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Search of human proteins with 4758220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758220 XAP-5 protein [Homo sapiens]
(339 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758220 XAP-5 protein [Homo sapiens] 674 0.0
gi|6912326 family with sequence similarity 50, member B [Homo sa... 518 e-147
gi|221219020 NYD-SP11 protein [Homo sapiens] 64 3e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 63 4e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 6e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 6e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 60 2e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 60 3e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 60 4e-09
gi|92859701 myosin VI [Homo sapiens] 59 6e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 58 1e-08
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 58 1e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 58 1e-08
gi|148746195 trichohyalin [Homo sapiens] 58 1e-08
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 58 1e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 56 4e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 56 4e-08
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 56 5e-08
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 55 7e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 9e-08
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 55 1e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 2e-07
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 54 2e-07
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 54 2e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 54 2e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 54 2e-07
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 2e-07
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 2e-07
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 2e-07
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 674 bits (1738), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 60
MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL
Sbjct: 1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 60
Query: 61 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 120
KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL
Sbjct: 61 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 120
Query: 121 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180
SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR
Sbjct: 121 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180
Query: 181 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240
EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE
Sbjct: 181 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240
Query: 241 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 300
LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE
Sbjct: 241 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 300
Query: 301 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339
SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
Sbjct: 301 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339
>gi|6912326 family with sequence similarity 50, member B [Homo
sapiens]
Length = 325
Score = 518 bits (1334), Expect = e-147
Identities = 252/339 (74%), Positives = 296/339 (87%), Gaps = 14/339 (4%)
Query: 1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 60
MAQYKG EAGRAMHL+KKRE+QREQME +KQRIAEE I+KS +DK+FSAHYDAVEAEL
Sbjct: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
Query: 61 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 120
KSSTVGLVTLNDMKA+QEALV+ERE+QLAK++ +E +++ E+ RE+E+++E KRKIS L
Sbjct: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
Query: 121 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180
SF L++ ++ + E + LGKNPDVDTSFLPDRDREEEENRLR
Sbjct: 121 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR 166
Query: 181 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240
EELRQEWEA++EK+K EE+E+TFSYWDGSGHRRTV++RKGNT+QQFL+KAL+ LRKDF E
Sbjct: 167 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE 226
Query: 241 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 300
LRSAGVEQLM+IKEDLI+PH+H+FYDFI+ +ARGKSGPLF+FDVHDDVRLLSDAT+EKDE
Sbjct: 227 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE 286
Query: 301 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339
SHAGKVVLRSWYEKNKHIFPASRWE YDPEKKWDKYTIR
Sbjct: 287 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR 325
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/203 (27%), Positives = 105/203 (51%), Gaps = 23/203 (11%)
Query: 47 KKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLRE 106
+KFS+ D VE+E S + +L D KQE+L E E++ ++E+ +E +++ E+
Sbjct: 2211 EKFSSQVDEVESEEHFSEE-MESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 107 KERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSF 166
KE ++ ++++ E+EEE +++++ EE E+EE+ +K ++ + +T
Sbjct: 2270 KEEEEGEEKQV-------EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI--MSEEETES 2320
Query: 167 LPDRDREEEENRLREELRQEWE--AKQEKIKSEE--------IEITFSYWDGSGHRRTVK 216
L D + EEE L EE+ +E E K+++ K +E E S G H +
Sbjct: 2321 LSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRA 2380
Query: 217 MRKG---NTMQQFLQKALEILRK 236
+R G + +++ + ALE+ K
Sbjct: 2381 IRLGVLKSPLKKLMSTALEMKEK 2403
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/209 (24%), Positives = 95/209 (45%), Gaps = 37/209 (17%)
Query: 72 DMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERK---KEAKRKISSLSFTLEEEE 128
D K+ L K+ EK+LA+K+ ++L K+ ++ KE K +E+K L++EE
Sbjct: 2124 DFSEKRSELTKD-EKKLARKQ--RKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEE 2180
Query: 129 EGGEEEEEAAMY-----------------------------EEEMEREEITTKKRKLGKN 159
EGG EEEE + EE EE+ + +L K
Sbjct: 2181 EGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQ 2240
Query: 160 PDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRK 219
+ + + +REEEE R EE+R+E E ++E+ + EE ++ + ++ K +
Sbjct: 2241 ESLSSE--EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Query: 220 GNTMQQFLQKALEILRKDFSELRSAGVEQ 248
++ ++ EI+ ++ +E S E+
Sbjct: 2299 VQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Score = 55.1 bits (131), Expect = 9e-08
Identities = 41/166 (24%), Positives = 80/166 (48%), Gaps = 16/166 (9%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
K+ +K +E+ + E + ++ + D +E + S+ + + ++E
Sbjct: 2204 KRGDKPKEKFSSQVDEVESEE----HFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKR-KISSLSFTLEEEEE-------- 129
V+E E++ ++E+ +E Q++ E+ +K++KKE K+ ++ EE+EE
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Query: 130 ---GGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR 172
EEEEE+ EEE++RE+ KK K K + L R+R
Sbjct: 2320 SLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/235 (19%), Positives = 111/235 (47%), Gaps = 22/235 (9%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKA 75
KKR ++ ++ Q ++++A+E + ++K + Y + + E+ + + A
Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA 1645
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKEAKRKISSLSFTL--------EE 126
++ + + ++LA+K K+L K EK+ RE+E+ + K++ + L +
Sbjct: 1646 QRGEKLSQEAEKLAQKR--KKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Query: 127 EEEGGEEEEEAAMYEEEME--REEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELR 184
E+ +E+E A EE+E EE++ K+ +L + + + ++ + EE R
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEELNQE---EGKLVEEKKKLAEEEEALAWQR 1760
Query: 185 QEWEAKQEKIKSEEIEITFSYWDGSGHRRTV---KMRKGNTMQQFLQKALEILRK 236
++ ++ K+ EE + + H+ + + R G +Q ++K +++ +K
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK 1815
Score = 43.1 bits (100), Expect = 4e-04
Identities = 43/200 (21%), Positives = 96/200 (48%), Gaps = 22/200 (11%)
Query: 15 MHLMKKREKQREQMEQMKQRIAE--ENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
++ K ++++ + Q K+++A+ EN++ +K+ H ++K+ L N
Sbjct: 1833 LYQKKNLAQEKKNLAQEKEKLAQRKENLL---YNKERLTHSKKQLVQVKNK---LGMFNK 1886
Query: 73 MKAK-QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGG 131
+ A+ +E L +E+E + KKE+ E + KL ++ + KK+ K + LE+ G
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946
Query: 132 EE---------EEEAAMYEEEMEREEITTKKRKLGKNPD-VDTSFLPDRDREEEENRLRE 181
++ +EE A+ +E + + +K +L + + + P+ R+ + ++ +
Sbjct: 1947 KKRLRGELDIAKEEKAL---NLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQ 2003
Query: 182 ELRQEWEAKQEKIKSEEIEI 201
EL + + +EKI E I
Sbjct: 2004 ELFERKLSLEEKILLHEDRI 2023
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/218 (24%), Positives = 88/218 (40%), Gaps = 21/218 (9%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ KK EK+ Q + R A + K K E ++ + TL + K
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKA---VQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVK 1443
Query: 77 QEALVKEREK----QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
QE + E+ Q KK + Q+ E + + KE K L +EEE
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEK------RLLQEEEKLH 1497
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDRE-----EEENRLREELRQEW 187
+ E EEEM +E+ KK K + V + L + +E EEE L EE+ +E
Sbjct: 1498 QAGEKLSPEEEMLQED---KKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREG 1554
Query: 188 EAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQ 225
E K++++ E+ I + HR+ + K ++
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKAK 76
K ++ E + Q +++++E + KK + ++ V E +L L + ++ A+
Sbjct: 1636 KFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQ 1695
Query: 77 QEALVKERE-------KQLAKKEQS-----KELQMKLEKLREKERK-KEAKRKISSLSFT 123
+ + +RE K+LA++ + +EL K E+L ++E K E K+K++
Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755
Query: 124 LEEEEEGGEEEEEAAMYEEEM---EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180
L + E EEE EEE+ E+E++ K K+ P+ + R++ E+
Sbjct: 1756 LAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM---PEEEERLGRKREQLIEKKMKL 1812
Query: 181 EELRQEWEAKQEKIKSEEI 199
+ R+ W E++ ++
Sbjct: 1813 AQKRERWINSMEELTKNKM 1831
Score = 36.2 bits (82), Expect = 0.043
Identities = 40/186 (21%), Positives = 87/186 (46%), Gaps = 10/186 (5%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAE--LKSSTVGLVTLNDMKAK-Q 77
R+ + E+ ++R+ +E +K S + ++ + LK V N + +K +
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK 1534
Query: 78 EALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
E K+ E+ ++E S+E + K +++ E++R + + K + + E+ +EE
Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK 1594
Query: 138 AMYEEE---MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKI 194
EEE E ++ ++RKL + T DR+ + E + + ++E A++ +
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYVKITQ--DDREMAQAEGKFAQ--KEETLAQRGEK 1650
Query: 195 KSEEIE 200
S+E E
Sbjct: 1651 LSQEAE 1656
Score = 29.6 bits (65), Expect = 4.0
Identities = 35/163 (21%), Positives = 74/163 (45%), Gaps = 18/163 (11%)
Query: 53 YDAVEAELKSSTV--GLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKER- 109
+D V E K + G + + ++ + +++ +E ++EQ+++ + L E +
Sbjct: 1307 WDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVI 1366
Query: 110 KKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPD 169
K+ K+ I + +E ++EE+ + + + K+RK+GK
Sbjct: 1367 LKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGK---------IK 1417
Query: 170 RDREEEENRLREELRQEWEAKQEKIKSEE-----IEITFSYWD 207
R+ +EE + EE+ +E +EK+ +E IE T S+ D
Sbjct: 1418 REMTKEERDMSEEV-EEMATLEEKVVKQEGKLVMIERTPSWQD 1459
Score = 29.3 bits (64), Expect = 5.3
Identities = 49/253 (19%), Positives = 107/253 (42%), Gaps = 35/253 (13%)
Query: 23 KQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVK 82
K+ + + +R+AEE + + S + + T L + K E +
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017
Query: 83 EREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEE 142
E ++ E+S+ + KLE R + + +RK++ S L ++ E ++ +E
Sbjct: 2018 LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRE--------SLSKE 2069
Query: 143 EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIEIT 202
+ +I +KL ++ +R +EE ++ ++++ K+ ++ E+ ++
Sbjct: 2070 PAKLNKILKALQKLTRD---------ERKLTQEEIKM-TKMKRALFVKERRLSIEQSKLD 2119
Query: 203 FSYWDGSGHRRTV---------KMRK-GNTMQQFLQKALEILRKDFSELRSAGVEQLM-- 250
WD S R + K RK N M++ + K E + ++ S+L E ++
Sbjct: 2120 IKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKE-EKMTEEESKLARKHSEVILDD 2178
Query: 251 ----YIKEDLIIP 259
I+E+ +IP
Sbjct: 2179 EEEGGIEEEEVIP 2191
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 62.8 bits (151), Expect = 4e-10
Identities = 52/243 (21%), Positives = 118/243 (48%), Gaps = 18/243 (7%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+K ++Q E++ + +++I ++ M K + + +++ + + QE
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR------QEKMREQEDQMWEQEEKMRDQE 557
Query: 79 ALVKEREKQLAKK--EQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
+ ++E+++ KK EQ K+ + EK+RE+ER +E ++K+ + E+EE +E+EE
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWE----AKQE 192
+EE E+ + + K + + ++ E+ RL E+ + WE +QE
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 193 KIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQLMYI 252
K++ +E +I W+ + + ++ T Q + E +R+ ++R E++M
Sbjct: 678 KMQEQEEKI----WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE--EEMMRE 731
Query: 253 KED 255
+E+
Sbjct: 732 QEE 734
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/194 (25%), Positives = 101/194 (52%), Gaps = 16/194 (8%)
Query: 19 KKREKQREQMEQMKQRIAE-ENIMKSNIDKKF--SAHYDAVEAELKSSTVGLVTLNDMKA 75
KK KQ E+M + ++R+ E E M+ +K + E EL+ L +++
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
++E + ++ EK ++E+ +E + K+ R++ER E ++++ + ++EE E++
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKM--WRQEERLWEQEKQMREQEQKMRDQEERMWEQD 403
Query: 136 EAAMYEEE--MEREEITTKKRKLGKNPDVDTSFLPDRDREE---EENRLRE---ELRQEW 187
E +EE E+E++ + K+ + + RD+EE EE R+RE ++R+E
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE 463
Query: 188 EA---KQEKIKSEE 198
E ++EK++ +E
Sbjct: 464 ETMREQEEKMQKQE 477
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/220 (22%), Positives = 116/220 (52%), Gaps = 30/220 (13%)
Query: 23 KQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVK 82
+Q E++ + ++R+ E+ M ++K E E K+ + K ++E ++
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEK-MREEKKMQEQEKKTRD------QEEKMQEEERIR 453
Query: 83 EREKQLAK-----KEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
EREK++ + +EQ +++Q + E + E+E K+ ++++ L E+E+ E+EE+
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 138 AMYEEEM-EREEITTKKRKLGKNPDVDTSFLPDRDRE----EEENRLREELRQEWEAKQE 192
EE++ ++EE+ +++K+ + + R++E E+E ++R++ ++ W+ ++E
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKM-------REQEDQMWEQEEKMRDQEQKMWD-QEE 565
Query: 193 KIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALE 232
+++ + E WD + KMR+ M++ +K E
Sbjct: 566 RMEKKTQEQEKKTWD-----QEEKMREEERMREREKKMRE 600
Score = 55.8 bits (133), Expect = 5e-08
Identities = 51/198 (25%), Positives = 95/198 (47%), Gaps = 32/198 (16%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEAL 80
RE+++E EQ + R EE M+ +K + E E K +QE
Sbjct: 331 REQEKELREQKELREQEEQ-MQEQEEKMWEQEEKMREQEEKMW------------RQEER 377
Query: 81 VKEREKQLAKKEQSKELQMKL-----EKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+ E+EKQ+ ++EQ Q + E+LREKE + + K+ + EE++ E+E+
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Query: 136 EAAMYEEEMEREE-ITTKKRKLGKNPDV-----------DTSFLPDRDREEEENRLREEL 183
+ EE+M+ EE I +++K+ + + + + ++E ++ RL E+
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 184 RQEWEAKQEKIKSEEIEI 201
+ WE QEK++ +E +I
Sbjct: 498 EKLWE--QEKMQEQEEKI 513
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/182 (23%), Positives = 93/182 (51%), Gaps = 7/182 (3%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+K +Q E+M++ ++++ E+ ++K E + K + + +QE
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
+ E+EK K ++ ++ EK+RE+E +E ++K+ + E+EE +E+EE
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE-K 742
Query: 139 MYEEEMEREEITTKKRKLGKNPDV--DTSFLPDRDREEEENRLREELRQEWEAKQEKIKS 196
M E+E EE+ ++ K+ + + + LP++ + E+ +E + WE ++EK++
Sbjct: 743 MQEQE---EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE-QEEKMRD 798
Query: 197 EE 198
+E
Sbjct: 799 QE 800
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/194 (24%), Positives = 93/194 (47%), Gaps = 23/194 (11%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
M++ E+ RE+ ++M++ EE +M+ +K E E K M ++
Sbjct: 585 MREEERMREREKKMRE---EEEMMREQEEKMQEQEEKMQEQEEK-----------MWEQE 630
Query: 78 EALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
