Search of human proteins with 4758416

Search of human proteins with 4758416

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758416 golgi-specific brefeldin A resistant guanine
nucleotide exchange factor 1 [Homo sapiens]
         (1859 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...  3717   0.0  
gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange...   258   5e-68
gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange pr...   232   3e-60
gi|4758968 cytohesin 3 [Homo sapiens]                                 152   3e-36
gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]                     149   2e-35
gi|4758964 cytohesin 1 isoform 1 [Homo sapiens]                       149   2e-35
gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]                     144   8e-34
gi|8670546 cytohesin 2 isoform 1 [Homo sapiens]                       144   8e-34
gi|7019505 cytohesin 4 [Homo sapiens]                                 140   2e-32
gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]      137   1e-31
gi|50582989 IQ motif and Sec7 domain 1 isoform b [Homo sapiens]       137   1e-31
gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens]                 136   2e-31
gi|53832026 IQ motif and Sec7 domain 2 isoform 2 [Homo sapiens]       132   2e-30
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]       132   2e-30
gi|45827716 ADP-ribosylation factor guanine nucleotide factor 6 ...   103   2e-21
gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6...   103   2e-21
gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]      101   8e-21
gi|14150035 pleckstrin and Sec7 domain containing 2 [Homo sapiens]     99   5e-20
gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens]     87   1e-16
gi|48928044 F-box only protein 8 [Homo sapiens]                        56   3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    56   4e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    51   9e-06
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    51   9e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    51   9e-06
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    51   9e-06
gi|51173735 ras responsive element binding protein 1 isoform 2 [...    51   1e-05
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    51   1e-05
gi|153792074 proline rich 12 [Homo sapiens]                            50   2e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    49   6e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             47   2e-04

>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
            exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 3717 bits (9639), Expect = 0.0
 Identities = 1859/1859 (100%), Positives = 1859/1859 (100%)

Query: 1    MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 60
            MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE
Sbjct: 1    MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE 60

Query: 61   PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 120
            PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR
Sbjct: 61   PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR 120

Query: 121  FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 180
            FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS
Sbjct: 121  FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS 180

Query: 181  AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 240
            AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM
Sbjct: 181  AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM 240

Query: 241  TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 300
            TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT
Sbjct: 241  TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT 300

Query: 301  TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC 360
            TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC
Sbjct: 301  TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEEC 360

Query: 361  TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR 420
            TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR
Sbjct: 361  TSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDR 420

Query: 421  HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC 480
            HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC
Sbjct: 421  HNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRVC 480

Query: 481  FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI 540
            FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI
Sbjct: 481  FLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYI 540

Query: 541  NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL 600
            NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL
Sbjct: 541  NYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNSL 600

Query: 601  TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG 660
            TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG
Sbjct: 601  TQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSG 660

Query: 661  CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF 720
            CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF
Sbjct: 661  CSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQF 720

Query: 721  LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE 780
            LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE
Sbjct: 721  LQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDE 780

Query: 781  ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH 840
            ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH
Sbjct: 781  ALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNH 840

Query: 841  NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW 900
            NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW
Sbjct: 841  NVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVW 900

Query: 901  NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK 960
            NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK
Sbjct: 901  NVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRK 960

Query: 961  CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG 1020
            CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG
Sbjct: 961  CAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHG 1020

Query: 1021 DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV 1080
            DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV
Sbjct: 1021 DILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFV 1080

Query: 1081 SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS 1140
            SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS
Sbjct: 1081 SWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVS 1140

Query: 1141 VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV 1200
            VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV
Sbjct: 1141 VTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAV 1200

Query: 1201 VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG 1260
            VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG
Sbjct: 1201 VGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSG 1260

Query: 1261 DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS 1320
            DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS
Sbjct: 1261 DDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDS 1320

Query: 1321 EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD 1380
            EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD
Sbjct: 1321 EVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGLD 1380

Query: 1381 LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH 1440
            LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH
Sbjct: 1381 LGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSH 1440

Query: 1441 KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD 1500
            KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD
Sbjct: 1441 KYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLLD 1500

Query: 1501 LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV 1560
            LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV
Sbjct: 1501 LMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQV 1560

Query: 1561 RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS 1620
            RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS
Sbjct: 1561 RMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRAS 1620

Query: 1621 TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT 1680
            TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT
Sbjct: 1621 TLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDT 1680

Query: 1681 AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH 1740
            AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH
Sbjct: 1681 AEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASAH 1740

Query: 1741 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP 1800
            LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP
Sbjct: 1741 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGP 1800

Query: 1801 PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1859
            PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN
Sbjct: 1801 PPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN 1859


>gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange
            factor 2 [Homo sapiens]
          Length = 1785

 Score =  258 bits (658), Expect = 5e-68
 Identities = 300/1265 (23%), Positives = 546/1265 (43%), Gaps = 153/1265 (12%)

Query: 59   IEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTH 118
            IE + +  PF    +S+     +   +L  + K ++Y  I      +    + + D +  
Sbjct: 63   IEADKYFLPFELACQSKSPR--VVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVE 120

Query: 119  ---ARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSE 175
               + F G  P +DE V ++I++ L T + +P    +   ++ + +++C+ I    + + 
Sbjct: 121  TICSCFQG--PQTDEGVQLQIIKALLTAVTSP-HIEIHEGTILQTVRTCYNIYLASK-NL 176

Query: 176  LLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPR 235
            + + +A+ TL  M+ ++FTR+       +N V    ++L+        S   +    SP+
Sbjct: 177  INQTTAKATLTQMLNVIFTRM-------ENQVLQEARELEKPIQSKPQSPVIQAAAVSPK 229

Query: 236  PPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLE 295
              R +      S+  TP  T L++          V T    A  E  S++      SG +
Sbjct: 230  FVR-LKHSQAQSKPTTPEKTDLTNGEHARSDSGKVSTENGDAPRERGSSL------SGTD 282

Query: 296  FSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPE 355
              +Q   K+ L D+        ++A +  + + G+ E P+   G  +E  + A    + E
Sbjct: 283  DGAQEVVKDILEDV-------VTSAIKEAAEKHGLTE-PERVLG-ELECQECAIPPGVDE 333

Query: 356  VLEECTSPADHSDSASVHDMDYVNPRG----VRFTQSSQKEGTALVPYGLPCIRELFRFL 411
               +    AD   S S  D    + +G     RF+   QK+   +           FR L
Sbjct: 334  N-SQTNGIADDRQSLSSADNLESDAQGHQVAARFSHVLQKDAFLV-----------FRSL 381

Query: 412  ISLT------NPHDRHNSEVMIHM-GLHLLTVALESA-PVAQCQTL-LGLIKDEMCRHLF 462
              L+       P D  + E+   +  L LL   L++A PV +   + +  IK  +C  L 
Sbjct: 382  CKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRTHEMFINAIKQYLCVALS 441

Query: 463  QLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMAL 522
            +       +++  SL +   L  + + HLK Q+E++ K++   I +E     +E + M +
Sbjct: 442  KNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNI-LETSTSSFEHRWMVI 500

Query: 523  EAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALL 582
            + + ++      V ++Y+NYDCD   +N+FE L   LSK A   SG     H L +  L 
Sbjct: 501  QTLTRICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSG-----HELGMTPLQ 555

Query: 583  TV-IDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDI 641
             + +      C   +L  + +  K     P+ +   G      T++   DGK + MA   
Sbjct: 556  ELSLRKKGLECLVSILKCMVEWSKDLYVNPNHQTSLGQERL--TDQEIGDGKGLDMAR-- 611

Query: 642  PGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKK 701
                            +   + +E  V SG            + +  DP +   IK +K+
Sbjct: 612  ----------------RCSVTSMESTVSSGTQ----------TTVQDDPEQFEVIKQQKE 645

Query: 702  LLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSD--RK 759
            ++  G E FN+KPK+GIQFLQE+G+L   ++  ++AQ+L +  RLD   +G+F+ D  R 
Sbjct: 646  IIEHGIELFNKKPKRGIQFLQEQGMLGTSVE--DIAQFLHQEERLDSTQVGDFLGDSARF 703

Query: 760  NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSP--F 817
            N +++ ++V    F       ALR +LE FRLPGEA  I RL+E F  R++ CN     F
Sbjct: 704  NKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTLF 763

Query: 818  ANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYH 877
            A++D  + LAY++IML TD H+  V+ +   MT E++ K  +G+N  KD  ++ L  +Y 
Sbjct: 764  ASADTAYVLAYSIIMLTTDLHSPQVKNK---MTKEQYIKMNRGINDSKDLPEEYLSSIYE 820

Query: 878  AIKNEEIVMPEEQ-----TGLVREN--------YVWNVLLHRGA-TPEGIFLRVP----- 918
             I+ ++I M E +     T   ++N         ++N+ + + A T + +   V      
Sbjct: 821  EIEGKKIAMKETKELTIATKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHAKAP 880

Query: 919  -TASYDLD----LFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDV 973
             T++  LD    +F + W P +AA S       +  +    + G R    I+  +G+   
Sbjct: 881  FTSATHLDHVRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLE 940

Query: 974  FDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEA 1033
             D  + +L +F+ L++ S     S+     K     KT+  +AH  G+ L   W  I++ 
Sbjct: 941  RDAYVQALARFSLLTASS-----SITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKC 995

