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Search of human proteins with 47933392
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47933392 cytohesin 1 interacting protein [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47933392 cytohesin 1 interacting protein [Homo sapiens] 714 0.0
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso... 186 2e-47
gi|21361142 PDZ domain containing 1 [Homo sapiens] 58 1e-08
gi|148727255 microtubule associated serine/threonine kinase fami... 55 1e-07
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 55 1e-07
gi|45120119 microtubule associated serine/threonine kinase 1 [Ho... 51 1e-06
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 50 3e-06
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 50 3e-06
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 49 9e-06
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 49 9e-06
gi|112363080 microtubule associated serine/threonine kinase 2 [H... 48 2e-05
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 48 2e-05
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 48 2e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 47 3e-05
gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2 ... 46 6e-05
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 46 6e-05
gi|148746189 multiple PDZ domain protein [Homo sapiens] 44 2e-04
gi|169217736 PREDICTED: similar to PDZ domain containing 1 [Homo... 44 2e-04
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 43 4e-04
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 43 5e-04
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor... 43 5e-04
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 43 5e-04
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 43 5e-04
gi|9507165 syntrophin, gamma 2 [Homo sapiens] 42 9e-04
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 41 0.001
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s... 41 0.001
gi|45827729 scribble isoform b [Homo sapiens] 41 0.001
gi|45827731 scribble isoform a [Homo sapiens] 41 0.001
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 41 0.001
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 41 0.001
>gi|47933392 cytohesin 1 interacting protein [Homo sapiens]
Length = 359
Score = 714 bits (1842), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLA 60
MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLA
Sbjct: 1 MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLA 60
Query: 61 LTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA 120
LTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA
Sbjct: 61 LTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA 120
Query: 121 HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV 180
HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV
Sbjct: 121 HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV 180
Query: 181 LKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRL 240
LKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRL
Sbjct: 181 LKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRL 240
Query: 241 SSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSR 300
SSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSR
Sbjct: 241 SSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSR 300
Query: 301 RNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF 359
RNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF
Sbjct: 301 RNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF 359
>gi|32171221 GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein [Homo sapiens]
Length = 395
Score = 186 bits (473), Expect = 2e-47
Identities = 129/333 (38%), Positives = 186/333 (55%), Gaps = 28/333 (8%)
Query: 45 LADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACS 104
LA + TLPR RK R +LS QRK++T+EK+DN+TFGFEIQ+Y ++
Sbjct: 71 LAVSGGTLPR-RKGSGF-RWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQR 128
Query: 105 SEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLN 164
EM T +C++ E SPA AGL GD +A++NG++ EG ++++VD+I++SGN+L +ETL
Sbjct: 129 VEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLY 188
Query: 165 GTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSL-ENMDLDELSL 223
