Guide to the Human Genome
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Search of human proteins with 4759166

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759166 secreted phosphoprotein 1 isoform b [Homo sapiens]
         (300 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759166 secreted phosphoprotein 1 isoform b [Homo sapiens]         616   e-177
gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens]        606   e-174
gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens]        553   e-158
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    64   1e-10
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   49   5e-06
gi|115529449 upstream binding transcription factor, RNA polymera...    48   1e-05
gi|115529451 upstream binding transcription factor, RNA polymera...    48   1e-05
gi|7657671 upstream binding transcription factor, RNA polymerase...    48   1e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    46   5e-05
gi|55956788 nucleolin [Homo sapiens]                                   45   6e-05
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    45   8e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      45   8e-05
gi|217330641 IWS1 homolog [Homo sapiens]                               45   8e-05
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       45   1e-04
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    45   1e-04
gi|16445033 ACRC protein [Homo sapiens]                                44   2e-04
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    44   2e-04
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     41   0.001
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    40   0.002
gi|7661622 hypothetical protein LOC25906 [Homo sapiens]                40   0.002
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    40   0.002
gi|4504487 histidine rich calcium binding protein precursor [Hom...    40   0.003
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          40   0.003
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]    39   0.004
gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]    39   0.004
gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]    39   0.004
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]     39   0.004
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]     39   0.004
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       39   0.006
gi|31543091 MAK16 homolog [Homo sapiens]                               39   0.007

>gi|4759166 secreted phosphoprotein 1 isoform b [Homo sapiens]
          Length = 300

 Score =  616 bits (1588), Expect = e-177
 Identities = 300/300 (100%), Positives = 300/300 (100%)

Query: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL 60
           MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL
Sbjct: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL 60

Query: 61  PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT 120
           PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
Sbjct: 61  PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT 120

Query: 121 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME 180
           DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
Sbjct: 121 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME 180

Query: 181 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES 240
           SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
Sbjct: 181 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES 240

Query: 241 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN 300
           NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
Sbjct: 241 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN 300


>gi|91206462 secreted phosphoprotein 1 isoform a [Homo sapiens]
          Length = 314

 Score =  606 bits (1563), Expect = e-174
 Identities = 300/314 (95%), Positives = 300/314 (95%), Gaps = 14/314 (4%)

Query: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQ-- 58
           MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQ  
Sbjct: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA 60

Query: 59  ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS 106
                       TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
Sbjct: 61  VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS 120

Query: 107 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ 166
           DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
Sbjct: 121 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ 180

Query: 167 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH 226
           YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
Sbjct: 181 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH 240

Query: 227 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF 286
           KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
Sbjct: 241 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF 300

Query: 287 RISHELDSASSEVN 300
           RISHELDSASSEVN
Sbjct: 301 RISHELDSASSEVN 314


>gi|91598939 secreted phosphoprotein 1 isoform c [Homo sapiens]
          Length = 287

 Score =  553 bits (1424), Expect = e-158
 Identities = 276/300 (92%), Positives = 279/300 (93%), Gaps = 13/300 (4%)

Query: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL 60
           MRIAVICFCLLGITCAIPVKQADSGSSEEKQ             N   S++ N    +TL
Sbjct: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQ-------------NAVSSEETNDFKQETL 47

Query: 61  PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT 120
           PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT
Sbjct: 48  PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVT 107

Query: 121 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME 180
           DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME
Sbjct: 108 DFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHME 167

Query: 181 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES 240
           SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES
Sbjct: 168 SEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDES 227

Query: 241 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN 300
           NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
Sbjct: 228 NEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN 287


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 54/210 (25%), Positives = 92/210 (43%), Gaps = 24/210 (11%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTD 121
           S S++S+D  +  D  D  +  DS +S DS+DS D  D+D S+ SD S+ SD SD   + 
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839

Query: 122 FPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPD-IQYPDATD-EDITSHM 179
             +D            + D+ DG          S S    R D     D++D  D ++  
Sbjct: 840 DSSD------------SSDSSDG----------SDSDSSNRSDSSNSSDSSDSSDSSNSS 877

Query: 180 ESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDE 239
           +S + + + ++   +   ++ +  DS   DS  +S   D S  + S + S       + +
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937

Query: 240 SNEHSDVIDSQELSKVSREFHSHEFHSHED 269
           S+  SD  DS + S  S   +S +  +  D
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 58/236 (24%), Positives = 88/236 (37%), Gaps = 15/236 (6%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTD 121
            S S++S D  D  +  D  +  DS +S DS+DS+  D +D S+ SD S  SD SD     
Sbjct: 939  SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS---- 994

Query: 122  FPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMES 181
              +D   +   +    + D+ D    S        S      D      + +   S   S
Sbjct: 995  --SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 182  EELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESN 241
            +  N        + D +  SD  S   DS ++S   D S  + S   S       + +S+
Sbjct: 1053 DSSN--------SSDSSDSSD-SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103

Query: 242  EHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASS 297
            + SD  DS + S  S   +S +     D       S   D       S   DS+ S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 65/278 (23%), Positives = 107/278 (38%), Gaps = 16/278 (5%)

Query: 22  ADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDD 81
           +DS SS+     N       +  + D S   N  +  +  S S+ S D  D  D  +  D
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSDSSNSSD 766

Query: 82  HVDSQDSIDSNDSDDVDDTDD-SHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVD 140
             DS DS DS+DS +  D++D S+ SD S  S+ SD   +   +D            + D
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD------------SSD 814

Query: 141 TYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAP 200
           + D    +      S             D++D    S  +S   + +  +   +   ++ 
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874

Query: 201 SDWDSR-GKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREF 259
           +  DS    DS E+S   D S  ++S          ++D S++ S+  DS E S  S   
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD-SSDSSNSSDSSESSNSSDNS 933

Query: 260 HSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASS 297
           +S +  +  D       S   D       S+  DS+ S
Sbjct: 934 NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 63/278 (22%), Positives = 101/278 (36%), Gaps = 4/278 (1%)

Query: 23  DSGS-SEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDD 81
           D+G+ S+ K   +   D+ +   N D +   N        S S +      D D  D  +
Sbjct: 500 DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559

Query: 82  HVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDT 141
             DS DS DS+ SD    +D      +S  S +SD   +   +D   +   +    + D+
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619

Query: 142 YDGRGDSVVYGLRS--KSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNA 199
            D + DS      S     K    D    D++D   +S   +   +        + D ++
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 200 PSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREF 259
            SD  S   DS ++S   + S  + S   S      ++D SN +S   DS   S  S   
Sbjct: 680 SSD-SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738

Query: 260 HSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASS 297
           +S +     D       S   D       S   DS+ S
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 62/277 (22%), Positives = 107/277 (38%), Gaps = 15/277 (5%)

