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Search of human proteins with 46397310
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46397310 polyamine oxidase isoform 4 [Homo sapiens]
(486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46397310 polyamine oxidase isoform 4 [Homo sapiens] 989 0.0
gi|23097272 polyamine oxidase isoform 1 [Homo sapiens] 842 0.0
gi|46397308 polyamine oxidase isoform 2 [Homo sapiens] 593 e-169
gi|28559074 spermine oxidase isoform 1 [Homo sapiens] 251 8e-67
gi|28559080 spermine oxidase isoform 4 [Homo sapiens] 228 9e-60
gi|28559076 spermine oxidase isoform 2 [Homo sapiens] 228 9e-60
gi|28559078 spermine oxidase isoform 3 [Homo sapiens] 73 5e-13
gi|38202207 monoamine oxidase B [Homo sapiens] 60 4e-09
gi|58761544 amine oxidase (flavin containing) domain 2 isoform a... 54 2e-07
gi|58761546 amine oxidase (flavin containing) domain 2 isoform b... 54 2e-07
gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sa... 52 9e-07
gi|4557735 monoamine oxidase A [Homo sapiens] 41 0.002
gi|170650615 protoporphyrinogen oxidase [Homo sapiens] 40 0.004
gi|4506001 protoporphyrinogen oxidase [Homo sapiens] 40 0.004
gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo sa... 40 0.005
gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens] 40 0.005
gi|153792768 claudin 6 [Homo sapiens] 32 1.7
gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain... 31 2.9
gi|11560152 zinc finger protein 335 [Homo sapiens] 31 2.9
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 30 3.8
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 30 3.8
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 30 3.8
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 30 3.8
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 30 4.9
gi|11225256 uncoupling protein 1 [Homo sapiens] 30 6.4
gi|119703746 electron-transferring-flavoprotein dehydrogenase pr... 30 6.4
gi|4504383 HGF activator preproprotein [Homo sapiens] 30 6.4
gi|118600963 Nik related kinase [Homo sapiens] 30 6.4
gi|239753767 PREDICTED: hypothetical protein [Homo sapiens] 29 8.4
gi|239748329 PREDICTED: hypothetical protein [Homo sapiens] 29 8.4
>gi|46397310 polyamine oxidase isoform 4 [Homo sapiens]
Length = 486
Score = 989 bits (2558), Expect = 0.0
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF
Sbjct: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
Query: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA
Sbjct: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
Query: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK
Sbjct: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
Query: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
Sbjct: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
Query: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF 300
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF
Sbjct: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF 300
Query: 301 DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW 360
DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW
Sbjct: 301 DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW 360
Query: 361 FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGS 420
FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGS
Sbjct: 361 FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGS 420
Query: 421 HTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLL 480
HTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLL
Sbjct: 421 HTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLL 480
Query: 481 TDFSLA 486
TDFSLA
Sbjct: 481 TDFSLA 486
>gi|23097272 polyamine oxidase isoform 1 [Homo sapiens]
Length = 511
Score = 842 bits (2176), Expect = 0.0
Identities = 428/468 (91%), Positives = 430/468 (91%), Gaps = 9/468 (1%)
Query: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF
Sbjct: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
Query: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA
Sbjct: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
Query: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK
Sbjct: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