E + ++ EK ++E+ E + EK+ E++R E K K+ +E+E +E+EE
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQE---EKMWEQQRLPEQKEKL--WEHEKMQEQEKMQEQEEK 685
Query: 138 AMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR----EEEENRLREELRQEWEAKQEK 193
+E+ME++ +K+ + + + +R++ EEE R +EE QE E K ++
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 194 IKSEEIEITFSYWD 207
+ E E W+
Sbjct: 746 QEEEMWEQEEKMWE 759
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/193 (22%), Positives = 90/193 (46%), Gaps = 21/193 (10%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
KK ++Q ++ ++++ EE M+ K E E K M+ ++E
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-----------MQEQEE 617
Query: 79 ALVKEREKQLAKKEQSKELQMKL----EKLREKERKKEAKRKISSLSFTLEEEEEGGEEE 134
+ ++ EK ++E+ +E + K+ EK+ E+E K ++++ L E E+ E+E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 135 EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR--EELRQEWEAK-- 190
+ E+ E+E++ K ++ K + E E ++R EE+ +E E K
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Query: 191 --QEKIKSEEIEI 201
+EK++ +E E+
Sbjct: 738 EQEEKMQEQEEEM 750
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/188 (21%), Positives = 93/188 (49%), Gaps = 14/188 (7%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K E+ + + Q++ +E + + + + E +++ + + +
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ------EKKIRKQEEKMWRQEERLRE 304
Query: 77 QEALVKEREKQLAK-----KEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGG 131
QE ++E+E+++ + +EQ KEL+ + ++LRE++ +E + ++ + E+EE
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAK 190
E+EE +EE E+ + + K D + +R E+E R+RE+ + WE +
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ-EKMWE-Q 422
Query: 191 QEKIKSEE 198
EK++ E+
Sbjct: 423 VEKMREEK 430
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/192 (21%), Positives = 90/192 (46%), Gaps = 29/192 (15%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELK--SSTVGLVTL 70
R + ++ E REQ E+M++ +E M+ +K + E E K +
Sbjct: 594 REKKMREEEEMMREQEEKMQE---QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 71 NDMKAKQEALVKEREK--QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEE-- 126
+ +Q+ L +++EK + K ++ +++Q + EK+ E+E+ ++ ++ ++ E+
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQE 186
EEE E E+ EEEM RE+ + +E+E +++E+ +
Sbjct: 711 EEESMREREKKMREEEEMMREQ--------------------EEKMQEQEEKMQEQEEEM 750
Query: 187 WEAKQEKIKSEE 198
WE +++ + EE
Sbjct: 751 WEQEEKMWEQEE 762
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/154 (27%), Positives = 84/154 (54%), Gaps = 13/154 (8%)
Query: 54 DAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREK-ERKKE 112
DA+ EL +T+ T ++K K L + + LA+ E+S E+Q+ +++L+ K ER K
Sbjct: 207 DALSLELYRNTI---TNEELKKKNAEL--QEKLPLAESEKS-EIQLNVKELKRKLERAKF 260
Query: 113 AKRKISSLSFTLE---EEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPD 169
++ + + E +EEE E+E++ EE+M R+E ++++ + + +
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320
Query: 170 RDREEEENRLRE---ELRQEWEAKQEKIKSEEIE 200
+ E+E LRE ELR++ E ++++ + +E E
Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/186 (21%), Positives = 95/186 (51%), Gaps = 15/186 (8%)
Query: 17 LMKKREKQREQ--MEQMKQRIAEENIMKSN--IDKKFSAHYDAVEAELKSSTVGLVTLND 72
+ ++ EK EQ + + K+++ E M+ + ++ ++ + E K+ T +
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
K ++E ++EREK++ +E+ + ++ + EK++E+E K + + + E+EE+ E
Sbjct: 707 EKMREEESMREREKKM--REEEEMMREQEEKMQEQEEKMQEQEEEM-----WEQEEKMWE 759
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
+EE+ + E++E + K+ + + RD+EE+ E++R ++E
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR----GQEE 815
Query: 193 KIKSEE 198
K++ +E
Sbjct: 816 KMRGQE 821
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 25/194 (12%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
R + ++ E REQ E+M++ +E M+ ++ + E E K +
Sbjct: 718 REKKMREEEEMMREQEEKMQE---QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
K + ++E+EK ++E+ ++ + K+ EK R +E K + +EE+ G+
Sbjct: 775 EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQ 834
Query: 133 EE-----EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
EE EE +EE E++ ++ K+ R++EE+ E++R++
Sbjct: 835 EEKMWGQEEKMWGQEEKMEEKMQGQEEKM-------------REQEEKMRGQEEKMREQ- 880
Query: 188 EAKQEKIKSEEIEI 201
+EK++ +E +I
Sbjct: 881 ---EEKMRGQEEKI 891
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/238 (26%), Positives = 120/238 (50%), Gaps = 22/238 (9%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ ++ EK REQ E+M ++ EE I + D+K + + + + + +
Sbjct: 355 IREQEEKIREQEEKMWRQ--EEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLRE-KERKKEAKRKISSLSFTLEEEEEGGEEEE 135
QE ++E+++++ +EQ +E+ + EK+RE +E ++ + K+ + ++EEEE +E+E
Sbjct: 411 QEKKMREQDEKI--REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 136 EAAMYEEE--MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK--- 190
E +EE E+EE T ++ KL K + R+EE+ +EE QE E K
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 191 -QEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVE 247
+EK++ +E+ + W ++ KM++ Q L++ L L + L AG E
Sbjct: 529 QEEKMREQEVRL----W-----QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/190 (24%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
+K RE++ + Q ++ +E ++ DK + E E K + + +Q
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK-----IREQEEKMWRQ 372
Query: 78 EALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
E ++E+++++ +EQ +E+ + EK+RE+E K++ K+ + E++E E+EE
Sbjct: 373 EEKIREQDEKI--QEQEEEMWRQEEKIREQEEKRQ--EKMWRQEKKMREQDEKIREQEEE 428
Query: 138 AMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR---EEEENRLREELRQEWEAK---Q 191
+EE RE + + K +V+ + ++ +EE+ + +EE QE E K Q
Sbjct: 429 MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ 488
Query: 192 EKIKSEEIEI 201
EK+ +E +I
Sbjct: 489 EKLLKQEEKI 498
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/181 (19%), Positives = 85/181 (46%), Gaps = 15/181 (8%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEAL 80
+E+ +E + I +E + + N + + VE+E + + L + + L
Sbjct: 197 KERDAPSLELYRNTITDEELKEKNAELQEKLRL--VESEKSEIQLNVKDLKRKLERAQLL 254
Query: 81 VKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMY 140
+ +++ Q+ KELQ KL+ + + E ++ ++EE+ +EE+
Sbjct: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ-----QQEEKMWRQEEKIQEQ 309
Query: 141 EEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
EE+M +E+ ++++ + + + E+E ++RE+ + W ++EKI+ +E +
Sbjct: 310 EEKMCEQELKIREQE-------EKMWRQEEKMHEQEEKIREQEDKMWR-QEEKIREQEEK 361
Query: 201 I 201
I
Sbjct: 362 I 362
Score = 46.6 bits (109), Expect = 3e-05
Identities = 56/239 (23%), Positives = 117/239 (48%), Gaps = 26/239 (10%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
KR+ +R Q+ +Q++ E + K+ + ++A+++ + + + LN + +E
Sbjct: 245 KRKLERAQLLLPQQQLQVE---ADRLGKELQSVSAKLQAQVEENELWNL-LNQQQ--EEK 298
Query: 80 LVKEREKQLAKKEQSKELQMKL----EKL-REKERKKEAKRKISSLSFTLEEEEEGGEEE 134
+ ++ EK ++E+ E ++K+ EK+ R++E+ E + KI + +EE E+
Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 135 EEAAMYEEE---MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQ 191
EE +EE + E+I + K+ + + + ++ RE+EE R + RQE + ++
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKI-QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 192 --EKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQ 248
EKI+ +E E+ W R+ K+R+ M Q ++ L + + E EQ
Sbjct: 418 QDEKIREQEEEM----W-----RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/164 (22%), Positives = 79/164 (48%), Gaps = 20/164 (12%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L + + Q E++ ++++++ EE ++K + ++ + + + +
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----------R 487
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEGGEEEE 135
QE L+K+ EK EQ +++ + EK+ E+E K +E + K+ + E+E ++E
Sbjct: 488 QEKLLKQEEKIW---EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRL 179
E M E+E+ +E+ + KLG+ ++ L RE RL
Sbjct: 545 E-KMQEQEVRLQELEERLGKLGQKAEL----LGGAGRESGSQRL 583
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/238 (26%), Positives = 120/238 (50%), Gaps = 22/238 (9%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ ++ EK REQ E+M ++ EE I + D+K + + + + + +
Sbjct: 355 IREQEEKIREQEEKMWRQ--EEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLRE-KERKKEAKRKISSLSFTLEEEEEGGEEEE 135
QE ++E+++++ +EQ +E+ + EK+RE +E ++ + K+ + ++EEEE +E+E
Sbjct: 411 QEKKMREQDEKI--REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 136 EAAMYEEE--MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK--- 190
E +EE E+EE T ++ KL K + R+EE+ +EE QE E K
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 191 -QEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVE 247
+EK++ +E+ + W ++ KM++ Q L++ L L + L AG E
Sbjct: 529 QEEKMREQEVRL----W-----QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/190 (24%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
+K RE++ + Q ++ +E ++ DK + E E K + + +Q
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEK-----IREQEEKMWRQ 372
Query: 78 EALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
E ++E+++++ +EQ +E+ + EK+RE+E K++ K+ + E++E E+EE
Sbjct: 373 EEKIREQDEKI--QEQEEEMWRQEEKIREQEEKRQ--EKMWRQEKKMREQDEKIREQEEE 428
Query: 138 AMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR---EEEENRLREELRQEWEAK---Q 191
+EE RE + + K +V+ + ++ +EE+ + +EE QE E K Q
Sbjct: 429 MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ 488
Query: 192 EKIKSEEIEI 201
EK+ +E +I
Sbjct: 489 EKLLKQEEKI 498
Score = 46.6 bits (109), Expect = 3e-05
Identities = 56/239 (23%), Positives = 117/239 (48%), Gaps = 26/239 (10%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
KR+ +R Q+ +Q++ E + K+ + ++A+++ + + + LN + +E
Sbjct: 245 KRKLERAQLLLPQQQLQVE---ADRLGKELQSVSAKLQAQVEENELWNL-LNQQQ--EEK 298
Query: 80 LVKEREKQLAKKEQSKELQMKL----EKL-REKERKKEAKRKISSLSFTLEEEEEGGEEE 134
+ ++ EK ++E+ E ++K+ EK+ R++E+ E + KI + +EE E+
Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 135 EEAAMYEEE---MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQ 191
EE +EE + E+I + K+ + + + ++ RE+EE R + RQE + ++
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKI-QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 192 --EKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQ 248
EKI+ +E E+ W R+ K+R+ M Q ++ L + + E EQ
Sbjct: 418 QDEKIREQEEEM----W-----RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Score = 45.8 bits (107), Expect = 5e-05
Identities = 36/181 (19%), Positives = 85/181 (46%), Gaps = 15/181 (8%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEAL 80
+E+ +E + I +E + + N + + VE+E + + L + + L
Sbjct: 197 KERDALSLELYRNTITDEELKEKNAELQEKLRL--VESEKSEIQLNVKDLKRKLERAQLL 254
Query: 81 VKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMY 140
+ +++ Q+ KELQ KL+ + + E ++ ++EE+ +EE+
Sbjct: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ-----QQEEKMWRQEEKIQEQ 309
Query: 141 EEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
EE+M +E+ ++++ + + + E+E ++RE+ + W ++EKI+ +E +
Sbjct: 310 EEKMCEQELKIREQE-------EKMWRQEEKMHEQEEKIREQEDKMWR-QEEKIREQEEK 361
Query: 201 I 201
I
Sbjct: 362 I 362
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/164 (22%), Positives = 79/164 (48%), Gaps = 20/164 (12%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L + + Q E++ ++++++ EE ++K + ++ + + + +
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----------R 487
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEGGEEEE 135
QE L+K+ EK EQ +++ + EK+ E+E K +E + K+ + E+E ++E
Sbjct: 488 QEKLLKQEEKIW---EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRL 179
E M E+E+ +E+ + KLG+ ++ L RE RL
Sbjct: 545 E-KMQEQEVRLQELEERLGKLGQKAEL----LGGAGRESGSQRL 583
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 60.5 bits (145), Expect = 2e-09
Identities = 59/250 (23%), Positives = 122/250 (48%), Gaps = 27/250 (10%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAE--LKSSTVGLVTLNDMKA 75
M ++EK REQ +QM + +E M+ K + E + L+ + M
Sbjct: 475 MWRQEKMREQEDQMWE---QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
++E + +E++ Q EQ K+ + EK+RE+ER +E ++K+ + E+EE +E+E
Sbjct: 532 QEEKMREEKKTQ----EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 136 EAAMYEEEM----------EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ 185
E +EE + E++ ++ K+ + + D + E+E +++E+ +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 186 EWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAG 245
WE ++EK++ +E ++ G KMR+ ++ +Q E +R+ ++R G
Sbjct: 648 MWE-QEEKMREQEEKMREQEEKMQGQEE--KMRE---QEEKMQGQEEKMREQEEKMR--G 699
Query: 246 VEQLMYIKED 255
E+ M+ +E+
Sbjct: 700 QEEKMWGQEE 709
Score = 57.8 bits (138), Expect = 1e-08
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 28/186 (15%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEAL 80
RE+++E EQ K R EE M+ +K + E E K +QE
Sbjct: 293 REQEKELREQKKLREQEEQ-MQEQEEKMWEQEEKMREQEEKMW------------RQEER 339
Query: 81 VKEREKQLAKKEQSKELQMKL-----EKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+ E+EKQ+ ++EQ Q + E+LREKE + + K + E+EE +EEE
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-------MWEQEEKMQEEE 392
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
E++M EE T ++++ K + + ++E ++ RL E+ + WE QEK++
Sbjct: 393 RIREREKKMREEEETMREQE-EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE--QEKMQ 449
Query: 196 SEEIEI 201
+E +I
Sbjct: 450 EQEEKI 455
Score = 56.6 bits (135), Expect = 3e-08
Identities = 55/263 (20%), Positives = 124/263 (47%), Gaps = 27/263 (10%)
Query: 17 LMKKREKQREQMEQM-----------KQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTV 65
+ ++ EK REQ E+M KQ +E M+ ++ + E E +
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Query: 66 GLVTLNDMKAKQEALVKEREKQLAK-----KEQSKELQMKLEKLREKERKKEAKRKISSL 120
+ + K ++E ++EREK++ + +EQ +++Q + E + E+E K+ ++++
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 121 SFTLEEEEEGGEEEEEAAMYEEEM-EREEITTKKRKLGKNPDV----DTSFLPDRDREEE 175
L E+E+ E+EE+ EE++ ++EE+ +++K+ + + D + + ++
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 176 ENRLREELRQEWEAKQE-KIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEIL 234
E ++ ++ + WE + + K E + W ++ KMR+ Q+ +K +
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMW-----QQEEKMREEKKTQEQEKKTWDQE 553
Query: 235 RKDFSELRSAGVEQLMYIKEDLI 257
K E R E+ M +E+++
Sbjct: 554 EKMREEERMREREKKMREEEEMM 576
Score = 53.1 bits (126), Expect = 3e-07
Identities = 37/124 (29%), Positives = 71/124 (57%), Gaps = 5/124 (4%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+QE ++ +EK+L +EQ KEL+ + ++LRE+++ +E + ++ + E+EE E+E
Sbjct: 273 EQEEKMRRQEKRL--REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAKQEKI 194
E +EE E+ + + K D + +R E+E R+RE+ + WE ++EK+
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ-EKMWE-QEEKM 388
Query: 195 KSEE 198
+ EE
Sbjct: 389 QEEE 392
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/193 (24%), Positives = 97/193 (50%), Gaps = 18/193 (9%)
Query: 17 LMKKREKQREQ--MEQMKQRIAEENIMKSNIDKKFSAHYDAVEAE-LKSSTVGLVTLNDM 73
L +K E+ REQ M Q ++++ EE + K + E E ++ + +M
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
Query: 74 KAKQEALVKEREKQLAKKE-----QSKELQMKLEKLREKERK---KEAKRKISSLSFTLE 125
+QE ++E+E+++ ++E Q +++Q + EK+ E+E K +E + K+ +
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635
Query: 126 EEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ 185
E+EE +E+EE +EE RE+ + + K + R++EE+ E++R+
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM---REQEEKMQGQEEKMRE 692
Query: 186 EWEAKQEKIKSEE 198
+ +EK++ +E
Sbjct: 693 Q----EEKMRGQE 701
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 9/190 (4%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK-- 76
+K ++Q E++ + +++I ++ M K + + + + + D + K
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW--RQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 77 -QEALVKEREKQLAKKEQSKELQMKL----EKLREKERKKEAKRKISSLSFTLEEEEEGG 131
QE + E++++L +KE+ Q K+ EK+RE+++ +E ++K + EEE
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQ 191
E E++ EE M +E ++++ + + + +E+E ++ E+ + WE ++
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 192 EKIKSEEIEI 201
E E+ E+
Sbjct: 624 EDKMQEQEEM 633
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/182 (20%), Positives = 91/182 (50%), Gaps = 22/182 (12%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K E+ + + Q++ +E + + E EL+ + + +
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQ-------------EEELREQEKKIRKQEEKMWR 259
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
QE ++E+E ++ +EQ ++++ + ++LRE+E++ + K L E+EE +E+EE
Sbjct: 260 QEERLREQEGKM--REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKS 196