Query: 21  QADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDD 80
           ++DSG  +     +   D+  +  + D S   +  +     S S+ S     D  D D  
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS--SDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 81  DHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVD 140
           D  +S DS DS+DS D  D+ DS  S       ESD   +D  +D   +        + D
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN-------SSD 649

Query: 141 TYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAP 200
           + D    S      + S      D     ++ +   S   S+  + +  +   + D +  
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS--ESSDSSDS 707

Query: 201 SDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFH 260
           SD DS   DS ++S  +  S+++ S   S       + +S++ SD  +S + S  S   +
Sbjct: 708 SDSDS--SDSSDSS--NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 261 SHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASS 297
           S +     D       S   D +     S   DS++S
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQ-SDESHHSDESD 116
            S S++S D  D  D  D  D  DS DS DS+DS D  D+ DS++ SD S  SD SD
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 26/56 (46%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD-VDDTDDSHQSDESHHSDESD 116
            S S++S D  D  D  D  D  DS DS DS+DS++  D +D S  SD S+ SD SD
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 53/289 (18%), Positives = 103/289 (35%), Gaps = 30/289 (10%)

Query: 19  VKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDM---- 74
           V  +++GS      Y+ Y     +    DP+            S+S+ +     D     
Sbjct: 436 VGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNS 495

Query: 75  DDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTP 134
           D+  D+ +       + +DSD   DT++S  +   ++ ++ ++                 
Sbjct: 496 DESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND----------------- 538

Query: 135 VVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVA 194
                D+  G+ DS        S      D    D++D + +S  +S + + +  +   +
Sbjct: 539 ---KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595

Query: 195 QDLNAPSDW-----DSRGKDSYETSQLDDQSAETHSHKQSRLYKRKAND-ESNEHSDVID 248
            D +  SD       S   DS ++S     S+++ S       K  ++D  S++ SD  D
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655

Query: 249 SQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASS 297
           S + S  S    S +     D       S   D       S+  +S+ S
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 52/251 (20%), Positives = 89/251 (35%), Gaps = 8/251 (3%)

Query: 49  SQKQNLLAPQTLPSKSNESHDHMDDMDDED--DDDHVDSQDSIDSNDSDDVDDTDDSHQS 106
           S+  N +      S SN       D DD+    DD   S +S  ++D++   D + S + 
Sbjct: 430 SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRG 489

Query: 107 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ 166
           D S++SDES +      +   A +  +      +  D  G+       + +    + D  
Sbjct: 490 DASYNSDESKDNGNGSDSK-GAEDDDSDSTSDTNNSDSNGNG-----NNGNDDNDKSDSG 543

Query: 167 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH 226
              +   D  S   S   + +  +   + D N+ SD DS   DS ++S  D   +   S 
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603

Query: 227 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF 286
                    ++D S+      DS +    S +  S    S  +       S   D     
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663

Query: 287 RISHELDSASS 297
             S   DS+ S
Sbjct: 664 NSSDSSDSSDS 674



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 23/56 (41%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDS-DDVDDTDDSHQSDESHHSDESD 116
            S SNES D  D  D  D  +  DS DS DS+DS  D +D  DS     + +++ SD
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSD 1284



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDD-TDDSH-QSDESHHSDESDELV 119
            S S++S D  +  D  D  D  DS +S DS+DS D  D T DS+ +SD    S   +   
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNG 1282

Query: 120  TDFPTD 125
            +D  +D
Sbjct: 1283 SDSDSD 1288



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 15/55 (27%), Positives = 25/55 (45%)

Query: 62   SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
            S S++S D  D  D   D +      S   N +++  D+D   +  +S+HS   D
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTD 121
           SK  E  DH      EDD D    Q+S DS +  D +  +D H   +   + +S+E    
Sbjct: 277 SKGQEGQDH----GKEDDHDSSIGQNS-DSKEYYDPEGKEDPHNEVDGDKTSKSEENSAG 331

Query: 122 FPTD 125
            P D
Sbjct: 332 IPED 335


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 21/65 (32%), Positives = 38/65 (58%)

Query: 52  QNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHH 111
           + LLA +   S+S+ S D    +D+++DDD  +  D  D+++ DD +D D++  +DE   
Sbjct: 317 KKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDED 376

Query: 112 SDESD 116
            DE +
Sbjct: 377 DDEEE 381


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 19/106 (17%)

Query: 26  SSEEKQLYNKYPD----AVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDD 81
           S +++  Y +Y      ++     P+P   +      TL SKS    D  +D DDED+D+
Sbjct: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRT-----TLQSKSESEEDDEEDEDDEDEDE 655

Query: 82  HV----------DSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
                       D  DS +S+  D+ +D D++ + DE    DE D+
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 701



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           S  + S D  +D D+ ++DD  D  D  D +D +D D+  +   S  S   D SD
Sbjct: 672 SSESSSEDESEDGDENEEDDE-DEDD--DEDDDEDEDNESEGSSSSSSSSGDSSD 723


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 19/106 (17%)

Query: 26  SSEEKQLYNKYPD----AVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDD 81
           S +++  Y +Y      ++     P+P   +      TL SKS    D  +D DDED+D+
Sbjct: 601 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRT-----TLQSKSESEEDDEEDEDDEDEDE 655

Query: 82  HV----------DSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
                       D  DS +S+  D+ +D D++ + DE    DE D+
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 701



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           S  + S D  +D D+ ++DD  D  D  D +D +D D+  +   S  S   D SD
Sbjct: 672 SSESSSEDESEDGDENEEDDE-DEDD--DEDDDEDEDNESEGSSSSSSSSGDSSD 723


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 29/106 (27%), Positives = 48/106 (45%), Gaps = 19/106 (17%)

Query: 26  SSEEKQLYNKYPD----AVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDD 81
           S +++  Y +Y      ++     P+P   +      TL SKS    D  +D DDED+D+
Sbjct: 638 SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRT-----TLQSKSESEEDDEEDEDDEDEDE 692

Query: 82  HV----------DSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
                       D  DS +S+  D+ +D D++ + DE    DE D+
Sbjct: 693 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDD 738



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           S  + S D  +D D+ ++DD  D  D  D +D +D D+  +   S  S   D SD
Sbjct: 709 SSESSSEDESEDGDENEEDDE-DEDD--DEDDDEDEDNESEGSSSSSSSSGDSSD 760


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 73/324 (22%), Positives = 121/324 (37%), Gaps = 58/324 (17%)

Query: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVAT--WLNPDPSQKQNLLAPQ 58
           M+I+++   L G++CA+PV +  +  SE+ + +  +     T    N DPS      + Q
Sbjct: 1   MKISILLMFLWGLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPLANEDPSD-----STQ 55