Query: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
Sbjct: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
Query: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF 300
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF
Sbjct: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF 300
Query: 301 DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW 360
DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW
Sbjct: 301 DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW 360
Query: 361 FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGS 420
FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVT +
Sbjct: 361 FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPK 420
Query: 421 HTSHVLLHDA---RGS----AVGMEGGRPP--PQSVGPAGAAAQAQAL 459
H A RGS AVG GG Q + GA AQ Q L
Sbjct: 421 SVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQIL 468
>gi|46397308 polyamine oxidase isoform 2 [Homo sapiens]
Length = 325
Score = 593 bits (1529), Expect = e-169
Identities = 295/305 (96%), Positives = 295/305 (96%), Gaps = 5/305 (1%)
Query: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF
Sbjct: 1 MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF 60
Query: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA
Sbjct: 61 GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA 120
Query: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK
Sbjct: 121 SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK 180
Query: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
Sbjct: 181 LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT 240
Query: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF 300
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLG L TF
Sbjct: 241 VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLG-----LSTFS 295
Query: 301 DPPLP 305
LP
Sbjct: 296 VGSLP 300
>gi|28559074 spermine oxidase isoform 1 [Homo sapiens]
Length = 555
Score = 251 bits (642), Expect = 8e-67
Identities = 165/463 (35%), Positives = 235/463 (50%), Gaps = 64/463 (13%)
Query: 2 ESTGSVGEAP--------GGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR 53
ES+G + P G PRV+V+G G+AGL AA+ L F + VLEA++ GGR
Sbjct: 5 ESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALL-EQGFTDVTVLEASSHIGGR 63
Query: 54 IRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSV 113
++S + E+GA WIHG S GNP++ LA GLL E + + G + L S
Sbjct: 64 VQSVKLGHATFELGATWIHG-SHGNPIYHLAEANGLLEETTDGERSV-----GRISLYSK 117
Query: 114 S-----YASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVP-----SVGEYLKKEI 163
+ + G + +V E + L+ + + T+EF + PV SVG + ++E+
Sbjct: 118 NGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRH-DKPVNAESQNSVGVFTREEV 176
Query: 164 GQHVAGWTEDEE-TRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFS 222
+ +D E T++LKLA++ + +E C S +HSMD V+L+ FGE+T +PG
Sbjct: 177 RNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIP 236
Query: 223 KGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFP-------------------- 262
G+ + + +P + KPV+ IHW+ + P
Sbjct: 237 SGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQG 296
Query: 263 -----------GETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEA 311
E + V VECED + PA HVIVTV LG L+ +FF P LP EK A
Sbjct: 297 GEEPRGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAA 356
Query: 312 IRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAA--PELQDAWFRKLIGFVV 369
I ++G GT +KIFLEFEEPFW P+C +Q VWED + PEL W+RK+ GF V
Sbjct: 357 IHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYPPEL---WYRKICGFDV 413
Query: 370 L-PAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVT 411
L P HVL G+I G E+ ME DE V T++LR+ T
Sbjct: 414 LYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFT 456
>gi|28559080 spermine oxidase isoform 4 [Homo sapiens]
Length = 532
Score = 228 bits (581), Expect = 9e-60
Identities = 152/432 (35%), Positives = 220/432 (50%), Gaps = 55/432 (12%)
Query: 2 ESTGSVGEAP--------GGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR 53
ES+G + P G PRV+V+G G+AGL AA+ L F + VLEA++ GGR
Sbjct: 5 ESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALL-EQGFTDVTVLEASSHIGGR 63
