Guide to the Human Genome
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Name: SPP1 Sequence: fasta or formatted (314aa) NCBI GI: 91206462
Description:

secreted phosphoprotein 1 isoform a

Referenced in:

Bone and Related Tissues
Protein Composition and Structure

Other entries for this name:
alt prot [300aa] secreted phosphoprotein 1 isoform b
alt prot [287aa] secreted phosphoprotein 1 isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         16           1
 C cysteine            1.0          3           1
 D aspartate          15.3         48           4
 E glutamate           8.6         27           2
 F phenylalanine       2.5          8           1
 G glycine             2.2          7           1
 H histidine           5.1         16           2
 I isoleucine          3.2         10           1
 K lysine              6.1         19           2
 L leucine             5.7         18           2
 M methionine          1.6          5           1
 N asparagine          3.8         12           1
 P proline             4.8         15           1
 Q glutamine           4.5         14           1
 R arginine            3.2         10           2
 S serine             13.4         42           2
 T threonine           4.8         15           1
 V valine              6.1         19           2
 W tryptophan          0.6          2           1
 Y tyrosine            2.5          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   secreted phosphoprotein 1 isoform a 
SPP1                  0.940   secreted phosphoprotein 1 isoform b 
SPP1                  0.883   secreted phosphoprotein 1 isoform c 
DSPP                  0.074   dentin sialophosphoprotein preproprotein 
LEO1                  0.040   Leo1, Paf1/RNA polymerase II complex component, homo...
MTERFD2               0.039   MTERF domain containing 2 
ATAD2                 0.039   ATPase family, AAA domain containing 2 
HUWE1                 0.037   HECT, UBA and WWE domain containing 1 
DMP1                  0.037   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
UBTF                  0.036   upstream binding transcription factor, RNA polymera...
UBTF                  0.036   upstream binding transcription factor, RNA polymera...
UBTF                  0.036   upstream binding transcription factor, RNA polymerase...
MDN1                  0.036   MDN1, midasin homolog 
DMP1                  0.036   dentin matrix acidic phosphoprotein 1 isoform 2 pre...
NCL                   0.034   nucleolin 
ACRC                  0.032   ACRC protein 
MYT1L                 0.031   myelin transcription factor 1-like 
BAZ2B                 0.031   bromodomain adjacent to zinc finger domain, 2B [Homo...
CASQ2                 0.028   cardiac calsequestrin 2 precursor 
HRC                   0.028   histidine rich calcium binding protein precursor [Hom...
CASZ1                 0.026   castor homolog 1, zinc finger isoform a 
IWS1                  0.026   IWS1 homolog 
MYST4                 0.026   MYST histone acetyltransferase (monocytic leukemia)...
SSRP1                 0.024   structure specific recognition protein 1 
ZBTB7C                0.024   zinc finger and BTB domain containing 7C 
LOC646817             0.024   PREDICTED: similar to SET translocation 
LOC646817             0.024   PREDICTED: similar to SET translocation 
LOC646817             0.024   PREDICTED: similar to SET translocation 
NRD1                  0.024   nardilysin isoform b 
NRD1                  0.024   nardilysin isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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