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Search of human proteins with 47933339
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47933339 RNA binding motif protein 15 [Homo sapiens]
(977 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47933339 RNA binding motif protein 15 [Homo sapiens] 1959 0.0
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 613 e-175
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 122 1e-27
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 62 3e-09
gi|109240550 paraspeckle protein 1 [Homo sapiens] 60 8e-09
gi|57864582 hornerin [Homo sapiens] 60 1e-08
gi|47132620 keratin 2 [Homo sapiens] 58 5e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 57 1e-07
gi|109255251 loricrin [Homo sapiens] 56 2e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 2e-07
gi|55956899 keratin 9 [Homo sapiens] 55 2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 55 2e-07
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 55 4e-07
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 55 4e-07
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 54 5e-07
gi|195972866 keratin 10 [Homo sapiens] 54 7e-07
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 54 7e-07
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 54 7e-07
gi|119395750 keratin 1 [Homo sapiens] 54 9e-07
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 54 9e-07
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 54 9e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 53 1e-06
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 53 2e-06
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 52 2e-06
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 52 3e-06
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 52 3e-06
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 52 3e-06
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 52 3e-06
gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d ... 52 3e-06
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 52 3e-06
>gi|47933339 RNA binding motif protein 15 [Homo sapiens]
Length = 977
Score = 1959 bits (5076), Expect = 0.0
Identities = 977/977 (100%), Positives = 977/977 (100%)
Query: 1 MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRG 60
MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRG
Sbjct: 1 MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRG 60
Query: 61 GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSS 120
GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSS
Sbjct: 61 GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSS 120
Query: 121 SRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQ 180
SRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQ
Sbjct: 121 SRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQ 180
Query: 181 LSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVL 240
LSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVL
Sbjct: 181 LSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVL 240
Query: 241 YDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAAL 300
YDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAAL
Sbjct: 241 YDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAAL 300
Query: 301 GYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFRE 360
GYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFRE
Sbjct: 301 GYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFRE 360
Query: 361 VDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLK 420
VDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLK
Sbjct: 361 VDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLK 420
Query: 421 FENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGT 480
FENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGT
Sbjct: 421 FENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGT 480
Query: 481 IRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQP 540
IRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQP
Sbjct: 481 IRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQP 540
Query: 541 LPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRT 600
LPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRT
Sbjct: 541 LPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRT 600
Query: 601 AATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESD 660
AATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESD
Sbjct: 601 AATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESD 660
Query: 661 RPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRK 720
RPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRK
Sbjct: 661 RPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRK 720
Query: 721 NSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASA 780
NSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASA
Sbjct: 721 NSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASA 780
Query: 781 SPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQP 840
SPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQP
Sbjct: 781 SPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQP 840
Query: 841 KLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQA 900
KLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQA
Sbjct: 841 KLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQA 900
Query: 901 AGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQI 960
AGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQI
Sbjct: 901 AGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQI 960
Query: 961 GVRYENKKRENLALTLL 977
GVRYENKKRENLALTLL
Sbjct: 961 GVRYENKKRENLALTLL 977
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 613 bits (1580), Expect = e-175
Identities = 414/932 (44%), Positives = 515/932 (55%), Gaps = 94/932 (10%)
Query: 59 RGGEDSTSRG---ERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTG 115
RG S R ER + GG ++ +S G R S GG R+ G
Sbjct: 14 RGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRD---G 70
Query: 116 GGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS-------------GAASSAPG 162
G+ + + S S+ + +GGG + G G S S GA + PG
Sbjct: 71 RGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPG 130
Query: 163 GGDGA-EYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVN 221
A EYKTL IS L L E +ED LFH+FKRFG++S+++SH G RVA+VN
Sbjct: 131 SSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELG----RVAYVN 186
Query: 222 FRRPEDARAAK-HARGR-LVLYDRPLKIEAVYV------SRRRSRSPLDKDTYPPSASVV 273
FR P+DAR A+ HA R L+LYDRPLK+E VY+ SRR S S T PP
Sbjct: 187 FRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAP 246
Query: 274 GASVGGHRHPPGGGG---GQRSLSPGGAALGYRDYRLQQLALG-RLPPPPPPPLPRDLER 329
+G + P GG QRSLSP AA R+ R + A L + ER
Sbjct: 247 ADPLG---YLPLHGGYQYKQRSLSPV-AAPPLREPRARHAAAAFALDAAAAAAVGLSRER 302
Query: 330 ERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESD 389
DY Y L G G E D + PEDDQRA R LF+GNLD +V+E +
Sbjct: 303 ALDY---------YGLYDDRGRPYGYPAVCEED-LMPEDDQRATRNLFIGNLDHSVSEVE 352
Query: 390 LRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYG 449
LRRAF+++G+I EV IKRP+RGQ Y FLKF+NLDM+HRAK+AMSG++I RNPIKIGYG
Sbjct: 353 LRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYG 412
Query: 450 KATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTH 509
KA PTTRLWVGGLGP LAALAREFDRFG+IRTID+ KGDS+AYIQYESLDAA AA
Sbjct: 413 KANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAK 472
Query: 510 MRGFPLGGPDRRLRVDFADTEH-RYQQQYLQPLPL-THYELVTDAFGHRAPDPLRGARDR 567
MRGFPLGGPDRRLRVDFA E RY QQY QP PL HYEL+TD + RDR
Sbjct: 473 MRGFPLGGPDRRLRVDFAKAEETRYPQQY-QPSPLPVHYELLTDGYTRHRNLDADLVRDR 531
Query: 568 TPP-LLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRD 626
TPP LLY DRDR + + DW P R+ S+ Y R + W D
Sbjct: 532 TPPHLLYSDRDR-TFLEGDWTSPSKSSDRRN------SLEGYS-RSVRSRSGERWGAD-- 581
Query: 627 RGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKR----HCAPSPDRSPELSSSRD 682
GDR LP ++ RKRR GR SP +R R + DR+PE S +
Sbjct: 582 -GDRGLPKPWEERRKRRSLSSDRGR-TTHSPYEERSRTKGSGQQSERGSDRTPERSRKEN 639
Query: 683 RYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSP 742
+ SS L + RG + + +R HRTT P
Sbjct: 640 HSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAE--PKP 697
Query: 743 LKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSN 802
L++ + KLK+ S+ + L L W G+L+LKNS FP++
Sbjct: 698 LEEPKHE----------TKKLKNLSE-----------YAQTLQLGWNGLLVLKNSCFPTS 736
Query: 803 MHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLA 862
MH+L+GD V SSLL + ++G K+ QLKI QRLRLDQPKLDEVTRRIK PNGYA+LLA
Sbjct: 737 MHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLA 796
Query: 863 VPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHA 922
+ + + +R LRNLVSYLKQKQAAGVISLPVGG+K ++ TG+L+A
Sbjct: 797 TQATPSGLGTEGMPTVEPGLQ-RRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYA 855
Query: 923 FPPCEFSQQFLDSPAKALAKSEEDYLVMIIVR 954
FPPC+FSQQ+L S + L K EE+++V++IVR
Sbjct: 856 FPPCDFSQQYLQSALRTLGKLEEEHMVIVIVR 887
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 122 bits (307), Expect = 1e-27
Identities = 118/445 (26%), Positives = 193/445 (43%), Gaps = 41/445 (9%)
Query: 358 FREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYG 417
FR +DE E +A RTLF+GNL+ T T DLR F RFG I ++DIK+ + Y
Sbjct: 422 FRPLDERIDEFHPKATRTLFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNG--VPQYA 479
Query: 418 FLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDR 477
FL++ ++ +A M G+ + N +K+G+GK+ PT +W+ GL V L R F R
Sbjct: 480 FLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTNCVWLDGLSSNVSDQYLTRHFCR 539
Query: 478 FGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQY 537
+G + + + + A + Y ++ A AA +G +GG +++VDFA+ E + +
Sbjct: 540 YGPVVKVVFDRLKGMALVLYNEIEYAQAAVKETKGRKIGG--NKIKVDFANRESQLAFYH 597
Query: 538 LQPLP----LTHYELVTDAFGHRAPDPLRGARDRTPPLLYRD--RDRDLYPDSDWVPPPP 591
YE++ + R R + D Y + R YP+ P
Sbjct: 598 CMEKSGQDIRDFYEMLAERREER-----RASYDYNQDRTYYESVRTPGTYPEDSRRDYPA 652
Query: 592 PVRERSTRTAATSVPAYE------PLDSLDRRRDGWSLD----------RDRGDRDLPSS 635
RE + YE P + D R D + D R+R S
Sbjct: 653 RGREFYSEWETYQGDYYESRYYDDPREYRDYRNDPYEQDIREYSYRQRERERERERFESD 712
Query: 636 RDQPRKRRLPEESGGRHLDRSP-ESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRS-SR 693
RD+ +RR E S +SP RP+ +PS S R Y+ +DRS S
Sbjct: 713 RDRDHERRPIERS------QSPVHLRRPQSPGASPSQAERLPSDSERRLYSRSSDRSGSC 766
Query: 694 LLLERPSPIRDRRGSLEK-SQGDKRDRKNSASAER-DRKHRTTAPTEGKSPLKKEDRSDG 751
L P + + LE+ ++ +K D++ + ER +R+ R + + + + G
Sbjct: 767 SSLSPPRYEKLDKSRLERYTKNEKTDKERTFDPERVERERRLIRKEKVEKDKTDKQKRKG 826
Query: 752 SAPSTSTASSKLKSPSQKQDGGTAP 776
S S+ SS+ ++++ P
Sbjct: 827 KVHSPSSQSSETDQENEREQSPEKP 851
Score = 84.0 bits (206), Expect = 6e-16
Identities = 69/229 (30%), Positives = 97/229 (42%), Gaps = 22/229 (9%)
Query: 722 SASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGT------- 774
S S + D T K PL S S P P+ KQD
Sbjct: 3436 SVSMKPDLPVSLPTQTAPKQPLFVPTTSGPSTPPGLVLPHTEFQPAPKQDSSPHLTSQRP 3495
Query: 775 APVASASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQR 834
+ K + WQG+L LKN +H + G+ +A L G L+I QR
Sbjct: 3496 VDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLPLSEGG---PPLRIAQR 3552
Query: 835 LRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSY 894
+RL+ +L+ V RR+ V Y +LLA+P D D + T+ ++Y
Sbjct: 3553 MRLEATQLEGVARRMTVE--TDYCLLLALPCGRDQE--------DVVSQTESLKAAFITY 3602
Query: 895 LKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKS 943
L+ KQAAG+I++P G+ + VL FPPCEFS+ L A L S
Sbjct: 3603 LQAKQAAGIINVPNPGS--NQPAYVLQIFPPCEFSESHLSRLAPDLLAS 3649
Score = 68.9 bits (167), Expect = 2e-11
Identities = 77/270 (28%), Positives = 114/270 (42%), Gaps = 39/270 (14%)
Query: 10 PRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGE 69
PR PR R L S R + DD+ R + ER+ + RSR S SR +
Sbjct: 199 PRYEPRAREQFTL--PSVVHR--DIYRDDITREVRGRRPERN-YQHSRSRSPHSSQSRNQ 253
Query: 70 RSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSP 129
++L S S ++ SG GSR SR + SSSS S SS
Sbjct: 254 SPQRLA----SQASRPTRSPSGSGSR-------------SRSSSSDSISSSSSTSSDSSD 296
Query: 130 STKNSSGGGESRSSSRGGGGESRS---SGAASSAPGGGDGAEYKTLKISELGSQLSDEAV 186
S+ +SS +RS S S P G +K+ L + +D ++
Sbjct: 297 SSSSSSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFG-----IKVQNLPVRSTDTSL 351
Query: 187 EDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLK 246
+DGLFHEFK+FG K++ + G+ +ER V FR+ ED A A + + ++
Sbjct: 352 KDGLFHEFKKFG----KVTSVQIHGTSEERYGLVFFRQQEDQEKALTASKGKLFFGMQIE 407
Query: 247 IEAVYVSRRRSRS---PLDK--DTYPPSAS 271
+ A S + PLD+ D + P A+
Sbjct: 408 VTAWIGPETESENEFRPLDERIDEFHPKAT 437
Score = 48.5 bits (114), Expect = 3e-05
Identities = 98/410 (23%), Positives = 145/410 (35%), Gaps = 84/410 (20%)
Query: 371 RANRTLFLGNLDITVTESDLRRAFDRFGVITEVDI--KRPSRGQTSTY-GFLKFENLDMS 427
R R L++GNL V E + F R+G + V I KR S G + + F+ ++ +
Sbjct: 3 RETRHLWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGSEGGVAAFVDFVDIKSAQKA 62
Query: 428 HRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYR 487
H + M + ++ Y + T GL V +A+ +RE F
Sbjct: 63 HNSVNKMGDR-----DLRTDYNE-PGTIPSAARGLDDTVSIASRSREVSGF-------RG 109
Query: 488 KGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYE 547
G AY SL A G +RRL + E Y+ H+E
Sbjct: 110 GGGGPAYGPPPSLHARE-----------GRYERRLDGASDNRERAYEHS-----AYGHHE 153
Query: 548 LVTDAFG---HRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATS 604
T F H D R R+RT LY S R RS
Sbjct: 154 RGTGGFDRTRHYDQDYYRDPRERT-------LQHGLYYAS---------RSRSPNRFDAH 197
Query: 605 VPAYEPLDSLDRRRDGWSLDRDRGDRDLPS--SRDQPRKRRLPEESGGRHLDRSPESDRP 662
P YEP R R LPS RD R + E GR +R+ + R
Sbjct: 198 DPRYEP--------------RAREQFTLPSVVHRDIYRD-DITREVRGRRPERNYQHSRS 242
Query: 663 RKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNS 722
R H + S ++SP+ RL + P R GS +S+ D +S
Sbjct: 243 RSPHSSQSRNQSPQ----------------RLASQASRPTRSPSGSGSRSRSSSSDSISS 286
Query: 723 ASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDG 772
+S+ +++ + SP + + AP++ SS K +K G
Sbjct: 287 SSSTSSDSSDSSSSSSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFG 336
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 61.6 bits (148), Expect = 3e-09
Identities = 62/228 (27%), Positives = 90/228 (39%), Gaps = 20/228 (8%)
Query: 556 RAPDPLRGARDRTPPLLYRDRDRDLYP----DSDWVPPPPPVRERSTRTAATSVPAYEPL 611
R+P+ R P RDR R P D P R+RS + +
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 612 DSLDRRRD-----GWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRH 666
S ++ RD S +RD PS R+ R P + RS +R +R
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
Query: 667 CAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAE 726
+PS +R S S N + DRS PS R+ R S S+ R R S S E
Sbjct: 525 RSPSKERQRRQSRSP---NKERDRSQS---RSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
Query: 727 RDRKHRTTAPTE-----GKSPLKKEDRSDGSAPSTSTASSKLKSPSQK 769
R+R+ ++ E +SP K+ S A S A S+ ++PS++
Sbjct: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
Score = 60.5 bits (145), Expect = 8e-09
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 9/151 (5%)
Query: 625 RDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSP--DRSPELSSSRD 682
RDR P+ + R P ++ R RSP R R +P+ DRS S S++
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 683 RYNSDNDRSSRLLLERPS--PIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGK 740
R +S S+ R S P ++R+ +S +RD + S S ++R+ R + +
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR-----QSR 537
