BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] (1250 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47132519 Ras association and pleckstrin homology domains 1 is... 2551 0.0 gi|42740893 Ras association and pleckstrin homology domains 1 is... 1148 0.0 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 477 e-134 gi|160707881 formin 2 [Homo sapiens] 194 6e-49 gi|163965366 nascent polypeptide-associated complex alpha subuni... 174 5e-43 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 169 2e-41 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 168 3e-41 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 168 3e-41 gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] 159 2e-38 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 159 2e-38 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 159 2e-38 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 158 3e-38 gi|116284392 mucin 2 precursor [Homo sapiens] 155 2e-37 gi|48762697 growth factor receptor-bound protein 10 isoform c [H... 152 2e-36 gi|48762695 growth factor receptor-bound protein 10 isoform c [H... 152 2e-36 gi|48762679 growth factor receptor-bound protein 10 isoform a [H... 152 2e-36 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 150 6e-36 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 144 5e-34 gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] 143 1e-33 gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] 143 1e-33 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 142 2e-33 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 141 4e-33 gi|110349719 titin isoform N2-A [Homo sapiens] 137 5e-32 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 137 6e-32 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 136 1e-31 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 136 1e-31 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 136 1e-31 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 129 1e-29 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 127 7e-29 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 126 1e-28 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 2551 bits (6613), Expect = 0.0 Identities = 1250/1250 (100%), Positives = 1250/1250 (100%) Query: 1 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET 60 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET Sbjct: 1 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET 60 Query: 61 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK 120 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK Sbjct: 61 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK 120 Query: 121 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK 180 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK Sbjct: 121 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK 180 Query: 181 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ 240 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ Sbjct: 181 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ 240 Query: 241 PITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNL 300 PITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNL Sbjct: 241 PITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNL 300 Query: 301 MDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALF 360 MDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALF Sbjct: 301 MDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALF 360 Query: 361 KNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLL 420 KNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLL Sbjct: 361 KNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLL 420 Query: 421 RASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQ 480 RASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQ Sbjct: 421 RASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQ 480 Query: 481 YIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSS 540 YIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSS Sbjct: 481 YIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSS 540 Query: 541 SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNR 600 SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNR Sbjct: 541 SSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNR 600 Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660 Query: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780 Query: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840 Query: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900 Query: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960 Query: 961 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP Sbjct: 961 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020 Query: 1021 PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPET 1080 PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPET Sbjct: 1021 PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPET 1080 Query: 1081 ELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISE 1140 ELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISE Sbjct: 1081 ELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISE 1140 Query: 1141 QPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDM 1200 QPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDM Sbjct: 1141 QPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDM 1200 Query: 1201 ALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW 1250 ALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW Sbjct: 1201 ALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW 1250 >gi|42740893 Ras association and pleckstrin homology domains 1 isoform 3 [Homo sapiens] Length = 644 Score = 1148 bits (2969), Expect = 0.0 Identities = 592/644 (91%), Positives = 592/644 (91%), Gaps = 52/644 (8%) Query: 1 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET 60 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET Sbjct: 1 MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQET 60 Query: 61 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK 120 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK Sbjct: 61 NMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQK 120 Query: 121 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK 180 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK Sbjct: 121 LPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTK 180 Query: 181 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ 240 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ Sbjct: 181 PLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQ 240 Query: 241 PITE----------------------------------------------------EEQA 248 PITE EEQA Sbjct: 241 PITEHAISLRCSSKQAKRHIDFTEEQAELTPHSYLDRETSLLLRNIAGKPSHLLTKEEQA 300 Query: 249 AKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGY 308 AKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGY Sbjct: 301 AKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGY 360 Query: 309 SLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLL 368 SLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLL Sbjct: 361 SLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLL 420 Query: 369 GKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYV 428 GKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYV Sbjct: 421 GKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYV 480 Query: 429 PKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCD 488 PKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCD Sbjct: 481 PKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCD 540 Query: 489 DVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQS 548 DVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQS Sbjct: 541 DVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQS 600 Query: 549 NHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSK 592 NHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSK Sbjct: 601 NHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSK 644 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 477 bits (1227), Expect = e-134 Identities = 273/635 (42%), Positives = 363/635 (57%), Gaps = 93/635 (14%) Query: 155 DVTAQLEQASLSMDEAAQQSVLEDTKPLVTNQHRRTASAGTVSDAEVHSISNSSHSSITS 214 D+ A + + EA Q+++ + L H + A S A S+ ++ + T Sbjct: 63 DLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAA--SLGYGTNVAATG 120 Query: 215 AASSMDSLDIDKVTRPQELDLTHQG-QPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVI 273 + D L +L L +P+++EE+ A+ KA+KI++ALEK+KEA+VKKLV+ Sbjct: 121 ISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVV 180 Query: 274 RVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENL 333 +VHM+D+S+K++MVDERQ R VLDNL +K+HC ++DW L E ELQ+ER FEDHEN+ Sbjct: 181 KVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENV 240 Query: 334 VENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLL---GKKETAE----MADRNKEVLLE 386 VE L +WTRD++NK++F+E+ EKYA+FKNPQN+ L GKKE+ E M +NKE LLE Sbjct: 241 VEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLE 300 Query: 387 ECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLD 446 E FCG+S+ VPE+EG L+LK+DGKKSWK+RYFLLRASGIYYVPKGK K SRDL CF+Q + Sbjct: 301 ESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFE 360 Query: 447 HVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYG 506 +VN+YYG ++ KYKAPTDYC VLKHPQIQK+SQYIKYLCCDD RTL+QWV GIRIAKYG Sbjct: 361 NVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYG 420 Query: 507 KQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGH 566 K LY NYQ A+ + A WT+L + + + + S+ P++ TQP G Sbjct: 421 KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKT------------GTTQPNGQ 468 Query: 567 V-RSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTP------- 618 + ++ VS+V EA + E+SK + ++ + VP PK P Sbjct: 469 IPQATHSVSAVLQEAQRHA----ETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRR 524 Query: 619 --YTASQPSPP----------LPPPP----PPPPPPPP---PPPPPPPPLPSQSAPSAGS 659 T+ P+ P LP PP PPPPPPPP P PPPPP + P Sbjct: 525 SSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPD--- 581 Query: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPP 719 F PP PP + +PPPPPPPP P Sbjct: 582 ------------------------FVPPPPPSYAGIA---------GSELPPPPPPPPAP 608 Query: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQH 754 P +P P P P PP + H Sbjct: 609 APAPVPDSARPPPAVAKRP----PVPPKRQENPGH 639 Score = 79.0 bits (193), Expect = 3e-14 Identities = 67/235 (28%), Positives = 91/235 (38%), Gaps = 59/235 (25%) Query: 771 APLPPQAPPKPLVTIP---APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827 AP P PK T P P +T +V+ V+ +A T K+PA + P Sbjct: 450 APAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSK----DKKPALGNHHDPAV 505 Query: 828 PPTPPVP---VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ----FPPPPTPPAMES 880 P P P +PPP ++ S + P +PL + + + PPPP PP ++ Sbjct: 506 PRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDD 565 Query: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV----- 935 P+ PP P PDF PPP+ PPPPPS Sbjct: 566 -----------PELPP---------------PPPDFMEPPPD---FVPPPPPSYAGIAGS 596 Query: 936 ---PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987 P PPPPP P +P PD + P K+PP P+R + GA Sbjct: 597 ELPPPPPPPPAPAPAPVPDSARPP--------PAVAKRPPVPPKRQENPGHPGGA 643 Score = 63.9 bits (154), Expect = 9e-10 Identities = 63/247 (25%), Positives = 79/247 (31%), Gaps = 66/247 (26%) Query: 648 PLPSQSAPSAGSAAPMF----VKYSTITRLQNASQHSG-ALFKPPTPPVMQSQSVKPQIL 702 P + P G+ P +S LQ A +H+ + K P +V Sbjct: 451 PAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPH 510 Query: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA----PSLPQFSAPPPPLKIHQVQHITQV 758 P + + PPPP T GS LK P+ P PPPP Sbjct: 511 APKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPP------------ 558 Query: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818 PP P P +P P P P PP PP PP+ Sbjct: 559 -PPPPLDDPELPPPPPDFMEP-----------------------PPDFVPPPPPS--YAG 592 Query: 819 FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878 S +PP PP PP P P P P P P+V K+ PP PP Sbjct: 593 IAGSELPPPPPPPPAPAPAPV------------PDSARPPPAVAKR-------PPVPPKR 633 Query: 879 ESQPLKP 885 + P P Sbjct: 634 QENPGHP 640 Score = 57.8 bits (138), Expect = 6e-08 Identities = 34/75 (45%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Query: 19 KEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEAL 78 + +D+D+MF LGE+D LTQSL D P P A F+Y +LNE+L Sbjct: 3 ESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPP------RAEFNYSVGFKDLNESL 56 Query: 79 NQGETVDLDALMADL 93 N E DLDALMADL Sbjct: 57 NALEDQDLDALMADL 71 Score = 57.0 bits (136), Expect = 1e-07 Identities = 62/230 (26%), Positives = 95/230 (41%), Gaps = 31/230 (13%) Query: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLVSKFTPPAESGSP 1013 S G KT T+ P G+ P T ++ ++ + AE + K+P++ + P A Sbjct: 455 STGPKTG-TTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAP- 512 Query: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF 1073 K +LPPP PP + SG KA G G P+PP D Sbjct: 513 -KSSLPPP--PPVRRSSDTSG--------SPATPLKAKGTGGGG------LPAPPDDFLP 555 Query: 1074 PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKR------ 1127 PPPPP PL E+P P V P P ++ ++ + PPP P Sbjct: 556 PPPPP---PPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAP 612 Query: 1128 -NDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176 DS R A ++++P + + P P + + F++DL + LQ+K Sbjct: 613 VPDSARPPPA-VAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQKK 661 Score = 37.4 bits (85), Expect = 0.090 Identities = 40/166 (24%), Positives = 60/166 (36%), Gaps = 39/166 (23%) Query: 1096 NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT----VVPQV 1151 +T PK P Q + +A ++ R + ++P + VP+ Sbjct: 455 STGPKTGTTQPNGQ------IPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRA 508 Query: 1152 PTSPKSSLSVQPGFLADLNRT------LQRKSITRHGSLSSR----MSRAEPTATMDDMA 1201 P +PKSSL P + + L+ K T G L + + P +DD Sbjct: 509 PHAPKSSLPPPPPVRRSSDTSGSPATPLKAKG-TGGGGLPAPPDDFLPPPPPPPPLDDPE 567 Query: 1202 LPPPPPELLS---------DQQKAGYGGSHISGYATLRRGPPPAPP 1238 LPPPPP+ + AG GS + PPP PP Sbjct: 568 LPPPPPDFMEPPPDFVPPPPPSYAGIAGSEL---------PPPPPP 604 Score = 32.3 bits (72), Expect = 2.9 Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 3/34 (8%) Query: 928 PPPPPSPV---PAPPPPPPPTASPTPDKSGSPGK 958 PPPP PV P PPPPP P + + K Sbjct: 129 PPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADK 162 Score = 31.2 bits (69), Expect = 6.5 Identities = 13/23 (56%), Positives = 14/23 (60%), Gaps = 2/23 (8%) Query: 915 DFPPPP--PESSLVFPPPPPSPV 935 D PPPP P L PPPPP P+ Sbjct: 127 DLPPPPADPVLDLPLPPPPPEPL 149 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 194 bits (492), Expect = 6e-49 Identities = 148/433 (34%), Positives = 172/433 (39%), Gaps = 85/433 (19%) Query: 597 SMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPP------PPPPPPPPP---PPPP 647 S + P +VPP P P + + PS +P PPP PPPPPP P PPPP Sbjct: 867 SSSMPGLGMVPP--PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924 Query: 648 PLPSQS------APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQI 701 PLP P AG P + + I PP PP+ + P Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAI---------------PPPPPLPGAGIPLPPP 969 Query: 702 LVPPNGVVPPPPP------PPPPPTPGSAMAQLKPAPCA-----PSLPQFSAPPPPLKIH 750 L P +PPPPP PPPPP PG+ + P P A P LP PPPP Sbjct: 970 L--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---- 1023 Query: 751 QVQHITQVAPPTP------PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP 804 + PP P PPPPP+P P PP P IP P P+ PP Sbjct: 1024 -PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP------PPLPGAGIPP 1076 Query: 805 TPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ 864 P P P P + IPP PP P V +PPP P + PPP P + +P Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPL 1135 Query: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPP----AVKAKPKWQPSSIPVPSP----DF 916 + PPPP P + P P+P P PP + P IP P P Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195 Query: 917 PPPPPESSLVFPPPPP------SPVPAPPPPPPPTASPTP---DKSGSP-----GKKTSK 962 PPPPP PPPPP P PAPP PPP T P P SG P G T Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255 Query: 963 TSSPGGKKPPPTP 975 T G PPP P Sbjct: 1256 TPQVCGFLPPPLP 1268 Score = 188 bits (478), Expect = 2e-47 Identities = 179/626 (28%), Positives = 216/626 (34%), Gaps = 188/626 (30%) Query: 609 LSPQPKIVTPYTASQPSPPLPPPPPPP--------------------------------- 635 +SP+ +I + QP+ + PPPPP Sbjct: 789 VSPR-RISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSS 847 Query: 636 --------PPPPPPP--------------PPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673 P PPP P PPPPPPLP + P+ S T + Sbjct: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPS-----------TAI 896 Query: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP-----PPPPPPTPGSAMAQL 728 G PP PP + + P +P G++P PP PPPPP PG+A+ Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956 Query: 729 KPAPCA-----PSLPQFSAPPPPLKIHQVQHITQVAPPTP----PPPPPIPAPLPPQAPP 779 P P A P LP PPP PP P PPPPP+P P PP Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPP--------------PPLPGAGIPPPPPLPGAGIPPPPP 1002 Query: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT 839 P IP P P+ PP P P P P + IPP PP P +PPP Sbjct: 1003 LPGAGIPPP------PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056 Query: 840 LPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVK 899 P + PPP P + +P + PPPP P P P+P P PP Sbjct: 1057 -PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115 Query: 900 AKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959 A P P+P PPPPP PPPPP P PPPPP Sbjct: 1116 A---GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP---------------- 1156 Query: 960 TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019 PG PPP P + I P P P V G P LP Sbjct: 1157 -----LPGAGIPPPPPLPGAGIP-------PPPPLPGV-------------GIPPPPPLP 1191 Query: 1020 PPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE 1079 PP P L G +P P L G G P PP + PPPP Sbjct: 1192 GVGIPPPP---PLPGAGIP----------PPPPLPGMGIPPAPAPPLPPPGTGIPPPP-- 1236 Query: 1080 TELPL--PPIEIPAVFSGN-TSPKVAVVNPQP---------QQWSKMSVKKAPPPTRP-- 1125 LP+ PP+ +P V S +P+V P P K S K+ P RP Sbjct: 1237 -LLPVSGPPL-LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMK 1294 Query: 1126 -----------KRNDSTRLTQAEISE 1140 KR+ ST L +I E Sbjct: 1295 PLYWTRIQLHSKRDSSTSLIWEKIEE 1320 Score = 126 bits (317), Expect = 1e-28 Identities = 145/578 (25%), Positives = 184/578 (31%), Gaps = 150/578 (25%) Query: 634 PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693 PP P PP PP S S + V I+ ++ Q + ++ +PP PP + Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817 Query: 694 SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA---PPPPLKIH 750 + + Q P PP S Q S + S PPPL Sbjct: 818 WSAGQGQ-------------PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864 Query: 751 QVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810 + PPPPPP+P P P + P T+ + P PP P + Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP----PPPPLPGAGI 920 Query: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870 PP P P + I P PP P +PP PPP P + +P P Sbjct: 921 PPP---PPLPGAGILPLPPLPGAGIPP------------PPPLPGAAIP----------P 955 Query: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930 PPP P A P P+P P PP A P P+P PPPPP PPP Sbjct: 956 PPPLPGAGIPLP-PPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPP 1011 Query: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS-PGGKKPPPTPQRNSSIKSSSGAEH 989 PP P PPPPP + P PG PG PPP P + I Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP------- 1064 Query: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049 P P P + P +G P LP PP P L GV +P Sbjct: 1065 PPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGVGIP----------P 1109 Query: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109 P L G G + P P + PPPPP LP IP Sbjct: 1110 PPPLPGAG----IPPPPPLPGAGIPPPPP-----LPGAGIP------------------- 1141 Query: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADL 1169 PPP P+ +P P P + + P Sbjct: 1142 ----------PPPPLPRVG-------------------IPPPPPLPGAGIPPPPPLPG-- 1170 Query: 1170 NRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207 + P + + +PPPPP Sbjct: 1171 -------------------AGIPPPPPLPGVGIPPPPP 1189 Score = 45.1 bits (105), Expect = 4e-04 Identities = 75/320 (23%), Positives = 106/320 (33%), Gaps = 64/320 (20%) Query: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS-----------PGKKTSKTSSPGG 968 P E V PP +P PP PP S K S + S + Sbjct: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSI 807 Query: 969 KKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028 +PPP P S+ S+G P + P S + + S K + P+ PP P Sbjct: 808 SQPPPPP----SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP- 862 Query: 1029 KLNLSGVNLPGVLQQGCVSAKAPVLSG-----------------RGKDSVVEFPSPPSDS 1071 S ++PG+ G V P L G +G + + P P + Sbjct: 863 -CTESSSSMPGL---GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918 Query: 1072 DFPPPPP---ETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128 PPPPP LPLPP+ + P A+ P P + + + PPP Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL---PPP------ 969 Query: 1129 DSTRLTQAEISEQPTM-ATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSR 1187 L A I P + +P P P + + P L I L Sbjct: 970 ----LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--------PLPGAGIPPPPPLPG- 1016 Query: 1188 MSRAEPTATMDDMALPPPPP 1207 + P + +PPPPP Sbjct: 1017 -AGIPPPPPLPGAGIPPPPP 1035 Score = 40.0 bits (92), Expect = 0.014 Identities = 68/270 (25%), Positives = 91/270 (33%), Gaps = 77/270 (28%) Query: 959 KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH-PEPKRPSVDSLV---SKFTPPAESGSPS 1014 +TS T G PP GAE P+ K S SL+ + + +S P+ Sbjct: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804 Query: 1015 KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVE----FPSPP-- 1068 + PP P P L +G PG +S + S + PSPP Sbjct: 805 QSISQPP---PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861 Query: 1069 ----SDSDFP-----PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119 S S P PPPP PLP + +P T P A+ P P Q ++M Sbjct: 862 PCTESSSSMPGLGMVPPPPP---PLPGMTVP------TLPSTAIPQPPPLQGTEM----L 908 Query: 1120 PPPTRPKRNDSTRLTQAEISEQPTM--ATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKS 1177 PPP P L A I P + A ++P P PG Sbjct: 909 PPPPPP-------LPGAGIPPPPPLPGAGILPLPPL---------PG------------- 939 Query: 1178 ITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207 + P + A+PPPPP Sbjct: 940 -----------AGIPPPPPLPGAAIPPPPP 958 Score = 36.6 bits (83), Expect = 0.15 Identities = 47/190 (24%), Positives = 69/190 (36%), Gaps = 34/190 (17%) Query: 851 PPSPLSPVPSVVKQI----------ASQFP-PPPTPPAMESQPLKPVPANVA-----PQS 894 PP+ +SP P + A + P P T A+ + L +P ++A PQ Sbjct: 235 PPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSA--LSDLPESLAAEPREPQQ 292 Query: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954 PP+ P + S+P P P SS FP P P P A T ++ Sbjct: 293 PPSPGGLPVSEAPSLPAAQPAAKDSP--SSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGE 350 Query: 955 SPGKKTSKTSSPGGKKPP----PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAES 1010 + + SPG + P PQR E PE + D+ + P S Sbjct: 351 EDAFEDAPRGSPGEEWAPEVGEDAPQRL--------GEEPEEEAQGPDAPAAASLP--GS 400 Query: 1011 GSPSKETLPP 1020 +PS+ P Sbjct: 401 PAPSQRCFKP 410 Score = 31.2 bits (69), Expect = 6.5 Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 10/89 (11%) Query: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEPKRPS 996 P PP SP P + S G+ P P T Q S++ + EP+ P Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291 Query: 997 VDSLVSKFTPPAESGSPSKETLPPPAAPP 1025 PP+ G P E PAA P Sbjct: 292 --------QPPSPGGLPVSEAPSLPAAQP 312 Score = 30.8 bits (68), Expect = 8.5 Identities = 53/232 (22%), Positives = 71/232 (30%), Gaps = 51/232 (21%) Query: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF 740 GA P +P Q+ S + P + P P PP+PG P APSLP Sbjct: 259 GAGEAPGSPDTEQALSALSDL---PESLAAEPREPQQPPSPGGL-----PVSEAPSLP-- 308 Query: 741 SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP---------QAPPKPLVTIPAPTST 791 A P K + A P P P A P + P + Sbjct: 309 -AAQPAAK----DSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPG 363 Query: 792 KTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851 + AP V + AP + P PA+ P P P C KP Sbjct: 364 EEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP------------SQRCFKPY 411 Query: 852 PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903 P P +K Q P P+ +P P +K +P+ Sbjct: 412 P---LITPCYIKTTTRQLSSPNHSPSQ------------SPNQSPRIKRRPE 448 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 174 bits (441), Expect = 5e-43 Identities = 195/726 (26%), Positives = 258/726 (35%), Gaps = 173/726 (23%) Query: 528 SLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAG------HVRSQSIVSSVFSE-- 579 SLS K +++ P S + S V+ P G + S+V+ F + Sbjct: 840 SLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899 Query: 580 ----AWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPP- 634 A K+ L +S + ++ P +P SP PK P+PP PP P Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPA-SPSPK-------GAPTPPAATPPSPK 951 Query: 635 -PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693 P P P P PP + +P G A P GA PTPP Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATP---------------SPKGA----PTPPAAT 992 Query: 694 SQSVKPQILVP-PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752 S K P P G PP PP P K +P A P+ ++ PP Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSP---------KGSPAATPFPKGASTPP------- 1036 Query: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP- 811 A P P P PLP AP P T+P+P + PP TPP P Sbjct: 1037 -----AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091 Query: 812 -----PAKKQPAFPASYIPPSP----PTPP----VPVPPPTLPKQQSFCAKPPP--SPLS 856 P+ K P + PPSP TPP P T P + A PPP +P + Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151 Query: 857 PVPSVVKQIASQFPPPP---------TPPAMESQPLKPVPANVAPQSPPAVKAKPKW--- 904 P + PPP TPP+ + P P AP +P A PK Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLA 1210 Query: 905 --QPSSIPVPSPDFPPPPPESSLVFPPP---PPSPVPAPPPP------PPPTASPTPDKS 953 P P +P PP P+ L P P P +P PP P PPP +PTP + Sbjct: 1211 TPSPKGAPT-TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269 Query: 954 GSPGKKTSKTSSP--GGKKP----PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007 P K + P G P PP+P+ + GA P TPP Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-----------TPP 1318 Query: 1008 AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067 + GSP T PP AP P V P +G + A S +G P+ Sbjct: 1319 SPKGSPG--TPPPKGAPTPP------AVTPPS--PKGTPTLPATTPSSKGG------PTT 1362 Query: 1068 PSDSDFPPPPPETE--------LPLPPIEIPAVFSGN---TSPKVAVVNPQ--------- 1107 PS + P PP T P P PA+ S TSP V ++P+ Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422 Query: 1108 ------------PQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 P + +S+KKAP + PK +T ++ + PT+ V P P P Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD----PTLPAVTPPSPKEP 1478 Query: 1156 KSSLSV 1161 + V Sbjct: 1479 PAPKQV 1484 Score = 164 bits (415), Expect = 5e-40 Identities = 196/760 (25%), Positives = 258/760 (33%), Gaps = 104/760 (13%) Query: 532 SSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESS 591 SS S +S +PE+ + DS + P + S + +G L Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884 Query: 592 KARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP---PPPPPPPPPPPPP 648 +N P+ P +P PK + + SP P P P P P P PP Sbjct: 885 TPTPSVVNLPFPK-EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943 Query: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP-PNG 707 + +P G A P K++ PTPP S K P P G Sbjct: 944 AATPPSPKGGPATPS-PKWA------------------PTPPAATPPSPKGGPATPSPKG 984 Query: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767 PP PP P G A K AP P++ S P + + TPP P Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044 Query: 768 PIPA--PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825 PA PLP AP P T+P+P + PP TPP P K PA P+ Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP--KGGPATPSPKGA 1102 Query: 826 PSPP--TPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP---PTPPAMES 880 P PP TPP P P + P +P SP + PPP PT PA Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT------PPPKGAPTTPA--- 1153 Query: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV-PAPP 939 P SP A P P P +P PP P+ L P P +P PA Sbjct: 1154 ---------ATPPSPKGGLATPP--PKGAPT-TPAATPPSPKGGLATPSPKGAPTTPAAT 1201 Query: 940 PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDS 999 PP P TP G+P + SP G P+P+ ++ A P PK Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK---GAPTTPAATPPSPKG----- 1253 Query: 1000 LVSKFTPPAESGSPSKETLPPP------AAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053 TPP + G+P+ PP A PP G N + V P +G + P Sbjct: 1254 --GPATPPPK-GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS--PKGGPATSPP-- 1306 Query: 1054 SGRGKDSVVEFPSPPSDSDFPPP-----PPETELPLP------PIEIPAVFSGNTSPKVA 1102 G PSP PPP PP P P P P+ G T+P Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366 Query: 1103 VVNPQPQQWSKMSVKKAPPPTRPKR--------NDSTRLTQAEISEQPTMATVVPQVPTS 1154 P A P PKR D T +S + AT V + + Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426 Query: 1155 PKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQ 1214 S + P + ++ + G ++ S+ +PT PP P E + +Q Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL---PAVTPPSPKEPPAPKQ 1483 Query: 1215 KAGYGGSHISGYATLRRGPP------PAPPKRDQNTKLSR 1248 A + G P P+ PK T SR Sbjct: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523 Score = 160 bits (406), Expect = 5e-39 Identities = 186/701 (26%), Positives = 242/701 (34%), Gaps = 109/701 (15%) Query: 601 PYTSLVPPLSPQPKIVTP-----YTASQPSPPLP--PPPPPPPPPP-------------- 639 P +L P+SP P + S+ SP P PP P P Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879 Query: 640 -PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698 PP P P + + P G A P + ++ ++ + + A P P S Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS---- 935 Query: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758 P G PP PP P G A K AP P +A PP K + Sbjct: 936 ------PKGAPTPPAATPPSPKGGPATPSPKWAPTPP-----AATPPSPKGGPATPSPKG 984 Query: 759 APPTPPPPPPIP-----APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPP 812 AP P PP P P P AP P VT P+P + P A+ PP TPP P Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP- 1043 Query: 813 AKKQPAFPASYIPPSPPTPPVPVPP-----PTLPKQQSFCAKPPPSPLSPV--PSVVKQI 865 K PA A+ +P PT P P P P + P +P SP P+ Sbjct: 1044 -KGSPA--ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100 Query: 866 ASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW-----QPSSIPVPSPDFPPPP 920 + PP TPP+ + P P AP +P A PK P P +P PP Sbjct: 1101 GAPMPPAATPPSPKGGLATP-PHKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAATPPS 1158 Query: 921 PESSLVFPPPPPSP-VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979 P+ L PPP +P PA PP P TP G+P + SP G P+P+ Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK--- 1215 Query: 980 SIKSSSGAEHPEPK------RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033 ++ A P PK P TPP+ G P+ T PP AP P Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA--TPPPKGAPTPPAA---- 1269 Query: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF 1093 P L+ G + P G +VV +PPS P P P PP P Sbjct: 1270 ---TPPSLKGGLAT---PPHKGAPNPAVV---TPPSPKGGPATSPPKGAPTPPAATPPSP 1320 Query: 1094 SGNTSPKVAVVNPQPQQWSKMSVKKAP--PPTRPKRNDSTRLTQAEISEQPTMATVVP-- 1149 G+ P P + S K P P T P T E PT P Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP--TTPSSKEGPTPPAATPSH 1378 Query: 1150 -----QVPTSPKSSLSV--------QPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTAT 1196 P SPK ++ P + + +TR G+ + P A Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA- 1437 Query: 1197 MDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAP 1237 + ++L P + K G G TL PP+P Sbjct: 1438 VTPVSLKKAP---ATSAPKGGPATPSSKGDPTLPAVTPPSP 1475 Score = 150 bits (378), Expect = 1e-35 Identities = 165/652 (25%), Positives = 227/652 (34%), Gaps = 114/652 (17%) Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPS--AG 658 P T P SP+ + TP P+ P PP P P PPP P P+ + PS G Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277 Query: 659 SAAPMFVKYSTITRLQNASQHSGALFKPP----TPPVMQSQSVKPQILVPPNGVVPPPPP 714 A P + S G PP TPP S K PP P PP Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337 Query: 715 PPPP-----PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769 PP PT + K P PS + PP H+ + PP+P P I Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG--PAMTPPSPKRGPAI 1395 Query: 770 PAPL------------PPQAPPKPLVTIPAPTSTK------TVAPVVTQAAPPTPTPP-- 809 P+P P +AP P+ A T +K V PV + AP T P Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455 Query: 810 --VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867 P +K P PA +PP+P P PKQ + + P +P +P P + + Sbjct: 1456 PATPSSKGDPTLPAV----TPPSPK----EPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507 Query: 868 QFPPP----PTPPAMESQPLKP--------VPANVAPQS---PPAVKAKPKWQPSSIPVP 912 P P P+ P+ P PA +AP+ PPA+ + +IP P Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567 Query: 913 --SPDFP-------PP----------PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS 953 +P P PP P L+ PP SP P P PP P+P+K Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627 Query: 954 -GSPGKKTSKTS---SPGGKKPPPTPQRNSSIKSSSGAEHPE-----PKRPSVDSLVSKF 1004 +P K + TS +P K PT +S+ GA P+ P + +L Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSP--ASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685 Query: 1005 TPPAESGSP------------SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPV 1052 PA +P K + P P P N S G L + PV Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS----KGPLSTVAPAPLLPV 1741 Query: 1053 LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112 K + + S PP + PL V P+ A V+ P Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL---PKPESASVSAAPSPPV 1798 Query: 1113 KMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMA-------TVVPQVPTSPKS 1157 + + +P PT P + + + E P+ ++P +P P S Sbjct: 1799 SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850 Score = 117 bits (293), Expect = 7e-26 Identities = 160/657 (24%), Positives = 228/657 (34%), Gaps = 99/657 (15%) Query: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703 P P +SA AG A ST T + P PV + ++ Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702 Query: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA---PSLPQFSAPPPPLKIHQVQHITQVAP 760 + P P P P + + P + PSLP PP K+ + H + +AP Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762 Query: 761 PTPPPP--PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818 P P + A K +T A + + P+ +P T PP KK A Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPS----PLGVSVSPQTKRPPT---KKGSA 815 Query: 819 FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878 P TP + P P + SF P + LS S + P PP+P Sbjct: 816 --------GPDTPIGNLSSPVSPVEASFL---PENSLSFQGSKDSPATTHSPTPPSPKGA 864 Query: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPS----SIPVPSPDFPPPPPESSLVF------- 927 P P+ V P SP V PK P+ ++P P P P+ + Sbjct: 865 ------PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918 Query: 928 ----PPPPPSPVPAPPPP---PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980 P P +PA P P P P A+ P G P + K + PP+P+ + Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978 Query: 981 IKSSSGAEHPE----------PKRPSVDSLVS--KFTPPAESGSPSKETLP-----PPAA 1023 S GA P P PS + TPP+ GSP+ P PPAA Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038 Query: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVL----SGRGKDSVVEFP-----SPPSDSDFP 1074 P K + + LP +G + A L G S+ P +PPS P Sbjct: 1039 TPPSPKGSPAATPLP----KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094 Query: 1075 PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPP------PTRPKRN 1128 P P+PP P SPK + P P + + + PP T P + Sbjct: 1095 ATPSPKGAPMPPAATP------PSPKGGLATP-PHKGAPTTPAATPPSPKGGLATPPPKG 1147 Query: 1129 DSTRLTQAEISEQPTMATVVPQ-VPTSPKSSLSVQPGFLADLN-----RTLQRKSITRHG 1182 T S + +AT P+ PT+P ++ G LA + T + G Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207 Query: 1183 SLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPK 1239 L++ + PT A PP P L+ G + + + + GP PPK Sbjct: 1208 GLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261 Score = 108 bits (271), Expect = 2e-23 Identities = 131/490 (26%), Positives = 177/490 (36%), Gaps = 94/490 (19%) Query: 585 TQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPP-- 642 T + A S P V P SP+ A+ SP P P P P P Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508 Query: 643 -PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQI 701 P P +P+ + AP + L TP + + + Sbjct: 1509 IPSSPKEVPATPSSRRDPIAP-----------------TATLLSKKTPATLAPK----EA 1547 Query: 702 LVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP 761 L+PP VP P P PTP K AP PS + S+PP V T P Sbjct: 1548 LIPPAMTVPSPKKTPAIPTP-------KEAPATPSSKEASSPP------AVTPSTYKGAP 1594 Query: 762 TPPP---PPPIPAPLPPQAPPKPLVT---------IPAPTSTKTVAPVVTQAAPPTPTPP 809 +P PP + +P P +AP P VT PAP T T PV + +PT P Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654 Query: 810 ----------VP------PAKKQP-AFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852 VP PAKK P A + P+P + P+ + PT Q+ + Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI-ITAPTRKGPQTKKSSATS 1713 Query: 853 SPLSPVPSV---VKQIASQFPPPPTPPAME--SQPLKPVPANVAPQSPPAVKAKPKWQPS 907 P+ P PS K S P P P + S+ K A+ +P+ P A P + Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA----PPESKA 1769 Query: 908 SIPVPSPDFP---PPPPESSLVFPPPPPSPVP-APPPPP--PPTASPTPDKSGSPGKKTS 961 S P+ + F P P +S+ P PP +P AP P P PP P G + S Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS 1829 Query: 962 KTSSPGGKKP-----PPTPQRNSSIKSSSGAEHPEPK-------RPSVDSLVSKFTPPAE 1009 K +P + PP P S P PK PS V+K + Sbjct: 1830 KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSG 1889 Query: 1010 SGSPSKETLP 1019 + S S E++P Sbjct: 1890 TESDSDESVP 1899 Score = 107 bits (268), Expect = 5e-23 Identities = 123/472 (26%), Positives = 171/472 (36%), Gaps = 106/472 (22%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPP------------PPPPPPLPSQSAP 655 P + PK +S+ P LP PP P PP P P P P+ + + P Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506 Query: 656 SAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715 + ++P V + +R ++ + L TP + + + L+PP VP P Sbjct: 1507 AVIPSSPKEVPATPSSR-RDPIAPTATLLSKKTPATLAPK----EALIPPAMTVPSPKKT 1561 Query: 716 PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP---PPPIPAP 772 P PTP K AP PS + S+PP V T P+P PP + +P Sbjct: 1562 PAIPTP-------KEAPATPSSKEASSPPA------VTPSTYKGAPSPKELLIPPAVTSP 1608 Query: 773 LPPQAPPKPLVT---------IPAPTSTKTVAPVVTQAAPPTPTPP----------VP-- 811 P +AP P VT PAP T T PV + +PT P VP Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668 Query: 812 ----PAKKQP-AFPASYIPPSPPTPPVPVPPPTLPKQ--QSFCAKPP------------- 851 PAKK P A + P+P + P+ P Q +S PP Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728 Query: 852 ------PSPLSPVPSVVKQIA-----SQFPPPPTPP--AMESQPLK--------PVPANV 890 P+PL PV + A S P P P + S PL P P + Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788 Query: 891 APQSPPAVKAKPKWQPSSIPV--PSPDFPPPPPESSLVFPPPPPSPVP----APPPPPPP 944 + + P+ PS +P P F P P L P P +P P PP P Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848 Query: 945 TASPTPDKSGSPGKKTSKTS-----SPGGKKPPPTPQRNSSIKSSSGAEHPE 991 + P +S T K++ +P K+P + S +S S PE Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPE 1900 Score = 63.9 bits (154), Expect = 9e-10 Identities = 133/591 (22%), Positives = 206/591 (34%), Gaps = 92/591 (15%) Query: 623 QPSPPLPPP-PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG 681 QP P LPPP P P P P PS PS ++ P+ V + Q++S + Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPFPS---PSTIASTPLEVPFP-----QSSSGTAL 91 Query: 682 ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS----AMAQLKPAPCAPSL 737 L P P + P I + P P TP S A+ L P S Sbjct: 92 PLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSS 151 Query: 738 ---PQFSAPPPPLKIHQVQHITQVAPPTPPPPPP----------IPAPLPPQAPPKPLVT 784 P PP + + + + ++ P P P +P P +PP + T Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211 Query: 785 IP-----APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP---TPPVPVP 836 +P S ++ + Q P T P K + I P P + PV Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271 Query: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV------PANV 890 PP A + PV + ++ A PP P ++ S L P+ + Sbjct: 272 PP--------AALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSH-LAPLHQSSFGSVQL 322 Query: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950 Q+ P+ + P + S+ S P + S++ P P + V P +P+ Sbjct: 323 LGQTGPSALSDPTVKTISVDHSSTG-ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV 381 Query: 951 DKSGSPGKKTSKTSSPGGKKPPPT-----PQRNSSIKSSSGAEHPEP---KRP--SVDSL 1000 DK P +S T SP G T P + +KSS A + P + P SV + Sbjct: 382 DK--GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTT 439 Query: 1001 VSKFTPP---AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 T P A + + + E + P G ++ P L V+ K P Sbjct: 440 PLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEP---STQ 496 Query: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPP---IEIPAVFSGNTSPKVAVVNPQPQQWSKM 1114 + + P P P P PE LP ++ P T P P + + Sbjct: 497 VATTLRIPVSP-----PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGL 551 Query: 1115 SVKKAPP-----PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLS 1160 + KK P PK + S + T + P++P SP+++L+ Sbjct: 552 TTKKDPTVLPLVQAAPKNSPSFQSTSSS-----------PEIPLSPEATLA 591 Score = 59.3 bits (142), Expect = 2e-08 Identities = 117/512 (22%), Positives = 168/512 (32%), Gaps = 75/512 (14%) Query: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796 LPQ A L + +T P PP +P P Q P S T+A Sbjct: 16 LPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAS 75 Query: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCA-------K 849 + P P + A P P +P P + PP P + + K Sbjct: 76 TPLEV-------PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128 Query: 850 PPPSPLSPVPSVV-----KQIASQFPP-----PPTPPAMESQPLKPVPANVAPQSPPAVK 899 PS +P+ V Q +S FPP PP+ ES + + A +AP P K Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP---K 185 Query: 900 AKPKWQPSSIPVPSPDFPPPPPESSLVFP---PPPPSPVPAPPPPPPPTASPTPDKSGSP 956 PS + VP+P P PP P P + + + P T T SP Sbjct: 186 TNLNKVPSEV-VPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244 Query: 957 GKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE 1016 K + SS +PQ S+ S G P P+ SL ++ P S + Sbjct: 245 QVKDTTISS-----VLISPQNPGSL-SLKGPVSP----PAALSLSTQSLPVVTSSQKTAG 294 Query: 1017 TLPPPAAPPKPG-------KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPS 1069 PP P G + + V L G Q G + P + D S PS Sbjct: 295 PNTPPDFPISLGSHLAPLHQSSFGSVQLLG--QTGPSALSDPTVKTISVDHSSTGASYPS 352 Query: 1070 DSDFPPPPPETELPLP------PIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPT 1123 PP P +P P+ P+V G ++ ++ + P ++ + PT Sbjct: 353 QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPST--ISSITCSPSGSLNVATSFSLSPT 410 Query: 1124 RPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP-------GFLADLNRTLQRK 1176 T + P P V P SS+ P A T + Sbjct: 411 ----------TSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVA 460 Query: 1177 SITRHGSLSSRMSRAEPTATMDDMALPPPPPE 1208 + S +S EPT+ + P P E Sbjct: 461 TCVSPPMSSGPISNIEPTSPAALVMAPVAPKE 492 Score = 58.9 bits (141), Expect = 3e-08 Identities = 107/465 (23%), Positives = 163/465 (35%), Gaps = 87/465 (18%) Query: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828 +PA P+ + +S +V + Q P P P P ++ P A+ P P Sbjct: 9 VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP 68 Query: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA------MESQP 882 + P +P QS + PL P + + PP +P A M + Sbjct: 69 SPSTIASTPLEVPFPQS--SSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126 Query: 883 LKPVPANVAP-----QSPPAVKAKPKWQPSSIPVP--------------SPDFPPPPPES 923 LK P++ AP +P +V+ + P+ + P S P P++ Sbjct: 127 LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186 Query: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983 +L P P P P PP S P +P + S P TP +I S Sbjct: 187 NLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTP---MASIQSGVASLPQTTPTTTLAIAS 243 Query: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG-VNLPGVLQ 1042 P+ K ++ S++ +P PG L+L G V+ P L Sbjct: 244 ------PQVKDTTISSVL--------------------ISPQNPGSLSLKGPVSPPAALS 277 Query: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAV-FSGNTSP-- 1099 S PV++ K + P + DFP PL +V G T P Sbjct: 278 LSTQS--LPVVTSSQKTA-----GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSA 330 Query: 1100 ------KVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPT 1153 K V+ S S + PP P RN+ + A ++ P +A V + P+ Sbjct: 331 LSDPTVKTISVDHSSTGASYPSQRSVIPPL-PSRNE---VVPATVAAFPVVAPSVDKGPS 386 Query: 1154 -------SPKSSLSVQPGFLADLNRTLQRKS---ITRHGSLSSRM 1188 SP SL+V F +L KS T H L ++M Sbjct: 387 TISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQM 431 Score = 52.4 bits (124), Expect = 3e-06 Identities = 138/614 (22%), Positives = 186/614 (30%), Gaps = 150/614 (24%) Query: 682 ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA----PCAPSL 737 A F P V + S I P+G + PT + A P + Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQM 431 Query: 738 PQFSAPPPPLKIHQVQHITQVAPPTPP-------PPPPIPAPLPPQAPPKPLVTIPAPT- 789 P S PL + T A PT PP P+ P P + AP Sbjct: 432 PVSSVGTTPLVV--TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489 Query: 790 ----STKTVAPVVTQAAPPTPTP------------PVPPAKKQPAFPASY--IPPSP--- 828 ST+ + +PP P P P K PAS P SP Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549 Query: 829 -------PT--PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-IASQFP-------- 870 PT P V P P QS + P PLSP ++ K+ + P Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQS-TSSSPEIPLSPEATLAKKSLGEPLPIGKPASSM 608 Query: 871 --------------------PPPTPPAMESQPLKPV----------PANVAP-------- 892 P P ++S + P PA VAP Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668 Query: 893 ---QSPPAVKAKPKWQPSSIPVPSPDFP-----PPPPESSLVFPPPPPSPVP------AP 938 + P ++ P + PV P E+ V P P + P AP Sbjct: 669 YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728 Query: 939 ------PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG------ 986 P P P A P G + +P P P +S +++ Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLT 788 Query: 987 --AEHPEPKRPSVDSLVSKFTPPAESGSPSKET----LPPPAAPPKPGKLNLSGVNLPGV 1040 A+ P P SV + PP + GS +T L P +P + L + ++ G Sbjct: 789 YLADSPSPLGVSVSPQTKR--PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846 Query: 1041 LQQGCV--SAKAPVLSGRGKDSVVEFPSPPSDSDFP----PPPPETELPLP--------P 1086 S P G S V P P P P P LP P P Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVT-PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905 Query: 1087 IEIPAVFSGNTSPKVAVVNPQPQQW-SKMSVKKAPPP---TRPKRNDSTRLTQAEISEQP 1142 + PA+ ++SPK A P P+ + S K AP P T P + + P Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965 Query: 1143 TMATVVPQVPTSPK 1156 AT P SPK Sbjct: 966 PAAT-----PPSPK 974 Score = 47.0 bits (110), Expect = 1e-04 Identities = 69/304 (22%), Positives = 105/304 (34%), Gaps = 27/304 (8%) Query: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP-----PAMES 880 P T VP LP+ Q+ A P S V + + Q PPP +P P + Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61 Query: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP-ESSLVFPPPPPSPVPAPP 939 P P+ S P P+ S +P P P +L+ PP P+ + Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQ-SSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120 Query: 940 PPPPPTASPTPDKSG-------SPGKKTSKTSSPGG---KKPPPTPQRNSSIKSSSGAEH 989 P PT TP S +P ++ P P + S+ + S Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180 Query: 990 PEPKRPSVDSLVSKFTPPAESGSPSK----ETLPPPAAPPKPGKLNLSGVNLPGVLQQGC 1045 P + +++ + S+ P + G+PS T+P P + +LP Sbjct: 181 PSEPKTNLNKVPSEVVPNPK-GTPSPPCIVSTVPYHCVTPM-ASIQSGVASLPQTTPTTT 238 Query: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFP-PPPPETELPLPPIEIPAVFSGNTSPKVAVV 1104 ++ +P + SV+ P P P P L L +P V S S K A Sbjct: 239 LAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS---SQKTAGP 295 Query: 1105 NPQP 1108 N P Sbjct: 296 NTPP 299 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 169 bits (428), Expect = 2e-41 Identities = 199/759 (26%), Positives = 270/759 (35%), Gaps = 160/759 (21%) Query: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFS--EAWKRGTQLE 588 SS +SG S+ P + ++ S G+ +P + + + T Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309 Query: 589 ESSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647 +KAR + + T L L P P + TP + PSP PP P PP PP P Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369 Query: 648 PL----PSQSAPSAGSAAPMFVKYS-TITRLQ--------NASQHSGALFKPPTPPVMQS 694 P P Q+ PS + P+ V +S T LQ ++ Q + +L P Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429 Query: 695 QSVKPQ----ILVPPNGVVPPPPPPPP----------PPTPGSAMAQLKP---------- 730 ++ P+ L P+ PP PP PP S + P Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489 Query: 731 ---------APCAP---------------SLPQFSAPPPPLKIHQVQHITQVAPP----- 761 +P AP + P PP L ++++ +APP Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549 Query: 762 ----TPP--PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 T P PP PAP P QAPP PL T P P + ++A QA P +PP+ Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTT-PPPETPSSIATPPPQAPPALASPPLQGLPS 608 Query: 816 QPAFPASYIPPSPPTPPVPVP----PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP 871 P P + PP P P + +P PP+ P PSP +P V + + F P Sbjct: 609 PPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667 Query: 872 PPTPPAM------ESQPLKP--VPANVAP--------QSPPAVKAKPKWQPSSIPVPSPD 915 PP+PP S P+ P P + AP Q PP+ A P PS+ P P Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--TPPPQ 725 Query: 916 FPPPPPESSLVFPPPPPSPVP----APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971 PPP L PP PP+ P A PPP P P P S SP K P Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785 Query: 972 P--------------PTPQRN---------SSIKSSSGAEHPEPKRPSVDSLVSKFTPPA 1008 P P+P + S+ S P P+ P V + PP+ Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845 Query: 1009 ESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQQG---------CVSAKAPVLSGRGK 1058 SP TL P PP PG ++SG L L G + P L+G Sbjct: 846 PPASP---TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902 Query: 1059 ------DSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV--VNPQPQQ 1110 + + + S P PPP+ EL PA +S +P +A P Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACH---PAAWSRGPAPPLAFRGAPGAPLP 959 Query: 1111 WSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP 1149 W PP T P D L +E P AT P Sbjct: 960 W--------PPATGPGSADG--LCTIYETEGPESATPAP 988 Score = 164 bits (416), Expect = 4e-40 Identities = 172/564 (30%), Positives = 219/564 (38%), Gaps = 118/564 (20%) Query: 587 LEESSKARMESMNRPYTSLV-PPLSPQPKIVTP--YTASQP--SPPLPPPPPPPP----P 637 LE S S+ P SL PPL P + P TAS P +P L PP P P Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571 Query: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697 PP P PPP PS A A P S L P+PP+ + Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALA--------------SPPLQGLPSPPLSPLATP 617 Query: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757 PQ PP +PP PP PP P+P AP+ L +H +Q Sbjct: 618 PPQ--APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA---------LAVHLLQ---- 662 Query: 758 VAPPTPPPPPPIPAPL-PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816 AP +PPP PP+ AP PP +PP +P++T + AAPP PP PPA Sbjct: 663 -APFSPPPSPPVQAPFSPPASPPV------SPSATPPSQAPPSLAAPPLQVPPSPPASP- 714 Query: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876 P P++ PP P PP+ PP +P A PP SP S PPP PP Sbjct: 715 PMSPSATPPPQAP-PPLAAPPLQVPPSPP--ASPPMSP------------SATPPPRVPP 759 Query: 877 AMESQPLKPVP-----------ANVAPQSPPAVKAKP----KWQPSSIPVPSPDFPPPP- 920 + + PL+ P A PQ+PPA+ P P+S P +P P Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819 Query: 921 PESSLVFPPPPPSPVPAPP---PPPPPTASPT---PDKSGSPGKKTSKTSSP-------G 967 P S L PPP PV A P PP P ASPT P + +PG TS S P Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS-VSGPRLTLALAP 878 Query: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027 G PPP+ +S++ A H + + L + P + S PPP A Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS----PPPDA---- 930 Query: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD---------FPPPPP 1078 L+ + P +G AP L+ RG P PP+ + P Sbjct: 931 ---ELAACH-PAAWSRG----PAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGP 981 Query: 1079 ETELPLPPIEIPAVFSGNTSPKVA 1102 E+ P P P G + K A Sbjct: 982 ESATPAPGALDPGPSPGTSGGKAA 1005 Score = 150 bits (379), Expect = 7e-36 Identities = 208/816 (25%), Positives = 281/816 (34%), Gaps = 192/816 (23%) Query: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594 SG + P ++ S G S T G + + + S E RG E ++ Sbjct: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 155 Query: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---------- 644 + + R TS P +P P + A+ LP P P P PP P Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215 Query: 645 ----PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG--------ALFKPPTPPVM 692 P P + + G P S+ ++ SG A P P Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275 Query: 693 QSQSVKPQILVPPNGVVPP---PPPPPPPPTPGSAMAQLKPAP----CAPSLPQFSAPPP 745 Q+++P + PP P P P TP + + +P P A LP P P Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335 Query: 746 PLKIHQVQHITQVAPPTPPPPPPIPA-PLPPQAPPK---PLVTIP---APTSTKTVAPVV 798 PL +APP+P PP + P PP PP P +T P AP S +T+ P+ Sbjct: 336 PLATP-----LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390 Query: 799 TQAAPPTPTPPVPPAK-----------------------------------KQPAFPASY 823 + +P+ PP+ P+ PAS Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450 Query: 824 IPPSPP-TPPVPVP-PPTLPKQQSFCAKPPPSPLSPVP-SVVKQIASQFPPPP-----TP 875 P SPP P+ +P P L S P SPL+ P + +AS P P P Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510 Query: 876 PAMESQPLKPVPANVAPQS---PPAVK----AKPKWQPSSIPVPSPDFPPPP-------- 920 P L P P S PP A P Q +S P+ +P PP Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570 Query: 921 -PESSLVFPPP-PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP------- 971 P S L PPP PS + PPP PP A +P G P S ++P + P Sbjct: 571 APPSPLTTPPPETPSSIATPPPQAPP-ALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629 Query: 972 ---PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028 PP+P + + + P +V L + F+PP P + PPA+PP Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASPP--- 684 Query: 1029 KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP---PPPETELPL- 1084 +S P Q S AP L PSPP+ P PPP+ PL Sbjct: 685 ---VSPSATPP--SQAPPSLAAPPLQVP--------PSPPASPPMSPSATPPPQAPPPLA 731 Query: 1085 -PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPT 1143 PP+++P P P MS PPP P P Sbjct: 732 APPLQVP---------------PSPPASPPMSPSATPPPRVP----------------PL 760 Query: 1144 MATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPT-ATMDDMAL 1202 +A QVP SP +SL + P L+ +A P AT AL Sbjct: 761 LAAPPLQVPPSPPASLPMSP--------------------LAKPPPQAPPALATPPLQAL 800 Query: 1203 PPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPP 1238 P PP S +A + S + L PP APP Sbjct: 801 PSPP---ASFPGQAPFSPSASLPMSPLATPPPQAPP 833 Score = 123 bits (309), Expect = 1e-27 Identities = 155/628 (24%), Positives = 235/628 (37%), Gaps = 79/628 (12%) Query: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPV 691 P PP P PPPP P L A A P+ + A GA P Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL---------AERAGGIGGATIPESAPRA 77 Query: 692 MQSQSV-----KPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKPAPCAPSLPQFS 741 ++S P P +G PP P P +PG A +P P + S Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137 Query: 742 APP----------PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS- 790 A P + PTP P P A A + + PAP++ Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197 Query: 791 ----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846 T+ V+ A+ + T P P A+++P+ P+ + P + P + Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257 Query: 847 CAKPPP-SPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPAN-VAPQSPPAVKAKPK 903 A+ P +P P K + + PP TPP ++ P L P+ ++ +A SP KA+P Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317 Query: 904 WQPSSIPVPSPDFPPPPPESSLVFPPPPPSP--------VPAPPPPPPPTASP---TPDK 952 P + P P PP P + P PPSP +P+PP PP A P TP Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377 Query: 953 SGSPGKKT-------SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005 P +T +SP + PP+P SS+++++ P + +S Sbjct: 378 QAPPSLQTIPPIQVPHSLTSP-SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436 Query: 1006 PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP 1065 A SPS+ PP +PP L+L LQ A +P+ S + Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPA---SPPLQTSLSPAVSPLSSPLTIHPLQALS 493 Query: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFSGNT--SPKVAVVNPQPQQWSKMSVKKAPPPT 1123 S S S P P + L +PP+E + + + +P ++ P + + APPP Sbjct: 494 SLASHS---PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL----APPPL 546 Query: 1124 RPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGS 1183 + S LT + P A Q P SP L+ P + ++ + Sbjct: 547 ---QTASAPLTTPHLETPPCPAPCPLQAPPSP---LTTPP---PETPSSIATPPPQAPPA 597 Query: 1184 LSSRMSRAEPTATMDDMALPPP--PPEL 1209 L+S + P+ + +A PPP PP L Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXL 625 Score = 71.2 bits (173), Expect = 6e-12 Identities = 111/462 (24%), Positives = 154/462 (33%), Gaps = 105/462 (22%) Query: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM----------------------- 878 K ++ A P+ +P + S PPPP PA Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 879 -----ESQP----------LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP------DFP 917 ES P PA+ P S +A P S PV SP P Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 918 PP----------------------PPESSL-------VFPPPPPSPVPAPP--------- 939 P P S+L P P +P PA Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186 Query: 940 ---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS 996 P P P+A P P G P K S S +P P +R + S+G P S Sbjct: 187 VGLPRPAPSARPRPPTEG-PRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRS 241 Query: 997 VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGR 1056 + S + + PA SG ++ T PA P +P L + P V AP L G Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR--KDAAPAL-GP 298 Query: 1057 GKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116 S + PSP P PPP+ P +P S + + + P P + Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP--SPPLATPLPLAPPSPSAPPSLQT 356 Query: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP-QVP---TSPKSSLSVQPGFLADLNRT 1172 +PP T P + + +T + P++ T+ P QVP TSP P L+ L T Sbjct: 357 LPSPPATPPSQAPPS-MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415 Query: 1173 LQRKSITRHG-----SLSSRMSRAEPTATMDDMALPPPPPEL 1209 S T ++S R ++A T+ + PP P L Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL 457 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 168 bits (426), Expect = 3e-41 Identities = 182/713 (25%), Positives = 266/713 (37%), Gaps = 106/713 (14%) Query: 518 KRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVF 577 ++T SA + S+ +S K + +S + + + + G + T P + Sbjct: 168 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-------- 219 Query: 578 SEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP 637 T E +S E P T P +P+ T ++ +P P P P Sbjct: 220 -------TPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270 Query: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697 P P P P + AP+ +AP K P TP + Sbjct: 271 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----------------PTTPKKPAPTTP 314 Query: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK-PAPCAPSLPQFSAPPPPLKIHQVQHIT 756 K P P P P P T A K PAP AP P + P P Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP---------- 364 Query: 757 QVAPPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812 AP TP P P P+P P+ P P T APT+TK AP T++AP TP P P Sbjct: 365 --APTTPKEPAPTTTKEPSPTTPK-EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421 Query: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP-- 870 K+PA P + P+P TP P PT PK+ + P +P P P+ K+ A P Sbjct: 422 TTKEPA-PTTPKEPAPTTPKKPA--PTTPKEPA-----PTTPKEPAPTTTKKPAPTTPKE 473 Query: 871 PPPTPPAMESQPLKP------VPANVAPQSP--PAVKAKPKWQPSSIPVPSPDFP--PPP 920 P PT P E+ P P P +AP +P PA + P++ P+P P P P Sbjct: 474 PAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532 Query: 921 PESSLVFPPPPPSPVPAPPPPPPPTA--SPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQR 977 P P P P P P PT P P T K ++P K+P PT + Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592 Query: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV-- 1035 + K + EP + D + TP + + KE P P P +P G Sbjct: 593 KPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAP 649 Query: 1036 -----NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090 P ++ AP + + + P+P + + P P+ P P + P Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-KKP 708 Query: 1091 AVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATV--- 1147 A + T P P + S + K P ++ST E+S +PT + Sbjct: 709 APTTPETPP------PTTSEVSTPTTTKEPTTIHKSPDEST----PELSAEPTPKALENS 758 Query: 1148 --VPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMD 1198 P VPT+ K+ + +P ++ T + K+ R + + A P T + Sbjct: 759 PKEPGVPTT-KTPAATKP----EMTTTAKDKTTERDLRTTPETTTAAPKMTKE 806 Score = 154 bits (388), Expect = 7e-37 Identities = 164/663 (24%), Positives = 242/663 (36%), Gaps = 83/663 (12%) Query: 614 KIVTPYTASQPSPPLPPPPP---PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670 K+ TP T++ + P P P P PP +++ + + K +T Sbjct: 98 KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 157 Query: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKP---QILVPPNGVVPPPPPPPPPPTPGSAMAQ 727 T Q ++ K T ++QS++ + L P + V+ P P T G A+ Sbjct: 158 TNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 212 Query: 728 LK-PAPCAPSLPQFSAP--PPPLKIHQVQHI--------TQVAPPTPPPPPPI----PAP 772 K P P P P + P P P I T+ AP TP P P PAP Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272 Query: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832 P+ P PAPT+TK+ + AP TP P P K+PA P + P+P TP Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPK 331 Query: 833 VPVPP-----PTLPKQQSFCA--KPPPS-PLSPVPSVVKQIA---SQFPPPPTPPAMESQ 881 P P PT PK+ + A KP P+ P P P+ K+ A ++ P P TP Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391 Query: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 K P +P K+ P P + + P P+ P P+P P Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKK--PPPTPQRNSSIKSSSGAEHPEPKRPSVDS 999 P P P + P T K +P K P TP++ + PE P+ Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT-------PEKLAPTTPE 504 Query: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKD 1059 + TP E +P+ P P P +P P AP Sbjct: 505 KPAPTTP--EELAPTTPEEPTPTTPEEPAP------TTPKAAAPNTPKEPAPTTPKEPAP 556 Query: 1060 SVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKK- 1118 + + P+P + + P P+ P ++ PA T+PK P P++ + + K+ Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAP-TTLKEPA----PTTPK----KPAPKELAPTTTKEP 607 Query: 1119 ------APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRT 1172 P PT PK T ++P T PT+PK + P L + T Sbjct: 608 TSTTCDKPAPTTPKG------TAPTTPKEPAPTTPKEPAPTTPKGT---APTTLKEPAPT 658 Query: 1173 LQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRG 1232 +K + + ++ PT+T D P P E K + T Sbjct: 659 TPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 715 Query: 1233 PPP 1235 PPP Sbjct: 716 PPP 718 Score = 147 bits (371), Expect = 6e-35 Identities = 159/649 (24%), Positives = 231/649 (35%), Gaps = 81/649 (12%) Query: 601 PYTSLVP-PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGS 659 P T+ P P + + TP + +P P P P P P P P P P + AP+ Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 339 Query: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPP 719 AP K T + + + P TP + K P P P Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399 Query: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI----PAPLPP 775 T A K AP P P + P AP TP P P PAP P Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEP------------APTTPKEPAPTTPKKPAPTTP 447 Query: 776 QAPPKPLVTIPAPTSTKTVAPVV-TQAAPPTP--TPPVPPAKKQPAFPASYIPPSPPTPP 832 + P PAPT+TK AP + AP TP T P P K P P + P+ P P Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKP 506 Query: 833 VPVPP----PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP-------PAMESQ 881 P P PT P++ + P +P P P+ K A P P P P + Sbjct: 507 APTTPEELAPTTPEEPT-----PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561 Query: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPPPPS-----P 934 P P AP +P P+++ P+P P P P E + P S P Sbjct: 562 PAPTTPKETAPTTPKGT------APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615 Query: 935 VPAPPPPPPPTA--SPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQRNSSIKSSSGAEHPE 991 P P PT P P P T K ++P K+P PT + + K + Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675 Query: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL-------NLSGVNLPGVLQQG 1044 P + D T P E+ +P+ P P P KP S V+ P ++ Sbjct: 676 PTSTTSDKPAP--TTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732 Query: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV- 1103 K+P +S E + P+ P E +P + PA T P++ Sbjct: 733 TTIHKSP------DESTPELSAEPTPKALENSPKEP--GVPTTKTPAA----TKPEMTTT 780 Query: 1104 ----VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSL 1159 + + + + AP T+ + + T+++I+ T T T+P Sbjct: 781 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 840 Query: 1160 SVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPE 1208 +++ LA T +K+IT ++ A+P + P P+ Sbjct: 841 TLKTTTLAP-KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 888 Score = 144 bits (363), Expect = 5e-34 Identities = 165/663 (24%), Positives = 236/663 (35%), Gaps = 108/663 (16%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP--PPPPLPSQSAPSAGSA-APMF 664 P PK TP T +P+P P P P P P P P P P + AP+ AP Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376 Query: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724 K + S K P P +S + P P P P PT Sbjct: 377 TK-----------EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425 Query: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-PQAPPKPLV 783 A P AP+ P+ AP P + AP TP P P P P P +P Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476 Query: 784 TIP---APTSTKTVAPVVTQA-APPTPTPPVP--PAKKQPAFPASYIP-----PSPPTPP 832 T P APT+ K + P + AP TP P P P + P P P P+P TP Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536 Query: 833 VPV------PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME----SQP 882 P PT PK+ + P +P P P+ K+ A P P ++ + P Sbjct: 537 AAAPNTPKEPAPTTPKEPA-----PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591 Query: 883 LKPVPANVAPQS----------PPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP 930 KP P +AP + PA P++ P+P P P P P Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651 Query: 931 PPSPVPAPPPPPPP-------TASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIK 982 P P P P P T PT S P T K ++P K+P PT + Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK---P 708 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 + + E P P V + + P SP + T P +A P P L S PGV Sbjct: 709 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKE-PGVPT 766 Query: 1043 QGCVSAKAPVLSGRGKDSVVE---FPSPPSDSDFPPPPPET----------ELPLPPIEI 1089 +A P ++ KD E +P + + P ET ++ ++ Sbjct: 767 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826 Query: 1090 PAVFSGNTSP------KVAVVNPQPQQWSK----MSVKKAPPPTRPKRNDSTRLTQAEIS 1139 + + +T+P K + P+ K + P T ++ +T + Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT--NSKATT 884 Query: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199 +P T P+ PTS K + + R + K+ ++S M PT+ + + Sbjct: 885 PKPQKPTKAPKKPTSTKKPKT--------MPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 936 Query: 1200 MAL 1202 L Sbjct: 937 AML 939 Score = 134 bits (337), Expect = 5e-31 Identities = 165/687 (24%), Positives = 236/687 (34%), Gaps = 96/687 (13%) Query: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL 649 ++K+ + P + PK +P T +P+P P P P P P P P P Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451 Query: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVV 709 P+ + AP K T + + P TP + K P + Sbjct: 452 PT----TPKEPAPTTTKKPAPTTPKEPA--------PTTPKETAPTTPKKLTPTTPEKLA 499 Query: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769 P P P P TP +A P P+ P+ AP P AP TP P P Sbjct: 500 PTTPEKPAPTTP-EELAPTTPEEPTPTTPEEPAPTTP---------KAAAPNTPKEPAPT 549 Query: 770 ----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825 PAP P+ P APT+ K AP T P PT P PA K+ A P + Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP--TTLKEPAPTTPKKPAPKELA-PTTTKE 606 Query: 826 PSPPT--PPVPVPP----PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879 P+ T P P P PT PK+ + P +P P P+ K A P P Sbjct: 607 PTSTTCDKPAPTTPKGTAPTTPKEPA-----PTTPKEPAPTTPKGTAPTTLKEPAP---- 657 Query: 880 SQPLKPVPANVAPQSP--PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937 + P KP P +AP + P K P++ +P P P P P P P Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPT 711 Query: 938 PPPPPPPTAS----PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993 P PPPT S PT K + K+ S+P PTP+ + G P K Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEPGV--PTTK 768 Query: 994 RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053 P+ + T A+ + ++ P K+ + ++A + Sbjct: 769 TPAATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826 Query: 1054 SGRGKDSVVEFP-SPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112 + F + + P T+ + EI PK N S Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATN------S 