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Search of human proteins with 46409340
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46409340 ankyrin repeat domain 13 family, member D [Homo
sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46409340 ankyrin repeat domain 13 family, member D [Homo sapi... 1043 0.0
gi|124517699 ankyrin repeat domain 13B [Homo sapiens] 660 0.0
gi|38683799 ankyrin repeat domain 13 [Homo sapiens] 506 e-143
gi|166795254 ankyrin repeat domain 13C [Homo sapiens] 176 4e-44
gi|194248095 epsin 1 isoform b [Homo sapiens] 42 0.001
gi|110681708 zinc finger protein 579 [Homo sapiens] 42 0.002
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 41 0.003
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 39 0.011
gi|150170653 EF-hand calcium binding domain 4A [Homo sapiens] 38 0.020
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 38 0.025
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 38 0.025
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens] 37 0.043
gi|18765741 snail 1 homolog [Homo sapiens] 37 0.057
gi|188497689 chromatin licensing and DNA replication factor 1 [H... 37 0.057
gi|156616275 DNA-directed DNA polymerase delta 1 [Homo sapiens] 37 0.057
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 36 0.097
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 36 0.097
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 35 0.22
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 34 0.28
gi|41350201 epsin 1 isoform c [Homo sapiens] 34 0.28
gi|194272148 epsin 1 isoform a [Homo sapiens] 34 0.28
gi|188219563 hypothetical protein LOC126731 [Homo sapiens] 34 0.28
gi|221139761 zinc finger protein 853 [Homo sapiens] 34 0.37
gi|229577185 epidermal growth factor receptor pathway substrate ... 34 0.37
gi|4503593 epidermal growth factor receptor pathway substrate 15... 34 0.37
gi|46559761 PDZ domain containing 4 [Homo sapiens] 34 0.37
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens] 33 0.48
gi|188536004 zinc finger protein 469 [Homo sapiens] 33 0.48
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 33 0.48
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 33 0.48
>gi|46409340 ankyrin repeat domain 13 family, member D [Homo
sapiens]
Length = 518
Score = 1043 bits (2696), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV 60
MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV
Sbjct: 1 MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV 60
Query: 61 WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE 120
WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE
Sbjct: 61 WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE 120
Query: 121 PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV 180
PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV
Sbjct: 121 PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV 180
Query: 181 YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPT 240
YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPT
Sbjct: 181 YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPT 240
Query: 241 AISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAIS 300
AISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAIS
Sbjct: 241 AISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAIS 300
Query: 301 NAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVA 360
NAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVA
Sbjct: 301 NAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVA 360
Query: 361 ASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTV 420
ASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTV
Sbjct: 361 ASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTV 420
Query: 421 WEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEE 480
WEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEE
Sbjct: 421 WEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEE 480
Query: 481 QLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH 518
QLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH
Sbjct: 481 QLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH 518
>gi|124517699 ankyrin repeat domain 13B [Homo sapiens]
Length = 626
Score = 660 bits (1704), Expect = 0.0
Identities = 337/537 (62%), Positives = 418/537 (77%), Gaps = 27/537 (5%)
Query: 1 MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV 60
+VQLVL+YRDYQR +RLAGIP LL KLR+A DFYVEMKWEFTSWVPLVSK+CPSD Y+V
Sbjct: 96 LVQLVLRYRDYQRVVKRLAGIPVLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKV 155
Query: 61 WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE 120
WK G++LRVDT+LLGF+H+TWQRG RSF+F+GQ+ A+VME+DHDR+VV+ ETL L Q+
Sbjct: 156 WKSGQNLRVDTTLLGFDHMTWQRGNRSFVFRGQDTSAVVMEIDHDRRVVYTETLALAGQD 215
Query: 121 PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV 180
E LLAA +P+EE V SRLT+P+V+T LDT+N++FERNK GI GWRSEK E V+GYEAKV
Sbjct: 216 RELLLAAAQPTEEQVLSRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNGYEAKV 275
Query: 181 YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSS-HTGAPVQQAASPTNP 239
Y A+NVEL+TRTRTEHLS+Q K + K KTP QSFLG+A+QH G + Q S NP
Sbjct: 276 YGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANP 335
Query: 240 TAISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAI 299
TAI+ EEYF+PNF L +R++GRP+E+++K Q+FKA LWL EEHPLSL +QV PIIDLMA+
Sbjct: 336 TAITAEEYFNPNFELGNRDMGRPMELTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAV 395
Query: 300 SNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSV------WVP 353
SNA FAKLRDFITLRLPPGFPVKIEIP+FH+LNARITF NL GCDEP+ SV P
Sbjct: 396 SNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSPSSETP 455
Query: 354 AP---SSAVAASGNPFP---CEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQS 407
+P SS+V++S + CE+ P +FE P GYS++G +R RD+DDDLLQFAIQQS
Sbjct: 456 SPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSMMGGQREAATRDDDDDLLQFAIQQS 515
Query: 408 LLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPP 467
LLEAG+E +QVT+WEALTN++PG P YE + Q +R+ + Q +P P S P
Sbjct: 516 LLEAGSEYDQVTIWEALTNSKPGTHP----MSYEGRRQ-DRSAPPTPQ--RQPAPPASVP 568
Query: 468 RTPPAPGP-------PSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTE 517
P+ GP S++EQLRLA+ELS++EQEER RR +QEEE+L+RIL+LSLTE
Sbjct: 569 SPRPSSGPGSGGHVFRSYDEQLRLAMELSAQEQEERRRRARQEEEELERILRLSLTE 625
>gi|38683799 ankyrin repeat domain 13 [Homo sapiens]
Length = 590
Score = 506 bits (1302), Expect = e-143
Identities = 264/518 (50%), Positives = 348/518 (67%), Gaps = 18/518 (3%)
Query: 1 MVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRV 60
MV VLQ+RDY + L G+PELL K+ +APDFYV+MKWEFTSWVPLVS++CP+DV R+
Sbjct: 89 MVYTVLQHRDYHNTSMALEGVPELLQKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRI 148
Query: 61 WKRGESLRVDTSLLGFEHVTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQE 120
WK G LRVD +LLGFE+++W RGRRSFIFKG++ A +MEV+HD +VV E L+ +
Sbjct: 149 WKSGAKLRVDITLLGFENMSWIRGRRSFIFKGEDNWAELMEVNHDDKVVTTERFDLSQEM 208
Query: 121 PETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKV 180
L M+P V RLTSP+++T LDT+N+AFER K G WGWR++K E V+GYEAKV
Sbjct: 209 ERLTLDLMKPKSREVERRLTSPVINTSLDTKNIAFERTKSGFWGWRTDKAEVVNGYEAKV 268
Query: 181 YSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPT 240
Y+ NV ++T+ RTEHL++++K R KA + P +S LG + G + A+ NPT
Sbjct: 269 YTVNNVNVITKIRTEHLTEEEKKRYKADRNPLESLLGTVEHQFGAQGDLTTECATANNPT 328
Query: 241 AISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAIS 300
AI+P+EYF+ F L+ R+IGRP E++ + Q+FKA LW+ EE PLSL +QV PIIDLMA +
Sbjct: 329 AITPDEYFNEEFDLKDRDIGRPKELTIRTQKFKAMLWMCEEFPLSLVEQVIPIIDLMART 388