Query: 1034 MLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSV 1093
            + QL  AQL+   +     ++  +G     RE   S +G +        L L       V
Sbjct: 996  ISQLELAQLIGTGV--KTRYLSGSG-----REREGSLKGHTLAGEEFMGLGLGNLVSGGV 1048

Query: 1094 -RGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEED 1152
             +      QE+             +++ T S  L   ++ + ++ L +V+ DE       
Sbjct: 1049 DKRQMASFQESVGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELASPHHP 1108

Query: 1153 AAFCLEMLLRIVLENRDRV----GCVWQTVRDHLYHL-CVQAQDFCFLVERAVVGLLRLA 1207
              F L+ ++ I   N +R+      +W  + DH   + C   +D       AV  L +L+
Sbjct: 1109 RMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVGCNPNEDVAIF---AVDSLRQLS 1165

Query: 1208 IRLLRREEIS---AQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWA 1264
            ++ L + E++    Q         +MK +    +       + +++ + AANI SG  W 
Sbjct: 1166 MKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMAIRCIAQMVNSQAANIRSG--WK 1223

Query: 1265 TLFTL 1269
             +F +
Sbjct: 1224 NIFAV 1228


>gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange protein
            1 [Homo sapiens]
          Length = 1849

 Score =  232 bits (591), Expect = 3e-60
 Identities = 294/1296 (22%), Positives = 545/1296 (42%), Gaps = 162/1296 (12%)

Query: 59   IEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYA-LIDPTHEGTAEGMENMADAVT 117
            IE + +  PF    +S+     I   +L  + K ++Y  L     + T  G + +   + 
Sbjct: 75   IEADKYFLPFELACQSKCPR--IVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIE 132

Query: 118  HARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELL 177
                    P +DE V ++I++ L T + T     +   +V + +++C+ I    + + + 
Sbjct: 133  TICGCFQGPQTDEGVQLQIIKALLTAV-TSQHIEIHEGTVLQAVRTCYNIYLASK-NLIN 190

Query: 178  RKSAEHTLVDMVQLLFTRLP-QFKEEPKNYVGTNMKKLKMRAGG-MSDSSKWKKQKRSPR 235
            + +A+ TL  M+ ++F R+  Q  +E K      M+K + R    +  S     +  SP+
Sbjct: 191  QTTAKATLTQMLNVIFARMENQALQEAKQ-----MEKERHRQHHHLLQSPVSHHEPESPQ 245

Query: 236  ----PPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEA-----ASAVV 286
                PP+ +  ++   E      T             +  + ISSA +E      A+A  
Sbjct: 246  LRYLPPQTVDHISQEHEGDLDLHTNDVDKSLQDDTEPENGSDISSAENEQTEADQATAAE 305

Query: 287  SPSTDSGLEFSSQTTSKEDLTDLEQP----------GSPGYSTATEPGSS-ELGVPEQPD 335
            + S +  L        +E   D+ Q           G  G  T     +   +G      
Sbjct: 306  TLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT----- 360

Query: 336  LQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPR-----GVRFTQSSQ 390
            +++G+  E  Q+  +   P  +    S  D   S S +D            G +F+   Q
Sbjct: 361  IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQ 420

Query: 391  KEGTALVPYGLPCIRELFRFLISLT------NPHDRHNSEVMIH-MGLHLLTVALESA-P 442
            K+   +           FR L  L+       P D  + E+    + L LL   L++A P
Sbjct: 421  KDAFLV-----------FRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGP 469

Query: 443  VAQCQTL-LGLIKDEMCRHLFQLLSIERLNLYAASLRVCFLLFESMREHLKFQMEMYIKK 501
            + +   + +  IK  +C  L +        ++  SL +   L  + + HLK Q+E++ K+
Sbjct: 470  IFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKE 529

Query: 502  LMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSK 561
            +   I +E     ++ K M ++ + ++      V ++Y+NYDCD   +N+FE L   LSK
Sbjct: 530  IFLYI-LETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSK 588

Query: 562  NAFPVSGQ-LYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTR 620
             A     Q L  +++  L      +      C   +L  + +  K +   P+ +   G  
Sbjct: 589  IAQGRGSQELGMSNVQELS-----LRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQE 643

Query: 621  EASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFARKP 680
            + S  E            S+I         + P    + G  +  E+  S     ++ + 
Sbjct: 644  KPSEQE-----------MSEI---------KHPETINRYGSLNSLESTSSSGIGSYSTQM 683

Query: 681  PRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLL-TIPMDNTEVAQW 739
                    +P +   +K +K+++  G + FN+KPK+GIQ+LQE+G+L T P D   +AQ+
Sbjct: 684  SG----TDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLGTTPED---IAQF 736

Query: 740  LRENPRLDKKMIGEFV--SDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPV 797
            L +  RLD   +GEF+  +D+ N +++ ++V    F G     ALR++LE FRLPGEA  
Sbjct: 737  LHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQK 796

Query: 798  IQRLLEAFTERWMNCNGSP--FANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFR 855
            I RL+E F  R++ CN     FA++D  + LAY++IML TD H+  V+ +   MT E++ 
Sbjct: 797  IDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNK---MTKEQYI 853

Query: 856  KNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLV-------------RENYVWNV 902
            K  +G+N  KD  ++ L  +Y+ I  ++I M E +   +             +   ++N+
Sbjct: 854  KMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQNVASEKQRRLLYNL 913

Query: 903  LLHRGA-TPEGIFLRVP------TASYDLD----LFTMTWGPTIAALSYVFDKSLEETII 951
             + + A T + +   V       T++  L+    +F + W P +AA S       +  + 
Sbjct: 914  EMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVA 973

Query: 952  QKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKT 1011
               + G R    I+  + +    D  + +L +FT L+  S      +     K     KT
Sbjct: 974  SLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSS-----GITEMKQKNIDTIKT 1028

Query: 1012 VFHLAHRHGDILREGWKNIMEAMLQLFRAQLL---PKAMIEVEDFVDPNGKISLQREETP 1068
            +  +AH  G+ L   W  I++ + QL  AQL+    K            G ++  +++ P
Sbjct: 1029 LITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAP 1088

Query: 1069 SN-RGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQ 1127
                G   V   V W  ++  ++S   G ++       V          +++ T S  L 
Sbjct: 1089 DEFVGLGLVGGNVDWKQIASIQESI--GETSSQSVVVAV----------DRIFTGSTRLD 1136

Query: 1128 LESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRV----GCVWQTVRDHLY 1183
              ++ + ++ L +V+ DE         F L+ ++ I   N  R+      +W+ + DH  
Sbjct: 1137 GNAIVDFVRWLCAVSMDELLSTTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFN 1196

Query: 1184 HL-CVQAQDFCFLVERAVVGLLRLAIRLLRREEIS---AQVLLSLRILLLMKPSVLSRVS 1239
             + C   +D       AV  L +L+++ L + E++    Q         +MK +    + 
Sbjct: 1197 KVGCNPNEDVAIF---AVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIR 1253

Query: 1240 HQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGS 1275
              V   + +++ + AANI SG  W  +F++     S
Sbjct: 1254 DMVVRCIAQMVNSQAANIRSG--WKNIFSVFHLAAS 1287



 Score = 31.2 bits (69), Expect = 9.8
 Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 40/213 (18%)

Query: 1537 LWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPL 1596
            +W   W P+L  ++C+    +  VR + LT      ++ ++ K     +E  + + LF +
Sbjct: 1377 VWVRGWFPILFELSCIINRCKLDVRTRGLT------VMFEIMKTYGHTYEKHWWQDLFRI 1430

Query: 1597 LTKLLENISPAD-----VGGMEETRMRASTLLSKVFLQH---LSPLLSLSTFAALWLTIL 1648
            + ++ +N+   +        M  T   A   +  VF Q+   LS +L    FA L+  + 
Sbjct: 1431 VFRIFDNMKLPEQQTEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQ 1490

Query: 1649 DFMDKYMHAGSSDLLSEAIPESLKNMLLVMD-----TAEIFHSADARGGGPSALWEITWE 1703
               ++   +G++ L +  I    K  L + D     T +IF +       P AL  +TW 
Sbjct: 1491 QDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTI-----PHAL--LTWR 1543

Query: 1704 RIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPL 1736
                  P+  +          P P  P  +KPL
Sbjct: 1544 ------PNSGETA--------PPPPSPVSEKPL 1562


>gi|4758968 cytohesin 3 [Homo sapiens]
          Length = 399

 Score =  152 bits (384), Expect = 3e-36
 Identities = 82/193 (42%), Positives = 122/193 (63%), Gaps = 7/193 (3%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDR 758
           + K +  G ++FN  PKKGIQFL E  LL    +  +VAQ+L +   L+K +IG+++ +R
Sbjct: 66  RNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPE--DVAQFLYKGEGLNKTVIGDYLGER 123

Query: 759 K--NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSP 816
              NI +L++FV    F  L L +ALR +L +FRLPGEA  I R++EAF  R+  CN   
Sbjct: 124 DEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGV 183

Query: 817 FANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMY 876
           F ++D C+ L++A+IMLNT  HNHNVR +    T E F    +G+N G D  +++L ++Y
Sbjct: 184 FQSTDTCYVLSFAIIMLNTSLHNHNVRDK---PTAERFIAMNRGINEGGDLPEELLRNLY 240