880 Query: 1113 KMSVKKAPPPTR-PKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNR 1171 K + K PT+ PK+ ST+ + + T P+ TS L+ + + Sbjct: 881 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 940 Query: 1172 TLQRKSITRHGSLSSRMSRAE--------------------PTATMDDMALPPPPPE--- 1208 T R + T + L ++E P T D LP P + Sbjct: 941 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGII 1000 Query: 1209 ---LLSDQQKAGYGGSHISGYATLRRG 1232 +LSD+ G + G TLR G Sbjct: 1001 INPMLSDETNI-CNGKPVDGLTTLRNG 1026 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 168 bits (426), Expect = 3e-41 Identities = 182/713 (25%), Positives = 266/713 (37%), Gaps = 106/713 (14%) Query: 518 KRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVF 577 ++T SA + S+ +S K + +S + + + + G + T P + Sbjct: 209 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-------- 260 Query: 578 SEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP 637 T E +S E P T P +P+ T ++ +P P P P Sbjct: 261 -------TPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311 Query: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697 P P P P + AP+ +AP K P TP + Sbjct: 312 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----------------PTTPKKPAPTTP 355 Query: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK-PAPCAPSLPQFSAPPPPLKIHQVQHIT 756 K P P P P P T A K PAP AP P + P P Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP---------- 405 Query: 757 QVAPPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812 AP TP P P P+P P+ P P T APT+TK AP T++AP TP P P Sbjct: 406 --APTTPKEPAPTTTKEPSPTTPK-EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462 Query: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP-- 870 K+PA P + P+P TP P PT PK+ + P +P P P+ K+ A P Sbjct: 463 TTKEPA-PTTPKEPAPTTPKKPA--PTTPKEPA-----PTTPKEPAPTTTKKPAPTTPKE 514 Query: 871 PPPTPPAMESQPLKP------VPANVAPQSP--PAVKAKPKWQPSSIPVPSPDFP--PPP 920 P PT P E+ P P P +AP +P PA + P++ P+P P P P Sbjct: 515 PAPTTP-KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573 Query: 921 PESSLVFPPPPPSPVPAPPPPPPPTA--SPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQR 977 P P P P P P PT P P T K ++P K+P PT + Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633 Query: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV-- 1035 + K + EP + D + TP + + KE P P P +P G Sbjct: 634 KPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAP 690 Query: 1036 -----NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090 P ++ AP + + + P+P + + P P+ P P + P Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP-KKP 749 Query: 1091 AVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATV--- 1147 A + T P P + S + K P ++ST E+S +PT + Sbjct: 750 APTTPETPP------PTTSEVSTPTTTKEPTTIHKSPDEST----PELSAEPTPKALENS 799 Query: 1148 --VPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMD 1198 P VPT+ K+ + +P ++ T + K+ R + + A P T + Sbjct: 800 PKEPGVPTT-KTPAATKP----EMTTTAKDKTTERDLRTTPETTTAAPKMTKE 847 Score = 154 bits (388), Expect = 7e-37 Identities = 164/663 (24%), Positives = 242/663 (36%), Gaps = 83/663 (12%) Query: 614 KIVTPYTASQPSPPLPPPPP---PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670 K+ TP T++ + P P P P PP +++ + + K +T Sbjct: 139 KVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 198 Query: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKP---QILVPPNGVVPPPPPPPPPPTPGSAMAQ 727 T Q ++ K T ++QS++ + L P + V+ P P T G A+ Sbjct: 199 TNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 253 Query: 728 LK-PAPCAPSLPQFSAP--PPPLKIHQVQHI--------TQVAPPTPPPPPPI----PAP 772 K P P P P + P P P I T+ AP TP P P PAP Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313 Query: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP 832 P+ P PAPT+TK+ + AP TP P P K+PA P + P+P TP Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPTPTTPK 372 Query: 833 VPVPP-----PTLPKQQSFCA--KPPPS-PLSPVPSVVKQIA---SQFPPPPTPPAMESQ 881 P P PT PK+ + A KP P+ P P P+ K+ A ++ P P TP Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432 Query: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 K P +P K+ P P + + P P+ P P+P P Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKK--PPPTPQRNSSIKSSSGAEHPEPKRPSVDS 999 P P P + P T K +P K P TP++ + PE P+ Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT-------PEKLAPTTPE 545 Query: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKD 1059 + TP E +P+ P P P +P P AP Sbjct: 546 KPAPTTP--EELAPTTPEEPTPTTPEEPAP------TTPKAAAPNTPKEPAPTTPKEPAP 597 Query: 1060 SVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKK- 1118 + + P+P + + P P+ P ++ PA T+PK P P++ + + K+ Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAP-TTLKEPA----PTTPK----KPAPKELAPTTTKEP 648 Query: 1119 ------APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRT 1172 P PT PK T ++P T PT+PK + P L + T Sbjct: 649 TSTTCDKPAPTTPKG------TAPTTPKEPAPTTPKEPAPTTPKGT---APTTLKEPAPT 699 Query: 1173 LQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRG 1232 +K + + ++ PT+T D P P E K + T Sbjct: 700 TPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 756 Query: 1233 PPP 1235 PPP Sbjct: 757 PPP 759 Score = 147 bits (371), Expect = 6e-35 Identities = 159/649 (24%), Positives = 231/649 (35%), Gaps = 81/649 (12%) Query: 601 PYTSLVP-PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGS 659 P T+ P P + + TP + +P P P P P P P P P P + AP+ Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 380 Query: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPP 719 AP K T + + + P TP + K P P P Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440 Query: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI----PAPLPP 775 T A K AP P P + P AP TP P P PAP P Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEP------------APTTPKEPAPTTPKKPAPTTP 488 Query: 776 QAPPKPLVTIPAPTSTKTVAPVV-TQAAPPTP--TPPVPPAKKQPAFPASYIPPSPPTPP 832 + P PAPT+TK AP + AP TP T P P K P P + P+ P P Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKP 547 Query: 833 VPVPP----PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP-------PAMESQ 881 P P PT P++ + P +P P P+ K A P P P P + Sbjct: 548 APTTPEELAPTTPEEPT-----PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602 Query: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPPPPS-----P 934 P P AP +P P+++ P+P P P P E + P S P Sbjct: 603 PAPTTPKETAPTTPKGT------APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656 Query: 935 VPAPPPPPPPTA--SPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQRNSSIKSSSGAEHPE 991 P P PT P P P T K ++P K+P PT + + K + Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716 Query: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL-------NLSGVNLPGVLQQG 1044 P + D T P E+ +P+ P P P KP S V+ P ++ Sbjct: 717 PTSTTSDKPAP--TTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773 Query: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV- 1103 K+P +S E + P+ P E +P + PA T P++ Sbjct: 774 TTIHKSP------DESTPELSAEPTPKALENSPKEP--GVPTTKTPAA----TKPEMTTT 821 Query: 1104 ----VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSL 1159 + + + + AP T+ + + T+++I+ T T T+P Sbjct: 822 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 881 Query: 1160 SVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPE 1208 +++ LA T +K+IT ++ A+P + P P+ Sbjct: 882 TLKTTTLAP-KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 929 Score = 144 bits (363), Expect = 5e-34 Identities = 165/663 (24%), Positives = 236/663 (35%), Gaps = 108/663 (16%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP--PPPPLPSQSAPSAGSA-APMF 664 P PK TP T +P+P P P P P P P P P P + AP+ AP Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417 Query: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724 K + S K P P +S + P P P P PT Sbjct: 418 TK-----------EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466 Query: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-PQAPPKPLV 783 A P AP+ P+ AP P + AP TP P P P P P +P Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517 Query: 784 TIP---APTSTKTVAPVVTQA-APPTPTPPVP--PAKKQPAFPASYIP-----PSPPTPP 832 T P APT+ K + P + AP TP P P P + P P P P+P TP Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577 Query: 833 VPV------PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME----SQP 882 P PT PK+ + P +P P P+ K+ A P P ++ + P Sbjct: 578 AAAPNTPKEPAPTTPKEPA-----PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632 Query: 883 LKPVPANVAPQS----------PPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP 930 KP P +AP + PA P++ P+P P P P P Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692 Query: 931 PPSPVPAPPPPPPP-------TASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIK 982 P P P P P T PT S P T K ++P K+P PT + Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK---P 749 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 + + E P P V + + P SP + T P +A P P L S PGV Sbjct: 750 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKE-PGVPT 807 Query: 1043 QGCVSAKAPVLSGRGKDSVVE---FPSPPSDSDFPPPPPET----------ELPLPPIEI 1089 +A P ++ KD E +P + + P ET ++ ++ Sbjct: 808 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867 Query: 1090 PAVFSGNTSP------KVAVVNPQPQQWSK----MSVKKAPPPTRPKRNDSTRLTQAEIS 1139 + + +T+P K + P+ K + P T ++ +T + Sbjct: 868 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT--NSKATT 925 Query: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199 +P T P+ PTS K + + R + K+ ++S M PT+ + + Sbjct: 926 PKPQKPTKAPKKPTSTKKPKT--------MPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 977 Query: 1200 MAL 1202 L Sbjct: 978 AML 980 Score = 134 bits (337), Expect = 5e-31 Identities = 165/687 (24%), Positives = 236/687 (34%), Gaps = 96/687 (13%) Query: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL 649 ++K+ + P + PK +P T +P+P P P P P P P P P Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492 Query: 650 PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVV 709 P+ + AP K T + + P TP + K P + Sbjct: 493 PT----TPKEPAPTTTKKPAPTTPKEPA--------PTTPKETAPTTPKKLTPTTPEKLA 540 Query: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769 P P P P TP +A P P+ P+ AP P AP TP P P Sbjct: 541 PTTPEKPAPTTP-EELAPTTPEEPTPTTPEEPAPTTP---------KAAAPNTPKEPAPT 590 Query: 770 ----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825 PAP P+ P APT+ K AP T P PT P PA K+ A P + Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAP--TTLKEPAPTTPKKPAPKELA-PTTTKE 647 Query: 826 PSPPT--PPVPVPP----PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879 P+ T P P P PT PK+ + P +P P P+ K A P P Sbjct: 648 PTSTTCDKPAPTTPKGTAPTTPKEPA-----PTTPKEPAPTTPKGTAPTTLKEPAP---- 698 Query: 880 SQPLKPVPANVAPQSP--PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937 + P KP P +AP + P K P++ +P P P P P P P Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA------PTTPKKPAPT 752 Query: 938 PPPPPPPTAS----PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993 P PPPT S PT K + K+ S+P PTP+ + G P K Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPKEPGV--PTTK 809 Query: 994 RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053 P+ + T A+ + ++ P K+ + ++A + Sbjct: 810 TPAATK--PEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867 Query: 1054 SGRGKDSVVEFP-SPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112 + F + + P T+ + EI PK N S Sbjct: 868 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATN------S 921 Query: 1113 KMSVKKAPPPTR-PKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNR 1171 K + K PT+ PK+ ST+ + + T P+ TS L+ + + Sbjct: 922 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 981 Query: 1172 TLQRKSITRHGSLSSRMSRAE--------------------PTATMDDMALPPPPPE--- 1208 T R + T + L ++E P T D LP P + Sbjct: 982 TTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGII 1041 Query: 1209 ---LLSDQQKAGYGGSHISGYATLRRG 1232 +LSD+ G + G TLR G Sbjct: 1042 INPMLSDETNI-CNGKPVDGLTTLRNG 1067 >gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] Length = 540 Score = 159 bits (401), Expect = 2e-38 Identities = 99/278 (35%), Positives = 146/278 (52%), Gaps = 9/278 (3%) Query: 269 KKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFE 328 KK VI+V+ D++S+ + V T R V L+ K+H W+L E + + +ER E Sbjct: 106 KKQVIKVYSEDETSRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIE 165 Query: 329 DHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEV---LL 385 DHE ++E L NW + +NKL F + KY FKNP Y + + + N E+ + Sbjct: 166 DHELVIEVLSNWGIEEENKLYFRKNYAKYEFFKNPM-YFFPEHMVSFATETNGEISPTQI 224 Query: 386 EECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQL 445 + F SS T PEI G L K+ GKKSWKK YF LR SG+Y+ KG +K R L F + Sbjct: 225 LQMFLSSS-TYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEF 283 Query: 446 DHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKY 505 + ++Y + K+ APT+Y K P + +K LC ++ ++ WV IR+ KY Sbjct: 284 GNSDIYVSLAGKKKHGAPTNYGFCFK-PNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKY 342 Query: 506 GKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSI 543 G QLY NY + +S S S ++S S +S + Sbjct: 343 GMQLYQNYMHPYQGRSGC---SSQSISPMRSISENSLV 377 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 159 bits (401), Expect = 2e-38 Identities = 178/740 (24%), Positives = 273/740 (36%), Gaps = 92/740 (12%) Query: 542 SIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRP 601 S+ E+Q + S+ S S S T + +S +S + ++ +++++ K R + P Sbjct: 118 SVSENQESSSSSSSSSSSSTIR----KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 173 Query: 602 YTSLVPPLSP-----QPKIVTPYTASQPSPPLPPPPP---PPPPPPPPPPPPPPPLPSQS 653 +V K+ TP T++ + P P P P PP ++ Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 233 Query: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP---QILVPPNGVVP 710 + + + K +T T Q ++ K T ++QS++ + L P + V+ Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 288 Query: 711 PPPPPPPPPTPGSAMAQLK-PAPCAPSLPQFSAP--PPPLKIHQVQHI--------TQVA 759 P P T G A+ K P P P P + P P P I T+ A Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 348 Query: 760 PPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 P TP P P PAP P+ P PAPT+TK+ + AP TP P P K Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408 Query: 816 QPAFPASYIPPSPPTPPVPVPP-----PTLPKQQSFCA--KPPPS-PLSPVPSVVKQIA- 866 +PA P + P+P TP P P PT PK+ + A KP P+ P P P+ K+ A Sbjct: 409 EPA-PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467 Query: 867 --SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924 ++ P P TP K P +P K+ P P + + P P+ Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527 Query: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK--PPPTPQRNSSIK 982 P P+P P P P P + P T K +P K P TP++ + Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 PE P+ + TP E +P+ P P P +P P Sbjct: 588 -------PEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPAP------TTPKAAA 632 Query: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102 AP + + P+P + + P P+ P ++ PA T+PK Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP-TTLKEPA----PTTPK-- 685 Query: 1103 VVNPQPQQWSKMSVKK-------APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 P P++ + + K+ P PT PK T ++P T PT+P Sbjct: 686 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKG------TAPTTPKEPAPTTPKEPAPTTP 737 Query: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215 K + P L + T +K + + ++ PT+T D P P E K Sbjct: 738 KGT---APTTLKEPAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPK 791 Query: 1216 AGYGGSHISGYATLRRGPPP 1235 + T PPP Sbjct: 792 EPAPTTPKKPAPTTPETPPP 811 Score = 144 bits (363), Expect = 5e-34 Identities = 165/663 (24%), Positives = 236/663 (35%), Gaps = 108/663 (16%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP--PPPPLPSQSAPSAGSA-APMF 664 P PK TP T +P+P P P P P P P P P P + AP+ AP Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724 K + S K P P +S + P P P P PT Sbjct: 470 TK-----------EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518 Query: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-PQAPPKPLV 783 A P AP+ P+ AP P + AP TP P P P P P +P Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569 Query: 784 TIP---APTSTKTVAPVVTQA-APPTPTPPVP--PAKKQPAFPASYIP-----PSPPTPP 832 T P APT+ K + P + AP TP P P P + P P P P+P TP Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629 Query: 833 VPV------PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME----SQP 882 P PT PK+ + P +P P P+ K+ A P P ++ + P Sbjct: 630 AAAPNTPKEPAPTTPKEPA-----PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684 Query: 883 LKPVPANVAPQS----------PPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP 930 KP P +AP + PA P++ P+P P P P P Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744 Query: 931 PPSPVPAPPPPPPP-------TASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIK 982 P P P P P T PT S P T K ++P K+P PT + Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK---P 801 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 + + E P P V + + P SP + T P +A P P L S PGV Sbjct: 802 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKE-PGVPT 859 Query: 1043 QGCVSAKAPVLSGRGKDSVVE---FPSPPSDSDFPPPPPET----------ELPLPPIEI 1089 +A P ++ KD E +P + + P ET ++ ++ Sbjct: 860 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919 Query: 1090 PAVFSGNTSP------KVAVVNPQPQQWSK----MSVKKAPPPTRPKRNDSTRLTQAEIS 1139 + + +T+P K + P+ K + P T ++ +T + Sbjct: 920 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT--NSKATT 977 Query: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199 +P T P+ PTS K + + R + K+ ++S M PT+ + + Sbjct: 978 PKPQKPTKAPKKPTSTKKPKT--------MPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1029 Query: 1200 MAL 1202 L Sbjct: 1030 AML 1032 Score = 104 bits (260), Expect = 5e-22 Identities = 148/649 (22%), Positives = 219/649 (33%), Gaps = 90/649 (13%) Query: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPM---------------FVKYSTITRLQNASQH 679 P PP PPP SQ+ S +P + +++ Q +S Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128 Query: 680 SGALFKPPTPPVMQS-------QSVKPQILVPPNGV-VPPPPPPPPPPTPGSAMAQLKPA 731 S + T ++S + ++ ++ V N P P PP A + L Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188 Query: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA--PPKPLVTIPAPT 789 + P S K+ IT P P P LPP + + +T+ T Sbjct: 189 DFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRP------SLPPNSDTSKETSLTVNKET 241 Query: 790 STKTVAPVVTQAAPPTP-TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCA 848 + +T T T AK+ + + PT V P PK ++ Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTK 299 Query: 849 KPP-PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP-VPANVAPQSPPAVKAKPKWQP 906 P +P P P+ K+ AS P PTP ++S P P PA +S P +P P Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--AP 357 Query: 907 SSIPVPSPDFP---------PPPPESSLVFPPPPPSPVPAPPPPPPPTA--SPTPDKSGS 955 ++ P+P P P P ++ P P P P P P PT P P Sbjct: 358 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417 Query: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015 P T K +P K+P PT + + + PK P + TP + + +K Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP------APTTPKEPAPTTTK 471 Query: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075 E P P P +P + AP + + P+P + + P Sbjct: 472 E--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529 Query: 1076 PPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQ 1135 P+ P P E PA T+PK P P + K P PT PK Sbjct: 530 TTPKKPAPTTPKE-PA----PTTPK----EPAP------TTTKKPAPTTPK--------- 565 Query: 1136 AEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTA 1195 +P T PT+PK P LA T ++ + T L+ + EPT Sbjct: 566 -----EPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPAPTTPEELAP-TTPEEPTP 617 Query: 1196 TMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNT 1244 T + P P + K + T + P P PK T Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 666 Score = 52.4 bits (124), Expect = 3e-06 Identities = 68/320 (21%), Positives = 102/320 (31%), Gaps = 47/320 (14%) Query: 608 PLSPQPKIVTPYT--------ASQPSPPLPP---PPPPPPPPPPPPPPPPPPLPSQSAPS 656 P P PK + P T + +P+P P P P P P P P P P P+ Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 812 Query: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP 716 + T ++ + + L PTP +++ +P + P P P Sbjct: 813 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV---PTTKTPAATKPE 869 Query: 717 PPPTPGSAMAQ--LKPAP----CAPSLPQFSAPPPPLKIHQ--VQHITQVAPPTPPPPPP 768 T + L+ P AP + + +A TQV T P Sbjct: 870 MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 929 Query: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828 + T+ T T+AP VT T + ++ A P S Sbjct: 930 F-----------KITTL----KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 974 Query: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888 T P P P PK+ + KP P P PTP M S + P Sbjct: 975 ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT----------PTPRKMTSTMPELNPT 1024 Query: 889 NVAPQSPPAVKAKPKWQPSS 908 + ++ +P P+S Sbjct: 1025 SRIAEAMLQTTTRPNQTPNS 1044 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 159 bits (401), Expect = 2e-38 Identities = 178/740 (24%), Positives = 273/740 (36%), Gaps = 92/740 (12%) Query: 542 SIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRP 601 S+ E+Q + S+ S S S T + +S +S + ++ +++++ K R + P Sbjct: 159 SVSENQESSSSSSSSSSSSTIR----KIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 214 Query: 602 YTSLVPPLSP-----QPKIVTPYTASQPSPPLPPPPP---PPPPPPPPPPPPPPPLPSQS 653 +V K+ TP T++ + P P P P PP ++ Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 274 Query: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP---QILVPPNGVVP 710 + + + K +T T Q ++ K T ++QS++ + L P + V+ Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 329 Query: 711 PPPPPPPPPTPGSAMAQLK-PAPCAPSLPQFSAP--PPPLKIHQVQHI--------TQVA 759 P P T G A+ K P P P P + P P P I T+ A Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 389 Query: 760 PPTPPPPPPI----PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 P TP P P PAP P+ P PAPT+TK+ + AP TP P P K Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449 Query: 816 QPAFPASYIPPSPPTPPVPVPP-----PTLPKQQSFCA--KPPPS-PLSPVPSVVKQIA- 866 +PA P + P+P TP P P PT PK+ + A KP P+ P P P+ K+ A Sbjct: 450 EPA-PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508 Query: 867 --SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924 ++ P P TP K P +P K+ P P + + P P+ Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568 Query: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK--PPPTPQRNSSIK 982 P P+P P P P P + P T K +P K P TP++ + Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 PE P+ + TP E +P+ P P P +P P Sbjct: 629 -------PEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPAP------TTPKAAA 673 Query: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102 AP + + P+P + + P P+ P ++ PA T+PK Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP-TTLKEPA----PTTPK-- 726 Query: 1103 VVNPQPQQWSKMSVKK-------APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 P P++ + + K+ P PT PK T ++P T PT+P Sbjct: 727 --KPAPKELAPTTTKEPTSTTCDKPAPTTPKG------TAPTTPKEPAPTTPKEPAPTTP 778 Query: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215 K + P L + T +K + + ++ PT+T D P P E K Sbjct: 779 KGT---APTTLKEPAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPK 832 Query: 1216 AGYGGSHISGYATLRRGPPP 1235 + T PPP Sbjct: 833 EPAPTTPKKPAPTTPETPPP 852 Score = 144 bits (363), Expect = 5e-34 Identities = 165/663 (24%), Positives = 236/663 (35%), Gaps = 108/663 (16%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP--PPPPLPSQSAPSAGSA-APMF 664 P PK TP T +P+P P P P P P P P P P + AP+ AP Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724 K + S K P P +S + P P P P PT Sbjct: 511 TK-----------EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559 Query: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-PQAPPKPLV 783 A P AP+ P+ AP P + AP TP P P P P P +P Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTP---------KEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610 Query: 784 TIP---APTSTKTVAPVVTQA-APPTPTPPVP--PAKKQPAFPASYIP-----PSPPTPP 832 T P APT+ K + P + AP TP P P P + P P P P+P TP Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670 Query: 833 VPV------PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME----SQP 882 P PT PK+ + P +P P P+ K+ A P P ++ + P Sbjct: 671 AAAPNTPKEPAPTTPKEPA-----PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725 Query: 883 LKPVPANVAPQS----------PPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP 930 KP P +AP + PA P++ P+P P P P P Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785 Query: 931 PPSPVPAPPPPPPP-------TASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIK 982 P P P P P T PT S P T K ++P K+P PT + Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK---P 842 Query: 983 SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 + + E P P V + + P SP + T P +A P P L S PGV Sbjct: 843 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKE-PGVPT 900 Query: 1043 QGCVSAKAPVLSGRGKDSVVE---FPSPPSDSDFPPPPPET----------ELPLPPIEI 1089 +A P ++ KD E +P + + P ET ++ ++ Sbjct: 901 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960 Query: 1090 PAVFSGNTSP------KVAVVNPQPQQWSK----MSVKKAPPPTRPKRNDSTRLTQAEIS 1139 + + +T+P K + P+ K + P T ++ +T + Sbjct: 961 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT--NSKATT 1018 Query: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199 +P T P+ PTS K + + R + K+ ++S M PT+ + + Sbjct: 1019 PKPQKPTKAPKKPTSTKKPKT--------MPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1070 Query: 1200 MAL 1202 L Sbjct: 1071 AML 1073 Score = 104 bits (260), Expect = 5e-22 Identities = 148/649 (22%), Positives = 219/649 (33%), Gaps = 90/649 (13%) Query: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPM---------------FVKYSTITRLQNASQH 679 P PP PPP SQ+ S +P + +++ Q +S Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169 Query: 680 SGALFKPPTPPVMQS-------QSVKPQILVPPNGV-VPPPPPPPPPPTPGSAMAQLKPA 731 S + T ++S + ++ ++ V N P P PP A + L Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229 Query: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA--PPKPLVTIPAPT 789 + P S K+ IT P P P LPP + + +T+ T Sbjct: 230 DFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRP------SLPPNSDTSKETSLTVNKET 282 Query: 790 STKTVAPVVTQAAPPTP-TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCA 848 + +T T T AK+ + + PT V P PK ++ Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTK 340 Query: 849 KPP-PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP-VPANVAPQSPPAVKAKPKWQP 906 P +P P P+ K+ AS P PTP ++S P P PA +S P +P P Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--AP 398 Query: 907 SSIPVPSPDFP---------PPPPESSLVFPPPPPSPVPAPPPPPPPTA--SPTPDKSGS 955 ++ P+P P P P ++ P P P P P P PT P P Sbjct: 399 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458 Query: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015 P T K +P K+P PT + + + PK P + TP + + +K Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP------APTTPKEPAPTTTK 512 Query: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075 E P P P +P + AP + + P+P + + P Sbjct: 513 E--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570 Query: 1076 PPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQ 1135 P+ P P E PA T+PK P P + K P PT PK Sbjct: 571 TTPKKPAPTTPKE-PA----PTTPK----EPAP------TTTKKPAPTTPK--------- 606 Query: 1136 AEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTA 1195 +P T PT+PK P LA T ++ + T L+ + EPT Sbjct: 607 -----EPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPAPTTPEELAP-TTPEEPTP 658 Query: 1196 TMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNT 1244 T + P P + K + T + P P PK T Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 707 Score = 52.4 bits (124), Expect = 3e-06 Identities = 68/320 (21%), Positives = 102/320 (31%), Gaps = 47/320 (14%) Query: 608 PLSPQPKIVTPYT--------ASQPSPPLPP---PPPPPPPPPPPPPPPPPPLPSQSAPS 656 P P PK + P T + +P+P P P P P P P P P P P+ Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 853 Query: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP 716 + T ++ + + L PTP +++ +P + P P P Sbjct: 854 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV---PTTKTPAATKPE 910 Query: 717 PPPTPGSAMAQ--LKPAP----CAPSLPQFSAPPPPLKIHQ--VQHITQVAPPTPPPPPP 768 T + L+ P AP + + +A TQV T P Sbjct: 911 MTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 970 Query: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828 + T+ T T+AP VT T + ++ A P S Sbjct: 971 F-----------KITTL----KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 1015 Query: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888 T P P P PK+ + KP P P PTP M S + P Sbjct: 1016 ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT----------PTPRKMTSTMPELNPT 1065 Query: 889 NVAPQSPPAVKAKPKWQPSS 908 + ++ +P P+S Sbjct: 1066 SRIAEAMLQTTTRPNQTPNS 1085 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 158 bits (400), Expect = 3e-38 Identities = 148/498 (29%), Positives = 193/498 (38%), Gaps = 137/498 (27%) Query: 624 PSPPLPPPPPPPPPPP---PPPPPPPPPLPSQSAPSAGSAAP-----MFVKYSTITRLQN 675 P PP PPPP PPPPPP PPPPPP P S S A P + TRL+ Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61 Query: 676 ASQ-----------------------HSGALFKPPTP--------PVMQ----------- 693 +Q ++ PPT PV++ Sbjct: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGK 121 Query: 694 ------SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747 S++ P++ PN + P PP P G+ A AP P APPP Sbjct: 122 TGQGPGSRAPSPRL---PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP-- 176 Query: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK-PLVTIPAPTSTKTVAPVVTQAAPPTP 806 P PPPPPP+P PLP +P K PLV+ P P TK PVV APP P Sbjct: 177 ------------PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPL-TKGNLPVV---APPVP 220 Query: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866 P PP PP PPTPP P+PP ++ ++ + P L P+P + + Sbjct: 221 CAPPPPP-----------PPPPPTPP-PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL- 267 Query: 867 SQFPPPPTPPAMESQPLKPV-----PANVAPQSPPAVKAKPKWQPSSIPVP----SPDFP 917 PP P ++++P P P P PP P+ + P+P S + P Sbjct: 268 ----PPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323 Query: 918 PP-PPES-SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-KPPPT 974 PP PP+S S PP P PP PP + P K K+ + + GGK PPP Sbjct: 324 PPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK-----KRHGRPGAGGGKLNPPPA 378 Query: 975 PQRNS-----SIKSSSGAEHPEPKRPS----------VDSLVSKFT-------PPAESGS 1012 P S S KS ++P +D SKFT PP + Sbjct: 379 PPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYK 438 Query: 1013 PSKETLP---PPAAPPKP 1027 P ++ P P + P P Sbjct: 439 PCQKIYPSKIPRSRTPGP 456 Score = 100 bits (250), Expect = 7e-21 Identities = 134/494 (27%), Positives = 176/494 (35%), Gaps = 103/494 (20%) Query: 709 VPPPPPPPPP-PTPGSAMAQLKPAPCAPSLPQFSAPPPPLK-------------IHQVQH 754 +P PPPPPPP P P + P P PS P S L+ I Q Sbjct: 1 MPVPPPPPPPLPPPPPPLG--APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58 Query: 755 ITQVAPPTPPPPPPIP-----------------APLPPQAPPKPLVTIPA--PTSTKTVA 795 + +V P I A PP P P + VA Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118 Query: 796 PVVTQAAP----PTPT--------PPVPPAK------------KQPAFPASYIP-PSPPT 830 T P P+P P +PPA + A P +P P PPT Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178 Query: 831 PPVPVP--PPTLPKQQSFCAK--PPPSPLSP--VPSVVKQIASQFPPPPTPPAMESQPLK 884 PP P P PP LP PP PL+ +P V + PPPP PP Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP-------P 231 Query: 885 PVPANVAPQSPPAVKA-KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV------PA 937 P P + P S + KA KP+ P +P P P PP P SP PA Sbjct: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA 291 Query: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS---SSGAEH-PEPK 993 PPPP PP AS +P ++ P +S + PPP P ++ S ++ +GA+ P P Sbjct: 292 PPPPLPPYASCSP-RASLPAPPLPGVNS-SSETPPPLPPKSPSFQAPPQKAGAQALPAPP 349 Query: 994 RPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP-----------GVLQ 1042 P + G+ + PPPA P + LS + G L+ Sbjct: 350 APPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLR 409 Query: 1043 QGCVSAKAPVLSGRGKDSVVEFPSP----PSDSDFPPPPPETELPLPPIEIPAVFSGNTS 1098 G + S SV +FP P P +P P + P P ++ AV G +S Sbjct: 410 NGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAV--GQSS 467 Query: 1099 PKVAVVNPQPQQWS 1112 + N Q Q S Sbjct: 468 DDIKGRNSQVTQAS 481 Score = 98.6 bits (244), Expect = 3e-20 Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 87/380 (22%) Query: 553 QSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQ 612 ++ G P+ + +++I + A R E+ A + RP PP +P Sbjct: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180 Query: 613 PK---IVTPYTASQP------SPP-----------LPPPPPPPPPPPPPPPPPPPPLPSQ 652 P + P +S P SPP PP P PPPPPPPPPP PPPLP Sbjct: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA 240 Query: 653 SAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP 712 S V+ ++VKPQ+ P + P P Sbjct: 241 S-------------------------------------VLSDKAVKPQL--APLHLPPIP 261 Query: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772 PP P P G + +PA A + APPPPL + +P P PP+P Sbjct: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY-----ASCSPRASLPAPPLPGV 316 Query: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK---------QPAFPASY 823 P PL P S AP A P PP PP + +P Sbjct: 317 NSSSETPPPL----PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372 Query: 824 IPPSPPTPPVPVPPPTL--PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT------- 874 + P PP PP P L QQ+ P P + + I F T Sbjct: 373 LNP-PPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDF 431 Query: 875 PPAMESQPLKPVPANVAPQS 894 PP E +P + + + P+S Sbjct: 432 PPPDEYKPCQKIYPSKIPRS 451 Score = 85.5 bits (210), Expect = 3e-16 Identities = 109/427 (25%), Positives = 156/427 (36%), Gaps = 46/427 (10%) Query: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM----ESQ 881 P PP PP+P PPP L A PPP P +P S + P + + Sbjct: 4 PPPPPPPLPPPPPPLG------APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57 Query: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 L+ V + +S P +++ + PP +F P PA Sbjct: 58 RLRKV-TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001 + S +P + + G PP +P R + + GA P RP+V + Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASP-RLGNTSEAHGAARTAPPRPNVPA-- 173 Query: 1002 SKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV 1061 PP + P LPPP P K L V+ PG L +G + AP V Sbjct: 174 ----PPPPTPPPPPPPLPPPLPSSSPIKTPL--VSPPGPLTKGNLPVVAP--------PV 219 Query: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPP 1121 P PP PPPPP T PLPP + + P++A ++ P + PP Sbjct: 220 PCAPPPP-----PPPPPPTPPPLPPASV--LSDKAVKPQLAPLHLPP---IPPPLPLLPP 269 Query: 1122 PTRPKRNDSTRLTQAEISEQPTMATVVPQVPT-SPKSSLSVQPGFLADLNRTLQRKSITR 1180 P + E P +P + SP++SL P L +N + + Sbjct: 270 CGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP--LPGVNSSSETPPPLP 327 Query: 1181 HGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKR 1240 S S + + A + PP PP QK +G G + PPPAPP R Sbjct: 328 PKSPSFQAPPQKAGAQA--LPAPPAPPGSQPFLQKKRHGRPGAGGG---KLNPPPAPPAR 382 Query: 1241 DQNTKLS 1247 T+LS Sbjct: 383 SPTTELS 389 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 155 bits (392), Expect = 2e-37 Identities = 122/429 (28%), Positives = 162/429 (37%), Gaps = 65/429 (15%) Query: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPP---PPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P K +T PSPP P PPP PP P PP + + P + +P Sbjct: 1391 PMDKCITT-----PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPI--- 1442 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP------PPPPPPPTP 721 +T T + S + TPP + S PP PP PPP P+P Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502 Query: 722 GSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781 + + P +LP + P PP T PPT P PP P+ P Sbjct: 1503 PTT-TPITPPASTTTLPPTTTPSPPTT------TTTTPPPTTTPSPPTTTPITP------ 1549 Query: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPP-TL 840 PTST T+ P T + PPT T PP P + PSPPT PPP T Sbjct: 1550 ------PTSTTTLPPTTTPSPPPTTTTTPPPTTTPS--PPTTTTPSPPTITTTTPPPTTT 1601 Query: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900 P + PP +P PP T P +P P PP Sbjct: 1602 PSPPTTTTTTPPPTTTP------------SPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649 Query: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPP---PPSPVPAPPPPPPPTASPTPDKSGSPG 957 P P++ P P P PP ++ PPP P SP+ P PP T + TP + +P Sbjct: 1650 TP--PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT-TPSPTTTPS 1706 Query: 958 KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET 1017 + T++P P P +++ + S P P ++ +L PP + SP T Sbjct: 1707 SPITTTTTPSSTTTPSPPP--TTMTTPSPTTTPSPPTTTMTTL-----PPTTTSSPLTTT 1759 Query: 1018 -LPPPAAPP 1025 LPP PP Sbjct: 1760 PLPPSITPP 1768 Score = 143 bits (361), Expect = 9e-34 Identities = 117/433 (27%), Positives = 152/433 (35%), Gaps = 70/433 (16%) Query: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746 P+PP + ++ P P PPP P+P P + P + P PP Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP--------PITTTTTPPPTTTPSPP 1457 Query: 747 LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806 + T PPT P PP P PP P P PT+T T P T +PPT Sbjct: 1458 IST------TTTPPPTTTPSPPTTTPSPPTTTPSP------PTTTTTTPPPTTTPSPPTT 1505 Query: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866 TP PPA P + PSPPT PPPT P P +P+ Sbjct: 1506 TPITPPASTTTLPPTT--TPSPPTTTTTTPPPT--------TTPSPPTTTPI-------- 1547 Query: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926 TPP + +P P PP P P++ P P P PP + Sbjct: 1548 -------TPPTSTTT----LPPTTTPSPPPTTTTTPP--PTTTPSPPTTTTPSPPTITTT 1594 Query: 927 FPPPPPSPVPAPPPP------PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980 PPP P PP PPPT +P+P + TS T+ P P P P ++ Sbjct: 1595 TPPP----TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650 Query: 981 IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETL--PPPAAPPKPGKLNLSGVNLP 1038 ++ P PS + PP + S T PP P + Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710 Query: 1039 GVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP-----PETELPLPPIEIPAVF 1093 + +P + S PSPP+ + PP P T PLPP P F Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770 Query: 1094 S--GNTSPKVAVV 1104 S T+P V Sbjct: 1771 SPFSTTTPTTPCV 1783 Score = 133 bits (335), Expect = 9e-31 Identities = 114/419 (27%), Positives = 147/419 (35%), Gaps = 54/419 (12%) Query: 755 ITQVAPPT--PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812 IT +PPT P PPP LPP P P PT+T T P T +PP T PP Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSP------PTTTTTTPPPTTTPSPPITTTTTPP 1449 Query: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872 P+ P S PPT P PP T P + PP + + P PP Sbjct: 1450 PTTTPSPPISTTTTPPPTT-TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP-----SPP 1503 Query: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932 T P +P P P P P++ P P P PP S+ PP Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPP--- 1558 Query: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP---GGKKPPPT-----PQRNSSIKSS 984 P PPPT + TP + +P T+ T SP PPPT P ++ Sbjct: 1559 ----TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614 Query: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGS--PSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042 + P P + PP + S P+ T PPP P P + Sbjct: 1615 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPI----- 1669 Query: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102 + P + + PSPP+ + P P T P PI S T+P Sbjct: 1670 ---TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSP--TTTPSSPITTTTTPSSTTTP--- 1721 Query: 1103 VVNPQPQQWSKMSVKKAPPP------TRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 +P P + S P P T P S+ LT + T T P T+P Sbjct: 1722 --SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP 1778 Score = 115 bits (287), Expect = 3e-25 Identities = 92/324 (28%), Positives = 120/324 (37%), Gaps = 39/324 (12%) Query: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662 T+ P +P P TP T + LPP P PP PPP + PS + P Sbjct: 1492 TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT-----TTPSPPTTTP 1546 Query: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722 + ST T L + S TPP + S P + PPP P+P Sbjct: 1547 ITPPTSTTT-LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605 Query: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPL 782 + P PS P + PP T + P T P PPP PP P Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTS------TTTLPPTTTPSPPPTTTTTPP-----PT 1654 Query: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI-PPSP-PTPPVPVPPPTL 840 T PT+T P+ T PP T P P P+ P + + PSP TP P+ T Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714 Query: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT------PPAMESQPLKPVPANVAPQS 894 P + + PP + +P P+ P PPT PP S PL P Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTTT-------PSPPTTTMTTLPPTTTSSPLTTTPL------ 1761 Query: 895 PPAVKAKPKWQPSSIPVPSPDFPP 918 PP++ P + P S P+ P Sbjct: 1762 PPSI-TPPTFSPFSTTTPTTPCVP 1784 Score = 113 bits (283), Expect = 1e-24 Identities = 102/411 (24%), Positives = 139/411 (33%), Gaps = 68/411 (16%) Query: 798 VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL-PKQQSFCAKPPPSPLS 856 +T +PPT TP PP P + PSPPT PPPT P PP + Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTT--TPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT 1453 Query: 857 PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDF 916 P P + + PPP T P+ + P P P P P P++ P P Sbjct: 1454 PSPPIS---TTTTPPPTTTPSPPTTT--PSPPTTTPSPPTTTTTTPP--PTTTPSPPTTT 1506 Query: 917 PPPPPESSLVFPPPP-PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975 P PP S+ PP PSP PPPT +P+P + TS T+ P P P P Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566 Query: 976 QRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV 1035 ++ ++ P PS ++ + PP + SP T P PP Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP--PP---------- 1614 Query: 1036 NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSG 1095 PSPP+ + PP T LP P + Sbjct: 1615 --------------------------TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1648 Query: 1096 NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 T P +P P T P +T T + + T P PT+ Sbjct: 1649 TTPPPTTTPSP-------------PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695 Query: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPP 1206 ++ S + + T S T + M+ PT T P PP Sbjct: 1696 MTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT------PSPP 1740 Score = 94.4 bits (233), Expect = 6e-19 Identities = 122/572 (21%), Positives = 179/572 (31%), Gaps = 54/572 (9%) Query: 612 QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS-APSAGSAAPMFVKYSTI 670 QP +T T P+PP P P P P P+ + + + P T Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940 Query: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP---PPPPPTPGSAMAQ 727 T + + PTP Q+ + P + V P P P P TP + Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTT 1998 Query: 728 LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPPQAPPKPL 782 + P P P+ Q P IT TP P P P P+ P Sbjct: 1999 VTPTP-TPTGTQTPTTTP---------ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2048 Query: 783 VTIPAPTSTKTVAPV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841 T P T T T P+ T PTPTP + PTP P T P Sbjct: 2049 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107 Query: 842 KQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANVAPQSPPA 897 + P P+P I + P PTP ++ P+ V P P Sbjct: 2108 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2167 Query: 898 VKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPPPP----- 944 P P + P P+P P P ++ P P+P P P Sbjct: 2168 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2227 Query: 945 TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF 1004 T +PTP +G+ T+ ++ P PTP + P + + + Sbjct: 2228 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPITTTTTVT 2276 Query: 1005 TPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEF 1064 P +G+ + T P +G P + P + G + Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336 Query: 1065 PSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122 P + + P P P T+ P PI + +P + +V P P Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2396 Query: 1123 TRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 T + +T +T + PT Q PT+ Sbjct: 2397 TGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2427 Score = 94.0 bits (232), Expect = 8e-19 Identities = 138/670 (20%), Positives = 204/670 (30%), Gaps = 83/670 (12%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3672 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3673 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3729 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3790 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3848 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3849 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3908 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3968 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS------IKSSSGAEHPE 991 P T +PTP +G+ T+ ++ P PTP + +++ P Sbjct: 3969 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4028 Query: 992 P---KRPSVDSLVSKFT---PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGC 1045 P + P+ + + T P +G+ + T P +G P Sbjct: 4029 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088 Query: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE----------------TELPLP---- 1085 + P + G + P + + P P P T P P Sbjct: 4089 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4148 Query: 1086 -PIEIPAVFSGNTSPKVAVVNPQPQQWSKM----SVKKAPPPTRPKRNDSTRLTQAEISE 1140 P P + +P Q + + +V P PT + T + A I+E Sbjct: 4149 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE 4208 Query: 1141 ----QPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTAT 1196 P + PQ S S L+ L+ L ++ S + ++ PT T Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA------PTTT 4262 Query: 1197 MDDMALPPPP 1206 L PPP Sbjct: 4263 SGGHTLSPPP 4272 Score = 92.8 bits (229), Expect = 2e-18 Identities = 74/261 (28%), Positives = 95/261 (36%), Gaps = 62/261 (23%) Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP----PPPPPLPSQSAPS 656 P T+ PP + P +P T + PSPP PPP P PP PPP + S P+ Sbjct: 1566 PTTTTTPPPTTTP---SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622 Query: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP 716 P TPP + +PP P Sbjct: 1623 T---------------------------TPITPPTSTT-------------TLPPTTTPS 1642 Query: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776 PPPT + P PS P + P PP+ T PPT P PI Sbjct: 1643 PPPTTTTT----PPPTTTPSPPTTTTPSPPIT------TTTTPPPTTTPSSPITT---TP 1689 Query: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836 +PP +T P+PT+T + +P+ T P + T P PP P+ PSPPT + Sbjct: 1690 SPPTTTMTTPSPTTTPS-SPITTTTTPSSTTTPSPPPTTMTT-PSPTTTPSPPTTTMTTL 1747 Query: 837 PPTLPKQQSFCAKPPPSPLSP 857 PPT PPS P Sbjct: 1748 PPTTTSSPLTTTPLPPSITPP 1768 Score = 92.8 bits (229), Expect = 2e-18 Identities = 120/577 (20%), Positives = 177/577 (30%), Gaps = 50/577 (8%) Query: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669 +P P TP T + P P P P P P+ + G+ P +T Sbjct: 1892 NPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITT 1949 Query: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPTPG 722 T + +G P T P+ + +V P P G P P P PTP Sbjct: 1950 TTTVTPTPTPTGTQ-TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPT 2006 Query: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPPQA 777 + + P + IT TP P P P P+ Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066 Query: 778 PPKPLVTIPAPTSTKTVAPV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836 P T P T T T P+ T PTPTP + PTP Sbjct: 2067 TVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2125 Query: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANVAP 892 P T P + P P+P I + P PTP ++ P+ V P Sbjct: 2126 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185 Query: 893 QSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944 P P P + P P+P P P ++ P P+P P P Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245 Query: 945 -----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDS 999 T +PTP +G+ T+ ++ P PTP + P + + Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPITT 2294 Query: 1000 LVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKD 1059 + P +G+ + T P +G P + P + G Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2354 Query: 1060 SVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117 + P + + P P P T+ P PI + +P + +V Sbjct: 2355 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414 Query: 1118 KAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 P PT + +T +T + PT Q PT+ Sbjct: 2415 PTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2450 Score = 91.3 bits (225), Expect = 5e-18 Identities = 127/541 (23%), Positives = 173/541 (31%), Gaps = 71/541 (13%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3948 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3949 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 4005 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4065 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 4066 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4124 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--FPPPPTPPAMESQPLKPVPAN--V 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 4125 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4184 Query: 891 APQ-SPPAVKAKPKWQPSSIPVPSPDFPPPPPESS-----------------LVFPPPPP 932 P +P + P S+ P+ PPPESS L+ PP Sbjct: 4185 TPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA 4244 Query: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992 + + PP PTA T + S T+SP P TP R ++ SSS P P Sbjct: 4245 IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP-----PGTPTRGTTTGSSSA---PTP 4296 Query: 993 KRPSVDSLVSKFTP-PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 + S +TP P +PS + P P S V + VL + Sbjct: 4297 STVQTTT-TSAWTPTPTPLSTPS--IIRTTGLRPYP-----SSVLICCVLNDTYYAPGEE 4348 Query: 1052 VLSGRGKDS----------VVEFPS---PPSDSDFPPPPPETELPLPPIEIPAVFSGNTS 1098 V +G D+ +EF + P + S P P T P P P+ + T Sbjct: 4349 VYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTK 4408 Query: 1099 P 1099 P Sbjct: 4409 P 4409 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPI 1970 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 1971 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPT 2027 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087 Query: 776 QAPPKPLVTIPAPTSTKTVAPV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2088 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2146 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2147 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2206 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2207 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2315 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2375 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2435 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 2436 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2473 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2016 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2017 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2073 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2134 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2192 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2252 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2253 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2361 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 2482 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2519 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2154 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2155 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2211 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2272 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2499 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 2620 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2657 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2292 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2293 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2349 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2410 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2528 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2637 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2697 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 2758 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2795 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2430 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2431 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2487 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2548 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2606 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2666 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2775 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2835 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 2896 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 2933 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2568 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2569 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2625 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2686 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2804 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 2913 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2973 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3034 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3071 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2706 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2707 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2763 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2824 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2942 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3051 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3172 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3209 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2844 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2845 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 2901 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 2962 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3189 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3249 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3310 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3347 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2982 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 2983 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3039 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3100 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3218 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3327 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3387 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3447 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3448 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3485 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3120 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3121 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3177 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3238 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3356 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3465 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3466 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3525 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3586 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3623 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3258 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3259 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3315 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3376 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3494 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3603 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3663 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3724 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3761 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3396 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3397 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3453 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3514 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3632 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3741 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3861 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 3862 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 3899 Score = 90.9 bits (224), Expect = 7e-18 Identities = 120/579 (20%), Positives = 176/579 (30%), Gaps = 50/579 (8%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3534 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3535 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3591 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 3652 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANV 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770 Query: 891 APQSPPAVKAKPKWQP-----SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P P Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830 Query: 943 PP-----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997 P T +PTP +G+ T+ ++ P PTP + P + Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPI 3879 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 + + P +G+ + T P +G P + P + G Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939 Query: 1058 KDSVVEFPSPPSDSDFPPPPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 + P + + P P P T+ P PI + +P + + Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3999 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154 V P PT + +T +T + PT Q PT+ Sbjct: 4000 VTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTT 4037 Score = 87.8 bits (216), Expect = 6e-17 Identities = 128/593 (21%), Positives = 181/593 (30%), Gaps = 72/593 (12%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 3902 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP-------PPPPT 720 +T T + +G P T P+ + +V P P G P P P PT Sbjct: 3903 TTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPT 3959 Query: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP-----PIPAPLPP 775 P + + P + IT TP P P P P+ Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAA-PPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 P T P T T T P+ T PTPTP + PTP Sbjct: 4020 TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4078 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--FPPPPTPPAMESQPLKPVPAN--V 890 P T P + P P+P I + P PTP ++ P+ V Sbjct: 4079 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4138 Query: 891 APQSPPAVKAKPKWQPSSI-----PVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPP 942 P P P P + P P+P P P ++ P P+P PP Sbjct: 4139 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPP 4198 Query: 943 PPT-ASP-------TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994 T +P P S + + TSSP + +I+ +S A P Sbjct: 4199 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 4258 Query: 995 PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLS 1054 P+ S +PP + T PP P + S P +Q SA P + Sbjct: 4259 PTTTSGGHTLSPPPST------TTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312 Query: 1055 GRGKDSVVEF----PSPPS-------DSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV 1103 S++ P P S + + P E V++G Sbjct: 4313 PLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEE------------VYNGTYGDTCYF 4360 Query: 1104 VNPQ---PQQWSKMSVKKAPPPT-RPKRNDSTRLTQAEISEQPTMATVVPQVP 1152 VN ++ S P PT P ++ T + +PT T P+ P Sbjct: 4361 VNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413 Score = 84.0 bits (206), Expect = 8e-16 Identities = 129/621 (20%), Positives = 187/621 (30%), Gaps = 89/621 (14%) Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP---PPPPPLPSQSAPSA 657 P T+ PP + P +P T + PSPP+ PPP P P P PP + + PS Sbjct: 1645 PTTTTTPPPTTTP---SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSP 1701 Query: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV-----VPPP 712 + + +T P+P S +PP P Sbjct: 1702 TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL 1761 Query: 713 PPPPPPPTPGSAMAQLKPAPCAP----------SLPQFSAPPPPLKIHQVQHITQVAPPT 762 PP PPT PC P P F P ++ I V P Sbjct: 1762 PPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTEL-----IGDVCGPG 1816 Query: 763 PPPPPPIPAPLPPQAP----------------------PKPLVTIPAPTSTKTVAPV--- 797 A + P P KP IP V Sbjct: 1817 WAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCC 1876 Query: 798 --VTQAAPPTPTP---PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852 VTQ T T P PP P + + P+P TP P T P + P P Sbjct: 1877 ECVTQPTTMTTTTTENPTPPTTT-PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 1934 Query: 853 SPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLKPV--PANVAPQSPPAVKAKPKWQP-- 906 +P I + P PTP ++ P+ V P P P P Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994 Query: 907 ---SSIPVPSP---DFPPPPPESSLVFPPPPPSPVPAPPPPPPP-----TASPTPDKSGS 955 + P P+P P P ++ P P+P P P T +PTP +G+ Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2054 Query: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015 T+ ++ P PTP + P + + + P +G+ + Sbjct: 2055 QTPTTTPITTTTTVTPTPTPTGTQT-----------PTTTPITTTTTVTPTPTPTGTQTP 2103 Query: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075 T P +G P + P + G + P + + P Sbjct: 2104 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2163 Query: 1076 PPPE-TELP-LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRL 1133 P P T+ P PI + +P + +V P PT + +T + Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223 Query: 1134 TQAEISEQPTMATVVPQVPTS 1154 T + PT Q PT+ Sbjct: 2224 T-TTTTVTPTPTPTGTQTPTT 2243 Score = 78.2 bits (191), Expect = 5e-14 Identities = 89/376 (23%), Positives = 125/376 (33%), Gaps = 52/376 (13%) Query: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP--PSPVPAPPPPP 942 P+ + SPP P P+S P P PP ++ PPP PSP P Sbjct: 1391 PMDKCITTPSPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448 Query: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002 PPT +P+P S + + T SP P P P S +++ P PS + + Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSP-PTTTPSPPTTTTTTPPPTTTPSPPT-TT 1506 Query: 1003 KFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062 TPPA S TLPP P P + P + + Sbjct: 1507 PITPPA-----STTTLPPTTTPSPPTT----------------TTTTPPPTTTPSPPTTT 1545 Query: 1063 EFPSPPSDSDFPP-----PPPETELPLPPIEIPAVFSGNT--SPKVAVVNPQPQQWSK-- 1113 P S + PP PPP T PP P+ + T P + P P Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605 Query: 1114 -MSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP--QVPTSPKSSLSVQPGFLADLN 1170 + PP T P +T +T PT T +P P+ P ++ + P Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPIT------PPTSTTTLPPTTTPSPPPTTTTTPPP-----T 1654 Query: 1171 RTLQRKSITRHGSLSSRMSRAEPTATMDD--MALPPPPPELLSDQQKAGYGGSHISGYAT 1228 T + T + + PT T P PP ++ S I+ T Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714 Query: 1229 LRRGPPPAPPKRDQNT 1244 P+PP T Sbjct: 1715 PSSTTTPSPPPTTMTT 1730 Score = 60.5 bits (145), Expect = 1e-08 Identities = 84/375 (22%), Positives = 116/375 (30%), Gaps = 86/375 (22%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667 P Q TP T + P P P P P P+ + G+ P Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 4132 Query: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP---PPPPTPGSA 724 +T T + PTP Q+ + P + V P P P P TP + Sbjct: 4133 TTTTTVTPT----------PTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITT 4180 Query: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVT 784 + P P P+ Q + PP + +T T PPP P ++ PL Sbjct: 4181 TTTVTPTP-TPTGTQ-TGPPTHTSTAPIAELT-----TSNPPPESSTPQTSRSTSSPLTE 4233 Query: 785 IPAPTSTKTVAPVVTQAAPP-TPTPPVPPAKKQPAFPASYIPPSPPTPPV---------P 834 ST A +T APP TPT P + P SPP P Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293 Query: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP---------------------- 872 P T+ + P P+PLS PS+++ + P Sbjct: 4294 PTPSTVQTTTTSAWTPTPTPLS-TPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNG 4352 Query: 873 ------------------------PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS 908 P+ P+ P K P P P + +KP P + Sbjct: 4353 TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPT---PSKPSSTPSKPT--PGT 4407 Query: 909 IPVPSPDFPPPPPES 923 P PDF PP E+ Sbjct: 4408 KPPECPDFDPPRQEN 4422 Score = 36.2 bits (82), Expect = 0.20 Identities = 44/203 (21%), Positives = 68/203 (33%), Gaps = 18/203 (8%) Query: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP---PPPPPPPP 644 E S+ S + P T LS P + + + PS P P PPP Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT 4276 Query: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP--TPPVMQSQSVKPQ-- 700 PP P++ + S+AP T + +Q + + P TP ++++ ++P Sbjct: 4277 SPPGTPTRGTTTGSSSAP------TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 4330 Query: 701 ---ILVPPNGVVPPPPPPPPPPTPGSAMAQLK-PAPCAPSLPQFSAPPPPLKIHQVQHIT 756 I N P T G + C +S P P T Sbjct: 4331 SVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 4390 Query: 757 QV-APPTPPPPPPIPAPLPPQAP 778 + P+ P P P PP+ P Sbjct: 4391 PTPSKPSSTPSKPTPGTKPPECP 4413 >gi|48762697 growth factor receptor-bound protein 10 isoform c [Homo sapiens] Length = 536 Score = 152 bits (384), Expect = 2e-36 Identities = 95/292 (32%), Positives = 150/292 (51%), Gaps = 7/292 (2%) Query: 273 IRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHEN 332 ++V D +SK + + T R + L+ KSHC W+LVE L +ER EDHE Sbjct: 112 VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHEL 171 Query: 333 LVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGS 392 +V+ + T S++K +F + KY FKNP N+ + T + L + F S Sbjct: 172 VVQ--VESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS 229 Query: 393 SVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYY 452 S + PEI+G L +K+ GKKSWKK Y LR SG+Y KG +K R L L+ N++ Sbjct: 230 S-SCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 288 Query: 453 GQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMN 512 R +Y APTD+ L +K +++ +++ ++ LC +D +T W+ R+ KYG LY N Sbjct: 289 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 348 Query: 513 YQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPA 564 Y+ +R S S+ ++S S +S + S + + ++ Q A Sbjct: 349 YRIPQQRKA----LLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSA 396 >gi|48762695 growth factor receptor-bound protein 10 isoform c [Homo sapiens] Length = 536 Score = 152 bits (384), Expect = 2e-36 Identities = 95/292 (32%), Positives = 150/292 (51%), Gaps = 7/292 (2%) Query: 273 IRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHEN 332 ++V D +SK + + T R + L+ KSHC W+LVE L +ER EDHE Sbjct: 112 VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHEL 171 Query: 333 LVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGS 392 +V+ + T S++K +F + KY FKNP N+ + T + L + F S Sbjct: 172 VVQ--VESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS 229 Query: 393 SVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYY 452 S + PEI+G L +K+ GKKSWKK Y LR SG+Y KG +K R L L+ N++ Sbjct: 230 S-SCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 288 Query: 453 GQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMN 512 R +Y APTD+ L +K +++ +++ ++ LC +D +T W+ R+ KYG LY N Sbjct: 289 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 348 Query: 513 YQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPA 564 Y+ +R S S+ ++S S +S + S + + ++ Q A Sbjct: 349 YRIPQQRKA----LLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSA 396 >gi|48762679 growth factor receptor-bound protein 10 isoform a [Homo sapiens] Length = 594 Score = 152 bits (384), Expect = 2e-36 Identities = 95/292 (32%), Positives = 150/292 (51%), Gaps = 7/292 (2%) Query: 273 IRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHEN 332 ++V D +SK + + T R + L+ KSHC W+LVE L +ER EDHE Sbjct: 170 VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHEL 229 Query: 333 LVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGS 392 +V+ + T S++K +F + KY FKNP N+ + T + L + F S Sbjct: 230 VVQ--VESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNS 287 Query: 393 SVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYY 452 S + PEI+G L +K+ GKKSWKK Y LR SG+Y KG +K R L L+ N++ Sbjct: 288 S-SCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFS 346 Query: 453 GQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMN 512 R +Y APTD+ L +K +++ +++ ++ LC +D +T W+ R+ KYG LY N Sbjct: 347 LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN 406 Query: 513 YQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPA 564 Y+ +R S S+ ++S S +S + S + + ++ Q A Sbjct: 407 YRIPQQRKA----LLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSA 454 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 150 bits (380), Expect = 6e-36 Identities = 188/668 (28%), Positives = 244/668 (36%), Gaps = 99/668 (14%) Query: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594 SG + P ++ S G S T G + + + S E RG E ++ Sbjct: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 155 Query: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---------- 644 + + R TS P +P P + A+ LP P P P PP P Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215 Query: 645 --PPPPLPSQSAPSAGSAAPMFVKYS---TITRLQNASQHSGALFKPPTPPVMQSQSVKP 699 P ++ PSAG S + T L + ++ + P P SQ KP Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KP 274 Query: 700 ---QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP-PLKIHQVQHI 755 Q L PP V PP P P S+ P+P A Q APP P H Sbjct: 275 KGLQALRPPQ-VTPPRKDAAPALGPLSSSPLATPSPSAAL--QSQAPPTLPATPHSSSLT 331 Query: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQA-----APP-----T 805 Q+A P P PP AP Q P P T P+ +T +P + +PP T Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391 Query: 806 PTPPVPPAKKQPAFPASYIPP-SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ 864 P P PPA P A PP SPP P+ P P P + +P SP PS Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPS--PP 447 Query: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPE 922 + + F PP +PP S A Q+PP++ A P P S P P P PPP+ Sbjct: 448 VQAPFSPPASPPVSPS-------ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 923 SSLVFPPP---PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979 + PPP PP + PPP PP A TP P SP P P S Sbjct: 501 A----PPPLAAPPLQLAKPPPQAPP-ALATPPLQALP--------SPPASFPGQAPFSPS 547 Query: 980 SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLP 1038 + S P P+ P V + PP+ SP TL P PP PG ++SG L Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP---TLQAPRRPPTPGPDTSVSGPRLT 604 Query: 1039 GVLQQG---------CVSAKAPVLSGRGK------DSVVEFPSPPSDSDFPPPPPETELP 1083 L G + P L+G + + + S P PPP+ EL Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664 Query: 1084 LPPIEIPAVFSGNTSPKVAV--VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQ 1141 PA +S +P +A P W PP T P D L +E Sbjct: 665 ACH---PAAWSRGPAPPLAFRGAPGAPLPW--------PPATGPGSADG--LCTIYETEG 711 Query: 1142 PTMATVVP 1149 P AT P Sbjct: 712 PESATPAP 719 Score = 117 bits (293), Expect = 7e-26 Identities = 166/666 (24%), Positives = 239/666 (35%), Gaps = 94/666 (14%) Query: 621 ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS 680 A P+ P P PP P PPPP P + +AG+ + A Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-------PLAERAGGIG 66 Query: 681 GALFKPPTPPVMQSQSV-----KPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKP 730 GA P ++S P P +G PP P P +PG A +P Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 731 APCAPSLPQFSA----------PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780 P + SA P + PTP P P A A + Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186 Query: 781 PLVTIPAPTS-----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835 + PAP++ T+ V+ A+ + T P P A+++P+ P+ + Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246 Query: 836 PPPTLPKQQSFCAK-PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894 P + P + A+ P +P P K + + PP TPP ++ P P + +P + Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLA 305 Query: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954 P+ A + Q P P P SSL P P+ P P PP+ P Sbjct: 306 TPSPSAALQSQ------APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359 Query: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSS---SGAEHPEPKRPSVDSLVSKFTPPAESG 1011 +P + T+S G PT Q S S S P P+ P +L PP+ Sbjct: 360 TP--PSQATTSLGS----PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413 Query: 1012 SPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDS 1071 SP P A P P N V+L +AP PSPP + Sbjct: 414 SPPLS----PLATPSPQAPNALAVHL----------LQAPFSPP---------PSPPVQA 450 Query: 1072 DFPPP--PPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND 1129 F PP PP + PP + P + +P + V P P MS PPP P Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLA---APPLQ-VPPSPPASPPMSPSATPPPQAPPPLA 506 Query: 1130 STRLTQAEISEQ--PTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSR 1187 + L A+ Q P +AT Q SP +S Q F + + L++ Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM--------SPLATP 558 Query: 1188 MSRAEPTATMDDMALPPPP---PELLSDQQKAGYG-GSHISG-YATLRRGP-PPAPPKRD 1241 +A P + +PP P P L + ++ G + +SG TL P PP PP R Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618 Query: 1242 QNTKLS 1247 ++ LS Sbjct: 619 PSSTLS 624 Score = 117 bits (293), Expect = 7e-26 Identities = 115/392 (29%), Positives = 138/392 (35%), Gaps = 68/392 (17%) Query: 624 PSPPLPP---PPPPPPP----PP---PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673 PSPPL P PPP PP PP PP PP PPL + PS + + V Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441 Query: 674 QNASQHSGALFKPP-TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP 732 S A F PP +PPV S S P PP+ PP PP PP P P Sbjct: 442 PPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499 Query: 733 CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP--APTS 790 AP P +APP Q+A P P PP + P P QA P P + P AP S Sbjct: 500 QAP--PPLAAPP-----------LQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFS 545 Query: 791 TKTVAPVVTQAAPPTPTPPV--------PPAKKQPAFPASYIPPSPPTP----------- 831 P+ A PP PPV PP+ PA P P PPTP Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRL 603 Query: 832 -----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMES 880 P P PPP+ + S S +++ P PP E Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663 Query: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940 P + P P A + P P+P P P L P A P Sbjct: 664 AACHPAAWSRGPAPPLAFRGAP-----GAPLPWPPATGPGSADGLCTIYETEGPESATPA 718 Query: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972 P P+P SG GK + + + P Sbjct: 719 PGALDPGPSPGTSG--GKAAAGAGAGASSRSP 748 Score = 51.6 bits (122), Expect = 5e-06 Identities = 95/414 (22%), Positives = 146/414 (35%), Gaps = 66/414 (15%) Query: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP----------AMESQPLKPVPANVA 891 K ++ A P+ +P + S PPPP P A+ +PL + Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP---TASP 948 + P ++ P+ P+ S P P +S PP+ +P P P + + Sbjct: 67 GATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 949 TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS-SIKSSSGAEHPEPKRPSV---------- 997 P G G + S + K P+R++ S + P P PS Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 998 -------DSLVSKFTPPAE-------SGSPSKETLPPPAAPPKPGKLNLSGVNLPG--VL 1041 + ++ PP E S S T P PAA +P G+ P L Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--GGGLQRPASRSL 242 Query: 1042 QQGCVSAKAPVLSG---RGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTS 1098 +P SG RG PS P P P PA+ ++S Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302 Query: 1099 PKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSS 1158 P + P P +++ PPT P S+ LT +AT +P P SP + Sbjct: 303 P---LATPSP----SAALQSQAPPTLPATPHSSSLT-------CQLATPLPLAPPSPSAP 348 Query: 1159 LSVQPGFLADLNRTLQRKSITRHGSLSSRMSRA-EPTATMDDMALPPP--PPEL 1209 S+Q L T ++ T GS + + + + P+ + +A PPP PP L Sbjct: 349 PSLQT--LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 144 bits (363), Expect = 5e-34 Identities = 160/546 (29%), Positives = 214/546 (39%), Gaps = 110/546 (20%) Query: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590 SS +K SSS S S+ S+ SDS S+T+ A ++ K+G E Sbjct: 692 SSKMKGFSSSES---ESSSESSSSDSEDSETEMA-------------PKSKKKGHPGREQ 735 Query: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP-----PPPPPP 645 K + + + +P P+ PP PP PPPPPPP PPPPPP Sbjct: 736 KKHH----HHHHQQMQQAPAPVPQ----------QPPPPPQQPPPPPPPQQQQQPPPPPP 781 Query: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP---TPPVMQSQSVKPQIL 702 PP +P Q+AP+ S+ P F+ + + L+ Q G++F P T P++ PQ Sbjct: 782 PPSMPQQAAPAMKSSPPPFIA-TQVPVLE--PQLPGSVFDPIGHFTQPILH----LPQPE 834 Query: 703 VPPNGVVPPPPPPPP---------PPTPGSAMAQ--LKPAPCAPSLPQFSAPPPPLKIHQ 751 +PP+ PP PP PP +A+ Q +P+ A +LP A PP + Sbjct: 835 LPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPAL 894 Query: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPP----------KPLVTIPAPTSTKTVAPVVTQA 801 Q PP PP + P APP + L + PT V +Q Sbjct: 895 TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP 954 Query: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSV 861 PP P PP P ++Q P PP PP P PP P+QQ +PPP P+ P Sbjct: 955 PPPLPPPPHPSVQQQ-----LQQQPPPPPPPQPQPP---PQQQH---QPPPRPVHLQPMQ 1003 Query: 862 VKQIASQFPP-----PPTPPAMES----QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912 Q PP PP PP + QP KP SP K+ P P Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAP 1063 Query: 913 SPDFPPPPPES---SLVFPPPPPSPV--------PAPPPPPPPTASPTPDKSGSPGKKTS 961 SP P S SL PP V A P P +K SP ++ Sbjct: 1064 SPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE 1123 Query: 962 KTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020 S +PP P+ SIK+ + PE K V V + P ++ PP Sbjct: 1124 PFSPSLRPEPPKHPE---SIKAPVHLPQRPEMKPVDVGRPVIR---------PPEQNAPP 1171 Query: 1021 PAAPPK 1026 P AP K Sbjct: 1172 PGAPDK 1177 Score = 100 bits (250), Expect = 7e-21 Identities = 130/507 (25%), Positives = 181/507 (35%), Gaps = 82/507 (16%) Query: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809 H Q + Q P P PPP PPQ PP P P P Q PP P PP Sbjct: 741 HHHQQMQQAPAPVPQQPPP-----PPQQPPPP----PPPQQQ--------QQPPPPPPPP 783 Query: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQF 869 P + PA +S PP VPV P LP S P+ + I Sbjct: 784 SMPQQAAPAMKSS--PPPFIATQVPVLEPQLPG----------SVFDPIGHFTQPIL-HL 830 Query: 870 PPPPTPPAMESQPLKPVPANV---APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926 P P PP + P P ++ A SPPA+ QPS + PP P V Sbjct: 831 PQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAV 890 Query: 927 FPPPPPSPV-PAPPPPPPPTASPTPDKSGSPGKKTSKTS---SPGGKKPPPTPQRNS-SI 981 P +P+ P PP PP ++ +P + + K PPTP S + Sbjct: 891 SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKV 950 Query: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA--PPKPGKLNLSGVNLPG 1039 +S P P PSV + + PP P + PPP P P ++L + Sbjct: 951 QSQPPPPLPPPPHPSVQQQLQQQPPP----PPPPQPQPPPQQQHQPPPRPVHLQPMQFST 1006 Query: 1040 VLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP-PIEIPAVFSGNTS 1098 +QQ P PP P PPP + P P P + V + S Sbjct: 1007 HIQQ---------------------PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045 Query: 1099 PKVAVVNPQPQQWSKMSVKKAPPPT---RPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 P+ +P +S +++AP P P+ + LT + P V P+ Sbjct: 1046 PRHHKSDP----YSTGHLREAPSPLMIHSPQMSQFQSLTH----QSPPQQNVQPKKQELR 1097 Query: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215 +S+ VQP L + I R S + R EP + + P P+ + + Sbjct: 1098 AASV-VQPQPLVVVKEEKIHSPIIRSEPFSPSL-RPEPPKHPESIKAPVHLPQ-RPEMKP 1154 Query: 1216 AGYGGSHISGYATLRRGPPPAPPKRDQ 1242 G I + PPP P +D+ Sbjct: 1155 VDVGRPVIR--PPEQNAPPPGAPDKDK 1179 Score = 64.3 bits (155), Expect = 7e-10 Identities = 151/776 (19%), Positives = 237/776 (30%), Gaps = 145/776 (18%) Query: 585 TQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP 644 TQ + + +++ P+ ++ P L Q TP P PL PPP PP P PPP P Sbjct: 208 TQTPQPNPPPVQATPHPFPAVTPDLIVQ----TPVMTVVPPQPLQTPPPVPPQPQPPPAP 263 Query: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS-GALFKPPTPPV--------MQSQ 695 P P+ S A + P+ K + + + + +PP+ P + + Sbjct: 264 APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE 323 Query: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755 S +P + PP VP P P QLK C+ L + A +H Sbjct: 324 SSRP--VKPPKKDVPDSQQHPAPEKSSKVSEQLK--CCSGILKEMFAK---------KHA 370 Query: 756 TQVAP---PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA---------- 802 P P + P + TI + + A Sbjct: 371 AYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430 Query: 803 ---PPTPTPPVPPAKKQPAFPASY--IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857 PP K Q F + +P P P V V P +P A P S S Sbjct: 431 KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS 490 Query: 858 VPSV----------------VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901 S + ++ Q A SQP + P K K Sbjct: 491 DSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550 Query: 902 PKWQPSSIPVPSPDFPPPPPE-----SSLVFPPPPPSPVPAPPPPPPPTASPTPDK---- 952 K + PPP+ +S P P PPP S DK Sbjct: 551 HKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPM 610 Query: 953 ------------SGSPGKK-------------TSKTSSPGGKK------PPPTPQRNSSI 981 + PG+K + K S+P + P T + Sbjct: 611 SYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERY 670 Query: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041 +S + +P+ VD + S S S+ + ++ + + ++ P Sbjct: 671 VTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMA----PKSK 726 Query: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSP-------PSDSDFPPPPPETELPLPPIEIPAVFS 1094 ++G + + + P+P P PPPPP+ + PP P Sbjct: 727 KKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP 786 Query: 1095 GNTSP------------KVAVVNPQ------------PQQWSKMSVKKAPP--PTRPKRN 1128 +P +V V+ PQ Q + + PP P P+ + Sbjct: 787 QQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHS 846 Query: 1129 DSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRM 1188 L Q + P + +PQ P+ P + + P A ++T+ L Sbjct: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA--RPPAVSPALTQTPLLPQPP 904 Query: 1189 SRAEPTATMDDMALPPPPPELLSDQ------QKAGYGGSHISGYATLRRGPPPAPP 1238 P ++D P PP + Q QK + + PPP PP Sbjct: 905 MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP 960 Score = 59.3 bits (142), Expect = 2e-08 Identities = 50/194 (25%), Positives = 65/194 (33%), Gaps = 25/194 (12%) Query: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752 ++ + KP + PN PP P P Q P P P P Sbjct: 185 ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP------- 237 Query: 753 QHITQVAPPTP--PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810 + V PP P PPP P P PP A PAP ++ P++ P T Sbjct: 238 --VMTVVPPQPLQTPPPVPPQPQPPPA--------PAPQPVQSHPPIIAATPQPVKTKKG 287 Query: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870 K P + P P P P T Q+ ++P P VP SQ Sbjct: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD------SQQH 341 Query: 871 PPPTPPAMESQPLK 884 P P + S+ LK Sbjct: 342 PAPEKSSKVSEQLK 355 Score = 58.5 bits (140), Expect = 4e-08 Identities = 46/151 (30%), Positives = 58/151 (38%), Gaps = 6/151 (3%) Query: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ-PSSIPVPSPDFPPPPPESSLVFPPPPP 932 TPP ++ P P P PAV Q P VP PPP PPP P Sbjct: 204 TPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263 Query: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG----KKPPPTPQRNSSIKSSSGAE 988 +P P PP A+P P K+ K+ + T++P +PP P + K E Sbjct: 264 APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE 323 Query: 989 HPEP-KRPSVDSLVSKFTPPAESGSPSKETL 1018 P K P D S+ P E S E L Sbjct: 324 SSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354 Score = 52.4 bits (124), Expect = 3e-06 Identities = 55/192 (28%), Positives = 69/192 (35%), Gaps = 48/192 (25%) Query: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808 + V + TQ + P P P P P P QA P P PA T V V PP P Sbjct: 193 VSTVPNTTQASTP-PQTQTPQPNPPPVQATPHPF---PAVTPDLIVQTPVMTVVPPQPLQ 248 Query: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868 PP +PP P PP P P PV S IA+ Sbjct: 249 TPPP-----------VPPQPQPPPAPAP-------------------QPVQSHPPIIAAT 278 Query: 869 FPPPPTPPAMESQPLKPVPANVAP-QSPPAVKAKPKW------QPSSIPV--PSPDFP-- 917 P T ++ + P + P PP++ +PK + SS PV P D P Sbjct: 279 PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS 338 Query: 918 ---PPPPESSLV 926 P P +SS V Sbjct: 339 QQHPAPEKSSKV 350 Score = 52.0 bits (123), Expect = 4e-06 Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 11/168 (6%) Query: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAK 849 T T P V+ P T PP Q P PP TP P P P L Q Sbjct: 186 TGTAKPGVS-TVPNTTQASTPP---QTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241 Query: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP--LKPVPANVAPQSPPAVKAKPKWQPS 907 PP PL P V Q Q PP P P ++S P + P V + KA + Sbjct: 242 VPPQPLQTPPPVPPQ--PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299 Query: 908 SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS--PTPDKS 953 P+ P PP P+++ + S PP P + P P+KS Sbjct: 300 IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347 Score = 47.8 bits (112), Expect = 7e-05 Identities = 51/201 (25%), Positives = 68/201 (33%), Gaps = 50/201 (24%) Query: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG 681 ++P P PP P P P P Q+ P Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP------------------------ 224 Query: 682 ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP---PPPTPGSAMAQLKPAPCAPSLP 738 F TP ++ V +VPP + PPP PP PPP P P P P Sbjct: 225 --FPAVTPDLIVQTPV--MTVVPPQPLQTPPPVPPQPQPPPAPA-------PQPVQSHPP 273 Query: 739 QFSAPPPPLKIHQ-VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPV 797 +A P P+K + V+ PT P P LPP+ PK S++ V P Sbjct: 274 IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE--PKTTKLGQRRESSRPVKP- 330 Query: 798 VTQAAPPTPTPPVPPAKKQPA 818 P VP +++ PA Sbjct: 331 --------PKKDVPDSQQHPA 343 Score = 37.0 bits (84), Expect = 0.12 Identities = 42/183 (22%), Positives = 65/183 (35%), Gaps = 33/183 (18%) Query: 973 PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNL 1032 PT + I + G + + VS ++ +P + P P PP + Sbjct: 165 PTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP 224 Query: 1033 SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPP-PPETELPLPPIEIPA 1091 P ++ Q PV++ VV PP PPP PP+ + P P P Sbjct: 225 FPAVTPDLIVQ------TPVMT------VV----PPQPLQTPPPVPPQPQPPPAPAPQPV 268 Query: 1092 VFSGNTSPKVAVVNPQPQQWSKMSVKKA------------PPPTRPKRNDSTRLTQAEIS 1139 + P + PQP + K +KA PP+ P +T+L Q S Sbjct: 269 ----QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRES 324 Query: 1140 EQP 1142 +P Sbjct: 325 SRP 327 Score = 37.0 bits (84), Expect = 0.12 Identities = 36/147 (24%), Positives = 51/147 (34%), Gaps = 34/147 (23%) Query: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP-----PPSPVPAPPP 940 VP +PP + QP+ PV + P P L+ P PP P+ PPP Sbjct: 196 VPNTTQASTPPQTQTP---QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP 252 Query: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000 P P P + +P P PP +K+ G KR + + Sbjct: 253 VP---PQPQPPPAPAP--------QPVQSHPPIIAATPQPVKTKKGV-----KRKADTTT 296 Query: 1001 VSKFTPPAESGSPSKETLPPPAAPPKP 1027 + P E PP+ PP+P Sbjct: 297 PTTIDPIHE----------PPSLPPEP 313 Score = 33.9 bits (76), Expect = 1.00 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 30/161 (18%) Query: 952 KSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS------------VDS 999 K G+K + T+ PG P T Q ++ ++ + +P P + + V + Sbjct: 177 KGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236 Query: 1000 LVSKFTPPAESGSP---SKETLPPPAAPPKPGKLN---LSGVNLPGVLQQGCVSAKAPVL 1053 V PP +P + PPPA P+P + + ++ P ++G V KA Sbjct: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG-VKRKADTT 295 Query: 1054 SGRGKDSVVEFPSPP-----------SDSDFPPPPPETELP 1083 + D + E PS P +S P PP+ ++P Sbjct: 296 TPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336 >gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] Length = 532 Score = 143 bits (360), Expect = 1e-33 Identities = 84/284 (29%), Positives = 143/284 (50%), Gaps = 5/284 (1%) Query: 272 VIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHE 331 V++V+ D + +++ V T R V + L+ ++H W LVE L +ER EDHE Sbjct: 103 VVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHE 162 Query: 332 NLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCG 391 ++VE W ++ +F + KY LFK+ + L +K + D + + E+ Sbjct: 163 SVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQN 222 Query: 392 --SSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVN 449 ++ + PEI+G L L+ G+K WK+ + LR SG+YY KG +K R L ++ N Sbjct: 223 FLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESN 282 Query: 450 VYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQL 509 VY R Y PTD+ +K +++ + ++ C +D ++ W+ R+ KYG QL Sbjct: 283 VYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQL 342 Query: 510 YMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQ 553 Y NYQ+A R + L S ++S S ++ + S H+ + Sbjct: 343 YKNYQQAQSRHLHP---SCLGSPPLRSASDNTLVAMDFSGHAGR 383 Score = 31.2 bits (69), Expect = 6.5 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 9/69 (13%) Query: 870 PPPPTPPAMESQPLKPVPANVAPQSP---PAVKAKPKWQP------SSIPVPSPDFPPPP 920 P P TPP P P+P V P P K + + SIP P P+ PP Sbjct: 19 PAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPP 78 Query: 921 PESSLVFPP 929 +S ++ P Sbjct: 79 SQSPILGGP 87 >gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] Length = 532 Score = 143 bits (360), Expect = 1e-33 Identities = 84/284 (29%), Positives = 143/284 (50%), Gaps = 5/284 (1%) Query: 272 VIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHE 331 V++V+ D + +++ V T R V + L+ ++H W LVE L +ER EDHE Sbjct: 103 VVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHE 162 Query: 332 NLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCG 391 ++VE W ++ +F + KY LFK+ + L +K + D + + E+ Sbjct: 163 SVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQN 222 Query: 392 --SSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVN 449 ++ + PEI+G L L+ G+K WK+ + LR SG+YY KG +K R L ++ N Sbjct: 223 FLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESN 282 Query: 450 VYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQL 509 VY R Y PTD+ +K +++ + ++ C +D ++ W+ R+ KYG QL Sbjct: 283 VYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQL 342 Query: 510 YMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQ 553 Y NYQ+A R + L S ++S S ++ + S H+ + Sbjct: 343 YKNYQQAQSRHLHP---SCLGSPPLRSASDNTLVAMDFSGHAGR 383 Score = 31.2 bits (69), Expect = 6.5 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 9/69 (13%) Query: 870 PPPPTPPAMESQPLKPVPANVAPQSP---PAVKAKPKWQP------SSIPVPSPDFPPPP 920 P P TPP P P+P V P P K + + SIP P P+ PP Sbjct: 19 PAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPP 78 Query: 921 PESSLVFPP 929 +S ++ P Sbjct: 79 SQSPILGGP 87 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 142 bits (358), Expect = 2e-33 Identities = 175/645 (27%), Positives = 234/645 (36%), Gaps = 83/645 (12%) Query: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594 SG + P ++ S G S T G + + + S E RG E ++ Sbjct: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 146 Query: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA 654 + + R TS P +P P + A+ LP P P P PP P + S S Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS-VSSASE 205 Query: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV--KPQILVPPNGVVPPP 712 S +P + G L +P + + S + P P P Sbjct: 206 HSTTEPSPA---------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 Query: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA- 771 P P P P A L+P P + PL + + APP+P PP + Sbjct: 257 PAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315 Query: 772 PLPPQAPPKPLVT-IPAPT--STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP-S 827 P PP PP T + +PT +T + P + TP P PPA P A PP S Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375 Query: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887 PP P+ P P P + +P SP PS + + F PP +PP S Sbjct: 376 PPLSPLATPSPQAP--NALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPS------- 424 Query: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP---PPSPVPAPPPPP 942 A Q+PP++ A P P S P P P PPP++ PPP PP + PPP Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAAPPLQLAKPPPQA 480 Query: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002 PP A TP P SP P P S+ S P P+ P V + Sbjct: 481 PP-ALATPPLQALP--------SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531 Query: 1003 KFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQQG---------CVSAKAPV 1052 PP+ SP TL P PP PG ++SG L L G + P Sbjct: 532 LQVPPSPPASP---TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588 Query: 1053 LSGRGK------DSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV--V 1104 L+G + + + S P PPP+ EL PA +S +P +A Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH---PAAWSRGPAPPLAFRGA 645 Query: 1105 NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP 1149 P W PP T P D L +E P AT P Sbjct: 646 PGAPLPW--------PPATGPGSADG--LCTIYETEGPESATPAP 680 Score = 120 bits (302), Expect = 6e-27 Identities = 137/501 (27%), Positives = 170/501 (33%), Gaps = 91/501 (18%) Query: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590 SS +SG S+ P + ++ S G+ +P V+ +A L S Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-------VTPPRKDAAPALGPLSSS 293 Query: 591 SKARMESMNRPYTSLVPPLS--PQPKIVTPYTASQ--------------PSPPLPP---P 631 A P S P L P P P A+ PSPPL P P Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 Query: 632 PPPPPP----PP---PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684 PP PP PP PP PP PPL + PS + + V S A F Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413 Query: 685 KPP-TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP 743 PP +PPV S S P PP+ PP PP PP P P AP P +AP Sbjct: 414 SPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--PPLAAP 469 Query: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP--APTSTKTVAPVVTQA 801 P Q+A P P PP + P P QA P P + P AP S P+ A Sbjct: 470 P-----------LQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLA 517 Query: 802 APPTPTPPV--------PPAKKQPAFPASYIPPSPPTP----------------PVPVPP 837 PP PPV PP+ PA P P PPTP P P PP Sbjct: 518 TPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 Query: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMESQPLKPVPANVA 891 P+ + S S +++ P PP E P + Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635 Query: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPD 951 P P A + P P+P P P L P A P P P+P Sbjct: 636 PAPPLAFRGAP-----GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690 Query: 952 KSGSPGKKTSKTSSPGGKKPP 972 SG GK + + + P Sbjct: 691 TSG--GKAAAGAGAGASSRSP 709 Score = 120 bits (300), Expect = 1e-26 Identities = 164/671 (24%), Positives = 230/671 (34%), Gaps = 113/671 (16%) Query: 621 ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS 680 A P+ P P PP P PPPP P + +AG+ + A Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-------PLAERAGGIG 66 Query: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKPAPCAP 735 GA P +++ +P P +G PP P P +PG A +P P Sbjct: 67 GATIPESAPRAGPTRTSRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122 Query: 736 SLPQFSA----------PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI 785 + SA P + PTP P P A A + + Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 Query: 786 PAPTS-----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840 PAP++ T+ V+ A+ + T P P A+++P+ P+ + P + Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 Query: 841 PKQQSFCAK-PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPANVAPQSPPAV 898 P + A+ P +P P K + + PP TPP ++ P L P+ ++ P+ Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 Query: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLV-----------FPPPPPSPVPAPPPPPPPTAS 947 P PS +PSP PP ++ + P PP SP+ PPP PP A Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP-AL 361 Query: 948 PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007 P P S SP P P N+ A P P V + F+PP Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQ---APFSPP 416 Query: 1008 AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067 A S S PP APP L P SA P + +P Sbjct: 417 A-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP------PQAPPPLAAP 469 Query: 1068 PSDSDFPPPPPETELPLPPIEI----PAVFSGNT--SPKVAVVNPQPQQWSKMSVKKAPP 1121 P PPP L PP++ PA F G SP ++ MS PP Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL---------PMSPLATPP 520 Query: 1122 PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRH 1181 P P P +A + QVP SP +S ++Q + R Sbjct: 521 PQAP----------------PVLAAPLLQVPPSPPASPTLQ--------------APRRP 550 Query: 1182 GSLSSRMSRAEPTATMDDMALPPPPP-----ELLSDQQKAGYGGS------HISGYATLR 1230 + S + P T+ PPPPP LS AG+ S + GY + Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 610 Query: 1231 RGPPPAPPKRD 1241 G A P D Sbjct: 611 EGGAAASPPPD 621 Score = 61.6 bits (148), Expect = 4e-09 Identities = 107/457 (23%), Positives = 148/457 (32%), Gaps = 107/457 (23%) Query: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM----------------------- 878 K ++ A P+ +P + S PPPP PA Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 Query: 879 -----ESQP-LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP------DFPPP------- 919 ES P P + P S +A P S PV SP P P Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126 Query: 920 ---------------PPESSL-------VFPPPPPSPVPAPP------------PPPPPT 945 P S+L P P +P PA P P P+ Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186 Query: 946 ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005 A P P G P K S S +P P +R + S+G P S+ S + + Sbjct: 187 ARPRPPTEG-PRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSSSATPLS 241 Query: 1006 PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP 1065 PA SG ++ T PA P +P L + P V AP L G S + P Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR--KDAAPAL-GPLSSSPLATP 298 Query: 1066 SPPSDSDFPPPPPETELPLPPIEIP-------------AVFSGNTSPKVA-VVNPQPQQW 1111 SP + PP LP PP P A S SP ++ + P PQ Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358 Query: 1112 SKMSVKK-APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLN 1170 +++ PP+ P + L +A + Q P SP S VQ F + Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418 Query: 1171 RTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207 + ++ S+A P+ + +PP PP Sbjct: 419 PPVSPS--------ATPPSQAPPSLAAPPLQVPPSPP 447 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 141 bits (355), Expect = 4e-33 Identities = 164/591 (27%), Positives = 229/591 (38%), Gaps = 129/591 (21%) Query: 612 QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTIT 671 +P++ P P P P P PPP P PPP S P A + Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA---------S 477 Query: 672 RLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA 731 L A S L + P P PP P PP S + L+ + Sbjct: 478 PLPEALHLSRPLEESPLSP-------------------PPEESPLSPPPESSPFSPLEES 518 Query: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPP---TPPPPPPIPAPLPPQAPPKPLVTIPAP 788 P +P P+ S P P L+ T ++PP +P PP +PL P PP+ L T P P Sbjct: 519 PLSP--PEESPPSPALE-------TPLSPPPEASPLSPPFEESPLSP--PPEELPTSPPP 567 Query: 789 TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS-----PPTPPVPVPPPTLPKQ 843 +++ + PP +P PP ++ P P PP PP P+ PP Sbjct: 568 EASRL-------SPPPEESPMSPPPEESPMSP----PPEASRLFPPFEESPLSPP----- 611 Query: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903 P SPLSP P AS+ PPP E P+ P P +P SPP ++ Sbjct: 612 ------PEESPLSPPPE-----ASRLSPPP-----EDSPMSP-PPEESPMSPPPEVSR-- 652 Query: 904 WQPSSIPVPSPDFPP-------PPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956 S +PV S PP PPPE S PPP S + +PPP PT+ P D SP Sbjct: 653 --LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL-SPPPEDSPTSPPPEDSPASP 709 Query: 957 GKKTSKTSSPGGKKP-PPTPQRNSSIKSSSGAE-HPEPKRPSVDSLVSK--FTPPAES-- 1010 + S S P + P P P+ S G P P+ P + + +P AE Sbjct: 710 PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH 769 Query: 1011 -----------GSPSKETLPP----PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG 1055 P + L P P P+P +L+LS L + P LS Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP---VPEEPCLSP 826 Query: 1056 RGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW-SKM 1114 + ++S + SP S+ P PE P +E P + SP+ +P Q + Sbjct: 827 QPEESHL---SPQSEEPCLSPRPEESHLSPELEKPPL-----SPRPEKPPEEPGQCPAPE 878 Query: 1115 SVKKAPPPTRPKRNDSTRLTQAEISE--QPTMATVVPQVPTSPKSSLSVQP 1163 + PPP P S L + +SE +P ++ + ++P SP S+ P Sbjct: 879 ELPLFPPPGEPSL--SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927 Score = 134 bits (336), Expect = 7e-31 Identities = 154/570 (27%), Positives = 213/570 (37%), Gaps = 95/570 (16%) Query: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPP------ 640 LEES + E + P +L PLSP P+ + SP PPP P PPP Sbjct: 515 LEESPLSPPEE-SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573 Query: 641 PPP------PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694 PPP PPP P P A P F L PP + Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPF--------------EESPLSPPPEESPLSP 619 Query: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPPLK 748 ++ PP PPP P +P +++L P P P S PP Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP 679 Query: 749 IHQVQHITQVAPP---TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805 ++++PP +P PPP +P P P L+++P S P Q P + Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASP-PPEDSLMSLPLEESPLLPLPEEPQLCPRS 738 Query: 806 PTPPVPPAKKQPAF-PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV---PSV 861 P + P ++P P P P P P P++ CA P LSP P + Sbjct: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ-PEEPCLCAVPEEPHLSPQAEGPHL 797 Query: 862 VKQ-----IASQFPPPPTPPAMESQPLKPVP--ANVAPQS-PPAVKAKPKWQPSSIPV-- 911 Q ++ Q P P E L P P ++++PQS P + +P+ S + Sbjct: 798 SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857 Query: 912 ----PSPDFPP------PPPESSLVFPPP------PPSPVPAPPPPPPPTASPTPDK--- 952 P P+ PP P PE +FPPP P PA P P SP P++ Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917 Query: 953 --SGSPGKKTSKTSSPGGKKPPP-----TPQRNSSIKSSSGAEHP-------EPKRP-SV 997 SG P S P PPP T ++ E+P +P+ P + Sbjct: 918 SPSGEP--SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975 Query: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057 L + +PP E+ E +PP PP PG + G P +L + +P+L Sbjct: 976 PILETPISPPPEANCTDPEPVPPMILPPSPG--SPVGPASP-ILMEPLPPQCSPLL---- 1028 Query: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087 + S+V SPPS P P PL PI Sbjct: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058 Score = 131 bits (330), Expect = 4e-30 Identities = 180/688 (26%), Positives = 256/688 (37%), Gaps = 131/688 (19%) Query: 608 PLSPQPKI--VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665 PLSP P+ ++P S P PL P PP PP P PL P A +P F Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL--SPPPEASPLSPPF- 549 Query: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP---PPPPPPTPG 722 S S + PT P ++ + P P + PPP P PPP Sbjct: 550 ---------EESPLSPPPEELPTSPPPEASRLSPP---PEESPMSPPPEESPMSPPPEAS 597 Query: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP---TPPPPPPIPAPLPPQAPP 779 + +P +P + PPP ++++PP +P PPP +P+ P Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPP-------EASRLSPPPEDSPMSPPPEESPMSP---- 646 Query: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV-PPAKKQPAFP---ASYIPP----SPPTP 831 P S + PVV++ +PP P+ PP ++ P P AS + P SP +P Sbjct: 647 ------PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700 Query: 832 PVPVPPPTLPKQQSFCAKP-PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP--A 888 P P + P + S + P SPL P+P Q+ + P P E L P P Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPE-EPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759 Query: 889 NVAPQS-PPAVKAKPKWQPSSIPVP-SPDFPP--------PPPESSLVFP---PPPPSPV 935 +++PQ+ P + +P+ +P VP P P P PE + P P SPV Sbjct: 760 HLSPQAEEPHLSPQPE-EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818 Query: 936 PAPP---PPP----------PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK 982 P P P P P SP P++S + SP +KPP P + + + Sbjct: 819 PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878 Query: 983 SSSGAEHPEPKRPSVDSLVSK--FTPPAESG-SPSKETLP-PPAAPPKPGKLNLSGVNLP 1038 P P PS+ L+ + + P E SP E LP P+ P + LP Sbjct: 879 EL--PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936 Query: 1039 GVLQQGCVSAKAPVLSGRGK---------DSVVEFP----------SPPSDSDFPPPPPE 1079 L +A P LS G+ DS