GT I ++ ELEA+LQ LKQTL +KW EYRSL +QE RL+HG PS+ + ++ L
Sbjct: 189 GTSI-RKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCL 247
Query: 224 FGP--LPGP---GPALVDRNRLSSESSCKSWLSSMTMDSEDG-YQTCVSEDSSRGAF--- 274
+G LPG GP L R + D++D Y TC DS A
Sbjct: 248 YGAGLLPGSLPFGPLLAVPGR------PRGGARRARGDADDAVYHTCFFGDSEPPALPPP 301
Query: 275 --SRQTSTDDECFIPKEGDDFLRRSSSRRNRSI------SNTSSGSMSPLW-EGNLSSMF 325
+ P G R++ R+ S+ G+ LW E ++
Sbjct: 302 PPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEAREQALC 361
Query: 326 GTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESR 358
G RK++ S R++LLKFIPGL+R++EEEES+
Sbjct: 362 GPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQ 394
>gi|21361142 PDZ domain containing 1 [Homo sapiens]
Length = 519
Score = 58.2 bits (139), Expect = 1e-08
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 8/109 (7%)
Query: 80 VEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVST 139
+ KQ+ + +GF ++ + + L+ +++ SPA AGLQ GD + INGV
Sbjct: 12 LSKQEGQNYGFFLRIEKDTEGH--------LVRVVEKCSPAEKAGLQDGDRVLRINGVFV 63
Query: 140 EGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQK 188
+ + QVVDL+R SGN +T+ L+G K + L+ L Q+ K++
Sbjct: 64 DKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQ 112
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 9/85 (10%)
Query: 76 KLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANIN 135
KL + K +N +GF + NA + I ++Q+ PA AGL+ DV+ +N
Sbjct: 377 KLCRLAKGENG-YGFHL--------NAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVN 427
Query: 136 GVSTEGFTYKQVVDLIRSSGNLLTI 160
GV+ Y++VVD I+SSG +T+
Sbjct: 428 GVNVLDEPYEKVVDRIQSSGKNVTL 452
Score = 39.7 bits (91), Expect = 0.004
Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 9/132 (6%)
Query: 25 SSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQD 84
+S+ + + +R + +L D +++ R ++ Q ++V ++K
Sbjct: 191 ASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGS 250
Query: 85 NETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTY 144
N +GF ++ A S + +I I SPA AGL+ D++ +NG S E +
Sbjct: 251 NG-YGFYLR--------AGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDH 301
Query: 145 KQVVDLIRSSGN 156
VV++IR G+
Sbjct: 302 DSVVEMIRKGGD 313
Score = 34.3 bits (77), Expect = 0.18
Identities = 27/126 (21%), Positives = 62/126 (49%), Gaps = 17/126 (13%)
Query: 71 SWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDV 130
+W+Q +L + K+ ++GF +++ + + + I A AG+ A D
Sbjct: 129 TWTQPRLCYLVKEGG-SYGFSLKTVQGKKG--------VYMTDITPQGVAMRAGVLADDH 179
Query: 131 LANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTE---LEAKLQVLKQTLKQ 187
L +NG + E ++++VV+ ++ SG+ + ++ K T+ +E K+Q ++T
Sbjct: 180 LIEVNGENVEDASHEEVVEKVKKSGSRVMF-----LLVDKETDKRHVEQKIQFKRETASL 234
Query: 188 KWVEYR 193
K + ++
Sbjct: 235 KLLPHQ 240
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 55.1 bits (131), Expect = 1e-07
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 15/173 (8%)
Query: 44 MLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNAC 103
M ++++ P + + +R SS + S Q ++ + +GF I++ R ++
Sbjct: 921 MSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVI---HSSGKNYGFTIRAIRVYVGDSD 977
Query: 104 SSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIET- 162
+ ++ ++E SPA AGL+AGD++ +ING G + +V++L+ SGN ++I T
Sbjct: 978 IYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTT 1037
Query: 163 -LNGTMI----------LKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLH 204
T I R +K K++L+++ ++ L Q LLH
Sbjct: 1038 PFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLH 1090
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 54.7 bits (130), Expect = 1e-07
Identities = 51/201 (25%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 10 SSNGNLADFCAG--PAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSL 67
SS+G G P +S S L+ +T DD +++ PR +R SS
Sbjct: 880 SSSGGSGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLS---PRSLSSNPSSRDSSP 936
Query: 68 S----DFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCA 123
S S R + + + +GF +++ R ++ + ++ +++ SPA A
Sbjct: 937 SRDPSPVCGSLRPPIVIHSSGKK-YGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEA 995
Query: 124 GLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELE---AKLQV 180
