Guide to the Human Genome
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Search of human proteins with 4757926

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4757926 RNA binding motif protein 39 isoform b [Homo
sapiens]
         (524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]     1025   0.0  
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]    1018   0.0  
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]    474   e-134
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]    461   e-130
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]    437   e-122
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...   102   1e-21
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...   102   1e-21
gi|7706607 LEM domain containing 3 [Homo sapiens]                     102   1e-21
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...   100   3e-21
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor...    92   2e-18
gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo...    91   3e-18
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    87   3e-17
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ...    83   5e-16
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ...    83   5e-16
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    83   5e-16
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    83   5e-16
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo...    83   7e-16
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    81   3e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    81   3e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    81   3e-15
gi|20373175 musashi 2 isoform a [Homo sapiens]                         80   3e-15
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     80   6e-15
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                     79   8e-15
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                79   8e-15
gi|25121993 musashi 2 isoform b [Homo sapiens]                         79   1e-14
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     79   1e-14
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]              78   2e-14
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    77   5e-14
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      76   7e-14
gi|52426743 cisplatin resistance-associated overexpressed protei...    76   9e-14

>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
          Length = 524

 Score = 1025 bits (2649), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
           MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD
Sbjct: 1   MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60

Query: 61  RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
           RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL
Sbjct: 61  RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120

Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
           SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR
Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180

Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
           DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN
Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240

Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
           NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD
Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300

Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
           SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM
Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360

Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF 420
           ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF
Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF 420

Query: 421 QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA 480
           QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA
Sbjct: 421 QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA 480

Query: 481 AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
           AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR
Sbjct: 481 AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524


>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
          Length = 530

 Score = 1018 bits (2632), Expect = 0.0
 Identities = 524/530 (98%), Positives = 524/530 (98%), Gaps = 6/530 (1%)

Query: 1   MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
           MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD
Sbjct: 1   MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60

Query: 61  RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
           RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL
Sbjct: 61  RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120

Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
           SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR
Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180

Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
           DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN
Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240

Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
           NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD
Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300

Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
           SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM
Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360

Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA------DLQTRLSQQTEASALAAAASVQP 414
           ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA      DLQTRLSQQTEASALAAAASVQP
Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP 420

Query: 415 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 474
           LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS
Sbjct: 421 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 480

Query: 475 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
           IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR
Sbjct: 481 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530


>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
          Length = 439

 Score =  474 bits (1220), Expect = e-134
 Identities = 274/465 (58%), Positives = 327/465 (70%), Gaps = 71/465 (15%)

Query: 4   DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40
           DI IEAMLEAPYKK+E++                S++N   E S         K+K+S+S
Sbjct: 7   DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66

Query: 41  RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95
            ++S +RKRS+S++R R R R  R +S  R+ R RSRS +RR  S SRSRD R   R  Y
Sbjct: 67  HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126

Query: 96  RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155
           RSP                   +    R   SKSP  ++KSPVREP+DNL+PEERDARTV
Sbjct: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168

Query: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215
           FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG
Sbjct: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228

Query: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275
           QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+
Sbjct: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288

Query: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335
           I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D  + 
Sbjct: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348

Query: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385
            +F D D+     +DLG+  GR QLMA+LAEG G+Q+P  A           ALQ++G++
Sbjct: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404

Query: 386 AFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 430
             GA+             +AL A +    LA+QCFQLS++F PQT
Sbjct: 405 PLGAL-----------NPAALTALSPALNLASQCFQLSSLFTPQT 438


>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
          Length = 423

 Score =  461 bits (1186), Expect = e-130
 Identities = 266/449 (59%), Positives = 314/449 (69%), Gaps = 55/449 (12%)

Query: 4   DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60
           DI IEAMLEAPYKK+E++       ++       S S S +     S   ++  R R RD
Sbjct: 7   DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66

Query: 61  RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111
           R R++ S+SR      R RSRS +RR  S SRSRD R   R  YRSP             
Sbjct: 67  RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113

Query: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171
                 +    R   SKSP  ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+
Sbjct: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168

Query: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231
           FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE
Sbjct: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228

Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
           KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK
Sbjct: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288

Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351
           GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D  +  +F D D+     +DL
Sbjct: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344

Query: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQT 401
           G+  GR QLMA+LAEG G+Q+P  A           ALQ++G++  GA+           
Sbjct: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393

Query: 402 EASALAAAASVQPLATQCFQLSNMFNPQT 430
             +AL A +    LA+QCFQLS++F PQT
Sbjct: 394 NPAALTALSPALNLASQCFQLSSLFTPQT 422


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score =  437 bits (1123), Expect = e-122
 Identities = 253/439 (57%), Positives = 297/439 (67%), Gaps = 53/439 (12%)

Query: 4   DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRE 62
           DI IEAMLEAPYKK+E++       ++       S S S +     S   E   RSRDR+
Sbjct: 7   DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66