E P SPP +++ P P Sbjct: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996 Query: 1080 TELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRL------ 1133 + LPP P G SP ++ P P Q S + P P S Sbjct: 997 PPMILPP--SPGSPVGPASP--ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052 Query: 1134 -------------TQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITR 1180 +AE+ E T P+ P S+ S P + DL+ + Sbjct: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPA--- 1109 Query: 1181 HGSLSSRMSRAEPTATMDDMALPPPPPE 1208 +L E TA +D + P PE Sbjct: 1110 -PALDDFSGLGEDTAPLDGIDAPGSQPE 1136 Score = 103 bits (256), Expect = 1e-21 Identities = 154/639 (24%), Positives = 220/639 (34%), Gaps = 106/639 (16%) Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660 P S + PL ++ P S SPP P PPP PPP P+ P A Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707 Query: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720 +P L + L P P + +S P + P P P P + Sbjct: 708 SP-----PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762 Query: 721 PGSAMAQLKPAPCAPSL----------PQFSAP---PPPLKIHQVQHITQVAPPTPPPPP 767 P + L P P P L PQ P P P ++H + T+ +P P Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPEE 821 Query: 768 PIPAPLPPQAPPKPLVTIP--APTSTKTVAPVVTQAAPPTPTPPVPP--------AKKQP 817 P +P P ++ P P +P ++ + P +P P PP ++ P Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881 Query: 818 AFPASYIPPSPP--TPPVPVPPPTLPKQQSFCAKPPPSPLSP--VPSVVKQIASQFPPPP 873 FP PP P +P + P + P + P PLSP PS+ Q+ PP P Sbjct: 882 LFP----PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL---MPPDP 934 Query: 874 TPPAMESQPLKPVPANVAP------------------QSPPAVKAKPKWQPSSIPVPSPD 915 PP PL P+ AP P + A P + P P + Sbjct: 935 LPP-----PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989 Query: 916 FPPPPPESSLVFPPPPPSPV-PAPP---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971 P P ++ PP P SPV PA P P PP SP S P + S P P Sbjct: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP-----QNSPPSQCSP 1044 Query: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031 P P S S G + + ++ + P L P A P P + Sbjct: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETE-----KVSEPECPALEPSATSPLPSPMG 1099 Query: 1032 LSGVNLPGVLQQGCVSAKAPVL---SGRGKDSV----VEFPSPPSDSDFPPPPPETELP- 1083 P + AP L SG G+D+ ++ P + P +EL Sbjct: 1100 DLSCPAP---------SPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKG 1150 Query: 1084 ----LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP----PPTRPKR---NDSTR 1132 L P E+ V P+ Q + +AP PPT K N+ + Sbjct: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISN 1210 Query: 1133 LTQAEISEQ-PTMATVVPQVPTSPKSSLSVQPGFLADLN 1170 L+Q + S P ++ SLS++ G D++ Sbjct: 1211 LSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVS 1249 Score = 96.7 bits (239), Expect = 1e-19 Identities = 171/673 (25%), Positives = 232/673 (34%), Gaps = 108/673 (16%) Query: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669 S P + P +P P PP PP P P P PP L + S P AG Sbjct: 2173 SQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG 2232 Query: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729 R Q ++ F P P + + +V P+ G P PPP ++K Sbjct: 2233 TPRHQPSTPDP---FLKPRCPSLDNLAV-PESPGVGGGKASEPLLSPPPFGESRKALEVK 2288 Query: 730 PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA----PPKPLVTI 785 S P + PP + T + P APL P+A P P + + Sbjct: 2289 KEELGASSPSY-GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347 Query: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP--SPPTPPVPVPPPTLPKQ 843 + P QA P+ PP+ P SY P PP P P PPP Sbjct: 2348 ------RPQEPPPAQALAPS-----PPSHPDIFRPGSYTDPYAQPPLTPRPQPPP----P 2392 Query: 844 QSFCAKPPPS-PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP 902 +S CA PP S P P S+ P P + PL P P + P V P Sbjct: 2393 ESCCALPPRSLPSDPF--------SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV--TP 2442 Query: 903 KWQPSSIPVPSP-DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961 ++Q P P PP P+S P +P+ PP P PP + K+GS + Sbjct: 2443 RFQS-----PDPYSRPPSRPQSR-----DPFAPLHKPPRPQPPEVA---FKAGS----LA 2485 Query: 962 KTSSPGGKKP---PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS-----KFTPPAESGSP 1013 TS G P P P K SG + P + V +FT P G P Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP 2545 Query: 1014 S-KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGR---------------G 1057 S K +P P PP G + G PG S V +G G Sbjct: 2546 SLKPPVPQPGLPPPHGINSHFG---PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602 Query: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117 + + PP S PPP P+ LP + SG TSP +P S ++ Sbjct: 2603 ESYGLSPLRPP--SVLPPPAPDGSLPYLS-HGASQRSGITSPVEKREDPGTGMGSSLATA 2659 Query: 1118 KAPPPTRP-----------KRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV-QPGF 1165 + P P K+ RL + I +Q T+ + T+ ++ +V PG Sbjct: 2660 ELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGS 2719 Query: 1166 LADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISG 1225 + + ++R + T D +L PP LS G Sbjct: 2720 WGAEPSSPAFEQLSR--------GQTPFAGTQDKSSLVGLPPSKLSGPI---LGPGSFPS 2768 Query: 1226 YATLRRGPPPAPP 1238 L R PPPA P Sbjct: 2769 DDRLSRPPPPATP 2781 Score = 78.6 bits (192), Expect = 4e-14 Identities = 97/355 (27%), Positives = 138/355 (38%), Gaps = 46/355 (12%) Query: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924 + S P P P E++PL + PQ ++A + +P P PPPE S Sbjct: 401 VTSMQPKEPGPLQCEAKPLGKAGVQLEPQ----LEAPLNEEMPLLPPPEESPLSPPPEES 456 Query: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984 PPP S + PPP ASP P+ SP ++ P +P SS Sbjct: 457 PTSPPPEASRL--SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS---- 510 Query: 985 SGAEHPEPKRPSVDSLVSKFTPPAES-GSPSKET--LPPPAAPPKPGKLNLSGVNLPGVL 1041 P P +S +S PP ES SP+ ET PPP A P S ++ P Sbjct: 511 -------PFSPLEESPLS---PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560 Query: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101 +A LS ++S + SPP + PPPE PP E + + P+ Sbjct: 561 LPTSPPPEASRLSPPPEESPM---SPPPEESPMSPPPEASRLFPPFEESPL---SPPPEE 614 Query: 1102 AVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV 1161 + ++P P+ S++S P P +S E+S + V P +S LS Sbjct: 615 SPLSPPPEA-SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673 Query: 1162 QPGFLADLNRTLQRKSITRHGSLSSRMS---RAEPTA--TMDDMALPPPPPELLS 1211 P +S T +SR+S PT+ D A PPP L+S Sbjct: 674 PP-----------EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMS 717 Score = 70.5 bits (171), Expect = 1e-11 Identities = 121/483 (25%), Positives = 152/483 (31%), Gaps = 135/483 (27%) Query: 709 VPPPP----PPPPPPTPGSAMAQ-LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763 +PP P PPP P + PA + S F PP V P Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAG----------SVPGPDS 2155 Query: 764 PP------PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP---AK 814 P PP +PA +P Q P P T P PT P PP A Sbjct: 2156 PGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGAS 2215 Query: 815 KQPAF--PASYIPPSPPTP------PVPVPPPTLPKQQSFCAKPPPSP-----------L 855 +P P + P TP P P P P + P SP L Sbjct: 2216 SRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV--PESPGVGGGKASEPLL 2273 Query: 856 SPVP--------SVVKQIASQFPPPPTPPAME----------------------SQPLKP 885 SP P V K+ P PP + PL P Sbjct: 2274 SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP 2333 Query: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP---------PPPSPVP 936 + V PQS P + +P+ P P+ P PP +F P PP +P P Sbjct: 2334 RASQVEPQS-PGLGLRPQEPP-----PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP 2387 Query: 937 APPPPP-----PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991 PPPP PP + P+ S P S++SS P P S+ A P Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL---------SAEAFCPS 2438 Query: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP---------GKL---NLSGVNLPG 1039 P P S PP S S++ P PP+P G L +L P Sbjct: 2439 PVTPRFQSPDPYSRPP--SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496 Query: 1040 VLQQGC---VSAKAP------VLSGRGKDSVVEFPSP--------PSDSDFPPPPPETEL 1082 L G + AK P + G + V PSP + PP P+ L Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556 Query: 1083 PLP 1085 P P Sbjct: 2557 PPP 2559 Score = 64.3 bits (155), Expect = 7e-10 Identities = 94/360 (26%), Positives = 123/360 (34%), Gaps = 102/360 (28%) Query: 828 PPTPPVPVPPPTLPKQQSFCAKPP-PSPLSP-VPSVVKQIASQFPPPPTPPAMESQPLKP 885 PP P PP F P P+ LS +K A P P +P + + Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166 Query: 886 VPANVAPQSP----PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 VPA V Q P PA +P+ FP PP PP PSP AP P Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPR------------FPTAPPTY-----PPYPSPTGAPAQP 2209 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001 P AS P +G PG+ + PP TP+ S +P+ PS+D+L Sbjct: 2210 PMLGASSRPG-AGQPGEFHTT--------PPGTPRHQPSTPDP----FLKPRCPSLDNLA 2256 Query: 1002 SKFTPPAESGSPSKETLPPP-----------------AAPPKPGKLNL-------SGVNL 1037 +P G S+ L PP A+ P G NL SG +L Sbjct: 2257 VPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHL 2316 Query: 1038 PGVL-------------QQGCVSAKAPVLSGRGKD---SVVEFPSPPSDSDF-------- 1073 G+ + V ++P L R ++ + PSPPS D Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376 Query: 1074 -----------PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122 PPPPE+ LPP +P S + V PQ S P P Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLP-------SDPFSRVPASPQSQSSSQSPLTPRP 2429 Score = 57.4 bits (137), Expect = 8e-08 Identities = 103/406 (25%), Positives = 136/406 (33%), Gaps = 93/406 (22%) Query: 601 PYTSLVPPLSPQPKIVTP--YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658 P +L P P I P YT PPL P P PPPP PP +S PS Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP------RSLPS-- 2405 Query: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718 +R+ + Q + P TP + +++ P + P P PP Sbjct: 2406 ---------DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456 Query: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPP---LKIHQVQHITQVAPPTPPPPPPIPAPLPP 775 P A L P P PP K + H + A PA LP Sbjct: 2457 PQSRDPFAPLHKPP---------RPQPPEVAFKAGSLAHTSLGA-------GGFPAALPA 2500 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835 + +P+ V T A TP+P + FP + PS PPVP Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSP------MRFTFPQAVGEPS-LKPPVPQ 2553 Query: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895 P PPP ++ S F P PT PQS Sbjct: 2554 P-----------GLPPPHGIN----------SHFGPGPTLG--------------KPQST 2578 Query: 896 PAVKAKPKWQPSSIPV-PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954 A + PS P+ PS ES + P PPS + PPP P + P Sbjct: 2579 NYTVATGNFHPSGSPLGPSSG---STGESYGLSPLRPPSVL---PPPAPDGSLPYLSHGA 2632 Query: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000 S + S +SP K+ P SS+ + AE P + P + L Sbjct: 2633 S---QRSGITSPVEKREDPGTGMGSSLAT---AELPGTQDPGMSGL 2672 Score = 51.2 bits (121), Expect = 6e-06 Identities = 166/788 (21%), Positives = 260/788 (32%), Gaps = 121/788 (15%) Query: 545 ESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTS 604 + Q Q + Q + Q + + ++ QL++ + + + + Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQ 3972 Query: 605 LVPPLSPQPK-IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663 L Q + +++P Q L P P P P P + + P Sbjct: 3973 QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPA 4032 Query: 664 FVKYSTITRLQNASQHSG---ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720 +T + S H G A+ P + VKP + ++ P P P P + Sbjct: 4033 VSSEAT----EGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSS 4088 Query: 721 ---------PGSAMAQLK----------------PAPCAPSLPQFSAPPPPLKIHQVQHI 755 PG Q+ + A S+P A P Q + Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148 Query: 756 TQ--VAPPTPP----------PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803 TQ + P P P PP P P+ P V I PT + A + A Sbjct: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGI-MPTVGQLRAQLQGVLAK 4207 Query: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPV-PVPPPTLPKQQSFCAKPPPSPLSPVPSVV 862 + P ++Q + V PP P Q+ SPL + Sbjct: 4208 NPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQT-------SPLQGLLGCQ 4260 Query: 863 KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE 922 Q+ FP P T P E + A PQ PP + A P S+ PV P P PPP Sbjct: 4261 PQLGG-FPGPQTGPLQE------LGAGPRPQGPPRLPAPPG-ALSTGPVLGPVHPTPPPS 4312 Query: 923 SSLVFPPPPPSPVPAP-----------------PPPPPPTASPTPDKSGSPGKKTSKTSS 965 S P PS +P+P P P PT P P + + + T Sbjct: 4313 SPQ--EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLF 4370 Query: 966 PGGKKP--PP-------TPQRNSSIKSS----SGAEHPEPKRPSVDSLVSKFTPPAESGS 1012 G P PP P+++S + +G PE + S+ + + S Sbjct: 4371 SKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQS 4430 Query: 1013 PSKETLPPP-AAPPKPGKLNLSGVNLPG--VLQQGCVSAKAPVLS-GRGKDSVVEFPSPP 1068 +E P AP L L+G +L Q + AK LS GRG + + + Sbjct: 4431 VKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGH 4490 Query: 1069 SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA--VVNPQPQQWSKMSVKKAPPPTRPK 1126 DS E +L P N A + P+P++ K S + + + Sbjct: 4491 IDSKL--AGLEQKLQGTP--------SNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLR 4540 Query: 1127 RNDSTRLTQAEISEQPTMATVVP--QVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184 + D R ++A + + +++P + + SL G +N Q + G+L Sbjct: 4541 KEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL 4600 Query: 1185 SSRMSRAEPTATMDDMALPPPPPELL------SDQQKAGYGGSHISGYATLRRGPPPAPP 1238 + T ++++ PP PP L S QQK G ++ L P A Sbjct: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNG---VTPSEELGEHPKDAAS 4657 Query: 1239 KRDQNTKL 1246 RD L Sbjct: 4658 ARDSERAL 4665 Score = 47.4 bits (111), Expect = 9e-05 Identities = 95/423 (22%), Positives = 140/423 (33%), Gaps = 73/423 (17%) Query: 593 ARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP--------P 644 +R+ + + +S PL+P+P + S +P P P PP P Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468 Query: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP 704 PP P P + A AGS L + S +G P P + + Sbjct: 2469 PPRPQPPEVAFKAGS-------------LAHTSLGAGGF--PAALPAGPAGEL------- 2506 Query: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764 + VP PP +PG+ P+P + PQ P + PP P Sbjct: 2507 -HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP------------SLKPPVPQ 2553 Query: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824 P P P + P P T+ P ST V T P+ + P+ P+ Sbjct: 2554 PGLPPPHGINSHFGPGP--TLGKPQSTNYT--VATGNFHPSGS-PLGPSSGSTGESYGLS 2608 Query: 825 PPSPPTP-PVPVPPPTLP------KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA 877 P PP+ P P P +LP Q+S P P + +A+ P P Sbjct: 2609 PLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPG 2668 Query: 878 MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937 M + Q + + + Q +++ + + V PP P+ Sbjct: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQRNTL---RQEKETAAAAAGAVGPPGSWGAEPS 2725 Query: 938 PPPPPPPTASPTP-----DKSGSPGKKTSKTSSP---GGKKP-------PPTPQRNSSIK 982 P + TP DKS G SK S P G P PP P SS+ Sbjct: 2726 SPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMD 2785 Query: 983 SSS 985 +S Sbjct: 2786 VNS 2788 Score = 47.0 bits (110), Expect = 1e-04 Identities = 63/242 (26%), Positives = 85/242 (35%), Gaps = 42/242 (17%) Query: 560 DTQPAGHVRSQSIVSSVFSEAWKRGTQLEES-----SKARMESMNRPYTSLVPPLSPQPK 614 DT+P G + + + + W++G E S S A +++N ++ LS K Sbjct: 4754 DTKPYGALGLE-VPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM--K 4810 Query: 615 IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG--------SAAPMFVK 666 I Y P P P P L +S P G + P + Sbjct: 4811 IPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKS-PDTGPDWLKQFDAVLPGYTL 4869 Query: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726 S + L Q S A P PP S + L PPP P PPP+P Sbjct: 4870 KSQLDILSLLKQESPA----PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP----- 4920 Query: 727 QLKPAPCA-PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP-APLPPQAPPKPLVT 784 L P+P + P+ P P PL PP P P+P A P A PKP Sbjct: 4921 -LAPSPASPPTEPLVELPTEPL-------------AEPPVPSPLPLASSPESARPKPRAR 4966 Query: 785 IP 786 P Sbjct: 4967 PP 4968 Score = 46.6 bits (109), Expect = 1e-04 Identities = 89/382 (23%), Positives = 127/382 (33%), Gaps = 62/382 (16%) Query: 630 PPPPPPPPPPPPPPPPPPPL-----PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684 PP PP PP PPP + PS+ A R + + L Sbjct: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678 Query: 685 KPPTPPVMQSQSVK---PQILVPPNGVVPPPPP-------PPPPPTPGSAMAQLKP---A 731 PTPP Q++ V+ + P+ +VP P P P GS + + + Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738 Query: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP---PIPAPLPPQAPPK-------P 781 P P +P+ S P V P T P +P LP K Sbjct: 4739 PVIPLIPRASIP--------------VFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSV 4784 Query: 782 LVTIPAPTSTK------TVAPVVTQAAPPTPTP--PVPPAK--KQPAFPASYIPPSPPTP 831 ++T+ A + VA +++ P + P PA+ +P + P Sbjct: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844 Query: 832 PVPVPPPTLPK-QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890 P T P + F A P L ++ + Q P P PP S NV Sbjct: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDIL-SLLKQESPAPEPPTQHSYTY-----NV 4898 Query: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950 + + A P +PS P P P PP LV P P P P P P +SP Sbjct: 4899 SNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP-- 4956 Query: 951 DKSGSPGKKTSKTSSPGGKKPP 972 +S P + +PP Sbjct: 4957 -ESARPKPRARPPEEGEDSRPP 4977 Score = 40.4 bits (93), Expect = 0.011 Identities = 49/214 (22%), Positives = 75/214 (35%), Gaps = 10/214 (4%) Query: 735 PSLPQFSAPPPPLKIHQVQ-HITQVAPPTPP--PPPPIPAPLPPQAPPKPLVTIPAPTST 791 PS + S PPPP + + Q+ + P P LP Q + L T+ Sbjct: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826 Query: 792 KTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851 ++ ++ P TP P + ++ P + I P P PVP P P Q Sbjct: 2827 TSMRFAMSARFPSTPGPEL--GRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNV 2884 Query: 852 PSPLSPVPSVVK-----QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP 906 L P + Q +P P + + L+ + + P P+ P+ Sbjct: 2885 QKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN 2944 Query: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940 S P P P P LV PP + + P P Sbjct: 2945 SLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978 Score = 39.3 bits (90), Expect = 0.024 Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 12/106 (11%) Query: 610 SPQPKIVTPYTAS-------QPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662 +P+P YT + Q S P P P PPP P P P PP P P+ A P Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944 Query: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV 708 + L AS A KP P + + +P L GV Sbjct: 4945 -----PVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV 4985 Score = 35.4 bits (80), Expect = 0.34 Identities = 84/388 (21%), Positives = 123/388 (31%), Gaps = 67/388 (17%) Query: 634 PPPPPPPPPPPPPPPL---------PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684 PP PP PP PPP + PS+ A R + + L Sbjct: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678 Query: 685 KPPTPPVMQSQSVKPQI---LVPPNGVVPPPPPP-------PPPPTPGSAMAQLKPAPCA 734 PTPP Q++ V+ + P+ +VP P P P GS + + + Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738 Query: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK-PLVTIPAPTSTKT 793 P +P I + + P P P A L + P K P+ T ++ Sbjct: 4739 PVIPL---------------IPRASIPVFPDTKPYGA-LGLEVPGKLPVTTWEKGKGSEV 4782 Query: 794 VAPVVTQAAPPTPTPPVPPAKKQ---PAFPASYIPPSPPTPPVPVPPPTLP-------KQ 843 + AA V A + P SY P +P P K+ Sbjct: 4783 SVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKE 4842 Query: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903 + K P + P +KQ + P ++ L +P P + Sbjct: 4843 KGLEGKSPDTG----PDWLKQFDAVLPGYTLKSQLDILSLLK---QESPAPEPPTQHSYT 4895 Query: 904 WQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963 + S++ V PPP P PPPSP+ P P + PT P T Sbjct: 4896 YNVSNLDVRQLSAPPPEE------PSPPPSPLA-----PSPASPPTEPLVELP---TEPL 4941 Query: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPE 991 + P P P S + A PE Sbjct: 4942 AEPPVPSPLPLASSPESARPKPRARPPE 4969 Score = 33.9 bits (76), Expect = 1.00 Identities = 79/357 (22%), Positives = 115/357 (32%), Gaps = 68/357 (19%) Query: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP----------------SVVKQIASQ 868 PP+PP+ P PPP++ +Q+ P L P S VK + Sbjct: 4619 PPTPPSSLPPTPPPSV-QQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSL-DL 4676 Query: 869 FPPPPTPP-------AMESQPLKPVPANVAPQSPPAV-----------KAKPKWQPSSIP 910 PTPP MES P ++ P S P +W+ Sbjct: 4677 LAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRA 4736 Query: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970 + SP P P S VFP P P + GS S+ K Sbjct: 4737 L-SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAK- 4794 Query: 971 PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK--PG 1028 N + + AE K P+ ++ +P P K P K G Sbjct: 4795 -------NLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEG 4847 Query: 1029 KLNLSGVN----LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP---------- 1074 K +G + VL + ++ +LS ++S P PP+ + Sbjct: 4848 KSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPA--PEPPTQHSYTYNVSNLDVRQ 4905 Query: 1075 --PPPPETELPLPPIEIPAVFSGNTSPKVAVVN---PQPQQWSKMSVKKAPPPTRPK 1126 PPPE P P P+ S T P V + +P S + + +P RPK Sbjct: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962 Score = 31.2 bits (69), Expect = 6.5 Identities = 26/113 (23%), Positives = 48/113 (42%), Gaps = 24/113 (21%) Query: 922 ESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981 +++L PP PPS +P P PPP+ +P ++ + P+ +S Sbjct: 4613 KNNLSNPPTPPSSLP---PTPPPSVQQKMVNGVTPSEELGE-----------HPKDAASA 4658 Query: 982 KSSSGAEHPEPKRPSVDSLVSKFTPP----------AESGSPSKETLPPPAAP 1024 + S A + S+D L + TPP ++ S S +++ P ++P Sbjct: 4659 RDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP 4711 Score = 30.8 bits (68), Expect = 8.5 Identities = 70/328 (21%), Positives = 100/328 (30%), Gaps = 62/328 (18%) Query: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT---------------------ST 791 Q +T+ PP PP P PP + + +V P+ T Sbjct: 4609 QLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDT 4668 Query: 792 KTVAPVVTQAAPPTP----TPPVPPAKKQPA-FPASYIPPSPPTPPVPVPPPTLPKQQSF 846 V + AA PTP T V + + P S +P S P + P P S Sbjct: 4669 SEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSG 4728 Query: 847 CAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP 906 + LSPV ++ P P +++P + V + P K K Sbjct: 4729 RWEQEDRALSPVIPLI-------PRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSE 4781 Query: 907 SSIPVPSPDFPPPPPESSLV-------FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959 S+ + +V P V P P P ++ PG K Sbjct: 4782 VSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGK 4841 Query: 960 ------TSKTSSPGGKK------PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT-- 1005 S + P K P T + I S E P P+ P+ S + Sbjct: 4842 EKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNL 4901 Query: 1006 --------PPAESGSPSKETLPPPAAPP 1025 PP E P P PA+PP Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPP 4929 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 137 bits (346), Expect = 5e-32 Identities = 153/610 (25%), Positives = 211/610 (34%), Gaps = 125/610 (20%) Query: 592 KARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPS 651 K R+ R + VP + P PK V P + P+PP P PPP P P +P Sbjct: 10481 KVRVPEEPRVPPTKVPEVLP-PKEVVP----EKKVPVPPAKKPEAPPPKVPEAPKEVVPE 10535 Query: 652 QSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPP 711 + P P PPT ++ P+ VP +PP Sbjct: 10536 KKVPVPPPKKPEV---------------------PPTKVPEVPKAAVPEKKVPE--AIPP 10572 Query: 712 PPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA 771 P PPP P A ++ P P+ P P+K+ + P PPP P Sbjct: 10573 KPESPPPEVP-EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631 Query: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS---- 827 P + P P V +P V +A PP P P P ++P A PP+ Sbjct: 10632 VPPTKVPEVPKVAVPEKK--------VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE 10683 Query: 828 ---PPTPPVPVPPPTLP----KQQSFCAKPPPSPLSPVPSVVKQIASQFPPP---PTPPA 877 P PP PP P K + AK P P VP V K++ + P P P Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPE 10743 Query: 878 MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP-------------VPSP---DFPPP-- 919 + VP V P+ AV KP+ P+ +P VP P + PPP Sbjct: 10744 APPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803 Query: 920 -------PPESSLVFPPPPPSPVPA---PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK 969 PE + P PVP P PP A P K P KK P Sbjct: 10804 YEEPEEIAPEEEIA--PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEA- 10860 Query: 970 KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGK 1029 PP P+ I+ P P P+ K P K+ P P P K Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKV---PEKPQVPEK 10917 Query: 1030 LNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV---------------------EFPSPP 1068 + L+ + +PG ++ V P K+ VV E P Sbjct: 10918 VELTPLKVPGGEKK--VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKP 10975 Query: 1069 SDSDFPPPPPETELPLP-----------PIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117 + + PPP P E+ +P P ++P + P + + P+P+ + VK Sbjct: 10976 AVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEI-----KPAIPLPAPEPKPKPEAEVK 11030 Query: 1118 K-APPPTRPK 1126 PPP P+ Sbjct: 11031 TIKPPPVEPE 11040 Score = 137 bits (344), Expect = 8e-32 Identities = 148/531 (27%), Positives = 202/531 (38%), Gaps = 76/531 (14%) Query: 626 PPLPPPPPPPPPPPPPPPPPPPP-LPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684 P PP P PP PP +P + P+ P + R+ + Sbjct: 10436 PKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPR------ 10489 Query: 685 KPPT--PPVMQSQSVKPQILVP-PNGVVPPPPPPPPPPTPGSAMAQLK---PAPCAPSLP 738 PPT P V+ + V P+ VP P P PPP P P + + K P P P +P Sbjct: 10490 VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVP 10549 Query: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPP---------IPAPLPPQAPP-KPLVT-IPA 787 P P + + + PP P PPP +P P APP KP VT + Sbjct: 10550 PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV 10609 Query: 788 PTSTKTVAPVVTQAAPPTPTPPVPPAK----KQPAFPASYIPPSPPTPPVPVPPPTLPKQ 843 P + K V P PP P VPP K + A P +P + P P PP + Sbjct: 10610 PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP 10669 Query: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903 + + PP+ VV++ P P PP + P KPVP A PAV AK Sbjct: 10670 EEVALEEPPA------EVVEE-----PEPAAPPQVTVPPKKPVPEKKA----PAVVAK-- 10712 Query: 904 WQPSSIPVPSPDFPP---PPPESSLVFPPPPPSPVPAPPPPPPPTASP-----TPDKSGS 955 +P PV P+ P P + LV P P +P PA P P P P K Sbjct: 10713 -KPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP-PAKVPEVPKEVVPEKKVAVPKKPEV 10770 Query: 956 PGKKTSKT-SSPGGKKPP--PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGS 1012 P K + P ++ P P P+R S E PE P + + + P Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAES-PPPEVYEEPEEIAPE-EEIAPEEEKPVPVAE 10828 Query: 1013 PSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD 1072 + +PPPA P +P K+ + +P + + K P + V+E P Sbjct: 10829 EEEPEVPPPAVPEEPKKI-IPEKKVPVIKKPEAPPPKEP-----EPEKVIE---KPKLKP 10879 Query: 1073 FPPPPPETELPLPPIE--IPAVFSGNTSPKVAV-VNPQPQQWSKMSVKKAP 1120 PPPPP P PP E +F PK V PQ + +++ K P Sbjct: 10880 RPPPPP----PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVP 10926 Score = 130 bits (328), Expect = 6e-30 Identities = 157/610 (25%), Positives = 219/610 (35%), Gaps = 113/610 (18%) Query: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP--PP 643 ++ E+ K + P P P K+ A+ P +P PP P PPP P Sbjct: 10524 KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE 10583 Query: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703 P +P + P+A KP PV ++ P+ +V Sbjct: 10584 APKEVVPEKKVPAAPPK------------------------KPEVTPVKVPEA--PKEVV 10617 Query: 704 PPNGV-VPPPPPPPPPPT-----PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757 P V VPPP P PPT P A+ + K P P+ PPP + + + Sbjct: 10618 PEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPE---SPPPEVFEEPEEVAL 10674 Query: 758 VAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP----PA 813 PP P PA PPQ P +P + VA PP P VP P Sbjct: 10675 EEPPAEVVEEPEPA-APPQVTVPPKKPVPEKKAPAVVAK--KPELPPVKVPEVPKEVVPE 10731 Query: 814 KKQPAFPASYIPPSPPTPP--VP-VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-IASQF 869 KK P +P P PP VP VP +P+++ K P P + VP V K+ + + Sbjct: 10732 KKVPL----VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787 Query: 870 PPPPTPPAMESQP--LKPVPANVAPQS----------PPAVKAKPKWQPSSIP------- 910 P P P ES P + P +AP+ P A + +P+ P ++P Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKII 10847 Query: 911 -------VPSPDFPPP-PPESSLVFPPPPPSPVPAPPPPPPP--------------TASP 948 + P+ PPP PE V P P P PPPP PP Sbjct: 10848 PEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK 10907 Query: 949 TPDKSGSPGK-KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007 P+K P K + + PGG+K ++ PEPK V V + P Sbjct: 10908 VPEKPQVPEKVELTPLKVPGGEK---------KVRKLLPERKPEPKEEVVLKSVLRKRPE 10958 Query: 1008 AESG--SPSK-ETLPPPAAPPKPGKLNLSGVNLPGVLQQG---CVSAKAPVLSGRGKDSV 1061 E P K E + PA P P + V +P V ++ K P + Sbjct: 10959 EEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPA 11018 Query: 1062 VE-FPSPPSDSDFPPPPPETELPLP---PIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117 E P P ++ PPP P P P+ +P V + +P+ K K Sbjct: 11019 PEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPK 11078 Query: 1118 KAPPPTRPKR 1127 K P P +R Sbjct: 11079 KTPSPIEAER 11088 Score = 119 bits (299), Expect = 1e-26 Identities = 149/584 (25%), Positives = 211/584 (36%), Gaps = 102/584 (17%) Query: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPP-PPTPGSAMAQLKPAPCAPSLPQFSAPP 744 PP P + + + P+ PP VVP PP P P + + K P P+ Sbjct: 10439 PPKGPEISEKIIPPK--KPPTKVVPRKEPPAKVPEVPKKIVVEEKVR--VPEEPRV---- 10490 Query: 745 PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP 804 PP K+ +V +V P P PP P P PPK P + K V P + P Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEAP--PPK------VPEAPKEVVP---EKKVP 10539 Query: 805 TPTPPVP--PAKKQPAFPASYIP-----------PSPPTPPVPVPPPTLPKQQSFCAKPP 851 P P P P K P P + +P P P P VP P + ++ A PP Sbjct: 10540 VPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPP 10599 Query: 852 PSP-LSP--VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS 908 P ++P VP K++ + P PP P VP P V K P + Sbjct: 10600 KKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVP------EVPKVAVPEKKVPEA 10653 Query: 909 IPVPSPDFPPP-----PPESSLVFPPPPPSPVPAPPPPPP---PTASPTPDKSGSPGKKT 960 IP P P+ PPP P E +L PP P P PP P P P+K +P Sbjct: 10654 IP-PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK-APAVVA 10711 Query: 961 SKTSSPGGKKP----PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE 1016 K P K P P++ + E P K P V V P + P K Sbjct: 10712 KKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV---VPEKKVAVPKKP 10768 Query: 1017 TLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV--------VEFPSPP 1068 +PP P P K L P V + P + ++ E P P Sbjct: 10769 EVPPAKVPEVPKKPVLE--EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPV 10826 Query: 1069 SDSDFP--PPPPETELP---LPPIEIPAVFSGNTSPKVAVVNPQPQ---QWSKMSVKKAP 1120 ++ + P PPP E P +P ++P + P P+P+ + K+ + P Sbjct: 10827 AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP---KEPEPEKVIEKPKLKPRPPP 10883 Query: 1121 PPTRPKRNDSTR-------LTQAEISEQPTMATVVP----QVPTSPKSSLSVQPGFLADL 1169 PP P + D + + ++ E+P + V +VP K + P + Sbjct: 10884 PPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEP 10943 Query: 1170 NRTLQRKSITRHGSLSSRMSRAEPTATMDDM------ALPPPPP 1207 + KS+ R R EP + A+P PPP Sbjct: 10944 KEEVVLKSVLR-----KRPEEEEPKVEPKKLEKVKKPAVPEPPP 10982 Score = 114 bits (285), Expect = 6e-25 Identities = 130/544 (23%), Positives = 195/544 (35%), Gaps = 104/544 (19%) Query: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP----QAPPKPLVT--IPA 787 A + F P P K ++ ++ PP PP +P PP + P K +V + Sbjct: 10427 AEEVEVFEKPKAPPKGPEISE--KIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRV 10484 Query: 788 PTSTKTVAPVVTQAAPPTPTPP-----VPPAKKQPAFPASYIPPSP----PTPPVPVPPP 838 P + V + PP P VPPAKK P P +P +P P VPVPPP Sbjct: 10485 PEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKK-PEAPPPKVPEAPKEVVPEKKVPVPPP 10543 Query: 839 TLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT--PPAMESQPLKPVPANVAPQSPP 896 P+ K P P + VP K++ PP P PP + P + VP P +PP Sbjct: 10544 KKPEVPP--TKVPEVPKAAVPE--KKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPP 10599 Query: 897 AVKAKPKWQPSSIPVPSPDFPPPP-PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS 955 +P PV P+ P PE + PPP P PPT P K Sbjct: 10600 K-------KPEVTPVKVPEAPKEVVPEKKVPVPPPKK-------PEVPPTKVPEVPKVAV 10645 Query: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015 P KK + P + PPP EP+ +++ ++ E +P + Sbjct: 10646 PEKKVPEAIPPKPESPPPEV-------------FEEPEEVALEEPPAEVVEEPEPAAPPQ 10692 Query: 1016 ETLPPPAAPPKPG-------KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDS----VVEF 1064 T+PP P+ K L V +P V ++ K P++ + ++ V E Sbjct: 10693 VTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752 Query: 1065 PSP--PSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122 P P P PE +PP ++P V PK V+ +P + PP Sbjct: 10753 PKEVVPEKKVAVPKKPE----VPPAKVPEV------PKKPVLEEKPAVPVPERAESPPPE 10802 Query: 1123 TRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHG 1182 + + + E+ + + P P ++ +P + ++K Sbjct: 10803 VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP-----EKKVPVIKK 10857 Query: 1183 SLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQ 1242 + EP ++ L P PP PPPAPPK D Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRPPP------------------------PPPAPPKEDV 10893 Query: 1243 NTKL 1246 K+ Sbjct: 10894 KEKI 10897 Score = 104 bits (259), Expect = 6e-22 Identities = 114/478 (23%), Positives = 167/478 (34%), Gaps = 74/478 (15%) Query: 585 TQLEESSKARMESMNRPYTSLVPPLSPQPKIVT-PYTASQPSPPLPPPPPPPPPPPPPPP 643 T++ E K + P P SP P++ P + PP P P PP Sbjct: 10635 TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694 Query: 644 -PPPPPLPSQSAPSAGSAAPMF--VKYSTITRLQNASQHSGALF--KPPTPPVMQSQSVK 698 PP P+P + AP+ + P VK + + + + KP PP + Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV-- 10752 Query: 699 PQILVPPNGV-VPPPPPPPP---PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQH 754 P+ +VP V VP P PP P P + + KPA +P+ + PPP + + Sbjct: 10753 PKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV---PVPERAESPPPEVYEEPEE 10809 Query: 755 IT---QVAPPTPPP-------PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP- 803 I ++AP P P +P P P+ P K + P K AP + P Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPE 10869 Query: 804 -----------PTPTPPVPPAK-------KQPAFPASYIPPSPPTPP-VPVPPPTLPKQQ 844 P P PP PP + + A P +P P P V + P +P + Sbjct: 10870 KVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGE 10929 Query: 845 SFCAKP-PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903 K P P VV + + P P +E + L+ V P+ PP + Sbjct: 10930 KKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989 Query: 904 