Query: 301 NAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVA 360
+AHFA+LRDFI L PPGFPVKIEIPLFHVLNARITF N+ GC SV +
Sbjct: 389 SAHFARLRDFIKLEFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEESVSQNVEGTQAD 448
Query: 361 ASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTV 420
++ + EVD +VFE+P Y V RN L+DED +++QFAIQQSLLE+ E
Sbjct: 449 SASHITNFEVDQSVFEIPESYYVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQEL--- 505
Query: 421 WEALTNTRPGARPP-PQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFE 479
+ P + Q Y+ Q ERA+QESL STE P + T F+
Sbjct: 506 ------SGPASNGGISQTNTYD--AQYERAIQESLLTSTEGLCPSALSET------SRFD 551
Query: 480 EQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTE 517
L+LA+ELS++E EE E R Q+EE +LQ++LQLSLT+
Sbjct: 552 NDLQLAMELSAKELEEWELRLQEEEAELQQVLQLSLTD 589
>gi|166795254 ankyrin repeat domain 13C [Homo sapiens]
Length = 541
Score = 176 bits (447), Expect = 4e-44
Identities = 109/317 (34%), Positives = 182/317 (57%), Gaps = 18/317 (5%)
Query: 22 PELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHVTW 81
P LL L++ DFY+E+ W+F SWVPL+S++ PSD +++K+G ++R+DT+L+ F +
Sbjct: 213 PRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKC 272
Query: 82 QRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQEPETLLAAMRPSEEHVASRLTS 141
QRG SFIF G A + V + Q V+ + + E ET EE V ++S
Sbjct: 273 QRGDLSFIFNGDAAPSESFVVLDNEQKVY-QRIHHEESEMET--------EEEVDILMSS 323
Query: 142 PIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQD 201
I S L T++++F R + G W +R +K E V + A Y + L +R R EHLS++D
Sbjct: 324 DIYSATLSTKSISFTRAQTG-WLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEED 382
Query: 202 KSRSKAGKTPFQSFLGMAQQHSSHTGAPV-QQAASPTNPTAISPEEYFDPNFSLESRNIG 260
R+KA + +Q+ P+ +Q+ +P I+ EEY + ++ ++G
Sbjct: 383 ILRNKAIMESLSKGGNIMEQNFE----PIRRQSLTPPPQNTITWEEYISAE-NGKAPHLG 437
Query: 261 RPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFP 320
R + + FKAT+ +S+E PL + + + +++++A HF KLR+F+ ++LPPGFP
Sbjct: 438 RELVCKESKKTFKATIAMSQEFPLGI-ELLLNVLEVVA-PFKHFNKLREFVQMKLPPGFP 495
Query: 321 VKIEIPLFHVLNARITF 337
VK++IP+F + A +TF
Sbjct: 496 VKLDIPVFPTITATVTF 512
>gi|194248095 epsin 1 isoform b [Homo sapiens]
Length = 576
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 23/132 (17%)
Query: 392 LRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQA------TVYEEQLQ 445
LRDED +++ A E++ ++ G+ PPP+A + EE+LQ
Sbjct: 134 LRDED------RLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQ 187
Query: 446 LERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALELSSREQEERERRGQQEEE 505
L+ AL S + + + PP+ GP + QL+LAL LS E ++ ER + ++
Sbjct: 188 LQLALAMSKEEADQ----------PPSCGPED-DAQLQLALSLSREEHDKEERIRRGDDL 236
Query: 506 DLQRILQLSLTE 517
LQ ++ S E
Sbjct: 237 RLQMAIEESKRE 248
Score = 38.1 bits (87), Expect = 0.020
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 10/88 (11%)
Query: 441 EEQLQLERA--------LQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRL--ALELSS 490
E++L+ ERA L ++ S+ G G PP A S EE+L+L AL +S
Sbjct: 137 EDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSK 196
Query: 491 REQEERERRGQQEEEDLQRILQLSLTEH 518
E ++ G +++ LQ L LS EH
Sbjct: 197 EEADQPPSCGPEDDAQLQLALSLSREEH 224
Score = 33.1 bits (74), Expect = 0.63
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Query: 387 ERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQL 446
++ E +R DD LQ AI++S E G + E + A T P P P + +
Sbjct: 225 DKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPA--PAPTTDPWGGPAPM 282
Query: 447 ERALQESLQLSTEPRGPGSPPRTPPAPGP 475
A+ + S GP PP P GP
Sbjct: 283 AAAVPTAAPTSDPWGGPPVPPAADPWGGP 311
>gi|110681708 zinc finger protein 579 [Homo sapiens]
Length = 562
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 414 EAEQVTVWEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAP 473
