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Search of human proteins with 4758178
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform
a [Homo sapiens]
(645 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a... 1321 0.0
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform... 1269 0.0
gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform... 1217 0.0
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 1009 0.0
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 115 1e-25
gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens] 104 3e-22
gi|66267730 WD repeat domain 34 [Homo sapiens] 99 9e-21
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ... 94 3e-19
gi|217272887 WD repeat domain 63 [Homo sapiens] 57 4e-08
gi|155030242 WD repeat domain 60 [Homo sapiens] 55 2e-07
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 51 3e-06
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 51 3e-06
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 51 3e-06
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 51 3e-06
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 51 3e-06
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 50 5e-06
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 49 1e-05
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 49 1e-05
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 49 1e-05
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 49 1e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens] 48 3e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 47 7e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 47 7e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 7e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 7e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 7e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 7e-05
gi|148746195 trichohyalin [Homo sapiens] 46 1e-04
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 44 4e-04
gi|55741849 WD repeat domain 22 [Homo sapiens] 44 5e-04
>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
[Homo sapiens]
Length = 645
Score = 1321 bits (3418), Expect = 0.0
Identities = 645/645 (100%), Positives = 645/645 (100%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL
Sbjct: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
Query: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180
TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
Sbjct: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180
Query: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
Sbjct: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240
Query: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
Sbjct: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300
Query: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
Sbjct: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360
Query: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
Sbjct: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420
Query: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
Sbjct: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480
Query: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
Sbjct: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540
Query: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
Sbjct: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600
Query: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
[Homo sapiens]
Length = 628
Score = 1269 bits (3284), Expect = 0.0
Identities = 628/645 (97%), Positives = 628/645 (97%), Gaps = 17/645 (2%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
ALLQSIGISPEPPLV PTPMSPSSKSVSTPSEAGSQDSGDLGPL
Sbjct: 61 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL 103
Query: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180
TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
Sbjct: 104 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 163
Query: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
Sbjct: 164 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 223
Query: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
Sbjct: 224 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 283
Query: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
Sbjct: 284 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 343
Query: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
Sbjct: 344 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 403
Query: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
Sbjct: 404 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 463
Query: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
Sbjct: 464 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 523
Query: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
Sbjct: 524 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 583
Query: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 584 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 628
>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
[Homo sapiens]
Length = 608
Score = 1217 bits (3149), Expect = 0.0
Identities = 608/645 (94%), Positives = 608/645 (94%), Gaps = 37/645 (5%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
Query: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
ALLQSIGISPEPPLV PTPMSPSSKSVSTPSEAGSQDSGDLGPL
Sbjct: 61 ALLQSIGISPEPPLV-----------------PTPMSPSSKSVSTPSEAGSQDSGDLGPL 103
Query: 121 TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 180