GL+AGD++ +ING S G + VV+L+ SGN +++ T L+ T ++ A+ V
Sbjct: 996 GLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLR----TTALENTSIKVGPARKNV 1051
Query: 181 LKQTLKQKWVEYRSLQLQEHR 201
K + ++ R + Q+ R
Sbjct: 1052 AKGRMARRSKRSRRRETQDRR 1072
>gi|45120119 microtubule associated serine/threonine kinase 1 [Homo
sapiens]
Length = 1570
Score = 51.2 bits (121), Expect = 1e-06
Identities = 33/114 (28%), Positives = 60/114 (52%), Gaps = 5/114 (4%)
Query: 53 PRGRKQLALTRSSSLS-DFSWSQ---RKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMF 108
PR +R SS S D+S + R +T+++ + +GF +++ R + +
Sbjct: 939 PRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKK-YGFTLRAIRVYMGDTDVYSVH 997
Query: 109 TLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIET 162
++ ++E PA AGL AGD++ ++NG G + +VV+LI SGN + + T
Sbjct: 998 HIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTT 1051
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 50.1 bits (118), Expect = 3e-06
Identities = 26/58 (44%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Query: 107 MFTLICK-IQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETL 163
M T+ K ++ED PAH AGL+ GD L +NG S G TY QV+ LI++S + L + +
Sbjct: 1 MDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNSDDTLELSIM 58
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 50.1 bits (118), Expect = 3e-06
Identities = 50/179 (27%), Positives = 76/179 (42%), Gaps = 31/179 (17%)
Query: 55 GRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSY------------------- 95
G++Q S FSW K VT+ K+ ++ FGF ++ +
Sbjct: 28 GKEQSETVSLSEDETFSWPGPKTVTL-KRTSQGFGFTLRHFIVYPPESAIQFSYKDEENG 86
Query: 96 -RPQNQNACSSEMFTLICK-IQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRS 153
R Q M T+ K ++E PA AGL GD + +NG S G TY QV+ LI++
Sbjct: 87 NRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQN 146
Query: 154 SGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEY-RSLQLQEHRLLHGDAANCP 211
S L + + + E LQVL+ T + Y + L+ + G+A N P
Sbjct: 147 SDTTLELSVM--------PKDEDILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARNIP 197
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 48.5 bits (114), Expect = 9e-06
Identities = 67/282 (23%), Positives = 115/282 (40%), Gaps = 32/282 (11%)
Query: 25 SSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQD 84
+S+S+ TG + + R AD + G ++ +SS++ +Q +L+TV
Sbjct: 593 ASHSSKTGKVNGMKDARPSSPADVASNSSHGYPNDTVSLASSIA----TQPELITVHIVK 648
Query: 85 NET-FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFT 143
FGF I + + ++ DSP C GL+ GD++ +N + + T
Sbjct: 649 GPMGFGFTIAD----SPGGGGQRVKQIV-----DSP-RCRGLKEGDLIVEVNKKNVQALT 698
Query: 144 YKQVVDLIRS--SGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHR 201
+ QVVD++ G+ +T+ G + + + K Q L++ Q ++ + HR
Sbjct: 699 HNQVVDMLVECPKGSEVTLLVQRGGLPVPKK--SPKSQPLERKDSQNSSQH---SVSSHR 753
Query: 202 LLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGY 261
LH PS L E F P P D + K W S +M
Sbjct: 754 SLH---TASPSHSTQVLPE---FPPAEAQAPDQTDSSGQKKPDPFKIWAQSRSMYENRPM 807
Query: 262 QTCVSEDSSRGAFSRQTSTDD--ECFIP--KEGDDFLRRSSS 299
+ S+G R+ ++ + EC IP +E D FL R +
Sbjct: 808 SPSPASGLSKGEREREINSTNFGECPIPDYQEQDIFLWRKET 849
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 9/96 (9%)
Query: 78 VTVEKQDNETFGFEIQSY--RPQNQ-----NACSSEMFTLICKIQEDSPA-HCAGLQAGD 129
V + + +NE FGF I S RP+ NAC + M I +I E SPA C L+ GD
Sbjct: 999 VEIRRGENEGFGFVIVSSVSRPEAGTTFAGNACVA-MPHKIGRIIEGSPADRCGKLKVGD 1057
Query: 130 VLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
+ +NG S ++ +V+LI+ +GN +T+ + G
Sbjct: 1058 RILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPG 1093
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 9/84 (10%)
Query: 74 QRKLVTVE-KQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAH-CAGLQAGDVL 131
++ TVE ++ + FGF ++ R N M + ++ ED PA C ++ GD +
Sbjct: 1147 EQDFYTVELERGAKGFGFSLRGGREYN-------MDLYVLRLAEDGPAERCGKMRIGDEI 1199
Query: 132 ANINGVSTEGFTYKQVVDLIRSSG 155
ING +T+ + + ++LI++ G
Sbjct: 1200 LEINGETTKNMKHSRAIELIKNGG 1223
Score = 29.3 bits (64), Expect = 5.7
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 108 FTLICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRS 153
F I + D PA G ++ GDV+ ++N G T+ QVV + +S
