3 [Homo sapiens] 282 2e-76
gi|56549139 transgelin 3 [Homo sapiens] 282 2e-76
gi|56549137 transgelin 3 [Homo sapiens] 282 2e-76
gi|4507357 transgelin 2 [Homo sapiens] 273 5e-74
gi|4502923 calponin 3 [Homo sapiens] 147 5e-36
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 139 2e-33
gi|4758018 calponin 2 isoform a [Homo sapiens] 125 2e-29
gi|41327730 calponin 2 isoform b [Homo sapiens] 102 3e-22
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 47 8e-06
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 42 3e-04
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 41 6e-04
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 41 6e-04
gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 40 0.001
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 36 0.019
gi|30181233 leucine-rich repeats and calponin homology (CH) doma... 36 0.019
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 36 0.025
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 34 0.073
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 34 0.073
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 34 0.073
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 34 0.073
gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 33 0.12
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 31 0.81
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 29 2.4
gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regula... 29 3.1
gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regula... 29 3.1
gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regula... 29 3.1
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 29 3.1
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 29 3.1
>gi|48255907 transgelin [Homo sapiens]
Length = 201
Score = 409 bits (1051), Expect = e-115
Identities = 201/201 (100%), Positives = 201/201 (100%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
Query: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120
ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
Sbjct: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120
Query: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180
KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
Sbjct: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180
Query: 181 SNRGASQAGMTGYGRPRQIIS 201
SNRGASQAGMTGYGRPRQIIS
Sbjct: 181 SNRGASQAGMTGYGRPRQIIS 201
>gi|48255905 transgelin [Homo sapiens]
Length = 201
Score = 409 bits (1051), Expect = e-115
Identities = 201/201 (100%), Positives = 201/201 (100%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
Sbjct: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
Query: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120
ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
Sbjct: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120
Query: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180
KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
Sbjct: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180
Query: 181 SNRGASQAGMTGYGRPRQIIS 201
SNRGASQAGMTGYGRPRQIIS
Sbjct: 181 SNRGASQAGMTGYGRPRQIIS 201
>gi|56549135 transgelin 3 [Homo sapiens]
Length = 199
Score = 282 bits (721), Expect = 2e-76
Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119
+L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E
Sbjct: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118
Query: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179
GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM
Sbjct: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178
Query: 180 GSNRGASQAGMTGYGRPRQII 200
GSN+GASQAGMTGYG PRQI+
Sbjct: 179 GSNKGASQAGMTGYGMPRQIM 199
>gi|56549139 transgelin 3 [Homo sapiens]
Length = 199
Score = 282 bits (721), Expect = 2e-76
Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119
+L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E
Sbjct: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118
Query: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179
GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM
Sbjct: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178
Query: 180 GSNRGASQAGMTGYGRPRQII 200
GSN+GASQAGMTGYG PRQI+
Sbjct: 179 GSNKGASQAGMTGYGMPRQIM 199
>gi|56549137 transgelin 3 [Homo sapiens]
Length = 199
Score = 282 bits (721), Expect = 2e-76
Identities = 136/201 (67%), Positives = 170/201 (84%), Gaps = 3/201 (1%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MAN+GPSYG+SREVQ KIE+KYD +LE +LV+WII+QC D+ P GR FQ WL +G
Sbjct: 1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT 60
Query: 61 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE 119