Query: 54 IRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSV 113
++S + E+GA WIHG S GNP++ LA GLL E + + G + L S
Sbjct: 64 VQSVKLGHATFELGATWIHG-SHGNPIYHLAEANGLLEETTDGERSV-----GRISLYSK 117
Query: 114 S-----YASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVP-----SVGEYLKKEI 163
+ + G + +V E + L+ + + T+EF + PV SVG + ++E+
Sbjct: 118 NGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRH-DKPVNAESQNSVGVFTREEV 176
Query: 164 GQHVAGWTEDEE-TRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFS 222
+ +D E T++LKLA++ + +E C S +HSMD V+L+ FGE+T +PG
Sbjct: 177 RNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIP 236
Query: 223 KGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHH 282
G+ + + +P + KPV+ IHW+ + P E E
Sbjct: 237 SGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGP--------EIE--------- 279
Query: 283 VIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLV 342
P G L+ +FF P LP EK AI ++G GT +KIFLEFEEPFW P+C +Q V
Sbjct: 280 -----PRGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFV 334
Query: 343 WEDTSPLEDAA--PELQDAWFRKLIGFVVL-PAFASVHVLCGFIAGLESEFMETLSDEEV 399
WED + PEL W+RK+ GF VL P HVL G+I G E+ ME DE V
Sbjct: 335 WEDEAESHTLTYPPEL---WYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAV 391
Query: 400 LLCLTQVLRRVT 411
T++LR+ T
Sbjct: 392 AEICTEMLRQFT 403
>gi|28559076 spermine oxidase isoform 2 [Homo sapiens]
Length = 502
Score = 228 bits (581), Expect = 9e-60
Identities = 152/432 (35%), Positives = 220/432 (50%), Gaps = 55/432 (12%)
Query: 2 ESTGSVGEAP--------GGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR 53
ES+G + P G PRV+V+G G+AGL AA+ L F + VLEA++ GGR
Sbjct: 5 ESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALL-EQGFTDVTVLEASSHIGGR 63
Query: 54 IRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSV 113
++S + E+GA WIHG S GNP++ LA GLL E + + G + L S
Sbjct: 64 VQSVKLGHATFELGATWIHG-SHGNPIYHLAEANGLLEETTDGERSV-----GRISLYSK 117
Query: 114 S-----YASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVP-----SVGEYLKKEI 163
+ + G + +V E + L+ + + T+EF + PV SVG + ++E+
Sbjct: 118 NGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRH-DKPVNAESQNSVGVFTREEV 176
Query: 164 GQHVAGWTEDEE-TRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFS 222
+ +D E T++LKLA++ + +E C S +HSMD V+L+ FGE+T +PG
Sbjct: 177 RNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIP 236
Query: 223 KGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHH 282
G+ + + +P + KPV+ IHW+ + P E E
Sbjct: 237 SGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGP--------EIE--------- 279
Query: 283 VIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLV 342
P G L+ +FF P LP EK AI ++G GT +KIFLEFEEPFW P+C +Q V
Sbjct: 280 -----PRGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFV 334
Query: 343 WEDTSPLEDAA--PELQDAWFRKLIGFVVL-PAFASVHVLCGFIAGLESEFMETLSDEEV 399
WED + PEL W+RK+ GF VL P HVL G+I G E+ ME DE V
Sbjct: 335 WEDEAESHTLTYPPEL---WYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAV 391
Query: 400 LLCLTQVLRRVT 411
T++LR+ T
Sbjct: 392 AEICTEMLRQFT 403
>gi|28559078 spermine oxidase isoform 3 [Homo sapiens]
Length = 190
Score = 73.2 bits (178), Expect = 5e-13
Identities = 43/99 (43%), Positives = 58/99 (58%), Gaps = 10/99 (10%)
Query: 2 ESTGSVGEAP--------GGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR 53
ES+G + P G PRV+V+G G+AGL AA+ L F + VLEA++ GGR
Sbjct: 5 ESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALL-EQGFTDVTVLEASSHIGGR 63
Query: 54 IRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGE 92
++S + E+GA WIHG S GNP++ LA GLL E
Sbjct: 64 VQSVKLGHATFELGATWIHG-SHGNPIYHLAEANGLLEE 101
>gi|38202207 monoamine oxidase B [Homo sapiens]
Length = 520
Score = 60.1 bits (144), Expect = 4e-09
Identities = 99/377 (26%), Positives = 164/377 (43%), Gaps = 61/377 (16%)
Query: 16 VLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR---IRSERCFGGVVEVGAHWIH 72
V+VVGGGI+G+ AA+ L H + ++ VLEA R GGR +R+++ V++G ++
Sbjct: 7 VVVVGGGISGMAAAKLL--HDSGLNVVVLEARDRVGGRTYTLRNQKV--KYVDLGGSYV- 61
Query: 73 GPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMAT 132
GP++ N + +LA E GL E + N++ HV S + V +