E E+ +AL P + PPP + EQ + L + + EP PG+PP++PPAP
Sbjct: 466 ELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPLPLA-NIKEEPPSPGTPPQSPPAP 524
Query: 474 ----GPPSFEEQLRLALELSSREQEER 496
F+ Q A E+ E + +
Sbjct: 525 PVFLSASCFDSQDHSAFEMEEEEVDSK 551
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 40.8 bits (94), Expect = 0.003
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 25/123 (20%)
Query: 409 LEAGTEAEQVTVWEALTNTRP----GARPPPQATVYEEQLQLERALQESLQLSTEPRGPG 464
LE+ ++ V V E L P GA PPP A +E + GP
Sbjct: 780 LESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPL 839
Query: 465 SPPRTPPAP---------------------GPPSFEEQLRLALELSSREQEERERRGQQE 503
PP PP P GPP+ EE L + SS E+EE E ++E
Sbjct: 840 PPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEE 899
Query: 504 EED 506
EE+
Sbjct: 900 EEE 902
Score = 30.8 bits (68), Expect = 3.1
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 429 PGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALEL 488
P A PPPQ V EE L+E + ++ P PP TP EE++ E
Sbjct: 1044 PAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP--PPETPA-------EEEMETETEA 1094
Query: 489 SSREQEERE 497
+ +++E++
Sbjct: 1095 EALQEKEQD 1103
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 38.9 bits (89), Expect = 0.011
Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 15/137 (10%)
Query: 366 FPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALT 425
FPC++ T NG M ++PL +E +LL + EAG E E+
Sbjct: 446 FPCKLYHTTGNCINGDDC--MFSHDPLTEETRELLDKMLADDA-EAGAEDEKEVEELKKQ 502
Query: 426 NTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRG-------PGSPPRTPPAPGPPSF 478
P +PPP + + Q T P G P PP PP PGPP
Sbjct: 503 GINPLPKPPPGVGLLPTPPR-----PPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQM 557
Query: 479 EEQLRLALELSSREQEE 495
+ L +Q++
Sbjct: 558 PMPVHEPLSPQQLQQQD 574
Score = 29.3 bits (64), Expect = 9.1
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 464 GSPPRTPPAPGPPSF--EEQLRLALELSSREQEERERRGQQEEEDLQ 508
G P R P G P F Q L L + ++QEE ER + E Q
Sbjct: 747 GPPGRPKPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQ 793
>gi|150170653 EF-hand calcium binding domain 4A [Homo sapiens]
Length = 294
Score = 38.1 bits (87), Expect = 0.020
Identities = 44/178 (24%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
Query: 359 VAASGNPFPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEA--GTEAE 416
VA++ PC FE G V G + +E+++ ++Q + G +
Sbjct: 98 VASAQGANPCRTPEETFE-SGGLDVQGTAGSLDEEEEEEERFHTVLEQLGVAPVLGKQRA 156
Query: 417 QVTVWEALTNTRPGARPPPQATVYEEQLQLERA------LQESLQ------------LST 458
T+W L RP + + LE A L+++L+ L
Sbjct: 157 VRTLWARLQRERPELLGSFEDVLIRASACLEEAARERDGLEQALRRRESEHEREVRALYE 216
Query: 459 EPRGPGSPPRTPPAPGPPSFEEQLRLALELSSREQE-------ERERRGQQEEEDLQR 509
E R PP+ E + RL LEL SREQ+ +RERRG++ +E +R
Sbjct: 217 ETEQLREQSRRPPSQNFARGERRSRLELELQSREQDLERAGLRQRERRGRRLQEHAER 274
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 37.7 bits (86), Expect = 0.025
Identities = 39/165 (23%), Positives = 60/165 (36%), Gaps = 4/165 (2%)
Query: 344 DEPLSSVWVPAPSSAVAASGNPFPCEVDPTVFEVPNGYSVLGMERNE---PLRDEDDDLL 400
+ P S+ +P A G P P +DP V + +E E P E++
Sbjct: 1334 EPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDP 1393
Query: 401 QFAIQQSLLEAGTEAEQVTVWEALTNTRPG-ARPPPQATVYEEQLQLERALQESLQLSTE 459
+ A L+E G E EA R A P T+ EE L +
Sbjct: 1394 ERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETILEEAKVTVDDLPNRMCADVR 1453
Query: 460 PRGPGSPPRTPPAPGPPSFEEQLRLALELSSREQEERERRGQQEE 504
P PS EQ ++ EL+ + +E++ + +QEE
Sbjct: 1454 RNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEE 1498
Score = 30.0 bits (66), Expect = 5.3
Identities = 46/208 (22%), Positives = 81/208 (38%), Gaps = 26/208 (12%)
Query: 277 WLSEEHP--LSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVK--IEIPLFHVLN 332