Query: 63  RKKSKSRERKRSRSKERR-RSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLS 121
           R +   R   RSRS  R+ R RSRS DRR     RS                        
Sbjct: 67  RYR---RRNSRSRSPGRQCRHRSRSWDRRHGSESRS-----------------------R 100

Query: 122 RRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRD 181
             R   +  +R       EP+DNL+PEERDARTVFCMQLAARIRPRDLE+FFS VGKVRD
Sbjct: 101 DHRREDRVHYRSPPLATGEPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRD 160

Query: 182 VRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANN 241
           VR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAEKNR AAMANN
Sbjct: 161 VRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANN 220

Query: 242 LQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDS 301
           LQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSKGYGFITFSDS
Sbjct: 221 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 280

Query: 302 ECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTT-GRLQLM 360
           ECA++ALEQLNGFELAGRPM+VGHVTER D  +  +F D D+     +DLG+  GR QLM
Sbjct: 281 ECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDLGSAGGRFQLM 336

Query: 361 ARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQTEASALAAAAS 411
           A+LAEG G+Q+P  A           ALQ++G++  GA+             +AL A + 
Sbjct: 337 AKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL-----------NPAALTALSP 385

Query: 412 VQPLATQCFQLSNMFNPQT 430
              LA+QCFQLS++F PQT
Sbjct: 386 ALNLASQCFQLSSLFTPQT 404


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score =  102 bits (253), Expect = 1e-21
 Identities = 99/437 (22%), Positives = 184/437 (42%), Gaps = 85/437 (19%)

Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196
           P+ ++  + + A  + C      I        + + F+  G ++ + M  D  + + KG 
Sbjct: 70  PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129

Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256
           A+VE+    +  LA+      +LG   I     +   +A  + + L + +    R+YV S
Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189

Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316
           +H ++++D ++ +FE FG+I+S  L  D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249

Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358
            G+ ++VG         +T  T           A++A++ + + E       LGT G   
Sbjct: 250 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 309

Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSL---------------AFGAV------------ 390
           L++  L     L   P A  A Q  G +               + G V            
Sbjct: 310 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 369

Query: 391 ---------------ADLQTRLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 428
                          ++    LS+Q   S   ++A        ++   +    L NM +P
Sbjct: 370 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 429

Query: 429 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 480
           +       D +++ +V EEC K G V  + IY +K   + +      ++V+    +    
Sbjct: 430 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 484

Query: 481 AVNALHGRWFAGKMITA 497
           A+ AL+GRWFAG+ + A
Sbjct: 485 AIQALNGRWFAGRKVVA 501


>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score =  102 bits (253), Expect = 1e-21
 Identities = 99/437 (22%), Positives = 184/437 (42%), Gaps = 85/437 (19%)

Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196
           P+ ++  + + A  + C      I        + + F+  G ++ + M  D  + + KG 
Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172

Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256
           A+VE+    +  LA+      +LG   I     +   +A  + + L + +    R+YV S
Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232

Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316
           +H ++++D ++ +FE FG+I+S  L  D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292

Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358
            G+ ++VG         +T  T           A++A++ + + E       LGT G   
Sbjct: 293 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 352

Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSL---------------AFGAV------------ 390
           L++  L     L   P A  A Q  G +               + G V            
Sbjct: 353 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 412

Query: 391 ---------------ADLQTRLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 428
                          ++    LS+Q   S   ++A        ++   +    L NM +P
Sbjct: 413 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 472

Query: 429 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 480
           +       D +++ +V EEC K G V  + IY +K   + +      ++V+    +    
Sbjct: 473 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 527

Query: 481 AVNALHGRWFAGKMITA 497
           A+ AL+GRWFAG+ + A
Sbjct: 528 AIQALNGRWFAGRKVVA 544


>gi|7706607 LEM domain containing 3 [Homo sapiens]
          Length = 911

 Score =  102 bits (253), Expect = 1e-21
 Identities = 47/108 (43%), Positives = 68/108 (62%)

Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIA 476
           T C ++ NMF+P  E    W   I++ ++E+C+ + G++HI VDKNS +G VYVKC S  
Sbjct: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPE 842

Query: 477 AAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
            A  A  ALHG WF GK++T  Y+ L  YH+ FP ++T+   L PS +
Sbjct: 843 YAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNK 890


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score =  100 bits (249), Expect = 3e-21
 Identities = 95/405 (23%), Positives = 174/405 (42%), Gaps = 81/405 (20%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQAS 228
           + + F+  G ++ + M  D  + + KG A+VE+    +  LA+      +LG   I    
Sbjct: 128 IRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGR 187

Query: 229 QAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETG 288
            +   +A  + + L + +    R+YV S+H ++++D ++ +FE FG+I+S  L  D  TG
Sbjct: 188 PSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTG 247

Query: 289 RSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH--------VTERTD--------- 331
           + KGYGFI +  ++ ++ A+  +N F+L G+ ++VG         +T  T          
Sbjct: 248 KHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAV 307