TR RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
Sbjct: 104 TR--------------------RRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE 143
Query: 181 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 240
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
Sbjct: 144 EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV 203
Query: 241 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 300
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
Sbjct: 204 IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP 263
Query: 301 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 360
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
Sbjct: 264 ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT 323
Query: 361 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 420
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
Sbjct: 324 YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL 383
Query: 421 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 480
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
Sbjct: 384 DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF 443
Query: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 540
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
Sbjct: 444 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW 503
Query: 541 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 600
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
Sbjct: 504 SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG 563
Query: 601 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
Sbjct: 564 RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 608
>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
Length = 638
Score = 1009 bits (2609), Expect = 0.0
Identities = 492/651 (75%), Positives = 561/651 (86%), Gaps = 19/651 (2%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D QKKE PVQ++SDL++KRR
Sbjct: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58
Query: 58 ETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDL 117
E EALLQS+G++PE P+V + Y VP PMSPSSKSVSTPSEAGSQDSGD
Sbjct: 59 EAEALLQSMGLTPESPIV-----------FSEYWVPPPMSPSSKSVSTPSEAGSQDSGDG 107
Query: 118 GPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH 177
+RTL WDTDPSVLQL SDS+LGR KLG++K+TQVDF PRE+V+Y+KETQTP+
Sbjct: 108 AVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQ 167
Query: 178 QSEEDEEDEEMVESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFD 235
E++EED+++V K + E E KK E + APP ELTEEEKQQILHSEEFL FFD
Sbjct: 168 PKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFD 227
Query: 236 RTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDW 295
+ R++ERAL+E +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DW
Sbjct: 228 HSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDW 287
Query: 296 SLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNL 355
S QYPEL+VASYNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS FA+FHPNL
Sbjct: 288 SSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNL 347
Query: 356 VVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKM 415
VVGGTYSGQIVLWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+
Sbjct: 348 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 407
Query: 416 CSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAG 475
CSWSLDMLS PQ+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAG
Sbjct: 408 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 467
Query: 476 IGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYV 535
I E+FEGHQGP+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYV
Sbjct: 468 ISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYV 527
Query: 536 YDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAV 595
YDVMWSP HPALFACVDGMGRLDLWNLNNDTEVPTAS+++EG ALNRVRW +G+E+AV
Sbjct: 528 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAV 587
Query: 596 GDSEGRIWVYDVGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
GDSEG+I +YDVGE +AVP NDEW RF RTL EI ANRAD+EEE + A
Sbjct: 588 GDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
Length = 848
Score = 115 bits (289), Expect = 1e-25
Identities = 115/483 (23%), Positives = 206/483 (42%), Gaps = 72/483 (14%)
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEF---LIFFDRTI- 238
++D+ + S ++SE + + V A E E+ IL S++F L F +R +
Sbjct: 353 DQDQRLPGSTTEKNSETSSLMDIENVILAKIHEDEEDHSDAILKSDKFHQDLFFMERVLM 412
Query: 239 -RVIERALA--------------EDSDIFFDYSGRELEE---KDGDVQAGANLSFNRQFY 280
+ + LA E D+ E+EE K+ + + A S
Sbjct: 413 ENIFQPKLAAYRQLPVLKEPEPEEPEDVLESAKHEEVEEESKKEEEEEIHAEESTIPANL 472
Query: 281 DEHWS------KHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPE 334
+ WS K V+ + W+ P+L+ Y + + G+A W++K PE
Sbjct: 473 ERLWSFSCDLTKGLNVSSLAWNKTNPDLLAVGYGHF-GFKEQKRGLACCWSIK-NPMWPE 530
Query: 335 YVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYC 394
++ V +V F+ PNL+ G ++G I +++ RS+ PV + S H PV+
Sbjct: 531 RIYQSPYGVTAVDFSIGAPNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVWQ 590
Query: 395 VNVV-------GTQNAHNLITVSTDGKMCSWSL-------DML-------------STPQ 427
+ + G L+++S DG++ W + D++ +
Sbjct: 591 LQWIEQDRGTTGDGKREILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEKE 650
Query: 428 ESMELVYNKSKPVAVTGM--AFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQG 485
+ E + ++ P GM AF D N ++ G+EEG ++ C + + GH+G
Sbjct: 651 KKDEALISRQAP----GMCFAFHPKDTNIYLAGTEEGHIHK-CSCSYNEQYLDTYRGHKG 705