Query: 877 HAIKNEEIVMPEE 889
            +IKNE   +PE+
Sbjct: 241 ESIKNEPFKIPED 253


>gi|110349763 cytohesin 1 isoform 2 [Homo sapiens]
          Length = 397

 Score =  149 bits (376), Expect = 2e-35
 Identities = 79/193 (40%), Positives = 121/193 (62%), Gaps = 7/193 (3%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDR 758
           + K +  G ++FN  PKKGIQFL E  LL    +  ++AQ+L +   L+K  IG+++ +R
Sbjct: 62  RNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCE--DIAQFLYKGEGLNKTAIGDYLGER 119

Query: 759 K--NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSP 816
              NI +L +FV    F  L L +ALR +L +FRLPGEA  I R++EAF +R+  CN   
Sbjct: 120 DEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGV 179

Query: 817 FANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMY 876
           F ++D C+ L++A+IMLNT  HN NV+ +    T+E F    +G+N G D  +++L ++Y
Sbjct: 180 FQSTDTCYVLSFAIIMLNTSLHNPNVKDK---PTVERFIAMNRGINDGGDLPEELLRNLY 236

Query: 877 HAIKNEEIVMPEE 889
            +IKNE   +PE+
Sbjct: 237 ESIKNEPFKIPED 249


>gi|4758964 cytohesin 1 isoform 1 [Homo sapiens]
          Length = 398

 Score =  149 bits (376), Expect = 2e-35
 Identities = 79/193 (40%), Positives = 121/193 (62%), Gaps = 7/193 (3%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDR 758
           + K +  G ++FN  PKKGIQFL E  LL    +  ++AQ+L +   L+K  IG+++ +R
Sbjct: 62  RNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCE--DIAQFLYKGEGLNKTAIGDYLGER 119

Query: 759 K--NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSP 816
              NI +L +FV    F  L L +ALR +L +FRLPGEA  I R++EAF +R+  CN   
Sbjct: 120 DEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGV 179

Query: 817 FANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMY 876
           F ++D C+ L++A+IMLNT  HN NV+ +    T+E F    +G+N G D  +++L ++Y
Sbjct: 180 FQSTDTCYVLSFAIIMLNTSLHNPNVKDK---PTVERFIAMNRGINDGGDLPEELLRNLY 236

Query: 877 HAIKNEEIVMPEE 889
            +IKNE   +PE+
Sbjct: 237 ESIKNEPFKIPED 249


>gi|195972859 cytohesin 2 isoform 2 [Homo sapiens]
          Length = 399

 Score =  144 bits (363), Expect = 8e-34
 Identities = 80/195 (41%), Positives = 122/195 (62%), Gaps = 11/195 (5%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNT--EVAQWLRENPRLDKKMIGEFVS 756
           + + +  G ++FN  PKKGIQFL E  LL     NT  E+A++L +   L+K  IG+++ 
Sbjct: 61  RNRKMAMGRKKFNMDPKKGIQFLVENELL----QNTPEEIARFLYKGEGLNKTAIGDYLG 116

Query: 757 DRKNIDL--LESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNG 814
           +R+ ++L  L +FV    F  L L +ALR +L +FRLPGEA  I R++EAF +R+  CN 
Sbjct: 117 EREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNP 176

Query: 815 SPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILED 874
             F ++D C+ L++AVIMLNT  HN NVR +     LE F    +G+N G D  +++L +
Sbjct: 177 GVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG---LERFVAMNRGINEGGDLPEELLRN 233

Query: 875 MYHAIKNEEIVMPEE 889
           +Y +I+NE   +PE+
Sbjct: 234 LYDSIRNEPFKIPED 248


>gi|8670546 cytohesin 2 isoform 1 [Homo sapiens]
          Length = 400

 Score =  144 bits (363), Expect = 8e-34
 Identities = 80/195 (41%), Positives = 122/195 (62%), Gaps = 11/195 (5%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNT--EVAQWLRENPRLDKKMIGEFVS 756
           + + +  G ++FN  PKKGIQFL E  LL     NT  E+A++L +   L+K  IG+++ 
Sbjct: 61  RNRKMAMGRKKFNMDPKKGIQFLVENELL----QNTPEEIARFLYKGEGLNKTAIGDYLG 116

Query: 757 DRKNIDL--LESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNG 814
           +R+ ++L  L +FV    F  L L +ALR +L +FRLPGEA  I R++EAF +R+  CN 
Sbjct: 117 EREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNP 176

Query: 815 SPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILED 874
             F ++D C+ L++AVIMLNT  HN NVR +     LE F    +G+N G D  +++L +
Sbjct: 177 GVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG---LERFVAMNRGINEGGDLPEELLRN 233

Query: 875 MYHAIKNEEIVMPEE 889
           +Y +I+NE   +PE+
Sbjct: 234 LYDSIRNEPFKIPED 248


>gi|7019505 cytohesin 4 [Homo sapiens]
          Length = 394

 Score =  140 bits (352), Expect = 2e-32
 Identities = 86/236 (36%), Positives = 133/236 (56%), Gaps = 14/236 (5%)

Query: 656 HGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPK 715
           H K    D+++  D  AD  FA+      C   +  E   +  K+K L  G ++FN  P 
Sbjct: 25  HRKQLLEDIQKLKDEIADV-FAQ----IDCF--ESAEESRMAQKEKELCIGRKKFNMDPA 77

Query: 716 KGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRK--NIDLLESFVSTFSF 773
           KGIQ+  E  LLT   D  ++A++L +   L+K  IG ++ +R   N+ +L++FV    F
Sbjct: 78  KGIQYFIEHKLLT--PDVQDIARFLYKGEGLNKTAIGTYLGERDPINLQVLQAFVDCHEF 135

Query: 774 QGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIML 833
             L L +ALR +L +FRLPGEA  I R++EAF  R+  CN   F ++D C+ L++++IML
Sbjct: 136 ANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFATRYCLCNPGVFQSTDTCYVLSFSIIML 195

Query: 834 NTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEE 889
           NT  HN NVR +      E F    +G+N G D  +D L +++ +IK+E   +PE+
Sbjct: 196 NTSLHNPNVRDR---PPFERFVSMNRGINNGSDLPEDQLRNLFDSIKSEPFSIPED 248


>gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]
          Length = 1114

 Score =  137 bits (344), Expect = 1e-31
 Identities = 78/204 (38%), Positives = 122/204 (59%), Gaps = 9/204 (4%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDR 758
           +K+    G   FN+KP+KG+Q+L E+G   +P     VA +L +   L ++MIGEF+ +R
Sbjct: 510 RKRHYRIGLNLFNKKPEKGVQYLIERGF--VPDTPVGVAHFLLQRKGLSRQMIGEFLGNR 567

Query: 759 K---NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGS 815
           +   N D+L+  V    F  + LDEALR +    R+ GEA  ++RL+EAF++R+  CN  
Sbjct: 568 QKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPG 627

Query: 816 ---PFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDIL 872
               F N D  F LA+A+I+LNTD ++ NV K    M LE+F KNL+GV+ G+D  +++L
Sbjct: 628 VVRQFRNPDTIFILAFAIILLNTDMYSPNV-KPERKMKLEDFIKNLRGVDDGEDIPREML 686

Query: 873 EDMYHAIKNEEIVMPEEQTGLVRE 896
             +Y  I+  E+   E+    V++
Sbjct: 687 MGIYERIRKRELKTNEDHVSQVQK 710


>gi|50582989 IQ motif and Sec7 domain 1 isoform b [Homo sapiens]
          Length = 963

 Score =  137 bits (344), Expect = 1e-31
 Identities = 78/204 (38%), Positives = 122/204 (59%), Gaps = 9/204 (4%)

Query: 699 KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDR 758
           +K+    G   FN+KP+KG+Q+L E+G   +P     VA +L +   L ++MIGEF+ +R
Sbjct: 524 RKRHYRIGLNLFNKKPEKGVQYLIERGF--VPDTPVGVAHFLLQRKGLSRQMIGEFLGNR 581

Query: 759 K---NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGS 815
           +   N D+L+  V    F  + LDEALR +    R+ GEA  ++RL+EAF++R+  CN  
Sbjct: 582 QKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPG 641

Query: 816 ---PFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDIL 872
               F N D  F LA+A+I+LNTD ++ NV K    M LE+F KNL+GV+ G+D  +++L
Sbjct: 642 VVRQFRNPDTIFILAFAIILLNTDMYSPNV-KPERKMKLEDFIKNLRGVDDGEDIPREML 700

Query: 873 EDMYHAIKNEEIVMPEEQTGLVRE 896
             +Y  I+  E+   E+    V++
Sbjct: 701 MGIYERIRKRELKTNEDHVSQVQK 724


>gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens]
          Length = 759

 Score =  136 bits (343), Expect = 2e-31
 Identities = 94/285 (32%), Positives = 144/285 (50%), Gaps = 15/285 (5%)

Query: 619 TREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKSGCSDLEEAVDSGADKKFAR 678
           T E    E TA  G+  G  ++   L          +  KSG S+   +    A +    
Sbjct: 268 TEEEEEEEETAEVGR--GAEAEAGDLEQLSSSSTSTKSAKSG-SEASASASKDALQAMIL 324

