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Search of human proteins with 4759114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
(487 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 981 0.0
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 217 2e-56
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 199 4e-51
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 190 2e-48
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 186 4e-47
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 176 3e-44
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 158 9e-39
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 149 7e-36
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 131 1e-30
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 114 2e-25
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 108 1e-23
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 108 1e-23
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 108 1e-23
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 107 3e-23
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 92 8e-19
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 85 2e-16
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 78 2e-14
gi|4503847 solute carrier family 37 (glucose-6-phosphate transpo... 37 0.040
gi|217416366 major facilitator superfamily domain containing 9 [... 37 0.053
gi|225703102 major facilitator superfamily domain containing 10 ... 35 0.15
gi|225703104 major facilitator superfamily domain containing 10 ... 35 0.15
gi|166064062 tumor suppressing subtransferable candidate 5 [Homo... 33 0.58
gi|166064060 tumor suppressing subtransferable candidate 5 [Homo... 33 0.58
gi|53828692 olfactory receptor, family 4, subfamily K, member 5 ... 32 1.7
gi|53933201 olfactory receptor, family 5, subfamily B, member 2 ... 31 2.2
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo... 31 2.9
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo... 31 2.9
gi|50080195 olfactory receptor, family 5, subfamily A, member 2 ... 31 2.9
gi|31542731 major facilitator superfamily domain containing 7 [H... 31 2.9
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 30 3.8
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 981 bits (2537), Expect = 0.0
Identities = 487/487 (100%), Positives = 487/487 (100%)
Query: 1 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG 60
MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG
Sbjct: 1 MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIG 60
Query: 61 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL 120
WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL
Sbjct: 61 WIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLL 120
Query: 121 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL 180
PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL
Sbjct: 121 PGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL 180
Query: 181 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS 240
FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS
Sbjct: 181 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDS 240
Query: 241 TTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPF 300
TTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPF
Sbjct: 241 TTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPF 300
Query: 301 FYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQ 360
FYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQ
Sbjct: 301 FYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQ 360
Query: 361 NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRN 420
NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRN
Sbjct: 361 NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRN 420
Query: 421 STVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAE 480
STVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAE
Sbjct: 421 STVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAE 480
Query: 481 RWKNSLT 487
RWKNSLT
Sbjct: 481 RWKNSLT 487
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 217 bits (553), Expect = 2e-56
Identities = 147/482 (30%), Positives = 229/482 (47%), Gaps = 60/482 (12%)
Query: 12 TKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRF 71
T DGGWGWMIV FLV + +T+ +IFFV FQ F Q WI SI+ +
Sbjct: 10 TSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTM 69
Query: 72 CAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQV 131
PL +++ + L + +LG + + G ++SS+ATS+ L +T+G+L GLG A Y
Sbjct: 70 LCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSP 129
Query: 132 AAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVP 190
A + KYF +R AL+ IA SG G+ TF+LAP + LI+ + W GAL++ G LNL