Query: 486 PVTGINCHMAVGPIDFSH-LFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVH 544
PV + + F H +F++ S DW V +W ++ KP SF VYDV WSP
Sbjct: 706 PVYKVTWN------PFCHDVFLSCSADWGVIIWQQENVKPSLSFYPATSVVYDVAWSPKS 759
Query: 545 PALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWV 604
+FA + R+++W+L+ T P + +A+ + VGDS+G++ V
Sbjct: 760 SYIFAAAN-ENRVEIWDLHISTLDPLIVNTANPGIKFTTILFAKQTDCLLVGDSDGQVSV 818
Query: 605 YDV 607
Y++
Sbjct: 819 YEL 821
>gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]
Length = 699
Score = 104 bits (259), Expect = 3e-22
Identities = 130/545 (23%), Positives = 230/545 (42%), Gaps = 71/545 (13%)
Query: 109 AGSQDSGDLGPLTRTLQWDTDPSVLQL----QSDSELGRRLHKLGVSKV----------- 153
AGSQ+S + T L+ D +P L+ Q+D K+ ++
Sbjct: 129 AGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKL 188
Query: 154 -TQVDFLPREVVSYSK-------ETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKK 205
Q +F R +Y+ +T+ P T+ S + E+ ++ V ELE Q+K
Sbjct: 189 TNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQ-WEIYDAYV---EELEKQEKT 244
Query: 206 QEVKEAPP-----------RELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDS--DIF 252
+E ++A R+LT E Q + LI + +++ER + +++ DI
Sbjct: 245 KEKEKAKTPVAKKSGKMAMRKLTSMESQT-----DDLIKLSQAAKIMERMVNQNTYDDIA 299
Query: 253 FDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNED 312
D+ + + Q G L + D+ +K VT + W+ +Y +L Y + D
Sbjct: 300 QDFKYYDDAADEYRDQVGTLLPLWKFQNDK--AKRLSVTALCWNPKYRDLFAVGYGSY-D 356
Query: 313 APHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS 372
+ G+ L++++K + PEY+F S VM + HP LV G Y G + +++ +
Sbjct: 357 FMKQSRGMLLLYSLK-NPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKK 415
Query: 373 HRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNL--ITVSTDGKMCSWSL--------DM 422
P + + H+ PV+ V NL +VS+DG++ SW+L D+
Sbjct: 416 PHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDV 475
Query: 423 LSTPQESMELVYNKS---KPVAV-TGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGE 478
+ E + PV T F F+VG+EEG +Y C + +
Sbjct: 476 IKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIY-KCSKSYSSQFLD 534
Query: 479 VFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDV 538
++ H V ++ + + +F++ S DWTVK+W P++ ++ N+ V DV
Sbjct: 535 TYDAHNMSVDTVSWNPY-----HTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNS-AVGDV 588
Query: 539 MWSPVHPALFACVDGMGRLDLWNLN-NDTEVPTASVAIEGASALNRVRWAQAGKEVAVGD 597
W+P +FA V G+ +++L N E + L V++ + VGD
Sbjct: 589 AWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGD 648
Query: 598 SEGRI 602
G I
Sbjct: 649 DRGHI 653
>gi|66267730 WD repeat domain 34 [Homo sapiens]
Length = 536
Score = 99.4 bits (246), Expect = 9e-21
Identities = 80/320 (25%), Positives = 146/320 (45%), Gaps = 41/320 (12%)
Query: 324 WNMKFKKTTPEY---VFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQR 380
WN+ + P+ V S+V+ + F P+ V GG YSG++++WD + R
Sbjct: 198 WNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWR 257
Query: 381 TPLSAAAHTHPVYCVNVV---GTQNAHNLITVSTDGKMCSW--------------SLDML 423
T L+ HT PV V + G + +++V+TDGK+ W +L M
Sbjct: 258 TGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQ 317
Query: 424 STPQESMELVYNKSKP-VAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV--- 479
P+ + + + + V T +AF + D F++G+E G +A + +
Sbjct: 318 QLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSS 377
Query: 480 ----------FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFE 529
F H GP+ ++C P +LF+++ D V L++ PL S +
Sbjct: 378 VPLRAPAQFTFSPHGGPIYSVSC----SPFH-RNLFLSAGTDGHVHLYSMLQAPPLTSLQ 432
Query: 530 DNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASV-AIEGASALNRVRW-A 587
+ Y++ V WSPV P +FA G G + L++L ++ PT + + S + + + +
Sbjct: 433 LSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNS 492
Query: 588 QAGKEVAVGDSEGRIWVYDV 607
Q + +A GD++G + V+ +
Sbjct: 493 QQTQLLAAGDAQGTVKVWQL 512
>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
Length = 605
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/488 (21%), Positives = 201/488 (41%), Gaps = 37/488 (7%)
Query: 139 SELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH-QSEEDEEDEEMVESKVGQDS 197
SE G++ + +D +P ++ + P+ T Q + E + ++
Sbjct: 12 SEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMET 71
Query: 198 ELENQDKKQEVKEAPPREL--TEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDI---- 251
N + K+ P EL T ++++ E ++ + ++E + +++ I
Sbjct: 72 RGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYE 131
Query: 252 --FFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYN- 308
F D E+ E+D + F D K R T + W + +Y+
Sbjct: 132 EYFNDEEAMEVMEEDPSAKT------INVFRDPQEIK-RAATHLSWHPDGNRKLAVAYSC 184
Query: 309 -NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL 367
+ + AP + +W+++ PE S ++++ F ++++GG Y+GQI
Sbjct: 185 LDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIAC 243
Query: 368 WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQ 427
WD R + + V ++H PVY + ++ + STDG++ W + +S P
Sbjct: 244 WDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPT 301
Query: 428 ESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV---F 480
E + L K + + + F + F+VG+E+G V + C +K ++ F
Sbjct: 302 EVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTF 360
Query: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDVM 539
GH GP+ + + + F+T DWT ++W+ + + + Y+ D
Sbjct: 361 PGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAA 414
Query: 540 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSE 599
WSPV P +F G LD+W+ + PT S+ + AL +R G +A G