Query: 59  TLPSKSNESHDHM---------------DDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDS 103
           +     ++ H ++               DD DD++DD              DD    DDS
Sbjct: 56  SEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDD------------SGDDTFGDDDS 103

Query: 104 HQSDESHHSDESDELVTDFPTD--LPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFR 161
               +      +  L +D  +D  + A+E   P          +G        S+S++  
Sbjct: 104 GPGPKDRQEGGNSRLGSDEDSDDTIQASEESAP----------QGQDSAQDTTSESRELD 153

Query: 162 RPDIQYPDATDEDITSHMESEE--LNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQ 219
             D         D T   ESEE  + G         D    S+ D  G  S +   +  +
Sbjct: 154 NEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD---GSELDDEGMQSDDPESI--R 208

Query: 220 SAETHSHKQSRLYKRKANDESNEHSDVID---SQELSKVSREFHSHEFHSHED--MLVVD 274
           S   +S   S   K K + E++E ++  D   SQ L   SR+       S ED    + D
Sbjct: 209 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD 268

Query: 275 PKSKEEDKHLKFRISHELDSASSE 298
             + EE K      S+  D+  S+
Sbjct: 269 NNTMEEVKSDSTENSNSRDTGLSQ 292



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 49/215 (22%)

Query: 76  DEDDDDHVDSQDSIDSNDSDDVD-----DTDDSHQSDESHHSDESDELVTDFPTDLPATE 130
           D   D   DS++++   +S +VD      + +++ S + + S+  +E+V++   D P  +
Sbjct: 296 DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNP--D 353

Query: 131 VFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKA 190
             T  V   +  D   +   + L S SK   R + Q    + E +    ES E       
Sbjct: 354 PTTSYVEDQEDSDSSEEDSSHTL-SHSKSESREE-QADSESSESLNFSEESPE------- 404

Query: 191 IPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQ 250
                   +P D +S    S E  Q    SAE+ S            +ES+   D  DSQ
Sbjct: 405 --------SPEDENS---SSQEGLQSHSSSAESQS------------EESHSEEDDSDSQ 441

Query: 251 ELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLK 285
           + S+   + +S E  S          S EED  LK
Sbjct: 442 DSSRSKEDSNSTESKS----------SSEEDGQLK 466



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 62/287 (21%), Positives = 109/287 (37%), Gaps = 53/287 (18%)

Query: 19  VKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESH-DHMDDMDDE 77
           +K  +SG + E+       D+  + L   PS+K        +  KS  S  D   ++DD 
Sbjct: 221 MKSKESGENSEQA---NTQDSGGSQLLEHPSRK--------IFRKSRISEEDDRSELDDN 269

Query: 78  DDDDHVDSQDSIDSNDSDDV------DDTDDSHQSDESHHSDESDELVTDFPTDLPATEV 131
           +  + V S  + +SN  D        D   DS +  + + S E  + V     D P++E 
Sbjct: 270 NTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNV-----DGPSSE- 323

Query: 132 FTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAI 191
                    + +    S      S+ +         PD T    TS++E +E + +    
Sbjct: 324 --------SSQEANLSSQENSSESQEEVVSESRGDNPDPT----TSYVEDQEDSDS---- 367

Query: 192 PVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQE 251
                    S+ DS    S+  S+  ++ A++ S +     +       +E+S   +  +
Sbjct: 368 ---------SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQ 418

Query: 252 LSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSE 298
               S E  S E HS ED    D  S++  +  +   S E  S+S E
Sbjct: 419 SHSSSAESQSEESHSEED----DSDSQDSSRSKEDSNSTESKSSSEE 461



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 20  KQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLA-PQTLPSKSNESHDHMDDMDDED 78
           +QADS SSE      + P++     + + S ++ L +   +  S+S ESH   DD D +D
Sbjct: 386 EQADSESSESLNFSEESPESPE---DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 442

Query: 79  DDDHVDSQDSIDSNDSDDVD 98
                +  +S +S  S + D
Sbjct: 443 SSRSKEDSNSTESKSSSEED 462


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 36/150 (24%), Positives = 59/150 (39%), Gaps = 42/150 (28%)

Query: 16  AIPVKQADSGSSEEKQLYNKYPDAVATWL---NPDPSQKQNLLAPQTLPSKS----NESH 68
           AIP K A +G + +K+  ++  D  +      + D  + ++ + P  + + +    +E  
Sbjct: 128 AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDE 187

Query: 69  DHMDDMDDEDDDDHVDS-----------------------------------QDSIDSND 93
           D  DD DDEDDDD  +                                    +D  D +D
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDD 247

Query: 94  SDDVDDTDDSHQSDESHHSDESDELVTDFP 123
            DD DD DD  + DE    +E +E V + P
Sbjct: 248 DDDEDDEDDDDEDDEEEEEEEEEEPVKEAP 277



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 38/188 (20%), Positives = 68/188 (36%), Gaps = 46/188 (24%)

Query: 64  SNESHDHMDDMDDEDDDDHVDSQDSID---------SNDSDDVDDTDDSHQSDESHHSDE 114
           S+E  D   + D+EDD+D  + +D I+         +  S+D DD DD  + DE    DE
Sbjct: 145 SDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD--EDDEDDDDDE 202

Query: 115 SDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDED 174
            D+   +                 ++T   +G      +  K+K     + +  D  DED
Sbjct: 203 EDDSEEE----------------AMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED 246

Query: 175 ITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKR 234
                + E                   D D    +  E  + ++   E    ++  + K+
Sbjct: 247 DDDDEDDE-------------------DDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287

Query: 235 KANDESNE 242
           KA  E+ +
Sbjct: 288 KAAPEAKK 295


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 71/327 (21%), Positives = 119/327 (36%), Gaps = 48/327 (14%)

Query: 1   MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTL 60
           M+I+++   L G++CA+PV +  +  SE+ + +  +     T     P +         +
Sbjct: 1   MKISILLMFLWGLSCALPVTRYQNNESEDSEEWKGHLAQAPT----PPLESSESSEGSKV 56

Query: 61  PSKSNESHDHMDDMDDED---DDDHV-----------------DSQDSIDSNDSDDVDDT 100
            S+   + D  D    E+    DDH                  D +D  + +  DD    
Sbjct: 57  SSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGD 116

Query: 101 DDSHQSDESHHSDESDELVTDFPTD--LPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSK 158
           DDS    +      +  L +D  +D  + A+E   P          +G        S+S+
Sbjct: 117 DDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAP----------QGQDSAQDTTSESR 166

Query: 159 KFRRPDIQYPDATDEDITSHMESEE--LNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL 216
           +    D         D T   ESEE  + G         D    S+ D  G  S +   +
Sbjct: 167 ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD---GSELDDEGMQSDDPESI 223