Sbjct: 495 FLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQS 541
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 48.5 bits (114), Expect = 9e-06
Identities = 67/282 (23%), Positives = 115/282 (40%), Gaps = 32/282 (11%)
Query: 25 SSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQD 84
+S+S+ TG + + R AD + G ++ +SS++ +Q +L+TV
Sbjct: 593 ASHSSKTGKVNGMKDARPSSPADVASNSSHGYPNDTVSLASSIA----TQPELITVHIVK 648
Query: 85 NET-FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFT 143
FGF I + + ++ DSP C GL+ GD++ +N + + T
Sbjct: 649 GPMGFGFTIAD----SPGGGGQRVKQIV-----DSP-RCRGLKEGDLIVEVNKKNVQALT 698
Query: 144 YKQVVDLIRS--SGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHR 201
+ QVVD++ G+ +T+ G + + + K Q L++ Q ++ + HR
Sbjct: 699 HNQVVDMLVECPKGSEVTLLVQRGGLPVPKK--SPKSQPLERKDSQNSSQH---SVSSHR 753
Query: 202 LLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGY 261
LH PS L E F P P D + K W S +M
Sbjct: 754 SLH---TASPSHSTQVLPE---FPPAEAQAPDQTDSSGQKKPDPFKIWAQSRSMYENRPM 807
Query: 262 QTCVSEDSSRGAFSRQTSTDD--ECFIP--KEGDDFLRRSSS 299
+ S+G R+ ++ + EC IP +E D FL R +
Sbjct: 808 SPSPASGLSKGEREREINSTNFGECPIPDYQEQDIFLWRKET 849
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 8/95 (8%)
Query: 78 VTVEKQDNETFGFEIQSY--RPQNQ----NACSSEMFTLICKIQEDSPA-HCAGLQAGDV 130
V + + +NE FGF I S RP+ NAC + M I +I E SPA C L+ GD
Sbjct: 999 VEIRRGENEGFGFVIVSSVSRPEAGTTFGNACVA-MPHKIGRIIEGSPADRCGKLKVGDR 1057
Query: 131 LANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
+ +NG S ++ +V+LI+ +GN +T+ + G
Sbjct: 1058 ILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPG 1092
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 9/84 (10%)
Query: 74 QRKLVTVE-KQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAH-CAGLQAGDVL 131
++ TVE ++ + FGF ++ R N M + ++ ED PA C ++ GD +
Sbjct: 1146 EQDFYTVELERGAKGFGFSLRGGREYN-------MDLYVLRLAEDGPAERCGKMRIGDEI 1198
Query: 132 ANINGVSTEGFTYKQVVDLIRSSG 155
ING +T+ + + ++LI++ G
Sbjct: 1199 LEINGETTKNMKHSRAIELIKNGG 1222
Score = 29.3 bits (64), Expect = 5.7
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 108 FTLICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRS 153
F I + D PA G ++ GDV+ ++N G T+ QVV + +S
Sbjct: 495 FLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQS 541
>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
sapiens]
Length = 1798
Score = 47.8 bits (112), Expect = 2e-05
Identities = 22/75 (29%), Positives = 43/75 (57%)
Query: 88 FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQV 147
+GF +++ R ++ + ++ +++ PA AGL+ GD++ ++NG G + +V
Sbjct: 1114 YGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEV 1173
Query: 148 VDLIRSSGNLLTIET 162
V+LI SGN + I T
Sbjct: 1174 VELILKSGNKVAIST 1188
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo
sapiens]
Length = 1747
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/96 (30%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 76 KLVTVEKQDNETFGFEIQSYRPQN--QNACSSEMFTLICKIQE---DSPAHCAGLQAGDV 130
K+ ++K+D+E FGF ++ + + + + F + ++ + A AGL+ GD
Sbjct: 586 KVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDF 645
Query: 131 LANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGT 166
L +NGV+ +KQVV LIR GN L ++ ++ T
Sbjct: 646 LIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVT 681
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 8/95 (8%)
Query: 78 VTVEKQDNETFGFEIQSY--RPQNQ----NACSSEMFTLICKIQEDSPA-HCAGLQAGDV 130
V + + +NE FGF I S RP+ NAC + M I +I E SPA C L+ GD
Sbjct: 971 VEIRRGENEGFGFVIVSSVSRPEAGTTFGNACVA-MPHKIGRIIEGSPADRCGKLKVGDR 1029
Query: 131 LANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
+ +NG S ++ +V+LI+ +GN +T+ + G
Sbjct: 1030 ILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPG 1064
Score = 42.0 bits (97), Expect = 9e-04
Identities = 55/234 (23%), Positives = 95/234 (40%), Gaps = 28/234 (11%)
Query: 25 SSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQD 84
+S+S+ TG + + R AD + G ++ +SS++ +Q +L+TV
Sbjct: 593 ASHSSKTGKVNGMKDARPSSPADVASNSSHGYPNDTVSLASSIA----TQPELITVHIVK 648
Query: 85 NET-FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFT 143
FGF I + + ++ DSP C GL+ GD++ +N + + T
Sbjct: 649 GPMGFGFTIAD----SPGGGGQRVKQIV-----DSP-RCRGLKEGDLIVEVNKKNVQALT 698
