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Search of human proteins with 4757926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757926 RNA binding motif protein 39 isoform b [Homo
sapiens]
(524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 1025 0.0
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 1018 0.0
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 474 e-134
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 461 e-130
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 437 e-122
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 102 1e-21
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 102 1e-21
gi|7706607 LEM domain containing 3 [Homo sapiens] 102 1e-21
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 100 3e-21
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 92 2e-18
gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo... 91 3e-18
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 87 3e-17
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 83 5e-16
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 83 5e-16
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 83 5e-16
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 83 5e-16
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 83 7e-16
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 81 3e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 81 3e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 81 3e-15
gi|20373175 musashi 2 isoform a [Homo sapiens] 80 3e-15
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 80 6e-15
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 79 8e-15
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 79 8e-15
gi|25121993 musashi 2 isoform b [Homo sapiens] 79 1e-14
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 79 1e-14
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 78 2e-14
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 77 5e-14
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 76 7e-14
gi|52426743 cisplatin resistance-associated overexpressed protei... 76 9e-14
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 1025 bits (2649), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD
Sbjct: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
Query: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL
Sbjct: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR
Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN
Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD
Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM
Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF 420
ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF
Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCF 420
Query: 421 QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA 480
QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA
Sbjct: 421 QLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIA 480
Query: 481 AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR
Sbjct: 481 AVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 1018 bits (2632), Expect = 0.0
Identities = 524/530 (98%), Positives = 524/530 (98%), Gaps = 6/530 (1%)
Query: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD
Sbjct: 1 MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRD 60
Query: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL
Sbjct: 61 RERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKL 120
Query: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR
Sbjct: 121 SRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVR 180
Query: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN
Sbjct: 181 DVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMAN 240
Query: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD
Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300
Query: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM
Sbjct: 301 SECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLM 360
Query: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA------DLQTRLSQQTEASALAAAASVQP 414
ARLAEGTGLQIPPAAQQALQMSGSLAFGAVA DLQTRLSQQTEASALAAAASVQP
Sbjct: 361 ARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQP 420
Query: 415 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 474
LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS
Sbjct: 421 LATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPS 480
Query: 475 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR
Sbjct: 481 IAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530
>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
Length = 439
Score = 474 bits (1220), Expect = e-134
Identities = 274/465 (58%), Positives = 327/465 (70%), Gaps = 71/465 (15%)
Query: 4 DIDIEAMLEAPYKKDENKL---------------SSANGHEERS--------KKRKKSKS 40
DI IEAMLEAPYKK+E++ S++N E S K+K+S+S
Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSKKKRSRS 66
Query: 41 RSRSHERKRSKSKERKRSRDRE-RKKSKSRE-RKRSRSKERRR-SRSRSRDRRFRGR--Y 95
++S +RKRS+S++R R R R R +S R+ R RSRS +RR S SRSRD R R Y
Sbjct: 67 HNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHY 126
Query: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTV 155
RSP + R SKSP ++KSPVREP+DNL+PEERDARTV
Sbjct: 127 RSP------------------PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTV 168
Query: 156 FCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTG 215
FCMQLAARIRPRDLE+FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTG
Sbjct: 169 FCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTG 228
Query: 216 QRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGR 275
QR+LGVPIIVQASQAEKNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+
Sbjct: 229 QRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGK 288
Query: 276 IESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSA 335