Sbjct: 62 GPTQ-NRILRLAKELGL----ETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHN 116
Query: 133 LFYGLIDQT-REFLHAAETPVPSVGEY---LKKEIGQHVAGWTEDEETRKLKLAVLNSFF 188
F+ +D RE A P E+ KE+ + WTE + +LA L F
Sbjct: 117 NFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLC-WTESAK----QLATL--FV 169
Query: 189 NLECCVSGTHSMDLVALAPFGEY---------TVLPGLDCTFSKGYQGLTNCMMAALPED 239
NL C + TH + + + + T G + F G ++ +M L D
Sbjct: 170 NL-CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLL-GD 227
Query: 240 TVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVP--LGFLREHLD 297
V E+PV I V VE + + + A +VI +P LG +
Sbjct: 228 RVKLERPVIYIDQTRE-----------NVLVETLNHEMYEAKYVISAIPPTLG-----MK 271
Query: 298 TFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPD--CQLIQLVWEDTS---PLEDA 352
F+PPLP + + I ++ G+ K + ++EPFW C + + E+ L+D
Sbjct: 272 IHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDT 331
Query: 353 APELQDAWFRKLIGFVV 369
PE + ++GF++
Sbjct: 332 KPE---GNYAAIMGFIL 345
>gi|58761544 amine oxidase (flavin containing) domain 2 isoform a
[Homo sapiens]
Length = 876
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 283 VIVTVPLGFLREHLDTF-FDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQL 341
V+ T+PLG L++ F PPLP K A++++GFG NK+ L F+ FW+P L
Sbjct: 645 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGH 704
Query: 342 VWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVL 400
V T+ + EL W +L +AG + ME +SD+ ++
Sbjct: 705 VGSTTA----SRGELFLFW-----------NLYKAPILLALVAGEAAGIMENISDDVIV 748
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 15 RVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGP 74
+V+++G G++GL AA++L S + +LEA R GGR+ + R V ++GA + G
Sbjct: 300 KVIIIGSGVSGLAAARQL--QSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGL 357
Query: 75 SRGNPVFQLAAEYGLLGEKELSQENQLVETGG 106
GNP+ ++ + + K + Q+ L E G
Sbjct: 358 G-GNPMAVVSKQVNMELAK-IKQKCPLYEANG 387
>gi|58761546 amine oxidase (flavin containing) domain 2 isoform b
[Homo sapiens]
Length = 852
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 16/119 (13%)
Query: 283 VIVTVPLGFLREHLDTF-FDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQL 341
V+ T+PLG L++ F PPLP K A++++GFG NK+ L F+ FW+P L
Sbjct: 621 VLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGH 680
Query: 342 VWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVL 400
V T+ + EL W +L +AG + ME +SD+ ++
Sbjct: 681 VGSTTA----SRGELFLFW-----------NLYKAPILLALVAGEAAGIMENISDDVIV 724
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 15 RVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGP 74
+V+++G G++GL AA++L S + +LEA R GGR+ + R V ++GA + G
Sbjct: 280 KVIIIGSGVSGLAAARQL--QSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGL 337
Query: 75 SRGNPVFQLAAEYGLLGEKELSQENQLVETGG 106
GNP+ ++ + + K + Q+ L E G
Sbjct: 338 G-GNPMAVVSKQVNMELAK-IKQKCPLYEANG 367
>gi|116256451 amine oxidase (flavin containing) domain 1 [Homo
sapiens]
Length = 590
Score = 52.4 bits (124), Expect = 9e-07
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 24/130 (18%)
Query: 209 GEYTVL-PGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFP 267
G++T+L PG K +GL + + PV+ I ++G
Sbjct: 338 GDHTLLTPGYSVIIEKLAEGLD-----------IQLKSPVQCIDYSGD-----------E 375
Query: 268 VSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEF 327
V V DG + A V+VTVPL L++ F +PPL +K +AI +G G KI L+F
Sbjct: 376 VQVTTTDGTGYSAQKVLVTVPLALLQKGAIQF-NPPLSEKKMKAINSLGAGIIEKIALQF 434
Query: 328 EEPFWEPDCQ 337
FW+ Q
Sbjct: 435 PYRFWDSKVQ 444
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/66 (42%), Positives = 40/66 (60%), Gaps = 4/66 (6%)
Query: 16 VLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGV-VEVGAHWIHGP 74
V+++G G AGL AA++L H+ + VLEA R GGR+ ++ F GV V GA ++G
Sbjct: 253 VIIIGAGPAGLAAARQL--HNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG- 309
Query: 75 SRGNPV 80
NPV
Sbjct: 310 CINNPV 315
>gi|4557735 monoamine oxidase A [Homo sapiens]
Length = 527
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 9/77 (11%)
Query: 16 VLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGR---IRSERCFGGVVEVGAHWIH 72
V+V+GGGI+GL AA+ L + + VLEA R GGR IR+E V+VG ++