Sbjct: 130 AIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCV 189
Query: 191 SSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSK 250
L+RPI +K ++ + PE + H T++ IK + P
Sbjct: 190 CGALMRPITLKEDHTT-------------PE----QNHVCRTQKEDIKRVS------PYS 226
Query: 251 NLTVSQNQSEEFYNGPNRNRLLLKSD----EESDKVISWSCKQLFDISLFRNPFFYIFTW 306
+LT Q+ LL SD S +++ C LF
Sbjct: 227 SLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLF--------------- 271
Query: 307 SFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKY 366
+LV A ++G+ A++L+S+ G+++ + I GW+ D+ +K Y
Sbjct: 272 -------------VYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNY 318
Query: 367 HYHKSYLI---LCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTV 423
Y YL + G+ L P+ + PLL+ ++ F F G Y+ LI V ++ +++
Sbjct: 319 QY-VCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSL 377
Query: 424 NRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWK 483
+ LG+ F + L PPIAG L D T +Y +F G + SSV F L +R +
Sbjct: 378 SSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMR 437
Query: 484 NS 485
+
Sbjct: 438 KT 439
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 199 bits (507), Expect = 4e-51
Identities = 141/485 (29%), Positives = 234/485 (48%), Gaps = 42/485 (8%)
Query: 15 LDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAG 74
+DGGW WM+V+ F V++ +MG + V + EEF + W+ S+ + G
Sbjct: 28 IDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVG 87
Query: 75 PLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAV 134
P + + + G + T+I+G V + G+++S++A ++ +L +T G+ GLGS Y A V
Sbjct: 88 PFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVV 147
Query: 135 VTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSM 193
+ +YF+KR AL+ ++ +G G TFL+ K+L Y W A+++ GA++LNL
Sbjct: 148 MVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGA 207
Query: 194 LLRPIHI-KSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNL 252
L+RP+ K+ N+ G KD G AH+TE+ + + + T +K G
Sbjct: 208 LMRPLSPGKNPNDPGEKD------VRGLPAHSTES----VKSTGQQGRTEEKDGGLGNEE 257
Query: 253 TVSQNQSEEFYN--GPNRNRLLLKSDEESDKVISWSCKQL---FD---------ISLFRN 298
T+ Q++E + G +N L+ K +SW ++ F+ SLF N
Sbjct: 258 TLCDLQAQECPDQAGHRKNMCALR----ILKTVSWLTMRVRKGFEDWYSGYFGTASLFTN 313
Query: 299 PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGI-DIMDASYLVSVAGILETVSQIISGWV 357
F F + L + ++ IP HL + + D L S+ I+ ++I G +
Sbjct: 314 RMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVI 373
Query: 358 ADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTY----TICFAI-FAGGYLALILP 412
AD I + + +L T +L+ PL+ TY IC I F+ GY +L+
Sbjct: 374 ADLPCISVW----NVFLLANFTLVLS--IFILPLMHTYAGLAVICALIGFSSGYFSLMPV 427
Query: 413 VLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVS 472
V DL + G+ G++ L GPP AGW+YD TQ Y+ SFY G+ Y++ +
Sbjct: 428 VTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILF 487
Query: 473 FFFVP 477
P
Sbjct: 488 LLIQP 492
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 190 bits (483), Expect = 2e-48
Identities = 129/487 (26%), Positives = 223/487 (45%), Gaps = 49/487 (10%)
Query: 13 KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72
K+ DGGWGW+IV FL G + ++ + + F + W+GS+ S +
Sbjct: 5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64
Query: 73 AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132
A P+ ++ G + +I F+V GG ++SS+A +I FL + G++ GLG LY
Sbjct: 65 ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124
Query: 133 AVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191
+T +YF R L+ + +G + F+ A + L++ Y G L++ GA+ALN++
Sbjct: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184
Query: 192 SMLLRPIHIKS-------------ENNSGIKDKGSSLSAH---GPEAHATETHCHETEES 235
L+RP+ + S +KG +L + +++++E C
Sbjct: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKC----RI 240
Query: 236 TIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLF---- 291
T+ + ++ L KN TV+ + E Y K E+ ++ CKQL
Sbjct: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYK--------KKVAEQ-----TYFCKQLAKRKW 287
Query: 292 ---------DISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMD-ASYLVS 341
++LF+N F + LL + F P+ + A++ + + L+S
Sbjct: 288 QLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLIS 347
Query: 342 VAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAI 401
+ GI+ V +++ G +AD WI + + + LI+ G+ P A ++ L +
Sbjct: 348 IIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGF 407
Query: 402 FAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYF 461
G + ++ V + G+ FFAG+ GPPI GW YD+TQTY+ +FYF
Sbjct: 408 LTGNW-SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYF 466
Query: 462 SGICYLL 468
SG C LL
Sbjct: 467 SGFCVLL 473
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 186 bits (472), Expect = 4e-47