Query: 144 YKQVVDLIRS--SGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHR 201
+ QVVD++ G+ +T+ G + + + K Q L++ Q ++ + HR
Sbjct: 699 HNQVVDMLVECPKGSEVTLLVQRGGLPVPKK--SPKSQPLERKDSQNSSQH---SVSSHR 753
Query: 202 LLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTM 255
LH PS L E F P P D + K W S +M
Sbjct: 754 SLH---TASPSHSTQVLPE---FPPAEAQAPDQTDSSGQKKPDPFKIWAQSRSM 801
Score = 39.3 bits (90), Expect = 0.006
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 9/84 (10%)
Query: 74 QRKLVTVE-KQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAH-CAGLQAGDVL 131
++ TVE ++ + FGF ++ R N M + ++ ED PA C ++ GD +
Sbjct: 1118 EQDFYTVELERGAKGFGFSLRGGREYN-------MDLYVLRLAEDGPAERCGKMRIGDEI 1170
Query: 132 ANINGVSTEGFTYKQVVDLIRSSG 155
ING +T+ + + ++LI++ G
Sbjct: 1171 LEINGETTKNMKHSRAIELIKNGG 1194
Score = 29.3 bits (64), Expect = 5.7
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 108 FTLICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRS 153
F I + D PA G ++ GDV+ ++N G T+ QVV + +S
Sbjct: 495 FLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQS 541
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
Length = 2161
Score = 47.0 bits (110), Expect = 3e-05
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 74 QRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFT---------LICKIQEDSPAHCAG 124
+ K V ++K+D+E FGF ++ + Q E FT + + E A AG
Sbjct: 660 KEKTVLLQKKDSEGFGFVLRGAKAQTP----IEEFTPTPAFPALQYLESVDEGGVAWRAG 715
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETL 163
L+ GD L +NG + ++QVV++IR GN L ++ +
Sbjct: 716 LRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVV 754
>gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2
[Homo sapiens]
Length = 281
Score = 45.8 bits (107), Expect = 6e-05
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 13/102 (12%)
Query: 74 QRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFT---------LICKIQEDSPAHCAG 124
+ K V ++K+DNE FGF ++ + E FT + + E A AG
Sbjct: 35 EEKTVVLQKKDNEGFGFVLRGAKADTP----IEEFTPTPAFPALQYLESVDEGGVAWQAG 90
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGT 166
L+ GD L +N + ++QVV++IR GN L ++ + T
Sbjct: 91 LRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVT 132
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 45.8 bits (107), Expect = 6e-05
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 13/102 (12%)
Query: 74 QRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFT---------LICKIQEDSPAHCAG 124
+ K V ++K+DNE FGF ++ + E FT + + E A AG
Sbjct: 623 EEKTVVLQKKDNEGFGFVLRGAKADTP----IEEFTPTPAFPALQYLESVDEGGVAWQAG 678
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGT 166
L+ GD L +N + ++QVV++IR GN L ++ + T
Sbjct: 679 LRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVT 720
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Query: 71 SWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFT--LICKIQEDSPAHCAG-LQA 127
+W+Q + V + ++ +++ G I R + E+ I + EDSPA G L+
Sbjct: 1145 NWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKP 1204
Query: 128 GDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQ 187
GD + ++G+ +++Q V+ IR +GN + + I+ R ++ L L L
Sbjct: 1205 GDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQS---IINRPR-KSPLPSLLHNLYP 1260
Query: 188 KWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCK 247
K+ + + ++ D A PS + ++ L P P A + ++SS
Sbjct: 1261 KYNFSSTNPFADSLQINADKA--PSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSAS 1318
Query: 248 SWLSSMTMDSEDGY 261
+ + E GY
Sbjct: 1319 KISQDVDKEDEFGY 1332
Score = 33.9 bits (76), Expect = 0.23
Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Query: 121 HCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV 180
H +Q GD + ++G + +GFT +Q V+++R +G + + TL + + EL ++ V
Sbjct: 418 HDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLL-TLMRRGMKQEAELMSREDV 476
Query: 181 LK 182
K
Sbjct: 477 TK 478
Score = 33.9 bits (76), Expect = 0.23
Identities = 14/41 (34%), Positives = 26/41 (63%)
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
L+ GD + I G STEG T+ Q V+L++++ + ++ + G
Sbjct: 1878 LRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAG 1918
Score = 29.6 bits (65), Expect = 4.4
Identities = 12/40 (30%), Positives = 25/40 (62%)