Query: 332 -ASSASSFLDSDELERTGIDLGTTGRLQLMA-RLAEGTGLQIPPAAQQALQMSGSL---- 385
            A++A++ + + E       LGT G   L++  L     L   P A  A Q  G +    
Sbjct: 308 AAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVT 367

Query: 386 -----------AFGAV---------------------------ADLQTRLSQQTEASALA 407
                      + G V                           ++    LS+Q   S   
Sbjct: 368 PARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427

Query: 408 AAAS-------VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGV--IHIY 458
           ++A        ++   +    L NM +P+       D +++ +V EEC K G V  + IY
Sbjct: 428 SSARHMVMQKLLRKQESTVMVLRNMVDPK-----DIDDDLEGEVTEECGKFGAVNRVIIY 482

Query: 459 VDKNSAQGN------VYVKCPSIAAAIAAVNALHGRWFAGKMITA 497
            +K   + +      ++V+    +    A+ AL+GRWFAG+ + A
Sbjct: 483 QEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVA 527



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 40/98 (40%), Positives = 58/98 (59%)

Query: 227 ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSE 286
           A Q ++     MA   Q+  A   R+YVGS+++ + ED +R  F PFG I+SI +  DS 
Sbjct: 89  AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148

Query: 287 TGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVG 324
           T + KG+ F+ +   E A+ ALEQ+N   L GR +KVG
Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 14/65 (21%), Positives = 28/65 (43%)

Query: 142 IDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
           ID L  E R    ++   +   +   D++  F   GK++   +  D  + + KG  ++E+
Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257

Query: 202 VDVSS 206
               S
Sbjct: 258 EKAQS 262


>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
           [Homo sapiens]
          Length = 475

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 108/516 (20%), Positives = 194/516 (37%), Gaps = 94/516 (18%)

Query: 28  HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86
           +E + ++ K+++ R RSH R RS+ ++R+ RSRDR  +  +S  R R R   R +  +R 
Sbjct: 12  NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68

Query: 87  RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146
                 G  RSP    K    +R    +P          + K+     + P    +  +T
Sbjct: 69  AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126

Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188
           P+                 R AR ++   +   I    + +FF+   ++  +        
Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186

Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245
                 + K  A++EF  V     A+   G    G  + ++    +      M+ N    
Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245

Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
             G +         +L++G L   + +D ++ +   FG +++  L+ DS TG SKGY F 
Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305

Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356
            + D     +A+  LNG +L  + + V   +    A +A+       + +T +       
Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLVQRAS--VGAKNATLVSPPSTINQTPVT------ 357

Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLA 416
                       LQ+P      +QM G                                 
Sbjct: 358 ------------LQVPGLMSSQVQMGGH-------------------------------P 374

Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 470
           T+   L NM  P+   +     EI +DV +EC+K+G V  I + +          G ++V
Sbjct: 375 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV 434

Query: 471 KCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 506
           +  S+     A+  L GR FA +++   Y    +YH
Sbjct: 435 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 470


>gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform
           b [Homo sapiens]
          Length = 471

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 108/516 (20%), Positives = 196/516 (37%), Gaps = 98/516 (18%)

Query: 28  HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86
           +E + ++ K+++ R RSH R RS+ ++R+ RSRDR  +  +S  R R R   R +  +R 
Sbjct: 12  NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68

Query: 87  RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146
                 G  RSP    K    +R    +P          + K+     + P    +  +T
Sbjct: 69  AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126

Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188
           P+                 R AR ++   +   I    + +FF+   ++  +        
Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186

Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245
                 + K  A++EF  V     A+   G    G  + ++    +      M+ N    
Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245

Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
             G +         +L++G L   + +D ++ +   FG +++  L+ DS TG SKGY F 
Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305

Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356
            + D     +A+  LNG +L  + + V    +R    + ++ L +  + +T +       
Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLV----QRASVGAKNATLST--INQTPVT------ 353

Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLA 416
                       LQ+P      +QM G                                 
Sbjct: 354 ------------LQVPGLMSSQVQMGGH-------------------------------P 370

Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 470
           T+   L NM  P+   +     EI +DV +EC+K+G V  I + +          G ++V
Sbjct: 371 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV 430

Query: 471 KCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 506
           +  S+     A+  L GR FA +++   Y    +YH
Sbjct: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 466


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 53/178 (29%), Positives = 101/178 (56%), Gaps = 8/178 (4%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
           VF   L   I  + L E FS  GK+   +++SD   + SKG A+V F + S+   AI  +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157

Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
            G+ + G  + V   +  K+R A + +   + +     +Y+ +   ++ ++ L+ +F  +
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFT----NVYIKNFGGDMDDERLKDVFSKY 213

Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G+  S+++M DS +G+SKG+GF++F   E AKKA+E++NG ++ G+ + VG   ++ +
Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 12/163 (7%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227
           L++ FS  GK   V++++D +S +SKG  +V F    +   A+  + G+ + G  I V  
Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264