Query: 679 KPPRFSCLLPDPRELIEIKN---KKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTE 735
             PR+ C  P   +   +     +K+L   G   FN  P KGIQFL  +G   IP     
Sbjct: 325 SLPRYHCENPASCKSPTLSTDTLRKRLYRIGLNLFNINPDKGIQFLISRGF--IPDTPIG 382

Query: 736 VAQWLRENPRLDKKMIGEFVSDRK---NIDLLESFVSTFSFQGLRLDEALRLYLEAFRLP 792
           VA +L +   L ++MIGEF+ + K   N D+L+  V    F  + LDEALR +    R+ 
Sbjct: 383 VAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCVVDEMDFSSMELDEALRKFQAHIRVQ 442

Query: 793 GEAPVIQRLLEAFTERWMNCNG---SPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPM 849
           GEA  ++RL+EAF++R+  CN      F N D  F LA+A+I+LNTD ++ N+ K +  M
Sbjct: 443 GEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIFILAFAIILLNTDMYSPNI-KPDRKM 501

Query: 850 TLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLV 894
            LE+F +NL+GV+ G D  ++++  +Y  I+ +E+   E+    V
Sbjct: 502 MLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELKSNEDHVTYV 546


>gi|53832026 IQ motif and Sec7 domain 2 isoform 2 [Homo sapiens]
          Length = 949

 Score =  132 bits (333), Expect = 2e-30
 Identities = 85/246 (34%), Positives = 138/246 (56%), Gaps = 14/246 (5%)

Query: 657 GKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKK 716
           G S    L E   +G  K+  ++  R S   P     +  +   ++   G   FN+KP+K
Sbjct: 509 GSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRI---GLNLFNKKPEK 565

Query: 717 GIQFLQEKGLLT-IPMDNTEVAQWLRENPRLDKKMIGEFVSDRK---NIDLLESFVSTFS 772
           GIQ+L E+G L+  P+    VA ++ E   L ++MIGEF+ +R+   N D+L+  V    
Sbjct: 566 GIQYLIERGFLSDTPVG---VAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMD 622

Query: 773 FQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGS---PFANSDACFSLAYA 829
           F  + LD+ALR +    R+ GEA  ++RL+EAF++R+  CN +    F N D  F LA+A
Sbjct: 623 FSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFA 682

Query: 830 VIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEE 889
           +I+LNTD ++ +V K    M L++F KNL+GV+ G+D  +D+L  +Y  I+  E+   ++
Sbjct: 683 IILLNTDMYSPSV-KAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDD 741

Query: 890 QTGLVR 895
               V+
Sbjct: 742 HVSQVQ 747


>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
          Length = 1488

 Score =  132 bits (333), Expect = 2e-30
 Identities = 85/246 (34%), Positives = 138/246 (56%), Gaps = 14/246 (5%)

Query: 657 GKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKK 716
           G S    L E   +G  K+  ++  R S   P     +  +   ++   G   FN+KP+K
Sbjct: 714 GSSSRDSLREPPATGLCKQTYQRETRHSWDSPAFNNDVVQRRHYRI---GLNLFNKKPEK 770

Query: 717 GIQFLQEKGLLT-IPMDNTEVAQWLRENPRLDKKMIGEFVSDRK---NIDLLESFVSTFS 772
           GIQ+L E+G L+  P+    VA ++ E   L ++MIGEF+ +R+   N D+L+  V    
Sbjct: 771 GIQYLIERGFLSDTPVG---VAHFILERKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMD 827

Query: 773 FQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGS---PFANSDACFSLAYA 829
           F  + LD+ALR +    R+ GEA  ++RL+EAF++R+  CN +    F N D  F LA+A
Sbjct: 828 FSSMDLDDALRKFQSHIRVQGEAQKVERLIEAFSQRYCVCNPALVRQFRNPDTIFILAFA 887

Query: 830 VIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEE 889
           +I+LNTD ++ +V K    M L++F KNL+GV+ G+D  +D+L  +Y  I+  E+   ++
Sbjct: 888 IILLNTDMYSPSV-KAERKMKLDDFIKNLRGVDNGEDIPRDLLVGIYQRIQGRELRTNDD 946

Query: 890 QTGLVR 895
               V+
Sbjct: 947 HVSQVQ 952



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 39/140 (27%), Positives = 49/140 (35%), Gaps = 36/140 (25%)

Query: 1708 FLPHLRDELFKQTV---IQDPMPMEP----QGQKPLASAH---LTSAAGDTRTPGHPPP- 1756
            F PH R  L + T    +  P P  P    QG K    +H   +  AAG    PG  PP 
Sbjct: 1353 FAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPG 1412

Query: 1757 -----PEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSP-------TPDGP---- 1800
                 P  P        + P SP +     P  P    PS  +P       +P GP    
Sbjct: 1413 GSYSHPHHP--------QSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHAS 1464

Query: 1801 -PPLAQPPLILQPLASPLQV 1819
             PP    P    P A P ++
Sbjct: 1465 GPPGTANPPSANPKAKPSRI 1484



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 28/91 (30%), Positives = 31/91 (34%), Gaps = 31/91 (34%)

Query: 1730 PQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASS 1789
            P GQ  L + H     G    PG  PPP +P          P+ P               
Sbjct: 1258 PDGQSKLQALHAQYCQG----PGPAPPPYLP----------PQQPS-------------- 1289

Query: 1790 PSRLSPTPDGPPPLAQPPLILQPLASPLQVG 1820
               L P P  PPPL Q   I  P AS   VG
Sbjct: 1290 ---LPPPPQQPPPLPQLGSIPPPPASAPPVG 1317


>gi|45827716 ADP-ribosylation factor guanine nucleotide factor 6
           isoform b [Homo sapiens]
          Length = 513

 Score =  103 bits (256), Expect = 2e-21
 Identities = 50/120 (41%), Positives = 77/120 (64%), Gaps = 3/120 (2%)

Query: 765 ESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACF 824
           E ++  F F G+ LD++LR + +AF L GE    +R+L  F+ R+  CN    A+ D   
Sbjct: 85  EEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVH 144

Query: 825 SLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEI 884
            L  A+++LNTD H HN+ K+   MT +EF  NL+GVN G DF +D+L+ +Y++IKNE++
Sbjct: 145 CLTCAIMLLNTDLHGHNIGKK---MTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKL 201


>gi|117606360 ADP-ribosylation factor guanine nucleotide factor 6
           isoform a [Homo sapiens]
          Length = 1047

 Score =  103 bits (256), Expect = 2e-21
 Identities = 50/120 (41%), Positives = 77/120 (64%), Gaps = 3/120 (2%)

Query: 765 ESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACF 824
           E ++  F F G+ LD++LR + +AF L GE    +R+L  F+ R+  CN    A+ D   
Sbjct: 619 EEYLKFFDFTGMTLDQSLRYFFKAFSLVGETQERERVLIHFSNRYFYCNPDTIASQDGVH 678

Query: 825 SLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEI 884
            L  A+++LNTD H HN+ K+   MT +EF  NL+GVN G DF +D+L+ +Y++IKNE++
Sbjct: 679 CLTCAIMLLNTDLHGHNIGKK---MTCQEFIANLQGVNEGVDFSKDLLKALYNSIKNEKL 735


>gi|56790299 pleckstrin and Sec7 domain containing [Homo sapiens]
          Length = 1024

 Score =  101 bits (251), Expect = 8e-21
 Identities = 72/238 (30%), Positives = 122/238 (51%), Gaps = 28/238 (11%)

Query: 650 GRLPPEHGKSGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQ 709
           GR PP    S C   E+++  GA      +PP  S L+ D     E+ + ++L +  T+ 
Sbjct: 496 GREPP----SPCHS-EDSLGLGA-APLGSEPP-LSQLVSDSDS--ELDSTERLALGSTDT 546

Query: 710 FNQKPKKGIQFLQEKGLLTIPMDN---TEVAQWLRENPRLDKKMIGEFVSDRKNIDLLES 766
            +   K  ++  Q        +D     +VA+ L +N    K + GE++           
Sbjct: 547 LSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLK---------- 596

Query: 767 FVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSL 826
               F F G+ LD+ALR++L+   L GE    +R+L  F++R+  CN    ++ D   +L
Sbjct: 597 ---FFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTL 653

Query: 827 AYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEI 884
             A+++LNTD H HN+ K+   MT  +F  NL+G+N G DF +++L+ +Y +IKNE++
Sbjct: 654 TCALMLLNTDLHGHNIGKR---MTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKL 708


>gi|14150035 pleckstrin and Sec7 domain containing 2 [Homo sapiens]
          Length = 771

 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 54/150 (36%), Positives = 87/150 (58%), Gaps = 16/150 (10%)

Query: 735 EVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGE 794
           +VA+ L +N    + + GE++S              F F GL LD ALR +L+AF L GE
Sbjct: 331 DVARQLGKNNEFSRLVAGEYLS-------------FFDFSGLTLDGALRTFLKAFPLMGE 377

Query: 795 APVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEF 854
               +R+L  F+ R+  CN     + D   +L  A+++LNTD H HN+ K+   M+ ++F
Sbjct: 378 TQERERVLTHFSRRYCQCNPDDSTSEDGIHTLTCALMLLNTDLHGHNIGKK---MSCQQF 434