+LSE+ P + +G ++ P + + ++ +R P + I L+ +
Sbjct: 1082 YLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFS 1141
Query: 333 ARITFSNLCGCDEPLSSVWVPAPSSAVAASGNPFPCEVDPTVFEVPNGYSVLGMERNEPL 392
+R F + + + +++ P SA +P P ++ P FE P G+E P
Sbjct: 1142 SRGRFGVVANNNRHVKDLYL-IPLSAQ----DPVPSKLLP--FEGP------GLESPRP- 1187
Query: 393 RDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQ----ATVYEEQLQLER 448
+ +L I Q + E + E T +P P ATV + + + +
Sbjct: 1188 ----NIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSK 1243
Query: 449 ALQESLQLSTEPRGPGSPPRTPPAPGPP 476
S + PGSPP PP P PP
Sbjct: 1244 YPLCSADAAVSTTPPGSPPPPPPLPEPP 1271
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 37.7 bits (86), Expect = 0.025
Identities = 27/62 (43%), Positives = 35/62 (56%), Gaps = 7/62 (11%)
Query: 441 EEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLAL--ELSSREQEERER 498
EE ++LE LQ SL EP PGSP P A PS ++++R A L + E+E RE
Sbjct: 417 EENVELELELQRSL----EPP-PGSPGEAPLAGAAPSLQDEVREAEAGRLRTLERENREL 471
Query: 499 RG 500
RG
Sbjct: 472 RG 473
>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
Length = 636
Score = 37.0 bits (84), Expect = 0.043
Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 16/146 (10%)
Query: 384 LGMERNEPLRDEDDDLLQFAIQQSLLEAGTE---AEQVTVWEALTNTRPGARPPPQATVY 440
L ER + RD D LL + + E E AE + + + + P + Y
Sbjct: 352 LEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQLSPLTRQREY 411
Query: 441 EEQ--LQLERALQESLQLSTEPRGPGSPPRTPPAPGP-----------PSFEEQLRLALE 487
+E+ +L +AL+E+L + T P P + +P G ++Q+++ E
Sbjct: 412 QEKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEE 471
Query: 488 LSSREQEERERRGQQEEEDLQRILQL 513
RE+ +RER +++EE +++ +L
Sbjct: 472 DFQRERSDRERMNEEKEELKKQVEKL 497
>gi|18765741 snail 1 homolog [Homo sapiens]
Length = 264
Score = 36.6 bits (83), Expect = 0.057
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Query: 413 TEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPA 472
T + + +W+++ P A+P A++ +LQ + E LS E G GS P +PP+
Sbjct: 53 TASLPMLIWDSVL--APQAQPIAWASL---RLQESPRVAELTSLSDEDSGKGSQPPSPPS 107
Query: 473 PGPPSFEEQLRLALE 487
P P SF +LE
Sbjct: 108 PAPSSFSSTSVSSLE 122
>gi|188497689 chromatin licensing and DNA replication factor 1 [Homo
sapiens]
Length = 546
Score = 36.6 bits (83), Expect = 0.057
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 31/129 (24%)
Query: 416 EQVTVWEALTNT------RPGARPPPQAT----VYEEQL---------QLERALQESLQL 456
+Q+T W N P A P P AT +E L ++E+AL +
Sbjct: 326 DQLTRWHPRFNVDEVPDIEPAALPQPPATEKLTTAQEVLARARNLISPRMEKALSQLALR 385
Query: 457 STEPRGPGS--------PPRTPPAPGPPSFEEQLRLALELSSREQEERE----RRGQQEE 504
S P PGS PP TPPA P + + + LE ++ +++ R ++E
Sbjct: 386 SAAPSSPGSPRPALPATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQE 445
Query: 505 EDLQRILQL 513
+ LQR+ +L
Sbjct: 446 QRLQRLERL 454
>gi|156616275 DNA-directed DNA polymerase delta 1 [Homo sapiens]
Length = 1107
Score = 36.6 bits (83), Expect = 0.057
Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 13/59 (22%)
Query: 462 GPGSPPRTP--------PAPGPPSFEEQLRLALELSSREQEERERRGQQEEEDLQRILQ 512
GPG PP+ AP P FEE L L E E R +QEEE+LQ +L+
Sbjct: 10 GPGVPPKRARGGLWDDDDAPRPSQFEEDLALM-----EEMEAEHRLQEQEEEELQSVLE 63
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 35.8 bits (81), Expect = 0.097
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
Query: 404 IQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGP 463
+QQ+L EAEQ Q +E ++++ LQE+LQL + R
Sbjct: 392 LQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRD 451
Query: 464 GSPPRTPPAPGPPSFEEQLRLALELSSREQEERERRGQQEEEDLQR 509
R EE+L+ ++L EQE R QQE+E+LQ+
Sbjct: 452 EESVRIAQTRLLEEEEEKLKQLMQL-KEEQERYIERAQQEKEELQQ 496
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 35.8 bits (81), Expect = 0.097