Query: 217 DDQSAETHSHKQSRLYKRKANDESNEHSDVID---SQELSKVSREFHSHEFHSHED--ML 271
             +S   +S   S   K K + E++E ++  D   SQ L   SR+       S ED    
Sbjct: 224 --RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSE 281

Query: 272 VVDPKSKEEDKHLKFRISHELDSASSE 298
           + D  + EE K      S+  D+  S+
Sbjct: 282 LDDNNTMEEVKSDSTENSNSRDTGLSQ 308



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 49/215 (22%)

Query: 76  DEDDDDHVDSQDSIDSNDSDDVD-----DTDDSHQSDESHHSDESDELVTDFPTDLPATE 130
           D   D   DS++++   +S +VD      + +++ S + + S+  +E+V++   D P  +
Sbjct: 312 DSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNP--D 369

Query: 131 VFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKA 190
             T  V   +  D   +   + L S SK   R + Q    + E +    ES E       
Sbjct: 370 PTTSYVEDQEDSDSSEEDSSHTL-SHSKSESREE-QADSESSESLNFSEESPE------- 420

Query: 191 IPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQ 250
                   +P D +S    S E  Q    SAE+ S            +ES+   D  DSQ
Sbjct: 421 --------SPEDENS---SSQEGLQSHSSSAESQS------------EESHSEEDDSDSQ 457

Query: 251 ELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLK 285
           + S+   + +S E  S          S EED  LK
Sbjct: 458 DSSRSKEDSNSTESKS----------SSEEDGQLK 482



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 62/287 (21%), Positives = 109/287 (37%), Gaps = 53/287 (18%)

Query: 19  VKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESH-DHMDDMDDE 77
           +K  +SG + E+       D+  + L   PS+K        +  KS  S  D   ++DD 
Sbjct: 237 MKSKESGENSEQA---NTQDSGGSQLLEHPSRK--------IFRKSRISEEDDRSELDDN 285

Query: 78  DDDDHVDSQDSIDSNDSDDV------DDTDDSHQSDESHHSDESDELVTDFPTDLPATEV 131
           +  + V S  + +SN  D        D   DS +  + + S E  + V     D P++E 
Sbjct: 286 NTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNV-----DGPSSE- 339

Query: 132 FTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAI 191
                    + +    S      S+ +         PD T    TS++E +E + +    
Sbjct: 340 --------SSQEANLSSQENSSESQEEVVSESRGDNPDPT----TSYVEDQEDSDS---- 383

Query: 192 PVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQE 251
                    S+ DS    S+  S+  ++ A++ S +     +       +E+S   +  +
Sbjct: 384 ---------SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQ 434

Query: 252 LSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSE 298
               S E  S E HS ED    D  S++  +  +   S E  S+S E
Sbjct: 435 SHSSSAESQSEESHSEED----DSDSQDSSRSKEDSNSTESKSSSEE 477



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 20  KQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLA-PQTLPSKSNESHDHMDDMDDED 78
           +QADS SSE      + P++     + + S ++ L +   +  S+S ESH   DD D +D
Sbjct: 402 EQADSESSESLNFSEESPESPE---DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 458

Query: 79  DDDHVDSQDSIDSNDSDDVD 98
                +  +S +S  S + D
Sbjct: 459 SSRSKEDSNSTESKSSSEED 478


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 17/50 (34%), Positives = 29/50 (58%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHH 111
           S+  E  +H DD +DEDD+D  D  D  D +D +D +D +D  + ++  +
Sbjct: 245 SEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRY 294



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 16/51 (31%), Positives = 27/51 (52%)

Query: 64  SNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDE 114
           S ES +  +D + EDD +  D +D  D +D DD DD +D    ++    ++
Sbjct: 241 SVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQ 291



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 15/47 (31%), Positives = 23/47 (48%), Gaps = 5/47 (10%)

Query: 71  MDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           ++  ++ +D +H D     D  D DD DD DD    D+    D+ DE
Sbjct: 242 VESSEEGEDQEHED-----DGEDEDDEDDDDDDDDDDDDDDEDDEDE 283



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 11/46 (23%), Positives = 20/46 (43%)

Query: 72  DDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           ++  D  +     S++  D    DD +D DD    D+    D+ D+
Sbjct: 232 EETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDD 277


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 61/308 (19%), Positives = 120/308 (38%), Gaps = 40/308 (12%)

Query: 20  KQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHD----HMDDMD 75
           +Q DS S  E++      D+    +N   S  ++    + LP   +E+ +    H  D +
Sbjct: 89  RQKDSDSESEERAEPPASDSENEDVNQHGSDSESE-ETRKLPGSDSENEELLNGHASDSE 147

Query: 76  DEDDDDH-----------------VDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDEL 118
           +ED   H                  +++D++    SD   +    HQ+ +S + +     
Sbjct: 148 NEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPR 207

Query: 119 VTDFPT-DLPATEVF---TPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDED 174
           ++D  + +LP  +V    +   P     D   + +     S S+    P  Q  D+ +E+
Sbjct: 208 MSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEE 267

Query: 175 I----TSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSR 230
           +     S  ESE+      +    ++L  P   DS  +   +    D ++ +   HKQ  
Sbjct: 268 LPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQ-- 325

Query: 231 LYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISH 290
             K +++D+S+  +     ++    +  FHS    SH D         EE++H K ++  
Sbjct: 326 --KPESDDDSDREN---KGEDTEMQNDSFHS---DSHMDRKKFHSSDSEEEEHKKQKMDS 377

Query: 291 ELDSASSE 298
           + D    E
Sbjct: 378 DEDEKEGE 385



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 58/292 (19%), Positives = 116/292 (39%), Gaps = 31/292 (10%)

Query: 26  SSEEKQLYNKYP--DAVATWLNPDP---SQKQNLLAPQTLPSKSNESHDHMDDMDDEDDD 80
           S  E +   K+P  D+    L   P   S+ ++ L PQ   S+S E   H    D E+++
Sbjct: 144 SDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQAS-DSENEE 202

Query: 81  DHVDSQDSIDSND------SDDVDDTDDSHQSDESHHSDESDELVTDFPTDLP----ATE 130
                    +S +      SD   +    HQ+ +S + +     ++D  ++ P    A++
Sbjct: 203 PPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASD 262

Query: 131 VFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDI----TSHMESEELNG 186
                +P     D   +       S S+    P  +  D+  E       S  E+E+ + 
Sbjct: 263 SENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDAS- 321

Query: 187 AYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDV 246
            +K  P + D    SD +++G+D+    ++ + S  + SH   + +    ++E       
Sbjct: 322 RHKQKPESDD---DSDRENKGEDT----EMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQK 374