Identities = 133/480 (27%), Positives = 228/480 (47%), Gaps = 19/480 (3%)
Query: 2 LKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGW 61
LK K YT+ DGGWGW + + FF V VF G+ KTF +FF + F ++ +I W
Sbjct: 6 LKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISW 65
Query: 62 IGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLP 121
I SI + + PL ++ + G + +LG +V+ G + +S++ + + V +G++
Sbjct: 66 IISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIIS 125
Query: 122 GLGSAFLYQVAAVVTTKYFKKRLALSTAIARSG-MGLTFLLAPFTKFLIDLYDWTGALIL 180
GLG F + + ++YF KR ++ TA+A +G F AP L + W +L+
Sbjct: 126 GLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLF 185
Query: 181 FGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEES-TIKD 239
G + LN+V LLRPI I+ + I + + A + E E++ T D
Sbjct: 186 VGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQ---------YMLENEKTRTSID 236
Query: 240 STTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLK-SDEESDKVISWSCKQLFDISLFRN 298
S L + V + + E + ++L+K S S+K L D S+ +
Sbjct: 237 SIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKK-----APLLDFSILKE 291
Query: 299 PFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVA 358
F + L + L +F P+ +++ +LGID A++L+S I E +I +G+V
Sbjct: 292 KSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVL 351
Query: 359 DQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLV--D 416
++ I+K + +IL ++ AT F LM+ +I F G +P+L D
Sbjct: 352 NREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDD 411
Query: 417 LCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFV 476
+ ++ G+ F +A L+GPP+AG L D ++ Y+ +FY L++V V
Sbjct: 412 VVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALV 471
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 176 bits (447), Expect = 3e-44
Identities = 125/461 (27%), Positives = 211/461 (45%), Gaps = 61/461 (13%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
DGGWGW++V F+ F K +FF Q+ F T +I WI SIM ++ + GP
Sbjct: 15 DGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGP 74
Query: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
+ +++ + G + I G + G +++S+++S+ L +TMG + GLG AF Q A +
Sbjct: 75 VSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTI 134
Query: 136 TTKYFKKRLALSTAIARSGMGLTFL--LAPFTKFLIDLYDWTGALILFGAIALNLVPSSM 193
KYF ++ ++ +A +G + FL LAPF ++L + + W G+ ++ G++ LN +
Sbjct: 135 IGKYFYRKRPMANGLAMAGSPV-FLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
Query: 194 LLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLT 253
L+RP+ GP T +S K T+ P K T
Sbjct: 194 LMRPL--------------------GPN--------QTTSKSKNKTGKTEDDSSPKKIKT 225
Query: 254 VSQNQSEEFYNGPNRNRLLLKSDEESDKVISW-SCKQLFDISLFRNPFFYIFTWSFLLSQ 312
K +W + D SLF++ F I+ ++
Sbjct: 226 ---------------------------KKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMF 258
Query: 313 LAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIK-KYHYHKS 371
L +F P L AK GID A++L+SV ++ ++ G +A+ +I+ + Y S
Sbjct: 259 LGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFS 318
Query: 372 YLILC-GITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLA 430
+ I+ G+ +LL PLA + L+ Y + F + G +++ L+DL + +GL
Sbjct: 319 FAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLV 378
Query: 431 SFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSV 471
+ VL GPP+AG L D T Y + G + +SV
Sbjct: 379 TIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASV 419
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 158 bits (400), Expect = 9e-39
Identities = 109/462 (23%), Positives = 204/462 (44%), Gaps = 41/462 (8%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
DGGWGW +VI F+ F K+ +FF + F T+ ++ WI SIM ++ + GP
Sbjct: 15 DGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGP 74
Query: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
+ +I+ + G + I+G + G + +S+ ++ L V +G++ GLG AF A +
Sbjct: 75 ISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTM 134
Query: 136 TTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
KYF KR L+ +A +G + LAP + ++ W G+ ++ G + LN + L
Sbjct: 135 IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGAL 194
Query: 195 LRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTV 254
+RPI K K K +SL G + H T+
Sbjct: 195 MRPIGPKPTKAGKDKSK-ASLEKAGKSGVKKDLHDANTD--------------------- 232
Query: 255 SQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLA 314
L+ + ++ + + + Q D++LF + F ++ ++
Sbjct: 233 ----------------LIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFG 276
Query: 315 YFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKK--YHYHKSY 372
F P L + K+ +++L+S+ ++ V++ G VA+ I+ ++ +
Sbjct: 277 LFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAAS 336