Query: 741 SPLKKEDRSDGSAPSTSTASSKLKSPSQKQD 771
SP K+ DRS +PS + +SPS+++D
Sbjct: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKERD 568
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 24/195 (12%)
Query: 592 PVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPR---KRRLPEES 648
P +ERS + +S S +R G S R R S ++ R + R P ++
Sbjct: 359 PSKERSHSHSRSS--------SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410
Query: 649 GGRHLDRSPESDRPRKRHCAP------SPDRSPELSSSRDRYNSDNDRSSRLLLERPSPI 702
R RSP R R R +P S RSP + R R S N P+
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKA 470
Query: 703 RDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPT------EGKSPLKKEDRSDGSAPST 756
RDR S S+ + S S ERD + R+ +P+ + +S K+ D +PS
Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHR-RSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
Query: 757 STASSKLKSPSQKQD 771
+ +SP++++D
Sbjct: 530 ERQRRQSRSPNKERD 544
Score = 48.5 bits (114), Expect = 3e-05
Identities = 45/165 (27%), Positives = 67/165 (40%), Gaps = 19/165 (11%)
Query: 617 RRDGWSLDRDRGDRDLPSSRDQPRKR-----RLPEESGGRHLDRSPESDRPRKRHCAPSP 671
R WS + + +R SR ++R P + GR SP R R +P+
Sbjct: 351 RSHNWSRNPSK-ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
Query: 672 DRSPELSSS----RDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRD--RKNSASA 725
R S S RDR S + +R SP + R S +S RD R S +
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 726 ERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQ 770
RDR + +SP K+ D S +PS + +SPS+++
Sbjct: 470 ARDR-------SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Score = 48.1 bits (113), Expect = 4e-05
Identities = 54/232 (23%), Positives = 81/232 (34%), Gaps = 17/232 (7%)
Query: 556 RAPDPLRGARDRTPPLLYRDRDRDLYP--DSDWVPPPPPVRERSTRTAATSVPAYEPLDS 613
R+P+ R P RDR R P + D P +ER R + + + S
Sbjct: 453 RSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQS 512
Query: 614 LD-------RRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRH 666
RR S +R R P+ + R P E RSP +R R+R
Sbjct: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW 572
Query: 667 CAPSPDR--------SPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRD 718
+PS +R S E SR R + SR R + K +
Sbjct: 573 RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQS 632
Query: 719 RKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQ 770
R +S ++ + +P +SP + S PS +++ S PS Q
Sbjct: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684
Score = 47.4 bits (111), Expect = 7e-05
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 643 RLPEESGGRHLDRSPESDRPRKRHCAPSPDR------SPELSSSRDRYNSDNDRSSRLLL 696
R P + R+P +R + S +R SP S R + S N +
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
Query: 697 ERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPST 756
P+ RDR S + R R S + RD + +SP K DRS +P+
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARD-------CSRSRSPYKARDRSRSRSPNK 457
Query: 757 STASSKLKSPSQKQD 771
+ S+ +SP++ +D
Sbjct: 458 ARDHSRSRSPNKARD 472
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 18/146 (12%)
Query: 635 SRDQPRKRRLPEESGGRHLD-RSPESDRPRKRHCAPSPDRSPELSS--SRDRYNSDNDRS 691
SR + R R+ GRH RS + + + P RS S S++R +S + S
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
Query: 692 SRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAP------TEGKSPLKK 745
S+ RD RGS + R + S + +RD R+ +P + +SP K
Sbjct: 372 SKE--------RDHRGSSSPRKESGRSQSGSPNKQRDHS-RSRSPNKARDRSRSRSPYKA 422
Query: 746 EDRSDGSAPSTSTASSKLKSPSQKQD 771
DRS +P+ + S+ +SP + +D
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARD 448
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 60.5 bits (145), Expect = 8e-09
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 7/106 (6%)
Query: 376 LFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMS 435
LF+GNL +TE D +R F+R+G +EV I R RG +GF++ E+ ++ AK +
Sbjct: 84 LFVGNLPTDITEEDFKRLFERYGEPSEVFINR-DRG----FGFIRLESRTLAEIAKAELD 138
Query: 436 GKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTI 481
G I+ P++I + AT L V L P V L + F +FG +
Sbjct: 139 GTILKSRPLRIRF--ATHGAALTVKNLSPVVSNELLEQAFSQFGPV 182
Score = 33.5 bits (75), Expect = 1.00
Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 4/125 (3%)
Query: 434 MSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWA 493
M I I++ +K G T RL+VG L + R F+R+G + + +
Sbjct: 61 MGFTIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFG 120
Query: 494 YIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAF 553
+I+ ES A A + G L R LR+ FA H P+ EL+ AF
Sbjct: 121 FIRLESRTLAEIAKAELDGTIL--KSRPLRIRFA--THGAALTVKNLSPVVSNELLEQAF 176
Query: 554 GHRAP 558
P
Sbjct: 177 SQFGP 181
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 60.1 bits (144), Expect = 1e-08
Identities = 57/183 (31%), Positives = 68/183 (37%), Gaps = 28/183 (15%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG-----SNGSSSGKTDSGGGSRRSLHLD 101
G +SP + G S+S G G S G S+G SSG T G GS S +
Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958
Query: 102 KSSSRGGSREYDTGGGSSSSRLHSYSSPST---------KNSSGGGESRSSSRG----GG 148
+ SR G GSSS SY + ++ SG G+S S SRG G
Sbjct: 959 QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
Query: 149 GESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLS 208
G+S S G S G S G S GL H R G S H S
Sbjct: 1019 GQSSSYGPYRSGSGWS----------SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
Query: 209 GSG 211
SG
Sbjct: 1069 SSG 1071
Score = 57.4 bits (137), Expect = 6e-08
Identities = 56/193 (29%), Positives = 71/193 (36%), Gaps = 34/193 (17%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG----------GSGGSNG---------SSSGK 87
G +SP + + G S+S G+ G GSG S+G SSG
Sbjct: 1355 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGC 1414
Query: 88 TDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPST---------KNSSGGG 138
T G GS S ++ SR G GSSS SY + ++ SG G
Sbjct: 1415 TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 1474
Query: 139 ESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFG 198
+S S SRG G ++ S G G G S G S + GL H R G
Sbjct: 1475 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWS------SSRGPYESGSSHSSGLGHRESRSG 1528
Query: 199 DVSVKISHLSGSG 211
S H S SG
Sbjct: 1529 QSSGYGQHGSSSG 1541
Score = 57.4 bits (137), Expect = 6e-08
Identities = 56/193 (29%), Positives = 70/193 (36%), Gaps = 34/193 (17%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG----------GSGGSNG---------SSSGK 87
G +SP + + G S+S G+ G GSG S+G SSG
Sbjct: 2295 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGY 2354
Query: 88 TDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPST---------KNSSGGG 138
T G GS S ++ SR G GSSS SY + ++ SG G
Sbjct: 2355 TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 2414
Query: 139 ESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFG 198
+S S SRG G ++ S G G G S G S GL H R G
Sbjct: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWS------SSRGPYESGSGHSSGLGHRESRSG 2468
Query: 199 DVSVKISHLSGSG 211
S H S SG
Sbjct: 2469 QSSGYGQHGSSSG 2481
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/193 (30%), Positives = 73/193 (37%), Gaps = 34/193 (17%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG----------GSGGSNG---------SSSGK 87
G +SP + + G S+S G+ G GSG S+G SSG
Sbjct: 1825 GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGY 1884
Query: 88 TDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPST---------KNSSGGG 138
T G GS S ++ SR G GSSS SY + ++ SG G
Sbjct: 1885 TQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 1944
Query: 139 ESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFG 198
+S S SRG G SG +SS G G+ + S G S GL H R G
Sbjct: 1945 QSPSPSRGRHGS--GSGQSSSYGPYGSGSGWS----SSRGPYESGSGHSSGLGHRESRSG 1998
Query: 199 DVSVKISHLSGSG 211
S H S SG
Sbjct: 1999 QSSGYGQHGSSSG 2011
Score = 53.5 bits (127), Expect = 9e-07
Identities = 60/193 (31%), Positives = 76/193 (39%), Gaps = 34/193 (17%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG----------GSGGSNG---------SSSGK 87
G +SP +R G S S G+ G GSG S+G SSG
Sbjct: 419 GSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGY 478
Query: 88 TDSGGGSRRSLHLDKSSSRG-----GSREYDTGGGSSSSRLHSYSSPS----TKNSSGGG 138
T G GS S + SR G R+ + G SSS H S +++ SG G
Sbjct: 479 TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSG 538
Query: 139 ESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFG 198
+S S SR G ES S ++S P G Y + + S G S GL H+ R G
Sbjct: 539 QSPSPSR-GRHESGSRQSSSYGPHG-----YGSGRSSSRGPYESGSGHSSGLGHQESRSG 592
Query: 199 DVSVKISHLSGSG 211
S H S SG
Sbjct: 593 QSSGYGQHGSSSG 605
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/180 (29%), Positives = 64/180 (35%), Gaps = 23/180 (12%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG------SNGSSSGKTDSGGGSRRSLHL 100
G +SP + G S+S G+ LG S G S+G SS + G GS S
Sbjct: 2544 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2603
Query: 101 DKSSSRGGSREYDTGGGSSSSRLHSY---------SSPSTKNSSGGGESRSSSRGGGGES 151
+ SR G GSSS Y SS + SG G+S S R G G
Sbjct: 2604 GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 2663
Query: 152 RSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
SS G G + + S LG E G H S H SGSG
Sbjct: 2664 HSSSHGQHGSGSGRSSSRGPYE-SRLGHSSVFGQHESGSGHS-------SAYSQHGSGSG 2715
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/133 (32%), Positives = 54/133 (40%), Gaps = 15/133 (11%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG------SNGSSSGKTDSGGGSRRSLHL 100
G +SP + G S+S G+ LG S G S+G SS + G GS S
Sbjct: 1604 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 1663
Query: 101 DKSSSRGGSREYDTGGGS---SSSRLHSYSSPSTKNS------SGGGESRSSSRGGGGES 151
+ SR G GS SSSR + S S ++S SG G+S S R G G
Sbjct: 1664 GQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 1723
Query: 152 RSSGAASSAPGGG 164
SS G G
Sbjct: 1724 HSSSHGQHGSGSG 1736
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/133 (32%), Positives = 53/133 (39%), Gaps = 15/133 (11%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG------SNGSSSGKTDSGGGSRRSLHL 100
G +SP + G S+S G+ LG S G S+G SS + G GS S
Sbjct: 2074 GSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2133
Query: 101 DKSSSRGGSREYDTGGGS---SSSRLHSYSSPSTKNS------SGGGESRSSSRGGGGES 151
+ SR G GS SSSR + S S ++S SG G S S R G G
Sbjct: 2134 GQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSG 2193
Query: 152 RSSGAASSAPGGG 164
SS G G
Sbjct: 2194 HSSSHGQHGSGSG 2206
Score = 52.0 bits (123), Expect = 3e-06
Identities = 43/125 (34%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSS 105
G +SP +R G S S G GSG SSSG+ SG G H + SS
Sbjct: 1591 GSGQSPGHGQRGSGSRQSPSYGRH-----GSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645
Query: 106 RGGSREYDTGGGSSSSRLHSYSSPSTKNSSG---GGESRSSSR---GGGGESRSSGAASS 159
+ S G SS + S S ++S G G SRSSSR G G +SSG
Sbjct: 1646 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQ 1705
Query: 160 APGGG 164
G G
Sbjct: 1706 GSGSG 1710
Score = 51.2 bits (121), Expect = 5e-06
Identities = 41/133 (30%), Positives = 49/133 (36%), Gaps = 15/133 (11%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG------SNGSSSGKTDSGGGSRRSLHL 100
G +SP + G S+S G+ LG S G S+G SS + G GS S
Sbjct: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 1193
Query: 101 DKSSSRGGSREYDTGGGSSSSRLHSY---------SSPSTKNSSGGGESRSSSRGGGGES 151
+ SR G GSSS Y SS + SG G S S R G G
Sbjct: 1194 GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLG 1253
Query: 152 RSSGAASSAPGGG 164
SS G G
Sbjct: 1254 HSSSHGQHGSGSG 1266
Score = 48.5 bits (114), Expect = 3e-05
Identities = 44/148 (29%), Positives = 55/148 (37%), Gaps = 7/148 (4%)
Query: 76 GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLH------SYSSP 129
GS SSSG+ DS G S +S+S S G GS S H S SP
Sbjct: 845 GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP 904
Query: 130 ST-KNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVED 188
S ++ SG G S SS R G G +SSG + G + S S
Sbjct: 905 SYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRS 964
Query: 189 GLFHEFKRFGDVSVKISHLSGSGSGDER 216
G ++ G S S GSG +
Sbjct: 965 GQSSRSEQHGSSSGSSSSYGQHGSGSRQ 992
Score = 47.8 bits (112), Expect = 5e-05
Identities = 45/160 (28%), Positives = 61/160 (38%), Gaps = 11/160 (6%)
Query: 64 STSRGERSKKLGGSG--GSNGSSSGKTDS----GGGSRRSLHLDKSSSRGGSREYDTGGG 117
S++ G+ G S G +G+SSG++ S G GS +S + S G G
Sbjct: 1073 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1132
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTL-KISE 176
S S + SY ++ SG G S SS + G G SSG G + Y S
Sbjct: 1133 SGSRQSPSYG----RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1188
Query: 177 LGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDER 216
S G +R G S SH GSG +
Sbjct: 1189 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228
Score = 47.8 bits (112), Expect = 5e-05
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSS 105
G +SP +R G S S G GSG SSSG+ SG G H + SS
Sbjct: 1121 GSGQSPGHGQRGSGSRQSPSYGRH-----GSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175
Query: 106 RGGSREYDTGGGSSSSRLHSYSSPSTKNSSG---GGESRSSS---RGGGGESRSSGAASS 159
+ S G SS + S S ++S G G S SSS + G G +SSG
Sbjct: 1176 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
Query: 160 APGGG 164
G G
Sbjct: 1236 GSGSG 1240
Score = 47.8 bits (112), Expect = 5e-05
Identities = 45/160 (28%), Positives = 61/160 (38%), Gaps = 11/160 (6%)
Query: 64 STSRGERSKKLGGSG--GSNGSSSGKTDS----GGGSRRSLHLDKSSSRGGSREYDTGGG 117
S++ G+ G S G +G+SSG++ S G GS +S + S G G
Sbjct: 2483 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 2542
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTL-KISE 176
S S + SY ++ SG G S SS + G G SSG G + Y S
Sbjct: 2543 SGSRQSPSYG----RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 2598
Query: 177 LGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDER 216
S G +R G S SH GSG +
Sbjct: 2599 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 2638
Score = 47.8 bits (112), Expect = 5e-05
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSS 105
G +SP +R G S S G GSG SSSG+ SG G H + SS
Sbjct: 2531 GSGQSPGHGQRGSGSRQSPSYGRH-----GSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
Query: 106 RGGSREYDTGGGSSSSRLHSYSSPSTKNSSG---GGESRSSS---RGGGGESRSSGAASS 159
+ S G SS + S S ++S G G S SSS + G G +SSG
Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 2645
Query: 160 APGGG 164
G G
Sbjct: 2646 GSGSG 2650
Score = 47.4 bits (111), Expect = 7e-05
Identities = 42/126 (33%), Positives = 54/126 (42%), Gaps = 14/126 (11%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSR 106
G+ SP + + G S+S G GSG SS G +SG G L + S
Sbjct: 1944 GQSPSPSRGRHGSGSGQSSSYGPY-----GSGSGWSSSRGPYESGSGHSSGLG-HRESRS 1997
Query: 107 GGSREYDTGGGSS--SSRLHSYSSPSTKNSSGG------GESRSSSRGGGGESRSSGAAS 158
G S Y G SS SS + S S ++SS G G+S S + G G S+SSG
Sbjct: 1998 GQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2057
Query: 159 SAPGGG 164
G G
Sbjct: 2058 QGSGSG 2063
Score = 47.4 bits (111), Expect = 7e-05
Identities = 41/125 (32%), Positives = 50/125 (40%), Gaps = 12/125 (9%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSS 105
G +SP +R G S S G GSG SSSG+ G G H + SS
Sbjct: 2061 GSGQSPGHGQRGSGSRQSPSYGRH-----GSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115
Query: 106 RGGSREYDTGGGSSSSRLHSYSSPSTKNSSG---GGESRSSSR---GGGGESRSSGAASS 159
+ S G SS + S S ++S G G S SSSR G G +SSG
Sbjct: 2116 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQ 2175
Query: 160 APGGG 164
G G
Sbjct: 2176 GSGSG 2180