+EE RE+ + K+ + + + ++ E+E ++R++ + WE + E+++
Sbjct: 318 KMWEQEEKMREQ----EEKMWRQE--ERLWEQEKQMREQEQKMRDQEERMWE-QDERLRE 370
Query: 197 EE 198
+E
Sbjct: 371 KE 372
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/164 (23%), Positives = 82/164 (50%), Gaps = 13/164 (7%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV-EAELKSSTVGLVTLNDMKA 75
+ ++ EK +EQ E+M ++ EE + + + K + + E E K + +
Sbjct: 597 MWEQEEKMQEQEEKMWEQ--EEKMWEQEEEDKMQEQEEMMWEQEEK-----MQEQEEKMW 649
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERK---KEAKRKISSLSFTLEEEEEGGE 132
+QE ++E+E+++ +EQ +++Q + EK+RE+E K +E K + +EE+ G+
Sbjct: 650 EQEEKMREQEEKM--REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEE 176
EE+ E+ +EE+ K+ ++ + LP+ + E
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 42.4 bits (98), Expect = 6e-04
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 28/160 (17%)
Query: 54 DAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEA 113
DA+ EL +T+ T ++K K L + + +LA+ E+S E+Q+ + KE
Sbjct: 169 DALSLELYRNTI---TNEELKKKNAEL--QEKLRLAESEKS-EIQLNV---------KEL 213
Query: 114 KRKISSLSFTL-------------EEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNP 160
KRK+ F L +EEE E+E++ EE+M R+E ++++
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 161 DVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
+ ++ E+E LRE+ ++ E K+ + + E+++
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ 313
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 60.1 bits (144), Expect = 3e-09
Identities = 48/198 (24%), Positives = 98/198 (49%), Gaps = 17/198 (8%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV----EAELKSSTVGLVTLNDM 73
M +EK+R+++E ++++ E + + +++ + V E L+ + M
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 74 KAKQEALVKEREKQLAKK-EQSKELQMKLEKLREKERKK-----EAKRKISS----LSFT 123
K +++ ++++ Q+ +K E++KE ++ EK ++K K EA+RK L +
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
Query: 124 LEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREEL 183
+EEEE +E EEE ER + ++L + + + R++E E RE+
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 184 RQEWE---AKQEKIKSEE 198
R+E E A+QE+ + +E
Sbjct: 708 RREQERQLAEQERRREQE 725
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/296 (22%), Positives = 136/296 (45%), Gaps = 31/296 (10%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
R +++ RE+ + E+ K++ I++KF+ + + K+ L +
Sbjct: 573 RLRKVLQARERVEQMKEEKKKQ----------IEQKFA------QIDEKTEKAKEERLAE 616
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
KAK++A K+ E+ A+++Q +E + +LR ++++E +R L EEE+E
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEAR----RLRWLQQEEEERRHQELLQKKKEEEQERLR 672
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAKQ 191
+ EA E+ E+E ++R+ + +++R E+E +L E E R+E E Q
Sbjct: 673 KAAEAKRLAEQREQERREQERREQERREQERR----EQERREQERQLAEQERRREQERLQ 728
Query: 192 EKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQLMY 251
+ + +E E R + +K Q+ ++ L+ ++ +AG + +
Sbjct: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ-EEQEKKAKEAAGASKALN 787
Query: 252 IKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDESHAGKVV 307
+ D+ P S+ +T ++ P N D + + L SD + + DE+H K +
Sbjct: 788 VTVDVQSPACTSYQ---MTPQGHRAPPKINPDNY-GMDLNSDDSTD-DEAHPRKPI 838
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 59.7 bits (143), Expect = 4e-09
Identities = 45/190 (23%), Positives = 99/190 (52%), Gaps = 9/190 (4%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K +Q + EQ ++R EE I + ++ A E +++ + +M +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 77 QEALVKEREKQLAKKE-----QSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEG 130
QE + E+E+++ ++E Q ++++ + EK+RE+E+K +E + KI ++E+EE
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE- 467
Query: 131 GEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDRE--EEENRLREELRQEWE 188
E+E M E+E + +E K R+ + + +++ + E+E ++E+ + WE
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Query: 189 AKQEKIKSEE 198
+++ + EE
Sbjct: 528 QEEKMCEQEE 537
Score = 55.8 bits (133), Expect = 5e-08
Identities = 54/237 (22%), Positives = 104/237 (43%), Gaps = 21/237 (8%)
Query: 8 ASEAGRAMHLMKKREKQRE--QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTV 65
A++ +A +++ K+R+ +E + I +E + + N K VE+E +
Sbjct: 173 ATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA--KLQEKLQLVESEKSEIQL 230
Query: 66 GLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLR---------------EKERK 110
+ L + + L+ +++ Q KELQ KL+ ++E+
Sbjct: 231 NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 290
Query: 111 KEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLP 168
+ KI ++E+EE E+EE +EEM E+EE ++ ++ + L
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 350
Query: 169 DRDREEEENRLREELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQ 225
++ E+E+ R +EE RQE E +E+ K +E E + + K+R+ M Q
Sbjct: 351 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Score = 54.7 bits (130), Expect = 1e-07
Identities = 54/213 (25%), Positives = 104/213 (48%), Gaps = 19/213 (8%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIA----EENIMKSNIDKKFSAHYDAVEAELKSSTVGLV 68
R + ++ EK REQ E+M+++ +E M+ + + E E K +
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 359
Query: 69 TLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
+ K ++E ++E+EK ++EQ ++ + EK+RE+E K + ++ ++E+E
Sbjct: 360 REQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIREQEEM------MQEQE 410
Query: 129 EGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWE 188
E E+EE M+E+E E +E K R+ + + + +EE+ R +EE+ QE E
Sbjct: 411 EKMGEQEE-KMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE---QEEKIREQEEMMQEQE 466
Query: 189 AK--QEKIKSEEIEITFSYWDGSGHRRTVKMRK 219
K +++ K E E + R+ K+R+
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Score = 50.4 bits (119), Expect = 2e-06
Identities = 39/186 (20%), Positives = 94/186 (50%), Gaps = 10/186 (5%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKAK 76
K +Q E++ + +++I E+ M ++K + + E E++ + + +
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKK-EAKRKISSLSFTLEEEEEGGEEEE 135
QE ++E+E+++ +EQ + +Q + EK+ E+E K E + K+ + +EE E+E
Sbjct: 444 QEKKIREQEEKI--REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAKQEKI 194
+ +EE RE+ + + K + + ++ +E+E ++R RQE + +++++
Sbjct: 502 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---RQEEKMREQEV 558
Query: 195 KSEEIE 200
+ + E
Sbjct: 559 RLRQQE 564
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/181 (24%), Positives = 91/181 (50%), Gaps = 28/181 (15%)
Query: 22 EKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKAKQE 78
++Q E+M + ++++ E+ ++K + + E +++ + +M +QE
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 79 ALVKEREKQLAKKE-----QSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEGGE 132
+ E+E ++ ++E Q ++++ + EK+RE+E+K +E + KI ++E+EE
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAKQ 191
E+EE M E+E + +E K R R+EE+ R +E LRQ+ E Q
Sbjct: 527 EQEE-KMCEQEEKMQEQEEKMR-----------------RQEEKMREQEVRLRQQEEKMQ 568
Query: 192 E 192
E
Sbjct: 569 E 569
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/149 (22%), Positives = 82/149 (55%), Gaps = 14/149 (9%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ ++ E+ +EQ E+M+++ EE I + +KK + + + + + + + K
Sbjct: 420 MWEQEEEMQEQEEKMRRQ--EEKIREQ--EKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Query: 77 ---QEALVKEREKQLAK-----KEQSKELQMKLEKLREKER--KKEAKRKISSLSFTLEE 126
QEA ++E+E+++ + +EQ K+++ + EK+RE+E +++ ++ E+
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRK 155
EE+ E+EE+ EE+M +E+ ++++
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 58.9 bits (141), Expect = 6e-09
Identities = 72/306 (23%), Positives = 133/306 (43%), Gaps = 37/306 (12%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L K+ +K E + +K E N N++ D + A++KS+ ++T ++ +
Sbjct: 846 LKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISI----DTLMAKIKST---MMTQEQIQKE 898
Query: 77 QEALVKEREKQLA---KKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
+ALVK E+ L+ KK+Q +E +L +++E+ K+ +R+ EEEE +
Sbjct: 899 YDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
E EA +EE ER++ ++++ +V+ ++ E ++ + E+ R++ E
Sbjct: 959 EMEAKRKQEEEERKKREDDEKRI--QAEVEAQLARQKEEESQQQAVLEQERRDRELALRI 1016
Query: 194 IKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSEL---RSAGVEQLM 250
+SE I+ RR R T +Q ++ E L + + L +AG +
Sbjct: 1017 AQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTK--- 1073
Query: 251 YIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDESHAGKVVLRS 310
K DL + D I T D+ LL+ ++E H V +
Sbjct: 1074 --KYDLSKWKYAELRDTINTSC--------------DIELLAAC---REEFHRRLKVYHA 1114
Query: 311 WYEKNK 316
W KNK
Sbjct: 1115 WKSKNK 1120
Score = 32.0 bits (71), Expect = 0.81
Identities = 31/146 (21%), Positives = 63/146 (43%), Gaps = 36/146 (24%)
Query: 3 QYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKS 62
Q + A R M+K K+RE+ E+ +++ EE MK
Sbjct: 918 QQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL------------------- 958
Query: 63 STVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSF 122
+M+AK++ +ER+K +++ K +Q ++E +++++E++++
Sbjct: 959 ---------EMEAKRKQEEEERKK---REDDEKRIQAEVEAQLARQKEEESQQQA----- 1001
Query: 123 TLEEEEEGGEEEEEAAMYEEEMEREE 148
LE+E E A E E+ +E
Sbjct: 1002 VLEQERRDRELALRIAQSEAELISDE 1027
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 58.2 bits (139), Expect = 1e-08
Identities = 48/191 (25%), Positives = 86/191 (45%), Gaps = 15/191 (7%)
Query: 10 EAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVT 69
E R + K+ +K+RE + ++R E+ + ++K + E K
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99
Query: 70 LNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEE 129
K +E KE+ K+ KKE+ + + E+ R++ERK+E +++ E+E E
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159
Query: 130 GGE--EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
E + E + E+E ER+E K+RK R+R +E + E ++
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERK-------------KRERNRKERKKERERKERR 206
Query: 188 EAKQEKIKSEE 198
E K+E+ K EE
Sbjct: 207 ERKKERKKKEE 217
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/183 (26%), Positives = 87/183 (47%), Gaps = 16/183 (8%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
K+R+++R + E+ +R EE K +K + + E K + +
Sbjct: 75 KERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE-------KKERGRTS 127
Query: 79 ALVKERE-KQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
KERE K+ K+E+ KE + K E+ REKER+++ ++K E ++ G +EEE
Sbjct: 128 KEGKERERKEERKREERKERERKKEE-REKERERKERKK-------RERKQVGEKEEERK 179
Query: 138 AMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSE 197
+E ++ E K+RK + +R ++EE + R++ RQ ++E+ K E
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
Query: 198 EIE 200
E
Sbjct: 240 RKE 242
Score = 48.9 bits (115), Expect = 6e-06
Identities = 36/130 (27%), Positives = 66/130 (50%), Gaps = 20/130 (15%)
Query: 81 VKEREKQL-AKKEQSKELQMKLEK-LREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
++ERE+++ +KE KE + + +K RE+E++K + K E + E G++E++
Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREK--------ERKRERGKKEKKGE 89
Query: 139 MYEEEMER----------EEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWE 188
+EE ER E +KRK + + + ++RE +E R REE ++
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 189 AKQEKIKSEE 198
K+E+ K E
Sbjct: 150 KKEEREKERE 159
Score = 48.9 bits (115), Expect = 6e-06
Identities = 39/164 (23%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
++REK+ ++ E+ ++R +E + K+ E + + + + K+E
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER-------KERERKKE 152
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
KERE++ KK + K++ K E+ +EKERK+ KR+ +E +E E
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRE--------RNRKERKKERERKE 204
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE 182
E + ER++ ++RK + D T++ +++R + E + R++
Sbjct: 205 RRERKKERKK--KEERKKERQKDRQTNW-REKERGKRERKERKK 245
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 18/135 (13%)
Query: 5 KGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSST 64
+G S+ G+ +K E++RE+ ++ +++ E + ++K E E
Sbjct: 123 RGRTSKEGKERE--RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE----- 175
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRK---ISSLS 121
+ K K+ K+RE+ +KE+ KE + K + R+KERKK+ +RK
Sbjct: 176 ------EERKEKERKERKKRERN--RKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
Query: 122 FTLEEEEEGGEEEEE 136
E+E G E +E
Sbjct: 228 TNWREKERGKRERKE 242
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 12/98 (12%)
Query: 103 KLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDV 162
++RE+ER+ E +++ E E + E E E E ER+ KK K G+
Sbjct: 37 EIREREREIETRKEGKK---ERESERKKERREREKRKREREKERKRERGKKEKKGER--- 90
Query: 163 DTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
++ E + R RE+ +E E K+++ K E+ E
Sbjct: 91 ------KKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/194 (24%), Positives = 96/194 (49%), Gaps = 17/194 (8%)
Query: 22 EKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV----EAELKSSTVGLVTLNDMKAKQ 77
EK+R+++E ++++ E + + +++ + V E L+ + MK ++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 78 EALVKEREKQLAKK-EQSKELQMKLEKLREKERKK-----EAKRKISS----LSFTLEEE 127
+ ++++ Q+ +K E++KE ++ EK ++K K EA+RK L + +EE
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 655
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
EE +E EEE ER + ++L + + + R++E E RE+ R+E
Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 715
Query: 188 E---AKQEKIKSEE 198
E A+QE+ + +E
Sbjct: 716 ERQLAEQERRREQE 729
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/296 (22%), Positives = 136/296 (45%), Gaps = 31/296 (10%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
R +++ RE+ + E+ K++ I++KF+ + + K+ L +
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQ----------IEQKFA------QIDEKTEKAKEERLAE 620
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
KAK++A K+ E+ A+++Q +E + +LR ++++E +R L EEE+E
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEAR----RLRWLQQEEEERRHQELLQKKKEEEQERLR 676
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAKQ 191
+ EA E+ E+E ++R+ + +++R E+E +L E E R+E E Q
Sbjct: 677 KAAEAKRLAEQREQERREQERREQERREQERR----EQERREQERQLAEQERRREQERLQ 732
Query: 192 EKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQLMY 251
+ + +E E R + +K Q+ ++ L+ ++ +AG + +
Sbjct: 733 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ-EEQEKKAKEAAGASKALN 791
Query: 252 IKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDESHAGKVV 307
+ D+ P S+ +T ++ P N D + + L SD + + DE+H K +
Sbjct: 792 VTVDVQSPACTSYQ---MTPQGHRAPPKINPDNY-GMDLNSDDSTD-DEAHPRKPI 842
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 57.8 bits (138), Expect = 1e-08
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 9/191 (4%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
K +Q E++ + +++I E+ ++K E E + + + +QE
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 80 LVKEREKQLAKKEQSKELQMKL----EKLREKERK-KEAKRKISSLSFTLEEEEEGGEEE 134
+ +++EK ++E+ ++ + K+ EK+RE+E K +E + K+ + E+EE EE
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
Query: 135 EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK---- 190
E+ E+ E E+ ++ K+ + + R+EE+ R +EE RQE E K
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 191 QEKIKSEEIEI 201
+EKI+ +E +I
Sbjct: 611 EEKIREQEEKI 621
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/191 (25%), Positives = 94/191 (49%), Gaps = 15/191 (7%)
Query: 17 LMKKREKQREQMEQMKQ--------RIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLV 68
+ ++ EK REQ E ++ +I EE + DK + E E K
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 69 TLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
+ +QE K +++ +EQ +++Q + EK+RE+E K + ++ T E+EE
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM-----TQEQEE 647
Query: 129 EGGEEEEEAAMYEEEM-EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
+ GE+EE+ EE+M E+EE ++ + + + ++ RE+EE ++E+ + W
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE-MMQEQEEKMW 706
Query: 188 EAKQEKIKSEE 198
E +++ + EE
Sbjct: 707 EQEEKMCEQEE 717
Score = 56.6 bits (135), Expect = 3e-08
Identities = 47/191 (24%), Positives = 89/191 (46%), Gaps = 6/191 (3%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K +Q + EQ ++R EE I + ++ A E +++ + +
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 77 QEALVKEREK--QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEE 134
QE + E+EK + K+++ +E+ + EK+ E+E K K+ + ++EE +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 135 EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK---- 190
