Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 46852161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
(1003 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 2075 0.0
gi|38202209 methyl-CpG binding domain protein 5 [Homo sapiens] 174 5e-43
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 160 6e-39
gi|163965366 nascent polypeptide-associated complex alpha subuni... 149 1e-35
gi|160707881 formin 2 [Homo sapiens] 143 9e-34
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 135 1e-31
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 135 3e-31
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 133 7e-31
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 124 3e-28
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 123 8e-28
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 122 1e-27
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 118 2e-26
gi|112421108 capicua homolog [Homo sapiens] 116 9e-26
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 107 6e-23
gi|55750053 atrophin-1 [Homo sapiens] 107 6e-23
gi|55750041 atrophin-1 [Homo sapiens] 107 6e-23
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 106 1e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 105 2e-22
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 103 8e-22
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 102 2e-21
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 102 2e-21
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 102 2e-21
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 102 2e-21
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 100 5e-21
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 100 5e-21
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 100 5e-21
gi|153792074 proline rich 12 [Homo sapiens] 100 7e-21
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 100 9e-21
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 100 1e-20
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 98 3e-20
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 2075 bits (5377), Expect = 0.0
Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)
Query: 1 MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTC 60
MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTC
Sbjct: 1 MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTC 60
Query: 61 KCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETT 120
KCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETT
Sbjct: 61 KCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETT 120
Query: 121 CSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG 180
CSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG
Sbjct: 121 CSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG 180
Query: 181 PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS
Sbjct: 181 PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
Query: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300
DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300
Query: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360
LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR
Sbjct: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360
Query: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT 420
PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT
Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT 420
Query: 421 PGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPA 480
PGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPA
Sbjct: 421 PGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPA 480
Query: 481 ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA 540
ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA
Sbjct: 481 ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA 540
Query: 541 LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA
Sbjct: 541 LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
Query: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLS 660
SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLS
Sbjct: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLS 660
Query: 661 PLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGAS 720
PLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGAS
Sbjct: 661 PLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGAS 720
Query: 721 SLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG 780
SLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG
Sbjct: 721 SLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG 780
Query: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS 840
GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS
Sbjct: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS 840
Query: 841 PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFN 900
PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFN
Sbjct: 841 PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFN 900
Query: 901 GQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPT 960
GQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPT
Sbjct: 901 GQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPT 960
Query: 961 RNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLAP 1003
RNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLAP
Sbjct: 961 RNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLAP 1003
>gi|38202209 methyl-CpG binding domain protein 5 [Homo sapiens]
Length = 1494
Score = 174 bits (440), Expect = 5e-43
Identities = 199/672 (29%), Positives = 267/672 (39%), Gaps = 99/672 (14%)
Query: 1 MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTC 60
MNGG E G D+ GG A VP+GWQR V + VLY+SPSG+ LS LEQ ++YLL+DGTC
Sbjct: 1 MNGGKECDGGDKEGGLPAIQVPVGWQRRVDQNGVLYVSPSGSLLSCLEQVKTYLLTDGTC 60
Query: 61 KCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMET- 119
KCGLECPL +PKVFNFDP A V A ++ED+TKLC H+RK +A+ATL++SME
Sbjct: 61 KCGLECPLILPKVFNFDPGAAVKQRTA-EDVKADEDVTKLCIHKRKIIAVATLHKSMEAP 119
Query: 120 --TCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT 177
+ +SPG G + +P PS R G S+ PE F
Sbjct: 120 HPSLVLTSPGGGTN------ATPVVPSRAATPRSVRNKSHEGITNSVMPE---CKNPFKL 170
Query: 178 LAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSS- 236
+ G +P G+ P P L + + + R S
Sbjct: 171 MIGSSNAMGRLYVQELP------------GSQQQELHPVYPRQRLGSSEHGQKSPFRGSH 218
Query: 237 ---LVPSDLGSPPAPHASSSPPSDP-----------PLFHCSDALTP------PPLPPSN 276
P+ GS S SP +DP P FH + +P P PPS
Sbjct: 219 GGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRSNPGFHGAPNSSPIHLNRTPLSPPSV 278
Query: 277 NLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQH---- 332
L H P + ++PL +P ++ P ++++ A H
Sbjct: 279 ML--HGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCN--FSTNMEIPRAMFHHKPPQ 334
Query: 333 --PPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP----PTVFRLLEGRGPQTPRR 386
PP PPPS ++P PS+ + P PT F Q P
Sbjct: 335 GPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPVIINPTSFH--SNVHSQVPMM 392
Query: 387 SRPRAPAPVPQPFSLPEPS------------QPILPSV-LSLLGLPTPGPSHSDGSFNLL 433
+ PA VP P +LP P+ Q + S SL P P H G+ +
Sbjct: 393 NVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRVQHSASTSLSPSPVTSPVHMMGTG--I 450
Query: 434 GSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQ 493
G P SS S + P P TS + P +P S P +PS
Sbjct: 451 GRIEASPQRSRSSSTSSDHGNFMMPPVGPQATSSGIKVPPRSPRSTIGSPRPSMPS---- 506
Query: 494 SPS-EGLGMGAGPACPLPPLAG-------GEAFPFPSPEQGLALSGAGFPGMLGALPLPL 545
SPS + G P P +AG + FP+ G + S PG+LG +PL
Sbjct: 507 SPSTKSDGHHQYKDIPNPLIAGISNVLNTPSSAAFPTASAG-SSSVKSQPGLLG-MPLNQ 564
Query: 546 SLGQP-----PPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
L Q P S LL+ + L G G EG S L
Sbjct: 565 ILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNS--SSSSNSGAVAGSGNTEGHSTL-N 621
Query: 601 SLLPPPPSDLLP 612
++ PP + LLP
Sbjct: 622 TMFPPTANMLLP 633
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 160 bits (405), Expect = 6e-39
Identities = 235/790 (29%), Positives = 297/790 (37%), Gaps = 97/790 (12%)
Query: 115 RSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCR------VPPTTPLNGGPGS--LPP 166
+S+ + HS+ SP S G RP R P ++P GP + P
Sbjct: 207 KSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 167 EPPSVSQAFPTLAGPGGLFPPRLADP----VPSGG--SSSPRFLPRGNAPSPAPPPPPAI 220
P SQ P G L PP++ P P+ G SSSP P + P PPP
Sbjct: 265 APAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD- 321
Query: 221 SLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPA 280
N L ++L PS + P P A SP + P L +PP PPS P+
Sbjct: 322 -------NAATPLPATLPPSPPLATPLPLAPPSPSAPPSL---QTLPSPPATPPSQAPPS 371
Query: 281 HPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPST 340
P Q P S T+ P+ + +P+++ P +P LA S L A P L +
Sbjct: 372 MTTPPMQAPPSLQTIP-PIQVPHSLTSPSLQAPPSP--LALSSLQATTSLGSPTLQATHS 428
Query: 341 LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFS 400
PR AS +S RP+ P PP L P +P +PA P S
Sbjct: 429 FLTMSPRQT--QASLTSPSRPASTPPDSPPLQAPLSL---PASPPLQTSLSPAV--SPLS 481
Query: 401 LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPP----PTLSSGSPPQPRHP 456
P P+ LS L +P S L + + L PP P S +PP P
Sbjct: 482 SPLTIHPL--QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 457 IQPSLPGTTSGSLSSVPGAPAPPAASKAPVV--PSPVLQSPSEGLGMGAGPACPLPP-LA 513
P T+ + + P PP + P+ PSP+ P E A P PP LA
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 514 GGEAFPFPSPEQG-LALSGAGFPGMLGALPL---PLSLGQPP------PSPLLNHSLFGV 563
PSP LA P L PL P PP PSP ++L
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 564 LTGGGGQPPPEPLLPPPGGP--GPPLAPGEP---EGPSLLVASLLPPPPSDLLPPPSAPP 618
L PPP P + P P PP++P + P L A L PPS PP +P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 619 SNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNS 678
+ P LA P A PS P P PPL A P L S
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP--------PPRVPPLLAAPPLQVPPS 771
Query: 679 ALLAATLDPPSGTPPQ-PCVLSAPQ----PGPPTSSVTTATTDPGASSLGKAPSNSGRPP 733
+ + P + PPQ P L+ P P PP S A P A SL +P PP
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA-SLPMSP--LATPP 828
Query: 734 QLLSPLLGASLLGDLSSLTSSPGALPSLLQP-----PGP--LLSG-QLGLQLLPGGGAPP 785
P+L A LL + SP A P+L P PGP +SG +L L L PG PP
Sbjct: 829 PQAPPVLAAPLL----QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
Query: 786 ---PLSEASSP-LACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841
P S S P LA S PE+ PE A+A P A L+A P S
Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSR 942
Query: 842 DPPVPELLTG 851
P P G
Sbjct: 943 GPAPPLAFRG 952
Score = 139 bits (349), Expect = 2e-32
Identities = 230/821 (28%), Positives = 273/821 (33%), Gaps = 152/821 (18%)
Query: 143 PSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPR 202
P+AR P + P P GS P PP A L G + LA+ G ++
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-- 69
Query: 203 FLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFH 262
P AP P S S N A R +PPA + S P S P
Sbjct: 70 ------IPESAPRAGPTRSAGTSSRN--PASRPPASGRGERAPPAKNTSPGPVSSPG--R 119
Query: 263 CSDALTPPPLPP-----SNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG--PGA 315
S P PL S G A++ P SA G G PG
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL--------SAGARRDTSGPTPGT 171
Query: 316 PPFLASSLLSAAAKAQHPPLPPPSTL---QGRRPRAQAPSASHSSSLRPSQRRPRRP--- 369
P + AA P P PS PR SAS S+ PS RRP
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 370 -----PTVFRLLEGRGP-QTPRRS------RPRAPA----PVPQPFSLPEPSQPILP--- 410
P L P +P RS PRAPA P P+ P Q P
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 411 -----SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP---PQPRHPIQPSLP 462
LS L TP PS + +A P P TL P P P P PS P
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351
Query: 463 GT--TSGSLSSVPGAPAPPAASKAPV-----------------VPSPVLQSPSEGLGMG- 502
+ T S + P + APP+ + P+ + SP LQ+P L +
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Query: 503 --AGPACPLPPLAGGEAFPFPSPEQGLA-----LSGAGFPGMLGALPLPLSLGQPPP--- 552
A + P L +F SP Q A A P L PLSL PP
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
Query: 553 ----------SPLLNHSL--FGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
SPL H L L Q P L+ PP LAP + P +
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531
Query: 601 --------SLLPPP---------PSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAE 643
SL PPP L PP P L A PL P +
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591
Query: 644 GAGGP--SGEPFSGLGD--LSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLS 699
P + P GL LSPL PP APP L L A PP+ P P
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL---PPLQAPPSPPASPPLSPLATP 648
Query: 700 APQP-------------GPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLG 746
+PQ PP S A P AS S S PP P L A L
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAAPPLQ 705
Query: 747 DLSSLTSSPGALPSLLQPP-GPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPP 805
S +SP PS PP P LQ+ P A PP+S +++P + L PP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 806 EQ--PEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP 844
Q P P P SP + +P P PP A P P PP
Sbjct: 766 LQVPPSPPASLPMSPLA--KPPPQAPPALATPPLQALPSPP 804
Score = 139 bits (349), Expect = 2e-32
Identities = 196/677 (28%), Positives = 242/677 (35%), Gaps = 129/677 (19%)
Query: 211 SPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPP 270
SP PPPP + GA R L G A S+P + P + + P
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91
Query: 271 PLPPSNNL-----PAH---PGPASQPPVSSATMHLPLVLGPLG-------GAPTVEGPGA 315
PP++ PA PGP S P +S T GPLG TV A
Sbjct: 92 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP----GPLGQKGLRISAEETVARGKA 147
Query: 316 PPFLASSLLSAAAK--AQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
S LSA A+ P PS RR RA + + RP+ RPPT
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA---AGTEVGLPRPAPSARPRPPT-- 202
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
GP+ S P P + PS GL P S L
Sbjct: 203 -----EGPRKSVSSASEHSTTEPSPAARRRPSAGG--------GLQRPASRSLSSSATPL 249
Query: 434 GSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQ 493
S A P + G+P P HP QP G + P PP AP + P+
Sbjct: 250 SSPARSGPS---ARGTPRAPAHPSQPK----PKGLQALRPPQVTPPRKDAAPAL-GPLSS 301
Query: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
SP A P P +G +A P P P+ A PLP +L PPS
Sbjct: 302 SPL---------ATPSP--SGTKARPVPPPDNA-------------ATPLPATL---PPS 334
Query: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGG--PGPPLAPGEPEGPSLLVASLLPPPPSDLL 611
P L L PP P PP P PP P PS+ + PP +
Sbjct: 335 PPLATPL--------PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
Query: 612 PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPP 671
PP P S S PS S L + L P L A
Sbjct: 387 PPIQVPHSLTSPSL-------------------QAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 672 TLIALNSALLAATLDPPS---GTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSN 728
+ + ++ A+L PS TPP L AP P + + T+ + P S L +
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS-PAVSPLSSPLTI 486
Query: 729 SGRPPQLLSPLLGASLLGDLSSL------TSSPGALPSLLQPPGPLLSGQLGLQLLPGGG 782
P Q LS L S LSSL T S A PSL PP L + L + LP
Sbjct: 487 --HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL--ENLPSL- 541
Query: 783 APPPLSEASSPLACLLQSLQIPP-------EQPEAPCL--PPESPASALEPEPARPPLSA 833
APPPL AS+PL L+ PP + P +P PPE+P+S P P PP A
Sbjct: 542 APPPLQTASAPLTT--PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 834 LAPPHGSPDPPVPELLT 850
P G P PP+ L T
Sbjct: 600 SPPLQGLPSPPLSPLAT 616
Score = 127 bits (320), Expect = 4e-29
Identities = 187/675 (27%), Positives = 252/675 (37%), Gaps = 134/675 (19%)
Query: 64 LECPLNVPKVFNFDP-LAP-VTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTC 121
L+ PL++P L+P V+P + + + ++ L +H +A + + +ET
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516
Query: 122 S------HSSPGEGASPQMFHTVSPGPPSAR-------------PPCRVPPTTPLNGGPG 162
S + P +P + + S PP + PPC P PL P
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP--CPLQAPPS 574
Query: 163 SL---PPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPP--- 216
L PPE PS ++A P PP LA P P G SP P P APP
Sbjct: 575 PLTTPPPETPS------SIATPPPQAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLAL 627
Query: 217 ------------PPAISLNAPSYNWGAALRSSLVPSDLGSPPAP--HASSSPPSDPPLFH 262
PP L PS AL L+ + PP+P A SPP+ PP+
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-- 685
Query: 263 CSDALTPPP-LPPSNNLP---AHPGPASQPPVSSATMHLPLVLGPLGGAPTV---EGPGA 315
S + TPP PPS P P P + PP+S + P PL P P +
Sbjct: 686 -SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 316 PPFLASSL-------LSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRR 368
PP S+ L AA Q PP PP S P A+ P + + P +
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS--PLAKPPPQAPPALATPPLQALPS 802
Query: 369 PPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDG 428
PP F G+ P +P S P +P P P + P + P LL +P P P
Sbjct: 803 PPASF---PGQAPFSPSASLPMSPLATPPPQAPPVLAAP-------LLQVP-PSP----- 846
Query: 429 SFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSG---SLSSVPGAPAPPAASKAP 485
P PTL + PR P P + SG +L+ PG P PP+ S +
Sbjct: 847 -----------PASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
Query: 486 VVPSPVL--------QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGM 537
+ P L +P E G +GP G A P P E A G
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPE------GGAAASPPPDAELAACHPAAWSRGP 944
Query: 538 LGALPLPLSLGQPPPSPLLNH--SLFGVLTGGGGQPPPEPLLPPPG----GPGPPLAPGE 591
L + G P P P S G+ T + P E P PG GP P + G+
Sbjct: 945 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP-ESATPAPGALDPGPSPGTSGGK 1003
Query: 592 PEGPSLLVASLLPPPPSDLLPPP-----SAPPSNLLASFLPLLALGPTA---GDGEGSAE 643
+ AS P + L P ++ +LL+ L L A A G G G AE
Sbjct: 1004 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 1063
Query: 644 GAGGPSGEPFSGLGD 658
G GG +G + L D
Sbjct: 1064 G-GGVTGGARAALSD 1077
Score = 48.9 bits (115), Expect = 2e-05
Identities = 74/274 (27%), Positives = 99/274 (36%), Gaps = 58/274 (21%)
Query: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809
+PG L P +PP P+ L + G PL+E + + IP P
Sbjct: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76
Query: 810 APCLPPESPASALEPEPARPPLSAL---APPHGSPDPPVPELLTGRGSG--KRGRRGGGG 864
A P S ++ +RPP S APP + P P GR SG + G G G
Sbjct: 77 AG--PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLGQKG 133
Query: 865 LRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGA 924
LR I+ E ARG+ + P R AL G R +G +P + E G
Sbjct: 134 LR-ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 925 EPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR----- 979
P P P S R R P ++ +S+ + T EPSP AR
Sbjct: 190 -----PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 980 --------------AAVPLPPRARPGRPAKNKRR 999
+A PL AR G A+ R
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Score = 35.4 bits (80), Expect = 0.27
Identities = 79/312 (25%), Positives = 111/312 (35%), Gaps = 47/312 (15%)
Query: 699 SAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGAL 758
SAP+ GP T S T++ +P + P + SP SSPG
Sbjct: 73 SAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSP-----------GPVSSPGRA 120
Query: 759 PSLLQPPGPLLSGQLGLQLLP----GGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP 814
+P GPL GQ GL++ G + S+ A + P +P +
Sbjct: 121 SGTTRP-GPL--GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 815 PESPASALEPEPARPPLSALA-PPHGSPDPPVP---ELLTGRGSGKRGRR--GGGGLRGI 868
S A+ E RP SA PP P V E T S RR GGGL+
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-- 235
Query: 869 NGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKD 928
RPA R S P L R G + + +PR H + G +
Sbjct: 236 ----RPA-SRSLSSSATP----LSSPARSGPSAR--GTPRAP---AHPSQPKPKGLQALR 281
Query: 929 PPPPGPHSEDLKVPPG------VVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAV 982
PP P +D G + S G + + P ++ ++ TL PSP +
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 983 PLPPRARPGRPA 994
PL P + P+
Sbjct: 342 PLAPPSPSAPPS 353
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 819 ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLR-------GINGE 871
A+A P P L PP GSP PP P +T G G G + GI G
Sbjct: 12 AAARTPAARAPGLLTPRPP-GSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 872 ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG--AEPKDP 929
P + G R G + +R +G+ ER+P + G ++ G + P
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN--TSPGPVSSPGRASGTTRP 126
Query: 930 PPPGPHSEDLKVPPGVVR-KSRRGRRRKYNPTRNSNSSRQDITLEPSPT----ARAA--- 981
P G + V R K+ +R + PSP +RAA
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 982 VPLP---PRARPGRPAKNKRRKLA 1002
V LP P ARP P + R+ ++
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVS 210
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 149 bits (377), Expect = 1e-35
Identities = 215/796 (27%), Positives = 277/796 (34%), Gaps = 119/796 (14%)
Query: 122 SHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPE----PPSVSQAFPT 177
S S G SP H SP PPS + TPL+ +LPP+ P V+ FP
Sbjct: 840 SLSFQGSKDSPATTH--SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 178 LAGPGGLFPPRL--------------ADPVPSGGSSSPRFLPRGNAPSP--APPPPPAIS 221
GP P + A P P G +SP P+G AP+P A PP P
Sbjct: 898 -EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS--PKG-APTPPAATPPSPKGG 953
Query: 222 LNAPSYNWGAALRSSLVPSDLGSP--PAPHASSSPPSDPPLFHCSDALTPPP----LPPS 275
PS W ++ PS G P P+P + +PP+ P TP P PP+
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 276 NNLPAHPG-PASQP-PVSSATMHLPLVLGPLGGAPTVEGP-GAPPFLASSLLSAAAKAQH 332
P+ G PA+ P P ++T P G P GAP A++L S
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 333 PPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTP-RRSRPRA 391
P L T P A P + PS + PP G TP + P
Sbjct: 1074 PSLKGAPT-----PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 392 PAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPP 451
PA P P P GL TP P + + A PP P +PP
Sbjct: 1129 PAATP-----PSPKG----------GLATPPPKGAPTT------PAATPPSPKGGLATPP 1167
Query: 452 QPRHPIQPSL-PGTTSGSLS--SVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508
P P+ P + G L+ S GAP PAA+ P P L +PS G PA
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT--PPSPKGGLATPSPK-GAPTTPAAT 1224
Query: 509 LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTG-- 566
P GG A P SP+ A P G P G P P SL G L
Sbjct: 1225 PPSPKGGLATP--SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 567 --GGGQP----PPEP-----LLPPPGGPGPPLA-PGEPEGPSLLVASLLPPPPSDLLPPP 614
G P PP P PP G P PP A P P+G + PPP PP
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG-----SPGTPPPKGAPTPPA 1337
Query: 615 SAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLI 674
PPS LP A P++ G + GP+ + P + PP
Sbjct: 1338 VTPPSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP-------- 1387
Query: 675 ALNSALLAATLDPPSGTPPQPCVLS-APQPGPPTSSVTTATTDPGASSL---GKAPSNSG 730
S + P G P P V+ +P+ P T P L P +
Sbjct: 1388 ---SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 731 RPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLP--GGGAPPPLS 788
+ P +P G + T PS +PP P Q+ P P P+
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK---QVATSSSPKKAPATPAPMG 1501
Query: 789 EASSPLACLLQSLQIP--------PEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS 840
+ P ++P P P A L ++PA+ E PP + P +
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 841 PDPPVPELLTGRGSGK 856
P P P+ S K
Sbjct: 1562 PAIPTPKEAPATPSSK 1577
Score = 148 bits (374), Expect = 2e-35
Identities = 205/785 (26%), Positives = 276/785 (35%), Gaps = 115/785 (14%)
Query: 118 ETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPG------SLPPEP--- 168
++ S ++ +G + + SP S P + PPT + GP S P P
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 169 ---PSVSQAF------------PTLAGPGGLFPPRLADPV-PSGGSSSPRF--------- 203
P S +F PT P G P P+ P G + P+
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 204 -LPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFH 262
P+ +PAP PA+S+ + S R++ P + + P+P + +PP+ P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSS---PKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950
Query: 263 CSDALTP----PPLPPSNNLPA-HPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPP 317
TP P PP+ P+ GPA+ P + T P GG T GAP
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT 1010
Query: 318 FLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLE 377
A + S P P ++ P A PS S + P + P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTP---PAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 378 GRGPQTPR-RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
GP TP + P PA P PS P+ S G P P + L +
Sbjct: 1068 KGGPATPSLKGAPTPPAATP-------PSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 437 AHLPPPPTLSSGSPPQPR----HPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVL 492
H PT + +PP P+ P P T + + S G A P AP P+
Sbjct: 1121 PH-KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 493 QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPP 552
SP GL + P P A PSP+ GLA P GA P + P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATP-----PSPKGGLAT-----PSPKGAPTTPAATPPSPK 1229
Query: 553 SPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASL---LPPPPSD 609
L S G T PP P GGP P G P P+ SL L PP
Sbjct: 1230 GGLATPSPKGAPTTPAATPP-----SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 610 LLPPPS--APPSNLLASFLPLLALGPTAGDGEGSAEGA-GGPSGEPFSGLGDLSPLLFPP 666
P P+ PPS P G +GA P+ P S G SP PP
Sbjct: 1285 GAPNPAVVTPPS-------------PKGGPATSPPKGAPTPPAATPPSPKG--SPGTPPP 1329
Query: 667 LSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP 726
AP A T P GTP P + + GP T S T P A+ P
Sbjct: 1330 KGAPTP--------PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-----P 1376
Query: 727 SNSGRPPQL-LSPLLGASLLGDLSSLTSSPGALP-SLLQPPGPLLSGQLGLQLLPGGGAP 784
S+ G P SP G ++ T SP +P S + P ++ + G P
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPT-SPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 785 P---PLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841
P P+S +P + P P LP +P S EP PA ++ + P +P
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAPKQVATSSSPKKAP 1494
Query: 842 DPPVP 846
P P
Sbjct: 1495 ATPAP 1499
Score = 148 bits (374), Expect = 2e-35
Identities = 211/782 (26%), Positives = 278/782 (35%), Gaps = 148/782 (18%)
Query: 124 SSPGEGASPQMFHTVSPGPPSARP---PCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG 180
++P +P + T S P AR P +P + G P PPS T +
Sbjct: 901 ATPAPKQAPALSMT-SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 181 PGGLFPPRLADPVPSGGSSSPRFLPRGNAPSP--APPPPPAISLNAPSYNWGAALRSSLV 238
PP P P GG ++P P+G AP+P A PP P PS +
Sbjct: 960 KWAPTPPAATPPSPKGGPATPS--PKG-APTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016
Query: 239 PSDLGSP---PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATM 295
PS GSP P P +S+PP A TPP P + A P P P +AT+
Sbjct: 1017 PSPKGSPAATPFPKGASTPP----------AATPP--SPKGSPAATPLPKGAPTTPAATL 1064
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLS-----AAAKAQHPPLPPPSTLQGRRPRAQA 350
P GG T GAP A++ S A + P+PP +T
Sbjct: 1065 P-----SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT---------P 1110
Query: 351 PSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILP 410
PS + P + P P +G P + P PA P P P
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-----PSPKG---- 1161
Query: 411 SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPR----HPIQPSLPGTTS 466
GL TP P + PT + +PP P+ P P T +
Sbjct: 1162 ------GLATPPPKGA----------------PTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 467 GSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL------GMGAGPACPLPPLAGGEAFPF 520
+ S G A P+ AP P+ SP GL G PA P GG A P
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP- 1258
Query: 521 PSPEQGLALSGAGFPGML-GALPLPLSLGQPPPSPLLNHSLFG--VLTGGGGQPPPEPLL 577
P +G A P L G L P G P P+ + S G + G P P
Sbjct: 1259 --PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 578 P--PPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTA 635
P P G PG P G P P ++ PP P P+ PS+ P GPT
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPP-----AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 636 GDGEGSAEGAGGPSGEP---------FSGLGD-LSPLLFP--PLSAPPTLIALNSALLAA 683
S + GGP+ P S GD SP + P P AP T + A +
Sbjct: 1372 PAATPSHK--GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429
Query: 684 --TLDPPSGTP---PQPCVLSAPQPGPPTSS-----VTTATTDPG------------ASS 721
L PP+ TP + SAP+ GP T S A T P +SS
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
Query: 722 LGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGG 781
KAP+ P + +P L A + + ++P + + P LLS + L P
Sbjct: 1490 PKKAPAT---PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546
Query: 782 GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841
PP S P + P P P E+PA+ E + PP + G+P
Sbjct: 1547 ALIPPAMTVPS-----------PKKTPAIP-TPKEAPATPSSKEASSPPAVTPSTYKGAP 1594
Query: 842 DP 843
P
Sbjct: 1595 SP 1596
Score = 131 bits (329), Expect = 4e-30
Identities = 237/928 (25%), Positives = 319/928 (34%), Gaps = 171/928 (18%)
Query: 122 SHSSP-GEGASPQMFHTVS-PGPPSARPPCRVPPTTPL-------NGGPGSLPPEPPSVS 172
S +SP G +S + T S GP SA P + TP + P + P +
Sbjct: 607 SMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGT 666
Query: 173 QAFPTLAGP---GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNW 229
+ T A P G + PV G ++ +P + P P P + AP
Sbjct: 667 STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQ--NTCAPL--- 721
Query: 230 GAALRSSLVPSDLGSPPAPHASSSPPSDPP--LFHCSDALTPPPLPPSNNLPAHPGPASQ 287
+ + +P + SP P A + P + + H S AL P P P AS
Sbjct: 722 ATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS-ALAPVASSPKE-CPTEDSGASA 779
Query: 288 PPVSSATM-HLPLVLGPLGGA--------PTVEGPGAPPFLASSLLSAAAKAQHPPLPPP 338
S T+ +L PLG + PT +G P +L S + + LP
Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839
Query: 339 S-TLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQ 397
S + QG + +P+ +HS + P + P+ L +G P + P P+ V
Sbjct: 840 SLSFQGSK---DSPATTHSPT--PPSPKGAPTPSAVTPLSPKGVTLPPKETP-TPSVVNL 893
Query: 398 PFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPP--PTLSSGSPPQPRH 455
PF P+ P P L + + P + + G A P PT + +PP P+
Sbjct: 894 PFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 456 PIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGG 515
P T S + P A PP+ P PSP G PA P GG
Sbjct: 953 G-----PATPSPKWAPTPPAATPPSPKGGPATPSPK--------GAPTPPAATPPSPKGG 999
Query: 516 EAFPFP----SPEQGLALSGAGFPGMLGALPLPLSLGQPP----PSPLLNHSLFGVLTGG 567
A P P +P S G P A P P PP PSP + + L G
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPA---ATPFPKGASTPPAATPPSPKGSPAATP-LPKG 1055
Query: 568 GGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVAS-----LLPPPPSDLLPPPSAPPSNLL 622
P L P GGP P G P P+ S P P +PP + PPS
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS--- 1112
Query: 623 ASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLA 682
P L G + A PS P GL +P PP AP T A +
Sbjct: 1113 ----PKGGLATPPHKGAPTTPAATPPS--PKGGLA--TP---PPKGAPTTPAATPPSPKG 1161
Query: 683 ATLDPP--------SGTPPQPCV-LSAPQP-GPPTSSVTTATTDPGASSLGKAPSNSGRP 732
PP + TPP P L+ P P G PT T A T P PS G P
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT---TPAATPPSPKGGLATPSPKGAP 1218
Query: 733 --PQLLSPLLGASLLGDLSSLTSSPGALPSL--LQPPGPLLSGQLGLQLLPGGGAPPPLS 788
P P S G L+ T SP P+ PP P GG A PP
Sbjct: 1219 TTPAATPP----SPKGGLA--TPSPKGAPTTPAATPPSP-----------KGGPATPPPK 1261
Query: 789 EASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPEL 848
A +P A SL+ P P +PA P P P A +PP G+P PP
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAP--NPAVVTPPSPKGGP--ATSPPKGAPTPPAATP 1317
Query: 849 LTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPR 908
+ +GS G G P P + P A ++GG
Sbjct: 1318 PSPKGSP--------GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG---------- 1359
Query: 909 RTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQ 968
P P S++ PP + G P S ++
Sbjct: 1360 ----------------------PTTPSSKEGPTPPAATPSHKGG------PAMTPPSPKR 1391
Query: 969 DITL---EPSPTARAAVPLPPRARPGRP 993
+ + PT+ A +PL P+ P P
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
Score = 130 bits (327), Expect = 6e-30
Identities = 203/827 (24%), Positives = 284/827 (34%), Gaps = 99/827 (11%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSP---GEGASPQM 134
P A P GA PA+ K + A L + TT + + P G A+P +
Sbjct: 1023 PAATPFPKGASTPPAATPPSPK------GSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 135 FHTVSPGPPSARPPC-RVPPTTPLNGGPGSLPPE--PPSVSQAFPTLAGPGGLFPPRLAD 191
+P PP+A PP + P TP G +PP PPS T G P
Sbjct: 1077 --KGAPTPPAATPPSPKGGPATPSPKG-APMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133
Query: 192 PVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHAS 251
P P GG ++P P+G +PA PP +P + +PP+P
Sbjct: 1134 PSPKGGLATPP--PKGAPTTPAATPP------SPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 252 SSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP---LVLGPLGGAP 308
+ PS P + A TPP P L A P P P +AT P L GAP
Sbjct: 1186 LATPS-PKGAPTTPAATPP--SPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 309 TVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQG---RRPRAQAPSASHSSSLRPSQRR 365
T P A PP P +L+G P AP+ + + P
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 366 PRRPPTVFRLLEGRGPQTPRRSRPRAP---APVPQPFSLPEP-SQPILPSVL-SLLGLPT 420
PP P +P+ S P AP P + P P P LP+ S G PT
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 421 -----PGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSL-----------PGT 464
GP+ + + G A PP P P P P++ P T
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT 1421
Query: 465 TSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP-LPPLAGGEAFPFPSP 523
G+ + G PPA + + +P +P G + P LP + P+P
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 524 EQGLALS----GAGFPGMLGALPLPLSLGQPP------PS----PLLNHSLFGVLTGGGG 569
+Q S P +GA LP + P PS P+ +
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPAT 1541
Query: 570 QPPPEPLLPP----------PGGPGPPLAPGEP-----EGPSLLVASLL--PPPPSDLLP 612
P E L+PP P P P AP P P + S P P +LL
Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLI 1601
Query: 613 PPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPT 672
PP+ + + P P+ G + G P+ P + S L P S
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP----SSLKDSPTSPASV 1657
Query: 673 LIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRP 732
+ + + A+ P+ P P P ++ + TA T G + S++ P
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT---KKSSATSP 1714
Query: 733 PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASS 792
P P G LS++ +P LP +Q + P G PP S+AS+
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAP-LLP--VQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 793 PLACLLQSLQIPPEQPEAPCLPPESPAS---ALEPEPARPPLSALAP 836
PL +P + + P P S A P P PP P
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP 1818
Score = 121 bits (303), Expect = 4e-27
Identities = 211/832 (25%), Positives = 294/832 (35%), Gaps = 155/832 (18%)
Query: 124 SSPGEGASPQMFHTVSPGPPS--ARPPCRVPPTTPL------NGGPGSLPPE-------- 167
++P +P P P A PP + PTTP GG + PP+
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 168 -PPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPP-PAISLNAP 225
PPS T + G P P P GG ++P P+G +PA PP P L P
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS--PKGAPTTPAATPPSPKGGLATP 1235
Query: 226 SYNWGAALRSSLVPSDLGSP--PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHP- 282
S ++ PS G P P P + +PP+ P TPP N P
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295
Query: 283 ----GPASQPPVSSATMHLPLVLGPLG--GAPTVEGPGAPPFLA------SSLLSAAAKA 330
GPA+ PP + T P G G P +G PP + + L A +
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 331 QHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS--QRRPRRP--------PTVFRLLEGRG 380
PS+ +G P A PS ++ P +R P P P V L +
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 381 PQTPRRSRPRAPAPVPQPFSLPEPS-QPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHL 439
P TP R A P L P+ P+ P GP+ +
Sbjct: 1416 PATPVT---REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD-------- 1464
Query: 440 PPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL 499
PTL + +PP P+ P P T+S S APA PA AP +P+ + SP E
Sbjct: 1465 ---PTLPAVTPPSPKEPPAPKQVATSS----SPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 500 GMGAGPACPLPPLAGGEAFPFPS---PEQGLALSGAGFPG--MLGALPLPLSLGQPPPSP 554
+ P+ P A + P+ P++ L P A+P P P S
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK 1577
Query: 555 LLNHSLFGVLTGGGGQPPPEPLLPPPG--------GPGPP-LAPGEPE-GPSLLVASLLP 604
+ + G P P+ LL PP P PP + P PE GP+ P
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 605 --PP--PSDLLPPPSAPPSNL--LASFLPLLALGPTAGDGEGSAEG---AGGPSGEPF-- 653
PP PS L P++P S + + +P + G A G + + A P P
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 654 ---------SGLGDLSPLLFP----------PLS----APPTLIALNSALLAATLD---- 686
SP + P PLS AP + +S+ A D
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 687 ------PPSGTPPQPCVLSAPQ---PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLS 737
PP P +A + P P ++SV+ A + P + L +P + P Q
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
Query: 738 PLLGASLLGDLSSLTSSPG-ALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLAC 796
P SSPG L S +P P +L L L+P P P+S
Sbjct: 1818 P--------------SSPGLVLESPSKPLAPADEDEL-LPLIP----PEPISGGVP---- 1854
Query: 797 LLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPEL 848
QS+ + P++ +P +P SA +P S D VPEL
Sbjct: 1855 -FQSVLVNMPTPKSAGIPVPTP-SAKQPVTKNNKGSG---TESDSDESVPEL 1901
Score = 102 bits (253), Expect = 2e-21
Identities = 228/923 (24%), Positives = 313/923 (33%), Gaps = 125/923 (13%)
Query: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADP----- 192
VSP P S+ P + PT+P + P+ PS +Q TL P P L DP
Sbjct: 463 VSP-PMSSGPISNIEPTSPAALVMAPVAPKEPS-TQVATTLRIP---VSPPLPDPEDLKN 517
Query: 193 VPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASS 252
+PS S +F + + + PA AP A L + P+ L P A+
Sbjct: 518 LPS--SVLVKFPTQKDLQTV-----PASLEGAPFSPAQAGLTTKKDPTVL---PLVQAA- 566
Query: 253 SPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVE- 311
P + P F + + PL P L A P+ + LG A ++
Sbjct: 567 --PKNSPSFQSTSSSPEIPLSPEATL-AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
Query: 312 ----GP-GAPPFLASSLLSAAAKA-----QHPPLPPPSTLQGRRP--RAQAPSASHSSSL 359
GP A P L SSL++ A P P+T +G +P + SL
Sbjct: 624 DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683
Query: 360 RPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLP 419
P + P + T+ L P P S AP PQ P + + P + + P
Sbjct: 684 AP-KNHPVKEGTLTTL-----PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737
Query: 420 TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPP 479
+ P+ + + +H ++S P S ++ G+L+ + +P+P
Sbjct: 738 SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797
Query: 480 AASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS--PEQGLALSGA-GFPG 536
S +P P + S AGP P+ L+ + S PE L+ G+ P
Sbjct: 798 GVSVSPQTKRPPTKKGS------AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
Query: 537 MLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPP-----PGGPGPPLAP-- 589
+ P G P PS + S GV P P + P P P P AP
Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
Query: 590 -----------------GEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLP----L 628
G P PS A P PP+ P P P+ + P
Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKGA---PTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 629 LALGPTAGDGEGSAEGAGGPSG----EPFSGLGDLSP--LLFPPLSAPPTLIALNSA--L 680
P G S +GA P P G SP PP PP+ +A
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 681 LAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRP-PQLLSPL 739
PP+ TPP P A P P + T A T P PS G P P +P
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP- 1087
Query: 740 LGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAP-PPLSEASSPLACLL 798
S G ++ + +P PP P + GL P GAP P + SP
Sbjct: 1088 --PSPKGGPATPSPKGAPMPPAATPPSP----KGGLATPPHKGAPTTPAATPPSPKG--- 1138
Query: 799 QSLQIPPEQ--PEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGK 856
L PP + P P P SP L PP A P +P P L T G
Sbjct: 1139 -GLATPPPKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194
Query: 857 RGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHN 916
G A P+ G+ P A +GG + T
Sbjct: 1195 PTTPAATPPSPKGGLATPS---PKGAPTTPA--ATPPSPKGGLATPSPKGAPTTP--AAT 1247
Query: 917 GELAEGGAEPKDPPPPGPHSEDLKVPP----GVVRKSRRGRRRKYNPTRNSNSSRQDITL 972
+GG P PPP G + PP G+ +G T S T
Sbjct: 1248 PPSPKGG--PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG-GPATS 1304
Query: 973 EP--SPTARAAVPLPPRARPGRP 993
P +PT AA P P+ PG P
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTP 1327
Score = 90.1 bits (222), Expect = 9e-18
Identities = 147/550 (26%), Positives = 196/550 (35%), Gaps = 78/550 (14%)
Query: 81 PVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSP 140
P GG + P S + + + + + A + S + + EGA+ T S
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA-----TPSK 1430
Query: 141 G---PPSARPPC--RVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPS 195
G PP+ P + P T+ GGP + PS S+ PTL P P
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPAT-----PS-SKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 196 GGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255
SSSP+ P AP AP P I PS + PS P AP A+
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVI----PS----SPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 256 SDPPLFHCSDALTPPPL--PPSNNLPAHPGPASQPPV-SSATMHLPLVLGP--LGGAPTV 310
P +AL PP + P PA P P P SS P + P GAP+
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 311 EGPGAPPFLASSLLSAAAKAQHPP-LPPPSTLQGRRPRAQAPSASHSSS-LRPSQRR--P 366
+ PP + S + +A PP + PPS +G P AP + +S + PS + P
Sbjct: 1597 KELLIPPAVTSP---SPKEAPTPPAVTPPSPEKG--PATPAPKGTPTSPPVTPSSLKDSP 1651
Query: 367 RRPPTVFRLLEGRGPQT----PRRSRPRA-------PAPV------------PQPFSLPE 403
P +V + PQ P + P A PAP PQ
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA 1711
Query: 404 PSQPILPSVLSLLGLPTPG---------PSHSDGSFNLLGSDAHLPPP----PTLSSGSP 450
S PI P + G P P D S G DA P P S S
Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 451 PQPRHPIQPSLPGTTSGSLSSVPGAPA--PPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508
P + LP S S+S+ P P P A S P +P PS + P+ P
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Query: 509 LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGG 568
L P E P PE G F +L +P P S G P P+P + G G
Sbjct: 1832 LAPADEDELLPLIPPEP--ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSG 1889
Query: 569 GQPPPEPLLP 578
+ + +P
Sbjct: 1890 TESDSDESVP 1899
Score = 67.8 bits (164), Expect = 5e-11
Identities = 156/647 (24%), Positives = 232/647 (35%), Gaps = 112/647 (17%)
Query: 238 VPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHL 297
V + LG P P PP CS A PL +N P P++ ++S + +
Sbjct: 34 VTAALGQP-------GPTLPPP---CSPAPQQCPLSAANQASPFPSPST---IASTPLEV 80
Query: 298 PLVLGPLGGA-PTVEGPGAPPFLASSL---LSAAAKAQHPPLPPPSTLQGRRPRAQAPSA 353
P G A P P AP FL + + +S AA A P+ P TL+G P + AP A
Sbjct: 81 PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAP-TLKGT-PSSSAPLA 138
Query: 354 SHSSSLRPSQRRPRRPP---------------TVFRLLEGRGPQTPRRSRPRAPAPV-PQ 397
+ + Q+ PP +V L P P+ + + P+ V P
Sbjct: 139 LVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPN 198
Query: 398 PFSLPEPSQPILPSVLSLLGLP--TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRH 455
P P P P ++S + TP S G +L P TL+ SP
Sbjct: 199 PKGTPSP-----PCIVSTVPYHCVTPMASIQSGVASL----PQTTPTTTLAIASPQVKDT 249
Query: 456 PIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGG 515
I L + S+ G +PPAA PV+ S + G P P+ G
Sbjct: 250 TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS--LGS 307
Query: 516 EAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-LNHSLFGV-LTGGGGQPPP 573
P L S G +LG P +L P + ++HS G PP
Sbjct: 308 HLAP-------LHQSSFGSVQLLGQTG-PSALSDPTVKTISVDHSSTGASYPSQRSVIPP 359
Query: 574 EP----LLPPPGGPGPPLAPGEPEGPSLLVA---------------SLLPPPPSDLLPPP 614
P ++P P +AP +GPS + + SL P L P
Sbjct: 360 LPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSP 419
Query: 615 SAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLI 674
+A L + +P+ ++G T A P + +++ + PP+S+ P
Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP-----TTTFEVATCVSPPMSSGP--- 471
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQ 734
+ ++P T P V++ P P++ V T P + L P
Sbjct: 472 -------ISNIEP---TSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPS- 520
Query: 735 LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPL 794
S L+ DL ++ +S P P L+ + +LP A P +SP
Sbjct: 521 --SVLVKFPTQKDLQTVPASLEGAP--FSPAQAGLTTKKDPTVLPLVQAAP----KNSP- 571
Query: 795 ACLLQSLQIPPEQPEAPCLPPESPA--SALEPEPARPPLSALAPPHG 839
S Q PE P P + A S EP P P S++ P G
Sbjct: 572 -----SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613
Score = 53.9 bits (128), Expect = 7e-07
Identities = 90/369 (24%), Positives = 124/369 (33%), Gaps = 66/369 (17%)
Query: 442 PPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGM 501
P T PQ + P + + PG PP S AP
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP---------------- 53
Query: 502 GAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLF 561
CPL A +A PFPSP +A + P + L LG P +P +L
Sbjct: 54 ---QQCPLS--AANQASPFPSPST-IASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLI 107
Query: 562 GVLTGGGGQPPPEPLLPPPGGPG-PPLAPGEPEGPSLLVASLLPP---------PPSDLL 611
G PP P P P G P + L L P PP+ L
Sbjct: 108 G--------PPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT 159
Query: 612 PPPS---APPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL- 667
PPS A +++ P+ P + +E P G P PP
Sbjct: 160 SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP-----------SPPCI 208
Query: 668 --SAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPT-SSVTTATTDPGASSLGK 724
+ P + +++ + P TP +++PQ T SSV + +PG+ SL K
Sbjct: 209 VSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL-K 267
Query: 725 APSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALP----SLLQPPGPLLSGQLGLQLLPG 780
P + PP LS + + S T+ P P SL PL G L G
Sbjct: 268 GPVS---PPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG 324
Query: 781 GGAPPPLSE 789
P LS+
Sbjct: 325 QTGPSALSD 333
Score = 43.9 bits (102), Expect = 8e-04
Identities = 54/202 (26%), Positives = 73/202 (36%), Gaps = 34/202 (16%)
Query: 665 PPLSAPPTLIALNSALLAA--------TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTD 716
P A ++ ++SAL TL PP PQ C LSA P S +T +
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 717 P-----------GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPP 765
P A LG AP P L+ P + + L +SP P+L P
Sbjct: 77 PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA-----LASPMIAPTLKGTP 131
Query: 766 ---GPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASAL 822
PL L + A PP S P + +S + AP P E P + L
Sbjct: 132 SSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV--ITLSAPIAPSE-PKTNL 188
Query: 823 EPEPARPPLSALAPPHGSPDPP 844
+ P + P G+P PP
Sbjct: 189 N----KVPSEVVPNPKGTPSPP 206
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 143 bits (360), Expect = 9e-34
Identities = 197/658 (29%), Positives = 237/658 (36%), Gaps = 142/658 (21%)
Query: 156 PLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPP 215
P++G PG PP PP +GP F ++ + S S + S + P
Sbjct: 759 PVDGLPGR-PPCPPGAE------SGPQTKFCSEIS-LIVSPRRISVQLDSHQPTQSISQP 810