I++I LM DS+TGRSKGYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D +
Sbjct: 289 IDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD 348
Query: 336 SSFLDSDELERTGIDLGTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSL 385
+F D D+ +DLG+ GR QLMA+LAEG G+Q+P A ALQ++G++
Sbjct: 349 ITFPDGDQ----ELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAV 404
Query: 386 AFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 430
GA+ +AL A + LA+QCFQLS++F PQT
Sbjct: 405 PLGAL-----------NPAALTALSPALNLASQCFQLSSLFTPQT 438
>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
Length = 423
Score = 461 bits (1186), Expect = e-130
Identities = 266/449 (59%), Positives = 314/449 (69%), Gaps = 55/449 (12%)
Query: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60
DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD
Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66
Query: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111
R R++ S+SR R RSRS +RR S SRSRD R R YRSP
Sbjct: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113
Query: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171
+ R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+
Sbjct: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168
Query: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231
FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE
Sbjct: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228
Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK
Sbjct: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288
Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351
GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL
Sbjct: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344
Query: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQT 401
G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+
Sbjct: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393
Query: 402 EASALAAAASVQPLATQCFQLSNMFNPQT 430
+AL A + LA+QCFQLS++F PQT
Sbjct: 394 NPAALTALSPALNLASQCFQLSSLFTPQT 422
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 437 bits (1123), Expect = e-122
Identities = 253/439 (57%), Positives = 297/439 (67%), Gaps = 53/439 (12%)
Query: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRE 62
DI IEAMLEAPYKK+E++ ++ S S S + S E RSRDR+
Sbjct: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66
Query: 63 RKKSKSRERKRSRSKERR-RSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLS 121
R + R RSRS R+ R RSRS DRR RS
Sbjct: 67 RYR---RRNSRSRSPGRQCRHRSRSWDRRHGSESRS-----------------------R 100
Query: 122 RRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRD 181
R + +R EP+DNL+PEERDARTVFCMQLAARIRPRDLE+FFS VGKVRD
Sbjct: 101 DHRREDRVHYRSPPLATGEPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRD 160
Query: 182 VRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANN 241
VR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAEKNR AAMANN
Sbjct: 161 VRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANN 220
Query: 242 LQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDS 301
LQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSKGYGFITFSDS
Sbjct: 221 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 280
Query: 302 ECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTT-GRLQLM 360
ECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DLG+ GR QLM
Sbjct: 281 ECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDLGSAGGRFQLM 336
Query: 361 ARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQTEASALAAAAS 411
A+LAEG G+Q+P A ALQ++G++ GA+ +AL A +
Sbjct: 337 AKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL-----------NPAALTALSP 385
Query: 412 VQPLATQCFQLSNMFNPQT 430
LA+QCFQLS++F PQT
Sbjct: 386 ALNLASQCFQLSSLFTPQT 404
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 102 bits (253), Expect = 1e-21
Identities = 99/437 (22%), Positives = 184/437 (42%), Gaps = 85/437 (19%)
Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196
P+ ++ + + A + C I + + F+ G ++ + M D + + KG
Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129
Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256
A+VE+ + LA+ +LG I + +A + + L + + R+YV S
Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189
Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316
+H ++++D ++ +FE FG+I+S L D TG+ KGYGFI + ++ ++ A+ +N F+L
Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249
Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358
G+ ++VG +T T A++A++ + + E LGT G
Sbjct: 250 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 309
Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSL---------------AFGAV------------ 390
L++ L L P A A Q G + + G V
Sbjct: 310 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 369
Query: 391 ---------------ADLQTRLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 428
++ LS+Q S ++A ++ + L NM +P
Sbjct: 370 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 429
Query: 429 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 480
+ D +++ +V EEC K G V + IY +K + + ++V+ +
Sbjct: 430 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 484
Query: 481 AVNALHGRWFAGKMITA 497
A+ AL+GRWFAG+ + A
Sbjct: 485 AIQALNGRWFAGRKVVA 501
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 102 bits (253), Expect = 1e-21
Identities = 99/437 (22%), Positives = 184/437 (42%), Gaps = 85/437 (19%)
Query: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196
P+ ++ + + A + C I + + F+ G ++ + M D + + KG
Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
Query: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256
A+VE+ + LA+ +LG I + +A + + L + + R+YV S
Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
Query: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316
+H ++++D ++ +FE FG+I+S L D TG+ KGYGFI + ++ ++ A+ +N F+L
Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
Query: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358