EE +EE RE+ R+ K + + + + E+E EE RQE E K
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 191 QEKIKSEEIEI 201
+EKI+ +E ++
Sbjct: 576 EEKIREQEEKV 586
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/246 (24%), Positives = 117/246 (47%), Gaps = 33/246 (13%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ ++ EK REQ E+M++ +E +M +K E E K + M K
Sbjct: 323 IREQEEKIREQEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM----MWEK 375
Query: 77 QEALVKEREKQLAKKEQSKELQMKL---EKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
+E + ++ E K+E+ +EL+ K+ EK+RE+E K++ + KI E+ +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI---------REQEKRQ 426
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
E+EA M+ +E + E K R+ K + ++++ EE + R+E + W +++
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK-RQEQEEMWRQEEKI 485
Query: 194 IKSEEIEITFSYW--DGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQLMY 251
+ EEI W H + K+RK ++ + + E +R+ ++R E+ M+
Sbjct: 486 HEQEEI------WRQKEKMHEQEEKIRK---QEEKVWRQEEKIREQEEKIREQ--EEKMW 534
Query: 252 IKEDLI 257
+E+ I
Sbjct: 535 RQEEKI 540
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/187 (25%), Positives = 100/187 (53%), Gaps = 20/187 (10%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
++ EK REQ E+++++ EE + + ++K + E K + + + +QE
Sbjct: 514 RQEEKIREQEEKIREQ--EEKMWRQ--EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKK-EAKRKISSLSFTLEEEEEGGEEEEEA 137
+ +E+++ +EQ +++ + EK+RE+E K+ E + K+ + E+EE +E+EE
Sbjct: 570 DKMWRQEEKI--REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Query: 138 AMYEEE--MEREEIT-TKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKI 194
+EE E+EE+T ++ K+G+ + E+E +++E+ W ++EKI
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQ---------EEKMCEQEEKMQEQEETMWR-QEEKI 677
Query: 195 KSEEIEI 201
+ +E +I
Sbjct: 678 REQEKKI 684
Score = 51.2 bits (121), Expect = 1e-06
Identities = 44/183 (24%), Positives = 88/183 (48%), Gaps = 40/183 (21%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+KR++Q E+M + +++I E+ ++K + + + +M +QE
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ-----------EEMTQEQE 646
Query: 79 ALVKEREKQLAKKEQSKELQMKL-----EKLREKERK-KEAKRKISSLSFTLEEEEEG-G 131
+ E+E+++ ++E+ + Q + EK+RE+E+K +E + KI ++E+EE
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE--LRQEWEA 189
E+EE+ EE+M+ +E ++ R +EE +E LRQ+ E
Sbjct: 707 EQEEKMCEQEEKMQEQE--------------------EKMRRQEEKMWEQEVRLRQQEEK 746
Query: 190 KQE 192
QE
Sbjct: 747 MQE 749
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/191 (26%), Positives = 99/191 (51%), Gaps = 19/191 (9%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
KR+ +R ++ +Q++ E ++ K+ + V A+L++ N + +QE
Sbjct: 248 KRKLERAKLLLPQQQLQAE---ADHLGKELQS----VSAKLQAQVEENELWNRLNQQQEE 300
Query: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERK----KEAKRKISSLSFTLEE----EEEGG 131
+ +E+++ +E +++Q + EK+RE+E K +E R+ + + EE +EE
Sbjct: 301 KMWRQEEKI--QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 132 EEEEEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEA 189
E+EE +EEM E+EE ++ ++ + L ++ E+E+ R +EE RQE E
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 190 KQEKIKSEEIE 200
+E+ K +E E
Sbjct: 419 IREQEKRQEQE 429
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/193 (19%), Positives = 90/193 (46%), Gaps = 10/193 (5%)
Query: 8 ASEAGRAMHLMKKREKQRE--QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTV 65
A++ +A +++ K+R+ +E + I +E + + N K VE+E +
Sbjct: 185 ATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA--KLQEKLQLVESEKSEIQL 242
Query: 66 GLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLE 125
+ L + + L+ +++ Q KELQ KL+ + + E +++ +
Sbjct: 243 NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ-----Q 297
Query: 126 EEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ 185
+EE+ +EE+ +EE+++ +E ++++ + + E+E ++R +
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 186 EWEAKQEKIKSEE 198
WE K+EK++ +E
Sbjct: 358 MWE-KEEKMRRQE 369
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/182 (24%), Positives = 97/182 (53%), Gaps = 12/182 (6%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
+++ EK++EQ E +Q EE I + + E +++ + + Q
Sbjct: 513 IREEEKRQEQEEMWRQ---EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 78 EALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
E ++E+E+++ ++E+ +++ + EK+RE+E K + ++ T E+EE+ GE+EE+
Sbjct: 570 EEKIREQEEKVWRQEE--KIREQEEKIREQEEKIREQEEM-----TQEQEEKMGEQEEKM 622
Query: 138 AMYEEEM-EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKS 196
EE+M E+EE ++ + + + ++ RE+EE ++E+ + WE +++ +
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE-MMQEQEEKMWEQEEKMCEQ 681
Query: 197 EE 198
EE
Sbjct: 682 EE 683
Score = 54.7 bits (130), Expect = 1e-07
Identities = 49/190 (25%), Positives = 94/190 (49%), Gaps = 14/190 (7%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K +Q + EQ ++R EE I + ++ A E +++ + + +
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Query: 77 QEALVKEREK--QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEE 134
QE + E+EK + K+++ +E+ + EK+RE+E K KI E+EE+ ++E
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH------EQEEKIRKQE 556
Query: 135 EEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK-- 190
E+ EE+M + E+I ++ K+ + + +EE+ R +EE+ QE E K
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 191 --QEKIKSEE 198
+EK+ +E
Sbjct: 617 EQEEKMCEQE 626
Score = 54.7 bits (130), Expect = 1e-07
Identities = 46/196 (23%), Positives = 91/196 (46%), Gaps = 20/196 (10%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+KR++Q +M + +++I E+ ++K + + + K + +QE
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREK------------ERKKEAKRKISSLSFTLEE 126
++E+E+ +KE+ E + K+ K EK E+ +E + K+ + E
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQE 186
+EE E+EE +EEM +E+ + K+G+ + +EE+ R +EE +E
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQ----EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 187 WEAK----QEKIKSEE 198
E K +EKI+ +E
Sbjct: 646 QEKKIREQEEKIREQE 661
Score = 53.1 bits (126), Expect = 3e-07
Identities = 53/197 (26%), Positives = 99/197 (50%), Gaps = 13/197 (6%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFS-AHYDAVEAELKSSTVGL-VTLNDMK 74
L +K K +E+++ ++ +E + + +K A + +L++ L L +
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 339
Query: 75 AKQEALVKERE------KQLAKK--EQSKELQMKLEKLREKERK-KEAKRKISSLSFTLE 125
AK +A V+E E +Q +K Q +++Q EK++E+E K +E + KI +
Sbjct: 340 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399
Query: 126 EEEEGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREEL 183
+EE E+EE +EEM E+EE ++ ++ + L ++ E+E+ R +EE
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 184 RQEWEAKQEKIKSEEIE 200
RQE E +E+ K +E E
Sbjct: 460 RQEEEKIREQEKRQEQE 476
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/187 (22%), Positives = 95/187 (50%), Gaps = 17/187 (9%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+K ++Q E++ + +++I E+ + + ++ ++ E + + M K+E
Sbjct: 375 EKIQEQEEKIREQEEKIREQ---EEKMRRQEEMMWEKEEKMRRQEEM-------MWEKEE 424
Query: 79 ALVKEREKQLAKKEQSKELQMKL---EKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+ ++ E K+E+ +EL+ K+ EK+RE+E K++ + KI E+E + +EE
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 136 EAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
+ EE++ + E++ ++ K+ + + R +EE R E++R++ E ++K
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 194 IKSEEIE 200
K E E
Sbjct: 543 EKIHEQE 549
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/183 (24%), Positives = 89/183 (48%), Gaps = 33/183 (18%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+K +Q E+M +++I E+ ++K E +++ + +M +QE
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ----EEKIREQEEKIREQEEMTQEQE 612
Query: 79 ALVKEREKQLAKKE-----QSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEG-G 131
+ E+E+++ ++E Q ++++ + EK+RE+E+K +E + KI ++E+EE
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE--LRQEWEA 189
E+EE+ EE+M+ +E ++ R +EE +E LRQ+ E
Sbjct: 673 EQEEKMCEQEEKMQEQE--------------------EKMRRQEEKMWEQEVRLRQQEEK 712
Query: 190 KQE 192
QE
Sbjct: 713 MQE 715
Score = 48.5 bits (114), Expect = 8e-06
Identities = 41/138 (29%), Positives = 73/138 (52%), Gaps = 21/138 (15%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKK--------EAKRKISSLSFTLEEE 127
+QE ++E E+++ +EQ ++++ + EK+RE+E K E + K+ + E+
Sbjct: 365 RQEEKIQEWEEKI--QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
EE +EE M+E+E + E+ K + K + + R+EEE +E RQE
Sbjct: 423 EEKMRRQEEM-MWEKEEKIRELEEKMHEQEKIRE------QEEKRQEEEKIREQEKRQEQ 475
Query: 188 EAK----QEKIKSEEIEI 201
EAK +EKI+ +E +I
Sbjct: 476 EAKMWRQEEKIREQEEKI 493
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/189 (21%), Positives = 91/189 (48%), Gaps = 9/189 (4%)
Query: 17 LMKKREKQREQME--QMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLN 71
+ ++ EK REQ E + K++I E+ ++K + + E +++ +
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Query: 72 DMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKK-EAKRKISSLSFTLEEEEEG 130
+ +QE ++E+E+++ +EQ + Q + EK+ E+E K E + K+ + +EE
Sbjct: 585 EKIREQEEKIREQEEKI--REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 131 GEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEA 189
E+E+ +EE RE+ + + K + + ++ +E+E ++R + + WE
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 190 KQEKIKSEE 198
+ + EE
Sbjct: 703 EVRLRQQEE 711
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/172 (20%), Positives = 78/172 (45%), Gaps = 13/172 (7%)
Query: 27 QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREK 86
++EQ +A + ++ + DA+ EL +T+ D + K++ + +
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI-----TDEELKEKNAKLQEKL 291
Query: 87 QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMER 146
QL + E+S E+Q+ +++L+ K + AK + E + G E + +A + ++E
Sbjct: 292 QLVESEKS-EIQLNVKELKRKLER--AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 348
Query: 147 EEITTK-----KRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
E+ + + K+ + + + +EE+ R +EE +E E K +
Sbjct: 349 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Score = 35.4 bits (80), Expect = 0.073
Identities = 23/116 (19%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 22 EKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALV 81
++Q E+M + ++++ E+ ++K + + + K + + +QE ++
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK----IREQEEKIREQEEMM 664
Query: 82 KEREKQLAKKEQSK-ELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
+E+E+++ ++E+ E + K+++ EK R++E K+ L ++EE +E +E
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQE 718
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/200 (23%), Positives = 102/200 (51%), Gaps = 12/200 (6%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIA-EENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLN 71
R L ++++ +REQ + +Q++ E+ + + +++ ++ E + +
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 456
Query: 72 DMKAKQEAL--VKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEE 129
+K ++E +ER KQ K++Q +E + + KL E+ER+++ +R+ L EE E
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 130 ---GGEEEEEAAMY----EEEMEREEITTKKRKLGKNPD--VDTSFLPDRDREEEENRLR 180
+EEEE E+++ RE+ +++ L + + ++ R + E+E R
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 181 EELRQEWEAKQEKIKSEEIE 200
+ L++E E +Q+++K E+ E
Sbjct: 577 QLLKREEERRQQRLKREQEE 596
Score = 56.6 bits (135), Expect = 3e-08
Identities = 43/185 (23%), Positives = 96/185 (51%), Gaps = 8/185 (4%)
Query: 19 KKREKQREQMEQMKQRI-AEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
++R K++E+ E+++QR+ +E+ + + +++ E L+ + + ++
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 78 EALVK---EREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE-- 132
+ L+K ER +Q K+EQ + L+ +L++ E ER ++ +R+ L EEE +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKR-EEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 133 -EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQ 191
EE+ ++++ RE+ ++++L + + + + EEE R +E +E E +
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 192 EKIKS 196
E+IKS
Sbjct: 695 ERIKS 699
Score = 56.6 bits (135), Expect = 3e-08
Identities = 49/208 (23%), Positives = 96/208 (46%), Gaps = 20/208 (9%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEEN------IMKSNIDKKFSA----HYDAVEAELKS 62
R L+K+ E++R + E+ +QR+ E ++K +++ + +E LK
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 63 STVGLVTLND---MKAKQEALVKEREKQLAKKEQSKEL-QMKLEKLREKERKKEAKRKIS 118
V + + + K+E +ER +QL K E+ +E Q +L + +++ R++ KR+
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 119 SLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKR------KLGKNPDVDTSFLPDRDR 172
+ E EE E + EEE E+ K R +L D S + R R
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 173 EEEENRLREELRQEWEAKQEKIKSEEIE 200
++E R R+E ++ ++ +++ +E E
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEE 752
Score = 55.8 bits (133), Expect = 5e-08
Identities = 41/197 (20%), Positives = 99/197 (50%), Gaps = 22/197 (11%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L ++R+++ + EQ+ Q E+ + + D+KF + + + + + +
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
++ L + E+QL ++E+ ++ + + ++LR +ER+++ L+EE++ +E E
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK----------FLQEEQQLRRQELE 1722
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDV-----DTSFLPDRD-----REEEENRLREELRQE 186
EEE R+E T++ +L + + P+R+ R+E + + REE +
Sbjct: 1723 RKFREEEQLRQE--TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 187 WEAKQEKIKSEEIEITF 203
E ++++++S+E + F
Sbjct: 1781 QEREEQQLRSQESDRKF 1797
Score = 55.1 bits (131), Expect = 9e-08
Identities = 51/207 (24%), Positives = 93/207 (44%), Gaps = 25/207 (12%)
Query: 3 QYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKS 62
Q K E R L + E++REQ E+ +Q++ E + K + ++ L+S
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 63 STVGLVTLNDMKAKQEALVK---------EREKQLAKKEQSKELQMKLEKLREKERKKEA 113
+ + ++E L+K ER +Q K+EQ E+ R++ K+E
Sbjct: 535 EQQ---LRREQEERREQLLKREEEKRLEQERREQRLKREQ--------EERRDQLLKREE 583
Query: 114 KRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDRE 173
+R+ L EE E + EE E+E RE+ R + P+ + + E
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQ-----RLKREEPEEERRQQLLKSEE 638
Query: 174 EEENRLREELRQEWEAKQEKIKSEEIE 200
+EE R ++ R++ E +++++K EE E
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEE 665
Score = 55.1 bits (131), Expect = 9e-08
Identities = 53/242 (21%), Positives = 117/242 (48%), Gaps = 21/242 (8%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+++E++R+ + K + EE ++ +K+ + E + +++ ++E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE----------ELQQEEE 1001
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKE---RKKEAKRKISSLSFTLEEEEEGGEEEE 135
L++E ++ ++E ++ + K E +E+E R++ KR++ EEEE +EEE
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 136 EAAMYEEE-MEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKI 194
+ E E R+E+ + RK + + L REE E R R+E R+ ++E++
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLL----REEPEKRRRQE-RERQCREEEEL 1116
Query: 195 KSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVEQLMYIKE 254
+ EE ++ + RR R+ ++ Q+ ++LR++ + R +E+ +E
Sbjct: 1117 QQEEEQLLRE--EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 255 DL 256
+L
Sbjct: 1175 EL 1176
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/180 (20%), Positives = 91/180 (50%), Gaps = 5/180 (2%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
+RE+Q E+ +Q + R E+ + + +++ + E + + ++ +QE
Sbjct: 287 RRERQEEEQQQQRLR-REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE- 344
Query: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAM 139
+ RE+QL ++++ + + +L + +E+ER+++ R+ L + E E+
Sbjct: 345 --ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 140 YEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE-LRQEWEAKQEKIKSEE 198
E+++ RE+ ++++L + + +R ++ E RE+ L++E E +++ +K EE
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Score = 54.7 bits (130), Expect = 1e-07
Identities = 51/233 (21%), Positives = 108/233 (46%), Gaps = 13/233 (5%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK-- 76
+K+E QR + EQ ++R E+ ++ +++ AH E E + + +
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEER--AHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 77 -----QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGG 131
+ L ++RE+QL +E+ + Q L + EKE+++ +R+ LEEEE+
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRL--REELRQEWEA 189
E + EEE +E ++R + D + + +R+ + L + L+++