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLN 164
L+ GD + +NG S EG T+++ V +++ + +T+ L+
Sbjct: 2002 LKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS 2041
>gi|169217736 PREDICTED: similar to PDZ domain containing 1 [Homo
sapiens]
Length = 227
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 9/85 (10%)
Query: 76 KLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANIN 135
KL + K +N +GF + NA + I ++Q+ PA AGL+ DV+ +N
Sbjct: 56 KLCRLAKGENG-YGFHL--------NAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVN 106
Query: 136 GVSTEGFTYKQVVDLIRSSGNLLTI 160
GV+ Y++VVD I+SSG +T+
Sbjct: 107 GVNVLDEPYEKVVDRIQSSGKNVTL 131
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 78 VTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA-HCAGLQAGDVLANING 136
V + +++NE FGF I S + ++ + + I +I + SPA CA L+ GD + +NG
Sbjct: 921 VVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNG 980
Query: 137 VSTEGFTYKQVVDLIRSSGNLLTIETL 163
S + +V LI+ +G +T+ +
Sbjct: 981 QSIINMPHADIVKLIKDAGLSVTLRII 1007
Score = 42.4 bits (98), Expect = 7e-04
Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 10/108 (9%)
Query: 62 TRSSSLSDFSWSQR-KLVTVEKQDN-ETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSP 119
TR LSD+ Q TV+ + + FGF I+ R +M + ++ ED P
Sbjct: 1129 TRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREY-------KMDLYVLRLAEDGP 1181
Query: 120 AHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGT 166
A G ++ GD + ING ST T+ + ++LI+S G + + GT
Sbjct: 1182 AIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGT 1229
Score = 28.5 bits (62), Expect = 9.7
Identities = 10/31 (32%), Positives = 20/31 (64%)
Query: 122 CAGLQAGDVLANINGVSTEGFTYKQVVDLIR 152
C GL GD++ IN + + ++ +VVD+++
Sbjct: 637 CPGLCEGDLIVEINQQNVQNLSHTEVVDILK 667
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRS 153
I +++ SPA A L+AGD L +NGV+ EG T+ QVV I++
Sbjct: 36 IRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKA 78
Score = 36.2 bits (82), Expect = 0.047
Identities = 39/152 (25%), Positives = 57/152 (37%), Gaps = 42/152 (27%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILK 170
I + SPA +GL+A D L +NG + EG + +VV I K
Sbjct: 176 IRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASI------------------K 217
Query: 171 RTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGP 230
E EA+L V+ + + R +EH + GPLP P
Sbjct: 218 AREDEARLLVVDPETDEHFKRLRVTPTEEH----------------------VEGPLPSP 255
Query: 231 GPALVDRNRLSSESSC--KSWLSSMTMDSEDG 260
+L+ S+C +S L D+EDG
Sbjct: 256 VTNGTSPAQLNGGSACSSRSDLPGSDKDTEDG 287
>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
[Homo sapiens]
Length = 326
Score = 42.7 bits (99), Expect = 5e-04
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRS 153
I +++ SPA A L+AGD L +NGV+ EG T+ QVV I++
Sbjct: 36 IRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKA 78
Score = 32.7 bits (73), Expect = 0.52
Identities = 34/138 (24%), Positives = 50/138 (36%), Gaps = 40/138 (28%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILK 170
I + SPA +GL+A D L +NG + EG + +VV I K
Sbjct: 176 IRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASI------------------K 217
Query: 171 RTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGP 230
E EA+L V+ + + R +EH + GPLP P
Sbjct: 218 AREDEARLLVVDPETDEHFKRLRVTPTEEH----------------------VEGPLPSP 255
Query: 231 GPALVDRNRLSSESSCKS 248
+L+ S+C S
Sbjct: 256 VTNGTSPAQLNGGSACSS 273
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
Query: 88 FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQ 146
FGF ++ + N M I ++ ED PA G + GD + ING T+G T+ +
Sbjct: 1031 FGFSLRGGKEYN-------MGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTR 1083
Query: 147 VVDLIRSSGNLLTIETLNGTMIL 169
++LI++ GN + + GT ++
Sbjct: 1084 AIELIQAGGNKVLLLLRPGTGLI 1106
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 78 VTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA-HCAGLQAGDVLANING 136
V +++++NE FGF I + + + I ++ E SPA C L+ GD ++ +NG
Sbjct: 852 VVLQRKENEGFGFVILTSKNKPPPGVIPHK---IGRVIEGSPADRCGKLKVGDHISAVNG 908
Query: 137 VSTEGFTYKQVVDLIRSSGNLLTIETL 163
S ++ +V LI+ +G +T+ +
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTLTVI 935
Score = 29.3 bits (64), Expect = 5.7