Query: 216 PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDAL-------T 268
PPP PS W A GS P PH+ S+ S A +
Sbjct: 811 PPP------PSLLWSAG------QGQPGSQP-PHSISTEFQTSHEHSVSSAFKNSCNIPS 857
Query: 269 PPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAA 328
PPPLP + + + PG PP LP + P P+ P PP + +L
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPP---LPGMTVPT--LPSTAIPQPPPLQGTEML---- 908
Query: 329 KAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSR 388
PP PPP G P P A + P PP L G G P
Sbjct: 909 ----PPPPPPLPGAGIPPPPPLPGAG----ILPL------PP-----LPGAGIPPPP--- 946
Query: 389 PRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSG 448
P A +P P LP P LP L G+P P P G +PPPP L
Sbjct: 947 PLPGAAIPPPPPLPGAGIP-LPPPLPGAGIPPPPPLPGAG----------IPPPPPLPGA 995
Query: 449 SPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508
P P P LPG +PGA PP P +P + P G G P P
Sbjct: 996 GIPPP-----PPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPP 1046
Query: 509 LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGG 568
LP G P P P L GAG P PLP G PPP PL G
Sbjct: 1047 LP----GAGIPPPPP-----LPGAGIPP---PPPLP-GAGIPPPPPL----------PGA 1083
Query: 569 GQPPPEPLLPPPGGPGPPLAPGE--PEGPSLLVASLLPPPP--SDLLPPPSAPPSNLLAS 624
G PPP PL P G P PP PG P P L A + PPPP +PPP P +
Sbjct: 1084 GIPPPPPL-PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142
Query: 625 FLPLLALG-----PTAGDG---EGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIAL 676
PL +G P G G GAG P P G+G P P + PP
Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP---- 1198
Query: 677 NSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLL 736
L A + PP PP P + P P PP P +G PP L
Sbjct: 1199 -PPLPGAGIPPP---PPLPGMGIPPAPAPPLP-----------------PPGTGIPPPPL 1237
Query: 737 SPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPL 794
P+ G LL + S T + L PP P SG GL + G+ E P+
Sbjct: 1238 LPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP--SGLFGLGMNQDKGSRKQPIEPCRPM 1293
Score = 137 bits (345), Expect = 5e-32
Identities = 182/598 (30%), Positives = 211/598 (35%), Gaps = 131/598 (21%)
Query: 267 LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPL-------GGAPT--VEGPGAPP 317
LT PP+ P P A P + + L++ P PT + P PP
Sbjct: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814
Query: 318 FLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLE 377
SLL +A + Q P PP ++ + S S S+ + S P PP
Sbjct: 815 ----SLLWSAGQGQ-PGSQPPHSISTEFQTSHEHSVS--SAFKNSCNIPSPPPL------ 861
Query: 378 GRGPQTPRRSR-PRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
P T S P P P LP + P LPS +P P P L G++
Sbjct: 862 ---PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPST----AIPQPPP--------LQGTE 906
Query: 437 AHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGA--PAPPAASKAPVVPSPVLQS 494
PPPP L P P P LPG L +PGA P PP A + P P L
Sbjct: 907 MLPPPPPPLPGAGIPPP-----PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP- 960
Query: 495 PSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSP 554
G PLPP G P P P L GAG P PLP G PPP P
Sbjct: 961 ---------GAGIPLPPPLPGAGIPPPPP-----LPGAGIPP---PPPLP-GAGIPPPPP 1002
Query: 555 LLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGE--PEGPSLLVASLLPPPP---SD 609
L G G PPP PL P G P PP PG P P L A + PPPP +
Sbjct: 1003 L----------PGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1051
Query: 610 LLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSA 669
+ PPP P GAG P P G G P P
Sbjct: 1052 IPPPPPLP--------------------------GAGIPPPPPLPGAGIPPPPPLPGAGI 1085
Query: 670 PPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP-SN 728
PP L A + PP PP P V P P P + + PGA P
Sbjct: 1086 PPP-----PPLPGAGIPPP---PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 729 SGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQL---LPGGGAPP 785
+G PP P +G P LP PP P L G G+ LPG G PP
Sbjct: 1138 AGIPPPPPLPRVGIP----------PPPPLPGAGIPPPPPLPGA-GIPPPPPLPGVGIPP 1186
Query: 786 P--LSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841
P L P L IPP P P +PA L P P L P G P
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Score = 132 bits (333), Expect = 1e-30
Identities = 182/587 (31%), Positives = 218/587 (37%), Gaps = 139/587 (23%)
Query: 78 PLAPVTPGGAGVGPASE--EDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMF 135
P P P GA GP ++ +++ + + RR +V + S + T S S P P +
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLD----SHQPTQSISQPPP--PPSLL 817
Query: 136 HTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPS 195
+ G P ++PP + + SVS AF PP L P
Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTS--------HEHSVSSAFKNSCNIPS--PPPL--PCTE 865
Query: 196 GGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255
SS P G P PPPPP + P+ L S+ +P PP PP
Sbjct: 866 SSSSMPGL---GMVP---PPPPPLPGMTVPT------LPSTAIPQP---PPLQGTEMLPP 910
Query: 256 SDPPLFHCSDALTPPPLPPSNNLPAHPGPAS----QPPVSSATMHLPLVLGPLGGA---- 307
PPL + PPPLP + LP P P + PP+ A + P PL GA
Sbjct: 911 PPPPL-PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP---PPLPGAGIPL 966
Query: 308 -PTVEGPGAPPFLASSLLSAAAKAQHPPLP-----PPSTLQGRRPRAQAPSASHSSSLRP 361
P + G G PP L A PPLP PP L G P P
Sbjct: 967 PPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--------P 1015
Query: 362 SQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE---PSQPILPSVLSLLGL 418
P PP L G G P P A +P P LP P P LP G+
Sbjct: 1016 GAGIPPPPP-----LPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGA----GI 1063
Query: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTL-SSGSPPQPRHP-----IQPSLPGTTSGSLSSV 472
P P P G +PPPP L +G PP P P P LPG +
Sbjct: 1064 PPPPPLPGAG----------IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Query: 473 PGA--PAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPL-----PPLAGGEAFPFPSPEQ 525
PGA P PP A + P P P G G+ P P PP G P P P
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPP----PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP-- 1167
Query: 526 GLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGP 585
L GAG P PLP +G PPP PL G G PPP PL P G P P
Sbjct: 1168 ---LPGAGIPP---PPPLP-GVGIPPPPPL----------PGVGIPPPPPL-PGAGIPPP 1209
Query: 586 PLAPGEPEGPSLLVASLLPPPPSDLLPPPSA---PPSNLLASFLPLL 629
P PG +PP P+ LPPP PP L S PLL
Sbjct: 1210 PPLPGMG----------IPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246
Score = 127 bits (318), Expect = 7e-29
Identities = 153/496 (30%), Positives = 174/496 (35%), Gaps = 131/496 (26%)
Query: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLAD 191
P + T P PP + +PP P G G PP P + P PG PP
Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPP---- 944
Query: 192 PVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHAS 251
P P G++ P P A P PPP P + P PP P A
Sbjct: 945 PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP-------------------PPLPGAG 985
Query: 252 SSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPAS----QPPVSSATMHLPLVLGPLGGA 307
PP PPL + PPPLP + P P P + PP+ A + P
Sbjct: 986 IPPP--PPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--------- 1033
Query: 308 PTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPR 367
P + G G PP PPP G P P A P
Sbjct: 1034 PPLPGAGIPP------------------PPPLPGAGIPPPPPLPGAG----------IPP 1065
Query: 368 RPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE---PSQPILPSVLSLLGLPTPGPS 424
PP L G G P P A +P P LP P P LP V G+P P P
Sbjct: 1066 PPP-----LPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGV----GIPPPPPL 1113
Query: 425 HSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVP--GAPAPPAAS 482
G +PPPP L P P P LPG +P G P PP
Sbjct: 1114 PGAG----------IPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 483 KAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP 542
A + P P L G G P PLP G P P P L G G P P
Sbjct: 1159 GAGIPPPPPLP------GAGIPPPPPLP----GVGIPPPPP-----LPGVGIP---PPPP 1200
Query: 543 LPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGG--PGPPLAP--GEPEGPSLL 598
LP G PPP P L G G P P P LPPPG P PPL P G P P +
Sbjct: 1201 LP-GAGIPPPPP---------LPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVG 1250
Query: 599 VASLLPPPPSDLLPPP 614
++L P LPPP
Sbjct: 1251 SSTLPTPQVCGFLPPP 1266
Score = 110 bits (275), Expect = 7e-24
Identities = 153/525 (29%), Positives = 180/525 (34%), Gaps = 146/525 (27%)
Query: 358 SLRPSQRRPRRPPTVFRLLEGRGPQT-----------PRRSRPRAPAPVPQPFSLPEPSQ 406
+L P P RPP G PQT PRR + + P S+ +P
Sbjct: 756 TLPPVDGLPGRPPCPPGAESG--PQTKFCSEISLIVSPRRISVQLDSHQPTQ-SISQPPP 812
Query: 407 PILPSVLSLLGLPTPG--PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGT 464
P PS+L G PG P HS + ++ ++SS P P LP T
Sbjct: 813 P--PSLLWSAGQGQPGSQPPHS------ISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864
Query: 465 TSGS----LSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPF 520
S S L VP P P P +PS + P PPL G E P
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP--------------PPLQGTEMLPP 910
Query: 521 PSPEQGLALSGAGFP--------GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP 572
P P L GAG P G+L PLP G PPP PL G P
Sbjct: 911 PPPP----LPGAGIPPPPPLPGAGILPLPPLP-GAGIPPPPPL-----------PGAAIP 954
Query: 573 PEPLLPPPGGPGPPLAPGE--PEGPSLLVASLLPPPP---SDLLPPPSAPPSNLLASFLP 627
P P LP G P PP PG P P L A + PPPP + + PPP P
Sbjct: 955 PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---------- 1004
Query: 628 LLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDP 687
GAG P P G G P P PP L A + P
Sbjct: 1005 ----------------GAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGAGIPP 1043
Query: 688 PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP-SNSGRPPQLLSPLLGASLLG 746
P PP P P P P + + PGA P +G PP PL GA +
Sbjct: 1044 P---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLPGAGI-- 1096
Query: 747 DLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPE 806
P LP + PP P L PG G PPP P
Sbjct: 1097 ------PPPPPLPGVGIPPPPPL---------PGAGIPPP------------------PP 1123
Query: 807 QPEAPCLPPES-PASALEPEPARPPLSALAPP--HGSPDPPVPEL 848
P A PP P + + P P P + PP G+ PP P L
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/257 (25%), Positives = 92/257 (35%), Gaps = 45/257 (17%)
Query: 755 PGALPSLLQPPGPLLSGQLGLQLLPGGGA-----PPPLSEASSPLACLLQSLQIPPEQPE 809
P A P+ + P G L P GGA P +A S L+ L +SL P +P+
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291
Query: 810 APCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGIN 869
P P P S PA P + +P S P PE G + RG G
Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSP--SSTAFPFPEAGPGEEAAGAPVRGAGD----T 345
Query: 870 GEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDP 929
E + R PG +W G E +P+R GE E A+ D
Sbjct: 346 DEEGEEDAFEDAPRGSPGE---EWAPEVG-----EDAPQRL------GEEPEEEAQGPDA 391
Query: 930 P-------PPGPHSEDLK-----VPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSP- 976
P P P K P + +R+ ++P+++ N S + I P P
Sbjct: 392 PAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPR-IKRRPEPS 450
Query: 977 ------TARAAVPLPPR 987
TA A+V P +
Sbjct: 451 LSRGSRTALASVAAPAK 467
Score = 33.1 bits (74), Expect = 1.3
Identities = 52/212 (24%), Positives = 72/212 (33%), Gaps = 52/212 (24%)
Query: 279 PAHPGPASQPPVSSATMHLP-LVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPP 337
PA P P + P A + L +LGP GGA E PG+P LSA + LP
Sbjct: 232 PAAP-PTAVSPQPGAFLGLDRFLLGPSGGAG--EAPGSPD--TEQALSALSD-----LP- 280
Query: 338 PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQ 397
SL R P++PP+ L P P +P
Sbjct: 281 -------------------ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSST 321
Query: 398 PFSLPE--PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPP---------PTLS 446
F PE P + G P G +D DA P P +
Sbjct: 322 AFPFPEAGPGE-------EAAGAPVRGAGDTDEEGE---EDAFEDAPRGSPGEEWAPEVG 371
Query: 447 SGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
+P + + G + + +S+PG+PAP
Sbjct: 372 EDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 135 bits (341), Expect = 1e-31
Identities = 240/890 (26%), Positives = 303/890 (34%), Gaps = 133/890 (14%)
Query: 85 GGAGVGPASEE-DMTKLCNHRRKAVAMATLYRSMET---TCSHSSPGEGAS-----PQMF 135
G A + P SE + LC+ KA T+ E CS SP E P
Sbjct: 329 GSAELNPNSEWFENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDAL 388
Query: 136 HTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS--QAFPTLAGPGGLFPPRLADPV 193
+ G P + P P GP +P + Q P L P P L P
Sbjct: 389 YVACQGQPKGGHVTSMQPKEP---GPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE 445
Query: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSS 253
S S P P P + PP L A L L S L PP S
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
Query: 254 PPSDPPLFHCSDALTPPP--LPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVE 311
PP P ++ PP PPS PA P S PP +S + P PL P E
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPS---PALETPLSPPPEAS-PLSPPFEESPL-SPPPEE 560
Query: 312 GPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQA----PSASHSSSLRPSQRRPR 367
P +PP AS L + + P+ PP P +A P S P + P
Sbjct: 561 LPTSPPPEASRL---SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
Query: 368 RPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSD 427
PP E P P +P P P S P + P L ++ +P P S
Sbjct: 618 SPPP-----EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP--LPVVSRLSPPPEESP 670
Query: 428 GSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP-PAASKAPV 486
S PPP + PP+ P TS P +P P + P+
Sbjct: 671 LS----------PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 487 VPSPVLQSPSEGLGMGAGPACPL---PPLAGGEAFPFPSPE-QGLALSGAGFPGMLGALP 542
SP+L P E CP P L+ P SP + LS L P
Sbjct: 721 EESPLLPLPEE------PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
Query: 543 LPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASL 602
L P P L+ G P PE L P P L+P PE P L
Sbjct: 775 EEPCLCAVPEEPHLSPQ----AEGPHLSPQPEELHLSPQTEEPHLSP-VPEEP-----CL 824
Query: 603 LPPPPSDLLPP----PSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG-PSGE-----P 652
P P L P P P + P L P + E E G P+ E P
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
Query: 653 FSGLGDLSPLL-FPPLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQP-GPPTS 708
G LSPLL P LS P P L L L + PSG P L P P PP S
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS----PSGEPSLSPQLMPPDPLPPPLS 940
Query: 709 SVTTATTDPGASSLGK------APSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLL 762
+ TA P S LG+ A +S L +P+L + + + P +P ++
Sbjct: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
Query: 763 QPPGPLLSGQLGLQLLPGGGAPPPLSEASSP-LACLLQSLQIPPEQPEAPCLPPESPASA 821
PP P G P G A P L E P + LLQ +P P + C PP P S
Sbjct: 1001 LPPSP---GS------PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051
Query: 822 LEP----------------------EPARPPLSALAPPHGSPDP-PVPELLTGRGSGKRG 858
P + + P AL P SP P P+ +L S
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPA 1111
Query: 859 RRGGGGLRGINGEARPARG-RKPGSRREPGRLALKWGTRGGFNGQMERSP 907
G+ + P G PGS+ EPG+ T G +++ SP
Sbjct: 1112 L---DDFSGLGEDTAPLDGIDAPGSQPEPGQ------TPGSLASELKGSP 1152
Score = 127 bits (319), Expect = 5e-29
Identities = 222/879 (25%), Positives = 286/879 (32%), Gaps = 185/879 (21%)
Query: 131 SPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA 190
SP + +SP PP A P +PL+ P LP PP + + PP
Sbjct: 529 SPALETPLSP-PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 191 DPVPSGGSSSPRFLPRGNAP-------SPAPPPPPAISLNAPSYNWGAA----------- 232
P+ +S F P +P SP PPP A L+ P + +
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
Query: 233 ----------LRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHP 282
+ S L P SP +P SP S PP + L+PPP + P
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE---ASRLSPPPEDSPTSPPPED 704
Query: 283 GPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQ 342
PAS PP S M LPL PL P E P P +++ P L P
Sbjct: 705 SPASPPPEDS-LMSLPLEESPL--LPLPEEPQLCP-----------RSEGPHLSPRPEEP 750
Query: 343 GRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAP--VPQPFS 400
PR + P L P P P P+ P S P+A P PQP
Sbjct: 751 HLSPRPEEP------HLSPQAEEPHLSPQPEEPCLCAVPEEPHLS-PQAEGPHLSPQPEE 803
Query: 401 LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI--Q 458
L Q P + + P P + + + L P P S SP + P+ +
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 459 PSLPGTTSGSL---SSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGG 515
P P G +P P P S +P++ P L P E PPL+
Sbjct: 864 PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE------------PPLS-- 909
Query: 516 EAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEP 575
P PE+ L LS +G P + L P L PP SP++ P P
Sbjct: 910 -----PLPEE-LPLSPSGEPSLSPQLMPPDPL-PPPLSPIIT---------AAAPPALSP 953
Query: 576 L--LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGP 633
L L P G P P +L + PPP ++ P PP + L P
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPP----------MILPP 1003
Query: 634 TAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPP 693
+ G S +G SP+L PL PP L L PPS P
Sbjct: 1004 SPG-----------------SPVGPASPILMEPL--PPQCSPLLQHSLVPQNSPPSQCSP 1044
Query: 694 QPCVLSAPQPGPPTSSVTTATTDPGASSLG----KAPSNSGRPPQLLSPLLGASLLGDLS 749
LS P P P V + + + P P SPL S +GDLS
Sbjct: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL--PSPMGDLS 1102
Query: 750 SLTSS-----------------------PGALPSLLQPPGPLLSGQLGLQLLPGGGAPPP 786
S PG+ P Q PG L S G +L P
Sbjct: 1103 CPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162
Query: 787 LSEASSPLACLLQSLQIPP----EQPEAPCLPPE---------SPASALEPEPARPPLSA 833
++ C + Q P E+P AP P + S L A
Sbjct: 1163 VTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPG 1222
Query: 834 LAPPHGSPDPPVPELLT---GRGSGKRGRRGGGGLR-----------------GINGEAR 873
P GSPDP L+ G + R G LR G
Sbjct: 1223 SEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGG 1282
Query: 874 PARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHH 912
A G K R P R +K G F G+ R PR H
Sbjct: 1283 KAEGEKGRRRSSPARSRIKQGRSSSFPGR--RRPRGGAH 1319
Score = 94.0 bits (232), Expect = 6e-19
Identities = 210/784 (26%), Positives = 257/784 (32%), Gaps = 116/784 (14%)
Query: 124 SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQ-AFPTLAG-P 181
S PG G P FHT PG P R P+TP L P PS+ A P G
Sbjct: 2216 SRPGAG-QPGEFHTTPPGTP------RHQPSTP----DPFLKPRCPSLDNLAVPESPGVG 2264
Query: 182 GGLFPPRLADPVPSGGSSSPRFLPRG--NAPSPAPPPPPAISLNAPSYNWGAALRSSLVP 239
GG L P P G S + + A SP+ PP +++PS P
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTP 2324
Query: 240 SDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPL 299
+P P AS P P L L P PP+ L P P S P + +
Sbjct: 2325 DVFKAPLTPRASQVEPQSPGL-----GLRPQEPPPAQALA--PSPPSHPDIFRPGSY--- 2374
Query: 300 VLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSL 359
P P P PP + L PP PS R P A S SSS
Sbjct: 2375 -TDPYAQPPLTPRPQPPPPESCCAL--------PPRSLPSDPFSRVP---ASPQSQSSSQ 2422
Query: 360 RPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLP 419
P RP P TPR ++P P +P S P+ P P L P
Sbjct: 2423 SPLTPRPLSAEAFC-----PSPVTPRF---QSPDPYSRPPSRPQSRDPFAP----LHKPP 2470
Query: 420 TPGP--------SHSDGSFNLLGSDAHLPPPPT------LSSGSPPQ-PRHPIQPSLPGT 464
P P S + S G A LP P + SG PP R P + GT
Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGT 2530
Query: 465 TSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLG--MGAGPACPLP-----PLAGGEA 517
S + P A P S P VP P L P G+ G GP P +A G
Sbjct: 2531 PSPMRFTFPQAVGEP--SLKPPVPQPGL-PPPHGINSHFGPGPTLGKPQSTNYTVATGNF 2587
Query: 518 FPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL 577
P SP G + G L L P L P P L + G G P E
Sbjct: 2588 HPSGSP-LGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 578 PPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGD 637
P G G LA E G S L S L + T
Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGL----SQTELEKQRQRQRLRELLIRQQIQRNTLRQ 2702
Query: 638 GEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPT----------LIALNSALLAATLDP 687
+ +A A G G P S + S F LS T L+ L + L+ +
Sbjct: 2703 EKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG 2762
Query: 688 PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASS--LGKAPSNSGRPPQLLSPLLGASLL 745
P P + P P P+S + G S +AP P Q L
Sbjct: 2763 PGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQ-- 2820
Query: 746 GDLSSLTSSPGALPSLL-QPPGPLLSGQ-LGLQL------LPGGGAPPPLSEASSPLACL 797
++ TS A+ + PGP L Q LG L LPG G P P + L
Sbjct: 2821 QQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIEL 2880
Query: 798 LQSLQI-------------PPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP 844
++Q PP++P P L PE R + PP PP
Sbjct: 2881 RHNVQKGLGPGGTPFPGQGPPQRPR--FYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPP 2938
Query: 845 VPEL 848
PEL
Sbjct: 2939 APEL 2942
Score = 68.6 bits (166), Expect = 3e-11
Identities = 137/508 (26%), Positives = 173/508 (34%), Gaps = 102/508 (20%)
Query: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF-PGMLGALPLPLS 546
P+ L+ P + +G+ P P + G P+ GL+ S GF G++P P S
Sbjct: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGS----PTTPAGLSTSADGFLKPPAGSVPGPDS 2155
Query: 547 LGQ-----PP--PSPLLNHSLFGVLTGGGGQPPPEPLLP--PPGGPGPPLAPGEPEGPSL 597
G+ PP P+ + + FG+ P EP P PP P P G P P +
Sbjct: 2156 PGELFLKLPPQVPAQVPSQDPFGLAPAY----PLEPRFPTAPPTYPPYPSPTGAPAQPPM 2211
Query: 598 LVASLLP----------PPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG 647
L AS P PP PS P L L L G G GG
Sbjct: 2212 LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG-----GG 2266
Query: 648 PSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPT 707
+ EP LSP PP + + L A+ PS PP + +P G
Sbjct: 2267 KASEPL-----LSP---PPFGESRKALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHL 2316
Query: 708 SSVTTATTD-------PGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPS 760
+ T D P AS + G PQ P +L SP + P
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPA---------QALAPSPPSHPD 2367
Query: 761 LLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL--------------LQSLQIP-- 804
+ +P G L P PPP S + P L S Q P
Sbjct: 2368 IFRP-GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
Query: 805 --PEQPEAPCLPPESPASALEPEPARPPL-----SALAPPHGSPDPPVPELLTGRGSGKR 857
P EA C P +P +RPP AP H P P PE+ GS
Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH 2486
Query: 858 GRRGGGGL-----RGINGE--ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRT 910
G GG G GE A+ G+ P R PG G F G SP R
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG--------TGAFVG--TPSPMRF 2536
Query: 911 HHWQHNGE--LAEGGAEPKDPPPPGPHS 936
Q GE L +P PPP G +S
Sbjct: 2537 TFPQAVGEPSLKPPVPQPGLPPPHGINS 2564
Score = 67.4 bits (163), Expect = 6e-11
Identities = 139/539 (25%), Positives = 179/539 (33%), Gaps = 125/539 (23%)
Query: 122 SHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181
+H+S G G P G A+ P PP + G G+ P + FP G
Sbjct: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVG- 2543
Query: 182 GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSD 241
P L PVP G P + P P P + + + N+ +
Sbjct: 2544 ----EPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPS--------- 2590
Query: 242 LGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
GSP P + S+ S + S P LPP PA G S P +S +
Sbjct: 2591 -GSPLGPSSGSTGES----YGLSPLRPPSVLPP----PAPDG--SLPYLSHGASQRSGIT 2639
Query: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRP 361
P+ E PG + SSL +A P Q P S S
Sbjct: 2640 SPV---EKREDPGTG--MGSSLATA-----------------ELPGTQDPGMSGLSQTEL 2677
Query: 362 SQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPA---PVPQPFSL-PEPSQPILPSV----- 412
++R R+ + + T R+ + A A V P S EPS P +
Sbjct: 2678 EKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQT 2737
Query: 413 --------LSLLGLP---TPGPSHSDGSFNLLGSDAHL--PPPPTLSSGSPPQPRHPIQP 459
SL+GLP GP GSF SD L PPPP S R +
Sbjct: 2738 PFAGTQDKSSLVGLPPSKLSGPILGPGSF---PSDDRLSRPPPPATPSSMDVNSRQLV-- 2792
Query: 460 SLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFP 519
GS + AP P + P+ Q + A A FP
Sbjct: 2793 ------GGSQAFYQRAPYPGSL--------PLQQQQQQLWQQQQATAATSMRFAMSARFP 2838
Query: 520 -FPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-------LNHSLFGVLTGGGGQP 571
P PE G G+ G+ LP P G+P P P L H++ L G GG P
Sbjct: 2839 STPGPELGRQALGSPLAGISTRLPGP---GEPVPGPAGPAQFIELRHNVQKGL-GPGGTP 2894
Query: 572 PPEPLLPPPGGPGPPLAPG-----------EPEGPSLLVASLLPPPPSDLLPPPSAPPS 619
P G GPP P PEG L S LPP PSAPP+
Sbjct: 2895 FP--------GQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP------QKPSAPPA 2939
Score = 66.2 bits (160), Expect = 1e-10
Identities = 179/740 (24%), Positives = 240/740 (32%), Gaps = 131/740 (17%)
Query: 56 SDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYR 115
S GT GLE L P VF AP+TP + V P S L ++ L
Sbjct: 2311 SSGTHLGGLE--LKTPDVFK----APLTPRASQVEPQSPG----LGLRPQEPPPAQALAP 2360
Query: 116 SMETTCSHSSPGEGASP--QMFHTVSPGPPSARPPCRVPPTT----PLNGGPGSLPPEPP 169
S + PG P Q T P PP C +PP + P + P S +
Sbjct: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSS 2420
Query: 170 SVSQAFPTLAGPGGLFP----PRLADPVPSGGSSSPRFLPRGNAP-----SPAPPPPPAI 220
S S P P PR P P S P P+ P P P PP +
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPY---SRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
Query: 221 SLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS-DPPLFHCSD---ALTPPPLPPSN 276
+ A S +L + P+ L + PA + PS PP F S A P P
Sbjct: 2478 AFKAGSLAH-TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF 2536
Query: 277 NLPAHPG-PASQPPVSSATMHLPLVLGP-LGGAPTVEGPGAPPF-------------LAS 321
P G P+ +PPV + P + G PT+ P + + L
Sbjct: 2537 TFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596
Query: 322 SLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRP---RRPPTVFRLLEG 378
S S PL PPS L P P SH +S R P R P G
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGT-----G 2651
Query: 379 RGPQTPRRSRPRAPAPVPQPFSLPEPS--------------QPILPSVLSLLGLPTPGPS 424
G P P S E Q I + L +
Sbjct: 2652 MGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAA 2711
Query: 425 HSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSV---PGA-PAPPA 480
+ G G++ P LS G P + SL G LS PG+ P+
Sbjct: 2712 GAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDR 2771
Query: 481 ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA 540
S+ P +P + +G G +AF +P +PG L
Sbjct: 2772 LSRPPPPATPSSMDVNSRQLVG-----------GSQAFYQRAP----------YPGSLPL 2810
Query: 541 LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
L Q + F + P PGP L P ++
Sbjct: 2811 QQQQQQLWQQQQATAATSMRFAMSARF------------PSTPGPELGRQALGSPLAGIS 2858
Query: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLS 660
+ LP P + +P P+ P A F+ L + + GP G PF G G
Sbjct: 2859 TRLPGP-GEPVPGPAGP-----AQFIEL----------RHNVQKGLGPGGTPFPGQGPPQ 2902
Query: 661 PLLFPPLSAPPTLIALNSAL-LAATLDPPS--GTPPQPCVLSAPQPGPPTSSVTTATTDP 717
F P+S P +A LA + PP PP P + ++ P P T T T
Sbjct: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPT--- 2959
Query: 718 GASSLGKAPSNS--GRPPQL 735
G + + PS++ GRP L
Sbjct: 2960 GLELVNRPPSSTELGRPNPL 2979
Score = 54.3 bits (129), Expect = 6e-07
Identities = 131/481 (27%), Positives = 165/481 (34%), Gaps = 107/481 (22%)
Query: 169 PSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYN 228
P Q GPG P + S G+ P L G + P + + PS +
Sbjct: 3987 PQQQQQQQVALGPG--MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTH 4044
Query: 229 WGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQP 288
G P +G+ P A+ P L S L P P QP
Sbjct: 4045 QGG-------PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP-------------QP 4084
Query: 289 PVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRA 348
SS + PL L PG S LL A H L G +
Sbjct: 4085 QPSSLQLQPPLRL-----------PGQQQQQVS-LLHTAGGGSHGQL-------GSGSSS 4125
Query: 349 QAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPI 408
+A S H + +PS +P ++ + L GPQ P RP PQP P+P P+
Sbjct: 4126 EASSVPHLLA-QPSVSLGDQPGSMTQNL--LGPQQPMLERPMQNNTGPQP---PKPG-PV 4178
Query: 409 LPSVLSLLG---LPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTT 465
L S L G +PT G + L G A P LS PQ + +Q L
Sbjct: 4179 LQSGQGLPGVGIMPTVGQLRA----QLQGVLAKNPQLRHLS----PQQQQQLQALLMQRQ 4230
Query: 466 SGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQ 525
+V P P SP +GL +G P GG FP P+
Sbjct: 4231 LQQSQAVRQTP--------PYQEPGTQTSPLQGL-LGC------QPQLGG----FPGPQT 4271
Query: 526 G-LALSGAG----FPGMLGALPLPLSLG--------QPPPSPLLNHSLFGVLTGGGGQPP 572
G L GAG P L A P LS G PPPS L Q P
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
Query: 573 PEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALG 632
E LPP PG P +P+GP+ L PPP + +P + LA L LG
Sbjct: 4332 TEAQLPPT-HPGTP----KPQGPT------LEPPPGRV-----SPAAAQLADTLFSKGLG 4375
Query: 633 P 633
P
Sbjct: 4376 P 4376
Score = 53.5 bits (127), Expect = 1e-06
Identities = 133/518 (25%), Positives = 174/518 (33%), Gaps = 82/518 (15%)
Query: 445 LSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKA-------PVVPSPVLQSPSE 497
LS Q + + P +P SS PGA P P V S + PS
Sbjct: 3985 LSPQQQQQQQVALGPGMPAKPLQHFSS-PGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
Query: 498 GLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
G PLA G +PE G P + G L L QP P P +
Sbjct: 4044 HQG---------GPLAIGT-----TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPS-S 4088
Query: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP 617
L L G Q LL GG + V LL P L P +
Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148
Query: 618 PSNLLASFLPLLALGPTAGDG-EGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIAL 676
NLL P+L G + G SG+ G+G + P + + ++A
Sbjct: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVG-IMPTVGQLRAQLQGVLAK 4207
Query: 677 NSALLAATLDPPSGTPPQPCVLS-------APQPGPPTSSVTTATTDPGASSLGKAPSNS 729
N L L P Q ++ A + PP T T+ P LG P
Sbjct: 4208 NPQL--RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS-PLQGLLGCQPQLG 4264
Query: 730 GRPPQLLSPL--LGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL 787
G P PL LGA P P L PPG L +G + L P PPP
Sbjct: 4265 GFPGPQTGPLQELGAG---------PRPQGPPRLPAPPGALSTGPV---LGPVHPTPPPS 4312
Query: 788 S--EASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPV 845
S E P S Q+P E LPP P + P+P P L PP G P
Sbjct: 4313 SPQEPKRPSQLPSPSSQLPTEAQ----LPPTHPGT---PKPQGPTLE---PPPGRVSPAA 4362
Query: 846 PEL---LTGRGSG--------------KRGRRGGGGLRGINGEARPARGR---KPGSRRE 885
+L L +G G ++ G L +NG+ P + K R E
Sbjct: 4363 AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
Query: 886 PGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG 923
P L + + NG+ +P ++H G +E G
Sbjct: 4423 PCALGAQ-SVKREANGEPIGAPGTSNHLLLAGPRSEAG 4459
Score = 47.8 bits (112), Expect = 5e-05
Identities = 187/835 (22%), Positives = 254/835 (30%), Gaps = 196/835 (23%)
Query: 133 QMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEP-PSVSQAFPTLAGPGGLFPPRLAD 191
Q V PP P + P L G L P P AGP PPRL
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 192 PVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHAS 251
P P S+ P P P P+ P P PS + + L P+ G+P +
Sbjct: 4292 P-PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT 4350
Query: 252 SSPPS---DPPLFHCSDALTPP---PLPPSNNLPAHPGP--------------------A 285
PP P +D L P P +NL P A
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEA 4410
Query: 286 SQPPVSSATMHLPLVLGPLGGAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPPPSTLQGR 344
SQ + P LG G P P ++ LL A +++ L L+ +
Sbjct: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
Query: 345 RPRAQAPSASH----------SSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPA- 393
+ S S L +++ + P+ R P TP+ R + +
Sbjct: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASD 4530
Query: 394 -----------------------PVPQPFSLPEPSQPILPSVLSLL-----GLPTPGPSH 425
+ Q SL ++P + + SL G P G S
Sbjct: 4531 RLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQ 4590
Query: 426 SDGSF------------NLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG--TTSGSLSS 471
G+F + L + +L PPT S PP P +Q + T S L
Sbjct: 4591 LRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGE 4650
Query: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGE--------------- 516
P A S+ L+ SE + A P PP E
Sbjct: 4651 HPKDAASARDSER------ALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDS 4704
Query: 517 AFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPL 576
P SPE L FP + P PL+ + V P +P
Sbjct: 4705 IVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVF------PDTKPY 4758
Query: 577 ----LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLP----- 627
L P G P + +G + V + + L + LL+ +P
Sbjct: 4759 GALGLEVP-GKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV 4817
Query: 628 LLALGPTAGDGE---GSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAAT 684
L P E G AEG GG GL S P + P L ++ L T
Sbjct: 4818 LFPESPARAGTEPKKGEAEGPGGKE----KGLEGKS-----PDTGPDWLKQFDAVLPGYT 4868
Query: 685 LDPPSGTPPQPCVLS-----APQPGPPTS-SVTTATTDPGASSLGKAPSNSGRPPQLLSP 738
L Q +LS +P P PPT S T ++ L S PP+ SP
Sbjct: 4869 L------KSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQL------SAPPPEEPSP 4916
Query: 739 LLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLL 798
PP PL AP P S + PL
Sbjct: 4917 -------------------------PPSPL--------------APSPASPPTEPL---- 4933
Query: 799 QSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRG 853
+++P E P +P P A PE ARP A P G P P L +G
Sbjct: 4934 --VELPTEPLAEPPVPSPLPL-ASSPESARPKPRARPPEEGEDSRP-PRLKKWKG 4984
Score = 35.4 bits (80), Expect = 0.27
Identities = 62/233 (26%), Positives = 81/233 (34%), Gaps = 46/233 (19%)
Query: 443 PTLSSGSPPQ--PRHPIQPSL--PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
P L + P Q P H +QP PG +G L PG A P P + + + Q +
Sbjct: 3625 PRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQ 3684
Query: 499 LGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML----------GALPLPLSLG 548
GAG LAG FP LAL G L + L L
Sbjct: 3685 HSGGAG------SLAGPSGGFFPG---NLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQ 3735
Query: 549 QPPPSPLLNHSLFGVLT-------GGGGQ------PPPEPLLPPPGGPG---PPLAPGEP 592
Q L G + G G Q P P+ L+PP G L+P P
Sbjct: 3736 QQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP 3795
Query: 593 EGPSLL-----VASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEG 640
+GP + VA L P L P P +L + +L+ A G+G
Sbjct: 3796 QGPQGMLGPAQVAVLQQQHPGAL--GPQGPHRQVLMTQSRVLSSPQLAQQGQG 3846
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 135 bits (339), Expect = 3e-31
Identities = 225/779 (28%), Positives = 267/779 (34%), Gaps = 150/779 (19%)
Query: 143 PSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPS-GGSSSP 201
P+AR P + P P GS P PP A L G + LA+ GG++ P
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 202 RFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF 261
PR + PP A PPA + S P S P
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERA--------------------PPAKNTSPGPVSSPG-- 109
Query: 262 HCSDALTPPPLPP-----SNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG--PG 314
S P PL S G A++ P SA G G PG
Sbjct: 110 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL--------SAGARRDTSGPTPG 161
Query: 315 APPFLASSLLSAAAKAQHPPLPPPSTL---QGRRPRAQAPSASHSSSLRPSQRRPRRP-- 369
P + AA P P PS PR SAS S+ PS RRP
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221
Query: 370 ------PTVFRLLEGRGP-QTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG 422
P L P +P RS P A P + PSQP P L L P
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARG---TPRAPAHPSQP-KPKGLQALRPPQVT 277
Query: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS 482
P D + L P + S + P P P PS P SL ++P PA P +
Sbjct: 278 PPRKDAAPAL--------GPLSSSPLATPSPSAPPSPSAP----PSLQTLPSPPATPPSQ 325
Query: 483 KAPVVPSPVLQS-----PSEGLG------MGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531
+ SP LQ+ PS L A PA LPPL + P P LA
Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 532 AGFPGMLGA--LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLA- 588
P L L P S PPPSP + PP P PP P LA
Sbjct: 386 PQAPNALAVHLLQAPFS---PPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAA 437
Query: 589 ------PGEPEGPSLLVASLLPP--------PPSDLL-PPPSAPPSNLLASFLPLLALGP 633
P P P + ++ PP PP L PPP APP+ + PL AL
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA---LATPPLQAL-- 492
Query: 634 TAGDGEGSAEGAGGPSGEPFSGLGDL--SPLLFPPLSAPPTLIALNSALLAATLDPPSGT 691
+ A P PFS L SPL PP APP L A LL PPS
Sbjct: 493 -------PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA---PLLQV---PPS-- 537
Query: 692 PPQPCVLSAPQPGPPTSSVTTATTDPG---ASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748
PP L AP+ PPT T+ + P A + G P S P LS G L G
Sbjct: 538 PPASPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS---GPDLAGHS 593
Query: 749 SSLTSSPGALPSLLQPP--GPLLSGQLGLQLLP------GGGAPPPLSEASSPLACLLQS 800
SS TS+P L P G S +L G PPL+ +P A L
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653
Query: 801 LQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGR 859
P + C E+ PE A P AL P SP + G G+G R
Sbjct: 654 PATGPGSADGLCTIYETEG----PESATPAPGAL-DPGPSPGTSGGKAAAGAGAGASSR 707
Score = 98.6 bits (244), Expect = 3e-20
Identities = 141/483 (29%), Positives = 179/483 (37%), Gaps = 84/483 (17%)
Query: 126 PGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG-- 183
P A+P T S G P+ + P+ PL+ P + PP + A P L P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPPPQAPPALALPPLQAPPSPP 373
Query: 184 LFPP--RLADPVPSGGSS------SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRS 235
PP LA P P ++ F P + P AP PPA +PS A
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-----ATPP 428
Query: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS--A 293
S P L +PP SPP+ PP+ S + TPPP P L A P ++PP + A
Sbjct: 429 SQAPPSLAAPPL-QVPPSPPASPPM---SPSATPPPQAPP-PLAAPPLQLAKPPPQAPPA 483
Query: 294 TMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSA 353
PL P +P PG PF S+ L + A PP PP P Q P +
Sbjct: 484 LATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPS 537
Query: 354 SHSSSLRPSQRRPRRPPTVFRLLEGRGPQT----PRRSRPRAPAPVPQPFSLPEPSQPIL 409
+S P+ + PRRPPT GP T PR + AP P P P P
Sbjct: 538 PPAS---PTLQAPRRPPT-------PGPDTSVSGPRLTLALAPGPPPPPSRSPS------ 581
Query: 410 PSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSL 469
S LS L S + L G D+ P + + P P + P S
Sbjct: 582 -STLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDAELAACHPAAWS--- 633
Query: 470 SSVPGAPAPPAASK-APVVPSPVLQSPSEGLGMG-------AGPACPLPPLAGGEAFPFP 521
PAPP A + AP P P + G G GP P + P P
Sbjct: 634 ----RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Query: 522 SPEQGLALSGAGF--------PGMLGALPLPLSLGQPPPSPLLNHSLF-----GVLTGGG 568
G A +GAG LG LPL +L LL+ +L G G G
Sbjct: 690 GTSGGKAAAGAGAGASSRSPKQARLGELPLG-ALQASVVQHLLSRTLLLAAAEGAAGGSG 748
Query: 569 GQP 571
G P
Sbjct: 749 GGP 751
Score = 44.3 bits (103), Expect = 6e-04
Identities = 70/271 (25%), Positives = 94/271 (34%), Gaps = 61/271 (22%)
Query: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809
+PG L P +PP P+ L + G PL+E + + IP P
Sbjct: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76
Query: 810 APCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSG--KRGRRGGGGLRG 867
A P ++ E A P + P SP GR SG + G G GLR
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSP---------GRASGTTRPGPLGQKGLR- 126
Query: 868 INGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPK 927
I+ E ARG+ + P R AL G R +G +P + E G
Sbjct: 127 ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL--- 180
Query: 928 DPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR-------- 979
P P P S R R P ++ +S+ + T EPSP AR
Sbjct: 181 --PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224
Query: 980 -----------AAVPLPPRARPGRPAKNKRR 999
+A PL AR G A+ R
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPR 255
Score = 30.8 bits (68), Expect = 6.7
Identities = 38/149 (25%), Positives = 50/149 (33%), Gaps = 12/149 (8%)
Query: 79 LAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTV 138
LAP P P+S L H A + R + S G ASP +
Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD---SGPEGGAAASPPPDAEL 624
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT-------LAGPGGLFP-PRLA 190
+ P+A PP G PG+ P PP+ GP P P
Sbjct: 625 AACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683
Query: 191 DPVPSGGSSSPRFLPRGNAPSPAPPPPPA 219
DP PS G+S + A + + P A
Sbjct: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQA 712
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 133 bits (335), Expect = 7e-31
Identities = 235/802 (29%), Positives = 275/802 (34%), Gaps = 157/802 (19%)
Query: 143 PSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPR 202
P+AR P + P P GS P PP A L G + LA+ G ++
Sbjct: 17 PAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-- 69
Query: 203 FLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFH 262
P AP P S S N A R +PPA + S P S P
Sbjct: 70 ------IPESAPRAGPTRSAGTSSRN--PASRPPASGRGERAPPAKNTSPGPVSSPG--R 119
Query: 263 CSDALTPPPLPP-----SNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG--PGA 315
S P PL S G A++ P SA G G PG
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL--------SAGARRDTSGPTPGT 171
Query: 316 PPFLASSLLSAAAKAQHPPLPPPSTL---QGRRPRAQAPSASHSSSLRPSQRRPRRP--- 369
P + AA P P PS PR SAS S+ PS RRP
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 370 -----PTVFRLLEGRGP-QTPRRS------RPRAPA----PVPQPFSLPEPSQPILP--- 410
P L P +P RS PRAPA P P+ P Q P
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 411 -----SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGS------PPQPRHPIQP 459
LS L TP PS + L S A P T S S P P P P
Sbjct: 292 AAPALGPLSSSPLATPSPSAA------LQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 460 SLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS-----PSEGLG------MGAGPACP 508
S P SL ++P PA P + + SP LQ+ PS L A PA
Sbjct: 346 SAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 509 LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA--LPLPLSLGQPPPSPLLNHSLFGVLTG 566
LPPL + P P LA P L L P S PPPSP +
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPPVQAPF-----S 453
Query: 567 GGGQPPPEPLLPPPGGPGPPLA-------PGEPEGPSLLVASLLPP--------PPSDLL 611
PP P PP P LA P P P + ++ PP PP L
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 612 -PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDL--SPLLFPPLS 668
PPP APP+ + PL AL + A P PFS L SPL PP
Sbjct: 514 KPPPQAPPA---LATPPLQAL---------PSPPASFPGQAPFSPSASLPMSPLATPPPQ 561
Query: 669 APPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPG---ASSLGKA 725
APP L A LL PPS PP L AP+ PPT T+ + P A + G
Sbjct: 562 APPVLAA---PLLQV---PPS--PPASPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 726 PSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPP--GPLLSGQLGLQLLP---- 779
P S P LS G L G SS TS+P L P G S +L
Sbjct: 613 PPPSRSPSSTLS---GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669
Query: 780 --GGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPP 837
G PPL+ +P A L P + C E+ PE A P AL P
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG----PESATPAPGAL-DP 724
Query: 838 HGSPDPPVPELLTGRGSGKRGR 859
SP + G G+G R
Sbjct: 725 GPSPGTSGGKAAAGAGAGASSR 746
Score = 98.6 bits (244), Expect = 3e-20
Identities = 141/483 (29%), Positives = 179/483 (37%), Gaps = 84/483 (17%)
Query: 126 PGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG-- 183
P A+P T S G P+ + P+ PL+ P + PP + A P L P
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPPPQAPPALALPPLQAPPSPP 412
Query: 184 LFPP--RLADPVPSGGSS------SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRS 235
PP LA P P ++ F P + P AP PPA +PS A
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-----ATPP 467
Query: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS--A 293
S P L +PP SPP+ PP+ S + TPPP P L A P ++PP + A
Sbjct: 468 SQAPPSLAAPPL-QVPPSPPASPPM---SPSATPPPQAPP-PLAAPPLQLAKPPPQAPPA 522
Query: 294 TMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSA 353
PL P +P PG PF S+ L + A PP PP P Q P +
Sbjct: 523 LATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPS 576
Query: 354 SHSSSLRPSQRRPRRPPTVFRLLEGRGPQT----PRRSRPRAPAPVPQPFSLPEPSQPIL 409
+S P+ + PRRPPT GP T PR + AP P P P P
Sbjct: 577 PPAS---PTLQAPRRPPT-------PGPDTSVSGPRLTLALAPGPPPPPSRSPS------ 620
Query: 410 PSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSL 469
S LS L S + L G D+ P + + P P + P S
Sbjct: 621 -STLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDAELAACHPAAWS--- 672
Query: 470 SSVPGAPAPPAASK-APVVPSPVLQSPSEGLGMG-------AGPACPLPPLAGGEAFPFP 521
PAPP A + AP P P + G G GP P + P P
Sbjct: 673 ----RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Query: 522 SPEQGLALSGAGF--------PGMLGALPLPLSLGQPPPSPLLNHSLF-----GVLTGGG 568
G A +GAG LG LPL +L LL+ +L G G G
Sbjct: 729 GTSGGKAAAGAGAGASSRSPKQARLGELPLG-ALQASVVQHLLSRTLLLAAAEGAAGGSG 787
Query: 569 GQP 571
G P
Sbjct: 788 GGP 790
Score = 48.9 bits (115), Expect = 2e-05
Identities = 74/274 (27%), Positives = 99/274 (36%), Gaps = 58/274 (21%)
Query: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809
+PG L P +PP P+ L + G PL+E + + IP P
Sbjct: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76
Query: 810 APCLPPESPASALEPEPARPPLSAL---APPHGSPDPPVPELLTGRGSG--KRGRRGGGG 864
A P S ++ +RPP S APP + P P GR SG + G G G
Sbjct: 77 AG--PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLGQKG 133
Query: 865 LRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGA 924
LR I+ E ARG+ + P R AL G R +G +P + E G
Sbjct: 134 LR-ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 925 EPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR----- 979
P P P S R R P ++ +S+ + T EPSP AR
Sbjct: 190 -----PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 980 --------------AAVPLPPRARPGRPAKNKRR 999
+A PL AR G A+ R
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Score = 39.7 bits (91), Expect = 0.014
Identities = 112/488 (22%), Positives = 151/488 (30%), Gaps = 108/488 (22%)
Query: 535 PGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPE- 593
PG+L P G P P P + + VL G G +PL GG G P
Sbjct: 22 PGLL----TPRPPGSPRPPPPVTPAALRVL-GAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 594 -GPSLLVASLLPPPPSDLLPPPS-----APPSNLLASFLPLLALGPTAGDGEGSAEGAGG 647
GP+ + P S PP S APP+ + GP + G S G
Sbjct: 77 AGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTSP-------GPVSSPGRASGTTRPG 127
Query: 648 PSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPT 707
P G+ + + + P AL++ T S P PG P+
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--------------SGPTPGTPS 173
Query: 708 SSVTTATTDPGASSLGKAPSNSGRP-PQLLSPLLGASLLGDLSSLTSSPGAL--PSLLQP 764
++ + G P+ S RP P P S + S+ SP A PS
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--- 230
Query: 765 PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEP 824
GGG P S + S A L S P + P +PA +P
Sbjct: 231 ---------------GGGLQRPASRSLSSSATPLSS---PARSGPSARGTPRAPAHPSQP 272
Query: 825 EPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRR 884
+P L AL PP +P +A PA G S
Sbjct: 273 KPKG--LQALRPPQVTPP--------------------------RKDAAPALGPLSSS-- 302
Query: 885 EPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHS----EDLK 940
T ++P H+ L A P PP P + + L
Sbjct: 303 -------PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 941 VPPGVVRKSRRGRRRKYNPTRNSNSS-----RQDITLEPSPTARAAVPLPP-RARPGRPA 994
PP + +PT + S P P A A+ LPP +A P PA
Sbjct: 356 SPPAT--PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 995 KNKRRKLA 1002
LA
Sbjct: 414 SPPLSPLA 421
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 819 ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLR-------GINGE 871
A+A P P L PP GSP PP P +T G G G + GI G