Sbjct: 415 WSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQL 473
Query: 600 GRIWVYDV 607
G + +V
Sbjct: 474 GTTTLLEV 481
>gi|217272887 WD repeat domain 63 [Homo sapiens]
Length = 891
Score = 57.4 bits (137), Expect = 4e-08
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 21/199 (10%)
Query: 193 VGQDSELENQDKKQEVKEAP----PRELTEEEKQQILHSEEFLIFFDRTIRVIERALAED 248
+ Q ++ Q K K A PRE +EEEK+ + S+ + F + +E AL ++
Sbjct: 235 IPQIKDISTQTKWTYPKNATTQYYPREFSEEEKETLKQSKPLVDFLNNASISVEIALQQN 294
Query: 249 S--DIFFDYSGRELEEKDGDV--QAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMV 304
+ F D + L E++G + +L + F D H +++TC+ W L+
Sbjct: 295 EIMNTFID-DWKYLAEEEGTFGDKTDTHLKEYQSFTDLHSPTEKMITCVSWHPTIYGLIA 353
Query: 305 ASYN---NNEDAPH-------EPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPN 354
S + ED H +P + L W+ P+ + + F PN
Sbjct: 354 VSVAVRLSFEDRVHFSGKLLLQPS-LILFWSFS-DPIHPQLMLESPDDIFCFKFCPSDPN 411
Query: 355 LVVGGTYSGQIVLWDNRSH 373
++ GG +GQIV+WD +H
Sbjct: 412 IIAGGCINGQIVMWDITAH 430
Score = 30.0 bits (66), Expect = 6.9
Identities = 12/32 (37%), Positives = 22/32 (68%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKK 43
ER+ + L + + KK +E+E+K+ E +M +KK
Sbjct: 812 EREVKHLEYVEQRKKIREQEKKEMELEMAKKK 843
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 55.5 bits (132), Expect = 2e-07
Identities = 70/350 (20%), Positives = 130/350 (37%), Gaps = 80/350 (22%)
Query: 320 VALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRS------- 372
V VW++ ++ + P+ V C+S V C + L+ GT G +V+WD R
Sbjct: 677 VLCVWDI-WQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGSVVVWDLREDSRLHYS 735
Query: 373 ------------------------HRRTPVQRT-PLSAAAHTHPVYCVNVVGTQN----- 402
+ R+P+Q P+S + H + ++ TQ
Sbjct: 736 VTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQSFVLSPFSTQEEMSGL 795
Query: 403 AHNLITVSTDGKMCSWSL-------------DMLSTPQESMELVYNKSKPVA-------- 441
+ ++ ++ G + W + D+ P ++LV++ +
Sbjct: 796 SFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVHSALIQLGDSLSHKGN 855
Query: 442 -------VTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHM 494
+ F D N+F++G++ G + R + ++F+ Q + +
Sbjct: 856 EFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVA-PKLFKPQQHGIRPVK--- 911
Query: 495 AVGPIDFSH----LFVTSSFDWTVKLWTTKHNKPLYSFEDNADY--VYDVMWSPVHPALF 548
V IDFS +F+ D +++L PL ++ + D V + WSP PA+F
Sbjct: 912 -VNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVF 970
Query: 549 ACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDS 598
D + +W+L P VA + S V A G+ G S
Sbjct: 971 LVQDDTSNIYIWDLLQSDLGP---VAKQQVSPNRLVAMAAVGEPEKAGGS 1017
Score = 33.5 bits (75), Expect = 0.62
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 22 REEKKRKEEE-RKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISP 70
+EE+K +E++ RK+ E D+ + KEP D D D + R+ A + + SP
Sbjct: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESP 80
>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
Length = 1205
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 550 CVDGMGRLDLWNL 562
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 550 CVDGMGRLDLWNL 562
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
Length = 1106
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 550 CVDGMGRLDLWNL 562
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
Length = 1181
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 550 CVDGMGRLDLWNL 562
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 51.2 bits (121), Expect = 3e-06
Identities = 61/313 (19%), Positives = 117/313 (37%), Gaps = 37/313 (11%)
Query: 259 ELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPD 318
+L + D+++ A S + +++ W ++ MD +++A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYK----MDSKGDVSGVLIAGGENGNIILYDPS 104
Query: 319 GVA-----LVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSH 373
+ +V K T P V ++ F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 374 RRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLITVSTDGKMCSWSLDMLSTPQESME 431
TP++ A T P ++ + Q H L + S G+ W L E +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 432 LVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIG--EVFEGHQGPVTG 489
V + S + +G+A+ V+ SE+ + + V E H +
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILA 265
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
I MA L ++ D + + LY N + +D+ W P +PA+ +
Sbjct: 266 IAWSMAD-----PELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLS 320
Query: 550 CVDGMGRLDLWNL 562
GR+ ++++
Sbjct: 321 AASFDGRISVYSI 333
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 50.4 bits (119), Expect = 5e-06
Identities = 57/243 (23%), Positives = 104/243 (42%), Gaps = 25/243 (10%)
Query: 352 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 407
+P+++ T S ++++D H P L H Y ++ + H L+
Sbjct: 135 NPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGH-LL 193
Query: 408 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFV--------VGS 459
+ S D +C W D+ + P+E ++V K+ TG + DV + V
Sbjct: 194 SASDDHTVCLW--DINAGPKEG-KIVDAKA---IFTGHSAVVEDVAWHLLHESLFGSVAD 247
Query: 460 EEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTT 519
++ + R + + + + H V NC ++ P + T S D TV LW
Sbjct: 248 DQKLMIWDTRSNTTSKPSHLVDAHTAEV---NC-LSFNPYS-EFILATGSADKTVALWDL 302
Query: 520 KHNK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGA 578
++ K L++FE + D ++ V WSP + + A RL++W+L+ E +A A +G
Sbjct: 303 RNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGP 362
Query: 579 SAL 581
L
Sbjct: 363 PEL 365