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 190 KQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELR 242
+Q+ ++ EE E+ + RR + R+ +Q Q+ ++LR++ + R
Sbjct: 902 EQQLLQEEEEELQRE--EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Score = 54.3 bits (129), Expect = 2e-07
Identities = 52/237 (21%), Positives = 110/237 (46%), Gaps = 42/237 (17%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L+++RE+Q + ++ ++ EE + +KF ++ +
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKF-----------------------LEEE 1380
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLRE------KERKKEAKRKISSLSFTLEEEEEG 130
Q +ERE++ K+EQ Q + ++LR+ +E +++ R+ F EE++
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 131 GEEEEEAAMYEEEMEREEITTKKR---KLGKNPDVDTSFLPDRDRE--EEENRLREELRQ 185
+E E + EE+ R+E K R +L + + +RDR+ EEE +LR + R
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 186 EWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELR 242
+ ++++++S+E E F + HR+ ++FLQ+ ++ R++ + R
Sbjct: 1501 R-KFREQELRSQEPERKFLEEEQQLHRQ-------QRQRKFLQEEQQLRRQERGQQR 1549
Score = 53.1 bits (126), Expect = 3e-07
Identities = 60/251 (23%), Positives = 109/251 (43%), Gaps = 36/251 (14%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKA 75
++RE+Q Q K R E+ + + D+KF V E E K +
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 76 K---QEALVKEREKQ----------LAKKEQSKELQMKLEKLREKE-RKKEAKRKISSLS 121
K +E L++ERE+Q ++EQ Q + K RE+E R +E +RK
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF---- 1517
Query: 122 FTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPD---RDREEEENR 178
LEEE++ ++ + +EE +++ ++R + D D F + R EE+
Sbjct: 1518 --LEEEQQLHRQQRQRKFLQEE---QQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Query: 179 LREELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDF 238
R+E +++ +++K++ +E E F ++R+ QQ Q+ R+D
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFM-------EDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 239 SELRSAGVEQL 249
L+ +QL
Sbjct: 1626 QLLQEREEQQL 1636
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/188 (22%), Positives = 96/188 (51%), Gaps = 19/188 (10%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
R L++ R K RE+ +Q + R ++ + + +K++ + E + L +
Sbjct: 211 RRRELLELRRKGREEKQQQR-RERQDRVFQEEEEKEWRKRETVLRKEEEK-------LQE 262
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
+ +++ ++E E+QL K E+ +++ E+ E+++++ +R+ ++EEE E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQ---ELRRERQEEEQQQQRLRRE---QQLRRKQEEERRE 316
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELR--QEWEAK 190
++EE E+ ER E ++R+ + + RE+EE R ++LR QE E +
Sbjct: 317 QQEER---REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
Query: 191 QEKIKSEE 198
+++++ E+
Sbjct: 374 EQQLRREQ 381
Score = 52.4 bits (124), Expect = 6e-07
Identities = 38/180 (21%), Positives = 93/180 (51%), Gaps = 15/180 (8%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+++ +++++++Q ++++ E K + ++ + + E + + + L + + +QE
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL-LGEERETRRRQE 1075
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
+ R+++ ++E+ + L+ + EK R +ER+++ + EEEE EEE+
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR----------EEEELQQEEEQLLR 1125
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEE 198
E+ R+E+ + R+ + + L REE E R R+EL +++ ++E + EE
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLL----REEPEKRRRQELERQYREEEELQQEEE 1181
Score = 52.0 bits (123), Expect = 8e-07
Identities = 41/185 (22%), Positives = 92/185 (49%), Gaps = 10/185 (5%)
Query: 23 KQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVK 82
+QR++ ++ ++R AEE ++S + D E +L+ + + + KQ+ +
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPD--EEQLRRRELLELRRKGREEKQQQR-R 231
Query: 83 EREKQLAKKEQSKE-------LQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
ER+ ++ ++E+ KE L+ + EKL+E+E +++ + + E +E E +
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
E ++ + RE+ +K++ + + RE++E R ++LR+E E ++E+
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 196 SEEIE 200
E E
Sbjct: 352 RREQE 356
Score = 51.2 bits (121), Expect = 1e-06
Identities = 62/252 (24%), Positives = 116/252 (46%), Gaps = 21/252 (8%)
Query: 10 EAGRAMHLMKKREKQREQMEQMKQRIAEEN--IMKSNIDKKFSAHYDAV---EAELKSST 64
E R H + + +EQ+ + +Q + EE + + +K+ + E +L+
Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTL 124
L L + + K+ +ER+ + KK Q KE Q+ E+ EK R++E ++K
Sbjct: 941 EQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEE-PEKRRRQEREKKYR------ 991
Query: 125 EEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELR 184
EEEE EEE+ E+ R+E + RK + + L + E E+ RL+E R
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE---EREKRRLQERER 1048
Query: 185 QEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSA 244
Q E +E+++ EE ++ + RR R+ ++ Q+ ++LR++ + R
Sbjct: 1049 QYRE--EEELQQEEEQLLGE--ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 245 GVEQLMYIKEDL 256
E+ +E+L
Sbjct: 1105 ERERQCREEEEL 1116
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/193 (24%), Positives = 95/193 (49%), Gaps = 19/193 (9%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVT 69
R +++RE+Q + E+++Q EE ++ + + + E EL+ L+
Sbjct: 1038 REKRRLQERERQYREEEELQQE--EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 70 LNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEE 129
K +++ ERE+Q ++E ELQ + E+L +ER+K R+ L EEEE
Sbjct: 1096 EEPEKRRRQ----ERERQCREEE---ELQQEEEQLLREEREK---RRRQELERQYREEEE 1145
Query: 130 GGEEEEEAAMYE-EEMEREEITTKKRKLGKNPDVDTSFL---PDRDREEEENRLREELRQ 185
+EEE+ E E+ R+E+ + R+ + + L ++ R+E E + REE
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 186 EWEAKQEKIKSEE 198
+ + ++++ + E+
Sbjct: 1206 QRQKRKQRYRDED 1218
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/271 (21%), Positives = 124/271 (45%), Gaps = 38/271 (14%)
Query: 7 AASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVG 66
A ++ R + R REQ E +Q AEE + +++F + E +
Sbjct: 773 AEEKSERGRQRLSARPPLREQRE--RQLRAEERQQR---EQRFLPEEEEKEQRRRQRR-- 825
Query: 67 LVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKE--RKKEAKRKISSLSFTL 124
+ ++E E E+QL ++E++++LQ + + L+E + R+ + +R+ + L
Sbjct: 826 -------EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878
Query: 125 EEE---------------EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPD 169
EEE E+ +E++ EEE++REE ++R+ + + L
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 170 RD----REEEENRLREELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQ 225
+ REE E R R+E +++ K +K++ +E ++ + RR + +K ++
Sbjct: 939 EEEQLLREEREKRRRQERERQYR-KDKKLQQKEEQLLGE--EPEKRRRQEREKKYREEEE 995
Query: 226 FLQKALEILRKDFSELRSAGVEQLMYIKEDL 256
Q+ ++LR++ + R E+ K++L
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/248 (22%), Positives = 107/248 (43%), Gaps = 43/248 (17%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLND 72
RA L ++ + +E E+ + + + D+K+ + + + L +
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQ-------EQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 73 MKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
K++ L++E E++L ++E REK R++E +R+ EEE+ +
Sbjct: 898 QLRKEQQLLQEEEEELQREE------------REKRRRQEQERQY-------REEEQLQQ 938
Query: 133 EEEEAAMYEEE----MEREEITTKKRKLGKNPDVDTSFLPD-RDREEEENRLREELRQEW 187
EEE+ E E ERE K +KL + + P+ R R+E E + REE +E
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE--EEL 996
Query: 188 EAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSELRSAGVE 247
+ ++E++ EE E RR + + + LQ+ E L ++ E R
Sbjct: 997 QQEEEQLLREERE----------KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 248 QLMYIKED 255
+ Y +E+
Sbjct: 1047 ERQYREEE 1054
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/267 (25%), Positives = 118/267 (44%), Gaps = 26/267 (9%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELK-------- 61
R + R+++ + EQ++Q E+ + + D+KF V E E K
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Query: 62 ---SSTVGLVTLNDMKAKQ-EALVKER-EKQLAKKEQSKELQMKLEKLREKERKKEAK-- 114
L D K ++ E L++ER E+QL ++E+ ++ + +LR +ER+++ +
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD 1664
Query: 115 --RKISSLSFTLEEEEEG--GEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDR 170
RK L+E EE +E + EEE + +++ L + + L +
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 171 DREEEENRLREELRQEWEAKQEKI-KSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQK 229
REEE+ LR+E QE +QE+ K E E + RR + RK +Q Q+
Sbjct: 1725 FREEEQ--LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 230 ALE-ILRKDFSELRSAGVEQLMYIKED 255
E LR S+ + EQL +E+
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREE 1809
Score = 50.4 bits (119), Expect = 2e-06
Identities = 52/234 (22%), Positives = 107/234 (45%), Gaps = 23/234 (9%)
Query: 13 RAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELK----SSTV 65
R L R+++ + EQ+ Q E+ + + D+KF + E E K +
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 66 GLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLE 125
L ++E L +E E++ ++++ ++ E+LR + +++ +R+ F
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF--R 1774
Query: 126 EEEEGGEEEEEAAMYEEEMER-----EEITTKKRKLGKNPDV-DTSFLPDRDR---EEEE 176
EEE+ +E EE + +E +R E++ ++ + P D + + ++ EE+E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 177 NRLREELRQEWEAK-----QEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQ 225
RLR+E +++ A+ QEK + EE E+ R K+R+ + +Q
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Score = 49.7 bits (117), Expect = 4e-06
Identities = 42/199 (21%), Positives = 93/199 (46%), Gaps = 18/199 (9%)
Query: 3 QYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKS 62
Q G E R L ++ K+ E ++ +Q + EE + +++ E EL+
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE---EEELQQ 1118
Query: 63 STVGLVTLNDMKAKQEAL---------VKEREKQLAKKEQSKELQMKLEK-LREKERKKE 112
L+ K +++ L V++ E+QL ++E K + +LE+ RE+E ++
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 113 AKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR 172
+ ++ EE+E+ +E E EEE++R++ + R + D+ + P+++
Sbjct: 1179 EEEQLLR-----EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233
Query: 173 EEEENRLREELRQEWEAKQ 191
+N++ + R+ + +Q
Sbjct: 1234 AVRDNKVYCKGRENEQFRQ 1252
Score = 49.3 bits (116), Expect = 5e-06
Identities = 38/185 (20%), Positives = 95/185 (51%), Gaps = 10/185 (5%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L ++R ++ + EQ+ Q E+ + + D+KF + + + L + +
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
++ L E E+QL ++++ ++ + ++LR +ER ++ +R+ F EEE+ +E EE
Sbjct: 1515 RKFL--EEEQQLHRQQRQRKFLQEEQQLRRQERGQQ-RRQDRDRKF--REEEQLRQEREE 1569
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRD---REEEENRLREELRQEWEAKQEK 193
+ +E +R + +++K+ + + + F+ D R+E + +LR+E +++ ++
Sbjct: 1570 QQLSRQERDR-KFRLEEQKV-RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 194 IKSEE 198
++ E
Sbjct: 1628 LQERE 1632
Score = 48.5 bits (114), Expect = 8e-06
Identities = 35/180 (19%), Positives = 86/180 (47%), Gaps = 13/180 (7%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
K+R+++ ++ +Q+ + EE + D+KF ++ + +QE
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL----------RRQE 1357
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
K RE++L +EQ ++ + ++LR +ER+++ ++ L E++ + + +
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEE 198
E+++ R+E + RK + +R EEE +LR+E +++ +++ ++ E
Sbjct: 1418 EEEQQLSRQE---RDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/199 (21%), Positives = 97/199 (48%), Gaps = 10/199 (5%)
Query: 22 EKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALV 81
E++ + EQ++Q +E + + +K + + E + + + ++E L
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEE-EQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 82 KEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYE 141
+ERE+Q + ++S + E+LR++ +++ + + + EEE+ EE+E+ E
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Query: 142 EEME---REEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE-LRQEWEAKQEKIKSE 197
+ + E+ T+++ + ++ R R+E E +LREE +R++ + +Q +
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKR-RQERERKLREEHIRRQQKEEQRHRQVG 1899
Query: 198 EIEITFSYWDGSGHRRTVK 216
EI+ +G GH R ++
Sbjct: 1900 EIKSQ----EGKGHGRLLE 1914
Score = 47.8 bits (112), Expect = 1e-05
Identities = 55/252 (21%), Positives = 120/252 (47%), Gaps = 33/252 (13%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTLNDMKA 75
++RE+Q E+ EQ ++R +E + + ++ + E E + L + +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 76 KQEALVKE----REKQLAKKEQ-SKELQMKLEK-LREKERKKEAKRKISSLSFTLEEEEE 129
+++ L +E RE+QL +++Q +E Q++ E+ LR +++ + ++ E+EEE
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 130 GGEEEEEAAMYEEEMERE-----------EIT------TKKRKLGKNPDVDTS----FLP 168
E++ E E+ ++RE E T +K++L ++ + + L
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 169 DRDREEEENRLREELRQEWEAKQE---KIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQ 225
+ +R E++ R ++LR+E E ++E K + EE + RR + R+ +++
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 226 FLQKALEILRKD 237
+K LE R++
Sbjct: 553 EEEKRLEQERRE 564
Score = 46.6 bits (109), Expect = 3e-05
Identities = 52/258 (20%), Positives = 117/258 (45%), Gaps = 43/258 (16%)
Query: 17 LMKKREKQREQMEQMKQRIAEEN--IMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDM- 73
L+++RE+Q+ ++ ++ EE + + D+KF E EL+S L +
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR------EQELRSQEPERKFLEEEQ 1522
Query: 74 ---KAKQEALVKEREKQLAKKEQSKELQM-------KLEKLREKERKKEAKRKISSLSFT 123
+ +++ + E+QL ++E+ ++ + + E+LR++ +++ R+ F
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 124 LEEEEEGGEEEEEAAMYEEE------------MEREEITTKKRKLGKNPDVDTSFLPDRD 171
LEE++ +E+E M +E+ ER+ + +L + + +RD
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 172 RE--EEENRLREELRQEW----------EAKQEKIKSEEIEITFSYWDGSGHRRTVKMRK 219
R+ EEE +LR + R++ E +Q + EE ++ D ++R+
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 220 GNTMQQFLQKALEILRKD 237
++FLQ+ ++ R++
Sbjct: 1703 QERERKFLQEEQQLRRQE 1720
Score = 42.4 bits (98), Expect = 6e-04
Identities = 43/221 (19%), Positives = 100/221 (45%), Gaps = 37/221 (16%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEAL 80
RE++ Q ++ KQR +E+ +S++ ++ + + K G + E
Sbjct: 1200 REEEELQRQKRKQRYRDED-QRSDLKWQWEPEKENAVRDNKVYCKG--------RENEQF 1250
Query: 81 VKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMY 140
+ + QL ++ ++LQ L + +E++R++E +R ++ +
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR---------------WQQRDRHFPE 1295
Query: 141 EEEMEREEITTKKRKLGKNPDVDTSFLPDRD----REEEENRLREELRQEWEAKQEKIKS 196
EE++EREE KR+ K+ + +R+ R+E + + REE + E +++ ++
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 197 EEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKD 237
+E + F R ++R ++FL++ + R++
Sbjct: 1356 QERDRKF---------REEELRHQEQGRKFLEEEQRLRRQE 1387
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 16/188 (8%)
Query: 77 QEALVKER---EKQLAKKEQSKEL-----QMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
+E+L+++R E Q + + ++L Q + +K +E+ER+ + S LE+ +
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 129 EGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPD------RDREEEENRLREE 182
+EE +E EREE ++ +L +T PD R+ E + REE
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 183 LRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTM-QQFLQKALEILRK-DFSE 240
+Q+ +Q+++ EE E + + + K+++ Q+ LQ+ E LRK + E
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 241 LRSAGVEQ 248
LR E+
Sbjct: 286 LRRERQEE 293
Score = 38.9 bits (89), Expect = 0.007
Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 34/187 (18%)
Query: 12 GRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLN 71
G+ L +R+++ ++ + + R EE + K+ + E E +S
Sbjct: 105 GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE-------- 156
Query: 72 DMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGG 131
KQE L ++R++Q + +EL + ++ +E+E ++ + ++ S G
Sbjct: 157 ----KQERL-EQRDRQ----RRDEELWRQRQEWQEREERRAEEEQLQSCK---------G 198
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQ 191
E EE EE++ R E+ +RK G+ + RE ++ +EE +EW ++
Sbjct: 199 HETEEFP-DEEQLRRRELLELRRK-GREEK------QQQRRERQDRVFQEEEEKEWRKRE 250
Query: 192 EKIKSEE 198
++ EE
Sbjct: 251 TVLRKEE 257
Score = 38.9 bits (89), Expect = 0.007
Identities = 48/225 (21%), Positives = 97/225 (43%), Gaps = 27/225 (12%)
Query: 19 KKREKQREQMEQMKQRIAEEN-IMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMK--- 74
K RE++ EQ ++ + EE + + ++KF + + + L D K
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ--LRQDRDRKFRE 1418
Query: 75 -----AKQEALVK--EREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEE 127
++QE K E E+Q+ ++E+ ++ + ++LR++ +K EE