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 122 CAGLQAGDVLANINGVSTEGFTYKQVVDLIR 152
C GLQ GD++ I + + T+ QVV++++
Sbjct: 610 CQGLQKGDIIKEIYHQNVQNLTHLQVVEVLK 640
Score = 28.5 bits (62), Expect = 9.7
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 128 GDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLN-GTMILKRTELEAKLQVLKQTLK 186
GDVL +NG G T + + +IR + ++T+ G +I K LQ K ++
Sbjct: 68 GDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSID 127
Query: 187 QK 188
K
Sbjct: 128 HK 129
Score = 28.5 bits (62), Expect = 9.7
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 24/77 (31%)
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLI----RSSGNLLT--------------------I 160
L+A D L I+G+ +G ++KQV+DL+ R+ LLT I
Sbjct: 767 LRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDDSSQAFI 826
Query: 161 ETLNGTMILKRTELEAK 177
T NG+ L R E+ A+
Sbjct: 827 STQNGSPRLNRAEVPAR 843
>gi|155969695 membrane-associated guanylate kinase-related 3 isoform
2 [Homo sapiens]
Length = 1125
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 8/83 (9%)
Query: 88 FGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQ 146
FGF ++ + N M I ++ ED PA G + GD + ING T+G T+ +
Sbjct: 1031 FGFSLRGGKEYN-------MGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTR 1083
Query: 147 VVDLIRSSGNLLTIETLNGTMIL 169
++LI++ GN + + GT ++
Sbjct: 1084 AIELIQAGGNKVLLLLRPGTGLI 1106
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 78 VTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA-HCAGLQAGDVLANING 136
V +++++NE FGF I + + + I ++ E SPA C L+ GD ++ +NG
Sbjct: 852 VVLQRKENEGFGFVILTSKNKPPPGVIPHK---IGRVIEGSPADRCGKLKVGDHISAVNG 908
Query: 137 VSTEGFTYKQVVDLIRSSGNLLTIETL 163
S ++ +V LI+ +G +T+ +
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTLTVI 935
Score = 29.3 bits (64), Expect = 5.7
Identities = 11/31 (35%), Positives = 20/31 (64%)
Query: 122 CAGLQAGDVLANINGVSTEGFTYKQVVDLIR 152
C GLQ GD++ I + + T+ QVV++++
Sbjct: 610 CQGLQKGDIIKEIYHQNVQNLTHLQVVEVLK 640
Score = 28.5 bits (62), Expect = 9.7
Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 128 GDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLN-GTMILKRTELEAKLQVLKQTLK 186
GDVL +NG G T + + +IR + ++T+ G +I K LQ K ++
Sbjct: 68 GDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSID 127
Query: 187 QK 188
K
Sbjct: 128 HK 129
Score = 28.5 bits (62), Expect = 9.7
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 24/77 (31%)
Query: 125 LQAGDVLANINGVSTEGFTYKQVVDLI----RSSGNLLT--------------------I 160
L+A D L I+G+ +G ++KQV+DL+ R+ LLT I
Sbjct: 767 LRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDDSSQAFI 826
Query: 161 ETLNGTMILKRTELEAK 177
T NG+ L R E+ A+
Sbjct: 827 STQNGSPRLNRAEVPAR 843
>gi|9507165 syntrophin, gamma 2 [Homo sapiens]
Length = 539
Score = 42.0 bits (97), Expect = 9e-04
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 75 RKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAG-LQAGDVLAN 133
R+ VT+ +Q G I+ N + +I KI ED A G L GD +
Sbjct: 71 RRTVTLRRQPVGGLGLSIKGGSEHN-------VPVVISKIFEDQAADQTGMLFVGDAVLQ 123
Query: 134 INGVSTEGFTYKQVVDLIRSSGNLLTI 160
+NG+ E T+++VV L+R++G+ +TI
Sbjct: 124 VNGIHVENATHEEVVHLLRNAGDEVTI 150
>gi|223890252 glutamate receptor interacting protein 1 [Homo sapiens]
Length = 1076
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 22/156 (14%)
Query: 51 TLPR--GRKQLALTRSSS-----LSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNAC 103
TLP GRK + L + +S K+ + D E FGF +
Sbjct: 920 TLPSDVGRKSVTLRKMKQEIKEIMSPTPVELHKVTLYKDSDMEDFGFSVADGL------- 972
Query: 104 SSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETL 163
E + I+ P GL+ D L +N V T F VV LI SGN L
Sbjct: 973 -LEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKL----- 1026
Query: 164 NGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQE 199
+++ R L ++ + +Q+L W E S Q+
Sbjct: 1027 --DLVISRNPLASQKSIDQQSLPGDWSEQNSAFFQQ 1060
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/46 (45%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 110 LICKIQEDSPAH-CAGLQAGDVLANINGVSTEGFTYKQVVDLIRSS 154
LI I+ DSPA C LQ GD + ING+ TE T+++ L+R S
Sbjct: 450 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDS 495
Score = 30.0 bits (66), Expect = 3.3
Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 77 LVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPA-HCAGLQAGDVLANIN 135
LV V K + G + + + C ++ +I KI+ S A C L GD + +I+
Sbjct: 252 LVEVAKTPGASLGVALTT------SMCCNKQVIVIDKIKSASIADRCGALHVGDHILSID 305
Query: 136 GVSTEGFTYKQVVDLIRSSGNLLTIETL 163
G S E T + + ++ + + +E L
Sbjct: 306 GTSMEYCTLAEATQFLANTTDQVKLEIL 333
Score = 29.6 bits (65), Expect = 4.4
Identities = 25/122 (20%), Positives = 53/122 (43%), Gaps = 16/122 (13%)
Query: 59 LALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDS 118
LA+ R S +F S +V + K++ T G + ++ S + Q
Sbjct: 37 LAVRRQSIPEEFKGST--VVELMKKEGTTLGLTVSGGIDKDGKPRVSNLR------QGGI 88
Query: 119 PAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIE--------TLNGTMILK 170
A L GD + +NG++ F + +++ L+++ G + +E ++ G+ ++
Sbjct: 89 AARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGSSVIF 148
Query: 171 RT 172
RT
Sbjct: 149 RT 150
>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
sapiens]
Length = 358
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 18/102 (17%)
Query: 99 NQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLL 158
N ++ S+ I + DSPA +GL+A D + +NGV EG + VV IR+ G+
Sbjct: 167 NLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGD-- 224
Query: 159 TIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEH 200
E KL V+ + + + + R + QEH
Sbjct: 225 ----------------ETKLLVVDRETDEFFKKCRVIPSQEH 250
Score = 39.7 bits (91), Expect = 0.004
Identities = 20/47 (42%), Positives = 30/47 (63%)
Query: 114 IQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTI 160
++ SPA AGL AGD L +NG + E T++QVV IR++ N + +
Sbjct: 42 VEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRL 88
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMI 168
I ++ E+ PA AG++ GD L +NGV+ +G + + V+ +R +G + + M+
Sbjct: 760 ISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMV 817
Score = 31.2 bits (69), Expect = 1.5
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 114 IQEDSPAHCAG----LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
I + SP AG L+ G L +N S G T+ + V L+RS G+ LT+ +G
Sbjct: 1136 ISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDG 1191
Score = 28.9 bits (63), Expect = 7.5
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 111 ICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTI 160
+ +I E AH AG LQ GD + +INGV + V L+ ++ + +
Sbjct: 894 VSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIAL 944
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 111 ICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMI 168
I ++ E+ PA AG++ GD L +NGV+ +G + + V+ +R +G + + M+
Sbjct: 760 ISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMV 817
Score = 31.2 bits (69), Expect = 1.5
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 114 IQEDSPAHCAG----LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNG 165
I + SP AG L+ G L +N S G T+ + V L+RS G+ LT+ +G
Sbjct: 1136 ISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDG 1191
Score = 28.9 bits (63), Expect = 7.5
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 111 ICKIQEDSPAHCAG-LQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTI 160
+ +I E AH AG LQ GD + +INGV + V L+ ++ + +
Sbjct: 894 VSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIAL 944
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/41 (46%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 116 EDSPAH-CAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSG 155
+D PA C L+ GD++ +ING ST+G T+ Q V+ IR+ G
Sbjct: 91 KDGPAQRCGRLEVGDLVLHINGESTQGLTHAQAVERIRAGG 131
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/41 (46%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 116 EDSPAH-CAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSG 155
+D PA C L+ GD++ +ING ST+G T+ Q V+ IR+ G
Sbjct: 158 KDGPAQRCGRLEVGDLVLHINGESTQGLTHAQAVERIRAGG 198
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,438,948
Number of Sequences: 37866
Number of extensions: 574058
Number of successful extensions: 2433
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 107
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2169
Number of HSP's gapped (non-prelim): 327
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.