Query: 373 LILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASF 432
++ G+ ++LAPL+TT+ Y F G +++ L+DL + +GL +
Sbjct: 337 VVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTI 396
Query: 433 FAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFF 474
VL GPP+ G L D Y +++ G+ ++S + F
Sbjct: 397 VECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLF 438
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 149 bits (375), Expect = 7e-36
Identities = 111/459 (24%), Positives = 198/459 (43%), Gaps = 50/459 (10%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
DGGWGW+++ F+V F G K ++FF +F+ W+ SIM ++ + GP
Sbjct: 14 DGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGP 73
Query: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
+ +I+ G + + G + + G +++S+AT + L +T G+L GLG A +Q + ++
Sbjct: 74 VSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIM 133
Query: 136 TTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
YF++R L+ +A +G + L+P + L++ + W G +L G + L+ +
Sbjct: 134 LGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAV 193
Query: 195 LRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTV 254
+RP GP + ++ AGL + +
Sbjct: 194 MRP-------------------PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASP 234
Query: 255 SQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLA 314
R RLL D+++ + F ++ + L L
Sbjct: 235 RVRP---------RRRLL-------------------DLAVCTDRAFAVYAVTKFLMALG 266
Query: 315 YFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKY--HYHKSY 372
F+P LV AK G+ DA++L+S+ G ++ V++ G +A ++ + +
Sbjct: 267 LFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLA 326
Query: 373 LILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASF 432
L+ G+T+L + A ++ L+ + + F + G AL VL+ LGL
Sbjct: 327 LLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLL 386
Query: 433 FAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSV 471
AVL GPP AG L D + Y FY +G L+ V
Sbjct: 387 VEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGV 425
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 131 bits (330), Expect = 1e-30
Identities = 71/211 (33%), Positives = 121/211 (57%), Gaps = 2/211 (0%)
Query: 12 TKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRF 71
T+ DGGWGW++V+ F + V G+ ++F +FFV F FE + ++ WI SI +++
Sbjct: 5 TEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQ 64
Query: 72 CAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQV 131
P+ + + G + + G + G L++S+ATS+ L +++GLL G G A +
Sbjct: 65 FGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAP 124
Query: 132 AAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVP 190
+ YF +R +L+T +A +G+GL +F APF ++L+ Y W G+L+L A++L+LV
Sbjct: 125 TLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVA 184
Query: 191 SSMLLRPIHIKSENN-SGIKDKGSSLSAHGP 220
LLRP + + G + + +SL HGP
Sbjct: 185 CGALLRPPSLAEDPAVGGPRAQLTSLLHHGP 215
Score = 83.6 bits (205), Expect = 4e-16
Identities = 54/176 (30%), Positives = 83/176 (47%), Gaps = 1/176 (0%)
Query: 294 SLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQII 353
SL + F +T + L YFIP HLVA + L D + A++L+SV I + V +++
Sbjct: 209 SLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVV 268
Query: 354 SGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPV 413
SGW+ D + L G++ L P+A L+ + + +G L V
Sbjct: 269 SGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSV 328
Query: 414 LVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLS 469
L +L + LGL + L GPP++G+L D T Y SF +G +LLS
Sbjct: 329 LPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAG-AFLLS 383
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 114 bits (285), Expect = 2e-25
Identities = 56/184 (30%), Positives = 103/184 (55%), Gaps = 1/184 (0%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
DGGWGW++ F +N G+ ++ + F E F+ +++ WI ++ +++ A P
Sbjct: 34 DGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASP 93
Query: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
+ + + G + ++G + + G++ S++A+ + L + +GLL G G A ++ A
Sbjct: 94 VGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGT 153
Query: 136 TTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
++YF +R L+ +A +G G + LLAP + L+D + W GAL+L GAI L+L P L
Sbjct: 154 LSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGAL 213
Query: 195 LRPI 198
L P+
Sbjct: 214 LLPL 217
Score = 78.2 bits (191), Expect = 2e-14
Identities = 56/195 (28%), Positives = 85/195 (43%), Gaps = 9/195 (4%)
Query: 293 ISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQI 352
+SLF F IF L YF+P HL A G+ A+ +V+VA + + +++
Sbjct: 236 LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARL 295