G+ ++VG +T T A++A++ + + E LGT G
Sbjct: 293 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 352
Query: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSL---------------AFGAV------------ 390
L++ L L P A A Q G + + G V
Sbjct: 353 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 412
Query: 391 ---------------ADLQTRLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 428
++ LS+Q S ++A ++ + L NM +P
Sbjct: 413 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 472
Query: 429 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 480
+ D +++ +V EEC K G V + IY +K + + ++V+ +
Sbjct: 473 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 527
Query: 481 AVNALHGRWFAGKMITA 497
A+ AL+GRWFAG+ + A
Sbjct: 528 AIQALNGRWFAGRKVVA 544
>gi|7706607 LEM domain containing 3 [Homo sapiens]
Length = 911
Score = 102 bits (253), Expect = 1e-21
Identities = 47/108 (43%), Positives = 68/108 (62%)
Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIA 476
T C ++ NMF+P E W I++ ++E+C+ + G++HI VDKNS +G VYVKC S
Sbjct: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPE 842
Query: 477 AAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
A A ALHG WF GK++T Y+ L YH+ FP ++T+ L PS +
Sbjct: 843 YAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNK 890
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 100 bits (249), Expect = 3e-21
Identities = 95/405 (23%), Positives = 174/405 (42%), Gaps = 81/405 (20%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQAS 228
+ + F+ G ++ + M D + + KG A+VE+ + LA+ +LG I
Sbjct: 128 IRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGR 187
Query: 229 QAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETG 288
+ +A + + L + + R+YV S+H ++++D ++ +FE FG+I+S L D TG
Sbjct: 188 PSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTG 247
Query: 289 RSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH--------VTERTD--------- 331
+ KGYGFI + ++ ++ A+ +N F+L G+ ++VG +T T
Sbjct: 248 KHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAV 307
Query: 332 -ASSASSFLDSDELERTGIDLGTTGRLQLMA-RLAEGTGLQIPPAAQQALQMSGSL---- 385
A++A++ + + E LGT G L++ L L P A A Q G +
Sbjct: 308 AAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVT 367
Query: 386 -----------AFGAV---------------------------ADLQTRLSQQTEASALA 407
+ G V ++ LS+Q S
Sbjct: 368 PARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427
Query: 408 AAAS-------VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGV--IHIY 458
++A ++ + L NM +P+ D +++ +V EEC K G V + IY
Sbjct: 428 SSARHMVMQKLLRKQESTVMVLRNMVDPK-----DIDDDLEGEVTEECGKFGAVNRVIIY 482
Query: 459 VDKNSAQGN------VYVKCPSIAAAIAAVNALHGRWFAGKMITA 497
+K + + ++V+ + A+ AL+GRWFAG+ + A
Sbjct: 483 QEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVA 527
Score = 75.5 bits (184), Expect = 1e-13
Identities = 40/98 (40%), Positives = 58/98 (59%)
Query: 227 ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSE 286
A Q ++ MA Q+ A R+YVGS+++ + ED +R F PFG I+SI + DS
Sbjct: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
Query: 287 TGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVG 324
T + KG+ F+ + E A+ ALEQ+N L GR +KVG
Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
Score = 32.0 bits (71), Expect = 1.4
Identities = 14/65 (21%), Positives = 28/65 (43%)
Query: 142 IDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
ID L E R ++ + + D++ F GK++ + D + + KG ++E+
Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
Query: 202 VDVSS 206
S
Sbjct: 258 EKAQS 262
>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
[Homo sapiens]
Length = 475
Score = 91.7 bits (226), Expect = 2e-18
Identities = 108/516 (20%), Positives = 194/516 (37%), Gaps = 94/516 (18%)
Query: 28 HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86
+E + ++ K+++ R RSH R RS+ ++R+ RSRDR + +S R R R R + +R
Sbjct: 12 NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68
Query: 87 RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146
G RSP K +R +P + K+ + P + +T
Sbjct: 69 AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126
Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188
P+ R AR ++ + I + +FF+ ++ +
Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186
Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245
+ K A++EF V A+ G G + ++ + M+ N
Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245
Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
G + +L++G L + +D ++ + FG +++ L+ DS TG SKGY F
Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356
+ D +A+ LNG +L + + V + A +A+ + +T +
Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLVQRAS--VGAKNATLVSPPSTINQTPVT------ 357
Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLA 416
LQ+P +QM G
Sbjct: 358 ------------LQVPGLMSSQVQMGGH-------------------------------P 374
Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 470
T+ L NM P+ + EI +DV +EC+K+G V I + + G ++V
Sbjct: 375 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV 434
Query: 471 KCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 506
+ S+ A+ L GR FA +++ Y +YH
Sbjct: 435 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 470
>gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform
b [Homo sapiens]
Length = 471
Score = 90.5 bits (223), Expect = 3e-18
Identities = 108/516 (20%), Positives = 196/516 (37%), Gaps = 98/516 (18%)
Query: 28 HEERSKKRKKSKSRSRSHERKRSKSKERK-RSRDRERKKSKSRERKRSRSKERRRSRSRS 86
+E + ++ K+++ R RSH R RS+ ++R+ RSRDR + +S R R R R + +R
Sbjct: 12 NENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR---RSKPLTRG 68
Query: 87 RDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLT 146
G RSP K +R +P + K+ + P + +T
Sbjct: 69 AKEEHGGLIRSPRHEKK--KKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMT 126
Query: 147 PE----------------ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDR-- 188
P+ R AR ++ + I + +FF+ ++ +
Sbjct: 127 PDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPV 186