Query: 855 RKNLKGVNGGKDFEQDILEDMYHAIKNEEI 884
             NL  +N G+DF +D+L+ +Y++IKNE++
Sbjct: 435 IANLDQLNDGQDFAKDLLKTLYNSIKNEKL 464


>gi|56788370 pleckstrin and Sec7 domain containing 4 [Homo sapiens]
          Length = 1056

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 47/129 (36%), Positives = 78/129 (60%), Gaps = 5/129 (3%)

Query: 765 ESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACF 824
           E ++S F F G  LD ALR +L+A  L GE    +R+L  F+ R+ +CN   F + D+  
Sbjct: 622 EEYLSFFQFGGQSLDRALRSFLQALVLSGETQERERILYQFSRRFHHCNPGIFPSVDSVH 681

Query: 825 SLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEI 884
           +L  A+++LNTD H  N+ K    M+ +EF  NL G+  G +F +++L+ +Y +I++E++
Sbjct: 682 TLTCAIMLLNTDLHGQNIGKS---MSCQEFITNLNGLRDGGNFPKELLKALYWSIRSEKL 738

Query: 885 --VMPEEQT 891
              + EE T
Sbjct: 739 EWAVDEEDT 747


>gi|48928044 F-box only protein 8 [Homo sapiens]
          Length = 319

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 44/178 (24%), Positives = 88/178 (49%), Gaps = 14/178 (7%)

Query: 706 GTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLE 765
           G+  FN  P +G+ +   KG+L       E+A+++     L+ K +  ++ +R+  D+L+
Sbjct: 142 GSLTFNANPDEGVNYFMSKGIL--DDSPKEIAKFIFCTRTLNWKKLRIYLDERR--DVLD 197

Query: 766 SFVSTFSFQGLRLDEALRLYLEAFRLPGE-APVIQRLLEAFTERWMNCNGSPF----ANS 820
             V+  +F+   L  ALR +      P E    ++ L+  F+ R+  CN         + 
Sbjct: 198 DLVTLHNFRNQFLPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSP 257

Query: 821 DACFSLAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLK--GVNGGKDFEQDILEDMY 876
           DA + L Y++I+L+ D  + +V+ +   M+  EF +N +    N  +DF   + +++Y
Sbjct: 258 DAVYVLCYSLILLSIDLTSPHVKNK---MSKREFIRNTRRAAQNISEDFVGHLYDNIY 312


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 46/135 (34%), Positives = 58/135 (42%), Gaps = 14/135 (10%)

Query: 1730 PQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSE-LGACDFEKPESPRAASSSSPGSPVAS 1788
            P  Q P AS  LT+   +      PPP +  S  L     E P  P      +P SP+ +
Sbjct: 521  PSLQTPPAS--LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 1789 SP-----SRLSPTPDGPPPLAQPPLI------LQPLASPLQVGVPPMTLPIILNPALIEA 1837
             P     S  +P P  PP LA PPL       L PLA+P     P + LP +  P    A
Sbjct: 579  PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638

Query: 1838 TSPVPLLATPRPTDP 1852
            + P+  LATP P  P
Sbjct: 639  SPPLSPLATPSPQAP 653



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 40/130 (30%), Positives = 53/130 (40%), Gaps = 14/130 (10%)

Query: 1727 PMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPV 1786
            P  P    P+  A  +  A    +P   PP + P  L A   + P SP A+   SP +  
Sbjct: 664  PFSPPPSPPV-QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-- 720

Query: 1787 ASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLAT 1846
                   +P P  PPPLA PPL + P + P    + P   P    P L+ A    PL   
Sbjct: 721  -------TPPPQAPPPLAAPPLQVPP-SPPASPPMSPSATPPPRVPPLLAAP---PLQVP 769

Query: 1847 PRPTDPIPTS 1856
            P P   +P S
Sbjct: 770  PSPPASLPMS 779



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 42/133 (31%), Positives = 50/133 (37%), Gaps = 14/133 (10%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGS 1784
            P    P    P      +  A    +P   PPP+ P  L A   + P SP A   S P S
Sbjct: 692  PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA---SPPMS 748

Query: 1785 PVASSPSRLSPTPDGPPPLAQPP-----LILQPLASPLQVGVPPMTLPIILNPALIEATS 1839
            P A+ P R+ P     PPL  PP     L + PLA P     PP   P +  P L    S
Sbjct: 749  PSATPPPRVPPLL-AAPPLQVPPSPPASLPMSPLAKP-----PPQAPPALATPPLQALPS 802

Query: 1840 PVPLLATPRPTDP 1852
            P        P  P
Sbjct: 803  PPASFPGQAPFSP 815



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 17/143 (11%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGA----CDFEKPESPRAAS-- 1778
            P    P    P   A  +  A    +P   P P+ P+ L        F  P SP   +  
Sbjct: 618  PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 1779 ---SSSPGSPVASSPSRLSPTPDGPP------PLAQPPLILQPLASPLQVGVPPMTLPII 1829
               +S P SP A+ PS+  P+   PP      P A PP  + P A+P     PP+  P +
Sbjct: 678  SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP--MSPSATPPPQAPPPLAAPPL 735

Query: 1830 LNPALIEATSPVPLLATPRPTDP 1852
              P    A+ P+   ATP P  P
Sbjct: 736  QVPPSPPASPPMSPSATPPPRVP 758



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 25/121 (20%)

Query: 1755 PPPEIPSELGACDFEKPESPRAASS----SSPGSPVA------------------SSPSR 1792
            PP ++P  L +   + P SP A SS    +S GSP                    +SPSR
Sbjct: 387  PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446

Query: 1793 LSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDP 1852
             + TP   PPL Q PL L P + PLQ  + P   P + +P  I     +  LA+  P  P
Sbjct: 447  PASTPPDSPPL-QAPLSL-PASPPLQTSLSPAVSP-LSSPLTIHPLQALSSLASHSPQAP 503

Query: 1853 I 1853
            +
Sbjct: 504  L 504



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 47/157 (29%), Positives = 58/157 (36%), Gaps = 32/157 (20%)

Query: 1725 PMPMEPQGQKPLASAHLTS----AAGDTRTPGHP---PPPEIPSELGACDFEKPESPRAA 1777
            P P++     PL + HL +    A    + P  P   PPPE PS +     + P  P  A
Sbjct: 543  PPPLQT-ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP--PALA 599

Query: 1778 SSSSPGSPVASSPSRLSPTPDGPPPLAQPPLI----------LQPLASP----------- 1816
            S    G P        +P P  PP LA PPL           L PLA+P           
Sbjct: 600  SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659

Query: 1817 -LQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDP 1852
             LQ    P   P +  P    A+ PV   ATP    P
Sbjct: 660  LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 42/137 (30%), Positives = 54/137 (39%), Gaps = 28/137 (20%)

Query: 1739 AHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSP--- 1795
            A LTS +    TP   PP + P  L       P SP   +S SP     SSP  + P   
Sbjct: 439  ASLTSPSRPASTPPDSPPLQAPLSL-------PASPPLQTSLSPAVSPLSSPLTIHPLQA 491

Query: 1796 -------TPDGP-PPLAQPPLILQPLASPLQVGVPPMT--------LPIILNPALIEATS 1839
                   +P  P   L  PPL  Q   +P  +  PP +        LP +  P L  A++
Sbjct: 492  LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551

Query: 1840 PV--PLLATPRPTDPIP 1854
            P+  P L TP    P P
Sbjct: 552  PLTTPHLETPPCPAPCP 568



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 43/153 (28%), Positives = 56/153 (36%), Gaps = 35/153 (22%)

Query: 1730 PQGQKPLASAHL----TSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSP--- 1782
            PQ   PLA+  L    +  A    +P   PPP +P  L A   + P SP A+   SP   
Sbjct: 724  PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783

Query: 1783 -----------------GSPVASSPSR--------LSPTPDGPPPLAQPPLILQPLASPL 1817
                              SP AS P +        L  +P   PP   PP++  PL   L
Sbjct: 784  PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---L 840

Query: 1818 QVGVPPMTLPIILNPALIEATSPVPLLATPRPT 1850
            QV   P   P +  P       P   ++ PR T
Sbjct: 841  QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 42/152 (27%), Positives = 57/152 (37%), Gaps = 23/152 (15%)

Query: 1727 PMEPQGQKPLASAHLTSAAGDTRTPGHP----------PPPEIPSELGACDFEK-PESPR 1775
            PM P    P     L +A      P  P          PPP+ P  L     +  P  P 
Sbjct: 746  PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 1776 AASSSSPGSPVASSP-SRLSPTPDGPPPLAQPPLILQPLASPLQVGV-----PPMTLP-- 1827
            +    +P SP AS P S L+  P   PP+   PL+  P + P    +     PP   P  
Sbjct: 806  SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865

Query: 1828 IILNPALIEATSPVPLLATPRPTDPIPTSEVN 1859
             +  P L  A +P P    P P    P+S ++
Sbjct: 866  SVSGPRLTLALAPGP----PPPPSRSPSSTLS 893



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 5/106 (4%)

Query: 1750 TPGHPPPPEIPSELGACDFEKPESPRAASSSSPG-SPVASSPSRLSPTPDGPP--PLAQP 1806
            TP  P  P  P   G      P+       ++P   P++SSP   +P+P G    P+  P
Sbjct: 262  TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSGTKARPVPPP 320