Query: 353 ISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTF--------PLLMTYTICFAIFAG 404
+ GW+ADQ W+ + L G+ + L PLL + + + AG
Sbjct: 296 VCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAA-AVAYGLSAG 354
Query: 405 GYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGI 464
Y L+ VL L V + GL + L GPP++G+L D T + SF SG
Sbjct: 355 SYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS 414
Query: 465 CYLLSSVSFFFVPLA 479
L S + +P A
Sbjct: 415 LILSGSFIYIGLPRA 429
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 108 bits (270), Expect = 1e-23
Identities = 55/196 (28%), Positives = 101/196 (51%), Gaps = 1/196 (0%)
Query: 13 KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72
K DGGWGW ++ F++ F K ++FF +EF WI SI+ ++ +
Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
Query: 73 AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132
GPL ++ + G + ++G + G + +S+ SI + +T G++ GLG A +Q +
Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
Query: 133 AVVTTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191
++ +YF KR ++ +A +G + L+P + L D Y W G ++ G + LN
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193
Query: 192 SMLLRPIHIKSENNSG 207
+ L+RP+ + ++ SG
Sbjct: 194 AALMRPLVVTAQPGSG 209
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
++L D+S+FR+ F ++ + + L F+P +V+ AK LG+ A++L+++ G ++
Sbjct: 215 RRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID 274
Query: 348 TVSQIISGWVADQNWIKKY--HYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
++ +G+VA ++ Y + + G+ +L A + L+ + I F I G
Sbjct: 275 IFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGM 334
Query: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
AL VL+ + + +GL +AVL GPP G L D T Y F +G
Sbjct: 335 VGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAE 394
Query: 466 YLLSSV 471
L SS+
Sbjct: 395 VLTSSL 400
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 108 bits (270), Expect = 1e-23
Identities = 55/196 (28%), Positives = 101/196 (51%), Gaps = 1/196 (0%)
Query: 13 KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72
K DGGWGW ++ F++ F K ++FF +EF WI SI+ ++ +
Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
Query: 73 AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132
GPL ++ + G + ++G + G + +S+ SI + +T G++ GLG A +Q +
Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
Query: 133 AVVTTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191
++ +YF KR ++ +A +G + L+P + L D Y W G ++ G + LN
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193
Query: 192 SMLLRPIHIKSENNSG 207
+ L+RP+ + ++ SG
Sbjct: 194 AALMRPLVVTAQPGSG 209
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
++L D+S+FR+ F ++ + + L F+P +V+ AK LG+ A++L+++ G ++
Sbjct: 215 RRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID 274
Query: 348 TVSQIISGWVADQNWIKKY--HYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
++ +G+VA ++ Y + + G+ +L A + L+ + I F I G
Sbjct: 275 IFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGM 334
Query: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
AL VL+ + + +GL +AVL GPP G L D T Y F +G
Sbjct: 335 VGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAE 394
Query: 466 YLLSSV 471
L SS+
Sbjct: 395 VLTSSL 400
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 108 bits (270), Expect = 1e-23
Identities = 55/196 (28%), Positives = 101/196 (51%), Gaps = 1/196 (0%)
Query: 13 KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72
K DGGWGW ++ F++ F K ++FF +EF WI SI+ ++ +
Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73
Query: 73 AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132
GPL ++ + G + ++G + G + +S+ SI + +T G++ GLG A +Q +
Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133
Query: 133 AVVTTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191
++ +YF KR ++ +A +G + L+P + L D Y W G ++ G + LN
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193
Query: 192 SMLLRPIHIKSENNSG 207
+ L+RP+ + ++ SG
Sbjct: 194 AALMRPLVVTAQPGSG 209
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 2/186 (1%)
Query: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
++L D+S+FR+ F ++ + + L F+P +V+ AK LG+ A++L+++ G ++
Sbjct: 215 RRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFID 274
Query: 348 TVSQIISGWVADQNWIKKY--HYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
++ +G+VA ++ Y + + G+ +L A + L+ + I F I G
Sbjct: 275 IFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGM 334
Query: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
AL VL+ + + +GL +AVL GPP G L D T Y F +G
Sbjct: 335 VGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAE 394
Query: 466 YLLSSV 471
L SS+
Sbjct: 395 VLTSSL 400
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 107 bits (266), Expect = 3e-23