Sbjct: 12 AAARTPAARAPGLLTPRPP-GSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 872 ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG--AEPKDP 929
P + G R G + +R +G+ ER+P + G ++ G + P
Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN--TSPGPVSSPGRASGTTRP 126
Query: 930 PPPGPHSEDLKVPPGVVR-KSRRGRRRKYNPTRNSNSSRQDITLEPSPT----ARAA--- 981
P G + V R K+ +R + PSP +RAA
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 982 VPLP---PRARPGRPAKNKRRKLA 1002
V LP P ARP P + R+ ++
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVS 210
Score = 30.8 bits (68), Expect = 6.7
Identities = 38/149 (25%), Positives = 50/149 (33%), Gaps = 12/149 (8%)
Query: 79 LAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTV 138
LAP P P+S L H A + R + S G ASP +
Sbjct: 607 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD---SGPEGGAAASPPPDAEL 663
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT-------LAGPGGLFP-PRLA 190
+ P+A PP G PG+ P PP+ GP P P
Sbjct: 664 AACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722
Query: 191 DPVPSGGSSSPRFLPRGNAPSPAPPPPPA 219
DP PS G+S + A + + P A
Sbjct: 723 DPGPSPGTSGGKAAAGAGAGASSRSPKQA 751
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 124 bits (312), Expect = 3e-28
Identities = 238/863 (27%), Positives = 292/863 (33%), Gaps = 147/863 (17%)
Query: 126 PGEGASPQMFHTVSPGPPSAR--PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG 183
PG P + PGPP + P PP P G PG + E P FP GP G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP--GTPGRIGLEGPPGPPGFP---GPKG 749
Query: 184 LFPPRLADPVPSGGSSSPRFL----PRGNAPSPAPPPPPAIS----LNAPSYNWGAALRS 235
P A P P G P F P+G+ P PP PP + L P + G
Sbjct: 750 --EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG----P 803
Query: 236 SLVPSDLGSPPAPHAS-SSPPSDP--------PLFHCSDALTPPPLPPSNNLPAHPGPAS 286
+ P +G P P PP P P H P PP ++P PG
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 287 QPPVSSATMHLPLVLGPLG--GAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPP-PSTLQ 342
P + A GP+G G+P + G GA F + PP PP P +
Sbjct: 864 SPGIPGAP-------GPIGPPGSPGLPGKAGASGFPGT---KGEMGMMGPPGPPGPLGIP 913
Query: 343 GRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401
G R+ P L Q +P P PT + +G P P P P +
Sbjct: 914 G---RSGVPGLKGDDGL---QGQPGLPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEK 966
Query: 402 PEPSQPILPSV---LSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI 457
EP P +P V GLP PG G L G PP P + G P QP
Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG-----PPGPKGNPGLPGQPGLIG 1021
Query: 458 QPSLPGTTSG-SLSSVPGAPAPPAASKAPVVP-SPVLQSPSEGLGMGAGPACPLPPLAGG 515
P L GT G PP S P P SP L G + LP L G
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081
Query: 516 EAFP-FPSPEQGLALSGA-GFPGMLGALPLPLSLGQP--PPSPLLNHSLFGVLTGGGGQP 571
+ P P + G+ G PG+ G P + GQP P P G G P
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-----------GTPGPP 1130
Query: 572 PPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLAL 631
P+ + PPG PG P PG G P PP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGG--------------HPGQPGPP------------- 1163
Query: 632 GPTAGDGEGSAEGAGGPSGEPFS-GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSG 690
G G+ G G GEP G G+ P P LS L L P G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 691 TP---PQPCVLSAP-QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLG 746
P P V P PG P ++ +PG P G P P L + G
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGN--G 1281
Query: 747 DLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPE 806
+ +PG QP G GL L G PP L +P L ++ P
Sbjct: 1282 GIKGEKGNPG------QP------GLPGLPGLKGDQGPPGLQ--GNPGRPGLNGMKGDPG 1327
Query: 807 QPEAPCLP----PESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGG 862
P P P P + PE P L P G P P ++ +G G G
Sbjct: 1328 LPGVPGFPGMKGPSGVPGSAGPE-GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1386
Query: 863 GGLRGINGEARPARGRKP-GSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAE 921
GL+G+ G P P G +PGR L GF+G R G +
Sbjct: 1387 PGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP-----GFDGAGGRK-------GDPGLPGQ 1434
Query: 922 GGAEPKDPPPPGPHSEDLKVPPG 944
G D PPGP + L+ PPG
Sbjct: 1435 PGTRGLD-GPPGP--DGLQGPPG 1454
Score = 122 bits (305), Expect = 2e-27
Identities = 250/922 (27%), Positives = 299/922 (32%), Gaps = 141/922 (15%)
Query: 126 PG-EGASPQMFHTVSPGPPSA---RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181
PG +G Q T PGPP RP + N G LP E + FP + GP
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE--RGFPGIQGP 381
Query: 182 GGL-FPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
GL PP A P G P G PP IS+ P L
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFP-----GERGQKGDEGPPGISIPGPP-----GLDGQPGAP 431
Query: 241 DLGSPPAPHASSSPPSD---------PP---------------------LFHC--SDALT 268
L PP P PPSD PP F+C +
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491
Query: 269 PPPLPPSNNLPAHPG----PASQPPVSSATMHLPLVLGPLGGAPTVEG-PGAPPFLASSL 323
PP P LP PG P + A P L + GAP G PG+ L
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551
Query: 324 LSAAAKAQH--------PPLP--PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
K P LP P + Q P P +R P P +
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
L GP P P P PV + P P + PGP G
Sbjct: 612 GLPGNIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPGI--------PGPKGDPGQTITQ 661
Query: 434 GSDAHLPPPPTLSS--GSPPQPRHPIQPSLPGTT-SGSLSSVPGA--PAPPAASKAPVVP 488
LP P G P P P QP LPG S +PG P PP P +P
Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721
Query: 489 SPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGA----GFPGMLGALPLP 544
P + G GP P PP FP P E G AL G G PG GAL
Sbjct: 722 GPPGAPGTPGRIGLEGP--PGPP-----GFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 545 LSLGQP-PPSPLLNHSLFGVL-----TGGGGQPPP--EPLLPPPGGPGPPLAPGEPEGPS 596
G P PP P L G+ G GQP P P LP G GPP PG P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834
Query: 597 LLVASLLPPPPSDLLPPP---SAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPF 653
+P D PP PP + +P A GP G G G SG P
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG-APGPIGPPGSPGLPGKAGASGFPG 893
Query: 654 S----GL----GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPG 704
+ G+ G PL P S P L + L P+G P PG
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953
Query: 705 PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP 764
P ++ + + G L P SG P+ L G LS PG P
Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPGLSGQPGLPG-------P 1004
Query: 765 PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL-LQSLQIPPEQPEAPCLPPESPASALE 823
PGP G GL PG PP L + Q ++ PP P P +
Sbjct: 1005 PGP--KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062
Query: 824 PEPARPPLSALAPPHGSPDPPVPELLTGR--GSGKRGRRGGGGLRGINGEARPARGRKPG 881
+ P +S++ P G P P L G G +G G GL G+ G PG
Sbjct: 1063 GDKGDPGISSIGLP-GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT--------PG 1113
Query: 882 SRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG----PHSE 937
++ +PG GT G + P GG P P PPG P +
Sbjct: 1114 AKGQPGLPGFP-GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172
Query: 938 DLKVPPGVVRKSRRGRRRKYNP 959
+ P G +K G+ NP
Sbjct: 1173 GIPGPAG--QKGEPGQPGFGNP 1192
Score = 107 bits (267), Expect = 6e-23
Identities = 217/816 (26%), Positives = 266/816 (32%), Gaps = 132/816 (16%)
Query: 140 PGPPSARPPCRVP--PTTP-LNGGPG-SLPPEPPSV--------------SQAFPTLAGP 181
PGP R P +P P TP L G PG P P + S FP L GP
Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145
Query: 182 GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS-LNAPSYNWGAALRSSLVPS 240
G PP + GS LP G +P P PP I L P+ +P
Sbjct: 146 PG--PPGIPGMKGEPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTG----------IPG 192
Query: 241 DLGSPPAPHASSSPPSDPPLFHCSDALT-----PPPLPPSNNLPAHPGPASQPPVSSATM 295
+G PP P PP P L + P L PGP Q +
Sbjct: 193 PIG-PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH 355
+ G G P GP PP + P PP +G + P
Sbjct: 252 DVEFQKGDQG-LPGDRGPPGPPGIRG------------PPGPPGGEKGEKGEQGEPGKRG 298
Query: 356 SSSLRPSQRRPRRPPTVFRLLEGRG-PQTPRRSRPRAPA-----PVPQPFSLPEPSQPIL 409
+P + P + L G P P R + P P +P P I
Sbjct: 299 ----KPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354
Query: 410 PSVLSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGS 468
+GLP PG G + G PP G P P P + G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414
Query: 469 LSSVPGAPAPPAASKAPVVPSPVLQS-----PSEGLGMGAGPACPLPP----LAGGEAFP 519
S+PG P AP +P P + PS+ + P P P L G +
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474
Query: 520 FPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPP 579
+ G G G G LP G P P L G G P+ L
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLP---GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531
Query: 580 PGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP-----PSNLLASFLPLLALGPT 634
PG PG P PG P ++ L P AP P LP L GP
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-GPK 590
Query: 635 AGDGEGSAEGAGGPSGEP-FSGL-GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692
G + +G GP G P GL G++ P + PP PP + + +G P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGP-MGPPGFGPPGPVGEKG------IQGVAGNP 643
Query: 693 PQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGD--LSS 750
QP + PGP T T PG L P N GR + L GD L
Sbjct: 644 GQPGI-----PGPKGDPGQT-ITQPGKPGL---PGNPGRDGDV-------GLPGDPGLPG 687
Query: 751 LTSSPGALPSLLQP--PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQP 808
PG S +P PG L G G + PG PP + L+ PP P
Sbjct: 688 QPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPP 742
Query: 809 EAPCLPPESPASALEPEPARPPL----SALAP--PHGSPDPPVPELLTGRG--------- 853
P P P AL P P L AL P G P PP P TG
Sbjct: 743 GFPG-PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV 801
Query: 854 --SGKRGRRGGGGLRGINGEARPARGRKPGSRREPG 887
+G+ G G GL GI + P PG +PG
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837
Score = 103 bits (258), Expect = 6e-22
Identities = 284/1080 (26%), Positives = 336/1080 (31%), Gaps = 273/1080 (25%)
Query: 140 PGPPSAR---PPCRVPPTTPLNGG-------PGSLPPEPPSVS--QAFPTLAGPGGLFPP 187
PGPP A PP PP P G PG P PP + P L GP G P
Sbjct: 385 PGPPGAAVMGPPG--PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 188 RL------ADPVPSGGSSSPRFL--------------------------PRGNAPSPAPP 215
+ +P P G SP P G P P
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 216 PPPAISLNAPSYNWGAALRSSLVPSDL-GSPPAPHASSSPPSDPPLFHCSDALTPPPL-- 272
PP SL P + P L G P AP A P S D LT P +
Sbjct: 503 GPPG-SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG---EPGDILTFPGMKG 558
Query: 273 -------------------PPSNNLPAHPGPASQP-----------PVSSATMHLPLVLG 302
P + LP PGP +P P + LP +G
Sbjct: 559 DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618
Query: 303 PLG----------------------GAPTVEGPGAPPFLASSLLSAAAKAQHPP------ 334
P+G G P + GP P + +P
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678
Query: 335 LPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGR--GPQTPRR----- 386
LP L G+ P + + P P P P F + G P TP R
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGI-PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEG 737
Query: 387 --SRPRAPAPVPQP-FSLP-EPSQPILPSVLSLLGLPT----PGPSHSDGSFNLLGSDAH 438
P P P +P F+LP P P LP LG PGP G L G
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL--- 794
Query: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
P P G QP P LPG PG P P +P G
Sbjct: 795 --PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852
Query: 499 LGMGAGPA---CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQP-PPSP 554
L + P P P A G P SP +GFPG G + + +G P PP P
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---MGPPGPPGP 909
Query: 555 LLNHSLFGV--------LTGGGGQPPP--------EPLLPPPGGP------------GPP 586
L GV L G G P P EP LP P GP G P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 587 LAPGEPEGPSLLVASLLPPPPSDL-------LPPPSAPPSNLLASFLPLLALGP-----T 634
PG P LP P LP P P N P L +GP T
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGT 1028
Query: 635 AGD----GEGSAEGAGGPSGEP----FSGL----GD-----LSPLLFPPLSAPPTLIAL- 676
GD G EG GPSG P GL GD +S + P L P L
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088
Query: 677 ----NSALLAATLDPP-SGTPPQPCVLSAP-------QPGPPTSSVTTATT-------DP 717
N + + DP G P P P PGPP + +P
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148
Query: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ--PPG-PLLSGQLG 774
G G P G P + P G + + PG P PPG P LSGQ G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKP--GQDGIPGPAGQKGEPGQ-PGFGNPGPPGLPGLSGQKG 1205
Query: 775 LQLLPG----GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPE--PAR 828
LPG G P P E P +Q PP P +P E P P+ P R
Sbjct: 1206 DGGLPGIPGNPGLPGPKGE---PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262
Query: 829 PPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGR 888
P L P G P P + G G G+ G GL G+ G+ P PG + PGR
Sbjct: 1263 PGFQGLPGPEGPPGLPGNGGIKGE-KGNPGQPGLPGLPGLKGDQGP-----PGLQGNPGR 1316
Query: 889 LALKWGTRG--------GFNGQMERSPRRTHHWQHNGELAEGGAEPKDPP----PPGPHS 936
L G +G GF G S G A P+ P PPG
Sbjct: 1317 PGLN-GMKGDPGLPGVPGFPGMKGPSG------------VPGSAGPEGEPGLIGPPG--- 1360
Query: 937 EDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKN 996
PPG+ S + K + + + P P +P P PG P +N
Sbjct: 1361 -----PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP-GPTGPPGDPGRN 1414
Score = 99.8 bits (247), Expect = 1e-20
Identities = 227/869 (26%), Positives = 270/869 (31%), Gaps = 177/869 (20%)
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL--FPPRLADPVPSG 196
SPG P + P P + G PGS+ + P GP G+ P P P G
Sbjct: 136 SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAAL---RSSLVPSDLGSPPAPHASSS 253
P + PP PP L P N G + L PP P S
Sbjct: 196 PPGPPGLM--------GPPGPP--GLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245
Query: 254 PPSDP--PLFHCSDALTP----PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG-- 305
P F D P PP PP P PGP P G G
Sbjct: 246 EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKD 303
Query: 306 ---GAPTVEGPGAPPFLASSLLSAAAKAQH----PPLPP------PST------------ 340
G P + G P K Q PP PP P T
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363
Query: 341 --LQGRRPRAQAPSASHSSSL-RPSQRRPRRPPTVFRLLEGRGPQ----TPRRSRPRAPA 393
L G + P L P PP RG + P S P P
Sbjct: 364 PGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPG 423
Query: 394 PVPQPFS-----LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLG--------SDAHLP 440
QP + P P+ P +P + PGP S G L G D
Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483
Query: 441 PPPTLSSGSPPQPRHPIQPSLPG----------------TTSGSLSSVPGAPAPPAASKA 484
T SG P QP P P PG T L +PGAP P +
Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGS 543
Query: 485 PVVPSPVLQSP-----SEGLGMGAGPACP-LPPLAGGEAFP-FPSPE---QGLALSG--- 531
P +L P LG P P LP G + P P P+ G+ G
Sbjct: 544 KGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Query: 532 -------AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQP------------- 571
G PG +G + P G PP P+ + GV G GQP
Sbjct: 604 PPGNPGLPGLPGNIGPMGPP---GFGPPGPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659
Query: 572 --PPEPLLPPPGG-------PGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLL 622
P +P LP G PG P PG+P P + + P P LP P P
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG--- 716
Query: 623 ASFLPLLALGPTAGDGEGSAEGAGGPSGEP-FSGLGDLSPLLFPPLSAPPTLIALNSALL 681
P + GP G G GP G P F G P PP L AL
Sbjct: 717 ---FPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL- 771
Query: 682 AATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG--RPPQLLSPL 739
P G PGPP PG + L P G P P+
Sbjct: 772 -----GPKG--------DRGFPGPP--------GPPGRTGLDGLPGPKGDVGPNGQPGPM 810
Query: 740 LGASLLGDLSSLTSSPGALPSLLQPPG-PLLSGQLGLQLLPGGGAPPPLSEASSPLACLL 798
L G P +P + PG + G+ G PG P P E SP +
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP---GI 867
Query: 799 QSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRG 858
P P +P LP ++ AS P G P PP P + GR SG G
Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGF------PGTKGEMGMMGPPGPPGPLGIPGR-SGVPG 920
Query: 859 RRGGGGLRGINGEARPARGRKPGSRREPG 887
+G GL+G G P G K GS+ EPG
Sbjct: 921 LKGDDGLQGQPGLPGPT-GEK-GSKGEPG 947
Score = 76.6 bits (187), Expect = 1e-13
Identities = 158/590 (26%), Positives = 192/590 (32%), Gaps = 100/590 (16%)
Query: 417 GLPT-PGPSHSDGSFNLLGSDAHLPPP-PTLSSGSPPQPRHPIQPSLPGTT----SGSLS 470
GLP PGP G G D PP P G P P P P LPG +
Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQ 119
Query: 471 SVPGAPAPPAASKAPVVPS-PVLQSPSEGLGM-------GAGPACPLPPLAGGEAFPFPS 522
+PG P P P LQ P G+ G+ LP G +P P
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179
Query: 523 PEQGLALSGAGFPGMLGALPLPLSLGQPP-----PSPLLNHSLFGVLTGGGGQPPPEPLL 577
QGL G PG +G P P L PP P P N L G G+ + L
Sbjct: 180 GIQGLP-GPTGIPGPIGP-PGPPGLMGPPGPPGLPGPKGNMGL--NFQGPKGEKGEQGLQ 235
Query: 578 PPPGGPGP------PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP--PSNLLASFLPLL 629
PPG PG P+ +G L PP P + PP P
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295
Query: 630 ALGPTAGDGEGSAEGAGGPSGEP-FSG----------LGDLSPLLFPPLSAP----PTLI 674
G DGE G G G+P + G GD P P L P I
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDPGASSLGKAPSNSGRPP 733
+ L G P + P PGPP ++V PG + G P
Sbjct: 356 GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP- 414
Query: 734 QLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGG--APPPLSEAS 791
G S+ G L PGA P L PPGP G + P P P
Sbjct: 415 -------GISIPGP-PGLDGQPGA-PGLPGPPGP-----AGPHIPPSDEICEPGPPGPPG 460
Query: 792 SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTG 851
SP LQ Q C + + P +P L L P GS P +
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCF--NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK---- 514
Query: 852 RGSGKRGRRGGGGLRGING-EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRT 910
G++G+ G G +G+ G P PGS+ EPG + G +G
Sbjct: 515 ---GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKG------------- 558
Query: 911 HHWQHNGELAEGGAEPKDPPPPGPHSED--------LKVPPGVVRKSRRG 952
GEL GA P P PG +D P G+ K RG
Sbjct: 559 ----DKGELGSPGA-PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Score = 76.3 bits (186), Expect = 1e-13
Identities = 151/552 (27%), Positives = 183/552 (33%), Gaps = 84/552 (15%)
Query: 125 SPGEGASPQMFHTVSPGPPSARPPCRV------PPTTPLNGGPGSLPPEPPSVSQAFPTL 178
S GE P + PG P P P L+G PG P P + P
Sbjct: 962 SKGEKGEPGL-----PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP-- 1014
Query: 179 AGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL- 237
PG + PP L + G P+ + PS P P + L + G SS+
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074
Query: 238 ---VPSDLGSPPAPHASSSP--------PSDPPLFHCSDALTPPPLPPSNNLPAHPGPA- 285
+P G P P +P P P L A P LP P PGP
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134
Query: 286 -SQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLAS----SLLSAAAKAQHPPLP---- 336
S PP + LP GP+GG PG P + A + P P
Sbjct: 1135 ISGPPGNPG---LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191
Query: 337 --PPST--LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAP 392
PP L G++ P + P P+ P +GP P P +P
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGN----PGLPGPKGEPGFHGFPGVQGPPGP----PGSP 1243
Query: 393 APVPQ-PFSLPEPSQPILPSVLSLLGLPTP-GPSHSDGSFNLLGSDAH-----LPPPPTL 445
P + P P P P P GLP P GP G+ + G + LP P L
Sbjct: 1244 GPALEGPKGNPGPQGP--PGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301
Query: 446 SS--GSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL-GMG 502
G P +P +P L G +PG P P VP GL G
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDP--GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1359
Query: 503 AGPACPLPP----LAGGEAFPFPSPEQ-GLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
P P P + G+A P P Q GL G PG G LP G PP P N
Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTG-PPGDPGRN 1414
Query: 558 HSLFGVLTGGG--------GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSD 609
L G GG GQP L PPG G PG P G S + L S
Sbjct: 1415 -GLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG-PPGTSSVAHGFLITRHSQ 1472
Query: 610 LLPPPSAPPSNL 621
P P L
Sbjct: 1473 TTDAPQCPQGTL 1484
Score = 57.8 bits (138), Expect = 5e-08
Identities = 117/454 (25%), Positives = 146/454 (32%), Gaps = 101/454 (22%)
Query: 533 GFPGMLGALPLPLSLG-QPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGE 591
GFPG+ G LP G + PP P G+ G P P+ + PPG PG P PG
Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI----PGPPGPKGIRGPPGLPGFPGTPGL 106
Query: 592 PEGP-------------------------SLLVASLLPPPPSDLLPPPSAPPSNLLASFL 626
P P S L PP +P P +++ S L
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166
Query: 627 PLLALGPTAG---DGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683
P GP G +G GP+G P G + P P L PP
Sbjct: 167 P----GPKGNPGYPGPPGIQGLPGPTGIP----GPIGPPGPPGLMGPP------------ 206
Query: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGAS 743
P G P + GP + G L P G+ + P+
Sbjct: 207 ---GPPGLPGPKGNMGLNFQGP--------KGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255
Query: 744 LLGD--LSSLTSSPGALPSLLQPPGPL--LSGQLGLQLLPGGGAPPPLSEASSPLACLLQ 799
GD L PG P + PPGP G+ G Q PG P +
Sbjct: 256 QKGDQGLPGDRGPPGP-PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG------- 307
Query: 800 SLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP---VPELLTGRGSGK 856
QP P LP + EP R G P PP +P TG G+
Sbjct: 308 -------QPGIPGLPGD---PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 357
Query: 857 RGRRGGGGLRGINGE-ARPARGRKPGSRREPGRLALKWGTRGGFNGQM----ERSPRRTH 911
+G G GL G GE P PG PG + GF G+ + P
Sbjct: 358 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417
Query: 912 HWQHNGELAEGGAE--PKDPPPPGPHSEDLKVPP 943
G + GA P P P GPH +PP
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPH-----IPP 446
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 123 bits (309), Expect = 8e-28
Identities = 235/821 (28%), Positives = 286/821 (34%), Gaps = 127/821 (15%)
Query: 126 PGEGASPQMFHTVSPGPPSAR--PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG 183
PG P + PGPP + P PP P G PG + E P FP GP G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP--GTPGRIGLEGPPGPPGFP---GPKG 749
Query: 184 LFPPRLADPVPSGGSSSPRFL----PRGNAPSPAPPPPPAIS----LNAPSYNWGAALRS 235
P A P P G P F P+G+ P PP PP + L P + G
Sbjct: 750 --EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG----P 803
Query: 236 SLVPSDLGSPPAPHAS-SSPPSDP--------PLFHCSDALTPPPLPPSNNLPAHPGPAS 286
+ P +G P P PP P P H P PP ++P PG
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 287 QPPVSSATMHLPLVLGPLG--GAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPP-PSTLQ 342
P + A GP+G G+P + G GA F + PP PP P +
Sbjct: 864 SPGIPGAP-------GPIGPPGSPGLPGKAGASGFPGT---KGEMGMMGPPGPPGPLGIP 913
Query: 343 GRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401
G R+ P L Q +P P PT + +G P P P P +
Sbjct: 914 G---RSGVPGLKGDDGL---QGQPGLPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEK 966
Query: 402 PEPSQPILPSV---LSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI 457
EP P +P V GLP PG G L G PP P + G P QP
Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG-----PPGPKGNPGLPGQPGLIG 1021
Query: 458 QPSLPGTTSG-SLSSVPGAPAPPAASKAPVVP-SPVLQSPSEGLGMGAGPACPLPPLAGG 515
P L GT G PP S P P SP L G + LP L G
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081
Query: 516 EAFP-FPSPEQGLALSGA-GFPGMLGALPLPLSLGQP--PPSPLLNHSLFGVLTGGGGQP 571
+ P P + G+ G PG+ G P + GQP P P G G P
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-----------GTPGPP 1130
Query: 572 PPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP-----PPSDLLPPPSA----PPSNLL 622
P+ + PPG PG P PG P G PP P D +P P+ P
Sbjct: 1131 GPKGISGPPGNPGLPGEPG-PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189
Query: 623 ASFLPLLALGPTAGDGEGSA------EGAGGPSGEP-FSGLGDLSPLLFPPLSAPPTLIA 675
+ P G + G+G G GP GEP F G + PP S P
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP---- 1245
Query: 676 LNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQL 735
L+ P G P PQ P T PG P N G +
Sbjct: 1246 --------ALEGPKGNP-------GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEK 1290
Query: 736 LSPLLGASLLGDLSSLTSSPGALPSLLQPPG-PLLSGQLGLQLLPG-GGAPPPLSEASSP 793
+P G L L L G P L PG P L+G G LPG G P + P
Sbjct: 1291 GNP--GQPGLPGLPGLKGDQGP-PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP 1347
Query: 794 LACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPP-LSALAPPHGSPDPPVPELLTGR 852
+ + P P LP S S + A PP + G P P P+ L G
Sbjct: 1348 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG- 1406
Query: 853 GSGKRGRRGGGGLRGINGEARPARGRK--PGSRREPGRLAL 891
+G G G GL G +G A GRK PG +PG L
Sbjct: 1407 PTGPPGDPGRNGLPGFDG----AGGRKGDPGLPGQPGTRGL 1443
Score = 122 bits (305), Expect = 2e-27
Identities = 250/922 (27%), Positives = 299/922 (32%), Gaps = 141/922 (15%)
Query: 126 PG-EGASPQMFHTVSPGPPSA---RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181
PG +G Q T PGPP RP + N G LP E + FP + GP
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE--RGFPGIQGP 381
Query: 182 GGL-FPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
GL PP A P G P G PP IS+ P L
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFP-----GERGQKGDEGPPGISIPGPP-----GLDGQPGAP 431
Query: 241 DLGSPPAPHASSSPPSD---------PP---------------------LFHC--SDALT 268
L PP P PPSD PP F+C +
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491
Query: 269 PPPLPPSNNLPAHPG----PASQPPVSSATMHLPLVLGPLGGAPTVEG-PGAPPFLASSL 323
PP P LP PG P + A P L + GAP G PG+ L
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551
Query: 324 LSAAAKAQH--------PPLP--PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
K P LP P + Q P P +R P P +
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
L GP P P P PV + P P + PGP G
Sbjct: 612 GLPGNIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPGI--------PGPKGDPGQTITQ 661
Query: 434 GSDAHLPPPPTLSS--GSPPQPRHPIQPSLPGTT-SGSLSSVPGA--PAPPAASKAPVVP 488
LP P G P P P QP LPG S +PG P PP P +P
Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721
Query: 489 SPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGA----GFPGMLGALPLP 544
P + G GP P PP FP P E G AL G G PG GAL
Sbjct: 722 GPPGAPGTPGRIGLEGP--PGPP-----GFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 545 LSLGQP-PPSPLLNHSLFGVL-----TGGGGQPPP--EPLLPPPGGPGPPLAPGEPEGPS 596
G P PP P L G+ G GQP P P LP G GPP PG P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834
Query: 597 LLVASLLPPPPSDLLPPP---SAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPF 653
+P D PP PP + +P A GP G G G SG P
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG-APGPIGPPGSPGLPGKAGASGFPG 893
Query: 654 S----GL----GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPG 704
+ G+ G PL P S P L + L P+G P PG
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953
Query: 705 PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP 764
P ++ + + G L P SG P+ L G LS PG P
Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPGLSGQPGLPG-------P 1004
Query: 765 PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL-LQSLQIPPEQPEAPCLPPESPASALE 823
PGP G GL PG PP L + Q ++ PP P P +
Sbjct: 1005 PGP--KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062
Query: 824 PEPARPPLSALAPPHGSPDPPVPELLTGR--GSGKRGRRGGGGLRGINGEARPARGRKPG 881
+ P +S++ P G P P L G G +G G GL G+ G PG
Sbjct: 1063 GDKGDPGISSIGLP-GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT--------PG 1113
Query: 882 SRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG----PHSE 937
++ +PG GT G + P GG P P PPG P +
Sbjct: 1114 AKGQPGLPGFP-GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172
Query: 938 DLKVPPGVVRKSRRGRRRKYNP 959
+ P G +K G+ NP
Sbjct: 1173 GIPGPAG--QKGEPGQPGFGNP 1192
Score = 107 bits (267), Expect = 6e-23
Identities = 217/816 (26%), Positives = 266/816 (32%), Gaps = 132/816 (16%)
Query: 140 PGPPSARPPCRVP--PTTP-LNGGPG-SLPPEPPSV--------------SQAFPTLAGP 181
PGP R P +P P TP L G PG P P + S FP L GP
Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145
Query: 182 GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS-LNAPSYNWGAALRSSLVPS 240
G PP + GS LP G +P P PP I L P+ +P
Sbjct: 146 PG--PPGIPGMKGEPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTG----------IPG 192
Query: 241 DLGSPPAPHASSSPPSDPPLFHCSDALT-----PPPLPPSNNLPAHPGPASQPPVSSATM 295
+G PP P PP P L + P L PGP Q +
Sbjct: 193 PIG-PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH 355
+ G G P GP PP + P PP +G + P
Sbjct: 252 DVEFQKGDQG-LPGDRGPPGPPGIRG------------PPGPPGGEKGEKGEQGEPGKRG 298
Query: 356 SSSLRPSQRRPRRPPTVFRLLEGRG-PQTPRRSRPRAPA-----PVPQPFSLPEPSQPIL 409
+P + P + L G P P R + P P +P P I
Sbjct: 299 ----KPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354
Query: 410 PSVLSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGS 468
+GLP PG G + G PP G P P P + G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414
Query: 469 LSSVPGAPAPPAASKAPVVPSPVLQS-----PSEGLGMGAGPACPLPP----LAGGEAFP 519
S+PG P AP +P P + PS+ + P P P L G +
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474
Query: 520 FPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPP 579
+ G G G G LP G P P L G G P+ L
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLP---GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531
Query: 580 PGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP-----PSNLLASFLPLLALGPT 634
PG PG P PG P ++ L P AP P LP L GP
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-GPK 590
Query: 635 AGDGEGSAEGAGGPSGEP-FSGL-GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692
G + +G GP G P GL G++ P + PP PP + + +G P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGP-MGPPGFGPPGPVGEKG------IQGVAGNP 643
Query: 693 PQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGD--LSS 750
QP + PGP T T PG L P N GR + L GD L
Sbjct: 644 GQPGI-----PGPKGDPGQT-ITQPGKPGL---PGNPGRDGDV-------GLPGDPGLPG 687
Query: 751 LTSSPGALPSLLQP--PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQP 808
PG S +P PG L G G + PG PP + L+ PP P
Sbjct: 688 QPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPP 742
Query: 809 EAPCLPPESPASALEPEPARPPL----SALAP--PHGSPDPPVPELLTGRG--------- 853
P P P AL P P L AL P G P PP P TG
Sbjct: 743 GFPG-PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV 801
Query: 854 --SGKRGRRGGGGLRGINGEARPARGRKPGSRREPG 887
+G+ G G GL GI + P PG +PG
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837
Score = 100 bits (249), Expect = 7e-21
Identities = 285/1085 (26%), Positives = 337/1085 (31%), Gaps = 280/1085 (25%)
Query: 140 PGPPSAR---PPCRVPPTTPLNGG-------PGSLPPEPPSVS--QAFPTLAGPGGLFPP 187
PGPP A PP PP P G PG P PP + P L GP G P
Sbjct: 385 PGPPGAAVMGPPG--PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 188 RL------ADPVPSGGSSSPRFL--------------------------PRGNAPSPAPP 215
+ +P P G SP P G P P
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 216 PPPAISLNAPSYNWGAALRSSLVPSDL-GSPPAPHASSSPPSDPPLFHCSDALTPPPL-- 272
PP SL P + P L G P AP A P S D LT P +
Sbjct: 503 GPPG-SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG---EPGDILTFPGMKG 558
Query: 273 -------------------PPSNNLPAHPGPASQP-----------PVSSATMHLPLVLG 302
P + LP PGP +P P + LP +G
Sbjct: 559 DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618
Query: 303 PLG----------------------GAPTVEGPGAPPFLASSLLSAAAKAQHPP------ 334
P+G G P + GP P + +P
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678
Query: 335 LPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGR--GPQTPRR----- 386
LP L G+ P + + P P P P F + G P TP R
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGI-PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEG 737
Query: 387 --SRPRAPAPVPQP-FSLP-EPSQPILPSVLSLLGLPT----PGPSHSDGSFNLLGSDAH 438
P P P +P F+LP P P LP LG PGP G L G
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL--- 794
Query: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
P P G QP P LPG PG P P +P G
Sbjct: 795 --PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852
Query: 499 LGMGAGPA---CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQP-PPSP 554
L + P P P A G P SP +GFPG G + + +G P PP P
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---MGPPGPPGP 909
Query: 555 LLNHSLFGV--------LTGGGGQPPP--------EPLLPPPGGP------------GPP 586
L GV L G G P P EP LP P GP G P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 587 LAPGEPEGPSLLVASLLPPPPSDL-------LPPPSAPPSNLLASFLPLLALGP-----T 634
PG P LP P LP P P N P L +GP T
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGT 1028
Query: 635 AGD----GEGSAEGAGGPSGEP----FSGL----GD-----LSPLLFPPLSAPPTLIAL- 676
GD G EG GPSG P GL GD +S + P L P L
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088
Query: 677 ----NSALLAATLDPP-SGTPPQPCVLSAP-------QPGPPTSSVTTATT-------DP 717
N + + DP G P P P PGPP + +P
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148
Query: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ--PPG-PLLSGQLG 774
G G P G P + P G + + PG P PPG P LSGQ G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKP--GQDGIPGPAGQKGEPGQ-PGFGNPGPPGLPGLSGQKG 1205
Query: 775 LQLLPG----GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPE--PAR 828
LPG G P P E P +Q PP P +P E P P+ P R
Sbjct: 1206 DGGLPGIPGNPGLPGPKGE---PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262
Query: 829 PPLSALAPPHGSPDPPVPELLTGRG-----SGKRGRRGGGGLRGINGEARPARGRKPGSR 883
P + G P P P L G G G G+ G GL G+ G+ P PG +
Sbjct: 1263 PGPTGF---QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP-----PGLQ 1314
Query: 884 REPGRLALKWGTRG--------GFNGQMERSPRRTHHWQHNGELAEGGAEPKDPP----P 931
PGR L G +G GF G S G A P+ P P
Sbjct: 1315 GNPGRPGLN-GMKGDPGLPGVPGFPGMKGPSG------------VPGSAGPEGEPGLIGP 1361
Query: 932 PGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPG 991
PG PPG+ S + K + + + P P +P P PG
Sbjct: 1362 PG--------PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP-GPTGPPG 1412
Query: 992 RPAKN 996
P +N
Sbjct: 1413 DPGRN 1417
Score = 99.8 bits (247), Expect = 1e-20
Identities = 227/869 (26%), Positives = 270/869 (31%), Gaps = 177/869 (20%)
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL--FPPRLADPVPSG 196
SPG P + P P + G PGS+ + P GP G+ P P P G
Sbjct: 136 SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAAL---RSSLVPSDLGSPPAPHASSS 253
P + PP PP L P N G + L PP P S
Sbjct: 196 PPGPPGLM--------GPPGPP--GLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245
Query: 254 PPSDP--PLFHCSDALTP----PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG-- 305
P F D P PP PP P PGP P G G
Sbjct: 246 EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKD 303
Query: 306 ---GAPTVEGPGAPPFLASSLLSAAAKAQH----PPLPP------PST------------ 340
G P + G P K Q PP PP P T
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363
Query: 341 --LQGRRPRAQAPSASHSSSL-RPSQRRPRRPPTVFRLLEGRGPQ----TPRRSRPRAPA 393
L G + P L P PP RG + P S P P
Sbjct: 364 PGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPG 423
Query: 394 PVPQPFS-----LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLG--------SDAHLP 440
QP + P P+ P +P + PGP S G L G D
Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483
Query: 441 PPPTLSSGSPPQPRHPIQPSLPG----------------TTSGSLSSVPGAPAPPAASKA 484
T SG P QP P P PG T L +PGAP P +
Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGS 543
Query: 485 PVVPSPVLQSP-----SEGLGMGAGPACP-LPPLAGGEAFP-FPSPE---QGLALSG--- 531
P +L P LG P P LP G + P P P+ G+ G
Sbjct: 544 KGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Query: 532 -------AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQP------------- 571
G PG +G + P G PP P+ + GV G GQP
Sbjct: 604 PPGNPGLPGLPGNIGPMGPP---GFGPPGPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659
Query: 572 --PPEPLLPPPGG-------PGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLL 622
P +P LP G PG P PG+P P + + P P LP P P
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG--- 716
Query: 623 ASFLPLLALGPTAGDGEGSAEGAGGPSGEP-FSGLGDLSPLLFPPLSAPPTLIALNSALL 681
P + GP G G GP G P F G P PP L AL
Sbjct: 717 ---FPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL- 771
Query: 682 AATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG--RPPQLLSPL 739
P G PGPP PG + L P G P P+
Sbjct: 772 -----GPKG--------DRGFPGPP--------GPPGRTGLDGLPGPKGDVGPNGQPGPM 810
Query: 740 LGASLLGDLSSLTSSPGALPSLLQPPG-PLLSGQLGLQLLPGGGAPPPLSEASSPLACLL 798
L G P +P + PG + G+ G PG P P E SP +
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP---GI 867
Query: 799 QSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRG 858
P P +P LP ++ AS P G P PP P + GR SG G
Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGF------PGTKGEMGMMGPPGPPGPLGIPGR-SGVPG 920
Query: 859 RRGGGGLRGINGEARPARGRKPGSRREPG 887
+G GL+G G P G K GS+ EPG
Sbjct: 921 LKGDDGLQGQPGLPGPT-GEK-GSKGEPG 947
Score = 76.6 bits (187), Expect = 1e-13
Identities = 158/590 (26%), Positives = 192/590 (32%), Gaps = 100/590 (16%)
Query: 417 GLPT-PGPSHSDGSFNLLGSDAHLPPP-PTLSSGSPPQPRHPIQPSLPGTT----SGSLS 470
GLP PGP G G D PP P G P P P P LPG +
Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQ 119
Query: 471 SVPGAPAPPAASKAPVVPS-PVLQSPSEGLGM-------GAGPACPLPPLAGGEAFPFPS 522
+PG P P P LQ P G+ G+ LP G +P P
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179
Query: 523 PEQGLALSGAGFPGMLGALPLPLSLGQPP-----PSPLLNHSLFGVLTGGGGQPPPEPLL 577
QGL G PG +G P P L PP P P N L G G+ + L
Sbjct: 180 GIQGLP-GPTGIPGPIGP-PGPPGLMGPPGPPGLPGPKGNMGL--NFQGPKGEKGEQGLQ 235
Query: 578 PPPGGPGP------PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP--PSNLLASFLPLL 629
PPG PG P+ +G L PP P + PP P
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295
Query: 630 ALGPTAGDGEGSAEGAGGPSGEP-FSG----------LGDLSPLLFPPLSAP----PTLI 674
G DGE G G G+P + G GD P P L P I
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDPGASSLGKAPSNSGRPP 733
+ L G P + P PGPP ++V PG + G P
Sbjct: 356 GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP- 414
Query: 734 QLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGG--APPPLSEAS 791
G S+ G L PGA P L PPGP G + P P P
Sbjct: 415 -------GISIPGP-PGLDGQPGA-PGLPGPPGP-----AGPHIPPSDEICEPGPPGPPG 460
Query: 792 SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTG 851
SP LQ Q C + + P +P L L P GS P +
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCF--NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK---- 514
Query: 852 RGSGKRGRRGGGGLRGING-EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRT 910
G++G+ G G +G+ G P PGS+ EPG + G +G
Sbjct: 515 ---GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKG------------- 558
Query: 911 HHWQHNGELAEGGAEPKDPPPPGPHSED--------LKVPPGVVRKSRRG 952
GEL GA P P PG +D P G+ K RG
Sbjct: 559 ----DKGELGSPGA-PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Score = 75.9 bits (185), Expect = 2e-13
Identities = 151/553 (27%), Positives = 183/553 (33%), Gaps = 83/553 (15%)
Query: 125 SPGEGASPQMFHTVSPGPPSARPPCRV------PPTTPLNGGPGSLPPEPPSVSQAFPTL 178
S GE P + PG P P P L+G PG P P + P
Sbjct: 962 SKGEKGEPGL-----PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP-- 1014
Query: 179 AGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL- 237
PG + PP L + G P+ + PS P P + L + G SS+
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074
Query: 238 ---VPSDLGSPPAPHASSSP--------PSDPPLFHCSDALTPPPLPPSNNLPAHPGPA- 285
+P G P P +P P P L A P LP P PGP
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134
Query: 286 -SQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLAS----SLLSAAAKAQHPPLP---- 336
S PP + LP GP+GG PG P + A + P P
Sbjct: 1135 ISGPPGNPG---LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191
Query: 337 --PPST--LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAP 392
PP L G++ P + P P+ P +GP P P +P
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGN----PGLPGPKGEPGFHGFPGVQGPPGP----PGSP 1243
Query: 393 APVPQ-PFSLPEPSQPI-LPSVLSLLGLPTP-GPSHSDGSFNLLGSDAH-----LPPPPT 444
P + P P P P P GLP P GP G+ + G + LP P
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303
Query: 445 LSS--GSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL-GM 501
L G P +P +P L G +PG P P VP GL G
Sbjct: 1304 LKGDQGPPGLQGNPGRPGLNGMKGDP--GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1361
Query: 502 GAGPACPLPP----LAGGEAFPFPSPEQ-GLALSGAGFPGMLGALPLPLSLGQPPPSPLL 556
P P P + G+A P P Q GL G PG G LP G PP P
Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK----GLPGPQGPQGLPGPTG-PPGDPGR 1416
Query: 557 NHSLFGVLTGGG--------GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPS 608
N L G GG GQP L PPG G PG P G S + L S
Sbjct: 1417 N-GLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG-PPGTSSVAHGFLITRHS 1474
Query: 609 DLLPPPSAPPSNL 621
P P L
Sbjct: 1475 QTTDAPQCPQGTL 1487
Score = 57.8 bits (138), Expect = 5e-08
Identities = 117/454 (25%), Positives = 146/454 (32%), Gaps = 101/454 (22%)
Query: 533 GFPGMLGALPLPLSLG-QPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGE 591
GFPG+ G LP G + PP P G+ G P P+ + PPG PG P PG
Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI----PGPPGPKGIRGPPGLPGFPGTPGL 106
Query: 592 PEGP-------------------------SLLVASLLPPPPSDLLPPPSAPPSNLLASFL 626
P P S L PP +P P +++ S L
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166
Query: 627 PLLALGPTAG---DGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683
P GP G +G GP+G P G + P P L PP
Sbjct: 167 P----GPKGNPGYPGPPGIQGLPGPTGIP----GPIGPPGPPGLMGPP------------ 206
Query: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGAS 743
P G P + GP + G L P G+ + P+
Sbjct: 207 ---GPPGLPGPKGNMGLNFQGP--------KGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255
Query: 744 LLGD--LSSLTSSPGALPSLLQPPGPL--LSGQLGLQLLPGGGAPPPLSEASSPLACLLQ 799
GD L PG P + PPGP G+ G Q PG P +
Sbjct: 256 QKGDQGLPGDRGPPGP-PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG------- 307
Query: 800 SLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP---VPELLTGRGSGK 856
QP P LP + EP R G P PP +P TG G+
Sbjct: 308 -------QPGIPGLPGD---PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 357
Query: 857 RGRRGGGGLRGINGE-ARPARGRKPGSRREPGRLALKWGTRGGFNGQM----ERSPRRTH 911
+G G GL G GE P PG PG + GF G+ + P
Sbjct: 358 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417
Query: 912 HWQHNGELAEGGAE--PKDPPPPGPHSEDLKVPP 943
G + GA P P P GPH +PP
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPH-----IPP 446
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 122 bits (307), Expect = 1e-27
Identities = 233/827 (28%), Positives = 282/827 (34%), Gaps = 145/827 (17%)
Query: 126 PGEGASPQMFHTVSPGPPSAR--PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG 183
PG P + PGPP + P PP P G PG + E P FP GP G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP--GTPGRIGLEGPPGPPGFP---GPKG 749
Query: 184 LFPPRLADPVPSGGSSSPRFL----PRGNAPSPAPPPPPAIS----LNAPSYNWGAALRS 235
P A P P G P F P+G+ P PP PP + L P + G
Sbjct: 750 --EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG----P 803
Query: 236 SLVPSDLGSPPAPHAS-SSPPSDP--------PLFHCSDALTPPPLPPSNNLPAHPGPAS 286
+ P +G P P PP P P H P PP ++P PG
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 287 QPPVSSATMHLPLVLGPLG--GAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPP-PSTLQ 342
P + A GP+G G+P + G GA F + PP PP P +
Sbjct: 864 SPGIPGAP-------GPIGPPGSPGLPGKAGASGFPGT---KGEMGMMGPPGPPGPLGIP 913
Query: 343 GRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401
G R+ P L Q +P P PT + +G P P P P +
Sbjct: 914 G---RSGVPGLKGDDGL---QGQPGLPGPTGEKGSKGE-PGLPGPPGPMDPNLLGSKGEK 966
Query: 402 PEPSQPILPSV---LSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI 457
EP P +P V GLP PG G L G PP P + G P QP
Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG-----PPGPKGNPGLPGQPGLIG 1021
Query: 458 QPSLPGTTSG-SLSSVPGAPAPPAASKAPVVP-SPVLQSPSEGLGMGAGPACPLPPLAGG 515
P L GT G PP S P P SP L G + LP L G
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081
Query: 516 EAFP-FPSPEQGLALSGA-GFPGMLGALPLPLSLGQP--PPSPLLNHSLFGVLTGGGGQP 571
+ P P + G+ G PG+ G P + GQP P P G G P
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-----------GTPGPP 1130
Query: 572 PPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP-----PPSDLLPPPSA----PPSNLL 622
P+ + PPG PG P PG P G PP P D +P P+ P
Sbjct: 1131 GPKGISGPPGNPGLPGEPG-PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189
Query: 623 ASFLPLLALGPTAGDGEGSA------EGAGGPSGEP-FSGLGDLSPLLFPPLSAPPTLIA 675
+ P G + G+G G GP GEP F G + PP S P
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP---- 1245
Query: 676 LNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQL 735
L+ P G P PQ P + PG G G P Q
Sbjct: 1246 --------ALEGPKGNP-------GPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQP 1290
Query: 736 LSPLLGASLLGDLS--SLTSSPG--ALPSLLQPPG----PLLSGQLGLQLLPGGGAPPPL 787
P L L GD L +PG L + PG P G G +PG P
Sbjct: 1291 GLPGL-PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1349
Query: 788 SEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPP-LSALAPPHGSPDPPVP 846
P P P LP S S + A PP + G P P P
Sbjct: 1350 PGLIGP--------------PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP 1395
Query: 847 ELLTGRGSGKRGRRGGGGLRGINGEARPARGRK--PGSRREPGRLAL 891
+ L G +G G G GL G +G A GRK PG +PG L
Sbjct: 1396 QGLPG-PTGPPGDPGRNGLPGFDG----AGGRKGDPGLPGQPGTRGL 1437
Score = 122 bits (305), Expect = 2e-27
Identities = 250/922 (27%), Positives = 299/922 (32%), Gaps = 141/922 (15%)
Query: 126 PG-EGASPQMFHTVSPGPPSA---RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181
PG +G Q T PGPP RP + N G LP E + FP + GP
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE--RGFPGIQGP 381
Query: 182 GGL-FPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
GL PP A P G P G PP IS+ P L
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFP-----GERGQKGDEGPPGISIPGPP-----GLDGQPGAP 431
Query: 241 DLGSPPAPHASSSPPSD---------PP---------------------LFHC--SDALT 268
L PP P PPSD PP F+C +
Sbjct: 432 GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491
Query: 269 PPPLPPSNNLPAHPG----PASQPPVSSATMHLPLVLGPLGGAPTVEG-PGAPPFLASSL 323
PP P LP PG P + A P L + GAP G PG+ L
Sbjct: 492 PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551
Query: 324 LSAAAKAQH--------PPLP--PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
K P LP P + Q P P +R P P +
Sbjct: 552 TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
L GP P P P PV + P P + PGP G
Sbjct: 612 GLPGNIGPMGPPGFGP--PGPVGEKGIQGVAGNPGQPGI--------PGPKGDPGQTITQ 661
Query: 434 GSDAHLPPPPTLSS--GSPPQPRHPIQPSLPGTT-SGSLSSVPGA--PAPPAASKAPVVP 488
LP P G P P P QP LPG S +PG P PP P +P
Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721
Query: 489 SPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGA----GFPGMLGALPLP 544
P + G GP P PP FP P E G AL G G PG GAL
Sbjct: 722 GPPGAPGTPGRIGLEGP--PGPP-----GFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 545 LSLGQP-PPSPLLNHSLFGVL-----TGGGGQPPP--EPLLPPPGGPGPPLAPGEPEGPS 596
G P PP P L G+ G GQP P P LP G GPP PG P
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834
Query: 597 LLVASLLPPPPSDLLPPP---SAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPF 653
+P D PP PP + +P A GP G G G SG P
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG-APGPIGPPGSPGLPGKAGASGFPG 893
Query: 654 S----GL----GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPG 704
+ G+ G PL P S P L + L P+G P PG