Sbjct: 16 VVVIGGGISGLSAAKLLTEYGV--SVLVLEARDRVGGRTYTIRNEHV--DYVDVGGAYV- 70
Query: 73 GPSRGNPVFQLAAEYGL 89
GP++ N + +L+ E G+
Sbjct: 71 GPTQ-NRILRLSKELGI 86
Score = 33.5 bits (75), Expect = 0.45
Identities = 25/110 (22%), Positives = 52/110 (47%), Gaps = 17/110 (15%)
Query: 268 VSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEF 327
+ +E + + + +VI +P + F P LPAE+ + I+++ G K + +
Sbjct: 254 IIIETLNHEHYECKYVINAIPPTLTAK---IHFRPELPAERNQLIQRLPMGAVIKCMMYY 310
Query: 328 EEPFWEP----DCQLIQLVWEDTSP----LEDAAPELQDAWFRKLIGFVV 369
+E FW+ C +I+ ++ +P L+D P D ++GF++
Sbjct: 311 KEAFWKKKDYCGCMIIE---DEDAPISITLDDTKP---DGSLPAIMGFIL 354
>gi|170650615 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 13 GPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSER-CFGGVVEVGAHWI 71
G V+V+GGGI+GL A+ L P + ++E++ R GG IRS R G + E+G I
Sbjct: 2 GRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPRGI 61
Query: 72 H-GPSRGNPVFQLAAEYGLLGE 92
+ G L +E GL E
Sbjct: 62 RPAGALGARTLLLVSELGLDSE 83
>gi|4506001 protoporphyrinogen oxidase [Homo sapiens]
Length = 477
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 13 GPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSER-CFGGVVEVGAHWI 71
G V+V+GGGI+GL A+ L P + ++E++ R GG IRS R G + E+G I
Sbjct: 2 GRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPRGI 61
Query: 72 H-GPSRGNPVFQLAAEYGLLGE 92
+ G L +E GL E
Sbjct: 62 RPAGALGARTLLLVSELGLDSE 83
>gi|23821023 interleukin 4 induced 1 isoform 1 precursor [Homo
sapiens]
Length = 567
Score = 40.0 bits (92), Expect = 0.005
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 300 FDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPD 335
F PPLP EA+R++ + K+FL F PFW +
Sbjct: 332 FSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREE 367
Score = 36.6 bits (83), Expect = 0.053
Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 10/79 (12%)
Query: 15 RVLVVGGGIAGLGAAQRL--CGHSAFPHLRVLEATARAGGRIRS--ERCFGGVVEVGAHW 70
RV+VVG G+AGL AA+ L GH + +LEA R GGRI + ++ G + E+GA
Sbjct: 61 RVIVVGAGVAGLVAAKVLSDAGHK----VTILEADNRIGGRIFTYRDQNTGWIGELGA-- 114
Query: 71 IHGPSRGNPVFQLAAEYGL 89
+ PS + +L GL
Sbjct: 115 MRMPSSHRILHKLCQGLGL 133
>gi|27477089 interleukin 4 induced 1 isoform 2 [Homo sapiens]
Length = 589
Score = 40.0 bits (92), Expect = 0.005
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 300 FDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPD 335
F PPLP EA+R++ + K+FL F PFW +
Sbjct: 354 FSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREE 389
Score = 36.6 bits (83), Expect = 0.053
Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 10/79 (12%)
Query: 15 RVLVVGGGIAGLGAAQRL--CGHSAFPHLRVLEATARAGGRIRS--ERCFGGVVEVGAHW 70
RV+VVG G+AGL AA+ L GH + +LEA R GGRI + ++ G + E+GA
Sbjct: 83 RVIVVGAGVAGLVAAKVLSDAGHK----VTILEADNRIGGRIFTYRDQNTGWIGELGA-- 136
Query: 71 IHGPSRGNPVFQLAAEYGL 89
+ PS + +L GL
Sbjct: 137 MRMPSSHRILHKLCQGLGL 155
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 31.6 bits (70), Expect = 1.7
Identities = 31/120 (25%), Positives = 47/120 (39%), Gaps = 7/120 (5%)
Query: 369 VLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQ----VLRRVTAPDPVCGGSHTSH 424
V+ ++ L ++AG + D + L LT V+ V PVC T+H
Sbjct: 85 VIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCW---TAH 141
Query: 425 VLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLLTDFS 484
++ D V R S+ AA+ L G L C+ GG GPS + +S
Sbjct: 142 AIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYS 201
>gi|51036596 pyridine nucleotide-disulphide oxidoreductase domain
1 [Homo sapiens]
Length = 500
Score = 30.8 bits (68), Expect = 2.9
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Query: 11 PGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATA 48
P + +VVGGGIAG+ A++L H FP +L TA
Sbjct: 8 PTAGKFVVVGGGIAGVTCAEQLATH--FPSEDILLVTA 43
>gi|11560152 zinc finger protein 335 [Homo sapiens]
Length = 1342
Score = 30.8 bits (68), Expect = 2.9
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 3/34 (8%)
Query: 442 PPPQSVGPAGAAAQA---QALAGPSLLCSTRVGG 472
PPP S GP +A Q+ PSLLCS +GG
Sbjct: 742 PPPSSPGPPEIPPEATTFQSSEAPSLLCSDTLGG 775
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 30.4 bits (67), Expect = 3.8