Score = 47.0 bits (110), Expect = 9e-05
Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 16/178 (8%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG--GSGGSNGSSSG-------KTDSGGGSRRS 97
G +SP + + S+S G+ G S G +GS SG K+ SG S S
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 98 LHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGG--GESRSSSRGGGGESRSSG 155
H SS G R++ + G SS R + S S +SS G G S G G + SG
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSS-RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG 773
Query: 156 AASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSG 213
+ S G + + S G S + H G S H SGSG G
Sbjct: 774 HSPSRVRHGSSSGHS----SSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG 827
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/132 (31%), Positives = 55/132 (41%), Gaps = 14/132 (10%)
Query: 41 RPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHL 100
R + G+ SP + + G S+S G G G SS G +SG G L
Sbjct: 532 RHGSGSGQSPSPSRGRHESGSRQSSSYGPH-----GYGSGRSSSRGPYESGSGHSSGLGH 586
Query: 101 DKSSSRGGSREYDTGGGSS--SSRLHSYSSPSTKNSSGG------GESRSSSRGGGGESR 152
+S S G S Y G SS SS + S S ++SS G G+S S + G G S+
Sbjct: 587 QESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQ 645
Query: 153 SSGAASSAPGGG 164
SS G G
Sbjct: 646 SSRYGQQGSGSG 657
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/124 (34%), Positives = 50/124 (40%), Gaps = 27/124 (21%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL------------------- 98
SR G+ +SRGER G S+GSSS G GSR+SL
Sbjct: 1432 SRSGQ--SSRGERH------GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1483
Query: 99 HLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAAS 158
H S Y +G G SSSR S S + G ESRS G G+ SS S
Sbjct: 1484 HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHS 1543
Query: 159 SAPG 162
S G
Sbjct: 1544 STHG 1547
Score = 46.2 bits (108), Expect = 1e-04
Identities = 56/189 (29%), Positives = 67/189 (35%), Gaps = 31/189 (16%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSR 106
G SP + + S+S G+ GSG S SS G +SG G +S S
Sbjct: 771 GSGHSPSRVRHGSSSGHSSSHGQH-----GSGTSCSSSCGHYESGSGQASGFGQHESGSG 825
Query: 107 GG--------------SREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRS---SSRG--G 147
G R T G SSSS H SS +S G ES S S RG G
Sbjct: 826 QGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHD-SSSGQSSSYGQHESASHHASGRGRHG 884
Query: 148 GGESRSSGAASSAPGGGDGAEY-----KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSV 202
G +S G G G Y + + S G S G H+ G S
Sbjct: 885 SGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK-SSSGQSSG 943
Query: 203 KISHLSGSG 211
H SGSG
Sbjct: 944 YTQHGSGSG 952
Score = 46.2 bits (108), Expect = 1e-04
Identities = 45/164 (27%), Positives = 62/164 (37%), Gaps = 8/164 (4%)
Query: 56 KRSRGGEDSTSRGERSKKLGGSG--GSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYD 113
+ SR G+ S+ G+ G S G +GS+SG++ S G S S + GS
Sbjct: 1993 RESRSGQ-SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGA-----E 168
+ G S + SG +S S R G G RSS + PG G+ + E
Sbjct: 2052 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHE 2111
Query: 169 YKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGS 212
+ + S S G R G S H S SGS
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGS 2155
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 14/164 (8%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGS-------SSGKTDSGGGSRRS-LHLDKSSSRGGS 109
SR G+ +SRGER + GS S G S G G GSR+S H+ S G S
Sbjct: 262 SRSGQ--SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHS 319
Query: 110 REYDT-GGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESR-SSGAASSAPGGGDGA 167
+ G GSS S + + +SG G+ S S G S+ SG+ S+ G G+
Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379
Query: 168 EYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
S S ++ G R S + H SGSG
Sbjct: 380 TSGQASSSGQHGSSSRQSSSYGQHESASRHS--SGRGQHSSGSG 421
Score = 45.8 bits (107), Expect = 2e-04
Identities = 64/271 (23%), Positives = 87/271 (32%), Gaps = 60/271 (22%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSR 106
G +SP + G S+S G+ GSG S S G +SG G +S S
Sbjct: 302 GSRQSPSHVRHGSGSGHSSSHGQH-----GSGSSYSYSRGHYESGSGQTSGFGQHESGSG 356
Query: 107 GGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSR--------------------- 145
S G GS S ++ +S G+ SSSR
Sbjct: 357 QSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQH 416
Query: 146 -GGGGES-----RSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGD 199
G G+S R SG+ S G G + + S G +S G H
Sbjct: 417 SSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG--RSSSSGPYVSGSGYSSGFGHHESSSEH 474
Query: 200 VSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRS 259
S H SGSG + +R+ + +RG R+ S
Sbjct: 475 SSGYTQHGSGSGHS-------SGHGQHGSRSGQSSRG-----------------ERQGSS 510
Query: 260 PLDKDTYPPSASVVGASVGGHRHPPGGGGGQ 290
+Y S S+G RH G G GQ
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRH--GSGSGQ 539
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/165 (27%), Positives = 64/165 (38%), Gaps = 17/165 (10%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKT------DSGGGSRRSLHLDKSSSRGGSRE 111
S G+ + G S S G +GS+SG++ DS G S +S+S S
Sbjct: 822 SGSGQGYSQHGSASGHFS-SQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGR 880
Query: 112 YDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKT 171
G GS S H + SG G+S S R G G RSS + G G + +
Sbjct: 881 GRHGSGSGQSPGHG------QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGH 934
Query: 172 LKISELGSQLSDEAVEDGLFHEFKRFGDVSVKIS----HLSGSGS 212
S S + G +++ G S + S H S SGS
Sbjct: 935 KSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/188 (28%), Positives = 67/188 (35%), Gaps = 26/188 (13%)
Query: 47 GKERSPVKAKRSRGGEDSTSRG----------ERSKKLGGSGGSNGSSSGKTDSGGGSRR 96
G+ SP + + G S+S G R GSG S+G ++ SG S
Sbjct: 1004 GQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 1063
Query: 97 SLHLDKSSSRGGSREY----DTGGGSSSSRLHSYSS--PSTKNSSGGGESRSSSRG--GG 148
H SS G S + T G SSS H SS S+ G G S+SS G G
Sbjct: 1064 GQH---GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 1120
Query: 149 GESRSSGAASSAPGGGDGAEY-----KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVK 203
G +S G G Y + + S G S G H G S
Sbjct: 1121 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 1180
Query: 204 ISHLSGSG 211
H SGSG
Sbjct: 1181 SQHGSGSG 1188
Score = 45.1 bits (105), Expect = 3e-04
Identities = 51/166 (30%), Positives = 65/166 (39%), Gaps = 18/166 (10%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSR----EYD 113
SR G+ +SRGER G S+GSSS G GSR+S + S G +
Sbjct: 2138 SRSGQ--SSRGERH------GSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 2189
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA---PGGGDG---A 167
+G G SSS S +S G ESRS G+ S SSA G G G +
Sbjct: 2190 SGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2249
Query: 168 EYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSG 213
+ + S S E G + G S + S GSG
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSG 2295
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/115 (35%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
SRG S S S GSG SS G +SG G L + S G S Y G
Sbjct: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG-HRESRSGQSSGYGQHGS 2478
Query: 118 SS--SSRLHSYSSPSTKNSSGG------GESRSSSRGGGGESRSSGAASSAPGGG 164
SS SS + S S ++SS G G+S S + G G S+SSG G G
Sbjct: 2479 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2533
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/179 (28%), Positives = 67/179 (37%), Gaps = 21/179 (11%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSR 106
G +SP + G S+S GSG S+G S K+ SG S S H S
Sbjct: 198 GSGQSPNYGQHGSGSGQSSSNDTHGS---GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS 254
Query: 107 GGSREYDTGGGSSS-SRLHSYSSPST----KNSSGGGESRSSSRGGGGESRS-------- 153
G ++ + G SS H SS S+ ++ SG +S R G G +S
Sbjct: 255 SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGS 314
Query: 154 -SGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
SG +SS G G+ Y + G S G G S H SGSG
Sbjct: 315 GSGHSSSHGQHGSGSSYSYSR----GHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG 369
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 6/151 (3%)
Query: 25 TSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSS 84
+++G +Q R ++ G+ S S G +S S + GSG
Sbjct: 833 SASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPG 892
Query: 85 SGKTDSGGGSRRSL--HLDKSSSRGGSREYDTGGGSSSSRLHSYSSPS----TKNSSGGG 138
G+ SG G S H S S + +G G SS H SS T++ SG G
Sbjct: 893 HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG 952
Query: 139 ESRSSSRGGGGESRSSGAASSAPGGGDGAEY 169
S S + G +SS + G + Y
Sbjct: 953 HSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY 983
Score = 44.7 bits (104), Expect = 4e-04
Identities = 44/160 (27%), Positives = 60/160 (37%), Gaps = 11/160 (6%)
Query: 64 STSRGERSKKLGGSG--GSNGSSSGKTDS----GGGSRRSLHLDKSSSRGGSREYDTGGG 117
S++ G+ G S G +G+SSG++ S G GS +S + S G G
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG 1602
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTL-KISE 176
S S + SY ++ SG G S SS + G G SSG G + Y S
Sbjct: 1603 SGSRQSPSYG----RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 1658
Query: 177 LGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDER 216
S G +R G S S GSG +
Sbjct: 1659 HSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ 1698
Score = 44.3 bits (103), Expect = 6e-04
Identities = 51/185 (27%), Positives = 63/185 (34%), Gaps = 20/185 (10%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSR 106
G+ SP + + G S+S G S SG + S G R +SS
Sbjct: 1474 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGY 1533
Query: 107 G--GS---------REYDTGGGSSSSRLHSYSS--PSTKNSSGGGESRSSSRG--GGGES 151
G GS + T G SSS H SS S+ G G S+SS G G G
Sbjct: 1534 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 1593
Query: 152 RSSGAASSAPGGGDGAEY-----KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISH 206
+S G G Y + + S G S G H G S H
Sbjct: 1594 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 1653
Query: 207 LSGSG 211
SGSG
Sbjct: 1654 GSGSG 1658
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/98 (34%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S+G STS +S G S G SS G GS +S + S G G
Sbjct: 1779 SQGQHGSTSG--QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 1836
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG 155
S S SY ++ SG G S SS R G G +SSG
Sbjct: 1837 SGSGHSSSYG----QHGSGSGWSSSSGRHGSGSGQSSG 1870
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/141 (31%), Positives = 57/141 (40%), Gaps = 27/141 (19%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSSRGGSRE----- 111
SR G+ +SRGE+ G S+GSSS G GSR+SL H S G S
Sbjct: 1902 SRSGQ--SSRGEQH------GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1953
Query: 112 -------------YDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAAS 158
Y +G G SSSR S + G ESRS G G+ SS S
Sbjct: 1954 HGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS 2013
Query: 159 SAPGGGDGAEYKTLKISELGS 179
S G A ++ + G+
Sbjct: 2014 STHGQHGSASGQSSSCGQHGA 2034
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/98 (34%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S+G STS +S G S G SS G GS +S + S G G
Sbjct: 2249 SQGQHGSTSG--QSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 2306
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG 155
S S SY ++ SG G S SS R G G +SSG
Sbjct: 2307 SGSGHSSSYG----QHGSGSGWSSSSGRHGSGSGQSSG 2340
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/188 (28%), Positives = 66/188 (35%), Gaps = 26/188 (13%)
Query: 47 GKERSPVKAKRSRGGEDSTS----------RGERSKKLGGSGGSNGSSSGKTDSGGGSRR 96
G+ SP + + G S+S R GSG S+G ++ SG S
Sbjct: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 2473
Query: 97 SLHLDKSSSRGGSREY----DTGGGSSSSRLHSYSS--PSTKNSSGGGESRSSSRG--GG 148
H SS G S + T G SSS H SS S+ G G S+SS G G
Sbjct: 2474 GQH---GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2530
Query: 149 GESRSSGAASSAPGGGDGAEY-----KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVK 203
G +S G G Y + + S G S G H G S
Sbjct: 2531 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 2590
Query: 204 ISHLSGSG 211
H SGSG
Sbjct: 2591 SQHGSGSG 2598
Score = 43.9 bits (102), Expect = 7e-04
Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 15/138 (10%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSG------GSNGSSSGKTDSGGGSRRSLHL 100
G S + G S+SRG +LG S +G SS + G GS
Sbjct: 2661 GLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2720
Query: 101 DKSSSRGGSREYDTGGGSSSSRLHSY---------SSPSTKNSSGGGESRSSSRGGGGES 151
+ S G GSS+ + SY SS ++ +G G+S S R G G
Sbjct: 2721 GQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSG 2780
Query: 152 RSSGAASSAPGGGDGAEY 169
+SS G G + Y
Sbjct: 2781 QSSSYGQHGSGSGQSSGY 2798
Score = 43.5 bits (101), Expect = 0.001
Identities = 41/161 (25%), Positives = 59/161 (36%), Gaps = 25/161 (15%)
Query: 24 ETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGS 83
++S G R G R G +S ++ G S SRG GSG + S
Sbjct: 2142 QSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRH-----GSGSGHSS 2196
Query: 84 SSGKTDSGGG--SRRSLHLDKSSSRGGSREYDTGGGSSSS------------------RL 123
S G+ SG G S R + +S ++++G G SS+
Sbjct: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 2256
Query: 124 HSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGG 164
SS + S G+S S + G G S+SS G G
Sbjct: 2257 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG 2297
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/173 (30%), Positives = 68/173 (39%), Gaps = 22/173 (12%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSR----EYD 113
SR G+ +SRGER G S+GSSS G GSR+S + S G +
Sbjct: 1198 SRSGQ--SSRGERH------GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHG 1249
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA---PGGGDG---A 167
+G G SSS S +S G ESRS G+ S SSA G G G +
Sbjct: 1250 SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1309
Query: 168 EYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKIS----HLSGSGSGDER 216
+ + S S E G + G S + S H +GSG R
Sbjct: 1310 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/162 (28%), Positives = 58/162 (35%), Gaps = 17/162 (10%)
Query: 24 ETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLG-------- 75
++S G R G G +S ++ G S SRG LG
Sbjct: 2612 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQH 2671
Query: 76 GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS----SSRLHSYSS--P 129
GSG SS G +S G S+ S G S Y G S S H +S
Sbjct: 2672 GSGSGRSSSRGPYESRLG-HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2730
Query: 130 STKNSSGGGESRSSSRG--GGGESRSSGAASSAPGGGDGAEY 169
ST + G +SSS G G G S+SSG G G +
Sbjct: 2731 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSH 2772
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/134 (30%), Positives = 50/134 (37%), Gaps = 17/134 (12%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLG--------GSGGSNGSSSGKTDSGGGSRRSL 98
G +S ++ G S SRG LG GSG SS G +S G S+
Sbjct: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG-HSSV 1753
Query: 99 HLDKSSSRGGSREYDTGGGSS----SSRLHSYSS--PSTKNSSGGGESRSSSRG--GGGE 150
S G S Y G S S H +S ST + G +SSS G G G
Sbjct: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 1813
Query: 151 SRSSGAASSAPGGG 164
S+SS G G
Sbjct: 1814 SQSSSYGQQGSGSG 1827