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953
Query: 705 PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP 764
P ++ + + G L P SG P+ L G LS PG P
Sbjct: 954 PMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPGLSGQPGLPG-------P 1004
Query: 765 PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL-LQSLQIPPEQPEAPCLPPESPASALE 823
PGP G GL PG PP L + Q ++ PP P P +
Sbjct: 1005 PGP--KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQK 1062
Query: 824 PEPARPPLSALAPPHGSPDPPVPELLTGR--GSGKRGRRGGGGLRGINGEARPARGRKPG 881
+ P +S++ P G P P L G G +G G GL G+ G PG
Sbjct: 1063 GDKGDPGISSIGLP-GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT--------PG 1113
Query: 882 SRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG----PHSE 937
++ +PG GT G + P GG P P PPG P +
Sbjct: 1114 AKGQPGLPGFP-GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172
Query: 938 DLKVPPGVVRKSRRGRRRKYNP 959
+ P G +K G+ NP
Sbjct: 1173 GIPGPAG--QKGEPGQPGFGNP 1192
Score = 107 bits (267), Expect = 6e-23
Identities = 217/816 (26%), Positives = 266/816 (32%), Gaps = 132/816 (16%)
Query: 140 PGPPSARPPCRVP--PTTP-LNGGPG-SLPPEPPSV--------------SQAFPTLAGP 181
PGP R P +P P TP L G PG P P + S FP L GP
Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145
Query: 182 GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS-LNAPSYNWGAALRSSLVPS 240
G PP + GS LP G +P P PP I L P+ +P
Sbjct: 146 PG--PPGIPGMKGEPGSIIMSSLP-GPKGNPGYPGPPGIQGLPGPTG----------IPG 192
Query: 241 DLGSPPAPHASSSPPSDPPLFHCSDALT-----PPPLPPSNNLPAHPGPASQPPVSSATM 295
+G PP P PP P L + P L PGP Q +
Sbjct: 193 PIG-PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH 355
+ G G P GP PP + P PP +G + P
Sbjct: 252 DVEFQKGDQG-LPGDRGPPGPPGIRG------------PPGPPGGEKGEKGEQGEPGKRG 298
Query: 356 SSSLRPSQRRPRRPPTVFRLLEGRG-PQTPRRSRPRAPA-----PVPQPFSLPEPSQPIL 409
+P + P + L G P P R + P P +P P I
Sbjct: 299 ----KPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354
Query: 410 PSVLSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGS 468
+GLP PG G + G PP G P P P + G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP 414
Query: 469 LSSVPGAPAPPAASKAPVVPSPVLQS-----PSEGLGMGAGPACPLPP----LAGGEAFP 519
S+PG P AP +P P + PS+ + P P P L G +
Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474
Query: 520 FPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPP 579
+ G G G G LP G P P L G G P+ L
Sbjct: 475 GDKGDTCFNCIGTGISGPPGQPGLP---GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531
Query: 580 PGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP-----PSNLLASFLPLLALGPT 634
PG PG P PG P ++ L P AP P LP L GP
Sbjct: 532 PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP-GPK 590
Query: 635 AGDGEGSAEGAGGPSGEP-FSGL-GDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692
G + +G GP G P GL G++ P + PP PP + + +G P
Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGP-MGPPGFGPPGPVGEKG------IQGVAGNP 643
Query: 693 PQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGD--LSS 750
QP + PGP T T PG L P N GR + L GD L
Sbjct: 644 GQPGI-----PGPKGDPGQT-ITQPGKPGL---PGNPGRDGDV-------GLPGDPGLPG 687
Query: 751 LTSSPGALPSLLQP--PGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQP 808
PG S +P PG L G G + PG PP + L+ PP P
Sbjct: 688 QPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPP 742
Query: 809 EAPCLPPESPASALEPEPARPPL----SALAP--PHGSPDPPVPELLTGRG--------- 853
P P P AL P P L AL P G P PP P TG
Sbjct: 743 GFPG-PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV 801
Query: 854 --SGKRGRRGGGGLRGINGEARPARGRKPGSRREPG 887
+G+ G G GL GI + P PG +PG
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837
Score = 101 bits (251), Expect = 4e-21
Identities = 285/1083 (26%), Positives = 334/1083 (30%), Gaps = 282/1083 (26%)
Query: 140 PGPPSAR---PPCRVPPTTPLNGG-------PGSLPPEPPSVS--QAFPTLAGPGGLFPP 187
PGPP A PP PP P G PG P PP + P L GP G P
Sbjct: 385 PGPPGAAVMGPPG--PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP 442
Query: 188 RL------ADPVPSGGSSSPRFL--------------------------PRGNAPSPAPP 215
+ +P P G SP P G P P
Sbjct: 443 HIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLP 502
Query: 216 PPPAISLNAPSYNWGAALRSSLVPSDL-GSPPAPHASSSPPSDPPLFHCSDALTPPPL-- 272
PP SL P + P L G P AP A P S D LT P +
Sbjct: 503 GPPG-SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG---EPGDILTFPGMKG 558
Query: 273 -------------------PPSNNLPAHPGPASQP-----------PVSSATMHLPLVLG 302
P + LP PGP +P P + LP +G
Sbjct: 559 DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618
Query: 303 PLG----------------------GAPTVEGPGAPPFLASSLLSAAAKAQHPP------ 334
P+G G P + GP P + +P
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678
Query: 335 LPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP-PTVFRLLEGR--GPQTPRR----- 386
LP L G+ P + + P P P P F + G P TP R
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGI-PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEG 737
Query: 387 --SRPRAPAPVPQP-FSLP-EPSQPILPSVLSLLGLPT----PGPSHSDGSFNLLGSDAH 438
P P P +P F+LP P P LP LG PGP G L G
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL--- 794
Query: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
P P G QP P LPG PG P P +P G
Sbjct: 795 --PGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852
Query: 499 LGMGAGPA---CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQP-PPSP 554
L + P P P A G P SP +GFPG G + + +G P PP P
Sbjct: 853 LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---MGPPGPPGP 909
Query: 555 LLNHSLFGV--------LTGGGGQPPP--------EPLLPPPGGP------------GPP 586
L GV L G G P P EP LP P GP G P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969
Query: 587 LAPGEPEGPSLLVASLLPPPPSDL-------LPPPSAPPSNLLASFLPLLALGP-----T 634
PG P LP P LP P P N P L +GP T
Sbjct: 970 GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL-IGPPGLKGT 1028
Query: 635 AGD----GEGSAEGAGGPSGEP----FSGL----GD-----LSPLLFPPLSAPPTLIAL- 676
GD G EG GPSG P GL GD +S + P L P L
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088
Query: 677 ----NSALLAATLDPP-SGTPPQPCVLSAP-------QPGPPTSSVTTATT-------DP 717
N + + DP G P P P PGPP + +P
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148
Query: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ--PPG-PLLSGQLG 774
G G P G P + P G + + PG P PPG P LSGQ G
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKP--GQDGIPGPAGQKGEPGQ-PGFGNPGPPGLPGLSGQKG 1205
Query: 775 LQLLPG----GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPP 830
LPG G P P E P +Q PP PP SP ALE P
Sbjct: 1206 DGGLPGIPGNPGLPGPKGE---PGFHGFPGVQGPPG-------PPGSPGPALEGPKGNPG 1255
Query: 831 LSALAPPHGSPDPPVPELLTGRG-----SGKRGRRGGGGLRGINGEARPARGRKPGSRRE 885
G P P P L G G G G+ G GL G+ G+ P PG +
Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP-----PGLQGN 1310
Query: 886 PGRLALKWGTRG--------GFNGQMERSPRRTHHWQHNGELAEGGAEPKDPP----PPG 933
PGR L G +G GF G S G A P+ P PPG
Sbjct: 1311 PGRPGLN-GMKGDPGLPGVPGFPGMKGPSG------------VPGSAGPEGEPGLIGPPG 1357
Query: 934 PHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRP 993
PPG+ S + K + + + P P +P P PG P
Sbjct: 1358 --------PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP-GPTGPPGDP 1408
Query: 994 AKN 996
+N
Sbjct: 1409 GRN 1411
Score = 99.8 bits (247), Expect = 1e-20
Identities = 227/869 (26%), Positives = 270/869 (31%), Gaps = 177/869 (20%)
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL--FPPRLADPVPSG 196
SPG P + P P + G PGS+ + P GP G+ P P P G
Sbjct: 136 SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAAL---RSSLVPSDLGSPPAPHASSS 253
P + PP PP L P N G + L PP P S
Sbjct: 196 PPGPPGLM--------GPPGPP--GLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQIS 245
Query: 254 PPSDP--PLFHCSDALTP----PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG-- 305
P F D P PP PP P PGP P G G
Sbjct: 246 EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKD 303
Query: 306 ---GAPTVEGPGAPPFLASSLLSAAAKAQH----PPLPP------PST------------ 340
G P + G P K Q PP PP P T
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363
Query: 341 --LQGRRPRAQAPSASHSSSL-RPSQRRPRRPPTVFRLLEGRGPQ----TPRRSRPRAPA 393
L G + P L P PP RG + P S P P
Sbjct: 364 PGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPG 423
Query: 394 PVPQPFS-----LPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLG--------SDAHLP 440
QP + P P+ P +P + PGP S G L G D
Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483
Query: 441 PPPTLSSGSPPQPRHPIQPSLPG----------------TTSGSLSSVPGAPAPPAASKA 484
T SG P QP P P PG T L +PGAP P +
Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGS 543
Query: 485 PVVPSPVLQSP-----SEGLGMGAGPACP-LPPLAGGEAFP-FPSPE---QGLALSG--- 531
P +L P LG P P LP G + P P P+ G+ G
Sbjct: 544 KGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Query: 532 -------AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQP------------- 571
G PG +G + P G PP P+ + GV G GQP
Sbjct: 604 PPGNPGLPGLPGNIGPMGPP---GFGPPGPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659
Query: 572 --PPEPLLPPPGG-------PGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLL 622
P +P LP G PG P PG+P P + + P P LP P P
Sbjct: 660 TQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG--- 716
Query: 623 ASFLPLLALGPTAGDGEGSAEGAGGPSGEP-FSGLGDLSPLLFPPLSAPPTLIALNSALL 681
P + GP G G GP G P F G P PP L AL
Sbjct: 717 ---FPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL- 771
Query: 682 AATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG--RPPQLLSPL 739
P G PGPP PG + L P G P P+
Sbjct: 772 -----GPKG--------DRGFPGPP--------GPPGRTGLDGLPGPKGDVGPNGQPGPM 810
Query: 740 LGASLLGDLSSLTSSPGALPSLLQPPG-PLLSGQLGLQLLPGGGAPPPLSEASSPLACLL 798
L G P +P + PG + G+ G PG P P E SP +
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP---GI 867
Query: 799 QSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRG 858
P P +P LP ++ AS P G P PP P + GR SG G
Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGF------PGTKGEMGMMGPPGPPGPLGIPGR-SGVPG 920
Query: 859 RRGGGGLRGINGEARPARGRKPGSRREPG 887
+G GL+G G P G K GS+ EPG
Sbjct: 921 LKGDDGLQGQPGLPGPT-GEK-GSKGEPG 947
Score = 76.6 bits (187), Expect = 1e-13
Identities = 158/590 (26%), Positives = 192/590 (32%), Gaps = 100/590 (16%)
Query: 417 GLPT-PGPSHSDGSFNLLGSDAHLPPP-PTLSSGSPPQPRHPIQPSLPGTT----SGSLS 470
GLP PGP G G D PP P G P P P P LPG +
Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQ 119
Query: 471 SVPGAPAPPAASKAPVVPS-PVLQSPSEGLGM-------GAGPACPLPPLAGGEAFPFPS 522
+PG P P P LQ P G+ G+ LP G +P P
Sbjct: 120 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP 179
Query: 523 PEQGLALSGAGFPGMLGALPLPLSLGQPP-----PSPLLNHSLFGVLTGGGGQPPPEPLL 577
QGL G PG +G P P L PP P P N L G G+ + L
Sbjct: 180 GIQGLP-GPTGIPGPIGP-PGPPGLMGPPGPPGLPGPKGNMGL--NFQGPKGEKGEQGLQ 235
Query: 578 PPPGGPGP------PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP--PSNLLASFLPLL 629
PPG PG P+ +G L PP P + PP P
Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295
Query: 630 ALGPTAGDGEGSAEGAGGPSGEP-FSG----------LGDLSPLLFPPLSAP----PTLI 674
G DGE G G G+P + G GD P P L P I
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDPGASSLGKAPSNSGRPP 733
+ L G P + P PGPP ++V PG + G P
Sbjct: 356 GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP- 414
Query: 734 QLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGG--APPPLSEAS 791
G S+ G L PGA P L PPGP G + P P P
Sbjct: 415 -------GISIPGP-PGLDGQPGA-PGLPGPPGP-----AGPHIPPSDEICEPGPPGPPG 460
Query: 792 SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTG 851
SP LQ Q C + + P +P L L P GS P +
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCF--NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK---- 514
Query: 852 RGSGKRGRRGGGGLRGING-EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRT 910
G++G+ G G +G+ G P PGS+ EPG + G +G
Sbjct: 515 ---GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKG------------- 558
Query: 911 HHWQHNGELAEGGAEPKDPPPPGPHSED--------LKVPPGVVRKSRRG 952
GEL GA P P PG +D P G+ K RG
Sbjct: 559 ----DKGELGSPGA-PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603
Score = 75.5 bits (184), Expect = 2e-13
Identities = 138/538 (25%), Positives = 175/538 (32%), Gaps = 77/538 (14%)
Query: 125 SPGEGASPQMFHTVSPGPPSARPPCRV------PPTTPLNGGPGSLPPEPPSVSQAFPTL 178
S GE P + PG P P P L+G PG P P + P
Sbjct: 962 SKGEKGEPGL-----PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP-- 1014
Query: 179 AGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLV 238
PG + PP L + G P+ + PS P P + L + G SS+
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074
Query: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298
L P P +P + ++ P LP LP PG QP + P
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGI---KGSVGDPGLP---GLPGTPGAKGQPGLPG----FP 1124
Query: 299 LVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGR--RPRAQAPSASHS 356
GP G + GP P L HP P P +G+ + P+
Sbjct: 1125 GTPGP-PGPKGISGPPGNPGLPGEP-GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKG 1182
Query: 357 SSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLL 416
+P P P L G Q P P P EP P V
Sbjct: 1183 EPGQPGFGNPGPPG-----LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPP 1237
Query: 417 GLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGA 475
G P +PGP+ N P P G P P P LPG +G + G
Sbjct: 1238 GPPGSPGPALEGPKGN---------PGPQGPPGRPGLPGPEGPPGLPG--NGGIKGEKGN 1286
Query: 476 PAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP-LPPLAGGEAFPFPSPEQGLALSGAGF 534
P P P + Q P G+ P P L + G P G+ +G
Sbjct: 1287 PGQPGLPGLPGLKGD--QGPP---GLQGNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSGV 1340
Query: 535 PGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEG 594
PG G P +G P P L S ++ G PP PG PG PG P+G
Sbjct: 1341 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPP-----GIPGQPGLKGLPG-PQG 1394
Query: 595 PSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEP 652
P L P P+ PP P N L F DG G +G G G+P
Sbjct: 1395 PQGL------PGPTG---PPGDPGRNGLPGF-----------DGAGGRKGDPGLPGQP 1432
Score = 62.8 bits (151), Expect = 2e-09
Identities = 104/379 (27%), Positives = 130/379 (34%), Gaps = 61/379 (16%)
Query: 140 PGPPSARPPCRVP--PTTP-------LNGGPGS--LPPEP-PSVSQAFPTLAGPGGLF-- 185
PG P A+ +P P TP ++G PG+ LP EP P P GP G
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168
Query: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
P + P P+G P GN P PP P +S D G P
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGN---PGPPGLPGLSGQK---------------GDGGLP 1210
Query: 246 PAPHASSSP-PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPL 304
P P P P FH + PP PP + PA GP P GP
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP-------------GPQ 1257
Query: 305 G--GAPTVEGPGAPPFLASS--LLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360
G G P + GP PP L + + P LP L+G Q P + R
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG----DQGPPGLQGNPGR 1313
Query: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPIL--PSVLSLLGL 418
P + P + + G + P P + P +P + P P L PS S++
Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGP-SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1372
Query: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG-TTSGSLSSVPGAPA 477
GP G L G P P G P P + LPG +G PG P
Sbjct: 1373 GDAGPPGIPGQPGLKGLPG--PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430
Query: 478 PPAASKAPVVPSP-VLQSP 495
P P P LQ P
Sbjct: 1431 QPGTRGLDGPPGPDGLQGP 1449
Score = 57.8 bits (138), Expect = 5e-08
Identities = 117/454 (25%), Positives = 146/454 (32%), Gaps = 101/454 (22%)
Query: 533 GFPGMLGALPLPLSLG-QPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGE 591
GFPG+ G LP G + PP P G+ G P P+ + PPG PG P PG
Sbjct: 51 GFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI----PGPPGPKGIRGPPGLPGFPGTPGL 106
Query: 592 PEGP-------------------------SLLVASLLPPPPSDLLPPPSAPPSNLLASFL 626
P P S L PP +P P +++ S L
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSL 166
Query: 627 PLLALGPTAG---DGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683
P GP G +G GP+G P G + P P L PP
Sbjct: 167 P----GPKGNPGYPGPPGIQGLPGPTGIP----GPIGPPGPPGLMGPP------------ 206
Query: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGAS 743
P G P + GP + G L P G+ + P+
Sbjct: 207 ---GPPGLPGPKGNMGLNFQGP--------KGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255
Query: 744 LLGD--LSSLTSSPGALPSLLQPPGPL--LSGQLGLQLLPGGGAPPPLSEASSPLACLLQ 799
GD L PG P + PPGP G+ G Q PG P +
Sbjct: 256 QKGDQGLPGDRGPPGP-PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG------- 307
Query: 800 SLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP---VPELLTGRGSGK 856
QP P LP + EP R G P PP +P TG G+
Sbjct: 308 -------QPGIPGLPGD---PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 357
Query: 857 RGRRGGGGLRGINGE-ARPARGRKPGSRREPGRLALKWGTRGGFNGQM----ERSPRRTH 911
+G G GL G GE P PG PG + GF G+ + P
Sbjct: 358 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417
Query: 912 HWQHNGELAEGGAE--PKDPPPPGPHSEDLKVPP 943
G + GA P P P GPH +PP
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPH-----IPP 446
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 118 bits (296), Expect = 2e-26
Identities = 207/732 (28%), Positives = 279/732 (38%), Gaps = 154/732 (21%)
Query: 153 PTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSP 212
P PL G +P PP PG P A P P P+ LP S
Sbjct: 1015 PRAPL----GPVPVRPP-----------PG---PELSAQPTPG---PVPQVLPASLMVSA 1053
Query: 213 APPPPPAISLNAPSYNWGAALRSSLVPSDLGSP---PAPHASSSPPSDPPLFHCSDALTP 269
+P PP I + P G L L P+ P P+P S S PP + L+
Sbjct: 1054 SPAGPPLIPASRPP---GPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPP----TPTLSL 1106
Query: 270 PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAK 329
P PP+ P PA PP S+++ PL + P P P A +++ +A
Sbjct: 1107 KPTPPA---PVRLSPA--PPPGSSSLLKPLTVPPGYTFP----PAAATTTSTTTATATTT 1157
Query: 330 AQHPPLPPPSTL------QGRRPRAQAPSASHSSSL--RPSQRRPRRPPTVFRLLEGRGP 381
A P P P L Q R P + S +SL RP P F++ +
Sbjct: 1158 AVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLT 1217
Query: 382 QTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPP 441
T + R A V QP +P+ +V+ L+ + G +L+ AH+
Sbjct: 1218 LTGAQVRQLA---VGQP-------RPLQRNVVHLVS--------AGGQHHLISQPAHVAL 1259
Query: 442 PPTLSSGSPPQPRHPIQPSLPGTTSG----SLSSVPGAPAPPAASKAPVVPSPVLQSPSE 497
++ P P + S P TT SL P + VV V Q+P +
Sbjct: 1260 IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD 1319
Query: 498 GLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML--------GALPLPLSLGQ 549
GL P+PPLA P P P +G P +L G LP P +LG
Sbjct: 1320 GL-------TPVPPLA-----PAPRPPS------SGLPAVLNPRPTLTPGRLPTP-TLGT 1360
Query: 550 ---PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPP 606
P P+P L L ++ P PE PG PL P L V S LP P
Sbjct: 1361 ARAPMPTPTLVRPLLKLVHS----PSPEVSASAPGAA--PLTISSP----LHVPSSLPGP 1410
Query: 607 PSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPP 666
S +P P++ P LAS + P + + P P + S L P
Sbjct: 1411 ASSPMPIPNSSP---LASPVSSTVSVPLS---------SSLPISVPTTLPAPASAPLTIP 1458
Query: 667 LSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP 726
+SAP T+ A ALL + TPP V+ A PGPP+ + + A+ A +LG A
Sbjct: 1459 ISAPLTVSASGPALLTSV------TPPLAPVVPAA-PGPPSLAPSGASPSASALTLGLAT 1511
Query: 727 ----SNSGRP--PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG 780
S+S P P LL+P +S + L+S T +P P L+ P L S P
Sbjct: 1512 APSLSSSQTPGHPLLLAPT--SSHVPGLNS-TVAPACSPVLV-PASALAS--------PF 1559
Query: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHG- 839
AP P +S LA + Q P AP P++ A P P PL LAP G
Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALAT-PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGA 1618
Query: 840 -----SPDPPVP 846
S PVP
Sbjct: 1619 APVLASSQTPVP 1630
Score = 116 bits (290), Expect = 1e-25
Identities = 192/657 (29%), Positives = 248/657 (37%), Gaps = 120/657 (18%)
Query: 125 SPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQA---FPTLAGP 181
+P +G +P +P PPS+ P + P L PG LP ++A PTL P
Sbjct: 1316 APRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLT--PGRLPTPTLGTARAPMPTPTLVRP 1373
Query: 182 GGLF----PPRLADPVPSGGS---SSPRFLPR---GNAPSPAPPPPPAISLNAPSYNWGA 231
P ++ P SSP +P G A SP P P + + S
Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV 1433
Query: 232 ALRSSLVPSDLGSPPAPHAS--SSPPSDPPLFHCSD-----ALTPPPLPPSNNLPAHPGP 284
L SSL S + PAP ++ + P S P S ++TPP P +PA PGP
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPV---VPAAPGP 1490
Query: 285 ASQPPVSSATMHLPLVLGPLGGAPTVEG---PGAPPFLASS------LLSAAAKAQHPPL 335
S P ++ L LG L AP++ PG P LA + L S A A P L
Sbjct: 1491 PSLAPSGASPSASALTLG-LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVL 1549
Query: 336 PPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPV 395
P S L P A P+ + +S L P+ + T P AP
Sbjct: 1550 VPASALASPFPSAPNPAPAQASLLAPASSASQALAT-----------------PLAPMAA 1592
Query: 396 PQPFSL-PEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPR 454
PQ L P P+ P+ P L +L P+PG + P L+S P P
Sbjct: 1593 PQTAILAPSPAPPLAP--LPVLA-PSPGAA------------------PVLASSQTPVPV 1631
Query: 455 HPIQPSLPGTTSGSLSSVPGAPAPPAA--SKAPVVPSPV---LQSPSEGLGMGAGPACPL 509
S PGT+ S S VP AP P A S ++P+PV L SP+ + PA L
Sbjct: 1632 MA-PSSTPGTSLASASPVP-APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPA--L 1687
Query: 510 PPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGG 569
P GG SP Q L+L G G P G P +L P S L+ + G
Sbjct: 1688 APTLGGS-----SPSQTLSL-GTGNPQ--GPFPTQ-TLSLTPASSLVPTPAQTLSLAPG- 1737
Query: 570 QPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPS--DLLPPPSAPPSNLLASFLP 627
PP P P PPLAP P GP+ L P S LL P S L S P
Sbjct: 1738 -PPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASV--QTLTLSPAP 1794
Query: 628 LLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDP 687
+ LGP A A+ S S L+ A P + + S L P
Sbjct: 1795 VPTLGPAA------AQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRL------P 1842
Query: 688 PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASL 744
S P L + P PP++ A+S G PP SP SL
Sbjct: 1843 VSKDEPDTLTLRSGPPSPPST----------ATSFGGPRPRRQPPPPPRSPFYLDSL 1889
Score = 112 bits (279), Expect = 2e-24
Identities = 240/913 (26%), Positives = 316/913 (34%), Gaps = 159/913 (17%)
Query: 139 SPGPPSARPPCRVPPTTPLNGGP--GSLPPEPPSVSQAFPTLAGPGGLFP------PRLA 190
+P P P R PP L+ P G +P P+ + AGP L P P L
Sbjct: 1014 NPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPP-LIPASRPPGPVLL 1072
Query: 191 DPVPSGGSSSPRFLPR------GNAPSPAP-------PPPPAISLNAPSYNWGAALRSSL 237
P+ S P+ LP G + P P PP P AP + L+
Sbjct: 1073 PPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLT 1132
Query: 238 VPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP----LPPSNNLPAHPGPA-------- 285
VP PPA ++S + A TP P L P G
Sbjct: 1133 VPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLAS 1192
Query: 286 -SQPPVSSATMHLPLVLGPLGGAPTVEGP-------GAP-PFLASSLLSAAAKAQHPPLP 336
+Q PV++A PL G T+ G G P P + + +A QH +
Sbjct: 1193 LAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLIS 1252
Query: 337 PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPR----------- 385
P+ + + A P + S L S PT L P
Sbjct: 1253 QPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIV 1312
Query: 386 -RSRPR-APAPVPQPFSLPEPSQPILPSVLSLLGLPTPG--PSHSDGSFNLLGSDAHLPP 441
R PR PVP P P LP+VL+ TPG P+ + G+ + A +P
Sbjct: 1313 VRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGT-----ARAPMPT 1367
Query: 442 P----PTLSSGSPPQPRHPIQPSLPGTTSGSLSS---VPGAPAPPAASKAPVVPSPVLQS 494
P P L P P + S PG ++SS VP + PA+S P+ S L S
Sbjct: 1368 PTLVRPLLKLVHSPSPE--VSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLAS 1425
Query: 495 P---------SEGLGMGAGPACPLP---PLAGGEAFPFPSPEQGLALSGAGFPGM---LG 539
P S L + P P PL + P G AL + P + +
Sbjct: 1426 PVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVP 1485
Query: 540 ALPLPLSLGQPPPSPLLNHSLFGVLTG---GGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596
A P P SL SP + G+ T Q P PLL P PG +
Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH---VPGLNSTVA 1542
Query: 597 LLVASLLPPPPSDLLPPPSAP-PSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSG 655
+ +L P + P PSAP P+ AS L P + + A P P +
Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLL-----APASSASQALATPLA-PMAAPQTA 1596
Query: 656 LGDLSPLLFPPLSAPPTLIALNSA--LLAATLDP-----PSGTPPQPCVLSAPQPGPPT- 707
+ L+P PPL+ P L A +LA++ P PS TP ++P P P
Sbjct: 1597 I--LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654
Query: 708 ---SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP 764
SS T P S L PS + L+P L +L G S T S G P
Sbjct: 1655 LAPSSTQTMLPAPVPSPL---PSPASTQTLALAPALAPTLGGSSPSQTLSLGTG----NP 1707
Query: 765 PGPLLSGQLGLQLLPGGGAPPP----LSEASSPLACLLQSLQIPPEQPEAPCLPP-ESPA 819
GP + L L P P LS A P Q+L + P P AP P +PA
Sbjct: 1708 QGPFPTQTLSLT--PASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPA 1765
Query: 820 SALEPEPARPPLSALAPPHGSP----DPPVPEL---------LTGRGSGKRGRRGGGGLR 866
L PA S LAP PVP L L + + +
Sbjct: 1766 HTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVV 1825
Query: 867 GINGEAR---PARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG 923
+G A R P S+ EP L L+ G SP T + GG
Sbjct: 1826 SASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPP---------SPPST-------ATSFGG 1869
Query: 924 AEPKDPPPPGPHS 936
P+ PPP P S
Sbjct: 1870 PRPRRQPPPPPRS 1882
Score = 73.6 bits (179), Expect = 9e-13
Identities = 205/848 (24%), Positives = 275/848 (32%), Gaps = 154/848 (18%)
Query: 144 SARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPR 202
S P R P P P P P S A P L P ++ PVP +
Sbjct: 2422 STTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALV------PVPVSAPVPISAPNPIT 2475
Query: 203 FLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFH 262
LP PSP PP S P + + P +PP PS P L
Sbjct: 2476 ILPVHILPSPPPP-----SQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLL-- 2528
Query: 263 CSDALTPPPLPPS---NNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPF- 318
L PP +P S NLP P ++ + L L + + T PP
Sbjct: 2529 ----LGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKD 2584
Query: 319 ---LASSLLSAAAK-AQHPPLPPPSTLQ-GRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
+A +L + K P P TL+ G P Q A S+ P
Sbjct: 2585 LLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPL 2644
Query: 374 RLLEGRGPQTPRRSRPRAPAPVP--------------QPFSLPEPSQPIL------PSVL 413
+ E G + P + P P P S PE Q ++ PS
Sbjct: 2645 CVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTS 2704
Query: 414 SLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG---------- 463
S GPS + +D + T G PP P+ + LPG
Sbjct: 2705 SSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPK--VLRKLPGRLVTVVEEKE 2762
Query: 464 ------TTSGSLSS-VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGE 516
G+ S+ VPG A+ +P V S S +G G A P L
Sbjct: 2763 LVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIG-GPCEAAPSSSLPTPP 2821
Query: 517 AFPFPSPEQ-GLALSGAGFP----GMLGALPLPL---SLGQPPP---SP---------LL 556
PF + L ++G G P G L A+ P G+PP SP
Sbjct: 2822 QQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAP 2881
Query: 557 NHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG-EPEGPSLLVASLLPPPPSDLLPP-- 613
+ +L G G P PE L+ P L PG +P GP + P+ LL P
Sbjct: 2882 SSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPV------HRPNPLLSPVE 2935
Query: 614 ---PSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAP 670
PP A LP+ +AGDG + P P L+PL PPL
Sbjct: 2936 KRRRGRPPK---ARDLPIPGTISSAGDGNSESRTQPPPHPSP------LTPL--PPLLVC 2984
Query: 671 PTLIALNS-ALLAATLDPPS---GTPPQPCVLSAPQPGPPTSSVTTATTD---------- 716
PT N+ + + PP G PP+ P P +T+ +
Sbjct: 2985 PTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQP 3044
Query: 717 --PGASSLGKAPSNSGRPPQLLSPL----------------LGASLLGDLSSLTSSPGAL 758
G S + + RP L+ L + A + DL S PG L
Sbjct: 3045 QGQGESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGL 3104
Query: 759 PSLLQPPGPLLSGQL-GLQLLPGGGAPP------PLSEASSPLACLLQSLQIPPEQPEAP 811
L PP L+ +L +L PG PP P A +P+ + QP +P
Sbjct: 3105 E--LTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSP 3162
Query: 812 CLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGE 871
L PE E E + P P P L+ G + + G
Sbjct: 3163 -LGPEGSVEESEAEASGEEEEGDGTPRRRPGP--RRLVGTTNQGDQRILRSSAPPSLAGP 3219
Query: 872 ARPARGRK 879
A RGRK
Sbjct: 3220 AVSHRGRK 3227
Score = 66.2 bits (160), Expect = 1e-10
Identities = 181/743 (24%), Positives = 258/743 (34%), Gaps = 188/743 (25%)
Query: 329 KAQHPPLPPPSTLQGRR-PRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRS 387
KA+ P P + R RA+ A+H+ + Q R P PR S
Sbjct: 2384 KAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTP-------------PRCS 2430
Query: 388 --RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL 445
R R P P P+P P + +P+++ + + P P + +L H+ P
Sbjct: 2431 PARERVPRPAPRPRPTPASAPAAIPALVPV-PVSAPVPISAPNPITIL--PVHILP---- 2483
Query: 446 SSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPS-PVLQSPSEGLGMGAG 504
SPP P S P T + P A PP A V PS P+L P
Sbjct: 2484 ---SPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGP--------- 2531
Query: 505 PACPLPPLAGGEAFPFP-SPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGV 563
P+ P+ A P PE L A P L L S + SL
Sbjct: 2532 PSVPIS--ASVTNLPLGLRPEAELCAQAL-------ASPESLELASVASSETSSLSLV-- 2580
Query: 564 LTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLA 623
PP+ LLP + +LP +L PSAP L A
Sbjct: 2581 --------PPKDLLP-------------------VAVEILPVSEKNLSLTPSAPSLTLEA 2613
Query: 624 SFLPLLALGPTAGDGEGSAEGAGG---PSGEPFS-GLGDLSPLLFPPLSAPPT-----LI 674
+P + SAEG P GE + + + L PP +A L
Sbjct: 2614 GSIP----NGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLE 2669
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAP-------- 726
A ++ P+ +P +P L + P++S ++AT+ P S + P
Sbjct: 2670 ADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTS-SSATSSPEGPSPARPPRRRTSADV 2728
Query: 727 ----SNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGG 782
+GRP Q P + L G L ++ + Q G + L+PG
Sbjct: 2729 EIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAST------LVPG-- 2780
Query: 783 APPPLSEAS-SPLACLLQSLQIPPEQPE--APCLPPESPASALEPEPARPPLSALAPPHG 839
+SE S SP + ++S+ P P PC +P+S+L P +P ++ G
Sbjct: 2781 ----VSETSASPGSPSVRSMSGPESSPPIGGPC--EAAPSSSLPTPPQQPFIARRHIELG 2834
Query: 840 SPDPPVPELLTGRGSGKRGRRGGGGLRGINGEA-RPARGRKPGSRREPGRLALKWGTRGG 898
+TG GS + G G L I A + RGR P R P RG
Sbjct: 2835 ---------VTGGGSPENG---DGALLAITPPAVKRRRGRPPKKNRSPADAG-----RG- 2876
Query: 899 FNGQMERSPRRTHHWQHNGE----------LAEGGAEPK---DPPPPGP---HSEDLKVP 942
++ +P T + NG +A+ EP+ P P GP H + +
Sbjct: 2877 ----VDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLS 2932
Query: 943 PGVVRKSRRGRRRKYN--PTRNSNSSRQDITLE----PSPTARAAVPLPP---------- 986
P V K RRGR K P + SS D E P P PLPP
Sbjct: 2933 P--VEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVA 2990
Query: 987 -------------RARPGRPAKN 996
+ + GRP KN
Sbjct: 2991 NTVTTVTISTSPPKRKRGRPPKN 3013
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 116 bits (291), Expect = 9e-26
Identities = 225/927 (24%), Positives = 323/927 (34%), Gaps = 190/927 (20%)
Query: 142 PPSARPPCRVPPTTPLNGGPGSLPPE----PPSVSQAFPTL------------AGPGGLF 185
P PP P G GS P P S S + T +G G
Sbjct: 509 PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
Query: 186 PPRLADPVPSGGSSSP----RFLP---------RGNAPSPAPPPPPAISLNAPSYNWGAA 232
P P +GG ++P RFLP R + PP P++ + AP G
Sbjct: 569 GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSV-IAAPPSGGGNI 627
Query: 233 LRSSLVPSD----------LGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHP 282
L++ ++P + + S PAP + P+ P + +T P S+ P
Sbjct: 628 LQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSST----P 683
Query: 283 GP-ASQP-PVSSATMHLPLVLGPLGGAPTVEG-----PGAPPFLASSLLSAAAKAQHPPL 335
P AS+P P S P GA T G PG P L SL+ + K+
Sbjct: 684 VPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPGGSP-LGVSLVYSDKKSAAATS 739
Query: 336 PPPSTLQGRRPRAQAPSASHSSSL---RPSQRRPRRPPTVFRLLEGR-------GPQTPR 385
P P + G + + ++L P P PP V + +G G
Sbjct: 740 PAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA-PPAVQFIAQGAPGGGTTAGSGAGA 798
Query: 386 RSRPRAPAP--VPQPFSLPEPSQ--------PILPSVLSLLGLPTPGPSHSDGSFNLLGS 435
S P P P + QP +L + P LP L + P P P G+
Sbjct: 799 GSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAP----------GT 848
Query: 436 DAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGS---LSSVPGAPAPPAASKAPVVPSPVL 492
A P S P P I+ +LP TS + L++ P P P P P
Sbjct: 849 KAAAP--------SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA 900
Query: 493 QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP--LPLSLGQP 550
QS S G + L P G P +P + GAG P L + P +P+ G
Sbjct: 901 QSVSPVQAPPPGGSAQLLP--GKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
Query: 551 PPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDL 610
PPS ++ + V T G PP L P PGP P + PS + +
Sbjct: 959 PPSKIIQLTPVPVSTPSGLVPP----LSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHA 1014
Query: 611 LPPPSAPPSNLLASFLPLLALGPTAGDGEG-SAEGAGGPSG-EPFSGLGDLSPLLFP--- 665
LP ++P S+ + + + GPT+ G ++ G GP+ +P G +PLL P
Sbjct: 1015 LPLGTSPASSQAGT---VTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQ-APLLAPGQV 1070
Query: 666 ---PLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS--SVTTATTDPG 718
P+ +P P A + S P L+ P PP+ +V T+TT P
Sbjct: 1071 GVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPA 1130
Query: 719 ASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQL- 777
A+ L K P + T++P P P S G
Sbjct: 1131 ATILPKGPP---------------------APATATPA-------PTSPFPSATAGSMTY 1162
Query: 778 -LPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAP 836
L A P +A + + S+ + + A P +P LEP P R P + +
Sbjct: 1163 SLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESE 1222
Query: 837 PHGSPDPPVPELL------TGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLA 890
G P PP P L T R S P + S + P +A
Sbjct: 1223 LEGQPTPPAPPPLPETWTPTARSS----------------PPLPPPAEERTSAKGPETMA 1266
Query: 891 LKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSR 950
K+ P + W+ G+ E EP PP P P V PG +S
Sbjct: 1267 SKF-------------PSSSSDWRVPGQGLENRGEPPTPPSPAPAP---AVAPGGSSESS 1310
Query: 951 RGRRRKYNPTR-NSNSSRQDITLEPSP 976
GR P R + + + + + P P
Sbjct: 1311 SGRAAGDTPERKEAAGTGKKVKVRPPP 1337
Score = 78.2 bits (191), Expect = 4e-14
Identities = 128/479 (26%), Positives = 165/479 (34%), Gaps = 100/479 (20%)
Query: 435 SDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS 494
S H PP PP P S S SS + A A S + + S ++
Sbjct: 502 SFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFS--LGSGTFKA 559
Query: 495 PSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGALPLPLSLGQP 550
G G AGP P PP AGG A P + L + A F P +G G
Sbjct: 560 QESGQGSTAGPLRPPPPGAGGPATP-SKATRFLPMDPATFRRKRPESVG--------GLE 610
Query: 551 PPSPLLNHSLFGVLTGGGGQPPPEPLLPP------------PGGPGPPLAPGEPEGP--- 595
PP P S+ GGG +LPP P P P LA G P P
Sbjct: 611 PPGP----SVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSR 666
Query: 596 --SLLVASLLPPPPSDLLPPPSAP-PSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEP 652
+ +V +++ P S +P S P P++ A P G G GS G P G
Sbjct: 667 PAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVS 726
Query: 653 F-----SGLGDLSPLLFPPLSAPPTLIALNSA------LLAATLDPPSGTPPQPCVLSAP 701
SP P L A P L + A LL T P G P P V
Sbjct: 727 LVYSDKKSAAATSPA--PHLVAGPLLGTVGKAPATVTNLLVGT--PGYGAPAPPAVQFIA 782
Query: 702 QPGP---------------PTSSVTTATTDPGASSLGKAPSNS-------GRPPQLLSPL 739
Q P P V PGA LGKA + P QL
Sbjct: 783 QGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGA--LGKAGGITQVQYILPTLPQQLQVAP 840
Query: 740 LGASLLGDLSSLTSSPGALPSL--LQPPGPLLSGQLGLQLLPGGG---------APPPLS 788
A G ++ S P S+ PPG +G++ P G APPP +
Sbjct: 841 APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA 900
Query: 789 EASSPLACLLQSLQIPPEQPEAPCLPPE------SPASALEPEPARPPLSALAPPHGSP 841
++ SP +Q PP A LP + +P+ ++ A PL ++PP P
Sbjct: 901 QSVSP-------VQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVP 952
Score = 64.7 bits (156), Expect = 4e-10
Identities = 127/507 (25%), Positives = 169/507 (33%), Gaps = 112/507 (22%)
Query: 126 PGEGASPQMFHTVSPGP--------PSARPPCRV---PPTTPLNGGPGSLPPEPPSVSQA 174
PG + ++ +P P PSA PP P P GG L P V A
Sbjct: 868 PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLA 927
Query: 175 FPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALR 234
P+++ GG P+P S P +P N A PP I L +
Sbjct: 928 APSMSVRGG----GAGQPLPL--VSPPFSVPVQNG---AQPPSKIIQLTPVPVS------ 972
Query: 235 SSLVPSDLGSPPAPHASSSPPSDPP--LFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS 292
PS L P +P P S P L S +T + LP PAS +
Sbjct: 973 ---TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ-AGT 1028
Query: 293 ATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHP------PLPPPSTLQG-RR 345
T + P LG T GP P F+ L + A P P+P P
Sbjct: 1029 VTSYGPTSSVALGF--TSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAA 1086
Query: 346 PRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPS 405
P +A +S S P+ P P+ Q P P + P
Sbjct: 1087 PGGPVITAFYSGSPAPTSSAPLAQPS----------QAPPSLVYTVATSTTPPAATILPK 1136
Query: 406 QPILPSVLSLLGLPT-PGPSHSDGS--FNLLGSDAHLPPPPTL----------------- 445
P P+ + PT P PS + GS ++L+ A P P
Sbjct: 1137 GPPAPATAT--PAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194
Query: 446 -SSGSP-PQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGA 503
+SG P P PR P++P + S + G P PPA P +P +S
Sbjct: 1195 GASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARS--------- 1245
Query: 504 GPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGV 563
+ PLPP P+ E+ S G M P S + P L N
Sbjct: 1246 --SPPLPP---------PAEER---TSAKGPETMASKFPSSSSDWRVPGQGLENR----- 1286
Query: 564 LTGGGGQPPPEPLLPPPGGPGPPLAPG 590
G+PP PP P P +APG
Sbjct: 1287 -----GEPP----TPPSPAPAPAVAPG 1304
Score = 50.1 bits (118), Expect = 1e-05
Identities = 168/736 (22%), Positives = 243/736 (33%), Gaps = 156/736 (21%)
Query: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP---------LPPSNNLPAHPGPAS 286
S+ PS+ PA H +S S P + A PP PP P PGP
Sbjct: 52 SVQPSE-AQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGP 110
Query: 287 QPPVSSATMHLPLVLGPLGGAPTVE----GPGAPPFLAS--------SLLSAAAKAQHPP 334
P L +V G PT E GP P L S + LS + P
Sbjct: 111 PHP-------LGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLP 163
Query: 335 LPPPSTLQGRRPRA------QAPSASHSSSLRPSQRRP---RRPPTVFRLLEGRGPQTPR 385
LPP RR ++ + S+S P++R RRP F +
Sbjct: 164 LPPGK----RRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFS-------- 211
Query: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL 445
R RA P IL LG P + D +F + +AH P
Sbjct: 212 -KRHRALVHQRHPNQDNRTVSKILGEWWYALG-PKEKQKYHDLAFQV--KEAHFKAHPDW 267
Query: 446 SSGSPPQPRH-----PIQPSLPG----TTSGSLSSVPGAPAPPAASKA-PVVPSPVLQSP 495
+ + + P L G T S+S A AP +S+ V +L S
Sbjct: 268 KWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSD 327
Query: 496 SEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL 555
++ G + A L + G P + A S +G + G G+ L
Sbjct: 328 TKAPGSSSCGAERLHTVGG------PGSARPRAFSHSGVHSLDG--------GEVDSQAL 373
Query: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPS 615
L +++G P+P G PGP APG EG +L P P+
Sbjct: 374 --QELTQMVSGPASYSGPKPSTQY-GAPGPFAAPG--EGGALAATGRPPLLPTRASRSQR 428
Query: 616 APPSNLLASFLPLLAL------GPTAGDGEGSAE------------GAGGPSGEPFSGLG 657
A ++ + ++ A DG G+ + +G SGE G
Sbjct: 429 AASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNK 488
Query: 658 DLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDP 717
+F P +I + LDP PP P V G S+ +++ + P
Sbjct: 489 GFGRKVFSP------VIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYG---SAPSSSASSP 539
Query: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSG----QL 773
+SS A S S LG+ G + S G+ L+PP P G
Sbjct: 540 ASSSASAATSFS----------LGS---GTFKAQESGQGSTAGPLRPPPPGAGGPATPSK 586
Query: 774 GLQLLP--------------GGGAPPPLSEASSPLA---CLLQSLQIPPEQPE------- 809
+ LP GG PP S ++P + +LQ+L +PP + E
Sbjct: 587 ATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGAR 646
Query: 810 -----APCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGG 864
AP L +PA+ L A + + P +P P + G + G
Sbjct: 647 VPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAG 706
Query: 865 LRGINGEARPARGRKP 880
R G G P
Sbjct: 707 ARTEMGTGSRVPGGSP 722
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 14/86 (16%)
Query: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLP-----PEPPSVSQAFPTLAGPGGLFPPRLAD 191
T + PP A P VPP T P P P+P S S T L PP
Sbjct: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPP---- 1578
Query: 192 PVPSGGSSSPRFLPRGNAPSPAPPPP 217
P G P + AP P+PPPP
Sbjct: 1579 --PESGPGQPGW---EGAPQPSPPPP 1599
Score = 37.4 bits (85), Expect = 0.071
Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 17/136 (12%)
Query: 318 FLASSLLSAAAKAQHPPLPPPST---LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFR 374
F S+ +AA +A++ + P L+ R R + A+ + P P
Sbjct: 1483 FFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPL------- 1535
Query: 375 LLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHS-DGSFNLL 433
P P APAP P P P+P+ P S + P P P S G
Sbjct: 1536 ------PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
Query: 434 GSDAHLPPPPTLSSGS 449
G+ PPPP S+ +
Sbjct: 1590 GAPQPSPPPPGPSTAA 1605
Score = 37.0 bits (84), Expect = 0.093
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 10/73 (13%)
Query: 434 GSDAHLP-PPPTLSSGSP---PQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS------K 483
G++A LP PPPT ++ +P P P P+ P + SG+ + P P PP + +
Sbjct: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
Query: 484 APVVPSPVLQSPS 496
PSP PS
Sbjct: 1590 GAPQPSPPPPGPS 1602
Score = 33.9 bits (76), Expect = 0.79
Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 16/134 (11%)
Query: 317 PFLASSLLSAA---AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
PFLA S + ++AQ P P ++ Q + P A A P RPP
Sbjct: 42 PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA- 100
Query: 374 RLLEGRGPQTPRR----SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGS 429
E GP P + P P + + P +P L S H D
Sbjct: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE--------SDHDDAF 152
Query: 430 FNLLGSDAHLPPPP 443
+++ + LP PP
Sbjct: 153 LSIMSPEIQLPLPP 166
Score = 33.9 bits (76), Expect = 0.79
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 284 PASQPPVSSATMHLPLVLGPLGG-APTVEGPGAPPFLASSLLSAAAKAQHPPLPPP 338
P QPP + A + +P G APT G P + S S A+A PPLPPP
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAA-PPLPPP 1578
Score = 33.5 bits (75), Expect = 1.0
Identities = 34/111 (30%), Positives = 38/111 (34%), Gaps = 33/111 (29%)
Query: 606 PPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSG-EPFSGLGDLSPLLF 664
PP P P PP+ A+ P + AGGP P S G
Sbjct: 1528 PPGAEAPLPVPPPTGTAAAPAP-------------TPSPAGGPDPTSPSSDSGTAQAA-- 1572
Query: 665 PPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATT 715
PPL PP PP P QP APQP PP +TA T
Sbjct: 1573 PPL--PP---------------PPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
Score = 33.5 bits (75), Expect = 1.0
Identities = 32/99 (32%), Positives = 35/99 (35%), Gaps = 26/99 (26%)
Query: 205 PRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCS 264
P AP P PPP + AP+ PS G P +SP SD
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPT------------PSPAGGPDP----TSPSSDS-----G 1567
Query: 265 DALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP 303
A PPLPP P GP QP A P GP
Sbjct: 1568 TAQAAPPLPP----PPESGP-GQPGWEGAPQPSPPPPGP 1601
Score = 33.1 bits (74), Expect = 1.3
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 7/80 (8%)
Query: 575 PLLPPPGGPGP-PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL-LASFLPLLALG 632
P PPG P P+ P P+ A+ P P P P++P S+ A P L
Sbjct: 1524 PTEQPPGAEAPLPVPP-----PTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPP 1578
Query: 633 PTAGDGEGSAEGAGGPSGEP 652
P +G G+ EGA PS P
Sbjct: 1579 PESGPGQPGWEGAPQPSPPP 1598
Score = 32.3 bits (72), Expect = 2.3
Identities = 32/102 (31%), Positives = 36/102 (35%), Gaps = 24/102 (23%)
Query: 174 AFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPA--ISLNAPSYNWGA 231
A PT PG P PVP P G A +PAP P PA +PS + G
Sbjct: 1522 ATPTEQPPGAEAPL----PVPP---------PTGTAAAPAPTPSPAGGPDPTSPSSDSGT 1568
Query: 232 ALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLP 273
A +PP P S P P PPP P
Sbjct: 1569 A---------QAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
Score = 32.3 bits (72), Expect = 2.3
Identities = 29/95 (30%), Positives = 32/95 (33%), Gaps = 22/95 (23%)
Query: 502 GAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLF 561
GA P+PP G A P P+P S AG P + PP P
Sbjct: 1530 GAEAPLPVPPPTGTAAAPAPTP------SPAGGPDPTSPSSDSGTAQAAPPLP------- 1576
Query: 562 GVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596
PPPE PG G P P GPS
Sbjct: 1577 ---------PPPESGPGQPGWEGAPQPSPPPPGPS 1602
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 107 bits (267), Expect = 6e-23
Identities = 215/807 (26%), Positives = 262/807 (32%), Gaps = 157/807 (19%)
Query: 141 GPPSARPPCRVPPTTPLNGGPGSL-PPEPPSVSQAFPTLAGPGGLFPPRLA---DPVPSG 196
GP R P P + G PG PP PP P G GG F P+L+ D +G
Sbjct: 118 GPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGP----PGPPGLGGNFAPQLSYGYDEKSTG 173
Query: 197 GSSSPRFLPRG-NAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255
G S P P G + P P PP A P P PP
Sbjct: 174 GISVPG--PMGPSGPRGLPGPPGA--------------------------PGPQGFQGPP 205
Query: 256 SDPPLFHCSDALTP--PPLPPSNN-------LPAHPGPASQPPVSSA-----TMHLPLVL 301
+P S + P PP PP N P PG P A T LP +
Sbjct: 206 GEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMK 265
Query: 302 GPLG-----GAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH- 355
G G GA GP P S A Q P P + RP A P+ +
Sbjct: 266 GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG--ERGRPGAPGPAGARG 323
Query: 356 -----SSSLRPSQRRPRRPPTVFRLLEGR---GPQTPRRSR-PRAPAPVPQPFSLPEPSQ 406
++ P P PP + + GPQ PR S P+ P P P P+
Sbjct: 324 NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP---PGPAG 380
Query: 407 PILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTS 466
P+ PG G+ G+ P + P P+ P P P S
Sbjct: 381 AAGPA-------GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433
Query: 467 GSLSSVPGAPAPPAASKAPVVPSPV-LQSP-----SEGLGMGAGPACP--LPPLAGGEAF 518
G PGAP + A P PV +Q P EG G P LP G
Sbjct: 434 GE----PGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG 489
Query: 519 P----FPSPEQGLALSG----AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQ 570
P FP + G G PG G P G+P + L LTG G
Sbjct: 490 PGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK---GLTGSPGS 546
Query: 571 PPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLL---PPPPSDLLPPPSAPPSNLLASFLP 627
P P+ PPG G PG P P + + P P P A + P
Sbjct: 547 PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPG---P 603
Query: 628 LLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDP 687
A+GP DGE A+G GP+G P G+ P P P P
Sbjct: 604 PGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGPAGSPGFQGLP-----------GPAGP 651
Query: 688 P--SGTPPQ---PCVLSAPQPG--------PPTSSVTTATTDPGASSLGKAPSNSGRPPQ 734
P +G P + P L AP P P V G AP N G
Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK-- 709
Query: 735 LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG----GGAPPPLSEA 790
GD +PGA S P + G+ G LPG G P
Sbjct: 710 -----------GD----AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754
Query: 791 SSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAP-PHGSPDPPVPELL 849