Identities = 54/184 (29%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
DG W W++++ + +G IFF Q EF+ ++ + W SI++++ AGP
Sbjct: 9 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68
Query: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
L +I+ G + T +LG + + G + SS++ ++ L T G + GLG F +Q + V
Sbjct: 69 LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128
Query: 136 TTKYFKKRLALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPSSML 194
YF +R L+ A+A G+ L L P +++L++ W G ++FG I L+ +
Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188
Query: 195 LRPI 198
+RP+
Sbjct: 189 IRPV 192
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 291 FDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVS 350
FDI L N + ++ + S L + +P LV A +D A+ L+S+ G
Sbjct: 229 FDI-LRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFL 287
Query: 351 QIISGWVADQNWIKKYHYHKSYL-----ILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
+ ++G +A + + H+ YL +L G+TNL+ + F +L+ Y + +++ G
Sbjct: 288 RPLAGLMAGR---PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSG 344
Query: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
ALI VL+D+ R LGL + G+A L PP+AG L D T ++ FY S
Sbjct: 345 IGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF- 403
Query: 466 YLLSSVSF 473
+L+S+ F
Sbjct: 404 FLISAALF 411
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 92.4 bits (228), Expect = 8e-19
Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 6/161 (3%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSE-----QIGWIGSIMSSLR 70
+GGWGW++++ N V G+ + FV E F + + W+GS+ +
Sbjct: 66 EGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMI 125
Query: 71 FCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQ 130
F P+V++ D+ G + T+++GA V G + SS+ +SI L +T G++ G +F YQ
Sbjct: 126 FFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQ 185
Query: 131 VAAVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLID 170
+ V+ YFKKRL L I +G + T LL + LID
Sbjct: 186 PSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLID 226
Score = 82.8 bits (203), Expect = 6e-16
Identities = 44/191 (23%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Query: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
K++F+ ++F+ + ++ L+ YF+P HL+ D + ++ G+
Sbjct: 280 KKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTS 339
Query: 348 TVSQIISGWVADQ-NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGY 406
V +++ G +AD +KK + G+ +++ PL + F L+ + +F G +
Sbjct: 340 GVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCF 399
Query: 407 LALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICY 466
++++ P+ +L V++ +G F + + GPPIAG L D +Y+ +FY +G+
Sbjct: 400 ISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPP 459
Query: 467 LLSSVSFFFVP 477
L+ F+P
Sbjct: 460 LIGGAVLCFIP 470
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 84.7 bits (208), Expect = 2e-16
Identities = 46/192 (23%), Positives = 98/192 (51%), Gaps = 1/192 (0%)
Query: 288 KQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILE 347
++ F++ +FR + I+ + + L YF+P HL+ + +I + L+ G
Sbjct: 382 RKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATS 441
Query: 348 TVSQIISGWVADQ-NWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGY 406
+ +++SG ++D +KK + +L G+ +++ PL F L+ + + G +
Sbjct: 442 GLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFF 501
Query: 407 LALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICY 466
+ ++ P+ +L ++ +G + +++GPPIAG L + Y+ +FYF+G+
Sbjct: 502 ITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPP 561
Query: 467 LLSSVSFFFVPL 478
++ +V FFVPL
Sbjct: 562 IIGAVILFFVPL 573
Score = 81.3 bits (199), Expect = 2e-15
Identities = 44/153 (28%), Positives = 79/153 (51%), Gaps = 4/153 (2%)
Query: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQI----GWIGSIMSSLRF 71
+GG+GW++V N + G+ + I + + EE + + Q+ W+G++ + F
Sbjct: 170 EGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIF 229
Query: 72 CAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQV 131
P+V+I D LG + T+ GA V G SS+ +S+ T G+L G G +F +Q
Sbjct: 230 FCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQP 289
Query: 132 AAVVTTKYFKKRLALSTAIARSGMGLTFLLAPF 164
+ V+ YF++RL L+ + +G + + PF
Sbjct: 290 SLVILGHYFQRRLGLANGVVSAGSSIFSMSFPF 322
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 291 FDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVS 350
FDI L N + ++ + S L + +P LV A +D A+ L+S+ G
Sbjct: 177 FDI-LRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFL 235
Query: 351 QIISGWVADQNWIKKYHYHKSYL-----ILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
+ ++G +A + + H+ YL +L G+TNL+ + F +L+ Y + +++ G