Query: 247 IDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSE 298
           +DS E  K   E    +    +  ++ D + +E+    K R+  + D + S+
Sbjct: 375 MDSDEDEKEGEE---EKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSD 423



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 50/229 (21%), Positives = 85/229 (37%), Gaps = 25/229 (10%)

Query: 75  DDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQ-----SDESHHSDESDELVTDFPTDLPAT 129
           D  DD      QD  DS  SD  DD ++ H      S E H  +E+ +     P     T
Sbjct: 9   DQSDDGGATPVQDERDSG-SDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVT 67

Query: 130 EVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSH---MESEELNG 186
           +        ++  D   + +     S S+   R +    D+ +ED+  H    ESEE   
Sbjct: 68  DSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEET-- 125

Query: 187 AYKAIPVAQDLN--------APSDWDSRGKDSYETSQLDD--QSAETHSHKQSRLYKRKA 236
             + +P +   N        + S+ +  GK     S++++  +S  + S  +  L  + +
Sbjct: 126 --RKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQIS 183

Query: 237 NDESNE--HSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKH 283
           + ES E       DS+            E        V D +S+E  +H
Sbjct: 184 DSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRH 232



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 41/218 (18%), Positives = 72/218 (33%), Gaps = 49/218 (22%)

Query: 57  PQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           PQ  P+  +E+ D        + DD  D ++  +  +  +     DSH   +  HS +S+
Sbjct: 307 PQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSE 366

Query: 117 ELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDIT 176
           E                                      +  K ++ D      +DED  
Sbjct: 367 E--------------------------------------EEHKKQKMD------SDED-- 380

Query: 177 SHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKA 236
              E EE   A +   V  D  +  +  +  K S   S  DD  ++  S K  +  K  A
Sbjct: 381 -EKEGEEEKVAKRKAAVLSD--SEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIA 437

Query: 237 NDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVD 274
           +D   E    +  ++  +        E  + E+ L+ D
Sbjct: 438 SDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIAD 475


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 22/113 (19%)

Query: 26   SSEEKQLYNKYPDAVATWLN----------------PDPSQKQNLL--APQTLPSKSN-- 65
            SS+E Q+ N+  D +   L                  D SQ+  L+  AP  L   S   
Sbjct: 2338 SSQEMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQ 2397

Query: 66   -ESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
                D M+ +D ED+++H   +DS  SN+ +D D  D+  + +E    D+ D+
Sbjct: 2398 ANREDSMNILDPEDEEEHTQEEDSSGSNEDED-DSQDEEEEEEEDEEDDQEDD 2449



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 11/112 (9%)

Query: 17   IPVKQADSGSSEEKQLYNKYPDAV--ATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDM 74
            I V ++    S+E  L ++ P  +  A+ L  +     N+L P+       E H   +D 
Sbjct: 2367 IIVSRSGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPE-----DEEEHTQEEDS 2421

Query: 75   D--DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD-ELVTDFP 123
               +ED+DD  D ++  + ++ DD +D D+  + DE    D S+ EL  D+P
Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQED-DEGEEGDEDDDDDGSEMELDEDYP 2472


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 58/259 (22%), Positives = 104/259 (40%), Gaps = 36/259 (13%)

Query: 20  KQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHM------DD 73
           K +DSGS  +    N    + A+    D  ++ +   P       ++S D         D
Sbjct: 19  KDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSD 78

Query: 74  MDDEDDDDHVDSQDSIDSNDSD--DVD----------DTDDSHQSD-ESHHSDE--SDEL 118
              E  D+  ++ +  D  D+D  DVD          D D+ H+SD  SHHS+   S++ 
Sbjct: 79  NHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKA 138

Query: 119 VTD---FPTDLPATEVFTPVVPTVDTYD---GRGDSVVYGLRSKSKKFRRPDIQYPDATD 172
            +D   +  +  + +     +   D  +   G  +  +       K     D + P  +D
Sbjct: 139 HSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSD 198

Query: 173 EDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLY 232
           ++     E E+ N   +  PVA D    +D + +  D  E  QL D+    +S  +    
Sbjct: 199 DERQQLSEEEKANSDDER-PVASD----NDDEKQNSDDEEQPQLSDEEKMQNSDDE---- 249

Query: 233 KRKANDESNEHSDVIDSQE 251
           + +A+DE + HSD  + Q+
Sbjct: 250 RPQASDEEHRHSDDEEEQD 268



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 8/76 (10%)

Query: 49  SQKQNLLAPQTLPSKSNESHDHMDDMDDED-----DDDHVDSQDSIDSNDSDDVDDTDDS 103
           S  +  +A      K N   +    + DE+     DD+   + D  +   SDD ++ D  
Sbjct: 212 SDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDE-EHRHSDDEEEQD-- 268

Query: 104 HQSDESHHSDESDELV 119
           H+S+ +  SD  DE++
Sbjct: 269 HKSESARGSDSEDEVL 284



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 43/217 (19%), Positives = 75/217 (34%), Gaps = 32/217 (14%)

Query: 71  MDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATE 130
           M+D+   D D   + +DS   +DSD   +   S  +     SD+ +   +  P++    E
Sbjct: 4   MEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSN---KE 60

Query: 131 VFTPVVPTVDTYDGRGDSVVYGL-----RSKSKKFRRPDIQYPDATDEDITSHMESEELN 185
           +F       D  +  G S   G      RS ++        + D    D+  H  SE   
Sbjct: 61  LFG------DDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSE--- 111

Query: 186 GAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKR--KANDESNEH 243
                        AP+D +  G  S   S   +      +H     + R  K++   +E 
Sbjct: 112 -------------APNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEK 158

Query: 244 SDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEE 280
               D +E ++ S E         E M   D + + +
Sbjct: 159 IQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQ 195


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 53/211 (25%), Positives = 81/211 (38%), Gaps = 36/211 (17%)

Query: 47  DPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDD--------DDHVDSQDSIDSNDSDDVD 98
           D     +L  P      S    D+ DD +  DD        DD+ D  ++ D N SDD D
Sbjct: 129 DDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN-SDDSD 187

Query: 99  DTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSK 158
             DD+       +SD+S +  +D  +D+P  +     VP     D   DS V    S   
Sbjct: 188 VPDDNSDDSSDDNSDDSSDDNSD-DSDVPDDKSDDSDVPD----DSSDDSDVPDDSS--- 239

Query: 159 KFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAP---SDWDSRGKDSYETSQ 215
                D + PD + +D  +  +S +            D  AP   SD      DS + S+
Sbjct: 240 ----DDSEAPDDSSDDSEAPDDSSD------------DSEAPDDSSDDSEAPDDSSDDSE 283

Query: 216 LDDQSAETHSHKQSRLYKRKANDESNEHSDV 246
             D S++            +A D+ ++ SDV
Sbjct: 284 ASDDSSDDSEASDDSSDDSEAPDDKSDDSDV 314