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 62 EDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSS 121
E S++ S GSG S SS G+ SG G S S S G S Y G S
Sbjct: 1796 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS-GHSSSYGQHGSGS-- 1852
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
+SS S ++ SG G+S +SSG G G + Y+
Sbjct: 1853 ---GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE 1898
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 62 EDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSS 121
E S++ S GSG S SS G+ SG G S S S G S Y G S
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS-GHSSSYGQHGSGS-- 2322
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
+SS S ++ SG G+S +SSG G G + Y+
Sbjct: 2323 ---GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE 2368
Score = 42.0 bits (97), Expect = 0.003
Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 29/178 (16%)
Query: 58 SRGGEDSTSRGER-------SKKLG--GSGGSNGSSSGKTDSGGGS-----RRSLHLDKS 103
SR G+ +SRGER S + G GSG S G+ SG G R L S
Sbjct: 1668 SRSGQ--SSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
Query: 104 SSRGGSREYDTGGGSSSSR-----LHSYSSPSTKNSSGGGESRSSSRGGGGESR-----S 153
SS G ++ +G G SSSR +SS ++ SG G S + S+ G G
Sbjct: 1726 SSHG---QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1782
Query: 154 SGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
G+ S D T + S G S + + G + H SGSG
Sbjct: 1783 HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 1840
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/180 (27%), Positives = 59/180 (32%), Gaps = 23/180 (12%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSG------GSNGSSSGKTDSGGGSRRSLHL 100
G S + G S+SRG + G S +G SS + G GS
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
Query: 101 DKSSSRGG-----SREYDTGGGSSSSRLH----SYSSPSTKNSSGGGESRSSSRGGGGES 151
+ S G +E + G SSS H S SS + SG G+S S R G G
Sbjct: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
Query: 152 RSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
SS G G S G S G H S H SGSG
Sbjct: 2311 HSSSYGQHGSGSGWS--------SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG 2362
Score = 41.6 bits (96), Expect = 0.004
Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 6/137 (4%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGG--SRRSLHLDKSS 104
G+ S S G ++S S + GSG + G+ SG G S H S
Sbjct: 167 GQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG 226
Query: 105 SRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGE--SRSSSRGGGGESRSSGAASSAPG 162
G ++ + G SS +S + +SSG G+ SRS G RSS +SS+ G
Sbjct: 227 QSSGFSQHKSSSGQSSG--YSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYG 284
Query: 163 GGDGAEYKTLKISELGS 179
++L GS
Sbjct: 285 QHGSGSRQSLGHGRQGS 301
Score = 41.6 bits (96), Expect = 0.004
Identities = 50/176 (28%), Positives = 64/176 (36%), Gaps = 24/176 (13%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGG-----SRRSLHLD 101
G+ S S G +TS S GSG S S G+ SG G R
Sbjct: 611 GQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG 670
Query: 102 KSSSRGGSREYDTGGG-SSSSRLH---SYSSPSTKNSSGGGESRSSSRGGGGESRSSGAA 157
SSS G ++ +G G SSS+ H S S + SG G+S S+ G G S SSG
Sbjct: 671 HSSSYG---QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYR 727
Query: 158 SSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSG 213
G S+ GL + + G S + S GSG
Sbjct: 728 KHGSRSGQ------------SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/117 (30%), Positives = 46/117 (39%), Gaps = 7/117 (5%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S G+ ST E S G S SG + S G R +S SRG R G
Sbjct: 1315 STSGQSSTFDQEGSST-GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRG--RHGSGSGH 1371
Query: 118 SSSSRLHS----YSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
SSS H +SS S ++ SG G+S +SSG G G + Y+
Sbjct: 1372 SSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYE 1428
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 7/129 (5%)
Query: 48 KERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL--HLDKSSS 105
+E S S G S S S GSG S G+ SG G S H S
Sbjct: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
Query: 106 RGGSREYDTGGGSSSSRLHS-----YSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA 160
S + +G G SS H SS T++ SG G S S + G +SS
Sbjct: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHG 1914
Query: 161 PGGGDGAEY 169
G + Y
Sbjct: 1915 SSSGSSSSY 1923
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 2/123 (1%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSSS 105
G+ S + G + S SR S GSG + SS G+ SG S H + S
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343
Query: 106 R-GGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGG 164
+ G ++++G G SS S +S G S S G+ SS SS+ G
Sbjct: 344 QTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQH 403
Query: 165 DGA 167
+ A
Sbjct: 404 ESA 406
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/229 (24%), Positives = 71/229 (31%), Gaps = 49/229 (21%)
Query: 24 ETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSG--GSN 81
++S G R G G +S ++ G S SRG LG S G +
Sbjct: 1202 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQH 1261
Query: 82 GSSSGKTDSGG-----GSRRSLHLDKSSSRGGSREYDTGG-------------------- 116
GS SG++ S G S+ S G S Y G
Sbjct: 1262 GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 1321
Query: 117 -----GSSSSRLHSY---------SSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPG 162
GSS+ + SY SS ++ +G G+S S R G G SS G
Sbjct: 1322 TFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSG 1381
Query: 163 GGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
G S G S G H S H SGSG
Sbjct: 1382 SGWS--------SSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG 1422
Score = 41.2 bits (95), Expect = 0.005
Identities = 49/180 (27%), Positives = 59/180 (32%), Gaps = 23/180 (12%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSG------GSNGSSSGKTDSGGGSRRSLHL 100
G S + G S+SRG + G S +G SS + G GS
Sbjct: 1721 GLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 1780
Query: 101 DKSSSRGG-----SREYDTGGGSSSSRLH----SYSSPSTKNSSGGGESRSSSRGGGGES 151
+ S G +E + G SSS H S SS + SG G+S S R G G
Sbjct: 1781 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 1840
Query: 152 RSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
SS G G S G S G H S H SGSG
Sbjct: 1841 HSSSYGQHGSGSGWS--------SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG 1892
Score = 41.2 bits (95), Expect = 0.005
Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 7/129 (5%)
Query: 48 KERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL--HLDKSSS 105
+E S S G S S S GSG S G+ SG G S H S
Sbjct: 2265 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 2324
Query: 106 RGGSREYDTGGGSSSSRLHS-----YSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA 160
S + +G G SS H SS T++ SG G S S + G +SS
Sbjct: 2325 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHG 2384
Query: 161 PGGGDGAEY 169
G + Y
Sbjct: 2385 SSSGSSSSY 2393
Score = 40.8 bits (94), Expect = 0.006
Identities = 41/139 (29%), Positives = 56/139 (40%), Gaps = 23/139 (16%)
Query: 41 RPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHL 100
R ++ G+ S + RG S S GSG SSG+ +G G
Sbjct: 395 RQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG------- 447
Query: 101 DKSSSRGGSREYDTGGGSSSSRLH-----SYSSPSTKNSSGGGESRSSSRGGG------- 148
+SSS G Y +G G SS H +SS T++ SG G S + G
Sbjct: 448 -RSSSSG---PYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSR 503
Query: 149 GESRSSGAASSAPGGGDGA 167
GE + S A SS+ G G+
Sbjct: 504 GERQGSSAGSSSSYGQHGS 522
Score = 40.8 bits (94), Expect = 0.006
Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 10/124 (8%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGG--SNGSSSGKTDSGGGSRRSLHLDKSS 104
G RS + G S+ G + + G S G +GSSSG + + G + S
Sbjct: 564 GSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623
Query: 105 SRGGSREYDTGGGSSSSRLH----SYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA 160
+ G+ T G SSS H S SS + SG G+S S R G SS
Sbjct: 624 GQHGA----TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHG 679
Query: 161 PGGG 164
G G
Sbjct: 680 SGSG 683
Score = 40.0 bits (92), Expect = 0.011
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 34/180 (18%)
Query: 46 KGKERSPVKAKRSRGGEDSTSRGERSKKLGGS-------------GGSNGSSSGKTDSGG 92
K +E S + S G DS SR R G+ G + S SG++ S G
Sbjct: 121 KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180
Query: 93 GSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESR 152
H +SS RG GS S + +Y ++ SG G+S S+ G G +
Sbjct: 181 EQNSDSH--QSSGRGQC-------GSGSGQSPNYG----QHGSGSGQSSSNDTHGSGSGQ 227
Query: 153 SSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGS 212
SSG + G + Y S+ G S G R G S H S SGS
Sbjct: 228 SSGFSQHKSSSGQSSGY-----SQHG---SGSGHSSGYGQHGSRSGQSSRGERHRSSSGS 279
Score = 40.0 bits (92), Expect = 0.011
Identities = 49/160 (30%), Positives = 56/160 (35%), Gaps = 15/160 (9%)
Query: 58 SRGGEDSTSRGERSKK-LGGSGGSNGS----SSGKTDSGGGSRRSLHLDKSSSRGGSREY 112
SR G+ S S S L S G +GS SSG G GS S S R GS
Sbjct: 731 SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHS----PSRVRHGS--- 783
Query: 113 DTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRS-SGAASSAPGGGDGAEYKT 171
G SSS S S +S G ES S G G+ S SG S G G
Sbjct: 784 --SSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841
Query: 172 LKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG 211
+ Q S D + +G H SG G
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRG 881
Score = 39.7 bits (91), Expect = 0.014
Identities = 35/127 (27%), Positives = 43/127 (33%), Gaps = 8/127 (6%)
Query: 49 ERSPVKAKRSRGGEDSTSRGERSKK-LGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRG 107
+ + S G+ S G+ S GSG S S G+ SG G S SR
Sbjct: 2018 QHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077
Query: 108 GSREYDTGGGSSSSRLHSYSSPSTKNSSG-------GGESRSSSRGGGGESRSSGAASSA 160
G GS S P SSG G+S S S+ G G SSG
Sbjct: 2078 SPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2137
Query: 161 PGGGDGA 167
G +
Sbjct: 2138 SRSGQSS 2144
Score = 36.2 bits (82), Expect = 0.15
Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S+G STS +S G S G SS G GS +S + + G G
Sbjct: 2719 SQGQHGSTSG--QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHG 2776
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS----GAASSAPGGGDGAEY 169
S S + SY ++ SG G+S S+ G G + S+ GG G+ +
Sbjct: 2777 SGSGQSSSYG----QHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYF 2828
Score = 34.3 bits (77), Expect = 0.59
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 2/132 (1%)
Query: 650 GRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSL 709
G+H RS +S R + + S S R + + R + PS +R GS
Sbjct: 258 GQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSG 317
Query: 710 EKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQK 769
S + +S S R + T G + E S S+ + S S SQ
Sbjct: 318 HSSSHGQHGSGSSYSYSRGHYESGSGQTSGFG--QHESGSGQSSGYSKHGSGSGHSSSQG 375
Query: 770 QDGGTAPVASAS 781
Q G T+ AS+S
Sbjct: 376 QHGSTSGQASSS 387
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 57.8 bits (138), Expect = 5e-08
Identities = 43/112 (38%), Positives = 48/112 (42%), Gaps = 17/112 (15%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S G S G +S GGSGG S G SGGGS GG Y +GGG
Sbjct: 533 SSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGS------------GG--RYGSGGG 578
Query: 118 SSSSRLHS--YSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGA 167
S + Y S K+SSGGG SR S GGG G +SS G A
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGG-SRGGSSSGGGYGSGGGGSSSVKGSSGEA 629
Score = 48.1 bits (113), Expect = 4e-05
Identities = 40/101 (39%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 75 GGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSR----LHSYSSPS 130
GG GG G SSG GGSRRS SR G GGG SR L S S
Sbjct: 14 GGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSIS 73
Query: 131 TKNSSGGGESRSS----SRGGG-GESRSSGAASSAPGGGDG 166
+ GGG ++ RGGG G S G S GGG G
Sbjct: 74 ISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFG 114
Score = 43.9 bits (102), Expect = 7e-04
Identities = 35/90 (38%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Query: 80 SNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGE 139
S SS T S S S ++ ++ GGS GG SS YSS S+ SGG +
Sbjct: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGS------GGRGSSSGGGYSSGSSSYGSGGRQ 545
Query: 140 SRSSSRGGGGESRSSGAASSAPGGGDGAEY 169
S S GGG S S G S GGG G Y
Sbjct: 546 SGSRGGSGGGGSISGGGYGS--GGGSGGRY 573
Score = 33.5 bits (75), Expect = 1.00
Identities = 33/119 (27%), Positives = 40/119 (33%), Gaps = 10/119 (8%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDS--GGGSRRSLHLDKSSSRGG------- 108
S G STS + GG GG G + S G G +S+ + + GG
Sbjct: 30 SGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGF 89
Query: 109 -SREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
R GGGSS +S GG G GG G PGG G
Sbjct: 90 GGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPG 148
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/346 (23%), Positives = 138/346 (39%), Gaps = 50/346 (14%)
Query: 556 RAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLD 615
R+P P +++TP L P+ P V+E ++ + VP EP+
Sbjct: 208 RSPSPAPEKKEKTPEL----------PEPSVKVKEPSVQEATSTSDILKVPKPEPIPE-- 255
Query: 616 RRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSP 675
++ + +++ +R + R R +S R RSP RPR+RH + S SP
Sbjct: 256 -PKEPSPEKNSKKEKEKEKTRPRSRSR---SKSRSRTRSRSPSHTRPRRRHRSRSRSYSP 311
Query: 676 ELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTA 735
S R S R+ + P P R RR S+ R R+ S SA +++
Sbjct: 312 RRRPSPRRRPSPRRRTPPRRM--PPPPRHRR-----SRSPVRRRRRS-SASLSGSSSSSS 363
Query: 736 PTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLK 795
+ +SP KK + S P + S SP +++ +P A+ PK +
Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH-RPSPPATPPPK----------TR 412
Query: 796 NSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVA-GP 854
+S P + + S G T GKV + K T+ + + P R+++++
Sbjct: 413 HSPTPQQSNRTRKSRVSVS----PGRTSGKVTKHKGTE--KRESPSPAPKPRKVELSESE 466
Query: 855 NGYAILLAVPGSSDSR--------SSSSSAASDTATSTQRPLRNLV 892
+A S R SSS + S +++ +RP R+ V
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
Score = 45.1 bits (105), Expect = 3e-04
Identities = 63/252 (25%), Positives = 93/252 (36%), Gaps = 53/252 (21%)
Query: 556 RAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERST-----RTAATSVPAYEP 610
R+P P R +PP+ R PPPPP R S R + S P +
Sbjct: 589 RSPSPRR----YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Query: 611 LDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPS 670
+ +RR PS + RK P S R S +P KRH +PS
Sbjct: 645 SSPVTKRRS-------------PSLSSKHRKGSSPSRS-----TREARSPQPNKRH-SPS 685
Query: 671 P-DRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDR 729
P R+P+ SSS P P+R RG+ Q +R + ++ R
Sbjct: 686 PRPRAPQTSSS------------------PPPVR--RGASSSPQ--RRQSPSPSTRPIRR 723
Query: 730 KHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQ 789
RT P + K +S S+ + S + ++K +PV S SP W
Sbjct: 724 VSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS--TNWS 781
Query: 790 GMLLLKNSNFPS 801
+ +K + P+
Sbjct: 782 PAVPVKKAKSPT 793
Score = 44.3 bits (103), Expect = 6e-04
Identities = 63/241 (26%), Positives = 90/241 (37%), Gaps = 41/241 (17%)
Query: 557 APDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVP---AYEPLDS 613
+P P R R +P R R P P PPP R RS S P Y P
Sbjct: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP-RRRSPSPRRYSPPIQRRYSPSPP 609