Query: 189 ---NSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKG 245
+ K A++EF V A+ G G + ++ + M+ N
Sbjct: 187 LAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSENPSVY 245
Query: 246 SAGPM---------RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFI 296
G + +L++G L + +D ++ + FG +++ L+ DS TG SKGY F
Sbjct: 246 VPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFC 305
Query: 297 TFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGR 356
+ D +A+ LNG +L + + V +R + ++ L + + +T +
Sbjct: 306 EYVDINVTDQAIAGLNGMQLGDKKLLV----QRASVGAKNATLST--INQTPVT------ 353
Query: 357 LQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLA 416
LQ+P +QM G
Sbjct: 354 ------------LQVPGLMSSQVQMGGH-------------------------------P 370
Query: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKN------SAQGNVYV 470
T+ L NM P+ + EI +DV +EC+K+G V I + + G ++V
Sbjct: 371 TEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFV 430
Query: 471 KCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYH 506
+ S+ A+ L GR FA +++ Y +YH
Sbjct: 431 EFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH 466
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 87.4 bits (215), Expect = 3e-17
Identities = 53/178 (29%), Positives = 101/178 (56%), Gaps = 8/178 (4%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
VF L I + L E FS GK+ +++SD + SKG A+V F + S+ AI +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
G+ + G + V + K+R A + + + + +Y+ + ++ ++ L+ +F +
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFT----NVYIKNFGGDMDDERLKDVFSKY 213
Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G+ S+++M DS +G+SKG+GF++F E AKKA+E++NG ++ G+ + VG ++ +
Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270
Score = 75.9 bits (185), Expect = 9e-14
Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 12/163 (7%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227
L++ FS GK V++++D +S +SKG +V F + A+ + G+ + G I V
Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264
Query: 228 SQAEKNRAAAMANNLQ-------KGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQ 280
+Q + R A + + +G G ++LY+ +L I ++ LR F FG I ++
Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323
Query: 281 LMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
+M E G+SKG+G I FS E A KA+ ++NG L +P+ +
Sbjct: 324 VMQ--EEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
Score = 68.6 bits (166), Expect = 1e-11
Identities = 54/172 (31%), Positives = 84/172 (48%), Gaps = 18/172 (10%)
Query: 173 FSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQASQAE 231
FSTVG V +R+ D+ +RRS G AYV F+ ++ A+ ++ G I + SQ +
Sbjct: 30 FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRD 89
Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
L++ G +++ +L +I L F FG+I S ++M D + SK
Sbjct: 90 A--------YLRRSGIG--NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQ--GSK 137
Query: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD-----ASSASSF 338
GY F+ F + A +A+E++NG L G + VG R D S AS F
Sbjct: 138 GYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEF 189
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/72 (37%), Positives = 43/72 (59%)
Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
LYVG LH ++TED+L F G + SI++ D T RS GY ++ F A+KAL+ +
Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
Query: 312 NGFELAGRPMKV 323
N + G+ +++
Sbjct: 72 NFDIIKGKSIRL 83
>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
[Homo sapiens]
Length = 285
Score = 83.2 bits (204), Expect = 5e-16
Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%)
Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
N + E DA +F L+ +DL+++F+ G+V D + D N+ RS+G ++ F D
Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120
Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
+SV + R+ G I + +A AM + K +++VG L+ TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167
Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
+ +R F FG IE+I+L MD + + +G+ FITF + E KK LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214
Score = 53.9 bits (128), Expect = 3e-07
Identities = 26/79 (32%), Positives = 42/79 (53%)
Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
+N A N K +++VG L ++ ++ L+ F FG + + MD TGRS+
Sbjct: 52 QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111
Query: 292 GYGFITFSDSECAKKALEQ 310
G+GFI F D+ +K L+Q
Sbjct: 112 GFGFILFKDAASVEKVLDQ 130
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 83.2 bits (204), Expect = 5e-16
Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 13/167 (7%)
Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
N + E DA +F L+ +DL+++F+ G+V D + D N+ RS+G ++ F D
Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120
Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
+SV + R+ G I + +A AM + K +++VG L+ TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167
Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
+ +R F FG IE+I+L MD + + +G+ FITF + E KK LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214
Score = 53.9 bits (128), Expect = 3e-07
Identities = 26/79 (32%), Positives = 42/79 (53%)
Query: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
+N A N K +++VG L ++ ++ L+ F FG + + MD TGRS+
Sbjct: 52 QNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSR 111
Query: 292 GYGFITFSDSECAKKALEQ 310
G+GFI F D+ +K L+Q
Sbjct: 112 GFGFILFKDAASVEKVLDQ 130
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 83.2 bits (204), Expect = 5e-16
Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%)
Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73
K +L+S+ E+R K++++ SR RSH R RS+ + R RSR+R++ +S+SRERK R
Sbjct: 38 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97
Query: 74 SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
SRS+ER++SRSRSR+R+ R R RS R + H + SR R+RS+S RK
Sbjct: 98 SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 145
Query: 134 DK 135