Identities = 39/117 (33%), Positives = 48/117 (41%), Gaps = 15/117 (12%)
Query: 406 QSLLEAGTEAEQVTVWEALTNTRPGARP-PPQATVYEEQLQLERALQESLQLSTEPRGPG 464
QS A E E + P P PPQ +EQ E ++ T P P
Sbjct: 528 QSKRRASNEKESAAPASPAPSPAPSPTPAPPQ----KEQPPAETPTDAAVL--TSPPAP- 580
Query: 465 SPPRTP--PAPGPPSFEEQLRLALE-----LSSREQEERERRGQQEEEDLQRILQLS 514
+PP TP P G EE RL E RE+EE+ERR Q E + R QL+
Sbjct: 581 APPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLA 637
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 34.7 bits (78), Expect = 0.22
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 5/70 (7%)
Query: 433 PPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALELSSRE 492
PPP+A E ++ AL+E+ ST P+G G PP PP P S + + S+++
Sbjct: 245 PPPKAAFKEPKM----ALKETKLESTSPKG-GPPPPPPPPPRASSKRPATADSPKPSAKK 299
Query: 493 QEERERRGQQ 502
Q++ +G +
Sbjct: 300 QKKSSSKGSR 309
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 34.3 bits (77), Expect = 0.28
Identities = 37/167 (22%), Positives = 64/167 (38%), Gaps = 36/167 (21%)
Query: 382 SVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVT----VWEALTN----------- 426
SV ++ + L + D L A Q+LL T+ + + VW A+ +
Sbjct: 230 SVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDL 289
Query: 427 --------TRPGARPPP---QATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAPGP 475
T P PP T EE+ + E + + E PP +PP P
Sbjct: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPAS 349
Query: 476 PS-------FEEQLRLALELSSREQ---EERERRGQQEEEDLQRILQ 512
P+ ++EQ + ++ + + EE ER + EE ++ + Q
Sbjct: 350 PAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQ 396
>gi|41350201 epsin 1 isoform c [Homo sapiens]
Length = 550
Score = 34.3 bits (77), Expect = 0.28
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 18/89 (20%)
Query: 441 EEQLQLERA--------LQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALELS--- 489
E++L+ ERA L ++ S+ G G PP A S EE+L+L L L+
Sbjct: 137 EDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSK 196
Query: 490 -SREQEERERRGQQEEEDLQRILQLSLTE 517
+QEER RRG +DL+ LQ+++ E
Sbjct: 197 EEADQEERIRRG----DDLR--LQMAIEE 219
Score = 32.7 bits (73), Expect = 0.82
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Query: 387 ERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQL 446
++ E +R DD LQ AI++S E G + E + A T P P P + +
Sbjct: 200 DQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPA--PAPTTDPWGGPAPM 257
Query: 447 ERALQESLQLSTEPRGPGSPPRTPPAPGP 475
A+ + S GP PP P GP
Sbjct: 258 AAAVPTAAPTSDPWGGPPVPPAADPWGGP 286
>gi|194272148 epsin 1 isoform a [Homo sapiens]
Length = 662
Score = 34.3 bits (77), Expect = 0.28
Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 18/89 (20%)
Query: 441 EEQLQLERA--------LQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLALELS--- 489
E++L+ ERA L ++ S+ G G PP A S EE+L+L L L+
Sbjct: 248 EDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSK 307
Query: 490 -SREQEERERRGQQEEEDLQRILQLSLTE 517
+QEER RRG +DL+ LQ+++ E
Sbjct: 308 EEADQEERIRRG----DDLR--LQMAIEE 330
Score = 32.7 bits (73), Expect = 0.82
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Query: 387 ERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQL 446
++ E +R DD LQ AI++S E G + E + A T P P P + +
Sbjct: 311 DQEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPA--PAPTTDPWGGPAPM 368
Query: 447 ERALQESLQLSTEPRGPGSPPRTPPAPGP 475
A+ + S GP PP P GP
Sbjct: 369 AAAVPTAAPTSDPWGGPPVPPAADPWGGP 397
>gi|188219563 hypothetical protein LOC126731 [Homo sapiens]
Length = 270
Score = 34.3 bits (77), Expect = 0.28
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 11/54 (20%)
Query: 457 STEPRGPGSP-PR-TPPAPGPPSFEEQLRLALELSSREQEERERRGQQEEEDLQ 508
S+E G G P PR PP+P PP +E +++E+ ER RG EE+D +
Sbjct: 63 SSESSGAGGPAPRCAPPSPPPP---------VEPATQEEAERRARGAPEEQDAE 107