+L KL+NSLYP G +P+ K+ E+ M FKQMEQ++QFLKAAE YGV TD+FQTVDL+E
Sbjct: 61 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE 118
Query: 120 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM 179
GKDMAAVQRTLMALGS+AVTK+DG YRG+P+WF +KAQ+++R F+E QL++G++VIGLQM
Sbjct: 119 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM 178
Query: 180 GSNRGASQAGMTGYGRPRQII 200
GSN+GASQAGMTGYG PRQI+
Sbjct: 179 GSNKGASQAGMTGYGMPRQIM 199
>gi|4507357 transgelin 2 [Homo sapiens]
Length = 199
Score = 273 bits (699), Expect = 5e-74
Identities = 130/200 (65%), Positives = 165/200 (82%), Gaps = 1/200 (0%)
Query: 1 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV 60
MAN+GP+YG+SREVQ KIEK+YD +LE+ L++WI QC DVGRP GR FQ WLK+G
Sbjct: 1 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT 60
Query: 61 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG 120
+L +L+N+LYP+G PVK + +M FKQMEQ++QFL+AAE YG+ TD+FQTVDL+EG
Sbjct: 61 VLCELINALYPEGQAPVKKIQ-ASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG 119
Query: 121 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG 180
K+MA VQRTLM LG LAV ++DG + GDPNWF KK++E+ R F+++QLQEGK+VIGLQMG
Sbjct: 120 KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG 179
Query: 181 SNRGASQAGMTGYGRPRQII 200
+NRGASQAGMTGYG PRQI+
Sbjct: 180 TNRGASQAGMTGYGMPRQIL 199
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 147 bits (372), Expect = 5e-36
Identities = 86/197 (43%), Positives = 118/197 (59%), Gaps = 13/197 (6%)
Query: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
NKGPSYG+S EV++KI KYD + EE L WI G +G FQ+ LK+G+IL
Sbjct: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGP------NFQLGLKDGIIL 58
Query: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
+L+N L P K V N S+ + Q+E + F+KA + YG+ D+F+ DLFE +
Sbjct: 59 CELINKLQPGSVKKV----NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGN 114
Query: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
M VQ TL+AL LA TK + + +K A++ R F E +L+ G+ VIGLQMG+N
Sbjct: 115 MTQVQTTLVALAGLAKTKG---FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTN 171
Query: 183 RGASQAGMTGYGRPRQI 199
+ ASQAGMT YG R +
Sbjct: 172 KCASQAGMTAYGTRRHL 188
Score = 32.7 bits (73), Expect = 0.21
Identities = 15/25 (60%), Positives = 19/25 (76%)
Query: 175 IGLQMGSNRGASQAGMTGYGRPRQI 199
I LQMG+N+ ASQ GM+ YG RQ+
Sbjct: 243 ISLQMGTNKVASQKGMSVYGLGRQV 267
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 139 bits (350), Expect = 2e-33
Identities = 78/197 (39%), Positives = 117/197 (59%), Gaps = 15/197 (7%)
Query: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
N+GP+YG+S EV++K+ +KYD + E+ L EWI G +G F LK+G+IL
Sbjct: 7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGN------NFMDGLKDGIIL 60
Query: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
+ +N L P K + N + + Q+E + F+KA YGV D+F+ DLFE +
Sbjct: 61 CEFINKLQPGSVKKI----NESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTN 116
Query: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
VQ TL+AL S+A TK + N +K A++ +R+F +L+EG+++IGLQMG+N
Sbjct: 117 HTQVQSTLLALASMAKTKGN-----KVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTN 171
Query: 183 RGASQAGMTGYGRPRQI 199
+ ASQ GMT YG R +
Sbjct: 172 KFASQQGMTAYGTRRHL 188
Score = 42.0 bits (97), Expect = 4e-04
Identities = 18/25 (72%), Positives = 21/25 (84%)
Query: 175 IGLQMGSNRGASQAGMTGYGRPRQI 199
+ LQMGSN+GASQ GMT YG PRQ+
Sbjct: 243 VSLQMGSNKGASQRGMTVYGLPRQV 267
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 125 bits (315), Expect = 2e-29
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 13/197 (6%)
Query: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
NKGPSYG+S EV++++ KYD + E L WI G +G PD FQ LK+G IL
Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG-PD-----FQKGLKDGTIL 60
Query: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
L+N L P GS P K+ N + Q+E ++ F+KA YG+ D+F+ DLFE +
Sbjct: 61 CTLMNKLQP-GSVP-KI--NRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGN 116
Query: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
M VQ +L+AL A TK + + +K +++ +R F ++ ++ G+ VIGLQMG+N
Sbjct: 117 MTQVQVSLLALAGKAKTKG---LQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTN 173
Query: 183 RGASQAGMTGYGRPRQI 199
+ ASQ+GMT YG R +
Sbjct: 174 KCASQSGMTAYGTRRHL 190
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 102 bits (253), Expect = 3e-22
Identities = 76/198 (38%), Positives = 103/198 (52%), Gaps = 14/198 (7%)
Query: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
NKGPSYG+S EV++++ KYD + E L WI G +G PD FQ LK+G IL
Sbjct: 7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIG-PD-----FQKGLKDGTIL 60
Query: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