WQPS-------------------SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944 P+ +IP+P+P+ P P PPP P P P P Sbjct: 10990 EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVE--PEPTPIAAP 11047 Query: 945 TASPTPDKSGSPGKKTSKTSSPGG-------KKPPPTPQRNSSIKSSSGAEHPEPKRP 995 P K + + P G K P P ++ SG E P + P Sbjct: 11048 VTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105 Score = 90.1 bits (222), Expect = 1e-17 Identities = 131/583 (22%), Positives = 203/583 (34%), Gaps = 79/583 (13%) Query: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK--------------- 666 ++P P+P P P P P P PP + ++ P P+ K Sbjct: 9787 TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKV 9846 Query: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP-PNGVVPPPPPPPPPPTPGSAM 725 + R+ + + +P M+ + V + VP P V PP P P Sbjct: 9847 FEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPE 9906 Query: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHI---TQVAPPTPPPPPPIP-APLPPQAPPKP 781 + ++ IH+ + +V P P P +P P+P + P Sbjct: 9907 EVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKP-- 9964 Query: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVP---PAKKQPAFPASYIP--PSPPTPPVPVP 836 +P P K P P P VP P K++P P + +P P P P VP Sbjct: 9965 ---VPVP-KKKEAPPAKVPEVPKKPEEKVPVLIPKKEKP--PPAKVPEVPKKPVPEEKVP 10018 Query: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK--PVPANVAPQ- 893 P K ++ AK P P PVP K++ P P P +E+ P K VP + P+ Sbjct: 10019 VPVPKKVEAPPAKVPEVPKKPVPE--KKV-----PVPAPKKVEAPPAKVPEVPKKLIPEE 10071 Query: 894 -SPPAVKAKPKWQPSSIPVPSPDFPPP---PPESSLVFPP---PPPSPVPAPPPPPPPTA 946 P V K + P +P P P P E ++F P +P P Sbjct: 10072 KKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEE 10131 Query: 947 SPTPDKSGSPGKKTSKTSSPGGKKPPP----TPQRNSSIKSSSGAEHPEPKRPSVDSL-- 1000 P++ ++ + P ++ PP P+ + +PK P + Sbjct: 10132 EVLPEEEEVLPEE--EEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPE 10189 Query: 1001 VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDS 1060 + K + P KE PP P P K+ + LP + VL + Sbjct: 10190 IKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP---------KEEEVLPVEVTEE 10240 Query: 1061 VVEFPSPPSDSDFPPPPP---ETELPLPPIEIP-----AVFSGNTSPKVAVVNPQPQQWS 1112 E P S+ + P PP E E PP +P AV T V P + Sbjct: 10241 PEE--EPISEEEIPEEPPSIEEVEEVAPP-RVPEVIKKAVPEAPTPVPKKVEAPPAKVSK 10297 Query: 1113 KMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 K+ +K P P + K ++ + + P +VP+ P Sbjct: 10298 KIPEEKVPVPVQKKEAPPAKVPEVP-KKVPEKKVLVPKKEAVP 10339 Score = 89.0 bits (219), Expect = 3e-17 Identities = 126/504 (25%), Positives = 178/504 (35%), Gaps = 114/504 (22%) Query: 753 QHITQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP 811 ++IT+ P P P P P P P+APP ++ P K P+ + PP P P Sbjct: 9784 EYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEE-KVPVPIPKKLKPPPPKVPEE 9842 Query: 812 P---------------AKKQPAFPASYIPPSP---------PTPPVPVPPPT----LPKQ 843 P K+Q PA+ +P P P P V PP +PK+ Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902 Query: 844 QSFCAKPPPSPLSPVPSVVKQ-------------------IASQFPPPPTPPAMESQPLK 884 P ++ VV I + P P + P K Sbjct: 9903 LE------PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRK 9956 Query: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP----PPPSPVPAPPP 940 PVP P P K P P P+ P P E V P PPP+ VP P Sbjct: 9957 PVPEEKKPVPVPKKKEAP-------PAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPK 10009 Query: 941 PPPPTAS---PTPDKSGSPGKK---TSKTSSPGGKKPPPTPQR----NSSIKSSSGAEHP 990 P P P P K +P K K P K P P P++ + + P Sbjct: 10010 KPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIP 10069 Query: 991 EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP--GVL--QQGCV 1046 E K+P+ + K P +E +P P A P+ ++ +P VL ++ + Sbjct: 10070 EEKKPT--PVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVL 10127 Query: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP---PETELPLPPIEI-PAVFSGNTSPKVA 1102 + VL + E PP + + PP PE E +P E+ P V PKV Sbjct: 10128 PEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEV-----KPKVP 10182 Query: 1103 VVNPQPQQWSKMSVKK--------APP---PTRPKRNDSTRL------------TQAEIS 1139 V P P+ K++ KK APP P PK+ + R+ E Sbjct: 10183 VPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE 10242 Query: 1140 EQPTMATVVPQVPTSPKSSLSVQP 1163 E+P +P+ P S + V P Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAP 10266 Score = 82.0 bits (201), Expect = 3e-15 Identities = 104/421 (24%), Positives = 157/421 (37%), Gaps = 58/421 (13%) Query: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP----PVPPAKKQPAFP 820 PPP +P LP + P+ + +P P + AP V + P P P PVP KK+PA P Sbjct: 9284 PPPKVPE-LPEKPAPEEVAPVPIPKKVEPPAPKVPEV-PKKPVPEEKKPVPVPKKEPAAP 9341 Query: 821 ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMES 880 P P P PVP +P AK +P + VP V K + ++ ES Sbjct: 9342 ----PKVPEVPKKPVPEEKIPVP---VAKKKEAPPAKVPEVQKGVVTEEKITIVTQREES 9394 Query: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940 P P P K K + +P + PPPP +L P P V Sbjct: 9395 PP---------PAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAV--- 9442 Query: 941 PPPPTASPTPDKSGSPGKKT---SKTSSPGGKKPPPTPQRNSSIKSSSGAEH-----PEP 992 P P A P KKT K K PQR + AE E Sbjct: 9443 -PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501 Query: 993 KRPSVDSLVSKFTPPAESGSPSK-ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 + S+ + E ++ E + P KL++ V A+ Sbjct: 9502 EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKR---------VEAEPA 9552 Query: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELP---LPPIEIPAVFSGNTSPKVAVVNPQ- 1107 ++ R + +V P P+ + PPP E P +P ++PA PK V P Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPA-----PVPKKEKVPPPK 9607 Query: 1108 -PQQWSKMSVKKAPPPTRPKRND--STRLTQ--AEISEQPTMATVVPQVPTSPKSSLSVQ 1162 P++ K +K PP K + ++T+ +I+++ + V + PK+ + + Sbjct: 9608 VPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEE 9667 Query: 1163 P 1163 P Sbjct: 9668 P 9668 Score = 80.1 bits (196), Expect = 1e-14 Identities = 98/450 (21%), Positives = 140/450 (31%), Gaps = 96/450 (21%) Query: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS-APSAGSAAPMFVKYSTITRLQNASQ 678 T + P +P P P P P P P+P + AP A Sbjct: 9938 TEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA--------------------- 9976 Query: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLP 738 P V + K +L+P PP P P P P P P Sbjct: 9977 --------KVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAP 10028 Query: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798 P P K + + AP PP +P + P+ P P + P V Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKV 10088 Query: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPS------------------------------- 827 + P P P P +++ F +P Sbjct: 10089 PKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP 10148 Query: 828 PPTPPVPVPPPTLPKQQSFC--------AKPPPSPLSPVPSVVKQIASQFPPPP----TP 875 P VP +P+++ F KP +PVP + K++ + P P Sbjct: 10149 PEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP 10208 Query: 876 PAMESQPLKPVPAN--VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP---ESSLVFPPP 930 PA + K V + P+ + + +P P+ + P PP E V PP Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268 Query: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990 P + P P +P P K +P K SK P K P P ++ E P Sbjct: 10269 VPEVIKKAVPEAP---TPVPKKVEAPPAKVSK-KIPEEKVPVPVQKK----------EAP 10314 Query: 991 EPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020 K P V K P + P KE +PP Sbjct: 10315 PAKVPE----VPKKVPEKKVLVPKKEAVPP 10340 Score = 71.2 bits (173), Expect = 6e-12 Identities = 94/403 (23%), Positives = 128/403 (31%), Gaps = 103/403 (25%) Query: 763 PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822 P P AP PP+ KP++ TS + V P + + P K P Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT-PVQ 9224 Query: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQ----------FPP 871 P V + +++ F A +S VP V K+I ++ P Sbjct: 9225 EEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEP 9284 Query: 872 PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931 PP P + P KP P VAP +P+P PP P + P P Sbjct: 9285 PPKVPEL---PEKPAPEEVAP----------------VPIPKKVEPPAPKVPEVPKKPVP 9325 Query: 932 ----PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987 P PVP P PP P K P P+ + + Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKK--------------------PVPEEKIPVPVAKKK 9365 Query: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047 E P K P V V T + +E PPPA P P K Sbjct: 9366 EAPPAKVPEVQKGV--VTEEKITIVTQREESPPPAVPEIPKK------------------ 9405 Query: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107 K P P + + PPPP LP P+ P+ V P Sbjct: 9406 ----------KVPEERKPVPRKEEEVPPPPKVPALPKKPV-----------PEEKVAVPV 9444 Query: 1108 PQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ 1150 P KKAPPP R + + T + + + ++ VPQ Sbjct: 9445 P------VAKKAPPP-RAEVSKKTVVEEKRFVAEEKLSFAVPQ 9480 Score = 67.8 bits (164), Expect = 6e-11 Identities = 102/460 (22%), Positives = 154/460 (33%), Gaps = 99/460 (21%) Query: 609 LSPQPKIVTPYTASQPSP----PLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664 + P PK+ P +P+P P+P P PP P P P P+P + P Sbjct: 9282 VEPPPKV--PELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVP------- 9332 Query: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724 + + + A+ PP P + + V + + P PP P Sbjct: 9333 -----VPKKEPAA--------PPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379 Query: 725 MAQLK----------PAPCAPSLPQFSAP----PPPLKIHQVQHITQVAPPTPPPPPPIP 770 + + K P P P +P+ P P P K +V PPPP +P Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEV-----------PPPPKVP 9428 Query: 771 APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS--- 827 A LP + P+ V +P P + K APP P +KK ++ Sbjct: 9429 A-LPKKPVPEEKVAVPVPVAKK---------APP---PRAEVSKKTVVEEKRFVAEEKLS 9475 Query: 828 ---PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-------IASQFPPPPTPPA 877 P V + ++ S+ + +S ++ + P Sbjct: 9476 FAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYV 9535 Query: 878 ME------SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931 +E S+ ++ PA V + + KPK P+ I P P P P+ +V Sbjct: 9536 VEEKLHIISKRVEAEPAEVTERQEKKIVLKPK-IPAKIEEPPPAKVPEAPK-KIVPEKKV 9593 Query: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS------- 984 P+PVP PPP P K K K P +R+ I Sbjct: 9594 PAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAV 9653 Query: 985 SGAEHP-------EPKRPSVDSLVSKFTPPAESGSPSKET 1017 + E P EPKR + V K P E P+K T Sbjct: 9654 TKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVT 9693 Score = 58.2 bits (139), Expect = 5e-08 Identities = 109/487 (22%), Positives = 171/487 (35%), Gaps = 91/487 (18%) Query: 727 QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ---APPKPLV 783 Q K P +P PPP K+ + AP P +PAP+P + PPK Sbjct: 9558 QEKKIVLKPKIPAKIEEPPPAKVPE-------APKKIVPEKKVPAPVPKKEKVPPPKVPE 9610 Query: 784 TIPAPTSTKTVAPVVTQAAPPTPTP----PVPPAKKQPAFPASYIPPSPPTPPVPVPPP- 838 P K V P V + P P + +++ A +PP VP P Sbjct: 9611 EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKR 9670 Query: 839 TLPKQQSFCAKP--PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP-------AN 889 +P+++ KP P + V K++ + P E QP+K V A Sbjct: 9671 AVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAY 9730 Query: 890 VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP------------------ESSLVFPPPP 931 + +V+ + +++ +F P E + P Sbjct: 9731 TLEEEAVSVQREEEYEEYE-EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEP 9789 Query: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991 P+P P P P P K +P K K + P K P P P++ + P Sbjct: 9790 EKPIPVKPVP----EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKK---------LKPPP 9836 Query: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP--------------PKPGKLNLSGVNL 1037 PK P V + KE + PAA P P K V + Sbjct: 9837 PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV 9896 Query: 1038 PGV---LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFS 1094 P V L+ V+ + V++ ++ +VE + E +P+ P+++P V Sbjct: 9897 PEVPKELEPEEVAFEEEVVT-HVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEV-- 9953 Query: 1095 GNTSPKVAVVNPQPQQWSKMSV---KKAPP---PTRPKRNDSTRLTQAEISEQPTMATVV 1148 P+ P P++ + V K+APP P PK+ + E+P A V Sbjct: 9954 ----PR----KPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK-V 10004 Query: 1149 PQVPTSP 1155 P+VP P Sbjct: 10005 PEVPKKP 10011 Score = 46.6 bits (109), Expect = 1e-04 Identities = 38/156 (24%), Positives = 55/156 (35%), Gaps = 9/156 (5%) Query: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP----- 655 P V P +P+ V + P+P P P PP P P P+P + P Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAK 9363 Query: 656 --SAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713 A A V+ +T + PP P + + V + P PP Sbjct: 9364 KKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPP 9423 Query: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749 PP P P + + K A P + APPP ++ Sbjct: 9424 PPKVPALPKKPVPEEKVAVPVPVAKK--APPPRAEV 9457 Score = 42.0 bits (97), Expect = 0.004 Identities = 39/146 (26%), Positives = 57/146 (39%), Gaps = 27/146 (18%) Query: 855 LSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914 ++ V V+ A Q P TPP + +P P +PP++ AK + P P Sbjct: 234 IATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSP------TPPSIAAKAQLARQQSPSP-- 285 Query: 915 DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP---------GKKTSKTSS 965 + P P V AP P P + SP S SP +KT ++ Sbjct: 286 ----------IRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTV 335 Query: 966 PGGKKPPPTPQRNSSIKSSSGAEHPE 991 G + PP ++ + SSS AE E Sbjct: 336 ATGPEVPPPWKQEGYVASSSEAEMRE 361 Score = 39.3 bits (90), Expect = 0.024 Identities = 74/348 (21%), Positives = 102/348 (29%), Gaps = 91/348 (26%) Query: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL--SPVPSVVKQIASQFPPPPTPPA 877 PA P PP + P + K + + + + VP V K+I Q P P Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ--KPSRTPV 9223 Query: 878 MESQPLKPVPA----NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE------SSLVF 927 E VPA + A + S+ VP E S V Sbjct: 9224 QEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVE 9283 Query: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987 PPP +P P P P P K P K + KKP Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP----KKPV--------------- 9324 Query: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047 PE K+P P KE PAAPPK Sbjct: 9325 --PEEKKPVP--------------VPKKE----PAAPPK--------------------- 9343 Query: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107 V E P P + P P + PP ++P V G + + + Q Sbjct: 9344 -------------VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390 Query: 1108 PQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155 ++ +V + P P+ + E+ P VP +P P Sbjct: 9391 REESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPK----VPALPKKP 9434 Score = 38.9 bits (89), Expect = 0.031 Identities = 33/111 (29%), Positives = 47/111 (42%), Gaps = 10/111 (9%) Query: 722 GSAMAQL--KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP-PTPPPPPPI-------PA 771 G+A QL K P P P+ +P PP + Q Q +P P P P+ P+ Sbjct: 243 GAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPS 302 Query: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822 P+ +P + T P + + TQA+ P VPP KQ + AS Sbjct: 303 PVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVAS 353 Score = 38.5 bits (88), Expect = 0.041 Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 10/104 (9%) Query: 727 QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ-APPKPLVTI 785 +LKP P +P P P + I V + PP PP P+ P P + PP + + Sbjct: 8931 ELKP----PDIPDSRVPIPTMPIRAVP--PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEV 8984 Query: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829 K VV + TP + K+P P + IP P Sbjct: 8985 TKKAVKKDAKKVVAKPKEMTPREEI---VKKPPPPTTLIPAKAP 9025 Score = 37.0 bits (84), Expect = 0.12 Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 28/103 (27%) Query: 863 KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP--- 919 K+I + PP P + P P+ A V P+ P V A P P +P P PPP Sbjct: 8926 KEIKLELKPPDIPDSRVPIPTMPIRA-VPPEEIPPVVAPP--IPLLLPTPEEKKPPPKRI 8982 Query: 920 ----------------------PPESSLVFPPPPPSPVPAPPP 940 P E + PPPP + +PA P Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAP 9025 Score = 36.6 bits (83), Expect = 0.15 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 12/98 (12%) Query: 808 PPVPPAKKQ-PAFPASYIPPS--PP--TPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVV 862 P +P ++ P P +PP PP PP+P+ PT P+++ KPPP + V Sbjct: 8935 PDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPT-PEEK----KPPPKRIEVTKKAV 8989 Query: 863 KQIASQF--PPPPTPPAMESQPLKPVPANVAPQSPPAV 898 K+ A + P P E P P + P P + Sbjct: 8990 KKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEI 9027 Score = 35.4 bits (80), Expect = 0.34 Identities = 28/113 (24%), Positives = 42/113 (37%), Gaps = 13/113 (11%) Query: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828 +P PP+ PPKP P P S A + Q +P P + P+ P ++ Sbjct: 249 LPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSP-------SPIRHSPS-PVRHVRAPT 300 Query: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881 P+P V P P S SP+ Q ++ P PP + + Sbjct: 301 PSPVRSVSPAA-----RISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQE 348 Score = 34.3 bits (77), Expect = 0.76 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 14/88 (15%) Query: 796 PVVTQAAPPTPTPPVP--PAKKQPAFPASYIPPSPPTPPVPVPPP-------TLPKQQSF 846 P + + P PT P+ P ++ P A IP PTP PPP K+ + Sbjct: 8935 PDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAK 8994 Query: 847 CAKPPPSPLSPVPSVVKQIASQFPPPPT 874 P ++P +VK+ PPPPT Sbjct: 8995 KVVAKPKEMTPREEIVKK-----PPPPT 9017 Score = 33.9 bits (76), Expect = 1.00 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 23/106 (21%) Query: 917 PPPPPESSLVFPPPP-----PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971 PP P+S + P P P +P PP P PTP++ KKP Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEE----------------KKP 8977 Query: 972 PP--TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015 PP ++K + +PK + + K PP + P+K Sbjct: 8978 PPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAK 9023 Score = 32.3 bits (72), Expect = 2.9 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 5/64 (7%) Query: 963 TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPA 1022 TS P K P P + ++KS + PEP P S P E K P + Sbjct: 32661 TSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTE-----KVQHLPVS 32715 Query: 1023 APPK 1026 APPK Sbjct: 32716 APPK 32719 Score = 31.2 bits (69), Expect = 6.5 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 9/64 (14%) Query: 751 QVQHITQVAPPTPP----PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806 Q +T+ A +PP P P + +P ++P + V P P+ K V+P T+ PTP Sbjct: 32651 QKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKR--VKSPEPSHPKAVSPTETK---PTP 32705 Query: 807 TPPV 810 T V Sbjct: 32706 TEKV 32709 Score = 30.8 bits (68), Expect = 8.5 Identities = 39/194 (20%), Positives = 72/194 (37%), Gaps = 16/194 (8%) Query: 521 ESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGH--VRSQSIVSSVFS 578 +S+ D+ + S + + PE +S + + V V+ + V + + Sbjct: 145 QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKT 204 Query: 579 EAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP 638 + Q+ ES + R+E + ++ ++ Q LP PP PP Sbjct: 205 KTIVSTAQISESRQTRIEKKIEAHFD-ARSIATVEMVIDGAAGQQ----LPHKTPPRIPP 259 Query: 639 PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698 P P PP + A A +P +++S + +H + PTP ++S S Sbjct: 260 KPKSRSPTPPSIAAKAQLARQQSPSPIRHS-----PSPVRH----VRAPTPSPVRSVSPA 310 Query: 699 PQILVPPNGVVPPP 712 +I P V P Sbjct: 311 ARISTSPIRSVRSP 324 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 137 bits (345), Expect = 6e-32 Identities = 131/449 (29%), Positives = 154/449 (34%), Gaps = 108/449 (24%) Query: 599 NRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPP---PPPPPPPPLPSQSAP 655 N+P PP PQ P +QP P PPP P PPP P PPPP Q P Sbjct: 45 NKPQGPPSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 102 Query: 656 SAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715 G + + P P + Q PQ P G PPP P Sbjct: 103 PQGDKS-----------------------RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 139 Query: 716 PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP 775 PP G Q P P P PPP ++ + + +PP P PP P Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQ------GPPPQGDNKSR--SSRSPPGKPQGPPPQGGNQP 191 Query: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835 Q PP P P P P P +P P PP P Sbjct: 192 QGPPPP---------------------PGKPQGPPPQGGNKPQ------GPPPPGKPQGP 224 Query: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMESQPLKPVPAN 889 PP K QS PP P P P Q Q PPPP PP ++P P P Sbjct: 225 PPQGDNKSQS-ARSPPGKPQGPPPQGGNQ--PQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281 Query: 890 VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP--------P 941 PQ PP + K + S P P PPP + PPPPP PPP P Sbjct: 282 -KPQGPPP-QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 339 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001 PPP P G G K+ SP GK P Q ++ P+ P Sbjct: 340 PPPGKPQGPPPQG--GSKSRSARSPPGKPQGPPQQEGNN-----------PQGP------ 380 Query: 1002 SKFTPPAESGSPSKETLPP---PAAPPKP 1027 PP G+P + PP P PP+P Sbjct: 381 ----PPPAGGNPQQPQAPPAGQPQGPPRP 405 Score = 124 bits (310), Expect = 7e-28 Identities = 125/431 (29%), Positives = 148/431 (34%), Gaps = 78/431 (18%) Query: 694 SQSVKPQILV------PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747 SQ P ++ PP G P PP PP P P P + PQ PPPP Sbjct: 24 SQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG------PPPQGGNQPQG--PPPP- 74 Query: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807 P P PPP P PP P P K+ +P P P Sbjct: 75 ------------PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122 Query: 808 ---------PPVPPAKKQ-PAFPASYIPPSPPTPPVPV-PPPTLPKQQSFCAKPPPSPLS 856 PP PP K Q P P PP P P PPP + PP P Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182 Query: 857 PVPSVVKQIASQFPPPP------TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910 P P Q Q PPPP PP ++P P P PQ PP + K Q + P Sbjct: 183 PPPQGGNQ--PQGPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPP-QGDNKSQSARSP 238 Query: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPP--------PPPPTASPTPDKSGSPGKKTSK 962 P PPP + PPPPP PPP PPPP P G G K+ Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG--GSKSRS 296 Query: 963 TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP-- 1020 + SP GK P PQ + + P P +P PP + G+ + PP Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQ--------GPPPQGGNKPQGPPPPGK 344 Query: 1021 PAAPPKPGKLNLSGVNLP-----GVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075 P PP G P G QQ + + P G + P P PP Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PAGQPQGPP 403 Query: 1076 PPPETELPLPP 1086 PP+ P P Sbjct: 404 RPPQGGRPSRP 414 Score = 114 bits (286), Expect = 4e-25 Identities = 112/364 (30%), Positives = 133/364 (36%), Gaps = 66/364 (18%) Query: 607 PPLSPQ-PKIVTPYTASQPSPPLPPPPPPPP-------PPPPP-----PPP--------P 645 PP PQ P + S SPP P PPP PPPPP PPP P Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 153 Query: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705 PPP Q P G + S + Q G + P PP + Q PQ P Sbjct: 154 PPPGKPQGPPPQGDNKSRSSR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212 Query: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765 G PPP P PP G +Q +P P PQ PPP +Q P PPP Sbjct: 213 QG-PPPPGKPQGPPPQGDNKSQSARSP--PGKPQ---GPPPQGGNQ--------PQGPPP 258 Query: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825 PP P PPQ KP Q PP P PP + +S P Sbjct: 259 PPGKPQGPPPQGGNKP------------------QGPPPPGKPQGPPPQGGSKSRSSRSP 300 Query: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885 P P PPP Q PP P P P + Q PPPP P + P + Sbjct: 301 PGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGNK--PQGPPPPGKP--QGPPPQG 352 Query: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT 945 + + +SPP P Q + +P PPPP + P PP+ P PP PP Sbjct: 353 GSKSRSARSPPGKPQGPPQQEGN----NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 408 Query: 946 ASPT 949 P+ Sbjct: 409 GRPS 412 Score = 68.2 bits (165), Expect = 5e-11 Identities = 80/308 (25%), Positives = 100/308 (32%), Gaps = 45/308 (14%) Query: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFP 928 P PP ++P P PQ PP QP P P P P PPP + Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGN---QPQG-PPPPPGKPQGPPPQGGNKPQG 91 Query: 929 PPPPSPVPAPPPPPPPTASP--TPDKSGSP----GKKTSKTSSPGGKKPPPTPQRNSSIK 982 PPPP PPP + SP P K P G + P GK P PQ + + Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151 Query: 983 SSSGAEHPEPKRPSVD--SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGV 1040 P+ P D S S+ P G P + P PP PGK G Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-------GP 204 Query: 1041 LQQGCVSAKAPVLSGR-------GKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF 1093 QG + P G+ G + SPP PPP + PP Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP------- 257 Query: 1094 SGNTSPKVAVVNPQPQQWSK------MSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATV 1147 P P PQ +K + PPP ++ S+R + P Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313 Query: 1148 VPQVPTSP 1155 PQ P P Sbjct: 314 QPQGPPPP 321 Score = 63.5 bits (153), Expect = 1e-09 Identities = 87/363 (23%), Positives = 112/363 (30%), Gaps = 59/363 (16%) Query: 893 QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDK 952 +SP + P+ P P PP PP PPP P PPPPP P + Sbjct: 27 ESPSLIAGNPQGAPPQ-GGNKPQGPPSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQ 84 Query: 953 SGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGS 1012 G+ P G PP PQ S + P +P PP + G+ Sbjct: 85 GGN---------KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--------GPPPQGGN 127 Query: 1013 PSKETLPPPA---APPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPP- 1068 + PPP PP G G PG Q S R + P P Sbjct: 128 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187 Query: 1069 -SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKR 1127 + PPPPP PP G P+ +PQ PPP + Sbjct: 188 GNQPQGPPPPPGKPQGPPP-------QGGNKPQGPPPPGKPQ---------GPPPQGDNK 231 Query: 1128 NDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNR----TLQRKSITRHGS 1183 + S R + P PQ P P P + + + + G Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291 Query: 1184 LSSRMSRAEPTATM-------DDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPA 1236 SR SR+ P + PPPPP Q GG+ G PPP Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG--KPQGPPPQGGNKPQG------PPPPG 343 Query: 1237 PPK 1239 P+ Sbjct: 344 KPQ 346 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 136 bits (343), Expect = 1e-31 Identities = 143/513 (27%), Positives = 195/513 (38%), Gaps = 61/513 (11%) Query: 530 SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589 +SS +KS S + ++++ S + TQ S S S++ R E Sbjct: 86 ASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDS--RSVNDEG 143 Query: 590 SSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPS-----PPLPPPPPPPPPPPPPPP 643 SS + ++ NR + +P SPQ +++Q PP P P P P Sbjct: 144 SSDPKDIDQDNRSTSPSIP--SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201 Query: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703 P P LP+ + +A P + T Q +Q P + Q+ ++ PQ Sbjct: 202 PGTPQLPTPGPTPSATAVP---PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR-- 256 Query: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763 PP P PPP P+P + L + PS P + PP + H Q P Sbjct: 257 ------PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310 Query: 764 PPPPPIPAPLPPQAPP--KPLVTIPAPTSTKT-----VAPVVTQAAPPTPTPPVPPAKKQ 816 P PP P LPPQA PL T PA T + Q+ P P+PPA Sbjct: 311 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL- 369 Query: 817 PAFPASYIPPSPPTPPVPVP-----PPTLPKQQSFCAK---PPPSPLSPVPSVVKQIASQ 868 A P PP+ P P +P P PP L F PPP L P+ S+ Sbjct: 370 -AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428 Query: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928 PPP +SQPL P SP A+P S +P P PP V P Sbjct: 429 AHPPPLQLMPQSQPL--------PSSP----AQPPGLTQSQNLPPPPASHPPTGLHQVAP 476 Query: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS-SSGA 987 PP + P P PPP PT + +P + PG PP +S S + G+ Sbjct: 477 QPPFAQHPFVPGGPPPITPPTCPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGS 530 Query: 988 EHPEP----KRPSVDSLVSKFTPPAESGSPSKE 1016 P P K ++D +PP SPS E Sbjct: 531 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 563 Score = 115 bits (288), Expect = 3e-25 Identities = 129/462 (27%), Positives = 169/462 (36%), Gaps = 80/462 (17%) Query: 538 SSSSSIPESQSNHSNQSDSG---VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES---- 590 S+S SIP Q N S+ S + QP +++ + V+ S A QL Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPA-LQAPTGVTPAPSSAPPGTPQLPTPGPTP 214 Query: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650 S + P S P P P+T Q +P L P PP P PPP P P PP Sbjct: 215 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP--- 271 Query: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710 P GSA +A H+ PP S P + P Sbjct: 272 --LQPLTGSAGQ-----------PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG----- 313 Query: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA-PPTPPPPPPI 769 PP P PP A L +P A + P L++ Q Q PP P PP Sbjct: 314 PPQPFGLPPQASQGQAPLGTSPAA------AYPHTSLQLPASQSALQSQQPPREQPLPPA 367 Query: 770 PAPLPPQAPPK--PLVTIPAPTSTKTVAPVVTQAAPPT-----PTPPV-----------P 811 P +P PP P+ +PAP + K P ++ +P + P PP P Sbjct: 368 PLAMPHIKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426 Query: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--- 868 P+ P P +P S P P P PP L + Q+ PP P S P+ + Q+A Q Sbjct: 427 PSAHPP--PLQLMPQSQPLPSSPAQPPGLTQSQNL----PPPPASHPPTGLHQVAPQPPF 480 Query: 869 --------FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ---PSSIPVPSPDFP 917 PPP TPP S P + Q P + A SS P+P+ Sbjct: 481 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 540 Query: 918 PPPPESSLVFPPPPPSPVPAP-PPPPPPTASPTPDKSGSPGK 958 E +L P SP P P P P PT TP + + Sbjct: 541 ----EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 578 Score = 93.2 bits (230), Expect = 1e-18 Identities = 122/437 (27%), Positives = 161/437 (36%), Gaps = 65/437 (14%) Query: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-KPLVTIPAPTSTK 792 +PS+P Q + Q PP P + P P APP P + P PT + Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV-TPAPSSAPPGTPQLPTPGPTPSA 216 Query: 793 TV-----APVVTQAA--PPTPTPPVPPAKKQPAFPASYI--PPSPPTPPVPVPPPTL--- 840 T +P +QA P PT PVP Q A PA + PPSP PP P P P L Sbjct: 217 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-PALHPQRPPSPHPPPHPSPHPPLQPL 275 Query: 841 ------PKQQSFCAKPPPSPLSPVP-SVVKQIASQFPPPPTP---PAMESQPLKPVPANV 890 P S P P P S+ Q P PP P P SQ P+ + Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 335 Query: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP---PPPPSPVPAPPPP-----P 942 A P P Q S++ P P P + L P PPP +P+P P P P Sbjct: 336 AAAYPHTSLQLPASQ-SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394 Query: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLV 1001 P + P+P S PPP + SS+ + + HP P + S Sbjct: 395 PHLSGPSP------------FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442 Query: 1002 SKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV 1061 +P G + LPPP A P L+ P A+ P + G G + Sbjct: 443 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--------FAQHPFVPG-GPPPI 493 Query: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAV----FSGNTSPKVAVVNPQPQQWSKMSVK 1117 P+ PS S PP P T PP A +G +S + V + + Sbjct: 494 TP-PTCPSTST-PPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550 Query: 1118 KAPPPTRPKRNDSTRLT 1134 ++PPP P R+ S T Sbjct: 551 ESPPP--PPRSPSPEPT 565 Score = 73.6 bits (179), Expect = 1e-12 Identities = 97/390 (24%), Positives = 132/390 (33%), Gaps = 97/390 (24%) Query: 830 TPPVPVPPP------TLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPP-PTPPAM 878 +P +P P + +QQ A+PP P+ ++P PS Q P P PTP A Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 217 Query: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938 P A+ AP P A A PVP P + P PPSP P P Sbjct: 218 AVPPQGSPTASQAPNQPQAPTA---------PVPHTHIQQAPA----LHPQRPPSPHPPP 264 Query: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVD 998 P P P P +G P S P + PP P S+++ +HP P +P Sbjct: 265 HPSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGPPGPH---SLQAGPLLQHPGPPQPF-- 318 Query: 999 SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058 P A G T P A P + + LP Q + ++ P Sbjct: 319 ----GLPPQASQGQAPLGTSPAAAYPH-------TSLQLPA--SQSALQSQQPPR----- 360 Query: 1059 DSVVEFPSPPSDSDFP--PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116 E P PP+ P PPP T +P ++PA + P ++ +P M+ Sbjct: 361 ----EQPLPPAPLAMPHIKPPPTTPIP----QLPAPQAHKHPPHLSGPSP-----FSMNA 407 Query: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176 PPP S+ T S P ++PQ P S Sbjct: 408 NLPPPPALKPL--SSLSTHHPPSAHPPPLQLMPQSQPLPSSP------------------ 447 Query: 1177 SITRHGSLSSRMSRAEPTATMDDMALPPPP 1206 A+P LPPPP Sbjct: 448 --------------AQPPGLTQSQNLPPPP 463 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 136 bits (343), Expect = 1e-31 Identities = 143/513 (27%), Positives = 195/513 (38%), Gaps = 61/513 (11%) Query: 530 SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589 +SS +KS S + ++++ S + TQ S S S++ R E Sbjct: 640 ASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDS--RSVNDEG 697 Query: 590 SSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPS-----PPLPPPPPPPPPPPPPPP 643 SS + ++ NR + +P SPQ +++Q PP P P P P Sbjct: 698 SSDPKDIDQDNRSTSPSIP--SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755 Query: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703 P P LP+ + +A P + T Q +Q P + Q+ ++ PQ Sbjct: 756 PGTPQLPTPGPTPSATAVP---PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR-- 810 Query: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763 PP P PPP P+P + L + PS P + PP + H Q P Sbjct: 811 ------PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864 Query: 764 PPPPPIPAPLPPQAPP--KPLVTIPAPTSTKT-----VAPVVTQAAPPTPTPPVPPAKKQ 816 P PP P LPPQA PL T PA T + Q+ P P+PPA Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL- 923 Query: 817 PAFPASYIPPSPPTPPVPVP-----PPTLPKQQSFCAK---PPPSPLSPVPSVVKQIASQ 868 A P PP+ P P +P P PP L F PPP L P+ S+ Sbjct: 924 -AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982 Query: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928 PPP +SQPL P SP A+P S +P P PP V P Sbjct: 983 AHPPPLQLMPQSQPL--------PSSP----AQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030 Query: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS-SSGA 987 PP + P P PPP PT + +P + PG PP +S S + G+ Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGS 1084 Query: 988 EHPEP----KRPSVDSLVSKFTPPAESGSPSKE 1016 P P K ++D +PP SPS E Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 1117 Score = 115 bits (288), Expect = 3e-25 Identities = 129/462 (27%), Positives = 169/462 (36%), Gaps = 80/462 (17%) Query: 538 