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 411 TAPDPVCGGSHTSHVLLHDARGSAVG--MEGGRPPPQSVGPAGAAAQAQALAGPS 463
+ P P GG+ + L G + G G PP SV AGA A A A +GP+
Sbjct: 542 SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA-AGSGPA 595
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 30.4 bits (67), Expect = 3.8
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 411 TAPDPVCGGSHTSHVLLHDARGSAVG--MEGGRPPPQSVGPAGAAAQAQALAGPS 463
+ P P GG+ + L G + G G PP SV AGA A A A +GP+
Sbjct: 542 SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA-AGSGPA 595
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 30.4 bits (67), Expect = 3.8
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 411 TAPDPVCGGSHTSHVLLHDARGSAVG--MEGGRPPPQSVGPAGAAAQAQALAGPS 463
+ P P GG+ + L G + G G PP SV AGA A A A +GP+
Sbjct: 542 SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA-AGSGPA 595
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 30.4 bits (67), Expect = 3.8
Identities = 16/40 (40%), Positives = 16/40 (40%)
Query: 415 PVCGGSHTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAA 454
P G H LH R S G G PPP G G AA
Sbjct: 509 PRSSGGTPLHSPLHTPRASPTGTPGTTPPPSPGGGVGGAA 548
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 30.0 bits (66), Expect = 4.9
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 236 LPEDTVVFEKPVKTIHWNGSFQ-EAAFPGETFP----VSVECEDGDR-----FPAHHVIV 285
LP +T++ PV+ +G + E P E P V V+ EDGD+ PA +++
Sbjct: 416 LPAETLLLSSPVEVKGEDGDGEPEGTLPAEAPPPPPPVEVKGEDGDQEPEGTLPAETLLL 475
Query: 286 TVPLGFLREHLDTFFDPPLPAE 307
+ P+ E D + LPAE
Sbjct: 476 SPPVKVKGEDGDREPEGTLPAE 497
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 29.6 bits (65), Expect = 6.4
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 118 SGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVG 156
SG LQ A+L GL D +EFL A + PS+G
Sbjct: 76 SGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLG 114
>gi|119703746 electron-transferring-flavoprotein dehydrogenase
precursor [Homo sapiens]
Length = 617
Score = 29.6 bits (65), Expect = 6.4
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 16 VLVVGGGIAGLGAAQRL----CGHSAFPHLRVLEATARAGGRIRSERCF--GGVVEVGAH 69
V++VG G AGL AA RL H + ++E A+ G S C G E+
Sbjct: 71 VVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPD 130
Query: 70 WIHGPSRGNPVFQLAAE--YGLLGEK 93
W +G P+ E +G+L EK
Sbjct: 131 W---KEKGAPLNTPVTEDRFGILTEK 153
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 29.6 bits (65), Expect = 6.4
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 439 GGRPPPQSVGPAGAAAQAQALAGPSLLC--STRVGGRL 474
GG PPP P+ ++ QAQAL C R GGR+
Sbjct: 81 GGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRM 118
>gi|118600963 Nik related kinase [Homo sapiens]
Length = 1582
Score = 29.6 bits (65), Expect = 6.4
Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 133 LFYGLIDQTREF-----LHAAETPVPSVGEYLKKEIGQHVAGW--TEDEETRKLKLAVLN 185
++ GL ++T F ++A +TP+P +G ++ Q GW +++EE + +L +L
Sbjct: 39 IYLGLHEKTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLR 98
Query: 186 SF 187
+
Sbjct: 99 KY 100
>gi|239753767 PREDICTED: hypothetical protein [Homo sapiens]
Length = 70
Score = 29.3 bits (64), Expect = 8.4
Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 15/54 (27%)
Query: 415 PVCGGSHTSHVLLHDARGSAVG--MEGGRPPPQSVG--PAGAAAQAQALAGPSL 464
PVCGGS G V + GG PPP VG P +A +ALA P L
Sbjct: 28 PVCGGS-----------GMLVTGPVPGGSPPPAGVGKDPFHLSAAEEALAAPRL 70
>gi|239748329 PREDICTED: hypothetical protein [Homo sapiens]
Length = 70
Score = 29.3 bits (64), Expect = 8.4
Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 15/54 (27%)
Query: 415 PVCGGSHTSHVLLHDARGSAVG--MEGGRPPPQSVG--PAGAAAQAQALAGPSL 464
PVCGGS G V + GG PPP VG P +A +ALA P L
Sbjct: 28 PVCGGS-----------GMLVTGPVPGGSPPPAGVGKDPFHLSAAEEALAAPRL 70
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,083,264
Number of Sequences: 37866
Number of extensions: 1033432
Number of successful extensions: 3143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3084
Number of HSP's gapped (non-prelim): 47
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.