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK------------FREE 1466
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEW 187
E+ +E EE ++ +E +R+ + +++ + D R +E E L EE +
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 188 EAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALE 232
+ +Q K EE ++ + RR + RK +Q Q+ E
Sbjct: 1527 QQRQRKFLQEEQQLRRQ--ERGQQRRQDRDRKFREEEQLRQEREE 1569
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 57.8 bits (138), Expect = 1e-08
Identities = 49/185 (26%), Positives = 94/185 (50%), Gaps = 49/185 (26%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
K+RE++ +ME+ ++ E + + +D+K L L + +E
Sbjct: 464 KRREEEERRMEEQRKAACAEKLKR--LDEK------------------LGILEKQPSPEE 503
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
+EREK+ +E+ KEL+ + E+ REKER+K+ +R+ +E+E+ E+E+E
Sbjct: 504 IREREREKE---REREKELEKEQEQEREKEREKDRERQ--------QEKEKELEKEQEK- 551
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE-----ELRQEWEAKQEK 193
+ EME+E K+++L + +++E+E +++E EL +E E +EK
Sbjct: 552 --QREMEKERKQEKEKELERQ----------KEKEKELQKMKEQEKECELEKEREKLEEK 599
Query: 194 IKSEE 198
I+ E
Sbjct: 600 IEPRE 604
Score = 54.7 bits (130), Expect = 1e-07
Identities = 48/168 (28%), Positives = 86/168 (51%), Gaps = 5/168 (2%)
Query: 32 KQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKK 91
KQ++A+E+ + ++ S AVE K M+ +++A E+ K+L +K
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREE---EERRMEEQRKAACAEKLKRLDEK 491
Query: 92 EQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITT 151
E Q E++RE+ER+KE +R+ L E+E E E++ E+E E E+
Sbjct: 492 LGILEKQPSPEEIREREREKERERE-KELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 152 KKRKLGKNPDVDTSFLPDRDRE-EEENRLREELRQEWEAKQEKIKSEE 198
K+R++ K + +R +E E+E + +E +E E ++E+ K EE
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
Score = 36.2 bits (82), Expect = 0.043
Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 60/193 (31%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L K++EKQRE ++ KQ K K
Sbjct: 545 LEKEQEKQREMEKERKQE---------------------------------------KEK 565
Query: 77 QEALVKEREKQLAK-KEQSK--ELQMKLEKLREKERKKE------AKRKISSLSFTLEEE 127
+ KE+EK+L K KEQ K EL+ + EKL EK +E +++ S S EEE
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Query: 128 -----EEGGEEEEEAAMYEEEMEREEITTKKRKL--GKNPDVDTSFLPDRDREEEENRLR 180
++ E+EA E E E + + + G S P R++E+ +
Sbjct: 626 PVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMK-- 683
Query: 181 EELRQEWEAKQEK 193
+Q+W+ +Q++
Sbjct: 684 ---QQQWQQQQQQ 693
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 56.2 bits (134), Expect = 4e-08
Identities = 53/208 (25%), Positives = 90/208 (43%), Gaps = 19/208 (9%)
Query: 19 KKREKQREQMEQMK-QRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
+KR+ RE+ Q K +R E+ + ++ + E E D +
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE-----------RDRDRDR 272
Query: 78 EALVKEREKQLAKK-----EQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGE 132
+ KERE+Q +K E+ +E + K E+ RE+ER++E RK E E E
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK-RERERERERERERQR 331
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
E E E E +R+ T R+ + + +R+RE E R R+ R+ E +++
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 193 KIKSEEIE-ITFSYWDGSGHRRTVKMRK 219
+ + + E + D G R T K R+
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQRE 419
Score = 55.5 bits (132), Expect = 7e-08
Identities = 47/194 (24%), Positives = 89/194 (45%), Gaps = 4/194 (2%)
Query: 9 SEAGRAMHLMKKREKQRE-QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGL 67
++ R + EK+RE Q ++ +QR E N K +K E + +
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK-T 201
Query: 68 VTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEE 127
+ + ++ +E E + +K Q+ + + ++ E+ER+K+A+R+ +S T ++
Sbjct: 202 EDRHSERGRERERERETETETERKRQT-DRERDRQRKTEREREKQAERERASERETERDK 260
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ-E 186
E E + + + ERE T +KR+ D +T +R RE E R R R+ E
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 187 WEAKQEKIKSEEIE 200
E ++E+ + E E
Sbjct: 321 RERERERERQRETE 334
Score = 49.7 bits (117), Expect = 4e-06
Identities = 49/183 (26%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 19 KKREKQREQM---EQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKA 75
+ REK+RE+ E+ +QR E N K + E E + +
Sbjct: 99 RDREKERERQTDRERDRQREKERNRQKERERE--------TEREGERGRDRQTDGQRERE 150
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+Q KERE+Q +E Q + E+ R+KER++E R+ E+E E+
Sbjct: 151 RQRDAEKERERQT-----DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
E E ERE T +RK + + D +R+RE++ R E E E +++K +
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER---ERASERETERDKER 262
Query: 196 SEE 198
E
Sbjct: 263 ERE 265
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 6/123 (4%)
Query: 82 KEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYE 141
KERE++ K++ +E K E+ REK+R ++ R +E E + E + +
Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREK 119
Query: 142 E---EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE---ELRQEWEAKQEKIK 195
E + ERE T ++ + G++ D +R R+ E+ R R+ E +++ E ++K +
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179
Query: 196 SEE 198
E
Sbjct: 180 ERE 182
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 82 KEREKQLAK-KEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMY 140
+ RE+Q + KE+ ++ + ++ REKER ++ +R+ + E E E G + +
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERET-----EREGERGRDRQTDGQR 147
Query: 141 EEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
E E +R+ ++R+ + T ++RE E+NR R+ K+ K + E
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
Score = 45.4 bits (106), Expect = 7e-05
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 16/125 (12%)
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
+ +Q KERE+Q ++ ++ Q + E+ R+KER++E +R+ + + +G E
Sbjct: 95 RERQRDREKERERQT---DRERDRQREKERNRQKERERETEREGER---GRDRQTDGQRE 148
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
E E+E ER+ ++R+ +N R +E E + R+E R+ ++++
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERN----------RQKEREREKNRQERRERERQREKE 198
Query: 194 IKSEE 198
K+E+
Sbjct: 199 NKTED 203
Score = 43.5 bits (101), Expect = 3e-04
Identities = 45/195 (23%), Positives = 89/195 (45%), Gaps = 16/195 (8%)
Query: 9 SEAGRAMHLMKKREKQRE-QMEQMKQRIAEENIMKSNIDKKFSAHYDAV-EAELKSSTVG 66
+E RA +R+K+RE + ++ + R + + D+K + E E K
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Query: 67 LVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEE 126
+ ++ +ERE++ +E+ +E + EK RE++RK++ + E
Sbjct: 306 ERERERERNRKRERERERERE---RERQRETERDREKERERKRKRQTE-------MDRER 355
Query: 127 EEEGGEEEEEAAMYEEEMERE-EITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ 185
+ G E A E E ERE + + + + + D D +R+R+ E++R + ++
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDR---DGQR 412
Query: 186 EWEAKQEKIKSEEIE 200
E E ++E+ K E E
Sbjct: 413 ETEKQREREKDRESE 427
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/170 (21%), Positives = 78/170 (45%), Gaps = 22/170 (12%)
Query: 19 KKREKQRE---QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKA 75
+KRE+QRE + E+ ++R E + ++ + E E K +
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERK------------RK 346
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+Q + +ER +Q ++ + + RE+ER++E R+ + E + + ++E
Sbjct: 347 RQTEMDRERNRQTGREGRR-------QAERERERERERDRQSAREREERERDRDRDRQKE 399
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQ 185
E++ + + T K+R+ K+ + + R+RE+++ R R+ RQ
Sbjct: 400 RERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/170 (23%), Positives = 82/170 (48%), Gaps = 24/170 (14%)
Query: 10 EAGRAMHLMKKREKQRE-QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLV 68
E R +KRE++RE + E+ +QR E + K K+ ++ E T
Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKR--KRQTEMDRERNRQT---- 359
Query: 69 TLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
+ +++A +ERE++ + QS + + E+ R+++R+KE +R+ E++
Sbjct: 360 ---GREGRRQA-ERERERERERDRQSAREREERERDRDRDRQKERERQT-------EKDR 408
Query: 129 EGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENR 178
+G E E+ + E E++ + + R+ G+ + +RDRE + +R
Sbjct: 409 DGQRETEK----QREREKDRESERGRERGREREKQKG--RERDRERQTDR 452
Score = 33.9 bits (76), Expect = 0.21
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
Query: 105 REKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDT 164
RE+ R+KE +R+ + E E + E + +R+ ++R K + T
Sbjct: 54 RERNRQKERERRREK----RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQT 109
Query: 165 SFLPDRDREEEENRLREELRQ 185
DR RE+E NR +E R+
Sbjct: 110 DRERDRQREKERNRQKERERE 130
Score = 29.3 bits (64), Expect = 5.3
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 125 EEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELR 184
++ E ++E E + + ERE T +KR+ + + D DR RE + +R +E R
Sbjct: 52 DDRERNRQKERERRREKRQTERE--TDRKRE--RRREKDRHRKRDRHRERQRDREKERER 107
Query: 185 Q---EWEAKQEKIKSEEIE 200
Q E + ++EK ++ + E
Sbjct: 108 QTDRERDRQREKERNRQKE 126
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/119 (32%), Positives = 66/119 (55%), Gaps = 19/119 (15%)
Query: 72 DMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGG 131
+ + K++ KE+ K+ KK+++KE + + EK E+E+K++ KRK +EEEE
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK-EEEEKKRKRKRKKK------KEEEERE 76
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE +EE E+EE +K+K R R+EEE +++ R++ + K
Sbjct: 77 EEEEEEEEEKEEEEKEEGRRRKKK------------KKRRRKEEEEEKKKKRRRKTKKK 123
Score = 48.9 bits (115), Expect = 6e-06
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 19/127 (14%)
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
K K++ + E + ++E+ KE + K EK +EK ++KE K+K E+EEE +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
+ + +EE EREE + + EE+E +EE R+ + K+ +
Sbjct: 63 KRKRKKKKEEEEREE------------------EEEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 194 IKSEEIE 200
K EE E
Sbjct: 105 RKEEEEE 111
Score = 45.1 bits (105), Expect = 9e-05
Identities = 25/93 (26%), Positives = 49/93 (52%)
Query: 105 REKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDT 164
++K++KK+ + T EEEE+ G+ +E+ +E E+++ T + K + + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 165 SFLPDRDREEEENRLREELRQEWEAKQEKIKSE 197
R +++EE EE +E E K+E+ K E
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/122 (24%), Positives = 59/122 (48%), Gaps = 12/122 (9%)
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
K K+E E ++ ++E+ + + + K + KE++K+ K K + EEEE+ +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
+ + EEE E EE ++ K + ++EE R +++ R+ E ++EK
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEK------------EEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 194 IK 195
K
Sbjct: 113 KK 114
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 55.8 bits (133), Expect = 5e-08
Identities = 41/184 (22%), Positives = 93/184 (50%), Gaps = 27/184 (14%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ K+ E+ REQ EQM+++ EE ++K + E E + +
Sbjct: 257 MRKQEEQMREQEEQMREQ--EEQMLKQK---------EQTEQE------------EQTGE 293
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERK--KEAKRKISSLSFTLEEEEEGGEEE 134
QE ++E+E+Q+ +EQ ++++ + E++RE+E + K+ ++ E++E+ ++E
Sbjct: 294 QEEQMREQEEQM--REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
Query: 135 EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKI 194
E+ EE+M+++E +K++ + + ++E ++ E+ Q E K++
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMR 411
Query: 195 KSEE 198
+ EE
Sbjct: 412 EQEE 415
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/209 (21%), Positives = 100/209 (47%), Gaps = 10/209 (4%)
Query: 1 MAQYKGAASEAGRAM-----HLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDA 55
M + +G E M + K+ E+ EQ EQM+++ + + + K+
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 56 VEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKR 115
E K M+ ++E ++K++E Q ++EQ+ E + ++ + E+ R++E +
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKE-QTEQEEQTGEQEEQMREQEEQMREQEEQM 312
Query: 116 KISSLSFTLEEEEEGGEEEEEAAMYEEEME-REEITTKKRKLGKNPD-VDTSFLPDRDRE 173
+ +EE+ G +EE+ E+ E +E++ ++ ++G+ + + R +E
Sbjct: 313 REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 174 EEENRLREELRQEWE--AKQEKIKSEEIE 200
E+ + E++R++ E KQE+ E+ E
Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Score = 48.1 bits (113), Expect = 1e-05
Identities = 33/155 (21%), Positives = 80/155 (51%), Gaps = 11/155 (7%)
Query: 10 EAGRAMHLMKKREKQ-REQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLV 68
+ G M+++E+Q REQ EQM+++ + + + K+ ++ E +
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK----- 344
Query: 69 TLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
+ KQE + E+E+Q+ K+E+ Q + + +E++ +K+ ++ E++E
Sbjct: 345 ---EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Query: 129 EGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPD 161
+ GE++E+ EE+M ++E++ ++ +G+ +
Sbjct: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 45.4 bits (106), Expect = 7e-05
Identities = 31/128 (24%), Positives = 68/128 (53%), Gaps = 16/128 (12%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
+QE V+E+E Q+ ++E Q + +E++ +K+ ++ ++EE+ GE+EE
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE---LRQEWEAKQE 192
+ EE+++++E +K++ ++ RE+EE +E L+Q+ + +QE
Sbjct: 242 QVQKQEEQVQKQEEQMRKQE-------------EQMREQEEQMREQEEQMLKQKEQTEQE 288
Query: 193 KIKSEEIE 200
+ E+ E
Sbjct: 289 EQTGEQEE 296
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/126 (23%), Positives = 70/126 (55%), Gaps = 7/126 (5%)
Query: 76 KQEALVKEREKQLAKKE-QSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEE 134
+QE V+E+E Q+ ++E Q +E + ++ + + R++E + +EE+ G E+E
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMG-EQE 212
Query: 135 EEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
E+ EE+M + E++ ++ ++G+ + ++EE+ R +EE +E ++E
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE---QEE 269
Query: 193 KIKSEE 198
+++ +E
Sbjct: 270 QMREQE 275
Score = 33.5 bits (75), Expect = 0.28
Identities = 27/125 (21%), Positives = 65/125 (52%), Gaps = 4/125 (3%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEGGEEE 134
+QE V+E+E Q+ +EQ +++ + ++RE+E + +E + ++ + E+E E+
Sbjct: 112 EQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169
Query: 135 EEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAKQEK 193
E +E RE+ + + G+ + + ++ E+E +++++ Q E +++
Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
Query: 194 IKSEE 198
K EE
Sbjct: 230 RKQEE 234
Score = 30.8 bits (68), Expect = 1.8
Identities = 32/147 (21%), Positives = 71/147 (48%), Gaps = 13/147 (8%)
Query: 91 KEQSKELQMKLEKLREKERK-----KEAKRKISSLSFTLEE-----EEEGGEEEEEAAMY 140
KE++ ELQ +L+ + ++ + KE KRK+ + L + E+EG E+E +
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
Query: 141 EEEME-REEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAKQEKIKSEE 198
E+E + RE+ + + G+ + + + E+E ++RE+ Q E ++ +++ +E
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQVREQE 128
Query: 199 IEITFSYWDGSGHRRTVKMRKGNTMQQ 225
++ V+ ++G +Q
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQ 155
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 55.5 bits (132), Expect = 7e-08
Identities = 51/216 (23%), Positives = 97/216 (44%), Gaps = 28/216 (12%)
Query: 5 KGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSST 64
K E R ++RE++RE+ + ++ E + DKK D +A +
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK- 445
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTL 124
L ++EA +ER K +E+ K + + E RE+ER++E ++ L L
Sbjct: 446 -----LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 125 EEEEEGG------------------EEEEEAAMYEEEMEREEITTKKRKL--GKNPDVDT 164
E+ ++ E+E EA + + E+EE+ +++L +PD D
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA 560
Query: 165 SFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
R +E E R + +++QE E+++E+ + +E E
Sbjct: 561 EL--QRMEQEAERRRQPQIKQEPESEEEEEEKQEKE 594
Score = 49.7 bits (117), Expect = 4e-06
Identities = 43/206 (20%), Positives = 87/206 (42%), Gaps = 31/206 (15%)
Query: 25 REQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKER 84
+E + ++ + +++ I K H E + K + + ++ +ER
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER 320
Query: 85 EKQLAKKEQSKELQMKLEKLREKERKKEAKR-------------------------KISS 119
E++ ++E+ +E + + EK RE+ER+++ R +
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 120 LSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEEN-- 177
S + E+ + E E E E ERE ++R+ + + + RDREE+E
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 178 ----RLREELRQEWEAKQEKIKSEEI 199