L+N L P GS P K+ N + Q+E ++ F+KA YG+ D+F+ DLFE +
Sbjct: 61 CTLMNKLQP-GSVP-KI--NRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGN 116
Query: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKH-VIGLQMGS 181
M VQ +L+AL T G + ++ H + L H I LQMG+
Sbjct: 117 MTQVQVSLLALAGKMGTNKCASQSGMTAYGTRR---HLYDPKNHILPPMDHSTISLQMGT 173
Query: 182 NRGASQAGMTGYGRPRQI 199
N+ ASQ GMT G R I
Sbjct: 174 NKCASQVGMTAPGTRRHI 191
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 47.4 bits (111), Expect = 8e-06
Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLK-AAEDYGVIKTDMFQT 114
L++GV+L +L+N+L P +V P F ++ + FL E +G+ ++++F+
Sbjct: 37 LRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEA 96
Query: 115 VDLFEGKDMAAVQRTLMALGSLAVTKNDG 143
DLF+ +D V TL AL + +N G
Sbjct: 97 FDLFDVQDFGKVIYTLSALSWTPIAQNRG 125
>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 847
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKA-AEDYGVIKTDMFQT 114
L++GV+L +L+N+L ++ P F ++ + FL A E +G+ K+++F+
Sbjct: 37 LRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEA 96
Query: 115 VDLFEGKDMAAVQRTLMALGSLAVTKNDG 143
DLF+ +D V TL L + G
Sbjct: 97 FDLFDVRDFGKVIETLSRLSRTPIALATG 125
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 41.2 bits (95), Expect = 6e-04
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAED-YGVIKTDMFQT 114
L++GV+L +L+++L P + P F ++ + FLK D +G+ +++F
Sbjct: 37 LRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDP 96
Query: 115 VDLFEGKDMAAVQRTLMALGSLAVTKNDG 143
DLF+ +D V + L ++ +N G
Sbjct: 97 FDLFDVRDFGKVISAVSRLSLHSIAQNKG 125
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 41.2 bits (95), Expect = 6e-04
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAED-YGVIKTDMFQT 114
L++GV+L +L+++L P + P F ++ + FLK D +G+ +++F
Sbjct: 37 LRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDP 96
Query: 115 VDLFEGKDMAAVQRTLMALGSLAVTKNDG 143
DLF+ +D V + L ++ +N G
Sbjct: 97 FDLFDVRDFGKVISAVSRLSLHSIAQNKG 125
>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
containing 1 [Homo sapiens]
Length = 728
Score = 40.0 bits (92), Expect = 0.001
Identities = 38/138 (27%), Positives = 62/138 (44%), Gaps = 17/138 (12%)
Query: 6 PSYGMSREV-QSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSK 64
P + + R++ Q + EK+ E+L E + + V D+G L +GV+L
Sbjct: 565 PQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAA----------LMDGVVLCH 614
Query: 65 LVNSLYPDGSKPVKVPEN--PPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
LVN + P + VP P + K V FL+A GV + D+ D+ + D
Sbjct: 615 LVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQ-LD 673
Query: 123 MAAVQR---TLMALGSLA 137
+++ TL+ALG A
Sbjct: 674 FRHIRKTVDTLLALGEKA 691
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 36.2 bits (82), Expect = 0.019
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Query: 52 FQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDM 111
F+ L+NGV+L L+N L P K + N S ++ + FLKA E G+ + +
Sbjct: 87 FRASLENGVLLCDLINKLKPGVIKKI----NRLSTPIAGLDNINVFLKACEQIGLKEAQL 142
Query: 112 FQTVDLFEGKDMAAVQR 128
F DL + + V++
Sbjct: 143 FHPGDLQDLSNRVTVKQ 159
>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
containing 4 [Homo sapiens]
Length = 683
Score = 36.2 bits (82), Expect = 0.019
Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPEN--PPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQ 113
L +GVIL +L N L P + VP P K + V FL+A GV + D+
Sbjct: 564 LASGVILCQLANQLRPRSVPFIHVPSPAVPKLSALKARKNVESFLEACRKMGVPEADLCS 623
Query: 114 TVDLFEG 120
DL +G
Sbjct: 624 PSDLLQG 630
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 35.8 bits (81), Expect = 0.025
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTV 115
LKNGV+L KL+N L P + + P + + FLK ++ ++F
Sbjct: 35 LKNGVVLCKLINRLMPGSVEKFCL---DPQTEADCINNINDFLKGC---ATLQVEIFDPD 88
Query: 116 DLFEGKDMAAVQRTLMAL 133
DL+ G + + V TL+A+
Sbjct: 89 DLYSGVNFSKVLSTLLAV 106
>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
containing 2 [Homo sapiens]
Length = 765
Score = 34.3 bits (77), Expect = 0.073
Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 6 PSYGMSREVQS-KIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSK 64
P + M R+++ + E++ +L L + V D+G L +GV+L
Sbjct: 631 PGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAA----------LMDGVVLCH 680
Query: 65 LVNSLYPDGSKPVKVPEN--PPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
L N + P + VP P + K V FL A + GV + + + E +
Sbjct: 681 LANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVSQERLCLPHHILEERG 740
Query: 123 MAAVQRTLMALGSLAVTK 140
+ V T+ AL L TK
Sbjct: 741 LVKVGVTVQALLELPTTK 758
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 34.3 bits (77), Expect = 0.073