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 22/197 (11%)

Query: 56  APQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDES 115
           AP      S    D+ DD +  DD+         +S+DSD  DD  D    D S  S + 
Sbjct: 148 APDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDD 207

Query: 116 DELVTDFPTD-LPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDED 174
           +   +D P D    ++V        D  D   D       S++      D + PD + +D
Sbjct: 208 NSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD------SEAPDDSSDDSEAPDDSSDD 261

Query: 175 ITSHMESEELNGAYKAIPVAQDLNAP---SDWDSRGKDSYETSQLDDQSAETHSHKQSRL 231
             +  +S +            D  AP   SD      DS + S+  D S++       + 
Sbjct: 262 SEAPDDSSD------------DSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKS 309

Query: 232 YKRKANDESNEHSDVID 248
                 ++ ++ SDV D
Sbjct: 310 DDSDVPEDKSDDSDVPD 326



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 53/241 (21%), Positives = 83/241 (34%), Gaps = 25/241 (10%)

Query: 23  DSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDH 82
           D  S + +   +   D+ A   N D S+  +  +  +     N      D+ DD  DD+ 
Sbjct: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209

Query: 83  VDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTY 142
            DS    D +D  DV D D S  SD    S +  E   D   D  A +         D+ 
Sbjct: 210 DDSDVPDDKSDDSDVPD-DSSDDSDVPDDSSDDSEAPDDSSDDSEAPD---------DSS 259

Query: 143 DGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSD 202
           D           S++      D + PD + +D  S    +  + +  +   + D  AP  
Sbjct: 260 DD----------SEAPDDSSDDSEAPDDSSDD--SEASDDSSDDSEASDDSSDDSEAP-- 305

Query: 203 WDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSH 262
            D +  DS       D S     +         A D  NE     D +EL + +     H
Sbjct: 306 -DDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQH 364

Query: 263 E 263
           +
Sbjct: 365 D 365



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 58/265 (21%), Positives = 99/265 (37%), Gaps = 37/265 (13%)

Query: 23  DSGSSEEKQLYNKYPDAVATWLNPDPSQ-----KQNLLAPQTLPSKSNESHDHMDDMDDE 77
           DS S EE   + +    +    + D S      K  +  P  + S  +   D+ +D++  
Sbjct: 80  DSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVP 139

Query: 78  DDDDHVDSQDSIDSNDSDDVDD-TDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVV 136
           DD+         +S+DS+  DD +DDS   D++    E+ +  +D  +D+P         
Sbjct: 140 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD-DSDVPDDN------ 192

Query: 137 PTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQD 196
            + D+ D   D         S      D   PD   +D  S +  +  + +      + D
Sbjct: 193 -SDDSSDDNSDD--------SSDDNSDDSDVPDDKSDD--SDVPDDSSDDSDVPDDSSDD 241

Query: 197 LNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVS 256
             AP D       S ++   DD S ++ +   S       +D+S    D  D  E S  S
Sbjct: 242 SEAPDD------SSDDSEAPDDSSDDSEAPDDS-------SDDSEAPDDSSDDSEASDDS 288

Query: 257 REFHSHEFHSHEDMLVVDPKSKEED 281
            +       S +D    D KS + D
Sbjct: 289 SDDSEASDDSSDDSEAPDDKSDDSD 313


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 1/54 (1%)

Query: 64  SNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDS-HQSDESHHSDESD 116
           SNE  +  D+ +DE+DD+  +S DS   +DS+   DT+ S  + D+    DESD
Sbjct: 607 SNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD 660



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 16/55 (29%), Positives = 29/55 (52%)

Query: 62  SKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           ++  E  D  +D +D++DD+  DSQ   DSN   D + +++    D+     +SD
Sbjct: 608 NEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSD 662



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 17/55 (30%), Positives = 27/55 (49%)

Query: 63  KSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           + +E  D  DD DDE DD   +S  + +S+     ++ DD    DES    E ++
Sbjct: 613 EDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEK 667



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 15/51 (29%), Positives = 29/51 (56%)

Query: 67  SHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           S D  D  +DE++DD  + ++  + ++SDD     DS+   ++  S+E D+
Sbjct: 601 SKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 651



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 60  LPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           +PS S +S D  +D  +E+DD+  D +D  D    D   ++D + +SD     +E D+
Sbjct: 598 IPS-SKDSEDSNED--EEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 15/37 (40%), Positives = 23/37 (62%)

Query: 79  DDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDES 115
           D D   S+DS DSN+ ++ DD ++  + DE   SD+S
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDS 631



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 17/78 (21%), Positives = 35/78 (44%)

Query: 39  AVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVD 98
           AV+  +NP  +Q  +  A   +        D     D ED ++  +  D  +  + D+ D
Sbjct: 567 AVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDD 626

Query: 99  DTDDSHQSDESHHSDESD 116
           ++DDS    +S+   +++
Sbjct: 627 ESDDSQSESDSNSESDTE 644



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)

Query: 47   DPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVD----DTDD 102
            D  ++Q+ L   T P +         D DD+DDDD  D  D  D ++ D  D     TD 
Sbjct: 1273 DLGEEQHPLGTPT-PGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDI 1331

Query: 103  SHQSDESHHSDESDEL 118
                DE   +   +EL
Sbjct: 1332 CEDEDEGDQAASVEEL 1347



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 45  NPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDS---IDSNDSDDV-DDT 100
           N + S+ Q L A              M+   + D D    S  S   I S+DSDD+ +D 
Sbjct: 213 NQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDE 272

Query: 101 DDSHQSDESHHSDESD 116
           ++  QS E    D+SD
Sbjct: 273 EEEDQSIEESEDDDSD 288



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 13/50 (26%), Positives = 25/50 (50%)

Query: 76  DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTD 125
           D D     DS+DS +  + DD ++ ++  + DES  S    +  ++  T+
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTE 644



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 20/98 (20%), Positives = 37/98 (37%), Gaps = 4/98 (4%)

Query: 20  KQADSGSSEEK----QLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMD 75
           K   SG    K    Q  N+  DA    +     +K+ + +     S S  S D   +  
Sbjct: 201 KSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGI 260

Query: 76  DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSD 113
              D D ++  +  +    ++ +D D   +S+  H S+
Sbjct: 261 SSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSN 298


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 62/303 (20%), Positives = 122/303 (40%), Gaps = 45/303 (14%)

Query: 26  SSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVD- 84
           SS E++ Y K  D V        + K+  +  + L    N S+D   D D++  D +++ 
Sbjct: 404 SSIEREEYGKLFDFV--------NAKKLNIKNRGLKEGMNPSYDEYADSDEDQHDAYLER 455