Query: 1807 PLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDP 1852
                 PL + L    PP+  P+ L P    A   +  L +P  T P
Sbjct: 321  DNAATPLPATLPPS-PPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 20/127 (15%)

Query: 1743 SAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG--- 1799
            SA G  R P HP  P+ P  L A    +   PR  ++ + G P++SSP   +P+P G   
Sbjct: 258  SARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALG-PLSSSPLA-TPSPSGTKA 314

Query: 1800 ---PPP-----------LAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLA 1845
               PPP              PPL      +P     PP    +   PA   + +P  +  
Sbjct: 315  RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374

Query: 1846 TPRPTDP 1852
             P    P
Sbjct: 375  PPMQAPP 381



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 31/140 (22%)

Query: 1741 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSP-GSPVASSPSRLSPTPDG 1799
            ++SA+  + T   P     PS  G    ++P S   +SS++P  SP  S PS    TP  
Sbjct: 209  VSSASEHSTTEPSPAARRRPSAGGG--LQRPASRSLSSSATPLSSPARSGPSARG-TPRA 265

Query: 1800 PPPLAQP-------------------------PLILQPLASPLQVGVPPMTLPIILNPA- 1833
            P   +QP                         PL   PLA+P   G     +P   N A 
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 1834 -LIEATSPVPLLATPRPTDP 1852
             L     P P LATP P  P
Sbjct: 326  PLPATLPPSPPLATPLPLAP 345



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 23/147 (15%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGS 1784
            P+P       PL +    S    T  P  PP P  P  L       P  P    S +P S
Sbjct: 316  PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL----PSPPATPPSQAPPS 371

Query: 1785 PVASSPSRLSPTPDGPPPLAQP-------------PLILQPLASPLQVGVPPMTLP---I 1828
             + + P +  P+    PP+  P             PL L  L +   +G P +      +
Sbjct: 372  -MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430

Query: 1829 ILNPALIEA--TSPVPLLATPRPTDPI 1853
             ++P   +A  TSP    +TP  + P+
Sbjct: 431  TMSPRQTQASLTSPSRPASTPPDSPPL 457



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 1735 PLASAHL-TSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRL 1793
            PL+S+ L T +   T+    PPP    + L A     P SP  A+      P  S+P  L
Sbjct: 298  PLSSSPLATPSPSGTKARPVPPPDNAATPLPAT---LPPSPPLATPLPLAPPSPSAPPSL 354

Query: 1794 SPTPDGPPPLAQPPLILQP-------LASPLQVGVPPMTLP-IILNPALIEATSPVPL 1843
               P    P A PP    P        A P    +PP+ +P  + +P+L    SP+ L
Sbjct: 355  QTLPS---PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 47/151 (31%), Positives = 62/151 (41%), Gaps = 30/151 (19%)

Query: 1720 TVIQDPMPMEPQGQKPLASAHLT--SAAGDTRTPGH-------PPPPEIPSELGACDFEK 1770
            +V  D    E  G   L + +L   S+ GD R PG        PPPP  P+         
Sbjct: 98   SVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR-PGQYGQDLLIPPPPPGPA--------- 147

Query: 1771 PESPRAASSSSPGSPVASSPSRLSPTP----DGPPPLAQ---PPLILQPLASPLQVGVPP 1823
            P  P+  S    GSP+ S PS   P P    + PPP +    PP +L+ L+ P  +  P 
Sbjct: 148  PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS 207

Query: 1824 MTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
            +  P    P  I    P+  LA P P  P P
Sbjct: 208  IPTP----PDFIPPAPPLAFLAPPPPPVPAP 234



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 37/106 (34%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 1751 PGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLIL 1810
            P   P P+ P EL A     P SPR   S S     A +P    P P   PPL  P   L
Sbjct: 354  PDRAPEPDCPGELKAT---APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410

Query: 1811 QPLASPLQVGVPPMTLPIILNPALIEAT--SPVPLLATPRPTDPIP 1854
             P A PL     P        PA    T  S  P L  P+P  P P
Sbjct: 411  PPAAPPL-----PCAQKAAHPPAGFTKTPKSSSPAL-KPKPNPPSP 450



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 32/134 (23%), Positives = 48/134 (35%), Gaps = 18/134 (13%)

Query: 225 SKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF-----IDVPTPISSASS 279
           +KWK            T+ +P      P G+ L  N    + F     +  PTP+ ++S 
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSI 315

Query: 280 EAASAVVSPSTDSGL------------EFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 327
               A  +P  + G              F  +  S+       +P  PG   AT P S  
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375

Query: 328 LGVPE-QPDLQEGT 340
           LG  + Q D + GT
Sbjct: 376 LGQSQSQADERAGT 389



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/99 (31%), Positives = 34/99 (34%), Gaps = 21/99 (21%)

Query: 1729 EPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVAS 1788
            EP G  PL S   T+          PPPP +         E P  P  A    P     S
Sbjct: 156  EPPGGSPLPSPPSTAP---------PPPPLL--------LEPPPPPSMAPPPPPVLEALS 198

Query: 1789 SPSRLS----PTPDGPPPLAQPPLILQPLASPLQVGVPP 1823
             P  LS    PTP    P A P   L P   P+    PP
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 47/151 (31%), Positives = 62/151 (41%), Gaps = 30/151 (19%)

Query: 1720 TVIQDPMPMEPQGQKPLASAHLT--SAAGDTRTPGH-------PPPPEIPSELGACDFEK 1770
            +V  D    E  G   L + +L   S+ GD R PG        PPPP  P+         
Sbjct: 98   SVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR-PGQYGQDLLIPPPPPGPA--------- 147

Query: 1771 PESPRAASSSSPGSPVASSPSRLSPTP----DGPPPLAQ---PPLILQPLASPLQVGVPP 1823
            P  P+  S    GSP+ S PS   P P    + PPP +    PP +L+ L+ P  +  P 
Sbjct: 148  PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS 207

Query: 1824 MTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
            +  P    P  I    P+  LA P P  P P
Sbjct: 208  IPTP----PDFIPPAPPLAFLAPPPPPVPAP 234



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 37/106 (34%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 1751 PGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLIL 1810
            P   P P+ P EL A     P SPR   S S     A +P    P P   PPL  P   L
Sbjct: 354  PDRAPEPDCPGELKAT---APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410

Query: 1811 QPLASPLQVGVPPMTLPIILNPALIEAT--SPVPLLATPRPTDPIP 1854
             P A PL     P        PA    T  S  P L  P+P  P P
Sbjct: 411  PPAAPPL-----PCAQKAAHPPAGFTKTPKSSSPAL-KPKPNPPSP 450



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 32/134 (23%), Positives = 48/134 (35%), Gaps = 18/134 (13%)

Query: 225 SKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF-----IDVPTPISSASS 279
           +KWK            T+ +P      P G+ L  N    + F     +  PTP+ ++S 
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSI 315

Query: 280 EAASAVVSPSTDSGL------------EFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 327
               A  +P  + G              F  +  S+       +P  PG   AT P S  
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375

Query: 328 LGVPE-QPDLQEGT 340
           LG  + Q D + GT
Sbjct: 376 LGQSQSQADERAGT 389



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/99 (31%), Positives = 34/99 (34%), Gaps = 21/99 (21%)

Query: 1729 EPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVAS 1788
            EP G  PL S   T+          PPPP +         E P  P  A    P     S
Sbjct: 156  EPPGGSPLPSPPSTAP---------PPPPLL--------LEPPPPPSMAPPPPPVLEALS 198

Query: 1789 SPSRLS----PTPDGPPPLAQPPLILQPLASPLQVGVPP 1823
             P  LS    PTP    P A P   L P   P+    PP
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 12/131 (9%)

Query: 1722 IQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSS 1781
            ++ P    P+     A   L+S+   T +P  PP P  P  L       P +P + +++S
Sbjct: 271  LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP-SPPATPPSQATTS 329

Query: 1782 PGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPV 1841
             GSP   +     P+P            L PLA+P     P + LP +  P    A+ P+
Sbjct: 330  LGSPTLQATHSFLPSPP-----------LSPLATPPPQAPPALALPPLQAPPSPPASPPL 378

Query: 1842 PLLATPRPTDP 1852
              LATP P  P
Sbjct: 379  SPLATPSPQAP 389



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 41/116 (35%), Positives = 54/116 (46%), Gaps = 12/116 (10%)

Query: 1743 SAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPP 1802
            SA G  R P HP  P+ P  L A    +   PR  ++ + G P++SSP   +P+P  PP 
Sbjct: 249  SARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALG-PLSSSPLA-TPSPSAPPS 305

Query: 1803 LAQPPLILQPLASPLQVGVPPMTLPIILNPALIEAT------SPVPLLATPRPTDP 1852
             + PP  LQ L SP     PP      L    ++AT       P+  LATP P  P
Sbjct: 306  PSAPP-SLQTLPSP--PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 8/138 (5%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGS 1784
            P    P    P      +  A    +P   PPP+ P  L A   +  + P  A  +    
Sbjct: 428  PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487

Query: 1785 PVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSP--VP 1842
            P+ + PS  +  P   P      L + PLA+P     PP   P++  P L    SP   P
Sbjct: 488  PLQALPSPPASFPGQAPFSPSASLPMSPLATP-----PPQAPPVLAAPLLQVPPSPPASP 542