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 32 EWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQM 91
+WI G G D F+ L+NG++L +L+N++ P K + P +
Sbjct: 29 KWIEQVTGRSFGDKD-----FRTGLENGILLCELLNAIKPGLVKKINRLPTP----IAGL 79
Query: 92 EQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQ 127
+ + FL+ ++ G+ ++ +F DL + + V+
Sbjct: 80 DNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 34.3 bits (77), Expect = 0.073
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 32 EWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQM 91
+WI G G D F+ L+NG++L +L+N++ P K + P +
Sbjct: 29 KWIEQVTGRSFGDKD-----FRTGLENGILLCELLNAIKPGLVKKINRLPTP----IAGL 79
Query: 92 EQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQ 127
+ + FL+ ++ G+ ++ +F DL + + V+
Sbjct: 80 DNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 34.3 bits (77), Expect = 0.073
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 32 EWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQM 91
+WI G G D F+ L+NG++L +L+N++ P K + P +
Sbjct: 29 KWIEQVTGRSFGDKD-----FRTGLENGILLCELLNAIKPGLVKKINRLPTP----IAGL 79
Query: 92 EQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQ 127
+ + FL+ ++ G+ ++ +F DL + + V+
Sbjct: 80 DNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVK 115
>gi|4506787 IQ motif containing GTPase activating protein 1 [Homo
sapiens]
Length = 1657
Score = 33.5 bits (75), Expect = 0.12
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 6/74 (8%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPENPPS------MVFKQMEQVAQFLKAAEDYGVIKT 109
L+NGV L+KL N P K+ + + + F+ + V Q+L A ++ G+ K
Sbjct: 72 LRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKI 131
Query: 110 DMFQTVDLFEGKDM 123
+T D+++ K+M
Sbjct: 132 FYPETTDIYDRKNM 145
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 30.8 bits (68), Expect = 0.81
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 53 QVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMF 112
Q LK+GV+L +L+ L P G+ PE P + + + +FL+ ++ + F
Sbjct: 32 QASLKDGVVLCRLLERLLP-GTIEKVYPE--PRSESECLSNIREFLRGCG--ASLRLETF 86
Query: 113 QTVDLFEGKDMAAVQRTLMALGSL 136
DL++G++ V +L+ L +
Sbjct: 87 DANDLYQGQNFNKVLSSLVTLNKV 110
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 29.3 bits (64), Expect = 2.4
Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 56 LKNGVILSKLVNSLYPDGSKPVKVPE------NPPSMVFKQMEQVAQFLKAAEDYGVIKT 109
L+NGV+L+KL + P K+ + + F+ + + +L A G+ T
Sbjct: 62 LRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPST 121
Query: 110 DMFQTVDLFEGKDMAAVQRTLMAL 133
+T D+++ K+M V + AL
Sbjct: 122 FFPETTDIYDKKNMPRVVYCIHAL 145
>gi|18765756 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 5 [Homo sapiens]
Length = 529
Score = 28.9 bits (63), Expect = 3.1
Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 148 DPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGY 193
D W +KK ++ KRE+ ++ +++G++ G G +AG +G+
Sbjct: 400 DGTWNLKKTKDGKREYKPPGTRKLHNILGVETG-GPGGRRAGESGH 444
>gi|18765754 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 4 [Homo sapiens]
Length = 540
Score = 28.9 bits (63), Expect = 3.1
Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 148 DPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGY 193
D W +KK ++ KRE+ ++ +++G++ G G +AG +G+
Sbjct: 400 DGTWNLKKTKDGKREYKPPGTRKLHNILGVETG-GPGGRRAGESGH 444
>gi|18765750 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 3 [Homo sapiens]
Length = 584
Score = 28.9 bits (63), Expect = 3.1
Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 148 DPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGY 193
D W +KK ++ KRE+ ++ +++G++ G G +AG +G+
Sbjct: 400 DGTWNLKKTKDGKREYKPPGTRKLHNILGVETG-GPGGRRAGESGH 444
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 28.9 bits (63), Expect = 3.1
Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 148 DPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGY 193
D W +KK ++ KRE+ ++ +++G++ G G +AG +G+
Sbjct: 391 DGTWNLKKTKDGKREYKPPGTRKLHNILGVETG-GPGGRRAGESGH 435
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 28.9 bits (63), Expect = 3.1
Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 148 DPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGY 193
D W +KK ++ KRE+ ++ +++G++ G G +AG +G+
Sbjct: 400 DGTWNLKKTKDGKREYKPPGTRKLHNILGVETG-GPGGRRAGESGH 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,641,752
Number of Sequences: 37866
Number of extensions: 316257
Number of successful extensions: 925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 888
Number of HSP's gapped (non-prelim): 40
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.