SP ++ L P P P P + PA P + AP G P PP P
Sbjct: 755 GSPGKDGVRGL-TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813
Query: 850 TG--RGSGKRGRRGGGGLRGINGEARP 874
G G+ G +G G G G+A P
Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGP 840
Score = 95.1 bits (235), Expect = 3e-19
Identities = 227/907 (25%), Positives = 293/907 (32%), Gaps = 146/907 (16%)
Query: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSS 199
PGP A P P G G+ + + FP GP G P P P G S
Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG-GPPGPKGNSG 434
Query: 200 SPRFLPRGNAPSPAPPPPPAISLNAPSYNWG----AALRSSLVPSDLGSPP----APHAS 251
P P + A P + + P G R P+ L PP P +
Sbjct: 435 EPG-APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSR 493
Query: 252 SSPPSD---PPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG--G 306
P +D P + +P P P + PG A +P + LP G G G
Sbjct: 494 GFPGADGVAGPKGPAGERGSPGPAGPKGS----PGEAGRPGEAG----LPGAKGLTGSPG 545
Query: 307 APTVEGPGAPPFLAS--------SLLSAAAKAQHPPLPPPSTLQGRRPRA-----QAPSA 353
+P +G PP A A +A P P G +A P
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605
Query: 354 SHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSR--PRAPAPVPQPFSLPEPSQPILPS 411
+ + + + + PP RG Q P S P P P +P + +P
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665
Query: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLPPP----PTLSSGSPPQPRHPIQPSLPGTTSG 467
L PGPS + G G PP P ++G+P PG
Sbjct: 666 -----DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS 720
Query: 468 SLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGL 527
PG P A +P P +G AGP G + P +GL
Sbjct: 721 --QGAPGLQGMPGERGAAGLPGP------KGDRGDAGP-------KGADGSPGKDGVRGL 765
Query: 528 ALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQP-PPEP--LLPPPGGPG 584
G PG GA P G+ PS + G G+P PP P PPG G
Sbjct: 766 T-GPIGPPGPAGA---PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821
Query: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEG 644
P A GEP G + PP P+ P+ PP GP G A+G
Sbjct: 822 QPGAKGEP-GDAGAKGDAGPPGPAG----PAGPP-------------GPIGNVGAPGAKG 863
Query: 645 AGGPSGEP-FSGLGDLSPLLFPP-------LSAPPTLIALNSALLAATLDPPSGTPPQPC 696
A G +G P +G + + PP PP P+G P +
Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE-- 921
Query: 697 VLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPG 756
PGPP + + PGA AP G PQ ++ G L PG
Sbjct: 922 ---VGPPGPPGPAGEKGS--PGADGPAGAPGTPG--PQGIAGQRGVVGLPGQRGERGFPG 974
Query: 757 ALPSLLQPPGPL-LSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCL-- 813
LP PG SG G + PG PP L+ + P +P
Sbjct: 975 -LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE-----SGREGAPGAEGSPGRDG 1028
Query: 814 PPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEAR 873
P + E PA PP + AP G+P P P +GK G RG G G G
Sbjct: 1029 SPGAKGDRGETGPAGPPGAPGAP--GAPGPVGP-------AGKSGDRGETGPAGPAGPVG 1079
Query: 874 PARGRKP----GSRREPGRLALKWGTRG-----GFNGQMERSPRRTHHWQHNGELAEGGA 924
P R P G R + G + G RG GF+G + A G A
Sbjct: 1080 PVGARGPAGPQGPRGDKGETG-EQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPA 1138
Query: 925 EPKDPP--PPGPHSEDLKVPPGVV-RKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAA 981
P+ PP P + L PG + RGR P P P
Sbjct: 1139 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG-----------PPGPPGPPG 1187
Query: 982 VPLPPRA 988
P PP A
Sbjct: 1188 PPGPPSA 1194
Score = 81.3 bits (199), Expect = 4e-15
Identities = 160/570 (28%), Positives = 188/570 (32%), Gaps = 109/570 (19%)
Query: 380 GPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLG-LPTPGPSHSDGSFNLLGSDAH 438
GP PR AP PQ F P P +P P +G PGP +G D
Sbjct: 182 GPSGPRGLPGPPGAPGPQGFQGP-PGEPGEPGASGPMGPRGPPGPPGKNGD------DGE 234
Query: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
P PP P+ LPGT + +PG S G
Sbjct: 235 AGKPGRPGERGPPGPQGA--RGLPGT-----AGLPGMKGHRGFS---------------G 272
Query: 499 LGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQP-PPSPLLN 557
L G A P AG + P E G PG +G LP G+P P P
Sbjct: 273 LDGAKGDAGP----AGPKGEPGSPGENGA-------PGQMGPRGLPGERGRPGAPGPAGA 321
Query: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEP--------EGPSLLVASLLPPPPSD 609
G TG G P P PPG PG A GE EGP + PP P+
Sbjct: 322 RGNDGA-TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380
Query: 610 LLPPPSAP-----PSNLLASFLPLLA--------LGPTAGDGEGSAEGAGGPSGEPFS-- 654
P P P A+ P +A GP+ G G G G SGEP +
Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440
Query: 655 GLGDLSPLLFPP---LSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSV 710
GD P + PP A P+G P P P G P +
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500
Query: 711 TTATTDPGASSLGKAPSN-SGRPPQLLSPLLGASLLGDLSSLTSSPGAL--PSLLQPPGP 767
P P+ G P + P G + L LT SPG+ PPGP
Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRP--GEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558
Query: 768 LLSGQLGLQLLPGG----------GAPPPLSEASSPLACLLQSLQIPP-------EQPEA 810
+GQ G PG G P P A P + + PP + EA
Sbjct: 559 --AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEA 616
Query: 811 PCLPPESPASAL----EPEPARPP----LSALAPPHGSPDPP----VPELLTGRG-SGKR 857
P PA E PA P L A P G P VP L G SG R
Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676
Query: 858 GRRGGGGLRGINGEARPARGRKPGSRREPG 887
G RG G RG+ G PA R G+ PG
Sbjct: 677 GERGFPGERGVQGPPGPAGPR--GANGAPG 704
Score = 76.6 bits (187), Expect = 1e-13
Identities = 143/545 (26%), Positives = 175/545 (32%), Gaps = 90/545 (16%)
Query: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS----QAFPTLAGPGGLFPPR--LADPV 193
PGP R P G G+ P P S Q P G GL P+ D
Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGA-PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749
Query: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSS 253
P G SP P PP PA AP + P+ P
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPA---GAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806
Query: 254 PPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQ-----PPVSSATMHLPLVLGPLG--G 306
PP + PP PG A PP + P +G +G G
Sbjct: 807 PPGP------AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPG 860
Query: 307 APTVEGPGAPPFLASSLLSAAAKAQHP----------PLPPPSTLQGRRPRAQAPSASHS 356
A G PP A+ AA + P P P G+ PR + A
Sbjct: 861 AKGARGSAGPPG-ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG-- 917
Query: 357 SSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLL 416
RP + P PP GP + S P A P P + P + ++
Sbjct: 918 ---RPGEVGPPGPP---------GPAGEKGS-PGADGPAGAPGT---PGPQGIAGQRGVV 961
Query: 417 GLP----------TPGPSHSDGSFNLLGSDAHLPPP----------PTLSSGSPPQPRHP 456
GLP PGPS G G+ PP P SG P
Sbjct: 962 GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAE 1021
Query: 457 IQPSLPGTTSGSLSSVPGAPA-PPAASKAPVVPSPV---LQSPSEGLGMGAGPACPLPPL 512
P G+ PA PP A AP P PV +S G AGPA P+ P+
Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081
Query: 513 -AGGEAFP-------FPSPEQG-LALSG-AGFPGMLGALPLPLSLGQPPPSPLLNHSLFG 562
A G A P + EQG + G GF G+ G P S G+ PS +
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141
Query: 563 VLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLL 622
G G P + L PG GPP P G + + PP P PP P +
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPP----GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFD 1197
Query: 623 ASFLP 627
SFLP
Sbjct: 1198 FSFLP 1202
Score = 54.3 bits (129), Expect = 6e-07
Identities = 116/488 (23%), Positives = 147/488 (30%), Gaps = 106/488 (21%)
Query: 125 SPGEGASPQMFHTVSPGPPSARP-------PCRVPPTTPLNGGPGSL-PPEPPSVSQAFP 176
SPG+ + + P P+ P P T G PG P PP
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP------- 808
Query: 177 TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAP-----PPPPAISLNAPSYNWGA 231
GP G P AD P +G+A P P PP P ++ AP
Sbjct: 809 ---GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK--G 863
Query: 232 ALRSSLVPSDLG--------SPPAPHASSSPPSDP----------PLFHCSDALTPPPLP 273
A S+ P G PP P ++ PP P P A P +
Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923
Query: 274 PSNNLPAHPGPASQP--PVSSATMHLPLVLGPLG-----------------GAPTVEGPG 314
P P PGPA + P + P GP G G P + GP
Sbjct: 924 P----PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979
Query: 315 APPFLASSLLSAAAKAQHPPLPPPSTL--QGRRPRAQAPSASHSSSLRPS--------QR 364
P ++ + P+ PP G R AP A S S +
Sbjct: 980 GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039
Query: 365 RPRRPPTVFRLLEGRGPQTPR-------RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLG 417
P PP GP P + P PA P P+ P P
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR------ 1093
Query: 418 LPTPGPSHSDGSFNLLG----SDAHLPPPPTLSSGS--PPQPRHPIQPSLPGTTSGS--- 468
G + G + G S PP P S G P P P P ++G+
Sbjct: 1094 -GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152
Query: 469 --LSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQG 526
L+ +PG PP PV P G P P PP AG + P P Q
Sbjct: 1153 DGLNGLPGPIGPPGPRGRTGDAGPV--GPP---GPPGPPGPPGPPSAGFDFSFLPQPPQE 1207
Query: 527 LALSGAGF 534
A G +
Sbjct: 1208 KAHDGGRY 1215
Score = 52.0 bits (123), Expect = 3e-06
Identities = 112/427 (26%), Positives = 135/427 (31%), Gaps = 95/427 (22%)
Query: 566 GGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASF 625
G G P PPG G P PG LP PP PP P L +F
Sbjct: 115 GDTGPRGPRGPAGPPGRDGIPGQPG------------LPGPPG---PPGPPGPPGLGGNF 159
Query: 626 LPLLALG-PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAAT 684
P L+ G G S G GPSG L PP + P
Sbjct: 160 APQLSYGYDEKSTGGISVPGPMGPSGP--------RGLPGPPGAPGP-----------QG 200
Query: 685 LDPPSGTPPQPCVLSAPQ-----PGPPTSSVTTATTDPGASSLGKAPSNSGRP-PQLLSP 738
P G P +P S P PGPP + D G + P G P PQ
Sbjct: 201 FQGPPGEPGEPGA-SGPMGPRGPPGPPGKN-----GDDGEAGKPGRPGERGPPGPQGARG 254
Query: 739 LLGASLLGDLSSLTSSPG--ALPSLLQPPGPL----------LSGQLGLQLLPG----GG 782
L G + L + G P GP GQ+G + LPG G
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG 314
Query: 783 APPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARP--PLSALAPP--H 838
AP P + A + P P P PP P + A P P + P
Sbjct: 315 APGPAGARGNDGA----TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370
Query: 839 GSPDPPVPELLTG-----RGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKW 893
G P PP P G G+ G +G G GI G R P + PG
Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--- 427
Query: 894 GTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGR 953
G +G N +P GE G + PPGP E+ +RG
Sbjct: 428 GPKG--NSGEPGAPGSKGDTGAKGEPGPVGVQ----GPPGPAGEE----------GKRGA 471
Query: 954 RRKYNPT 960
R + PT
Sbjct: 472 RGEPGPT 478
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 107 bits (267), Expect = 6e-23
Identities = 146/511 (28%), Positives = 197/511 (38%), Gaps = 81/511 (15%)
Query: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
+VS S PP + PPTTP+ GG P P + P L P L P A P G
Sbjct: 261 SVSSSGASGAPPTK-PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG 319
Query: 197 GSSSPRFLPRGNAPSP---------APPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
+ P LP G+ PSP PP P APS + SL P+ +P
Sbjct: 320 LGAQP--LP-GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH-------SLPPASSSAPAP 369
Query: 248 P-----HASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLG 302
P +SSS + S + + P P S LP++P P S + P
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429
Query: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362
P + V G PP L A + A HP PPST G + A P ++H +
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNA-HPGPFPPST--GAQSTAHPPVSTHHHHHQQQ 486
Query: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPF----SLPEPSQPILPSVLSLLGL 418
Q++ ++ + + + Q S P P P P S + PS+ SL
Sbjct: 487 QQQQQQQ----QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Query: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
P PGP AHLPPP + S S P P P ++S + SS +
Sbjct: 543 P-PGP-------------AHLPPPHSQVSYSQAGPNGP-----PVSSSSNSSSSTSQGSY 583
Query: 479 PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML 538
P + SPS+G P P+P + A + +A S AG+
Sbjct: 584 PCSH----------PSPSQGPQGAPYPFPPVPTVTTSSA-TLSTVIATVASSPAGY--KT 630
Query: 539 GALPLPLSLGQPPPSPLLNHSLFGVLTGGG---GQPPPEPLLPPPG--GPGPPLAPG--E 591
+ P P G+ PSP + T G G PP PPG G PP PG +
Sbjct: 631 ASPPGPPPYGKRAPSP----GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFK 686
Query: 592 PEGPSLLVASLLPPPPSDL--LPPPSAPPSN 620
P P++ L P PS L LPPP A P++
Sbjct: 687 PGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
Score = 89.4 bits (220), Expect = 2e-17
Identities = 210/824 (25%), Positives = 268/824 (32%), Gaps = 177/824 (21%)
Query: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298
PSDL S + SDP + T P + ++ +S A + P
Sbjct: 102 PSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP 161
Query: 299 LVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSS 358
L P P P P S H P+ PP++ + P P A
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP----PGA----- 212
Query: 359 LRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL-PEPSQPILPSVLSLLG 417
P P +L G P P+ + P P P+ PI S G
Sbjct: 213 --PPPHPQLYPGGTGGVLSG-PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG 269
Query: 418 L-PTPGPSHSDGSFNLLGS---------DAHLPPPPTL-----SSGSP------PQPRHP 456
PT P+ G NL + +LPPPP L +S SP P P H
Sbjct: 270 APPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL 329
Query: 457 IQPSLPGTTSGSLSSVPG-----APA----PPAASKAPVVP--------SPVLQSPSEGL 499
P G G L P AP+ PPA+S AP P S + S
Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389
Query: 500 GMGAGPACPLPPLAGGEAFP--FPSPEQGLALSGAGFPGMLGALPLP----LSLGQPPPS 553
+ A P P ++P FP P +LS + P LP S G PPP
Sbjct: 390 SSSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
Query: 554 P---LLNHS-----LFGVLTG-------------------------------------GG 568
P LL +S F TG G
Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506
Query: 569 GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPL 628
PPP P P G P S + SL P PP P PP + S+
Sbjct: 507 SGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPG----PAHLPPPHSQVSYSQA 561
Query: 629 LALGP---TAGDGEGSAEGAGGPSGEPFSGLGDL-SPLLFPPLSAPPTLIALNSALLAAT 684
GP ++ + S P P G +P FPP+ T A S ++A
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 685 LDPPSG----TPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPS-NSGRPP--QLLS 737
P+G +PP P P P + TAT P G PS +G PP + S
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSP--GAYKTAT--PPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 738 PLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL 797
P G S T PG LP P GP GL LP PPP + AS P
Sbjct: 678 PPAGPGTFKP-GSPTVGPGPLP----PAGP-----SGLPSLP----PPPAAPASGPPLSA 723
Query: 798 LQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKR 857
Q Q P E+ E PESP PP SP PP P+++ +
Sbjct: 724 TQIKQEPAEEYET----PESP----------------VPPARSPSPP-PKVVDVPSHASQ 762
Query: 858 GRRGGGGL-RGINGEAR------PARGRKPGS---------RREPGRLALKWGTR-GGFN 900
R L RG N AR P G K RRE + A + R
Sbjct: 763 SARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERE 822
Query: 901 GQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPG 944
+ ER + + + +LA+ G P + P GP PG
Sbjct: 823 REKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPG 866
Score = 72.0 bits (175), Expect = 3e-12
Identities = 165/643 (25%), Positives = 212/643 (32%), Gaps = 91/643 (14%)
Query: 387 SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS 446
+RP P P+ P P S P P S P+ P+ G A + PP +
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEA-SFEPHPSVTPT---------GYHAPMEPPTSRM 205
Query: 447 SGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP--------SEG 498
+PP P PG T G LS P P A+ + P+ Q P S
Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265
Query: 499 LGMGAGPA-CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS--PL 555
GA P P P+ GG P P A FP + LP PPP+ PL
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPP--------ANFPHVTPNLP-------PPPALRPL 310
Query: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGP---PLAPGEPEGPSLLVASLLPPPPSDLLP 612
N S G G QP P LP P G L PG +GP+L + PP S P
Sbjct: 311 NNAS--ASPPGLGAQPLPGH-LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP 367
Query: 613 PPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSA--- 669
APP S + +A S+ + S P S P FPP ++
Sbjct: 368 ---APPMRFPYS----SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
Query: 670 ---PPTLIALNSALLAATLDPPSGTPPQPCVL--SAPQPGP-PTSSVTTATTDPGASSLG 723
PP + A P PP +L S PGP P S+ +T P S+
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
Query: 724 KAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGP------LLSGQLG-LQ 776
+ Q +S PGA P L+ +S LG L+
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 777 LLPGGGA--PPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL 834
P G A PPP S+ S Q P P S +++ P P S
Sbjct: 541 PYPPGPAHLPPPHSQVSYS--------QAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPS 591
Query: 835 APPHGS--PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALK 892
P G+ P PPVP + T + A P G P +R P A K
Sbjct: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP-GPPPYGKRAPSPGAYK 650
Query: 893 WGTRGGFNGQMERSPRRTHHWQHNGELAEGGA---EPKDP-------PPPGPHSEDLKVP 942
T G+ S R + G G +P P PP GP P
Sbjct: 651 TATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPP 710
Query: 943 PGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLP 985
P S G + + + P P AR+ P P
Sbjct: 711 PPAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 44.3 bits (103), Expect = 6e-04
Identities = 61/232 (26%), Positives = 77/232 (33%), Gaps = 50/232 (21%)
Query: 784 PPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL--APPHGSP 841
PPPL S Q P QPEA P S P PP S + APP G+P
Sbjct: 161 PPPLFPPSP------QPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP-GAP 213
Query: 842 DPPVPELLTGRGSG-----KRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTR 896
PP P+L G G G +GGG + G G + P + +
Sbjct: 214 -PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP-------NGGKQHPPPTTPISVSSS 265
Query: 897 GGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG-PHSEDLKVPPGVVRKSRRGRRR 955
G + P GG P PPP PH PP +R
Sbjct: 266 GASGAPPTKPPTTP---------VGGGNLPSAPPPANFPHVTPNLPPPPALR-------- 308
Query: 956 KYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGR----PAKNKRRKLAP 1003
P N+++S + +P P +P P G P K LAP
Sbjct: 309 ---PLNNASASPPGLGAQPLP---GHLPSPHAMGQGMGGLPPGPEKGPTLAP 354
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 107 bits (267), Expect = 6e-23
Identities = 146/511 (28%), Positives = 197/511 (38%), Gaps = 81/511 (15%)
Query: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
+VS S PP + PPTTP+ GG P P + P L P L P A P G
Sbjct: 261 SVSSSGASGAPPTK-PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG 319
Query: 197 GSSSPRFLPRGNAPSP---------APPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
+ P LP G+ PSP PP P APS + SL P+ +P
Sbjct: 320 LGAQP--LP-GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH-------SLPPASSSAPAP 369
Query: 248 P-----HASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLG 302
P +SSS + S + + P P S LP++P P S + P
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429
Query: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362
P + V G PP L A + A HP PPST G + A P ++H +
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNA-HPGPFPPST--GAQSTAHPPVSTHHHHHQQQ 486
Query: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPF----SLPEPSQPILPSVLSLLGL 418
Q++ ++ + + + Q S P P P P S + PS+ SL
Sbjct: 487 QQQQQQQ----QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Query: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
P PGP AHLPPP + S S P P P ++S + SS +
Sbjct: 543 P-PGP-------------AHLPPPHSQVSYSQAGPNGP-----PVSSSSNSSSSTSQGSY 583
Query: 479 PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML 538
P + SPS+G P P+P + A + +A S AG+
Sbjct: 584 PCSH----------PSPSQGPQGAPYPFPPVPTVTTSSA-TLSTVIATVASSPAGY--KT 630
Query: 539 GALPLPLSLGQPPPSPLLNHSLFGVLTGGG---GQPPPEPLLPPPG--GPGPPLAPG--E 591
+ P P G+ PSP + T G G PP PPG G PP PG +
Sbjct: 631 ASPPGPPPYGKRAPSP----GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFK 686
Query: 592 PEGPSLLVASLLPPPPSDL--LPPPSAPPSN 620
P P++ L P PS L LPPP A P++
Sbjct: 687 PGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
Score = 89.4 bits (220), Expect = 2e-17
Identities = 210/824 (25%), Positives = 268/824 (32%), Gaps = 177/824 (21%)
Query: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298
PSDL S + SDP + T P + ++ +S A + P
Sbjct: 102 PSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP 161
Query: 299 LVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSS 358
L P P P P S H P+ PP++ + P P A
Sbjct: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP----PGA----- 212
Query: 359 LRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL-PEPSQPILPSVLSLLG 417
P P +L G P P+ + P P P+ PI S G
Sbjct: 213 --PPPHPQLYPGGTGGVLSG-PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG 269
Query: 418 L-PTPGPSHSDGSFNLLGS---------DAHLPPPPTL-----SSGSP------PQPRHP 456
PT P+ G NL + +LPPPP L +S SP P P H
Sbjct: 270 APPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL 329
Query: 457 IQPSLPGTTSGSLSSVPG-----APA----PPAASKAPVVP--------SPVLQSPSEGL 499
P G G L P AP+ PPA+S AP P S + S
Sbjct: 330 PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389
Query: 500 GMGAGPACPLPPLAGGEAFP--FPSPEQGLALSGAGFPGMLGALPLP----LSLGQPPPS 553
+ A P P ++P FP P +LS + P LP S G PPP
Sbjct: 390 SSSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
Query: 554 P---LLNHS-----LFGVLTG-------------------------------------GG 568
P LL +S F TG G
Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506
Query: 569 GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPL 628
PPP P P G P S + SL P PP P PP + S+
Sbjct: 507 SGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPG----PAHLPPPHSQVSYSQA 561
Query: 629 LALGP---TAGDGEGSAEGAGGPSGEPFSGLGDL-SPLLFPPLSAPPTLIALNSALLAAT 684
GP ++ + S P P G +P FPP+ T A S ++A
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 685 LDPPSG----TPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPS-NSGRPP--QLLS 737
P+G +PP P P P + TAT P G PS +G PP + S
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSP--GAYKTAT--PPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 738 PLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL 797
P G S T PG LP P GP GL LP PPP + AS P
Sbjct: 678 PPAGPGTFKP-GSPTVGPGPLP----PAGP-----SGLPSLP----PPPAAPASGPPLSA 723
Query: 798 LQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKR 857
Q Q P E+ E PESP PP SP PP P+++ +
Sbjct: 724 TQIKQEPAEEYET----PESP----------------VPPARSPSPP-PKVVDVPSHASQ 762
Query: 858 GRRGGGGL-RGINGEAR------PARGRKPGS---------RREPGRLALKWGTR-GGFN 900
R L RG N AR P G K RRE + A + R
Sbjct: 763 SARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERE 822
Query: 901 GQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPG 944
+ ER + + + +LA+ G P + P GP PG
Sbjct: 823 REKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPG 866
Score = 72.0 bits (175), Expect = 3e-12
Identities = 165/643 (25%), Positives = 212/643 (32%), Gaps = 91/643 (14%)
Query: 387 SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS 446
+RP P P+ P P S P P S P+ P+ G A + PP +
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEA-SFEPHPSVTPT---------GYHAPMEPPTSRM 205
Query: 447 SGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP--------SEG 498
+PP P PG T G LS P P A+ + P+ Q P S
Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265
Query: 499 LGMGAGPA-CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS--PL 555
GA P P P+ GG P P A FP + LP PPP+ PL
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPP--------ANFPHVTPNLP-------PPPALRPL 310
Query: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGP---PLAPGEPEGPSLLVASLLPPPPSDLLP 612
N S G G QP P LP P G L PG +GP+L + PP S P
Sbjct: 311 NNAS--ASPPGLGAQPLPGH-LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP 367
Query: 613 PPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSA--- 669
APP S + +A S+ + S P S P FPP ++
Sbjct: 368 ---APPMRFPYS----SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
Query: 670 ---PPTLIALNSALLAATLDPPSGTPPQPCVL--SAPQPGP-PTSSVTTATTDPGASSLG 723
PP + A P PP +L S PGP P S+ +T P S+
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
Query: 724 KAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGP------LLSGQLG-LQ 776
+ Q +S PGA P L+ +S LG L+
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 777 LLPGGGA--PPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL 834
P G A PPP S+ S Q P P S +++ P P S
Sbjct: 541 PYPPGPAHLPPPHSQVSYS--------QAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPS 591
Query: 835 APPHGS--PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALK 892
P G+ P PPVP + T + A P G P +R P A K
Sbjct: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP-GPPPYGKRAPSPGAYK 650
Query: 893 WGTRGGFNGQMERSPRRTHHWQHNGELAEGGA---EPKDP-------PPPGPHSEDLKVP 942
T G+ S R + G G +P P PP GP P
Sbjct: 651 TATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPP 710
Query: 943 PGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLP 985
P S G + + + P P AR+ P P
Sbjct: 711 PPAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 44.3 bits (103), Expect = 6e-04
Identities = 61/232 (26%), Positives = 77/232 (33%), Gaps = 50/232 (21%)
Query: 784 PPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL--APPHGSP 841
PPPL S Q P QPEA P S P PP S + APP G+P
Sbjct: 161 PPPLFPPSP------QPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP-GAP 213
Query: 842 DPPVPELLTGRGSG-----KRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTR 896
PP P+L G G G +GGG + G G + P + +
Sbjct: 214 -PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP-------NGGKQHPPPTTPISVSSS 265
Query: 897 GGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG-PHSEDLKVPPGVVRKSRRGRRR 955
G + P GG P PPP PH PP +R
Sbjct: 266 GASGAPPTKPPTTP---------VGGGNLPSAPPPANFPHVTPNLPPPPALR-------- 308
Query: 956 KYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGR----PAKNKRRKLAP 1003
P N+++S + +P P +P P G P K LAP
Sbjct: 309 ---PLNNASASPPGLGAQPLP---GHLPSPHAMGQGMGGLPPGPEKGPTLAP 354
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 106 bits (265), Expect = 1e-22
Identities = 153/553 (27%), Positives = 200/553 (36%), Gaps = 112/553 (20%)
Query: 146 RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPV--PSGGSSS--- 200
+P PPTT + G G+ P P + P L+ G PPR + PS G SS
Sbjct: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589
Query: 201 -PRFLPRGNAPSPA------PPPPPAI-SLNAPSYNWGAALRSSLVP-SDLGSPPAPHAS 251
P P+G A PA PP P + SL +P GA++ SSL S PAP
Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSP----GASVSSSLTSLCSSSSDPAPSDR 645
Query: 252 SSPPSDPPLFHCSDALTPPPLP--PSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPT 309
S P PL D PP P P+ P P S P + A +V GP+ + T
Sbjct: 646 SGPQILTPL---GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV--STT 700
Query: 310 VEGPGAPPFLASSLLS-----AAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQR 364
P +PP ++L +K Q PP PP + P + P + PS
Sbjct: 701 DASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA---PSAS 757
Query: 365 RPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS 424
P Q P P PAP Q S+ + P + + +P P+
Sbjct: 758 ETAEEPL----------QDPNWPPPPPPAPEEQDLSMAD----FPPPEEAFFSVASPEPA 803
Query: 425 HSDGSFNLLGSDAHLPPPPTLSS----GSPPQPRHPIQPSLPGTTSGSLSSVP------- 473
GS L+ S A T GSP P P P+ + G ++ +P
Sbjct: 804 GPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGC 863
Query: 474 --GAPAPPAASKAPVVPSPVLQSP---SEGLGMGA-----GPACPLPPLA---GGEAFPF 520
G P AP+V +LQ S G GA GP+ P PL G A P
Sbjct: 864 SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPV 923
Query: 521 PSPEQGL-------ALSGAGFPGMLGALPL--PLSLGQPPPSPL---------------- 555
P+P GL A S A G+ A P P + +PP SP
Sbjct: 924 PAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQL 983
Query: 556 -----------LNHSLFGVLTGGGGQPPPE-----PLLPPPGGPGPPLAPGEPEGPSLLV 599
L +L L Q PP+ P PPP P + P PS
Sbjct: 984 ERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPR 1043
Query: 600 ASLLPPPPSDLLP 612
A L PP++ LP
Sbjct: 1044 AEPLTAPPTNGLP 1056
Score = 95.1 bits (235), Expect = 3e-19
Identities = 201/807 (24%), Positives = 273/807 (33%), Gaps = 174/807 (21%)
Query: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS----QAFPTLAGPGGLFPPRLADP 192
T + PP RP P L GG G P P++S + + P + PP +
Sbjct: 310 TGTRAPPLTRPMSLAVPG--LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTV--D 365
Query: 193 VPSGGSSSPRFLPRGNAPSPAP--------------PPPPAISLNAPSYNWGAALRSSLV 238
V + G S R L R + S +P P P + ++ S W + S +
Sbjct: 366 VVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTI 425
Query: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQ----------- 287
SD + + S P S+++ PPP S G ++
Sbjct: 426 VSDGSTLSSKGGSEGQPESST---ASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482
Query: 288 -----------------PPVSSATMH---LPLVLGPLGGAPTVEG---PGAPPFLASSLL 324
PP + ++H L + GPLG P E P P +
Sbjct: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542
Query: 325 SAAAKAQHPPLPPPSTLQG-------RRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLE 377
A A PP P S + G R PR+ + S SS P PP + L
Sbjct: 543 EGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP---KGLA 599
Query: 378 GRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT-PGPSHSDGSFNL--LG 434
G P +P +++P P V SL P + S+ SL + P PS G L LG
Sbjct: 600 GP-PASPGKAQPPKPERVT---SLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG 655
Query: 435 SDAHLPPPPTLSSGSPPQPRHPIQP-------SLPGTTSGSLSSV---PGAPAPPAASKA 484
+PP P + + P P P P + P G +S+ P +P P +
Sbjct: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT 715
Query: 485 PVVPSPVL---QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGAL 541
P+ SPV+ QSP P P PP P PE + A
Sbjct: 716 PLQESPVISKDQSP---------PPSP-PPSYHPPPPPTKKPEVVVEAPSA---SETAEE 762
Query: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL-----PPPGGP-GPPLAPGEPEGP 595
PL PPP P + PPPE P P GP G P P
Sbjct: 763 PLQDPNWPPPPPPAPEEQDLSM----ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Query: 596 SLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSG 655
S +L PP PPP APP+ AS P G A + G G P
Sbjct: 819 SSSATALQIQPPGSPDPPP-APPAPAPASSAP----GHVAKLPQKEPVGCSKGGGPPRED 873
Query: 656 LGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATT 715
+G +PL+ P L ++ L S + P G P SAPQ
Sbjct: 874 VG--APLVTPSLL---QMVRLRS------VGAPGGAPTPALGPSAPQ------------- 909
Query: 716 DPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGL 775
L +A S P S L A++ SL +S G S QP GP
Sbjct: 910 ----KPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGL--SSAQPNGP-------- 955
Query: 776 QLLPGGGAPPPLSEASSPLACLLQ-SLQIPPEQPEAP---------------CLPPESPA 819
P PP S AS+ + S ++ E+P +P + + P
Sbjct: 956 ---PEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP 1012
Query: 820 SALEPEPARPPLSALAPPHGSPDPPVP 846
A + P PP A P G P P P
Sbjct: 1013 QAPKKSPKAPPPVARKPSVGVPPPASP 1039
Score = 78.6 bits (192), Expect = 3e-14
Identities = 123/492 (25%), Positives = 165/492 (33%), Gaps = 115/492 (23%)
Query: 81 PVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMF----- 135
P +PG A P E +T L R ++++ S+ ++ S +P + + PQ+
Sbjct: 602 PASPGKAQ--PPKPERVTSL---RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGD 656
Query: 136 HTVSPGPPSARPPCRVPPTTPLNGGPGS-------LPPEPPSVSQAFP-TLAGPGGLFPP 187
V P P P PP+ P + P + + P P S + A P + P P
Sbjct: 657 RFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716
Query: 188 RLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
PV S S P P P P P P + + APS S A
Sbjct: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS----------------ASETA 760
Query: 248 PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHL--PLVLGPLG 305
P PP PPP P +L A PP A + P GP G
Sbjct: 761 EEPLQDPNWPPP---------PPPAPEEQDLSM----ADFPPPEEAFFSVASPEPAGPSG 807
Query: 306 GAPTVEGPGAPPFLASSLLSAAAKAQHP--PLPPPSTLQGRRPRAQAPSASHSSSLRPSQ 363
V P A SS + A + Q P P PPP+ P A AP++S +
Sbjct: 808 SPELVSSPAA-----SSSSATALQIQPPGSPDPPPA------PPAPAPASSAPGHVA--- 853
Query: 364 RRPRRPPTVFRLLEGRGP---------------QTPRRSRPRAPAPVPQPFSLPEPSQPI 408
+ P++ P +G GP Q R AP P P P Q
Sbjct: 854 KLPQKEPV--GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP 911
Query: 409 LPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP--PQPRHPIQPSLPGTTS 466
L LS P P PS + L + L LSS P P P P P +T+
Sbjct: 912 LRRALSGRASPVPAPSSGLHAAVRLKA-CSLAASEGLSSAQPNGPPEAEPRPPQSPASTA 970
Query: 467 G------------------------------SLSSVPGAPAPPAASKAPVVPSPVLQSPS 496
L S+ P A K+P P PV + PS
Sbjct: 971 SFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS 1030
Query: 497 EGLGMGAGPACP 508
G+ A P+ P
Sbjct: 1031 VGVPPPASPSYP 1042
Score = 65.1 bits (157), Expect = 3e-10
Identities = 112/445 (25%), Positives = 154/445 (34%), Gaps = 68/445 (15%)
Query: 446 SSGSPPQPR--HPIQPSLPGTTSGS----------LSSVPGAPAPPAASKAPVVPSPVLQ 493
SS S PQPR HP S + S S LSS G+ P +S A + V+
Sbjct: 397 SSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS---NSVVP 453
Query: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
P G G G+ P G A E LS + G L +PPP
Sbjct: 454 PPQGGSGRGS-------PSGGSTA------EASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500
Query: 554 PLLNHSL----FGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSD 609
P HSL V G G PP P P PP G EG A+ PP P++
Sbjct: 501 PRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS-EGAG---AAPCPPNPAN 556
Query: 610 LLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA------EGAGGPSGEPFSGLGDLSPLL 663
P +P + P L P++G S +G GP P
Sbjct: 557 SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ------- 609
Query: 664 FPPLSAPPTLIALNSALLAATLDP--PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASS 721
PP T + A ++++L S + P P S PQ P P +
Sbjct: 610 -PPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668
Query: 722 LGKAPSNSGRPPQLLSPLLGASLL--GDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLP 779
P + R P +P L A + G +S+ +SP + P+ PL + +
Sbjct: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728
Query: 780 GGGAPPP--------------LSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPE 825
+PPP + EA S + LQ P P P P E S +
Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788
Query: 826 PARPPLSALAPPHGSPDPPVPELLT 850
P ++A P + PEL++
Sbjct: 789 PPEEAFFSVASPEPAGPSGSPELVS 813
Score = 34.7 bits (78), Expect = 0.46
Identities = 46/181 (25%), Positives = 64/181 (35%), Gaps = 14/181 (7%)
Query: 823 EPEPARPPLSALAPPHGSPDPPVPEL-LTGRGSGKRGRRGGGGLRGINGEARPARGRKPG 881
+PE + S + PP G P T S R G L G + R + P
Sbjct: 441 QPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500
Query: 882 SRREPGR----LALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSE 937
RR LA+ G G + P R Q GG+E P P+
Sbjct: 501 PRRTHSLHQRGLAVPDGPLG-----LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPA 555
Query: 938 DLKVP---PGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
+ VP PG R+ R R +P+ +S TL P A P +A+P +P
Sbjct: 556 NSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS-PGKAQPPKPE 614
Query: 995 K 995
+
Sbjct: 615 R 615
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 105 bits (263), Expect = 2e-22
Identities = 182/691 (26%), Positives = 247/691 (35%), Gaps = 163/691 (23%)
Query: 116 SMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAF 175
SM + P P++ + PS PP PP P P PP PP SQ+
Sbjct: 597 SMNRPYTSLVPPLSPQPKIVTPYTASQPS--PPLPPPPPPPPPPPPPPPPPPPPLPSQSA 654
Query: 176 PTL--AGP------------------GGLFPPRLADPVPSGGSSSPRFL--PRGNAPSPA 213
P+ A P G LF P PV S P+ L P G P P
Sbjct: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPP-TPPVMQSQSVKPQILVPPNGVVPPP- 712
Query: 214 PPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALT--PPP 271
PPPPP + G+A+ + L P+ +P P S+ PP P H +T PP
Sbjct: 713 PPPPPPPTP-------GSAM-AQLKPAPC-APSLPQFSAPPP--PLKIHQVQHITQVAPP 761
Query: 272 LPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQ 331
PP P P PA PP + PLV T+ P + +A + AA
Sbjct: 762 TPP----PPPPIPAPLPPQAPPK---PLV--------TIPAPTSTKTVAPVVTQAAPPTP 806
Query: 332 HPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRA 391
PP+PP A+ A +S + PS PPT
Sbjct: 807 TPPVPP----------AKKQPAFPASYIPPS------PPT-------------------P 831
Query: 392 PAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPP 451
P PVP P LP S P P P S + + PPPPT
Sbjct: 832 PVPVP---------PPTLPKQQSFCAKPPPSPLSPVPSV-VKQIASQFPPPPT------- 874
Query: 452 QPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPV-VPSPVLQSPSEGLGMGAGPACPLP 510
P QP P + + S P A P + + VPSP P + P P P
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 511 PLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQ 570
A P P P +G PG + +PPP+P N S + + G +
Sbjct: 935 VPAPP---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS---IKSSSGAE 988
Query: 571 PPPEPLLPPPGGPGPPLAPGEPEGPSL--LVASLLPP-----PPSDLLPPPSAPPS---- 619
P EP+ PS+ LV+ PP P + LPPP+APP
Sbjct: 989 HP------------------EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Query: 620 NLLASFLP-------LLALGPT-AGDGEGS-AEGAGGPSGEPFSGLGDLSPLLFPPLSAP 670
NL LP + A P +G G+ S E PS F + L PP+
Sbjct: 1031 NLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEI- 1089
Query: 671 PTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG 730
P + + N++ A ++P P Q +S + PPT +T + + + P+ +
Sbjct: 1090 PAVFSGNTSPKVAVVNP---QPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT 1146
Query: 731 RPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
PQ+ + SSL+ PG L L
Sbjct: 1147 VVPQVPT--------SPKSSLSVQPGFLADL 1169
Score = 91.3 bits (225), Expect = 4e-18
Identities = 182/733 (24%), Positives = 259/733 (35%), Gaps = 159/733 (21%)
Query: 235 SSLVPSDLGSPP--APHASS--SPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPV 290
+SLVP P P+ +S SPP PP PPP PP P P P PP+
Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPP---------PPPPPP----PPPPPPPPPPPL 649
Query: 291 SSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKA-QH------PPLPPPSTLQG 343
S + AP+ G AP F+ S ++ A QH PP PP Q
Sbjct: 650 PSQS------------APSA-GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS 696
Query: 344 RRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE 403
+P+ P + + P P PPT + P S P+ AP P P + +
Sbjct: 697 VKPQILVPP----NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP-PPPLKIHQ 751
Query: 404 PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQ-PRHPIQPSLP 462
++ + PTP PPPP + + PPQ P P+
Sbjct: 752 VQH------ITQVAPPTP------------------PPPPPIPAPLPPQAPPKPLVTIPA 787
Query: 463 GTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522
T++ +++ V APP + P VP P + P A PA +PP P P
Sbjct: 788 PTSTKTVAPVVTQAAPPTPT--PPVP-PAKKQP-------AFPASYIPPSPPTPPVPVPP 837
Query: 523 PEQGLALSGAGFPGMLGALPLPLSLGQ------PPPSP--LLNHSLFGVLTGGGGQPPPE 574
P S P P+P + Q PPP+P + + L V Q PP
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 575 PLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPT 634
P P P P +SL+ PPP P PP AS P + P
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Query: 635 AGDGEGSAEGAGGPSGEP--FSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692
+ S+ G P P S + S P P +++S + T SG+P
Sbjct: 958 KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP----SVDSLVSKFTPPAESGSP 1013
Query: 693 PQPCVLSAPQPGPPTSSVTTATTDPGASSLG----KAPSNSGR----------------- 731
+ + P P + PG G KAP SGR
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDF 1073
Query: 732 ---PPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLS 788
PP+ PL + S TS A+ + P P ++ ++ APPP
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSGNTSPKVAVVN----PQPQQWSKMSVK-----KAPPPTR 1124
Query: 789 EASSPLACLLQSLQIPPEQPEAPCLP--PESPASALEPEPA----------RPPLS---- 832
+ L Q+ +I + A +P P SP S+L +P R ++
Sbjct: 1125 PKRNDSTRLTQA-EISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGS 1183
Query: 833 -----ALAPPHGSPD-----PPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPG- 881
+ A P + D PP PELL+ + ++ G G I+G A RG P
Sbjct: 1184 LSSRMSRAEPTATMDDMALPPPPPELLSDQ------QKAGYGGSHISGYATLRRGPPPAP 1237
Query: 882 -SRREPGRLALKW 893
R + +L+ W
Sbjct: 1238 PKRDQNTKLSRDW 1250
Score = 78.2 bits (191), Expect = 4e-14
Identities = 139/580 (23%), Positives = 195/580 (33%), Gaps = 118/580 (20%)
Query: 456 PIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGG 515
P+ P P + +S P P PP P P P P P PPL
Sbjct: 608 PLSPQ-PKIVTPYTASQPSPPLPPPPPPPPPPPPP--------------PPPPPPPLPSQ 652
Query: 516 EAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEP 575
A P + + + + A +L +PP P++ P+
Sbjct: 653 SA-PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ----------SVKPQI 701
Query: 576 LLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL-LASFLPLLALGPT 634
L+PP G PP P P P +A L P P + LP SAPP L + + + P
Sbjct: 702 LVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP 761
Query: 635 AGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDP------- 687
P P P PP + P L+ + + T+ P
Sbjct: 762 TP-----------PPPPPI-------PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Query: 688 PSGTPPQPCVLSAPQ-------PGPPTSSVTTAT-TDPGASSLGKAPSNSGRPPQLLSPL 739
P+ TPP P P P PPT V T P S P PP LSP+
Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP-----PPSPLSPV 858
Query: 740 LGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAP--PPLSEASSPLACL 797
S++ ++S P P++ P L+ +P AP PP +A
Sbjct: 859 --PSVVKQIASQFPPPPTPPAMESQP---------LKPVPANVAPQSPPAVKAKPKW--- 904
Query: 798 LQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKR 857
Q IP P+ P PPES S + P P PP APP P PP T SG
Sbjct: 905 -QPSSIPVPSPDFPPPPPES--SLVFPPP--PPSPVPAPP---PPPPPTASPTPDKSGSP 956
Query: 858 GRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRR-------- 909
G+ + ++ PG ++ P + +G P+R
Sbjct: 957 GK-------------KTSKTSSPGGKKPPPTPQRNSSIKSS-SGAEHPEPKRPSVDSLVS 1002
Query: 910 --THHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNS-- 965
T + E P PP PG + PGV+++ + R +S
Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062
Query: 966 ---SRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLA 1002
S + P P +PLPP P + N K+A
Sbjct: 1063 EFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 103 bits (257), Expect = 8e-22
Identities = 232/904 (25%), Positives = 308/904 (34%), Gaps = 196/904 (21%)
Query: 137 TVSPGPPSARPPCRVP--------PTTPLNGGPGSLPPEPPSVSQ-----AFPTLAGPGG 183
T +P P +A+P ++ PT P +P + P +Q +F A P
Sbjct: 345 TRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQ 404
Query: 184 LFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPP-----PAISLNAPSYNWGAALRSSLV 238
P + PVP+ S + N P PPPP P + ++ A + +
Sbjct: 405 KQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKI 464
Query: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298
S P + S+ P PP AL+ P P + + PA+ P +S T
Sbjct: 465 TSHASKPASARTSTHKP--PPF----TALSSSPAPTPGSTRSTRPPATMVPPTSGT---- 514
Query: 299 LVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAP-SASHSS 357
AP V PG+ P + + + A + P P R+P P A+
Sbjct: 515 ---STPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSP-----RKPVPLRPGKAARDV 566
Query: 358 SLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQP----FSLPEPSQPILPSVL 413
L RP P+ P+ S+ PA V P S P P+ S+
Sbjct: 567 PLSDLTTRP-------------SPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGY-SIF 612
Query: 414 SLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTS-----GS 468
L G TP P L+G PP P G P P P P +PG G
Sbjct: 613 HLAG-STPFPL-------LMG-----PPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGP 659
Query: 469 LSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528
+ PG P PP A P SP + GA LP L+G P P +G
Sbjct: 660 YGN-PGLPGPPGAKGQKGDPG---LSPGKAHD-GAKGDMGLPGLSGN---PGPPGRKG-- 709
Query: 529 LSGAGFPGMLGALPLPLSLGQPPP--SPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPP 586
G+PG G P GQP P SP G G P + L P G PGP
Sbjct: 710 --HKGYPGPAGH---PGEQGQPGPEGSP-----------GAKGYPGRQGLPGPVGDPGPK 753
Query: 587 LAPGEPEGPSLLVASLLPPPPSDL-LPPPSAPPSNLLASFLPLL--ALGPTAGDGEGSAE 643
+ G P L LP + LP + P + GP DG
Sbjct: 754 GSRGYIGLPGLFG---LPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL 810
Query: 644 GAGGPSGEP--FSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
G GP G P LG L P+ +P P + L ++ L G P V P
Sbjct: 811 GLPGPPGVPGLIGDLGVLGPIGYP---GPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDP 867
Query: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSL----TSSPGA 757
D G+ L P G+P L +GD S+ P
Sbjct: 868 ----------GFQGDKGSQGLPGFPGARGKPGPL-------GKVGDKGSIGFPGPPGPEG 910
Query: 758 LPSLLQPPGPLLSGQLGLQLLPGG-GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPE 816
P + PPG +G G++ PG G P P Q+ PE E P PP
Sbjct: 911 FPGDIGPPGD--NGPEGMKGKPGARGLPGPRG-------------QLGPEGDEGPMGPPG 955
Query: 817 SPASALEPE----PARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEA 872
+P +P P RP L + G P P P G++G G GL G
Sbjct: 956 APGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP-------VGEQGFMGFIGLVG----- 1003
Query: 873 RPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPP 932
EPG + K G RG P+ + H G + G P +P P
Sbjct: 1004 ------------EPGIVGEK-GDRGMMGPPGVPGPKGS--MGHPG-MPGGMGTPGEPGPQ 1047
Query: 933 GPHSEDLKVPPGV-VRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPG 991
GP + PPG+ K RRG R P S P P+ RPG
Sbjct: 1048 GPPGS--RGPPGMRGAKGRRGPRGPDGPAGEQGS------------RGLKGPPGPQGRPG 1093
Query: 992 RPAK 995
RP +
Sbjct: 1094 RPGQ 1097
Score = 77.0 bits (188), Expect = 8e-14
Identities = 228/893 (25%), Positives = 291/893 (32%), Gaps = 185/893 (20%)
Query: 142 PPSARPPC-RVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS-- 198
P SAR + PP T L+ P P S + G PR A VP+ GS
Sbjct: 471 PASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAP 530
Query: 199 ----------SSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAP 248
+S + P+ + P P P + + P SDL + P+P
Sbjct: 531 TGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPL-------------SDLTTRPSP 577
Query: 249 HASSSPPSDPPLFHCSDA--LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGG 306
P + A L+ P P S+ S P PL++GP G
Sbjct: 578 RQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTP--------FPLLMGPPGP 629
Query: 307 APTVEGPGAPPFLASSLLSAAAKAQHPPLP--------PPSTLQGRRPRAQAPSASHSSS 358
PG P + A + PP P PP + +P +H +
Sbjct: 630 KGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGA 689
Query: 359 LRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSL--- 415
+ P L G R+ P P P +P P
Sbjct: 690 -KGDMGLPG--------LSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGR 740
Query: 416 LGLP----TPGPSHS------DGSFNLLGSDAH--LP--PPPTLSSGSPPQP-----RHP 456
GLP PGP S G F L GSD LP P G P P R P
Sbjct: 741 QGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGP 800
Query: 457 IQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGE 516
P L G G L +PG P P V P+ +G+ G + P L G +
Sbjct: 801 --PGLDG-NPGEL-GLPGPPGVPGLIGDLGVLGPIGYPGPKGM-KGLMGSVGEPGLKGDK 855
Query: 517 AFPFPSPEQGL-ALSG-AGFPGMLGALPLPLSLG-QPPPSPLLNHSLFGVLTGGGGQPPP 573
EQG+ +SG GF G G+ LP G + P PL G + G G P P
Sbjct: 856 G------EQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI-GFPGPPGP 908
Query: 574 EPL---LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLP--------PPSAP----- 617
E + PPG GP G+P A LP P L P PP AP
Sbjct: 909 EGFPGDIGPPGDNGPEGMKGKPG------ARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962
Query: 618 PSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEP----FSGL----GDLSPLLFPPLSA 669
P P G GE G GP GE F GL G + +