Sbjct: 236 RPLAGLMAGR---PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSG 292
Query: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
ALI VL+D+ R LGL + G+A L PP+AG L D T ++ FY S
Sbjct: 293 IGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF- 351
Query: 466 YLLSSVSF 473
+L+S+ F
Sbjct: 352 FLISAALF 359
Score = 68.6 bits (166), Expect = 1e-11
Identities = 38/125 (30%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 75 PLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAV 134
PL +I+ G + T +LG + + G + SS++ ++ L T G + GLG F +Q +
Sbjct: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
Query: 135 VTTKYFKKRLALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPSSM 193
V YF +R L+ A+A G+ L L P +++L++ W G ++FG I L+
Sbjct: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
Query: 194 LLRPI 198
++RP+
Sbjct: 136 IIRPV 140
>gi|4503847 solute carrier family 37 (glucose-6-phosphate
transporter), member 4 [Homo sapiens]
Length = 429
Score = 37.0 bits (84), Expect = 0.040
Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
Query: 39 KTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVT 98
KTF+ EE + +G+I S S+ + + ++ D + + G +V
Sbjct: 29 KTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVG 88
Query: 99 GGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFK-KRLALSTAIARSGMGL 157
+ +W++++P + + L GL + V K+F+ + AI + M L
Sbjct: 89 LVNIFFAWSSTVP-VFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNL 147
Query: 158 TFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIH 199
L P L Y W L L GA+ +V S + L IH
Sbjct: 148 AGGLGPILATILAQSYSWRSTLALSGALC--VVVSFLCLLLIH 188
>gi|217416366 major facilitator superfamily domain containing 9
[Homo sapiens]
Length = 474
Score = 36.6 bits (83), Expect = 0.053
Identities = 46/193 (23%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 3 KREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVV----FQEEFEGTSEQ 58
K+E K + D G + FL+ ++++G F + VV + G S
Sbjct: 23 KQEQKTGTEAEAADSG---AVGARRFLLCLYLVGFLDLFGVSMVVPLLSLHVKSLGASPT 79
Query: 59 I-GWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTM 117
+ G +GS L+ + LV D++G +++ + + GYL+ AT++ FL V
Sbjct: 80 VAGIVGSSYGILQLFSSTLVGCWSDVVGRRSSLLACILLSALGYLLLGAATNV-FLFVLA 138
Query: 118 GLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFT-KFLIDLYD--W 174
+ G+ L A+++ +K L + G+ F+L P +L +L D +
Sbjct: 139 RVPAGIFKHTLSISRALLSDVVPEKERPLVIGHFNTASGVGFILGPVVGGYLTELEDGFY 198
Query: 175 TGALILFGAIALN 187
A I F LN
Sbjct: 199 LTAFICFLVFILN 211
Score = 29.3 bits (64), Expect = 8.4
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 6/147 (4%)
Query: 322 LVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNL 381
L K+LG A + S GIL+ S + G +D + + + ++L + L
Sbjct: 67 LSLHVKSLGASPTVAGIVGSSYGILQLFSSTLVGCWSDV--VGRRSSLLACILLSALGYL 124
Query: 382 LAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSG 441
L AT L + + IF L++ +L D+ +G + +G+ + G
Sbjct: 125 LLGAATNVFLFVLARVPAGIFKHT-LSISRALLSDVVPEKERPLVIGHFNTASGVGFILG 183
Query: 442 PPIAGWLYDYTQTYNGSFYFSGICYLL 468
P + G+L T+ +G + + IC+L+
Sbjct: 184 PVVGGYL---TELEDGFYLTAFICFLV 207
>gi|225703102 major facilitator superfamily domain containing 10
[Homo sapiens]
Length = 455
Score = 35.0 bits (79), Expect = 0.15
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 3/105 (2%)
Query: 60 GWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLC-VTMG 118
G IGS S L+F PL D LG + +L V Y + WATS F +
Sbjct: 90 GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAV--WATSRSFAAFLASR 147
Query: 119 LLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAP 163
L+ G+ + A+V + A+ L F L P
Sbjct: 148 LIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGP 192
>gi|225703104 major facilitator superfamily domain containing 10
[Homo sapiens]
Length = 455
Score = 35.0 bits (79), Expect = 0.15
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 3/105 (2%)
Query: 60 GWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLC-VTMG 118
G IGS S L+F PL D LG + +L V Y + WATS F +
Sbjct: 90 GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAV--WATSRSFAAFLASR 147
Query: 119 LLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAP 163
L+ G+ + A+V + A+ L F L P
Sbjct: 148 LIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGP 192
>gi|166064062 tumor suppressing subtransferable candidate 5 [Homo
sapiens]
Length = 424
Score = 33.1 bits (74), Expect = 0.58
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 8/151 (5%)
Query: 303 IFTWSFLLSQLAYFIPTFHLVAR-AKTLGIDIMDASYLVSVAGILETVSQIISGWVADQN 361
+ T+ ++L F +V ++ LG+D + YL + G+L+ + + G ADQ
Sbjct: 27 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQR 86
Query: 362 WIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILP----VLVDL 417