Query: 228 SQAEKNRAAAMANNLQ-------KGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQ 280
           +Q +  R A +    +       +G  G ++LY+ +L   I ++ LR  F  FG I  ++
Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323

Query: 281 LMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
           +M   E G+SKG+G I FS  E A KA+ ++NG  L  +P+ +
Sbjct: 324 VMQ--EEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 54/172 (31%), Positives = 84/172 (48%), Gaps = 18/172 (10%)

Query: 173 FSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQASQAE 231
           FSTVG V  +R+  D+ +RRS G AYV F+ ++    A+      ++ G  I +  SQ +
Sbjct: 30  FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRD 89

Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
                     L++   G   +++ +L  +I    L   F  FG+I S ++M D +   SK
Sbjct: 90  A--------YLRRSGIG--NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQ--GSK 137

Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD-----ASSASSF 338
           GY F+ F +   A +A+E++NG  L G  + VG    R D      S AS F
Sbjct: 138 GYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEF 189



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 27/72 (37%), Positives = 43/72 (59%)

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           LYVG LH ++TED+L   F   G + SI++  D  T RS GY ++ F     A+KAL+ +
Sbjct: 12  LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71

Query: 312 NGFELAGRPMKV 323
           N   + G+ +++
Sbjct: 72  NFDIIKGKSIRL 83


>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
           [Homo sapiens]
          Length = 285

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%)

Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
           N +  E DA  +F   L+     +DL+++F+  G+V D  +  D N+ RS+G  ++ F D
Sbjct: 61  NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120

Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
            +SV   +     R+ G  I       +  +A AM  +  K      +++VG L+   TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167

Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           + +R  F  FG IE+I+L MD +  + +G+ FITF + E  KK LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
           +N A     N  K      +++VG L ++ ++  L+  F  FG +    + MD  TGRS+
Sbjct: 52  QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111

Query: 292 GYGFITFSDSECAKKALEQ 310
           G+GFI F D+   +K L+Q
Sbjct: 112 GFGFILFKDAASVEKVLDQ 130


>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
           [Homo sapiens]
          Length = 332

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%)

Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
           N +  E DA  +F   L+     +DL+++F+  G+V D  +  D N+ RS+G  ++ F D
Sbjct: 61  NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120

Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
            +SV   +     R+ G  I       +  +A AM  +  K      +++VG L+   TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167

Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           + +R  F  FG IE+I+L MD +  + +G+ FITF + E  KK LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
           +N A     N  K      +++VG L ++ ++  L+  F  FG +    + MD  TGRS+
Sbjct: 52  QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111

Query: 292 GYGFITFSDSECAKKALEQ 310
           G+GFI F D+   +K L+Q
Sbjct: 112 GFGFILFKDAASVEKVLDQ 130


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%)

Query: 17  KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73
           K   +L+S+   E+R K++++  SR RSH R RS+ +  R RSR+R++ +S+SRERK  R
Sbjct: 38  KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97

Query: 74  SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
           SRS+ER++SRSRSR+R+ R R RS           R +    H  + SR R+RS+S  RK
Sbjct: 98  SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 145

Query: 134 DK 135
            +
Sbjct: 146 KR 147



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%)

Query: 12  EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71
           E  +K+ E K S    H     + ++ +SRSR  ++ RS+S+ERK+SR R R++ KSR R
Sbjct: 50  EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109

Query: 72  KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131
            R R K R RSRSRSR R  R R RS       +   + +I  P     S  R+ S  PF
Sbjct: 110 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167

Query: 132 R 132
           R
Sbjct: 168 R 168



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%)

Query: 16  KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68
           ++ +++  S    + RS+ R++ KSRSRS ERK       RS+S+ R R+R R R +S+S
Sbjct: 82  ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 141

Query: 69  RERKRSRSKERRRSRSRSRDRR---FRGR 94
           R+RK+   K RR SRS SR      FRGR
Sbjct: 142 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 7/118 (5%)

Query: 22  LSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRR 81
           L     HE + K  KK KS   + +++ S  K R+R    E  + + + ++R  S+ R  
Sbjct: 8   LKQGRRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66

Query: 82  SRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139
           SRSRSR+RR R R R      K  S  R +     S   SR R +S+S  R+ K  +R
Sbjct: 67  SRSRSRERRHRSRSR---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 118



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 21/74 (28%), Positives = 38/74 (51%)

Query: 16  KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
           +K   +  S +    R + R +S++RSRS +RK+   K R+ SR   R  S    R R+ 
Sbjct: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172

Query: 76  SKERRRSRSRSRDR 89
           + + + + +R  +R
Sbjct: 173 AMDAQEALARRLER 186



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%)

Query: 19  ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78
           E K    +    RS+ R +++SRSR+    RS+S++RK+  ++ R+ S+S  R  S    
Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167

Query: 79  RRRS 82
           R R+
Sbjct: 168 RGRN 171


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%)

Query: 17  KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73
           K   +L+S+   E+R K++++  SR RSH R RS+ +  R RSR+R++ +S+SRERK  R
Sbjct: 97  KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156