Sbjct: 963 PGRKGFPGRP----GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018
Query: 670 PPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDP----------G 718
PP + ++ + GTP +P P GPP P G
Sbjct: 1019 PPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQG 1078
Query: 719 ASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778
+ L P GRP + + G+ L S P + PGP SG G + L
Sbjct: 1079 SRGLKGPPGPQGRPGRPGQ----QGVAGERGHLGSR--GFPGI---PGP--SGPPGTKGL 1127
Query: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838
PG P P + + PP P LP E+ P L
Sbjct: 1128 PGEPGPQGPQGPIGPPGEM--GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR 1185
Query: 839 GSP------DPPVPELLTG-RG----SGKRGRRGGGGLRGINGEARP-----ARG--RKP 880
G P P P+ L G RG G+ G +G GL G +G P RG K
Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245
Query: 881 GSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG 933
G + E GR K G +G + G+L E G P DP PPG
Sbjct: 1246 GKQGEKGRTGAK-GAKG-----------------YQGQLGEMGV-PGDPGPPG 1279
Score = 73.9 bits (180), Expect = 7e-13
Identities = 272/1042 (26%), Positives = 346/1042 (33%), Gaps = 217/1042 (20%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRK-AVAMATLYRSMETTCSHSSPGEGASPQMFH 136
PL P T P K+ +H K A A + ++ T SSP +P
Sbjct: 442 PLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSP----APTPGS 497
Query: 137 TVSPGPPSARPP----CRVPPTTPLNGGPGSLPP--EPPSVSQAFPTLAGPGGLFPPRLA 190
T S PP+ P P T P PGS P + P S+A AGP PR
Sbjct: 498 TRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKK-AGPKS--SPR-- 552
Query: 191 DPVPSGGSSSPRFLPRGNA---PSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
PVP + R +P + PSP P P S L PA
Sbjct: 553 KPVPLRPGKAARDVPLSDLTTRPSPRQPQP-----------------SQQTTPALVLAPA 595
Query: 248 PHASSSP---PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPL 304
SSSP S +FH + + TP PL L PGP + P L L
Sbjct: 596 QFLSSSPRPTSSGYSIFHLAGS-TPFPL-----LMGPPGPKGDCGLPG-----PPGLPGL 644
Query: 305 GGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRR-PRAQAPSASHSSSLRPSQ 363
G P GP PP +P LP P +G++ +P +H + +
Sbjct: 645 PGIPGARGPRGPP----------GPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGA-KGDM 693
Query: 364 RRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSL---LGLP- 419
P L G R+ P P P +P P GLP
Sbjct: 694 GLPG--------LSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPG 745
Query: 420 ---TPGPSHS------DGSFNLLGSDAH--LPPPPTLSS--GSPPQP-----RHPIQPSL 461
PGP S G F L GSD LP P G P P R P P L
Sbjct: 746 PVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGP--PGL 803
Query: 462 PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFP 521
G G L +PG P P V P+ +G+ G + P L G +
Sbjct: 804 DGNP-GELG-LPGPPGVPGLIGDLGVLGPIGYPGPKGM-KGLMGSVGEPGLKGDKG---- 856
Query: 522 SPEQGL-ALSG-AGFPGMLGALPLPLSLG-QPPPSPLLNHSLFGVLTGGGGQPPPEPL-- 576
EQG+ +SG GF G G+ LP G + P PL G + G G P PE
Sbjct: 857 --EQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI-GFPGPPGPEGFPG 913
Query: 577 -LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLP--------PPSAP-----PSNLL 622
+ PPG GP G+P A LP P L P PP AP P
Sbjct: 914 DIGPPGDNGPEGMKGKPG------ARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKG 967
Query: 623 ASFLPLLALGPTAGDGEGSAEGAGGPSGEP----FSGL----GDLSPLLFPPLSAPPTLI 674
P G GE G GP GE F GL G + + PP +
Sbjct: 968 FPGRP----GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVP 1023
Query: 675 ALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDP----------GASSLG 723
++ + GTP +P P GPP P G+ L
Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLK 1083
Query: 724 KAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPL-LSGQLGLQ-----L 777
P GRP + + A G L S PG +P PPG L G+ G Q +
Sbjct: 1084 GPPGPQGRPGRPGQQGV-AGERGHLGS-RGFPG-IPGPSGPPGTKGLPGEPGPQGPQGPI 1140
Query: 778 LPGG-----GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLS 832
P G G P + E P ++ P P L + LE +
Sbjct: 1141 GPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPD 1200
Query: 833 ALAPPHGSPDP------------------PVPELLTG-RG----SGKRGRRGGGGLRGIN 869
L G P P P P +TG RG SGK+G +G G +G
Sbjct: 1201 GLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAK 1260
Query: 870 G-EARPARGRKPGSRREPGRLALKWGTRG-----GFNGQM--ERSPRRTHHWQHNG---- 917
G + + PG PG K G+RG G G+M + P + H G
Sbjct: 1261 GYQGQLGEMGVPGDPGPPGTPGPK-GSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGP 1319
Query: 918 --------ELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQD 969
E E G + K PPGP + + P G R R +P Q
Sbjct: 1320 LGPPGPKGEKGEQGEDGKAEGPPGPPGD--RGPVG----DRGDRGEPGDPGYPGQEGVQG 1373
Query: 970 ITLEPSPTARAAVPLPPRARPG 991
+ +P + P PR PG
Sbjct: 1374 LRGKPGQQGQPGHP-GPRGWPG 1394
Score = 63.2 bits (152), Expect = 1e-09
Identities = 209/872 (23%), Positives = 265/872 (30%), Gaps = 178/872 (20%)
Query: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSG-- 196
+PGPP + P G G PE ++ +P G P + DP P G
Sbjct: 701 NPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQG----LPGPVGDPGPKGSR 756
Query: 197 ------------GSSSPRFLP-----RGNAPSPAPPP------PPAISLNAPSYNWGAAL 233
GS R LP RG P P PP + N
Sbjct: 757 GYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGN---------- 806
Query: 234 RSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS- 292
P +LG P PP P L L P P + G +P +
Sbjct: 807 -----PGELGLP-------GPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGD 854
Query: 293 -ATMHLPLVLGPLGGAPTVEGPGAPPFLAS-------SLLSAAAKAQHPPLPPPSTLQGR 344
+P V G G G P F + + P P P G
Sbjct: 855 KGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGD 914
Query: 345 --RPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLP 402
P P +P R P GP P P AP QP
Sbjct: 915 IGPPGDNGPEGMKG---KPGARGLPGPRGQLGPEGDEGPMGP----PGAPGLEGQPGRKG 967
Query: 403 EPSQPILPSVLSLLGLP-TPGPSHSDGSFNLLG-----------SDAHLPPPPTL----- 445
P +P L V G P PGP G +G D + PP +
Sbjct: 968 FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG 1027
Query: 446 SSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGP 505
S G P P P PG PG+ PP A P + P G
Sbjct: 1028 SMGHPGMPGGMGTPGEPGP-----QGPPGSRGPPGMRGAKGRRGP--RGPDGPAGEQGSR 1080
Query: 506 ACPLPPLAGGEAFPFPSPEQGLA-----LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSL 560
PP G + P +QG+A L GFPG+ G P + G P
Sbjct: 1081 GLKGPP--GPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP---------- 1128
Query: 561 FGVLTGGGGQPPPEPLLPPPG--GP-GPPLAPGEP--EGPSLLVASLLP---PPPSDLLP 612
G G P+ + PPG GP GPP A GEP G + + L P P L+
Sbjct: 1129 -----GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIG 1183
Query: 613 PPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFS----GL----GDLSPLLF 664
P + GP DG G GP GE GL G P
Sbjct: 1184 QRGEPGLEGDS--------GPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGV 1235
Query: 665 PPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP-QPGPPTSSVTTATTDPGASSLG 723
+ P G Q + P PGPP + PG
Sbjct: 1236 TGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT--------PGPKGSR 1287
Query: 724 KAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGA 783
+ +G P ++ GA L+ G + L PPGP G+ G Q G
Sbjct: 1288 GSLGPTGAPGRM-----GAQGEPGLAGYDGHKGIVGPL-GPPGP--KGEKGEQGEDGKAE 1339
Query: 784 PPPLSEAS-SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPD 842
PP P+ + +P P P + L +P + P G P
Sbjct: 1340 GPPGPPGDRGPVGD-----RGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394
Query: 843 PPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQ 902
P + G GK+G+ G G RG+ G +G PG R GR L+ G G
Sbjct: 1395 PKGSKGAEGP-KGKQGKAGAPGRRGVQG----LQG-LPGPRGVVGRQGLE-----GIAGP 1443
Query: 903 MERSPRRTHHWQHNGELAEGGAEPKDPPPPGP 934
+ P R GE + G DP P GP
Sbjct: 1444 -DGLPGRDGQAGQQGEQGDDG----DPGPMGP 1470
Score = 60.5 bits (145), Expect = 8e-09
Identities = 126/482 (26%), Positives = 163/482 (33%), Gaps = 88/482 (18%)
Query: 489 SPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLG 548
+P L S G G G P P P +P Q +A+ G P LP LS
Sbjct: 276 TPALGSLPAGRGP-RGTVAPATPTKPQRTSP-TNPHQHMAVGG---PAQTPLLPAKLSAS 330
Query: 549 QPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPG-----PPLAPGEPEGPSLLVASLL 603
P+L S+ GG P P P P P +P PS + +
Sbjct: 331 NAL-DPMLPASV------GGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIK 383
Query: 604 PPPPSDLLPPPSAPPSNLLASFLPLLALGPTAG---------DGEGSAEGAGGPSGEPFS 654
P P+ PS+ S LP P E + G P
Sbjct: 384 SPHPTQ-----KTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPP 438
Query: 655 GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGT-----PPQPCVLS---APQPG-- 704
L P PTL + + + P S PP LS AP PG
Sbjct: 439 STRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGST 498
Query: 705 ----------PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSS 754
PPTS +T T P + G AP+ S +P +G +S +
Sbjct: 499 RSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKP------------IGSEASKKAG 546
Query: 755 PGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP 814
P + P + P PL G+ + PLS+ L Q P Q P L
Sbjct: 547 PKSSP---RKPVPLRPGKAARDV--------PLSD----LTTRPSPRQPQPSQQTTPAL- 590
Query: 815 PESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRG-SGKRGRRGGGGLRGING--E 871
+PA L P RP S + H + P P L+ G G G G GL G+ G
Sbjct: 591 VLAPAQFLSSSP-RPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPG 649
Query: 872 ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPP 931
AR RG PG PG L G +G G SP + H G++ G +P P
Sbjct: 650 ARGPRG-PPGPYGNPG-LPGPPGAKGQ-KGDPGLSPGKAHDGA-KGDMGLPGLS-GNPGP 704
Query: 932 PG 933
PG
Sbjct: 705 PG 706
Score = 57.0 bits (136), Expect = 9e-08
Identities = 207/852 (24%), Positives = 258/852 (30%), Gaps = 176/852 (20%)
Query: 140 PGPPSARPPCRVPPTTPLNGGPGS--LPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGG 197
PGP +R +P L G G LP P + + PG FP + P G
Sbjct: 750 PGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK----MGMPG--FPGVFGERGPPGL 803
Query: 198 SSSPRFLPRGNAPSPAPPPPPAI--------SLNAPSYNWGAALRSSL----VPSDLGSP 245
+P G P PP P + + P L S+ + D G
Sbjct: 804 DGNP-----GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQ 858
Query: 246 PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQP-PVSSA----TMHLPLV 300
P S P S LP PG +P P+ ++ P
Sbjct: 859 GVPGVSGDPGFQGD-------------KGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP 905
Query: 301 LGPLG-----GAPTVEGP----GAPPF--LASSLLSAAAKAQHPPLPPPST--LQGRRPR 347
GP G G P GP G P L + P+ PP L+G+ R
Sbjct: 906 PGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGR 965
Query: 348 AQAPSASHSSSLRPSQRRPRRPPTV-------FRLLEGRGPQTPRRSRPRAPAPVPQPFS 400
P ++ P RP V F L G + P P
Sbjct: 966 KGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGP 1025
Query: 401 LPEPSQPILPSVLSLLGLPTP-GPSHSDGSFNLLGSDAHL----PPPPTLSSGS-----P 450
P +P + G P P GP S G + G+ P P GS P
Sbjct: 1026 KGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGP 1085
Query: 451 PQPR-HPIQPSLPGTTS--GSLSS-----VPGAPAPPAASKAPVVPSPVLQSPSEGLGMG 502
P P+ P +P G G L S +PG PP P P P Q P +G
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGP--QGPQGPIGPP 1143
Query: 503 A--GPACP--------LPPLAG--GEAFPFPSP-EQGLALSGAGFPGM------LGALPL 543
GP P LP AG G+ P +P EQGL + G PG+ +G L
Sbjct: 1144 GEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL-IGQRGEPGLEGDSGPMGPDGL 1202
Query: 544 PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGE--PEGPS----- 596
G P P G G+ E L+ G PGPP G PEG S
Sbjct: 1203 KGDRGDPGPD------------GEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250
Query: 597 --------------LLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA 642
L +P P PP + P S LGPT G A
Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPG---PPGTPGPKGSRGS------LGPTGAPGRMGA 1301
Query: 643 EGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQ 702
+G G +G + G + L PP PP P +
Sbjct: 1302 QGEPGLAG--YDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGE 1359
Query: 703 PGPP----TSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPG-- 756
PG P V PG P G P S GA +PG
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSK--GAEGPKGKQGKAGAPGRR 1417
Query: 757 ALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPE 816
+ L PGP G +G Q L G P L + P P
Sbjct: 1418 GVQGLQGLPGP--RGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG 1475
Query: 817 SPASALEPEPARPP-LSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPA 875
+P A P PP + G PP GKRG G GL G GE
Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPP----------GKRGTEGRTGLPGNQGE---- 1521
Query: 876 RGRKPGSRREPG 887
PGS+ +PG
Sbjct: 1522 ----PGSKGQPG 1529
Score = 41.2 bits (95), Expect = 0.005
Identities = 125/516 (24%), Positives = 165/516 (31%), Gaps = 105/516 (20%)
Query: 141 GPPSARPPCRVPPTTPLNG--GPGSLPPEPPSVSQ-AFPTLAGPGGLFPPR-----LADP 192
GPP A +P + G GP P E + Q P L G G P DP
Sbjct: 1150 GPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209
Query: 193 VPSGGSSSPRFLPRGNAPSPAPPPPPAIS-LNAPSYNWG--------AALRSSLVPSDLG 243
P G G PP PP ++ + P G A + LG
Sbjct: 1210 GPDGEHGEKG--QEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLG 1267
Query: 244 SPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP 303
P PP P +L P P G +P ++ H +V GP
Sbjct: 1268 EMGVP-GDPGPPGTPGPKGSRGSLGP------TGAPGRMGAQGEPGLAGYDGHKGIV-GP 1319
Query: 304 LGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPP----PSTLQGRRPRAQAPSASHSSSL 359
LG PG P KA+ PP PP P +G R P +
Sbjct: 1320 LGP------PG--PKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGV 1371
Query: 360 -----RPSQR-RPRRP-PTVFRLLEG-RGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPS 411
+P Q+ +P P P + +G +G + P+ + +A AP +
Sbjct: 1372 QGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRR-------------G 1418
Query: 412 VLSLLGLPTP-------GPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI-QPSLPG 463
V L GLP P G G L G D P P P + PG
Sbjct: 1419 VQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPG 1478
Query: 464 TTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523
++ +PGA PP +P + G G L G + P
Sbjct: 1479 -----VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTG-------LPGNQGEPGSKG 1526
Query: 524 EQGLALSGAGFPGMLGALPL---PLSLG-------QPPPSPLLNHSLFGVL--TGGGGQP 571
+ G + GFPGM G P +G + PP + + G L G G P
Sbjct: 1527 QPGDS-GEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLP 1585
Query: 572 PPEP---------LLPPPGGPGP---PLAPGEPEGP 595
P+ L P G PGP P PG P GP
Sbjct: 1586 GPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 102 bits (253), Expect = 2e-21
Identities = 229/902 (25%), Positives = 286/902 (31%), Gaps = 199/902 (22%)
Query: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSS 199
PGPP + P +P + G G P L G GL P P P G
Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGL-PGENGAPGPMGPRG 303
Query: 200 SP--RFLP--------------RGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLG 243
+P R P RG+ P PP PP + S + + P G
Sbjct: 304 APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNG 363
Query: 244 SP-------PAPHASSSPPSDPPLFHCSDA----LTPPPLPPSNNLPAHPGPASQPPVSS 292
+P P HA + P PP + S + P +P + L GP
Sbjct: 364 APGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP------- 416
Query: 293 ATMHLPLVLGPLG--GAPTVEGPGAPPFLASSLLSAAAKAQH-----PPLPPPSTLQGRR 345
GP G GAP + G P + + + P +P G+
Sbjct: 417 ---------GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467
Query: 346 PRAQAPSASHSSSLRPSQRRP--RRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE 403
P A+ + P R P + +GP R AP P + E
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG----APGPAGPRGAAGE 523
Query: 404 PSQPILPSVLSLLGLP-TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI-QPSL 461
P + +P + G+P +PG SDG GS P PP P P QP +
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP------GPPGPSGPRGQPGV 577
Query: 462 PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLA--GGEAFP 519
G + GAP P P P G GP P P G P
Sbjct: 578 MGFPGPKGND--GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP 635
Query: 520 FPSPEQGLALSGA--------GFPGMLGALPLPLSLGQP----PPSPLLNHSLFGV--LT 565
P QGL +G G PG G P + G P L G L
Sbjct: 636 GPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR 695
Query: 566 GGGGQPPPE-------PLLPPP-----------------GGPGPPLAPGEPEGPSLLVAS 601
GG G P PE P PP G PGP GEP GP A
Sbjct: 696 GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPG---AD 752
Query: 602 LLP------PPPSDLLPP-PSAPPSNLLASFLPLL--ALGPTAGDGEGSAEGAGGPSGEP 652
+P P + PP P+ P + P L GP GE G GP+G P
Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812
Query: 653 FS--------GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGT----PPQPCVLSA 700
+ G G+ PP PP G+ PP P +
Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPP-----------GVAGPPGGSGPAGPPGPQGVKG 861
Query: 701 PQ--PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGAL 758
+ PG P A PGA L P ++G P P
Sbjct: 862 ERGSPGGP-----GAAGFPGARGLPGPPGSNGNPG------------------PPGPSGS 898
Query: 759 PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESP 818
P PPGP +G G PG P +A P Q PP P + +
Sbjct: 899 PGKDGPPGP--AGNTGAPGSPGVSGPK--GDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954
Query: 819 ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRG-----SGKRGRRGGGGLRGINGEA- 872
A L P P P GSP P + +G+ SG+RG G GL G+ G A
Sbjct: 955 ARGLAGPPGMP------GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008
Query: 873 RPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPP 932
P R PGS PGR G+ GG + E NG GA P P PP
Sbjct: 1009 EPGRDGNPGSDGLPGR----DGSPGGKGDRGE-----------NGSPGAPGA-PGHPGPP 1052
Query: 933 GP 934
GP
Sbjct: 1053 GP 1054
Score = 99.4 bits (246), Expect = 2e-20
Identities = 213/827 (25%), Positives = 270/827 (32%), Gaps = 171/827 (20%)
Query: 126 PGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAG-PGGL 184
PG+ SP SPGPP C PT P N P + S A LAG PG
Sbjct: 126 PGQPGSPG-----SPGPPGICESC---PTGPQNYSPQYDSYDVKS-GVAVGGLAGYPGPA 176
Query: 185 FPPRLADPVPSG-----------GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAAL 233
PP P P G G P P PS P PP AI + P+ G +
Sbjct: 177 GPP--GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESG 234
Query: 234 RSSLVPSDLG--SPPAPHASSSPPSDPPL-----FHCSDA----LTPPPLPPSNNLPAH- 281
R P + G PP + P P + F + P L N LP
Sbjct: 235 RPGR-PGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293
Query: 282 --PGPASQ--PPVSSATMHLPLVLGPLG-----GAPTVEGPGAPPFLASSLLSAAAKAQH 332
PGP P LP G G G+ GP PP A S AK +
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353
Query: 333 PPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAP 392
P P + R + H+ + + P PP + G+G P
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGA-----QGPPGPPGINGSPGGKGEM--------GP 400
Query: 393 APVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQ 452
A +P P ++ G PGP+ ++G+ L G P + G P
Sbjct: 401 AGIPG-----------APGLMGARG--PPGPAGANGAPGLRGGAGE--PGKNGAKGEPGP 445
Query: 453 PRHPIQPSLPGTTSG-SLSSVPGAPAPPAASKAPVVP----SPVLQSPS--EGLGMGAGP 505
+ +PG G+P P A+ P +P + P+ G+ GP
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 506 ACPLPPLAGGEAFPFPSPEQGLALSGA--GFPGMLGALPLPLSLGQPPPSPLLNHSLFGV 563
AG P P+ +G A G PG G +P S G P
Sbjct: 506 -------AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP------------- 545
Query: 564 LTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPP--------PS 615
G G+P P G PGPP P P G ++ P P + P P
Sbjct: 546 --GSDGKPGPPGSQGESGRPGPP-GPSGPRGQPGVMG--FPGPKGNDGAPGKNGERGGPG 600
Query: 616 APPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIA 675
P GP +GE +G GP+G P GD P P L
Sbjct: 601 GPGPQ-----------GPPGKNGETGPQGPPGPTG-PGGDKGDTGP------PGPQGLQG 642
Query: 676 LNSALLAATLDPPSGTPPQPCVLSAPQPGPP-TSSVTTATTDPGASSLGKAPSNSGRPPQ 734
L P +G PP +PG P A PG AP G P
Sbjct: 643 L----------PGTGGPPG----ENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP-- 686
Query: 735 LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGG----GAPPPLSEA 790
L GA L + G + P P +G GLQ +PG G+P P +
Sbjct: 687 ---GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743
Query: 791 SSPLACLLQSLQIPPEQPEAPCLPPESPASALEP----EPARPPLSALAPPHGSP----- 841
P + + P P P P A +P E P L +A P GSP
Sbjct: 744 GEPGGPGADGVP-GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802
Query: 842 -DPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPG 887
PP P G G+ G GG G RG GE G PG PG
Sbjct: 803 TGPPGPAGFPG-APGQNGEPGGKGERGAPGE--KGEGGPPGVAGPPG 846
Score = 75.5 bits (184), Expect = 2e-13
Identities = 148/595 (24%), Positives = 189/595 (31%), Gaps = 100/595 (16%)
Query: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSS 199
PG P P T G G P P Q P GP G + +P P G +
Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-NGKPGEPGPKGDAG 666
Query: 200 SPRFLP-RGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDP 258
+P +G+A +P PP ++ AP GA PP P ++ P
Sbjct: 667 APGAPGGKGDAGAPGERGPPGLA-GAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725
Query: 259 PLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG--GAPTVEGPGAP 316
+ L P P PG A P +GP G G P +G G
Sbjct: 726 GMPGERGGLGSPGPKGDKGEPGGPG-ADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784
Query: 317 PFL---ASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373
P L A S + + P P P+ G + P P ++ PP V
Sbjct: 785 PGLPGIAGPRGSPGERGETGP-PGPAGFPGAPGQNGEPGGKGERGA-PGEKGEGGPPGVA 842
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLP-------TPGPSHS 426
G GP P P P P P GLP PGP
Sbjct: 843 GPPGGSGPAGP-------PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGP 895
Query: 427 DGSFNLLGSDAHLPPPPTLSSGSPPQPR---------HPIQPSLPG-------------- 463
GS G D PP P ++G+P P P + PG
Sbjct: 896 SGS---PGKDG--PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIA 950
Query: 464 --TTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP--LPPLAGGEAFP 519
T + L+ PG P P + V + + GL GP P LP LAG P
Sbjct: 951 GITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP 1010
Query: 520 FPSPEQGL--------ALSGAGFPGMLGALPLPLSLGQP-PPSPLLNHSLFGVL-----T 565
G + G G G G+ P + G P PP P+ G
Sbjct: 1011 GRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPA 1070
Query: 566 GGGGQPPPEPLLPPPGGPGP------------------------PLAPGEPEGPSLLVAS 601
G G P P PG GP P APG P GP+ +
Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-GPAGQQGA 1129
Query: 602 LLPPPPSDLLPP--PSAPPSNLLASFLP--LLALGPTAGDGEGSAEGAGGPSGEP 652
+ P P+ P PS PP S P + GP GE +EG+ G G+P
Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184
Score = 65.1 bits (157), Expect = 3e-10
Identities = 150/613 (24%), Positives = 193/613 (31%), Gaps = 105/613 (17%)
Query: 366 PRRPPTVFRLLEGRGPQTPRRSR--PRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGP 423
P RPP G+GPQ P+ P P P +P P P + GP
Sbjct: 95 PTRPPN------GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Query: 424 SHSDGSFNLLGSDAHL----------------PPPPTLSSGSPPQPRHPIQPSLPGTTSG 467
+ ++ + + PP P +SG P P P PG
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208
Query: 468 SLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGL 527
+ S G P PP A + PS P+ G P P G P P +G
Sbjct: 209 AGPS--GPPGPPGA----IGPS----GPAGKDGESGRPGRP-----GERGLPGPPGIKGP 253
Query: 528 ALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPL 587
A GFPGM G G+ + L G G P P + P G PG
Sbjct: 254 A-GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGP---MGPRGAPGERG 309
Query: 588 APGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG 647
PG P SD P P PP G G A+G G
Sbjct: 310 RPGLPGAAG--ARGNDGARGSDGQPGPPGPP-------------GTAGFPGSPGAKGEVG 354
Query: 648 PSGEPFSG-----LGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQ 702
P+G P S G+ P PP +N + P+G P P ++ A
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414
Query: 703 PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLL 762
P P + GA GK + P+ G+ + + PGA
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR--------GERGE-AGIPGVPGAKGEDG 465
Query: 763 QPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASAL 822
+ P G GL G P + P + + P + AP P P A
Sbjct: 466 KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG--IPGEKGPAGERGAP--GPAGPRGA- 520
Query: 823 EPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGS 882
EP R + G P P G G G+ G G +G +G RP G
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSP-------GGPGSDGKPGPPGSQGESG--RPGPPGPSGP 571
Query: 883 RREPGRLAL-----------KWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPP 931
R +PG + K G RGG G + P NGE G P P
Sbjct: 572 RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP-----GKNGETGPQG--PPGPTG 624
Query: 932 PGPHSEDLKVPPG 944
PG D PPG
Sbjct: 625 PGGDKGDTG-PPG 636
Score = 65.1 bits (157), Expect = 3e-10
Identities = 129/504 (25%), Positives = 156/504 (30%), Gaps = 129/504 (25%)
Query: 127 GEGASPQMFHTVSP-GPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLF 185
GEG +P + P G P R P G PG + P G GG
Sbjct: 780 GEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG-- 837
Query: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
PP +A P GGS PA PP P V + GSP
Sbjct: 838 PPGVAGP--PGGSG------------PAGPPGP-----------------QGVKGERGSP 866
Query: 246 PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPV--------SSATMHL 297
P A+ P A P P SN P PGP+ P ++
Sbjct: 867 GGPGAAGFP----------GARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS 916
Query: 298 PLVLGPLG--------GAPTVEGP-GAP-PFLASSLLSAAAKAQHPPLPPPSTLQGRRPR 347
P V GP G G+P +GP GAP P + + A A P +P P G
Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG---- 972
Query: 348 AQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQP 407
P S +P L RGP P+ P +P P
Sbjct: 973 ---PQGVKGESGKPGANG---------LSGERGPPGPQ-GLPGLAGTAGEPGRDGNPGSD 1019
Query: 408 ILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSG 467
LP G S G G + S G+P P HP P G
Sbjct: 1020 GLP-----------GRDGSPGGKGDRGENG--------SPGAPGAPGHPGPPGPVGPAGK 1060
Query: 468 SLSSVPGAPAPPAASKAPV----VPSPVLQSPSEG-------------LGMGAGPACPLP 510
S PA PA + P P P +G G P P
Sbjct: 1061 SGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120
Query: 511 PLAGGE----AFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTG 566
P G+ P P+ +G + +G PG G P +G PP P N G G
Sbjct: 1121 PGPAGQQGAIGSPGPAGPRG-PVGPSGPPGKDGTSGHPGPIG--PPGPRGNRGERG-SEG 1176
Query: 567 GGGQPPPEPLLPPPGGPGPPLAPG 590
G P PG PGPP APG
Sbjct: 1177 SPGHP------GQPGPPGPPGAPG 1194
Score = 60.8 bits (146), Expect = 6e-09
Identities = 143/550 (26%), Positives = 176/550 (32%), Gaps = 116/550 (21%)
Query: 453 PRHPIQPSLPGTTSGSLSSV--PGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLP 510
P+ P P+ P G PG P P + P +P SP G +CP
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQP-GSPGSPGPPGICESCPTG 147
Query: 511 PLAGGEAFPFPSPEQGLALSG-AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGG 569
P + + G+A+ G AG+PG G PP P
Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAG-----------PPGP--------------- 181
Query: 570 QPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLL 629
P P PG PG P G P P S P PP + PS P S P
Sbjct: 182 -PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI--GPSGPAGKDGESGRP-- 236
Query: 630 ALGPTAGDGEGSAEGAGGPSGEP-FSGL----------GDLSPLLFPPLSAPPTLIALNS 678
G G G GP+G P F G+ G+ P L L N
Sbjct: 237 --GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294
Query: 679 ALLAATLDP-----PSGTPPQPCVLSA----------PQPGPPTSSVTTA-TTDPGA-SS 721
A + P G P P A QPGPP T PGA
Sbjct: 295 A--PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE 352
Query: 722 LGKA--PSNSGRPPQLLSP----LLGASLLGDLSSLTSSPG-----------ALPSLL-- 762
+G A P ++G P Q P GA + SPG P L+
Sbjct: 353 VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGA 412
Query: 763 -QPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASA 821
PPGP +G G L GG P + A + + P P E
Sbjct: 413 RGPPGP--AGANGAPGLRGGAGEPGKNGAKGEPG--PRGERGEAGIPGVPGAKGEDGKDG 468
Query: 822 LEPEPARPPLSALAPPHGSP---DPPVPELLTGR--GSGKRGRRGGGGLRGINGEARPAR 876
EP L A G+P P P + G +G+RG G G RG GE P R
Sbjct: 469 SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE--PGR 526
Query: 877 GRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHS 936
PG PG + G+ GG + P G E G P P P GP
Sbjct: 527 DGVPGG---PGMRGMP-GSPGGPGSDGKPGP--------PGSQGESG-RPGPPGPSGPRG 573
Query: 937 EDLKVPPGVV 946
+ PGV+
Sbjct: 574 Q-----PGVM 578
Score = 45.4 bits (106), Expect = 3e-04
Identities = 92/399 (23%), Positives = 118/399 (29%), Gaps = 71/399 (17%)
Query: 141 GPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL-FPPRLADPVPSGGSS 199
GPP P P GP PP P V + GPG FP P P G +
Sbjct: 837 GPPGVAGP-------PGGSGPAG-PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG 888
Query: 200 SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL-VPSDLGSPPA--PHASSSPPS 256
+P +P PP PA + AP + + P + GSP A P + P
Sbjct: 889 NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG 948
Query: 257 DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSAT-----------MHLPLVLGPLG 305
+ PP +P P G + A LP + G G
Sbjct: 949 IAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008
Query: 306 -----------GAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSA 353
G P +G PG + A A P PP + + S
Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG 1068
Query: 354 SHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSR----PRAPAPVPQPFSLP----EPS 405
+ P R P GPQ PR + R A + P P
Sbjct: 1069 PAGPAGAPGPAGSRGAP---------GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG 1119
Query: 406 QPILPSVLSLLGLPTP-------GPSHSDGSFNLLGSDAHLPPPPTL----------SSG 448
P +G P P GPS G G + PP S G
Sbjct: 1120 SPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG 1179
Query: 449 SPPQPRHPIQPSLPGTTSGSL--SSVPGAPAPPAASKAP 485
P QP P P PG G + +++ G A AP
Sbjct: 1180 HPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218
Score = 34.7 bits (78), Expect = 0.46
Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 48/206 (23%)
Query: 806 EQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGL 865
+ E C PE P +PP + PP+G G +G G G+
Sbjct: 68 DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGP-----------QGPKGDPGPPGI 116
Query: 866 RGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG-- 923
G NG+ P +PGS PG + G SP+ + +G +A GG
Sbjct: 117 PGRNGD--PGIPGQPGSPGSPGPPGI---CESCPTGPQNYSPQYDSYDVKSG-VAVGGLA 170
Query: 924 AEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVP 983
P PPGP PPG +P + Q EP + P
Sbjct: 171 GYPGPAGPPGPPG-----PPGT----------SGHPGSPGSPGYQGPPGEPGQAGPSGPP 215
Query: 984 LPPRA--------------RPGRPAK 995
PP A RPGRP +
Sbjct: 216 GPPGAIGPSGPAGKDGESGRPGRPGE 241
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 102 bits (253), Expect = 2e-21
Identities = 123/441 (27%), Positives = 158/441 (35%), Gaps = 83/441 (18%)
Query: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
PP L P+G + +P P G P P P P+ + P GSP
Sbjct: 184 PPALQ--APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----------------GSP 225
Query: 246 PAPHASSSP--PSDP-PLFHCSDA-LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
A A + P P+ P P H A P PPS + P HP P PP+ T
Sbjct: 226 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPS 283
Query: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP-----PPSTLQGRRPRAQAPSAS-- 354
P P + G G P L A QHP P PP QG+ P +P+A+
Sbjct: 284 APSHAQPPLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
Query: 355 HSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
H+S P+ + + Q P R +P PAP+ P P P+ PI
Sbjct: 341 HTSLQLPASQSALQ------------SQQPPREQPLPPAPLAMPHIKPPPTTPIPQ---- 384
Query: 415 LLGLPTP----GPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
LP P P H G + +A+LPPPP L S HP P S
Sbjct: 385 ---LPAPQAHKHPPHLSGP-SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 440
Query: 471 S-VPGAPA-PPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528
+P +PA PP +++ +P P P GL A P PP A P P
Sbjct: 441 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA----PQPPFAQHPFVPGGPP----P 492
Query: 529 LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPP-------------EP 575
++ P P + QPP S G + GG P P EP
Sbjct: 493 ITPPTCPSTSTPPAGPGTSAQPPCSGAAASG--GSIAGGSSCPLPTVQIKEEALDDAEEP 550
Query: 576 LLPPPGGPGPPLAPGEPEGPS 596
PPP P P + PS
Sbjct: 551 ESPPPPPRSPSPEPTVVDTPS 571
Score = 86.7 bits (213), Expect = 1e-16
Identities = 177/755 (23%), Positives = 234/755 (30%), Gaps = 182/755 (24%)
Query: 307 APTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS--ASHSSSLRPSQR 364
+P+ + A ++ +A K + P + + +R + + + A +SS + +
Sbjct: 59 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 118
Query: 365 RPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS 424
RP + EG G + RS + P+ + + ++ PS+ P+P +
Sbjct: 119 EISRPNSPS---EGEGESSDSRSVNDEGSSDPK--DIDQDNRSTSPSI------PSPQDN 167
Query: 425 HSDGSFNLLGSDAHLPPP---------PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGA 475
SD + PP P SS P P+ P P T+ P A
Sbjct: 168 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 227
Query: 476 PAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP 535
P +AP P P P P PP P PSP
Sbjct: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-------PHPSPH----------- 269
Query: 536 GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP-PEPLLPPPGGPGPPLAPGEPEG 594
PP PL TG GQP P PP G GPP G
Sbjct: 270 --------------PPLQPL---------TGSAGQPSAPSHAQPPLHGQGPP-------G 299
Query: 595 PSLLVASLL---PPPPSDLLPPPSAPPSNLLASFLPLLALGPTA---GDGEGSAEGAGGP 648
P L A L P PP PP A P A T+ + + + P
Sbjct: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359
Query: 649 SGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS 708
+P +PL P + PPT A PP + P P ++A P PP
Sbjct: 360 REQPLPP----APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 415
Query: 709 SVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ----P 764
SSL S PP L L+ L SSP P L Q P
Sbjct: 416 K--------PLSSLSTHHPPSAHPPPL-------QLMPQSQPLPSSPAQPPGLTQSQNLP 460
Query: 765 PGPLLSGQLGLQ------------LLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPC 812
P P GL +PGG PPP++ + P S PP P
Sbjct: 461 PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPTCP------STSTPPAGPGTSA 512
Query: 813 LPPESPASAL------------------------EPEPARPPLSALAPPHGSPDPPVPEL 848
PP S A+A EP PP PP SP P +
Sbjct: 513 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-----PPPRSPSPEPTVV 567
Query: 849 LTGRGSGKRGRRGGGGLRGINGEAR------PARGRKPGSRREPGRLALKWGTRGGFNGQ 902
T + + R RG N AR P G K +RE K +
Sbjct: 568 DTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE 627
Query: 903 MERSPRRTHHWQHNGEL---AEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNP 959
ER + + E AE A+ G S+ PG +R S
Sbjct: 628 REREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS---------- 677
Query: 960 TRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
EP PT AAV PP P PA
Sbjct: 678 ------------FEPPPTTIAAV--PPYIGPDTPA 698
Score = 78.6 bits (192), Expect = 3e-14
Identities = 114/418 (27%), Positives = 141/418 (33%), Gaps = 65/418 (15%)
Query: 122 SHSSPGEGASPQMFHTVSPG---PPSARP-PCRVPPTTPLNGGPGSLPPEPPSVSQAFPT 177
+ S A QM P P P P PP TP PG P Q PT
Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 226
Query: 178 LAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL 237
A P PVP L PSP PPP P S + P
Sbjct: 227 -ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--SPHPP---------LQP 274
Query: 238 VPSDLGSPPAPHASSSP--PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATM 295
+ G P AP + P PP H A P P P P PP +S
Sbjct: 275 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA------GPLLQHPGPPQPFGLPPQASQGQ 328
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP---PPSTLQGRRPRAQAPS 352
PLG +P P L +S +A ++Q PP PP+ L P + P
Sbjct: 329 ------APLGTSPAAAYPHTSLQLPAS--QSALQSQQPPREQPLPPAPL--AMPHIKPPP 378
Query: 353 ASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQP--ILP 410
+ L P+ + + PP L G P + + P P P +P S P P
Sbjct: 379 TTPIPQL-PAPQAHKHPPH----LSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHP 431
Query: 411 SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
L L+ P PS S L +LPPPP + PP H + P P
Sbjct: 432 PPLQLMPQSQPLPS-SPAQPPGLTQSQNLPPPP---ASHPPTGLHQVAPQPP---FAQHP 484
Query: 471 SVPGAPAP------PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522
VPG P P P+ S P P Q P G G +AGG + P P+
Sbjct: 485 FVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------SIAGGSSCPLPT 536
Score = 77.4 bits (189), Expect = 6e-14
Identities = 133/505 (26%), Positives = 166/505 (32%), Gaps = 97/505 (19%)
Query: 256 SDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPT-VEGPG 314
+ PP +TP P P P P P SAT P AP + P
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPT 238
Query: 315 APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFR 374
AP + A Q PP P P P Q + S PS +P
Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP------- 291
Query: 375 LLEGRGPQTPRRSRP----RAPAPVPQPFSL-PEPSQPILPSVLSLLGLPTPGPSHSDGS 429
L G+GP P + + P P PQPF L P+ SQ P LG +P ++ S
Sbjct: 292 -LHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQASQGQAP-----LG-TSPAAAYPHTS 343
Query: 430 FNLLGSDAHLPPPPTLSSGSPP--QPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487
L S + L S PP QP P ++P + +P PAP A P +
Sbjct: 344 LQLPASQS------ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397
Query: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSL 547
P SP + P L PL+ PS M + PLP S
Sbjct: 398 SGP---SPF-SMNANLPPPPALKPLSSLSTHHPPSAHP------PPLQLMPQSQPLPSSP 447
Query: 548 GQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPG----GPGPPLA--PGEPEGPSLLVAS 601
QPP LT PPP PP G P PP A P P GP
Sbjct: 448 AQPPG-----------LTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP------ 490
Query: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661
PP P S PP+ S P P +G AGG S P
Sbjct: 491 --PPITPPTCPSTSTPPAGPGTSAQP-----PCSGAAASGGSIAGGSS----------CP 533
Query: 662 LLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA-- 719
L PT+ AL A + P PP P +P P P + +
Sbjct: 534 L--------PTVQIKEEALDDA--EEPESPPPPP---RSPSPEPTVVDTPSHASQSARFY 580
Query: 720 SSLGKAPSNSGRPPQLLSPLLGASL 744
L + ++ R PL G+ L
Sbjct: 581 KHLDRGYNSCARTDLYFMPLAGSKL 605
Score = 64.3 bits (155), Expect = 5e-10
Identities = 105/408 (25%), Positives = 132/408 (32%), Gaps = 95/408 (23%)
Query: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLAD 191
PQ T S P + P P T + P P PPS PP
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP-------------HPPPHPS 267
Query: 192 PVP-----SGGSSSPRFLPRGNAPSPAPPPPPAISLNA--------PSYNWGAALRSSLV 238
P P +G + P P PP SL A P +G ++S
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 327
Query: 239 PSDLGSPPA---PHASSSPPSDPPLFHCSDALTPPPLPPS-----NNLPAHPGPASQPPV 290
+ LG+ PA PH S P+ PLPP+ + P P Q P
Sbjct: 328 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 387
Query: 291 SSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPL--PPPSTLQGR---- 344
A H P + GP +P PP A LS+ + HPP PPP L +
Sbjct: 388 PQAHKHPPHLSGP---SPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQSQPL 443
Query: 345 -RPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE 403
AQ P + S +L P PPT L PQ P P P P
Sbjct: 444 PSSPAQPPGLTQSQNLPPPP--ASHPPTG---LHQVAPQPPFAQHPFVPGGPP------- 491
Query: 404 PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG 463
PI P P GP G+ A P +SG S+ G
Sbjct: 492 ---PITPPTCPSTSTPPAGP----------GTSAQPPCSGAAASGG----------SIAG 528
Query: 464 TTSGSLSSV------------PGAPAPPAASKAP---VVPSPVLQSPS 496
+S L +V P +P PP S +P VV +P S S
Sbjct: 529 GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 576
Score = 31.6 bits (70), Expect = 3.9
Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 28/89 (31%)
Query: 503 AGPACPL--PPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPP-PSPLLNHS 559
AGP PL P AG FP P G LP PL LGQPP +L H
Sbjct: 895 AGPVHPLVDPLTAGPHLARFPYPP--------------GTLPNPL-LGQPPHEHEMLRHP 939
Query: 560 LFGVLTGGGGQPPPEPLLPPPGGPGPPLA 588
+FG P P L PG PP++
Sbjct: 940 VFGT-------PYPRDL---PGAIPPPMS 958
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 102 bits (253), Expect = 2e-21
Identities = 123/441 (27%), Positives = 158/441 (35%), Gaps = 83/441 (18%)
Query: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
PP L P+G + +P P G P P P P+ + P GSP
Sbjct: 738 PPALQ--APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----------------GSP 779
Query: 246 PAPHASSSP--PSDP-PLFHCSDA-LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
A A + P P+ P P H A P PPS + P HP P PP+ T
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPS 837
Query: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP-----PPSTLQGRRPRAQAPSAS-- 354
P P + G G P L A QHP P PP QG+ P +P+A+
Sbjct: 838 APSHAQPPLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 355 HSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
H+S P+ + + Q P R +P PAP+ P P P+ PI
Sbjct: 895 HTSLQLPASQSALQ------------SQQPPREQPLPPAPLAMPHIKPPPTTPIPQ---- 938
Query: 415 LLGLPTP----GPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
LP P P H G + +A+LPPPP L S HP P S
Sbjct: 939 ---LPAPQAHKHPPHLSGP-SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994
Query: 471 S-VPGAPA-PPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528
+P +PA PP +++ +P P P GL A P PP A P P
Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA----PQPPFAQHPFVPGGPP----P 1046
Query: 529 LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPP-------------EP 575
++ P P + QPP S G + GG P P EP
Sbjct: 1047 ITPPTCPSTSTPPAGPGTSAQPPCSGAAASG--GSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 576 LLPPPGGPGPPLAPGEPEGPS 596
PPP P P + PS
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPS 1125
Score = 86.7 bits (213), Expect = 1e-16
Identities = 177/755 (23%), Positives = 234/755 (30%), Gaps = 182/755 (24%)
Query: 307 APTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS--ASHSSSLRPSQR 364
+P+ + A ++ +A K + P + + +R + + + A +SS + +
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 672
Query: 365 RPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS 424
RP + EG G + RS + P+ + + ++ PS+ P+P +
Sbjct: 673 EISRPNSPS---EGEGESSDSRSVNDEGSSDPK--DIDQDNRSTSPSI------PSPQDN 721
Query: 425 HSDGSFNLLGSDAHLPPP---------PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGA 475
SD + PP P SS P P+ P P T+ P A
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 476 PAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP 535
P +AP P P P P PP P PSP
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-------PHPSPH----------- 823
Query: 536 GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP-PEPLLPPPGGPGPPLAPGEPEG 594
PP PL TG GQP P PP G GPP G
Sbjct: 824 --------------PPLQPL---------TGSAGQPSAPSHAQPPLHGQGPP-------G 853
Query: 595 PSLLVASLL---PPPPSDLLPPPSAPPSNLLASFLPLLALGPTA---GDGEGSAEGAGGP 648
P L A L P PP PP A P A T+ + + + P
Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913
Query: 649 SGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS 708
+P +PL P + PPT A PP + P P ++A P PP
Sbjct: 914 REQPLPP----APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 969
Query: 709 SVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ----P 764
SSL S PP L L+ L SSP P L Q P
Sbjct: 970 K--------PLSSLSTHHPPSAHPPPL-------QLMPQSQPLPSSPAQPPGLTQSQNLP 1014
Query: 765 PGPLLSGQLGLQ------------LLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPC 812
P P GL +PGG PPP++ + P S PP P
Sbjct: 1015 PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPTCP------STSTPPAGPGTSA 1066
Query: 813 LPPESPASAL------------------------EPEPARPPLSALAPPHGSPDPPVPEL 848
PP S A+A EP PP PP SP P +
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-----PPPRSPSPEPTVV 1121
Query: 849 LTGRGSGKRGRRGGGGLRGINGEAR------PARGRKPGSRREPGRLALKWGTRGGFNGQ 902
T + + R RG N AR P G K +RE K +
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE 1181
Query: 903 MERSPRRTHHWQHNGEL---AEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNP 959
ER + + E AE A+ G S+ PG +R S
Sbjct: 1182 REREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS---------- 1231
Query: 960 TRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
EP PT AAV PP P PA
Sbjct: 1232 ------------FEPPPTTIAAV--PPYIGPDTPA 1252
Score = 78.6 bits (192), Expect = 3e-14
Identities = 114/418 (27%), Positives = 141/418 (33%), Gaps = 65/418 (15%)
Query: 122 SHSSPGEGASPQMFHTVSPG---PPSARP-PCRVPPTTPLNGGPGSLPPEPPSVSQAFPT 177
+ S A QM P P P P PP TP PG P Q PT
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 178 LAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL 237
A P PVP L PSP PPP P S + P
Sbjct: 781 -ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--SPHPP---------LQP 828
Query: 238 VPSDLGSPPAPHASSSP--PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATM 295
+ G P AP + P PP H A P P P P PP +S
Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA------GPLLQHPGPPQPFGLPPQASQGQ 882
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP---PPSTLQGRRPRAQAPS 352
PLG +P P L +S +A ++Q PP PP+ L P + P
Sbjct: 883 ------APLGTSPAAAYPHTSLQLPAS--QSALQSQQPPREQPLPPAPL--AMPHIKPPP 932
Query: 353 ASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQP--ILP 410
+ L P+ + + PP L G P + + P P P +P S P P
Sbjct: 933 TTPIPQL-PAPQAHKHPPH----LSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHP 985
Query: 411 SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
L L+ P PS S L +LPPPP + PP H + P P
Sbjct: 986 PPLQLMPQSQPLPS-SPAQPPGLTQSQNLPPPP---ASHPPTGLHQVAPQPP---FAQHP 1038
Query: 471 SVPGAPAP------PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522
VPG P P P+ S P P Q P G G +AGG + P P+
Sbjct: 1039 FVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------SIAGGSSCPLPT 1090
Score = 77.4 bits (189), Expect = 6e-14
Identities = 133/505 (26%), Positives = 166/505 (32%), Gaps = 97/505 (19%)
Query: 256 SDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPT-VEGPG 314
+ PP +TP P P P P P SAT P AP + P
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 315 APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFR 374
AP + A Q PP P P P Q + S PS +P
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP------- 845
Query: 375 LLEGRGPQTPRRSRP----RAPAPVPQPFSL-PEPSQPILPSVLSLLGLPTPGPSHSDGS 429
L G+GP P + + P P PQPF L P+ SQ P LG +P ++ S
Sbjct: 846 -LHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQASQGQAP-----LG-TSPAAAYPHTS 897
Query: 430 FNLLGSDAHLPPPPTLSSGSPP--QPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487
L S + L S PP QP P ++P + +P PAP A P +
Sbjct: 898 LQLPASQS------ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 951
Query: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSL 547
P SP + P L PL+ PS M + PLP S
Sbjct: 952 SGP---SPF-SMNANLPPPPALKPLSSLSTHHPPSAHP------PPLQLMPQSQPLPSSP 1001
Query: 548 GQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPG----GPGPPLA--PGEPEGPSLLVAS 601
QPP LT PPP PP G P PP A P P GP
Sbjct: 1002 AQPPG-----------LTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP------ 1044
Query: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661
PP P S PP+ S P P +G AGG S P
Sbjct: 1045 --PPITPPTCPSTSTPPAGPGTSAQP-----PCSGAAASGGSIAGGSS----------CP 1087
Query: 662 LLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA-- 719
L PT+ AL A + P PP P +P P P + +
Sbjct: 1088 L--------PTVQIKEEALDDA--EEPESPPPPP---RSPSPEPTVVDTPSHASQSARFY 1134
Query: 720 SSLGKAPSNSGRPPQLLSPLLGASL 744
L + ++ R PL G+ L
Sbjct: 1135 KHLDRGYNSCARTDLYFMPLAGSKL 1159
Score = 64.3 bits (155), Expect = 5e-10
Identities = 105/408 (25%), Positives = 132/408 (32%), Gaps = 95/408 (23%)
Query: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLAD 191
PQ T S P + P P T + P P PPS PP
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP-------------HPPPHPS 821