+L +LR++ A QE++K+ EI
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEI 466
Score = 48.9 bits (115), Expect = 6e-06
Identities = 46/186 (24%), Positives = 85/186 (45%), Gaps = 19/186 (10%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAE-----LKSSTVGLVTLNDMKA 75
R+K++E+ E + +R ++ + K +A+E E L S + K
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITK--EDINAIEMEEDKRDLISREISKFRDTHKKL 291
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
++E KE+E+Q +KE+ RE+ER++E +R+ E E E +E+E
Sbjct: 292 EEEKGKKEKERQEIEKER-----------RERERERERERERREREREREREREREKEKE 340
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELR-QEWEAKQEKI 194
E + +R+ + R + D D DR ++ +R RE+ R +E E ++E+
Sbjct: 341 RERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE 400
Query: 195 KSEEIE 200
+ E E
Sbjct: 401 RERERE 406
Score = 46.6 bits (109), Expect = 3e-05
Identities = 60/257 (23%), Positives = 105/257 (40%), Gaps = 29/257 (11%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
++RE++RE+ E+ ++R E K +++ D K D +E
Sbjct: 314 RERERERERREREREREREREREKEK-ERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
+ + +E+S++ E+ RE+ER++E +R+ E E E E E
Sbjct: 373 RSSDRNKDRSRSREKSRDR----EREREREREREREREREREREREREREREREREREKD 428
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDR-----------DREEEENRLREELRQEW 187
+ E EE ++RKL + + +R RE E+ REE R+
Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Query: 188 EAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFL---QKALEILRKDFSELRSA 244
AK+ K E +E D R K +G+ +Q+ L +K +E +D R
Sbjct: 489 MAKEAKRLKEFLE------DYDDDRDDPKYYRGSALQKRLRDREKEMEADERD----RKR 538
Query: 245 GVEQLMYIKEDLIIPHH 261
E+L I++ L+ H
Sbjct: 539 EKEELEEIRQRLLAEGH 555
Score = 36.2 bits (82), Expect = 0.043
Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 25/161 (15%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVT--LNDMKAK 76
++ EK+ E+ E+ ++ +A+E + K+F YD + K + L D + +
Sbjct: 473 REYEKEAEREEERRREMAKE----AKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528
Query: 77 QEALVKEREKQLAKKEQSKELQMKL---------EKLREKERKKEAKRKISSLSFTLEEE 127
EA ++R+++ KE+ +E++ +L +L+ E++ E +R+ +++E
Sbjct: 529 MEADERDRKRE---KEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ-----IKQE 580
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLP 168
E EEEEE E+E +REE ++ + + P + + P
Sbjct: 581 PESEEEEEE--KQEKEEKREEPMEEEEEPEQKPCLKPTLRP 619
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.1 bits (131), Expect = 9e-08
Identities = 41/188 (21%), Positives = 91/188 (48%), Gaps = 14/188 (7%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ + KQ E+ EQ I+ M+ ++ A +EAE + +KA+
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERER---------IKAE 283
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
Q+ + + ++ +E++ + + + E+ER +E +++ + ++EEE+ EE +
Sbjct: 284 QDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ 343
Query: 137 AAMYEEEM---EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE- 192
EE+ ER+ I ++++ + + ++ + EE+ R ++L ++ A QE
Sbjct: 344 RIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR-NKQLEEKKHAMQET 402
Query: 193 KIKSEEIE 200
KIK E++E
Sbjct: 403 KIKGEKVE 410
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/212 (23%), Positives = 94/212 (44%), Gaps = 30/212 (14%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
+ ++R + E+++Q+ EE++ + + +A + E K++T T ++ EA
Sbjct: 39 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQVEGDDEA 94
Query: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEE--------EEEGG 131
ER LA++E+ ++ +++ ER+KE I+ S +L E E
Sbjct: 95 AFLER---LARREERRQKRLQ----EALERQKEFDPTITDASLSLPSRRMQNDTAENETT 147
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNP--DVDTSFLPDRDREEEENRLREELRQEWEA 189
E+EE++ +E E EE T + KN D + + D+++EEEE E +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE---------EEKP 198
Query: 190 KQEKIKSEEIEITFSYWDGSGHRRTVKMRKGN 221
K+ I ++E+ TV M N
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/216 (23%), Positives = 102/216 (47%), Gaps = 36/216 (16%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
M++ +K+R + E+ + E +K+ DKK + +EAE K++ +A++
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ---ERERREAEE 313
Query: 78 EALVKEREKQLAK-----KEQSKELQMKLEKLREKER---------KKEAKRKISSLSFT 123
++E EK+ A+ KE+ K + ++++E+E+ K+E KR
Sbjct: 314 RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373
Query: 124 -LEEEEEGGEEEEEA---------AMYEEEMEREEITTK------KRKLGKNPDVDTSFL 167
EEEE+ EE++ AM E +++ E++ K K + + T+ L
Sbjct: 374 RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL 433
Query: 168 PDRDREE--EENRLREELRQEWEA-KQEKIKSEEIE 200
+ E+ + RE+L+++ K+E+IK E+I+
Sbjct: 434 KKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 469
Score = 49.3 bits (116), Expect = 5e-06
Identities = 48/222 (21%), Positives = 103/222 (46%), Gaps = 15/222 (6%)
Query: 8 ASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGL 67
A E A ++ ++RE+M + ++R AEE +K+ + ++ E K +
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE-- 354
Query: 68 VTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKEAKRKISSLSFTLEE 126
+ K+E E+Q A+ E+ ++ +++ +K ++ E KK A ++ +E+
Sbjct: 355 ---ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQE 186
+ EG E+ A E++++ T +K G+ ++ +E++ +EE++ E
Sbjct: 412 KIEGKWVNEKKAQ-EDKLQ----TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 466
Query: 187 WEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQ 228
+ K++K EE++ S+ D VK + G M L+
Sbjct: 467 -KIKKDKEPKEEVK---SFMDRKKGFTEVKSQNGEFMTHKLK 504
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/203 (24%), Positives = 92/203 (45%), Gaps = 25/203 (12%)
Query: 5 KGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSST 64
K SE+ + + +++ E + ++ R AEEN K + +K+ + E + K +
Sbjct: 149 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN-KKEDKEKE-----EEEEEKPKRGS 202
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTL 124
+G + + V EK +E++ + +K ++ +E K+E +R+ S +
Sbjct: 203 IG---------ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISH 253
Query: 125 EE--EEEGGEEEEEAAMYEEEMEREEITTKKRK-----LGKNPDVDTSFLPDRDRE--EE 175
E EEE E E E ERE I ++ K + + + +R+R EE
Sbjct: 254 HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEE 313
Query: 176 ENRLREELRQEWEAKQEKIKSEE 198
R+REE ++ E +Q +IK EE
Sbjct: 314 RERMREEEKRAAEERQ-RIKEEE 335
Score = 37.7 bits (86), Expect = 0.015
Identities = 50/193 (25%), Positives = 84/193 (43%), Gaps = 29/193 (15%)
Query: 20 KREKQREQMEQMK-QRIAEENIMKSNIDKK-FSAHYDAVEA--ELKSSTVGLVTLNDMKA 75
KREK +E K + I +E I K K+ + D + E+KS +T + +K
Sbjct: 447 KREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT-HKLKH 505
Query: 76 KQEALVKEREKQLAKKEQSK-----ELQMKLEKLREKERKKEA----KRKISSLSFTLEE 126
+ + + ++++ E +LE+LR + + E+ K K LE
Sbjct: 506 TENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALEL 565
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREEL-RQ 185
EE + EE + EEE +R + RKL + EEE+ RL+EE+ R+
Sbjct: 566 EELKKKREERRKVLEEEEQRRKQEEADRKLRE--------------EEEKRRLKEEIERR 611
Query: 186 EWEAKQEKIKSEE 198
EA +++ K E
Sbjct: 612 RAEAAEKRQKMPE 624
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 54.7 bits (130), Expect = 1e-07
Identities = 58/192 (30%), Positives = 97/192 (50%), Gaps = 29/192 (15%)
Query: 19 KKREKQREQMEQ---MKQRIA----EENIMKSNIDKKFSAHYDAV---EAELKSSTVGLV 68
+K EK++ E+ + Q+ A EE + K +DK S + A +AE S+ +G
Sbjct: 332 RKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAE-NSAALGKP 390
Query: 69 TLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKER--KKEAKRKISSLSFTLEE 126
T A + A + +++ A+ ++ +E Q ++EK E++R ++E KRK LEE
Sbjct: 391 TAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEK-EEQDRLEREELKRKAEEERLRLEE 449
Query: 127 EEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQE 186
E ++EEE EEE +++E +KRK G+ + + EEE L+E+ QE
Sbjct: 450 EAR--KQEEERKRQEEEKKKQE-GEEKRKAGEEA---------KRKAEEELLLKEKQEQE 497
Query: 187 WEAKQEKIKSEE 198
KQEK E+
Sbjct: 498 ---KQEKAMIEK 506
Score = 45.8 bits (107), Expect = 5e-05
Identities = 41/166 (24%), Positives = 73/166 (43%), Gaps = 12/166 (7%)
Query: 9 SEAGRAMHLM-KKREKQREQMEQMKQRIAE----ENIMKSNIDKKFSAHYDAVEAELKSS 63
++AG A ++ +KR + R Q EQ +Q E + + + + +K +E E +
Sbjct: 395 TDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQ 454
Query: 64 TVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFT 123
+ K KQE K + + AK++ +EL +K ++ +EK+ K +++ +
Sbjct: 455 EEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETK 514
Query: 124 LEEEEEGGEEEEEAAMYEEEMER-------EEITTKKRKLGKNPDV 162
E E E E M + E ER +EI + RK P V
Sbjct: 515 AREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQV 560
Score = 33.5 bits (75), Expect = 0.28
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 14/84 (16%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKK----EAKRKISSLSFTLEEEEEGG 131
+Q+ L K++ +L ++Q +E KLE+ R++E +K E KRK L EEEE
Sbjct: 73 EQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQK-----LREEEERL 127
Query: 132 EEEEEAAMYEEEMEREEITTKKRK 155
E AM +ER + K+K
Sbjct: 128 E-----AMMRRSLERTQQLELKKK 146
Score = 32.7 bits (73), Expect = 0.48
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 3/155 (1%)
Query: 7 AASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVG 66
A E R +K+E++R++ E+ K++ E K+ + K A + + E +
Sbjct: 440 AEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQ 499
Query: 67 LVTLNDMKAKQEALVKERE--KQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTL 124
+ + K K+ A K RE +Q+ + + LQ++ E+L K+R E ++
Sbjct: 500 EKAMIE-KQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPP 558
Query: 125 EEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKN 159
+ ++E + + A+ E+ + + K G N
Sbjct: 559 QVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGLN 593
Score = 32.0 bits (71), Expect = 0.81
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 33/111 (29%)
Query: 82 KEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYE 141
+EREK LA +EQ + K +L+ +++ +E RK+ EE+ E+++ AA+ E
Sbjct: 63 EEREKCLAAREQQILEKQKRARLQYEKQMEERWRKL--------EEQRQREDQKRAAVEE 114
Query: 142 EEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
+ +K+KL EEE RL +R+ E Q+
Sbjct: 115 K---------RKQKL----------------REEEERLEAMMRRSLERTQQ 140
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 54.3 bits (129), Expect = 2e-07
Identities = 46/186 (24%), Positives = 96/186 (51%), Gaps = 37/186 (19%)
Query: 18 MKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQ 77
+++ EK++EQ E +Q EE I + + E+ + ++ ++
Sbjct: 452 IREEEKRQEQEEMWRQ---EEKIRE--------------QEEIWRQKEKMHEQEKIRKQE 494
Query: 78 EALVKEREKQLAKKEQSKELQMKL----EKLREKERK-KEAKRKISSLSFTLEEEEEGGE 132
E + ++ EK ++E+ +E + K+ EK+RE+E K +E + KI ++E+EE
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 133 EEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
E+EE +E+M R+E ++++ ++ RE++E ++RE+ + WE ++E
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQE-------------EKIREQKE-KIREQEEKIWE-QEE 599
Query: 193 KIKSEE 198
KI+ +E
Sbjct: 600 KIREQE 605
Score = 52.8 bits (125), Expect = 4e-07
Identities = 44/187 (23%), Positives = 91/187 (48%), Gaps = 5/187 (2%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
+KR++Q +M + +++I E+ +KK + + + K + +QE
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAA 138
++E+E+ +KE+ E Q K+ K EK ++E K +EE+ +EE+
Sbjct: 469 EKIREQEEIWRQKEKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 139 MYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK----QEKI 194
E+ E+EE ++ ++ + + ++ +E+E+ R +EE +E E K +EKI
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 195 KSEEIEI 201
+ +E +I
Sbjct: 588 REQEEKI 594
Score = 52.4 bits (124), Expect = 6e-07
Identities = 39/192 (20%), Positives = 95/192 (49%), Gaps = 10/192 (5%)
Query: 17 LMKKREKQREQME--QMKQRIAEENIMKSNIDKKFSAHYDAVEAE--LKSSTVGLVTLND 72
+ ++ EK REQ E + K+++ E+ ++ +K + + E ++ + +
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523
Query: 73 MKAKQEALVKEREKQLAKKE-----QSKELQMKLEKLREKERKKEAKRKISSLSFTLEEE 127
+QE ++E+E+++ ++E Q +++ + EK++E+E+ + + KI + E+
Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Query: 128 EEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR-EEEENRLREELRQE 186
+E E+EE +EE RE+ + + K + + ++ +E+E ++R + +
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Query: 187 WEAKQEKIKSEE 198
WE + + EE
Sbjct: 644 WEQEVRLRQQEE 655
Score = 52.0 bits (123), Expect = 8e-07
Identities = 53/197 (26%), Positives = 98/197 (49%), Gaps = 13/197 (6%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFS-AHYDAVEAELKSSTVGL-VTLNDMK 74
L +K K +E+++ ++ +E + + +K A + +L++ L L +
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 278
Query: 75 AKQEALVKERE------KQLAKK--EQSKELQMKLEKLREKERK-KEAKRKISSLSFTLE 125
AK +A V+E E +Q +K Q +++Q EK++E+E K +E + KI +
Sbjct: 279 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 338
Query: 126 EEEEGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREEL 183
+EE E+EE +EEM E+EE + ++ + L ++ E+E+ R +EE
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 184 RQEWEAKQEKIKSEEIE 200
RQE E +E+ K +E E
Sbjct: 399 RQEEEKIREQEKRQEQE 415
Score = 51.6 bits (122), Expect = 1e-06
Identities = 45/202 (22%), Positives = 101/202 (50%), Gaps = 30/202 (14%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
+ ++ EK REQ E+M++ +E +M +K E E K + L +M +
Sbjct: 323 IREQEEKIREQEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEK-----MRRLEEMMWE 374
Query: 77 QEALVKEREKQLAKKEQSKELQMKL---EKLREKERK--------------KEAKRKISS 119
+E ++E E+++ ++E+ +E + K EK+RE+E++ +E + KI
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 120 LSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRL 179
+ +EE E+E+ E+ E+EE+ ++ K+ + ++ +++ E+ ++
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI----WRQKEKMHEQEKI 490
Query: 180 REELRQEWEAKQEKIKSEEIEI 201
R++ + W ++EK+ +E +I
Sbjct: 491 RKQEEKVWR-QEEKMHDQEEKI 511
Score = 50.1 bits (118), Expect = 3e-06
Identities = 40/186 (21%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
K +Q E++ + +++I E+ ++K E E + + + +QE
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Query: 80 LVKEREK---QLAKKEQSKELQMKLEKLREKERK-KEAKRKISSLSFTLEEEEEGGEEEE 135
+ +++EK Q ++Q +++ + EK+ ++E K +E + K+ + E+EE E+E
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
E +EEM +E+ + K + + + E+E ++RE+ +++ ++EKI
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ-KEKIREQEEKIW 595
Query: 196 SEEIEI 201
+E +I
Sbjct: 596 EQEEKI 601
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/178 (23%), Positives = 85/178 (47%), Gaps = 14/178 (7%)
Query: 17 LMKKREK---QREQMEQMKQRIAEENIMKSNIDKKFSAHYDAV---EAELKSSTVGLVTL 70
+ K+ EK Q E+M +++I E+ ++K + + E +++ +
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 71 NDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAK-----RKISSLSFTLE 125
+ +QE ++E+EK ++E+ +E + K+ + +EK R++E K KI ++
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 126 EEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREEL 183
E+EE E+EE +EE +E+ +R+ K + + R +EE+ +E L
Sbjct: 610 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL---RQQEEKMQEHQEHL 664
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/198 (24%), Positives = 96/198 (48%), Gaps = 31/198 (15%)
Query: 17 LMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAK 76
L +K +Q + EQ ++R EE I + ++ A E +++ + +
Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 441
Query: 77 QEALVKEREK--QLAKKEQSKELQMKLEKLREKER---------KKEAKRKISSLSFTLE 125
QE + E+EK + K+++ +E+ + EK+RE+E ++E RK +
Sbjct: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW--R 499
Query: 126 EEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEEN-RLREELR 184
+EE+ ++EE+ EE+M R+E ++++ ++ RE+EE R +EE+
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQE-------------EKIREQEEKIREQEEMM 546
Query: 185 QEWEAK----QEKIKSEE 198
QE E K +EK++ +E
Sbjct: 547 QEQEEKMGEQEEKMQEQE 564
Score = 47.4 bits (111), Expect = 2e-05
Identities = 40/131 (30%), Positives = 68/131 (51%), Gaps = 17/131 (12%)
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
+E + ++ EK ++E+ +E + K+ + E +KE K + +EE E+EE+
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--------RQEEMMWEKEEK 364
Query: 137 AAMYEEEM-EREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAK---- 190
EE M E+EE K R+L + ++ +EE ++RE E RQE EAK
Sbjct: 365 MRRLEEMMWEKEE---KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 421
Query: 191 QEKIKSEEIEI 201
+EKI+ +E +I
Sbjct: 422 EEKIREQEEKI 432
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/172 (20%), Positives = 78/172 (45%), Gaps = 13/172 (7%)
Query: 27 QMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREK 86