Query: 614 LDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDR 673
RR S P++R P R + SP P++R + R
Sbjct: 610 PKRR--------------TASPPPPPKRRASPSPPPKRRVSHSPP---PKQRSSPVTKRR 652
Query: 674 SPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGS-------LEKSQGDKRDRKNSASAE 726
SP L SS+ R S RS+R E SP ++R S + S R+ ++S+
Sbjct: 653 SPSL-SSKHRKGSSPSRSTR---EARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
Query: 727 RDRKHRTTAPTEGKSPLKK-----EDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASAS 781
+ R+ +P+ P+++ E + A S S S + S S+ G P A
Sbjct: 709 QRRQ----SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Query: 782 P 782
P
Sbjct: 765 P 765
Score = 39.7 bits (91), Expect = 0.014
Identities = 47/206 (22%), Positives = 75/206 (36%), Gaps = 25/206 (12%)
Query: 588 PPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGD--RDLPSSRDQPRKRRLP 645
P PP + R + T S + S+ R + + +G R+ PS +PRK L
Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463
Query: 646 EESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPI--- 702
E E D+ K A S + + + +SD+ SS ERP
Sbjct: 464 ES----------EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
Query: 703 -----RDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTS 757
R RR S +S ++ ++ R R+ R+ +P P + RS AP
Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP-----PPTRRRRSPSPAPPPR 568
Query: 758 TASSKLKSPSQKQDGGTAPVASASPK 783
+ P ++ S SP+
Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSPR 594
Score = 37.4 bits (85), Expect = 0.069
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 25/146 (17%)
Query: 632 LPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRS 691
L +++ ++R++ +E + + D+ K S ++ R+R S R
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK-------RERSRSPRRRK 176
Query: 692 SRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDG 751
SR PSP R +S +R+RK S S R +HRT + + +P KKE
Sbjct: 177 SR----SPSPRR-------RSSPVRRERKRSHS--RSPRHRTKSRSPSPAPEKKE----- 218
Query: 752 SAPSTSTASSKLKSPSQKQDGGTAPV 777
P S K+K PS ++ T+ +
Sbjct: 219 KTPELPEPSVKVKEPSVQEATSTSDI 244
Score = 37.4 bits (85), Expect = 0.069
Identities = 37/162 (22%), Positives = 60/162 (37%), Gaps = 18/162 (11%)
Query: 624 DRDRGDRDLPSSRDQPRKRRLP-EESGGRHLDRSPESDRPRKRHCAPSPDR--------S 674
+R R R S PR+R P R RSP R + R +P+P++
Sbjct: 167 ERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRH-RTKSRSPSPAPEKKEKTPELPE 225
Query: 675 PELSSSRDRYNSDNDRSSRLLLERPSPI-------RDRRGSLEKSQGDKRDRKNSASAER 727
P + S L + +P PI ++ EK + R R S S R
Sbjct: 226 PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSR 285
Query: 728 DRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQK 769
R R+ +P+ + + RS +P + + SP ++
Sbjct: 286 SRT-RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Score = 37.4 bits (85), Expect = 0.069
Identities = 91/405 (22%), Positives = 138/405 (34%), Gaps = 75/405 (18%)
Query: 6 RDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDST 65
R P PRR P RR P RR+ P + RSPV+ +R
Sbjct: 313 RRPSPRRRPSPRRRTP------PRRMP---------PPPRHRRSRSPVRRRR-------- 349
Query: 66 SRGERSKKLGGSGGSNGSSSGKTD-------SGGGSRRSLHLDKSSSRGGSREYDTGGGS 118
S L GS S+ SS ++ + R++ L S+S R + +
Sbjct: 350 ---RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406
Query: 119 SSSRLHSYSSPSTKNS--------SGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
+ +P N S G S ++ G E R S + + P E
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP---RKVELS 463
Query: 171 TLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARA 230
+ + G + ++V+ +++R S S S S S DER + + E R
Sbjct: 464 ESEEDKGGKMAAADSVQQR--RQYRRQNQQSSSDSG-SSSSSEDERPKRSHVKNGEVGRR 520
Query: 231 AKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDT--------YPPSASVVGASVGGHRH 282
+H+ R + + RR RSP T PP + R
Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580
Query: 283 PPGGGGGQRSLSPGGAALG-YRDYRLQQLALGRLPPPPPPPLPR--------------DL 327
P +RS SP + R Y R PPPPP R
Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640
Query: 328 ERERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEI-SPEDDQR 371
++R P +R P+ S + R G++P R E SP+ ++R
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHR----KGSSPSRSTREARSPQPNKR 681
Score = 34.7 bits (78), Expect = 0.45
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 703 RDRRGSLEK-SQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASS 761
+D+R EK S +KR+R S R RK R+ +P SP+++E + S S
Sbjct: 151 KDKRDKEEKESSREKRERSRSP---RRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS 207
Query: 762 KLKSPSQKQDGGTAPVASASPKL 784
+ SP+ ++ T + S K+
Sbjct: 208 RSPSPAPEKKEKTPELPEPSVKV 230
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 55.8 bits (133), Expect = 2e-07
Identities = 43/116 (37%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 71 SKKLGGSGGSNGSSSGKTDSGGGSRRSLHL-DKSSSRGGSREYDTGGGSSSS-------- 121
S K G GGS+G SG SGGG SS GGS + +GGG SS
Sbjct: 87 SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSS 146
Query: 122 ----------RLHSYSSPSTKNSSGGGESRSSSRGGGGE-SRSSGAASSAPGGGDG 166
+ SY S+ SSGGG SS GGGG SG S GG G
Sbjct: 147 GGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSG 202
Score = 54.3 bits (129), Expect = 5e-07
Identities = 76/267 (28%), Positives = 93/267 (34%), Gaps = 45/267 (16%)
Query: 56 KRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKT--DSGGGSRRSLHLDKSSS-------- 105
K S GG G G GGS G SSG SGGG SS
Sbjct: 18 KTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGI 77
Query: 106 ------RGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASS 159
GGS +Y GGGSS +S S GGG SS GGG SG SS
Sbjct: 78 GGCGGGSGGSVKYSGGGGSSGGGSGCFS------SGGGGSGCFSSGGGGSSGGGSGCFSS 131
Query: 160 APGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSG---SGDER 216
GG G S G S +AV + + +G VS S GSG SG
Sbjct: 132 GGGGSSGGGSGC--FSSGGGGFSGQAV------QCQSYGGVSSGGSSGGGSGCFSSGGGG 183
Query: 217 VAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRR--SRSPLDKDTYPPSASVVG 274
+ + + G + YVS ++ S + +Y +S G
Sbjct: 184 GSVCGYSGGGSGCGGGSSGGS----------GSGYVSSQQVTQTSCAPQPSYGGGSSGGG 233
Query: 275 ASVGGHRHPPGGGGGQRSLSPGGAALG 301
S G GGGGG G + +G
Sbjct: 234 GSGGSGCFSSGGGGGSSGCGGGSSGIG 260
Score = 39.3 bits (90), Expect = 0.018
Identities = 33/100 (33%), Positives = 36/100 (36%), Gaps = 13/100 (13%)
Query: 76 GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSS 135
G G S GS SG S ++ S S G S GGGS S S +
Sbjct: 197 GGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSS----GGGGSGGSGCFSSGGGGGSSGC 252
Query: 136 GGGE---------SRSSSRGGGGESRSSGAASSAPGGGDG 166
GGG S S GGG S G SS G G G
Sbjct: 253 GGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSG 292
Score = 38.1 bits (87), Expect = 0.041
Identities = 35/113 (30%), Positives = 41/113 (36%), Gaps = 21/113 (18%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGS------NGSSSGKTDSGGGSRRSLHLDKSSSRGGSRE 111
S GG S+ G GG GGS GS G SGG + + + + +
Sbjct: 165 SSGG--SSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQ 222
Query: 112 YDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGG 164
GGGSS G G S S GGGG S G SS G G
Sbjct: 223 PSYGGGSS-------------GGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSG 262
Score = 33.5 bits (75), Expect = 1.00
Identities = 32/89 (35%), Positives = 33/89 (37%), Gaps = 22/89 (24%)
Query: 75 GGSGGSNGS-SSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKN 133
GGS G GS SG SGGG GGS GGGSS
Sbjct: 227 GGSSGGGGSGGSGCFSSGGG-------------GGSS--GCGGGSSG------IGSGCII 265
Query: 134 SSGGGESRSSSRGGGGESRSSGAASSAPG 162
S GG S GGGG S G + S G
Sbjct: 266 SGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 31.6 bits (70), Expect = 3.8
Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 5/63 (7%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
GG S G G GGS+G SG SGGGS + S GG + GGS
Sbjct: 236 GGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS-----VCGGGSSGGGGGGSSVGGSG 290
Query: 120 SSR 122
S +
Sbjct: 291 SGK 293
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 12/149 (8%)
Query: 47 GKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSG----------KTDSGGGSRR 96
G +SP KA+ + G + + S S S+ SSSG K GG
Sbjct: 2539 GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG 2598
Query: 97 SLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGA 156
+ +SSR S + SSSS S SS S+ +SS S SSS S SS +
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 157 ASSAPGGGDGAEYKTLKISELGSQLSDEA 185
+SS+ + T + S S DEA
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSS--DDEA 2685
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 13/142 (9%)
Query: 43 ATMKGKERSPVKAKRSRGGEDSTSRGERS------KKLGGSGGSNGSSSGKTDSGGGSRR 96
A G E S + S G S+S S ++ G G G +G + S R
Sbjct: 2549 AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSR 2608
Query: 97 -------SLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGG 149
S SSS S + SSSS S SS S+ +SS S SSS
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
Query: 150 ESRSSGAASSAPGGGDGAEYKT 171
S ++ SS + A T
Sbjct: 2669 SSSTTDEDSSCSSDDEAAPAPT 2690
Score = 41.6 bits (96), Expect = 0.004
Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 2/110 (1%)
Query: 59 RGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGS 118
+ G+ G R+ S ++ +SS + S S S SSS S + S
Sbjct: 2589 KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 119 SSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAE 168
SSS S SS S+ +SS S SS+ S A+ AP G A+
Sbjct: 2649 SSSSSSSSSSSSSSSSS--SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQ 2696
Score = 36.6 bits (83), Expect = 0.12
Identities = 27/104 (25%), Positives = 40/104 (38%)
Query: 57 RSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGG 116
R+ S + S S S+ SSS + S S S SSS S +
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
Query: 117 GSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSA 160
SSSS S SS + ++SS + ++ G S + + A
Sbjct: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703
Score = 34.7 bits (78), Expect = 0.45
Identities = 29/119 (24%), Positives = 42/119 (35%), Gaps = 10/119 (8%)
Query: 40 RRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLH 99
R + + SP + S S+S S S S+ SSS + S S S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
Query: 100 LDKSSSRGGSREYDTGGGSSSSRLHSYSSPS----------TKNSSGGGESRSSSRGGG 148
SSS S S SS + +P+ TK + G++R S+ G
Sbjct: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPG 2718
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 55.5 bits (132), Expect = 2e-07
Identities = 46/119 (38%), Positives = 50/119 (42%), Gaps = 12/119 (10%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGS-------SSGKTDSGGGSRRSLHLDKSSSRGGS-RE 111
G ED S G LGG GGS GS SG + GGGS + S SRGGS
Sbjct: 461 GQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGG-YGGGSGSRGGSGGS 519
Query: 112 YDTGGGSSSSRLHSY---SSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGA 167
Y G GS Y S SGGG S S GG S S G + GGG G+
Sbjct: 520 YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGS 578
Score = 53.9 bits (128), Expect = 7e-07
Identities = 44/114 (38%), Positives = 49/114 (42%), Gaps = 6/114 (5%)
Query: 59 RGGED-STSRGERSKKLG--GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREY--D 113
RGG S RG R G G GGS G G + S GGS S S G Y
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 537
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGG-GGESRSSGAASSAPGGGDG 166
+GGG S +S S N GG S S GG GG S S G + + GGG G
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSG 591
Score = 52.0 bits (123), Expect = 3e-06
Identities = 40/107 (37%), Positives = 43/107 (40%), Gaps = 9/107 (8%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
GG G S GGSGGS G SG SGGGS GG +GGG S
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSG---SGGGSGGGY----GGGSGGGHSGGSGGGHS 551
Query: 120 SSRLHSY--SSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGG 164
+Y S S S GG S SRGG G S G+ GG
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGG 598
Score = 50.4 bits (119), Expect = 8e-06
Identities = 34/106 (32%), Positives = 34/106 (32%)
Query: 61 GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSS 120
G S SRG GG GS G S G G G S S G Y G GS
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566
Query: 121 SRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
Y S GG S GG S G A G G G
Sbjct: 567 GSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG 612
Score = 47.4 bits (111), Expect = 7e-05
Identities = 38/90 (42%), Positives = 40/90 (44%), Gaps = 9/90 (10%)
Query: 76 GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSS 135
GSGGS SS + S GG SS GG G G S +SY S
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG-----GGS 77
Query: 136 GGGESRSSSRGG-GGESRSSGAASSAPGGG 164
GGG S SS GG GG SR G AS GGG
Sbjct: 78 GGGFSASSLGGGFGGGSRGFGGAS---GGG 104
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/110 (36%), Positives = 45/110 (40%), Gaps = 5/110 (4%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
GG +S S GG GG SSS + GGGS R S G S +GGG S
Sbjct: 25 GGSIRSSYSRFSSSGGGGGGGRFSSS--SGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFS 82
Query: 120 SSRL---HSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
+S L S +SGGG S S GGG S G G G G
Sbjct: 83 ASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFG 132
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/101 (41%), Positives = 47/101 (46%), Gaps = 13/101 (12%)
Query: 58 SRGGEDSTSRGERSKKLGG--SGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTG 115
S GG S G S GG SGGS G+ G + SGGGS + S SRGGS G
Sbjct: 530 SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG-YGGGSGSRGGSGG-SHG 587
Query: 116 GGSSSSRLHSYSSPSTKNSSGGGESRSSSRG--GGGESRSS 154
GGS + S GGGE S S G GGG +SS
Sbjct: 588 GGSG-------FGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/110 (34%), Positives = 42/110 (38%), Gaps = 11/110 (10%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGS-NGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGG 116
S GG + G GGSGG +G S G G G + S GG GG
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGG----NYGGGSGSGGGSGGGYGG 574
Query: 117 GSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
GS S S S SG G S GGG E+ SG GGG G
Sbjct: 575 GSGS---RGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGY---GGGSG 618
Score = 41.6 bits (96), Expect = 0.004
Identities = 32/91 (35%), Positives = 39/91 (42%), Gaps = 13/91 (14%)
Query: 83 SSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRS 142
SSS + SGGG L S SR +GGG R S+ + GGG SR
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRF------SSSSGYGGGSSRV 60
Query: 143 SSRGGGGE-------SRSSGAASSAPGGGDG 166
RGGGG G ++S+ GGG G
Sbjct: 61 CGRGGGGSFGYSYGGGSGGGFSASSLGGGFG 91
Score = 39.7 bits (91), Expect = 0.014
Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 10/97 (10%)
Query: 71 SKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPS 130
S L SGG G G GGS RS + SSS GG GGG S Y S
Sbjct: 8 SSYLSRSGGGGGGGLGS----GGSIRSSYSRFSSSGGG------GGGGRFSSSSGYGGGS 57
Query: 131 TKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGA 167
++ GG GGG A+S G G G+
Sbjct: 58 SRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGS 94
Score = 38.9 bits (89), Expect = 0.024
Identities = 33/106 (31%), Positives = 38/106 (35%), Gaps = 19/106 (17%)
Query: 64 STSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRL 123
S+ G + S G G SS GG GGS Y GGGS
Sbjct: 37 SSGGGGGGGRFSSSSGYGGGSSRVCGRGG--------------GGSFGYSYGGGSGG--- 79