Query: 192 PVP-----SGGSSSPRFLPRGNAPSPAPPPPPAISLNA--------PSYNWGAALRSSLV 238
P P +G + P P PP SL A P +G ++S
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 239 PSDLGSPPA---PHASSSPPSDPPLFHCSDALTPPPLPPS-----NNLPAHPGPASQPPV 290
+ LG+ PA PH S P+ PLPP+ + P P Q P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941
Query: 291 SSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPL--PPPSTLQGR---- 344
A H P + GP +P PP A LS+ + HPP PPP L +
Sbjct: 942 PQAHKHPPHLSGP---SPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQSQPL 997
Query: 345 -RPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE 403
AQ P + S +L P PPT L PQ P P P P
Sbjct: 998 PSSPAQPPGLTQSQNLPPPP--ASHPPTG---LHQVAPQPPFAQHPFVPGGPP------- 1045
Query: 404 PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG 463
PI P P GP G+ A P +SG S+ G
Sbjct: 1046 ---PITPPTCPSTSTPPAGP----------GTSAQPPCSGAAASGG----------SIAG 1082
Query: 464 TTSGSLSSV------------PGAPAPPAASKAP---VVPSPVLQSPS 496
+S L +V P +P PP S +P VV +P S S
Sbjct: 1083 GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130
Score = 31.6 bits (70), Expect = 3.9
Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 28/89 (31%)
Query: 503 AGPACPL--PPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPP-PSPLLNHS 559
AGP PL P AG FP P G LP PL LGQPP +L H
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPP--------------GTLPNPL-LGQPPHEHEMLRHP 1493
Query: 560 LFGVLTGGGGQPPPEPLLPPPGGPGPPLA 588
+FG P P L PG PP++
Sbjct: 1494 VFGT-------PYPRDL---PGAIPPPMS 1512
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 102 bits (253), Expect = 2e-21
Identities = 123/441 (27%), Positives = 158/441 (35%), Gaps = 83/441 (18%)
Query: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
PP L P+G + +P P G P P P P+ + P GSP
Sbjct: 738 PPALQ--APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----------------GSP 779
Query: 246 PAPHASSSP--PSDP-PLFHCSDA-LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
A A + P P+ P P H A P PPS + P HP P PP+ T
Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP--HPPLQPLTGSAGQPS 837
Query: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP-----PPSTLQGRRPRAQAPSAS-- 354
P P + G G P L A QHP P PP QG+ P +P+A+
Sbjct: 838 APSHAQPPLHGQGPP---GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 355 HSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
H+S P+ + + Q P R +P PAP+ P P P+ PI
Sbjct: 895 HTSLQLPASQSALQ------------SQQPPREQPLPPAPLAMPHIKPPPTTPIPQ---- 938
Query: 415 LLGLPTP----GPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
LP P P H G + +A+LPPPP L S HP P S
Sbjct: 939 ---LPAPQAHKHPPHLSGP-SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994
Query: 471 S-VPGAPA-PPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528
+P +PA PP +++ +P P P GL A P PP A P P
Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA----PQPPFAQHPFVPGGPP----P 1046
Query: 529 LSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPP-------------EP 575
++ P P + QPP S G + GG P P EP
Sbjct: 1047 ITPPTCPSTSTPPAGPGTSAQPPCSGAAASG--GSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 576 LLPPPGGPGPPLAPGEPEGPS 596
PPP P P + PS
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPS 1125
Score = 86.7 bits (213), Expect = 1e-16
Identities = 177/755 (23%), Positives = 234/755 (30%), Gaps = 182/755 (24%)
Query: 307 APTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS--ASHSSSLRPSQR 364
+P+ + A ++ +A K + P + + +R + + + A +SS + +
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 672
Query: 365 RPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS 424
RP + EG G + RS + P+ + + ++ PS+ P+P +
Sbjct: 673 EISRPNSPS---EGEGESSDSRSVNDEGSSDPK--DIDQDNRSTSPSI------PSPQDN 721
Query: 425 HSDGSFNLLGSDAHLPPP---------PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGA 475
SD + PP P SS P P+ P P T+ P A
Sbjct: 722 ESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 476 PAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP 535
P +AP P P P P PP P PSP
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP-------PHPSPH----------- 823
Query: 536 GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP-PEPLLPPPGGPGPPLAPGEPEG 594
PP PL TG GQP P PP G GPP G
Sbjct: 824 --------------PPLQPL---------TGSAGQPSAPSHAQPPLHGQGPP-------G 853
Query: 595 PSLLVASLL---PPPPSDLLPPPSAPPSNLLASFLPLLALGPTA---GDGEGSAEGAGGP 648
P L A L P PP PP A P A T+ + + + P
Sbjct: 854 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913
Query: 649 SGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS 708
+P +PL P + PPT A PP + P P ++A P PP
Sbjct: 914 REQPLPP----APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 969
Query: 709 SVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQ----P 764
SSL S PP L L+ L SSP P L Q P
Sbjct: 970 K--------PLSSLSTHHPPSAHPPPL-------QLMPQSQPLPSSPAQPPGLTQSQNLP 1014
Query: 765 PGPLLSGQLGLQ------------LLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPC 812
P P GL +PGG PPP++ + P S PP P
Sbjct: 1015 PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPTCP------STSTPPAGPGTSA 1066
Query: 813 LPPESPASAL------------------------EPEPARPPLSALAPPHGSPDPPVPEL 848
PP S A+A EP PP PP SP P +
Sbjct: 1067 QPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-----PPPRSPSPEPTVV 1121
Query: 849 LTGRGSGKRGRRGGGGLRGINGEAR------PARGRKPGSRREPGRLALKWGTRGGFNGQ 902
T + + R RG N AR P G K +RE K +
Sbjct: 1122 DTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREE 1181
Query: 903 MERSPRRTHHWQHNGEL---AEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNP 959
ER + + E AE A+ G S+ PG +R S
Sbjct: 1182 REREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPS---------- 1231
Query: 960 TRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
EP PT AAV PP P PA
Sbjct: 1232 ------------FEPPPTTIAAV--PPYIGPDTPA 1252
Score = 78.6 bits (192), Expect = 3e-14
Identities = 114/418 (27%), Positives = 141/418 (33%), Gaps = 65/418 (15%)
Query: 122 SHSSPGEGASPQMFHTVSPG---PPSARP-PCRVPPTTPLNGGPGSLPPEPPSVSQAFPT 177
+ S A QM P P P P PP TP PG P Q PT
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 178 LAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL 237
A P PVP L PSP PPP P S + P
Sbjct: 781 -ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--SPHPP---------LQP 828
Query: 238 VPSDLGSPPAPHASSSP--PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATM 295
+ G P AP + P PP H A P P P P PP +S
Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA------GPLLQHPGPPQPFGLPPQASQGQ 882
Query: 296 HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP---PPSTLQGRRPRAQAPS 352
PLG +P P L +S +A ++Q PP PP+ L P + P
Sbjct: 883 ------APLGTSPAAAYPHTSLQLPAS--QSALQSQQPPREQPLPPAPL--AMPHIKPPP 932
Query: 353 ASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQP--ILP 410
+ L P+ + + PP L G P + + P P P +P S P P
Sbjct: 933 TTPIPQL-PAPQAHKHPPH----LSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHP 985
Query: 411 SVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
L L+ P PS S L +LPPPP + PP H + P P
Sbjct: 986 PPLQLMPQSQPLPS-SPAQPPGLTQSQNLPPPP---ASHPPTGLHQVAPQPP---FAQHP 1038
Query: 471 SVPGAPAP------PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522
VPG P P P+ S P P Q P G G +AGG + P P+
Sbjct: 1039 FVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGG------SIAGGSSCPLPT 1090
Score = 77.4 bits (189), Expect = 6e-14
Identities = 133/505 (26%), Positives = 166/505 (32%), Gaps = 97/505 (19%)
Query: 256 SDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPT-VEGPG 314
+ PP +TP P P P P P SAT P AP + P
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 315 APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFR 374
AP + A Q PP P P P Q + S PS +P
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP------- 845
Query: 375 LLEGRGPQTPRRSRP----RAPAPVPQPFSL-PEPSQPILPSVLSLLGLPTPGPSHSDGS 429
L G+GP P + + P P PQPF L P+ SQ P LG +P ++ S
Sbjct: 846 -LHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQASQGQAP-----LG-TSPAAAYPHTS 897
Query: 430 FNLLGSDAHLPPPPTLSSGSPP--QPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487
L S + L S PP QP P ++P + +P PAP A P +
Sbjct: 898 LQLPASQS------ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 951
Query: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSL 547
P SP + P L PL+ PS M + PLP S
Sbjct: 952 SGP---SPF-SMNANLPPPPALKPLSSLSTHHPPSAHP------PPLQLMPQSQPLPSSP 1001
Query: 548 GQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPG----GPGPPLA--PGEPEGPSLLVAS 601
QPP LT PPP PP G P PP A P P GP
Sbjct: 1002 AQPPG-----------LTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP------ 1044
Query: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661
PP P S PP+ S P P +G AGG S P
Sbjct: 1045 --PPITPPTCPSTSTPPAGPGTSAQP-----PCSGAAASGGSIAGGSS----------CP 1087
Query: 662 LLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA-- 719
L PT+ AL A + P PP P +P P P + +
Sbjct: 1088 L--------PTVQIKEEALDDA--EEPESPPPPP---RSPSPEPTVVDTPSHASQSARFY 1134
Query: 720 SSLGKAPSNSGRPPQLLSPLLGASL 744
L + ++ R PL G+ L
Sbjct: 1135 KHLDRGYNSCARTDLYFMPLAGSKL 1159
Score = 64.3 bits (155), Expect = 5e-10
Identities = 105/408 (25%), Positives = 132/408 (32%), Gaps = 95/408 (23%)
Query: 132 PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLAD 191
PQ T S P + P P T + P P PPS PP
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP-------------HPPPHPS 821
Query: 192 PVP-----SGGSSSPRFLPRGNAPSPAPPPPPAISLNA--------PSYNWGAALRSSLV 238
P P +G + P P PP SL A P +G ++S
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 239 PSDLGSPPA---PHASSSPPSDPPLFHCSDALTPPPLPPS-----NNLPAHPGPASQPPV 290
+ LG+ PA PH S P+ PLPP+ + P P Q P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941
Query: 291 SSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPL--PPPSTLQGR---- 344
A H P + GP +P PP A LS+ + HPP PPP L +
Sbjct: 942 PQAHKHPPHLSGP---SPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQSQPL 997
Query: 345 -RPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPE 403
AQ P + S +L P PPT L PQ P P P P
Sbjct: 998 PSSPAQPPGLTQSQNLPPPP--ASHPPTG---LHQVAPQPPFAQHPFVPGGPP------- 1045
Query: 404 PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG 463
PI P P GP G+ A P +SG S+ G
Sbjct: 1046 ---PITPPTCPSTSTPPAGP----------GTSAQPPCSGAAASGG----------SIAG 1082
Query: 464 TTSGSLSSV------------PGAPAPPAASKAP---VVPSPVLQSPS 496
+S L +V P +P PP S +P VV +P S S
Sbjct: 1083 GSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130
Score = 31.6 bits (70), Expect = 3.9
Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 28/89 (31%)
Query: 503 AGPACPL--PPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPP-PSPLLNHS 559
AGP PL P AG FP P G LP PL LGQPP +L H
Sbjct: 1449 AGPVHPLVDPLTAGPHLARFPYPP--------------GTLPNPL-LGQPPHEHEMLRHP 1493
Query: 560 LFGVLTGGGGQPPPEPLLPPPGGPGPPLA 588
+FG P P L PG PP++
Sbjct: 1494 VFGT-------PYPRDL---PGAIPPPMS 1512
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 100 bits (250), Expect = 5e-21
Identities = 238/967 (24%), Positives = 314/967 (32%), Gaps = 185/967 (19%)
Query: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
+ P PP P P ++ PG P P PPS T P PP L +P P
Sbjct: 139 IPPPPPGPAPG----PPQDISEPPGGSPLPSPPS------TAPPP----PPLLLEPPP-- 182
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256
PS APPPPP + +P + + S P D PPAP + P
Sbjct: 183 ------------PPSMAPPPPPVLEALSPPHTLSSP--SIPTPPDF-IPPAPPLAFLAPP 227
Query: 257 DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAP 316
PP+ P P PP+ P G PP + L T P
Sbjct: 228 PPPV--------PAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS 279
Query: 317 PFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLL 376
P A SA P L P + + P P + S ++ +Q PR+ +
Sbjct: 280 P--AEPKGSALGPNPEPHLTFPRSFKVPPP---TPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 377 EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
R P P S PA P PEP P L P S +
Sbjct: 335 PSRLPLPP--SFHIRPASQVYPDRAPEPDCP------GELKATAPASPRLGQSQSQADER 386
Query: 437 AHLPPP-PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
A PPP P L +PP P P P LP P AP P A KA P+ ++P
Sbjct: 387 AGTPPPAPPLPPPAPPLP--PPAPPLP----------PAAPPLPCAQKAAHPPAGFTKTP 434
Query: 496 -SEGLGMGAGPACPLPP-LAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
S + P P P A + P Q L + G+ L P
Sbjct: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
Query: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP----PPSD 609
+ S G G P E LL P PP P + G S L + P P D
Sbjct: 495 TVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Query: 610 LLPPPSAPPS-----NLLASFL---------PLLALGPTAGDGEGSAEGAGGPSGEPFS- 654
+P S PS N L + L P + P EG G + S
Sbjct: 553 YIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSK 612
Query: 655 ----GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP----GPP 706
L S L P S P A+ + P PP+ + A P GP
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPK--AMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPA 670
Query: 707 T------------------SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748
T + +TATT P +S A +SG Q P
Sbjct: 671 TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 749 SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL-------SEASSPLACLLQSL 801
+ SP + L G S + PGGG P L S S +A ++ +L
Sbjct: 731 ARGEGSPSE-ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 802 Q--------IPPEQPEAPCLPPESPASAL-EPEPARPPLSALAPPHGSPDPPVPELLTGR 852
P E E P LP + PASA E R P++ GS P+ LL R
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 853 GSGKRGRRGG---------GGLRGINGEARPARGRKPGSRREPGRLAL------------ 891
++GR G G LR + +A + S+ P +
Sbjct: 847 QRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDS 906
Query: 892 --------KWGTRGGFNGQMERSPRRTHHW---QHNGELAEGGAEPKDPPPPGPHSEDLK 940
KWG R G + + RR H+W + +A P + P P +
Sbjct: 907 PLTTEIPNKWGPRLGRDAEGTELSRR-HNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS 965
Query: 941 VPPGVVRKSRRGRRRKYN------PTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
PP K R ++N P SN +P P A A L ++ P R
Sbjct: 966 SPPSPSNK-REEEEEEFNFEVIPPPPEFSN--------DPEPPAPALQYLGRQSSPPRNN 1016
Query: 995 KNKRRKL 1001
+ R+L
Sbjct: 1017 YSDLRQL 1023
Score = 90.1 bits (222), Expect = 9e-18
Identities = 179/688 (26%), Positives = 232/688 (33%), Gaps = 158/688 (22%)
Query: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF----------HCSDALTP 269
+ LNA N G A+ + VP D SS + L+ + D L P
Sbjct: 82 LPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIP 140
Query: 270 PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAK 329
PP PGPA PP + P GG+P P P LL
Sbjct: 141 PP---------PPGPAPGPPQD--------ISEPPGGSPLPSPPSTAPPPPPLLLE---- 179
Query: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSL----RPSQRRPRRPPTVFRLLEGRGPQTPR 385
P PPPS P +A S H+ S P P PP F
Sbjct: 180 ----PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL----------- 224
Query: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSH--SDGSFNLLGSDAHLPPPP 443
AP P P P P P P + P G + SD + N ++A PP
Sbjct: 225 -------APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
Query: 444 TLSSGSPPQPR-HPIQPSL-PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGM 501
SP +P+ + P+ P T VP P P S PV + EG
Sbjct: 278 R----SPAEPKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 502 GAGPACPLPPL----AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
A PLPP + +P +PE PG L A P SP L
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDC-------PGELKATA--------PASPRLG 377
Query: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG-EPEGPSLLVASLLPPPPSD------- 609
S G PP P LPPP P PP AP P P L A PP+
Sbjct: 378 QSQSQADERAGTPPPAPP-LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 610 ----LLPPPSAPPSNLLASFLPLLALGPTAGD---GEGSAEGAG------------GPSG 650
L P P+ P AS P+ P+ + E +A G GP+
Sbjct: 437 SSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 651 EPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSV 710
P S G P L TL++L P TPP P+ SS+
Sbjct: 497 APQSKEGKKG----PRLPEKETLLSL----------PAKDTPP-----GVPEKSLGGSSL 537
Query: 711 TTATTDPGAS--SLGKAPSNSGRPP-QLLSPLLGASLLGDLSSLTSSPGALPSL-LQPPG 766
T P + S+ P +S P + + L A L S + A PS+ PP
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL-----SSAAEKEAKPSIGSLPPK 592
Query: 767 PLLSGQLGLQLLPGGGAPPPLSEASS-----PLACLLQSLQIPPEQPEAPCLPPESPASA 821
P L G ++ G LS+ + LL + + P+ P +PP++
Sbjct: 593 PRLEGG---RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA---- 645
Query: 822 LEPEPARPPLSAL---APPHGSPDPPVP 846
PEPA PP + L PP + P P
Sbjct: 646 -TPEPAIPPKATLWPATPPKATLGPATP 672
Score = 75.5 bits (184), Expect = 2e-13
Identities = 224/944 (23%), Positives = 301/944 (31%), Gaps = 172/944 (18%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPG----EGASPQ 133
P +P P G+ +GP E +T R V T R+ + EGA+ +
Sbjct: 277 PRSPAEPKGSALGPNPEPHLT---FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 134 MFHTVSPGPPS--ARPPCRV-PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA 190
+ P PPS RP +V P P PG L P+ PRL
Sbjct: 334 APSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA---------------SPRL- 376
Query: 191 DPVPSGGSSSPRFLPRGNAPSPAPP-PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPH 249
G S + R P PAPP PPPA L P+ A PPA
Sbjct: 377 ------GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Query: 250 ASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPAS-QPPVSSATMHLPLVL------- 301
+ S P AL P P PPS A P + P + L
Sbjct: 431 TKTPKSSSP-------ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 302 ---------GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352
GP + EG P L + PP P +L G
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG--------- 534
Query: 353 ASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPS 411
SSL ++ P P+V + + + R+ R A + + PS
Sbjct: 535 ----SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSS-----AAEKEAKPS 585
Query: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSS 471
+ SL P P G G+D P ++ PPQ +L TTS +
Sbjct: 586 IGSL----PPKPRLEGGRICENGADDDKLSKP-VAKNLPPQ-----STTLLPTTSLQPKA 635
Query: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531
+ G PP A+ P +P P+ GPA PL +G + +A +
Sbjct: 636 MLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 532 AGFPGMLGALPLPLSLGQ--PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPG----- 584
P L G P P G G P LP G
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL---LASFLPLLALGPTAGDGEGS 641
P +PG E P L P S+L +A +P LA G AG GE
Sbjct: 756 PKTSPGGGEVPCLY--------------KPHCHQSSLSREVAVVMPTLARGGAAGPGE-- 799
Query: 642 AEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
P G P PP SA PT L + ++ S P +L+A
Sbjct: 800 PVEVKEPPGLPAK----------PPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
Q SV A G SSL + + + S + S G +S T P LP
Sbjct: 847 QRAQKGRSVGAAL---GRSSLPGSLRDHSHQAEASSDSIFHS-QGTPNSFTVVP-KLPKE 901
Query: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEAS--------SPLACLLQSLQIPPEQPEAPCL 813
+ PL + ++ + P G +E S P A + P P+ L
Sbjct: 902 AEKDSPLTT-EIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 814 P-----PESPASALEPEPARPPLSALAPP---HGSPDPPVPELLTGRGSGKRGRRGGGGL 865
P P SP++ E E + PP P+PP P L R L
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 866 RGINGE---ARPARG--RKPGSRREPGRLALKWGTRGG--------FNGQMERSPRRTHH 912
R + A PA G R P R G L+ + GG + G+ R P H
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPH- 1079
Query: 913 WQHNGELAEGGAEPK--DPPPPGPHSEDL----KVPPGVVRKSR 950
G + P P P GP + + PPG + R
Sbjct: 1080 ----GGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR 1119
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 100 bits (250), Expect = 5e-21
Identities = 238/967 (24%), Positives = 314/967 (32%), Gaps = 185/967 (19%)
Query: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
+ P PP P P ++ PG P P PPS T P PP L +P P
Sbjct: 139 IPPPPPGPAPG----PPQDISEPPGGSPLPSPPS------TAPPP----PPLLLEPPP-- 182
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256
PS APPPPP + +P + + S P D PPAP + P
Sbjct: 183 ------------PPSMAPPPPPVLEALSPPHTLSSP--SIPTPPDF-IPPAPPLAFLAPP 227
Query: 257 DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAP 316
PP+ P P PP+ P G PP + L T P
Sbjct: 228 PPPV--------PAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS 279
Query: 317 PFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLL 376
P A SA P L P + + P P + S ++ +Q PR+ +
Sbjct: 280 P--AEPKGSALGPNPEPHLTFPRSFKVPPP---TPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 377 EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
R P P S PA P PEP P L P S +
Sbjct: 335 PSRLPLPP--SFHIRPASQVYPDRAPEPDCP------GELKATAPASPRLGQSQSQADER 386
Query: 437 AHLPPP-PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
A PPP P L +PP P P P LP P AP P A KA P+ ++P
Sbjct: 387 AGTPPPAPPLPPPAPPLP--PPAPPLP----------PAAPPLPCAQKAAHPPAGFTKTP 434
Query: 496 -SEGLGMGAGPACPLPP-LAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
S + P P P A + P Q L + G+ L P
Sbjct: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
Query: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP----PPSD 609
+ S G G P E LL P PP P + G S L + P P D
Sbjct: 495 TVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Query: 610 LLPPPSAPPS-----NLLASFL---------PLLALGPTAGDGEGSAEGAGGPSGEPFS- 654
+P S PS N L + L P + P EG G + S
Sbjct: 553 YIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSK 612
Query: 655 ----GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP----GPP 706
L S L P S P A+ + P PP+ + A P GP
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPK--AMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPA 670
Query: 707 T------------------SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748
T + +TATT P +S A +SG Q P
Sbjct: 671 TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 749 SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL-------SEASSPLACLLQSL 801
+ SP + L G S + PGGG P L S S +A ++ +L
Sbjct: 731 ARGEGSPSE-ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 802 Q--------IPPEQPEAPCLPPESPASAL-EPEPARPPLSALAPPHGSPDPPVPELLTGR 852
P E E P LP + PASA E R P++ GS P+ LL R
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 853 GSGKRGRRGG---------GGLRGINGEARPARGRKPGSRREPGRLAL------------ 891
++GR G G LR + +A + S+ P +
Sbjct: 847 QRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDS 906
Query: 892 --------KWGTRGGFNGQMERSPRRTHHW---QHNGELAEGGAEPKDPPPPGPHSEDLK 940
KWG R G + + RR H+W + +A P + P P +
Sbjct: 907 PLTTEIPNKWGPRLGRDAEGTELSRR-HNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS 965
Query: 941 VPPGVVRKSRRGRRRKYN------PTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
PP K R ++N P SN +P P A A L ++ P R
Sbjct: 966 SPPSPSNK-REEEEEEFNFEVIPPPPEFSN--------DPEPPAPALQYLGRQSSPPRNN 1016
Query: 995 KNKRRKL 1001
+ R+L
Sbjct: 1017 YSDLRQL 1023
Score = 90.1 bits (222), Expect = 9e-18
Identities = 179/688 (26%), Positives = 232/688 (33%), Gaps = 158/688 (22%)
Query: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF----------HCSDALTP 269
+ LNA N G A+ + VP D SS + L+ + D L P
Sbjct: 82 LPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIP 140
Query: 270 PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAK 329
PP PGPA PP + P GG+P P P LL
Sbjct: 141 PP---------PPGPAPGPPQD--------ISEPPGGSPLPSPPSTAPPPPPLLLE---- 179
Query: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSL----RPSQRRPRRPPTVFRLLEGRGPQTPR 385
P PPPS P +A S H+ S P P PP F
Sbjct: 180 ----PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL----------- 224
Query: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSH--SDGSFNLLGSDAHLPPPP 443
AP P P P P P P + P G + SD + N ++A PP
Sbjct: 225 -------APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
Query: 444 TLSSGSPPQPR-HPIQPSL-PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGM 501
SP +P+ + P+ P T VP P P S PV + EG
Sbjct: 278 R----SPAEPKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 502 GAGPACPLPPL----AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
A PLPP + +P +PE PG L A P SP L
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDC-------PGELKATA--------PASPRLG 377
Query: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG-EPEGPSLLVASLLPPPPSD------- 609
S G PP P LPPP P PP AP P P L A PP+
Sbjct: 378 QSQSQADERAGTPPPAPP-LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 610 ----LLPPPSAPPSNLLASFLPLLALGPTAGD---GEGSAEGAG------------GPSG 650
L P P+ P AS P+ P+ + E +A G GP+
Sbjct: 437 SSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 651 EPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSV 710
P S G P L TL++L P TPP P+ SS+
Sbjct: 497 APQSKEGKKG----PRLPEKETLLSL----------PAKDTPP-----GVPEKSLGGSSL 537
Query: 711 TTATTDPGAS--SLGKAPSNSGRPP-QLLSPLLGASLLGDLSSLTSSPGALPSL-LQPPG 766
T P + S+ P +S P + + L A L S + A PS+ PP
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL-----SSAAEKEAKPSIGSLPPK 592
Query: 767 PLLSGQLGLQLLPGGGAPPPLSEASS-----PLACLLQSLQIPPEQPEAPCLPPESPASA 821
P L G ++ G LS+ + LL + + P+ P +PP++
Sbjct: 593 PRLEGG---RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA---- 645
Query: 822 LEPEPARPPLSAL---APPHGSPDPPVP 846
PEPA PP + L PP + P P
Sbjct: 646 -TPEPAIPPKATLWPATPPKATLGPATP 672
Score = 75.5 bits (184), Expect = 2e-13
Identities = 224/944 (23%), Positives = 301/944 (31%), Gaps = 172/944 (18%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPG----EGASPQ 133
P +P P G+ +GP E +T R V T R+ + EGA+ +
Sbjct: 277 PRSPAEPKGSALGPNPEPHLT---FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 134 MFHTVSPGPPS--ARPPCRV-PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA 190
+ P PPS RP +V P P PG L P+ PRL
Sbjct: 334 APSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA---------------SPRL- 376
Query: 191 DPVPSGGSSSPRFLPRGNAPSPAPP-PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPH 249
G S + R P PAPP PPPA L P+ A PPA
Sbjct: 377 ------GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Query: 250 ASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPAS-QPPVSSATMHLPLVL------- 301
+ S P AL P P PPS A P + P + L
Sbjct: 431 TKTPKSSSP-------ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 302 ---------GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352
GP + EG P L + PP P +L G
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG--------- 534
Query: 353 ASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPS 411
SSL ++ P P+V + + + R+ R A + + PS
Sbjct: 535 ----SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSS-----AAEKEAKPS 585
Query: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSS 471
+ SL P P G G+D P ++ PPQ +L TTS +
Sbjct: 586 IGSL----PPKPRLEGGRICENGADDDKLSKP-VAKNLPPQ-----STTLLPTTSLQPKA 635
Query: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531
+ G PP A+ P +P P+ GPA PL +G + +A +
Sbjct: 636 MLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 532 AGFPGMLGALPLPLSLGQ--PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPG----- 584
P L G P P G G P LP G
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL---LASFLPLLALGPTAGDGEGS 641
P +PG E P L P S+L +A +P LA G AG GE
Sbjct: 756 PKTSPGGGEVPCLY--------------KPHCHQSSLSREVAVVMPTLARGGAAGPGE-- 799
Query: 642 AEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
P G P PP SA PT L + ++ S P +L+A
Sbjct: 800 PVEVKEPPGLPAK----------PPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
Q SV A G SSL + + + S + S G +S T P LP
Sbjct: 847 QRAQKGRSVGAAL---GRSSLPGSLRDHSHQAEASSDSIFHS-QGTPNSFTVVP-KLPKE 901
Query: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEAS--------SPLACLLQSLQIPPEQPEAPCL 813
+ PL + ++ + P G +E S P A + P P+ L
Sbjct: 902 AEKDSPLTT-EIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 814 P-----PESPASALEPEPARPPLSALAPP---HGSPDPPVPELLTGRGSGKRGRRGGGGL 865
P P SP++ E E + PP P+PP P L R L
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 866 RGINGE---ARPARG--RKPGSRREPGRLALKWGTRGG--------FNGQMERSPRRTHH 912
R + A PA G R P R G L+ + GG + G+ R P H
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPH- 1079
Query: 913 WQHNGELAEGGAEPK--DPPPPGPHSEDL----KVPPGVVRKSR 950
G + P P P GP + + PPG + R
Sbjct: 1080 ----GGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR 1119
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 100 bits (250), Expect = 5e-21
Identities = 238/967 (24%), Positives = 314/967 (32%), Gaps = 185/967 (19%)
Query: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
+ P PP P P ++ PG P P PPS T P PP L +P P
Sbjct: 139 IPPPPPGPAPG----PPQDISEPPGGSPLPSPPS------TAPPP----PPLLLEPPP-- 182
Query: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256
PS APPPPP + +P + + S P D PPAP + P
Sbjct: 183 ------------PPSMAPPPPPVLEALSPPHTLSSP--SIPTPPDF-IPPAPPLAFLAPP 227
Query: 257 DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAP 316
PP+ P P PP+ P G PP + L T P
Sbjct: 228 PPPV--------PAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS 279
Query: 317 PFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLL 376
P A SA P L P + + P P + S ++ +Q PR+ +
Sbjct: 280 P--AEPKGSALGPNPEPHLTFPRSFKVPPP---TPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 377 EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
R P P S PA P PEP P L P S +
Sbjct: 335 PSRLPLPP--SFHIRPASQVYPDRAPEPDCP------GELKATAPASPRLGQSQSQADER 386
Query: 437 AHLPPP-PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
A PPP P L +PP P P P LP P AP P A KA P+ ++P
Sbjct: 387 AGTPPPAPPLPPPAPPLP--PPAPPLP----------PAAPPLPCAQKAAHPPAGFTKTP 434
Query: 496 -SEGLGMGAGPACPLPP-LAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
S + P P P A + P Q L + G+ L P
Sbjct: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
Query: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP----PPSD 609
+ S G G P E LL P PP P + G S L + P P D
Sbjct: 495 TVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVD 552
Query: 610 LLPPPSAPPS-----NLLASFL---------PLLALGPTAGDGEGSAEGAGGPSGEPFS- 654
+P S PS N L + L P + P EG G + S
Sbjct: 553 YIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSK 612
Query: 655 ----GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP----GPP 706
L S L P S P A+ + P PP+ + A P GP
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPK--AMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPA 670
Query: 707 T------------------SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748
T + +TATT P +S A +SG Q P
Sbjct: 671 TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
Query: 749 SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL-------SEASSPLACLLQSL 801
+ SP + L G S + PGGG P L S S +A ++ +L
Sbjct: 731 ARGEGSPSE-ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 802 Q--------IPPEQPEAPCLPPESPASAL-EPEPARPPLSALAPPHGSPDPPVPELLTGR 852
P E E P LP + PASA E R P++ GS P+ LL R
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 853 GSGKRGRRGG---------GGLRGINGEARPARGRKPGSRREPGRLAL------------ 891
++GR G G LR + +A + S+ P +
Sbjct: 847 QRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDS 906
Query: 892 --------KWGTRGGFNGQMERSPRRTHHW---QHNGELAEGGAEPKDPPPPGPHSEDLK 940
KWG R G + + RR H+W + +A P + P P +
Sbjct: 907 PLTTEIPNKWGPRLGRDAEGTELSRR-HNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS 965
Query: 941 VPPGVVRKSRRGRRRKYN------PTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
PP K R ++N P SN +P P A A L ++ P R
Sbjct: 966 SPPSPSNK-REEEEEEFNFEVIPPPPEFSN--------DPEPPAPALQYLGRQSSPPRNN 1016
Query: 995 KNKRRKL 1001
+ R+L
Sbjct: 1017 YSDLRQL 1023
Score = 90.1 bits (222), Expect = 9e-18
Identities = 179/688 (26%), Positives = 232/688 (33%), Gaps = 158/688 (22%)
Query: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF----------HCSDALTP 269
+ LNA N G A+ + VP D SS + L+ + D L P
Sbjct: 82 LPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIP 140
Query: 270 PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAK 329
PP PGPA PP + P GG+P P P LL
Sbjct: 141 PP---------PPGPAPGPPQD--------ISEPPGGSPLPSPPSTAPPPPPLLLE---- 179
Query: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSL----RPSQRRPRRPPTVFRLLEGRGPQTPR 385
P PPPS P +A S H+ S P P PP F
Sbjct: 180 ----PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL----------- 224
Query: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSH--SDGSFNLLGSDAHLPPPP 443
AP P P P P P P + P G + SD + N ++A PP
Sbjct: 225 -------APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
Query: 444 TLSSGSPPQPR-HPIQPSL-PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGM 501
SP +P+ + P+ P T VP P P S PV + EG
Sbjct: 278 R----SPAEPKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 502 GAGPACPLPPL----AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
A PLPP + +P +PE PG L A P SP L
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDC-------PGELKATA--------PASPRLG 377
Query: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG-EPEGPSLLVASLLPPPPSD------- 609
S G PP P LPPP P PP AP P P L A PP+
Sbjct: 378 QSQSQADERAGTPPPAPP-LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 610 ----LLPPPSAPPSNLLASFLPLLALGPTAGD---GEGSAEGAG------------GPSG 650
L P P+ P AS P+ P+ + E +A G GP+
Sbjct: 437 SSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 651 EPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSV 710
P S G P L TL++L P TPP P+ SS+
Sbjct: 497 APQSKEGKKG----PRLPEKETLLSL----------PAKDTPP-----GVPEKSLGGSSL 537
Query: 711 TTATTDPGAS--SLGKAPSNSGRPP-QLLSPLLGASLLGDLSSLTSSPGALPSL-LQPPG 766
T P + S+ P +S P + + L A L S + A PS+ PP
Sbjct: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL-----SSAAEKEAKPSIGSLPPK 592
Query: 767 PLLSGQLGLQLLPGGGAPPPLSEASS-----PLACLLQSLQIPPEQPEAPCLPPESPASA 821
P L G ++ G LS+ + LL + + P+ P +PP++
Sbjct: 593 PRLEGG---RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA---- 645
Query: 822 LEPEPARPPLSAL---APPHGSPDPPVP 846
PEPA PP + L PP + P P
Sbjct: 646 -TPEPAIPPKATLWPATPPKATLGPATP 672
Score = 75.5 bits (184), Expect = 2e-13
Identities = 224/944 (23%), Positives = 301/944 (31%), Gaps = 172/944 (18%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPG----EGASPQ 133
P +P P G+ +GP E +T R V T R+ + EGA+ +
Sbjct: 277 PRSPAEPKGSALGPNPEPHLT---FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 134 MFHTVSPGPPS--ARPPCRV-PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA 190
+ P PPS RP +V P P PG L P+ PRL
Sbjct: 334 APSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA---------------SPRL- 376
Query: 191 DPVPSGGSSSPRFLPRGNAPSPAPP-PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPH 249
G S + R P PAPP PPPA L P+ A PPA
Sbjct: 377 ------GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Query: 250 ASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPAS-QPPVSSATMHLPLVL------- 301
+ S P AL P P PPS A P + P + L
Sbjct: 431 TKTPKSSSP-------ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 302 ---------GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352
GP + EG P L + PP P +L G
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG--------- 534
Query: 353 ASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPS 411
SSL ++ P P+V + + + R+ R A + + PS
Sbjct: 535 ----SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSS-----AAEKEAKPS 585
Query: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSS 471
+ SL P P G G+D P ++ PPQ +L TTS +
Sbjct: 586 IGSL----PPKPRLEGGRICENGADDDKLSKP-VAKNLPPQ-----STTLLPTTSLQPKA 635
Query: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531
+ G PP A+ P +P P+ GPA PL +G + +A +
Sbjct: 636 MLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
Query: 532 AGFPGMLGALPLPLSLGQ--PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPG----- 584
P L G P P G G P LP G
Sbjct: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
Query: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL---LASFLPLLALGPTAGDGEGS 641
P +PG E P L P S+L +A +P LA G AG GE
Sbjct: 756 PKTSPGGGEVPCLY--------------KPHCHQSSLSREVAVVMPTLARGGAAGPGE-- 799
Query: 642 AEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
P G P PP SA PT L + ++ S P +L+A
Sbjct: 800 PVEVKEPPGLPAK----------PPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
Query: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
Q SV A G SSL + + + S + S G +S T P LP
Sbjct: 847 QRAQKGRSVGAAL---GRSSLPGSLRDHSHQAEASSDSIFHS-QGTPNSFTVVP-KLPKE 901
Query: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEAS--------SPLACLLQSLQIPPEQPEAPCL 813
+ PL + ++ + P G +E S P A + P P+ L
Sbjct: 902 AEKDSPLTT-EIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 814 P-----PESPASALEPEPARPPLSALAPP---HGSPDPPVPELLTGRGSGKRGRRGGGGL 865
P P SP++ E E + PP P+PP P L R L
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 866 RGINGE---ARPARG--RKPGSRREPGRLALKWGTRGG--------FNGQMERSPRRTHH 912
R + A PA G R P R G L+ + GG + G+ R P H
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPH- 1079
Query: 913 WQHNGELAEGGAEPK--DPPPPGPHSEDL----KVPPGVVRKSR 950
G + P P P GP + + PPG + R
Sbjct: 1080 ----GGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR 1119
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 100 bits (249), Expect = 7e-21
Identities = 208/774 (26%), Positives = 262/774 (33%), Gaps = 122/774 (15%)
Query: 143 PSARPPCR--VPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSS 200
P PP + P L+ P P P S+ F LAG G L P L G + +
Sbjct: 173 PPFSPPANGLLSPHDVLHLKPSQAPTVPSSLG--FERLAGGGVLGPAGL------GPAQT 224
Query: 201 PRFLPRGNAPSPAPPP---PPAISLNAPSYNWGAALRSSLVP----SDLGSPPAPHASSS 253
P + P P P PPP P +L A S AA S S P P +
Sbjct: 225 PPYRP--GPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERAL 282
Query: 254 PPSDPPLFHC---SDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTV 310
P D + H + A PPP PP++ L + P S L PLGG
Sbjct: 283 PRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYP--SMGHRANLACSPLGGGEPS 340
Query: 311 EGPGAPPFLASSLLSAAA--KAQHPPLPPPSTLQGR----RPRAQAPS---------ASH 355
G G P S +A A +A P G RP Q+P A+
Sbjct: 341 PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
Query: 356 SSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSL 415
+ RP R P + L G A Q +S P QP L
Sbjct: 401 GGATRPPPPRSTATPKC-QSLGGPAAAYATGKASGAGGAGGQAYS---PGQP-----QGL 451
Query: 416 LGLPTPGPSHSDGSF-NLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPG 474
LG G G +L + ++ PP SG PP Q P G L V G
Sbjct: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511
Query: 475 APAPPAASKAPVVPSPVLQSPSEGLGMGAGPAC--------PLPPLAGGEAF------PF 520
P P A+ + +P+ SPS G PA P GGEA P
Sbjct: 512 EPYPGPAAHSQGLPT---ASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPL 568
Query: 521 PSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPP 580
SP G G PG G + P +P S G G+ LL P
Sbjct: 569 QSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGP 628
Query: 581 GGPGPPLAPGE-PEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGE 639
GGP P E E L+ LL P +PP A L A G
Sbjct: 629 GGP-----PAERTEDEEFLIQHLLQAP---------SPPRTSGADGLVGEDGAADASKGL 674
Query: 640 GSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLS 699
G + GAGGP G P+ L P + S T +L+ AA L+ G +
Sbjct: 675 GGSGGAGGPPGTPYE-LAKEDPQRYHLQSVIRTSASLDEGATAA-LELGLGRLKEK--KK 730
Query: 700 APQPG---PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPG 756
P+ G P + + GA LG S PP + + G L L +
Sbjct: 731 GPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLL--LEAGGP 788
Query: 757 ALPSLLQPPGPLLSGQLGLQLLPG--GGAPPPLSEASSPLACLLQ------SLQIPPEQP 808
LP +L PP P QLLP AP P AS LL+ + Q PP P
Sbjct: 789 DLPLVLPPPPP--------QLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840
Query: 809 EAP--------------CLPPESPASALEPEPARPPLSALAPPHGS--PDPPVP 846
P L P +P+ L PE + P A+ G+ P PP P
Sbjct: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAP 894
Score = 86.3 bits (212), Expect = 1e-16
Identities = 197/788 (25%), Positives = 248/788 (31%), Gaps = 179/788 (22%)
Query: 136 HTVSPGPPSAR--PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPV 193
H + P PS R P + P + G+L P PP+ G G+ PP
Sbjct: 857 HGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPA--------PGDTGVGPPNSEGKD 908
Query: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDL---GSPPAPHA 250
P+G SP P+G + AP P S+ P RS + G +
Sbjct: 909 PAGAYRSPS--PQG---TKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
Query: 251 SSSPPSDPPLFHCSDALTPPPLPPSNNL--PAHPGPASQPPVSSATMHLPLVLGPLGGAP 308
+ PP D PPP PP+ + P PG AS G P
Sbjct: 964 KAGPPEDEG--DPKAGAGPPPGPPAYDPYGPYCPGRAS------------------GAGP 1003
Query: 309 TVEG----PGAPPFLASS--------LLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHS 356
G P PP L S+ + S +A PP PPP P AP++
Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPP-------PPPPAPASEPK 1056
Query: 357 SSLRPS---QRRPRR--PPTVFRLLEGRGP--QTPRR--------SRPRAPAPVPQPFSL 401
L +P++ + F LL R P QTP++ A VP L
Sbjct: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
Query: 402 PEPSQPILPS------VLSLLG-----LPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP 450
P L S LS LG P PGP G P P
Sbjct: 1117 NPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPD---------GPRRRGRKPTKAKRDGP 1167
Query: 451 PQPRHP--IQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPAC- 507
P+PR I+P TT+G S A P +K P G G G G
Sbjct: 1168 PRPRGRPRIRPLEVPTTAGPAS----ASTPTDGAKKP-----------RGRGRGRGRKAE 1212
Query: 508 --------PLPPLAGGEAFPFPSP----EQGLALSGAGFPGMLGALPLP--------LSL 547
PL PL + P G A+SG + +L +
Sbjct: 1213 EAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEE 1272
Query: 548 GQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPP 607
QP S L G PP G PPL+P + PS+ L P PP
Sbjct: 1273 KQPEMKSGFMASFLDFLKSGKRHPPLYQ-----AGLTPPLSPPKSVPPSVPARGLQPQPP 1327
Query: 608 SDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL 667
+ P PPS L A + EG G P L L
Sbjct: 1328 ATPAVP-HPPPSGAFG-----LGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFS 1381
Query: 668 SAPPTLIALN-------SALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGAS 720
S +A N S+ ++A DPP P S P GPP + P
Sbjct: 1382 SDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT---STPD-GPPLAPAAAVPGPPPLP 1437
Query: 721 SLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPG 780
L A SN P LL + T P P PP P
Sbjct: 1438 GLPSANSNGTPEPPLLE---------EKPPPTPPPAPTPQPQPPPPP------------- 1475
Query: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS 840
PPP SP + + PP P P PP P+ P PA PL+A +
Sbjct: 1476 ---PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532
Query: 841 PDPPVPEL 848
P P PEL
Sbjct: 1533 PSPEDPEL 1540
Score = 82.8 bits (203), Expect = 1e-15
Identities = 232/919 (25%), Positives = 287/919 (31%), Gaps = 192/919 (20%)
Query: 129 GASPQMFHTVSPGPPSARPPCRVPPT--TPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFP 186
G P PGPP PP R PT L + S Q + G P
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPP 277
Query: 187 PRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPP 246
P A P + + R + P PPPPPA +L + G + S ++L P
Sbjct: 278 PERALP---RQDTVIKHYQRPASAQPPPPPPPAHALQ-HYLSCGGSYPSMGHRANLACSP 333
Query: 247 APHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGG 306
SP A P PS G A+ P + G GG
Sbjct: 334 LGGGEPSP----------GAGEPSKAGPSGATAGASGRATGPEAAGG--------GGAGG 375
Query: 307 A-----PTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSS---- 357
P ++ PG AAA P PP ST + P+A++++
Sbjct: 376 GGGGYRPIIQSPGYK--TGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS 433
Query: 358 --------SLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEP----- 404
+ P Q + P + G G P PQP S P P
Sbjct: 434 GAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLAT 493
Query: 405 SQPILPSVL-----SLLGLPTPGP-SHSDG----SFNLLGSDAHLPP---------PPTL 445
Q P L + G P PGP +HS G S +L S H P P +L
Sbjct: 494 CQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
Query: 446 SSGSPPQPRHPIQP--SLPGTTSGSLSSVPGAPAPPAAS---KAPVVPSPVLQSPSEGLG 500
G P H I+P S P T PGAP +S AP + P S + G G
Sbjct: 554 GGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG 613
Query: 501 ----------MGAGPACPLPPLAGGEAF------PFPSPEQGLALSGA-GFPGMLGALPL 543
+ AGP P E F PSP + SGA G G GA
Sbjct: 614 GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPR---TSGADGLVGEDGAADA 670
Query: 544 PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLL 603
LG +GG G PP P LA +P+ L S++
Sbjct: 671 SKGLGG---------------SGGAGGPPGTPY---------ELAKEDPQRYHL--QSVI 704
Query: 604 PPPPSDLLPPPSAPPSNLLASFLPLLALGPTAG----DGEGSAEGAGGPSGEPFSGLGDL 659
S L + L L GP G +G ++ G +
Sbjct: 705 RTSAS--LDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQK 762
Query: 660 SPLLFPPL--SAPPT----LIALNSALLAATLDPPSGTPPQ--PCVLS-APQPGPPTSSV 710
SP PP S PT L+ L L PP PPQ P VLS AP P P S V
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPP---PPQLLPSVLSHAPSPSPSASKV 819
Query: 711 TTATTDPGASSLGKAPSNSGRPPQLLSPL-LGASLLG-DLSSLTSSPGALP-SLLQPPGP 767
+P P PP PL L A L L SP P L PPG
Sbjct: 820 GVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA 879
Query: 768 LLSGQLGLQLLPGG----GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPES----PA 819
+ L+ LP G PP SE P P+ +AP P + P
Sbjct: 880 MQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSP---SPQGTKAPRFVPLTSICFPD 936
Query: 820 SALEPE---------------------PARPPLSALAPPHGSPDPPVPELLTGRGSGKRG 858
S L+ E A PP P G+ PP P G G
Sbjct: 937 SLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPG 996
Query: 859 RRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGE 918
R G G P G P E L G ++ P +
Sbjct: 997 RASGA------GPETPGLGLDPNKPPE-----LPSTVNAEPLGLIQSGPHQ--------- 1036
Query: 919 LAEGGAEPKDPPPPGPHSE 937
A P PPPP P SE
Sbjct: 1037 -AAPPPPPPPPPPPAPASE 1054
Score = 82.8 bits (203), Expect = 1e-15
Identities = 209/820 (25%), Positives = 268/820 (32%), Gaps = 179/820 (21%)
Query: 140 PGPPSARPP-----CRVPPTTPLNG-----------GPGS----LPPEPPSVSQAF---P 176
P PPS PP C+ L G GP + LP PS+S + P
Sbjct: 480 PQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSP 539
Query: 177 TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAI-SLNAPSYNWGAALRS 235
L+G GG + P + GG +SP + R PA PP + S AP + L S
Sbjct: 540 ALSGHGGGWGP---SSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLAS 596
Query: 236 S--LVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNN------LPAHPGPASQ 287
+ L P GS A D S+ L P PP+ L H A
Sbjct: 597 APFLAPPGAGSYAAGAGGYKGKGDG-----SELLAGPGGPPAERTEDEEFLIQHLLQAPS 651
Query: 288 PPVSSATMHLPLVLGP------LGGAPTVEGPGAPPF-----------------LASSLL 324
PP +S L G LGG+ GP P+ ++SL
Sbjct: 652 PPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLD 711
Query: 325 SAAAKAQHPPLPPPSTLQ------GRRPRAQAPSASHSSSLRPS-----QRRPRRPPTVF 373
A A L + G P A S H + Q+ P PP
Sbjct: 712 EGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTA 771
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLL 433
+ + TP A P P LP P +LPSVLS P+P PS S +LL
Sbjct: 772 QSTQ----PTPHGLLLEAGGP-DLPLVLPPPPPQLLPSVLS--HAPSPSPSASKVGVHLL 824
Query: 434 ------GSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487
G+ PPPP PP P P+Q + G + P P S P
Sbjct: 825 EPATRDGAPQPPPPPP------PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPG 878
Query: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGE----AFPFPSPEQGLALSGAGFPGM--LGAL 541
L E L G PP + G+ A+ PSP+ G P L ++
Sbjct: 879 AMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ------GTKAPRFVPLTSI 932
Query: 542 PLPLSLGQPPPSPLL--NHSLFGVLTGG-----GGQPPPEPLLPPPGGPGPPLAPG--EP 592
P SL Q +FG GG G PPE P G GPP P +P
Sbjct: 933 CFPDSLLQDEERSFFPTMEEMFG---GGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDP 989