+
Sbjct: 146 KR 147
Score = 77.0 bits (188), Expect = 4e-14
Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 12 EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71
E +K+ E K S H + ++ +SRSR ++ RS+S+ERK+SR R R++ KSR R
Sbjct: 50 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 109
Query: 72 KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131
R R K R RSRSRSR R R R RS + + +I P S R+ S PF
Sbjct: 110 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
Query: 132 R 132
R
Sbjct: 168 R 168
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%)
Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68
++ +++ S + RS+ R++ KSRSRS ERK RS+S+ R R+R R R +S+S
Sbjct: 82 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 141
Query: 69 RERKRSRSKERRRSRSRSRDRR---FRGR 94
R+RK+ K RR SRS SR FRGR
Sbjct: 142 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 170
Score = 55.5 bits (132), Expect = 1e-07
Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 22 LSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRR 81
L HE + K KK KS + +++ S K R+R E + + + ++R S+ R
Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 66
Query: 82 SRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139
SRSRSR+RR R R R K S R + S SR R +S+S R+ K +R
Sbjct: 67 SRSRSRERRHRSRSR---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 118
Score = 36.6 bits (83), Expect = 0.058
Identities = 21/74 (28%), Positives = 38/74 (51%)
Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
+K + S + R + R +S++RSRS +RK+ K R+ SR R S R R+
Sbjct: 113 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172
Query: 76 SKERRRSRSRSRDR 89
+ + + + +R +R
Sbjct: 173 AMDAQEALARRLER 186
Score = 33.5 bits (75), Expect = 0.49
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Query: 19 ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78
E K + RS+ R +++SRSR+ RS+S++RK+ ++ R+ S+S R S
Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 167
Query: 79 RRRS 82
R R+
Sbjct: 168 RGRN 171
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 83.2 bits (204), Expect = 5e-16
Identities = 52/122 (42%), Positives = 77/122 (63%), Gaps = 15/122 (12%)
Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKE-RKRSRDRERKKSKSRERK--R 73
K +L+S+ E+R K++++ SR RSH R RS+ + R RSR+R++ +S+SRERK R
Sbjct: 97 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156
Query: 74 SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
SRS+ER++SRSRSR+R+ R R RS R + H + SR R+RS+S RK
Sbjct: 157 SRSRERKKSRSRSRERKRRIRSRS-----------RSRSRHRHRTR-SRSRTRSRSRDRK 204
Query: 134 DK 135
+
Sbjct: 205 KR 206
Score = 77.0 bits (188), Expect = 4e-14
Identities = 48/121 (39%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 12 EAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRER 71
E +K+ E K S H + ++ +SRSR ++ RS+S+ERK+SR R R++ KSR R
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Query: 72 KRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPF 131
R R K R RSRSRSR R R R RS + + +I P S R+ S PF
Sbjct: 169 SRER-KRRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226
Query: 132 R 132
R
Sbjct: 227 R 227
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 10/89 (11%)
Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERK-------RSKSKERKRSRDRERKKSKS 68
++ +++ S + RS+ R++ KSRSRS ERK RS+S+ R R+R R R +S+S
Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS 200
Query: 69 RERKRSRSKERRRSRSRSRDRR---FRGR 94
R+RK+ K RR SRS SR FRGR
Sbjct: 201 RDRKKRIEKPRRFSRSLSRTPSPPPFRGR 229
Score = 53.5 bits (127), Expect = 5e-07
Identities = 53/164 (32%), Positives = 70/164 (42%), Gaps = 47/164 (28%)
Query: 17 KDENKLSSANGHEERSKKRKKSKSRSRSHERK------------RSKSKERKR--SRDRE 62
+D+ K S R+ K S+SRSRS ERK RS+SKE +R S+D+
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
Query: 63 RKKSKSRE---------------------------RKRSRSKERRRSRSRSRDRRFRGRY 95
KK KS E ++R S+ R SRSRSR+RR R R
Sbjct: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139
Query: 96 RSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVR 139
R K S R + S SR R +S+S R+ K +R
Sbjct: 140 R---ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIR 177
Score = 36.6 bits (83), Expect = 0.058
Identities = 21/74 (28%), Positives = 38/74 (51%)
Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
+K + S + R + R +S++RSRS +RK+ K R+ SR R S R R+
Sbjct: 172 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231
Query: 76 SKERRRSRSRSRDR 89
+ + + + +R +R
Sbjct: 232 AMDAQEALARRLER 245
Score = 33.5 bits (75), Expect = 0.49
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Query: 19 ENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKE 78
E K + RS+ R +++SRSR+ RS+S++RK+ ++ R+ S+S R S
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRT----RSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226
Query: 79 RRRS 82
R R+
Sbjct: 227 RGRN 230
>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
sapiens]
Length = 420
Score = 82.8 bits (203), Expect = 7e-16
Identities = 53/166 (31%), Positives = 88/166 (53%), Gaps = 12/166 (7%)
Query: 144 NLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVD 203
N + ++D +F L+ +DL E+ S G+V D + +D + RS+G +V F D
Sbjct: 139 NASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKD 198
Query: 204 VSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
+SV + L ++ G I + RA A+ KG P +++VG L + +E
Sbjct: 199 AASVDKVLELKEHKLDGKLI-------DPKRAKAL-----KGKEPPKKVFVGGLSPDTSE 246
Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
+ ++ F FG IE+I+L MD++T +G+ FIT++D E KK LE
Sbjct: 247 EQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLE 292
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 80.9 bits (198), Expect = 3e-15
Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)
Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
L + ++ V+ + L+E FS GK V+++ D N + SKG +V +
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241
Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
A+ + G+ + G I V +Q + R A + ++ + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301
Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG +
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359
Query: 318 GRPMKV 323
+P+ V
Sbjct: 360 SKPLYV 365
Score = 75.9 bits (185), Expect = 9e-14
Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
VF L I + L + FS G + +++ D N SKG A+V F + AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158
Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214
Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
SQ + +L+K G +++ +L +I L F FG I S +++ D E
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135
Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G SKGY F+ F E A KA+E++NG L R + VG R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 305 KKALEQLNGFELAGRPMKV 323
++AL+ +N + G+P+++
Sbjct: 66 ERALDTMNFDVIKGKPIRI 84
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 80.9 bits (198), Expect = 3e-15
Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)
Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
L + ++ V+ + L+E FS GK V+++ D N + SKG +V +
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241
Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
A+ + G+ + G I V +Q + R A + ++ + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301
Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG +
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359
Query: 318 GRPMKV 323
+P+ V
Sbjct: 360 SKPLYV 365
Score = 75.9 bits (185), Expect = 9e-14
Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
VF L I + L + FS G + +++ D N SKG A+V F + AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158
Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214
Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
SQ + +L+K G +++ +L +I L F FG I S +++ D E
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135
Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G SKGY F+ F E A KA+E++NG L R + VG R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 305 KKALEQLNGFELAGRPMKV 323
++AL+ +N + G+P+++
Sbjct: 66 ERALDTMNFDVIKGKPIRI 84
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 80.9 bits (198), Expect = 3e-15
Identities = 54/186 (29%), Positives = 91/186 (48%), Gaps = 10/186 (5%)
Query: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
L + ++ V+ + L+E FS GK V+++ D N + SKG +V +
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGFVSYEKH 241
Query: 205 SSVPLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQK------GSAGPMRLYVGSL 257
A+ + G+ + G I V +Q + R A + ++ + LY+ +L
Sbjct: 242 EDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNL 301
Query: 258 HFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELA 317
I ++ LR F PFG I S ++M+ E GRSKG+GF+ FS E A KA+ ++NG +
Sbjct: 302 DDTIDDEKLRKEFSPFGSITSAKVML--EDGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359
Query: 318 GRPMKV 323
+P+ V
Sbjct: 360 SKPLYV 365
Score = 75.9 bits (185), Expect = 9e-14
Identities = 48/178 (26%), Positives = 92/178 (51%), Gaps = 8/178 (4%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
VF L I + L + FS G + +++ D N SKG A+V F + AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158
Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
G + + V ++ K R A + ++ + +Y+ + + ++ L+ +F F
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT----NVYIKNFGEEVDDESLKELFSQF 214
Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G+ S+++M D G+SKG+GF+++ E A KA+E++NG E++G+ + VG ++ +
Sbjct: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 13/164 (7%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVL-GVPIIVQA 227
L E FS G V +R+ D +RRS G AYV F + A+ V+ G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 228 SQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSET 287
SQ + +L+K G +++ +L +I L F FG I S +++ D E
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-EN 135
Query: 288 GRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTD 331
G SKGY F+ F E A KA+E++NG L R + VG R +
Sbjct: 136 G-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 246 SAGPMR-LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECA 304
S+ PM LYVG LH ++TE ML F P G + SI++ D T RS GY ++ F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 305 KKALEQLNGFELAGRPMKV 323
++AL+ +N + G+P+++
Sbjct: 66 ERALDTMNFDVIKGKPIRI 84
>gi|20373175 musashi 2 isoform a [Homo sapiens]
Length = 328
Score = 80.5 bits (197), Expect = 3e-15
Identities = 46/161 (28%), Positives = 79/161 (49%), Gaps = 8/161 (4%)
Query: 149 ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVP 208
+ D +F L+ + P L ++FS G++R+ ++ D ++RS+G +V F D +SV
Sbjct: 17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75
Query: 209 LAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRG 268
+VLG P S+ + A K +++VG L N + ++
Sbjct: 76 -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128
Query: 269 IFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
FE FG++E LM D T R +G+GF+TF + + +K E
Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 169
Score = 55.5 bits (132), Expect = 1e-07
Identities = 26/80 (32%), Positives = 40/80 (50%)
Query: 231 EKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRS 290
E N + + + P ++++G L + + D LR F FG I +M D T RS
Sbjct: 2 EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61
Query: 291 KGYGFITFSDSECAKKALEQ 310
+G+GF+TF+D K L Q
Sbjct: 62 RGFGFVTFADPASVDKVLGQ 81
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 79.7 bits (195), Expect = 6e-15
Identities = 50/194 (25%), Positives = 101/194 (52%), Gaps = 8/194 (4%)
Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
Query: 208 PLAIG-LTGQRVLGVPIIVQ----ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNIT 262
A+ + G++++G + V S +K+ +++ + Q+ S ++VG L IT
Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR-SQDHFHVFVGDLSPEIT 118