Query: 124 HSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEY 169
+S+ S GGG GGG S SSG GGG G +
Sbjct: 80 -GFSASSLGGGFGGGSRGFGGASGGGYS-SSGGFGGGFGGGSGGGF 123
Score = 38.1 bits (87), Expect = 0.041
Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 97 SLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRG-GGGESR--- 152
S +L +S GG G GS S SYS S+ GGG SSS G GGG SR
Sbjct: 8 SSYLSRSGGGGGG-----GLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCG 62
Query: 153 --SSGAASSAPGGGDGAEY 169
G+ + GGG G +
Sbjct: 63 RGGGGSFGYSYGGGSGGGF 81
Score = 30.4 bits (67), Expect = 8.5
Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 13/88 (14%)
Query: 126 YSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEA 185
+SS S GGG G GG RSS + S+ GGG G G S
Sbjct: 6 FSSSYLSRSGGGG---GGGLGSGGSIRSSYSRFSSSGGGGGG----------GRFSSSSG 52
Query: 186 VEDGLFHEFKRFGDVSVKISHLSGSGSG 213
G R G S S+ GSG G
Sbjct: 53 YGGGSSRVCGRGGGGSFGYSYGGGSGGG 80
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/262 (25%), Positives = 102/262 (38%), Gaps = 40/262 (15%)
Query: 267 PPSASVVGASVGGHRHPPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRD 326
PP A+V G G + PG GG + PGG G G P P+
Sbjct: 186 PPPAAVPGPGPGP-KQGPGPGGPKGGKMPGGPKPG-----------GGPGLSTPGGHPKP 233
Query: 327 LERERDYPFYERV-RPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRT---------- 375
R P R P Y + G G R ++IS + +AN +
Sbjct: 234 PHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTY 293
Query: 376 -----LFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRA 430
LF+GNL +TE + +R F ++G EV I + +G +GF+K E+ ++ A
Sbjct: 294 TQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINK-GKG----FGFIKLESRALAEIA 348
Query: 431 KLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTI-----D 485
K + + +++ + AT L V L P+V L F +FG I D
Sbjct: 349 KAELDDTPMRGRQLRVRF--ATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDD 406
Query: 486 YRKGDSWAYIQYESLDAAHAAW 507
+ +++ S AA A+
Sbjct: 407 RGRSTGKGIVEFASKPAARKAF 428
Score = 36.2 bits (82), Expect = 0.15
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 7/120 (5%)
Query: 439 IIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYE 498
++R P + Y T RL+VG L + R F ++G + KG + +I+ E
Sbjct: 284 LLRRPGEKTY---TQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLE 340
Query: 499 SLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAP 558
S A A + P+ G R+LRV FA H P EL+ +AF P
Sbjct: 341 SRALAEIAKAELDDTPMRG--RQLRVRFA--THAAALSVRNLSPYVSNELLEEAFSQFGP 396
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 54.7 bits (130), Expect = 4e-07
Identities = 65/226 (28%), Positives = 91/226 (40%), Gaps = 16/226 (7%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREY------- 112
GG + + + GGSGGS SSSG G GS R D+ SS G S+E
Sbjct: 160 GGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRR 219
Query: 113 -DTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKT 171
GGS +S+ S S S + + +S SSS GG +S+ A SS+ + K
Sbjct: 220 DGQRGGSEASKSRSRHSHSGEERAEVAKSGSSS-SSGGRRKSASATSSSSSSRKDRDSKA 278
Query: 172 LKISELGSQLSDEAVED--GLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDAR 229
+ S+ A ++ + E K + LS G D+ + V+ R + R
Sbjct: 279 HRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDD--SPVSHRASQSLR 336
Query: 230 AAKH---ARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSASV 272
+ K A G Y R L SRRRS S +Y V
Sbjct: 337 SRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDV 382
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/314 (23%), Positives = 108/314 (34%), Gaps = 33/314 (10%)
Query: 54 KAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYD 113
+ KR GG RG R+ G + K RR L + GG
Sbjct: 94 RGKRRAGGRQKRRRGPRA----------GQEAEK-------RRVFSLPQPQQDGGGGASS 136
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGG----GDGAEY 169
GG + SS S + GG S +++ G + SG + ++ G G+G+E
Sbjct: 137 GGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSER 196
Query: 170 KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDAR 229
+ + S S E + + +R G + K S S SG+ER +
Sbjct: 197 RPRRDRRSSSGRSKERHREHRRRDGQRGGSEASK-SRSRHSHSGEERAEVAKSGSSSSSG 255
Query: 230 AAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSA-SVVGASVGGHRHPPGGGG 288
+ + K R R++S + PPSA + + P
Sbjct: 256 GRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE----PPSAYKEPPKAYREDKTEPKAYR 311
Query: 289 GQRSLSP-GGAALGYRDYRLQQLALGRLPPPP----PPPLPRDLERERDYPFYERVRPAY 343
+RSLSP GG +R Q R P P P R L R P+ R P+Y
Sbjct: 312 RRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS-PYSRRRSPSY 370
Query: 344 SLEPRVGAGAGAAP 357
S G +P
Sbjct: 371 SRHSSYERGGDVSP 384
Score = 40.8 bits (94), Expect = 0.006
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 46 KGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRS--LHLDKS 103
+G ER P + +RS G E ++ G GGS S S S G R+ S
Sbjct: 192 EGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSS 251
Query: 104 SSRGGSREYDTGGGSSSS 121
SS GG R+ + SSSS
Sbjct: 252 SSSGGRRKSASATSSSSS 269
Score = 38.9 bits (89), Expect = 0.024
Identities = 46/176 (26%), Positives = 68/176 (38%), Gaps = 14/176 (7%)
Query: 616 RRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSP 675
+RR S R R DR S R + R R G R E+ + R RH +R+
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRG---GSEASKSRSRHSHSGEERAE 244
Query: 676 ELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTA 735
S + +S+ S +DR +S+ SA E + +R
Sbjct: 245 VAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK 304
Query: 736 PTEGK--------SPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPK 783
TE K SPL D S S ++ + S+ KSPS GG++P + P+
Sbjct: 305 -TEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR-KSPSPA-GGGSSPYSRRLPR 357
Score = 37.7 bits (86), Expect = 0.053
Identities = 56/247 (22%), Positives = 82/247 (33%), Gaps = 19/247 (7%)
Query: 582 PDSDWVPPPPPVRERSTRTAA-TSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSR---D 637
P S + PP RE T A + PL D + R PS
Sbjct: 289 PPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGS 348
Query: 638 QPRKRRLPEESGGRHLDRSPESDR----PRKRHCAPSPDRSPELSSSRDRYNSDNDRSSR 693
P RRLP RSP R R +PSP S SR Y+ RS +
Sbjct: 349 SPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGK 408
Query: 694 LLLERPSPIRDRRGSLEKSQGDKRDR-----------KNSASAERDRKHRTTAPTEGKSP 742
P R R R R K+S +AE ++ + A ++
Sbjct: 409 SRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAA 468
Query: 743 LKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSN 802
+ A + ++K + S G T ASAS + + ++++ PS+
Sbjct: 469 EAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSS 528
Query: 803 MHLLQGD 809
L+ D
Sbjct: 529 GGTLKND 535
Score = 32.7 bits (73), Expect = 1.7
Identities = 45/178 (25%), Positives = 67/178 (37%), Gaps = 26/178 (14%)
Query: 2 RTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGG 61
R G + PRR R +S+GR + R + RR G E S +++ S G
Sbjct: 190 RGEGSERRPRRDRR---------SSSGRSKERHR-EHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 62 EDSTSRGERSKKLGGSGGSNG--SSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
E+ R E +K G S S G S+ T S SR+ D + R ++ +
Sbjct: 240 EE---RAEVAKS-GSSSSSGGRRKSASATSSSSSSRKD--RDSKAHRSRTKSSKEPPSAY 293
Query: 120 SSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASS--------APGGGDGAEY 169
+Y T+ + S GG +S S AS +P GG + Y
Sbjct: 294 KEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPY 351
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 54.7 bits (130), Expect = 4e-07
Identities = 65/226 (28%), Positives = 91/226 (40%), Gaps = 16/226 (7%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREY------- 112
GG + + + GGSGGS SSSG G GS R D+ SS G S+E
Sbjct: 160 GGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRR 219
Query: 113 -DTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKT 171
GGS +S+ S S S + + +S SSS GG +S+ A SS+ + K
Sbjct: 220 DGQRGGSEASKSRSRHSHSGEERAEVAKSGSSS-SSGGRRKSASATSSSSSSRKDRDSKA 278
Query: 172 LKISELGSQLSDEAVED--GLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDAR 229
+ S+ A ++ + E K + LS G D+ + V+ R + R
Sbjct: 279 HRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDD--SPVSHRASQSLR 336
Query: 230 AAKH---ARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSASV 272
+ K A G Y R L SRRRS S +Y V
Sbjct: 337 SRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDV 382
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/314 (23%), Positives = 108/314 (34%), Gaps = 33/314 (10%)
Query: 54 KAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYD 113
+ KR GG RG R+ G + K RR L + GG
Sbjct: 94 RGKRRAGGRQKRRRGPRA----------GQEAEK-------RRVFSLPQPQQDGGGGASS 136
Query: 114 TGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGG----GDGAEY 169
GG + SS S + GG S +++ G + SG + ++ G G+G+E
Sbjct: 137 GGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSER 196
Query: 170 KTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDAR 229
+ + S S E + + +R G + K S S SG+ER +
Sbjct: 197 RPRRDRRSSSGRSKERHREHRRRDGQRGGSEASK-SRSRHSHSGEERAEVAKSGSSSSSG 255
Query: 230 AAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSA-SVVGASVGGHRHPPGGGG 288
+ + K R R++S + PPSA + + P
Sbjct: 256 GRRKSASATSSSSSSRKDRDSKAHRSRTKSSKE----PPSAYKEPPKAYREDKTEPKAYR 311
Query: 289 GQRSLSP-GGAALGYRDYRLQQLALGRLPPPP----PPPLPRDLERERDYPFYERVRPAY 343
+RSLSP GG +R Q R P P P R L R P+ R P+Y
Sbjct: 312 RRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS-PYSRRRSPSY 370
Query: 344 SLEPRVGAGAGAAP 357
S G +P
Sbjct: 371 SRHSSYERGGDVSP 384
Score = 40.8 bits (94), Expect = 0.006
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 46 KGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRS--LHLDKS 103
+G ER P + +RS G E ++ G GGS S S S G R+ S
Sbjct: 192 EGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSS 251
Query: 104 SSRGGSREYDTGGGSSSS 121
SS GG R+ + SSSS
Sbjct: 252 SSSGGRRKSASATSSSSS 269
Score = 38.9 bits (89), Expect = 0.024
Identities = 46/176 (26%), Positives = 68/176 (38%), Gaps = 14/176 (7%)
Query: 616 RRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSP 675
+RR S R R DR S R + R R G R E+ + R RH +R+
Sbjct: 188 QRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRG---GSEASKSRSRHSHSGEERAE 244
Query: 676 ELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTA 735
S + +S+ S +DR +S+ SA E + +R
Sbjct: 245 VAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK 304
Query: 736 PTEGK--------SPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPK 783
TE K SPL D S S ++ + S+ KSPS GG++P + P+
Sbjct: 305 -TEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR-KSPSPA-GGGSSPYSRRLPR 357
Score = 37.7 bits (86), Expect = 0.053
Identities = 56/247 (22%), Positives = 82/247 (33%), Gaps = 19/247 (7%)
Query: 582 PDSDWVPPPPPVRERSTRTAA-TSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSR---D 637
P S + PP RE T A + PL D + R PS
Sbjct: 289 PPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGS 348
Query: 638 QPRKRRLPEESGGRHLDRSPESDR----PRKRHCAPSPDRSPELSSSRDRYNSDNDRSSR 693
P RRLP RSP R R +PSP S SR Y+ RS +
Sbjct: 349 SPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGK 408
Query: 694 LLLERPSPIRDRRGSLEKSQGDKRDR-----------KNSASAERDRKHRTTAPTEGKSP 742
P R R R R K+S +AE ++ + A ++
Sbjct: 409 SRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAA 468
Query: 743 LKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSN 802
+ A + ++K + S G T ASAS + + ++++ PS+
Sbjct: 469 EAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSS 528
Query: 803 MHLLQGD 809
L+ D
Sbjct: 529 GGTLKND 535
Score = 32.7 bits (73), Expect = 1.7
Identities = 45/178 (25%), Positives = 67/178 (37%), Gaps = 26/178 (14%)
Query: 2 RTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGG 61
R G + PRR R +S+GR + R + RR G E S +++ S G
Sbjct: 190 RGEGSERRPRRDRR---------SSSGRSKERHR-EHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 62 EDSTSRGERSKKLGGSGGSNG--SSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
E+ R E +K G S S G S+ T S SR+ D + R ++ +
Sbjct: 240 EE---RAEVAKS-GSSSSSGGRRKSASATSSSSSSRKD--RDSKAHRSRTKSSKEPPSAY 293
Query: 120 SSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASS--------APGGGDGAEY 169
+Y T+ + S GG +S S AS +P GG + Y
Sbjct: 294 KEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPY 351
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 54.3 bits (129), Expect = 5e-07
Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 626 DRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYN 685
D+ DRD S+++ ++ R P+ R DR + RKRH S DR S SR R
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRH--RSRDRRRGGSRSRSR-- 62
Query: 686 SDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKK 745
RS ER R+R ++++ D+ K+ ++DRK + +P GK +
Sbjct: 63 ---SRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSR 119
Query: 746 EDR 748
+DR
Sbjct: 120 KDR 122
Score = 38.5 bits (88), Expect = 0.031
Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 20/183 (10%)
Query: 595 ERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGG---R 651
++ R A+ S + + DR RD RDR + P S+D+ R R GG R
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERD-----RDRDRKSSP-SKDRKRHRSRDRRRGGSRSR 60
Query: 652 HLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSS----RLLLERPSPIRDRRG 707
RS ++R R+ + E RDR D DR R + S + RG
Sbjct: 61 SRSRSKSAERERRH-------KERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRG 113
Query: 708 SLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPS 767
KS+ D+ +K+ D+K + + + KK+ + A + ++ ++ +
Sbjct: 114 KDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEA 173
Query: 768 QKQ 770
K+
Sbjct: 174 LKR 176
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 53.9 bits (128), Expect = 7e-07
Identities = 42/104 (40%), Positives = 43/104 (41%), Gaps = 15/104 (14%)
Query: 64 STSRGERSKKLGG-SGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSR 122
S GE S GG GGS G G SGGGS H GGS GGGSS
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGH---GGGHGGSSGGGYGGGSSGG- 506
Query: 123 LHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
SSGGG SS GG G S S G + GGG G
Sbjct: 507 ----------GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGG 540
Score = 53.5 bits (127), Expect = 9e-07
Identities = 50/143 (34%), Positives = 64/143 (44%), Gaps = 11/143 (7%)
Query: 29 RRVTQLRGDDLRRPATMKGKERSPVKAKRSR-GGEDSTSRGERSKKLGGS--GGSNGSSS 85
R T+ + + ++ +K + + ++ RS GE S+ G R GGS GG G SS
Sbjct: 422 RAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRG---GGSFGGGYGGGSS 478
Query: 86 GKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTK--NSSGGGESRSS 143
G SGGG SS GG +GGGSS SS +SSGG SS
Sbjct: 479 GGGSSGGGHGGG---HGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSS 535
Query: 144 SRGGGGESRSSGAASSAPGGGDG 166
GGGG S S+ GGG G
Sbjct: 536 GGGGGGYGGGSSGGGSSSGGGYG 558
Score = 51.6 bits (122), Expect = 4e-06
Identities = 42/109 (38%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSS--RGGSREYDTGGG 117
GG S GG GGS+G G SGGGS + SSS GGS GGG
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533
Query: 118 SSSSRLHSYSSPSTK--NSSGGGESRSSSRGGGGESRSSGAASSAPGGG 164
SS Y S+ +SSGGG SS GG +S SSG+ + G
Sbjct: 534 SSGGGGGGYGGGSSGGGSSSGGGYGGGSS-SGGHKSSSSGSVGESSSKG 581
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/109 (38%), Positives = 43/109 (39%), Gaps = 15/109 (13%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S GG G S G G S G SSG GG S S GGS GGG
Sbjct: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS--------SGGHGGSSSGGYGGG 533