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 33.9 bits (76), Expect = 0.37
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 19/142 (13%)
Query: 387 ERNEPLRDEDDDLL---QFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQ 443
++ E L+ + LL Q +QQ LL+ +Q + + L + +EQ
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQLLQQ----QQAQLQQQLLEQQQAQLQQQLLLQQQEQ 285
Query: 444 LQLERALQESLQLSTEPRGPGSPPRTPPAPGPPSFEEQLRLAL---ELSSREQEERERRG 500
LQ Q+ QL + + + P P P EE++ L L +L S ++ E++R+
Sbjct: 286 LQQ----QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQE 341
Query: 501 QQEEEDL-----QRILQLSLTE 517
+ +++L QR LQL L E
Sbjct: 342 LERQQELERQQEQRQLQLKLQE 363
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 33.9 bits (76), Expect = 0.37
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 476 PSFEEQLRLALELSSREQEER-ERRGQQEEEDLQRILQLSLTE 517
PS E+ + A S RE+E+R R QQE+EDL+ + LS +E
Sbjct: 536 PSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSE 578
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 33.9 bits (76), Expect = 0.37
Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 476 PSFEEQLRLALELSSREQEER-ERRGQQEEEDLQRILQLSLTE 517
PS E+ + A S RE+E+R R QQE+EDL+ + LS +E
Sbjct: 850 PSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKSE 892
>gi|46559761 PDZ domain containing 4 [Homo sapiens]
Length = 769
Score = 33.9 bits (76), Expect = 0.37
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 426 NTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGP--GSPPRTPPAPGPPSFEEQLR 483
NT R P + L RA+ + L+ P GP +P + P PG P+ L
Sbjct: 472 NTGESCRSTPLLVEPLPESPLRRAMAGNSNLNRTPPGPAVATPAKAAPPPGSPAKFRSLS 531
Query: 484 LALELSSREQ-EERERRGQQEEEDLQRI 510
E R+ EER RR + L+R+
Sbjct: 532 RDPEAGRRQHAEERGRRNPKTGLTLERV 559
>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
Length = 381
Score = 33.5 bits (75), Expect = 0.48
Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 9/79 (11%)
Query: 423 ALTNTRPGARPPPQATVYEEQLQLERALQESLQLSTEPRGPGSPPRTPPAP--GPPSFEE 480
A T TRP P + + + R P P +PPR PPA PP+
Sbjct: 279 AATTTRPQTTPAAASPDLPQPAERSRG-------EPRPAEPRAPPRPPPAARRPPPATAP 331
Query: 481 QLRLALELSSREQEERERR 499
R A +RE+E R RR
Sbjct: 332 SPRRAGSPPTREEEPRPRR 350
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 33.5 bits (75), Expect = 0.48
Identities = 23/51 (45%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 428 RPGARPPPQATVYEEQLQLERALQE--SLQLSTEPRGPGSPPRTPPAPGPP 476
RPG P +A E+L R QE S ST P + PR PPAPGPP
Sbjct: 163 RPGL-PRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPR-PPAPGPP 211
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 33.5 bits (75), Expect = 0.48
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 424 LTNTRPGARPPPQATVYEEQLQLERALQ---ESLQLSTEPRGPGSPPRTPPAPGPPSFEE 480
+++T R P + + +EQ QLE+ L E + RG + A +E
Sbjct: 320 ISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKE 379
Query: 481 QLRLA-LELSSREQEERERRGQQEEEDLQRILQL 513
Q RLA LE + +E++ERER+ Q+ + L+ QL
Sbjct: 380 QERLAQLERAEQERKERERQEQERKRQLELEKQL 413
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 33.5 bits (75), Expect = 0.48
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 424 LTNTRPGARPPPQATVYEEQLQLERALQ---ESLQLSTEPRGPGSPPRTPPAPGPPSFEE 480
+++T R P + + +EQ QLE+ L E + RG + A +E
Sbjct: 320 ISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKE 379
Query: 481 QLRLA-LELSSREQEERERRGQQEEEDLQRILQL 513
Q RLA LE + +E++ERER+ Q+ + L+ QL
Sbjct: 380 QERLAQLERAEQERKERERQEQERKRQLELEKQL 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,050,703
Number of Sequences: 37866
Number of extensions: 1137204
Number of successful extensions: 11372
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 10310
Number of HSP's gapped (non-prelim): 1106
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.