Query: 263 EDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
+ ++ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
Query: 323 VGHVTERTDASSAS 336
T + A ++
Sbjct: 179 TNWATRKPPAPKST 192
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/188 (25%), Positives = 83/188 (44%), Gaps = 17/188 (9%)
Query: 146 TPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVS 205
T +D VF L+ I D++ F+ G++ D R++ D + +SKG +V F +
Sbjct: 99 TQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKW 158
Query: 206 SVPLAIGLTGQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYV 254
AI G + LG P +++ + + + + S +Y
Sbjct: 159 DAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC 218
Query: 255 GSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGF 314
G + +TE ++R F PFG+I I++ D KGY F+ F+ E A A+ +NG
Sbjct: 219 GGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGT 272
Query: 315 ELAGRPMK 322
+ G +K
Sbjct: 273 TIEGHVVK 280
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 79.3 bits (194), Expect = 8e-15
Identities = 48/190 (25%), Positives = 97/190 (51%), Gaps = 11/190 (5%)
Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
E+ +T++ L+ + + + FS +G ++ +MI D + + +VEF +
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
A+ + G++++G + K A ++ +K ++ ++VG L IT + +
Sbjct: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111
Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
+ F PFGRI +++ D TG+SKGYGF++F + A+ A++Q+ G L GR ++
Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171
Query: 327 TERTDASSAS 336
T + A ++
Sbjct: 172 TRKPPAPKST 181
Score = 70.5 bits (171), Expect = 4e-12
Identities = 46/179 (25%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
VF L+ I D++ F+ G++ D R++ D + +SKG +V F + AI
Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
G + LG P +++ + + + + S +Y G + +TE
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMK 322
++R F PFG+I I++ D KGY F+ F+ E A A+ +NG + G +K
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 79.3 bits (194), Expect = 8e-15
Identities = 56/184 (30%), Positives = 90/184 (48%), Gaps = 13/184 (7%)
Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
E TV+ L ++ L E F G V + M DR + + +G +VEF+
Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
Query: 208 PLAIGLTGQ-RVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
AI + ++ G PI V N+A+A NL G+ +++G+L I E +L
Sbjct: 68 DYAIKIMNMIKLYGKPIRV-------NKASAHNKNLDVGA----NIFIGNLDPEIDEKLL 116
Query: 267 RGIFEPFGRI-ESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH 325
F FG I ++ ++M D +TG SKGY FI F+ + + A+E +NG L RP+ V +
Sbjct: 117 YDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSY 176
Query: 326 VTER 329
++
Sbjct: 177 AFKK 180
>gi|25121993 musashi 2 isoform b [Homo sapiens]
Length = 251
Score = 79.0 bits (193), Expect = 1e-14
Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 8/155 (5%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
+F L+ + P L ++FS G++R+ ++ D ++RS+G +V F D +SV
Sbjct: 19 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71
Query: 215 GQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFG 274
+VLG P S+ + A K +++VG L N + ++ FE FG
Sbjct: 72 -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130
Query: 275 RIESIQLMMDSETGRSKGYGFITFSDSECAKKALE 309
++E LM D T R +G+GF+TF + + +K E
Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/60 (38%), Positives = 34/60 (56%)
Query: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
++++G L + + D LR F FG I +M D T RS+G+GF+TF+D K L Q
Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77
Score = 34.7 bits (78), Expect = 0.22
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 153 RTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
+ +F L+A D++++F GKV D ++ D+ + R +G +V F
Sbjct: 106 KKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 154
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 78.6 bits (192), Expect = 1e-14
Identities = 65/195 (33%), Positives = 90/195 (46%), Gaps = 33/195 (16%)
Query: 12 EAPYKKDENKLSSANGHEERS-KKRKKSKSRSRSHE-RKRSKSKERKRSRDRERKKSKSR 69
E Y + E++ +S +G S K + + +RSRS E +RS+SK R RS R R + SR
Sbjct: 6 EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65
Query: 70 ERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKS 129
R +RS+ R RS RSR R + YR RR S S S
Sbjct: 66 -RHYTRSRSRSRSHRRSRSRSYSRDYR-------------------------RRHSHSHS 99
Query: 130 PFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRN 189
P + R + P+ VF + L RDL E FS G + DV ++ D+
Sbjct: 100 PMSTRR---RHVGNRANPDPNCCLGVFGLSLYT--TERDLREVFSKYGPIADVSIVYDQQ 154
Query: 190 SRRSKGIAYVEFVDV 204
SRRS+G A+V F +V
Sbjct: 155 SRRSRGFAFVYFENV 169
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/72 (37%), Positives = 43/72 (59%)
Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
L V L TE LR +F +G I + ++ D ++ RS+G+ F+ F + + AK+A E+
Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179
Query: 312 NGFELAGRPMKV 323
NG EL GR ++V
Sbjct: 180 NGMELDGRRIRV 191
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 77.8 bits (190), Expect = 2e-14
Identities = 48/198 (24%), Positives = 99/198 (50%), Gaps = 11/198 (5%)
Query: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
++ RT++ L+ + + + FS +G + +MI++ S + +VEF +
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61
Query: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
A+ + G+++LG + K A ++ +K ++ ++VG L IT + +
Sbjct: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113
Query: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
+ F PFG+I +++ D TG+SKGYGF++F + A+ A+ + G L GR ++
Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173
Query: 327 TERTDASSASSFLDSDEL 344
T + A ++ ++ +L
Sbjct: 174 TRKPPAPKSTQENNTKQL 191
Score = 72.4 bits (176), Expect = 9e-13
Identities = 58/231 (25%), Positives = 98/231 (42%), Gaps = 23/231 (9%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
VF L+ I D++ F+ GK+ D R++ D + +SKG +V F + AI
Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
Query: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
G + LG P +++Q + + + + S +Y G + +T+
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
Query: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
++R F PFG+I I++ + KGY F+ FS E A A+ +NG + G +K
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC 272
Query: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRL-QLMARLAEGTGLQIPP 373
E D + +D + + G + Q MA G Q+PP
Sbjct: 273 YWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMA-----NGWQVPP 318
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 76.6 bits (187), Expect = 5e-14
Identities = 45/171 (26%), Positives = 85/171 (49%), Gaps = 8/171 (4%)
Query: 141 PIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVE 200
P++ E+ R +F L+ L ++ GK+ D ++ D S+RS+G +V
Sbjct: 9 PLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVT 68
Query: 201 FVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMR-LYVGSLHF 259
F ++ V A+ P + E RA A + + G+ ++ L+VG +
Sbjct: 69 FSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKE 121
Query: 260 NITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
+ E LR FE +G+I++I+++ D ++G+ +G+GF+TF D + K + Q
Sbjct: 122 DTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQ 172
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 76.3 bits (186), Expect = 7e-14
Identities = 56/185 (30%), Positives = 95/185 (51%), Gaps = 13/185 (7%)
Query: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-LTGQRVLGVPIIVQA 227
L++ F G V++++D S +SKG +V F A+ + G+ + G I V
Sbjct: 207 LKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGR 265
Query: 228 SQAEKNRAAAMANNLQKGSAGPM------RLYVGSLHFNITEDMLRGIFEPFGRIESIQL 281
+Q + R + ++ + LYV +L I ++ LR F PFG I S ++
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKV 325
Query: 282 MMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDS 341
MM E GRSKG+GF+ FS E A KA+ ++NG +A +P+ V + +R + A +L +
Sbjct: 326 MM--EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA-LAQRKEERQA--YLTN 380
Query: 342 DELER 346
+ ++R
Sbjct: 381 EYMQR 385
Score = 74.3 bits (181), Expect = 2e-13
Identities = 52/194 (26%), Positives = 97/194 (50%), Gaps = 16/194 (8%)
Query: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIG-L 213
+F L I + L + S G + ++ D N SKG +V F + AI +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158
Query: 214 TGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPF 273
G + G + V ++ K R A + ++ +Y+ + ++ ++ L+ +F F
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFP----NVYIKNFGEDMDDERLKDLFGKF 214
Query: 274 GRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDAS 333
G S+++M D E+G+SKG+GF++F E A+KA++++NG EL G+ + VG ++ +
Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273
Query: 334 SASSFLDSDELERT 347
+ EL+RT
Sbjct: 274 T--------ELKRT 279
Score = 53.9 bits (128), Expect = 3e-07
Identities = 27/72 (37%), Positives = 43/72 (59%)
Query: 252 LYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQL 311
LYVG LH ++TE ML F P G I SI++ D T S Y ++ F ++ A+ AL+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 312 NGFELAGRPMKV 323
N + G+P+++
Sbjct: 73 NFDVIKGKPVRI 84
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 75.9 bits (185), Expect = 9e-14
Identities = 52/142 (36%), Positives = 80/142 (56%), Gaps = 7/142 (4%)
Query: 16 KKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSR 75
+++E + A E R + R +S+ SR+ +R+ S+S++ KRSR RER++S+SR+R+RSR
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 76 SKER--RRSRSRSRD-RRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFR 132
S +R R+ RSRSRD RR + R R Y K S R + S + +R S K
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSY---KHRSKSRDREQDRKSKEKEKRGSDDKKSSV 391
Query: 133 KDKSPVREPID-NLTPEERDAR 153
K S ++ D N +E D +
Sbjct: 392 KSGSREKQSEDTNTESKESDTK 413
Score = 72.8 bits (177), Expect = 7e-13
Identities = 48/137 (35%), Positives = 74/137 (54%), Gaps = 14/137 (10%)
Query: 12 EAPYKKDENKLSSANGHEERSKKR---KKSKSRSRSHERKRSKSKERKRSRDRERKKSKS 68
E +++E + EER K+R ++ + RSRS R S++ +R+ SR R+ K+S+S
Sbjct: 260 EREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRS 319
Query: 69 RERKRSRSKERRRSRSRSR-DRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRS 127
RER+RSRS++RRRSRS R +R+ R R R + S R + H R +SR
Sbjct: 320 RERRRSRSRDRRRSRSHDRSERKHRSRSRD-----RRRSKSRDRKSYKH-----RSKSRD 369
Query: 128 KSPFRKDKSPVREPIDN 144
+ RK K + D+
Sbjct: 370 REQDRKSKEKEKRGSDD 386
Score = 60.1 bits (144), Expect = 5e-09
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
Query: 25 ANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRS 84
A E + K RK+++ R K+ K + +R ++RER++ + ++R +ER + R+
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284
Query: 85 RSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRK 133
R R+RR R R RS +S S R H SR R RS+S R+
Sbjct: 285 RDRERRKRSRSRSRHSSR--TSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Score = 55.8 bits (133), Expect = 9e-08
Identities = 49/161 (30%), Positives = 81/161 (50%), Gaps = 15/161 (9%)
Query: 7 IEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKS 66
I+A +E +K + + E K++++ + R + ER+R + + ++R + ER+K
Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Query: 67 KSRE---RKRSRSKERRRSR------SRSRD-RRFRGR-YRSPYSGPKFNSAIRGKIGLP 115
++R+ RKRSRS+ R SR SRSRD +R R R R S + S +
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 116 HSIKLSRRRSRSKSPFRKD---KSPVREPIDNLTPEERDAR 153
H + SR R RSKS RK +S R+ + +E++ R
Sbjct: 343 HRSR-SRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKR 382
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,617,437
Number of Sequences: 37866
Number of extensions: 755854
Number of successful extensions: 22020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 679
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 6519
Number of HSP's gapped (non-prelim): 6449
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.