Query: 85  --SQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTY 142
              +  I   +++D  D D   ++DES +  E +E V +   D  A+   +      D  
Sbjct: 456 MKEEGKIREENANDSSD-DSGEETDESFNPGEEEEDVAE-EFDSNASASSSSNEGDSDRD 513

Query: 143 DGRGDSVVYGLRSKSKKFRRPDIQY-----PDATDEDITSHM-----ESEELNGAYKAIP 192
           + +   +     +K +K R+  ++      P+A    ++++M       E++   +  I 
Sbjct: 514 EKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGIS 573

Query: 193 VAQDLNAPS-------------DWDSRGKDS---YETSQLDDQSAETHSHKQSRLYKRKA 236
           +  DL+  +             +WD + +D+   YE +  + +     S K+ +  K+K 
Sbjct: 574 IT-DLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKK 632

Query: 237 NDESNEHSDVIDSQELSK-----VSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHE 291
                E          SK     +S  F S EF S ++    + KSK++ +  +     E
Sbjct: 633 VKVKMEKKSTPSRGSSSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEE 692

Query: 292 LDS 294
           L S
Sbjct: 693 LAS 695


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/71 (29%), Positives = 35/71 (49%)

Query: 44   LNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDS 103
            L P  S +Q   + Q    K ++      D ++EDDD++    +  + ++ DD DD DD+
Sbjct: 1920 LGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDT 1979

Query: 104  HQSDESHHSDE 114
               DE   S+E
Sbjct: 1980 GMGDEGEDSNE 1990



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 14/52 (26%), Positives = 30/52 (57%)

Query: 65   NESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
            +E ++  ++ DD+D+DD     +  DSN+     D +D +++D++   D +D
Sbjct: 1962 HEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTD 2013



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 7/54 (12%)

Query: 69   DHMDDMDDEDD----DDHVDSQD---SIDSNDSDDVDDTDDSHQSDESHHSDES 115
            D  DD DDEDD    D+  DS +   S D ND  + DD +    +D    ++ES
Sbjct: 1968 DEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEES 2021



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 54   LLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSD-DVDDTDDSHQSDESHHS 112
            L + Q   + S +     DD+   D DD  +  D  D    D + D+ DD    D++   
Sbjct: 1923 LQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMG 1982

Query: 113  DESDE 117
            DE ++
Sbjct: 1983 DEGED 1987


>gi|7661622 hypothetical protein LOC25906 [Homo sapiens]
          Length = 121

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 6/69 (8%)

Query: 49  SQKQNLLAPQTLPSKSNESHDHMDDMDDE-DDDDHVDSQDSIDSNDSDDVDDTDDSHQSD 107
           ++K N L P   P+      +H DD ++E D+DD    +DS D  D  D+D+ +D ++S 
Sbjct: 45  AEKDNNLVPIGKPAS-----EHYDDEEEEDDEDDEDSEEDSEDDEDMQDMDEMNDYNESP 99

Query: 108 ESHHSDESD 116
           +    +E D
Sbjct: 100 DDGEVNEVD 108


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 3/51 (5%)

Query: 66  ESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESD 116
           E  D  DD DDEDDDD  D ++  +  + DD DDT+D   +D+ +  D  D
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEE-EEEEEDDDDDTEDF--ADQENLPDPQD 182



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 63  KSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSD----ESHHSDESDEL 118
           + ++  D  DD DD+D++D  + ++  + +D D  D  D  +  D      H S    + 
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQSPSKTDH 194

Query: 119 VT-----DFPTDLP 127
           +T     D P D P
Sbjct: 195 LTEKAYSDTPRDFP 208



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 11/34 (32%), Positives = 16/34 (47%)

Query: 84  DSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           D  +  D  D DD +D DD    +E    +E D+
Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDD 165


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 10/67 (14%)

Query: 61  PSKSNESHDHMDDMDDEDDDDHVDSQDSIDSND----------SDDVDDTDDSHQSDESH 110
           PS  ++ H+  DD DD+DDDD  D   SI+              +D D +D  H  D SH
Sbjct: 236 PSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSH 295

Query: 111 HSDESDE 117
                +E
Sbjct: 296 RHRSHEE 302



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 58/242 (23%), Positives = 88/242 (36%), Gaps = 42/242 (17%)

Query: 67  SHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDL 126
           SH H    +D++DDD V ++    ++   D    +    S E HH       V D     
Sbjct: 294 SHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHH------VPDHRHQG 347

Query: 127 PATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPD--ATDEDITSHMESEEL 184
              E     V T   + G    V +GL  + ++     +Q+    A+ +      + E+ 
Sbjct: 348 HRDEEEDEDVSTERWHQG-PQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDF 406

Query: 185 NGAYKA-IPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEH 243
              YK  +P       P     R +D   +++L  Q+    SH+QS        DE   H
Sbjct: 407 QDEYKTEVPHHHHHRVP-----REEDEEVSAELGHQAP---SHRQSH------QDEETGH 452

Query: 244 SDVIDSQELSK-------VSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSAS 296
                 +E+S        V    H  +  S E+      K KEED       SHE D  S
Sbjct: 453 GQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEE------KEKEEDPG-----SHEEDDES 501

Query: 297 SE 298
           SE
Sbjct: 502 SE 503



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 21/63 (33%)

Query: 67  SHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSD--------ESDEL 118
           SH H    +D+DDDD             DD DD DD   S E  H          E DE 
Sbjct: 237 SHRHQGHEEDDDDDD-------------DDDDDDDDDDVSIEYRHQAHRHQGHGIEEDED 283

Query: 119 VTD 121
           V+D
Sbjct: 284 VSD 286


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 15/53 (28%), Positives = 29/53 (54%)

Query: 65  NESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDE 117
           +E +D   D D+ED++   + ++ I+  D DD +D +D    +E    +E +E
Sbjct: 111 SEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 18/73 (24%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 46  PDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVD-SQDSIDSNDSDDVDDTDDSH 104
           P P +K   +   +      +  D  +DMD++++D+  + S+D+ +  D D+ D+  D  
Sbjct: 71  PAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDRE 130

Query: 105 QSDESHHSDESDE 117
           + +E    DE D+
Sbjct: 131 EEEEIEEEDEDDD 143



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 26/128 (20%), Positives = 51/128 (39%), Gaps = 14/128 (10%)

Query: 63  KSNESHDHMDDMDDEDDDDHVDSQ---------DSIDSNDSDDVDDTDDSHQSDESHHSD 113
           + +E  ++ +D D+  D+D  D +         +  D +D +D +D +D  + +E    +
Sbjct: 103 EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162

Query: 114 ESDELVTDFPTDLPATEVFTPVVP---TVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDA 170
           E +E   D   +   T +           D YD   + V   L +  K     D  Y   
Sbjct: 163 EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK--IAEDAAYRAR 220