SSSSSIPESQSNHSNQSDSG---VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES---- 590 S+S SIP Q N S+ S + QP +++ + V+ S A QL Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPA-LQAPTGVTPAPSSAPPGTPQLPTPGPTP 768 Query: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650 S + P S P P P+T Q +P L P PP P PPP P P PP Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP--- 825 Query: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710 P GSA +A H+ PP S P + P Sbjct: 826 --LQPLTGSAGQ-----------PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG----- 867 Query: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA-PPTPPPPPPI 769 PP P PP A L +P A + P L++ Q Q PP P PP Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAA------AYPHTSLQLPASQSALQSQQPPREQPLPPA 921 Query: 770 PAPLPPQAPPK--PLVTIPAPTSTKTVAPVVTQAAPPT-----PTPPV-----------P 811 P +P PP P+ +PAP + K P ++ +P + P PP P Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980 Query: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--- 868 P+ P P +P S P P P PP L + Q+ PP P S P+ + Q+A Q Sbjct: 981 PSAHPP--PLQLMPQSQPLPSSPAQPPGLTQSQNL----PPPPASHPPTGLHQVAPQPPF 1034 Query: 869 --------FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ---PSSIPVPSPDFP 917 PPP TPP S P + Q P + A SS P+P+ Sbjct: 1035 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094 Query: 918 PPPPESSLVFPPPPPSPVPAP-PPPPPPTASPTPDKSGSPGK 958 E +L P SP P P P P PT TP + + Sbjct: 1095 ----EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132 Score = 93.2 bits (230), Expect = 1e-18 Identities = 122/437 (27%), Positives = 161/437 (36%), Gaps = 65/437 (14%) Query: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-KPLVTIPAPTSTK 792 +PS+P Q + Q PP P + P P APP P + P PT + Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV-TPAPSSAPPGTPQLPTPGPTPSA 770 Query: 793 TV-----APVVTQAA--PPTPTPPVPPAKKQPAFPASYI--PPSPPTPPVPVPPPTL--- 840 T +P +QA P PT PVP Q A PA + PPSP PP P P P L Sbjct: 771 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-PALHPQRPPSPHPPPHPSPHPPLQPL 829 Query: 841 ------PKQQSFCAKPPPSPLSPVP-SVVKQIASQFPPPPTP---PAMESQPLKPVPANV 890 P S P P P S+ Q P PP P P SQ P+ + Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP---PPPPSPVPAPPPP-----P 942 A P P Q S++ P P P + L P PPP +P+P P P P Sbjct: 890 AAAYPHTSLQLPASQ-SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948 Query: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLV 1001 P + P+P S PPP + SS+ + + HP P + S Sbjct: 949 PHLSGPSP------------FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 996 Query: 1002 SKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV 1061 +P G + LPPP A P L+ P A+ P + G G + Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--------FAQHPFVPG-GPPPI 1047 Query: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAV----FSGNTSPKVAVVNPQPQQWSKMSVK 1117 P+ PS S PP P T PP A +G +S + V + + Sbjct: 1048 TP-PTCPSTST-PPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104 Query: 1118 KAPPPTRPKRNDSTRLT 1134 ++PPP P R+ S T Sbjct: 1105 ESPPP--PPRSPSPEPT 1119 Score = 73.6 bits (179), Expect = 1e-12 Identities = 97/390 (24%), Positives = 132/390 (33%), Gaps = 97/390 (24%) Query: 830 TPPVPVPPP------TLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPP-PTPPAM 878 +P +P P + +QQ A+PP P+ ++P PS Q P P PTP A Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 771 Query: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938 P A+ AP P A A PVP P + P PPSP P P Sbjct: 772 AVPPQGSPTASQAPNQPQAPTA---------PVPHTHIQQAPA----LHPQRPPSPHPPP 818 Query: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVD 998 P P P P +G P S P + PP P S+++ +HP P +P Sbjct: 819 HPSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGPPGPH---SLQAGPLLQHPGPPQPF-- 872 Query: 999 SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058 P A G T P A P + + LP Q + ++ P Sbjct: 873 ----GLPPQASQGQAPLGTSPAAAYPH-------TSLQLPA--SQSALQSQQPPR----- 914 Query: 1059 DSVVEFPSPPSDSDFP--PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116 E P PP+ P PPP T +P ++PA + P ++ +P M+ Sbjct: 915 ----EQPLPPAPLAMPHIKPPPTTPIP----QLPAPQAHKHPPHLSGPSP-----FSMNA 961 Query: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176 PPP S+ T S P ++PQ P S Sbjct: 962 NLPPPPALKPL--SSLSTHHPPSAHPPPLQLMPQSQPLPSSP------------------ 1001 Query: 1177 SITRHGSLSSRMSRAEPTATMDDMALPPPP 1206 A+P LPPPP Sbjct: 1002 --------------AQPPGLTQSQNLPPPP 1017 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 136 bits (343), Expect = 1e-31 Identities = 143/513 (27%), Positives = 195/513 (38%), Gaps = 61/513 (11%) Query: 530 SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589 +SS +KS S + ++++ S + TQ S S S++ R E Sbjct: 640 ASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDS--RSVNDEG 697 Query: 590 SSKAR-MESMNRPYTSLVPPLSPQPKIVTPYTASQPS-----PPLPPPPPPPPPPPPPPP 643 SS + ++ NR + +P SPQ +++Q PP P P P P Sbjct: 698 SSDPKDIDQDNRSTSPSIP--SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755 Query: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703 P P LP+ + +A P + T Q +Q P + Q+ ++ PQ Sbjct: 756 PGTPQLPTPGPTPSATAVP---PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR-- 810 Query: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763 PP P PPP P+P + L + PS P + PP + H Q P Sbjct: 811 ------PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864 Query: 764 PPPPPIPAPLPPQAPP--KPLVTIPAPTSTKT-----VAPVVTQAAPPTPTPPVPPAKKQ 816 P PP P LPPQA PL T PA T + Q+ P P+PPA Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPL- 923 Query: 817 PAFPASYIPPSPPTPPVPVP-----PPTLPKQQSFCAK---PPPSPLSPVPSVVKQIASQ 868 A P PP+ P P +P P PP L F PPP L P+ S+ Sbjct: 924 -AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982 Query: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928 PPP +SQPL P SP A+P S +P P PP V P Sbjct: 983 AHPPPLQLMPQSQPL--------PSSP----AQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030 Query: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS-SSGA 987 PP + P P PPP PT + +P + PG PP +S S + G+ Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGS 1084 Query: 988 EHPEP----KRPSVDSLVSKFTPPAESGSPSKE 1016 P P K ++D +PP SPS E Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 1117 Score = 115 bits (288), Expect = 3e-25 Identities = 129/462 (27%), Positives = 169/462 (36%), Gaps = 80/462 (17%) Query: 538 SSSSSIPESQSNHSNQSDSG---VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES---- 590 S+S SIP Q N S+ S + QP +++ + V+ S A QL Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPA-LQAPTGVTPAPSSAPPGTPQLPTPGPTP 768 Query: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650 S + P S P P P+T Q +P L P PP P PPP P P PP Sbjct: 769 SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP--- 825 Query: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710 P GSA +A H+ PP S P + P Sbjct: 826 --LQPLTGSAGQ-----------PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG----- 867 Query: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA-PPTPPPPPPI 769 PP P PP A L +P A + P L++ Q Q PP P PP Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAA------AYPHTSLQLPASQSALQSQQPPREQPLPPA 921 Query: 770 PAPLPPQAPPK--PLVTIPAPTSTKTVAPVVTQAAPPT-----PTPPV-----------P 811 P +P PP P+ +PAP + K P ++ +P + P PP P Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980 Query: 812 PAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ--- 868 P+ P P +P S P P P PP L + Q+ PP P S P+ + Q+A Q Sbjct: 981 PSAHPP--PLQLMPQSQPLPSSPAQPPGLTQSQNL----PPPPASHPPTGLHQVAPQPPF 1034 Query: 869 --------FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ---PSSIPVPSPDFP 917 PPP TPP S P + Q P + A SS P+P+ Sbjct: 1035 AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK 1094 Query: 918 PPPPESSLVFPPPPPSPVPAP-PPPPPPTASPTPDKSGSPGK 958 E +L P SP P P P P PT TP + + Sbjct: 1095 ----EEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132 Score = 93.2 bits (230), Expect = 1e-18 Identities = 122/437 (27%), Positives = 161/437 (36%), Gaps = 65/437 (14%) Query: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-KPLVTIPAPTSTK 792 +PS+P Q + Q PP P + P P APP P + P PT + Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV-TPAPSSAPPGTPQLPTPGPTPSA 770 Query: 793 TV-----APVVTQAA--PPTPTPPVPPAKKQPAFPASYI--PPSPPTPPVPVPPPTL--- 840 T +P +QA P PT PVP Q A PA + PPSP PP P P P L Sbjct: 771 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-PALHPQRPPSPHPPPHPSPHPPLQPL 829 Query: 841 ------PKQQSFCAKPPPSPLSPVP-SVVKQIASQFPPPPTP---PAMESQPLKPVPANV 890 P S P P P S+ Q P PP P P SQ P+ + Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSP 889 Query: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP---PPPPSPVPAPPPP-----P 942 A P P Q S++ P P P + L P PPP +P+P P P P Sbjct: 890 AAAYPHTSLQLPASQ-SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948 Query: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG-AEHPEPKRPSVDSLV 1001 P + P+P S PPP + SS+ + + HP P + S Sbjct: 949 PHLSGPSP------------FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 996 Query: 1002 SKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSV 1061 +P G + LPPP A P L+ P A+ P + G G + Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP--------FAQHPFVPG-GPPPI 1047 Query: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAV----FSGNTSPKVAVVNPQPQQWSKMSVK 1117 P+ PS S PP P T PP A +G +S + V + + Sbjct: 1048 TP-PTCPSTST-PPAGPGTSAQ-PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104 Query: 1118 KAPPPTRPKRNDSTRLT 1134 ++PPP P R+ S T Sbjct: 1105 ESPPP--PPRSPSPEPT 1119 Score = 73.6 bits (179), Expect = 1e-12 Identities = 97/390 (24%), Positives = 132/390 (33%), Gaps = 97/390 (24%) Query: 830 TPPVPVPPP------TLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPP-PTPPAM 878 +P +P P + +QQ A+PP P+ ++P PS Q P P PTP A Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 771 Query: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938 P A+ AP P A A PVP P + P PPSP P P Sbjct: 772 AVPPQGSPTASQAPNQPQAPTA---------PVPHTHIQQAPA----LHPQRPPSPHPPP 818 Query: 939 PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVD 998 P P P P +G P S P + PP P S+++ +HP P +P Sbjct: 819 HPSPHPPLQPLTGSAGQPSAP-SHAQPPLHGQGPPGPH---SLQAGPLLQHPGPPQPF-- 872 Query: 999 SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058 P A G T P A P + + LP Q + ++ P Sbjct: 873 ----GLPPQASQGQAPLGTSPAAAYPH-------TSLQLPA--SQSALQSQQPPR----- 914 Query: 1059 DSVVEFPSPPSDSDFP--PPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116 E P PP+ P PPP T +P ++PA + P ++ +P M+ Sbjct: 915 ----EQPLPPAPLAMPHIKPPPTTPIP----QLPAPQAHKHPPHLSGPSP-----FSMNA 961 Query: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK 1176 PPP S+ T S P ++PQ P S Sbjct: 962 NLPPPPALKPL--SSLSTHHPPSAHPPPLQLMPQSQPLPSSP------------------ 1001 Query: 1177 SITRHGSLSSRMSRAEPTATMDDMALPPPP 1206 A+P LPPPP Sbjct: 1002 --------------AQPPGLTQSQNLPPPP 1017 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 129 bits (325), Expect = 1e-29 Identities = 172/695 (24%), Positives = 249/695 (35%), Gaps = 116/695 (16%) Query: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKR----GTQ 586 SSS + S S S S+ S S G S+ QP S S+V + + G+ Sbjct: 410 SSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGST 469 Query: 587 LEESSKARMES---MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPP---PPPPPPPP 640 E S + S ++ SL P P ++ Q +P P PP P Sbjct: 470 AEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ 529 Query: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVM-------- 692 P P PP S + + P S + L G +PP P Sbjct: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS-----PGGSRRPPRSPERTLSPSSGY 584 Query: 693 QSQSVKPQILVPPNGVVPPPPPP----PPPP-------TPGSAMAQLKPAPCAPSLPQFS 741 SQS P + PP G+ PP P PP P +PG++++ + C+ S Sbjct: 585 SSQSGTPTL--PPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS----- 637 Query: 742 APPPPLKIHQVQHITQVAPP-TPPPPPPIPAPL--PPQAPPKPL---------VTIPAPT 789 + P P Q +T + PP P +PAP PP P P +P P Sbjct: 638 SDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV 697 Query: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK 849 ST +P +PPTP + P ++ P PP P P PPP K + Sbjct: 698 STTDASP----QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA 753 Query: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909 P S + P + PPP PPA E Q L ++ +V + PS Sbjct: 754 PSASETAEEP-----LQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS 808 Query: 910 P--VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPG 967 P V SP + + PP P P PAPP P P +++P + P K+ S G Sbjct: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP-GHVAKLPQKEPVGCSKGG 867 Query: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027 G PP + + + PS+ +V + A G+P+ P+AP KP Sbjct: 868 G---PPREDVGAPLVT-----------PSLLQMVRLRSVGAPGGAPTPAL--GPSAPQKP 911 Query: 1028 GKLNLSG----VNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP----- 1078 + LSG V P V KA L+ S + PP PP P Sbjct: 912 LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTAS 971 Query: 1079 ----------ETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128 + E P+ P E A N ++ ++ Q + KAPPP Sbjct: 972 FIFSKGSRKLQLERPVSP-ETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP------ 1024 Query: 1129 DSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163 ++ +P++ P P+ P++ P Sbjct: 1025 ---------VARKPSVGVPPPASPSYPRAEPLTAP 1050 Score = 100 bits (250), Expect = 7e-21 Identities = 113/448 (25%), Positives = 160/448 (35%), Gaps = 84/448 (18%) Query: 613 PKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP-------SAGSAAPMF- 664 P+I+TP PP P P P PPP P P P P+ +AP S A+P Sbjct: 648 PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP 707 Query: 665 -VKYSTITRLQNASQHSGALFKPPTPPVMQSQ----SVKPQILVP--------------P 705 +T+T LQ + S PP+PP + KP+++V P Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDP 767 Query: 706 NGVVPPPPPPPP----------PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755 N PPPPPP P PP + + P P PS P + Sbjct: 768 NW--PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL 825 Query: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS---TKTVAPVVTQAAPPTPTPPVPP 812 P +P PPP PAP P + P + +P +K P P TP + Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885 Query: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC--AKPPPSPLSPVPSVVKQIASQFP 870 + + A P PTP + P P +++ A P P+P S + + V+ A Sbjct: 886 MVRLRSVGA---PGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 Query: 871 P--------PPTPPAMESQPLKPVPANVA---------------PQSPPA---------- 897 P PP E +P + PA+ A P SP Sbjct: 943 ASEGLSSAQPNGPPEAEPRPPQS-PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVA 1001 Query: 898 -VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956 +++ + +P P SP PPP V PPP SP + P P TA PT + Sbjct: 1002 ELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP--SYPRAEPLTAPPTNGLPHTQ 1059 Query: 957 GKKTSKTSSPGGKKPPPTPQRNSSIKSS 984 + + + GG P+ + S Sbjct: 1060 DRTKRELAENGGVLQLVGPEEKMGLPGS 1087 Score = 93.2 bits (230), Expect = 1e-18 Identities = 117/457 (25%), Positives = 164/457 (35%), Gaps = 94/457 (20%) Query: 527 TSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGH---VRSQSIVSSVFSEAWKR 583 TSL S SS +S+ S S+ + SG P G + V + FS + Sbjct: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSK 676 Query: 584 GTQLEESSKARMESMNRPYTSLVPPLSPQ--PKIVTPYTASQPSPPLPP---PPPPPPP- 637 ++ A P SPQ P T T Q SP + PPP PPP Sbjct: 677 PRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPS 736 Query: 638 --PPPPP--------------------------PPPPPPLPSQSAPSAGSAAPMFVKYST 669 PPPPP PPPPPP P + S P + + Sbjct: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796 Query: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA----- 724 + + A SG+ +P S + QI P + P PPP PP P P S+ Sbjct: 797 VASPEPAGP-SGSPELVSSPAASSSSATALQIQPPGS---PDPPPAPPAPAPASSAPGHV 852 Query: 725 --MAQLKPAPCA----PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778 + Q +P C+ P AP + Q+ + V P P P L P AP Sbjct: 853 AKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA----LGPSAP 908 Query: 779 PKPL--------VTIPAPTS-----------TKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819 KPL +PAP+S + + ++ A P P P + PA Sbjct: 909 QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968 Query: 820 PASYI------------PPSPPTPPVPVPPPTLPKQQSFCAKPPP-----SPLSPVPSVV 862 AS+I P SP T + + + +S + PP SP +P P V Sbjct: 969 TASFIFSKGSRKLQLERPVSPETQ-ADLQRNLVAELRSISEQRPPQAPKKSPKAP-PPVA 1026 Query: 863 KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVK 899 ++ + PPP +P ++PL P N P + K Sbjct: 1027 RKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTK 1063 Score = 30.8 bits (68), Expect = 8.5 Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 937 APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP 995 A PP P A + G P +K S++ + G ++ + K ++GAE EP P Sbjct: 3 ARAPPAAPAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAP 61 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 127 bits (319), Expect = 7e-29 Identities = 150/514 (29%), Positives = 202/514 (39%), Gaps = 87/514 (16%) Query: 527 TSLSS-SSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGT 585 TSL+S S+ SG S+ +SQS+ + ++D P+ +Q + S SE G Sbjct: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSP---AQCVCSPPVSE----GP 660 Query: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQP--------SPPLPPPPPPPPP 637 L +S + + + +P + P+ P P + Q +P LPPP P P Sbjct: 661 VLPQSLPS-LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT 719 Query: 638 PPPPPPPP---PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP---PV 691 P P PP PPPL +Q P AP + LQ H P + P Sbjct: 720 GPGQPAPPGQQPPPL-AQPTPLPQVLAPQ-----PVVPLQPVPPHLPPYLAPASQVGAPA 773 Query: 692 MQSQSVKPQILVPPNGVVPPPPPP---PPPPTPGSAMAQLKPAPCAPSLPQFSAPP--PP 746 PQ + P VPP PP PP TP + + L PA P LP + PP PP Sbjct: 774 QLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA--LPDLPTATVPPVPPP 831 Query: 747 LKIHQVQHITQVAPPTPPPPPPIPA-----PLPPQAP---------PKPLVTIP----AP 788 + +A P PP P +P P PP AP P TIP AP Sbjct: 832 QYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP 891 Query: 789 TSTKTVA-----------PVVTQAAP---PTPTPPVPPAKKQ-----PAFPASYIPPSPP 829 ++ PV A P PT PP P Q P PA +PP P Sbjct: 892 PGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPA--LPPQPT 949 Query: 830 TPPVPV--PPPTLPKQQSFCAKP--PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885 PP PV P PTLP Q +P PP P+ P P + PP P P + +PL+P Sbjct: 950 LPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP-PQPMLPPQPVLPPQPALP-VRPEPLQP 1007 Query: 886 -VPANVAPQSPPAVK---AKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941 +P AP + P + P + P P PP ++++ PP P +PA P Sbjct: 1008 HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPP--AAVLSPPLPEVLLPAAPEL 1065 Query: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975 P S S S ++T++ PP P Sbjct: 1066 LPQFPSSLATVSASVQSVPTQTATLLPPANPPLP 1099 Score = 100 bits (250), Expect = 7e-21 Identities = 106/343 (30%), Positives = 136/343 (39%), Gaps = 67/343 (19%) Query: 603 TSLVPPLSP----QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS-APSA 657 T+ VPP+ P P ++ P A+ P PP P P P PP P +P ++ P+A Sbjct: 822 TATVPPVPPPQYFSPAVILPSLAA-PLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA 880 Query: 658 GSAAPMFVK----------YSTITRLQNASQHSGALFK------PPTP--PVMQSQSVKP 699 + P+ +S + +L + A + PP+P V ++ P Sbjct: 881 PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPP 940 Query: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA 759 Q +PP +PP P PP PT L P P P PQ + PP P+ Q + Sbjct: 941 QPALPPQPTLPPQPVLPPQPT-------LPPQPVLP--PQPTRPPQPVLPPQ-----PML 986 Query: 760 PPTP--PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV-----APVVTQAAPPTPTPPVPP 812 PP P PP P +P P P P PA T + AP A PT PVPP Sbjct: 987 PPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPP 1046 Query: 813 AKKQPAFPASYIPPSPPTPPV--PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870 A SPP P V P P LP+ S A S V SV Q A+ P Sbjct: 1047 AAVL----------SPPLPEVLLPAAPELLPQFPSSLATVSAS----VQSVPTQTATLLP 1092 Query: 871 P--PPTP--PAMESQPLKPVPANVAP-QSPPAVKAKPKWQPSS 908 P PP P P + S P V V P Q A + KP P S Sbjct: 1093 PANPPLPGGPGIAS-PCPTVQLTVEPVQEEQASQDKPPGLPQS 1134 Score = 67.8 bits (164), Expect = 6e-11 Identities = 63/231 (27%), Positives = 87/231 (37%), Gaps = 25/231 (10%) Query: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP 770 P P PP P S++ AP Q S+ P + Q ++Q P PP PP Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP-- 1381 Query: 771 APLPPQAPPKPLVTIP----APTSTKTVAPVVTQAA----PPTPTPPVPPAKKQPAFPAS 822 APL P +PP + +P AP ++ P A+ P TP + + Sbjct: 1382 APLAPSSPP--VTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAET 1439 Query: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882 + P P V P P ++ + +P P+P P P+P + QP Sbjct: 1440 HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA--------PEPSPHSGTPQP 1491 Query: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP---ESSLVFPPP 930 PA + P + AV PS P P PP PP ES PPP Sbjct: 1492 ALGQPAPLLPAAVGAVSLATSQLPS--PPLGPTVPPQPPSALESDGEGPPP 1540 Score = 63.9 bits (154), Expect = 9e-10 Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 34/222 (15%) Query: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688 P P P PP P PP SAP + + + Q +G P Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK--EQPSFLASQQLLSQAGPSNPPGA 1379 Query: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748 PP + S P +P +G P P P + G+A P + P + Sbjct: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPAS-GTASQAGGPGTPQGLTSELETSQPLAE 1438 Query: 749 IHQVQHITQ-----VAPPTPPP---------------PPPIPAPLPPQAPPKPLVTIPAP 788 H+ Q +AP TP P PPP P P P P+P + PAP Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAP 1498 Query: 789 TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT 830 V V+ A P+PP+ P +PP PP+ Sbjct: 1499 LLPAAVG-AVSLATSQLPSPPLGPT----------VPPQPPS 1529 Score = 63.9 bits (154), Expect = 9e-10 Identities = 71/221 (32%), Positives = 83/221 (37%), Gaps = 29/221 (13%) Query: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932 P P A ES P P+P + P A K Q SS PS F S P PP Sbjct: 1322 PAPEAPESSP--PLPLSSLPPEASQDSAPYKDQLSSKEQPS--FLASQQLLSQAGPSNPP 1377 Query: 933 SPVPAP--PPPPPPTASP----TPDKSGSPGKKTSKTSSPGGKKPPPTPQ-RNSSIKSSS 985 PAP P PP TA P P S P + S GG P TPQ S +++S Sbjct: 1378 GAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGG---PGTPQGLTSELETSQ 1434 Query: 986 GAEHPEPKRPSVDSLVSKFTP--PA------ESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037 +V LV P PA S +E LPPPA P P SG Sbjct: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPH----SGTPQ 1490 Query: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP 1078 P + G + P G + + PSPP PP PP Sbjct: 1491 PAL---GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPP 1528 Score = 60.5 bits (145), Expect = 1e-08 Identities = 66/249 (26%), Positives = 90/249 (36%), Gaps = 29/249 (11%) Query: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGS--AAPMFVKYST-----ITRLQNASQHSGALFK 685 P P P P PPLP S P S +AP + S+ Q +G Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376 Query: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745 P PP + S P +P +G P P P + G+A P + P Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPAS-GTASQAGGPGTPQGLTSELETSQP 1435 Query: 746 PLKIHQVQHITQ-----VAPPTPPPPPP----IPAPLPPQAPPKPLVTIPAPTSTKTVAP 796 + H+ Q +AP TP P AP P PP P P+P S T P Sbjct: 1436 LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPE---PSPHSG-TPQP 1491 Query: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856 + Q P P +P A + S +P P P VP PP+ + + PP + Sbjct: 1492 ALGQ-----PAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESD---GEGPPPRVG 1543 Query: 857 PVPSVVKQI 865 V S +K + Sbjct: 1544 FVDSTIKSL 1552 Score = 49.3 bits (116), Expect = 2e-05 Identities = 95/445 (21%), Positives = 143/445 (32%), Gaps = 61/445 (13%) Query: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---PPPPLPSQSAPS 656 +P + P +P P+ + AS P PLPPP P P P P P P PL P+ Sbjct: 1447 QPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----LPA 1502 Query: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP 716 A A + A + P+PP+ + +P + +G PPP Sbjct: 1503 AVGAVSL------------------ATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGF 1544 Query: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPP-PPLKIHQVQHITQVAPPTPP----------- 764 T S +L+ +P SA P+++ + P Sbjct: 1545 VDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLAL 1604 Query: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK--------KQ 816 PP P A P+PLV T+ V+ Q + T P +Q Sbjct: 1605 PPVPKEAVSGRVQLPQPLVEKSELAPTR--GAVMEQGTSSSMTAESSPRSMLGYDRDGRQ 1662 Query: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876 A + +P P P V P + + S P PS + + Q P T Sbjct: 1663 VASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLG 1722 Query: 877 AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936 A + P SP + S+ ++ P S PP Sbjct: 1723 ARALGSPRKRPEQQDVSSPAKTVGR-----FSVVSTQDEWTLASPHSLRYSAPPDVYLDE 1777 Query: 937 APPPPPPPTASPTPDKSGS----PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992 AP P A + S G+ S S G + P Q+ +S+ S Sbjct: 1778 APSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFV 1837 Query: 993 KRPSVDSLVSKFTPPAESGSPSKET 1017 K+ + + P+ +GS ET Sbjct: 1838 KKAT-----AFLQRPSRAGSLGPET 1857 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 126 bits (317), Expect = 1e-28 Identities = 186/757 (24%), Positives = 246/757 (32%), Gaps = 211/757 (27%) Query: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQH 679 T P PLPPPP PPPPPPPPPPPPP P + S P + + +ST+ + Sbjct: 238 TGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGL---WSTLHGDAWGPER 294 Query: 680 SGALFKPPTPPVMQSQS---------VKPQILVPPNG--VVPPPPPPPPPPTPGSAMAQL 728 G+ PP Q Q P P G +VP PP P P PG Sbjct: 295 KGS-----APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPG------ 343 Query: 729 KPAPCAPSLPQFSAPPPPLKIHQVQH-----------ITQVAPPTPPPPPPIPAPLPPQA 777 A LP P L+ +VQ T P P PP +P + Sbjct: 344 --AESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSS 401 Query: 778 PP----------KPLVTIPAPTSTKTVAPVVTQ--------------------AAPPTPT 807 +P IP +T A V+ A P Sbjct: 402 SSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSL 461 Query: 808 PPVPPAKKQPAFPASYIPPSPPT--------------------------PPVPVPPPTLP 841 PP P + P P PP PP PP P PPP LP Sbjct: 462 PPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPP-LP 520 Query: 842 KQQSFCAKP-------------PPSPLSPVPSVVKQIAS----------QFPPPP-TPPA 877 ++ F P PP+P +P S + FPPPP + Sbjct: 521 HREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARS 580 Query: 878 MESQPLKPVPANVAPQSPPAVK---AKPKWQPSSI------PVPSPDFPPPP---PESSL 925 ++ P P PA PQ PP V A P PSS P+ P P P++ Sbjct: 581 IDPLPRPPSPAQ-NPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPE 639 Query: 926 VFPPPPPSPVPAPPPPPPPTAS-------------PTP--DKSGSPG------------- 957 V P PPP P+ P P PP PTP D+ P Sbjct: 640 VGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIM 699 Query: 958 --------KKTSKTSSPGGKKP-PPTPQRNSSIKSSSGAE-HPEPKRPSVDSLVSKFTPP 1007 K+ + G P PP + +S++S + P P+V + T Sbjct: 700 KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTT 759 Query: 1008 AESGSPSKETLPPPAAPPKPGKLNLSGVNL------PGVLQQGCVSAKAPVLSG-----R 1056 + + +E PPPA PP P + P + + A VL G R Sbjct: 760 TTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYR 819 Query: 1057 GKDSVVEF-PSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMS 1115 G + V P P + + P PP LPP G +PQP S Sbjct: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQG---------SPQPSASSSSQ 870 Query: 1116 VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG-----FLADLN 1170 + P +R E+P P PT P LS+ P L +++ Sbjct: 871 FSTSGGPWARER---------RAGEEPVPG---PMTPTQPPPPLSLPPARSESEVLEEIS 918 Query: 1171 R---TLQRKSITRHGSLSSRMSRAEPTATMDDMALPP 1204 R TL + + + AEP + + LPP Sbjct: 919 RACETLVERVGRSATDPADPVDTAEPADSGTERLLPP 955 Score = 111 bits (277), Expect = 5e-24 Identities = 162/660 (24%), Positives = 224/660 (33%), Gaps = 138/660 (20%) Query: 619 YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678 Y A + PP+ PP P PP P + G R S+ Sbjct: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGK-----------RRRGCNSE 236 Query: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA---QLKPAPCAP 735 +G P PP PP PPPPPPPPPP PG A + QL Sbjct: 237 QTGLPPGLPLPP-------------PPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWS 283 Query: 736 SL------PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT 789 +L P+ PP + Q + P P P PAP PP + AP Sbjct: 284 TLHGDAWGPERKGSAPPERQEQRHSL--------PHPYPYPAPAYTAHPPGHRLVPAAPP 335 Query: 790 STKTVAP-VVTQAAPPTPTPPVPPAKK------------QPAFPASYIPPSPPTPPVPVP 836 P + P PP ++ PA + +P +P PP +P Sbjct: 336 GPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP-GLP 394 Query: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPP 896 T S + + P P + Q PA+E + + P Sbjct: 395 GTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQ------TPALEVSHHGRLGPSAHSSRKP 448 Query: 897 AVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP------------------ 938 + A S+P P P PPPPP L+ PPPPP+ + P Sbjct: 449 FLGAPAATPHLSLP-PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFG 507 Query: 939 -PPPPPPTASPTPDKSGSPGKKTSK----TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK 993 PP P P P + G G S+ T PPTP +SS S+SG+ P Sbjct: 508 TEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSS-NSNSGSHSSSPA 566 Query: 994 RP-----------SVDSLVSKFTPPAESGSPSKETLPP-----PAAPPKPGKLNLSGVNL 1037 P S+D L PP+ + +P L P P APP N SG Sbjct: 567 GPVSFPPPPYLARSIDPLP---RPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSG--- 620 Query: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP--------PIEI 1089 S + P S R + V FP P PPP P ++ P P P Sbjct: 621 ---------SFRRPE-SPRPR---VSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARG 667 Query: 1090 PAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP 1149 P +F +P + Q ++ ++ + K D + + E +Q A V P Sbjct: 668 PRLFDFPPTP----LEDQFEEPAEFKILPDGLANIMKMLDES--IRKEEEQQQHEAGVAP 721 Query: 1150 QVPTSPKSSLSVQPGFLADL--NRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207 Q P + S+Q F D T ++T + ++ + + ALPPPPP Sbjct: 722 QPPLK-EPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780 Score = 92.4 bits (228), Expect = 2e-18 Identities = 132/543 (24%), Positives = 194/543 (35%), Gaps = 84/543 (15%) Query: 570 QSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIV--------TPYTA 621 +SI + + G + K S+ P+ + P + P + T TA Sbjct: 704 ESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTA 763 Query: 622 SQ-----PSPPLPPPPPP---PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673 +Q P P LPPPPP PPP P PPPPPPP P+ S S KY Sbjct: 764 TQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEG-QKYCYRGTG 822 Query: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC 733 S G P P S PP+G PP P GS P P Sbjct: 823 AAVSTRPG-----PLPTTQYSPG-------PPSGATALPPTSAAPSAQGS------PQPS 864 Query: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793 A S QFS P A P+P P+ P PP PL PA + ++ Sbjct: 865 ASSSSQFSTSGGPW-----------ARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEV 913 Query: 794 VAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853 + + A T V + PA P P+ +PP AK Sbjct: 914 LEEI--SRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQ--------AKEEAG 963 Query: 854 PLSPVPSVVKQIASQFPPP---PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910 ++ V K+ + +S +P A K K + ++ Sbjct: 964 GVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGR-AKAKAKVPKEKSRRVLGNLD 1022 Query: 911 VPSPDF---PPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPG 967 + S + P+ PP+ PAPP P P+A PTP + PGKK ++ +PG Sbjct: 1023 LQSEEIQGREKSRPDLGGASKAKPPT-APAPPSAPAPSAQPTPPSASVPGKK-AREEAPG 1080 Query: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027 PP R +K S +E P PK + + ESG KET A+ + Sbjct: 1081 ----PPGVSRADMLKLRSLSEGP-PKELKIRLI------KVESG--DKETF--IASEVEE 1125 Query: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087 +L ++ + + +++ + G+ ++S + P+ S P E +LP + Sbjct: 1126 RRLRMADLTISHCAADVVRASRNAKVKGKFRESYLS----PAQSVKPKINTEEKLPREKL 1181 Query: 1088 EIP 1090 P Sbjct: 1182 NPP 1184 Score = 75.9 bits (185), Expect = 2e-13 Identities = 122/518 (23%), Positives = 169/518 (32%), Gaps = 114/518 (22%) Query: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPP--PPPPPPPP---------------PPPPLP 650 P SP+P++ P T P + P PPP P P P PP PP PL Sbjct: 625 PESPRPRVSFPKT-----PEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLE 679 Query: 651 SQSAPSA-------GSAAPMFVKYSTITRLQNASQH-SGALFKPP-TPPVMQSQSVKPQI 701 Q A G A M + +I + + QH +G +PP P QS P Sbjct: 680 DQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTD 739 Query: 702 LVPPN---GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758 P V T + + KP P P PPPPL Sbjct: 740 TAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP-------PPPPL----------- 781 Query: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818 PPP P P P PP +P L ++ + + T AA T P+ Sbjct: 782 -AKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL-------- 832 Query: 819 FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878 P + P PP+ +PP + P + SP PS +SQF P A Sbjct: 833 -PTTQYSPGPPSGATALPP---------TSAAPSAQGSPQPSA--SSSSQFSTSGGPWAR 880 Query: 879 ESQP-LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937 E + +PVP + P PP P PP ES ++ Sbjct: 881 ERRAGEEPVPGPMTPTQPP---------------PPLSLPPARSESEVLEEISRACETLV 925 Query: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA---------- 987 T P + P ++ P P + + + SG+ Sbjct: 926 ERVGRSATDPADPVDTAEPADSGTERLLP----PAQAKEEAGGVAAVSGSCKRRQKEHQK 981 Query: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047 EH +R DS+ + P E + +K +P + G L+L + G Sbjct: 982 EHRRHRRACKDSVGRR---PREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQG------RE 1032 Query: 1048 AKAPVLSGRGKDSVVEFPSPPS--DSDFPPPPPETELP 1083 P L G K P+PPS P PP +P Sbjct: 1033 KSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVP 1070 Score = 32.0 bits (71), Expect = 3.8 Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%) Query: 917 PPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQ 976 PP PP S P S PP P P SG P K +PG P P Sbjct: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSK---PYYAPGAPTPRPLHG 88 Query: 977 RNSSIKSSSGAEHPEPKRPSV 997 + S+ A EP +P + Sbjct: 89 KLESLHGCVQALLREPAQPGL 109 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.128 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,754,178 Number of Sequences: 37866 Number of extensions: 6340857 Number of successful extensions: 299915 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1892 Number of HSP's successfully gapped in prelim test: 2164 Number of HSP's that attempted gapping in prelim test: 45071 Number of HSP's gapped (non-prelim): 78698 length of query: 1250 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1136 effective length of database: 13,930,794 effective search space: 15825381984 effective search space used: 15825381984 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.