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 474 AGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNAD 533
AG +V++ H V ++ G L V+ S+D TVKLW K L +F +
Sbjct: 101 AGPLQVYKEHAQEVYSVDWSQTRG----EQLVVSGSWDQTVKLWDPTVGKSLCTFRGHES 156
Query: 534 YVYDVMWSPVHPALFACVDGMGRLDLWNL 562
+Y +WSP P FA G L +W++
Sbjct: 157 IIYSTIWSPHIPGCFASASGDQTLRIWDV 185
Score = 30.8 bits (68), Expect = 4.0
Identities = 41/168 (24%), Positives = 61/168 (36%), Gaps = 39/168 (23%)
Query: 456 VVGSEEGTVYTACRHGSKAGIGEVFEG--------HQGPVTGINCHMAVGPIDFSHLFVT 507
V G + T RHG A G H G + G + + P D + L +
Sbjct: 4 VCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYG-IAGCGTLLILDP-DEAGLRLF 61
Query: 508 SSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTE 567
SFDW D ++DV WS + + G G L LW DT
Sbjct: 62 RSFDWN-------------------DGLFDVTWSENNEHVLITCSGDGSLQLW----DTA 98
Query: 568 VPTASVAI--EGASALNRVRWAQA-GKEVAVG---DSEGRIWVYDVGE 609
+ + E A + V W+Q G+++ V D ++W VG+
Sbjct: 99 KAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGK 146
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 352 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 407
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 101 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 159
Query: 408 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 467
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 160 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 210
Query: 468 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 521
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 211 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 270
Query: 522 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 580
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 271 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 330
Query: 581 L 581
L
Sbjct: 331 L 331
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 352 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 407
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 135 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 193
Query: 408 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 467
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 194 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 244
Query: 468 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 521
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 245 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 304
Query: 522 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 580
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 305 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 364
Query: 581 L 581
L
Sbjct: 365 L 365
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/241 (22%), Positives = 100/241 (41%), Gaps = 21/241 (8%)
Query: 352 HPNLVVGGTYSGQIVLWDNRSHRRTPVQ----RTPLSAAAHTHPVYCVNVVGTQNAHNLI 407
+P ++ T S ++++D H P L H Y ++ + H L+
Sbjct: 136 NPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGH-LL 194
Query: 408 TVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA 467
+ S D +C W D+ + P+E + TG DV+ ++ +++ +
Sbjct: 195 SASDDHTICLW--DISAVPKEGKVV----DAKTIFTGHTAVVEDVSWHLLHE---SLFGS 245
Query: 468 CRHGSKAGIGEVFEGHQG-PVTGINCHMA-VGPIDFS----HLFVTSSFDWTVKLWTTKH 521
K I + + P ++ H A V + F+ + T S D TV LW ++
Sbjct: 246 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 305
Query: 522 NK-PLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASA 580
K L+SFE + D ++ V WSP + + A RL++W+L+ E + A +G
Sbjct: 306 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 365
Query: 581 L 581
L
Sbjct: 366 L 366
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/181 (24%), Positives = 81/181 (44%), Gaps = 19/181 (10%)
Query: 430 MELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTG 489
++++Y S PV G +F + D N + SE+GTV +G ++GH PV
Sbjct: 536 LKILYGHSGPVY--GASF-SPDRNYLLSSSEDGTVRLWSLQTFTCLVG--YKGHNYPVWD 590
Query: 490 INCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFA 549
+ + FV+ D +LW T H +PL F A ++ DV + HP
Sbjct: 591 TQFS------PYGYYFVSGGHDRVARLWATDHYQPLRIF---AGHLADVNCTRFHPNSNY 641
Query: 550 CVDGMG--RLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDV 607
G + LW++ N V + ++ + ++ G+ +A G ++GR+ ++D+
Sbjct: 642 VATGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI 698
Query: 608 G 608
G
Sbjct: 699 G 699
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 154 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 209
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 210 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 243
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 244 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 301
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 302 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 339
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 219
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 220 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 253
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 254 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 311
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 312 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 349
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 155 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 210
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 211 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 244