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
SS Y SSGGG SSS GG G SSG S+ G G
Sbjct: 534 SSGGGGGGYGG----GSSGGG---SSSGGGYGGGSSSGGHKSSSSGSVG 575
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/106 (34%), Positives = 39/106 (36%), Gaps = 13/106 (12%)
Query: 58 SRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGG 117
S GG S S G GGS+G G GGGS R + SSS GGS GGG
Sbjct: 48 SSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSY--GSSSFGGSYGGSFGGG 105
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGG 163
S S GGG GGGG G GG
Sbjct: 106 SFGG-----------GSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140
Score = 40.8 bits (94), Expect = 0.006
Identities = 41/115 (35%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGS- 118
GG S+ R SK G G S+G SG + S G S S GG + GGGS
Sbjct: 28 GGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGF--GGGSF 85
Query: 119 -----SSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAE 168
SSS SY S GGG S GGGG G GGG G +
Sbjct: 86 RGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG--FGGGGFGGGFGGGFGGD 138
Score = 39.3 bits (90), Expect = 0.018
Identities = 34/106 (32%), Positives = 42/106 (39%), Gaps = 9/106 (8%)
Query: 64 STSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRL 123
S+S+ S + GG GG G G GG S + K S GG + +GG S S
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGG----GGVSSLRISSSKGSLGGG---FSSGGFSGGSFS 58
Query: 124 HSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEY 169
S S GG GGG S G SS+ GG G +
Sbjct: 59 RGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYG--SSSFGGSYGGSF 102
Score = 38.9 bits (89), Expect = 0.024
Identities = 28/72 (38%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 96 RSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG 155
RSL + SS GG R GGGS SS + G G S GGG SSG
Sbjct: 450 RSLLEGEGSSGGGGR----GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
Query: 156 AASSAPGGGDGA 167
SS G G G+
Sbjct: 506 GGSSGGGYGGGS 517
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 53.9 bits (128), Expect = 7e-07
Identities = 60/255 (23%), Positives = 95/255 (37%), Gaps = 40/255 (15%)
Query: 366 PEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPS-RGQTSTYGFLKFENL 424
P ++ + T+++G LD V+E L F + G + + + GQ YGF++F +
Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
Query: 425 DMSHRAKLAMSGKIIIRNPIKIGYGKATPTT-----RLWVGGLGPWVPLAALAREFDRFG 479
+ + A M+ + PI++ A +++G L P + L F FG
Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFG 124
Query: 480 TI-------RTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHR 532
I R D +A+I + S DA+ AA M G
Sbjct: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNG-------------------- 164
Query: 533 YQQQYLQPLPLT-HYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPP 591
QYL P+T Y D+ G R PL DR L+ D+ PPPP
Sbjct: 165 ---QYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADA---PPPP 218
Query: 592 PVRERSTRTAATSVP 606
+ + +P
Sbjct: 219 SAPNPVVSSLGSGLP 233
Score = 32.0 bits (71), Expect = 2.9
Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 12/69 (17%)
Query: 267 PPSASVVGASVGGHRH------PPGG----GGGQRSLSPGGA-ALGYRDYRLQQLALGRL 315
PPSA GA GH H PPGG G Q L+ G LG+ + + G+
Sbjct: 275 PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGH-PHAGPPGSGGQP 333
Query: 316 PPPPPPPLP 324
PP PPP +P
Sbjct: 334 PPRPPPGMP 342
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 53.9 bits (128), Expect = 7e-07
Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 7/141 (4%)
Query: 635 SRDQPRKRRLPEESGGRHLDRSPESDRPRK----RHCAPSPDRSPELSSSRDRYNSDNDR 690
SR ++ SG R RSP R ++ R + DR E S SRD+ S +
Sbjct: 5 SRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRD 64
Query: 691 SSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSD 750
RL R S R+R S E+ + RDR+ S S R R+ R+++P + RS
Sbjct: 65 RKRL---RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 751 GSAPSTSTASSKLKSPSQKQD 771
++ K K K+D
Sbjct: 122 EKTDGGESSKEKKKDKDDKED 142
Score = 38.9 bits (89), Expect = 0.024
Identities = 37/110 (33%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 46 KGKERSPVKAKRSRGGEDSTSRG-ERSKKLGGSGGSNGSSSGKTDSGGGSR-RSLHLDKS 103
+ + RSP KRS+ G+D SR +R ++ S + S D R RS D+S
Sbjct: 21 RSRSRSP-SDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79
Query: 104 SSRGGSREYDTGGGSSSSR--LHSYSSPSTKNSSGGGESRSSSRGGGGES 151
R SR D S SR SSP K+ SRS + GGES
Sbjct: 80 RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGES 129
Score = 35.4 bits (80), Expect = 0.26
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 27/135 (20%)
Query: 610 PLDSLDRRRD---GWSLDRDRG-------DRDLPSSRDQPRKRRLPEESGGRHLDRSPES 659
P D +R D S DRDR D+ SRD+ R RR RS E
Sbjct: 27 PSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR----------SRSRER 76
Query: 660 DRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQG--DKR 717
DR R+R + S DR S SR R + + + + +R S EK+ G +
Sbjct: 77 DRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGN-----KSKKTENRSRSKEKTDGGESSK 131
Query: 718 DRKNSASAERDRKHR 732
++K + D K +
Sbjct: 132 EKKKDKDDKEDEKEK 146
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 53.5 bits (127), Expect = 9e-07
Identities = 47/141 (33%), Positives = 54/141 (38%), Gaps = 16/141 (11%)
Query: 32 TQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSG------GSNGSSS 85
T L G++ R M G+ V S + G R GG G GS G S
Sbjct: 484 TLLEGEESR----MSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY 539
Query: 86 GKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSR 145
G GGG R S SS G Y +GGG SY S SS GG S
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH--GSYGS----GSSSGGYRGGSGG 593
Query: 146 GGGGESRSSGAASSAPGGGDG 166
GGGG S G+ + GG G
Sbjct: 594 GGGGSSGGRGSGGGSSGGSIG 614
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/89 (39%), Positives = 36/89 (40%), Gaps = 2/89 (2%)
Query: 76 GSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSS 135
GSGG G G SGG S S S GG G GSSS S SS
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSS 599
Query: 136 GGGESRSSSRGG--GGESRSSGAASSAPG 162
GG S S GG GG SSG S+ G
Sbjct: 600 GGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628
Score = 45.4 bits (106), Expect = 3e-04
Identities = 38/100 (38%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSS 119
GG RG G G S GS G SGGG SS GG R GGG
Sbjct: 542 GGGGGGGRGS----YGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGG 597
Query: 120 SSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASS 159
SS S+ S GG R SS GG +SSG +SS
Sbjct: 598 SSGGRGSGGGSSGGSIGG---RGSSSGG---VKSSGGSSS 631
Score = 37.4 bits (85), Expect = 0.069
Identities = 38/120 (31%), Positives = 42/120 (35%), Gaps = 23/120 (19%)
Query: 56 KRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSS------RGGS 109
+RS GG G R GG GGS G+ G GSR ++L S S RGG
Sbjct: 37 RRSGGG------GGRFSSCGGGGGSFGAGGGF-----GSRSLVNLGGSKSISISVARGGG 85
Query: 110 REYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEY 169
R GGG GGG GGG SG GG G Y
Sbjct: 86 RGSGFGGGYGGGGFGG------GGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGY 139
Score = 37.4 bits (85), Expect = 0.069
Identities = 30/74 (40%), Positives = 32/74 (43%), Gaps = 12/74 (16%)
Query: 61 GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSS 120
G S+S G R GGSGG G SSG SGGGS S G R +GG SS
Sbjct: 579 GSGSSSGGYR----GGSGGGGGGSSGGRGSGGGS--------SGGSIGGRGSSSGGVKSS 626
Query: 121 SRLHSYSSPSTKNS 134
S ST S
Sbjct: 627 GGSSSVKFVSTTYS 640
Score = 37.0 bits (84), Expect = 0.090
Identities = 40/131 (30%), Positives = 46/131 (35%), Gaps = 28/131 (21%)
Query: 57 RSRGGEDSTSRG----------ERSKKLGGSGG---SNGSSSGKTDSGG--GSRRSLHLD 101
RS GG S S G +++ GG GG S G G +GG GSR ++L
Sbjct: 12 RSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLG 71
Query: 102 KSSS------RGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG 155
S S RGG R GGG GGG GGGG
Sbjct: 72 GSKSISISVARGGGRGSGFGGGYGGGGFGG-------GGFGGGGFGGGGIGGGGFGGFGS 124
Query: 156 AASSAPGGGDG 166
GGG G
Sbjct: 125 GGGGFGGGGFG 135
Score = 33.9 bits (76), Expect = 0.76
Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 60 GGEDSTSRGERSKKLGGSGGSN-GSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGS 118
GG S G S G G G SSG SGGGS + SS GG + + GGS
Sbjct: 573 GGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVK---SSGGS 629
Query: 119 SSSRLHS 125
SS + S
Sbjct: 630 SSVKFVS 636
Score = 30.8 bits (68), Expect = 6.5
Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 12/59 (20%)
Query: 104 SSRGGSREYDTGGGSSSS-------RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG 155
SSR G Y +GGG SS + + SS + ++ GGG R SS GGGG S +G
Sbjct: 6 SSRSG---YRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGG--RFSSCGGGGGSFGAG 59
>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
[Homo sapiens]
Length = 285
Score = 53.5 bits (127), Expect = 9e-07
Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 13/145 (8%)
Query: 352 GAGAAP------FREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDI 405
GA AAP E D+I+ ++ +F+G L ++ DL+ F +FG + + I
Sbjct: 42 GATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTI 101
Query: 406 KR-PSRGQTSTYGFLKFENL----DMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVG 460
K P+ G++ +GF+ F++ + + + + G++I +P K K P +++VG
Sbjct: 102 KMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVI--DPKKAMAMKKDPVKKIFVG 159
Query: 461 GLGPWVPLAALAREFDRFGTIRTID 485
GL P + F FG I I+
Sbjct: 160 GLNPEATEEKIREYFGEFGEIEAIE 184
Score = 30.8 bits (68), Expect = 6.5
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSS-GKTDSGGGSRRS 97
GG + +RG R GG GG GS++ GK+ GG + +
Sbjct: 243 GGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNN 281
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 53.5 bits (127), Expect = 9e-07
Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 13/145 (8%)
Query: 352 GAGAAP------FREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDI 405
GA AAP E D+I+ ++ +F+G L ++ DL+ F +FG + + I
Sbjct: 42 GATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTI 101
Query: 406 KR-PSRGQTSTYGFLKFENL----DMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVG 460
K P+ G++ +GF+ F++ + + + + G++I +P K K P +++VG
Sbjct: 102 KMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVI--DPKKAMAMKKDPVKKIFVG 159
Query: 461 GLGPWVPLAALAREFDRFGTIRTID 485
GL P + F FG I I+
Sbjct: 160 GLNPEATEEKIREYFGEFGEIEAIE 184
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 53.1 bits (126), Expect = 1e-06
Identities = 102/447 (22%), Positives = 164/447 (36%), Gaps = 73/447 (16%)
Query: 376 LFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMS 435
+++G L E D+ R F +G I EVD+K + YGF++F++L + A ++
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK-------NGYGFVEFDDLRDADDAVYELN 56
Query: 436 GK------III---RNPIKIG------------------YGKATPTT-RLWVGGLGPWVP 467
GK +I+ R P + G YG T T RL V L
Sbjct: 57 GKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCS 116
Query: 468 LAALAREFDRFGTIRTIDYRKG-DSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDF 526
L + G + D KG + I++ S A + G + G R++R+
Sbjct: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNG--RKIRLVE 174
Query: 527 ADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDW 586
R ++ Y + + H R ++ R R R
Sbjct: 175 DKPGSRRRRSYSRS---RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 587 VPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPE 646
R RS + + S P R R S + R S+DQ ++
Sbjct: 232 SRSRSQSRSRSKKEKSRS-----PSKEKSRSRSH-SAGKSRS-----KSKDQAEEKIQNN 280
Query: 647 ESGGRHLDRSPESDRPRKRHCAPSPDRSPEL----SSSRDRYNSDNDRSSRLLLERPSPI 702
++ G+ RSP + + + + S +R E S SR R + R SR
Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 703 RDRRGSLEKSQGDKRDRKNSAS-----------AERDRKHRTTAPTEGKSPLKKE----D 747
R R S KS+ ++ RK S +ER RK + ++ S KK+ D
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 748 RSDGSAPSTSTASSK--LKSPSQKQDG 772
RS +PS S + + KS S +++G
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREG 427
Score = 48.5 bits (114), Expect = 3e-05
Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 11/156 (7%)
Query: 618 RDGWSLDRDRG-----DRDLPSSRDQPR-KRRLPEESGGRHLDRSPESDRPRKRHCAPSP 671
R S R +G R S+D+ + ++R EES R RS +S+R RKR
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS-KSERSRKR----GS 382
Query: 672 DRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKH 731
R + SS+ + D DRS R E SQ + R +A ++ +
Sbjct: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
Query: 732 RTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPS 767
R+ + ++ K L E RS + S + + SK +S S
Sbjct: 443 RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
Score = 48.1 bits (113), Expect = 4e-05
Identities = 78/336 (23%), Positives = 122/336 (36%), Gaps = 52/336 (15%)
Query: 456 RLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPL 515
R+++G L + R F +G I +D + G + +++++ L A A + G L
Sbjct: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNG--YGFVEFDDLRDADDAVYELNGKDL 60
Query: 516 GGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLL--- 572
G R+ V+ A R Y +G+R R RD+ P
Sbjct: 61 CG--ERVIVEHARGPRRDGS----------YGSGRSGYGYR-----RSGRDKYGPPTRTE 103
Query: 573 YRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWS-----LDRDR 627
YR +L W +R+ T A + R+ +G D R
Sbjct: 104 YRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKG--------RKNEGVIEFVSYSDMKR 155
Query: 628 GDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSD 687
L + RK RL E+ G RS R R S RS SR R S
Sbjct: 156 ALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSR----SRSRSRHSRKSRSRSGSS 211
Query: 688 NDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKED 747
S+ S R R S +SQ R +K + + K R+ + + GKS K +D
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 748 RSD-------------GSAPSTSTASSKLKSPSQKQ 770
+++ +PS + SK +S SQ++
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307
Score = 40.8 bits (94), Expect = 0.006
Identities = 37/116 (31%), Positives = 50/116 (43%), Gaps = 18/116 (15%)
Query: 46 KGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSS 105
KG++RS + SR S S+ ERS+K G S SS K ++ D+S S
Sbjct: 355 KGRKRS---REESRSRSRSRSKSERSRKRGSKRDSKAGSSKK-------KKKEDTDRSQS 404
Query: 106 RGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAP 161
R SR S R H+ S S + G GES ++ SRS + S P
Sbjct: 405 RSPSRSV------SKEREHAKSESSQR--EGRGESENAGTNQETRSRSRSNSKSKP 452
Score = 40.4 bits (93), Expect = 0.008
Identities = 41/144 (28%), Positives = 57/144 (39%), Gaps = 15/144 (10%)
Query: 40 RRPATMKGKERSPVKAKRSRGGED---STSRGE-----------RSKKLGGSGGSNGSSS 85
R P+ K K +S +++ R E+ S SRG RS+ GGS + S S
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 86 GKTDSGGGSRRSLHLDKSSSRGGSR-EYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSS 144
D G +RS +S SR S+ E GS S K + +SRS S
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
Query: 145 RGGGGESRSSGAASSAPGGGDGAE 168
R E + + SS G +E
Sbjct: 409 RSVSKEREHAKSESSQREGRGESE 432
Score = 39.3 bits (90), Expect = 0.018
Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 25/151 (16%)
Query: 32 TQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSG 91
T++ G +R G R RSR S SR S+K GS+ SS K+
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRR-SYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS--- 218
Query: 92 GGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGES 151
+S SR GSR S SR S S +K S+ SR S
Sbjct: 219 ----------RSRSRSGSR------SRSKSRSRSQSRSRSKKEKSRSPSKEKSR-----S 257