Query: 1843 LLATP-RPTDPIPTSEVN 1859
             L  P RP  P P + V+
Sbjct: 543  TLQAPRRPPTPGPDTSVS 560



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 43/150 (28%), Positives = 57/150 (38%), Gaps = 22/150 (14%)

Query: 1725 PMPMEPQGQK-PLASAHLTSAAGDTRTPGHPPPPEIPSELGA----CDFEKPESPRAAS- 1778
            P P  P     P   A  +  A    +P   P P+ P+ L        F  P SP   + 
Sbjct: 353  PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412

Query: 1779 ----SSSPGSPVASSPSRLSPTPDGPP------PLAQPPLILQPLASPLQVGVPPMTLPI 1828
                +S P SP A+ PS+  P+   PP      P A PP  + P A+P     PP+  P 
Sbjct: 413  FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP--MSPSATPPPQAPPPLAAPP 470

Query: 1829 IL----NPALIEATSPVPLLATPRPTDPIP 1854
            +      P    A +  PL A P P    P
Sbjct: 471  LQLAKPPPQAPPALATPPLQALPSPPASFP 500



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 41/139 (29%), Positives = 56/139 (40%), Gaps = 22/139 (15%)

Query: 1730 PQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEK-PESPRAASSSSPGSPVAS 1788
            PQ   PLA+  L  A          PPP+ P  L     +  P  P +    +P SP AS
Sbjct: 460  PQAPPPLAAPPLQLAK---------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510

Query: 1789 SP-SRLSPTPDGPPPLAQPPLILQPLASPLQVGV-----PPMTLP--IILNPALIEATSP 1840
             P S L+  P   PP+   PL+  P + P    +     PP   P   +  P L  A +P
Sbjct: 511  LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570

Query: 1841 VPLLATPRPTDPIPTSEVN 1859
             P    P P    P+S ++
Sbjct: 571  GP----PPPPSRSPSSTLS 585



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 40/114 (35%), Positives = 53/114 (46%), Gaps = 12/114 (10%)

Query: 1741 LTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSP-GSPVASSPSRLSPTPDG 1799
            ++SA+  + T   P     PS  G    ++P S   +SS++P  SP  S PS    TP  
Sbjct: 200  VSSASEHSTTEPSPAARRRPSAGGG--LQRPASRSLSSSATPLSSPARSGPSARG-TPRA 256

Query: 1800 PPPLAQP-PLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDP 1852
            P   +QP P  LQ L  P QV  P       L P    ++SP   LATP P+ P
Sbjct: 257  PAHPSQPKPKGLQALRPP-QVTPPRKDAAPALGPL---SSSP---LATPSPSAP 303


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
          Length = 1188

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 47/151 (31%), Positives = 62/151 (41%), Gaps = 30/151 (19%)

Query: 1720 TVIQDPMPMEPQGQKPLASAHLT--SAAGDTRTPGH-------PPPPEIPSELGACDFEK 1770
            +V  D    E  G   L + +L   S+ GD R PG        PPPP  P+         
Sbjct: 98   SVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR-PGQYGQDLLIPPPPPGPA--------- 147

Query: 1771 PESPRAASSSSPGSPVASSPSRLSPTP----DGPPPLAQ---PPLILQPLASPLQVGVPP 1823
            P  P+  S    GSP+ S PS   P P    + PPP +    PP +L+ L+ P  +  P 
Sbjct: 148  PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPS 207

Query: 1824 MTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
            +  P    P  I    P+  LA P P  P P
Sbjct: 208  IPTP----PDFIPPAPPLAFLAPPPPPVPAP 234



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 37/106 (34%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 1751 PGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLIL 1810
            P   P P+ P EL A     P SPR   S S     A +P    P P   PPL  P   L
Sbjct: 354  PDRAPEPDCPGELKAT---APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410

Query: 1811 QPLASPLQVGVPPMTLPIILNPALIEAT--SPVPLLATPRPTDPIP 1854
             P A PL     P        PA    T  S  P L  P+P  P P
Sbjct: 411  PPAAPPL-----PCAQKAAHPPAGFTKTPKSSSPAL-KPKPNPPSP 450



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 32/134 (23%), Positives = 48/134 (35%), Gaps = 18/134 (13%)

Query: 225 SKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPF-----IDVPTPISSASS 279
           +KWK            T+ +P      P G+ L  N    + F     +  PTP+ ++S 
Sbjct: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSI 315

Query: 280 EAASAVVSPSTDSGL------------EFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSE 327
               A  +P  + G              F  +  S+       +P  PG   AT P S  
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375

Query: 328 LGVPE-QPDLQEGT 340
           LG  + Q D + GT
Sbjct: 376 LGQSQSQADERAGT 389



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/99 (31%), Positives = 34/99 (34%), Gaps = 21/99 (21%)

Query: 1729 EPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVAS 1788
            EP G  PL S   T+          PPPP +         E P  P  A    P     S
Sbjct: 156  EPPGGSPLPSPPSTAP---------PPPPLL--------LEPPPPPSMAPPPPPVLEALS 198

Query: 1789 SPSRLS----PTPDGPPPLAQPPLILQPLASPLQVGVPP 1823
             P  LS    PTP    P A P   L P   P+    PP
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPP 237


>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1687

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1747 DTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQP 1806
            D  TP     PE   E G+      E P    +  P  PV   PS +  +P  P P A P
Sbjct: 949  DLATPSEAKKPE--EEAGSS-----EQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATP 1001

Query: 1807 PLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
                QPL  P+Q+ VP  +  ++ +P L+ +++ +   A  RP  P P
Sbjct: 1002 EPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKP 1049


>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 7/108 (6%)

Query: 1747 DTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQP 1806
            D  TP     PE   E G+      E P    +  P  PV   PS +  +P  P P A P
Sbjct: 949  DLATPSEAKKPE--EEAGSS-----EQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATP 1001

Query: 1807 PLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
                QPL  P+Q+ VP  +  ++ +P L+ +++ +   A  RP  P P
Sbjct: 1002 EPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKP 1049


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 43/134 (32%), Positives = 50/134 (37%), Gaps = 10/134 (7%)

Query: 1720 TVIQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASS 1779
            + + DP    P+         L  AA     PG PP P +PS   A     PE P     
Sbjct: 1403 SALDDPPLAGPKDTSTPDGPPLAPAAA---VPGPPPLPGLPS---ANSNGTPEPPLLEEK 1456

Query: 1780 SSPGSPVASSPSRLSPTPDGPPPLAQPPL-ILQPLASPLQVGVPPMTLPIILNPALIEAT 1838
              P  P A +P    P P  PPP  QP L    PL +P     PP  LP    PA+    
Sbjct: 1457 PPPTPPPAPTP---QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513

Query: 1839 SPVPLLATPRPTDP 1852
             P P  A P    P
Sbjct: 1514 PPPPPAAAPLAAPP 1527



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 38/117 (32%), Positives = 42/117 (35%), Gaps = 28/117 (23%)

Query: 1747 DTRTPGHPP---------PPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTP 1797
            DT TP  PP         PP +P    A     PE P       P  P A +P    P P
Sbjct: 1415 DTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ---PQP 1471

Query: 1798 DGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIP 1854
              PPP  QP L      SP     PP+  P   +P       P PL   P P  P P
Sbjct: 1472 PPPPPPPQPAL-----PSP-----PPLVAPTPSSP------PPPPLPPPPPPAMPSP 1512



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 14/120 (11%)

Query: 1718 KQTVIQDPMPMEPQ----GQKPLASAHLTSAAGDTRTP---GHPPPPEIPSELGACDFEK 1770
            K T   D  P+ P     G  PL      ++ G    P     PPP   P+         
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP 1473

Query: 1771 PESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQ-------PPLILQPLASPLQVGVPP 1823
            P  P   +  SP   VA +PS   P P  PPP          PP    PLA+P +    P
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 39/135 (28%), Positives = 49/135 (36%), Gaps = 11/135 (8%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPE--IPSELGACDFEKPESPRAASSSSP 1782
            P P   Q  +P     L  A G       PPPP   +PS L       P      S+S  
Sbjct: 766  PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSP------SASKV 819

Query: 1783 GSPVASSPSR-LSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNP--ALIEATS 1839
            G  +    +R  +P P  PPP   PP+ LQ  A     G+ P      L P  +L    +
Sbjct: 820  GVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA 879

Query: 1840 PVPLLATPRPTDPIP 1854
               LL    P  P P
Sbjct: 880  MQELLGALEPLPPAP 894



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 4/71 (5%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGS 1784
            P+P+   GQ     +   S+A   + P  PP PE P +  +   EKP   +   ++ P  
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTS---EKPPE-QTPETAMPEP 1726

Query: 1785 PVASSPSRLSP 1795
            P    PS L P
Sbjct: 1727 PAPEKPSLLRP 1737



 Score = 31.6 bits (70), Expect = 7.5
 Identities = 39/140 (27%), Positives = 50/140 (35%), Gaps = 24/140 (17%)

Query: 1732 GQKPLASAHLTSAAGDTRTPGHPPPP-----------EIPSELGACDFEKPESPRAASSS 1780
            GQ    S   + + G  + P  PPPP           ++  +L     E    P A S  
Sbjct: 464  GQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQG 523

Query: 1781 SP-GSPVASSPSRLSPTPDG------PPPL-----AQPPLILQPLASPLQVGVPP-MTLP 1827
             P  SP  S  +  SP   G      P  L     A P  I++PL SP   G PP +  P
Sbjct: 524  LPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSP 583