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 245 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 302
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 303 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 340
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 132 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 187
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 188 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 221
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 222 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 279
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 280 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 317
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 121 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 176
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 177 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 210
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 211 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 268
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 269 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 306
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 46.6 bits (109), Expect = 7e-05
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 38/221 (17%)
Query: 6 DLKAELERKKQRLAQIREEKK--RKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALL 63
D +LERK++R ++RE++K R+++ER+++ + ++++E ++ S R RE
Sbjct: 166 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED---- 221
Query: 64 QSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRT 123
Y S S+S P + P+
Sbjct: 222 --------------------------YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 255
Query: 124 LQWDTDP-SVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEED 182
+ D S LQ SDSE R+ S E +E + + +SEE+
Sbjct: 256 KMEERDLLSDLQDISDSE--RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE 313
Query: 183 EEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQ 223
EE+EE E + G +SE ++ +EV E E++E+E+++
Sbjct: 314 EEEEEEEEEETGSNSEEASEQSAEEVSE---EEMSEDEERE 351
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 45/264 (17%)
Query: 1 MSDKSDLKAELERK---KQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRR 57
+ ++ L+ E RK +++L Q REE++ +ER +K + +Q+ + DRK R
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR----RQERDRKFR 1504
Query: 58 ETEALLQSIGISPEPPLV---QPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDS 114
E E Q PE + Q LH K + + Q+
Sbjct: 1505 EQELRSQ----EPERKFLEEEQQLH---------------RQQRQRKFLQEEQQLRRQER 1545
Query: 115 GDLGPLTRTLQWDTDPSVLQLQSDSELGR----RLHKLGVSKVTQVD----FLPREVVSY 166
G R ++ + + Q + + +L R R +L KV + + F+ E
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR 1605
Query: 167 SKETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILH 226
+E Q L + + EDE++++ + ++ +L Q++ ++ E P+ +E +QQ+ H
Sbjct: 1606 RQEGQQQLRQERDRKFREDEQLLQER--EEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 227 SEEFLIFFDRTIRVIERALAEDSD 250
DR R E+ L E +
Sbjct: 1664 DR------DRKFREEEQLLQEGEE 1681
Score = 35.8 bits (81), Expect = 0.13
Identities = 51/231 (22%), Positives = 99/231 (42%), Gaps = 33/231 (14%)
Query: 10 ELERKKQRLAQIREEKKRKEE-ERK-KKEADMQQKKEPVQDD-------SDLDRKRRETE 60
EL++++++L + EK+R++E ER+ ++E ++QQ++E + + +L+R+ RE E
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 61 ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL 120
L Q E L++ Y + + E D
Sbjct: 1175 ELQQE-----EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD------- 1222
Query: 121 TRTLQWDTDPSVLQLQSDSEL---GRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH 177
L+W +P D+++ GR + + +Q+ R+ S++ L
Sbjct: 1223 ---LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL----RD--RQSQQDLQHLLGE 1273
Query: 178 QSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSE 228
Q E D E E + + E Q +++E KEA R+ +E++Q+L E
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Score = 35.4 bits (80), Expect = 0.16
Identities = 18/55 (32%), Positives = 37/55 (67%), Gaps = 6/55 (10%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
+LER++Q+ A+ R+ K ++E++ ++E + +++++ + DRK RE E LLQ
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ------ETDRKFREEEQLLQ 1346
Score = 34.7 bits (78), Expect = 0.28
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 3/59 (5%)
Query: 12 ERKKQRLAQIREEKKRKEE-ERKKKEAD--MQQKKEPVQDDSDLDRKRRETEALLQSIG 67
+ +KQ L + REEK+R++E +RK +E + +Q+++E + DRK RE E Q G
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Score = 34.3 bits (77), Expect = 0.37
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 7/62 (11%)
Query: 10 ELERKKQRLAQIREEKKRK-------EEERKKKEADMQQKKEPVQDDSDLDRKRRETEAL 62
E ER+KQ+L + +EE++R+ EE R+++E QQ + ++ + KR+E E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 63 LQ 64
LQ
Sbjct: 528 LQ 529
Score = 34.3 bits (77), Expect = 0.37
Identities = 17/50 (34%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 12 ERKKQRLAQIREEKKRKEEERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
+ ++Q L + RE ++R+E ER+ +KE ++QQ++E + + R+R+E E
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
Score = 33.9 bits (76), Expect = 0.48
Identities = 17/58 (29%), Positives = 39/58 (67%), Gaps = 5/58 (8%)
Query: 3 DKSDLKAELERKKQRLAQIREEKK---RKEEERKKKEADMQQKKEPVQDDSDLDRKRR 57
++ + K E ER++QRL + +EE++ ++EEE ++ E +++K+ ++ D + +R+ R
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHE--QERRKQQLKRDQEEERRER 487
Score = 33.9 bits (76), Expect = 0.48