++EQ +A + ++ + DA+ EL +T+ D + K++ + +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI-----TDEELKEKNAKLQEKL 230
Query: 87 QLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMER 146
QL + E+S E+Q+ +++L+ K + AK + E + G E + +A + ++E
Sbjct: 231 QLVESEKS-EIQLNVKELKRKLER--AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 147 EEITTK-----KRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
E+ + + K+ + + + +EE+ R +EE +E E K +
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/222 (25%), Positives = 102/222 (45%), Gaps = 24/222 (10%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
+ ++R + E+++Q+ EE++ + + +A + E K++T T ++ EA
Sbjct: 33 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQVEGDDEA 88
Query: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEE--------EEEGG 131
ER LA++E+ ++ +++ ER+KE I+ S +L E E
Sbjct: 89 AFLER---LARREERRQKRLQ----EALERQKEFDPTITDASLSLPSRRMQNDTAENETT 141
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNP--DVDTSFLPDRDR-EEEENRLREELRQEWE 188
E+EE++ +E E EE T + KN D + + D+++ EEEE + + E +
Sbjct: 142 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 201
Query: 189 AKQEKIK--SEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQ 228
K EKIK E E S+ D VK + G M L+
Sbjct: 202 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 243
Score = 40.0 bits (92), Expect = 0.003
Identities = 49/197 (24%), Positives = 86/197 (43%), Gaps = 34/197 (17%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEA---------ELKSSTVGLVTLN 71
+EK+ E+ E+ K+ EN +K KK + V++ E+KS +T +
Sbjct: 182 KEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT-H 240
Query: 72 DMKAKQEALVKEREKQLAKKEQSK-----ELQMKLEKLREKERKKEA----KRKISSLSF 122
+K + + + ++++ E +LE+LR + + E+ K K
Sbjct: 241 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 300
Query: 123 TLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE 182
LE EE + EE + EEE +R + RKL + EEE+ RL+EE
Sbjct: 301 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLRE--------------EEEKRRLKEE 346
Query: 183 L-RQEWEAKQEKIKSEE 198
+ R+ EA +++ K E
Sbjct: 347 IERRRAEAAEKRQKMPE 363
Score = 34.3 bits (77), Expect = 0.16
Identities = 47/212 (22%), Positives = 88/212 (41%), Gaps = 22/212 (10%)
Query: 5 KGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSST 64
K SE+ + + +++ E + ++ R AEEN K + +K+ + E + K +
Sbjct: 143 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN-KKEDKEKE-----EEEEEKPKRGS 196
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQ------SKELQMKLEKLREKER---KKEAKR 115
+G + D K K++ KE K +++ S+ + KL+ E + +
Sbjct: 197 IGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRA 256
Query: 116 KISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR--- 172
+ + + E G+ EE E E EE K+K + R+
Sbjct: 257 SVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRK 316
Query: 173 ---EEEENRLREELRQEWEAKQEKIK-SEEIE 200
EEE+ R +EE ++ ++EK + EEIE
Sbjct: 317 VLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 348
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/222 (25%), Positives = 102/222 (45%), Gaps = 24/222 (10%)
Query: 20 KREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEA 79
+ ++R + E+++Q+ EE++ + + +A + E K++T T ++ EA
Sbjct: 39 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQVEGDDEA 94
Query: 80 LVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEE--------EEEGG 131
ER LA++E+ ++ +++ ER+KE I+ S +L E E
Sbjct: 95 AFLER---LARREERRQKRLQ----EALERQKEFDPTITDASLSLPSRRMQNDTAENETT 147
Query: 132 EEEEEAAMYEEEMEREEITTKKRKLGKNP--DVDTSFLPDRDR-EEEENRLREELRQEWE 188
E+EE++ +E E EE T + KN D + + D+++ EEEE + + E +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQ 207
Query: 189 AKQEKIK--SEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQ 228
K EKIK E E S+ D VK + G M L+
Sbjct: 208 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 249
Score = 40.0 bits (92), Expect = 0.003
Identities = 49/197 (24%), Positives = 86/197 (43%), Gaps = 34/197 (17%)
Query: 21 REKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEA---------ELKSSTVGLVTLN 71
+EK+ E+ E+ K+ EN +K KK + V++ E+KS +T +
Sbjct: 188 KEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT-H 246
Query: 72 DMKAKQEALVKEREKQLAKKEQSK-----ELQMKLEKLREKERKKEA----KRKISSLSF 122
+K + + + ++++ E +LE+LR + + E+ K K
Sbjct: 247 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 306
Query: 123 TLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE 182
LE EE + EE + EEE +R + RKL + EEE+ RL+EE
Sbjct: 307 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLRE--------------EEEKRRLKEE 352
Query: 183 L-RQEWEAKQEKIKSEE 198
+ R+ EA +++ K E
Sbjct: 353 IERRRAEAAEKRQKMPE 369
Score = 34.3 bits (77), Expect = 0.16
Identities = 47/212 (22%), Positives = 88/212 (41%), Gaps = 22/212 (10%)
Query: 5 KGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSST 64
K SE+ + + +++ E + ++ R AEEN K + +K+ + E + K +
Sbjct: 149 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN-KKEDKEKE-----EEEEEKPKRGS 202
Query: 65 VGLVTLNDMKAKQEALVKEREKQLAKKEQ------SKELQMKLEKLREKER---KKEAKR 115
+G + D K K++ KE K +++ S+ + KL+ E + +
Sbjct: 203 IGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRA 262
Query: 116 KISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDR--- 172
+ + + E G+ EE E E EE K+K + R+
Sbjct: 263 SVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRK 322
Query: 173 ---EEEENRLREELRQEWEAKQEKIK-SEEIE 200
EEE+ R +EE ++ ++EK + EEIE
Sbjct: 323 VLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 354
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 16/182 (8%)
Query: 19 KKREKQREQMEQM-KQRIAEENIMKSNIDKKFSAHYDAVEAE----LKSSTVGLVTLNDM 73
K RE+Q+EQ EQ ++R AEE + ++ SAH+ + + +K+S
Sbjct: 168 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 227
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKIS--SLSFTLEEEEEGG 131
+ + E L R+ +K + ++L L+ + + ERK + S S S + EEEEE
Sbjct: 228 RERFE-LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 286
Query: 132 EEEEEAAMYEE-EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE + EE E E EE ++ + G N + + + E EE+ ++ E +
Sbjct: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSE-------EASEQSAEEVSEEEMSEDEERE 339
Query: 191 QE 192
E
Sbjct: 340 NE 341
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/200 (19%), Positives = 90/200 (45%), Gaps = 14/200 (7%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
KKR K++E+ ++K+ N D + S E EL+ + + N +++
Sbjct: 20 KKRRKEQEEKAEIKRL--------KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED 71
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKLRE-KERKKEAKRKISSLSFTLEEEEEGGEEEEEA 137
++ E+ + + + + EK+ K+ K++ K K + + E + EE++
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDK 131
Query: 138 AMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSE 197
A E E ++ ++ + ++ + E E ++RE+ +++ E K+ + ++E
Sbjct: 132 ARREWERQKRREMAREHSRRERDRLEQL----ERKRERERKMREQQKEQREQKERERRAE 187
Query: 198 EI-EITFSYWDGSGHRRTVK 216
E + + + S H RT++
Sbjct: 188 ERRKEREARREVSAHHRTMR 207
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 16/182 (8%)
Query: 19 KKREKQREQMEQM-KQRIAEENIMKSNIDKKFSAHYDAVEAE----LKSSTVGLVTLNDM 73
K RE+Q+EQ EQ ++R AEE + ++ SAH+ + + +K+S
Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKIS--SLSFTLEEEEEGG 131
+ + E L R+ +K + ++L L+ + + ERK + S S S + EEEEE
Sbjct: 238 RERFE-LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 296
Query: 132 EEEEEAAMYEE-EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE + EE E E EE ++ + G N + + + E EE+ ++ E +
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSE-------EASEQSAEEVSEEEMSEDEERE 349
Query: 191 QE 192
E
Sbjct: 350 NE 351
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/206 (21%), Positives = 94/206 (45%), Gaps = 16/206 (7%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
KKR K++E+ ++K+ N D + S E EL+ + + N +++
Sbjct: 20 KKRRKEQEEKAEIKRL--------KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED 71
Query: 79 ALVKEREKQLAKKEQSKELQMKLEKL--REKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
++ E+ + + + + EK+ R+ E++KE R S + + E E
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHER 131
Query: 137 AAMYEEEME---REEITTKKRKLGKNPDV-DTSFLPDRDREEE-ENRLREELRQEWEAKQ 191
+ EE + RE K+R++ + + L +R+ E E ++RE+ +++ E K+
Sbjct: 132 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 191
Query: 192 EKIKSEEI-EITFSYWDGSGHRRTVK 216
+ ++EE + + + S H RT++
Sbjct: 192 RERRAEERRKEREARREVSAHHRTMR 217
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/137 (23%), Positives = 61/137 (44%), Gaps = 22/137 (16%)
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
+ A VKERE + ++++ +E Q K + E+++++E R+ S E+ E E E
Sbjct: 120 KHARVKEREHE--RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERER 177
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKS 196
+++ +RE+ +R+R EE R E R+E A ++
Sbjct: 178 KMREQQKEQREQ-------------------KERERRAEERRKEREARREVSAHHRTMRE 218
Query: 197 E-EIEITFSYWDGSGHR 212
+ ++ S+W S R
Sbjct: 219 DYSDKVKASHWSRSPPR 235
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 30/157 (19%)
Query: 70 LNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEE-- 127
L ++ K+E K RE+Q ++EQ + + E+ +E+ EA+R++S+ T+ E+
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKER----EARREVSAHHRTMREDYS 221
Query: 128 ----------------------EEGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPDVD 163
+G + +E M E ++ + ++I+ +RK
Sbjct: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 281
Query: 164 TSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
+ EEEE EE E +E+ + EE E
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 318
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 16/182 (8%)
Query: 19 KKREKQREQMEQM-KQRIAEENIMKSNIDKKFSAHYDAVEAE----LKSSTVGLVTLNDM 73
K RE+Q+EQ EQ ++R AEE + ++ SAH+ + + +K+S
Sbjct: 169 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 228
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKIS--SLSFTLEEEEEGG 131
+ + E L R+ +K + ++L L+ + + ERK + S S S + EEEEE
Sbjct: 229 RERFE-LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 287
Query: 132 EEEEEAAMYEE-EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE + EE E E EE ++ + G N + + + E EE+ ++ E +
Sbjct: 288 EEEEEGSTSEESEEEEEEEEEEEEETGSNSE-------EASEQSAEEVSEEEMSEDEERE 340
Query: 191 QE 192
E
Sbjct: 341 NE 342
Score = 45.1 bits (105), Expect = 9e-05
Identities = 48/214 (22%), Positives = 90/214 (42%), Gaps = 41/214 (19%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLN------- 71
KKR K++E+ ++K+ N D + S E EL+ + + N
Sbjct: 20 KKRRKEQEEKAEIKRL--------KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED 71
Query: 72 ---DMKAKQEALVKEREKQLAKKEQ------SKELQMKLEKLREKERKKEAKRKISSLSF 122
D + ++L + +Q+++KE+ K + K +++EKER+ E +++
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 123 TLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREE 182
E E ++ E A ER+ + +RK + + R+++E E R EE
Sbjct: 132 KARREWER-QKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRA-EE 189
Query: 183 LRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVK 216
R+E EA++E S H RT++
Sbjct: 190 RRKEREARREV---------------SAHHRTMR 208
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 16/182 (8%)
Query: 19 KKREKQREQMEQM-KQRIAEENIMKSNIDKKFSAHYDAVEAE----LKSSTVGLVTLNDM 73
K RE+Q+EQ EQ ++R AEE + ++ SAH+ + + +K+S
Sbjct: 178 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 237
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKIS--SLSFTLEEEEEGG 131
+ + E L R+ +K + ++L L+ + + ERK + S S S + EEEEE
Sbjct: 238 RERFE-LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 296
Query: 132 EEEEEAAMYEE-EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE + EE E E EE ++ + G N + + + E EE+ ++ E +
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSE-------EASEQSAEEVSEEEMSEDEERE 349
Query: 191 QE 192
E
Sbjct: 350 NE 351
Score = 49.7 bits (117), Expect = 4e-06
Identities = 49/225 (21%), Positives = 99/225 (44%), Gaps = 25/225 (11%)
Query: 19 KKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQE 78
KKR K++E+ ++K+ N D + S E EL+ + + N +++
Sbjct: 20 KKRRKEQEEKAEIKRL--------KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED 71
Query: 79 ALVK--EREKQLA-KKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
++ E + LA K Q + K+ ++++RK++ ++ E + EE++
Sbjct: 72 SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
+A E +R E+ + + + D F RDR E+ R RE R+ E ++E+ +
Sbjct: 132 KARREWERQKRREMAREHSRRERGNDGVCLF---RDRLEQLERKRERERKMREQQKEQRE 188
Query: 196 SEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240
+E E RR + RK ++ + +R+D+S+
Sbjct: 189 QKERE-----------RRAEERRKEREARREVSAHHRTMREDYSD 222
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/140 (22%), Positives = 67/140 (47%), Gaps = 11/140 (7%)
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
K K+ A VKE+E++ ++++ +E Q K + E+++++E R+ S E G +
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS-------RRERGNDG 158
Query: 134 EEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEK 193
++ + +E+ E ++ + + + +R+R EE R E R+E A
Sbjct: 159 ---VCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRT 215
Query: 194 IKSE-EIEITFSYWDGSGHR 212
++ + ++ S+W S R
Sbjct: 216 MREDYSDKVKASHWSRSPPR 235
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 53.9 bits (128), Expect = 2e-07
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 16/182 (8%)
Query: 19 KKREKQREQMEQM-KQRIAEENIMKSNIDKKFSAHYDAVEAE----LKSSTVGLVTLNDM 73
K RE+Q+EQ EQ ++R AEE + ++ SAH+ + + +K+S
Sbjct: 146 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 205
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKIS--SLSFTLEEEEEGG 131
+ + E L R+ +K + ++L L+ + + ERK + S S S + EEEEE
Sbjct: 206 RERFE-LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 264
Query: 132 EEEEEAAMYEE-EMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAK 190
EEEEE + EE E E EE ++ + G N + + + E EE+ ++ E +
Sbjct: 265 EEEEEGSTSEESEEEEEEEEEEEEETGSNSE-------EASEQSAEEVSEEEMSEDEERE 317
Query: 191 QE 192
E
Sbjct: 318 NE 319
Score = 37.7 bits (86), Expect = 0.015
Identities = 30/138 (21%), Positives = 58/138 (42%), Gaps = 2/138 (1%)
Query: 76 KQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEE 135
K E ++R + E K ++K EK RE ER+K + + E ++ E
Sbjct: 67 KDEKRKEKRRHRSHSAEGGKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMARE 125
Query: 136 EAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIK 195
+ + +E+ E ++ + + + +R+R EE R E R+E A ++
Sbjct: 126 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 185
Query: 196 SE-EIEITFSYWDGSGHR 212
+ ++ S+W S R
Sbjct: 186 EDYSDKVKASHWSRSPPR 203
Score = 36.2 bits (82), Expect = 0.043
Identities = 31/140 (22%), Positives = 60/140 (42%), Gaps = 40/140 (28%)
Query: 77 QEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEE 136
+ A VKE+E++ ++++ +E Q K + E+++++E R E E +
Sbjct: 86 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR------------EHSRRERDR 133
Query: 137 AAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKS 196
E + ERE +++K ++ ++E R EE R+E EA++E
Sbjct: 134 LEQLERKRERERKMREQQK-------------EQREQKERERRAEERRKEREARREV--- 177
Query: 197 EEIEITFSYWDGSGHRRTVK 216
S H RT++
Sbjct: 178 ------------SAHHRTMR 185
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 30/157 (19%)
Query: 70 LNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEE-- 127
L ++ K+E K RE+Q ++EQ + + E+ +E+ EA+R++S+ T+ E+
Sbjct: 134 LEQLERKRERERKMREQQKEQREQKERERRAEERRKER----EARREVSAHHRTMREDYS 189
Query: 128 ----------------------EEGGEEEEEAAMYEEEM--EREEITTKKRKLGKNPDVD 163
+G + +E M E ++ + ++I+ +RK
Sbjct: 190 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSS 249
Query: 164 TSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIE 200
+ EEEE EE E +E+ + EE E
Sbjct: 250 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 286
Score = 32.7 bits (73), Expect = 0.48
Identities = 18/74 (24%), Positives = 40/74 (54%), Gaps = 5/74 (6%)
Query: 74 KAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEE 133
+ +Q+ +E E+Q ++ + + + ++L + ERK+E +RK+ +++E+ ++
Sbjct: 104 REEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE-----QQKEQREQK 158
Query: 134 EEEAAMYEEEMERE 147
E E E ERE
Sbjct: 159 ERERRAEERRKERE 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,519,391
Number of Sequences: 37866
Number of extensions: 624376
Number of successful extensions: 21837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 551
Number of HSP's successfully gapped in prelim test: 1215
Number of HSP's that attempted gapping in prelim test: 6316
Number of HSP's gapped (non-prelim): 6814
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.