Query: 171 TDEDITSH 178
           T+ ++ S+
Sbjct: 221 TESEMNSN 228



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 42/213 (19%), Positives = 74/213 (34%), Gaps = 51/213 (23%)

Query: 93  DSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYG 152
           DS  VD+ DDS  +++    +E +        D P  E         D  D  GD     
Sbjct: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE---------DEEDEEGD----- 128

Query: 153 LRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYE 212
            R + ++    D +  D   ED+    E EE                        ++  E
Sbjct: 129 -REEEEEIEEED-EDDDEDGEDVEDEEEEEE------------------------EEEEE 162

Query: 213 TSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDS------QELSKVS-----REFHS 261
             + +++  + + H    +   + +D +N+  D  D         L K++     R    
Sbjct: 163 EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTE 222

Query: 262 HEFHSHEDMLVVDPKSKEEDKHLKFRISHELDS 294
            E +S+    + D   K E+   K  +S +LDS
Sbjct: 223 SEMNSNTSNSLEDDSDKNENLGRKSELSLDLDS 255


>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 53  NLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHS 112
           N L    +P   +E     DD DD+D D+  +  + ID  D D+ ++ +D  + +E    
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 113 DESDE 117
           +  D+
Sbjct: 298 EGEDD 302


>gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 53  NLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHS 112
           N L    +P   +E     DD DD+D D+  +  + ID  D D+ ++ +D  + +E    
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 113 DESDE 117
           +  D+
Sbjct: 298 EGEDD 302


>gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 17/65 (26%), Positives = 31/65 (47%)

Query: 53  NLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHS 112
           N L    +P   +E     DD DD+D D+  +  + ID  D D+ ++ +D  + +E    
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 113 DESDE 117
           +  D+
Sbjct: 298 EGEDD 302


>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
          Length = 1812

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 2/125 (1%)

Query: 18  PVKQADSGSSEEKQLYNK-YPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMD- 75
           PV    SG  EE   + + Y + ++   N  P + Q     +    +  E  +  DD+D 
Sbjct: 198 PVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDV 257

Query: 76  DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPV 135
           +E++D+  D + ++DS   ++ +D ++  + DE    D+  E ++     +   E  T  
Sbjct: 258 EEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFK 317

Query: 136 VPTVD 140
            P  D
Sbjct: 318 YPNFD 322


>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
          Length = 1147

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 2/125 (1%)

Query: 18  PVKQADSGSSEEKQLYNK-YPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMD- 75
           PV    SG  EE   + + Y + ++   N  P + Q     +    +  E  +  DD+D 
Sbjct: 198 PVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDV 257

Query: 76  DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPV 135
           +E++D+  D + ++DS   ++ +D ++  + DE    D+  E ++     +   E  T  
Sbjct: 258 EEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFK 317

Query: 136 VPTVD 140
            P  D
Sbjct: 318 YPNFD 322


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 47/234 (20%), Positives = 93/234 (39%), Gaps = 27/234 (11%)

Query: 65   NESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPT 124
            NES    +  +   +DD  + ++ +D+      DD D         HS+E  + V +   
Sbjct: 4933 NESQSPQEPEEGPSEDDKAEGEEEMDTG----ADDQDGDAAQHPEEHSEEQQQSVEEKDK 4988

Query: 125  DL--------PATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDIT 176
            +         PA + F P        + R DS         +   R +      T  +  
Sbjct: 4989 EADEEGGENGPADQGFQP-----QEEEEREDSDTE--EQVPEALERKEHASCGQTGVENM 5041

Query: 177  SHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKA 236
             + ++ EL GA       ++ +     D+   + +E++ +   +++ H+ K ++ +KRK 
Sbjct: 5042 QNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP 5101

Query: 237  NDESNEHSDVIDSQELSKVSREFHSHEFHSH-EDMLVVDPKSKEED----KHLK 285
                NE S + D  E  +V +   + +  SH E      P+++ ED    +H+K
Sbjct: 5102 GQADNERS-MGDHNE--RVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIK 5152



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 44/239 (18%), Positives = 92/239 (38%), Gaps = 38/239 (15%)

Query: 47   DPSQKQNLLAPQTLPSKSNESHDHMDD---MDDEDDDDHVDSQDS--------IDSNDSD 95
            DP  K ++         S +    M D    + E+DD+  DS+          ++  ++D
Sbjct: 4713 DPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEAD 4772

Query: 96   DVDDT---DDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYG 152
             +D+    DD  + DE    ++++E      T     E  + +V   D  D    +    
Sbjct: 4773 KLDERLWGDDDEEEDEEEEDNKTEE------TGPGMDEEDSELVAKDDNLDSGNSN---- 4822

Query: 153  LRSKSKKFRRPDIQYPDATD----EDITSHM---------ESEELNGAYKAIPVAQDLNA 199
             + KS++ ++ + +  +A D    ED  +           E +  +G  + +P  + L+ 
Sbjct: 4823 -KDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDL 4881

Query: 200  PSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSRE 258
            P D +   +D       D++  E  +  + +    +A  E+ E  +    Q  S+  +E
Sbjct: 4882 PDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQE 4940



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 45/207 (21%), Positives = 77/207 (37%), Gaps = 17/207 (8%)

Query: 76   DEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPV 135
            DE+D + V   D++DS +S+      D  +  E   +D+  +        +   +     
Sbjct: 4803 DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE-- 4860

Query: 136  VPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQ 195
               VD Y G  + V      + +    PD    D+ D++     ++EE           +
Sbjct: 4861 -NEVDPYHGNQEKV-----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEK 4914

Query: 196  DLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKV 255
               A  + + RG+   ET Q + QS +      S   K +  +E +  +D  D       
Sbjct: 4915 PEEAGHEAEERGET--ETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQ-- 4970

Query: 256  SREFHSHEFHSHEDMLVVDPKSKEEDK 282
                H  E HS E    V+ K KE D+
Sbjct: 4971 ----HPEE-HSEEQQQSVEEKDKEADE 4992


>gi|31543091 MAK16 homolog [Homo sapiens]
          Length = 300

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 8/74 (10%)

Query: 55  LAPQTLPSKSNESHDHMDDMDDEDD--------DDHVDSQDSIDSNDSDDVDDTDDSHQS 106
           L  Q   S S+++ +  DD DDE+D        D  VD  D  D  D D +D + D  Q 
Sbjct: 190 LEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDEDQD 249

Query: 107 DESHHSDESDELVT 120
            +S   +E ++ ++
Sbjct: 250 GKSSSEEEEEKALS 263


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,309,761
Number of Sequences: 37866
Number of extensions: 599349
Number of successful extensions: 6194
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 3323
Number of HSP's gapped (non-prelim): 1518
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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