Query: 74  SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
           SRS+ER++SRSRSR+R+ R R RS           R +    H  + SR R+RS+S  RK
Sbjct: 157 SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 204

Query: 134 DK 135
            +
Sbjct: 205 KR 206



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%)

Query: 12  EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71
           E  +K+ E K S    H     + ++ +SRSR  ++ RS+S+ERK+SR R R++ KSR R
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168

Query: 72  KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131
            R R K R RSRSRSR R  R R RS       +   + +I  P     S  R+ S  PF
Sbjct: 169 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226

Query: 132 R 132
           R
Sbjct: 227 R 227



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%)

Query: 16  KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68
           ++ +++  S    + RS+ R++ KSRSRS ERK       RS+S+ R R+R R R +S+S
Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 200

Query: 69  RERKRSRSKERRRSRSRSRDRR---FRGR 94
           R+RK+   K RR SRS SR      FRGR
Sbjct: 201 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 229



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 53/164 (32%), Positives = 70/164 (42%), Gaps = 47/164 (28%)

Query: 17  KDENKLSSANGHEERSKKRKKSKSRSRSHERK------------RSKSKERKR--SRDRE 62
           +D+ K  S      R+ K   S+SRSRS ERK            RS+SKE +R  S+D+ 
Sbjct: 20  RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79

Query: 63  RKKSKSRE---------------------------RKRSRSKERRRSRSRSRDRRFRGRY 95
            KK KS E                           ++R  S+ R  SRSRSR+RR R R 
Sbjct: 80  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139

Query: 96  RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139
           R      K  S  R +     S   SR R +S+S  R+ K  +R
Sbjct: 140 R---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 177



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 21/74 (28%), Positives = 38/74 (51%)

Query: 16  KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
           +K   +  S +    R + R +S++RSRS +RK+   K R+ SR   R  S    R R+ 
Sbjct: 172 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231

Query: 76  SKERRRSRSRSRDR 89
           + + + + +R  +R
Sbjct: 232 AMDAQEALARRLER 245



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%)

Query: 19  ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78
           E K    +    RS+ R +++SRSR+    RS+S++RK+  ++ R+ S+S  R  S    
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226

Query: 79  RRRS 82
           R R+
Sbjct: 227 RGRN 230


>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
           sapiens]
          Length = 420

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 53/166 (31%), Positives = 88/166 (53%), Gaps = 12/166 (7%)

Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
           N +  ++D   +F   L+     +DL E+ S  G+V D  + +D  + RS+G  +V F D
Sbjct: 139 NASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKD 198

Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
            +SV   + L   ++ G  I       +  RA A+     KG   P +++VG L  + +E
Sbjct: 199 AASVDKVLELKEHKLDGKLI-------DPKRAKAL-----KGKEPPKKVFVGGLSPDTSE 246

Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
           + ++  F  FG IE+I+L MD++T   +G+ FIT++D E  KK LE
Sbjct: 247 EQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLE 292


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)

Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
           L  + ++   V+       +    L+E FS  GK   V+++ D N + SKG  +V +   
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241

Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
                A+  + G+ + G  I V  +Q +  R A +    ++           + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301

Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
              I ++ LR  F PFG I S ++M+  E GRSKG+GF+ FS  E A KA+ ++NG  + 
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359

Query: 318 GRPMKV 323
            +P+ V
Sbjct: 360 SKPLYV 365



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
           VF   L   I  + L + FS  G +   +++ D N   SKG A+V F    +   AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158

Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
            G  +    + V   ++ K R A +    ++ +     +Y+ +    + ++ L+ +F  F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214

Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G+  S+++M D   G+SKG+GF+++   E A KA+E++NG E++G+ + VG   ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
           L E FS  G V  +R+  D  +RRS G AYV F   +    A+      V+ G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I S +++ D E 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135

Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G SKGY F+ F   E A KA+E++NG  L  R + VG    R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)

Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
           S+ PM  LYVG LH ++TE ML   F P G + SI++  D  T RS GY ++ F     A
Sbjct: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65

Query: 305 KKALEQLNGFELAGRPMKV 323
           ++AL+ +N   + G+P+++
Sbjct: 66  ERALDTMNFDVIKGKPIRI 84


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)

Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
           L  + ++   V+       +    L+E FS  GK   V+++ D N + SKG  +V +   
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241

Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
                A+  + G+ + G  I V  +Q +  R A +    ++           + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301

Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
              I ++ LR  F PFG I S ++M+  E GRSKG+GF+ FS  E A KA+ ++NG  + 
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359

Query: 318 GRPMKV 323
            +P+ V
Sbjct: 360 SKPLYV 365



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
           VF   L   I  + L + FS  G +   +++ D N   SKG A+V F    +   AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158

Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
            G  +    + V   ++ K R A +    ++ +     +Y+ +    + ++ L+ +F  F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214

Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G+  S+++M D   G+SKG+GF+++   E A KA+E++NG E++G+ + VG   ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
           L E FS  G V  +R+  D  +RRS G AYV F   +    A+      V+ G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I S +++ D E 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135

Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G SKGY F+ F   E A KA+E++NG  L  R + VG    R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)

Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
           S+ PM  LYVG LH ++TE ML   F P G + SI++  D  T RS GY ++ F     A
Sbjct: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65

Query: 305 KKALEQLNGFELAGRPMKV 323
           ++AL+ +N   + G+P+++
Sbjct: 66  ERALDTMNFDVIKGKPIRI 84


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)

Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
           L  + ++   V+       +    L+E FS  GK   V+++ D N + SKG  +V +   
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241

Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
                A+  + G+ + G  I V  +Q +  R A +    ++           + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301

Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
              I ++ LR  F PFG I S ++M+  E GRSKG+GF+ FS  E A KA+ ++NG  + 
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359

Query: 318 GRPMKV 323
            +P+ V
Sbjct: 360 SKPLYV 365



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
           VF   L   I  + L + FS  G +   +++ D N   SKG A+V F    +   AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158

Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
            G  +    + V   ++ K R A +    ++ +     +Y+ +    + ++ L+ +F  F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214

Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G+  S+++M D   G+SKG+GF+++   E A KA+E++NG E++G+ + VG   ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
           L E FS  G V  +R+  D  +RRS G AYV F   +    A+      V+ G PI +  
Sbjct: 27  LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86

Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
           SQ +         +L+K   G   +++ +L  +I    L   F  FG I S +++ D E 
Sbjct: 87  SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135

Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
           G SKGY F+ F   E A KA+E++NG  L  R + VG    R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)

Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
           S+ PM  LYVG LH ++TE ML   F P G + SI++  D  T RS GY ++ F     A
Sbjct: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65

Query: 305 KKALEQLNGFELAGRPMKV 323
           ++AL+ +N   + G+P+++
Sbjct: 66  ERALDTMNFDVIKGKPIRI 84


>gi|20373175 musashi 2 isoform a [Homo sapiens]
          Length = 328

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 8/161 (4%)

Query: 149 ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVP 208
           + D   +F   L+ +  P  L ++FS  G++R+  ++ D  ++RS+G  +V F D +SV 
Sbjct: 17  QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75

Query: 209 LAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRG 268
                   +VLG P     S+    + A       K      +++VG L  N   + ++ 
Sbjct: 76  -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128

Query: 269 IFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
            FE FG++E   LM D  T R +G+GF+TF + +  +K  E
Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 231 EKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRS 290
           E N +   + +       P ++++G L +  + D LR  F  FG I    +M D  T RS
Sbjct: 2   EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61

Query: 291 KGYGFITFSDSECAKKALEQ 310
           +G+GF+TF+D     K L Q
Sbjct: 62  RGFGFVTFADPASVDKVLGQ 81


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 50/194 (25%), Positives = 101/194 (52%), Gaps = 8/194 (4%)

Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
           E+   +T++   L+  +    + + FS +G  ++ +MI D  +  +    +VEF +    
Sbjct: 2   EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59

Query: 208 PLAIG-LTGQRVLGVPIIVQ----ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262
             A+  + G++++G  + V      S  +K+ +++   + Q+ S     ++VG L   IT
Sbjct: 60  AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR-SQDHFHVFVGDLSPEIT 118

Query: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
            + ++  F PFGRI   +++ D  TG+SKGYGF++F +   A+ A++Q+ G  L GR ++
Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178

Query: 323 VGHVTERTDASSAS 336
               T +  A  ++
Sbjct: 179 TNWATRKPPAPKST 192



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 17/188 (9%)

Query: 146 TPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVS 205
           T   +D   VF   L+  I   D++  F+  G++ D R++ D  + +SKG  +V F +  
Sbjct: 99  TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158

Query: 206 SVPLAIGLTGQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYV 254
               AI   G + LG            P   +++     +  +    + + S     +Y 
Sbjct: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218

Query: 255 GSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314
           G +   +TE ++R  F PFG+I  I++  D      KGY F+ F+  E A  A+  +NG 
Sbjct: 219 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGT 272

Query: 315 ELAGRPMK 322
            + G  +K
Sbjct: 273 TIEGHVVK 280


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 48/190 (25%), Positives = 97/190 (51%), Gaps = 11/190 (5%)

Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
           E+   +T++   L+  +    + + FS +G  ++ +MI D  +  +    +VEF +    
Sbjct: 2   EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59

Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
             A+  + G++++G  +        K   A   ++ +K ++    ++VG L   IT + +
Sbjct: 60  AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111

Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
           +  F PFGRI   +++ D  TG+SKGYGF++F +   A+ A++Q+ G  L GR ++    
Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171

Query: 327 TERTDASSAS 336
           T +  A  ++
Sbjct: 172 TRKPPAPKST 181



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 17/179 (9%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
           VF   L+  I   D++  F+  G++ D R++ D  + +SKG  +V F +      AI   
Sbjct: 97  VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156

Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
           G + LG            P   +++     +  +    + + S     +Y G +   +TE
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216

Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
            ++R  F PFG+I  I++  D      KGY F+ F+  E A  A+  +NG  + G  +K
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 56/184 (30%), Positives = 90/184 (48%), Gaps = 13/184 (7%)

Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
           E     TV+   L  ++    L E F   G V +  M  DR + + +G  +VEF+     
Sbjct: 8   ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67

Query: 208 PLAIGLTGQ-RVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
             AI +    ++ G PI V       N+A+A   NL  G+     +++G+L   I E +L
Sbjct: 68  DYAIKIMNMIKLYGKPIRV-------NKASAHNKNLDVGA----NIFIGNLDPEIDEKLL 116

Query: 267 RGIFEPFGRI-ESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH 325
              F  FG I ++ ++M D +TG SKGY FI F+  + +  A+E +NG  L  RP+ V +
Sbjct: 117 YDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSY 176

Query: 326 VTER 329
             ++
Sbjct: 177 AFKK 180


>gi|25121993 musashi 2 isoform b [Homo sapiens]
          Length = 251

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 8/155 (5%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
           +F   L+ +  P  L ++FS  G++R+  ++ D  ++RS+G  +V F D +SV       
Sbjct: 19  MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71

Query: 215 GQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFG 274
             +VLG P     S+    + A       K      +++VG L  N   + ++  FE FG
Sbjct: 72  -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130

Query: 275 RIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
           ++E   LM D  T R +G+GF+TF + +  +K  E
Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 23/60 (38%), Positives = 34/60 (56%)

Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           ++++G L +  + D LR  F  FG I    +M D  T RS+G+GF+TF+D     K L Q
Sbjct: 18  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 14/49 (28%), Positives = 27/49 (55%)

Query: 153 RTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
           + +F   L+A     D++++F   GKV D  ++ D+ + R +G  +V F
Sbjct: 106 KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 154


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 65/195 (33%), Positives = 90/195 (46%), Gaps = 33/195 (16%)

Query: 12  EAPYKKDENKLSSANGHEERS-KKRKKSKSRSRSHE-RKRSKSKERKRSRDRERKKSKSR 69
           E  Y + E++ +S +G    S K  + + +RSRS E  +RS+SK R RS  R R +  SR
Sbjct: 6   EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65

Query: 70  ERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKS 129
            R  +RS+ R RS  RSR R +   YR                         RR S S S
Sbjct: 66  -RHYTRSRSRSRSHRRSRSRSYSRDYR-------------------------RRHSHSHS 99

Query: 130 PFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRN 189
           P    +   R   +   P+      VF + L      RDL E FS  G + DV ++ D+ 
Sbjct: 100 PMSTRR---RHVGNRANPDPNCCLGVFGLSLYT--TERDLREVFSKYGPIADVSIVYDQQ 154

Query: 190 SRRSKGIAYVEFVDV 204
           SRRS+G A+V F +V
Sbjct: 155 SRRSRGFAFVYFENV 169



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 27/72 (37%), Positives = 43/72 (59%)

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           L V  L    TE  LR +F  +G I  + ++ D ++ RS+G+ F+ F + + AK+A E+ 
Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179

Query: 312 NGFELAGRPMKV 323
           NG EL GR ++V
Sbjct: 180 NGMELDGRRIRV 191


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 48/198 (24%), Positives = 99/198 (50%), Gaps = 11/198 (5%)

Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
           ++   RT++   L+  +    + + FS +G  +  +MI++  S  +    +VEF +    
Sbjct: 4   DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61

Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
             A+  + G+++LG  +        K   A   ++ +K ++    ++VG L   IT + +
Sbjct: 62  AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113

Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
           +  F PFG+I   +++ D  TG+SKGYGF++F +   A+ A+  + G  L GR ++    
Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173

Query: 327 TERTDASSASSFLDSDEL 344
           T +  A  ++   ++ +L
Sbjct: 174 TRKPPAPKSTQENNTKQL 191



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 58/231 (25%), Positives = 98/231 (42%), Gaps = 23/231 (9%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
           VF   L+  I   D++  F+  GK+ D R++ D  + +SKG  +V F +      AI   
Sbjct: 99  VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158

Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
           G + LG            P   +++Q    +     + + + S     +Y G +   +T+
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218

Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
            ++R  F PFG+I  I++  +      KGY F+ FS  E A  A+  +NG  + G  +K 
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC 272

Query: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRL-QLMARLAEGTGLQIPP 373
               E  D +     +D  +  +     G   +  Q MA      G Q+PP
Sbjct: 273 YWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMA-----NGWQVPP 318


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 45/171 (26%), Positives = 85/171 (49%), Gaps = 8/171 (4%)

Query: 141 PIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVE 200
           P++    E+   R +F   L+       L  ++   GK+ D  ++ D  S+RS+G  +V 
Sbjct: 9   PLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVT 68

