Guide to the Human Genome
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Name: NPHP1 Sequence: fasta or formatted (733aa) NCBI GI: 46397398
Description:

nephrocystin 1 isoform 1

Referenced in:

Kidney
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [732aa] nephrocystin 1 isoform 2
alt prot [677aa] nephrocystin 1 isoform 3
alt prot [614aa] nephrocystin 1 isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         40           1
 C cysteine            1.4         10           1
 D aspartate           5.0         37           1
 E glutamate          10.4         76           6
 F phenylalanine       3.5         26           1
 G glycine             5.6         41           2
 H histidine           1.8         13           1
 I isoleucine          4.9         36           1
 K lysine              5.2         38           2
 L leucine            11.7         86           2
 M methionine          2.2         16           1
 N asparagine          3.7         27           1
 P proline             4.8         35           2
 Q glutamine           5.6         41           2
 R arginine            6.4         47           3
 S serine              7.9         58           2
 T threonine           5.5         40           2
 V valine              5.3         39           1
 W tryptophan          1.8         13           2
 Y tyrosine            1.9         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nephrocystin 1 isoform 1 
NPHP1                 0.995   nephrocystin 1 isoform 2 
NPHP1                 0.867   nephrocystin 1 isoform 3 
NPHP1                 0.735   nephrocystin 1 isoform 4 
CDC2L1                0.027   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.027   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.027   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.027   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L2                0.026   cell division cycle 2-like 2 isoform 4 
CDC2L2                0.026   cell division cycle 2-like 2 isoform 1 
CDC2L1                0.024   cell division cycle 2-like 1 (PITSLRE proteins) isof...
ITSN2                 0.022   intersectin 2 isoform 3 
ITSN2                 0.022   intersectin 2 isoform 1 
ITSN2                 0.022   intersectin 2 isoform 2 
TRIP10                0.022   thyroid hormone receptor interactor 10 
CDC2L1                0.022   cell division cycle 2-like 1 (PITSLRE proteins) isof...
RPGR                  0.021   retinitis pigmentosa GTPase regulator isoform C [Hom...
CRK                   0.021   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CRK                   0.020   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
ABI2                  0.020   abl interactor 2 
EIF5B                 0.020   eukaryotic translation initiation factor 5B 
CRKL                  0.019   v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...
CENPB                 0.019   centromere protein B 
MYT1                  0.019   myelin transcription factor 1 
SH3PXD2A              0.019   SH3 multiple domains 1 
FNBP1L                0.018   formin binding protein 1-like isoform 1 
FNBP1L                0.018   formin binding protein 1-like isoform 2 
HUWE1                 0.018   HECT, UBA and WWE domain containing 1 
TTBK1                 0.018   tau tubulin kinase 1 
SRGAP2                0.018   SLIT-ROBO Rho GTPase activating protein 2 isoform a...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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