+ S+L + LLA A + P L + FA G L LP V+ DL
Sbjct: 87 GARA-ALTLSFLAALALYLLLA--AASSPALPGVYLLFASRLPGALMHTLPAAQMVITDL 143
Query: 418 CRNSTVNRFLGLASFFAGMAVLSGPPIAGWL 448
LG G+ V+ G + G L
Sbjct: 144 SAPEERPAALGRLGLCFGVGVILGSLLGGTL 174
>gi|166064060 tumor suppressing subtransferable candidate 5 [Homo
sapiens]
Length = 424
Score = 33.1 bits (74), Expect = 0.58
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 8/151 (5%)
Query: 303 IFTWSFLLSQLAYFIPTFHLVAR-AKTLGIDIMDASYLVSVAGILETVSQIISGWVADQN 361
+ T+ ++L F +V ++ LG+D + YL + G+L+ + + G ADQ
Sbjct: 27 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQR 86
Query: 362 WIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILP----VLVDL 417
+ S+L + LLA A + P L + FA G L LP V+ DL
Sbjct: 87 GARA-ALTLSFLAALALYLLLA--AASSPALPGVYLLFASRLPGALMHTLPAAQMVITDL 143
Query: 418 CRNSTVNRFLGLASFFAGMAVLSGPPIAGWL 448
LG G+ V+ G + G L
Sbjct: 144 SAPEERPAALGRLGLCFGVGVILGSLLGGTL 174
>gi|53828692 olfactory receptor, family 4, subfamily K, member 5
[Homo sapiens]
Length = 323
Score = 31.6 bits (70), Expect = 1.7
Identities = 16/51 (31%), Positives = 23/51 (45%)
Query: 273 LKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLV 323
LKS K S + + LF P +I+ W F +S L F+ F+ V
Sbjct: 227 LKSSAAMAKAFSTLASHIAVVILFFGPCIFIYVWPFTISPLDKFLAIFYTV 277
>gi|53933201 olfactory receptor, family 5, subfamily B, member 2
[Homo sapiens]
Length = 309
Score = 31.2 bits (69), Expect = 2.2
Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 14/111 (12%)
Query: 374 ILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASF- 432
IL G+T++ PL + +T + + G L ++L +L+D C ++ + FL S
Sbjct: 11 ILLGLTSVPE---LQIPLFILFTFIYLLTLCGNLGMMLLILMDSCLHTPMYFFLSNLSLV 67
Query: 433 -FAGMAVLSGPPIAGWLY-DYTQTYNG----SFYFSGIC----YLLSSVSF 473
F + ++ +AG+L D +YN F+F + YLL+S+++
Sbjct: 68 DFGYSSAVTPKVMAGFLRGDKVISYNACAVQMFFFVALATVENYLLASMAY 118
>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
1 [Homo sapiens]
Length = 891
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 12/60 (20%)
Query: 230 HETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQ 289
H T T +STTQ + P T++ S E Y+GP E+D+V+S+ CK+
Sbjct: 681 HLTSVETTPESTTQLSISPKSPPTLAVTASSE-YSGP-----------ETDRVVSFKCKK 728
>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
2 [Homo sapiens]
Length = 584
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 12/60 (20%)
Query: 230 HETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQ 289
H T T +STTQ + P T++ S E Y+GP E+D+V+S+ CK+
Sbjct: 374 HLTSVETTPESTTQLSISPKSPPTLAVTASSE-YSGP-----------ETDRVVSFKCKK 421
>gi|50080195 olfactory receptor, family 5, subfamily A, member 2
[Homo sapiens]
Length = 324
Score = 30.8 bits (68), Expect = 2.9
Identities = 31/160 (19%), Positives = 57/160 (35%), Gaps = 28/160 (17%)
Query: 289 QLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILET 348
++F LF + W+ L L H+ + +D Y+ S T
Sbjct: 25 KIFLFMLFLGLYLLTLAWNLSLIALIKMDSHLHMPMYFFLSNLSFLDICYVSS------T 78
Query: 349 VSQIISGWVADQNWIKKYHYHKSYLILCGI----TNLLAPLA----------TTFPLLMT 394
+++S + +Q I Y + CG+ LLA +A + +L++
Sbjct: 79 APKMLSDIITEQKTISFVGCATQYFVFCGMGLTECFLLAAMAYDRYAAICNPLLYTVLIS 138
Query: 395 YTICFAIFAGGYLALILPVLV--------DLCRNSTVNRF 426
+T+C + G Y+ L + D C +N F
Sbjct: 139 HTLCLKMVVGAYVGGFLSSFIETYSVYQHDFCGPYMINHF 178
>gi|31542731 major facilitator superfamily domain containing 7 [Homo
sapiens]
Length = 559
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 21 WMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAII 80
W+ ++ L+N + +FA V E+ + EQI W+ + + G I
Sbjct: 30 WVFLLAISLLNCSNATLWLSFAPVADVIAEDLVLSMEQINWLSLVYLVVSTPFGVAAIWI 89
Query: 81 CDILGEKTTSILGAFVVTGGYLI 103
D +G + +ILGA++ G ++
Sbjct: 90 LDSVGLRAATILGAWLNFAGSVL 112
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 30.4 bits (67), Expect = 3.8
Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 16/101 (15%)
Query: 80 ICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKY 139
+C I+G S G FV G LI S + + + +G L + A Y
Sbjct: 43 VCLIVGNMIGS--GIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA--------- 91
Query: 140 FKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALIL 180
L T I +SG ++L F FL + WT LI+
Sbjct: 92 -----ELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,076,300
Number of Sequences: 37866
Number of extensions: 697978
Number of successful extensions: 2305
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2219
Number of HSP's gapped (non-prelim): 80
length of query: 487
length of database: 18,247,518
effective HSP length: 106
effective length of query: 381
effective length of database: 14,233,722
effective search space: 5423048082
effective search space used: 5423048082
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.