Query: 593 EGPSL--LVASLLPPPPSDLLPPPSAP--PSNLLASFLPLLALGP--TAGDGEGSAEGAG 646
GP + P P L P P PS + A L L+ GP A
Sbjct: 990 YGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPP 1049
Query: 647 GPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPP 706
P+ EP GL SP+ + P L+ +S L DPP TP + L A +
Sbjct: 1050 APASEPKGGL--TSPIFCS--TKPKKLLKTSSFHLLRRRDPPFQTPKK---LYAQE---- 1098
Query: 707 TSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLL---GASLLGDLSSLTSSPGALPSLLQ 763
+ A N R P L+S S LGD+ +PG
Sbjct: 1099 ---YEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPG------- 1148
Query: 764 PPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALE 823
P GP G+ + G PP P + P +
Sbjct: 1149 PDGPRRRGRKPTKAKRDG----------------------PPRPRGRPRIRPLEVPTTAG 1186
Query: 824 PEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGG 863
P A P P G GRG G++ GG
Sbjct: 1187 PASASTPTDGAKKPRG----------RGRGRGRKAEEAGG 1216
Score = 81.3 bits (199), Expect = 4e-15
Identities = 227/956 (23%), Positives = 306/956 (32%), Gaps = 210/956 (21%)
Query: 126 PGEGASPQMFHTVSPGPPSARP-----PCRVP---PTTPLNGGPGSLPPEPPSVSQAFPT 177
P GA P PGPP+ P P R P TP G + PPE PS A P
Sbjct: 974 PKAGAGPP------PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 178 ---LAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPA--------------------- 213
+GP PP P P +P P+G SP
Sbjct: 1028 GLIQSGPHQAAPP---PPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRR 1084
Query: 214 -PPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA--PHASSSPPSDPPLFHCSDALTPP 270
PP L A Y + A + VP+D+ P P SS S P L D P
Sbjct: 1085 DPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCP 1144
Query: 271 PLPPSNN------------LPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPF 318
P P + P P +P + + +P GP + +G P
Sbjct: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRP--LEVPTTAGPASASTPTDGAKKPRG 1202
Query: 319 LASSLLSAAAKAQHPPLPP--PSTLQGRRPRA---------QAPSASHSSSLRPSQRRPR 367
A +A L P P ++ P+A A S + +SL S R +
Sbjct: 1203 RGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREK 1262
Query: 368 RPPTVFRLLEGRGPQ--------------TPRRSRPRAPAPVPQPFSLPE------PSQP 407
+ + +E + P+ + +R P A + P S P+ P++
Sbjct: 1263 IEAKI-KEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARG 1321
Query: 408 ILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQP------SL 461
+ P + +P P PS + G LG L G P + + +L
Sbjct: 1322 LQPQPPATPAVPHPPPSGAFG----LGGALEAAESEGLGLGCPSPCKRLDEELKRNLETL 1377
Query: 462 PGTTSGSLSSVPGAP--APPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFP 519
P +S SV +S + P L P + PPLA A P
Sbjct: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDG------PPLAPAAAVP 1431
Query: 520 FPSPEQGLALS---GAGFPGMLGALP------LPLSLGQPPPSPLLNHSLFG----VLTG 566
P P GL + G P +L P P QPPP P ++
Sbjct: 1432 GPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491
Query: 567 GGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP------PSN 620
PPP PL PPP PP P P P A L PP P P P P +
Sbjct: 1492 TPSSPPPPPLPPPP----PPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLH 1547
Query: 621 LLASFLPLLALGPTAGD-GEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSA--PPTLIALN 677
L G T + GE EG E D+ L + PP + +
Sbjct: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQ 1607
Query: 678 SALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLS 737
ALL Q C S + LG R +L
Sbjct: 1608 KALLQKFTPEIKDGQRQFCATS--------------------NYLGYFGDAKNRYQRLYV 1647
Query: 738 PLLGASLLGDLSSLTSSPGALPSLLQPPGPLL-SGQLGLQLLPGGGAPPPLSEASSPLAC 796
L D + A +PP P+ SGQ + GG + PP
Sbjct: 1648 KFLENVNKKDYVRVC----ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPP---------- 1693
Query: 797 LLQSLQIPPEQPEAPCLPP--ESP-ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRG 853
P+AP PP E+P + E P + P +A+ P P P P LL
Sbjct: 1694 -----------PKAPAPPPKPETPEKTTSEKPPEQTPETAMPEP---PAPEKPSLLRPVE 1739
Query: 854 SGK------RGRRGGGGLRGING-EARPARG---RKPGSRREPGRLALKWGTRGGFNGQM 903
K RG R G R +G + RP R +P + R P K +
Sbjct: 1740 KEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTK--------VKA 1791
Query: 904 ERSPRRTHHW--QHNGELAEGGAEP----KDPPPPGPHSEDLKVPPGVVRKSRRGR 953
E P++ W + G GG P PG SED + PG + K+R R
Sbjct: 1792 EPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMR 1847
Score = 80.5 bits (197), Expect = 7e-15
Identities = 193/766 (25%), Positives = 253/766 (33%), Gaps = 136/766 (17%)
Query: 249 HASSSPPSDPPLFHCSDALT---PPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG 305
HA S+ P D + + AL P P P +++L + + P MH P GP
Sbjct: 78 HAGSAGP-DASVMNLISALESRGPQPGPSASSLLSQ----FRSPSWQTAMHTP---GPTE 129
Query: 306 GAPTVEGPGAPPFLASSLLSAAAKAQHP------PLPPPSTLQGRRPRAQAPSASHSSSL 359
+ PG+ F +SS LSA QHP P P PS+L + P P+ S
Sbjct: 130 LFISGALPGSSTFPSSSALSAY---QHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPH 186
Query: 360 RPSQRRPRRPPTV-----FRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
+P + PTV F L G G P P P P P LP+ +
Sbjct: 187 DVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFN 246
Query: 415 LLGLPTPGPSHSDGSF-NLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVP 473
LL + + ++ S L P PP PP+ P Q ++ S+ P
Sbjct: 247 LLASSSAAAAAAEQSSPQLYNFSGAAPGPP------PPERALPRQDTVIKHYQRPASAQP 300
Query: 474 GAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAG 533
P PPA + + +G A AC PL GGE PSP GAG
Sbjct: 301 PPPPPPAHALQHYLSCG---GSYPSMGHRANLACS--PLGGGE----PSP-------GAG 344
Query: 534 FPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPE 593
P G P G GGG P++ PG G
Sbjct: 345 EPSKAGPSGATAGASGRATGP----EAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
Query: 594 GPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPF 653
G + PPPP P GP A G A GAGG G+ +
Sbjct: 401 G-----GATRPPPPRSTATPKCQSLG------------GPAAAYATGKASGAGGAGGQAY 443
Query: 654 SGLGDLSPLLFPPL------SAPPTLIALNSALLAATLDPPSGTPPQPC----------- 696
S G LL P ++ + PPSG PP
Sbjct: 444 SP-GQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQL 502
Query: 697 ------VLSAPQPGPPTSSVTTATTDPGAS-SLGKAPSNSGRPPQLLSPLLGASLLGDLS 749
V P PGP S T P S S G +P+ SG LG S
Sbjct: 503 QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPS 562
Query: 750 SLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSE-ASSPLACLLQSLQIPPEQP 808
+ + P+ +PPG G G L + P L+ + A + +
Sbjct: 563 HIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGS 622
Query: 809 EAPCLPPESPASALEPEP--ARPPLSALAPPHGS-PDPPVPELLTGRGSGKRGRRGGGGL 865
E P PA E E + L A +PP S D V E G +G G GG
Sbjct: 623 ELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGE--DGAADASKGLGGSGGA 680
Query: 866 RGING------EARPARG------RKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHW 913
G G + P R R S E AL+ G G + ++ P R
Sbjct: 681 GGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGL--GRLKEKKKGPER---- 734
Query: 914 QHNGELAEG----------GAEP------KDPPPPGPHSEDLKVPP 943
GE EG GA+ K PPPP P ++ + P
Sbjct: 735 --GGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTP 778
Score = 70.9 bits (172), Expect = 6e-12
Identities = 161/693 (23%), Positives = 221/693 (31%), Gaps = 171/693 (24%)
Query: 77 DPLAPVTPGGAGVGPASEEDMTKLCNHRRKAV--AMATLYRSMETTCSHSS--------- 125
+PL P PG GVGP + E +R + A + + + C S
Sbjct: 888 EPLPPA-PGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSF 946
Query: 126 ---------------------PGEGASPQMFHTVSPGPPSARP-----PCRVP---PTTP 156
P + P+ PGPP+ P P R P TP
Sbjct: 947 FPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETP 1006
Query: 157 LNGGPGSLPPEPPSVSQAFP---TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPA 213
G + PPE PS A P +GP PP P P +P P+G SP
Sbjct: 1007 GLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP---PPPPPPPPPAPASEPKGGLTSPI 1063
Query: 214 ----------------------PPPPPAISLNAPSYNWGAALRSSLVPSDLGSPP--APH 249
PP L A Y + A + VP+D+ P P
Sbjct: 1064 FCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPD 1123
Query: 250 ASSSPPSDPPLFHCSDALTPPP------------LPPSNNLPAHPGPASQPPVSSATMHL 297
SS S P L D PP P P P +P + + +
Sbjct: 1124 LVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRI--RPLEV 1181
Query: 298 PLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPP--PSTLQGRRPRA------- 348
P GP + +G P A +A L P P ++ P+A
Sbjct: 1182 PTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTS 1241
Query: 349 --QAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQ--------------TPRRSRPRAP 392
A S + +SL S R + + + +E + P+ + +R P
Sbjct: 1242 SGDAISGTDHNSLDSSLTREKIEAKI-KEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQ 1300
Query: 393 APVPQPFSLPE------PSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS 446
A + P S P+ P++ + P + +P P PS + G LG L
Sbjct: 1301 AGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFG----LGGALEAAESEGLG 1356
Query: 447 SGSPPQPRHPIQ------PSLPGTTSGSLSSV-------PGAPAPPAASKAPVVPSPVLQ 493
G P + + +LP +S SV + +A P + P
Sbjct: 1357 LGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT 1416
Query: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA---LSGAGFPGMLGALPLPLSLGQP 550
S +G PPLA A P P P GL +G P +L P P P
Sbjct: 1417 STPDG-----------PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465
Query: 551 PPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPP----LAPGEPEGPSLLVASLLPPP 606
P P QPPP P P P P PP P P P L PPP
Sbjct: 1466 TPQP---------------QPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP----PPP 1506
Query: 607 PSDLLPPPSAPPSNLLASFLPLLALGPTAGDGE 639
P+ PPP PP+ + P P+ D E
Sbjct: 1507 PAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 100 bits (248), Expect = 9e-21
Identities = 193/782 (24%), Positives = 269/782 (34%), Gaps = 154/782 (19%)
Query: 125 SPGEGASPQM------FHTVSPGPPSARPPCRVPP---------------TTPLNGGPGS 163
+PG G+SP + H +P P +P +PP T + G PG+
Sbjct: 328 APGLGSSPLVPAPNVILHR-TPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGA 386
Query: 164 LPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS-- 221
LP +P + AG G P P+ ++ + P + P PP A+S
Sbjct: 387 LPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKP 446
Query: 222 LNAPSYNWGAAL--------------------------RSSLVPSDLG----SPPAPHAS 251
++ N G+++ + S +P+++G + APH
Sbjct: 447 MSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTG 506
Query: 252 SSPPSDPPLFHCSDA----LTPPPLPPSNNLPAH-----PGPASQPPVSSATMHLPLVLG 302
++P L + + A L P P S AH P QP + + L
Sbjct: 507 GQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSL 566
Query: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362
P P GP A L L +A A P +Q P A A+ +++P+
Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNT--PDGLVQPATPAAATGEAAPVLTVQPA 624
Query: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG 422
P+ PP V L G Q P+ +P AP PQ + P+ + P P+PG
Sbjct: 625 ---PQAPPAVSTPLP-LGLQQPQAQQP-PQAPTPQAAAPPQATTP----------QPSPG 669
Query: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGSP----PQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
+ S +LG P L+ S PQ R S G +SV + P
Sbjct: 670 LASSPEKI-VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP 728
Query: 479 PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA--LSGAGFPG 536
PA AP P G G GP P +A P P+P+ A L G G P
Sbjct: 729 PAQDPAPATPV--------AKGAGLGPQAP-----DSQASPAPAPQIPAAAPLKGPG-PS 774
Query: 537 MLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596
+LP LG P P P P PP P P + P PS
Sbjct: 775 SSPSLPHQAPLGDSPHLP-----------------SPHPTRPPSRPPSRPQSVSRP--PS 815
Query: 597 LLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALG--PTAGDGEGSAEGAGGPSGEPFS 654
PP PPP APP+ L F+ LG P A + +A G P P S
Sbjct: 816 --------EPPLHPCPPPQAPPT-LPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 655 GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTAT 714
+ PL P L +++ A+ S P P PP+ +
Sbjct: 867 QPPE------GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP 920
Query: 715 TDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLG 774
T P L P+ PP P + +L L Q P ++
Sbjct: 921 TPPPTLHLVPEPAAPPPPP----PRTFQMVTTPFPALPQPKALLERFHQVPSGII----- 971
Query: 775 LQLLPGGGAPPPLSEAS-----SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARP 829
LQ GG P + S SP A +L S Q P P A P +PA A P
Sbjct: 972 LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTA---PSHAPAPAPMAATGLP 1028
Query: 830 PL 831
PL
Sbjct: 1029 PL 1030
Score = 97.1 bits (240), Expect = 8e-20
Identities = 130/476 (27%), Positives = 167/476 (35%), Gaps = 90/476 (18%)
Query: 118 ETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTT-----PLNGGPGSLPPEPPSVS 172
+ T SPG +SP+ V PPSA P + + P L E P +S
Sbjct: 660 QATTPQPSPGLASSPEKI--VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS 717
Query: 173 -QAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGA 231
A ++ P P A PV G P+ +P+PAP P A L P +
Sbjct: 718 VPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP 777
Query: 232 ALRSSLVPSDLGSPPAPHAS-------------SSPPSDPPLFHCSDALTPPPLP---PS 275
+L D P+PH + S PPS+PPL C PP LP
Sbjct: 778 SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837
Query: 276 NNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPL 335
N P PAS P APT GP PP S P L
Sbjct: 838 QNQLGVPPPASNP------------------APTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Query: 336 PPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRP-RAPAP 394
PP ST S++ +SS S R P P+ F+L Q P P ++P P
Sbjct: 880 PPSST-----------SSAVASSSETSSRLPAPTPSDFQL------QFPPSQGPHKSPTP 922
Query: 395 VPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL-------SS 447
P +PEP+ P P + + TP P+ LP P L S
Sbjct: 923 PPTLHLVPEPAAPPPPPPRTFQMVTTPFPA--------------LPQPKALLERFHQVPS 968
Query: 448 GSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS--KAPVVPSPVLQSPSEGLGMGAGP 505
G Q + P+ P T S+ G PAAS + PS +PS
Sbjct: 969 GIILQNKAGGAPAAPQT-----STSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023
Query: 506 ACPLPPL--AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHS 559
A LPPL A +AF P +A + + PG L L P L S
Sbjct: 1024 ATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPS 1079
Score = 96.7 bits (239), Expect = 1e-19
Identities = 194/788 (24%), Positives = 258/788 (32%), Gaps = 135/788 (17%)
Query: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHT 137
P PVT AGV P V L ++ TT + +S GA T
Sbjct: 269 PSEPVTLASAGVSPQGAG-----------LVIQKNLSAAVATTLNGNSVFGGAGAASAPT 317
Query: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT--LAGPGGLFPPRLADPVPS 195
G PS +P P G L P P + PT P G+ PP+L P
Sbjct: 318 ---GTPSGQPLAVAPGL-----GSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPK 369
Query: 196 GGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255
+ + L P P P A N G A ++ + L PAP ++
Sbjct: 370 PFAPAGATLTIQGEPGALPQQPKAPQ-NLTFMAAGKAGQNVV----LSGFPAPALQANVF 424
Query: 256 SDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGA 315
PP A PP S + H V A LP G PGA
Sbjct: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP-------GQNQFLLPGA 477
Query: 316 PPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRP--SQRRPRRPPTVF 373
P LSA P+ + G+ A AP P + + P ++
Sbjct: 478 PAVQLPQQLSAL----------PANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527
Query: 374 RLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT---PGPSHSDGSF 430
+L P A P + +P+ +P L+ LPT P P+ +
Sbjct: 528 PVL------APHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATT 581
Query: 431 NLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSV----PGAPAPPAASKAPV 486
L G LPP +P +QP+ P +G + V P APPA S
Sbjct: 582 VLQG--VTLPPSAVAMLNTPDGL---VQPATPAAATGEAAPVLTVQPAPQAPPAVS---- 632
Query: 487 VPSPV-LQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPL 545
P P+ LQ P P P P A P P GLA S P +
Sbjct: 633 TPLPLGLQQPQAQ----QPPQAPTPQAAAPPQATTPQPSPGLASS-----------PEKI 677
Query: 546 SLGQPP---PSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASL 602
LGQPP P+ +L + P E P GP L+ P+ ++ S
Sbjct: 678 VLGQPPSATPTAILTQDSLQMFL------PQERSQQPLSAEGPHLSV-----PASVIVSA 726
Query: 603 LPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG-PSGEPFSGLGDLSP 661
PPP D P P+ P + LGP A D + S A P+ P G G S
Sbjct: 727 -PPPAQD--PAPATPVAKGAG-------LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSS 776
Query: 662 LLFP---PLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPG 718
P PL P L + + PPS P +P +S P PP P
Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTR------PPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPT 830
Query: 719 ASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778
+ + G PP +P + P P P GPL
Sbjct: 831 LPGIFVIQNQLGVPPPASNP-------APTAPGPPQPPLRPQSQPPEGPL---------- 873
Query: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838
P PP S +S+ + S ++P P L P+ P PP L P
Sbjct: 874 PPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ-FPPSQGPHKSPTPPPTLHLVPEP 932
Query: 839 GSPDPPVP 846
+P PP P
Sbjct: 933 AAPPPPPP 940
Score = 88.2 bits (217), Expect = 4e-17
Identities = 205/830 (24%), Positives = 274/830 (33%), Gaps = 207/830 (24%)
Query: 148 PCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRL------------------ 189
P ++P P +GG G P A AGP LFP
Sbjct: 128 PFQLPTLQPADGGAG-----PTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALV 182
Query: 190 --ADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSD------ 241
D V S P P G P P L S A L P
Sbjct: 183 PPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPV 242
Query: 242 --LGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSA---TMH 296
L +P + + P L + P L + P G Q +S+A T++
Sbjct: 243 MALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLN 302
Query: 297 LPLVLGPLGGA--PTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSAS 354
V G G A PT G P +A L S+ P +P P+ + R P
Sbjct: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSS------PLVPAPNVILHRTPT------- 349
Query: 355 HSSSLRPSQRRPRR--PPTVFRLLEGRGPQTPRRSRPRAPAPVP-----QPFSLPEPSQP 407
P Q +P PP +++L TP+ P APA +P +LP+ QP
Sbjct: 350 ------PIQPKPAGVLPPKLYQL-------TPK---PFAPAGATLTIQGEPGALPQ--QP 391
Query: 408 ILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHL--PPPPTLSSGSPPQPRH---------- 455
P L+ + G + F A++ PP T + +PPQP
Sbjct: 392 KAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHL 451
Query: 456 ---------PIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPV------LQSPSEGLG 500
P Q LPG L PGAPA + +P+ V +P G
Sbjct: 452 LNQGSSIVIPAQHMLPGQNQFLL---PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQ 508
Query: 501 MGAGPACPLPPLAGGEAF-PFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHS 559
+ A P LAG + P +P SGA +L A P+ +GQP +
Sbjct: 509 LIANPILTNQNLAGPLSLGPVLAPH-----SGAHSAHILSAAPI--QVGQP--------A 553
Query: 560 LFGVLTGGGGQPPPEPLLPPPGGPG----------PPLAPGEPEGPSLLVASLLPP---- 605
LF + P P P GP PP A P LV P
Sbjct: 554 LFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATG 613
Query: 606 ---PPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA--EGAGGPSG---EPFSGLG 657
P + P P APP+ +++ LPL P A + + A P +P GL
Sbjct: 614 EAAPVLTVQPAPQAPPA--VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLA 671
Query: 658 DLSP---LLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTAT 714
SP +L P SA PT I +L + P QP P P S + +A
Sbjct: 672 S-SPEKIVLGQPPSATPTAILTQDSL---QMFLPQERSQQPLSAEGPHLSVPASVIVSA- 726
Query: 715 TDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL-----LQPPGPLL 769
P + P GA L +SP P + L+ PGP
Sbjct: 727 -----------PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775
Query: 770 SGQLGLQLLPGGGAP---------PPLSEASSPLACLLQSLQIPPEQPEA-PCLPPESPA 819
S L Q P G +P PP S P QS+ PP +P PC PP++P
Sbjct: 776 SPSLPHQA-PLGDSPHLPSPHPTRPPSRPPSRP-----QSVSRPPSEPPLHPCPPPQAPP 829
Query: 820 SA---------------------LEPEPARPPLSALAPPHGSPDPPVPEL 848
+ P P +PPL + P P PP P L
Sbjct: 830 TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/237 (27%), Positives = 87/237 (36%), Gaps = 36/237 (15%)
Query: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPG-GLFPPRLADPVPS 195
T+ P RPP PPT +N G++ PP+ + P P P R
Sbjct: 1339 TLKVAEPPPRPPPPPPPTGQMN---GTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENV 1395
Query: 196 GGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDL------GSPPAPH 249
GG +P P G A +P P PA A S G + V +L G PP P
Sbjct: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATS---GLIRELAAVEDELYQRMLKGPPPEPA 1452
Query: 250 ASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS-------ATMHLPLVLG 302
AS++ + P + P LPP+ + Q SS T HL +
Sbjct: 1453 ASAAQGTGDPDWEA------PGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAID 1506
Query: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSL 359
+ + PG P + AA A P PPP RP A PS SH+ L
Sbjct: 1507 SI--LNLQQAPGRTP---APSYPHAASAGTPASPPPL----HRPEAYPPS-SHNGGL 1553
Score = 44.7 bits (104), Expect = 4e-04
Identities = 73/266 (27%), Positives = 94/266 (35%), Gaps = 56/266 (21%)
Query: 438 HLPPPP--TLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
H PPPP TL PP PR P P G +G++ P P A + P
Sbjct: 1331 HQPPPPPATLKVAEPP-PRPPPPPPPTGQMNGTVDH----PPPAAPERKP---------- 1375
Query: 496 SEGLGMGAGPACPLPPL-------AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLG 548
+G P CP PL GG P +P G A G+ P L A + G
Sbjct: 1376 -----LGTAPHCPRLPLRKTYRENVGGPGAPEGTP-AGRARGGS--PAPLPAKVDEATSG 1427
Query: 549 QPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPP--LAPGEP-------EGPSLLV 599
+ L+ + G PPPEP G G P APG P E P +
Sbjct: 1428 LIRELAAVEDELYQRMLKG---PPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQ 1484
Query: 600 ASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDL 659
AS P D +L ++ +L L G + +G P S
Sbjct: 1485 ASFSSDSPQD-----DTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPAS----- 1534
Query: 660 SPLLFPPLSAPPTLIALNSALLAATL 685
P L P + PP+ + N L A TL
Sbjct: 1535 PPPLHRPEAYPPS--SHNGGLGARTL 1558
Score = 39.7 bits (91), Expect = 0.014
Identities = 86/377 (22%), Positives = 130/377 (34%), Gaps = 75/377 (19%)
Query: 193 VPSGGSSSPRFLP-----RGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
+P SS LP +AP + PPP + + GA S+ + S +
Sbjct: 1210 LPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
Query: 248 PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGA 307
+SSS + DA P+P N P A + + L L + G
Sbjct: 1270 SSSSSSSAASS-----LDADEDGPMPSRNRPPIKTYEAR------SRIGLKLKIKQEAG- 1317
Query: 308 PTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAP-----------SASHS 356
L+ + + A H P PPP+TL+ P + P + H
Sbjct: 1318 -----------LSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHP 1366
Query: 357 SSLRPSQRR-------PRRP--PTVFRLLEGRG-PQTPRRSRPRAPAPVPQPFSLPEPSQ 406
P ++ PR P T + G G P+ R R +P P P + E +
Sbjct: 1367 PPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATS 1426
Query: 407 PILPSVLS--------LLGLPTPGP--SHSDGSFNLLGSDAHLPPPPTLSSGSPPQPR-- 454
++ + + +L P P P S + G+ + LPP S SP +
Sbjct: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQAS 1486
Query: 455 ----HPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLP 510
P +L ++ S+ P + AP P + S G PA P P
Sbjct: 1487 FSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYP----HAASAGT-----PASP-P 1536
Query: 511 PLAGGEAFPFPSPEQGL 527
PL EA+P S GL
Sbjct: 1537 PLHRPEAYPPSSHNGGL 1553
Score = 30.4 bits (67), Expect = 8.7
Identities = 46/185 (24%), Positives = 61/185 (32%), Gaps = 34/185 (18%)
Query: 676 LNSALLAATLDPPSGTPPQPCVLSA------PQPGPPTSSVTTATTD------PGASSLG 723
L+ + LDP PP P L P P PP + T D P LG
Sbjct: 1318 LSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377
Query: 724 KAP------------SNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSG 771
AP N G P G + G + L + S L +
Sbjct: 1378 TAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVED 1437
Query: 772 QLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPL 831
+L ++L G PPP P A Q P EAP LPP + P+ +
Sbjct: 1438 ELYQRMLKG---PPP-----EPAASAAQGTGDP--DWEAPGLPPAKRRKSESPDVDQASF 1487
Query: 832 SALAP 836
S+ +P
Sbjct: 1488 SSDSP 1492
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 99.8 bits (247), Expect = 1e-20
Identities = 144/502 (28%), Positives = 183/502 (36%), Gaps = 108/502 (21%)
Query: 130 ASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRL 189
A P P P + P PP+TP+ GPG P PP G PP L
Sbjct: 690 ACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQ--PAPP-------------GQQPPPL 734
Query: 190 ADPVPSGGSSSPRFLPRGNAPSPA----PPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
A P P LP+ AP P P PP AP+ GA + L P +
Sbjct: 735 AQPTP---------LPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP--AQLKPLQMPQA 783
Query: 246 PAPHASSSPPSDPPLFHCSDALTPP--PLPPSNNL-PAHPG--PASQPPVSSATMHLPLV 300
P + PP PP+ + PP PL + L PA P A+ PPV P V
Sbjct: 784 PLQPLAQVPPQMPPI-----PVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAV 838
Query: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360
+ P AP P A P +L A K HPP AP A ++
Sbjct: 839 ILPSLAAPL---PPASP----ALPLQAVKLPHPP--------------GAPLAMPCRTIV 877
Query: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT 420
P+ P LL P S A A + P QP+ P+ + PT
Sbjct: 878 PN------APATIPLLAVAPPGVAALSIHSAVAQL--------PGQPVYPAAFPQMA-PT 922
Query: 421 ---PGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPA 477
P P H+ + LPP PTL PPQP P QP+LP P P
Sbjct: 923 DVPPSPHHTVQNMRATPPQPALPPQPTL----PPQPVLPPQPTLP--------PQPVLPP 970
Query: 478 PPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGM 537
P PV+P + P L PA P+ P E PEQ + G +
Sbjct: 971 QPTRPPQPVLPPQPMLPPQPVL--PPQPALPVRP----EPLQPHLPEQAAPAATPGSQIL 1024
Query: 538 LGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSL 597
LG P P ++ P + VL+ P PE LLP P L P P +
Sbjct: 1025 LGH-PAPYAVDVAAQVPTVPVPPAAVLS----PPLPEVLLP----AAPELLPQFPSSLAT 1075
Query: 598 LVASL--LPPPPSDLLPPPSAP 617
+ AS+ +P + LLPP + P
Sbjct: 1076 VSASVQSVPTQTATLLPPANPP 1097
Score = 94.0 bits (232), Expect = 6e-19
Identities = 179/645 (27%), Positives = 223/645 (34%), Gaps = 129/645 (20%)
Query: 141 GPPSARPPCRVPPTTPLNGG-PGSLPPEPPSVSQ-----AFPTLA---GPGGLFPPRLAD 191
GPP P +V T G PG PE P Q PT A F
Sbjct: 566 GPPV---PLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGS 622
Query: 192 PVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS------DLGSP 245
V S SS + + G+ AP P + +P + G L SL PS +P
Sbjct: 623 TVYSDSQSSQQSVMLGSLADAAPSPAQCVC--SPPVSEGPVLPQSL-PSLGAYQQPTAAP 679
Query: 246 PAPHASSSPPSDPPLF--HCSD---ALTPPPLPPSNNLPAHPG----PASQPPVSSATMH 296
P S P+ PP H D + P PPS +P PG P QPP +
Sbjct: 680 GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP 739
Query: 297 LPLVLGPLGGAPTVE-GPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASH 355
LP VL P P P PP+LA + A AQ PL P +P AQ P
Sbjct: 740 LPQVLAPQPVVPLQPVPPHLPPYLAPAS-QVGAPAQLKPLQMPQA--PLQPLAQVPPQMP 796
Query: 356 SSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRA---PAPVPQPFSLPEPSQPILPSV 412
+ P P T ++G P P P A P P PQ FS ILPS+
Sbjct: 797 PIPVVP-------PITPLAGIDGLPPALP--DLPTATVPPVPPPQYFS----PAVILPSL 843
Query: 413 LSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP-PQPRHPIQPSLPGTTSGSLSS 471
+ LP P+ L LP PP G+P P I P+ P T
Sbjct: 844 AA--PLPPASPA-------LPLQAVKLPHPP----GAPLAMPCRTIVPNAPAT------- 883
Query: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPF---PSPEQGLA 528
+P P A + S V Q P + P+ P A + P PSP +
Sbjct: 884 IPLLAVAPPGVAALSIHSAVAQLPGQ----------PVYPAAFPQMAPTDVPPSPHHTV- 932
Query: 529 LSGAGFPGMLGALPLPLSLGQP--PPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPP 586
M P P QP PP P+L PP+P LPP P P
Sbjct: 933 ------QNMRATPPQPALPPQPTLPPQPVL---------------PPQPTLPPQ--PVLP 969
Query: 587 LAPGEPEGPSLLVASLLPPPPSDLLPPPSAPP--SNLLASFLPLLALGPTAGDGEGSAEG 644
P P P L +LPP P +LPP A P L LP A P A G G
Sbjct: 970 PQPTRPPQPVLPPQPMLPPQP--VLPPQPALPVRPEPLQPHLPEQA-APAATPGSQILLG 1026
Query: 645 AGGPSGEPFSGLGDLSP-----LLFPP-----LSAPPTLIALNSALLAATLDPPSGTPPQ 694
P + P +L PP L A P L+ + LA P Q
Sbjct: 1027 HPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQ 1086
Query: 695 PCVL----SAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQL 735
L + P PG P + T + + ++ +PP L
Sbjct: 1087 TATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGL 1131
Score = 92.0 bits (227), Expect = 2e-18
Identities = 137/506 (27%), Positives = 180/506 (35%), Gaps = 90/506 (17%)
Query: 377 EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS-HSDGSFN---- 431
+ RGP P + + A QP PEP +P L LPT S SD +F+
Sbjct: 563 KARGPPVPLQVQVTYHAQAGQP-GPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQG 621
Query: 432 --------------LLGSDAHLPPPPTLSSGSPPQPRHPIQP-SLPGTTSGSLSSVPGAP 476
+LGS A P P SPP P+ P SLP G+ AP
Sbjct: 622 STVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSL--GAYQQPTAAP 679
Query: 477 APPAAS-KAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFP 535
P S AP P P LQ M P P P + P P+ G G P
Sbjct: 680 GLPVGSVPAPACP-PSLQQHFPDPAMSFAPVLPPP------STPMPT--------GPGQP 724
Query: 536 GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEG- 594
G P PL+ P P L P PL P P P LAP G
Sbjct: 725 APPGQQPPPLAQPTPLPQVL-------------APQPVVPLQPVPPHLPPYLAPASQVGA 771
Query: 595 PSLLVASLLPPPPSDLLP--PPSAPPSNLLASFLPLLALG--PTAGDGEGSAEGAGGPSG 650
P+ L +P P L PP PP ++ PL + P A +A P
Sbjct: 772 PAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPP 831
Query: 651 EPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP-PQPCVLSAPQPGPPTSS 709
+ FS ++ P L+AP + L A L P G P PC P P +
Sbjct: 832 QYFS-----PAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA--PATI 884
Query: 710 VTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASL------------LGDLSSLTSSPGA 757
A PG ++L + + P Q + P + + ++ + P
Sbjct: 885 PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPAL 944
Query: 758 LPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQ--PEAPCLPP 815
P PP P+L Q L P PP + P+ +PP+ P P LPP
Sbjct: 945 PPQPTLPPQPVLPPQPTLP--PQPVLPPQPTRPPQPV--------LPPQPMLPPQPVLPP 994
Query: 816 ESPASALEPEPARPPLSALAPPHGSP 841
+ PA + PEP +P L A P +P
Sbjct: 995 Q-PALPVRPEPLQPHLPEQAAPAATP 1019
Score = 86.3 bits (212), Expect = 1e-16
Identities = 179/714 (25%), Positives = 240/714 (33%), Gaps = 157/714 (21%)
Query: 241 DLGSPPAPHASSSP---------------PSDPPLFHCSDALTPPPLPPS-----NNLPA 280
D+GSP P P +P L PP LP S ++
Sbjct: 557 DVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTF 616
Query: 281 HPGPASQPPVSSATMHLPLVLGPLGGA-----------PTVEGPGAPPFLASSLLSAAAK 329
G S S + ++LG L A P EGP P L S
Sbjct: 617 DSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPS------LG 670
Query: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQR-RPRRPPTVFRLLEGRGPQTPRRSR 388
A P P G P P + P+ P PP + G G P +
Sbjct: 671 AYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQ 730
Query: 389 P---RAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL 445
P P P+PQ + P+P P+ P L P P+ G+ L +P P
Sbjct: 731 PPPLAQPTPLPQVLA-PQPVVPLQPVPPHL--PPYLAPASQVGAPAQL-KPLQMPQAPLQ 786
Query: 446 SSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGP 505
P PI P T + +P A + P VP P SP+ L A P
Sbjct: 787 PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846
Query: 506 ACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS-PLLNHSLFGV- 563
P P +A P P PG A+P + P + PLL + GV
Sbjct: 847 LPPASPALPLQAVKLPHP-----------PGAPLAMPCRTIVPNAPATIPLLAVAPPGVA 895
Query: 564 ---LTGGGGQPPPEPLLPPPGGPGPPLAPGE-PEGPSLLVASLLPPPPSDLLPP-PSAPP 618
+ Q P +P+ P P +AP + P P V ++ PP LPP P+ PP
Sbjct: 896 ALSIHSAVAQLPGQPVYP---AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPP 952
Query: 619 SNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNS 678
P+L PT P+L P + PP +
Sbjct: 953 Q-------PVLPPQPTLPP----------------------QPVLPPQPTRPPQPVLPPQ 983
Query: 679 ALLAATLDPPSGTPPQPCVLSAP---QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQL 735
+ L P PPQP + P QP P + AT PG+ L G P
Sbjct: 984 PM----LPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT--PGSQIL------LGHP--- 1028
Query: 736 LSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLA 795
A D+++ +P++ PP +LS L LLP AP L + S LA
Sbjct: 1029 ------APYAVDVAA------QVPTVPVPPAAVLSPPLPEVLLP--AAPELLPQFPSSLA 1074
Query: 796 CLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAP-----------PHGSPDPP 844
+ S+Q P Q A LPP +P P P P +++ P S D P
Sbjct: 1075 TVSASVQSVPTQ-TATLLPPANP-----PLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128
Query: 845 --VPELLTGRG-----SGK------RGRRGGGGLRGINGEARPARGRKPGSRRE 885
+P+ G SGK G GGG L G R + SR+E
Sbjct: 1129 PGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQE 1182
Score = 55.5 bits (132), Expect = 3e-07
Identities = 78/278 (28%), Positives = 97/278 (34%), Gaps = 76/278 (27%)
Query: 187 PRLADPVPSGGSSSPRF----LPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDL 242
P P P SSP LP + AP S PS+ L S PS+
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
Query: 243 -GSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAH---PGPASQPPVSSATMHLP 298
G+PPAP A SSPP LP PA P PAS
Sbjct: 1377 PGAPPAPLAPSSPPVTA-------------LPQDGAAPATSTMPEPAS------------ 1411
Query: 299 LVLGPLGGAPTVEGPGAPPFLASSLLSA--AAKAQHPPLPPPSTLQGRRPRAQAPSASHS 356
G A GPG P L S L ++ A+ PL + G P AP A+ +
Sbjct: 1412 ------GTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAST 1465
Query: 357 SSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFS-LPEPS----QPILPS 411
R PR P PAP P P S P+P+ P+LP+
Sbjct: 1466 ----------------------RDASAPREPLP-PPAPEPSPHSGTPQPALGQPAPLLPA 1502
Query: 412 VLSLLG-----LPTP--GPSHSDGSFNLLGSDAHLPPP 442
+ + LP+P GP+ + L SD PPP
Sbjct: 1503 AVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
Score = 55.1 bits (131), Expect = 3e-07
Identities = 184/769 (23%), Positives = 239/769 (31%), Gaps = 181/769 (23%)
Query: 142 PPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSP 201
P RPP V P P+ LPP+P A P P P A P + GS
Sbjct: 970 PQPTRPPQPVLPPQPMLPPQPVLPPQP-----ALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
Query: 202 RFLPRGNAPS-----PAPPPPPAISLNAPSYNWGAALRSSLVP----------SDLGSPP 246
P A P P PPA L+ P L+P + + S P
Sbjct: 1025 LGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVP 1084
Query: 247 APHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQ--PPVSSATMHLPLVLGPL 304
A+ PP++PPL +P P P ASQ PP LP
Sbjct: 1085 TQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPP------GLPQSCESY 1138
Query: 305 GGAPTVEGPGAPP-----FLASSLLSAAAKAQHPPLPPPSTLQGR--RPRAQAPSASHSS 357
GG+ G F L AA+ H + Q R RPR + ++
Sbjct: 1139 GGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTG 1198
Query: 358 S--LRPSQRRPRRPPTVFRL-LEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414
+ F+ L+G P A V F L + + +
Sbjct: 1199 DKMVECQLETHNHKMVTFKFDLDGDAPDEI------ATYMVEHDFILQAERETFIEQMKD 1252
Query: 415 LLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPG 474
++ D + ++L D GS P P S G +G S
Sbjct: 1253 VM----------DKAEDMLSEDTDA------DRGSDPGTSPP-HLSTCGLGTGEESRQSQ 1295
Query: 475 APAPPAASKA-----------PVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523
A AP PV P ++P + P LPP A ++ P+
Sbjct: 1296 ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPL---PLSSLPPEASQDSAPYKDQ 1352
Query: 524 EQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGP 583
LS P L + L L Q PS PPG P
Sbjct: 1353 -----LSSKEQPSFLASQQL---LSQAGPSN------------------------PPGAP 1380
Query: 584 GPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAE 643
PLAP PP LP A P+ S +P A G+A
Sbjct: 1381 PAPLAPSS--------------PPVTALPQDGAAPA---TSTMPEPA--------SGTAS 1415
Query: 644 GAGGPSGEP---FSGLGDLSPLL---FPPLSAPPTLIALNSALLA--ATLDPPSGTPPQP 695
AGGP G P S L PL PL+ P ++ L A A + P +P
Sbjct: 1416 QAGGP-GTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREP 1474
Query: 696 CVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSP 755
AP+P P + + A G+P LL +GA L S L S P
Sbjct: 1475 LPPPAPEPSPHSGTPQPAL---------------GQPAPLLPAAVGAVSLA-TSQLPSPP 1518
Query: 756 GALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPP 815
QPP L S G G PP + S + L + L+ Q P
Sbjct: 1519 LGPTVPPQPPSALES--------DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV----P 1566
Query: 816 ESPASALEPEPARPPLSALAPPHGSPD-----------PPVP-ELLTGR 852
S ASA P L P G PPVP E ++GR
Sbjct: 1567 TSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGR 1615
Score = 43.9 bits (102), Expect = 8e-04
Identities = 132/558 (23%), Positives = 176/558 (31%), Gaps = 90/558 (16%)
Query: 128 EGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPP 187
E +P+ + P P S+ PP + P S SQ + AGP P
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN---P 1376
Query: 188 RLADPVPSGGSSSP-RFLPR-GNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
A P P SS P LP+ G AP+ + P PA S G L S
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPA--SGTASQAGGPGTPQGLTSELETSQ 1434
Query: 246 PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLG 305
P +P + PL TP P S + P PP + H
Sbjct: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPH--------S 1486
Query: 306 GAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRR 365
G P P L +++ + + P PP G Q PSA S P R
Sbjct: 1487 GTPQPALGQPAPLLPAAVGAVSLATSQLPSPP----LGPTVPPQPPSALESDGEGPPPRV 1542
Query: 366 PRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSH 425
T+ L E + P + A P + + + P L G
Sbjct: 1543 GFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEP----LRG-------- 1590
Query: 426 SDGSFNLLGSDAHLPP-PPTLSSGSPPQPRHPIQPSLPGTTSGSL------SSVPGAPAP 478
+ G D LPP P SG P+ ++ S T G++ SS+ +P
Sbjct: 1591 DQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSP 1650
Query: 479 -----------PAASKAPVVPS----------PVLQSPSEGLGMGAGPACPLPPLAGGEA 517
AS + VVPS P P++ G AG + PP
Sbjct: 1651 RSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPP------ 1704
Query: 518 FPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPP----PSPLLNHSLFGVLTGGG----- 568
PS + G A P LGA L +P SP F V++
Sbjct: 1705 ---PS-DMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLA 1760
Query: 569 -------GQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDL--LPPPSAPPS 619
PP L P P LA + S + + P SD P + PP
Sbjct: 1761 SPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPV 1820
Query: 620 NLLASFLPLLALGPTAGD 637
AS L G AGD
Sbjct: 1821 QKQAS---LPVSGSVAGD 1835
Score = 33.1 bits (74), Expect = 1.3
Identities = 38/129 (29%), Positives = 45/129 (34%), Gaps = 25/129 (19%)
Query: 500 GMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGALPLPLSLGQPPPSPL 555
G GAGPA P A P P++ L S P L A P G PP PL
Sbjct: 18 GRGAGPAGMAEPRAKAAR---PGPQRFLRRSVVESDQEEPPGLEAAEAP---GPQPPQPL 71
Query: 556 LNHSLFGVLT---------GGGGQPPPEPLLPPPGGPGPPLAPG------EPEGPSLLVA 600
L T G P P L+ PG PG P G + GP + A
Sbjct: 72 QRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAA 131
Query: 601 SLLPPPPSD 609
++ P D
Sbjct: 132 AVETAPAPD 140
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 98.2 bits (243), Expect = 3e-20
Identities = 231/943 (24%), Positives = 310/943 (32%), Gaps = 163/943 (17%)
Query: 159 GGPGSLPPEPPSVSQAFPT-LAGPGG---LFPP-RLADPVPSGGSSSPRFLPRGNAPSPA 213
G P EPP V P L+GP G L P + S + P LP P P
Sbjct: 194 GPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPP 253
Query: 214 PPPP--------------PAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPP 259
PPPP P L P W + P GS P P
Sbjct: 254 PPPPPPPPPPPLPGLATSPPFQLTKPGL-WSTLHGDAWGPERKGSAPPERQEQRHSLPHP 312
Query: 260 LFHCSDALTPPPLPPSNNL--PAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPP 317
+ + A T PP + L A PGP +PP + + LP P G+ E
Sbjct: 313 YPYPAPAYTAH--PPGHRLVPAAPPGPGPRPPGAESHGCLPATRPP--GSDLRESRVQRS 368
Query: 318 FLASSLLSAAAKAQHPPLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP------- 369
+ SS+ AA A P P P L G + + S+S ++ LR + P P
Sbjct: 369 RMDSSVSPAATTACVPYAPSRPPGLPG-TTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
Query: 370 PTVFRLLEGR-GPQTPRRSRP--RAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHS 426
P + GR GP +P APA P P PS P P LL P P
Sbjct: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLK 487
Query: 427 DGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPV 486
+ D + + PP+P P P G S + + P
Sbjct: 488 GPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRF--SVGTQDSHTPPT 545
Query: 487 VPSPVLQSPSEGLG----MGAGP-ACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGAL 541
P+P S + G AGP + P PP P P P S A P +
Sbjct: 546 PPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP-----SPAQNPQDPPLV 600
Query: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVAS 601
PL L+L PPS + T G + P P P + PG P GP
Sbjct: 601 PLTLALPPAPPSSCHQN------TSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQ 654
Query: 602 LLPP---------------PPSDLLPPPSAPPS-----NLLASFLPLLALGPTAGDGEGS 641
+PP PP+ L P + LA+ + +L + +
Sbjct: 655 PVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQ 714
Query: 642 AEGAGGPS---GEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATL--------DPPSG 690
E P EPF+ L P P + P + + T PP
Sbjct: 715 HEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPA 774
Query: 691 TPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLL--GDL 748
PP P + P PP+ P +SL K+ L S L G G
Sbjct: 775 LPPPPPLAKFP---PPSQPQPPPPPPPSPASLLKS---------LASVLEGQKYCYRGTG 822
Query: 749 SSLTSSPGALPSLLQPPGPLLSGQLGLQLLP-------GGGAPPPLSEASS-------PL 794
+++++ PG LP+ PGP G LP G+P P + +SS P
Sbjct: 823 AAVSTRPGPLPTTQYSPGP----PSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPW 878
Query: 795 ACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGS 854
A ++ + P P P PP PPLS PP S + E+ R
Sbjct: 879 ARERRAGEEPVPGPMTPTQPP-------------PPLS--LPPARSESEVLEEI--SRAC 921
Query: 855 GKRGRRGGGGLRGINGEARPARGRKP---GSRR--EPGRLALKWGTRGGFNGQMERSPRR 909
R G R A P +P G+ R P + + G +G +R ++
Sbjct: 922 ETLVERVG---RSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR-QK 977
Query: 910 THHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRR------------GRRRKY 957
H +H P G KVP KSRR R K
Sbjct: 978 EHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPK---EKSRRVLGNLDLQSEEIQGREKS 1034
Query: 958 NPTRNSNSSRQDIT--LEPSPTARAAVPLPPRAR-PGRPAKNK 997
P S + T PS A +A P PP A PG+ A+ +
Sbjct: 1035 RPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREE 1077
Score = 72.0 bits (175), Expect = 3e-12
Identities = 127/483 (26%), Positives = 170/483 (35%), Gaps = 76/483 (15%)
Query: 122 SHSS--PGEGASPQMFH-TVSPGPPSARPP-----CRVPPTTPLNGGPG--SLPPEPPSV 171
+HSS P GA H ++ PGP S PP R PP GP + + +
Sbjct: 442 AHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEIL 501
Query: 172 SQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGA 231
+ F GP PP L G + RF G S PP PP + ++ + N G+
Sbjct: 502 EELFFGTEGPPRPAPPPLPHREGFLGPPASRFSV-GTQDSHTPPTPPTPTTSSSNSNSGS 560
Query: 232 ALRSSLVPSDLGSP----------PAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAH 281
S P P P P + + P DPPL + AL PP PPS+
Sbjct: 561 HSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLAL--PPAPPSSCHQNT 618
Query: 282 PGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTL 341
G +P + P P V GPG PP +KA P P L
Sbjct: 619 SGSFRRPESPRPRVSFP-------KTPEV-GPGPPP-------GPLSKAPQPVPPGVGEL 663
Query: 342 QGRRPRA--QAPSASHSSSLRPSQRR--PRRPPTVFRLLE--------------GRGPQT 383
R PR P+ P++ + P + ++L+ G PQ
Sbjct: 664 PARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQP 723
Query: 384 PRRSRPRAPAPVPQPF-SLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPP 442
P + P A P P + P + P + + T + + LPPP
Sbjct: 724 PLK-EPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK----KPPPALPPP 778
Query: 443 PTLSSGSP---PQPRHPIQPSLPGTTSGSLSSVPGAP-----APPAASKAPVVPSPVLQ- 493
P L+ P PQP P PS P + SL+SV AA P P Q
Sbjct: 779 PPLAKFPPPSQPQPPPPPPPS-PASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQY 837
Query: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA----LPLPLSLGQ 549
SP G A P P A G P S + SG + A +P P++ Q
Sbjct: 838 SPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQ 897
Query: 550 PPP 552
PPP
Sbjct: 898 PPP 900
Score = 53.5 bits (127), Expect = 1e-06
Identities = 97/411 (23%), Positives = 142/411 (34%), Gaps = 79/411 (19%)
Query: 107 AVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPP 166
AVA+ T + TT + + P + P PP A+ P P P PP
Sbjct: 748 AVAVTTTTTTTTTTTATQEEEKKPPPAL----PPPPPLAKFPPPSQPQPP--------PP 795
Query: 167 EPPSVSQAFPTLAG-------------------PGGLFPPRLADPVPSGGSSSPRFLPRG 207
PPS + +LA PG L + + PSG ++ P P
Sbjct: 796 PPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP---PTS 852
Query: 208 NAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDAL 267
APS P P+ S + S + P A + P+ +
Sbjct: 853 AAPSAQGSPQPSASSS----------------SQFSTSGGPWARERRAGEEPV---PGPM 893
Query: 268 TPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAA 327
TP PP +LP P + + + ++ +G + T P P A S
Sbjct: 894 TPTQPPPPLSLP--PARSESEVLEEISRACETLVERVGRSAT--DPADPVDTAEPADSGT 949
Query: 328 AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRS 387
+ L PP+ + A S S + Q+ RR + GR PR
Sbjct: 950 ER-----LLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGR---RPREG 1001
Query: 388 RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSS 447
R +A A VP+ S VL L L + + S LG + PP +
Sbjct: 1002 RAKAKAKVPKEKSR---------RVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAP 1052
Query: 448 GSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
S P P QP+ P + + AP PP S+A ++ L+S SEG
Sbjct: 1053 PSAPAPS--AQPTPPSASVPGKKAREEAPGPPGVSRADMLK---LRSLSEG 1098
Score = 48.9 bits (115), Expect = 2e-05
Identities = 117/491 (23%), Positives = 142/491 (28%), Gaps = 118/491 (24%)
Query: 568 GGQPPPEPLLPPPGGPGPPLAPGEPEG----------------------PSL-LVASLLP 604
GG P PP P PP A P G P L L LP
Sbjct: 193 GGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLP 252
Query: 605 PPPSDLLPPPSAPPSNLLASFLPLLALGP-----TAGDGEGSAEGAGGPSGEPFSGLGDL 659
PPP PPP PP LA+ P P GD G P
Sbjct: 253 PPPPP--PPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP 310
Query: 660 SPLLFP----------------------------------PLSAPPTLIALNSALLAATL 685
P +P P + PP S + + +
Sbjct: 311 HPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
Query: 686 DPP-SGTPPQPCVLSAPQ-----PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPL 739
D S CV AP PG TSS ++++++ G + P G L
Sbjct: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
Query: 740 -------LGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPP-----PL 787
LG S +P A P L PPGP L PP P
Sbjct: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
Query: 788 SEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPE 847
A+ +L+ L E P P PP PA H P PP P
Sbjct: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
Query: 848 LLTGR-GSGKRGRRGGGGL---------RGINGEARPARGRKPGSRRE-----PGRLAL- 891
+ SG G + R I+ RP P + P LAL
Sbjct: 551 TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP---SPAQNPQDPPLVPLTLALP 607
Query: 892 -------KWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSE-DLKVPP 943
T G F + SPR + E+ G PPPGP S+ VPP
Sbjct: 608 PAPPSSCHQNTSGSF--RRPESPRPRVSFPKTPEVGPG-------PPPGPLSKAPQPVPP 658
Query: 944 GVVRKSRRGRR 954
GV RG R
Sbjct: 659 GVGELPARGPR 669
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,104,218
Number of Sequences: 37866
Number of extensions: 5968800
Number of successful extensions: 88023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 603
Number of HSP's successfully gapped in prelim test: 3026
Number of HSP's that attempted gapping in prelim test: 27081
Number of HSP's gapped (non-prelim): 31475
length of query: 1003
length of database: 18,247,518
effective HSP length: 112
effective length of query: 891
effective length of database: 14,006,526
effective search space: 12479814666
effective search space used: 12479814666
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.