Identities = 15/53 (28%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 10 ELERKKQRLAQIREEKKRKEEERK--KKEADMQQKKEPVQDDSDLDRKRRETE 60
+L++++++L + EK+R++E + +K+ +QQK+E + + R+R+E E
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Score = 33.9 bits (76), Expect = 0.48
Identities = 17/53 (32%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKK--KEADMQQKKEPVQDDSDLDRKRRETE 60
+L++K+++L EK+R++E KK +E ++QQ++E + + R+R+E E
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/53 (35%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
ER+K+RL Q RE + R+EEE +++E + ++ + +L+R+ R+ E L Q
Sbjct: 1037 EREKRRL-QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/53 (35%), Positives = 32/53 (60%), Gaps = 5/53 (9%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
ER++Q+L + ++K +EEE+ ++E + QQ + + DRK RE E L Q
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLR-----SQESDRKFREEEQLRQ 1805
Score = 33.1 bits (74), Expect = 0.81
Identities = 18/55 (32%), Positives = 38/55 (69%), Gaps = 2/55 (3%)
Query: 8 KAELERKKQRLAQIREEKKR-KEEERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
K EL++++++L + EK+R +E ER+ ++E ++QQ++E + + R+R+E E
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Score = 33.1 bits (74), Expect = 0.81
Identities = 16/49 (32%), Positives = 30/49 (61%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRE 58
+LE ++QRL Q R+ + R EE+ +E ++++E Q++ R+ RE
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Score = 32.7 bits (73), Expect = 1.1
Identities = 16/55 (29%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKEADM--QQKKEPVQDDSDLDRKRRETE 60
+ E E+++QRL + ++ ++++EEER++++ + QQ++ Q++ + RRE E
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Score = 32.7 bits (73), Expect = 1.1
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 4 KSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDR-KRRETEAL 62
+ + + E ER++QRL RE+++R+++ K++E QQ+ + Q++ R KR E E L
Sbjct: 553 EEEKRLEQERREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 63 LQ 64
Q
Sbjct: 611 EQ 612
Score = 32.7 bits (73), Expect = 1.1
Identities = 14/52 (26%), Positives = 37/52 (71%), Gaps = 1/52 (1%)
Query: 7 LKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRE 58
LK+E E++++R Q+R E++ + E+R K+E + ++ ++ ++ + + +R+ +E
Sbjct: 634 LKSE-EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Score = 32.3 bits (72), Expect = 1.4
Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 8/61 (13%)
Query: 12 ERKKQRLAQIREEKKRKEEERK-KKEADMQQKKEPVQDDSDLDRKR-------RETEALL 63
+ ++Q L + RE+++R+E ER+ +K+ +QQK+E + + R+R RE E L
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 64 Q 64
Q
Sbjct: 998 Q 998
Score = 32.0 bits (71), Expect = 1.8
Identities = 41/223 (18%), Positives = 94/223 (42%), Gaps = 36/223 (16%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPE 71
E++++R Q+R E++ + E+R K++ + ++ ++ ++ + L R++ E Q + E
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE--QLLKREEE 555
Query: 72 PPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPS 131
L Q + E Q L+ + +
Sbjct: 556 KRLEQERR-------------------EQRLKREQEERRDQ----------LLKREEERR 586
Query: 132 VLQLQSDSE--LGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMV 189
+L+ + E L +RL + V ++ Q + + + E + +SEE EE +
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 190 ---ESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEE 229
E + ++ L+ +++++ +++ RE EE ++Q L EE
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Score = 32.0 bits (71), Expect = 1.8
Identities = 19/58 (32%), Positives = 37/58 (63%), Gaps = 3/58 (5%)
Query: 4 KSDLKAELERKKQRLAQIREEKKRKEEERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
+ L E E + QR + RE+++R+E+ER+ ++E +QQ++E + + R+R+E E
Sbjct: 902 EQQLLQEEEEELQR--EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Score = 31.6 bits (70), Expect = 2.4
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQ-----DDSDLDRK 55
+ + L+ E E ++++L + REE+KR E+ER+++ +Q++ Q ++ R
Sbjct: 532 LRSEQQLRREQEERREQLLK-REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 56 RRETEALLQ 64
+RE E L+
Sbjct: 591 KREQEERLE 599
Score = 31.6 bits (70), Expect = 2.4
Identities = 17/53 (32%), Positives = 37/53 (69%), Gaps = 2/53 (3%)
Query: 10 ELERKKQRLAQIREEKKRK-EEERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
EL++++++L + EK+R+ E ER+ ++E ++QQ++E + + R+R+E E
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Score = 31.2 bits (69), Expect = 3.1
Identities = 16/58 (27%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 6 DLKAELERKKQRLAQIREEKKRKEEERK---KKEADMQQKKEPVQDDSDLDRKRRETE 60
D + E R +QR EE++ + EE+K +++ Q++K+ ++++ + R+R+ET+
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD 1335
Score = 30.8 bits (68), Expect = 4.0
Identities = 21/99 (21%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 134 QLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVESKV 193
+LQ + E R+L + + + Q + ++ + ++ + + E+ EE E E +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 194 GQDSELENQ---DKKQEVKEAPPRELTEEEKQQILHSEE 229
Q+ E Q ++++ ++ RE EE ++Q L E+
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Score = 30.8 bits (68), Expect = 4.0
Identities = 19/54 (35%), Positives = 34/54 (62%), Gaps = 4/54 (7%)
Query: 7 LKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
LK E ER++QRL RE+++R E+ K++E + +++E + + L R+ E E
Sbjct: 579 LKREEERRQQRLK--REQEERLEQRLKREEVERLEQEE--RREQRLKREEPEEE 628
Score = 30.4 bits (67), Expect = 5.3
Identities = 13/50 (26%), Positives = 35/50 (70%), Gaps = 4/50 (8%)
