Guide to the Human Genome
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Name: NPHP1 Sequence: fasta or formatted (677aa) NCBI GI: 189491776
Description:

nephrocystin 1 isoform 3

Referenced in:

Kidney
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [732aa] nephrocystin 1 isoform 2
alt prot [614aa] nephrocystin 1 isoform 4
alt prot [733aa] nephrocystin 1 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         38           1
 C cysteine            1.2          8           1
 D aspartate           5.3         36           1
 E glutamate          10.8         73           6
 F phenylalanine       3.2         22           1
 G glycine             5.5         37           2
 H histidine           1.8         12           1
 I isoleucine          4.9         33           1
 K lysine              5.5         37           2
 L leucine            12.0         81           2
 M methionine          2.1         14           1
 N asparagine          3.4         23           1
 P proline             5.0         34           2
 Q glutamine           5.8         39           2
 R arginine            6.2         42           3
 S serine              8.0         54           2
 T threonine           5.5         37           2
 V valine              4.7         32           1
 W tryptophan          1.8         12           2
 Y tyrosine            1.9         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nephrocystin 1 isoform 3 
NPHP1                 0.940   nephrocystin 1 isoform 1 
NPHP1                 0.927   nephrocystin 1 isoform 2 
NPHP1                 0.865   nephrocystin 1 isoform 4 
CDC2L1                0.028   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.028   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.028   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.028   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L2                0.026   cell division cycle 2-like 2 isoform 4 
CDC2L2                0.026   cell division cycle 2-like 2 isoform 1 
CDC2L1                0.025   cell division cycle 2-like 1 (PITSLRE proteins) isof...
ITSN2                 0.024   intersectin 2 isoform 3 
ITSN2                 0.024   intersectin 2 isoform 1 
ITSN2                 0.024   intersectin 2 isoform 2 
TRIP10                0.023   thyroid hormone receptor interactor 10 
RPGR                  0.023   retinitis pigmentosa GTPase regulator isoform C [Hom...
CRK                   0.023   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CDC2L1                0.022   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CRK                   0.022   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
ABI2                  0.022   abl interactor 2 
CRKL                  0.021   v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...
CENPB                 0.021   centromere protein B 
MYT1                  0.021   myelin transcription factor 1 
SH3PXD2A              0.020   SH3 multiple domains 1 
FNBP1L                0.020   formin binding protein 1-like isoform 1 
FNBP1L                0.020   formin binding protein 1-like isoform 2 
HUWE1                 0.020   HECT, UBA and WWE domain containing 1 
TTBK1                 0.020   tau tubulin kinase 1 
PSTPIP1               0.019   proline-serine-threonine phosphatase interacting pro...
LOC645202             0.019   PREDICTED: hypothetical protein LOC645202 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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