Query: 201 FVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMR-LYVGSLHF 259
           F  ++ V  A+          P  +     E  RA A   + + G+   ++ L+VG +  
Sbjct: 69  FSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKE 121

Query: 260 NITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
           +  E  LR  FE +G+I++I+++ D ++G+ +G+GF+TF D +   K + Q
Sbjct: 122 DTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQ 172


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 56/185 (30%), Positives = 95/185 (51%), Gaps = 13/185 (7%)

Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227
           L++ F   G    V++++D  S +SKG  +V F        A+  + G+ + G  I V  
Sbjct: 207 LKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGR 265

Query: 228 SQAEKNRAAAMANNLQKGSAGPM------RLYVGSLHFNITEDMLRGIFEPFGRIESIQL 281
           +Q +  R   +    ++     +       LYV +L   I ++ LR  F PFG I S ++
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKV 325

Query: 282 MMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDS 341
           MM  E GRSKG+GF+ FS  E A KA+ ++NG  +A +P+ V  + +R +   A  +L +
Sbjct: 326 MM--EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA-LAQRKEERQA--YLTN 380

Query: 342 DELER 346
           + ++R
Sbjct: 381 EYMQR 385



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 52/194 (26%), Positives = 97/194 (50%), Gaps = 16/194 (8%)

Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
           +F   L   I  + L +  S  G +    ++ D N   SKG  +V F    +   AI  +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158

Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
            G  + G  + V   ++ K R A +    ++       +Y+ +   ++ ++ L+ +F  F
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFP----NVYIKNFGEDMDDERLKDLFGKF 214

Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDAS 333
           G   S+++M D E+G+SKG+GF++F   E A+KA++++NG EL G+ + VG   ++ +  
Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273

Query: 334 SASSFLDSDELERT 347
           +        EL+RT
Sbjct: 274 T--------ELKRT 279



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 27/72 (37%), Positives = 43/72 (59%)

Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
           LYVG LH ++TE ML   F P G I SI++  D  T  S  Y ++ F  ++ A+ AL+ +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72

Query: 312 NGFELAGRPMKV 323
           N   + G+P+++
Sbjct: 73  NFDVIKGKPVRI 84


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 7/142 (4%)

Query: 16  KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
           +++E +   A   E R + R +S+  SR+ +R+ S+S++ KRSR RER++S+SR+R+RSR
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334

Query: 76  SKER--RRSRSRSRD-RRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFR 132
           S +R  R+ RSRSRD RR + R R  Y   K  S  R +     S +  +R S  K    
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSY---KHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391

Query: 133 KDKSPVREPID-NLTPEERDAR 153
           K  S  ++  D N   +E D +
Sbjct: 392 KSGSREKQSEDTNTESKESDTK 413



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 48/137 (35%), Positives = 74/137 (54%), Gaps = 14/137 (10%)

Query: 12  EAPYKKDENKLSSANGHEERSKKR---KKSKSRSRSHERKRSKSKERKRSRDRERKKSKS 68
           E   +++E +       EER K+R   ++ + RSRS  R  S++ +R+ SR R+ K+S+S
Sbjct: 260 EREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS 319

Query: 69  RERKRSRSKERRRSRSRSR-DRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRS 127
           RER+RSRS++RRRSRS  R +R+ R R R      +  S  R +    H     R +SR 
Sbjct: 320 RERRRSRSRDRRRSRSHDRSERKHRSRSRD-----RRRSKSRDRKSYKH-----RSKSRD 369

Query: 128 KSPFRKDKSPVREPIDN 144
           +   RK K   +   D+
Sbjct: 370 REQDRKSKEKEKRGSDD 386



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 2/109 (1%)

Query: 25  ANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRS 84
           A   E + K RK+++   R    K+ K +  +R ++RER++ +   ++R   +ER + R+
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284

Query: 85  RSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
           R R+RR R R RS +S     S  R      H    SR R RS+S  R+
Sbjct: 285 RDRERRKRSRSRSRHSSR--TSDRRCSRSRDHKRSRSRERRRSRSRDRR 331



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 15/161 (9%)

Query: 7   IEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKS 66
           I+A +E   +K   +    +  E   K++++ + R +  ER+R + + ++R  + ER+K 
Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282

Query: 67  KSRE---RKRSRSKERRRSR------SRSRD-RRFRGR-YRSPYSGPKFNSAIRGKIGLP 115
           ++R+   RKRSRS+ R  SR      SRSRD +R R R  R   S  +  S    +    
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342

Query: 116 HSIKLSRRRSRSKSPFRKD---KSPVREPIDNLTPEERDAR 153
           H  + SR R RSKS  RK    +S  R+   +   +E++ R
Sbjct: 343 HRSR-SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,617,437
Number of Sequences: 37866
Number of extensions: 755854
Number of successful extensions: 22020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 679
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 6519
Number of HSP's gapped (non-prelim): 6449
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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