Query: 12 ERKKQRLAQIREEKK----RKEEERKKKEADMQQKKEPVQDDSDLDRKRR 57
ER++Q+L + +EE++ R+E+E +++E +++++E + + L R+++
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 30.4 bits (67), Expect = 5.3
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 9/65 (13%)
Query: 8 KAELERKKQRLAQIREEKKRKE---EERKKKEADMQQKKEPVQDDSDL-----DRKRRET 59
+ ELERK + Q+R+E ++++ +ER +K + +Q + P +++ L DRK RE
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR-PEREEQQLRRQERDRKFREE 1776
Query: 60 EALLQ 64
E L Q
Sbjct: 1777 EQLRQ 1781
Score = 30.4 bits (67), Expect = 5.3
Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 2/34 (5%)
Query: 13 RKKQRLAQIREEKKRKEEERKKKEADM--QQKKE 44
R++Q L Q E+K+R+E ERK +E + QQK+E
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 30.0 bits (66), Expect = 6.9
Identities = 14/54 (25%), Positives = 33/54 (61%)
Query: 13 RKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSI 66
RK++ + + EEK ++EE ++++E ++++ + +L R+R+E E Q +
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Score = 30.0 bits (66), Expect = 6.9
Identities = 15/53 (28%), Positives = 32/53 (60%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
E ++R Q RE+K R+EEE +++E + +++ + + +R+ R+ + L Q
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 3 DKSDLKAELERKKQRLAQIREEKK--RKEEERK--KKEADMQQKKEPVQDDSDLDRKRRE 58
D+ + EL ++Q + EE++ R+E ERK K+E ++ ++ Q D DRK RE
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 59 TEALL 63
E L
Sbjct: 1419 EEQQL 1423
Score = 30.0 bits (66), Expect = 6.9
Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 9/55 (16%)
Query: 13 RKKQRLAQIREEK---KRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQ 64
R+++R + REE+ +R+E ERK + + Q +++ +L+RK RE E L Q
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ------ELERKFREEEQLRQ 1733
Score = 29.6 bits (65), Expect = 9.0
Identities = 11/47 (23%), Positives = 32/47 (68%)
Query: 12 ERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRE 58
E++ +R Q+R E++ + E++ ++E +++++E + + +++RRE
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Score = 29.6 bits (65), Expect = 9.0
Identities = 13/62 (20%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 10 ELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGIS 69
E ++++QR EEK+++ +R+++E ++Q ++++ L R+ R + + G+
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQF----LEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 70 PE 71
+
Sbjct: 858 ED 859
Score = 29.6 bits (65), Expect = 9.0
Identities = 16/53 (30%), Positives = 37/53 (69%), Gaps = 2/53 (3%)
Query: 10 ELERKKQRLAQIREEKKRKEE-ERK-KKEADMQQKKEPVQDDSDLDRKRRETE 60
EL++++++L + EK+R++E ER+ +K+ ++QQ++E + + R+ +E E
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Score = 29.6 bits (65), Expect = 9.0
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 11 LERKKQRLAQIREEKKRKEEERKKKEAD--MQQKKEPVQDDSDLDRKRRETEALLQ 64
LE + Q Q RE++ R + +RK +E + +Q+ +E + DRK RE E L+
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 44.3 bits (103), Expect = 4e-04
Identities = 56/219 (25%), Positives = 98/219 (44%), Gaps = 15/219 (6%)
Query: 12 ERKKQRLAQIREEKKRK----EEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIG 67
E++K+ L + REE K+K +ER++KE + +K+ +D +L K L+ +
Sbjct: 541 EQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPE 600
Query: 68 ISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWD 127
P + + +CY L+P P + +VS EA S D G L R L
Sbjct: 601 GLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPIT-AVSL-MEALSADKGGFLYLNRVL--- 655
Query: 128 TDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEE 187
+LQ E+ +LG+ K++++ V + + E + ++
Sbjct: 656 --VILLQTLLQDEIAEDYGELGM-KLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDD 712
Query: 188 MVESKVGQDSELENQD-KKQEVKEAPPRELTEEEKQQIL 225
+S +D+E++++ +K E E ELT EEK QIL
Sbjct: 713 NKDSAAFEDNEVQDEFLEKLETSEF--FELTSEEKLQIL 749
Score = 31.2 bits (69), Expect = 3.1
Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE 60
M + + AEL K+RLA ++EE +K E++K++ + KE + ++ L + R+ E
Sbjct: 766 METRQQMSAELW--KERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKE 823
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/182 (21%), Positives = 81/182 (44%), Gaps = 32/182 (17%)
Query: 394 CVNVVGTQNAHN--LITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTG------- 444
CVN + N L++ D ++ W ++ + ++++ KP+ + G
Sbjct: 55 CVNAIEFSNNGGQWLVSGGDDRRVLLWHME---------QAIHSRVKPIQLKGEHHSNIF 105
Query: 445 -MAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSH 503
+AF +G+ F G++E + +VF H+ V G++ V P++ +
Sbjct: 106 CLAFNSGNTKVFSGGNDEQVILHDVESSETL---DVF-AHEDAVYGLS----VSPVN-DN 156
Query: 504 LFVTSSFDWTVKLWTTK---HNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLW 560
+F +SS D V +W + H +P + + + VM++PV P L A + + LW
Sbjct: 157 IFASSSDDGRVLIWDIRESPHGEP-FCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLW 215
Query: 561 NL 562
++
Sbjct: 216 DI 217
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,663,916
Number of Sequences: 37866
Number of extensions: 1337115
Number of successful extensions: 18901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 397
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 10087
Number of HSP's gapped (non-prelim): 6928
length of query: 645
length of database: 18,247,518
effective HSP length: 109
effective length of query: 536
effective length of database: 14,120,124
effective search space: 7568386464
effective search space used: 7568386464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.