Query: 1828 IILNPALIEATSPVPLLATP 1847
                  L    +  P LA P
Sbjct: 584  GAPGKYLSSVLASAPFLAPP 603


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
            sapiens]
          Length = 483

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 7/130 (5%)

Query: 1728 MEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVA 1787
            + P GQ+ +A        G        P P +P++  +     P SPR  ++S       
Sbjct: 109  LRPAGQRDVAGGKTGQGPGS-----RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAAR 163

Query: 1788 SSPSRLS-PTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATS-PVPLLA 1845
            ++P R + P P  P P   PP +  PL S   +  P ++ P  L    +   + PVP   
Sbjct: 164  TAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223

Query: 1846 TPRPTDPIPT 1855
             P P  P PT
Sbjct: 224  PPPPPPPPPT 233



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 9/108 (8%)

Query: 1722 IQDPMPMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSS 1781
            I  P+P+ P    P   A   S A D + P  PPPP  P    +C      SPRA+  + 
Sbjct: 260  IPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP--YASC------SPRASLPAP 311

Query: 1782 PGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPII 1829
            P   V SS     P P   P    PP      A P     PP + P +
Sbjct: 312  PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP-PAPPGSQPFL 358



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 5/95 (5%)

Query: 1750 TPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLI 1809
            TP  PPPP  P    +   + P        +    PV + P   +P P  PPP   PP  
Sbjct: 178  TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP-P 236

Query: 1810 LQPLASPLQVGVPPMTLPIILNPALIEATSPVPLL 1844
            L P +      V P   P+ L P       P+PLL
Sbjct: 237  LPPASVLSDKAVKPQLAPLHLPP----IPPPLPLL 267


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 44/146 (30%), Positives = 56/146 (38%), Gaps = 25/146 (17%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHP-------PPPEIPSELGACDFEKPESPRAA 1777
            P P EP           TS A    TP  P       PPPE P+   A     PE P + 
Sbjct: 1008 PTPEEP-----------TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA-VPTPEEPTSP 1055

Query: 1778 SSSSPGSPVASSPSRLSPTPDGP-PPLAQPPLILQPLASPLQVGVP-PMTLPIILNPALI 1835
            +++ P     +SP+   PTP+ P  P A  P   +P +    V  P   T P    P   
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115

Query: 1836 EATSPVPLLATPR----PTDPIPTSE 1857
            E  SP   + TP     P   +PT E
Sbjct: 1116 EPASPAAAVPTPEEPASPAAAVPTPE 1141



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 41/128 (32%), Positives = 54/128 (42%), Gaps = 14/128 (10%)

Query: 1743 SAAGDTRTPGHP-------PPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSP 1795
            +AA    TP  P       P PE P+   A     PE P + +++ P     +SP+   P
Sbjct: 989  TAAVRVSTPEEPASPAAAVPTPEEPTSPAAA-VPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047

Query: 1796 TPDGP-PPLAQPPLILQPLASPLQVGVP-PMTLPIILNPALIEATSPVPLLATP-RPTDP 1852
            TP+ P  P A  P   +P +    V  P   T P    P   E TSP   + TP  PT P
Sbjct: 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1107

Query: 1853 ---IPTSE 1857
               +PT E
Sbjct: 1108 AAAVPTPE 1115



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 42/119 (35%), Positives = 50/119 (42%), Gaps = 16/119 (13%)

Query: 1748 TRTPGHPPPPEIPSELGACDFEKPESPRAASS--SSPGSPVASSPSRLSPTPDGP-PPLA 1804
            T   G P  P  P    A     PE P  A+   S+P  P  +SP+   PTP+ P  P A
Sbjct: 965  TEEDGTPEGPVTP----ATTVHAPEEPDTAAVRVSTPEEP--ASPAAAVPTPEEPTSPAA 1018

Query: 1805 QPPLILQPLASPLQVGVPP--MTLPIILNPALIEATSPVPLLATP-RPTDP---IPTSE 1857
              P   +P  SP     PP   T P    P   E TSP   + TP  PT P   +PT E
Sbjct: 1019 AVPTPEEP-TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 12/124 (9%)

Query: 1725 PMPMEPQGQKPLASAHLTSAAGDTRTPGHP-PPPEIPSELGAC--DFEKPESPRAASSSS 1781
            P    P  ++P +SA       +  +P    P PE P+   A   + E+P SP AA    
Sbjct: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAV--- 1300

Query: 1782 PGSPVASSPSRLSPTPDGP--PPLAQPPL-ILQPLASP-LQVGVPPMTLPIIL--NPALI 1835
            P   VA+ P+   PTP+ P  P  A PP+  + P+  P L V     ++PI     P L 
Sbjct: 1301 PTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360

Query: 1836 EATS 1839
            EA+S
Sbjct: 1361 EASS 1364



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 20/148 (13%)

Query: 1725 PMPMEPQGQKPLASAHL----TSAAGDTRTPGHP-------PPPEIPSELGACDFEKPES 1773
            P P EP    P A+       TS A    TP  P       P PE P+   A     PE 
Sbjct: 1060 PTPEEPTS--PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA-VPTPEE 1116

Query: 1774 PRAASSSSPGSPVASSPSRLSPTPDGPP-PLAQPPLILQPLASPLQVGVPPMTL-PIILN 1831
            P + +++ P     +SP+   PTP+ P  P    P   +  ++ + V  P  +  P    
Sbjct: 1117 PASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176

Query: 1832 PALIEATSPVPLLAT-PRPTDP---IPT 1855
            P   E+ S   ++AT   PT P   +PT
Sbjct: 1177 PTPAESASFAAVVATLEEPTSPAASVPT 1204



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 14/136 (10%)

Query: 233  SPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDS 292
            +P  P       P  E PT     + +      P   VPTP   AS   A+AV +P   +
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS--PAAAVPTPEEPA 1131

Query: 293  GLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGV----PEQPDLQEGTHVEKSQSA 348
                +  T         E+P  P  +  T   S+   V    PE+           ++SA
Sbjct: 1132 SPAAAVPTP--------EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183

Query: 349  SVESIPEVLEECTSPA 364
            S  ++   LEE TSPA
Sbjct: 1184 SFAAVVATLEEPTSPA 1199



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 14/136 (10%)

Query: 233  SPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDS 292
            +P  P       P  E PT     + +      P   VPTP    S   A+AV +P    
Sbjct: 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS--PAAAVPTP---- 1101

Query: 293  GLEFSSQTTSKEDLTDLEQPGSPGYSTAT--EPGSSELGV--PEQPDLQEGTHVEKSQSA 348
                   T+    +   E+P SP  +  T  EP S    V  PE+P           +SA
Sbjct: 1102 ----EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESA 1157

Query: 349  SVESIPEVLEECTSPA 364
            S        EE  SPA
Sbjct: 1158 SAAVAVPTPEESASPA 1173



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 39/139 (28%), Positives = 50/139 (35%), Gaps = 13/139 (9%)

Query: 233  SPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDS 292
            +P  P       P  E        + +      P   VPTP  SAS  A  A +   T  
Sbjct: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198

Query: 293  GLEFSSQTTSKEDLTDLEQPGSPGYS--TATEPGSSELGV-----PEQPDLQEGTHVEKS 345
                +S  T    +  LE+  SP  S  T+ EP S    V     P  P     T  E +
Sbjct: 1199 A---ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT 1255

Query: 346  QSASVESIPEVLEECTSPA 364
             SA+    P   EE +SPA
Sbjct: 1256 SSAAAVLTP---EELSSPA 1271



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 40/141 (28%), Positives = 54/141 (38%), Gaps = 26/141 (18%)

Query: 1727 PMEPQGQKPLASAHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPV 1786
            P  P    P  +A + +    T      P  E P+ L            AA+ S+P  P 
Sbjct: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASL------------AAAVSNPEEP- 1241

Query: 1787 ASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPIILNPA-----LIEATSPV 1841
             +SP+   PT + P   A   L  + L+SP    VP    P   +PA     L E  SP 
Sbjct: 1242 -TSPAAAVPTLEEPTSSAAAVLTPEELSSP-AASVPTPEEP--ASPAAAVSNLEEPASPA 1297

Query: 1842 PLLATPR----PTDPIPTSEV 1858
              + TP     P   +PT EV
Sbjct: 1298 AAVPTPEVAAIPAASVPTPEV 1318



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 32/130 (24%), Positives = 44/130 (33%), Gaps = 2/130 (1%)

Query: 233  SPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDS 292
            +P  P       P  E PT +   + +      P   VPTP   AS  AA + +      
Sbjct: 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296

Query: 293  GLEFSSQTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVES 352
                 +   +      +  P  P    A  P   E+     P L    H + S   S E 
Sbjct: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTD-SVPISEEG 1355

Query: 353  IPEVLEECTS 362
             P VLEE +S
Sbjct: 1356 TP-VLEEASS 1364


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,325,284
Number of Sequences: 37866
Number of extensions: 3908494
Number of successful extensions: 23891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 772
Number of HSP's that attempted gapping in prelim test: 18481
Number of HSP's gapped (non-prelim): 4641
length of query: 1859
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1742
effective length of database: 13,817,196
effective search space: 24069555432
effective search space used: 24069555432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.