Query: 152 RSSGAASSAPGGGDGAEYKTLKISELGSQLS 182
RS A S D AE K +G S
Sbjct: 258 RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Score = 38.1 bits (87), Expect = 0.041
Identities = 47/173 (27%), Positives = 60/173 (34%), Gaps = 28/173 (16%)
Query: 26 SAGRRVTQLRGDDLRRPATMKGKERSPVKAK-----RSRGGEDSTSRGERSKKLG----- 75
S R ++ R R + K K RSP K K S G S S+ + +K+
Sbjct: 224 SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 76 GSGGSNGSSSGKTDSGGGSR---------------RSLHLDKSSSRGGSREYDTGGGSSS 120
G S S K+ S SR R +KS + SR GG S
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 121 SRLHSYSSPSTKNSSGGGE---SRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
SR S S K E SRS SR SR G+ + G + K
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 52.8 bits (125), Expect = 2e-06
Identities = 64/258 (24%), Positives = 96/258 (37%), Gaps = 32/258 (12%)
Query: 60 GGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSL-HLDKSS-SRGGSREYDTGGG 117
GG + G+ + GGS G + SGGG D+ RGGS GGG
Sbjct: 170 GGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGG 229
Query: 118 SSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG---AASSAPGGGDGAEYKTLKI 174
+R P + GG GG ++ G S D ++ T+ +
Sbjct: 230 GGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFV 289
Query: 175 SELGSQLSDEAVED-----GLFHEFKRFGD--VSVKISHLSGSGSGDERVAFVNFRRPED 227
LG ++ E+V D G+ K+ G +++ +G G+ A V+F P
Sbjct: 290 QGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGE---ATVSFDDPPS 346
Query: 228 ARAAKHARGRLVLYDRPLKIEAVYVSRR-------------RSR-SPLDKDTYPPSASVV 273
A+AA P+K+ + +RR R R P+ + Y S
Sbjct: 347 AKAAIDWFDGKEFSGNPIKVS--FATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS-G 403
Query: 274 GASVGGHRHPPGGGGGQR 291
G GG GGGGGQ+
Sbjct: 404 GGGRGGFPSGGGGGGGQQ 421
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 71 SKKLGGSGGSNGSSS-GKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSP 129
S G G S+ SSS G+ SG S++ + + S G + Y+ G ++ SS
Sbjct: 107 SSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSG 166
Query: 130 STKNSSGG---GESRSSSRGGGGESRSSGAASSAPGGGDG 166
GG G+ +SS GGG G + GGG G
Sbjct: 167 GGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG 206
Score = 36.2 bits (82), Expect = 0.15
Identities = 37/137 (27%), Positives = 50/137 (36%), Gaps = 19/137 (13%)
Query: 42 PATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLD 101
P++ G S ++ S G+ + + GG S G G +++ +
Sbjct: 106 PSSTSGSYGS--SSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQY-- 161
Query: 102 KSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSG------ 155
SSS GG GGG + SS S+ SGGG GGGG S G
Sbjct: 162 NSSSGGGG-----GGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGG-SGGYGQQDRGG 215
Query: 156 ---AASSAPGGGDGAEY 169
S GGG G Y
Sbjct: 216 RGRGGSGGGGGGGGGGY 232
Score = 32.3 bits (72), Expect = 2.2
Identities = 31/104 (29%), Positives = 42/104 (40%), Gaps = 10/104 (9%)
Query: 61 GEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGG-GSS 119
G+ S S +S G G S+ SS G++ + G +S S TGG GSS
Sbjct: 34 GQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGS---------TGGYGSS 84
Query: 120 SSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGG 163
S SY S+ G + SS+ G G S S + G
Sbjct: 85 QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128
Score = 30.4 bits (67), Expect = 8.5
Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 12/93 (12%)
Query: 80 SNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGE 139
S G+ + G + S + S G S+ DT G SS YSS ++G G
Sbjct: 13 SYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSS----YSSYGQSQNTGYGT 68
Query: 140 SRS----SSRGGGGESRSS----GAASSAPGGG 164
+ S GG G S+SS G SS PG G
Sbjct: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYG 101
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 52.4 bits (124), Expect = 2e-06
Identities = 88/397 (22%), Positives = 147/397 (37%), Gaps = 67/397 (16%)
Query: 376 LFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMS 435
+++G L V E D++R F +G + EVD+K + YGF++FE+ + A ++
Sbjct: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK-------NGYGFVEFEDSRDADDAVYELN 56
Query: 436 GKIIIRNPIKIGYGKATPTTRLWV-----GGLGPWVPLAALAREFDRFGTIRTIDYRKGD 490
GK + + + + + R G G + R D++G +YR
Sbjct: 57 GKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGR--DKYGPPVRTEYR--- 111
Query: 491 SWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVT 550
+ E+L ++ +W ++ F + V +AD H E
Sbjct: 112 ----LIVENL-SSRCSWQDLKDFMRQAGE----VTYAD---------------AHKERTN 147
Query: 551 D-AFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYE 609
+ R+ ++ A D+ R+ L D P R + + + S
Sbjct: 148 EGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK------PRTSHRRSYSGSRS----- 196
Query: 610 PLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAP 669
S RRR R R S+ + R R S GR RS K P
Sbjct: 197 --RSRSRRRSRSRSRRSSRSRSRSISKSRSRSR---SRSKGRSRSRSKGRKSRSKSKSKP 251
Query: 670 SPDR---SPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLE-KSQGDKRDRKNSASA 725
DR S S S+D Y RS SP + +G ++ KS+ + R NS
Sbjct: 252 KSDRGSHSHSRSRSKDEYEKSRSRS-----RSRSPKENGKGDIKSKSRSRSQSRSNSPLP 306
Query: 726 ERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSK 762
K R+ +P ++ + RS + S S +SS+
Sbjct: 307 VPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 50.8 bits (120), Expect = 6e-06
Identities = 71/333 (21%), Positives = 121/333 (36%), Gaps = 53/333 (15%)
Query: 456 RLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPL 515
R+++G L V + R F +G + +D + G + ++++E A A + G L
Sbjct: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNG--YGFVEFEDSRDADDAVYELNGKEL 60
Query: 516 GGPDRRLRVDFADTEHRYQQQYLQ---------------------PLPLTHYELVTDAFG 554
G R+ V+ A R + Y P T Y L+ +
Sbjct: 61 CG--ERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLS 118
Query: 555 HRAP-DPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDS 613
R L+ + + Y D ++ T +Y +
Sbjct: 119 SRCSWQDLKDFMRQAGEVTYADAHKE-----------------RTNEGVIEFRSYSDMKR 161
Query: 614 LDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDR 673
+ DG ++ R++ D+PR SG R RS R R R + S R
Sbjct: 162 ALDKLDGTEIN----GRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRS--R 215
Query: 674 SPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRT 733
S +S SR R S + SR R + R S K + D+ +S S +D ++
Sbjct: 216 SRSISKSRSRSRSRSKGRSR---SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKS 272
Query: 734 TAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSP 766
+ + +SP K+ + D + S S + S+ SP
Sbjct: 273 RSRSRSRSP-KENGKGDIKSKSRSRSQSRSNSP 304
Score = 36.6 bits (83), Expect = 0.12
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 15/136 (11%)
Query: 32 TQLRGDDLR----RPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGK 87
T++ G ++R +P T + S ++ RSR S SR RS + S S +
Sbjct: 169 TEINGRNIRLIEDKPRTSHRRSYSGSRS-RSRSRRRSRSRSRRSSRSRSRSISKSRSRSR 227
Query: 88 TDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSR-- 145
+ S G SR KS S+ S+ G HS+S +K+ SRS SR
Sbjct: 228 SRSKGRSRSRSKGRKSRSKSKSKPKSDRGS------HSHSRSRSKDEYEKSRSRSRSRSP 281
Query: 146 --GGGGESRSSGAASS 159
G G+ +S + S
Sbjct: 282 KENGKGDIKSKSRSRS 297
Score = 32.0 bits (71), Expect = 2.9
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 688 NDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKED 747
N R+ RL+ ++P R S S+ R R+ S S R R R+ + + KS +
Sbjct: 172 NGRNIRLIEDKPR--TSHRRSYSGSRSRSRSRRRSRSRSR-RSSRSRSRSISKSRSRSRS 228
Query: 748 RSDGSAPSTSTA-SSKLKSPSQ-KQDGGT 774
RS G + S S S+ KS S+ K D G+
Sbjct: 229 RSKGRSRSRSKGRKSRSKSKSKPKSDRGS 257
Score = 31.6 bits (70), Expect = 3.8
Identities = 47/158 (29%), Positives = 64/158 (40%), Gaps = 22/158 (13%)
Query: 12 RSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRG----------G 61
RS RR+ S+ R + R + KG+ RS K ++SR G
Sbjct: 197 RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRG 256
Query: 62 EDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSS 121
S SR RSK S S ++G G +S KS SR SR ++ S
Sbjct: 257 SHSHSR-SRSKDEYEKSRSRSRSRSPKENGKGDIKS----KSRSRSQSRS-NSPLPVPPS 310
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASS 159
+ S S P + +S SRS SR +SRS +SS
Sbjct: 311 KARSVSPPPKRATS---RSRSRSR---SKSRSRSRSSS 342
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 52.0 bits (123), Expect = 3e-06
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 2/100 (2%)
Query: 64 STSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSS--SRGGSREYDTGGGSSSS 121
ST G GG GGS+G+ G GGGS + +L +S S GG GGG +SS
Sbjct: 72 STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAP 161
+ S+ S+ +SS S SSS S S G P
Sbjct: 132 TPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Score = 31.6 bits (70), Expect = 3.8
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 23/130 (17%)
Query: 42 PATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSG--GSNGSSSGKTDSGGGSRRSLH 99
P T + P+ S G +++ S G S+G + + + + +
Sbjct: 9 PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAA 68
Query: 100 LDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS---GA 156
S+ GG GGG SS N GGG GGGG S + A
Sbjct: 69 TVTSTGGGGGGGGSGGGGGSSG-----------NGGGGG-------GGGGGSNCNPNLAA 110
Query: 157 ASSAPGGGDG 166
AS+ GGG G
Sbjct: 111 ASNGSGGGGG 120
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 52.0 bits (123), Expect = 3e-06
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 2/100 (2%)
Query: 64 STSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSS--SRGGSREYDTGGGSSSS 121
ST G GG GGS+G+ G GGGS + +L +S S GG GGG +SS
Sbjct: 72 STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAP 161
+ S+ S+ +SS S SSS S S G P
Sbjct: 132 TPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Score = 31.6 bits (70), Expect = 3.8
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 23/130 (17%)
Query: 42 PATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSG--GSNGSSSGKTDSGGGSRRSLH 99
P T + P+ S G +++ S G S+G + + + + +
Sbjct: 9 PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAA 68
Query: 100 LDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS---GA 156
S+ GG GGG SS N GGG GGGG S + A
Sbjct: 69 TVTSTGGGGGGGGSGGGGGSSG-----------NGGGGG-------GGGGGSNCNPNLAA 110
Query: 157 ASSAPGGGDG 166
AS+ GGG G
Sbjct: 111 ASNGSGGGGG 120
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 52.0 bits (123), Expect = 3e-06
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 2/100 (2%)
Query: 64 STSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSS--SRGGSREYDTGGGSSSS 121
ST G GG GGS+G+ G GGGS + +L +S S GG GGG +SS
Sbjct: 72 STGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAP 161
+ S+ S+ +SS S SSS S S G P
Sbjct: 132 TPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Score = 31.6 bits (70), Expect = 3.8
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 23/130 (17%)
Query: 42 PATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSG--GSNGSSSGKTDSGGGSRRSLH 99
P T + P+ S G +++ S G S+G + + + + +
Sbjct: 9 PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAA 68
Query: 100 LDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSS---GA 156
S+ GG GGG SS N GGG GGGG S + A
Sbjct: 69 TVTSTGGGGGGGGSGGGGGSSG-----------NGGGGG-------GGGGGSNCNPNLAA 110
Query: 157 ASSAPGGGDG 166
AS+ GGG G
Sbjct: 111 ASNGSGGGGG 120
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 52.0 bits (123), Expect = 3e-06
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 6/141 (4%)
Query: 350 GAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIK-RP 408
G G + E +I ++ +F+G L T+ DL+ F +FG + + +K P
Sbjct: 54 GGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDP 113
Query: 409 SRGQTSTYGFLKF---ENLD-MSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGP 464
G++ +GF+ F E++D + + + ++GK+I K K P +++VGGL P
Sbjct: 114 ITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK-EPVKKIFVGGLSP 172
Query: 465 WVPLAALAREFDRFGTIRTID 485
P + F FG + +I+
Sbjct: 173 DTPEEKIREYFGGFGEVESIE 193
>gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d
[Homo sapiens]
Length = 287
Score = 52.0 bits (123), Expect = 3e-06
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 6/141 (4%)
Query: 350 GAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIK-RP 408
G G + E +I ++ +F+G L T+ DL+ F +FG + + +K P
Sbjct: 54 GGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDP 113
Query: 409 SRGQTSTYGFLKF---ENLD-MSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGP 464
G++ +GF+ F E++D + + + ++GK+I K K P +++VGGL P
Sbjct: 114 ITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK-EPVKKIFVGGLSP 172
Query: 465 WVPLAALAREFDRFGTIRTID 485
P + F FG + +I+
Sbjct: 173 DTPEEKIREYFGGFGEVESIE 193
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 52.0 bits (123), Expect = 3e-06
Identities = 44/131 (33%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 60 GGEDSTSRGERSKKLGGSGG------SNGSSSGKTDSG---GGSRRSLHLDKSSSRGGSR 110
GG S S G + G SG +NGSSSG + SG GGS S + GGSR
Sbjct: 238 GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
Query: 111 EYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYK 170
D+G SS SS + S GG + G E+R SG + G G
Sbjct: 298 G-DSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSN 356
Query: 171 TLKISELGSQL 181
+IS+ G++L
Sbjct: 357 MREISKEGNRL 367
Score = 48.9 bits (115), Expect = 2e-05
Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 81 NGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGES 140
+GS G ++SGGGS S S G + + GGSSS S S S+ SSGG
Sbjct: 235 SGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG---SSSGGSSGGSSGGSSG 291
Query: 141 RS-SSRGGGGESRSSGAASSAPGGGDG 166
S SRG G S G+++ + G G
Sbjct: 292 NSGGSRGDSGSESSWGSSTGSSSGNHG 318
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 14/105 (13%)
Query: 76 GSGGSNGSSSGKTDSGG-------GSRRSLHLDK-------SSSRGGSREYDTGGGSSSS 121
G GG+ G + T++ G GS R+ + ++ S S GGS G GS S
Sbjct: 194 GQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
Query: 122 RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDG 166
S S+ N S G S S S GG SSG +S GG G
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Score = 31.2 bits (69), Expect = 5.0
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 5/89 (5%)
Query: 75 GGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNS 134
G S GS G + G G ++++G + G +S++ ++P S
Sbjct: 178 GNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGS 237
Query: 135 SGGGESRSSSRGGGGESRSSGAASSAPGG 163
GG SS GGG SG++ S G
Sbjct: 238 GGG-----SSNSGGGSGSQSGSSGSGSNG 261
Score = 31.2 bits (69), Expect = 5.0
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 7/99 (7%)
Query: 58 SRGGEDSTSRGERSKKLGGS--GGSNGSSSGK-TDSGGGSRRSLHLDK--SSSRGGSREY 112
S GG S G R S G S GSSSG SGGG+ +K + +RG
Sbjct: 285 SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
Query: 113 DTG--GGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGG 149
G G SS + S + G G++ +S G
Sbjct: 345 IQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,380,446
Number of Sequences: 37866
Number of extensions: 2585174
Number of successful extensions: 27322
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 761
Number of HSP's that attempted gapping in prelim test: 16818
Number of HSP's gapped (non-prelim): 6756
length of query: 977
length of database: 18,247,518
effective HSP length: 112
effective length of query: 865
effective length of database: 14,006,526
effective search space: 12115644990
effective search space used: 12115644990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.